Sample records for automated stratigraphic structural

  1. Structural and Sequence Stratigraphic Analysis of the Onshore Nile Delta, Egypt.

    NASA Astrophysics Data System (ADS)

    Barakat, Moataz; Dominik, Wilhelm

    2010-05-01

    The Nile Delta is considered the earliest known delta in the world. It was already described by Herodotus in the 5th Century AC. Nowadays; the Nile Delta is an emerging giant gas province in the Middle East with proven gas reserves which have more than doubled in size in the last years. The Nile Delta basin contains a thick sedimentary sequence inferred to extend from Jurassic to recent time. Structural styles and depositional environments varied during this period. Facies architecture and sequence stratigraphy of the Nile Delta are resolved using seismic stratigraphy based on (2D seismic lines) including synthetic seismograms and tying in well log data. Synthetic seismograms were constructed using sonic and density logs. The combination of structural interpretation and sequence stratigraphy of the development of the basin was resolved. Seven chrono-stratigraphic boundaries have been identified and correlated on seismic and well log data. Several unconformity boundaries also identified on seismic lines range from angular to disconformity type. Furthermore, time structure maps, velocity maps, depth structure maps as well as Isopach maps were constructed using seismic lines and log data. Several structural features were identified: normal faults, growth faults, listric faults, secondary antithetic faults and large rotated fault blocks of manly Miocene age. In some cases minor rollover structures could be identified. Sedimentary features such as paleo-channels were distinctively recognized. Typical Sequence stratigraphic features such as incised valley, clinoforms, topsets, offlaps and onlaps are identified and traced on the seismic lines allowing a good insight into sequence stratigraphic history of the Nile Delta most especially in the Miocene to Pliocene clastic sedimentary succession.

  2. Automated recognition of stratigraphic marker shales from geophysical logs in iron ore deposits

    NASA Astrophysics Data System (ADS)

    Silversides, Katherine; Melkumyan, Arman; Wyman, Derek; Hatherly, Peter

    2015-04-01

    The mining of stratiform ore deposits requires a means of determining the location of stratigraphic boundaries. A variety of geophysical logs may provide the required data but, in the case of banded iron formation hosted iron ore deposits in the Hamersley Ranges of Western Australia, only one geophysical log type (natural gamma) is collected for this purpose. The information from these logs is currently processed by slow manual interpretation. In this paper we present an alternative method of automatically identifying recurring stratigraphic markers in natural gamma logs from multiple drill holes. Our approach is demonstrated using natural gamma geophysical logs that contain features corresponding to the presence of stratigraphically important marker shales. The host stratigraphic sequence is highly consistent throughout the Hamersley and the marker shales can therefore be used to identify the stratigraphic location of the banded iron formation (BIF) or BIF hosted ore. The marker shales are identified using Gaussian Processes (GP) trained by either manual or active learning methods and the results are compared to the existing geological interpretation. The manual method involves the user selecting the signatures for improving the library, whereas the active learning method uses the measure of uncertainty provided by the GP to select specific examples for the user to consider for addition. The results demonstrate that both GP methods can identify a feature, but the active learning approach has several benefits over the manual method. These benefits include greater accuracy in the identified signatures, faster library building, and an objective approach for selecting signatures that includes the full range of signatures across a deposit in the library. When using the active learning method, it was found that the current manual interpretation could be replaced in 78.4% of the holes with an accuracy of 95.7%.

  3. Using 3D visualization and seismic attributes to improve structural and stratigraphic resolution of reservoirs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerr, J.; Jones, G.L.

    1996-01-01

    Recent advances in hardware and software have given the interpreter and engineer new ways to view 3D seismic data and well bore information. Recent papers have also highlighted the use of various statistics and seismic attributes. By combining new 3D rendering technologies with recent trends in seismic analysis, the interpreter can improve the structural and stratigraphic resolution of hydrocarbon reservoirs. This paper gives several examples using 3D visualization to better define both the structural and stratigraphic aspects of several different structural types from around the world. Statistics, 3D visualization techniques and rapid animation are used to show complex faulting andmore » detailed channel systems. These systems would be difficult to map using either 2D or 3D data with conventional interpretation techniques.« less

  4. Using 3D visualization and seismic attributes to improve structural and stratigraphic resolution of reservoirs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerr, J.; Jones, G.L.

    1996-12-31

    Recent advances in hardware and software have given the interpreter and engineer new ways to view 3D seismic data and well bore information. Recent papers have also highlighted the use of various statistics and seismic attributes. By combining new 3D rendering technologies with recent trends in seismic analysis, the interpreter can improve the structural and stratigraphic resolution of hydrocarbon reservoirs. This paper gives several examples using 3D visualization to better define both the structural and stratigraphic aspects of several different structural types from around the world. Statistics, 3D visualization techniques and rapid animation are used to show complex faulting andmore » detailed channel systems. These systems would be difficult to map using either 2D or 3D data with conventional interpretation techniques.« less

  5. Cambrian-Ordovician Knox production in Ohio: Three case studies of structural-stratigraphic traps

    USGS Publications Warehouse

    Riley, R.A.; Wicks, J.; Thomas, Joan

    2002-01-01

    The Knox Dolomite (Cambrian-Ordovician) in Ohio consists of a mixed carbonate-siliciclastic sequence deposited in a tidal-flat to shallow-marine environment along a broad continental shelf. Knox hydrocarbon production occurs in porous sandstone and dolomite reservoirs in the Copper Ridge dolomite, Rose Run sandstone, and Beekmantown dolomite. In Ohio, historical Knox exploration and development have been focused on paleogeomorphic traps within the prolific Morrow Consolidated field, and more recently, within and adjacent to the Rose Run subcrop. Although these paleogeomorphic traps have yielded significant Knox production, structural and stratigraphic traps are being largely ignored. Three Knox-producing pools demonstrate structural and stratigraphic traps: the Birmingham-Erie pool in southern Erie and southwestern Lorain counties, the South Canaan pool in northern Wayne County, and the East Randolph pool in south-central Portage County. Enhanced porosity and permeability from fractures, as evident in the East Randolph pool, are also an underexplored mechanism for Knox hydrocarbon accumulation. An estimated 800 bcf of gas from undiscovered Knox resources makes the Knox one of the most attractive plays in the Appalachian basin.

  6. Fine reservoir structure modeling based upon 3D visualized stratigraphic correlation between horizontal wells: methodology and its application

    NASA Astrophysics Data System (ADS)

    Chenghua, Ou; Chaochun, Li; Siyuan, Huang; Sheng, James J.; Yuan, Xu

    2017-12-01

    As the platform-based horizontal well production mode has been widely applied in petroleum industry, building a reliable fine reservoir structure model by using horizontal well stratigraphic correlation has become very important. Horizontal wells usually extend between the upper and bottom boundaries of the target formation, with limited penetration points. Using these limited penetration points to conduct well deviation correction means the formation depth information obtained is not accurate, which makes it hard to build a fine structure model. In order to solve this problem, a method of fine reservoir structure modeling, based on 3D visualized stratigraphic correlation among horizontal wells, is proposed. This method can increase the accuracy when estimating the depth of the penetration points, and can also effectively predict the top and bottom interfaces in the horizontal penetrating section. Moreover, this method will greatly increase not only the number of points of depth data available, but also the accuracy of these data, which achieves the goal of building a reliable fine reservoir structure model by using the stratigraphic correlation among horizontal wells. Using this method, four 3D fine structure layer models have been successfully built of a specimen shale gas field with platform-based horizontal well production mode. The shale gas field is located to the east of Sichuan Basin, China; the successful application of the method has proven its feasibility and reliability.

  7. Structural and tectonic setting of the Charleston, South Carolina, region: Evidence from the Tertiary stratigraphic record

    USGS Publications Warehouse

    Weems, R.E.; Lewis, W.C.

    2002-01-01

    Eleven upper Eocene through Pliocene stratigraphic units occur in the subsurface of the region surrounding Charleston, South Carolina. These units contain a wealth of information concerning the long-term tectonic and structural setting of that area. These stratigraphic units have a mosaic pattern of distribution, rather than a simple layered pattern, because deposition, erosion, and tectonic warping have interacted in a complex manner through time. By generating separate structure-contour maps for the base of each stratigraphic unit, an estimate of the original basal surface of each unit can be reconstructed over wide areas. Changes in sea level over geologic time generate patterns of deposition and erosion that are geographically unique for the time of each transgression. Such patterns fail to persist when compared sequentially over time. In some areas, however, there has been persistent, repetitive net downward of upward movement over the past 34 m.y. These repetitive patterns of persistent motion are most readily attributable to tectonism. The spatial pattern of these high and low areas is complex, but it appears to correlate well with known tectonic features of the region. This correlation suggests that the tectonic setting of the Charleston region is controlled by scissors-like compression on a crustal block located between the north-trending Adams Run fault and the northwest-trending Charleston fault. Tectonism is localized in the Charleston region because it lies within a discrete hinge zone that accommodates structural movement between the Cape Fear arch and the Southeast Georgia embayment.

  8. Stratigraphic and structural evolution of the Selenga Delta Accommodation Zone, Lake Baikal Rift, Siberia

    USGS Publications Warehouse

    Scholz, C.A.; Hutchinson, D.R.

    2000-01-01

    Seismic reflection profiles from the Lake Baikal Rift reveal extensive details about the sediment thickness, structural geometry and history of extensional deformation and syn-rift sedimentation in this classic continental rift. The Selenga River is the largest single source of terrigenous input into Lake Baikal, and its large delta sits astride the major accommodation zone between the Central and South basins of the lake. Incorporating one of the world's largest lacustrine deltas, this depositional system is a classic example of the influence of rift basin structural segmentation on a major continental drainage. More than 3700 km of deep basin-scale multi-channel seismic reflection (MCS) data were acquired during the 1989 Russian and the 1992 Russian–American field programs. The seismic data image most of the sedimentary section, including pre-rift basement in several localities. The MCS data reveal that the broad bathymetric saddle between these two major half-graben basins is underlain by a complex of severely deformed basement blocks, and is not simply a consequence of long-term deltaic deposition. Maximum sediment thickness is estimated to be more than 9 km in some areas around the Selenga Delta. Detailed stratigraphic analyses of the Selenga area MCS data suggest that modes of deposition have shifted markedly during the history of the delta. The present mode of gravity- and mass-flow sedimentation that dominates the northern and southern parts of the modern delta, as well as the pronounced bathymetric relief in the area, are relatively recent developments in the history of the Lake Baikal Rift. Several episodes of major delta progradation, each extending far across the modern rift, can be documented in the MCS data. The stratigraphic framework defined by these prograding deltaic sequences can be used to constrain the structural as well as depositional evolution of this part of the Baikal Rift. An age model has been established for this stratigraphy, by

  9. Stratigraphic and structural evolution of the Selenga Delta Accommodation Zone, Lake Baikal Rift, Siberia

    NASA Astrophysics Data System (ADS)

    Scholz, C. A.; Hutchinson, D. R.

    Seismic reflection profiles from the Lake Baikal Rift reveal extensive details about the sediment thickness, structural geometry and history of extensional deformation and syn-rift sedimentation in this classic continental rift. The Selenga River is the largest single source of terrigenous input into Lake Baikal, and its large delta sits astride the major accommodation zone between the Central and South basins of the lake. Incorporating one of the world's largest lacustrine deltas, this depositional system is a classic example of the influence of rift basin structural segmentation on a major continental drainage. More than 3700km of deep basin-scale multi-channel seismic reflection (MCS) data were acquired during the 1989 Russian and the 1992 Russian-American field programs. The seismic data image most of the sedimentary section, including pre-rift basement in several localities. The MCS data reveal that the broad bathymetric saddle between these two major half-graben basins is underlain by a complex of severely deformed basement blocks, and is not simply a consequence of long-term deltaic deposition. Maximum sediment thickness is estimated to be more than 9km in some areas around the Selenga Delta. Detailed stratigraphic analyses of the Selenga area MCS data suggest that modes of deposition have shifted markedly during the history of the delta. The present mode of gravity- and mass-flow sedimentation that dominates the northern and southern parts of the modern delta, as well as the pronounced bathymetric relief in the area, are relatively recent developments in the history of the Lake Baikal Rift. Several episodes of major delta progradation, each extending far across the modern rift, can be documented in the MCS data. The stratigraphic framework defined by these prograding deltaic sequences can be used to constrain the structural as well as depositional evolution of this part of the Baikal Rift. An age model has been established for this stratigraphy, by tying

  10. Structural styles of the paradox basin: Something to consider in a basin dominated by stratigraphic traps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stevenson, G.M.

    1993-08-01

    The Paradox basin has produced a considerable amount of oil and gas from Pennsylvanian and Mississippian reservoirs. Most of the production has been from stratigraphic traps associated with subtle rejuvenated basement structures. Only the Blanding sub-basin and west flank of the salt anticlines (Lisbon Valley to Salt Wash fields) have been explored in sufficient quantity to classify as the mature parts of the basin, and even in these areas, new fields are currently being discovered. The majority of the basin still remains an exploration frontier. Certainly, structural and stratigraphic conditions analogous to those in the proven areas exist in muchmore » of these underexplored parts of the Paradox basin, but the potential for new and different types of hydrocarbon traps should not be overlooked. Structural styles present in the Paradox basin range from high-angle reverse, to normal, to inverted, which records different periods of crustal shortening and extension. To provide a full appreciation of the variety and complexities of structural styles in the Paradox basin and their influence on the orientation and distribution of different stratigraphic mechanisms, comparisons are made in the following areas: the Uncompahgre frontal fault zone, salt anticlines, Cane Creek anticline, Nequoia arch, Blanding basin, and Hogback monocline. To demonstrate the episodic nature of tectonism throughout the entire Phanerozoic Era, potential and proven hydrocarbon trapping styles are illustrated in strata ranging from Devonian to Late Pennsylvanian age. In particular, the Pennsylvanian Paradox evaporites and equivalent shelf carbonates and siliciclastics provide an excellent example of chronostratigraphic and glacioeustatic relationships. Due to the proven prolific nature of these Pennsylvanian reservoirs, the interrelationships of structure to stratigraphy in the Blanding basin and along the Cane Creek anticline will be emphasized.« less

  11. Automation of NMR structure determination of proteins.

    PubMed

    Altieri, Amanda S; Byrd, R Andrew

    2004-10-01

    The automation of protein structure determination using NMR is coming of age. The tedious processes of resonance assignment, followed by assignment of NOE (nuclear Overhauser enhancement) interactions (now intertwined with structure calculation), assembly of input files for structure calculation, intermediate analyses of incorrect assignments and bad input data, and finally structure validation are all being automated with sophisticated software tools. The robustness of the different approaches continues to deal with problems of completeness and uniqueness; nevertheless, the future is very bright for automation of NMR structure generation to approach the levels found in X-ray crystallography. Currently, near completely automated structure determination is possible for small proteins, and the prospect for medium-sized and large proteins is good. Copyright 2004 Elsevier Ltd.

  12. NMR-based automated protein structure determination.

    PubMed

    Würz, Julia M; Kazemi, Sina; Schmidt, Elena; Bagaria, Anurag; Güntert, Peter

    2017-08-15

    NMR spectra analysis for protein structure determination can now in many cases be performed by automated computational methods. This overview of the computational methods for NMR protein structure analysis presents recent automated methods for signal identification in multidimensional NMR spectra, sequence-specific resonance assignment, collection of conformational restraints, and structure calculation, as implemented in the CYANA software package. These algorithms are sufficiently reliable and integrated into one software package to enable the fully automated structure determination of proteins starting from NMR spectra without manual interventions or corrections at intermediate steps, with an accuracy of 1-2 Å backbone RMSD in comparison with manually solved reference structures. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Stratigraphic and structural configuration of the Navajo (Jurassic) through Ouray (Mississippian-Devonian) formations in the vicinity of Davis and Lavender Canyons, southeastern Utah

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCleary, J.R.; Romie, J.E.

    1986-04-01

    This study developed a three-dimensional computer model of stratigraphic and structural relationships within a 3497-km/sup 2/ (1350-mi/sup 2/) study area centered on the proposed site for a high-level nuclear waste repository in southeastern Utah. The model consists of a sequence of internally reconciled isopach and structure contour maps horizontally registered and stored in stratigraphic order. This model can be used to display cross sections, perspective block diagrams, or fence diagrams at any orientation; estimate depth of formation contacts and thicknesses for any new stratigraphic or hydrologic boreholes; facilitate ground-water modeling studies; and evaluate the structural and stratigraphic evolution of themore » study area. This study also includes limited evaluations of aquifer continuity in the Elephant Canyon and Honaker Trail Formations, and of salt dissolution and flowage features as interpreted from geophysical logs. The study identified a long history of movement in the fault system in the north-central part of the study area and a major salt flowage feature in the northeastern part. It describes the Elephant Canyon Formation aquifer as laterally limited, the Honaker Trail Formation aquifer as fairly continuous over the area, and Beef Basin in the southern part of the area as a probable dissolution feature. It also concludes that the Shay-Bridger Jack-Salt Creek Graben system is apparently a vertically continuous feature between the basement and ground surface. No stratigraphic or structural discontinuities were detected in the vicinity of Davis Canyon that appear to be detrimental to the siting of a waste repository.« less

  14. North American Commission on Stratigraphic Nomenclature Note 66: records of Stratigraphic Commission, 2003-2013

    USGS Publications Warehouse

    Easton, Robert M.; Catuneanu, Octavian; Donovan, Art D.; Fluegeman, Richard H.; Hamblin, A.P.; Harper, Howard; Lasca, Norman P.; Morrow, Jared R.; Orndorff, Randall C.; Sadler, Peter; Scott, Robert W.; Tew, Berry H.

    2014-01-01

    Note 66 summarizes activities of the North American Commission on Stratigraphic Nomenclature (NACSN) from November 2003 to October 2013 and is condensed from the minutes of the NACSN’s 58th to 68th annual meetings1. The purposes of the Commission are to develop statements of stratigraphic principles,recommend procedures applicable to the classification and nomenclature of stratigraphic and related units, review problems in classifying and naming stratigraphic and related units, and formulate expressions of judgment on these matters.

  15. Automated MAD and MIR structure solution

    PubMed Central

    Terwilliger, Thomas C.; Berendzen, Joel

    1999-01-01

    Obtaining an electron-density map from X-ray diffraction data can be difficult and time-consuming even after the data have been collected, largely because MIR and MAD structure determinations currently require many subjective evaluations of the qualities of trial heavy-atom partial structures before a correct heavy-atom solution is obtained. A set of criteria for evaluating the quality of heavy-atom partial solutions in macromolecular crystallography have been developed. These have allowed the conversion of the crystal structure-solution process into an optimization problem and have allowed its automation. The SOLVE software has been used to solve MAD data sets with as many as 52 selenium sites in the asymmetric unit. The automated structure-solution process developed is a major step towards the fully automated structure-determination, model-building and refinement procedure which is needed for genomic scale structure determinations. PMID:10089316

  16. ASTROS: A multidisciplinary automated structural design tool

    NASA Technical Reports Server (NTRS)

    Neill, D. J.

    1989-01-01

    ASTROS (Automated Structural Optimization System) is a finite-element-based multidisciplinary structural optimization procedure developed under Air Force sponsorship to perform automated preliminary structural design. The design task is the determination of the structural sizes that provide an optimal structure while satisfying numerous constraints from many disciplines. In addition to its automated design features, ASTROS provides a general transient and frequency response capability, as well as a special feature to perform a transient analysis of a vehicle subjected to a nuclear blast. The motivation for the development of a single multidisciplinary design tool is that such a tool can provide improved structural designs in less time than is currently needed. The role of such a tool is even more apparent as modern materials come into widespread use. Balancing conflicting requirements for the structure's strength and stiffness while exploiting the benefits of material anisotropy is perhaps an impossible task without assistance from an automated design tool. Finally, the use of a single tool can bring the design task into better focus among design team members, thereby improving their insight into the overall task.

  17. Automated procedures for sizing aerospace vehicle structures /SAVES/

    NASA Technical Reports Server (NTRS)

    Giles, G. L.; Blackburn, C. L.; Dixon, S. C.

    1972-01-01

    Results from a continuing effort to develop automated methods for structural design are described. A system of computer programs presently under development called SAVES is intended to automate the preliminary structural design of a complete aerospace vehicle. Each step in the automated design process of the SAVES system of programs is discussed, with emphasis placed on use of automated routines for generation of finite-element models. The versatility of these routines is demonstrated by structural models generated for a space shuttle orbiter, an advanced technology transport,n hydrogen fueled Mach 3 transport. Illustrative numerical results are presented for the Mach 3 transport wing.

  18. Triassic structural and stratigraphic evolution of the Central German North Sea sector

    NASA Astrophysics Data System (ADS)

    Wolf, Marco; Jähne-Klingberg, Fabian

    2017-04-01

    The subsurface of the Central German North Sea sector is characterized by a complex sequence of tectonic events that span from the Permo-Carboniferous initiation of the Southern Permian Basin to the present day. The Triassic period is one of the most prominent stratigraphic intervals in this area due to alternating phases of relatively tectonic quiescence and intense tectonic activity with the development of grabens, salt-tectonics movements, various regional and local erosional events and strong local and regional changes in subsidence over time. The heterogeneous geological history led to complex structural and lithological patterns. The presented results are part of a comprehensive investigation of the Central German North Sea sector. It was carried out within the scope of the project TUNB (www.bgr.bund.de). The main goal was to enhance the understanding of the Triassic geological development in the area of interest due to detailed seismic interpretation of several hundred 2D seismic lines and as well 3D seismic data sets. A seismostratigraphic concept was used to interpret most formations of the Triassic resulting in a detailed subdivision of the Triassic unit. Depth and thickness maps for every stratigraphic unit and geological cross sections provided new insights regarding an overall basin evolution as well as the timing and mechanisms of rifting and salt-tectonics. New results concerning the evolution of the Keuper in the German North Sea and especially the Triassic evolution of the Horn Graben, as one of the major Triassic rift-structures in the North Sea, will be highlighted. We will show aspects of strong tectonic subsidence in the Horn Graben in the Lower Triassic. In parts of the study area, halotectonic movements started in the Upper Triassic, earlier than previously proposed. Besides mapping of regional seismic reflectors, distinct sedimentary features like fluvial channel systems of the Stuttgart formation (Middle Keuper) or subrosion-like structures

  19. Aeolian sedimentary processes at the Bagnold Dunes, Mars: Implications for modern dune dynamics and sedimentary structures in the aeolian stratigraphic record of Mars

    NASA Astrophysics Data System (ADS)

    Ewing, Ryan C.; Bridges, Nathan T.; Sullivan, Rob; Lapotre, Mathieu G. A.; Fischer, Woodward W.; Lamb, Mike P.; Rubin, David M.; Lewis, Kevin W.; Gupta, Sanjeev

    2016-04-01

    Wind-blown sand dunes are ubiquitous on the surface of Mars and are a recognized component of the martian stratigraphic record. Our current knowledge of the aeolian sedimentary processes that determine dune morphology, drive dune dynamics, and create aeolian cross-stratification are based upon orbital studies of ripple and dune morphodynamics, rover observations of stratification on Mars, Earth analogs, and experimental and theoretical studies of sand movement under Martian conditions. In-situ observations of sand dunes (informally called the Bagnold Dunes) by Curiosity Rover in Gale Crater, Mars provide the first opportunity to make observations of dunes from the grain-to-dune scale thereby filling the gap in knowledge between theory and orbital observations and refining our understanding of the martian aeolian stratigraphic record. We use the suite of cameras on Curiosity, including Navigation Camera (Navcam), Mast Camera (Mastcam) and Mars Hand Lens Imager (MAHLI), to make observations of the Bagnold Dunes. Measurements of sedimentary structures are made where stereo images are available. Observations indicate that structures generated by gravity-driven processes on the dune lee slopes, such as grainflow and grainfall, are similar to the suite of aeolian sedimentary structures observed on Earth and should be present and recognizable in Mars' aeolian stratigraphic record. Structures formed by traction-driven processes deviate significantly from those found on Earth. The dune hosts centimeter-scale wind ripples and large, meter-scale ripples, which are not found on Earth. The large ripples migrate across the depositional, lee slopes of the dune, which implies that these structures should be present in Mars' stratigraphic record and may appear similar to compound-dune stratification.The Mars Science Laboratory Curiosity Rover Team is acknowledged for their support of this work.

  20. Subsurface geology of the Lusi region: preliminary results from a comprehensive seismic-stratigraphic study.

    NASA Astrophysics Data System (ADS)

    Moscariello, Andrea; Do Couto, Damien; Lupi, Matteo; Mazzini, Adriano

    2016-04-01

    We investigate the subsurface data of a large sector in the Sidoarjo district (East Java, Indonesia) where the sudden catastrophic Lusi eruption started the 26th May 2006. Our goal is to understand the stratigraphic and structural features which can be genetically related to the surface manifestations of deep hydrothermal fluids and thus allow us to predict possible future similar phenomena in the region. In the framework of the Lusi Lab project (ERC grant n° 308126) we examined a series of densely spaced 2D reflection commercial seismic lines This allowed the reconstruction of the lateral variability of key stratigraphic horizons as well as the main tectonic features. In particular, we shed light on the deep structure of the Watukosek fault system and the associated fracture corridors crossing the entire stratigraphic successions. To the South-West, when approaching the volcanic complex, we could identify a clear contrast in seismic facies between chaotic volcanoclastic wedges and clastic-prone sedimentary successions as well as between the deeper stratigraphic units consisting of carbonates and lateral shales units. The latter show possible ductile deformation associated to fault-controlled diapirism which control in turns deformation of overlying stratigraphic units and deep geo-fluids circulation. Large collapse structures recognized in the study area (e.g. well PRG-1) are interpreted as the results of shale movement at depth. Similarly to Lusi, vertical deformation zones ("pipes"), likely associated with deeply rooted strike-slip systems seem to be often located at the interface between harder carbonate rocks forming isolated build ups and the laterally nearby clastic (shale-prone)-units. The mechanisms of deformation of structural features (strike vs dip slip systems) which may affect either the basement rock or the overlying deeper stratigraphic rocks is also being investigated to understand the relationship between deep and shallower (i.e. meteoric) fluid

  1. Automated Tape Laying Machine for Composite Structures.

    DTIC Science & Technology

    The invention comprises an automated tape laying machine, for laying tape on a composite structure. The tape laying machine has a tape laying head...neatly cut. The automated tape laying device utilizes narrow width tape to increase machine flexibility and reduce wastage.

  2. Stratigraphic and structural characterization of the OU-1 area at the former George Air Force Base, Adelanto, Southern California

    USGS Publications Warehouse

    Catchings, R.D.; Gandhok, G.; Goldman, M.R.

    2001-01-01

    The former George Air Force Base (GAFB), now known as the Southern California Logistics Airport (SCLA), is located in the town of Adelanto, approximately 100 km northeast of Los Angeles, California (Fig. 1). In this report, we present acquisition parameters, data, and interpretations of seismic images that were acquired in the OU-1 area of GAFB during July 1999 (Fig. 2). GAFB is scheduled for conversion to civilian use, however, during its years as an Air Force base, trichlorethylene (TCE) was apparently introduced into the subsurface as a result of spills during normal aircraft maintenance operations. To comply with congressional directives, TCE contaminant removal has been ongoing since the early-tomid 1990s. However, only a small percentage of the TCE believed to have been introduced into the subsurface has been recovered, due largely to difficulty in locating the TCE within the subsurface. Because TCE migrates within the subsurface by ground water movement, attempts to locate the TCE contaminants in the subsurface have employed an array of ground-water monitoring and extraction wells. These wells primarily sample within a shallow-depth (~40 m) aquifer system. Cores obtained from the monitoring and extraction wells indicate that the aquifer, which is composed of sand and gravel channels, is bounded by aquitards composed largely of clay and other fine-grained sediments. Based on well logs, the aquifer is about 3 to 5 m thick along the seismic profiles. A more thorough understanding of the lateral variations in the depth and thickness of the aquifer system may be a key to finding and removing the remaining TCE. However, due to its complex depositional and tectonic history, the structural and stratigraphic sequences are not easily characterized. An indication of the complex nature of the structure and stratigraphy is the appreciable variation in stratigraphic sequences observed in some monitoring wells that are only a few tens of meters apart. To better

  3. Automated structure solution, density modification and model building.

    PubMed

    Terwilliger, Thomas C

    2002-11-01

    The approaches that form the basis of automated structure solution in SOLVE and RESOLVE are described. The use of a scoring scheme to convert decision making in macromolecular structure solution to an optimization problem has proven very useful and in many cases a single clear heavy-atom solution can be obtained and used for phasing. Statistical density modification is well suited to an automated approach to structure solution because the method is relatively insensitive to choices of numbers of cycles and solvent content. The detection of non-crystallographic symmetry (NCS) in heavy-atom sites and checking of potential NCS operations against the electron-density map has proven to be a reliable method for identification of NCS in most cases. Automated model building beginning with an FFT-based search for helices and sheets has been successful in automated model building for maps with resolutions as low as 3 A. The entire process can be carried out in a fully automatic fashion in many cases.

  4. Some debatable problems of stratigraphic classification

    NASA Astrophysics Data System (ADS)

    Gladenkov, Yury

    2014-05-01

    Russian geologists perform large-scale geological mapping in Russia and abroad. Therefore we urge unification of legends of geological maps compiled in different countries. It seems important to continuously organize discussions on problems of stratigraphic classification. 1. The stratigraphic schools (conventionally called "European" and "American") define "stratigraphy" in different ways. The former prefers "single" stratigraphy that uses data proved by many methods. The latter divides stratigraphy into several independent stratigraphers (litho-, bio-, magneto- and others). Russian geologists classify stratigraphic units into general (chronostratigraphic) and special (in accordance with a method applied). 2. There exist different interpretations of chronostratigraphy. Some stratigraphers suppose that a chronostratigraphic unit corresponds to rock strata formed during a certain time interval (it is somewhat formalistic because a length of interval is frequently unspecified). Russian specialists emphasize the historical-geological background of chronostratigraphic units. Every stratigraphic unit (global and regional) reflects a stage of geological evolution of biosphere and stratisphere. 3. In the view of Russian stratigraphers, the main stratigraphic units may have different extent: a) global (stage), b) regional (regional stage,local zone), and c) local (suite). There is no such hierarchy in the ISG. 4. Russian specialists think that local "lithostratigraphic" units (formations) which may have diachronous boundaries are not chronostratigraphic ones in strict sense (actually they are lithological bodies). In this case "lithostratigraphy" can be considered as "prostratigraphy" and employed in initial studies of sequences. Therefore, a suite is a main local unit of the Russian Code and differs from a formation, although it is somewhat similar. It does not mean that lithostratigraphy is unnecessary. Usage of marker horizons, members and other bodies is of great help

  5. Automated protein NMR structure determination using wavelet de-noised NOESY spectra.

    PubMed

    Dancea, Felician; Günther, Ulrich

    2005-11-01

    A major time-consuming step of protein NMR structure determination is the generation of reliable NOESY cross peak lists which usually requires a significant amount of manual interaction. Here we present a new algorithm for automated peak picking involving wavelet de-noised NOESY spectra in a process where the identification of peaks is coupled to automated structure determination. The core of this method is the generation of incremental peak lists by applying different wavelet de-noising procedures which yield peak lists of a different noise content. In combination with additional filters which probe the consistency of the peak lists, good convergence of the NOESY-based automated structure determination could be achieved. These algorithms were implemented in the context of the ARIA software for automated NOE assignment and structure determination and were validated for a polysulfide-sulfur transferase protein of known structure. The procedures presented here should be commonly applicable for efficient protein NMR structure determination and automated NMR peak picking.

  6. A preliminary synthesis of structural, stratigraphic, and magnetic data from part of the northwest Adirondacks, New York

    USGS Publications Warehouse

    Foose, M.P.; Brown, C. Ervin

    1976-01-01

    Synthesis of recent work in the NW Adirondacks, New York allows the development of a coherent geologic picture. Mapping of the Precambrian rock units enables the recognition of four major units which are, from bottom to top, 1) Granitic Gneiss (alaskite), 2) Lower Marble, 3) Major Gneiss, and 4) Upper Marble. Additionally, lenses of amphibolite and granite occur as intrusives within this succession. These rock units have been complexly deformed by three major folding episodes, and by two distinctly different styles of faulting. The result has been to produce large northeast-southwest trending dome and basin structures. Patterns of magnetic intensity closely parallel distribution of rock units and provide additional information for a structural and stratigraphic synthesis-.

  7. Numeric stratigraphic modeling: Testing sequence Numeric stratigraphic modeling: Testing sequence stratigraphic concepts using high resolution geologic examples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Armentrout, J.M.; Smith-Rouch, L.S.; Bowman, S.A.

    1996-08-01

    Numeric simulations based on integrated data sets enhance our understanding of depositional geometry and facilitate quantification of depositional processes. Numeric values tested against well-constrained geologic data sets can then be used in iterations testing each variable, and in predicting lithofacies distributions under various depositional scenarios using the principles of sequence stratigraphic analysis. The stratigraphic modeling software provides a broad spectrum of techniques for modeling and testing elements of the petroleum system. Using well-constrained geologic examples, variations in depositional geometry and lithofacies distributions between different tectonic settings (passive vs. active margin) and climate regimes (hothouse vs. icehouse) can provide insight tomore » potential source rock and reservoir rock distribution, maturation timing, migration pathways, and trap formation. Two data sets are used to illustrate such variations: both include a seismic reflection profile calibrated by multiple wells. The first is a Pennsylvanian mixed carbonate-siliciclastic system in the Paradox basin, and the second a Pliocene-Pleistocene siliciclastic system in the Gulf of Mexico. Numeric simulations result in geometry and facies distributions consistent with those interpreted using the integrated stratigraphic analysis of the calibrated seismic profiles. An exception occurs in the Gulf of Mexico study where the simulated sediment thickness from 3.8 to 1.6 Ma within an upper slope minibasin was less than that mapped using a regional seismic grid. Regional depositional patterns demonstrate that this extra thickness was probably sourced from out of the plane of the modeled transect, illustrating the necessity for three-dimensional constraints on two-dimensional modeling.« less

  8. Colorstratigraphy; A New Stratigraphic Correlation Technique

    NASA Astrophysics Data System (ADS)

    Nanayakkara, N. U.; Ranasinghage, P. N.; Priyantha, C.; Abillapitiya, T.

    2016-12-01

    Here we introduce a novel stratigraphic technique namely colorstratigraphy for correlating sedimentary sequences. Minihagalkanda is about 1 km long amphitheater like sedimentary terrain, situated at the southeastern coast of Sri Lanka. It has Miocene sedimentary sequences, separated in to 10-12 m high small hillocks by erosion, and bounded by about 30 m high escarpment. Sandstone, yellowish sandy clay, greenish silty clay sequences are capped by 4-5 m limestone bed in these hillocks but not at the boundary escarpment. Stratigraphic profiles at two hillocks and the boundary escarpment, separated each other by 200-300 m, were selected to test the new colorstartigraphic correlation technique. Color reflectance (DSR) was measured at four samples in each sequence at every profile and hence altogether 36 reflectance measurements were taken using Minolta 2500D hand-held color spectrophotometer. The first-derivative of the reflectance spectra (dR/dλ) defines the "spectral shape" of the sample. Therefore, DSR data (360-740 nm) measured at 10 nm resolution were used to calculate a center-weighted, first-derivative spectra for each reflectance sample consisting of 39 channels. Particle size of each sequence was measured at all 03 profiles using laser particle size analyzer to verify the stratigraphic correlation. Mean reflectance spectrum for each sequence at all 03 profiles were plotted on the same graph for comparison. Same was done for the grain size spectrums. Discriminant function analysis was performed separately for dsr data and grain size data using a number assigned to each sedimentary sequence as the grouping variable Color spectrums of sandstone, yellowish sandy clay, and greenish silty clay sequences at all three profiles perfectly match showing clear stratigraphic correlation among these three stratigraphic profiles. Matching grain size distribution curves of the three sequence at the three profiles verify the stratigraphic correlation. Perfect 100

  9. Application of TIMS data in stratigraphic analysis

    NASA Technical Reports Server (NTRS)

    Lang, H. R.

    1986-01-01

    An in-progress study demonstrates the utility of Thermal Infrared Multispectral Scanner (TIMS) data for unraveling the stratigraphic sequence of a western interior, North American foreland basin. The TIMS data can be used to determine the stratigraphic distribution of minerals that are diagnostic of specific depositional distribution. The thematic mapper (TM) and TIMS data were acquired in the Wind River/Bighorn area of central Wyoming in November 1982, and July 1983, respectively. Combined image processing, photogeologic, and spectral analysis methods were used to: map strata; construct stratigraphic columns; correlate data; and identify mineralogical facies.

  10. The Phenix Software for Automated Determination of Macromolecular Structures

    PubMed Central

    Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor; Chen, Vincent B.; Echols, Nathaniel; Headd, Jeffrey J.; Hung, Li-Wei; Jain, Swati; Kapral, Gary J.; Grosse Kunstleve, Ralf W.; McCoy, Airlie J.; Moriarty, Nigel W.; Oeffner, Robert D.; Read, Randy J.; Richardson, David C.; Richardson, Jane S.; Terwilliger, Thomas C.; Zwart, Peter H.

    2011-01-01

    X-ray crystallography is a critical tool in the study of biological systems. It is able to provide information that has been a prerequisite to understanding the fundamentals of life. It is also a method that is central to the development of new therapeutics for human disease. Significant time and effort are required to determine and optimize many macromolecular structures because of the need for manual interpretation of complex numerical data, often using many different software packages, and the repeated use of interactive three-dimensional graphics. The Phenix software package has been developed to provide a comprehensive system for macromolecular crystallographic structure solution with an emphasis on automation. This has required the development of new algorithms that minimize or eliminate subjective input in favour of built-in expert-systems knowledge, the automation of procedures that are traditionally performed by hand, and the development of a computational framework that allows a tight integration between the algorithms. The application of automated methods is particularly appropriate in the field of structural proteomics, where high throughput is desired. Features in Phenix for the automation of experimental phasing with subsequent model building, molecular replacement, structure refinement and validation are described and examples given of running Phenix from both the command line and graphical user interface. PMID:21821126

  11. High Resolution Stratigraphic Mapping in Complex Terrain: A Comparison of Traditional Remote Sensing Techniques with Unmanned Aerial Vehicle - Structure from Motion Photogrammetry

    NASA Astrophysics Data System (ADS)

    Nesbit, P. R.; Hugenholtz, C.; Durkin, P.; Hubbard, S. M.; Kucharczyk, M.; Barchyn, T.

    2016-12-01

    Remote sensing and digital mapping have started to revolutionize geologic mapping in recent years as a result of their realized potential to provide high resolution 3D models of outcrops to assist with interpretation, visualization, and obtaining accurate measurements of inaccessible areas. However, in stratigraphic mapping applications in complex terrain, it is difficult to acquire information with sufficient detail at a wide spatial coverage with conventional techniques. We demonstrate the potential of a UAV and Structure from Motion (SfM) photogrammetric approach for improving 3D stratigraphic mapping applications within a complex badland topography. Our case study is performed in Dinosaur Provincial Park (Alberta, Canada), mapping late Cretaceous fluvial meander belt deposits of the Dinosaur Park formation amidst a succession of steeply sloping hills and abundant drainages - creating a challenge for stratigraphic mapping. The UAV-SfM dataset (2 cm spatial resolution) is compared directly with a combined satellite and aerial LiDAR dataset (30 cm spatial resolution) to reveal advantages and limitations of each dataset before presenting a unique workflow that utilizes the dense point cloud from the UAV-SfM dataset for analysis. The UAV-SfM dense point cloud minimizes distortion, preserves 3D structure, and records an RGB attribute - adding potential value in future studies. The proposed UAV-SfM workflow allows for high spatial resolution remote sensing of stratigraphy in complex topographic environments. This extended capability can add value to field observations and has the potential to be integrated with subsurface petroleum models.

  12. Syndepositional tectonics recorded by soft-sediment deformation and liquefaction structures (continental Lower Permian sediments, Southern Alps, Northern Italy): Stratigraphic significance

    NASA Astrophysics Data System (ADS)

    Berra, F.; Felletti, F.

    2011-04-01

    The Lower Permian succession of the Central Southern Alps (Lombardy, Northern Italy) was deposited in fault-controlled continental basins, probably related to transtensional tectonics. We focussed our study on the stratigraphic record of the Lower Permian Orobic Basin, which consists of a 1000 m thick succession of prevailing continental clastics with intercalations of ignimbritic flows and tuffs (Pizzo del Diavolo Formation, PDV) resting on the underlying prevailing pyroclastic flows of the Cabianca Volcanite. The PDV consists of a lower part (composed of conglomerates passing laterally to sandstones and distally to silt and shales), a middle part (pelitic, with carbonates) and an upper part (alternating sandstone, silt and volcanic flows). Syndepositional tectonics during the deposition of the PDV is recorded by facies distribution, thickness changes and by the presence of deformation and liquefaction structures interpreted as seismites. Deformation is recorded by both ductile structures (ball-and-pillow, plastic intrusion, disturbed lamination, convolute stratification and slumps) and brittle structures (sand dykes and autoclastic breccias). Both the sedimentological features and the geodynamic setting of the depositional basin confidently support the interpretation of the described deformation features as related to seismic shocks. The most significant seismically-induced deformation is represented by a slumped horizon (about 4 m thick on average) which can be followed laterally for more than 5 km. The slumped bed consists of playa-lake deposits (alternating pelites and microbial carbonates, associated with mud cracks and vertebrate tracks). The lateral continuity and the evidence of deposition on a very low-angle surface along with the deformation/liquefaction of the sediments suggest that the slump was triggered by a high-magnitude earthquake. The stratigraphic distribution of the seismites allows us to identify time intervals of intense seismic activity

  13. SDAR 1.0 a New Quantitative Toolkit for Analyze Stratigraphic Data

    NASA Astrophysics Data System (ADS)

    Ortiz, John; Moreno, Carlos; Cardenas, Andres; Jaramillo, Carlos

    2015-04-01

    Since the foundation of stratigraphy geoscientists have recognized that data obtained from stratigraphic columns (SC), two dimensional schemes recording descriptions of both geological and paleontological features (e.g., thickness of rock packages, grain size, fossil and lithological components, and sedimentary structures), are key elements for establishing reliable hypotheses about the distribution in space and time of rock sequences, and ancient sedimentary environmental and paleobiological dynamics. Despite the tremendous advances on the way geoscientists store, plot, and quantitatively analyze sedimentological and paleontological data (e.g., Macrostrat [http://www.macrostrat.org/], Paleobiology Database [http://www.paleodb.org/], respectively), there is still a lack of computational methodologies designed to quantitatively examine data from a highly detailed SCs. Moreover, frequently the stratigraphic information is plotted "manually" using vector graphics editors (e.g., Corel Draw, Illustrator), however, this information although store on a digital format, cannot be used readily for any quantitative analysis. Therefore, any attempt to examine the stratigraphic data in an analytical fashion necessarily takes further steps. Given these issues, we have developed the sofware 'Stratigraphic Data Analysis in R' (SDAR), which stores in a database all sedimentological, stratigraphic, and paleontological information collected from a SC, allowing users to generate high-quality graphic plots (including one or multiple features stored in the database). SDAR also encompasses quantitative analyses helping users to quantify stratigraphic information (e.g. grain size, sorting and rounding, proportion of sand/shale). Finally, given that the SDAR analysis module, has been written in the open-source high-level computer language "R graphics/statistics language" [R Development Core Team, 2014], it is already loaded with many of the crucial features required to accomplish basic and

  14. Stratigraphic and structural relationships between Meso-Cenozoic Lagonegro basin and coeval carbonate platforms in southern Apennines, Italy

    NASA Astrophysics Data System (ADS)

    Pescatore, Tullio; Renda, Pietro; Schiattarella, Marcello; Tramutoli, Mariano

    1999-12-01

    Stratigraphic studies and facies analysis integrated with a new geological and structural survey of the Meso-Cenozoic units outcropping in the Campania-Lucania Apennines, southern Italy, allowed us to restore the palaeogeographic pattern and the tectonic evolution of the chain during Oligo-Miocene times. The southern Apennines are a N150°-striking and NE-verging fold-and-thrust belt mainly derived from the deformation of the African-Apulian passive margin. Four wide belts with different features have been recognized in the chain area. From east to west the following units outcrop: (a) successions characterized by basinal to marginal facies, ranging in age from Cretaceous to Miocene, tectonically lying on Plio-Pleistocene foredeep deposits; (b) successions characterized by shallow-water, basinal and shelf-margin facies, ranging in age from middle Triassic to Miocene ('Lagonegro units'), overthrust on the previous ones; (c) Triassic to Miocene carbonate platform successions ('Apenninic platform units'), overthrust on the Lagonegro units; (d) Jurassic-Cretaceous to Miocene deep-water successions (ophiolite-bearing or 'internal' units and associated siliciclastic wedges), outcropping along the Tyrrhenian belt and the Calabria-Lucania boundary, overthrust on the Apenninic platform units. All these units tectonically lie on the buried Apulian platform which is covered, at least in the eastern sector of the chain, by Pliocene to Pleistocene foredeep deposits. Stratigraphic patterns of the Cretaceous to lower Miocene Lagonegro successions are coherent with the platform margin ones. Calcareous clastics of the Lagonegro basin are in fact supplied by an adjacent western platform, as inferred by several sedimentological evidences (slump and palaeocurrent directions and decreasing grain size towards the depocentre of the basin). Tectonic relationships among the different units of the chain — with particular emphasis on the Lagonegro and Apenninic platform units of the

  15. Towards Automated Structure-Based NMR Resonance Assignment

    NASA Astrophysics Data System (ADS)

    Jang, Richard; Gao, Xin; Li, Ming

    We propose a general framework for solving the structure-based NMR backbone resonance assignment problem. The core is a novel 0-1 integer programming model that can start from a complete or partial assignment, generate multiple assignments, and model not only the assignment of spins to residues, but also pairwise dependencies consisting of pairs of spins to pairs of residues. It is still a challenge for automated resonance assignment systems to perform the assignment directly from spectra without any manual intervention. To test the feasibility of this for structure-based assignment, we integrated our system with our automated peak picking and sequence-based resonance assignment system to obtain an assignment for the protein TM1112 with 91% recall and 99% precision without manual intervention. Since using a known structure has the potential to allow one to use only N-labeled NMR data and avoid the added expense of using C-labeled data, we work towards the goal of automated structure-based assignment using only such labeled data. Our system reduced the assignment error of Xiong-Pandurangan-Bailey-Kellogg's contact replacement (CR) method, which to our knowledge is the most error-tolerant method for this problem, by 5 folds on average. By using an iterative algorithm, our system has the added capability of using the NOESY data to correct assignment errors due to errors in predicting the amino acid and secondary structure type of each spin system. On a publicly available data set for Ubiquitin, where the type prediction accuracy is 83%, we achieved 91% assignment accuracy, compared to the 59% accuracy that was obtained without correcting for typing errors.

  16. Automated crystallographic system for high-throughput protein structure determination.

    PubMed

    Brunzelle, Joseph S; Shafaee, Padram; Yang, Xiaojing; Weigand, Steve; Ren, Zhong; Anderson, Wayne F

    2003-07-01

    High-throughput structural genomic efforts require software that is highly automated, distributive and requires minimal user intervention to determine protein structures. Preliminary experiments were set up to test whether automated scripts could utilize a minimum set of input parameters and produce a set of initial protein coordinates. From this starting point, a highly distributive system was developed that could determine macromolecular structures at a high throughput rate, warehouse and harvest the associated data. The system uses a web interface to obtain input data and display results. It utilizes a relational database to store the initial data needed to start the structure-determination process as well as generated data. A distributive program interface administers the crystallographic programs which determine protein structures. Using a test set of 19 protein targets, 79% were determined automatically.

  17. North American Commission on Stratigraphic Nomenclature Report 12 – Revision of article 37, lithodemic units, of the North American Stratigraphic Code

    USGS Publications Warehouse

    Easton, Robert M.; Edwards, Lucy E.; Orndorff, Randall C.; Duguet, Manuel; Ferrusquia-Villafranca, Ismael

    2017-01-01

    At the 71st Annual Meeting of the North American Commission on Stratigraphic Nomenclature, 26 September, 2016, in Denver, Colorado, the Commission voted unanimously to accept the revision of Article 37 of the North American Stratigraphic Code (North American Commission on Stratigraphic Nomenclature, 2005), printed below. It replaces all older versions of this Article. An application for this revision (Easton et al. 2015) was published in Stratigraphy more than one year prior to the meeting; thus, the vote on this application for revision follows Article 21 of the Code.

  18. Automating Structural Analysis of Spacecraft Vehicles

    NASA Technical Reports Server (NTRS)

    Hrinda, Glenn A.

    2004-01-01

    A major effort within NASA's vehicle analysis discipline has been to automate structural analysis and sizing optimization during conceptual design studies of advanced spacecraft. Traditional spacecraft structural sizing has involved detailed finite element analysis (FEA) requiring large degree-of-freedom (DOF) finite element models (FEM). Creation and analysis of these models can be time consuming and limit model size during conceptual designs. The goal is to find an optimal design that meets the mission requirements but produces the lightest structure. A structural sizing tool called HyperSizer has been successfully used in the conceptual design phase of a reusable launch vehicle and planetary exploration spacecraft. The program couples with FEA to enable system level performance assessments and weight predictions including design optimization of material selections and sizing of spacecraft members. The software's analysis capabilities are based on established aerospace structural methods for strength, stability and stiffness that produce adequately sized members and reliable structural weight estimates. The software also helps to identify potential structural deficiencies early in the conceptual design so changes can be made without wasted time. HyperSizer's automated analysis and sizing optimization increases productivity and brings standardization to a systems study. These benefits will be illustrated in examining two different types of conceptual spacecraft designed using the software. A hypersonic air breathing, single stage to orbit (SSTO), reusable launch vehicle (RLV) will be highlighted as well as an aeroshell for a planetary exploration vehicle used for aerocapture at Mars. By showing the two different types of vehicles, the software's flexibility will be demonstrated with an emphasis on reducing aeroshell structural weight. Member sizes, concepts and material selections will be discussed as well as analysis methods used in optimizing the structure

  19. Stratigraphic Architecture of Aeolian Dune Interactions

    NASA Astrophysics Data System (ADS)

    Brothers, S. C.; Kocurek, G.

    2015-12-01

    Dune interactions, which consist of collisions and detachments, are a known driver of changing dune morphology and provide the dynamics for field-scale patterning. Although interactions are ubiquitous in modern dune fields, the stratigraphic record of interactions has not been explored. This raises the possibility that an entire class of signature architectures of bounding surfaces and cross-strata has gone misidentified or unrecognized. A unique data set for the crescentic dunes of the White Sands Dune Field, New Mexico, allows for the coupling of dune interactions with their resultant stratigraphic architecture. Dune interactions are documented by a decadal time-series of aerial photos and LiDAR-derived digital elevation models. Plan-view cross-strata in interdune areas provide a record tying past dune positions and morphologies to the current dunes. Three-dimensional stratigraphic architecture is revealed by imaging of dune interiors with ground-penetrating radar. The architecture of a dune defect merging with a target dune downwind consists of lateral truncation of the target dune set by an interaction bounding surface. Defect cross-strata tangentially approach and downlap onto the surface. Downwind, the interaction surface curves, and defect and adjacent target dune sets merge into a continuous set. Predictable angular relationships reflect field-scale patterns of dune migration direction and approach angle of migrating defects. The discovery of interaction architectures emphasizes that although dunes appear as continuous forms on the surface, they consist of discrete segments, each with a distinct morphodynamic history. Bedform interactions result in the morphologic recombination of dune bodies, which is manifested stratigraphically within the sets of cross-strata.

  20. Integration of seismic-reflection and well data to assess the potential impact of stratigraphic and structural features on sustainable water supply from the Floridan aquifer system, Broward County, Florida

    USGS Publications Warehouse

    Cunningham, Kevin J.

    2014-01-01

    The U.S. Geological Survey and Broward County water managers commenced a 3.5-year cooperative study in July 2012 to refine the geologic and hydrogeologic framework of the Floridan aquifer system (FAS) in Broward County. A lack of advanced stratigraphic knowledge of the physical system and structural geologic anomalies (faults and fractures originating from tectonics and karst-collapse structures) within the FAS pose a risk to the sustainable management of the resource. The principal objective of the study is to better define the regional stratigraphic and structural setting of the FAS in Broward County. The objective will be achieved through the acquisition, processing, and interpretation of new seismic-reflection data along several canals in Broward County. The interpretation includes integration of the new seismic-reflection data with existing seismic-reflection profiles along Hillsboro Canal in Broward County and within northeast Miami-Dade County, as well as with data from nearby FAS wellbores. The scope of the study includes mapping the geologic, hydrogeologic, and seismic-reflection framework of the FAS, and identifying stratigraphic and structural characteristics that could either facilitate or preclude the sustainable use of the FAS as an alternate water supply or a treated effluent repository. In addition, the investigation offers an opportunity to: (1) improve existing groundwater flow models, (2) enhance the understanding of the sensitivity of the groundwater system to well-field development and upconing of saline fluids, and (3) support site selection for future FAS projects, such as Class I wells that would inject treated effluent into the deep Boulder Zone.

  1. Teaching with Stratigraphic Profiles

    ERIC Educational Resources Information Center

    Stefanich, Greg P.

    1974-01-01

    Presents two exercises modeled after the ice age puzzle described in the ESCP textbook, including formation of terminal moraines and kettle lakes and intersection of normal faults with gold-quartz veins. Indicates that the stratigraphic profiles are usable in teaching earth science, geography, general science, and topographic problems. (CC)

  2. Sedimentological indicators of paleoenvironments and siliciclastic stratigraphic sequences in some Miocene deposits of the Calvert Cliffs, southern Maryland

    USGS Publications Warehouse

    Shideler, G.L.

    1994-01-01

    Middle Miocene siliciclastic deposits comprising the Calvert Cliffs section at the Baltimore Gas and Electric Company's (BG&E) nuclear power plant site in southern Maryland were analyzed in terms of lithostratigraphy, sedimentary structures, and granulometric parameters, to interprete paleo-environments within a sequence-stratigraphic framework. In terms of sequence-stratigraphic models, the BG&E section can be interpreted as consisting of two genetic stratigraphic sequences (Galloway model), namely, a shelf sequence and an overlying deltaic sequence. Using the Exxon model, the section consists of two third-order (1-5 m.y. duration) depositional sequences. The stratigraphic sequences of the BG&E section reflect both relatively short-term eustatic transgressive events, as well as a long-term regressive trend with associated local deltation and coastal progradation. The regression probably signified a regional basinward shift of depocenters within the Salisbury embayment during Miocene time. -from Author

  3. Seismic model study of Patrick Draw field, Wyoming: a stratigraphic trap in the Upper Cretaceous Almond Formation

    USGS Publications Warehouse

    Anderson, Robert C.; Ryder, Robert T.

    1978-01-01

    The Patrick Draw field, located on the eastern flank of the Rock Springs uplift in the Washakie basin of southwestern Wyoming, was discovered in 1959 without the use of geophysical methods. The field is a classic example of a stratigraphic trap, where Upper Cretaceous porous sandstone units pinch out on a structural nose. Two-dimensional seismic modeling was used to construct the seismic waveform expressions of the Patrick Draw field, and to better understand how to explore for other 'Patrick Draw' fields. Interpretation of the model shows that the detection of the reservoir sand is very difficult, owing to a combination of acoustic contrasts and bed thickness. Because the model included other major stratigraphic units in the subsurface, several stratigraphic traps are suggested as potential exploration targets.

  4. Measuring Stratigraphic Congruence Across Trees, Higher Taxa, and Time

    PubMed Central

    O'Connor, Anne; Wills, Matthew A.

    2016-01-01

    The congruence between the order of cladistic branching and the first appearance dates of fossil lineages can be quantified using a variety of indices. Good matching is a prerequisite for the accurate time calibration of trees, while the distribution of congruence indices across large samples of cladograms has underpinned claims about temporal and taxonomic patterns of completeness in the fossil record. The most widely used stratigraphic congruence indices are the stratigraphic consistency index (SCI), the modified Manhattan stratigraphic measure (MSM*), and the gap excess ratio (GER) (plus its derivatives; the topological GER and the modified GER). Many factors are believed to variously bias these indices, with several empirical and simulation studies addressing some subset of the putative interactions. This study combines both approaches to quantify the effects (on all five indices) of eight variables reasoned to constrain the distribution of possible values (the number of taxa, tree balance, tree resolution, range of first occurrence (FO) dates, center of gravity of FO dates, the variability of FO dates, percentage of extant taxa, and percentage of taxa with no fossil record). Our empirical data set comprised 647 published animal and plant cladograms spanning the entire Phanerozoic, and for these data we also modeled the effects of mean age of FOs (as a proxy for clade age), the taxonomic rank of the clade, and the higher taxonomic group to which it belonged. The center of gravity of FO dates had not been investigated hitherto, and this was found to correlate most strongly with some measures of stratigraphic congruence in our empirical study (top-heavy clades had better congruence). The modified GER was the index least susceptible to bias. We found significant differences across higher taxa for all indices; arthropods had lower congruence and tetrapods higher congruence. Stratigraphic congruence—however measured—also varied throughout the Phanerozoic

  5. Glaciotectonic deformation and reinterpretation of the Worth Point stratigraphic sequence: Banks Island, NT, Canada

    NASA Astrophysics Data System (ADS)

    Vaughan, Jessica M.; England, John H.; Evans, David J. A.

    2014-05-01

    Hill-hole pairs, comprising an ice-pushed hill and associated source depression, cluster in a belt along the west coast of Banks Island, NT. Ongoing coastal erosion at Worth Point, southwest Banks Island, has exposed a section (6 km long and ˜30 m high) through an ice-pushed hill that was transported ˜ 2 km from a corresponding source depression to the southeast. The exposed stratigraphic sequence is polydeformed and comprises folded and faulted rafts of Early Cretaceous and Late Tertiary bedrock, a prominent organic raft, Quaternary glacial sediments, and buried glacial ice. Three distinct structural domains can be identified within the stratigraphic sequence that represent proximal to distal deformation in an ice-marginal setting. Complex thrust sequences, interfering fold-sets, brecciated bedrock and widespread shear structures superimposed on this ice-marginally deformed sequence record subsequent deformation in a subglacial shear zone. Analysis of cross-cutting relationships within the stratigraphic sequence combined with OSL dating indicate that the Worth Point hill-hole pair was deformed during two separate glaciotectonic events. Firstly, ice sheet advance constructed the hill-hole pair and glaciotectonized the strata ice-marginally, producing a proximal to distal deformation sequence. A glacioisostatically forced marine transgression resulted in extensive reworking of the strata and the deposition of a glaciomarine diamict. A readvance during this initial stage redeformed the strata in a subglacial shear zone, overprinting complex deformation structures and depositing a glaciotectonite ˜20 m thick. Outwash channels that incise the subglacially deformed strata record a deglacial marine regression, whereas aggradation of glaciofluvial sand and gravel infilling the channels record a subsequent marine transgression. Secondly, a later, largely non-erosive ice margin overrode Worth Point, deforming only the most surficial units in the section and depositing a

  6. 12 CFR Appendix D to Part 360 - Sweep/Automated Credit Account File Structure

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .../Automated Credit Account File Structure This is the structure of the data file to provide information to the... remainder of the data fields defined below should be populated. For data provided in the Sweep/Automated... number. The Account Identifier may be composed of more than one physical data element. If multiple fields...

  7. 12 CFR Appendix D to Part 360 - Sweep/Automated Credit Account File Structure

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .../Automated Credit Account File Structure This is the structure of the data file to provide information to the... remainder of the data fields defined below should be populated. For data provided in the Sweep/Automated... number. The Account Identifier may be composed of more than one physical data element. If multiple fields...

  8. 12 CFR Appendix D to Part 360 - Sweep/Automated Credit Account File Structure

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .../Automated Credit Account File Structure This is the structure of the data file to provide information to the... remainder of the data fields defined below should be populated. For data provided in the Sweep/Automated... number. The Account Identifier may be composed of more than one physical data element. If multiple fields...

  9. 12 CFR Appendix D to Part 360 - Sweep/Automated Credit Account File Structure

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .../Automated Credit Account File Structure This is the structure of the data file to provide information to the... remainder of the data fields defined below should be populated. For data provided in the Sweep/Automated... number. The Account Identifier may be composed of more than one physical data element. If multiple fields...

  10. The stratigraphic filter and bias in measurement of geologic rates

    USGS Publications Warehouse

    Schumer, Rina; Jerolmack, Douglas; McElroy, Brandon

    2011-01-01

    Erosion and deposition rates estimated from the stratigraphic record frequently exhibit a power-law dependence on measurement interval. This dependence can result from a power-law distribution of stratigraphic hiatuses. By representing the stratigraphic filter as a stochastic process called a reverse ascending ladder, we describe a likely origin of power-law hiatuses, and thus, rate scaling. While power-law hiatuses in certain environments can be a direct result of power-law periods of stasis (no deposition or erosion), they are more generally the result of randomness in surface fluctuations irrespective of mean subsidence or uplift. Autocorrelation in fluctuations can make hiatuses more or less heavy-tailed, but still exhibit power-law characteristics. In addition we show that by passing stratigraphic data backward through the filter, certain statistics of surface kinematics from their formative environments can be inferred.

  11. A robust automated system elucidates mouse home cage behavioral structure

    PubMed Central

    Goulding, Evan H.; Schenk, A. Katrin; Juneja, Punita; MacKay, Adrienne W.; Wade, Jennifer M.; Tecott, Laurence H.

    2008-01-01

    Patterns of behavior exhibited by mice in their home cages reflect the function and interaction of numerous behavioral and physiological systems. Detailed assessment of these patterns thus has the potential to provide a powerful tool for understanding basic aspects of behavioral regulation and their perturbation by disease processes. However, the capacity to identify and examine these patterns in terms of their discrete levels of organization across diverse behaviors has been difficult to achieve and automate. Here, we describe an automated approach for the quantitative characterization of fundamental behavioral elements and their patterns in the freely behaving mouse. We demonstrate the utility of this approach by identifying unique features of home cage behavioral structure and changes in distinct levels of behavioral organization in mice with single gene mutations altering energy balance. The robust, automated, reproducible quantification of mouse home cage behavioral structure detailed here should have wide applicability for the study of mammalian physiology, behavior, and disease. PMID:19106295

  12. Measuring Stratigraphic Congruence Across Trees, Higher Taxa, and Time.

    PubMed

    O'Connor, Anne; Wills, Matthew A

    2016-09-01

    The congruence between the order of cladistic branching and the first appearance dates of fossil lineages can be quantified using a variety of indices. Good matching is a prerequisite for the accurate time calibration of trees, while the distribution of congruence indices across large samples of cladograms has underpinned claims about temporal and taxonomic patterns of completeness in the fossil record. The most widely used stratigraphic congruence indices are the stratigraphic consistency index (SCI), the modified Manhattan stratigraphic measure (MSM*), and the gap excess ratio (GER) (plus its derivatives; the topological GER and the modified GER). Many factors are believed to variously bias these indices, with several empirical and simulation studies addressing some subset of the putative interactions. This study combines both approaches to quantify the effects (on all five indices) of eight variables reasoned to constrain the distribution of possible values (the number of taxa, tree balance, tree resolution, range of first occurrence (FO) dates, center of gravity of FO dates, the variability of FO dates, percentage of extant taxa, and percentage of taxa with no fossil record). Our empirical data set comprised 647 published animal and plant cladograms spanning the entire Phanerozoic, and for these data we also modeled the effects of mean age of FOs (as a proxy for clade age), the taxonomic rank of the clade, and the higher taxonomic group to which it belonged. The center of gravity of FO dates had not been investigated hitherto, and this was found to correlate most strongly with some measures of stratigraphic congruence in our empirical study (top-heavy clades had better congruence). The modified GER was the index least susceptible to bias. We found significant differences across higher taxa for all indices; arthropods had lower congruence and tetrapods higher congruence. Stratigraphic congruence-however measured-also varied throughout the Phanerozoic, reflecting

  13. The stratigraphic filter and bias in measurement of geologic rates

    USGS Publications Warehouse

    Schumer, R.; Jerolmack, D.; McElroy, B.

    2011-01-01

    Erosion and deposition rates estimated from the stratigraphic record frequently exhibit a power-law dependence on measurement interval. This dependence can result from a power-law distribution of stratigraphic hiatuses. By representing the stratigraphic filter as a stochastic process called a reverse ascending ladder, we describe a likely origin of power-law hiatuses, and thus, rate scaling. While power-law hiatuses in certain environments can be a direct result of power-law periods of stasis (no deposition or erosion), they are more generally the result of randomness in surface fluctuations irrespective of mean subsidence or uplift. Autocorrelation in fluctuations can make hiatuses more or less heavy-tailed, but still exhibit power-law characteristics. In addition we show that by passing stratigraphic data backward through the filter, certain statistics of surface kinematics from their formative environments can be inferred. Copyright ?? 2011 by the American Geophysical Union.

  14. Stratigraphic Signatures of Forearc Basin Formation Mechanisms

    NASA Astrophysics Data System (ADS)

    Mannu, U.; Ueda, K.; Gerya, T.; Willett, S.; Strasser, M.

    2014-12-01

    Forearc basins are loci of active sedimentation above the landward portion of accretionary prisms. Although these basins typically remain separated from the frontal prism by a forearc high, their evolution has a significant impact on the structure and deformation of the entire wedge. Formation of forearc basins has been proposed as a consequence of changes in wedge stability due to an increase of slab dip in subduction zones. Another hypothesis attributes this to higher hinterland sedimentation, which causes the rear of the wedge to stabilize and eventually develop a forearc basin. Basin stratigraphic architecture, revealed by high-resolution reflection seismic data and borehole data allows interpretation of structural development of the accretionary prism and associated basins with the goal of determining the underlying driving mechanism(s) of basin formation. In this study we supplement data interpretation with thermo-mechanical numerical models including high-resolution isochronal surface tracking to visualize the developing stratigraphy of basins that develop in subduction zone and wedge dynamic models. We use a dynamic 2D thermo mechanical model incorporating surface processes, strain weakening and sediment subduction. The model is a modification of I2VIS model, which is based on conservative, fully staggered finite differences and a non-diffusive marker- in-cell technique capable of modelling mantle convection. In the model different driving mechanisms for basin formation can be explored. Stratigraphic simulations obtained by isochronal surface tracking are compared to reflection pattern and stratigraphy of seismic and borehole data, respectively. Initial results from a model roughly representing the Nankai Trough Subduction Zone offshore Japan are compared to available seismic and Integrated Ocean Drilling (IODP) data. A calibrated model predicting forearc basin stratigraphy will be used to discern the underlying process of basins formation and wedge

  15. Automated segmentation of midbrain structures with high iron content.

    PubMed

    Garzón, Benjamín; Sitnikov, Rouslan; Bäckman, Lars; Kalpouzos, Grégoria

    2018-04-15

    The substantia nigra (SN), the subthalamic nucleus (STN), and the red nucleus (RN) are midbrain structures of ample interest in many neuroimaging studies, which may benefit from the availability of automated segmentation methods. The high iron content of these structures awards them high contrast in quantitative susceptibility mapping (QSM) images. We present a novel segmentation method that leverages the information of these images to produce automated segmentations of the SN, STN, and RN. The algorithm builds a map of spatial priors for the structures by non-linearly registering a set of manually-traced training labels to the midbrain. The priors are used to inform a Gaussian mixture model of the image intensities, with smoothness constraints imposed to ensure anatomical plausibility. The method was validated on manual segmentations from a sample of 40 healthy younger and older subjects. Average Dice scores were 0.81 (0.05) for the SN, 0.66 (0.14) for the STN and 0.88 (0.04) for the RN in the left hemisphere, and similar values were obtained for the right hemisphere. In all structures, volumes of manual and automatically obtained segmentations were significantly correlated. The algorithm showed lower accuracy on R 2 * and T 2 -weighted Fluid Attenuated Inversion Recovery (FLAIR) images, which are also sensitive to iron content. To illustrate an application of the method, we show that the automated segmentations were comparable to the manual ones regarding detection of age-related differences to putative iron content. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Automated and fast building of three-dimensional RNA structures.

    PubMed

    Zhao, Yunjie; Huang, Yangyu; Gong, Zhou; Wang, Yanjie; Man, Jianfen; Xiao, Yi

    2012-01-01

    Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program, 3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology.

  17. Automated structural classification of lipids by machine learning.

    PubMed

    Taylor, Ryan; Miller, Ryan H; Miller, Ryan D; Porter, Michael; Dalgleish, James; Prince, John T

    2015-03-01

    Modern lipidomics is largely dependent upon structural ontologies because of the great diversity exhibited in the lipidome, but no automated lipid classification exists to facilitate this partitioning. The size of the putative lipidome far exceeds the number currently classified, despite a decade of work. Automated classification would benefit ongoing classification efforts by decreasing the time needed and increasing the accuracy of classification while providing classifications for mass spectral identification algorithms. We introduce a tool that automates classification into the LIPID MAPS ontology of known lipids with >95% accuracy and novel lipids with 63% accuracy. The classification is based upon simple chemical characteristics and modern machine learning algorithms. The decision trees produced are intelligible and can be used to clarify implicit assumptions about the current LIPID MAPS classification scheme. These characteristics and decision trees are made available to facilitate alternative implementations. We also discovered many hundreds of lipids that are currently misclassified in the LIPID MAPS database, strongly underscoring the need for automated classification. Source code and chemical characteristic lists as SMARTS search strings are available under an open-source license at https://www.github.com/princelab/lipid_classifier. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  18. Petroleum system elements within the Late Cretaceous and Early Paleogene sediments of Nigeria's inland basins: An integrated sequence stratigraphic approach

    NASA Astrophysics Data System (ADS)

    Dim, Chidozie Izuchukwu Princeton; Onuoha, K. Mosto; Okeugo, Chukwudike Gabriel; Ozumba, Bertram Maduka

    2017-06-01

    Sequence stratigraphic studies have been carried out using subsurface well and 2D seismic data in the Late Cretaceous and Early Paleogene sediments of Anambra and proximal onshore section of Niger Delta Basin in the Southeastern Nigeria. The aim was to establish the stratigraphic framework for better understanding of the reservoir, source and seal rock presence and distribution in the basin. Thirteen stratigraphic bounding surfaces (consisting of six maximum flooding surfaces - MFSs and seven sequence boundaries - SBs) were recognized and calibrated using a newly modified chronostratigraphic chart. Stratigraphic surfaces were matched with corresponding foraminiferal and palynological biozones, aiding correlation across wells in this study. Well log sequence stratigraphic correlation reveals that stratal packages within the basin are segmented into six depositional sequences occurring from Late Cretaceous to Early Paleogene age. Generated gross depositional environment maps at various MFSs show that sediment packages deposited within shelfal to deep marine settings, reflect continuous rise and fall of sea levels within a regressive cycle. Each of these sequences consist of three system tracts (lowstand system tract - LST, transgressive system tract - TST and highstand system tract - HST) that are associated with mainly progradational and retrogradational sediment stacking patterns. Well correlation reveals that the sand and shale units of the LSTs, HSTs and TSTs, that constitute the reservoir and source/seal packages respectively are laterally continuous and thicken basinwards, due to structural influences. Result from interpretation of seismic section reveals the presence of hanging wall, footwall, horst block and collapsed crest structures. These structural features generally aid migration and offer entrapment mechanism for hydrocarbon accumulation. The combination of these reservoirs, sources, seals and trap elements form a good petroleum system that is viable

  19. Integration of the stratigraphic aspects of very large sea-floor databases using information processing

    USGS Publications Warehouse

    Jenkins, Clinton N.; Flocks, J.; Kulp, M.; ,

    2006-01-01

    Information-processing methods are described that integrate the stratigraphic aspects of large and diverse collections of sea-floor sample data. They efficiently convert common types of sea-floor data into database and GIS (geographical information system) tables, visual core logs, stratigraphic fence diagrams and sophisticated stratigraphic statistics. The input data are held in structured documents, essentially written core logs that are particularly efficient to create from raw input datasets. Techniques are described that permit efficient construction of regional databases consisting of hundreds of cores. The sedimentological observations in each core are located by their downhole depths (metres below sea floor - mbsf) and also by a verbal term that describes the sample 'situation' - a special fraction of the sediment or position in the core. The main processing creates a separate output event for each instance of top, bottom and situation, assigning top-base mbsf values from numeric or, where possible, from word-based relative locational information such as 'core catcher' in reference to sampler device, and recovery or penetration length. The processing outputs represent the sub-bottom as a sparse matrix of over 20 sediment properties of interest, such as grain size, porosity and colour. They can be plotted in a range of core-log programs including an in-built facility that better suits the requirements of sea-floor data. Finally, a suite of stratigraphic statistics are computed, including volumetric grades, overburdens, thicknesses and degrees of layering. ?? The Geological Society of London 2006.

  20. Towards fully automated structure-based function prediction in structural genomics: a case study.

    PubMed

    Watson, James D; Sanderson, Steve; Ezersky, Alexandra; Savchenko, Alexei; Edwards, Aled; Orengo, Christine; Joachimiak, Andrzej; Laskowski, Roman A; Thornton, Janet M

    2007-04-13

    As the global Structural Genomics projects have picked up pace, the number of structures annotated in the Protein Data Bank as hypothetical protein or unknown function has grown significantly. A major challenge now involves the development of computational methods to assign functions to these proteins accurately and automatically. As part of the Midwest Center for Structural Genomics (MCSG) we have developed a fully automated functional analysis server, ProFunc, which performs a battery of analyses on a submitted structure. The analyses combine a number of sequence-based and structure-based methods to identify functional clues. After the first stage of the Protein Structure Initiative (PSI), we review the success of the pipeline and the importance of structure-based function prediction. As a dataset, we have chosen all structures solved by the MCSG during the 5 years of the first PSI. Our analysis suggests that two of the structure-based methods are particularly successful and provide examples of local similarity that is difficult to identify using current sequence-based methods. No one method is successful in all cases, so, through the use of a number of complementary sequence and structural approaches, the ProFunc server increases the chances that at least one method will find a significant hit that can help elucidate function. Manual assessment of the results is a time-consuming process and subject to individual interpretation and human error. We present a method based on the Gene Ontology (GO) schema using GO-slims that can allow the automated assessment of hits with a success rate approaching that of expert manual assessment.

  1. Automated structure determination of proteins with the SAIL-FLYA NMR method.

    PubMed

    Takeda, Mitsuhiro; Ikeya, Teppei; Güntert, Peter; Kainosho, Masatsune

    2007-01-01

    The labeling of proteins with stable isotopes enhances the NMR method for the determination of 3D protein structures in solution. Stereo-array isotope labeling (SAIL) provides an optimal stereospecific and regiospecific pattern of stable isotopes that yields sharpened lines, spectral simplification without loss of information, and the ability to collect rapidly and evaluate fully automatically the structural restraints required to solve a high-quality solution structure for proteins up to twice as large as those that can be analyzed using conventional methods. Here, we describe a protocol for the preparation of SAIL proteins by cell-free methods, including the preparation of S30 extract and their automated structure analysis using the FLYA algorithm and the program CYANA. Once efficient cell-free expression of the unlabeled or uniformly labeled target protein has been achieved, the NMR sample preparation of a SAIL protein can be accomplished in 3 d. A fully automated FLYA structure calculation can be completed in 1 d on a powerful computer system.

  2. Fossils out of sequence: Computer simulations and strategies for dealing with stratigraphic disorder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cutler, A.H.; Flessa, K.W.

    Microstratigraphic resolution is limited by vertical mixing and reworking of fossils. Stratigraphic disorder is the degree to which fossils within a stratigraphic sequence are not in proper chronological order. Stratigraphic disorder arises through in situ vertical mixing of fossils and reworking of older fossils into younger deposits. The authors simulated the effects of mixing and reworking by simple computer models, and measured stratigraphic disorder using rank correlation between age and stratigraphic position (Spearman and Kendall coefficients). Mixing was simulated by randomly transposing pairs of adjacent fossils in a sequence. Reworking was simulated by randomly inserting older fossils into a youngermore » sequence. Mixing is an inefficient means of producing disorder; after 500 mixing steps stratigraphic order is still significant at the 99% to 95% level, depending on the coefficient used. Reworking disorders sequences very efficiently: significant order begins to be lost when reworked shells make up 35% of the sequence. Thus a sequence can be dominated by undisturbed, autochthonous shells and still be disordered. The effects of mixing-produced disorder can be minimized by increasing sample size at each horizon. Increased spacing between samples is of limited utility in dealing with disordered sequences: while widely separated samples are more likely to be stratigraphically ordered, the smaller number of samples makes the detection of trends problematic.« less

  3. Stratigraphic Units in Las Vegas Valley, Nevada

    NASA Astrophysics Data System (ADS)

    Donovan, D.

    2013-12-01

    Using 25 well logs, 15 of which also had accompanying geophysical and aquifer test data were used to describe and establish three alloformations including the Tule Spring and Paradise Valley Alloformations and four aquiformations, the most well defined being, the Las Vegas Springs Aquiformation, in the west central part of the bolson (Donovan, 1996), primarily in Township 20 South, Range 60 East, Mount Diablo Baseline and Meridian (MDBLM), with the stratotypes designated in T20S, R61E S31 MDBLM (36° 9'59.89"N 115°11'26.34"W). The allostratigraphic units were developed using the recommendations in the North American Code of Stratigraphic Nomenclature (NACSN, 1983 and 2005). The hydrostratigraphic units were developed following the recommendations of Seaber (1992). The units constitute the bulk of the upper 500 meter section. Twenty additional wells in the same geographic area, drilled and completed between 1995 and 2005 with detailed geologic and hydrologic information provided confirmation of these units. The proposed stratigraphic units are not part of either, and are located between, the two previously named and non-contiguous formations in the bolson (the Miocene Muddy Creek Formation and the late Pleistocene Las Vegas Formation) (Longwell et al 1965). Las Vegas Valley contains a metropolitan area of approximately two million people. The deeper part of the alluvial basin below 300 ft below ground surface is of interest for supply and storage. The shallower part is of interest for water quality and the interaction between the ground water system and engineered structures.

  4. Stratigraphic framework for Pliocene paleoclimate reconstruction: The correlation conundrum

    USGS Publications Warehouse

    Dowsett, H.J.; Robinson, M.M.

    2006-01-01

    Pre-Holocene paleoclimate reconstructions face a correlation conundrum because complications inherent in the stratigraphic record impede the development of synchronous reconstruction. The Pliocene Research, Interpretation and Synoptic Mapping (PRISM) paleoenvironmental reconstructions have carefully balanced temporal resolution and paleoclimate proxy data to achieve a useful and reliable product and are the most comprehensive pre-Pleistocene data sets available for analysis of warmer-than-present climate and for climate modeling experiments. This paper documents the stratigraphic framework for the mid-Pliocene sea surface temperature (SST) reconstruction of the North Atlantic and explores the relationship between stratigraphic/temporal resolution and various paleoceanographic estimates of SST. The magnetobiostratigraphic framework for the PRISM North Atlantic region is constructed from planktic foraminifer, calcareous nannofossil and paleomagnetic reversal events recorded in deep-sea cores and calibrated to age. Planktic foraminifer census data from multiple samples within the mid-Pliocene yield multiple SST estimates for each site. Extracting a single SST value at each site from multiple estimates, given the limitations of the material and stratigraphic resolution, is problematic but necessary for climate model experiments. The PRISM reconstruction, unprecedented in its integration of many different types of data at a focused stratigraphic interval, utilizes a time slab approach and is based on warm peak average temperatures. A greater understanding of the dynamics of the climate system and significant advances in models now mandate more precise, globally distributed yet temporally synchronous SST estimates than are available through averaging techniques. Regardless of the precision used to correlate between sequences within the midd-Pliocene, a truly synoptic reconstruction in the temporal sense is unlikely. SST estimates from multiple proxies promise to further

  5. Stratigraphic Transfer Thresholds of Sediment Supply Signals in Channelized Systems

    NASA Astrophysics Data System (ADS)

    Toby, S. C.; De Angelis, S.; Duller, R.; Straub, K. M.

    2016-12-01

    The stratigraphic record is a unique physical archive for past climate and tectonic boundary conditions on Earth and other planetary bodies. These boundary and forcing conditions set the rate and volume of sediment delivered to sedimentary basins, which can be, theoretically, linked back to the stratigraphic record. However for sediment supply signals to make their way through to stratigraphy they must pass through the active layer of the Earth's surface, which is scaled to channel depth. For the long-term, the likelihood of this taking place can be evaluated using the vertical time-scale of autogenics. The current study tests whether or not cyclic sediment supply to an experimental delta can influence morphodynamics and if so, can this be recovered from synthetic and physical stratigraphic dataset collected during the experiments. Preliminary results suggest that short period sediment supply signals are less likely to be transferred to the stratigraphic record, which is predicted by our theoretical framework for channelized systems. Once fully validated by the experiments the theoretical approach will be applied to field stratigraphy and used to guide more reliable interpretation of ancient sediment supply signals.

  6. The geostatistical approach for structural and stratigraphic framework analysis of offshore NW Bonaparte Basin, Australia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wahid, Ali, E-mail: ali.wahid@live.com; Salim, Ahmed Mohamed Ahmed, E-mail: mohamed.salim@petronas.com.my; Yusoff, Wan Ismail Wan, E-mail: wanismail-wanyusoff@petronas.com.my

    2016-02-01

    Geostatistics or statistical approach is based on the studies of temporal and spatial trend, which depend upon spatial relationships to model known information of variable(s) at unsampled locations. The statistical technique known as kriging was used for petrophycial and facies analysis, which help to assume spatial relationship to model the geological continuity between the known data and the unknown to produce a single best guess of the unknown. Kriging is also known as optimal interpolation technique, which facilitate to generate best linear unbiased estimation of each horizon. The idea is to construct a numerical model of the lithofacies and rockmore » properties that honor available data and further integrate with interpreting seismic sections, techtonostratigraphy chart with sea level curve (short term) and regional tectonics of the study area to find the structural and stratigraphic growth history of the NW Bonaparte Basin. By using kriging technique the models were built which help to estimate different parameters like horizons, facies, and porosities in the study area. The variograms were used to determine for identification of spatial relationship between data which help to find the depositional history of the North West (NW) Bonaparte Basin.« less

  7. Mechanical Alteration And Contamination Issues In Automated Subsurface Sample Acquisition And Handling

    NASA Astrophysics Data System (ADS)

    Glass, B. J.; Cannon, H.; Bonaccorsi, R.; Zacny, K.

    2006-12-01

    order to obtain cores and ice profiles at the drilling site. In the course of DAME drilling automation testing, the drilling-induced temperature gradients and their effects on encountered subsurface permafrost and ice layers were observed while drilling in frozen impact breccia at Haughton Crater. In repeated tests of robotic core removal processing and handling in the MARTE project, including field tests, cross-contamination issues arose between successive cores and samples, and procedures and metrics were developed for minimizing the cross-contamination. The MARTE core processing cross-contamination aspects were tested by analyzing a set of pristine samples (those stratigraphically known) vs. cuttings (loose clays) or artifacts from the robotic drilling (indurated clay layers). MARTE ground truth drilling, in parallel with the automated tests, provided control information on the discontinuity/continuity of the stratigraphic record (i.e., texture, color and structure of loose and consolidated materials).

  8. Automated sizing of large structures by mixed optimization methods

    NASA Technical Reports Server (NTRS)

    Sobieszczanski, J.; Loendorf, D.

    1973-01-01

    A procedure for automating the sizing of wing-fuselage airframes was developed and implemented in the form of an operational program. The program combines fully stressed design to determine an overall material distribution with mass-strength and mathematical programming methods to design structural details accounting for realistic design constraints. The practicality and efficiency of the procedure is demonstrated for transport aircraft configurations. The methodology is sufficiently general to be applicable to other large and complex structures.

  9. Non-Uniform Sampling and J-UNIO Automation for Efficient Protein NMR Structure Determination.

    PubMed

    Didenko, Tatiana; Proudfoot, Andrew; Dutta, Samit Kumar; Serrano, Pedro; Wüthrich, Kurt

    2015-08-24

    High-resolution structure determination of small proteins in solution is one of the big assets of NMR spectroscopy in structural biology. Improvements in the efficiency of NMR structure determination by advances in NMR experiments and automation of data handling therefore attracts continued interest. Here, non-uniform sampling (NUS) of 3D heteronuclear-resolved [(1)H,(1)H]-NOESY data yielded two- to three-fold savings of instrument time for structure determinations of soluble proteins. With the 152-residue protein NP_372339.1 from Staphylococcus aureus and the 71-residue protein NP_346341.1 from Streptococcus pneumonia we show that high-quality structures can be obtained with NUS NMR data, which are equally well amenable to robust automated analysis as the corresponding uniformly sampled data. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

    PubMed Central

    Haas, Brian J; Salzberg, Steven L; Zhu, Wei; Pertea, Mihaela; Allen, Jonathan E; Orvis, Joshua; White, Owen; Buell, C Robin; Wortman, Jennifer R

    2008-01-01

    EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program to Assemble Spliced Alignments (PASA), yields a comprehensive, configurable annotation system that predicts protein-coding genes and alternatively spliced isoforms. Our experiments on both rice and human genome sequences demonstrate that EVM produces automated gene structure annotation approaching the quality of manual curation. PMID:18190707

  11. Automated Fault Interpretation and Extraction using Improved Supplementary Seismic Datasets

    NASA Astrophysics Data System (ADS)

    Bollmann, T. A.; Shank, R.

    2017-12-01

    During the interpretation of seismic volumes, it is necessary to interpret faults along with horizons of interest. With the improvement of technology, the interpretation of faults can be expedited with the aid of different algorithms that create supplementary seismic attributes, such as semblance and coherency. These products highlight discontinuities, but still need a large amount of human interaction to interpret faults and are plagued by noise and stratigraphic discontinuities. Hale (2013) presents a method to improve on these datasets by creating what is referred to as a Fault Likelihood volume. In general, these volumes contain less noise and do not emphasize stratigraphic features. Instead, planar features within a specified strike and dip range are highlighted. Once a satisfactory Fault Likelihood Volume is created, extraction of fault surfaces is much easier. The extracted fault surfaces are then exported to interpretation software for QC. Numerous software packages have implemented this methodology with varying results. After investigating these platforms, we developed a preferred Automated Fault Interpretation workflow.

  12. Digital tabulation of stratigraphic data from oil and gas wells in Cuyama Valley and surrounding areas, central California

    USGS Publications Warehouse

    Sweetkind, Donald S.; Bova, Shiera C.; Langenheim, V.E.; Shumaker, Lauren E.; Scheirer, Daniel S.

    2013-01-01

    Stratigraphic information from 391 oil and gas exploration wells from Cuyama Valley, California, and surrounding areas are herein compiled in digital form from reports that were released originally in paper form. The Cuyama Basin is located within the southeasternmost part of the Coast Ranges and north of the western Transverse Ranges, west of the San Andreas fault. Knowledge of the location and elevation of stratigraphic tops of formations throughout the basin is a first step toward understanding depositional trends and the structural evolution of the basin through time, and helps in understanding the slip history and partitioning of slip on San Andreas and related faults.

  13. Vombat: an open source proof-of-concept for the use of Digital outcrop models as reference frame for stratigraphic observations

    NASA Astrophysics Data System (ADS)

    Penasa, Luca; Franceschi, Marco; Preto, Nereo; Girardeau-Montaut, Daniel

    2015-04-01

    Three-dimensional Virtual Outcrop Models (VOMs), often produced using terrestrial laser scanning or photogrammetry, have become popular in the Geosciences. The main feature of a VOM is that it allows for a quantification of the 3D geometry and/or distribution of geologic features that range from rock properties to structural elements. This actually generated much of the interest in VOMs by the oil and gas industry. The potential importance of a VOM in stratigraphy, however, does not seems completely disclosed yet. Indeed outcrops are the primary sources of data for a number of stratigraphic studies (e.g. palaeontology, sedimentology, cyclostratigraphy, geochemistry...). All the observations are typically reported on stratigraphic logs which constitute an idealized representation of the stratigraphic series, drawn by the researcher on the basis of the features that has to be highlighted. The observations are localized by means of manual measurements and a certain amount of subjectivity in log drawing is involved. These facts can prevent the log from being properly pinned to the real outcrop. Moreover, the integration of stratigraphic logs made by different researchers studying the same outcrop may be difficult. The exposure conditions of outcrops can change through time, to the point that they can become unaccessible or even be destroyed. In such a case, linking the stratigraphic log to its physical counterpart becomes impossible. This can be particularly relevant when a classical outcrop or even a GSSP is considered. A VOM may prove useful to tackle these issues, by providing a more objective stratigraphic reference for measurements and by preserving an outcrop through time as a visual representation, thus permitting reference and accurate comparison between observations made through time. Finally, a VOM itself may contain relevant stratigraphic information (e.g. scalar fields associated with the point cloud as intensity, rgb data or hyperspectral information from

  14. Triassic-Jurassic sediments and multiple volcanic events in North Victoria Land, Antarctica: A revised stratigraphic model

    USGS Publications Warehouse

    Schöner, R.; Viereck-Goette, L.; Schneider, J.; Bomfleur, B.

    2007-01-01

    Field investigations in North Victoria Land, Antarctica during GANOVEX IX (2005/2006) allow the revision of the Triassic-Jurassic stratigraphy of ~300 m thick continental deposits in between the crystalline basement and the Kirkpatrick lava flows of the Ferrar Group. The lower stratigraphic unit (Section Peak Formation) is characterised by braided river-type quartzose sandstone deposits with intercalations of shale and coal occurring at the top. It is overlain by a homogeneous unit of reworked tuffs composed of fine-grained silicic shards, quartz and feldspar (new name: "Shafer Peak Formation"). These deposits can be correlated with parts of the Hanson Formation in the Central Transantarctic Mountains and require a distal yet unknown source of massive silicic volcanism. Clastic products of mafic volcanic eruptions, formerly described as a separate stratigraphic formation (Exposure Hill Formation), occur within local diatreme structures as well as intercalated at various stratigraphic levels within the sedimentary succession. These dominantly hydroclastic eruptions are the first subaerial expression of Ferrar magmatism. The initial Kirkpatrick lavas/pillow lavas were generated from local eruptive centres and again may be overlain by thin sediments, which are covered by the thick plateau lava succession known throughout the Transantarctic Mountain Range.

  15. Automated Assignment of MS/MS Cleavable Cross-Links in Protein 3D-Structure Analysis

    NASA Astrophysics Data System (ADS)

    Götze, Michael; Pettelkau, Jens; Fritzsche, Romy; Ihling, Christian H.; Schäfer, Mathias; Sinz, Andrea

    2015-01-01

    CID-MS/MS cleavable cross-linkers hold an enormous potential for an automated analysis of cross-linked products, which is essential for conducting structural proteomics studies. The created characteristic fragment ion patterns can easily be used for an automated assignment and discrimination of cross-linked products. To date, there are only a few software solutions available that make use of these properties, but none allows for an automated analysis of cleavable cross-linked products. The MeroX software fills this gap and presents a powerful tool for protein 3D-structure analysis in combination with MS/MS cleavable cross-linkers. We show that MeroX allows an automatic screening of characteristic fragment ions, considering static and variable peptide modifications, and effectively scores different types of cross-links. No manual input is required for a correct assignment of cross-links and false discovery rates are calculated. The self-explanatory graphical user interface of MeroX provides easy access for an automated cross-link search platform that is compatible with commonly used data file formats, enabling analysis of data originating from different instruments. The combination of an MS/MS cleavable cross-linker with a dedicated software tool for data analysis provides an automated workflow for 3D-structure analysis of proteins. MeroX is available at www.StavroX.com .

  16. A Highly Flexible, Automated System Providing Reliable Sample Preparation in Element- and Structure-Specific Measurements.

    PubMed

    Vorberg, Ellen; Fleischer, Heidi; Junginger, Steffen; Liu, Hui; Stoll, Norbert; Thurow, Kerstin

    2016-10-01

    Life science areas require specific sample pretreatment to increase the concentration of the analytes and/or to convert the analytes into an appropriate form for the detection and separation systems. Various workstations are commercially available, allowing for automated biological sample pretreatment. Nevertheless, due to the required temperature, pressure, and volume conditions in typical element and structure-specific measurements, automated platforms are not suitable for analytical processes. Thus, the purpose of the presented investigation was the design, realization, and evaluation of an automated system ensuring high-precision sample preparation for a variety of analytical measurements. The developed system has to enable system adaption and high performance flexibility. Furthermore, the system has to be capable of dealing with the wide range of required vessels simultaneously, allowing for less cost and time-consuming process steps. However, the system's functionality has been confirmed in various validation sequences. Using element-specific measurements, the automated system was up to 25% more precise compared to the manual procedure and as precise as the manual procedure using structure-specific measurements. © 2015 Society for Laboratory Automation and Screening.

  17. The Stratigraphic Incompleteness of Submarine Channels

    NASA Astrophysics Data System (ADS)

    Vendettuoli, D.; Clare, M. A.; Hughes Clarke, J. E.; Cartigny, M.; Vellinga, A. J.; Talling, P.; Hizzett, J. L.; Hage, S.; Waltham, D.; Hubbard, S. M.

    2017-12-01

    Turbidity currents transport prodigious quantities of sediment across the world's oceans through submarine channels. These flows damage strategically important seafloor infrastructure and their deposits host major oil and gas reservoirs. We therefore need to understand these flows, but their very powerful nature makes direct monitoring challenging. Most studies to date focus on the deposits that turbidity currents leave behind in the sedimentological record. However, deposits of individual flows are likely to be reworked by successive flows, but it is unclear as to what extent. How complete is the stratigraphy of these deposits? What percentage of flow deposits are preserved in the rock record? Are some events better preserved than others, and if so, why? We address these questions by re-analysing the most detailed time-lapse mapping yet of a turbidity current system. This field dataset comes from the fjord-head Squamish Delta in British Columbia, Canada where Hughes Clarke (2016) collected 93 near-daily repeat surveys in 2011. These surveys revealed the seafloor response to more than 100 turbidity currents. Here we use temporal changes in seabed elevation to understand patterns of deposition and erosion. We calculate the total thickness of sediment deposited at each location, and document the percentage of sediment that is preserved (i.e. stratigraphic completeness) at multiple time-steps over the surveyed period. The average stratigraphic completeness across the delta near submarine channels is <1%, but this is highly spatially variable. Some levees record up to 40% completeness. The low value is largely due to upstream migrating bedforms that constantly rework previously emplaced sediments. Surprisingly, even at the terminal lobes, stratigraphic completeness is typically <5%. These results provide new insights into the evolution of submarine channels and why their deposits produce a highly incomplete record of submarine flows.

  18. Stratigraphic Paleobiology of the Taranto Area

    NASA Astrophysics Data System (ADS)

    Scarponi, Daniele; Angeletti, Lorenzo; Taviani, Marco; Huntley, John Warren; Amorosi, Alessandro; Negri, Alessandra; Battista Vai, Gian

    2015-04-01

    The area surrounding Taranto, Italy is chronostratigraphically very important, as it is one of the few areas in the world where Upper Pleistocene marine successions are well exposed, easily accessible, and relatively thick. Several outcrops in this area were investigated as suitable marine sections for defining the Late Pleistocene GSSP. At these locations, the late Pleistocene bathymetric history of the Taranto area was depicted using macrobenthic assemblages from a network of outcrops and cores. Outcrops at Pontile, Fronte, and Garitta, along with two cores drilled at Cimino and Cantoro were densely sampled to conduct quantitatively-derived paleobathymetric reconstructions. These deposits yielded relatively diverse mollusk associations (> 250 species and > 9.000 specimens distributed among 55 samples), dominated by extant mollusk species of known bathymetric distribution. Multiple analytical approaches were applied to the macrobenthic dataset in a comparative fashion: (i) direct calibration by weighted averaging of taxa with known preferred depth recovered in a sample, (ii) posteriori-calibrated ordination (DCA) using bathymetric data of key extant taxa. These analyses were conducted at both species and genus level. Regardless of the choice of the analytical method, mollusk assemblages yielded bathymetric trends congruent with previous qualitative and semi-quantitative paleoecological and stratigraphic analyses: the bathymetric range of sampled deposits is bracketed between 140 and 0 meters. Secondly, macrobenthos-derived proxies provided an improved characterization of the marine deposits in terms of sample bathymetry and by discriminating shallowing-upward (regressive) trends from deepening-upward (transgressive) tendencies. Thirdly, mollusk-derived bathymetric inferences suggest spatial bathymetric gradients that are coherent with the morphology of the study area. In conclusion, the results provided an improved characterization of coastal depositional facies

  19. High resolution spectroscopic mapping imaging applied in situ to multilayer structures for stratigraphic identification of painted art objects

    NASA Astrophysics Data System (ADS)

    Karagiannis, Georgios Th.

    2016-04-01

    The development of non-destructive techniques is a reality in the field of conservation science. These techniques are usually not so accurate, as the analytical micro-sampling techniques, however, the proper development of soft-computing techniques can improve their accuracy. In this work, we propose a real-time fast acquisition spectroscopic mapping imaging system that operates from the ultraviolet to mid infrared (UV/Vis/nIR/mIR) area of the electromagnetic spectrum and it is supported by a set of soft-computing methods to identify the materials that exist in a stratigraphic structure of paint layers. Particularly, the system acquires spectra in diffuse-reflectance mode, scanning in a Region-Of-Interest (ROI), and having wavelength range from 200 up to 5000 nm. Also, a fuzzy c-means clustering algorithm, i.e., the particular soft-computing algorithm, produces the mapping images. The evaluation of the method was tested on a byzantine painted icon.

  20. Verification Test of Automated Robotic Assembly of Space Truss Structures

    NASA Technical Reports Server (NTRS)

    Rhodes, Marvin D.; Will, Ralph W.; Quach, Cuong C.

    1995-01-01

    A multidisciplinary program has been conducted at the Langley Research Center to develop operational procedures for supervised autonomous assembly of truss structures suitable for large-aperture antennas. The hardware and operations required to assemble a 102-member tetrahedral truss and attach 12 hexagonal panels were developed and evaluated. A brute-force automation approach was used to develop baseline assembly hardware and software techniques. However, as the system matured and operations were proven, upgrades were incorporated and assessed against the baseline test results. These upgrades included the use of distributed microprocessors to control dedicated end-effector operations, machine vision guidance for strut installation, and the use of an expert system-based executive-control program. This paper summarizes the developmental phases of the program, the results of several assembly tests, and a series of proposed enhancements. No problems that would preclude automated in-space assembly or truss structures have been encountered. The test system was developed at a breadboard level and continued development at an enhanced level is warranted.

  1. Government Draw Bentonite Beds: a newly identified stratigraphic marker in the Virgin Creek Member of the Pierre Shale, central South Dakota ( USA).

    USGS Publications Warehouse

    Nichols, T.C.; Chleborad, A.F.; Collins, D.S.

    1987-01-01

    A grouping of four bentonite beds, herein named the Government Draw Bentonite Beds, is identified as a stratigraphic marker within the Virgin Creek Member of the Pierre Shale. The beds are found west of Pierre, South Dakota, over an area of at least 130 mi2 (210 km2) where no other markers within the Virgin Creek Member have been identified. In this area, the Government Draw is a potential tool needed to determine the stratigraphic and structural relationships within the upper part of the Pierre Shale, heretofore little known. A better understanding of structural elements found in the Pierre Shale is needed to unravel the Late Cretaceous and younger geologic history of the area. -Authors

  2. A mixed optimization method for automated design of fuselage structures.

    NASA Technical Reports Server (NTRS)

    Sobieszczanski, J.; Loendorf, D.

    1972-01-01

    A procedure for automating the design of transport aircraft fuselage structures has been developed and implemented in the form of an operational program. The structure is designed in two stages. First, an overall distribution of structural material is obtained by means of optimality criteria to meet strength and displacement constraints. Subsequently, the detailed design of selected rings and panels consisting of skin and stringers is performed by mathematical optimization accounting for a set of realistic design constraints. The practicality and computer efficiency of the procedure is demonstrated on cylindrical and area-ruled large transport fuselages.

  3. Carbohydrate structure: the rocky road to automation.

    PubMed

    Agirre, Jon; Davies, Gideon J; Wilson, Keith S; Cowtan, Kevin D

    2017-06-01

    With the introduction of intuitive graphical software, structural biologists who are not experts in crystallography are now able to build complete protein or nucleic acid models rapidly. In contrast, carbohydrates are in a wholly different situation: scant automation exists, with manual building attempts being sometimes toppled by incorrect dictionaries or refinement problems. Sugars are the most stereochemically complex family of biomolecules and, as pyranose rings, have clear conformational preferences. Despite this, all refinement programs may produce high-energy conformations at medium to low resolution, without any support from the electron density. This problem renders the affected structures unusable in glyco-chemical terms. Bringing structural glycobiology up to 'protein standards' will require a total overhaul of the methodology. Time is of the essence, as the community is steadily increasing the production rate of glycoproteins, and electron cryo-microscopy has just started to image them in precisely that resolution range where crystallographic methods falter most. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Development and verification testing of automation and robotics for assembly of space structures

    NASA Technical Reports Server (NTRS)

    Rhodes, Marvin D.; Will, Ralph W.; Quach, Cuong C.

    1993-01-01

    A program was initiated within the past several years to develop operational procedures for automated assembly of truss structures suitable for large-aperture antennas. The assembly operations require the use of a robotic manipulator and are based on the principle of supervised autonomy to minimize crew resources. A hardware testbed was established to support development and evaluation testing. A brute-force automation approach was used to develop the baseline assembly hardware and software techniques. As the system matured and an operation was proven, upgrades were incorprated and assessed against the baseline test results. This paper summarizes the developmental phases of the program, the results of several assembly tests, the current status, and a series of proposed developments for additional hardware and software control capability. No problems that would preclude automated in-space assembly of truss structures have been encountered. The current system was developed at a breadboard level and continued development at an enhanced level is warranted.

  5. Automated crack detection in conductive smart-concrete structures using a resistor mesh model

    NASA Astrophysics Data System (ADS)

    Downey, Austin; D'Alessandro, Antonella; Ubertini, Filippo; Laflamme, Simon

    2018-03-01

    Various nondestructive evaluation techniques are currently used to automatically detect and monitor cracks in concrete infrastructure. However, these methods often lack the scalability and cost-effectiveness over large geometries. A solution is the use of self-sensing carbon-doped cementitious materials. These self-sensing materials are capable of providing a measurable change in electrical output that can be related to their damage state. Previous work by the authors showed that a resistor mesh model could be used to track damage in structural components fabricated from electrically conductive concrete, where damage was located through the identification of high resistance value resistors in a resistor mesh model. In this work, an automated damage detection strategy that works through placing high value resistors into the previously developed resistor mesh model using a sequential Monte Carlo method is introduced. Here, high value resistors are used to mimic the internal condition of damaged cementitious specimens. The proposed automated damage detection method is experimentally validated using a 500 × 500 × 50 mm3 reinforced cement paste plate doped with multi-walled carbon nanotubes exposed to 100 identical impact tests. Results demonstrate that the proposed Monte Carlo method is capable of detecting and localizing the most prominent damage in a structure, demonstrating that automated damage detection in smart-concrete structures is a promising strategy for real-time structural health monitoring of civil infrastructure.

  6. Automated 3D structure composition for large RNAs

    PubMed Central

    Popenda, Mariusz; Szachniuk, Marta; Antczak, Maciej; Purzycka, Katarzyna J.; Lukasiak, Piotr; Bartol, Natalia; Blazewicz, Jacek; Adamiak, Ryszard W.

    2012-01-01

    Understanding the numerous functions that RNAs play in living cells depends critically on knowledge of their three-dimensional structure. Due to the difficulties in experimentally assessing structures of large RNAs, there is currently great demand for new high-resolution structure prediction methods. We present the novel method for the fully automated prediction of RNA 3D structures from a user-defined secondary structure. The concept is founded on the machine translation system. The translation engine operates on the RNA FRABASE database tailored to the dictionary relating the RNA secondary structure and tertiary structure elements. The translation algorithm is very fast. Initial 3D structure is composed in a range of seconds on a single processor. The method assures the prediction of large RNA 3D structures of high quality. Our approach needs neither structural templates nor RNA sequence alignment, required for comparative methods. This enables the building of unresolved yet native and artificial RNA structures. The method is implemented in a publicly available, user-friendly server RNAComposer. It works in an interactive mode and a batch mode. The batch mode is designed for large-scale modelling and accepts atomic distance restraints. Presently, the server is set to build RNA structures of up to 500 residues. PMID:22539264

  7. Additive Construction with Mobile Emplacement (ACME) / Automated Construction of Expeditionary Structures (ACES) Materials Delivery System (MDS)

    NASA Technical Reports Server (NTRS)

    Mueller, R. P.; Townsend, I. I.; Tamasy, G. J.; Evers, C. J.; Sibille, L. J.; Edmunson, J. E.; Fiske, M. R.; Fikes, J. C.; Case, M.

    2018-01-01

    The purpose of the Automated Construction of Expeditionary Structures, Phase 3 (ACES 3) project is to incorporate the Liquid Goods Delivery System (LGDS) into the Dry Goods Delivery System (DGDS) structure to create an integrated and automated Materials Delivery System (MDS) for 3D printing structures with ordinary Portland cement (OPC) concrete. ACES 3 is a prototype for 3-D printing barracks for soldiers in forward bases, here on Earth. The LGDS supports ACES 3 by storing liquid materials, mixing recipe batches of liquid materials, and working with the Dry Goods Feed System (DGFS) previously developed for ACES 2, combining the materials that are eventually extruded out of the print nozzle. Automated Construction of Expeditionary Structures, Phase 3 (ACES 3) is a project led by the US Army Corps of Engineers (USACE) and supported by NASA. The equivalent 3D printing system for construction in space is designated Additive Construction with Mobile Emplacement (ACME) by NASA.

  8. SAS program for quantitative stratigraphic correlation by principal components

    USGS Publications Warehouse

    Hohn, M.E.

    1985-01-01

    A SAS program is presented which constructs a composite section of stratigraphic events through principal components analysis. The variables in the analysis are stratigraphic sections and the observational units are range limits of taxa. The program standardizes data in each section, extracts eigenvectors, estimates missing range limits, and computes the composite section from scores of events on the first principal component. Provided is an option of several types of diagnostic plots; these help one to determine conservative range limits or unrealistic estimates of missing values. Inspection of the graphs and eigenvalues allow one to evaluate goodness of fit between the composite and measured data. The program is extended easily to the creation of a rank-order composite. ?? 1985.

  9. Automating a Detailed Cognitive Task Analysis for Structuring Curriculum

    DTIC Science & Technology

    1991-08-01

    1991-- ] Aleeo/i ISM’-19# l Title: Automating a Detailed Cognitive Task Analysis for Structuring Curriculum Activities: To date we have completed task...The Institute for Management Sciences. Although the particular application of the modified GOMS cognitive task analysis technique under development is...Laboratories 91 9 23 074 Automnating a Detailed Cognitive Task Analysis For Stucuring Curriculum Research Plan Year 1 Task 1.0 Design Task 1.1 Conduct body

  10. The modified gap excess ratio (GER*) and the stratigraphic congruence of dinosaur phylogenies.

    PubMed

    Wills, Matthew A; Barrett, Paul M; Heathcote, Julia F

    2008-12-01

    Palaeontologists routinely map their cladograms onto what is known of the fossil record. Where sister taxa first appear as fossils at different times, a ghost range is inferred to bridge the gap between these dates. Some measure of the total extent of ghost ranges across the tree underlies several indices of cladistic/stratigraphic congruence. We investigate this congruence for 19 independent, published cladograms of major dinosaur groups and report exceptional agreement between the phylogenetic and stratigraphic patterns, evidenced by sums of ghost ranges near the theoretical minima. This implies that both phylogenetic and stratigraphic data reflect faithfully the evolutionary history of dinosaurs, at least for the taxa included in this study. We formally propose modifications to an existing index of congruence (the gap excess ratio; GER), designed to remove a bias in the range of values possible with trees of different shapes. We also propose a more informative index of congruence--GER*--that takes account of the underlying distribution of sums of ghost ranges possible when permuting stratigraphic range data across the tree. Finally, we incorporate data on the range of possible first occurrence dates into our estimates of congruence, extending a procedure originally implemented with the modified Manhattan stratigraphic measure and GER to our new indices. Most dinosaur data sets maintain extremely high congruence despite such modifications.

  11. Storage Thresholds for Relative Sea Level Signals in the Stratigraphic Record

    NASA Astrophysics Data System (ADS)

    Li, Q.; Yu, L.; Straub, K. M.

    2015-12-01

    Many argue that the tug of Relative Sea Level (RSL) change represents the most important allogenic forcing affecting deltas and is the primary control on stratigraphic architecture of deltas. However, the range of amplitudes and periodicities of RSL cycles stored in stratigraphy remains unknown. Here we use a suite of physical experiments to show that RSL cycles with magnitudes and periodicities less than the spatial and temporal scales of deltaic internal (autogenic) dynamics cannot confidently be extracted from the physical stratigraphic record. Additional analysis of deltaic morphodynamics also suggest no significant differences between an experiment with constant boundary conditions (control experiment) and an experiment with small magnitude and short periodicity RSL cycles, relative to the autogenic dynamics. Significant differences in the aspect ratio of channel bodies and deposit sand fractions do exists between our control experiment and those experiments with either large magnitudes or long periodicities RSL cycles. Using a compilation of data from major river delta systems, we show that our predicted thresholds for RSL signal storage often overlap with the magnitudes and periodicities of commonly discussed drivers of global sea level. This theory defines quantitative limits on the range of paleo-RSL information that can be extracted from the stratigraphic record, which could aid stratigraphic prediction and the inversion of stratigraphy for paleo- deltaic response to climate change.

  12. Knowledge structure representation and automated updates in intelligent information management systems

    NASA Technical Reports Server (NTRS)

    Corey, Stephen; Carnahan, Richard S., Jr.

    1990-01-01

    A continuing effort to apply rapid prototyping and Artificial Intelligence techniques to problems associated with projected Space Station-era information management systems is examined. In particular, timely updating of the various databases and knowledge structures within the proposed intelligent information management system (IIMS) is critical to support decision making processes. Because of the significantly large amounts of data entering the IIMS on a daily basis, information updates will need to be automatically performed with some systems requiring that data be incorporated and made available to users within a few hours. Meeting these demands depends first, on the design and implementation of information structures that are easily modified and expanded, and second, on the incorporation of intelligent automated update techniques that will allow meaningful information relationships to be established. Potential techniques are studied for developing such an automated update capability and IIMS update requirements are examined in light of results obtained from the IIMS prototyping effort.

  13. StrAuto: automation and parallelization of STRUCTURE analysis.

    PubMed

    Chhatre, Vikram E; Emerson, Kevin J

    2017-03-24

    Population structure inference using the software STRUCTURE has become an integral part of population genetic studies covering a broad spectrum of taxa including humans. The ever-expanding size of genetic data sets poses computational challenges for this analysis. Although at least one tool currently implements parallel computing to reduce computational overload of this analysis, it does not fully automate the use of replicate STRUCTURE analysis runs required for downstream inference of optimal K. There is pressing need for a tool that can deploy population structure analysis on high performance computing clusters. We present an updated version of the popular Python program StrAuto, to streamline population structure analysis using parallel computing. StrAuto implements a pipeline that combines STRUCTURE analysis with the Evanno Δ K analysis and visualization of results using STRUCTURE HARVESTER. Using benchmarking tests, we demonstrate that StrAuto significantly reduces the computational time needed to perform iterative STRUCTURE analysis by distributing runs over two or more processors. StrAuto is the first tool to integrate STRUCTURE analysis with post-processing using a pipeline approach in addition to implementing parallel computation - a set up ideal for deployment on computing clusters. StrAuto is distributed under the GNU GPL (General Public License) and available to download from http://strauto.popgen.org .

  14. Automated extraction of chemical structure information from digital raster images

    PubMed Central

    Park, Jungkap; Rosania, Gus R; Shedden, Kerby A; Nguyen, Mandee; Lyu, Naesung; Saitou, Kazuhiro

    2009-01-01

    Background To search for chemical structures in research articles, diagrams or text representing molecules need to be translated to a standard chemical file format compatible with cheminformatic search engines. Nevertheless, chemical information contained in research articles is often referenced as analog diagrams of chemical structures embedded in digital raster images. To automate analog-to-digital conversion of chemical structure diagrams in scientific research articles, several software systems have been developed. But their algorithmic performance and utility in cheminformatic research have not been investigated. Results This paper aims to provide critical reviews for these systems and also report our recent development of ChemReader – a fully automated tool for extracting chemical structure diagrams in research articles and converting them into standard, searchable chemical file formats. Basic algorithms for recognizing lines and letters representing bonds and atoms in chemical structure diagrams can be independently run in sequence from a graphical user interface-and the algorithm parameters can be readily changed-to facilitate additional development specifically tailored to a chemical database annotation scheme. Compared with existing software programs such as OSRA, Kekule, and CLiDE, our results indicate that ChemReader outperforms other software systems on several sets of sample images from diverse sources in terms of the rate of correct outputs and the accuracy on extracting molecular substructure patterns. Conclusion The availability of ChemReader as a cheminformatic tool for extracting chemical structure information from digital raster images allows research and development groups to enrich their chemical structure databases by annotating the entries with published research articles. Based on its stable performance and high accuracy, ChemReader may be sufficiently accurate for annotating the chemical database with links to scientific research

  15. Discovery of Jurassic ammonite-bearing series in Jebel Bou Hedma (South-Central Tunisian Atlas): Implications for stratigraphic correlations and paleogeographic reconstruction

    NASA Astrophysics Data System (ADS)

    Bahrouni, Néjib; Houla, Yassine; Soussi, Mohamed; Boughdiri, Mabrouk; Ali, Walid Ben; Nasri, Ahmed; Bouaziz, Samir

    2016-01-01

    Recent geological mapping undertaken in the Southern-Central Atlas of Tunisia led to the discovery of Jurassic ammonite-bearing series in the Jebel Bou Hedma E-W anticline structure. These series represent the Southernmost Jurassic rocks ever documented in the outcrops of the Tunisian Atlas. These series which outcrop in a transitional zone between the Southern Tunisian Atlas and the Chott basin offer a valuable benchmark for new stratigraphic correlation with the well-known Jurassic series of the North-South Axis of Central Tunisia and also with the Jurassic subsurface successions transected by petroleum wells in the study area. The preliminary investigations allowed the identification, within the most complete section outcropping in the center of the structure, of numerous useful biochronological and sedimentological markers helping in the establishment of an updated Jurassic stratigraphic framework chart of South-Western Tunisia. Additionally, the Late Jurassic succession documents syn-sedimentary features such as slumping, erosion and reworking of sediments and ammonite faunas that can be considered as strong witnesses of an important geodynamic event around the Jurassic-Cretaceous boundary. These stratigraphic and geodynamic new data make of the Jurassic of Jebel Bou Hedma a key succession for stratigraphic correlation attempt between Atlas Tunisian series and those currently buried in the Chott basin or outcropping in the Saharan platform. Furthermore, the several rich-ammonite identified horizons within the Middle and Upper Jurassic series constitute reliable time lines that can be useful for both paleogeographic and geodynamic reconstructions of this part of the North African Tethyan margin but also in the refinement of the potential migration routes for ammonite populations from the Maghrebian Southern Tethys to Arabia.

  16. Automated Reconstruction of Historic Roof Structures from Point Clouds - Development and Examples

    NASA Astrophysics Data System (ADS)

    Pöchtrager, M.; Styhler-Aydın, G.; Döring-Williams, M.; Pfeifer, N.

    2017-08-01

    The analysis of historic roof constructions is an important task for planning the adaptive reuse of buildings or for maintenance and restoration issues. Current approaches to modeling roof constructions consist of several consecutive operations that need to be done manually or using semi-automatic routines. To increase efficiency and allow the focus to be on analysis rather than on data processing, a set of methods was developed for the fully automated analysis of the roof constructions, including integration of architectural and structural modeling. Terrestrial laser scanning permits high-detail surveying of large-scale structures within a short time. Whereas 3-D laser scan data consist of millions of single points on the object surface, we need a geometric description of structural elements in order to obtain a structural model consisting of beam axis and connections. Preliminary results showed that the developed methods work well for beams in flawless condition with a quadratic cross section and no bending. Deformations or damages such as cracks and cuts on the wooden beams can lead to incomplete representations in the model. Overall, a high degree of automation was achieved.

  17. Multidisciplinary approach for fault detection: Integration of PS-InSAR, geomorphological, stratigraphic and structural data in the Venafro intermontane basin (Central-Southern Apennines, Italy)

    NASA Astrophysics Data System (ADS)

    Amato, Vincenzo; Aucelli, Pietro P. C.; Bellucci Sessa, Eliana; Cesarano, Massimo; Incontri, Pietro; Pappone, Gerardo; Valente, Ettore; Vilardo, Giuseppe

    2017-04-01

    A multidisciplinary methodology, integrating stratigraphic, geomorphological and structural data, combined with GIS-aided analysis and PS-InSAR interferometric data, was applied to characterize the relationships between ground deformations and the stratigraphic and the morphostructural setting of the Venafro intermontane basin. This basin is a morphostructural depression related to NW-SE and NE-SW oriented high angle normal faults bordering and crossing it. In particular, a well-known active fault crossing the plain is the Aquae Juliae Fault, whose recent activity is evidenced by archeoseismological data. The approach applied here reveals new evidence of possible faulting, acting during the Lower to Upper Pleistocene, which has driven the morphotectonic and the environmental evolution of the basin. In particular, the tectonic setting emerging from this study highlights the influence of the NW-SE oriented extensional phase during the late Lower Pleistocene - early Middle Pleistocene, in the generation of NE-SW trending, SE dipping, high-angle faults and NW-SE trending, high-angle transtensive faults. This phase has been followed by a NE-SW extensional one, responsible for the formation of NW-SE trending, both NW and SE dipping, high-angle normal faults, and the reactivation of the oldest NE-SW oriented structures. These NW-SE trending normal faults include the Aquae Juliae Fault and a new one, unknown until now, crossing the plain between the Venafro village and the Colle Cupone Mt. (hereinafter named the Venafro-Colle Cupone Fault, VCCF). This fault has controlled deposition of the youngest sedimentary units (late Middle Pleistocene to late Upper Pleistocene) suggesting its recent activity and it is well constrained by PS-InSAR data, as testified by the increase of the subsidence rate in the hanging wall block.

  18. Integrating automated structured analysis and design with Ada programming support environments

    NASA Technical Reports Server (NTRS)

    Hecht, Alan; Simmons, Andy

    1986-01-01

    Ada Programming Support Environments (APSE) include many powerful tools that address the implementation of Ada code. These tools do not address the entire software development process. Structured analysis is a methodology that addresses the creation of complete and accurate system specifications. Structured design takes a specification and derives a plan to decompose the system subcomponents, and provides heuristics to optimize the software design to minimize errors and maintenance. It can also produce the creation of useable modules. Studies have shown that most software errors result from poor system specifications, and that these errors also become more expensive to fix as the development process continues. Structured analysis and design help to uncover error in the early stages of development. The APSE tools help to insure that the code produced is correct, and aid in finding obscure coding errors. However, they do not have the capability to detect errors in specifications or to detect poor designs. An automated system for structured analysis and design TEAMWORK, which can be integrated with an APSE to support software systems development from specification through implementation is described. These tools completement each other to help developers improve quality and productivity, as well as to reduce development and maintenance costs. Complete system documentation and reusable code also resultss from the use of these tools. Integrating an APSE with automated tools for structured analysis and design provide capabilities and advantages beyond those realized with any of these systems used by themselves.

  19. Paleorift structure constrained by gravity and stratigraphic data: The Statherian Araí rift case

    NASA Astrophysics Data System (ADS)

    Martins-Ferreira, Marco Antonio Caçador; Campos, José Eloi Guimarães; Von Huelsen, Monica Giannoccaro; Neri, Brandow Lee

    2018-07-01

    Gravimetric and stratigraphic data were used to investigate the Paleoproterozoic Araí Paleorift, a failed Statherian continental rift located in the western margin of the São Francisco Craton, where basement and cover were affected by the Neoproterozoic Brasiliano Orogeny. Euler deconvolution, tilt, total horizontal gradient amplitude and upward continuation technics were applied to terrestrial gravimetric data in order to investigate the rift's main faults location, direction and depth, allowing to identify its main horsts, grabens, volcanic and plutonic centers. We found that rift faults occur to a maximum depth of ca. 38 km, but major fault throw occurs from 4 to 8 km deep and attenuates from 8 to 12 km, probably the brittle-ductile transition zone at the time of rifting, practically disappearing at 20 km. Stratigraphic data and basement mapping were used in order to constraint gravimetric results. We classify the Araí Rift as a passive, three-armed failed rift, narrow to divergent type, that produced preferably anorogenic rapakivi-related magmas, most of it still lodged in the crust from surface down to ca. 19 km deep and subsidiary mafic magmatism. The results indicate the deep occurrence of low-density magmas beneath the rift's main axis, detected up to 20 km deep. Correlation to other global Statherian rifts show that the São Francisco Craton was strongly affected by taphrogenesis during the Statherian, together with Siberia, North America and North China cratons. Finally, by comparing our results to recent rifts we found that the Ethiopian rift's morphology is quite similar to the Araí. Surrounding the Tanzanian craton, the Cenozoic East Africa rift system morphology is compared to the Araí-Espinhaço rift system, which surrounds the São Francisco craton. The major contribution of this paper is the recognition of Araí Paleorift surface and subsurface morphology, up to now unknown, over an area of ca. 45.000 km2.

  20. 3D Stratigraphic Modeling of Central Aachen

    NASA Astrophysics Data System (ADS)

    Dong, M.; Neukum, C.; Azzam, R.; Hu, H.

    2010-05-01

    Since 1980s, advanced computer hardware and software technologies, as well as multidisciplinary research have provided possibilities to develop advanced three dimensional (3D) simulation software for geosciences application. Some countries, such as USA1) and Canada2) 3), have built up regional 3D geological models based on archival geological data. Such models have played huge roles in engineering geology2), hydrogeology2) 3), geothermal industry1) and so on. In cooperating with the Municipality of Aachen, the Department of Engineering Geology of RWTH Aachen University have built up a computer-based 3D stratigraphic model of 50 meter' depth for the center of Aachen, which is a 5 km by 7 km geologically complex area. The uncorrelated data from multi-resources, discontinuous nature and unconformable connection of the units are main challenges for geological modeling in this area. The reliability of 3D geological models largely depends on the quality and quantity of data. Existing 1D and 2D geological data were collected, including 1) approximately 6970 borehole data of different depth compiled in Microsoft Access database and MapInfo database; 2) a Digital Elevation Model (DEM); 3) geological cross sections; and 4) stratigraphic maps in 1m, 2m and 5m depth. Since acquired data are of variable origins, they were managed step by step. The main processes are described below: 1) Typing errors of borehole data were identified and the corrected data were exported to Variowin2.2 to distinguish duplicate points; 2) The surface elevation of borehole data was compared to the DEM, and differences larger than 3m were eliminated. Moreover, where elevation data missed, it was read from the DEM; 3) Considerable data were collected from municipal constructions, such as residential buildings, factories, and roads. Therefore, many boreholes are spatially clustered, and only one or two representative points were picked out in such areas; After above procedures, 5839 boreholes with -x

  1. Preliminary Stratigraphic Basis for Geologic Mapping of Venus

    NASA Technical Reports Server (NTRS)

    Basilevsky, A. T.; Head, J. W.

    1993-01-01

    The age relations between geologic formations have been studied at 36 1000x1000 km areas centered at the dark paraboloid craters. The geologic setting in all these sites could be characterized using only 16 types of features and terrains (units). These units form a basic stratigraphic sequence (from older to younger: (1) Tessera (Tt); (2-3) Densely fractured terrains associated with coronae (COdf) and in the form of remnants among plains (Pdf); (4) Fractured and ridged plains (Pfr); (5) Plains with wrinkle ridges (Pwr); (6-7) Smooth and lobate plains (Ps/Pl); and (8) Rift-associated fractures (Fra). The stratigraphic position of the other units is determined by their relation with the units of the basic sequence: (9) Ridge bells (RB), contemporary with Pfr; (10-11) Ridges of coronae and arachnoids annuli (COar/Aar), contemporary with wrinkle ridges of Pwr; (12) Fractures of coronae annuli (COaf) disrupt Pwr and Ps/Pl; (13) Fractures (F) disrupt Pwr or younger units; (14) Craters with associated dark paraboloids (Cdp), which are on top of all volcanic and tectonic units except the youngest episodes of rift-associated fracturing and volcanism; (15-16) Surficial streaks (Ss) and surficial patches (Sp) are approximately contemporary with Cdp. These units may be used as a tentative basis for the geologic mapping of Venus including VMAP. This mapping should test the stratigraphy and answer the question of whether this stratigraphic sequence corresponds to geologic events which were generally synchronous all around the planet or whether the sequence is simply a typical sequence of events which occurred in different places at diffferent times.

  2. Automated quantification of renal interstitial fibrosis for computer-aided diagnosis: A comprehensive tissue structure segmentation method.

    PubMed

    Tey, Wei Keat; Kuang, Ye Chow; Ooi, Melanie Po-Leen; Khoo, Joon Joon

    2018-03-01

    Interstitial fibrosis in renal biopsy samples is a scarring tissue structure that may be visually quantified by pathologists as an indicator to the presence and extent of chronic kidney disease. The standard method of quantification by visual evaluation presents reproducibility issues in the diagnoses. This study proposes an automated quantification system for measuring the amount of interstitial fibrosis in renal biopsy images as a consistent basis of comparison among pathologists. The system extracts and segments the renal tissue structures based on colour information and structural assumptions of the tissue structures. The regions in the biopsy representing the interstitial fibrosis are deduced through the elimination of non-interstitial fibrosis structures from the biopsy area and quantified as a percentage of the total area of the biopsy sample. A ground truth image dataset has been manually prepared by consulting an experienced pathologist for the validation of the segmentation algorithms. The results from experiments involving experienced pathologists have demonstrated a good correlation in quantification result between the automated system and the pathologists' visual evaluation. Experiments investigating the variability in pathologists also proved the automated quantification error rate to be on par with the average intra-observer variability in pathologists' quantification. Interstitial fibrosis in renal biopsy samples is a scarring tissue structure that may be visually quantified by pathologists as an indicator to the presence and extent of chronic kidney disease. The standard method of quantification by visual evaluation presents reproducibility issues in the diagnoses due to the uncertainties in human judgement. An automated quantification system for accurately measuring the amount of interstitial fibrosis in renal biopsy images is presented as a consistent basis of comparison among pathologists. The system identifies the renal tissue structures

  3. Deep Learning and Image Processing for Automated Crack Detection and Defect Measurement in Underground Structures

    NASA Astrophysics Data System (ADS)

    Panella, F.; Boehm, J.; Loo, Y.; Kaushik, A.; Gonzalez, D.

    2018-05-01

    This work presents the combination of Deep-Learning (DL) and image processing to produce an automated cracks recognition and defect measurement tool for civil structures. The authors focus on tunnel civil structures and survey and have developed an end to end tool for asset management of underground structures. In order to maintain the serviceability of tunnels, regular inspection is needed to assess their structural status. The traditional method of carrying out the survey is the visual inspection: simple, but slow and relatively expensive and the quality of the output depends on the ability and experience of the engineer as well as on the total workload (stress and tiredness may influence the ability to observe and record information). As a result of these issues, in the last decade there is the desire to automate the monitoring using new methods of inspection. The present paper has the goal of combining DL with traditional image processing to create a tool able to detect, locate and measure the structural defect.

  4. Automated glioblastoma segmentation based on a multiparametric structured unsupervised classification.

    PubMed

    Juan-Albarracín, Javier; Fuster-Garcia, Elies; Manjón, José V; Robles, Montserrat; Aparici, F; Martí-Bonmatí, L; García-Gómez, Juan M

    2015-01-01

    Automatic brain tumour segmentation has become a key component for the future of brain tumour treatment. Currently, most of brain tumour segmentation approaches arise from the supervised learning standpoint, which requires a labelled training dataset from which to infer the models of the classes. The performance of these models is directly determined by the size and quality of the training corpus, whose retrieval becomes a tedious and time-consuming task. On the other hand, unsupervised approaches avoid these limitations but often do not reach comparable results than the supervised methods. In this sense, we propose an automated unsupervised method for brain tumour segmentation based on anatomical Magnetic Resonance (MR) images. Four unsupervised classification algorithms, grouped by their structured or non-structured condition, were evaluated within our pipeline. Considering the non-structured algorithms, we evaluated K-means, Fuzzy K-means and Gaussian Mixture Model (GMM), whereas as structured classification algorithms we evaluated Gaussian Hidden Markov Random Field (GHMRF). An automated postprocess based on a statistical approach supported by tissue probability maps is proposed to automatically identify the tumour classes after the segmentations. We evaluated our brain tumour segmentation method with the public BRAin Tumor Segmentation (BRATS) 2013 Test and Leaderboard datasets. Our approach based on the GMM model improves the results obtained by most of the supervised methods evaluated with the Leaderboard set and reaches the second position in the ranking. Our variant based on the GHMRF achieves the first position in the Test ranking of the unsupervised approaches and the seventh position in the general Test ranking, which confirms the method as a viable alternative for brain tumour segmentation.

  5. Automated Glioblastoma Segmentation Based on a Multiparametric Structured Unsupervised Classification

    PubMed Central

    Juan-Albarracín, Javier; Fuster-Garcia, Elies; Manjón, José V.; Robles, Montserrat; Aparici, F.; Martí-Bonmatí, L.; García-Gómez, Juan M.

    2015-01-01

    Automatic brain tumour segmentation has become a key component for the future of brain tumour treatment. Currently, most of brain tumour segmentation approaches arise from the supervised learning standpoint, which requires a labelled training dataset from which to infer the models of the classes. The performance of these models is directly determined by the size and quality of the training corpus, whose retrieval becomes a tedious and time-consuming task. On the other hand, unsupervised approaches avoid these limitations but often do not reach comparable results than the supervised methods. In this sense, we propose an automated unsupervised method for brain tumour segmentation based on anatomical Magnetic Resonance (MR) images. Four unsupervised classification algorithms, grouped by their structured or non-structured condition, were evaluated within our pipeline. Considering the non-structured algorithms, we evaluated K-means, Fuzzy K-means and Gaussian Mixture Model (GMM), whereas as structured classification algorithms we evaluated Gaussian Hidden Markov Random Field (GHMRF). An automated postprocess based on a statistical approach supported by tissue probability maps is proposed to automatically identify the tumour classes after the segmentations. We evaluated our brain tumour segmentation method with the public BRAin Tumor Segmentation (BRATS) 2013 Test and Leaderboard datasets. Our approach based on the GMM model improves the results obtained by most of the supervised methods evaluated with the Leaderboard set and reaches the second position in the ranking. Our variant based on the GHMRF achieves the first position in the Test ranking of the unsupervised approaches and the seventh position in the general Test ranking, which confirms the method as a viable alternative for brain tumour segmentation. PMID:25978453

  6. Automated real-time structure health monitoring via signature pattern recognition

    NASA Astrophysics Data System (ADS)

    Sun, Fanping P.; Chaudhry, Zaffir A.; Rogers, Craig A.; Majmundar, M.; Liang, Chen

    1995-05-01

    Described in this paper are the details of an automated real-time structure health monitoring system. The system is based on structural signature pattern recognition. It uses an array of piezoceramic patches bonded to the structure as integrated sensor-actuators, an electric impedance analyzer for structural frequency response function acquisition and a PC for control and graphic display. An assembled 3-bay truss structure is employed as a test bed. Two issues, the localization of sensing area and the sensor temperature drift, which are critical for the success of this technique are addressed and a novel approach of providing temperature compensation using probability correlation function is presented. Due to the negligible weight and size of the solid-state sensor array and its ability to sense incipient-type damage, the system can eventually be implemented on many types of structures such as aircraft, spacecraft, large-span dome roof and steel bridges requiring multilocation and real-time health monitoring.

  7. Remote Stratigraphic Analysis: Combined TM and AIS Results in the Wind River/bighorn Basin Area, Wyoming

    NASA Technical Reports Server (NTRS)

    Lang, H. R.; Paylor, E. D.; Adams, S.

    1985-01-01

    An in-progress study demonstrates the utility of airborne imaging spectrometer (AIS) data for unraveling the stratigraphic evolution of a North American, western interior foreland basin. AIS data are used to determine the stratigraphic distribution of mineralogical facies that are diagnostic of specific depositional environments. After wavelength and amplitude calibration using natural ground targets with known spectral characteristics, AIS data identify calcite, dolomite, gypsum and montmorillonite-bearing strata in the Permian-Cretaceous sequence. Combined AIS and TM results illustrate the feasibility of spectral stratigraphy, remote analysis of stratigraphic sequences.

  8. A two-level structure for advanced space power system automation

    NASA Technical Reports Server (NTRS)

    Loparo, Kenneth A.; Chankong, Vira

    1990-01-01

    The tasks to be carried out during the three-year project period are: (1) performing extensive simulation using existing mathematical models to build a specific knowledge base of the operating characteristics of space power systems; (2) carrying out the necessary basic research on hierarchical control structures, real-time quantitative algorithms, and decision-theoretic procedures; (3) developing a two-level automation scheme for fault detection and diagnosis, maintenance and restoration scheduling, and load management; and (4) testing and demonstration. The outlines of the proposed system structure that served as a master plan for this project, work accomplished, concluding remarks, and ideas for future work are also addressed.

  9. Stratigraphic Profiles for Selected Hanford Site Seismometer Stations and Other Locations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Last, George V.

    2014-02-01

    Stratigraphic profiles were constructed for eight selected Hanford Site seismometer stations, five Hanford Site facility reference locations, and seven regional three-component broadband seismometer stations. These profiles provide interpretations of the subsurface layers to support estimation of ground motions from past earthquakes, and the prediction of ground motions from future earthquakes. In most cases these profiles terminated at the top of the Wanapum Basalt, but at selected sites profiles were extended down to the top of the crystalline basement. The composite one-dimensional stratigraphic profiles were based primarily on previous interpretations from nearby boreholes, and in many cases the nearest deep boreholemore » is located kilometers away.« less

  10. Seismic attenuation of the inner core: Viscoelastic or stratigraphic?

    USGS Publications Warehouse

    Cormier, V.F.; Xu, L.; Choy, G.L.

    1998-01-01

    Broadband velocity waveforms of PKIKP in the distance range 150??to 180??are inverted for inner core attenuation. A mean Q?? of 244 is determined at 1 Hz from 8 polar and 9 equatorial paths. The scatter in measured Q-1 exceeds individual error estimates, suggesting significant variation in attenuation with path. These results are interpreted by (1) viscoelasticity, in which the relaxation spectrum has a low-frequency corner near or slightly above the frequency band of short-period body waves, and by (2) stratigraphic (scattering) attenuation, in which attenuation and pulse broadening are caused by the interference of scattered multiples in a velocity structure having rapid fluctuations along a PKIKP path. In the scattering interpretation, PKIKP attenuation is only weakly affected by the intrinsic shear attenuation measured in the free-oscillation band. Instead, its frequency dependence, path variations, and fluctuations are all explained by scattering attenuation in a heterogeneous fabric resulting from solidification texturing of intrinsically anisotropic iron. The requisite fabric may consist of either single or ordered groups of crystals with P velocity differences of at least 5% and as much as 12% between two crystallographic axes at scale lengths of 0.5 to 2 km in the direction parallel to the axis of rotation and longer in the cylindrically radial direction, perpendicular to the axis of rotation.Broadband velocity waveforms of PKIKP in the distance range 150?? to 180?? are inverted for inner core attenuation. A mean Q?? of 244 is determined at 1 Hz from 8 polar and 9 equatorial paths. The scatter in the measured Q-1 exceeds individual error estimates, indicating significant variation in attenuation with path. The results are interpreted by viscoelasticity and stratigraphic (scattering) attenuation.

  11. Fossil preservation and the stratigraphic ranges of taxa

    NASA Technical Reports Server (NTRS)

    Foote, M.; Raup, D. M.

    1996-01-01

    The incompleteness of the fossil record hinders the inference of evolutionary rates and patterns. Here, we derive relationships among true taxonomic durations, preservation probability, and observed taxonomic ranges. We use these relationships to estimate original distributions of taxonomic durations, preservation probability, and completeness (proportion of taxa preserved), given only the observed ranges. No data on occurrences within the ranges of taxa are required. When preservation is random and the original distribution of durations is exponential, the inference of durations, preservability, and completeness is exact. However, reasonable approximations are possible given non-exponential duration distributions and temporal and taxonomic variation in preservability. Thus, the approaches we describe have great potential in studies of taphonomy, evolutionary rates and patterns, and genealogy. Analyses of Upper Cambrian-Lower Ordovician trilobite species, Paleozoic crinoid genera, Jurassic bivalve species, and Cenozoic mammal species yield the following results: (1) The preservation probability inferred from stratigraphic ranges alone agrees with that inferred from the analysis of stratigraphic gaps when data on the latter are available. (2) Whereas median durations based on simple tabulations of observed ranges are biased by stratigraphic resolution, our estimates of median duration, extinction rate, and completeness are not biased.(3) The shorter geologic ranges of mammalian species relative to those of bivalves cannot be attributed to a difference in preservation potential. However, we cannot rule out the contribution of taxonomic practice to this difference. (4) In the groups studied, completeness (proportion of species [trilobites, bivalves, mammals] or genera [crinoids] preserved) ranges from 60% to 90%. The higher estimates of completeness at smaller geographic scales support previous suggestions that the incompleteness of the fossil record reflects loss of

  12. PONDEROSA, an automated 3D-NOESY peak picking program, enables automated protein structure determination.

    PubMed

    Lee, Woonghee; Kim, Jin Hae; Westler, William M; Markley, John L

    2011-06-15

    PONDEROSA (Peak-picking Of Noe Data Enabled by Restriction of Shift Assignments) accepts input information consisting of a protein sequence, backbone and sidechain NMR resonance assignments, and 3D-NOESY ((13)C-edited and/or (15)N-edited) spectra, and returns assignments of NOESY crosspeaks, distance and angle constraints, and a reliable NMR structure represented by a family of conformers. PONDEROSA incorporates and integrates external software packages (TALOS+, STRIDE and CYANA) to carry out different steps in the structure determination. PONDEROSA implements internal functions that identify and validate NOESY peak assignments and assess the quality of the calculated three-dimensional structure of the protein. The robustness of the analysis results from PONDEROSA's hierarchical processing steps that involve iterative interaction among the internal and external modules. PONDEROSA supports a variety of input formats: SPARKY assignment table (.shifts) and spectrum file formats (.ucsf), XEASY proton file format (.prot), and NMR-STAR format (.star). To demonstrate the utility of PONDEROSA, we used the package to determine 3D structures of two proteins: human ubiquitin and Escherichia coli iron-sulfur scaffold protein variant IscU(D39A). The automatically generated structural constraints and ensembles of conformers were as good as or better than those determined previously by much less automated means. The program, in the form of binary code along with tutorials and reference manuals, is available at http://ponderosa.nmrfam.wisc.edu/.

  13. Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.

    PubMed

    Smart, Oliver S; Womack, Thomas O; Flensburg, Claus; Keller, Peter; Paciorek, Włodek; Sharff, Andrew; Vonrhein, Clemens; Bricogne, Gérard

    2012-04-01

    Maximum-likelihood X-ray macromolecular structure refinement in BUSTER has been extended with restraints facilitating the exploitation of structural similarity. The similarity can be between two or more chains within the structure being refined, thus favouring NCS, or to a distinct 'target' structure that remains fixed during refinement. The local structural similarity restraints (LSSR) approach considers all distances less than 5.5 Å between pairs of atoms in the chain to be restrained. For each, the difference from the distance between the corresponding atoms in the related chain is found. LSSR applies a restraint penalty on each difference. A functional form that reaches a plateau for large differences is used to avoid the restraints distorting parts of the structure that are not similar. Because LSSR are local, there is no need to separate out domains. Some restraint pruning is still necessary, but this has been automated. LSSR have been available to academic users of BUSTER since 2009 with the easy-to-use -autoncs and -target target.pdb options. The use of LSSR is illustrated in the re-refinement of PDB entries 5rnt, where -target enables the correct ligand-binding structure to be found, and 1osg, where -autoncs contributes to the location of an additional copy of the cyclic peptide ligand.

  14. Software design for automated assembly of truss structures

    NASA Technical Reports Server (NTRS)

    Herstrom, Catherine L.; Grantham, Carolyn; Allen, Cheryl L.; Doggett, William R.; Will, Ralph W.

    1992-01-01

    Concern over the limited intravehicular activity time has increased the interest in performing in-space assembly and construction operations with automated robotic systems. A technique being considered at LaRC is a supervised-autonomy approach, which can be monitored by an Earth-based supervisor that intervenes only when the automated system encounters a problem. A test-bed to support evaluation of the hardware and software requirements for supervised-autonomy assembly methods was developed. This report describes the design of the software system necessary to support the assembly process. The software is hierarchical and supports both automated assembly operations and supervisor error-recovery procedures, including the capability to pause and reverse any operation. The software design serves as a model for the development of software for more sophisticated automated systems and as a test-bed for evaluation of new concepts and hardware components.

  15. Tectonic evolution of the Paranoá basin: New evidence from gravimetric and stratigraphic data

    NASA Astrophysics Data System (ADS)

    Martins-Ferreira, Marco Antonio Caçador; Campos, José Eloi Guimarães; Von Huelsen, Monica Giannoccaro

    2018-06-01

    Field gravimetric and stratigraphic surveys were conducted with the aim to constraint the mechanisms responsible for the initiation of the Stenian-Tonian Paranoá basin, central Brazil, a subject not yet studied in detail. The Paranoá Group crops out in the external zone of the Brasília Belt, a Neoproterozoic orogen in the western margin of the São Francisco Craton. Detailed geological mapping confirmed the existence of a regional scale fault that controlled sedimentation of the Paranoá Group during the deposition of its basal formations, revealing important details about basin initiation and early evolution. Gravimetric modeling indicates the existence of paleorift structures beneath the Paranoá sequence in the study area. Results from both stratigraphic and gravimetric surveys show strong evidence of mechanical subsidence by faulting during basin initiation. Unsorted, angular, clasts cut by quartz veins and brecciated boulders present in the basal conglomerate, support this hypothesis. Basin initiation faults coincide with deeper paleorift faults and are thus interpreted as reactivations of the older Statherian Araí Rift. The reactivations favored an initial regime of mechanical subsidence, dominated by the development of epirogenic arches subsiding at different rates. Apart from faulting activity, the post-basal sequence presents no evidence of rift environment in the strict sense. Besides, the great lateral continuity and relatively constant thickness of facies, indicate that an initial mechanic subsidence rapidly gave way to flexural subsidence during subsequent stages of basin evolution. The Paranoá Group do not present reliable characteristics that would allow its strict classification as a passive margin. Its main stratigraphic characteristics, tectonic location and basement architecture, indicate that the Paranoá Group was deposited in a cratonic margin basin, and may have been either connected to a passive margin basin at times of sea level rise

  16. Automated segmentation and recognition of the bone structure in non-contrast torso CT images using implicit anatomical knowledge

    NASA Astrophysics Data System (ADS)

    Zhou, X.; Hayashi, T.; Han, M.; Chen, H.; Hara, T.; Fujita, H.; Yokoyama, R.; Kanematsu, M.; Hoshi, H.

    2009-02-01

    X-ray CT images have been widely used in clinical diagnosis in recent years. A modern CT scanner can generate about 1000 CT slices to show the details of all the human organs within 30 seconds. However, CT image interpretations (viewing 500-1000 slices of CT images manually in front of a screen or films for each patient) require a lot of time and energy. Therefore, computer-aided diagnosis (CAD) systems that can support CT image interpretations are strongly anticipated. Automated recognition of the anatomical structures in CT images is a basic pre-processing of the CAD system. The bone structure is a part of anatomical structures and very useful to act as the landmarks for predictions of the other different organ positions. However, the automated recognition of the bone structure is still a challenging issue. This research proposes an automated scheme for segmenting the bone regions and recognizing the bone structure in noncontrast torso CT images. The proposed scheme was applied to 48 torso CT cases and a subjective evaluation for the experimental results was carried out by an anatomical expert following the anatomical definition. The experimental results showed that the bone structure in 90% CT cases have been recognized correctly. For quantitative evaluation, automated recognition results were compared to manual inputs of bones of lower limb created by an anatomical expert on 10 randomly selected CT cases. The error (maximum distance in 3D) between the recognition results and manual inputs distributed from 3-8 mm in different parts of the bone regions.

  17. A three-dimensional stratigraphic model for aggrading submarine channels based on laboratory experiments, numerical modeling, and sediment cores

    NASA Astrophysics Data System (ADS)

    Limaye, A. B.; Komatsu, Y.; Suzuki, K.; Paola, C.

    2017-12-01

    Turbidity currents deliver clastic sediment from continental margins to the deep ocean, and are the main driver of landscape and stratigraphic evolution in many low-relief, submarine environments. The sedimentary architecture of turbidites—including the spatial organization of coarse and fine sediments—is closely related to the aggradation, scour, and lateral shifting of channels. Seismic stratigraphy indicates that submarine, meandering channels often aggrade rapidly relative to lateral shifting, and develop channel sand bodies with high vertical connectivity. In comparison, the stratigraphic architecture developed by submarine, braided is relatively uncertain. We present a new stratigraphic model for submarine braided channels that integrates predictions from laboratory experiments and flow modeling with constraints from sediment cores. In the laboratory experiments, a saline density current developed subaqueous channels in plastic sediment. The channels aggraded to form a deposit with a vertical scale of approximately five channel depths. We collected topography data during aggradation to (1) establish relative stratigraphic age, and (2) estimate the sorting patterns of a hypothetical grain size distribution. We applied a numerical flow model to each topographic surface and used modeled flow depth as a proxy for relative grain size. We then conditioned the resulting stratigraphic model to observed grain size distributions using sediment core data from the Nankai Trough, offshore Japan. Using this stratigraphic model, we establish new, quantitative predictions for the two- and three-dimensional connectivity of coarse sediment as a function of fine-sediment fraction. Using this case study as an example, we will highlight outstanding challenges in relating the evolution of low-relief landscapes to the stratigraphic record.

  18. Aircraft wing structural design optimization based on automated finite element modelling and ground structure approach

    NASA Astrophysics Data System (ADS)

    Yang, Weizhu; Yue, Zhufeng; Li, Lei; Wang, Peiyan

    2016-01-01

    An optimization procedure combining an automated finite element modelling (AFEM) technique with a ground structure approach (GSA) is proposed for structural layout and sizing design of aircraft wings. The AFEM technique, based on CATIA VBA scripting and PCL programming, is used to generate models automatically considering the arrangement of inner systems. GSA is used for local structural topology optimization. The design procedure is applied to a high-aspect-ratio wing. The arrangement of the integral fuel tank, landing gear and control surfaces is considered. For the landing gear region, a non-conventional initial structural layout is adopted. The positions of components, the number of ribs and local topology in the wing box and landing gear region are optimized to obtain a minimum structural weight. Constraints include tank volume, strength, buckling and aeroelastic parameters. The results show that the combined approach leads to a greater weight saving, i.e. 26.5%, compared with three additional optimizations based on individual design approaches.

  19. Mass Spectra-Based Framework for Automated Structural Elucidation of Metabolome Data to Explore Phytochemical Diversity

    PubMed Central

    Matsuda, Fumio; Nakabayashi, Ryo; Sawada, Yuji; Suzuki, Makoto; Hirai, Masami Y.; Kanaya, Shigehiko; Saito, Kazuki

    2011-01-01

    A novel framework for automated elucidation of metabolite structures in liquid chromatography–mass spectrometer metabolome data was constructed by integrating databases. High-resolution tandem mass spectra data automatically acquired from each metabolite signal were used for database searches. Three distinct databases, KNApSAcK, ReSpect, and the PRIMe standard compound database, were employed for the structural elucidation. The outputs were retrieved using the CAS metabolite identifier for identification and putative annotation. A simple metabolite ontology system was also introduced to attain putative characterization of the metabolite signals. The automated method was applied for the metabolome data sets obtained from the rosette leaves of 20 Arabidopsis accessions. Phenotypic variations in novel Arabidopsis metabolites among these accessions could be investigated using this method. PMID:22645535

  20. Characterizing Structural and Stratigraphic Heterogeneities in a Faulted Aquifer Using Pump Tests with an Array of Westbay Multilevel Monitoring Wells

    NASA Astrophysics Data System (ADS)

    Johnson, B.; Zhurina, E. N.

    2001-12-01

    We are developing and assessing field testing and analysis methodologies for quantitative characterization of aquifer heterogenities using data measured in an array of multilevel monitoring wells (MLW) during pumping and recovery well tests. We have developed a unique field laboratory to determine the permeability field in a 20m by 40m by 70m volume in the fault partitioned, siliciclastic Hickory aquifer system in central Texas. The site incorporates both stratigraphic variations and a normal fault system that partially offsets the aquifer and impedes cross-fault flow. We constructed a high-resolution geologic model of the site based upon 1050 m of core and a suite of geophysical logs from eleven, closely spaced (3-10m), continuously cored boreholes to depths of 125 m. Westbay multilevel monitoring systems installed in eight holes provide 94 hydraulically isolated measurement zones and 25 injection zones. A good geologic model is critical to proper installation of the MLW. Packers are positioned at all significant fault piercements and selected, laterally extensive, clay-rich strata. Packers in adjacent MLW bracket selected hydrostratigraphic intervals. Pump tests utilized two, uncased, fully penetrating irrigation wells that straddle the fault system and are in close proximity (7 to 65 m) to the MLW. Pumping and recovery transient pressure histories were measured in 85 zones using pressure transducers with a resolution of 55 Pa (0.008 psi). The hydraulic response is that of an anisotropic, unconfined aquifer. The transient pressure histories vary significantly from zone to zone in a single MLW as well as between adjacent MLW. Derivative plots are especially useful for differentiating details of pressure histories. Based on the geologic model, the derivative curve of a zone reflects its absolute vertical position, vertical stratigraphic position, and proximity to either a fault or significant stratigraphic heterogeneity. Additional forward modeling is needed to

  1. A MATLAB®-based program for 3D visualization of stratigraphic setting and subsidence evolution of sedimentary basins: example application to the Vienna Basin

    NASA Astrophysics Data System (ADS)

    Lee, Eun Young; Novotny, Johannes; Wagreich, Michael

    2015-04-01

    In recent years, 3D visualization of sedimentary basins has become increasingly popular. Stratigraphic and structural mapping is highly important to understand the internal setting of sedimentary basins. And subsequent subsidence analysis provides significant insights for basin evolution. This study focused on developing a simple and user-friendly program which allows geologists to analyze and model sedimentary basin data. The developed program is aimed at stratigraphic and subsidence modelling of sedimentary basins from wells or stratigraphic profile data. This program is mainly based on two numerical methods; surface interpolation and subsidence analysis. For surface visualization four different interpolation techniques (Linear, Natural, Cubic Spline, and Thin-Plate Spline) are provided in this program. The subsidence analysis consists of decompaction and backstripping techniques. The numerical methods are computed in MATLAB® which is a multi-paradigm numerical computing environment used extensively in academic, research, and industrial fields. This program consists of five main processing steps; 1) setup (study area and stratigraphic units), 2) loading of well data, 3) stratigraphic modelling (depth distribution and isopach plots), 4) subsidence parameter input, and 5) subsidence modelling (subsided depth and subsidence rate plots). The graphical user interface intuitively guides users through all process stages and provides tools to analyse and export the results. Interpolation and subsidence results are cached to minimize redundant computations and improve the interactivity of the program. All 2D and 3D visualizations are created by using MATLAB plotting functions, which enables users to fine-tune the visualization results using the full range of available plot options in MATLAB. All functions of this program are illustrated with a case study of Miocene sediments in the Vienna Basin. The basin is an ideal place to test this program, because sufficient data is

  2. The Anthropocene is functionally and stratigraphically distinct from the Holocene.

    PubMed

    Waters, Colin N; Zalasiewicz, Jan; Summerhayes, Colin; Barnosky, Anthony D; Poirier, Clément; Gałuszka, Agnieszka; Cearreta, Alejandro; Edgeworth, Matt; Ellis, Erle C; Ellis, Michael; Jeandel, Catherine; Leinfelder, Reinhold; McNeill, J R; Richter, Daniel deB; Steffen, Will; Syvitski, James; Vidas, Davor; Wagreich, Michael; Williams, Mark; Zhisheng, An; Grinevald, Jacques; Odada, Eric; Oreskes, Naomi; Wolfe, Alexander P

    2016-01-08

    Human activity is leaving a pervasive and persistent signature on Earth. Vigorous debate continues about whether this warrants recognition as a new geologic time unit known as the Anthropocene. We review anthropogenic markers of functional changes in the Earth system through the stratigraphic record. The appearance of manufactured materials in sediments, including aluminum, plastics, and concrete, coincides with global spikes in fallout radionuclides and particulates from fossil fuel combustion. Carbon, nitrogen, and phosphorus cycles have been substantially modified over the past century. Rates of sea-level rise and the extent of human perturbation of the climate system exceed Late Holocene changes. Biotic changes include species invasions worldwide and accelerating rates of extinction. These combined signals render the Anthropocene stratigraphically distinct from the Holocene and earlier epochs. Copyright © 2016, American Association for the Advancement of Science.

  3. The rock components and structures of Archean greenstone belts: An overview

    NASA Technical Reports Server (NTRS)

    Lowe, D. R.; Byerly, G. R.

    1986-01-01

    Knowledge of the character and evolution of the Earth's early crust is derived from the studies of the rocks and structures in Archean greenstone belts. Ability to resolve the petrologic, sedimentological and structural histories of greenstone belts, however, hinges first on an ability to apply the concepts and procedures of classical stratigraphy. Unfortunately, early Precambrian greenstone terrains present particular problems to stratigraphic analysis. Many current controversies of greenstone belt petrogenesis, sedimentology, tectonics and evolution arise more from an inability to develop a clear stratigraphic picture of the belts than from ambiguities in interpretation. Four particular stratigraphic problems that afflict studies of Archean greenstone belts are considered: determination of facing directions, correlation of lithologic units, identification of primary lithologies and discrimination of stratigraphic versus structural contacts.

  4. NACSN, note 67--Application for revision of Articles 36 and 37, Lithodemic units of the North American stratigraphic code

    USGS Publications Warehouse

    Easton, Robert M.; Edwards, Lucy E.; Orndorff, Randall C.; Duguet, Manuel; Ferrusquia-Villafranca, Ismael

    2015-01-01

    Currently the North American Stratigraphic Code, (NACSN 2005, Article 37) sets restrictions on the use of the term “complex” for lithodemic units. With exceptions for “volcanic complex” and “structural complex,” a complex must consist of more than one genetic class of rock (i.e., sedimentary, igneous or metamorphic). Thus, the use of the term “complex” to describe masses of intrusive rocks is not allowed. Asimilar restriction is also included in a recent British Geological Survey proposal for using lithodemic units to classify igneous rocks (Gillespie et al. 2008).Currently the North American Stratigraphic Code, (NACSN 2005, Article 37) sets restrictions on the use of the term “complex” for lithodemic units. With exceptions for “volcanic complex” and “structural complex,” a complex must consist of more than one genetic class of rock (i.e., sedimentary, igneous or metamorphic). Thus, the use of the term “complex” to describe masses of intrusive rocks is not allowed. Asimilar restriction is also included in a recent British Geological Survey proposal for using lithodemic units to classify igneous rocks (Gillespie et al. 2008).

  5. Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

    PubMed Central

    Smart, Oliver S.; Womack, Thomas O.; Flensburg, Claus; Keller, Peter; Paciorek, Włodek; Sharff, Andrew; Vonrhein, Clemens; Bricogne, Gérard

    2012-01-01

    Maximum-likelihood X-ray macromolecular structure refinement in BUSTER has been extended with restraints facilitating the exploitation of structural similarity. The similarity can be between two or more chains within the structure being refined, thus favouring NCS, or to a distinct ‘target’ structure that remains fixed during refinement. The local structural similarity restraints (LSSR) approach considers all distances less than 5.5 Å between pairs of atoms in the chain to be restrained. For each, the difference from the distance between the corresponding atoms in the related chain is found. LSSR applies a restraint penalty on each difference. A functional form that reaches a plateau for large differences is used to avoid the restraints distorting parts of the structure that are not similar. Because LSSR are local, there is no need to separate out domains. Some restraint pruning is still necessary, but this has been automated. LSSR have been available to academic users of BUSTER since 2009 with the easy-to-use -autoncs and -­target target.pdb options. The use of LSSR is illustrated in the re-refinement of PDB entries 5rnt, where -target enables the correct ligand-binding structure to be found, and 1osg, where -autoncs contributes to the location of an additional copy of the cyclic peptide ligand. PMID:22505257

  6. PONDEROSA, an automated 3D-NOESY peak picking program, enables automated protein structure determination

    PubMed Central

    Lee, Woonghee; Kim, Jin Hae; Westler, William M.; Markley, John L.

    2011-01-01

    Summary: PONDEROSA (Peak-picking Of Noe Data Enabled by Restriction of Shift Assignments) accepts input information consisting of a protein sequence, backbone and sidechain NMR resonance assignments, and 3D-NOESY (13C-edited and/or 15N-edited) spectra, and returns assignments of NOESY crosspeaks, distance and angle constraints, and a reliable NMR structure represented by a family of conformers. PONDEROSA incorporates and integrates external software packages (TALOS+, STRIDE and CYANA) to carry out different steps in the structure determination. PONDEROSA implements internal functions that identify and validate NOESY peak assignments and assess the quality of the calculated three-dimensional structure of the protein. The robustness of the analysis results from PONDEROSA's hierarchical processing steps that involve iterative interaction among the internal and external modules. PONDEROSA supports a variety of input formats: SPARKY assignment table (.shifts) and spectrum file formats (.ucsf), XEASY proton file format (.prot), and NMR-STAR format (.star). To demonstrate the utility of PONDEROSA, we used the package to determine 3D structures of two proteins: human ubiquitin and Escherichia coli iron-sulfur scaffold protein variant IscU(D39A). The automatically generated structural constraints and ensembles of conformers were as good as or better than those determined previously by much less automated means. Availability: The program, in the form of binary code along with tutorials and reference manuals, is available at http://ponderosa.nmrfam.wisc.edu/. Contact: whlee@nmrfam.wisc.edu; markley@nmrfam.wisc.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:21511715

  7. Automated segmentation of pulmonary structures in thoracic computed tomography scans: a review

    NASA Astrophysics Data System (ADS)

    van Rikxoort, Eva M.; van Ginneken, Bram

    2013-09-01

    Computed tomography (CT) is the modality of choice for imaging the lungs in vivo. Sub-millimeter isotropic images of the lungs can be obtained within seconds, allowing the detection of small lesions and detailed analysis of disease processes. The high resolution of thoracic CT and the high prevalence of lung diseases require a high degree of automation in the analysis pipeline. The automated segmentation of pulmonary structures in thoracic CT has been an important research topic for over a decade now. This systematic review provides an overview of current literature. We discuss segmentation methods for the lungs, the pulmonary vasculature, the airways, including airway tree construction and airway wall segmentation, the fissures, the lobes and the pulmonary segments. For each topic, the current state of the art is summarized, and topics for future research are identified.

  8. 3D seismic investigation of the structural and stratigraphic characteristics of the Pagasa Wedge, Southwest Palawan Basin, Philippines, and their tectonic implications

    NASA Astrophysics Data System (ADS)

    Ilao, Kimberly A.; Morley, Christopher K.; Aurelio, Mario A.

    2018-04-01

    The Pagasa Wedge is a poorly imaged deepwater orogenic wedge that has been variously interpreted as representing an accretionary prism, a former accretionary prism modified by thrusting onto a thinned continental margin, and a gravity-driven fold-thrust belt. This study, using 2D and 3D seismic data, together with well information indicates that at least the external part of the wedge is dominantly composed of mass transport complexes, capped by syn-kinematic sediments that have thrusts and normal faults superimposed upon them. Drilling shows that despite stratigraphic repetition of Eocene Middle Miocene units, there is stratigraphic omission of Oligocene and Early Miocene units. This absence suggests that mass transport processes have introduced the Eocene section into the wedge rather than tectonic thrusting. The accretionary prism stage (Oligocene) of the Central Palawan Ophiolite history appears to be marked by predominantly north-vergent deformation. The Deep Regional Unconformity (∼17 Ma) likely indicates the approximate time when obduction ceased in Palawan. The Pagasa Wedge is a late-stage product of the convergence history that was active in its final phase sometime above the top of the Nido Limestone (∼16 Ma) and the base of the Tabon Limestone in the Aboabo-A1X well (∼9 Ma). The top of the wedge is traditionally associated with the Middle Miocene Unconformity (MMU), However the presence of multiple unconformities, diachronous formation tops, local tectonic unconformities and regional diachronous events (e.g. migrating forebulges) all suggest simply giving a single age (or assigning a single unconformity, such as the MMU as defining the top of the Pagasa Wedge is inappropriate. The overall NE-SW trend of the wedge, and the dominant NW transport of structures within the wedge diverge from the more northerly transport direction determined from outcrops in Palawan, and also from the Nido Limestone in the SW part of the Pagasa Wedge. Possibly this NW

  9. Arctic ice shelves and ice islands: Origin, growth and disintegration, physical characteristics, structural-stratigraphic variability, and dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jeffries, M.O.

    1992-08-01

    Ice shelves are thick, floating ice masses most often associated with Antarctica where they are seaward extensions of the grounded Antarctic ice sheet and sources of many icebergs. However, there are also ice shelves in the Arctic, primarily located along the north coast of Ellesmere Island in the Canadian High Arctic. The only ice shelves in North America and the most extensive in the north polar region, the Ellesmere ice shelves originate from glaciers and from sea ice and are the source of ice islands, the tabular icebergs of the Arctic Ocean. The present state of knowledge and understanding ofmore » these ice features is summarized in this paper. It includes historical background to the discovery and early study of ice shelves and ice islands, including the use of ice islands as floating laboratories for polar geophysical research. Growth mechanisms and age, the former extent and the twentieth century disintegration of the Ellesmere ice shelves, and the processes and mechanisms of ice island calving are summarized. Surface features, thickness, thermal regime, and the size, shape, and numbers of ice islands are discussed. The structural-stratigraphic variability of ice islands and ice shelves and the complex nature of their growth and development are described. Large-scale and small-scale dynamics of ice islands are described, and the results of modeling their drift and recurrence intervals are presented. The conclusion identifies some unanswered questions and future research opportunities and needs. 97 refs., 18 figs.« less

  10. Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smart, Oliver S., E-mail: osmart@globalphasing.com; Womack, Thomas O.; Flensburg, Claus

    2012-04-01

    Local structural similarity restraints (LSSR) provide a novel method for exploiting NCS or structural similarity to an external target structure. Two examples are given where BUSTER re-refinement of PDB entries with LSSR produces marked improvements, enabling further structural features to be modelled. Maximum-likelihood X-ray macromolecular structure refinement in BUSTER has been extended with restraints facilitating the exploitation of structural similarity. The similarity can be between two or more chains within the structure being refined, thus favouring NCS, or to a distinct ‘target’ structure that remains fixed during refinement. The local structural similarity restraints (LSSR) approach considers all distances less thanmore » 5.5 Å between pairs of atoms in the chain to be restrained. For each, the difference from the distance between the corresponding atoms in the related chain is found. LSSR applies a restraint penalty on each difference. A functional form that reaches a plateau for large differences is used to avoid the restraints distorting parts of the structure that are not similar. Because LSSR are local, there is no need to separate out domains. Some restraint pruning is still necessary, but this has been automated. LSSR have been available to academic users of BUSTER since 2009 with the easy-to-use -autoncs and @@target target.pdb options. The use of LSSR is illustrated in the re-refinement of PDB entries http://scripts.iucr.org/cgi-bin/cr.cgi?rm, where -target enables the correct ligand-binding structure to be found, and http://scripts.iucr.org/cgi-bin/cr.cgi?rm, where -autoncs contributes to the location of an additional copy of the cyclic peptide ligand.« less

  11. Types of stratigraphic traps in Lower Cretaceous Muddy Formation, northern Powder River Basin, Wyoming

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lovekin, J.R.; Odland, S.K.; Quartarone, T.S. Gardner, M.H.

    1986-08-01

    Stratigraphic traps account for most of the oil produced from the Muddy Sandstone in the northern Powder River basin. Two categories of traps exist. The first trap type is the result of lateral and vertical facies changes. Reservoir facies include tidal channels, point bars, bayhead deltas, barrier islands, and strand-plain sandstones; trapping facies include bay-fill and estuarine sediments, mud-filled tidal channels, and flood-plain deposits. The second of the two categories of traps results from an unconformity that juxtaposes permeable and impermeable sediments of quite different ages. Structural and diagenetic factors often modify and locally enhance reservoir quality within both categoriesmore » of stratigraphic traps. The various types of traps are demonstrated by studies of six field areas: (1) barrier-island sandstones, sealed updip by back-barrier shales, produce at Ute and Kitty fields; (2) tidal channels produce at Collums and Kitty fields; (3) bayhead deltas, encased in estuarine sediments, form traps at Oedekoven and Kitty fields; (4) fluvial point-bar sandstones form traps at Oedekoven, Store, and Kitty fields; (5) unconformity-related traps exist where Muddy fluvial valley-fill sediments lap out against impermeable valley walls of Skull Creek Shale on the updip side at Store, Oedekoven, and Kitty fields; and (6) the clay-rich weathered zone, directly beneath an intraformational unconformity, forms the seal to the reservoirs at Amos Draw field.« less

  12. Automated sub-cortical brain structure segmentation combining spatial and deep convolutional features.

    PubMed

    Kushibar, Kaisar; Valverde, Sergi; González-Villà, Sandra; Bernal, Jose; Cabezas, Mariano; Oliver, Arnau; Lladó, Xavier

    2018-06-15

    Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time as morphological changes in these structures are related to different neurodegenerative disorders. However, manual segmentation of these structures can be tedious and prone to variability, highlighting the need for robust automated segmentation methods. In this paper, we present a novel convolutional neural network based approach for accurate segmentation of the sub-cortical brain structures that combines both convolutional and prior spatial features for improving the segmentation accuracy. In order to increase the accuracy of the automated segmentation, we propose to train the network using a restricted sample selection to force the network to learn the most difficult parts of the structures. We evaluate the accuracy of the proposed method on the public MICCAI 2012 challenge and IBSR 18 datasets, comparing it with different traditional and deep learning state-of-the-art methods. On the MICCAI 2012 dataset, our method shows an excellent performance comparable to the best participant strategy on the challenge, while performing significantly better than state-of-the-art techniques such as FreeSurfer and FIRST. On the IBSR 18 dataset, our method also exhibits a significant increase in the performance with respect to not only FreeSurfer and FIRST, but also comparable or better results than other recent deep learning approaches. Moreover, our experiments show that both the addition of the spatial priors and the restricted sampling strategy have a significant effect on the accuracy of the proposed method. In order to encourage the reproducibility and the use of the proposed method, a public version of our approach is available to download for the neuroimaging community. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  13. Sequence stratigraphy in the middle Ordovician shale successions, mid-east Korea: Stratigraphic variations and preservation potential of organic matter within a sequence stratigraphic framework

    NASA Astrophysics Data System (ADS)

    Byun, Uk Hwan; Lee, Hyun Suk; Kwon, Yi Kyun

    2018-02-01

    The Jigunsan Formation is the middle Ordovician shale-dominated transgressive succession in the Taebaeksan Basin, located in the eastern margin of the North China platform. The total organic carbon (TOC) content and some geochemical properties of the succession exhibit a stratigraphically distinct distribution pattern. The pattern was closely associated with the redox conditions related to decomposition, bulk sedimentation rate (dilution), and productivity. To explain the distinct distribution pattern, this study attempted to construct a high-resolution sequence stratigraphic framework for the Jigunsan Formation. The shale-dominated Jigunsan Formation comprises a lower layer of dark gray shale, deposited during transgression, and an upper layer of greenish gray siltstone, deposited during highstand and falling stage systems tracts. The concept of a back-stepped carbonate platform is adopted to distinguish early and late transgressive systems tracts (early and late TST) in this study, whereas the highstand systems tracts and falling stage systems tracts can be divided by changes in stacking patterns from aggradation to progradation. The late TST would be initiated on a rapidly back-stepping surface of sediments and, just above the surface, exhibits a high peak in TOC content, followed by a gradually upward decrease. This trend of TOC distribution in the late TST continues to the maximum flooding surface (MFS). The perplexing TOC distribution pattern within the late TST most likely resulted from both a gradual reduction in productivity during the late TST and a gradual increase in dilution effect near the MFS interval. The reduced production of organic matter primarily incurred decreasing TOC content toward the MFS when the productivity was mainly governed by benthic biota because planktonic organisms were not widespread in the Ordovician. Results of this study will help improve the understanding of the source rock distribution in mixed carbonate

  14. Revised Cretaceous and Tertiary stratigraphic nomenclature in the Colville Basin, Northern Alaska

    USGS Publications Warehouse

    Mull, Charles G.; Houseknecht, David W.; Bird, Kenneth J.

    2003-01-01

    A revised stratigraphic nomenclature is proposed for Cretaceous and Tertiary geologic units of the central and western North Slope of Alaska. This revised nomenclature is a simplified and broadly applicable scheme suitable for a suite of digital geologic quadrangle maps being prepared jointly by the U.S. Geological Survey and the Alaska Department of Natural Resources, Division of Geological and Geophysical Surveys and Division of Oil and Gas. This revised nomenclature scheme is a simplification of a complex stratigraphic terminology that developed piecemeal during five decades of geologic investigations of the North Slope. It is based on helicopter-supported geologic field investigations incorporating information from high-resolution aerial photography, satellite imagery, paleontology, reflection seismic records, and sequence stratigraphic concepts. This revised nomenclature proposes the abandonment of the Colville Group; demotion of the Nanushuk Group to formation status; abandonment of six formations (Kukpowruk, Tuktu, Grandstand, Corwin, Chandler, and Ninuluk); revision of four formations (Sagavanirktok, Prince Creek, Schrader Bluff, and Seabee); elevation of the Tuluvak Tongue of the Prince Creek Formation to formation status; revision of two members (Franklin Bluffs Member and Sagwon Member of the Sagavanirktok Formation); abandonment of eight members or tongues (Kogosukruk, Rogers Creek, Barrow Trail, Sentinel Hill, Ayiyak, Shale Wall, Niakogon, and Killik); and definition of one new member (White Hills Member of the Sagavanirktok Formation).

  15. The Upgrade Programme for the Structural Biology beamlines at the European Synchrotron Radiation Facility - High throughput sample evaluation and automation

    NASA Astrophysics Data System (ADS)

    Theveneau, P.; Baker, R.; Barrett, R.; Beteva, A.; Bowler, M. W.; Carpentier, P.; Caserotto, H.; de Sanctis, D.; Dobias, F.; Flot, D.; Guijarro, M.; Giraud, T.; Lentini, M.; Leonard, G. A.; Mattenet, M.; McCarthy, A. A.; McSweeney, S. M.; Morawe, C.; Nanao, M.; Nurizzo, D.; Ohlsson, S.; Pernot, P.; Popov, A. N.; Round, A.; Royant, A.; Schmid, W.; Snigirev, A.; Surr, J.; Mueller-Dieckmann, C.

    2013-03-01

    Automation and advances in technology are the key elements in addressing the steadily increasing complexity of Macromolecular Crystallography (MX) experiments. Much of this complexity is due to the inter-and intra-crystal heterogeneity in diffraction quality often observed for crystals of multi-component macromolecular assemblies or membrane proteins. Such heterogeneity makes high-throughput sample evaluation an important and necessary tool for increasing the chances of a successful structure determination. The introduction at the ESRF of automatic sample changers in 2005 dramatically increased the number of samples that were tested for diffraction quality. This "first generation" of automation, coupled with advances in software aimed at optimising data collection strategies in MX, resulted in a three-fold increase in the number of crystal structures elucidated per year using data collected at the ESRF. In addition, sample evaluation can be further complemented using small angle scattering experiments on the newly constructed bioSAXS facility on BM29 and the micro-spectroscopy facility (ID29S). The construction of a second generation of automated facilities on the MASSIF (Massively Automated Sample Screening Integrated Facility) beam lines will build on these advances and should provide a paradigm shift in how MX experiments are carried out which will benefit the entire Structural Biology community.

  16. Stratigraphic and palaeoenvironmental summary of the south-east Georgia Embayment: a correlation of exploratory wells

    USGS Publications Warehouse

    Poppe, L.J.; Popenoe, P.; Poag, C.W.; Swift, B.A.

    1995-01-01

    A Continental Offshore Stratigraphic Test (COST) well and six exploratory wells have been drilled in the south-east Georgia embayment. The oldest rocks penetrated are weakly metamorphosed Lower Ordovician quartz arenites and Silurian shales and argillites in the Transco 1005-1 well and Upper Devonian argillites in the COST GE-1 well. The Palaeozoic strata are unconformably overlain by interbedded non-marine Jurassic sandstones and shales and marginal marine Lower Cretaceous rocks. Together, these rocks are stratigraphically equivalent to the onshore Fort Pierce and Cotton Valley(?) Formations and rocks of the Lower Cretaceous Comanchean Provincial Series. The Upper Cretaceous part of the section is composed mainly of neritic calcareous shales and shaley limestones stratigraphically equivalent to the primarily marginal marine facies of the onshore Atkinson, Cape Fear and Middendorf Formations and Black Creek Group, and to limestones and shales of the Lawson Limestone and Peedee Formations. Cenozoic strata are also described. -from Authors

  17. Modeling Stratigraphic Architecture of Deep-water Deposits Using a Small Unmanned Aircraft: Neogene Thin-bedded Turbidites, East Coast Basin, New Zealand

    NASA Astrophysics Data System (ADS)

    Nieminski, N.; Graham, S. A.

    2014-12-01

    One of the outstanding challenges of field geology is inaccessibility of exposure. The ability to view and characterize outcrops that are difficult to study from the ground is greatly improved by aerial investigation. Detailed stratigraphic architecture of such exposures is best addressed by using advances and availability of small unmanned aircraft systems (sUAS) that can safely navigate from high-altitude overviews of study areas to within a meter of the exposure of interest. High-resolution photographs acquired at various elevations and azimuths by sUAS are then used to convert field measurements to digital representations in three-dimensions at a fine scale. Photogrammetric software is used to capture complex, detailed topography by creating digital surface models with a range imaging technique that estimates three-dimensional structures from two-dimensional image sequences. The digital surface model is overlain by detailed, high-resolution photography. Pairing sUAS technology with readily available photogrammetry software that requires little processing time and resources offers a revolutionary and cost-effective methodology for geoscientists to investigate and quantify stratigraphic and structural complexity of field studies from the convenience of the office. These methods of imaging and modeling remote outcrops are demonstrated in the East Coast Basin, New Zealand, where wave-cut platform exposures of Miocene deep-water deposits offer a unique opportunity to investigate the flow processes and resulting characteristics of thin-bedded turbidite deposits. Stratigraphic architecture of wavecut platform and vertically-dipping exposures of these thin-bedded turbidites is investigated with sUAS coupled with Structure from Motion (SfM) photogrammetry software. This approach allows the geometric and spatial variation of deep-water architecture to be characterized continuously along 2,000 meters of lateral exposure, as well as to measure and quantify cyclic

  18. Pricing Structures for Automated Library Consortia.

    ERIC Educational Resources Information Center

    Machovec, George S.

    1993-01-01

    Discusses the development of successful pricing algorithms for cooperative library automation projects. Highlights include desirable characteristics of pricing measures, including simplicity and the ability to allow for system growth; problems with transaction-based systems; and a review of the pricing strategies of seven library consortia.…

  19. Stratigraphic variations in the Carboniferous section across the Arkansas-Oklahoma State Line Arch

    NASA Astrophysics Data System (ADS)

    Engelhardt, Tyler D.

    The State Line Arch is represented by a structural high that trends through the study area in a loose alignment with the Arkansas-Oklahoma state line. Evidence of the arch extending further to the north includes a structural high and stratigraphic variation at an outcrop on Highway 59 near Evansville Mountain in Crawford County, Arkansas. The exact timing of the formation of the arch remains undetermined, but upper Devonian thinning at the top of the arch indicates the structure is pre-Mississippian. The reason for the development of the arch is poorly understood, but evidence linking Mississippian-aged Waulsortian mounds to Precambrian Spavinaw granite structures of northeastern Oklahoma and southwestern Missouri suggests Precambrian basement structures may extend into the study area. The structural nature of the arch provided an environment favorable to carbonate build-up during deposition of the Mississippian interval. A previously unidentified limestone unit measuring 175 feet thick likely represents the transgressive phase of a transgressive-regressive sequence responsible for the deposition of the Mayes Group of northeastern Oklahoma. Growth on the downthrown side of the Muldrow-Mulberry Fault system may indicate earlier movement than previous studies have suggested on the east-west trending normal faults of the Arkoma Basin. A possible roll-over anticline structure may exist to the south of the Muldrow-Mulberry fault system.

  20. Stratigraphic comparison of six oil fields (WV) producing from Big Injun sandstones

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zou, X.; Donaldson, A.C.

    1993-08-01

    Clustered within western West Virginia, six oil fields produce from the lower Mississippian Big Injun sandstones, and three more oil fields also supplement this production either from underlying Squaw or Weir sandstones. Shales separate these sandstones that occur stratigraphically between the Sunbury Shale (maximum flooding surface) and pre-Greenbrier unconformity (maximum regressive erosional surface), and represent highstand regressive deposits associated with the postorogenic phase of foreland basin accumulation. Stratigraphic studies show two Big Injun sandstones. The upper sandstone, called the Maccrady Big Injun, is separated from the lower Price/Pocono Big Injun sandstone by red shales. Both Big Injun sandstones consist ofmore » fine-grained river-mouth bars capped by coarse-grained river-channel deposits. Although the six fields are within three adjacent counties, Maccrady Big Injun sandstones of Blue Creek (Kanawha) and Rock Creek (Roane) fields are younger and were deposited by a different fluvial-deltaic system than the Price/Pocono Big Injun sandstones of Granny Creek (Clay), Tariff (Roane) Clendenin (Clay), and Pond Fork (Kanawha) fields. Upper Weir sandstones are thick, narrow north-trending belts underlying Pond Fork and Blue Creek fields, with properties suggesting wave-dominated shoreline deposits. Allocycles spanning separate drainage systems indicate eustasy. Postorogenic flexural adjustments probably explain stacked sandstone belts with superposed paleovalleys of overlying unconformities (pre-Greenbrier, Pottsville), particularly where aligned along or parallel basement structures of Rome trough or West Virginia dome. Initially, differential subsidence or uplift during sedimentation influenced the position, geometry, trend, and distribution patterns of these reservoir sandstone, then influenced their preserved condition during erosion of pre-Greenbrier unconformity.« less

  1. Early evolution of the southern margin of the Neuquén Basin, Argentina: Tectono-stratigraphic implications for rift evolution and exploration of hydrocarbon plays

    NASA Astrophysics Data System (ADS)

    D'Elia, Leandro; Bilmes, Andrés; Franzese, Juan R.; Veiga, Gonzalo D.; Hernández, Mariano; Muravchik, Martín

    2015-12-01

    Long-lived rift basins are characterized by a complex structural and tectonic evolution. They present significant lateral and vertical stratigraphic variations that determine diverse basin-patterns at different timing, scale and location. These issues cause difficulties to establish facies models, correlations and stratal stacking patterns of the fault-related stratigraphy, specially when exploration of hydrocarbon plays proceeds on the subsurface of a basin. The present case study corresponds to the rift-successions of the Neuquén Basin. This basin formed in response to continental extension that took place at the western margin of Gondwana during the Late Triassic-Early Jurassic. A tectono-stratigraphic analysis of the initial successions of the southern part of the Neuquén Basin was carried out. Three syn-rift sequences were determined. These syn-rift sequences were located in different extensional depocentres during the rifting phases. The specific periods of rifting show distinctly different structural and stratigraphic styles: from non-volcanic to volcanic successions and/or from continental to marine sedimentation. The results were compared with surface and subsurface interpretations performed for other depocentres of the basin, devising an integrated rifting scheme for the whole basin. The more accepted tectono-stratigraphic scheme that assumes the deposits of the first marine transgression (Cuyo Cycle) as indicative of the onset of a post-rift phase is reconsidered. In the southern part of the basin, the marine deposits (lower Cuyo Cycle) were integrated into the syn-rift phase, implying the existence of different tectonic signatures for Cuyo Cycle along the basin. The rift climax becomes younger from north to south along the basin. The post-rift initiation followed the diachronic ending of the main syn-rift phase throughout the Neuquén Basin. Thus, initiation of the post-rift stage started in the north and proceeded towards the south, constituting a

  2. Automated design optimization of supersonic airplane wing structures under dynamic constraints

    NASA Technical Reports Server (NTRS)

    Fox, R. L.; Miura, H.; Rao, S. S.

    1972-01-01

    The problems of the preliminary and first level detail design of supersonic aircraft wings are stated as mathematical programs and solved using automated optimum design techniques. The problem is approached in two phases: the first is a simplified equivalent plate model in which the envelope, planform and structural parameters are varied to produce a design, the second is a finite element model with fixed configuration in which the material distribution is varied. Constraints include flutter, aeroelastically computed stresses and deflections, natural frequency and a variety of geometric limitations.

  3. Revised geochronology, correlation, and dinosaur stratigraphic ranges of the Santonian-Maastrichtian (Late Cretaceous) formations of the Western Interior of North America

    PubMed Central

    Fowler, Denver Warwick

    2017-01-01

    Interbasinal stratigraphic correlation provides the foundation for all consequent continental-scale geological and paleontological analyses. Correlation requires synthesis of lithostratigraphic, biostratigraphic and geochronologic data, and must be periodically updated to accord with advances in dating techniques, changing standards for radiometric dates, new stratigraphic concepts, hypotheses, fossil specimens, and field data. Outdated or incorrect correlation exposes geological and paleontological analyses to potential error. The current work presents a high-resolution stratigraphic chart for terrestrial Late Cretaceous units of North America, combining published chronostratigraphic, lithostratigraphic, and biostratigraphic data. 40Ar / 39Ar radiometric dates are newly recalibrated to both current standard and decay constant pairings. Revisions to the stratigraphic placement of most units are slight, but important changes are made to the proposed correlations of the Aguja and Javelina formations, Texas, and recalibration corrections in particular affect the relative age positions of the Belly River Group, Alberta; Judith River Formation, Montana; Kaiparowits Formation, Utah; and Fruitland and Kirtland formations, New Mexico. The stratigraphic ranges of selected clades of dinosaur species are plotted on the chronostratigraphic framework, with some clades comprising short-duration species that do not overlap stratigraphically with preceding or succeeding forms. This is the expected pattern that is produced by an anagenetic mode of evolution, suggesting that true branching (speciation) events were rare and may have geographic significance. The recent hypothesis of intracontinental latitudinal provinciality of dinosaurs is shown to be affected by previous stratigraphic miscorrelation. Rapid stepwise acquisition of display characters in many dinosaur clades, in particular chasmosaurine ceratopsids, suggests that they may be useful for high resolution biostratigraphy

  4. Revised geochronology, correlation, and dinosaur stratigraphic ranges of the Santonian-Maastrichtian (Late Cretaceous) formations of the Western Interior of North America.

    PubMed

    Fowler, Denver Warwick

    2017-01-01

    Interbasinal stratigraphic correlation provides the foundation for all consequent continental-scale geological and paleontological analyses. Correlation requires synthesis of lithostratigraphic, biostratigraphic and geochronologic data, and must be periodically updated to accord with advances in dating techniques, changing standards for radiometric dates, new stratigraphic concepts, hypotheses, fossil specimens, and field data. Outdated or incorrect correlation exposes geological and paleontological analyses to potential error. The current work presents a high-resolution stratigraphic chart for terrestrial Late Cretaceous units of North America, combining published chronostratigraphic, lithostratigraphic, and biostratigraphic data. 40Ar / 39Ar radiometric dates are newly recalibrated to both current standard and decay constant pairings. Revisions to the stratigraphic placement of most units are slight, but important changes are made to the proposed correlations of the Aguja and Javelina formations, Texas, and recalibration corrections in particular affect the relative age positions of the Belly River Group, Alberta; Judith River Formation, Montana; Kaiparowits Formation, Utah; and Fruitland and Kirtland formations, New Mexico. The stratigraphic ranges of selected clades of dinosaur species are plotted on the chronostratigraphic framework, with some clades comprising short-duration species that do not overlap stratigraphically with preceding or succeeding forms. This is the expected pattern that is produced by an anagenetic mode of evolution, suggesting that true branching (speciation) events were rare and may have geographic significance. The recent hypothesis of intracontinental latitudinal provinciality of dinosaurs is shown to be affected by previous stratigraphic miscorrelation. Rapid stepwise acquisition of display characters in many dinosaur clades, in particular chasmosaurine ceratopsids, suggests that they may be useful for high resolution biostratigraphy.

  5. Automated Recognition of RNA Structure Motifs by Their SHAPE Data Signatures.

    PubMed

    Radecki, Pierce; Ledda, Mirko; Aviran, Sharon

    2018-06-14

    High-throughput structure profiling (SP) experiments that provide information at nucleotide resolution are revolutionizing our ability to study RNA structures. Of particular interest are RNA elements whose underlying structures are necessary for their biological functions. We previously introduced patteRNA , an algorithm for rapidly mining SP data for patterns characteristic of such motifs. This work provided a proof-of-concept for the detection of motifs and the capability of distinguishing structures displaying pronounced conformational changes. Here, we describe several improvements and automation routines to patteRNA . We then consider more elaborate biological situations starting with the comparison or integration of results from searches for distinct motifs and across datasets. To facilitate such analyses, we characterize patteRNA ’s outputs and describe a normalization framework that regularizes results. We then demonstrate that our algorithm successfully discerns between highly similar structural variants of the human immunodeficiency virus type 1 (HIV-1) Rev response element (RRE) and readily identifies its exact location in whole-genome structure profiles of HIV-1. This work highlights the breadth of information that can be gleaned from SP data and broadens the utility of data-driven methods as tools for the detection of novel RNA elements.

  6. Time averaging and stratigraphic disorder of molluscan assemblages in the Holocene sediments in the NE Adriatic (Piran)

    NASA Astrophysics Data System (ADS)

    Tomasovych, Adam; Gallmetzer, Ivo; Haselmair, Alexandra; Kaufman, Darrell S.; Zuschin, Martin

    2016-04-01

    Stratigraphic changes in temporal resolution of fossil assemblages and the degree of their stratigraphic mixing in the Holocene deposits are of high importance in paleoecology, conservation paleobiology and paleoclimatology. However, few studies quantified downcore changes in time averaging and in stratigraphic disorder on the basis of dating of multiple shells occurring in individual stratigraphic layers. Here, we investigate downcore changes in frequency distribution of postmortem ages of the infaunal bivalve Gouldia minima in two, ~150 cm-thick piston cores (separated by more than 1 km) in the northern Adriatic Sea, close to the Slovenian city Piran at a depth of 24 m. We use radiocarbon-calibrated amino acid racemization to obtain postmortem ages of 564 shells, and quantify age-frequency distributions in 4-5 cm-thick stratigraphic intervals (with 20-30 specimens sampled per interval). Inter-quartile range for individual 4-5 cm-thick layers varies between 850 and 1,700 years, and range encompassing 95% of age data varies between 2,000 and 5,000 years in both cores. The uppermost sediments (20 cm) are age-homogenized and show that median age of shells is ~700-800 years. The interval between 20 and 90 cm shows a gradual increase in median age from ~2,000 to ~5,000 years, with maximum age ranging to ~8,000 years. However, the lowermost parts of both cores show a significant disorder, with median age of 3,100-3,300 years. This temporal disorder implies that many shells were displaced vertically by ~1 m. Absolute and proportional abundance of the bivalve Gouldia minima strongly increases towards the top of the both cores. We hypothesize that such increase in abundance, when coupled with depth-declining reworking, can explain stratigraphic disorder because numerically abundant young shells from the top of the core were more likely buried to larger sediment depths than less frequent shells at intermediate sediment depths.

  7. Automated determination of fibrillar structures by simultaneous model building and fiber diffraction refinement.

    PubMed

    Potrzebowski, Wojciech; André, Ingemar

    2015-07-01

    For highly oriented fibrillar molecules, three-dimensional structures can often be determined from X-ray fiber diffraction data. However, because of limited information content, structure determination and validation can be challenging. We demonstrate that automated structure determination of protein fibers can be achieved by guiding the building of macromolecular models with fiber diffraction data. We illustrate the power of our approach by determining the structures of six bacteriophage viruses de novo using fiber diffraction data alone and together with solid-state NMR data. Furthermore, we demonstrate the feasibility of molecular replacement from monomeric and fibrillar templates by solving the structure of a plant virus using homology modeling and protein-protein docking. The generated models explain the experimental data to the same degree as deposited reference structures but with improved structural quality. We also developed a cross-validation method for model selection. The results highlight the power of fiber diffraction data as structural constraints.

  8. Differential compaction influences on structure in West Cameron Block 225 field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finley, W.R.

    The concept to be illustrated here is the influence on structural configuration of differential compaction caused by lateral variations in stratigraphy, specifically, changes from sand to shale within the same stratigraphic interval, The example chosen to illustrate this concept is West Cameron Block 225 field. As seen in structural stratigraphic cross sections as well as net sand maps constructed in the example field, several channel sands are seen to strongly influence the structural configuration. The basic structure within the field as defined by well and seismic data consists of a gentle, southerly dipping, north south-oriented ridge, bounded by a down-to-the-eastmore » fault on the west flank and a down-to-the-south fault to the north. Gentle roll into these faults closes the north flank of the structure. The stratigraphic section consists of alternating sands and shales of Miocene and Pliocene age. Several of these sands map out as linear sand bodies interpreted to be channels. These channels, representing thickened sand bodies that grade laterally into predominantly shale facies, are oriented in a general east-west direction. The juxtaposition of the basic structural orientation with the orientation of the channel sand(s) sets up a crossing point(s) on the southern flank of the structure. With the advent of differential compaction between the channel sands and the bounding shale faces, a stratigraphic structure is generated. This resulting compaction structure maps out as a double-lobed or saddled high. This effect is amplified as channels in the shallower section stack out over the southern flank of the structure until the southern crest dominates over the northern one. The overall result is one of migrating structural crests caused by variations in compactibility within the stratigraphic section.« less

  9. The stratigraphic distribution of large marine vertebrates and shell beds in the Pliocene of Tuscany

    NASA Astrophysics Data System (ADS)

    Dominici, Stefano; Benvenuti, Marco; Danise, Silvia

    2015-04-01

    The record of 337 shark fossils, 142 cetaceans and 10 sea cows from the Pliocene of Tuscany, mostly from historical museum collections, is revised. The majority of these fossils are concentrated at a few geographic sites from separated hinterland basins, on the South-Western side of the Northern Apennines. To better understand the meaning of these concentrations, the sequence stratigraphic distribution of more recent findings of large marine vertebrates is reconstructed against a high-resolution framework based on sedimentary facies analysis. These remains are usually covered by, or included in mudstones deposited far from the coast (N=12), skeletons being usually articulated, slightly displaced, and often bioeroded. A minor part of better preserved articulated skeletons is associated with sandstones from deltaic paleonenvironments (N=2). Marine mammal and shark remains may be associated with laterally-continuous shell accumulations, a type of concentration occurring at maximum flooding surfaces, separating relatively coarse-grained facies from open marine mudstones. Shell beds were bulk-sampled at 66 locations from six basins, covering a wide range of sedimentary facies, and spanning a chronologic interval of about 2.5 million years. A dataset of 62,655 mollusc specimens belonging to 496 species formed the basis of a statistical study to reconstruct the structure of the benthic communities, and to estimate paleodepths from intertidal to upper bathyal settings. Mollusc associations closely mirror the distribution of sedimentary facies, allowing for a fine tuning of the sequence stratigraphic architecture. Merging paleogeographic, stratigraphic and paleoecologic data, we conclude that the more abundant and diverse accumulations of large vertebrates took place in settings under the influence of coastal upwelling. A modern analogue occurs today in the Ligurian Sea, on the Tuscan offshore, where abundant nutrients carried by deep-marine currents of Western origin

  10. Venusian extended ejecta deposits as time-stratigraphic markers

    NASA Technical Reports Server (NTRS)

    Izenberg, Noam R.

    1992-01-01

    Use of impact crater ejects at time-stratigraphic markers was established during lunar geologic mapping efforts. The basic premise is that the deposition of impact ejecta, either by itself or mixed with impact-excavated material, is superimposed on a surface. The deposit becomes an observable, mappable unit produced in a single instant in geologic time. Up to two-thirds of Venus craters exhibit extended ejecta deposits. A reconnaissance survey of 336 craters (about 40 percent of the total population) was conducted. About half the craters examined were located in and around the Beta-Atla-Themis region, and half were spread over the western hemisphere of the planet. The survey was conducted using primarily C1-MIDR images. The preliminary survey shows: (1) of the 336 craters, 223 were found to have extended ejecta deposits. This proportion is higher than that found in other Venus crater databases by up to a factor of 2. (2) 53 percent of all extended ejecta craters were unambiguously superimposed on all volcanic and tectonic units. Crater Annia Faustina's associated parabolic ejecta deposit is clearly superimposed on volcanic flows coming from Gula Mons to the west. Parabola material from Faustina has covered the lava flows, smoothing the surface and reducing its specific backscatter cross section. The stratigraphy implies that the parabola material is the youngest observable unit in the region. (3) 12 percent of extended ejecta deposits are superimposed by volcanic materials. Crater Hwangcini has extended ejecta that has been covered by volcanic flows from a dome field to the northwest, implying that the volcanic units were emplaced subsequent to the ejecta deposit and are the youngest units in the locality. (4) It is difficult to determine the stratigraphic relationships of the remaining extended ejecta deposits in SAR at C1-MIDR resolution. Examination of higher resolution images and application of the other Magellan datasets in systematic manner should resolve

  11. Preliminary stratigraphic and hydrogeologic cross sections and seismic profile of the Floridan aquifer system of Broward County, Florida

    USGS Publications Warehouse

    Reese, Ronald S.; Cunningham, Kevin J.

    2013-01-01

    To help water-resource managers evaluate the Floridan aquifer system (FAS) as an alternative water supply, the U.S. Geological Survey initiated a study, in cooperation with the Broward County Environmental Protection and Growth Management Department, to refine the hydrogeologic framework of the FAS in the eastern part of Broward County. This report presents three preliminary cross sections illustrating stratigraphy and hydrogeology in eastern Broward County as well as an interpreted seismic profile along one of the cross sections. Marker horizons were identified using borehole geophysical data and were initially used to perform well-to-well correlation. Core sample data were integrated with the borehole geophysical data to support stratigraphic and hydrogeologic interpretations of marker horizons. Stratigraphic and hydrogeologic units were correlated across the county using borehole geophysical data from multiple wells. Seismic-reflection data were collected along the Hillsboro Canal. Borehole geophysical data were used to identify and correlate hydrogeologic units in the seismic-reflection profile. Faults and collapse structures that intersect hydrogeologic units were also identified in the seismic profile. The information provided in the cross sections and the seismic profile is preliminary and subject to revision.

  12. Geomorphologic, stratigraphic and sedimentologic evidences of tectonic activity in Sone-Ganga alluvial tract in Middle Ganga Plain, India

    NASA Astrophysics Data System (ADS)

    Sahu, Sudarsan; Saha, Dipankar

    2014-08-01

    The basement of the Ganga basin in the Himalayan foreland is criss-crossed by several faults, dividing the basin into several sub-blocks forming horsts, grabens, or half-grabens. Tectonic perturbations along basement faults have affected the fluvial regime and extent of sediment fill in different parts of the basin during Late Quaternary. The East Patna Fault (EPF) and the West Patna Fault (WPF), located in Sone-Ganga alluvial tract in the southern marginal parts of Middle Ganga Plain (MGP), have remained tectonically active. The EPF particularly has acted significantly and influenced in evolving the geomorphological landscape and the stratigraphic architecture of the area. The block bounded by the two faults has earlier been considered as a single entity, constituting a half-graben. The present investigation (by morpho-stratigraphic and sedimentologic means) has revealed the existence of yet another fault within the half-graben, referred to as Bishunpur-Khagaul Fault (BKF). Many of the long profile morphological characters (e.g., knick-zone, low width-depth ratio) of the Sone River at its lower reaches can be ascribed to local structural deformation along BKF. These basement faults in MGP lie parallel to each other in NE-SW direction.

  13. [Design of Complex Cavity Structure in Air Route System of Automated Peritoneal Dialysis Machine].

    PubMed

    Quan, Xiaoliang

    2017-07-30

    This paper introduced problems about Automated Peritoneal Dialysis machine(APD) that the lack of technical issues such as the structural design of the complex cavities. To study the flow characteristics of this special structure, the application of ANSYS CFX software is used with k-ε turbulence model as the theoretical basis of fluid mechanics. The numerical simulation of flow field simulation result in the internal model can be gotten after the complex structure model is imported into ANSYS CFX module. Then, it will present the distribution of complex cavities inside the flow field and the flow characteristics parameter, which will provide an important reference design for APD design.

  14. The study of features of the structural organization of the au-tomated information processing system of the collective type

    NASA Astrophysics Data System (ADS)

    Nikolaev, V. N.; Titov, D. V.; Syryamkin, V. I.

    2018-05-01

    The comparative assessment of the level of channel capacity of different variants of the structural organization of the automated information processing systems is made. The information processing time assessment model depending on the type of standard elements and their structural organization is developed.

  15. Auto-rickshaw: an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment.

    PubMed

    Panjikar, Santosh; Parthasarathy, Venkataraman; Lamzin, Victor S; Weiss, Manfred S; Tucker, Paul A

    2005-04-01

    The EMBL-Hamburg Automated Crystal Structure Determination Platform is a system that combines a number of existing macromolecular crystallographic computer programs and several decision-makers into a software pipeline for automated and efficient crystal structure determination. The pipeline can be invoked as soon as X-ray data from derivatized protein crystals have been collected and processed. It is controlled by a web-based graphical user interface for data and parameter input, and for monitoring the progress of structure determination. A large number of possible structure-solution paths are encoded in the system and the optimal path is selected by the decision-makers as the structure solution evolves. The processes have been optimized for speed so that the pipeline can be used effectively for validating the X-ray experiment at a synchrotron beamline.

  16. pmx: Automated protein structure and topology generation for alchemical perturbations

    PubMed Central

    Gapsys, Vytautas; Michielssens, Servaas; Seeliger, Daniel; de Groot, Bert L

    2015-01-01

    Computational protein design requires methods to accurately estimate free energy changes in protein stability or binding upon an amino acid mutation. From the different approaches available, molecular dynamics-based alchemical free energy calculations are unique in their accuracy and solid theoretical basis. The challenge in using these methods lies in the need to generate hybrid structures and topologies representing two physical states of a system. A custom made hybrid topology may prove useful for a particular mutation of interest, however, a high throughput mutation analysis calls for a more general approach. In this work, we present an automated procedure to generate hybrid structures and topologies for the amino acid mutations in all commonly used force fields. The described software is compatible with the Gromacs simulation package. The mutation libraries are readily supported for five force fields, namely Amber99SB, Amber99SB*-ILDN, OPLS-AA/L, Charmm22*, and Charmm36. PMID:25487359

  17. Instrumentation Automation for Concrete Structures: Report 2, Automation Hardware and Retrofitting Techniques, and Report 3, Available Data Collection and Reduction Software

    DTIC Science & Technology

    1987-06-01

    commercial products. · OP -- Typical cutout at a plumbiinc location where an automated monitoring system has bv :• installed. The sensor used with the...This report provides a description of commercially available sensors , instruments, and ADP equipment that may be selected to fully automate...automated. The automated plumbline monitoring system includes up to twelve sensors , repeaters, a system controller, and a printer. The system may

  18. Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta.

    PubMed

    Wang, Ray Yu-Ruei; Song, Yifan; Barad, Benjamin A; Cheng, Yifan; Fraser, James S; DiMaio, Frank

    2016-09-26

    Cryo-EM has revealed the structures of many challenging yet exciting macromolecular assemblies at near-atomic resolution (3-4.5Å), providing biological phenomena with molecular descriptions. However, at these resolutions, accurately positioning individual atoms remains challenging and error-prone. Manually refining thousands of amino acids - typical in a macromolecular assembly - is tedious and time-consuming. We present an automated method that can improve the atomic details in models that are manually built in near-atomic-resolution cryo-EM maps. Applying the method to three systems recently solved by cryo-EM, we are able to improve model geometry while maintaining the fit-to-density. Backbone placement errors are automatically detected and corrected, and the refinement shows a large radius of convergence. The results demonstrate that the method is amenable to structures with symmetry, of very large size, and containing RNA as well as covalently bound ligands. The method should streamline the cryo-EM structure determination process, providing accurate and unbiased atomic structure interpretation of such maps.

  19. PONDEROSA-C/S: client-server based software package for automated protein 3D structure determination.

    PubMed

    Lee, Woonghee; Stark, Jaime L; Markley, John L

    2014-11-01

    Peak-picking Of Noe Data Enabled by Restriction Of Shift Assignments-Client Server (PONDEROSA-C/S) builds on the original PONDEROSA software (Lee et al. in Bioinformatics 27:1727-1728. doi: 10.1093/bioinformatics/btr200, 2011) and includes improved features for structure calculation and refinement. PONDEROSA-C/S consists of three programs: Ponderosa Server, Ponderosa Client, and Ponderosa Analyzer. PONDEROSA-C/S takes as input the protein sequence, a list of assigned chemical shifts, and nuclear Overhauser data sets ((13)C- and/or (15)N-NOESY). The output is a set of assigned NOEs and 3D structural models for the protein. Ponderosa Analyzer supports the visualization, validation, and refinement of the results from Ponderosa Server. These tools enable semi-automated NMR-based structure determination of proteins in a rapid and robust fashion. We present examples showing the use of PONDEROSA-C/S in solving structures of four proteins: two that enable comparison with the original PONDEROSA package, and two from the Critical Assessment of automated Structure Determination by NMR (Rosato et al. in Nat Methods 6:625-626. doi: 10.1038/nmeth0909-625 , 2009) competition. The software package can be downloaded freely in binary format from http://pine.nmrfam.wisc.edu/download_packages.html. Registered users of the National Magnetic Resonance Facility at Madison can submit jobs to the PONDEROSA-C/S server at http://ponderosa.nmrfam.wisc.edu, where instructions, tutorials, and instructions can be found. Structures are normally returned within 1-2 days.

  20. AutoQSAR: an automated machine learning tool for best-practice quantitative structure-activity relationship modeling.

    PubMed

    Dixon, Steven L; Duan, Jianxin; Smith, Ethan; Von Bargen, Christopher D; Sherman, Woody; Repasky, Matthew P

    2016-10-01

    We introduce AutoQSAR, an automated machine-learning application to build, validate and deploy quantitative structure-activity relationship (QSAR) models. The process of descriptor generation, feature selection and the creation of a large number of QSAR models has been automated into a single workflow within AutoQSAR. The models are built using a variety of machine-learning methods, and each model is scored using a novel approach. Effectiveness of the method is demonstrated through comparison with literature QSAR models using identical datasets for six end points: protein-ligand binding affinity, solubility, blood-brain barrier permeability, carcinogenicity, mutagenicity and bioaccumulation in fish. AutoQSAR demonstrates similar or better predictive performance as compared with published results for four of the six endpoints while requiring minimal human time and expertise.

  1. Stratigraphic implications of trace element and strontium-isotope analyses of Kimmeridgian shell calcite from the Lower Saxony Basin, Germany

    NASA Astrophysics Data System (ADS)

    Zuo, Fanfan; Heimhofer, Ulrich; Huck, Stefan; Erbacher, Jochen; Bodin, Stephane

    2017-04-01

    Stratigraphic uncertainties due to the lack of open marine marker fossils (e.g. ammonites) hamper the precise age assignment and stratigraphic correlation of Kimmeridgian strata found in the Lower Saxony Basin of Northern Germany. Correlation of these deposits with the Jurassic standard ammonite zonation is still difficult, since the existing ostracod biostratigraphy is facies-controlled and of only limited stratigraphic precision. In this study, a chemostratigraphic approach has been chosen and biogenic shell material produced by brachiopods, oysters and lithiotids is evaluated for its reliability to act as proxy of the original Jurassic seawater strontium isotope composition. Low-Mg calcite shells have been collected from three stratigraphic sections accessible in open-cast quarries located in the Lower Saxony Basin of Northern Germany. In order to identify diagenetically altered shell calcite, trace element and stable isotope analysis of 227 calcite samples (oysters=101; brachiopods=60; Trichites=52) has been carried out. The geochemical results reveal that (1) concentration of different trace elements varies between the different groups of shell-forming organisms, which may be related to vital effects and (2) high strontium contents, low Mn and Fe contents and the lack of correlation between these elements indicate near-pristine calcite shells, and therefore shells are supposed to record the ambient sea water composition during the Late Jurassic. Strontium-isotope (87Sr/86Sr) analysis of diagenetically screened samples indicates an Early Kimmeridgian age of the studied deposits, which is in accordance with ostracod biostratigraphic data. An increasing trend in 87Sr/86Sr with stratigraphic height fits well with the global strontium-isotope curve. Besides, similar 87Sr/86Sr ratios derived from different organisms from a single stratigraphic level highlight the suitability of the shells for strontium-isotope stratigraphy. Despite the shallow-marine character of

  2. Lithofacies and sequence stratigraphic analysis of the Upper Jurassic siliciclastics in the eastern Kopet-Dagh Basin, NE Iran

    NASA Astrophysics Data System (ADS)

    Zand-Moghadam, Hamed; Moussavi-Harami, Reza; Mahboubi, Asadollah; Aghaei, Ali

    2016-05-01

    The Upper Jurassic (Oxfordian-Kimmeridgian) Mozduran Formation is the most important gas reservoirs of the northeast Iran. Siliciclastic facies of this formation in eastern most parts of the basin have not been studied yet. Therefore, four stratigraphic sections of Mozduran Formation have been selected in the Kole-Malekabad, Kale-Karab, Deraz-Ab and Karizak to interpret depositional history and analyze depositional sequences. Based on texture and sedimentary structures, 14 slilciclastic lithofacies were identified and classified into four categories, including conglomerate (Gms, Gp, Gt), sandstone (Sh, Sp, St, Sr, Sl, Sm, Se), mud rock (Fl) and intermediate sandstone-mud rock (Sr (Fl), Sr/Fl, Fl (Sr)). Identified lithofacies formed four architectural elements CH, SB, LA and FF. Lithofacies characteristics and architectural elements with mostly bimodal pattern of paleocurrents show that the majority of Mozduran lithofacies deposited in the coastal environment (tidal influence). Sequence stratigraphic analysis shows that the Kole-Malekabad section consists of two depositional sequences while other sections are characterized by three depositional sequences. The lower and upper sequence boundaries of the Mozduran Formation in all stratigraphic sections are SB1 that are distinguished by paleosol and sometime conglomerate horizons. Most of depositional sequences in studied sections are composed only of TST and HST. The TST deposits consist mostly of quartzarenite and litharenite petrofacies that have been deposited in the tidal zone. HST packages are mostly including mud rocks with interdeds of sandstone lithofacies that are deposited in supratidal setting. The LST facies is recognized only in the DS3 (equivalent to the second depositional sequences of the Kole-Malekabad), which consist of conglomerate facies. Instead, the Kole-Malekabad section is often composed of supratidal gypsiferrous shales, indicating sea level fall in the study area.

  3. PDB_REDO: automated re-refinement of X-ray structure models in the PDB.

    PubMed

    Joosten, Robbie P; Salzemann, Jean; Bloch, Vincent; Stockinger, Heinz; Berglund, Ann-Charlott; Blanchet, Christophe; Bongcam-Rudloff, Erik; Combet, Christophe; Da Costa, Ana L; Deleage, Gilbert; Diarena, Matteo; Fabbretti, Roberto; Fettahi, Géraldine; Flegel, Volker; Gisel, Andreas; Kasam, Vinod; Kervinen, Timo; Korpelainen, Eija; Mattila, Kimmo; Pagni, Marco; Reichstadt, Matthieu; Breton, Vincent; Tickle, Ian J; Vriend, Gert

    2009-06-01

    Structural biology, homology modelling and rational drug design require accurate three-dimensional macromolecular coordinates. However, the coordinates in the Protein Data Bank (PDB) have not all been obtained using the latest experimental and computational methods. In this study a method is presented for automated re-refinement of existing structure models in the PDB. A large-scale benchmark with 16 807 PDB entries showed that they can be improved in terms of fit to the deposited experimental X-ray data as well as in terms of geometric quality. The re-refinement protocol uses TLS models to describe concerted atom movement. The resulting structure models are made available through the PDB_REDO databank (http://www.cmbi.ru.nl/pdb_redo/). Grid computing techniques were used to overcome the computational requirements of this endeavour.

  4. First high-resolution stratigraphic column of the Martian north polar layered deposits

    USGS Publications Warehouse

    Fishbaugh, K.E.; Hvidberg, C.S.; Byrne, S.; Russell, P.S.; Herkenhoff, K. E.; Winstrup, M.; Kirk, R.

    2010-01-01

    This study achieves the first high-spatial-resolution, layer-scale, measured stratigraphic column of the Martian north polar layered deposits using a 1m-posting DEM. The marker beds found throughout the upper North Polar Layered Deposits range in thickness from 1.6 m-16.0 m +/-1.4 m, and 6 of 13 marker beds are separated by ???25-35 m. Thin-layer sets have average layer separations of 1.6 m. These layer separations may account for the spectral-power-peaks found in previous brightness-profile analyses. Marker-bed layer thicknesses show a weak trend of decreasing thickness with depth that we interpret to potentially be the result of a decreased accumulation rate in the past, for those layers. However, the stratigraphic column reveals that a simple rhythmic or bundled layer sequence is not immediately apparent throughout the column, implying that the relationship between polar layer formation and cyclic climate forcing is quite complex. Copyright ?? 2010 by the American Geophysical Union.

  5. First high-resolution stratigraphic column of the Martian north polar layered deposits

    NASA Astrophysics Data System (ADS)

    Fishbaugh, Kathryn E.; Hvidberg, Christine S.; Byrne, Shane; Russell, Patrick S.; Herkenhoff, Kenneth E.; Winstrup, Mai; Kirk, Randolph

    2010-04-01

    This study achieves the first high-spatial-resolution, layer-scale, measured stratigraphic column of the Martian north polar layered deposits using a 1m-posting DEM. The marker beds found throughout the upper North Polar Layered Deposits range in thickness from 1.6 m-16.0 m +/- 1.4 m, and 6 of 13 marker beds are separated by ˜25-35 m. Thin-layer sets have average layer separations of 1.6 m. These layer separations may account for the spectral-power-peaks found in previous brightness-profile analyses. Marker-bed layer thicknesses show a weak trend of decreasing thickness with depth that we interpret to potentially be the result of a decreased accumulation rate in the past, for those layers. However, the stratigraphic column reveals that a simple rhythmic or bundled layer sequence is not immediately apparent throughout the column, implying that the relationship between polar layer formation and cyclic climate forcing is quite complex.

  6. Stratigraphy of Aeolis Dorsa, Mars: Stratigraphic context of the great river deposits

    NASA Astrophysics Data System (ADS)

    Kite, Edwin S.; Howard, Alan D.; Lucas, Antoine S.; Armstrong, John C.; Aharonson, Oded; Lamb, Michael P.

    2015-06-01

    Unraveling the stratigraphic record is the key to understanding ancient climate and past climate changes on Mars (Grotzinger, J. et al. [2011]. Astrobiology 11, 77-87). Stratigraphic records of river deposits hold particular promise because rain or snowmelt must exceed infiltration plus evaporation to allow sediment transport by rivers. Therefore, river deposits when placed in stratigraphic order could constrain the number, magnitudes, and durations of the wettest (and presumably most habitable) climates in Mars history. We use crosscutting relationships to establish the stratigraphic context of river and alluvial-fan deposits in the Aeolis Dorsa sedimentary basin, 10°E of Gale crater. At Aeolis Dorsa, wind erosion has exhumed a stratigraphic section of sedimentary rocks consisting of at least four unconformity-bounded rock packages, recording three or more distinct episodes of surface runoff. Early deposits (>700 m thick) are embayed by river deposits (>400 m thick), which are in turn unconformably draped by fan-shaped deposits (<100 m thick) which we interpret as alluvial fans. Yardang-forming layered deposits (>900 m thick) unconformably drape all previous deposits. River deposits embay a dissected landscape formed of sedimentary rock. The river deposits are eroding out of at least two distinguishable units. There is evidence for pulses of erosion during the interval of river deposition. The total interval spanned by river deposits is >(1 × 106-2 × 107) yr, and this is extended if we include alluvial-fan deposits. Alluvial-fan deposits unconformably postdate thrust faults which crosscut the river deposits. This relationship suggests a relatively dry interval of >4 × 107 yr after the river deposits formed and before the fan-shaped deposits formed, based on probability arguments. Yardang-forming layered deposits unconformably postdate all of the earlier deposits. They contain rhythmite and their induration suggests a damp or wet (near-) surface environment

  7. Amazon Forest Structure from IKONOS Satellite Data and the Automated Characterization of Forest Canopy Properties

    Treesearch

    Michael Palace; Michael Keller; Gregory P. Asner; Stephen Hagen; Bobby Braswell

    2008-01-01

    We developed an automated tree crown analysis algorithm using 1-m panchromatic IKONOS satellite images to examine forest canopy structure in the Brazilian Amazon. The algorithm was calibrated on the landscape level with tree geometry and forest stand data at the Fazenda Cauaxi (3.75◦ S, 48.37◦ W) in the eastern Amazon, and then compared with forest...

  8. Automated Fabrication Technologies for High Performance Polymer Composites

    NASA Technical Reports Server (NTRS)

    Shuart , M. J.; Johnston, N. J.; Dexter, H. B.; Marchello, J. M.; Grenoble, R. W.

    1998-01-01

    New fabrication technologies are being exploited for building high graphite-fiber-reinforced composite structure. Stitched fiber preforms and resin film infusion have been successfully demonstrated for large, composite wing structures. Other automatic processes being developed include automated placement of tacky, drapable epoxy towpreg, automated heated head placement of consolidated ribbon/tape, and vacuum-assisted resin transfer molding. These methods have the potential to yield low cost high performance structures by fabricating composite structures to net shape out-of-autoclave.

  9. Automated generation of weld path trajectories.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sizemore, John M.; Hinman-Sweeney, Elaine Marie; Ames, Arlo Leroy

    2003-06-01

    AUTOmated GENeration of Control Programs for Robotic Welding of Ship Structure (AUTOGEN) is software that automates the planning and compiling of control programs for robotic welding of ship structure. The software works by evaluating computer representations of the ship design and the manufacturing plan. Based on this evaluation, AUTOGEN internally identifies and appropriately characterizes each weld. Then it constructs the robot motions necessary to accomplish the welds and determines for each the correct assignment of process control values. AUTOGEN generates these robot control programs completely without manual intervention or edits except to correct wrong or missing input data. Most shipmore » structure assemblies are unique or at best manufactured only a few times. Accordingly, the high cost inherent in all previous methods of preparing complex control programs has made robot welding of ship structures economically unattractive to the U.S. shipbuilding industry. AUTOGEN eliminates the cost of creating robot control programs. With programming costs eliminated, capitalization of robots to weld ship structures becomes economically viable. Robot welding of ship structures will result in reduced ship costs, uniform product quality, and enhanced worker safety. Sandia National Laboratories and Northrop Grumman Ship Systems worked with the National Shipbuilding Research Program to develop a means of automated path and process generation for robotic welding. This effort resulted in the AUTOGEN program, which has successfully demonstrated automated path generation and robot control. Although the current implementation of AUTOGEN is optimized for welding applications, the path and process planning capability has applicability to a number of industrial applications, including painting, riveting, and adhesive delivery.« less

  10. Approaches to automated protein crystal harvesting

    PubMed Central

    Deller, Marc C.; Rupp, Bernhard

    2014-01-01

    The harvesting of protein crystals is almost always a necessary step in the determination of a protein structure using X-ray crystallographic techniques. However, protein crystals are usually fragile and susceptible to damage during the harvesting process. For this reason, protein crystal harvesting is the single step that remains entirely dependent on skilled human intervention. Automation has been implemented in the majority of other stages of the structure-determination pipeline, including cloning, expression, purification, crystallization and data collection. The gap in automation between crystallization and data collection results in a bottleneck in throughput and presents unfortunate opportunities for crystal damage. Several automated protein crystal harvesting systems have been developed, including systems utilizing microcapillaries, microtools, microgrippers, acoustic droplet ejection and optical traps. However, these systems have yet to be commonly deployed in the majority of crystallography laboratories owing to a variety of technical and cost-related issues. Automation of protein crystal harvesting remains essential for harnessing the full benefits of fourth-generation synchrotrons, free-electron lasers and microfocus beamlines. Furthermore, automation of protein crystal harvesting offers several benefits when compared with traditional manual approaches, including the ability to harvest microcrystals, improved flash-cooling procedures and increased throughput. PMID:24637746

  11. Automated Quality Assessment of Structural Magnetic Resonance Brain Images Based on a Supervised Machine Learning Algorithm.

    PubMed

    Pizarro, Ricardo A; Cheng, Xi; Barnett, Alan; Lemaitre, Herve; Verchinski, Beth A; Goldman, Aaron L; Xiao, Ena; Luo, Qian; Berman, Karen F; Callicott, Joseph H; Weinberger, Daniel R; Mattay, Venkata S

    2016-01-01

    High-resolution three-dimensional magnetic resonance imaging (3D-MRI) is being increasingly used to delineate morphological changes underlying neuropsychiatric disorders. Unfortunately, artifacts frequently compromise the utility of 3D-MRI yielding irreproducible results, from both type I and type II errors. It is therefore critical to screen 3D-MRIs for artifacts before use. Currently, quality assessment involves slice-wise visual inspection of 3D-MRI volumes, a procedure that is both subjective and time consuming. Automating the quality rating of 3D-MRI could improve the efficiency and reproducibility of the procedure. The present study is one of the first efforts to apply a support vector machine (SVM) algorithm in the quality assessment of structural brain images, using global and region of interest (ROI) automated image quality features developed in-house. SVM is a supervised machine-learning algorithm that can predict the category of test datasets based on the knowledge acquired from a learning dataset. The performance (accuracy) of the automated SVM approach was assessed, by comparing the SVM-predicted quality labels to investigator-determined quality labels. The accuracy for classifying 1457 3D-MRI volumes from our database using the SVM approach is around 80%. These results are promising and illustrate the possibility of using SVM as an automated quality assessment tool for 3D-MRI.

  12. Automated fine structure image analysis method for discrimination of diabetic retinopathy stage using conjunctival microvasculature images

    PubMed Central

    Khansari, Maziyar M; O’Neill, William; Penn, Richard; Chau, Felix; Blair, Norman P; Shahidi, Mahnaz

    2016-01-01

    The conjunctiva is a densely vascularized mucus membrane covering the sclera of the eye with a unique advantage of accessibility for direct visualization and non-invasive imaging. The purpose of this study is to apply an automated quantitative method for discrimination of different stages of diabetic retinopathy (DR) using conjunctival microvasculature images. Fine structural analysis of conjunctival microvasculature images was performed by ordinary least square regression and Fisher linear discriminant analysis. Conjunctival images between groups of non-diabetic and diabetic subjects at different stages of DR were discriminated. The automated method’s discriminate rates were higher than those determined by human observers. The method allowed sensitive and rapid discrimination by assessment of conjunctival microvasculature images and can be potentially useful for DR screening and monitoring. PMID:27446692

  13. Stratigraphic framework and evolution of the Cretaceous continental sequences of the Bauru, Sanfranciscana, and Parecis basins, Brazil

    NASA Astrophysics Data System (ADS)

    Batezelli, Alessandro; Ladeira, Francisco Sergio Bernardes

    2016-01-01

    With the breakup of the supercontinent Gondwana, the South American Plate has undergone an intense process of tectonic restructuring that led to the genesis of the interior basins that encompassed continental sedimentary sequences. The Brazilian Bauru, Sanfranciscana and Parecis basins during Late Cretaceous have had their evolution linked to this process of structuring and therefore have very similar sedimentary characteristics. The purpose of this study is to establish a detailed understanding of alluvial sedimentary processes and architecture within a stratigraphic sequence framework using the concept of the stratigraphic base level or the ratio between the accommodation space and sediment supply. The integration of the stratigraphic and facies data contributed to defining the stratigraphic architecture of the Bauru, Sanfranciscana and Parecis Basins, supporting a model for continental sequences that depicts qualitative changes in the sedimentation rate (S) and accommodation space (A) that occurred during the Cretaceous. This study discusses the origin of the unconformity surfaces (K-0, K-1 and K-1A) that separate Sequences 1, 2A and 2B and the sedimentary characteristics of the Bauru, Sanfranciscana and Parecis Basins from the Aptian to the Maastrichtian, comparing the results with other Cretaceous Brazilian basins. The lower Cretaceous Sequence 1 (Caiuá and Areado groups) is interpreted as a low-accommodation systems tract compound by fluvial and aeolian systems. The upper Cretaceous lacustrine, braided river-dominated alluvial fan and aeolian systems display characteristics of the evolution from high-to low-accommodation systems tracts (Sequences 2A and 2B). Unconformity K-0 is related to the origin of the Bauru Basin itself in the Early Cretaceous. In Sanfranciscana and Parecis basins, the unconformity K-0 marks the contact between aeolian deposits from Lower Cretaceous and Upper Cretaceous alluvial systems (Sequences 1 and 2). Unconformity K-1, which was

  14. Stratigraphic architecture and gamma ray logs of deeper ramp carbonates (Upper Jurassic, SW Germany)

    NASA Astrophysics Data System (ADS)

    Pawellek, T.; Aigner, T.

    2003-07-01

    The objective of this paper is to contribute to the development of sequence stratigraphic models for extensive epicontinental carbonate systems deposited over cratonic areas. Epicontinental carbonates of the SW German Upper Jurassic were analysed in terms of microfacies, sedimentology and sequence stratigraphy based on 2.5 km of core, 70 borehole gamma ray logs and 24 quarries. Facies analysis revealed six major facies belts across the deeper parts of the carbonate ramp, situated generally below fair-weather wave base, and mostly below average storm wave base but in the reach of occasional storm events. Observed stratigraphic patterns differ in some aspects from widely published sequence stratigraphic models: Elementary sedimentary cycles are mostly more or less symmetrical and are, thus, referred to as "genetic sequences" or "genetic units" [AAAPG Bull. 55 (1971) 1137; Frazier, D.E., 1974. Depositional episodes: their relationship to the Quaternary stratigraphic framework in the northwestern portion of the Gulf Basin. University of Texas, Austin, Bureau of Economic Geology Geologicalo Circular 71-1; AAPG Bull. 73 (1989) 125; Galloway, W.E., Hobday, D.K., 1996. Terrigenous Clastic Depositional Systems. 489 pp., Springer; Cross, T.A., Baker, M.R., Chapin, M.S., Clark, M.S., Gardner, M.H., Hanson, M.S., Lessenger, M.A., Little, L.D., McDonough, K.J., Sonnenfeld, M.D., Valasek, D.W., Williams, M.R., Witter, D.N., 1993. Applications of high-resolution sequence stratigraphy to reservoir analysis. Edition Technip 1993, 11-33; Bull. Cent. Rech. Explor. Prod. Elf-Aquitaine 16 (1992) 357; Homewood, P., Mauriaud, P., Lafont, F., 2000. Best practices in sequence stratigraphy. Elf EP Mem. 25, 81 pp.; Homewood, P., Eberli, G.P., 2000. Genetic stratigraphy on the exploration and production scales. Elf EP Mem. 24, 290 pp.], in contrast to the asymmetrical, shallowing-upward "parasequences" of the EXXON approach. Neither sequence boundaries nor maximum flooding surfaces could be

  15. Controlling factors of stratigraphic occurrences of fine-grained turbidites: Examples from the Japanese waters

    NASA Astrophysics Data System (ADS)

    Ikehara, K.

    2017-12-01

    Fine-grained turbidite has been used for subaqueous paleoseismology, and has been recognized from shallow- to deep-water environments around the Japanese islands. Stratigraphic occurrence of fine-grained turbidites in the deepest Beppu Bay, south Japan, with its water depth of 75 m suggest clear influence of sea-level changes. Turbidite frequency was high during the post glacial sea-level rising and last 2.7 ka, and was low during the Holocene maximum sea-level highstand (5.3-2.7 ka). Retreat and progress of coastal delta front of the nearby river might affect the sediment supply to the deepest basin. On the other hand, fine-grained turbidites found in the forearc basins ( 3500 and 4500 m in water depths) and trench floor ( 6000 m in water depth) along the southern Ryukyu arc have no clear relation with sea-level changes. Sediment and bathymetric characteristics suggest that origin of these fine-grained turbidites is Taiwan. Remarkable tectonic uplift of Taiwanese coast with small mountainous rivers and narrow shelf may produce the continuous supply of fine-grained turbidites in this area. The Japan Trench floor composes of a series of small basins reflecting subducting horst-graben structure of the Pacific Plate. Each small basin acts as a natural sediment trap receiving the earthquake-induced turbidity currents. Thick fine-grained turbidites are also occurred in the small basins in the Japan Trench floor ( 7500 m in water depth). These are most likely induced by huge earthquakes along the Japan Trench. Thus, their stratigraphic occurrences might have close relation with recurrence of huge earthquakes in the past.

  16. Automation or De-automation

    NASA Astrophysics Data System (ADS)

    Gorlach, Igor; Wessel, Oliver

    2008-09-01

    In the global automotive industry, for decades, vehicle manufacturers have continually increased the level of automation of production systems in order to be competitive. However, there is a new trend to decrease the level of automation, especially in final car assembly, for reasons of economy and flexibility. In this research, the final car assembly lines at three production sites of Volkswagen are analysed in order to determine the best level of automation for each, in terms of manufacturing costs, productivity, quality and flexibility. The case study is based on the methodology proposed by the Fraunhofer Institute. The results of the analysis indicate that fully automated assembly systems are not necessarily the best option in terms of cost, productivity and quality combined, which is attributed to high complexity of final car assembly systems; some de-automation is therefore recommended. On the other hand, the analysis shows that low automation can result in poor product quality due to reasons related to plant location, such as inadequate workers' skills, motivation, etc. Hence, the automation strategy should be formulated on the basis of analysis of all relevant aspects of the manufacturing process, such as costs, quality, productivity and flexibility in relation to the local context. A more balanced combination of automated and manual assembly operations provides better utilisation of equipment, reduces production costs and improves throughput.

  17. Structural and stratigraphic framework and spatial distribution of permeability of the Atlantic coastal plain, North Carolina to New York

    USGS Publications Warehouse

    Brown, Philip Monroe; Miller, James A.; Swain, Frederick Morrill

    1972-01-01

    This report describes and interprets the results of a detailed subsurface mapping program undertaken in that part of the Atlantic Coastal Plain which extends from the South Carolina and North Carolina border through Long Island, N.Y. Data obtained from more than 2,200 wells are analyzed. Seventeen chronostratigraphic units are mapped in the subsurface. They range in age from Jurassic(?) to post-Miocene. The purpose of the mapping program was to determine the external and internal geometry of mappable chronostratigraphic units and to derive and construct a permeability-distribution network for each unit based upon contrasts in the textures and compositions of its contained sediments. The report contains a structure map and a combined isopach, lithofacies, and permeability-distribution map for each of the chronostratigraphic units delineated in the subsurface. In addition, it contains a map of the top of the basement surface. These maps, together with 36 stratigraphic cross sections, present a three-dimensional view of the regional subsurface hydrogeology. They provide focal points of reference for a discussion of regional tectonics, structure, stratigraphy, and permeability distribution. Taken together and in chronologic sequence, the maps constitute a detailed sedimentary model, the first such model to be constructed for the middle Atlantic Coastal Plain. The chronostratigraphic units mapped record a structural history dominated by lateral and vertical movement along a system of intersecting hinge zones. Taphrogeny, related to transcurrent faulting, is the dominant type of deformation that controlled the geometry of the sedimentary model. Twelve of the seventeen chronostratigraphic units mapped have depositional alinements and thickening trends that are independent of the present-day configuration of the underlying basement surface. These 12 units, classified as genetically unrooted units, are assigned to a first-order tectonic stage. A structural model is proposed

  18. Strategies Toward Automation of Overset Structured Surface Grid Generation

    NASA Technical Reports Server (NTRS)

    Chan, William M.

    2017-01-01

    An outline of a strategy for automation of overset structured surface grid generation on complex geometries is described. The starting point of the process consists of an unstructured surface triangulation representation of the geometry derived from a native CAD, STEP, or IGES definition, and a set of discretized surface curves that captures all geometric features of interest. The procedure for surface grid generation is decomposed into an algebraic meshing step, a hyperbolic meshing step, and a gap-filling step. This paper will focus primarily on the high-level plan with details on the algebraic step. The algorithmic procedure for the algebraic step involves analyzing the topology of the network of surface curves, distributing grid points appropriately on these curves, identifying domains bounded by four curves that can be meshed algebraically, concatenating the resulting grids into fewer patches, and extending appropriate boundaries of the concatenated grids to provide proper overlap. Results are presented for grids created on various aerospace vehicle components.

  19. Stratigraphic and structural reconstruction of an Upper Ordovician super-eruption (Catalan Pyrenees)

    NASA Astrophysics Data System (ADS)

    Marti, Joan; Casas, Josep Maria; Muñoz, Josep A.

    2017-04-01

    Pre-Variscan basement of the Pyrenees includes evidence of many magmatic episodes represented by different types of granitoids and volcanic rocks, which indicates the complex geodynamic history of this peri-Gondwana terrane during Palaeozoic. One of the most significative magmatic episodes is that of Upper Ordovician (Caradocian) age, which is represented by several granitic and granodioritic bodies and volcanic rocks mostly of pyroclastic nature. In the Catalan Pyrenees this magmatism is well represented in the Ribes de Freser and Nuria area, where the orthogneisses from the Nuria massif and the Ribes granophyre, both with a similar age of 457 Ma, seem to form a calc-alkaline plutonic suite covering terms from deeper to shallower levels. The presence of numerous pyroclastic deposits and lavas interbedded with Caradocian sediments and intruded by and immediately above the Ribes granophyre, suggests that this intrusive episode also generated significant volcanism. The area also hosts an important volume of rhyolitic ignimbrites and andesitic lavas strongly affected by Alpine tectonics and commonly showing tectonised contacts at the base and top of the sequences. These volcanic rocks were previously attributed to the Upper Carboniferous late-Variscan volcanism, extensively represented in the Pyrenees. However, new laser ablation U-Pb zircon geochronology from these rocks has revealed an Upper Ordovician age ( 455 Ma), similar to that of the plutonic rocks of the same area, thus suggesting a probable genetic relation between all them. The palinspatic reconstruction of the Alpine and Variscan tectonic units that affect this area has permitted to infer the geometry, facies distribution, original position, and thickness of these volcanic rocks previously attributed to the late-Variscan volcanism, and reveals how they are spatially (and stratigraphically) associated with the previously identified Late Ordovician volcanic rocks. In particular, the volcanic rocks cropping

  20. Chemical Contaminants as Stratigraphic Markers for the Anthropocene

    NASA Astrophysics Data System (ADS)

    Kruge, M. A.

    2012-12-01

    Thousands and even millions of years from now, widespread anthropogenic contaminants in sediments would likely persist, incorporated into the geological record. They would inadvertently preserve evidence of our present era (informally designated as the Anthropocene Epoch) characterized by large human populations engaged in intensive industrial and agricultural activities. Hypothetical geologists in the distant future would likely find unusually high concentrations of a wide variety of contaminants at stratigraphic levels corresponding to our present time, analogous to the iridium anomaly marking the bolide impact event at the close of the Cretaceous Period. These would include both organic and inorganic substances, such as industrially-derived heavy metals (e.g., Hg, Pb, Cr, Zn) and hydrocarbons, both petrogenic (derived directly from petroleum) and pyrogenic (combustion products). While there are natural sources for these materials, such as volcanic eruptions, wildfires, and oil seeps, their co-occurrence would provide a signature characteristic of human activity. Diagnostic assemblages of organic compounds would carry an anthropogenic imprint. The distribution of polycyclic aromatic hydrocarbons (PAHs) in a sediment sample could distinguish between natural and human sources. Stable isotopic signatures would provide additional evidence. Concentrations of contaminants in the sedimentary record would increase exponentially with increasing proximity to urban source areas, where at present billions of people are collectively consuming vast quantities of fossil fuels and generating large amounts of waste. Aolian and marine transport prior to deposition has been seen at present to globally redistribute detectable amounts of contaminants including Hg and PAHs, even at great distances from principal source areas. For organic contaminants, deposition in an anoxic sedimentary environment could insure their preservation, increasing the likelihood of their inclusion in the

  1. Gas production from a cold, stratigraphically-bounded gas hydrate deposit at the Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope: Implications of uncertainties

    USGS Publications Warehouse

    Moridis, G.J.; Silpngarmlert, S.; Reagan, M.T.; Collett, T.; Zhang, K.

    2011-01-01

    As part of an effort to identify suitable targets for a planned long-term field test, we investigate by means of numerical simulation the gas production potential from unit D, a stratigraphically bounded (Class 3) permafrost-associated hydrate occurrence penetrated in the BPXA-DOE-USGS Mount Elbert Gas Hydrate Stratigraphic Test Well on North Slope, Alaska. This shallow, low-pressure deposit has high porosities (?? = 0.4), high intrinsic permeabilities (k = 10-12 m2) and high hydrate saturations (SH = 0.65). It has a low temperature (T = 2.3-2.6 ??C) because of its proximity to the overlying permafrost. The simulation results indicate that vertical wells operating at a constant bottomhole pressure would produce at very low rates for a very long period. Horizontal wells increase gas production by almost two orders of magnitude, but production remains low. Sensitivity analysis indicates that the initial deposit temperature is by the far the most important factor determining production performance (and the most effective criterion for target selection) because it controls the sensible heat available to fuel dissociation. Thus, a 1 ??C increase in temperature is sufficient to increase the production rate by a factor of almost 8. Production also increases with a decreasing hydrate saturation (because of a larger effective permeability for a given k), and is favored (to a lesser extent) by anisotropy. ?? 2010.

  2. Managing Automation: A Process, Not a Project.

    ERIC Educational Resources Information Center

    Hoffmann, Ellen

    1988-01-01

    Discussion of issues in management of library automation includes: (1) hardware, including systems growth and contracts; (2) software changes, vendor relations, local systems, and microcomputer software; (3) item and authority databases; (4) automation and library staff, organizational structure, and managing change; and (5) environmental issues,…

  3. Kotai Antibody Builder: automated high-resolution structural modeling of antibodies.

    PubMed

    Yamashita, Kazuo; Ikeda, Kazuyoshi; Amada, Karlou; Liang, Shide; Tsuchiya, Yuko; Nakamura, Haruki; Shirai, Hiroki; Standley, Daron M

    2014-11-15

    Kotai Antibody Builder is a Web service for tertiary structural modeling of antibody variable regions. It consists of three main steps: hybrid template selection by sequence alignment and canonical rules, 3D rendering of alignments and CDR-H3 loop modeling. For the last step, in addition to rule-based heuristics used to build the initial model, a refinement option is available that uses fragment assembly followed by knowledge-based scoring. Using targets from the Second Antibody Modeling Assessment, we demonstrate that Kotai Antibody Builder generates models with an overall accuracy equal to that of the best-performing semi-automated predictors using expert knowledge. Kotai Antibody Builder is available at http://kotaiab.org standley@ifrec.osaka-u.ac.jp. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  4. Stratigraphic, regional unconformity analysis and potential petroleum plays of East Siberian Sea Basin

    NASA Astrophysics Data System (ADS)

    Karpov, Yury; Stoupakova, Antonina; Suslova, Anna; Agasheva, Mariia

    2017-04-01

    The East Siberian Sea basin (ESSB) one of the most unexplored part of the Russian Arctic shelf, extending for over 1000 km from New Siberian Islands archipelago to Wrangel Island. This region is considered as a region with probable high petroleum potential. Within the ESSB several phases of orogeny are recognized [1]: Elsmerian orogeny in Early Devonian, Early Brooks orogeny in Early Cretaceous, Late Brooks orogeny in Late Cretaceous. Two generations of the basins could be outlined. Both of these generations are controlled by the basement domains [1]: Paleozoic (post-Devonian) to Mesozoic basins preserved north of the Late Mesozoic frontal thrusts; Aptian-Albian to Quaternary basins, postdating the Verkhoyansk-Brookian orogeny, and evolving mainly over the New-Siberian-Chukchi Fold Belt. Basin is filled with siliclastic sediments and in the deepest depocentres sediments thickness exceeds 8-10 km in average. Seismic data was interpreted using methods of seismic stratigraphy. Finally, main seismic horizons were indicated and each horizon follows regional stratigraphic unconformities: mBU - in base of Cenozoic, BU - in base of Upper Cretaceous, LCU - in base of Cretaceous, JU - in middle of Jurassic, F - in top of Basement. In ESSB, we can identify Permian, Triassic, Jurassic, Cretaceous, Paleogene and Neogene seismic stratigraphy complexes. Perspective structures, investigated in ESSB were founded out by comparing seismogeological cross-sections with explored analogs in other onshore and offshore basins [2, 3, 4]. The majority of structures could be connected with stratigraphic and fault traps. The most perspective prospects are probably connected with grabens and depressions, where thickness of sediments exceed 10 km. Reservoirs in ESSB are proposed by regional geological explorations on New Siberian Islands Archipelago and Wrangel Island. Potential seals are predominantly assigned to Jurassic and Cretaceous periods. Thick clinoform units of various geometry and

  5. Automated segmentation of neuroanatomical structures in multispectral MR microscopy of the mouse brain.

    PubMed

    Ali, Anjum A; Dale, Anders M; Badea, Alexandra; Johnson, G Allan

    2005-08-15

    We present the automated segmentation of magnetic resonance microscopy (MRM) images of the C57BL/6J mouse brain into 21 neuroanatomical structures, including the ventricular system, corpus callosum, hippocampus, caudate putamen, inferior colliculus, internal capsule, globus pallidus, and substantia nigra. The segmentation algorithm operates on multispectral, three-dimensional (3D) MR data acquired at 90-microm isotropic resolution. Probabilistic information used in the segmentation is extracted from training datasets of T2-weighted, proton density-weighted, and diffusion-weighted acquisitions. Spatial information is employed in the form of prior probabilities of occurrence of a structure at a location (location priors) and the pairwise probabilities between structures (contextual priors). Validation using standard morphometry indices shows good consistency between automatically segmented and manually traced data. Results achieved in the mouse brain are comparable with those achieved in human brain studies using similar techniques. The segmentation algorithm shows excellent potential for routine morphological phenotyping of mouse models.

  6. Stratigraphic cross section of measured sections and drill holes of the Neslan Formation and adjacent formations, Book Cliffs Area, Colorado and Utah

    USGS Publications Warehouse

    Kirshbaum, Mark A.; Spear, Brianne D.

    2012-01-01

    This study updates a stratigraphic cross section published as plate 2 in Kirschbaum and Hettinger (2004) Digital Data Series 69-G (http://pubs.usgs.gov/dds/dds-069/dds-069-g/). The datum is a marine/tidal ravinement surface within the Cozzette Sandstone Member of the Iles Formation and the Thompson Canyon Sandstone and Sulphur Canyon Sandstone Beds of the Neslen Formation. One of the cores shown was included on the original cross section, and new core descriptions have been added to the upper part of the cored interval. A new core description (S178) is included in this report. Cores are stored in the U.S. Geological Survey Core Research Facility at the Denver Federal Center, Colorado. The following information has also been added to help define the stratigraphic framework: 1) At least five claystones interpreted as altered volcanic ashes have been identified and may give future workers a correlation tool within the largely continental section. 2) Thickness and general geometry of the Sego Sandstone, Buck Tongue of the Mancos Shale, and Castlegate Sandstone have been added to provide additional stratigraphic context. 3) The geometry in the Sego Sandstone, Buck Tongue of the Mancos Shale, and Castlegate Sandstone has been added to provide additional stratigraphic context. 4) Ammonite collections are from Gill and Hail. The zone of Didymoceras nebrascense projected into the East Salt Wash area is based on correlation of the flooding surface at the base of the Cozzette Member to this point as shown in Kirschbaum and Hettinger. 5) A leaf locality of the Denver Museum of Nature and Science is shown in its approximate stratigraphic position near Thompson Canyon. 6) A dinosaur locality of the Natural History Museum of Utah is shown in the Horse Canyon area measured section at the stratigraphic position where it was extracted.

  7. Modelling and interpreting biologically crusted dryland soil sub-surface structure using automated micropenetrometry

    NASA Astrophysics Data System (ADS)

    Hoon, Stephen R.; Felde, Vincent J. M. N. L.; Drahorad, Sylvie L.; Felix-Henningsen, Peter

    2015-04-01

    Soil penetrometers are used routinely to determine the shear strength of soils and deformable sediments both at the surface and throughout a depth profile in disciplines as diverse as soil science, agriculture, geoengineering and alpine avalanche-safety (e.g. Grunwald et al. 2001, Van Herwijnen et al. 2009). Generically, penetrometers comprise two principal components: An advancing probe, and a transducer; the latter to measure the pressure or force required to cause the probe to penetrate or advance through the soil or sediment. The force transducer employed to determine the pressure can range, for example, from a simple mechanical spring gauge to an automatically data-logged electronic transducer. Automated computer control of the penetrometer step size and probe advance rate enables precise measurements to be made down to a resolution of 10's of microns, (e.g. the automated electronic micropenetrometer (EMP) described by Drahorad 2012). Here we discuss the determination, modelling and interpretation of biologically crusted dryland soil sub-surface structures using automated micropenetrometry. We outline a model enabling the interpretation of depth dependent penetration resistance (PR) profiles and their spatial differentials using the model equations, σ {}(z) ={}σ c0{}+Σ 1n[σ n{}(z){}+anz + bnz2] and dσ /dz = Σ 1n[dσ n(z) /dz{} {}+{}Frn(z)] where σ c0 and σ n are the plastic deformation stresses for the surface and nth soil structure (e.g. soil crust, layer, horizon or void) respectively, and Frn(z)dz is the frictional work done per unit volume by sliding the penetrometer rod an incremental distance, dz, through the nth layer. Both σ n(z) and Frn(z) are related to soil structure. They determine the form of σ {}(z){} measured by the EMP transducer. The model enables pores (regions of zero deformation stress) to be distinguished from changes in layer structure or probe friction. We have applied this method to both artificial calibration soils in the

  8. Ordovician and Silurian Phi Kappa and Trail Creek formations, Pioneer Mountains, central Idaho; stratigraphic and structural revisions, and new data on graptolite faunas

    USGS Publications Warehouse

    Dover, James H.; Berry, William B.N.; Ross, Reuben James

    1980-01-01

    Recent geologic mapping in the northern Pioneer Mountains combined with the identification of graptolites from 116 new collections indicate that the Ordovician and Silurian Phi Kappa and Trail Creek Formations occur in a series of thrust-bounded slices within a broad zone of imbricate thrust faulting. Though confirming a deformational style first reported in a 1963 study by Michael Churkin, our data suggest that the complexity and regional extent of the thrust zone were not previously recognized. Most previously published sections of the Phi Kappa and Trail Creek Formations were measured across unrecognized thrust faults and therefore include not only structural repetitions of graptolitic Ordovician and Silurian rocks but also other tectonically juxtaposed lithostratigraphic units of diverse ages as well. Because of this discovery, the need to reconsider the stratigraphic validity of these formations and their lithology, nomenclature, structural distribution, facies relations, and graptolite faunas has arisen. The Phi Kappa Formation in most thrust slices has internal stratigraphic continuity despite the intensity of deformation to which it was subjected. As revised herein, the Phi Kappa Formation is restricted to a structurally repeated succession of predominantly black, carbonaceous, graptolitic argillite and shale. Some limy, light-gray-weathering shale occurs in the middle part of the section, and fine-grained locally pebbly quartzite is present at the base. The basal quartzite is here named the Basin Gulch Quartzite Member of the Phi Kappa. The Phi Kappa redefined on a lithologic basis represents the span of Ordovician time from W. B. N. Berry's graptolite zones 2-4 through 15 and also includes approximately 17 m of lithologically identical shale of Early and Middle Silurian age at the top. The lower contact of the formation as revised is tectonic. The Phi Kappa is gradationally overlain by the Trail Creek Formation as restricted herein. Most of the coarser

  9. Development of automated extraction method of biliary tract from abdominal CT volumes based on local intensity structure analysis

    NASA Astrophysics Data System (ADS)

    Koga, Kusuto; Hayashi, Yuichiro; Hirose, Tomoaki; Oda, Masahiro; Kitasaka, Takayuki; Igami, Tsuyoshi; Nagino, Masato; Mori, Kensaku

    2014-03-01

    In this paper, we propose an automated biliary tract extraction method from abdominal CT volumes. The biliary tract is the path by which bile is transported from liver to the duodenum. No extraction method have been reported for the automated extraction of the biliary tract from common contrast CT volumes. Our method consists of three steps including: (1) extraction of extrahepatic bile duct (EHBD) candidate regions, (2) extraction of intrahepatic bile duct (IHBD) candidate regions, and (3) combination of these candidate regions. The IHBD has linear structures and intensities of the IHBD are low in CT volumes. We use a dark linear structure enhancement (DLSE) filter based on a local intensity structure analysis method using the eigenvalues of the Hessian matrix for the IHBD candidate region extraction. The EHBD region is extracted using a thresholding process and a connected component analysis. In the combination process, we connect the IHBD candidate regions to each EHBD candidate region and select a bile duct region from the connected candidate regions. We applied the proposed method to 22 cases of CT volumes. An average Dice coefficient of extraction result was 66.7%.

  10. Storm-related sedimentation influenced by coastal configuration in the stratigraphic record of a tectonically active shelf (Upper Pleistocene Le Castella terrace, Italy)

    NASA Astrophysics Data System (ADS)

    Nalin, Ronald; Massari, Francesco

    2018-03-01

    Analysis of patterns of coastal circulation and sediment dispersal is an essential step for the study of controlling factors influencing the long-term dynamics of coastal systems. Modern settings offer the possibility to monitor relevant parameters over relatively short time spans. However, geological examples complement this perspective by providing a time-averaged record where longer trends and stratigraphically significant processes can be evaluated. This study investigates the shallow marine deposits of Le Castella terrace (Upper Pleistocene, southern Italy) to document how patterns of circulation influenced by coastline configuration can affect the preserved millennial-scale depositional record of a progradational shoreline system. The regressive portion of the Le Castella terrace deposits, developed during a relative sea-level highstand and falling stage, consists of a progradational wedge mainly composed of redistributed skeletal particles of a coeval shallow water carbonate factory. Preservation of the morphology of the paleocoastline and abundant current-related sedimentary structures allow reconstruction of the predominant sediment dispersal dynamics responsible for the formation of this sedimentary wedge. Facies and paleocurrent analysis indicate offshore and alongshore sediment transport modes, consistent with coastal circulation driven by storms normally incident to the shoreline and a sharp change in coastline orientation. This coastal inflection influenced circulation patterns causing flow separation and eddy formation in the lee of the curved coastline. Syndepositional tectonic deformation also affected the architecture of the preserved deposits, controlling the nucleation and development of a clinostratified body and determining localized lateral stratigraphic variability. This study illustrates how transient but recurrent circulation patterns associated with changes in coastal orientation and related to high-energy storm events can leave a

  11. The “unreasonable effectiveness” of stratigraphic and geomorphic experiments

    NASA Astrophysics Data System (ADS)

    Paola, Chris; Straub, Kyle; Mohrig, David; Reinhardt, Liam

    2009-12-01

    -biotic interactions, cohesive effects, stochastic processes, the interplay of structural and geomorphic self-organization, extraction of quantitative process information from landscape and stratigraphic records, and closer interaction between experimentation and theory.

  12. OWL representation of the geologic timescale implementing stratigraphic best practice

    NASA Astrophysics Data System (ADS)

    Cox, S. J.

    2011-12-01

    The geologic timescale is a cornerstone of the earth sciences. Versions are available from many sources, with the following being of particular interest: (i) The official International Stratigraphic Chart (ISC) is maintained by the International Commission for Stratigraphy (ICS), following principles developed over the last 40 years. ICS provides the data underlying the chart as part of a specialized software package, and the chart itself as a PDF using the standard colours; (ii) ITC Enschede has developed a representation of the timescale as a thesaurus in SKOS, used in a Web Map Service delivery system; (iii) JPL's SWEET ontology includes a geologic timescale. This takes full advantage of the capabilities of OWL. However, each of these has limitations - The ISC falls down because of incompatibility with web technologies; - While SKOS supports multilingual labelling, SKOS does not adequately support timescale semantics, in particular since it does not include ordering relationships; - The SWEET version (as of version 2) is not fully aligned to the model used by ICS, in particular not recognizing the role of the Global Boundary Stratotype Sections and Point (GSSP). Furthermore, it is distributed as static documents, rather than through a dynamic API using SPARQL. The representation presented in this paper overcomes all of these limitations as follows: - the timescale model is formulated as an OWL ontology - the ontology is directly derived from the UML representation of the ICS best practice proposed by Cox & Richard [2005], and subsequently included as the Geologic Timescale package in GeoSciML (http://www.geosciml.org); this includes links to GSSPs as per the ICS process - key properties in the ontology are also asserted to be subProperties of SKOS properties (topConcept and broader/narrower relations) in order to support SKOS-based queries; SKOS labelling is used to support multi-lingual naming and synonyms - the International Stratigraphic Chart is implemented

  13. Human brain atlas for automated region of interest selection in quantitative susceptibility mapping: application to determine iron content in deep gray matter structures.

    PubMed

    Lim, Issel Anne L; Faria, Andreia V; Li, Xu; Hsu, Johnny T C; Airan, Raag D; Mori, Susumu; van Zijl, Peter C M

    2013-11-15

    The purpose of this paper is to extend the single-subject Eve atlas from Johns Hopkins University, which currently contains diffusion tensor and T1-weighted anatomical maps, by including contrast based on quantitative susceptibility mapping. The new atlas combines a "deep gray matter parcellation map" (DGMPM) derived from a single-subject quantitative susceptibility map with the previously established "white matter parcellation map" (WMPM) from the same subject's T1-weighted and diffusion tensor imaging data into an MNI coordinate map named the "Everything Parcellation Map in Eve Space," also known as the "EvePM." It allows automated segmentation of gray matter and white matter structures. Quantitative susceptibility maps from five healthy male volunteers (30 to 33 years of age) were coregistered to the Eve Atlas with AIR and Large Deformation Diffeomorphic Metric Mapping (LDDMM), and the transformation matrices were applied to the EvePM to produce automated parcellation in subject space. Parcellation accuracy was measured with a kappa analysis for the left and right structures of six deep gray matter regions. For multi-orientation QSM images, the Kappa statistic was 0.85 between automated and manual segmentation, with the inter-rater reproducibility Kappa being 0.89 for the human raters, suggesting "almost perfect" agreement between all segmentation methods. Segmentation seemed slightly more difficult for human raters on single-orientation QSM images, with the Kappa statistic being 0.88 between automated and manual segmentation, and 0.85 and 0.86 between human raters. Overall, this atlas provides a time-efficient tool for automated coregistration and segmentation of quantitative susceptibility data to analyze many regions of interest. These data were used to establish a baseline for normal magnetic susceptibility measurements for over 60 brain structures of 30- to 33-year-old males. Correlating the average susceptibility with age-based iron concentrations in gray

  14. Human brain atlas for automated region of interest selection in quantitative susceptibility mapping: application to determine iron content in deep gray matter structures

    PubMed Central

    Lim, Issel Anne L.; Faria, Andreia V.; Li, Xu; Hsu, Johnny T.C.; Airan, Raag D.; Mori, Susumu; van Zijl, Peter C. M.

    2013-01-01

    The purpose of this paper is to extend the single-subject Eve atlas from Johns Hopkins University, which currently contains diffusion tensor and T1-weighted anatomical maps, by including contrast based on quantitative susceptibility mapping. The new atlas combines a “deep gray matter parcellation map” (DGMPM) derived from a single-subject quantitative susceptibility map with the previously established “white matter parcellation map” (WMPM) from the same subject’s T1-weighted and diffusion tensor imaging data into an MNI coordinate map named the “Everything Parcellation Map in Eve Space,” also known as the “EvePM.” It allows automated segmentation of gray matter and white matter structures. Quantitative susceptibility maps from five healthy male volunteers (30 to 33 years of age) were coregistered to the Eve Atlas with AIR and Large Deformation Diffeomorphic Metric Mapping (LDDMM), and the transformation matrices were applied to the EvePM to produce automated parcellation in subject space. Parcellation accuracy was measured with a kappa analysis for the left and right structures of six deep gray matter regions. For multi-orientation QSM images, the Kappa statistic was 0.85 between automated and manual segmentation, with the inter-rater reproducibility Kappa being 0.89 for the human raters, suggesting “almost perfect” agreement between all segmentation methods. Segmentation seemed slightly more difficult for human raters on single-orientation QSM images, with the Kappa statistic being 0.88 between automated and manual segmentation, and 0.85 and 0.86 between human raters. Overall, this atlas provides a time-efficient tool for automated coregistration and segmentation of quantitative susceptibility data to analyze many regions of interest. These data were used to establish a baseline for normal magnetic susceptibility measurements for over 60 brain structures of 30- to 33-year-old males. Correlating the average susceptibility with age-based iron

  15. Exploring representations of protein structure for automated remote homology detection and mapping of protein structure space

    PubMed Central

    2014-01-01

    Background Due to rapid sequencing of genomes, there are now millions of deposited protein sequences with no known function. Fast sequence-based comparisons allow detecting close homologs for a protein of interest to transfer functional information from the homologs to the given protein. Sequence-based comparison cannot detect remote homologs, in which evolution has adjusted the sequence while largely preserving structure. Structure-based comparisons can detect remote homologs but most methods for doing so are too expensive to apply at a large scale over structural databases of proteins. Recently, fragment-based structural representations have been proposed that allow fast detection of remote homologs with reasonable accuracy. These representations have also been used to obtain linearly-reducible maps of protein structure space. It has been shown, as additionally supported from analysis in this paper that such maps preserve functional co-localization of the protein structure space. Methods Inspired by a recent application of the Latent Dirichlet Allocation (LDA) model for conducting structural comparisons of proteins, we propose higher-order LDA-obtained topic-based representations of protein structures to provide an alternative route for remote homology detection and organization of the protein structure space in few dimensions. Various techniques based on natural language processing are proposed and employed to aid the analysis of topics in the protein structure domain. Results We show that a topic-based representation is just as effective as a fragment-based one at automated detection of remote homologs and organization of protein structure space. We conduct a detailed analysis of the information content in the topic-based representation, showing that topics have semantic meaning. The fragment-based and topic-based representations are also shown to allow prediction of superfamily membership. Conclusions This work opens exciting venues in designing novel

  16. An expert system executive for automated assembly of large space truss structures

    NASA Technical Reports Server (NTRS)

    Allen, Cheryl L.

    1993-01-01

    Langley Research Center developed a unique test bed for investigating the practical problems associated with the assembly of large space truss structures using robotic manipulators. The test bed is the result of an interdisciplinary effort that encompasses the full spectrum of assembly problems - from the design of mechanisms to the development of software. The automated structures assembly test bed and its operation are described, the expert system executive and its development are detailed, and the planned system evolution is discussed. Emphasis is on the expert system implementation of the program executive. The executive program must direct and reliably perform complex assembly tasks with the flexibility to recover from realistic system errors. The employment of an expert system permits information that pertains to the operation of the system to be encapsulated concisely within a knowledge base. This consolidation substantially reduced code, increased flexibility, eased software upgrades, and realized a savings in software maintenance costs.

  17. Recovering data from historical collections: stratigraphic and spatial reconstruction of the outstanding carnivoran record from the Late Pleistocene Equi cave (Apuane Alps, Italy)

    NASA Astrophysics Data System (ADS)

    Ghezzo, Elena; Palchetti, Alessandro; Rook, Lorenzo

    2014-07-01

    Equi Terme is a hamlet located in northern Tuscany, in Apuan Alps regional Park. An outstanding fossil vertebrate collection housed in Florence is the result of excavations in the Equi cave and shelter during the period 1911-1919. This faunal assemblage (associated with Mousterian artefacts) may be correlated with the middle of MIS 3. All of the specimens recovered at Equi early in the last century were collected with attention to their stratigraphical positions. Detailed field annotation for nearly every specimen allowed us to organize them and attempt a stratigraphical and spatial reconstruction of the fossiliferous deposits. We present the results of the study of the spatial and stratigraphic distribution of the carnivoran species in the Equi cave and shelter, and re-evaluate the taphonomic agents of accumulation and the fossil distribution within the stratigraphic record. In particular, we evaluated the distribution of Panthera pardus, which, unusually for Europe, is abundant in the Equi cave assemblage. This analysis highlights the importance of the re-evaluation of historical collections and allows for future comparisons with data from more recent excavations at the Equi site. The analysis also provides an account of the distribution of carnivorans throughout the stratigraphic record. The constant presence and the predominance of leopards and wolves over lions and smaller carnivorans, allow for evaluations of their ethology and may be related to a short period of sediment accumulation.

  18. Integrated exploration method used in search for stratigraphic traps in Illinois basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caserotti, P.M.

    1989-08-01

    A new oil pool was discovered in Marion County, Illinois, during 1988, using this integrated approach. The discovery is within 2.5 mi of the Salem field, which was discovered in 1938 and has produced more than 387 million bbl of oil. Numerous seismic surveys have been conducted in the area since the Salem field discovery over 50 years ago. Using structure maps developed from the available seismic data, well control, and depositional models, a Ste. Genevieve (middle Mississippian Valmeyeran) prospect was developed on the northeast flank of the Salem anticline. The initial well encountered 8 ft of oil-saturated oolitic limestonemore » in the McClosky zone of the Ste. Genevieve Limestone. Subsequent drilling resulted in four additional oil wells. The size of the reservoir is approximately 120 ac with primary recovery estimated at 200,000 bbl of oil. The depth of the reservoir is 2,250 ft, with an average porosity of 14% and permeability of 300 md. The trapping mechanism is stratigraphic - an oolite bar draped across a gentle nose, which was originally interpreted from the seismic information. Numerous analogous situations exist in the Salem anticline area as well as near other large structures in the basin. An integrated exploration approach can help define these areas and lead to commercial discoveries in mature areas.« less

  19. Development of a machine vision system for automated structural assembly

    NASA Technical Reports Server (NTRS)

    Sydow, P. Daniel; Cooper, Eric G.

    1992-01-01

    Research is being conducted at the LaRC to develop a telerobotic assembly system designed to construct large space truss structures. This research program was initiated within the past several years, and a ground-based test-bed was developed to evaluate and expand the state of the art. Test-bed operations currently use predetermined ('taught') points for truss structural assembly. Total dependence on the use of taught points for joint receptacle capture and strut installation is neither robust nor reliable enough for space operations. Therefore, a machine vision sensor guidance system is being developed to locate and guide the robot to a passive target mounted on the truss joint receptacle. The vision system hardware includes a miniature video camera, passive targets mounted on the joint receptacles, target illumination hardware, and an image processing system. Discrimination of the target from background clutter is accomplished through standard digital processing techniques. Once the target is identified, a pose estimation algorithm is invoked to determine the location, in three-dimensional space, of the target relative to the robots end-effector. Preliminary test results of the vision system in the Automated Structural Assembly Laboratory with a range of lighting and background conditions indicate that it is fully capable of successfully identifying joint receptacle targets throughout the required operational range. Controlled optical bench test results indicate that the system can also provide the pose estimation accuracy to define the target position.

  20. Structural and stratigraphic constraints on tsunamigenic rupture along the frontal Sunda megathrust from MegaTera bathymetric and seismic reflection data

    NASA Astrophysics Data System (ADS)

    Bradley, K. E.; Qin, Y.; Villanueva-Robles, F.; Hananto, N.; Leclerc, F.; Singh, S. C.; Tapponnier, P.; Sieh, K.; Wei, S.; Carton, H. D.; Permana, H.; Avianto, P.; Nugroho, A. B.

    2017-12-01

    The joint EOS/IPG/LIPI 2015 MegaTera expedition collected high-resolution seismic reflection profiles and bathymetric data across the Sunda trench, updip of the Mw7.7, 2010 Mentawai tsunami-earthquake rupture patch. These data reveal rapid lateral variations in both the stratigraphic level of the frontal Sunda megathrust and the vergence of frontal ramp faults. The stratigraphic depth of the megathrust at the deformation front correlates with ramp-thrust vergence and with changes in the basal friction angle inferred by critical-taper wedge theory. Where ramp thrusts verge uniformly seaward and have an average dip of 30°, the megathrust decollement resides atop a high-amplitude reflector that marks the inferred top of pelagic sediments. Where ramp thrusts are bi-vergent (similar throw on both landward- and seaward-vergent faults) and have an average dip of 42°, the decollement is higher, within the incoming clastic sequence, above a seismically transparent unit inferred to represent distal fan muds. Where ramp thrusts are uniformly landward vergent, the decollement sits directly on top of the oceanic crust that forms the bathymetrically prominent, subducting Investigator Ridge. The two, separate regions of large tsunamigenic ground-surface uplift during the 2010 tsunami earthquake that have been inferred from joint inversions of seismic, GPS, and tsunami data (e.g. Yue et al., 2014; Satake et al., 2013) correspond to the areas of frontal bi-vergence in the MegaTera data. We propose that enhanced surface uplift and tsunamigenesis during this event occurred when rupture propagated onto areas where the decollement sits directly above the basal muds of the incoming clastic sequence. Thus we hypothesize that frontal bi-vergence may mark areas of enhanced tsunami hazard posed by small magnitude, shallow megathrust ruptures that propagate to the trench. [Yue, H. et al., 2014, Rupture process of the…, JGR 119 doi:10.1002/2014JB011082; Satake, K. et al., 2013, Tsunami

  1. Semi-Automated Air-Coupled Impact-Echo Method for Large-Scale Parkade Structure.

    PubMed

    Epp, Tyler; Svecova, Dagmar; Cha, Young-Jin

    2018-03-29

    Structural Health Monitoring (SHM) has moved to data-dense systems, utilizing numerous sensor types to monitor infrastructure, such as bridges and dams, more regularly. One of the issues faced in this endeavour is the scale of the inspected structures and the time it takes to carry out testing. Installing automated systems that can provide measurements in a timely manner is one way of overcoming these obstacles. This study proposes an Artificial Neural Network (ANN) application that determines intact and damaged locations from a small training sample of impact-echo data, using air-coupled microphones from a reinforced concrete beam in lab conditions and data collected from a field experiment in a parking garage. The impact-echo testing in the field is carried out in a semi-autonomous manner to expedite the front end of the in situ damage detection testing. The use of an ANN removes the need for a user-defined cutoff value for the classification of intact and damaged locations when a least-square distance approach is used. It is postulated that this may contribute significantly to testing time reduction when monitoring large-scale civil Reinforced Concrete (RC) structures.

  2. Semi-Automated Air-Coupled Impact-Echo Method for Large-Scale Parkade Structure

    PubMed Central

    Epp, Tyler; Svecova, Dagmar; Cha, Young-Jin

    2018-01-01

    Structural Health Monitoring (SHM) has moved to data-dense systems, utilizing numerous sensor types to monitor infrastructure, such as bridges and dams, more regularly. One of the issues faced in this endeavour is the scale of the inspected structures and the time it takes to carry out testing. Installing automated systems that can provide measurements in a timely manner is one way of overcoming these obstacles. This study proposes an Artificial Neural Network (ANN) application that determines intact and damaged locations from a small training sample of impact-echo data, using air-coupled microphones from a reinforced concrete beam in lab conditions and data collected from a field experiment in a parking garage. The impact-echo testing in the field is carried out in a semi-autonomous manner to expedite the front end of the in situ damage detection testing. The use of an ANN removes the need for a user-defined cutoff value for the classification of intact and damaged locations when a least-square distance approach is used. It is postulated that this may contribute significantly to testing time reduction when monitoring large-scale civil Reinforced Concrete (RC) structures. PMID:29596332

  3. Automated NMR structure determination of stereo-array isotope labeled ubiquitin from minimal sets of spectra using the SAIL-FLYA system.

    PubMed

    Ikeya, Teppei; Takeda, Mitsuhiro; Yoshida, Hitoshi; Terauchi, Tsutomu; Jee, Jun-Goo; Kainosho, Masatsune; Güntert, Peter

    2009-08-01

    Stereo-array isotope labeling (SAIL) has been combined with the fully automated NMR structure determination algorithm FLYA to determine the three-dimensional structure of the protein ubiquitin from different sets of input NMR spectra. SAIL provides a complete stereo- and regio-specific pattern of stable isotopes that results in sharper resonance lines and reduced signal overlap, without information loss. Here we show that as a result of the superior quality of the SAIL NMR spectra, reliable, fully automated analyses of the NMR spectra and structure calculations are possible using fewer input spectra than with conventional uniformly 13C/15N-labeled proteins. FLYA calculations with SAIL ubiquitin, using a single three-dimensional "through-bond" spectrum (and 2D HSQC spectra) in addition to the 13C-edited and 15N-edited NOESY spectra for conformational restraints, yielded structures with an accuracy of 0.83-1.15 A for the backbone RMSD to the conventionally determined solution structure of SAIL ubiquitin. NMR structures can thus be determined almost exclusively from the NOESY spectra that yield the conformational restraints, without the need to record many spectra only for determining intermediate, auxiliary data of the chemical shift assignments. The FLYA calculations for this report resulted in 252 ubiquitin structure bundles, obtained with different input data but identical structure calculation and refinement methods. These structures cover the entire range from highly accurate structures to seriously, but not trivially, wrong structures, and thus constitute a valuable database for the substantiation of structure validation methods.

  4. Automated batch fiducial-less tilt-series alignment in Appion using Protomo

    PubMed Central

    Noble, Alex J.; Stagg, Scott M.

    2015-01-01

    The field of electron tomography has benefited greatly from manual and semi-automated approaches to marker-based tilt-series alignment that have allowed for the structural determination of multitudes of in situ cellular structures as well as macromolecular structures of individual protein complexes. The emergence of complementary metal-oxide semiconductor detectors capable of detecting individual electrons has enabled the collection of low dose, high contrast images, opening the door for reliable correlation-based tilt-series alignment. Here we present a set of automated, correlation-based tilt-series alignment, contrast transfer function (CTF) correction, and reconstruction workflows for use in conjunction with the Appion/Leginon package that are primarily targeted at automating structure determination with cryogenic electron microscopy. PMID:26455557

  5. E-novo: an automated workflow for efficient structure-based lead optimization.

    PubMed

    Pearce, Bradley C; Langley, David R; Kang, Jia; Huang, Hongwei; Kulkarni, Amit

    2009-07-01

    An automated E-Novo protocol designed as a structure-based lead optimization tool was prepared through Pipeline Pilot with existing CHARMm components in Discovery Studio. A scaffold core having 3D binding coordinates of interest is generated from a ligand-bound protein structural model. Ligands of interest are generated from the scaffold using an R-group fragmentation/enumeration tool within E-Novo, with their cores aligned. The ligand side chains are conformationally sampled and are subjected to core-constrained protein docking, using a modified CHARMm-based CDOCKER method to generate top poses along with CDOCKER energies. In the final stage of E-Novo, a physics-based binding energy scoring function ranks the top ligand CDOCKER poses using a more accurate Molecular Mechanics-Generalized Born with Surface Area method. Correlation of the calculated ligand binding energies with experimental binding affinities were used to validate protocol performance. Inhibitors of Src tyrosine kinase, CDK2 kinase, beta-secretase, factor Xa, HIV protease, and thrombin were used to test the protocol using published ligand crystal structure data within reasonably defined binding sites. In-house Respiratory Syncytial Virus inhibitor data were used as a more challenging test set using a hand-built binding model. Least squares fits for all data sets suggested reasonable validation of the protocol within the context of observed ligand binding poses. The E-Novo protocol provides a convenient all-in-one structure-based design process for rapid assessment and scoring of lead optimization libraries.

  6. Sequence stratigraphic controls on reservoir characterization and architecture: case study of the Messinian Abu Madi incised-valley fill, Egypt

    NASA Astrophysics Data System (ADS)

    Abdel-Fattah, Mohamed I.; Slatt, Roger M.

    2013-12-01

    Understanding sequence stratigraphy architecture in the incised-valley is a crucial step to understanding the effect of relative sea level changes on reservoir characterization and architecture. This paper presents a sequence stratigraphic framework of the incised-valley strata within the late Messinian Abu Madi Formation based on seismic and borehole data. Analysis of sand-body distribution reveals that fluvial channel sandstones in the Abu Madi Formation in the Baltim Fields, offshore Nile Delta, Egypt, are not randomly distributed but are predictable in their spatial and stratigraphic position. Elucidation of the distribution of sandstones in the Abu Madi incised-valley fill within a sequence stratigraphic framework allows a better understanding of their characterization and architecture during burial. Strata of the Abu Madi Formation are interpreted to comprise two sequences, which are the most complex stratigraphically; their deposits comprise a complex incised valley fill. The lower sequence (SQ1) consists of a thick incised valley-fill of a Lowstand Systems Tract (LST1)) overlain by a Transgressive Systems Tract (TST1) and Highstand Systems Tract (HST1). The upper sequence (SQ2) contains channel-fill and is interpreted as a LST2 which has a thin sandstone channel deposits. Above this, channel-fill sandstone and related strata with tidal influence delineates the base of TST2, which is overlain by a HST2. Gas reservoirs of the Abu Madi Formation (present-day depth ˜3552 m), the Baltim Fields, Egypt, consist of fluvial lowstand systems tract (LST) sandstones deposited in an incised valley. LST sandstones have a wide range of porosity (15 to 28%) and permeability (1 to 5080mD), which reflect both depositional facies and diagenetic controls. This work demonstrates the value of constraining and evaluating the impact of sequence stratigraphic distribution on reservoir characterization and architecture in incised-valley deposits, and thus has an important impact on

  7. Automated fiber placement: Evolution and current demonstrations

    NASA Technical Reports Server (NTRS)

    Grant, Carroll G.; Benson, Vernon M.

    1993-01-01

    The automated fiber placement process has been in development at Hercules since 1980. Fiber placement is being developed specifically for aircraft and other high performance structural applications. Several major milestones have been achieved during process development. These milestones are discussed in this paper. The automated fiber placement process is currently being demonstrated on the NASA ACT program. All demonstration projects to date have focused on fiber placement of transport aircraft fuselage structures. Hercules has worked closely with Boeing and Douglas on these demonstration projects. This paper gives a description of demonstration projects and results achieved.

  8. Automated analysis in generic groups

    NASA Astrophysics Data System (ADS)

    Fagerholm, Edvard

    This thesis studies automated methods for analyzing hardness assumptions in generic group models, following ideas of symbolic cryptography. We define a broad class of generic and symbolic group models for different settings---symmetric or asymmetric (leveled) k-linear groups --- and prove ''computational soundness'' theorems for the symbolic models. Based on this result, we formulate a master theorem that relates the hardness of an assumption to solving problems in polynomial algebra. We systematically analyze these problems identifying different classes of assumptions and obtain decidability and undecidability results. Then, we develop automated procedures for verifying the conditions of our master theorems, and thus the validity of hardness assumptions in generic group models. The concrete outcome is an automated tool, the Generic Group Analyzer, which takes as input the statement of an assumption, and outputs either a proof of its generic hardness or shows an algebraic attack against the assumption. Structure-preserving signatures are signature schemes defined over bilinear groups in which messages, public keys and signatures are group elements, and the verification algorithm consists of evaluating ''pairing-product equations''. Recent work on structure-preserving signatures studies optimality of these schemes in terms of the number of group elements needed in the verification key and the signature, and the number of pairing-product equations in the verification algorithm. While the size of keys and signatures is crucial for many applications, another aspect of performance is the time it takes to verify a signature. The most expensive operation during verification is the computation of pairings. However, the concrete number of pairings is not captured by the number of pairing-product equations considered in earlier work. We consider the question of what is the minimal number of pairing computations needed to verify structure-preserving signatures. We build an

  9. Stratigraphic and structural distribution of reservoirs in Romania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stefanescu, M.O.

    1991-08-01

    In Romania, there are reservoirs at different levels of the whole Cambrian-Pliocene interval, but only some of these levels have the favorable structural conditions to accumulate hydrocarbons in commercial quantities. These levels are the Devonian, Triassic, Middle Jurassic, Lower Cretaceous (locally including the uppermost Jurassic), Eocene, Oligocene-lower Miocene, middle and upper Miocene, and Pliocene. The productive reservoirs are represented either by carbonate rocks (in Devonian, Middle Triassic and uppermost Jurassic-Lower Cretaceous) or by detrital rocks (in Lower and Upper Triassic, Middle Jurassic, Eocene, Oligocene, Miocene, and Pliocene). From the structural point of view, the Romanian territory is characterized by themore » coexistence both of platforms (East European, Scythian, and Moesian platforms) and of the strongly tectonized orogenes (North Dobrogea and Carpathian orogenes). Each importance crust shortening was followed by the accumulation of post-tectonic covers, some of them being folded during subsequently tectonic movements. The youngest post-tectonic cover is common both for the platforms (foreland) and Carpathian orogene, representing the Carpathian foredeep. Producing reservoirs are present in the East European and Moesian platforms, in the outer Carpathian units (Tarcau and Marginal folds nappes) and in certain post-tectonic covers which fill the Carpathian foredeep and the Transylvanian and Pannonian basins. In the platforms, hydrocarbons accumulated both in calcareous and detrital reservoirs, whereas in the Carpathian units and in their reservoirs, whereas in the Carpathian units and in their post-tectonic covers, hydrocarbons accumulated only in detrital reservoirs.« less

  10. Automated web service composition supporting conditional branch structures

    NASA Astrophysics Data System (ADS)

    Wang, Pengwei; Ding, Zhijun; Jiang, Changjun; Zhou, Mengchu

    2014-01-01

    The creation of value-added services by automatic composition of existing ones is gaining a significant momentum as the potential silver bullet in service-oriented architecture. However, service composition faces two aspects of difficulties. First, users' needs present such characteristics as diversity, uncertainty and personalisation; second, the existing services run in a real-world environment that is highly complex and dynamically changing. These difficulties may cause the emergence of nondeterministic choices in the process of service composition, which has gone beyond what the existing automated service composition techniques can handle. According to most of the existing methods, the process model of composite service includes sequence constructs only. This article presents a method to introduce conditional branch structures into the process model of composite service when needed, in order to satisfy users' diverse and personalised needs and adapt to the dynamic changes of real-world environment. UML activity diagrams are used to represent dependencies in composite service. Two types of user preferences are considered in this article, which have been ignored by the previous work and a simple programming language style expression is adopted to describe them. Two different algorithms are presented to deal with different situations. A real-life case is provided to illustrate the proposed concepts and methods.

  11. Development of structural diagram of automated dispatch control system for power consumption at non-ferrous metallurgy enterprises

    NASA Astrophysics Data System (ADS)

    Klyuev, R. V.; Bosikov, I. I.; Madaeva, M. Z.; A-V Turluev, R.

    2018-03-01

    The structural scheme of the automated control system of power consumption at the industrial enterprise is developed in the article. At the non-ferrous metallurgy enterprise, an energy inspection and a rank analysis of the electrical energy consumption of the main processing equipment were carried out. It is established that the enterprises of non-ferrous metallurgy are a complex process system consisting of a set of thousands of jointly functioning technological facilities. For the most effective estimation of power consumption of enterprises, it is reasonable to use the automated system of dispatching control of power consumption (ASDCPC). The paper presents the results of the development of the ASDCPC structural diagram that allows one to perform on-line control and management of the energy and process parameters of the main production units and the enterprise as a whole. As a result of the introduction of ASDCPC at the non-ferrous metallurgy enterprise, the consumed active power was reduced during the peak hours of the load by 20%, the specific electricity consumption - by 14%, the cost of the energy component in the cost of production of hard alloys - by 3%.

  12. Proglacial deltaic landforms and stratigraphic architecture as a proxy for reconstructing past ice-sheet margin positions

    NASA Astrophysics Data System (ADS)

    Dietrich, Pierre; Ghienne, Jean-François; Normandeau, Alexandre; Lajeunesse, Patrick

    2016-04-01

    Deltaic landforms and related stratigraphic architectures are frequently used as proxy for reconstruction of past continental or marine environmental evolutions. Indeed, in addition to autocyclic processes, emplacement of deltaic systems is primarily controlled by changes in sediment supply and relative sea-level (RSL). In our study, we investigated several proglacial deltaic complexes emplaced since the last deglaciation over more than 700 km along the St. Lawrence North Shore (Québec, Canada). Their geomorphic and stratigraphic records allowed us to infer the retreat pattern of the Laurentide Ice Sheet fronts. Field investigation of representative deltaic complexes revealed an archetypal morphostratigraphic evolution forced by the retreat of the ice margin in a context of falling RSL (glacio-isostatic rebound). The base of the stratigraphic successions consists of outwash fan deposits emplaced in the early deglaciation when ice margin stillstanded immediately beyond the depositional area. The middle part of the succession consists of proglacial delta deposits corresponding to the retreat of the ice margin in the hinterland. At that time, glaciogenic supplies allowed an active progradation preventing fluvial entrenchment in spite of the forced regressive context. The upper part of the succession consists of staged shoreline deposits reworking the rim of the proglacial deltas. These deposits mark the retreat of the ice margin from the drainage basin and the subsequent drop in glaciogenics. Important fluvial entrenchment occurred in the same time, though rates of RSL fall were reduced. We generalize this stratigraphic framework by using solely the landforms (from DEM, aerial photographs or satellite images) tied to deltaic complex developments along the St. Lawrence North Shore. This approach permits an integrated study at the scale of the whole basin even where no field data is available. Recognizing the three steps evidenced from the stratigraphic record ads

  13. Application of ground penetrating radar for identification of washover deposits and other stratigraphic features: Assateague Island, MD

    USGS Publications Warehouse

    Zaremba, Nicholas; Smith, Christopher G.; Bernier, Julie C.; Forde, Arnell S.

    2016-01-01

    A combination of ground penetrating radar (GPR) data, core data, and aerial photographs were analyzed to better understand the evolution of two portions of Assateague Island, Maryland. The focus of the study was to investigate the applicability of using GPR data to image washover deposits in the stratigraphic record. High amplitude reflections observed in two shore-perpendicular GPR profiles were correlated to shallow (<1 m) lithologic contacts observed in sediment cores. At these contacts, deposits consisting primarily of quartz sand overlie sediments with organic matter that include degraded plant root or stem material. The underlying organic matter likely represents the vegetated portion of the barrier island that was buried by washover fans deposited during hurricanes Irene (2011) and Sandy (2012), as indicated in high-resolution aerial photographs. The GPR data were able to delineate the washover deposits from the underlying stratigraphic unit; however, the radar data did not resolve finer structures necessary to definitively differentiate washover facies from other sand-rich deposits (e.g., flood-tide deltas and dunes). Other GPR profiles contain reflections that likely correlate to geomorphic features like tidal channels and vegetated zones observed in historical aerial imagery. Burial of these features by overwash fluxes were observed in the aerial imagery and thus the resulting radar sequence is largely interpreted as washover deposits. Deeper, channel-like features that have been infilled were also observed in shore-parallel profiles and these features coincide with scour channels observed in the 1966 aerial photography. Additional sedimentological data are required to determine what role overwash played in the in-filling of these features.

  14. A not-so-big crisis: re-reading Silurian conodont diversity in a sequence-stratigraphic framework

    NASA Astrophysics Data System (ADS)

    Jarochowska, Emilia; Munnecke, Axel

    2016-04-01

    Conodonts are extensively used in Ordovician through Triassic biostratigraphy and fossil-based geochemistry. However, their distribution in rock successions is commonly taken at face value, without taking into account their diverse and poorly understood ecology. Multielement taxonomy, ontogenetic and environmental variability, difficulties in extraction, and relative rarity all contribute to the general lack of quantitative studies on conodont stratigraphic distribution and temporal turnover. With respect to Silurian conodonts, the concept of recurrent conodont extinction events - the so called Ireviken, Mulde and Lau events - has become a standard in the stratigraphic literature. The concept has been proposed based on qualitative observations of local extirpations of open-marine pelagic or nekto-benthic taxa and temporary dominance of shallow-water species in the Silurian succession of the Swedish island of Gotland. These changes coincided with positive carbon isotope excursions, abrupt facies shifts, "blooms" of benthic fauna, and changes in reef communities, which have all been combined into a general view of Silurian bio-geochemical events. This view posits a deterministic, reproducible pattern in Silurian conodont diversity, attributed to recurrent ecological or geochemical conditions. The growing body of sequence-stratigraphic interpretations across these events in Gotland and other sections worldwide indicate that in all cases the Silurian "events" are associated with rapid global regressions. This suggests that faunal changes such as the dominance of shallow-water, low-diversity conodont fauna and the increase of benthic invertebrate diversity and abundance represent predictable consequences of the variation in the completeness of the rock record and preservation potential of different environments. Our studies in Poland and Ukraine indicate that the magnitude of change in the taxonomic composition of conodont assemblages across the middle Silurian global

  15. Computational strategies for the automated design of RNA nanoscale structures from building blocks using NanoTiler.

    PubMed

    Bindewald, Eckart; Grunewald, Calvin; Boyle, Brett; O'Connor, Mary; Shapiro, Bruce A

    2008-10-01

    One approach to designing RNA nanoscale structures is to use known RNA structural motifs such as junctions, kissing loops or bulges and to construct a molecular model by connecting these building blocks with helical struts. We previously developed an algorithm for detecting internal loops, junctions and kissing loops in RNA structures. Here we present algorithms for automating or assisting many of the steps that are involved in creating RNA structures from building blocks: (1) assembling building blocks into nanostructures using either a combinatorial search or constraint satisfaction; (2) optimizing RNA 3D ring structures to improve ring closure; (3) sequence optimisation; (4) creating a unique non-degenerate RNA topology descriptor. This effectively creates a computational pipeline for generating molecular models of RNA nanostructures and more specifically RNA ring structures with optimized sequences from RNA building blocks. We show several examples of how the algorithms can be utilized to generate RNA tecto-shapes.

  16. Computational strategies for the automated design of RNA nanoscale structures from building blocks using NanoTiler☆

    PubMed Central

    Bindewald, Eckart; Grunewald, Calvin; Boyle, Brett; O’Connor, Mary; Shapiro, Bruce A.

    2013-01-01

    One approach to designing RNA nanoscale structures is to use known RNA structural motifs such as junctions, kissing loops or bulges and to construct a molecular model by connecting these building blocks with helical struts. We previously developed an algorithm for detecting internal loops, junctions and kissing loops in RNA structures. Here we present algorithms for automating or assisting many of the steps that are involved in creating RNA structures from building blocks: (1) assembling building blocks into nanostructures using either a combinatorial search or constraint satisfaction; (2) optimizing RNA 3D ring structures to improve ring closure; (3) sequence optimisation; (4) creating a unique non-degenerate RNA topology descriptor. This effectively creates a computational pipeline for generating molecular models of RNA nanostructures and more specifically RNA ring structures with optimized sequences from RNA building blocks. We show several examples of how the algorithms can be utilized to generate RNA tecto-shapes. PMID:18838281

  17. Evaluation of stereo-array isotope labeling (SAIL) patterns for automated structural analysis of proteins with CYANA.

    PubMed

    Ikeya, Teppei; Terauchi, Tsutomu; Güntert, Peter; Kainosho, Masatsune

    2006-07-01

    Recently we have developed the stereo-array isotope labeling (SAIL) technique to overcome the conventional molecular size limitation in NMR protein structure determination by employing complete stereo- and regiospecific patterns of stable isotopes. SAIL sharpens signals and simplifies spectra without the loss of requisite structural information, thus making large classes of proteins newly accessible to detailed solution structure determination. The automated structure calculation program CYANA can efficiently analyze SAIL-NOESY spectra and calculate structures without manual analysis. Nevertheless, the original SAIL method might not be capable of determining the structures of proteins larger than 50 kDa or membrane proteins, for which the spectra are characterized by many broadened and overlapped peaks. Here we have carried out simulations of new SAIL patterns optimized for minimal relaxation and overlap, to evaluate the combined use of SAIL and CYANA for solving the structures of larger proteins and membrane proteins. The modified approach reduces the number of peaks to nearly half of that observed with uniform labeling, while still yielding well-defined structures and is expected to enable NMR structure determinations of these challenging systems.

  18. Biothems: Sequence stratigraphic units and their implications for regional tectono-stratigraphic interpretations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lane, H.R.; Frye, M.W.; Couples, G.D.

    1992-01-01

    Biothems are regional wedge- or lens-shaped bodies of strata that are bounded shelfward or cratonward by paleontologically recognizable unconformities; generally thicken on marine shelves, where they are typically conformable with underlying and overlying biothems; are commonly thinner or represent starved sequences further basinward; and in their most basinward extent, are either bounded by biostratigraphically recognizable unconformities or are conformable with underlying and overlying biothems. As recognized to date, biothems have a logical distribution of faunal and floral components, as well as facies groupings that represent internally consistent and logical sequences of depositional environments. A west-to-east transect within the North Americanmore » Mississippian System which extends from the Basin and Range Province, across the Transcontinental Arch (TA), into the Anadarko Basin, was constructed to demonstrate the regional distribution and tectono-stratigraphic significance of biothems relative to the axis of the TA. The relationships portrayed on the transect, tied to an understanding of North American Mississippian paleogeography, imply that biothems deposited during relative highstand events on one flank of the TA are time-equivalent to biothems deposited during relative lowstand events on the opposite flank of the TA. This distribution is interpreted to have been controlled by intraplate tectonic events that formed piano key basins along the flanks of the TA. The spatial patterns of these basins are not consistent with published models of basin evolution. A further conclusion is that the lack of coincident, transgressive or regressive Mississippian biothems on either flank of the TA suggests that it is inadvisable to impose the Mississippi Valley-derived eustasy curve on western flank depositional sequences.« less

  19. Managing expectations: assessment of chemistry databases generated by automated extraction of chemical structures from patents.

    PubMed

    Senger, Stefan; Bartek, Luca; Papadatos, George; Gaulton, Anna

    2015-12-01

    First public disclosure of new chemical entities often takes place in patents, which makes them an important source of information. However, with an ever increasing number of patent applications, manual processing and curation on such a large scale becomes even more challenging. An alternative approach better suited for this large corpus of documents is the automated extraction of chemical structures. A number of patent chemistry databases generated by using the latter approach are now available but little is known that can help to manage expectations when using them. This study aims to address this by comparing two such freely available sources, SureChEMBL and IBM SIIP (IBM Strategic Intellectual Property Insight Platform), with manually curated commercial databases. When looking at the percentage of chemical structures successfully extracted from a set of patents, using SciFinder as our reference, 59 and 51 % were also found in our comparison in SureChEMBL and IBM SIIP, respectively. When performing this comparison with compounds as starting point, i.e. establishing if for a list of compounds the databases provide the links between chemical structures and patents they appear in, we obtained similar results. SureChEMBL and IBM SIIP found 62 and 59 %, respectively, of the compound-patent pairs obtained from Reaxys. In our comparison of automatically generated vs. manually curated patent chemistry databases, the former successfully provided approximately 60 % of links between chemical structure and patents. It needs to be stressed that only a very limited number of patents and compound-patent pairs were used for our comparison. Nevertheless, our results will hopefully help to manage expectations of users of patent chemistry databases of this type and provide a useful framework for more studies like ours as well as guide future developments of the workflows used for the automated extraction of chemical structures from patents. The challenges we have encountered

  20. Altering user' acceptance of automation through prior automation exposure.

    PubMed

    Bekier, Marek; Molesworth, Brett R C

    2017-06-01

    Air navigation service providers worldwide see increased use of automation as one solution to overcome the capacity constraints imbedded in the present air traffic management (ATM) system. However, increased use of automation within any system is dependent on user acceptance. The present research sought to determine if the point at which an individual is no longer willing to accept or cooperate with automation can be manipulated. Forty participants underwent training on a computer-based air traffic control programme, followed by two ATM exercises (order counterbalanced), one with and one without the aid of automation. Results revealed after exposure to a task with automation assistance, user acceptance of high(er) levels of automation ('tipping point') decreased; suggesting it is indeed possible to alter automation acceptance. Practitioner Summary: This paper investigates whether the point at which a user of automation rejects automation (i.e. 'tipping point') is constant or can be manipulated. The results revealed after exposure to a task with automation assistance, user acceptance of high(er) levels of automation decreased; suggesting it is possible to alter automation acceptance.

  1. RCrane: semi-automated RNA model building.

    PubMed

    Keating, Kevin S; Pyle, Anna Marie

    2012-08-01

    RNA crystals typically diffract to much lower resolutions than protein crystals. This low-resolution diffraction results in unclear density maps, which cause considerable difficulties during the model-building process. These difficulties are exacerbated by the lack of computational tools for RNA modeling. Here, RCrane, a tool for the partially automated building of RNA into electron-density maps of low or intermediate resolution, is presented. This tool works within Coot, a common program for macromolecular model building. RCrane helps crystallographers to place phosphates and bases into electron density and then automatically predicts and builds the detailed all-atom structure of the traced nucleotides. RCrane then allows the crystallographer to review the newly built structure and select alternative backbone conformations where desired. This tool can also be used to automatically correct the backbone structure of previously built nucleotides. These automated corrections can fix incorrect sugar puckers, steric clashes and other structural problems.

  2. Automated batch fiducial-less tilt-series alignment in Appion using Protomo.

    PubMed

    Noble, Alex J; Stagg, Scott M

    2015-11-01

    The field of electron tomography has benefited greatly from manual and semi-automated approaches to marker-based tilt-series alignment that have allowed for the structural determination of multitudes of in situ cellular structures as well as macromolecular structures of individual protein complexes. The emergence of complementary metal-oxide semiconductor detectors capable of detecting individual electrons has enabled the collection of low dose, high contrast images, opening the door for reliable correlation-based tilt-series alignment. Here we present a set of automated, correlation-based tilt-series alignment, contrast transfer function (CTF) correction, and reconstruction workflows for use in conjunction with the Appion/Leginon package that are primarily targeted at automating structure determination with cryogenic electron microscopy. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. I-TASSER: fully automated protein structure prediction in CASP8.

    PubMed

    Zhang, Yang

    2009-01-01

    The I-TASSER algorithm for 3D protein structure prediction was tested in CASP8, with the procedure fully automated in both the Server and Human sections. The quality of the server models is close to that of human ones but the human predictions incorporate more diverse templates from other servers which improve the human predictions in some of the distant homology targets. For the first time, the sequence-based contact predictions from machine learning techniques are found helpful for both template-based modeling (TBM) and template-free modeling (FM). In TBM, although the accuracy of the sequence based contact predictions is on average lower than that from template-based ones, the novel contacts in the sequence-based predictions, which are complementary to the threading templates in the weakly or unaligned regions, are important to improve the global and local packing in these regions. Moreover, the newly developed atomic structural refinement algorithm was tested in CASP8 and found to improve the hydrogen-bonding networks and the overall TM-score, which is mainly due to its ability of removing steric clashes so that the models can be generated from cluster centroids. Nevertheless, one of the major issues of the I-TASSER pipeline is the model selection where the best models could not be appropriately recognized when the correct templates are detected only by the minority of the threading algorithms. There are also problems related with domain-splitting and mirror image recognition which mainly influences the performance of I-TASSER modeling in the FM-based structure predictions. Copyright 2009 Wiley-Liss, Inc.

  4. The role of integrated high resolution stratigraphic and geophysic surveys for groundwater modelling

    NASA Astrophysics Data System (ADS)

    Margiotta, S.; Mazzone, F.; Negri, S.; Calora, M.

    2008-10-01

    This work sets out a methodology of integrated geological, hydrogeological and geophysical surveys for the characterization of contaminated sites. The flow model of the shallow aquifer in the Brindisi area (recognized to be at significant environmental risk by the Italian government) and the impact of an antrophic structure on the groundwater flow have been evaluated. The stratigraphic and hydrogeological targets used for the calibration phase of the flow model provide a means of assessing calibration quality. The good calibration of the model point out the key role of a detailed knowledge of the physical-stratigraphycal attributes of the area to be studied and field data collection. Geoelectrical tomography focus the attention on an area resulted of particular interest by the flow model obtained. This method permit to reconstruct in detail the lateral and vertical lithological variations in the geological formations improving the spatial resolution of the data and consequently the scale of observation. Besides, anomaly resistivity values have been correlated with pollution. Chemical analysis have confirmed this correlation.

  5. Automated protein structure modeling in CASP9 by I-TASSER pipeline combined with QUARK-based ab initio folding and FG-MD-based structure refinement

    PubMed Central

    Xu, Dong; Zhang, Jian; Roy, Ambrish; Zhang, Yang

    2011-01-01

    I-TASSER is an automated pipeline for protein tertiary structure prediction using multiple threading alignments and iterative structure assembly simulations. In CASP9 experiments, two new algorithms, QUARK and FG-MD, were added to the I-TASSER pipeline for improving the structural modeling accuracy. QUARK is a de novo structure prediction algorithm used for structure modeling of proteins that lack detectable template structures. For distantly homologous targets, QUARK models are found useful as a reference structure for selecting good threading alignments and guiding the I-TASSER structure assembly simulations. FG-MD is an atomic-level structural refinement program that uses structural fragments collected from the PDB structures to guide molecular dynamics simulation and improve the local structure of predicted model, including hydrogen-bonding networks, torsion angles and steric clashes. Despite considerable progress in both the template-based and template-free structure modeling, significant improvements on protein target classification, domain parsing, model selection, and ab initio folding of beta-proteins are still needed to further improve the I-TASSER pipeline. PMID:22069036

  6. Stratigraphic architecture of bedrock reference section, Victoria Crater, Meridiani Planum, Mars

    USGS Publications Warehouse

    Edgar, Lauren A.; Grotzinger, John P.; Hayes, Alex G.; Rubin, David M.; Squyres, Steve W.; Bell, James F.; Herkenhoff, Ken E.

    2012-01-01

    The Mars Exploration Rover Opportunity has investigated bedrock outcrops exposed in several craters at Meridiani Planum, Mars, in an effort to better understand the role of surface processes in its geologic history. Opportunity has recently completed its observations of Victoria crater, which is 750 m in diameter and exposes cliffs up to ~15 m high. The plains surrounding Victoria crater are ~10 m higher in elevation than those surrounding the previously explored Endurance crater, indicating that the Victoria crater exposes a stratigraphically higher section than does the Endurance crater; however, Victoria strata overlap in elevation with the rocks exposed at the Erebus crater. Victoria crater has a well-developed geomorphic pattern of promontories and embayments that define the crater wall and that reveal thick bedsets (3–7m) of large-scale cross-bedding, interpreted as fossil eolian dunes. Opportunity was able to drive into the crater at Duck Bay, located on the western margin of Victoria crater. Data from the Microscopic Imager and Panoramic Camera reveal details about the structures, textures, and depositional and diagenetic events that influenced the Victoria bedrock. A lithostratigraphic subdivision of bedrock units was enabled by the presence of a light-toned band that lines much of the upper rim of the crater. In ascending order, three stratigraphic units are named Lyell, Smith, and Steno; Smith is the light-toned band. In the Reference Section exposed along the ingress path at Duck Bay, Smith is interpreted to represent a zone of diagenetic recrystallization; however, its upper contact also coincides with a primary erosional surface. Elsewhere in the crater the diagenetic band crosscuts the physical stratigraphy. Correlation with strata present at nearby promontory Cape Verde indicates that there is an erosional surface at the base of the cliff face that corresponds to the erosional contact below Steno. The erosional contact at the base of Cape Verde

  7. Correlation of coal beds, coal zones, and key stratigraphic units in the Pennsylvanian rocks of eastern Kentucky

    USGS Publications Warehouse

    Rice, Charles L.; Smith, J. Hiram

    1980-01-01

    The Pennsylvanian rocks of the eastern Kentucky coal field unlderlie an area of about 27,000 square kilometers (see index map). Largely because of the size and stratigraphic complexity of the area, Huddle and others (1963, p. 31) divided it into six coal reserve districts (unofficial), utilizing state and county lines as well as geologic features, drainage areas, and cola producing areas. This division is followed herein because, in general, each of these districts has a characteristic stratigraphic nomenclature, particularly as related to coal bed names. The six districts shown on the index mat, are the Princess, Licking River, Big Sandy, Hazard, Southwestern, and Upper Cumberland River; the Upper Cumberland River district has been divided into the Harlan and Middlesboro subdistricts. 

  8. Complacency and Automation Bias in the Use of Imperfect Automation.

    PubMed

    Wickens, Christopher D; Clegg, Benjamin A; Vieane, Alex Z; Sebok, Angelia L

    2015-08-01

    We examine the effects of two different kinds of decision-aiding automation errors on human-automation interaction (HAI), occurring at the first failure following repeated exposure to correctly functioning automation. The two errors are incorrect advice, triggering the automation bias, and missing advice, reflecting complacency. Contrasts between analogous automation errors in alerting systems, rather than decision aiding, have revealed that alerting false alarms are more problematic to HAI than alerting misses are. Prior research in decision aiding, although contrasting the two aiding errors (incorrect vs. missing), has confounded error expectancy. Participants performed an environmental process control simulation with and without decision aiding. For those with the aid, automation dependence was created through several trials of perfect aiding performance, and an unexpected automation error was then imposed in which automation was either gone (one group) or wrong (a second group). A control group received no automation support. The correct aid supported faster and more accurate diagnosis and lower workload. The aid failure degraded all three variables, but "automation wrong" had a much greater effect on accuracy, reflecting the automation bias, than did "automation gone," reflecting the impact of complacency. Some complacency was manifested for automation gone, by a longer latency and more modest reduction in accuracy. Automation wrong, creating the automation bias, appears to be a more problematic form of automation error than automation gone, reflecting complacency. Decision-aiding automation should indicate its lower degree of confidence in uncertain environments to avoid the automation bias. © 2015, Human Factors and Ergonomics Society.

  9. Automated retrieval of forest structure variables based on multi-scale texture analysis of VHR satellite imagery

    NASA Astrophysics Data System (ADS)

    Beguet, Benoit; Guyon, Dominique; Boukir, Samia; Chehata, Nesrine

    2014-10-01

    The main goal of this study is to design a method to describe the structure of forest stands from Very High Resolution satellite imagery, relying on some typical variables such as crown diameter, tree height, trunk diameter, tree density and tree spacing. The emphasis is placed on the automatization of the process of identification of the most relevant image features for the forest structure retrieval task, exploiting both spectral and spatial information. Our approach is based on linear regressions between the forest structure variables to be estimated and various spectral and Haralick's texture features. The main drawback of this well-known texture representation is the underlying parameters which are extremely difficult to set due to the spatial complexity of the forest structure. To tackle this major issue, an automated feature selection process is proposed which is based on statistical modeling, exploring a wide range of parameter values. It provides texture measures of diverse spatial parameters hence implicitly inducing a multi-scale texture analysis. A new feature selection technique, we called Random PRiF, is proposed. It relies on random sampling in feature space, carefully addresses the multicollinearity issue in multiple-linear regression while ensuring accurate prediction of forest variables. Our automated forest variable estimation scheme was tested on Quickbird and Pléiades panchromatic and multispectral images, acquired at different periods on the maritime pine stands of two sites in South-Western France. It outperforms two well-established variable subset selection techniques. It has been successfully applied to identify the best texture features in modeling the five considered forest structure variables. The RMSE of all predicted forest variables is improved by combining multispectral and panchromatic texture features, with various parameterizations, highlighting the potential of a multi-resolution approach for retrieving forest structure

  10. Stratigraphic framework and coal correlation of the Upper Cretaceous Fruitland Formation, Bisti-Ah-Shi-Sle-Pah area, San Juan Basin, New Mexico

    USGS Publications Warehouse

    Flores, Romeo M.; Erpenbeck, Michael F.

    1982-01-01

    This report illustrates and describes the detailed stratigraphic framework and coal correlation of the Upper Cretaceous Fruitland Formation exposed in isolated badlands and along washes within a 20-mile outcrop belt in the Bisti-Ah-Shi-Sle-Pah area, southwestern San Juan Basin, Nex Mexico (see index). The stratigraphic framework showing the vertical and lateral distributions of rock types and the lateral continuity of coal beds is illustrated in cross sections. The cross sections were constructed from 112 stratigraphic sections measured at an average distance of 0.4 mi apart. Each section contained key marker beds (sandstone, coal, and tonstein) that were physically traced to adjacent sections. Each measured section was "hung" on multiple marker beds arranged in a geometric best-fit method that accounts for the differential compaction and facies associations of the deposits. 

  11. Snow stratigraphic heterogeneity within ground-based passive microwave radiometer footprints: Implications for emission modeling

    NASA Astrophysics Data System (ADS)

    Rutter, Nick; Sandells, Mel; Derksen, Chris; Toose, Peter; Royer, Alain; Montpetit, Benoit; Langlois, Alex; Lemmetyinen, Juha; Pulliainen, Jouni

    2014-03-01

    Two-dimensional measurements of snowpack properties (stratigraphic layering, density, grain size, and temperature) were used as inputs to the multilayer Helsinki University of Technology (HUT) microwave emission model at a centimeter-scale horizontal resolution, across a 4.5 m transect of ground-based passive microwave radiometer footprints near Churchill, Manitoba, Canada. Snowpack stratigraphy was complex (between six and eight layers) with only three layers extending continuously throughout the length of the transect. Distributions of one-dimensional simulations, accurately representing complex stratigraphic layering, were evaluated using measured brightness temperatures. Large biases (36 to 68 K) between simulated and measured brightness temperatures were minimized (-0.5 to 0.6 K), within measurement accuracy, through application of grain scaling factors (2.6 to 5.3) at different combinations of frequencies, polarizations, and model extinction coefficients. Grain scaling factors compensated for uncertainty relating optical specific surface area to HUT effective grain size inputs and quantified relative differences in scattering and absorption properties of various extinction coefficients. The HUT model required accurate representation of ice lenses, particularly at horizontal polarization, and large grain scaling factors highlighted the need to consider microstructure beyond the size of individual grains. As variability of extinction coefficients was strongly influenced by the proportion of large (hoar) grains in a vertical profile, it is important to consider simulations from distributions of one-dimensional profiles rather than single profiles, especially in sub-Arctic snowpacks where stratigraphic variability can be high. Model sensitivity experiments suggested that the level of error in field measurements and the new methodological framework used to apply them in a snow emission model were satisfactory. Layer amalgamation showed that a three

  12. Subsurface stratigraphic cross sections of cretaceous and lower tertiary rocks in the Wind River Basin, central Wyoming: Chapter 9 in Petroleum systems and geologic assessment of oil and gas resources in the Wind River Basin Province, Wyoming

    USGS Publications Warehouse

    Finn, Thomas M.

    2007-01-01

    The stratigraphic cross sections presented in this report were constructed as part of a project conducted by the U.S. Geological Survey to characterize and evaluate the undiscovered oil and gas resources of the Wind River Basin (WRB) in central Wyoming. The primary purpose of the cross sections is to show the stratigraphic framework and facies relations of Cretaceous and lower Tertiary rocks in this large, intermontane structural and sedimentary basin, which formed in the Rocky Mountain foreland during the Laramide orogeny (Late Cretaceous through early Eocene time). The WRB is nearly 200 miles (mi) long, 70 mi wide, and encompasses about 7,400 square miles (mi2) (fig. 1). The basin is structurally bounded by the Owl Creek and Bighorn Mountains on the north, the Casper arch on the east, the Granite Mountains on the south, and the Wind River Range on the west.

  13. Pennsylvanian Tyler stratigraphic seismic concepts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moore, C.E.; Archer, R.J.

    Recent drilling in the Rattler Butte area of central Montana has renewed interest in the Pennsylvanian Tyler Formation as a drilling objective. New production in this area, coupled with the surrounding well density, provides an ideal situation for further development of Tyler stratigraphic-seismic exploration concepts and methods. Both geologic and geophysical Tyler thickness maps have proven to be useful tools in delineating eroded Heath and subsequent lower Tyler deposition. Seismic modeling has revealed a series of possible Tyler-Heath erosional edge characteristics, providing another tool for Tyler-Heath boundary definition. In modeling specific seismic sand signatures, it was found that seismic charactermore » and amplitude are dependent upon both formation thickness and lithology. Detailed mapping of the study area also revealed a new environmental interpretation of the Tyler. Unlike the fluvial system to the north, the Tyler regime in the Rattler Butte area appears to have fluctuated among fluvial, deltaic, and marine systems. Two hydrocarbon occurrence patterns have been noted within the Tyler: (1) although reservoir quality sands are present throughout the Tyler, those within the lower Tyler are more likely to contain hydrocarbons, and (2) close proximity to the Tyler-Heath erosional edge increases the chances of discovering oil-filled Tyler sands. Combined use of these exploration tools should greatly enhance the chances for successful lower Tyler exploration.« less

  14. Cenozoic Structural and Stratigraphic Evolution of the Ulukışla and Sivas Basins (Central and Eastern Turkey)

    NASA Astrophysics Data System (ADS)

    Gürer, Derya; Darin, Michael H.; van Hinsbergen, Douwe J. J.; Umhoefer, Paul J.

    2017-04-01

    Because subduction is a destructive process, the surface record of subduction-dominated systems is naturally incomplete. Sedimentary basins may hold the most complete record of processes related to subduction, accretion, collision, and ocean closure, and thus provide key information for understanding the kinematic evolution of orogens. In central and eastern Anatolia, the Late Cretaceous-Paleogene stratigraphic record of the Ulukışla and Sivas basins supports the hypothesis that these once formed a contiguous basin. Importantly, their age and geographic positions relative to their very similar basement units and ahead of the Arabian indenter provide a critical record of pre-, syn- and post-collisional processes in the Anatolian Orogen. The Ulukışla-Sivas basin was dissected and translated along the major left-lateral Ecemiş fault zone. Since then, the basins on either side of the fault evolved independently, with considerably more plate convergence accommodated to the east in the Sivas region (eastern Anatolia) than in the Ulukışla region (central Anatolia). This led to the deformation of marine sediments and underlying ophiolites and structural growth of the Sivas Fold-and-Thrust Belt (SSFTB) since latest Eocene time, which played a major role in marine basin isolation and disconnection, along with a regionally important transition to continental conditions with evaporite deposition starting in the early Oligocene. We use geologic mapping, fault kinematic analysis, paleomagnetism, apatite fission track (AFT) thermochronology, and 40Ar/39Ar geochronology to characterize the architecture, deformation style, and structural evolution of the region. In the Ulukışla basin, dominantly E-W trending normal faults became folded or inverted due to N-S contraction since the Lutetian (middle Eocene). This was accompanied by significant counter-clockwise rotations, and post-Lutetian burial of the Niǧde Massif along the transpressional Ecemiş fault zone. Since Miocene

  15. Tyler sandstones (Pennsylvanian), Dickinson area, North Dakota: a 24-million barrel soil-zone stratigraphic trap

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Land, C.B.

    Approximately 24 million bbl of recoverable oil has been found in stratigraphic traps in the lower Pennsylvanian Tyler formation at the Dickinson, South Heart, and E. Green River Fields, Stark County, North Dakota. Production is from a multiple sequence of quartzose sandstones 5 to 18 ft (1.5 to 5 m) thick deposited as barrier islands along regressive shorelines. A typical vertical sequence is given. Throughout much of the subject area, porosity and permeability in the sandstones have been greatly reduced or completely destroyed by development of caliche paleosols. In the western part, the caliche consists of gray to brown limestonemore » nodules or nodular layers of limestone in the sandstones and contains abundant pyrite. It is estimated that the caliche destroys as much as 50% of the potential reservoir rock in the area and is an essential factor in the stratigraphic entrapment of the petroleum accumulations by providing an eastern (updip) barrier to migration.« less

  16. Middle Tertiary stratigraphic sequences of the San Joaquin Basin, California: Chapter 6 in Petroleum systems and geologic assessment of oil and gas in the San Joaquin Basin Province, California

    USGS Publications Warehouse

    Johnson, Cari L.; Graham, Stephan A.

    2007-01-01

    An integrated database of outcrop studies, borehole logs, and seismic-reflection profiles is used to divide Eocene through Miocene strata of the central and southern San Joaquin Basin, California, into a framework of nine stratigraphic sequences. These third- and higher-order sequences (<3 m.y. duration) comprise the principal intervals for petroleum assessment for the basin, including key reservoir and source rock intervals. Important characteristics of each sequence are discussed, including distribution and stratigraphic relationships, sedimentary facies, regional correlation, and age relations. This higher-order stratigraphic packaging represents relatively short-term fluctuations in various forcing factors including climatic effects, changes in sediment supply, local and regional tectonism, and fluctuations in global eustatic sea level. These stratigraphic packages occur within the context of second-order stratigraphic megasequences, which mainly reflect long-term tectonic basin evolution. Despite more than a century of petroleum exploration in the San Joaquin Basin, many uncertainties remain regarding the age, correlation, and origin of the third- and higher-order sequences. Nevertheless, a sequence stratigraphic approach allows definition of key intervals based on genetic affinity rather than purely lithostratigraphic relationships, and thus is useful for reconstructing the multiphase history of this basin, as well as understanding its petroleum systems.

  17. Space power subsystem automation technology

    NASA Technical Reports Server (NTRS)

    Graves, J. R. (Compiler)

    1982-01-01

    The technology issues involved in power subsystem automation and the reasonable objectives to be sought in such a program were discussed. The complexities, uncertainties, and alternatives of power subsystem automation, along with the advantages from both an economic and a technological perspective were considered. Whereas most spacecraft power subsystems now use certain automated functions, the idea of complete autonomy for long periods of time is almost inconceivable. Thus, it seems prudent that the technology program for power subsystem automation be based upon a growth scenario which should provide a structured framework of deliberate steps to enable the evolution of space power subsystems from the current practice of limited autonomy to a greater use of automation with each step being justified on a cost/benefit basis. Each accomplishment should move toward the objectives of decreased requirement for ground control, increased system reliability through onboard management, and ultimately lower energy cost through longer life systems that require fewer resources to operate and maintain. This approach seems well-suited to the evolution of more sophisticated algorithms and eventually perhaps even the use of some sort of artificial intelligence. Multi-hundred kilowatt systems of the future will probably require an advanced level of autonomy if they are to be affordable and manageable.

  18. Stratigraphic framework of Holocene volcaniclastic deposits, Akutan Volcano, east-central Aleutian Islands, Alaska

    USGS Publications Warehouse

    Waythomas, C.F.

    1999-01-01

    Akutan Volcano is one of the most active volcanoes in the Aleutian arc, but until recently little was known about its history and eruptive character. Following a brief but sustained period of intense seismic activity in March 1996, the Alaska Volcano Observatory began investigating the geology of the volcano and evaluating potential volcanic hazards that could affect residents of Akutan Island. During these studies new information was obtained about the Holocene eruptive history of the volcano on the basis of stratigraphic studies of volcaniclastic deposits and radiocarbon dating of associated buried soils and peat. A black, scoria-bearing, lapilli tephra, informally named the 'Akutan tephra,' is up to 2 m thick and is found over most of the island, primarily east of the volcano summit. Six radiocarbon ages on the humic fraction of soil A-horizons beneath the tephra indicate that the Akutan tephra was erupted approximately 1611 years B.P. At several locations the Akutan tephra is within a conformable stratigraphic sequence of pyroclastic-flow and lahar deposits that are all part of the same eruptive sequence. The thickness, widespread distribution, and conformable stratigraphic association with overlying pyroclastic-flow and lahar deposits indicate that the Akutan tephra likely records a major eruption of Akutan Volcano that may have formed the present summit caldera. Noncohesive lahar and pyroclastic-flow deposits that predate the Akutan tephra occur in the major valleys that head on the volcano and are evidence for six to eight earlier Holocene eruptions. These eruptions were strombolian to subplinian events that generated limited amounts of tephra and small pyroclastic flows that extended only a few kilometers from the vent. The pyroclastic flows melted snow and ice on the volcano flanks and formed lahars that traveled several kilometers down broad, formerly glaciated valleys, reaching the coast as thin, watery, hyperconcentrated flows or water floods. Slightly

  19. Implications of new stratigraphic data on volcanic hazard assessment for Nisyros volcano, Greece

    NASA Astrophysics Data System (ADS)

    Volentik, A.; Vanderkluysen, L.; Principe, C.; Hernandez, J.; Hunziker, J. C.

    2003-04-01

    The active quaternary Nisyros volcano, at the eastern end of the Aegean volcanic arc, is composed of a succession of lava flows, tephra layers and interbedded epiclastic deposits. The volcano is topped by a recent caldera, on average 4 km in diameter and 200 m in depth. A detailed geological map including 35 stratigraphic units (lava flows, tephra layers and epiclastic deposits) has been recently completed at the 1:10'000 scale, based on new stratigraphical data. Based on the identification of new plinian sequences (Lakki and Melisseri pyroclastic series) in the lowermost section of the reconstructed stratigraphical succession, on the re-interpretation of previously described deposits and on the discovery of eruptive facies, we construct a set of hazard maps for volcanic events at Nisyros. Sequences of sub-marine lavas to subaerial epiclastites combined with the occurrence of a marine terrace deposit in the north-western sector of the island highlight the potential for rapid vertical movements, in particular in the area of Mandraki. A period of intense off-centred strombolian to phreatomagmatic activity occurred in quite recent times on Nisyros along the major tectonic trends (N^o030, No070, N^o120 and N^o340), building up several scoria cones and tuff cones all around the island. A number of these tectonic trends are still active, as demonstrated by faults cutting through recent deposits (including the youngest deposits of the hydrothermal eruptions, inside the present caldera of Nisyros). This implies that not only intra-caldera phreatic eruptions, but also potential magmatic eruption may occur along the island’s major zones of weakness, with increased hazards where magma/water interaction may take place. Finally a newly recognized debris avalanche deposit (the so-called Vunàri debris avalanche), affecting a wide sector in the northern part of the island, unveils a new type of volcanic hazard on Nisyros, related to flank collapse and destruction of the

  20. Towards Automated Screening of Two-dimensional Crystals

    PubMed Central

    Cheng, Anchi; Leung, Albert; Fellmann, Denis; Quispe, Joel; Suloway, Christian; Pulokas, James; Carragher, Bridget; Potter, Clinton S.

    2007-01-01

    Screening trials to determine the presence of two-dimensional (2D) protein crystals suitable for three-dimensional structure determination using electron crystallography is a very labor-intensive process. Methods compatible with fully automated screening have been developed for the process of crystal production by dialysis and for producing negatively stained grids of the resulting trials. Further automation via robotic handling of the EM grids, and semi-automated transmission electron microscopic imaging and evaluation of the trial grids is also possible. We, and others, have developed working prototypes for several of these tools and tested and evaluated them in a simple screen of 24 crystallization conditions. While further development of these tools is certainly required for a turn-key system, the goal of fully automated screening appears to be within reach. PMID:17977016

  1. Recent advances in automated protein design and its future challenges.

    PubMed

    Setiawan, Dani; Brender, Jeffrey; Zhang, Yang

    2018-04-25

    Protein function is determined by protein structure which is in turn determined by the corresponding protein sequence. If the rules that cause a protein to adopt a particular structure are understood, it should be possible to refine or even redefine the function of a protein by working backwards from the desired structure to the sequence. Automated protein design attempts to calculate the effects of mutations computationally with the goal of more radical or complex transformations than are accessible by experimental techniques. Areas covered: The authors give a brief overview of the recent methodological advances in computer-aided protein design, showing how methodological choices affect final design and how automated protein design can be used to address problems considered beyond traditional protein engineering, including the creation of novel protein scaffolds for drug development. Also, the authors address specifically the future challenges in the development of automated protein design. Expert opinion: Automated protein design holds potential as a protein engineering technique, particularly in cases where screening by combinatorial mutagenesis is problematic. Considering solubility and immunogenicity issues, automated protein design is initially more likely to make an impact as a research tool for exploring basic biology in drug discovery than in the design of protein biologics.

  2. Prehistoric floods on the Tennessee River—Assessing the use of stratigraphic records of past floods for improved flood-frequency analysis

    USGS Publications Warehouse

    Harden, Tessa M.; O'Connor, Jim E.

    2017-06-14

    Stratigraphic analysis, coupled with geochronologic techniques, indicates that a rich history of large Tennessee River floods is preserved in the Tennessee River Gorge area. Deposits of flood sediment from the 1867 peak discharge of record (460,000 cubic feet per second at Chattanooga, Tennessee) are preserved at many locations throughout the study area at sites with flood-sediment accumulation. Small exposures at two boulder overhangs reveal evidence of three to four other floods similar in size, or larger, than the 1867 flood in the last 3,000 years—one possibly as much or more than 50 percent larger. Records of floods also are preserved in stratigraphic sections at the mouth of the gorge at Williams Island and near Eaves Ferry, about 70 river miles upstream of the gorge. These stratigraphic records may extend as far back as about 9,000 years ago, giving a long history of Tennessee River floods. Although more evidence is needed to confirm these findings, a more in-depth comprehensive paleoflood study is feasible for the Tennessee River.

  3. Seismic stratigraphic architecture of the Disko Bay trough-mouth fan system, West Greenland

    NASA Astrophysics Data System (ADS)

    Hofmann, Julia C.; Knutz, Paul C.

    2015-04-01

    Spatial and temporal changes of the Greenland Ice Sheet on the continental shelf bordering Baffin Bay remain poorly constrained. Then as now, fast-flowing ice streams and outlet glaciers have played a key role for the mass balance and stability of polar ice sheets. Despite their significance for Greenland Ice Sheet dynamics and evolution, our understanding of their long-term behaviour is limited. The central West Greenland margin is characterized by a broad continental shelf where a series of troughs extend from fjords to the shelf margin, acting as focal points for trough-mouth fan (TMF) accummulations. The sea-ward bulging morphology and abrupt shelf-break of these major depositional systems is generated by prograding depocentres that formed during glacial maxima when ice streams reached the shelf edge, delivering large amounts of subglacial sediment onto the continental slope (Ó Cofaigh et al., 2013). The aim of this study is to unravel the seismic stratigraphic architecture and depositional processes of the Disko Bay TMF, aerially the largest single sedimentary system in West Greenland, using 2D and 3D seismic reflection data, seabed bathymetry and stratigraphic information from exploration well Hellefisk-1. The south-west Disko Bay is intersected by a deep, narrow trough, Egedesminde Dyb, which extends towards the southwest and links to the shallower and broader cross-shelf Disko Trough (maximum water depths of > 1000 m and a trough length of c. 370 km). Another trough-like depression (trough length of c. 120 km) in the northern part of the TMF, indicating a previous position of the ice stream, can be distinguished on the seabed topographic map and the seismic images. The Disko Bay TMF itself extends from the shelf edge down to the abyssal plain (abyssal floor depths of 2000 m) of the southern Baffin Bay. Based on seismic stratigraphic configurations relating to reflection terminations, erosive patterns and seismic facies (Mitchum et al., 1977), the TMF

  4. Mars Structural and Stratigraphic Mapping along the Coprates Rise

    NASA Technical Reports Server (NTRS)

    Saunders, R Stephen

    2009-01-01

    This geologic mapping project supports a topical study of structures in east Thaumasia associated with the Coprates rise. The study examines cuesta-like features on the east flank of the Coprates rise first identified by Saunders et al. [1]. Mapping combines detailed local stratigraphy, structural geology and topography. Hogbacks and cuestas indicate erosion of tilted rock units. The extent of the erosion will be determined in the course of the mapping. The region of interest lies along the eastern margin of Thaumasia bounded by latitudes -15 and -35 and longitudes 50 to 70 W (Figure 1). Three MTM geologic quadrangles are being compiled for publication by the USGS (-20057, -25057, -30057). All existing data sources are used including THEMIS, MOC, CTX, HiRISE, MOLA and gravity, as well as higher level data available through the PDS data nodes at ASU, UA and Washington University. The extremely valuable ASU JMARS tools are used for analysis of many of the data sets. ArcGIS software has been obtained and is being learned for the map compilation.

  5. Stratigraphic and palaeoenvironmental summary of the south-east Georgia embayment: a correlation of exploratory wells

    USGS Publications Warehouse

    Poppe, Lawrence J.; Popenoe, Peter; Poag, C. Wylie; Swift, B. Ann

    1995-01-01

    A Continental Offshore Stratigraphic Test (COST) well and six exploratory wells have been drilled in the south-east Georgia embayment. The oldest rocks penetrated are weakly metamorphosed Lower Ordovician quartz arenites and Silurian shales and argillites in the Transco 1005-1 well and Upper Devonian argillites in the COST GE-1 well. These marine strata, which are equivalent to the Tippecanoe sequence in Florida, underlie the post-rift unconformity and represent part of a disjunct fragment of Gondwana that was sutured to the North American craton during the late Palaeozoic Alleghanian orogeny. The Palaeozoic strata are unconformably overlain by interbedded non-marine Jurassic (Bajocian and younger) sandstones and shales and marginal marine Lower Cretaceous sandstones, calcareous shales and carbonates, which contain scattered beds of coal and evaporite. Together, these rocks are stratigraphically equivalent to the onshore Fort Pierce and Cotton Valley(?) Formations and rocks of the Lower Cretaceous Comanchean Provincial Series. The abundance of carbonates and evaporites in this interval, which reflects marine influences within the embayment, increases upwards, eastwards and southwards. The Upper Cretaceous part of the section is composed mainly of neritic calcareous shales and shaley limestones stratigraphically equivalent to the primarily marginal marine facies of the onshore Atkinson, Cape Fear and Middendorf Formations and Black Creek Group, and to limestones and shales of the Lawson Limestone and Peedee Formations. Cenozoic strata are primarily semiconsolidated marine carbonates. Palaeocene to middle Eocene strata are commonly cherty; middle Miocene to Pliocene strata are massive and locally phosphatic and glauconitic; Quaternary sediments are dominated by unconsolidated carbonate sands. The effects of eustatic changes and shifts in the palaeocirculation are recorded in the Upper Cretaceous and Tertiary strata.

  6. Morphodynamics and stratigraphic architecture of shelf-edge deltas subject to constant vs. dynamic environmental forcings

    NASA Astrophysics Data System (ADS)

    Straub, K. M.

    2017-12-01

    When deltas dock at the edge of continental margins they generally construct thick stratigraphic intervals and activate channelized continental slope systems. Deposits of shelf-edge deltas have the capacity to store detailed paleo-environmental records, given their location in the source to sink system. However, present day highstand sea-level conditions have pushed most deltaic systems well inbound of their shelf-edges, making it difficult to study their space-time dynamics and resulting stratigraphic products. Several competing theories describe how deltas and their downslope environments respond to sea-level cycles of varying magnitude and periodicity. We explore these hypotheses in a physical experiment where the topographic evolution of a coupled delta and downdip slope system was monitored at high temporal and spatial resolution. The experiment had three stages. In the first stage a delta aggraded at the shelf-edge under constant water and sediment supply, in addition to a constant generation of accommodation through a sea-level rise. In the second stage the sediment transport system responded to low magnitude and high frequency sea-level cycles. Finally, in the third stage the transport system responded to a high magnitude and long period sea-level cycle. In each stage, fine sediment from the input grain size distribution and dissolved salt in the input water supply promoted plunging hyperpycnal flows. Specifically, we compare the mean and temporal variability of the sediment delivered to the slope system between stages. In addition, we compare stratigraphic architecture and sediment sizes delivered to the slope system in each stage. These results are used to improve inversion of slope deposits for paleo-environmental forcings.

  7. Using Outcrop Exposures on the Road to Yellowknife Bay to Build a Stratigraphic Column, Gale Crater, Mars

    NASA Technical Reports Server (NTRS)

    Stack, K. M.; Grotzinger, J. P.; Sumner, D.; Ehlmann, B. L.; Milliken, R. E.; Eigenbrode, J. L.; Gupta, S.; Williams, R. M. E.; Kah, L. C.; Lewis, K. W.

    2013-01-01

    Since landing in Gale Crater on August 5, 2012, the Curiosity rover has driven 450 m east, descending approximately 15 m in elevation from the Bradbury landing site to Yellowknife Bay. Outcrop exposure along this drive has been discontinuous, but isolated outcrops may represent windows into underlying inplace stratigraphy. This study presents an inventory of outcrops targeted by Curiosity (Figs. 1-2), grouped by lithological properties observed in Mastcam and Navcam imagery. Outcrop locations are placed in a stratigraphic context using orbital imagery and first principles of stratigraphy. The stratigraphic models presented here represent an essential first step in understanding the relative age relationships of lithological units encountered at the Curiosity landing site. Such observations will provide crucial context for assessing habitability potential of ancient Gale crater environments and organic matter preservation.

  8. Automated structure and flow measurement - a promising tool in nailfold capillaroscopy.

    PubMed

    Berks, Michael; Dinsdale, Graham; Murray, Andrea; Moore, Tonia; Manning, Joanne; Taylor, Chris; Herrick, Ariane L

    2018-07-01

    Despite increasing interest in nailfold capillaroscopy, objective measures of capillary structure and blood flow have been little studied. We aimed to test the hypothesis that structural measurements, capillary flow, and a combined measure have the predictive power to separate patients with systemic sclerosis (SSc) from those with primary Raynaud's phenomenon (PRP) and healthy controls (HC). 50 patients with SSc, 12 with PRP, and 50 HC were imaged using a novel capillaroscopy system that generates high-quality nailfold images and provides fully-automated measurements of capillary structure and blood flow (capillary density, mean width, maximum width, shape score, derangement and mean flow velocity). Population statistics summarise the differences between the three groups. Areas under ROC curves (A Z ) were used to measure classification accuracy when assigning individuals to SSc and HC/PRP groups. Statistically significant differences in group means were found between patients with SSc and both HC and patients with PRP, for all measurements, e.g. mean width (μm) ± SE: 15.0 ± 0.71, 12.7 ± 0.74 and 11.8 ± 0.23 for SSc, PRP and HC respectively. Combining the five structural measurements gave better classification (A Z  = 0.919 ± 0.026) than the best single measurement (mean width, A Z  = 0.874 ± 0.043), whilst adding flow further improved classification (A Z  = 0.930 ± 0.024). Structural and blood flow measurements are both able to distinguish patients with SSc from those with PRP/HC. Importantly, these hold promise as clinical trial outcome measures for treatments aimed at improving finger blood flow or microvascular remodelling. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Automation, parallelism, and robotics for proteomics.

    PubMed

    Alterovitz, Gil; Liu, Jonathan; Chow, Jijun; Ramoni, Marco F

    2006-07-01

    The speed of the human genome project (Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C. et al., Nature 2001, 409, 860-921) was made possible, in part, by developments in automation of sequencing technologies. Before these technologies, sequencing was a laborious, expensive, and personnel-intensive task. Similarly, automation and robotics are changing the field of proteomics today. Proteomics is defined as the effort to understand and characterize proteins in the categories of structure, function and interaction (Englbrecht, C. C., Facius, A., Comb. Chem. High Throughput Screen. 2005, 8, 705-715). As such, this field nicely lends itself to automation technologies since these methods often require large economies of scale in order to achieve cost and time-saving benefits. This article describes some of the technologies and methods being applied in proteomics in order to facilitate automation within the field as well as in linking proteomics-based information with other related research areas.

  10. Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases.

    PubMed

    Dokarry, Melissa; Laurendon, Caroline; O'Maille, Paul E

    2012-01-01

    Structure-based combinatorial protein engineering (SCOPE) is a homology-independent recombination method to create multiple crossover gene libraries by assembling defined combinations of structural elements ranging from single mutations to domains of protein structure. SCOPE was originally inspired by DNA shuffling, which mimics recombination during meiosis, where mutations from parental genes are "shuffled" to create novel combinations in the resulting progeny. DNA shuffling utilizes sequence identity between parental genes to mediate template-switching events (the annealing and extension of one parental gene fragment on another) in PCR reassembly reactions to generate crossovers and hence recombination between parental genes. In light of the conservation of protein structure and degeneracy of sequence, SCOPE was developed to enable the "shuffling" of distantly related genes with no requirement for sequence identity. The central principle involves the use of oligonucleotides to encode for crossover regions to choreograph template-switching events during PCR assembly of gene fragments to create chimeric genes. This approach was initially developed to create libraries of hybrid DNA polymerases from distantly related parents, and later developed to create a combinatorial mutant library of sesquiterpene synthases to explore the catalytic landscapes underlying the functional divergence of related enzymes. This chapter presents a simplified protocol of SCOPE that can be integrated with different mutagenesis techniques and is suitable for automation by liquid-handling robots. Two examples are presented to illustrate the application of SCOPE to create gene libraries using plant sesquiterpene synthases as the model system. In the first example, we outline how to create an active-site library as a series of complex mixtures of diverse mutants. In the second example, we outline how to create a focused library as an array of individual clones to distil minimal combinations of

  11. Geodynamic Evolution of Northeastern Tunisia During the Maastrichtian-Paleocene Time: Insights from Integrated Seismic Stratigraphic Analysis

    NASA Astrophysics Data System (ADS)

    Abidi, Oussama; Inoubli, Mohamed Hédi; Sebei, Kawthar; Amiri, Adnen; Boussiga, Haifa; Nasr, Imen Hamdi; Salem, Abdelhamid Ben; Elabed, Mahmoud

    2017-05-01

    The Maastrichtian-Paleocene El Haria formation was studied and defined in Tunisia on the basis of outcrops and borehole data; few studies were interested in its three-dimensional extent. In this paper, the El Haria formation is reviewed in the context of a tectono-stratigraphic interval using an integrated seismic stratigraphic analysis based on borehole lithology logs, electrical well logging, well shots, vertical seismic profiles and post-stack surface data. Seismic analysis benefits from appropriate calibration with borehole data, conventional interpretation, velocity mapping, seismic attributes and post-stack model-based inversion. The applied methodology proved to be powerful for charactering the marly Maastrichtian-Paleocene interval of the El Haria formation. Migrated seismic sections together with borehole measurements are used to detail the three-dimensional changes in thickness, facies and depositional environment in the Cap Bon and Gulf of Hammamet regions during the Maastrichtian-Paleocene time. Furthermore, dating based on their microfossil content divulges local and multiple internal hiatuses within the El Haria formation which are related to the geodynamic evolution of the depositional floor since the Campanian stage. Interpreted seismic sections display concordance, unconformities, pinchouts, sedimentary gaps, incised valleys and syn-sedimentary normal faulting. Based on the seismic reflection geometry and terminations, seven sequences are delineated. These sequences are related to base-level changes as the combination of depositional floor paleo-topography, tectonic forces, subsidence and the developed accommodation space. These factors controlled the occurrence of the various parts of the Maastrichtian-Paleocene interval. Detailed examinations of these deposits together with the analysis of the structural deformation at different time periods allowed us to obtain a better understanding of the sediment architecture in depth and the delineation of

  12. Automated campaign system

    NASA Astrophysics Data System (ADS)

    Vondran, Gary; Chao, Hui; Lin, Xiaofan; Beyer, Dirk; Joshi, Parag; Atkins, Brian; Obrador, Pere

    2006-02-01

    To run a targeted campaign involves coordination and management across numerous organizations and complex process flows. Everything from market analytics on customer databases, acquiring content and images, composing the materials, meeting the sponsoring enterprise brand standards, driving through production and fulfillment, and evaluating results; all processes are currently performed by experienced highly trained staff. Presented is a developed solution that not only brings together technologies that automate each process, but also automates the entire flow so that a novice user could easily run a successful campaign from their desktop. This paper presents the technologies, structure, and process flows used to bring this system together. Highlighted will be how the complexity of running a targeted campaign is hidden from the user through technologies, all while providing the benefits of a professionally managed campaign.

  13. Improving the driver-automation interaction: an approach using automation uncertainty.

    PubMed

    Beller, Johannes; Heesen, Matthias; Vollrath, Mark

    2013-12-01

    The aim of this study was to evaluate whether communicating automation uncertainty improves the driver-automation interaction. A false system understanding of infallibility may provoke automation misuse and can lead to severe consequences in case of automation failure. The presentation of automation uncertainty may prevent this false system understanding and, as was shown by previous studies, may have numerous benefits. Few studies, however, have clearly shown the potential of communicating uncertainty information in driving. The current study fills this gap. We conducted a driving simulator experiment, varying the presented uncertainty information between participants (no uncertainty information vs. uncertainty information) and the automation reliability (high vs.low) within participants. Participants interacted with a highly automated driving system while engaging in secondary tasks and were required to cooperate with the automation to drive safely. Quantile regressions and multilevel modeling showed that the presentation of uncertainty information increases the time to collision in the case of automation failure. Furthermore, the data indicated improved situation awareness and better knowledge of fallibility for the experimental group. Consequently, the automation with the uncertainty symbol received higher trust ratings and increased acceptance. The presentation of automation uncertaintythrough a symbol improves overall driver-automation cooperation. Most automated systems in driving could benefit from displaying reliability information. This display might improve the acceptance of fallible systems and further enhances driver-automation cooperation.

  14. Automated torso organ segmentation from 3D CT images using structured perceptron and dual decomposition

    NASA Astrophysics Data System (ADS)

    Nimura, Yukitaka; Hayashi, Yuichiro; Kitasaka, Takayuki; Mori, Kensaku

    2015-03-01

    This paper presents a method for torso organ segmentation from abdominal CT images using structured perceptron and dual decomposition. A lot of methods have been proposed to enable automated extraction of organ regions from volumetric medical images. However, it is necessary to adjust empirical parameters of them to obtain precise organ regions. This paper proposes an organ segmentation method using structured output learning. Our method utilizes a graphical model and binary features which represent the relationship between voxel intensities and organ labels. Also we optimize the weights of the graphical model by structured perceptron and estimate the best organ label for a given image by dynamic programming and dual decomposition. The experimental result revealed that the proposed method can extract organ regions automatically using structured output learning. The error of organ label estimation was 4.4%. The DICE coefficients of left lung, right lung, heart, liver, spleen, pancreas, left kidney, right kidney, and gallbladder were 0.91, 0.95, 0.77, 0.81, 0.74, 0.08, 0.83, 0.84, and 0.03, respectively.

  15. The stratigraphic utility of the trace fossil Pteridichnites biseriatus in the Upper Devonian of eastern West Virginia and western Virginia, USA

    USGS Publications Warehouse

    McDowell, R.R.; Avary, K.L.; Matchen, D.L.; Britton, J.Q.

    2007-01-01

    Similar lithologies and lithofacies are present in two Upper Devonian siliciclastic units, the Brallier and Foreknobs formations, in eastern West Virginia and western Virginia, USA. Specimens of an unusual trace fossil, Pteridichnites biseriatus, occur in variable numbers throughout both stratigraphic units. P. biseriatus is present in abundance in the lowermost Brallier and this abundance-zone serves as a local stratigraphic marker for the Brallier. The trace fossil, originally suggested as an indication of polychaete or arthropod locomotion, is herein proposed as the locomotion trace of an unidentified ophiuroid.

  16. Automated Generation of Finite-Element Meshes for Aircraft Conceptual Design

    NASA Technical Reports Server (NTRS)

    Li, Wu; Robinson, Jay

    2016-01-01

    This paper presents a novel approach for automated generation of fully connected finite-element meshes for all internal structural components and skins of a given wing-body geometry model, controlled by a few conceptual-level structural layout parameters. Internal structural components include spars, ribs, frames, and bulkheads. Structural layout parameters include spar/rib locations in wing chordwise/spanwise direction and frame/bulkhead locations in longitudinal direction. A simple shell thickness optimization problem with two load conditions is used to verify versatility and robustness of the automated meshing process. The automation process is implemented in ModelCenter starting from an OpenVSP geometry and ending with a NASTRAN 200 solution. One subsonic configuration and one supersonic configuration are used for numerical verification. Two different structural layouts are constructed for each configuration and five finite-element meshes of different sizes are generated for each layout. The paper includes various comparisons of solutions of 20 thickness optimization problems, as well as discussions on how the optimal solutions are affected by the stress constraint bound and the initial guess of design variables.

  17. An automated parallel crystallisation search for predicted crystal structures and packing motifs of carbamazepine.

    PubMed

    Florence, Alastair J; Johnston, Andrea; Price, Sarah L; Nowell, Harriott; Kennedy, Alan R; Shankland, Norman

    2006-09-01

    An automated parallel crystallisation search for physical forms of carbamazepine, covering 66 solvents and five crystallisation protocols, identified three anhydrous polymorphs (forms I-III), one hydrate and eight organic solvates, including the single-crystal structures of three previously unreported solvates (N,N-dimethylformamide (1:1); hemi-furfural; hemi-1,4-dioxane). Correlation of physical form outcome with the crystallisation conditions demonstrated that the solvent adopts a relatively nonspecific role in determining which polymorph is obtained, and that the previously reported effect of a polymer template facilitating the formation of form IV could not be reproduced by solvent crystallisation alone. In the accompanying computational search, approximately half of the energetically feasible predicted crystal structures exhibit the C=O...H--N R2(2)(8)dimer motif that is observed in the known polymorphs, with the most stable correctly corresponding to form III. Most of the other energetically feasible structures, including the global minimum, have a C=O...H--N C(4) chain hydrogen bond motif. No such chain structures were observed in this or any other previously published work, suggesting that kinetic, rather than thermodynamic, factors determine which of the energetically feasible crystal structures are observed experimentally, with the kinetics apparently favouring nucleation of crystal structures based on the CBZ-CBZ R2(2)(8) motif. (c) 2006 Wiley-Liss, Inc. and the American Pharmacists Association.

  18. The historical development and basis of human factors guidelines for automated systems in aeronautical operations

    NASA Technical Reports Server (NTRS)

    Ciciora, J. A.; Leonard, S. D.; Johnson, N.; Amell, J.

    1984-01-01

    In order to derive general design guidelines for automated systems a study was conducted on the utilization and acceptance of existing automated systems as currently employed in several commercial fields. Four principal study area were investigated by means of structured interviews, and in some cases questionnaires. The study areas were aviation, a both scheduled airline and general commercial aviation; process control and factory applications; office automation; and automation in the power industry. The results of over eighty structured interviews were analyzed and responses categoried as various human factors issues for use by both designers and users of automated equipment. These guidelines address such items as general physical features of automated equipment; personnel orientation, acceptance, and training; and both personnel and system reliability.

  19. The Lower Silurian Osmundsberg K-bentonite. Part I: Stratigraphic position, distribution, and palaeogeographic significance

    USGS Publications Warehouse

    Bergstrom, Stig M.; Huff, W.D.; Kolata, Dennis R.

    1998-01-01

    A large number of Lower Silurian (Llandovery) K-bentonite beds have been recorded from northwestern Europe, particularly in Baltoscandia and the British Isles, but previous attempts to trace single beds regionally have yielded inconclusive results. The present study suggests that based on its unusual thickness, stratigraphic position and trace element geochemistry, one Telychian ash bed, the Osmundsberg K-bentonite, can be recognized at many localities in Estonia, Sweden and Norway and probably also in Scotland and Northern Ireland. This bed, which is up to 115 cm thick, is in the lower-middle turriculatus Zone. The stratigraphic position, thickness variation and geographic distribution of the Osmundsberg K-bentonite are illustrated by means of 12 selected Llandovery successions in Sweden, Estonia, Norway, Denmark, Scotland and Northern Ireland. In Baltoscandia, the Osmundsberg K-bentonite shows a trend of general thickness increase in a western direction suggesting that its source area was located in the northern Iapetus region between Baltica and Laurentia. Because large-magnitude ash falls like the one that produced the Osmundsberg K-bentonite last at most a few weeks, such an ash bed may be used as a unique time-plane for a variety of regional geological and palaeontological studies.

  20. Exploring the Middle Pleistocene Lake Suguta Sr-isotope Stratigraphic record

    NASA Astrophysics Data System (ADS)

    Vonhof, Hubert; Junginger, Annett; Agmon, Nadav; Trauth, Martin

    2017-04-01

    Several studies into the Quaternary stratigraphic record of the Sr-isotope composition of paleolake Turkana in the East African Rift System (EARS) show how variation of climate left a signal of changing lacustrine Sr isotope values. This Sr isotope signal was captured in the lacustrine fossil record of the Turkana Basin, and can be a useful chemostratigraphic tool (e.g. Joordens et al., 2011; van der Lubbe et al., submitted). Such lacustrine Sr-isotope changes are believed to be paced by orbital-forced insolation cyclicity, and interpreted to be the result of changing contribution of run-off from different sub-catchments of lake Turkana, as climate change shifted regional rainfall patterns. Here, we present a first set of data from a middle Pleistocene stratigraphical sequence in the Suguta Valley, South of the Turkana Basin in the EARS. This sequence spans a couple of sedimentological cycles that potentially represent precession-forced lake level variation. In this setting, the Sr-isotope data do not vary in phase with these sedimentological cycles, but demonstrate a long trend of Sr isotope change. This may suggest that the catchment configuration of the Suguta Valley in the Mid Pleistocene was less suitable to record precession-forced hydroclimate change in Lacustrine Sr isotope ratios. This may have implications for the Turkana Basin Sr isotope record as well, because the two basins are believed to have been hydrologically connected in the Middle Pleistocene. references: 1)Joordens, J.C.A. et al., 2011. An astronomically-tuned climate framework for hominins in the Turkana Basin. Earth and Planetary Science Letters 307, 1-8. 2)van der Lubbe et al., submitted. Gradual or abrupt? Changes in water source of Lake Turkana (Kenya) during the African Humid Period inferred from Sr isotope ratios

  1. Investigation of stratigraphic mapping in paintings using micro-Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Karagiannis, Georgios Th.; Apostolidis, Georgios K.

    2016-04-01

    In this work, microRaman spectroscopy is used to investigate the stratigraphic mapping in paintings. The objective of mapping imaging is to segment the dataset, here spectra, into clusters each of which consisting spectra that have similar characteristics; hence, similar chemical composition. The spatial distribution of such clusters can be illustrated in pseudocolor images, in which each pixel of image is colored according to its cluster membership. Such mapping images convey information about the spatial distribution of the chemical substances in an object. Moreover, the laser light source that is used has excitation in 1064 nm, i.e., near infrared (NIR), allowing the penetration of the radiation in deeper layers. Thus, the mapping images that are produced by clustering the acquired spectra (specifying specific bands of Raman shifts) can provide stratigraphic information in the mapping images, i.e., images that convey information of the distribution of substances from deeper, as well. To cluster the spectra, unsupervised machine learning algorithms are applied, e.g., hierarchical clustering. Furthermore, the optical microscopy camera (×50), where the Raman probe (B and WTek iRaman EX) is plugged in, is attached to a computerized numerical control (CNC) system which is driven by a software that is specially developed for Raman mapping. This software except for the conventional CNC operation allows the user to parameterize the spectrometer and check each and every measurement to ensure proper acquisition. This facility is important in painting investigation because some materials are vulnerable to such specific parameterization that other materials demand. The technique is tested on a portable experimental overpainted icon of a known stratigraphy. Specifically, the under icon, i.e., the wavy hair of "Saint James", can be separated from upper icon, i.e., the halo of Mother of God in the "Descent of the Cross".

  2. The role of sediment supply in large-scale stratigraphic architecture of ancient Gilbert-type deltas (Pliocene Siena-Radicofani Basin, Italy)

    NASA Astrophysics Data System (ADS)

    Martini, Ivan; Ambrosetti, Elisa; Sandrelli, Fabio

    2017-04-01

    Aggradation, progradation and retrogradation are the main patterns that define the large-scale architecture of Gilbert-type deltas. These patterns are governed by the ratio between the variation in accommodation space and sediment supply experienced during delta growth. Sediment supply variations are difficult to estimate in ancient settings; hence, it is rarely possible to assess its significance in the large-scale stratigraphic architecture of Gilbert-type deltas. This paper presents a stratigraphic analysis of a Pliocene deltaic complex composed of two coeval and narrowly spaced deltaic branches. The two branches recorded the same tectonic- and climate-induced accommodation space variations. As a result, this deltaic complex represents a natural laboratory for testing the effects of sediment supply variations on the stratigraphic architecture of Gilbert-type deltas. The field data suggest that a sediment supply which is able to counteract the accommodation generated over time promotes the aggradational/progradational attitude of Gilbert-type deltas, as well as the development of thick foreset deposits. By contrast, if the sediment supply is not sufficient for counterbalancing the generated accommodation, an aggradational/retrogradational stratigraphic architecture is promoted. In this case, the deltaic system is forced to withdraw during the different phases of generation of accommodation, with the subsequent flooding of previously deposited sub-horizontal topset deposits (i.e., the delta plain). The subsequent deltaic progradation occurs above these deposits and, consequently, the available space for foresets growth is limited to the water depth between the base-level and the older delta plain. This leads to the vertical stacking of relatively thin deltaic deposits with an overall aggradatational/retrogradational attitude.

  3. PASS2: an automated database of protein alignments organised as structural superfamilies.

    PubMed

    Bhaduri, Anirban; Pugalenthi, Ganesan; Sowdhamini, Ramanathan

    2004-04-02

    The functional selection and three-dimensional structural constraints of proteins in nature often relates to the retention of significant sequence similarity between proteins of similar fold and function despite poor sequence identity. Organization of structure-based sequence alignments for distantly related proteins, provides a map of the conserved and critical regions of the protein universe that is useful for the analysis of folding principles, for the evolutionary unification of protein families and for maximizing the information return from experimental structure determination. The Protein Alignment organised as Structural Superfamily (PASS2) database represents continuously updated, structural alignments for evolutionary related, sequentially distant proteins. An automated and updated version of PASS2 is, in direct correspondence with SCOP 1.63, consisting of sequences having identity below 40% among themselves. Protein domains have been grouped into 628 multi-member superfamilies and 566 single member superfamilies. Structure-based sequence alignments for the superfamilies have been obtained using COMPARER, while initial equivalencies have been derived from a preliminary superposition using LSQMAN or STAMP 4.0. The final sequence alignments have been annotated for structural features using JOY4.0. The database is supplemented with sequence relatives belonging to different genomes, conserved spatially interacting and structural motifs, probabilistic hidden markov models of superfamilies based on the alignments and useful links to other databases. Probabilistic models and sensitive position specific profiles obtained from reliable superfamily alignments aid annotation of remote homologues and are useful tools in structural and functional genomics. PASS2 presents the phylogeny of its members both based on sequence and structural dissimilarities. Clustering of members allows us to understand diversification of the family members. The search engine has been

  4. Cockpit automation

    NASA Technical Reports Server (NTRS)

    Wiener, Earl L.

    1988-01-01

    The aims and methods of aircraft cockpit automation are reviewed from a human-factors perspective. Consideration is given to the mixed pilot reception of increased automation, government concern with the safety and reliability of highly automated aircraft, the formal definition of automation, and the ground-proximity warning system and accidents involving controlled flight into terrain. The factors motivating automation include technology availability; safety; economy, reliability, and maintenance; workload reduction and two-pilot certification; more accurate maneuvering and navigation; display flexibility; economy of cockpit space; and military requirements.

  5. Badenian (Middle Miocene) echinoids and starfish from western Ukraine, and their biogeographic and stratigraphic significance

    NASA Astrophysics Data System (ADS)

    Radwański, Andrzej; Górka, Marcin; Wysocka, Anna

    2014-06-01

    Echinoderms from the Badenian (Middle Miocene) of the Fore-Carpathian Basin of western Ukraine are facies restricted. The Mykolaiv Beds, stratigraphically older, yielded the starfish Astropecten forbesi (complete skeletons), two genera of sand dollars (Parascutella, Parmulechinus), and numerous other echinoids of the genera Psammechinus , Echinocyamus, Spatangus, Hemipatagus, Echinocardium, Clypeaster, Echinolampas, and Conolampas. The stratigraphically younger, calcareous Ternopil Beds yielded Eucidaris (complete coronae, isolated spines), Arbacina , Brissus, and Rhabdobrissus. Sixteen species of echinoids are distinguished and/or commented. A new brissid, Rhabdobrissus tarnopolensis sp. nov., is established. A mass occurrence of some species (Psammechinus dubius and Hemipatagus ocellatus) contrasts with that of mass aggregations (sand dollars and Echinocardium leopolitanum) by dynamic events in selected layers of proximal tempestites. Of special note is the occurrence of very small specimens, interpreted as juveniles (`babies') having been swept out of their restricted biotopes (`nurseries'). Some species hitherto regarded as of Early Miocene age, and the problem of their persistence beyond the Fore-Carpathian Basin and/or migration into that basin during the Middle Miocene transgression are discussed.

  6. [Automated morphometric evaluation of the chromatin structure of liver cell nuclei after vagotomy].

    PubMed

    Butusova, N N; Zhukotskiĭ, A V; Sherbo, I V; Gribkov, E N; Dubovaia, T K

    1989-05-01

    The morphometric analysis of the interphase chromatine structure of the hepatic cells nuclei was carried out on the automated TV installation for the quantitative analysis of images "IBAS-2" (by the OPTON firm, the FRG) according to 50 optical and geometric parameters during various periods (1.2 and 4 weeks) after the vagotomy operation. It is determined that upper-molecular organisation of chromatine undergoes the biggest changes one week after operation, and changes of granular component are more informative than changes of the nongranular component (with the difference 15-20%). It was also revealed that chromatine components differ in tinctorial properties, which are evidently dependent on physicochemical characteristics of the chromatine under various functional conditions of the cell. As a result of the correlation analysis the group of morphometric indices of chromatine structure was revealed, which are highly correlated with level of transcription activity of chromatine during various terms after denervation. The correlation quotient of these parameters is 0.85-0.97. The summing up: vagus denervation of the liver causes changes in the morphofunctional organisation of the chromatine.

  7. Automated software system for checking the structure and format of ACM SIG documents

    NASA Astrophysics Data System (ADS)

    Mirza, Arsalan Rahman; Sah, Melike

    2017-04-01

    Microsoft (MS) Office Word is one of the most commonly used software tools for creating documents. MS Word 2007 and above uses XML to represent the structure of MS Word documents. Metadata about the documents are automatically created using Office Open XML (OOXML) syntax. We develop a new framework, which is called ADFCS (Automated Document Format Checking System) that takes the advantage of the OOXML metadata, in order to extract semantic information from MS Office Word documents. In particular, we develop a new ontology for Association for Computing Machinery (ACM) Special Interested Group (SIG) documents for representing the structure and format of these documents by using OWL (Web Ontology Language). Then, the metadata is extracted automatically in RDF (Resource Description Framework) according to this ontology using the developed software. Finally, we generate extensive rules in order to infer whether the documents are formatted according to ACM SIG standards. This paper, introduces ACM SIG ontology, metadata extraction process, inference engine, ADFCS online user interface, system evaluation and user study evaluations.

  8. Bed II Sequence Stratigraphic context of EF-HR and HWK EE archaeological sites, and the Oldowan/Acheulean succession at Olduvai Gorge, Tanzania.

    PubMed

    Stanistreet, Ian G; McHenry, Lindsay J; Stollhofen, Harald; de la Torre, Ignacio

    2018-04-20

    Archaeological excavations at EF-HR and HWK EE allow reassessment of Bed II stratigraphy within the Junction Area and eastern Olduvai Gorge. Application of Sequence Stratigraphic methods provides a time-stratigraphic framework enabling correlation of sedimentary units across facies boundaries, applicable even in those areas where conventional timelines, such as tephrostratigraphic markers, are absent, eroded, or reworked. Sequence Stratigraphically, Bed II subdivides into five major Sequences 1 to 5, all floored by major disconformities that incise deeply into the underlying succession, proving that simple "layer cake" stratigraphy is inappropriate. Previous establishment of the Lemuta Member has invalidated the use of Tuff IIA as the boundary between Lower and Middle Bed II, now redefined at the disconformity between Sequences 2 and 3, a lithostratigraphic contact underlying the succession containing the Lower, Middle, and Upper Augitic Sandstones. HWK EE site records Oldowan technology in the Lower Augitic Sandstone at the base of Sequence 3, within Middle Bed II. We suggest placement of recently reported Acheulean levels at FLK W within the Middle Augitic Sandstone, thus emphasizing that handaxes are yet to be found in earlier stratigraphic units of the Olduvai sequence. This would place a boundary between the Oldowan and Acheulean technologies at Olduvai in the Tuff IIB zone or earliest Middle Augitic Sandstone. A major disconformity between Sequences 3 and 4 at and near EF-HR cuts through the level of Tuff IIC, placing the main Acheulean EF-HR assemblage at the base of Sequence 4, within Upper rather than Middle Bed II. Sequence stratigraphic methods also yield a more highly resolved Bed II stratigraphic framework. Backwall and sidewall surveying of archaeological trenches at EF-HR and HWK EE permits definition of "Lake-parasequences" nested within the major Sequences that record downcutting of disconformities associated with lake regression, then

  9. About development of automation control systems

    NASA Astrophysics Data System (ADS)

    Myshlyaev, L. P.; Wenger, K. G.; Ivushkin, K. A.; Makarov, V. N.

    2018-05-01

    The shortcomings of approaches to the development of modern control automation systems and ways of their improvement are given: the correct formation of objects for study and optimization; a joint synthesis of control objects and control systems, an increase in the structural diversity of the elements of control systems. Diagrams of control systems with purposefully variable structure of their elements are presented. Structures of control algorithms for an object with a purposefully variable structure are given.

  10. Architecture Views Illustrating the Service Automation Aspect of SOA

    NASA Astrophysics Data System (ADS)

    Gu, Qing; Cuadrado, Félix; Lago, Patricia; Duenãs, Juan C.

    Earlier in this book, Chapter 8 provided a detailed analysis of service engineering, including a review of service engineering techniques and methodologies. This chapter is closely related to Chapter 8 as shows how such approaches can be used to develop a service, with particular emphasis on the identification of three views (the automation decision view, degree of service automation view and service automation related data view) that structure and ease elicitation and documentation of stakeholders' concerns. This is carried out through two large case studies to learn the industrial needs in illustrating services deployment and configuration automation. This set of views adds to the more traditional notations like UML, the visual power of attracting the attention of their users to the addressed concerns, and assist them in their work. This is especially crucial in service oriented architecting where service automation is highly demanded.

  11. Automated identification of RNA 3D modules with discriminative power in RNA structural alignments.

    PubMed

    Theis, Corinna; Höner Zu Siederdissen, Christian; Hofacker, Ivo L; Gorodkin, Jan

    2013-12-01

    Recent progress in predicting RNA structure is moving towards filling the 'gap' in 2D RNA structure prediction where, for example, predicted internal loops often form non-canonical base pairs. This is increasingly recognized with the steady increase of known RNA 3D modules. There is a general interest in matching structural modules known from one molecule to other molecules for which the 3D structure is not known yet. We have created a pipeline, metaRNAmodules, which completely automates extracting putative modules from the FR3D database and mapping of such modules to Rfam alignments to obtain comparative evidence. Subsequently, the modules, initially represented by a graph, are turned into models for the RMDetect program, which allows to test their discriminative power using real and randomized Rfam alignments. An initial extraction of 22 495 3D modules in all PDB files results in 977 internal loop and 17 hairpin modules with clear discriminatory power. Many of these modules describe only minor variants of each other. Indeed, mapping of the modules onto Rfam families results in 35 unique locations in 11 different families. The metaRNAmodules pipeline source for the internal loop modules is available at http://rth.dk/resources/mrm.

  12. Facies analysis, palaeoenvironmental reconstruction and stratigraphic development of the Early Cretaceous sediments (Lower Bima Member) in the Yola Sub-basin, Northern Benue Trough, NE Nigeria

    NASA Astrophysics Data System (ADS)

    Sarki Yandoka, Babangida M.; Abubakar, M. B.; Abdullah, Wan Hasiah; Amir Hassan, M. H.; Adamu, Bappah U.; Jitong, John S.; Aliyu, Abdulkarim H.; Adegoke, Adebanji Kayode

    2014-08-01

    The Benue Trough of Nigeria is a major rift basin formed from the tension generated by the separation of African and South American plates in the Early Cretaceous. It is geographically sub-divided into Southern, Central and Northern Benue portions. The Northern Benue Trough comprises two sub-basins; the N-S trending Gongola Sub-basin and the E-W trending Yola Sub-basin. The Bima Formation is the oldest lithogenetic unit occupying the base of the Cretaceous successions in the Northern Benue Trough. It is differentiated into three members; the Lower Bima (B1), the Middle Bima (B2) and the Upper Bima (B3). Facies and their stratigraphical distribution analyses were conducted on the Lower Bima Member exposed mainly at the core of the NE-SW axially trending Lamurde Anticline in the Yola Sub-basin, with an objective to interpret the paleodepositional environments, and to reconstruct the depositional model and the stratigraphical architecture. Ten (10) lithofacies were identified on the basis of lithology, grain size, sedimentary structures and paleocurrent analysis. The facies constitute three (3) major facies associations; the gravelly dominated, the sandy dominated and the fine grain dominated. These facies and facies associations were interpreted and three facies successions were recognized; the alluvial-proximal braided river, the braided river and the lacustrine-marginal lacustrine. The stratigraphic architecture indicates a rifted (?pull-apart) origin as the facies distribution shows a progradational succession from a shallow lacustrine/marginal lacustrine (at the axial part of the basin) to alluvial fan (sediment gravity flow)-proximal braided river (gravel bed braided river) and braided river (channel and overbank) depositional systems. The facies stacking patterns depict sedimentation mainly controlled by allogenic factors of climate and tectonism.

  13. Automation and Robotics for Space-Based Systems, 1991

    NASA Technical Reports Server (NTRS)

    Williams, Robert L., II (Editor)

    1992-01-01

    The purpose of this in-house workshop was to assess the state-of-the-art of automation and robotics for space operations from an LaRC perspective and to identify areas of opportunity for future research. Over half of the presentations came from the Automation Technology Branch, covering telerobotic control, extravehicular activity (EVA) and intra-vehicular activity (IVA) robotics, hand controllers for teleoperation, sensors, neural networks, and automated structural assembly, all applied to space missions. Other talks covered the Remote Manipulator System (RMS) active damping augmentation, space crane work, modeling, simulation, and control of large, flexible space manipulators, and virtual passive controller designs for space robots.

  14. Stratigraphic Stacking of Deepmarine Channel Levee Turbidites: Scales of Cyclicity and their Origin. Examples from the Laingsburg Fm. (Karoo, South Africa) and the Rosario Fm. (Baja, Mexico)

    NASA Astrophysics Data System (ADS)

    Kane, I. A.; Hodgson, D.

    2009-12-01

    Thinning upwards of the turbidite beds that form deepmarine channel levees is a common motif reported from modern and recent levees on the seafloor, from subsurface examples, and from outcropping ancient examples. Because levees are thought to be built by deposition from turbidity currents superelevated over their channel form, the volume and style of overbank deposition are controlled primarily by the relationship between levee height (i.e., thalweg to crest) and flow thickness, determining the amount of overspill. Thus stratigraphic variability of turbidite thickness is explained by some change in either or both of those factors, which may arise autocyclicly or allocyclicly. Variation in the ratio of intra-channel and extra-channel deposition can be an autocyclic stratigraphic response, e.g., in bypass dominated systems, thalweg aggradation may be retarded with respect to levee aggradation, hence as levee relief increases, flows become more confined and, given a relatively narrow range of flow sizes, the volume of overbank flow and deposit thickness decrease with stratigraphic height. However, the same stratigraphic response of the levee may occur due to allocyclic flow magnitude variation, i.e., through decreasing flow magnitude. In both the autocyclic and allocyclic case the stratigraphic response of the levee may be one of thinning upwards, even if the overall system response may be one of progradation (autocyclic bypassing case) or retrogradation (allocyclic decreasing flow magnitude case), with entirely different connotations for sequence stratigraphic interpretation. Here we report examples of different scales of bed thickness cyclicity (both thickening and thinning upward cycles superimposed by smaller scale cycles) within levees of the Rosario Formation, Baja California, Mexico, and from the Laingsburg Formation, Karoo, South Africa, and, together with published examples, discuss criteria for the recognition, and drivers of, autocyclic and allocyclic bed

  15. Vibration based structural health monitoring of an arch bridge: From automated OMA to damage detection

    NASA Astrophysics Data System (ADS)

    Magalhães, F.; Cunha, A.; Caetano, E.

    2012-04-01

    In order to evaluate the usefulness of approaches based on modal parameters tracking for structural health monitoring of bridges, in September of 2007, a dynamic monitoring system was installed in a concrete arch bridge at the city of Porto, in Portugal. The implementation of algorithms to perform the continuous on-line identification of modal parameters based on structural responses to ambient excitation (automated Operational Modal Analysis) has permitted to create a very complete database with the time evolution of the bridge modal characteristics during more than 2 years. This paper describes the strategy that was followed to minimize the effects of environmental and operational factors on the bridge natural frequencies, enabling, in a subsequent stage, the identification of structural anomalies. Alternative static and dynamic regression models are tested and complemented by a Principal Components Analysis. Afterwards, the identification of damages is tried with control charts. At the end, it is demonstrated that the adopted processing methodology permits the detection of realistic damage scenarios, associated with frequency shifts around 0.2%, which were simulated with a numerical model.

  16. Autonomy and Automation

    NASA Technical Reports Server (NTRS)

    Shively, Jay

    2017-01-01

    A significant level of debate and confusion has surrounded the meaning of the terms autonomy and automation. Automation is a multi-dimensional concept, and we propose that Remotely Piloted Aircraft Systems (RPAS) automation should be described with reference to the specific system and task that has been automated, the context in which the automation functions, and other relevant dimensions. In this paper, we present definitions of automation, pilot in the loop, pilot on the loop and pilot out of the loop. We further propose that in future, the International Civil Aviation Organization (ICAO) RPAS Panel avoids the use of the terms autonomy and autonomous when referring to automated systems on board RPA. Work Group 7 proposes to develop, in consultation with other workgroups, a taxonomy of Levels of Automation for RPAS.

  17. Evaluation of software tools for automated identification of neuroanatomical structures in quantitative β-amyloid PET imaging to diagnose Alzheimer's disease.

    PubMed

    Tuszynski, Tobias; Rullmann, Michael; Luthardt, Julia; Butzke, Daniel; Tiepolt, Solveig; Gertz, Hermann-Josef; Hesse, Swen; Seese, Anita; Lobsien, Donald; Sabri, Osama; Barthel, Henryk

    2016-06-01

    For regional quantification of nuclear brain imaging data, defining volumes of interest (VOIs) by hand is still the gold standard. As this procedure is time-consuming and operator-dependent, a variety of software tools for automated identification of neuroanatomical structures were developed. As the quality and performance of those tools are poorly investigated so far in analyzing amyloid PET data, we compared in this project four algorithms for automated VOI definition (HERMES Brass, two PMOD approaches, and FreeSurfer) against the conventional method. We systematically analyzed florbetaben brain PET and MRI data of ten patients with probable Alzheimer's dementia (AD) and ten age-matched healthy controls (HCs) collected in a previous clinical study. VOIs were manually defined on the data as well as through the four automated workflows. Standardized uptake value ratios (SUVRs) with the cerebellar cortex as a reference region were obtained for each VOI. SUVR comparisons between ADs and HCs were carried out using Mann-Whitney-U tests, and effect sizes (Cohen's d) were calculated. SUVRs of automatically generated VOIs were correlated with SUVRs of conventionally derived VOIs (Pearson's tests). The composite neocortex SUVRs obtained by manually defined VOIs were significantly higher for ADs vs. HCs (p=0.010, d=1.53). This was also the case for the four tested automated approaches which achieved effect sizes of d=1.38 to d=1.62. SUVRs of automatically generated VOIs correlated significantly with those of the hand-drawn VOIs in a number of brain regions, with regional differences in the degree of these correlations. Best overall correlation was observed in the lateral temporal VOI for all tested software tools (r=0.82 to r=0.95, p<0.001). Automated VOI definition by the software tools tested has a great potential to substitute for the current standard procedure to manually define VOIs in β-amyloid PET data analysis.

  18. Stratigraphic test well, Nantucket Island, Massachusetts

    USGS Publications Warehouse

    Folger, David W.; Hathaway, J.C.; Christopher, R.A.; Valentine, P.C.; Poag, C.W.

    1978-01-01

    The U.S. Geological Survey, in cooperation with the Massachusetts Water Resources Commission and the Nantucket Conservation Foundation, continuously cored 514 m of sediment and volcanic rock in a stratigraphic and water-quality test near the geographic center of Nantucket Island. Stratified sediments were divided texturally into three zones: the upper zone (0-128 m) contains mostly coarse sand and gravel; the middle zone (128-349 m) contains mostly silty clay and a few beds of sand and silt; and the lower zone (349-457 m) contains soft, unconsolidated, clayey sand. Below the lower zone, a saprolite, composed mostly of clay, grades abruptly downward at 470 m into partially altered basalt that extends to the bottom of the hole at 514 m. Calculations based on the Ghyben-Herzberg principle predicted a zone of freshwater 120-150 m thick. This principle is the theory of hydrostatic equilibrium between freshwater and more dense seawater in a coastal aquifer; it states that for each meter of ground-water elevation above sea level, the freshwater lens will depress the saltwater interface about 40 m below sea level. Freshwater or low-salinity brackish water was found in sediments far below the depth predicted by the Ghyben-Herzberg principle. These interstitial waters are probably relict ground water emplaced during times of low sea level during the Pleistocene. (Woodard-USGS)

  19. Stratigraphic framework and distribution of lignite on Crowleys Ridge, Arkansas

    USGS Publications Warehouse

    Meissner, Charles R.

    1983-01-01

    The purpose of this report is to establish a stratigraphic framework of lignite beds and associated strata of Crowleys Ridge, Arkansas. Drill hole data provided by the Arkansas Geological Commission is used in the synthesis and interpretation. Areas containing lignite of potential resource value are also delineated. To illustrate the regional stratigraphic framework of Crowleys Ridge, a cross section was constructed from logs of selected oil and gas test wells, along or adjacent to the north-south trending ridge over a distance of about 115 miles. This section reveals that lignite-bearing Tertiary formations dip gently southward along the ridge. The Paleocene-Eocene Wilcox Group forms the bedrock in the northern part of the ridge and successively younger bedrock of the Eocene Claiborne and Jackson Groups is identified in the central and southern part of the ridge. Crowleys Ridge is mantled with alluvium and loess of Quaternary age, and sand and gravel beds of the Lafayette Formation of Pliocene (?) age that unconformably overlie the Paleocene and Eocene rocks. The thickness of lignite-bearing sedimentary deposits ranges from 830 feet in the north to 2,480 feet in the south. The Wilcox, Claiborne, and Jackson Groups of Paleocene and Eocene age are believed to be fluvial-deltaic in origin. The detailed vertical and horizontal stratigraphic characteristics and distribution of lignite beds in the sediments were determined by constructing seven cross sections from lithologic and geophysical logs of the lignite investigations on Crowleys Ridge by the Arkansas Geological Commission and private companies. Correlation and interpretation of the lignite-bearing strata reveal ten lignite beds of resource potential. These lignite beds range from a few inches to 9.5 ft in thickness and are assigned to stratigraphic intervals that are designated as zone 1 through 7. Zone 1 is near the middle of the Wilcox Group and zone 7 is near the middle of the overlying Claiborne Group. Some

  20. Revised Subsurface Stratigraphic Framework of the Fort Union and Wasatch Formations, Powder River Basin, Wyoming and Montana

    USGS Publications Warehouse

    Flores, Romeo M.; Spear, Brianne D.; Purchase, Peter A.; Gallagher, Craig M.

    2010-01-01

    Described in this report is an updated subsurface stratigraphic framework of the Paleocene Fort Union Formation and Eocene Wasatch Formation in the Powder River Basin (PRB) in Wyoming and Montana. This framework is graphically presented in 17 intersecting west-east and north-south cross sections across the basin. Also included are: (1) the dataset and all associated digital files and (2) digital files for all figures and table 1 suitable for large-format printing. The purpose of this U.S. Geological Survey (USGS) Open-File Report is to provide rapid dissemination and accessibility of the stratigraphic cross sections and related digital data to USGS customers, especially the U.S. Bureau of Land Management (BLM), to facilitate their modeling of the hydrostratigraphy of the PRB. This report contains a brief summary of the coal-bed correlations and database, and is part of a larger ongoing study that will be available in the near future.

  1. Sequence stratigraphic applications to deep-water exploration in the Makassar Strait, offshore East Kalimantan, Indonesia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malacek, S.J.; Reaves, C.M.; Atmadja, W.S.

    1994-07-01

    A sequence stratigraphic study was conducted to help evaluate the exploration potential of the Makassar PSC, offshore East Kalimantan, Indonesia. The PSC is on the present-day slope in water depths of 500-3000 ft and borders the large oil and gas fields of the Mahakam delta. The study provided important insights on reservoir distribution, trapping style, and seismic hydrocarbon indicators. Lowstand deposition on a slope modified by growth faulting and shale diapirism controlled reservoir distribution within the prospective late Miocene section. Three major lowstand intervals can be seismically defined and tied to deep-water sands in nearby wells where log character andmore » biostratigraphic data support the seismic system tract interpretation. The three intervals appear to correlate with third-order global lowstand events and are consistent with existing sequence stratigraphic schemes for the shelf and upper slope in the Makassar area. Seismic mapping delineated lowstand features, including incised valleys and intraslope to basin-floor thicks. Regional information on positions of middle-late Miocene delta lobes and shelf edges, helped complete the picture for sand sources, transport routes, and depocenters.« less

  2. Study on the application of seismic sedimentology in a stratigraphic-lithologic reservoir in central Junggar Basin

    NASA Astrophysics Data System (ADS)

    Yu, Yixin; Xia, Zhongmou

    2017-06-01

    This paper discusses the research idea of description for stratigraphic-lithologic reservoir based on seismic sedimentology methods. The sandstone reservoir of Jurrassic XiShanyao Formation in Junggar Basin is studied according to the theory and approaches of seismic sedimentology. By making full use of borehole data, the technologies of layer correlation based on the stratigraphic sequence framework, the forward seismic modeling, the stratal slicing and lithologic inversion are applied. It describes the range of denudation line, the distribution characteristics of sedimentary facies of the strata, the vertical and horizontal distribution of sand bodies and the favourable oil-gas bearing prospective area. The results shows that study area are dominated braided delta deposition including underwater distributary channel and distributary bay microfacies, the nip-out lines of the formation are northeast to southwest from north to south, the second Middle Jurassic sand body is the most widely distributed one among three sand bodies, the prospective oil-gas bearing area located in the south part and around the YG2 well area. The study result is effective on the practice of exploration in study area.

  3. Aptian (lower Cretaceous) ammonite biostratigraphy of the Francisco Zarco Dam stratigraphic section (Durango State, northeast Mexico)

    NASA Astrophysics Data System (ADS)

    Moreno-Bedmar, Josep Anton; Barragán Manzo, Ricardo; Company Sempere, Miguel; Bulot, Luc Georges

    2013-03-01

    This work deals with the study of the ammonoid record of a classical stratigraphic section of Aptian age, the Francisco Zarco Dam (Durango State, northeast Mexico). A detailed biostratigraphical analysis considered 1281 specimens systematically sampled on a bed-by-bed basis. Taphonomy, taxonomic composition and paleocology of the studied assemblage, were also stressed. We formally propose an ammonite zonation for this section, which consists of two interval zones, Dufrenoyia justinae and Gargasiceras? adkinsi, one taxon range zone Caseyella aguilerae, and one biohorizon Huastecoceras trispinosoides. Among those biostratigraphic units, three are of new definition. Another topic discussed herein concerns to the problematic definition of the Lower-Upper Aptian boundary using the first stratigraphical appearance of the genus Epicheloniceras. From a paleoecological point of view, we recognized the ammonoid assemblage of the Francisco Zarco Dam section, to be representative of a distal platform environment. Finally, we compared the zonation built for this section with that considered the standard zonation for the Tethyan Domain, concluding that the differences are so substantial that an independent zonation for the Central Atlantic is necessary.

  4. Geophysical, stratigraphic, and flow-zone logs of selected test, monitor, and water-supply wells in Cayuga County, New York

    USGS Publications Warehouse

    Anderson, J. Alton; Williams, John H.; Eckhardt, David A.V.; Miller, Todd S.

    2003-01-01

    Volatile-organic compounds have been detected in water sampled from more than 50 supply wells between the City of Auburn and Village of Union Springs in Cayuga County, New York, and the area was declared a Superfund site in 2002. In 2001-04, geophysical logs were collected from 37 test, monitor, and water-supply wells as a preliminary part of the investigation of volatile-organic compound contamination in the carbonate-bedrock aquifer system. The geophysical logs included gamma, induction, caliper, wellbore image, deviation, fluid resistivity and temperature, and flowmeter. The geophysical logs were analyzed along with core samples and outcrops of the bedrock to define the stratigraphic units and flow zones penetrated by the wells. This report describes the logging methods used in the study and presents the geophysical, stratigraphic, and flow-zone logs.

  5. Stratigraphic response across a structurally dynamic shelf: The latest guadalupian composite sequence at Walnut Canyon, New Mexico, U.S.A

    USGS Publications Warehouse

    Rush, J.; Kerans, C.

    2010-01-01

    The uppermost Yates and Tansill formations (Late Permian), as exposed along Walnut Canyon in Carlsbad Caverns National Park, New Mexico, USA, provide a unique opportunity to document the depositional architecture of a progradational, oversteepened, and mechanically failure-prone carbonate platform. Detailed facies mapping permitted critical assessment of depositional processes operating along this structurally dynamic platform margin. At the shelf crest, thick (12 m), vertically stacked fenestral-pisolite-tepee complexes indicate a stable shoreline. Early lithification of sediments and extensive cementation fostered rapid vertical accretion and allowed the shelf crest to easily adjust to base-level oscillations by stepping landward, stepping seaward, or aggrading. This production imbalance-in combination with syndepositional brittle failure and down-to-the-basin tilting(< 5??)-generated 22 m of depositional relief as measured from nearly horizontal (< 2??) shelf-crest toplap to an outer-shelf downlap surface (< 1??). Mechanical failure of Capitan-equivalent back-reef strata is constrained by stratigraphic architecture, fracture properties, and a highly refined fusulinid biostratigraphic framework. Where fractures tip out, down-to-the-basin rotation is often observed with concurrent seaward thickening of overlying beds, indicating that such fractures functioned as a syndepositional hinge. A facies disjunction and horizontally juxtaposed fusulinid zonation were documented across an 80?? seaward-dipping dilational fracture filled with polymict breccia. An overlying damage zone consisting of spar-cemented fractures nested within silt-filled fractures illustrates periodic reactivation. Field relationships indicate that the dilational fracture approximates a paleoescarpment that resulted from catastrophic failure of the Capitan platform margin. Younger strata onlapped the paleoescarpment and gradually filled the reentrant. This mechanically compromised paleoescarpment

  6. Stratigraphic And Lithofacies Study Of Distal Rain-Triggered Lahars: The Case Of West Coast Of Ecuador

    NASA Astrophysics Data System (ADS)

    Mulas, M.; Chunga, K.; Peña Carpio, E.; Falquez Torres, D. A.; Alcivar, R., Sr.; Lopez Coronel, M. C.

    2015-12-01

    The central zone of the coast of Ecuador at the north of Manabí Province, on the area comprised between Salango and Jama communities, is characterized by the presence of whitish to grey, centimeters to meters thick, consolidated to loose distal ash deposits. Recent archeological studies on Valdivia (3500 BC) and Manteña (800-1500 AC - Harris et al. 2004) civilizations remains link this deposits with the intense eruptive phases that afflicted Ecuador 700-900 years ago (Usselman, 2006). Stratigraphic evidences and bibliographic datations of paleosols (Estrada, 1962; Mothes and Hall, 2008), allowed to estimate that these deposits are linked with the 800 BP eruption of Quilotoa and the following eruptions of Cotopaxi. According to the Smith and Lowe classification (1991), the deposits outcropping on the coast (located at a distance greater than 160 km from the volcanic vents), varied from whitish to grey, loose to weakly consolidated, massive to weakly stratified, centimeters to meters thick, coarse to fine ash matrix layers (diluite streamflow facies) to massive, large angular to sub-rounded siltitic blocks-rich and coarse to medium ash matrix deposits (debris flow facies). These types of lithofacies are associated to a rain-triggered lahar (De Belizal et al., 2013). The presence in some stratigraphic sections of sharp contacts, laminated layers of very fine ash, and also cm-thick sand and silt layers between the ash beds of the same deposits permit to understand that the different pulses were generated in short periods and after a long period. Structures like water pipes imply that the lahar went into the sea (Schneider, 2004), and allow the reconstruction of the paleotopographic condition during the emplacement of these deposits. This study focuses on the characterization of these types of deposits, permit to understand the kind of risk that may affect the towns located on the coast of Ecuador after VEI 4 to 6 eruptions on short time and within years.

  7. ABodyBuilder: Automated antibody structure prediction with data–driven accuracy estimation

    PubMed Central

    Leem, Jinwoo; Dunbar, James; Georges, Guy; Shi, Jiye; Deane, Charlotte M.

    2016-01-01

    ABSTRACT Computational modeling of antibody structures plays a critical role in therapeutic antibody design. Several antibody modeling pipelines exist, but no freely available methods currently model nanobodies, provide estimates of expected model accuracy, or highlight potential issues with the antibody's experimental development. Here, we describe our automated antibody modeling pipeline, ABodyBuilder, designed to overcome these issues. The algorithm itself follows the standard 4 steps of template selection, orientation prediction, complementarity-determining region (CDR) loop modeling, and side chain prediction. ABodyBuilder then annotates the ‘confidence’ of the model as a probability that a component of the antibody (e.g., CDRL3 loop) will be modeled within a root–mean square deviation threshold. It also flags structural motifs on the model that are known to cause issues during in vitro development. ABodyBuilder was tested on 4 separate datasets, including the 11 antibodies from the Antibody Modeling Assessment–II competition. ABodyBuilder builds models that are of similar quality to other methodologies, with sub–Angstrom predictions for the ‘canonical’ CDR loops. Its ability to model nanobodies, and rapidly generate models (∼30 seconds per model) widens its potential usage. ABodyBuilder can also help users in decision–making for the development of novel antibodies because it provides model confidence and potential sequence liabilities. ABodyBuilder is freely available at http://opig.stats.ox.ac.uk/webapps/abodybuilder. PMID:27392298

  8. Automated multi-dimensional purification of tagged proteins.

    PubMed

    Sigrell, Jill A; Eklund, Pär; Galin, Markus; Hedkvist, Lotta; Liljedahl, Pia; Johansson, Christine Markeland; Pless, Thomas; Torstenson, Karin

    2003-01-01

    The capacity for high throughput purification (HTP) is essential in fields such as structural genomics where large numbers of protein samples are routinely characterized in, for example, studies of structural determination, functionality and drug development. Proteins required for such analysis must be pure and homogenous and available in relatively large amounts. AKTA 3D system is a powerful automated protein purification system, which minimizes preparation, run-time and repetitive manual tasks. It has the capacity to purify up to 6 different His6- or GST-tagged proteins per day and can produce 1-50 mg protein per run at >90% purity. The success of automated protein purification increases with careful experimental planning. Protocol, columns and buffers need to be chosen with the final application area for the purified protein in mind.

  9. Modelling and simulating the forming of new dry automated lay-up reinforcements for primary structures

    NASA Astrophysics Data System (ADS)

    Bouquerel, Laure; Moulin, Nicolas; Drapier, Sylvain; Boisse, Philippe; Beraud, Jean-Marc

    2017-10-01

    While weight has been so far the main driver for the development of prepreg based-composites solutions for aeronautics, a new weight-cost trade-off tends to drive choices for next-generation aircrafts. As a response, Hexcel has designed a new dry reinforcement type for aircraft primary structures, which combines the benefits of automation, out-of-autoclave process cost-effectiveness, and mechanical performances competitive to prepreg solutions: HiTape® is a unidirectional (UD) dry carbon reinforcement with thermoplastic veil on each side designed for aircraft primary structures [1-3]. One privileged process route for HiTape® in high volume automated processes consists in forming initially flat dry reinforcement stacks, before resin infusion [4] or injection. Simulation of the forming step aims at predicting the geometry and mechanical properties of the formed stack (so-called preform) for process optimisation. Extensive work has been carried out on prepreg and dry woven fabrics forming behaviour and simulation, but the interest for dry non-woven reinforcements has emerged more recently. Some work has been achieved on non crimp fabrics but studies on the forming behaviour of UDs are seldom and deal with UD prepregs only. Tension and bending in the fibre direction, along with inter-ply friction have been identified as the main mechanisms controlling the HiTape® response during forming. Bending has been characterised using a modified Peirce's flexometer [5] and inter-ply friction study is under development. Anisotropic hyperelastic constitutive models have been selected to represent the assumed decoupled deformation mechanisms. Model parameters are then identified from associated experimental results. For forming simulation, a continuous approach at the macroscopic scale has been selected first, and simulation is carried out in the Zset framework [6] using proper shell finite elements.

  10. Spatial and stratigraphic distribution of water in oil shale of the Green River Formation using Fischer Assay, Piceance Basin, northwestern Colorado

    USGS Publications Warehouse

    Johnson, Ronald C.; Mercier, Tracey J.; Brownfield, Michael E.

    2014-01-01

    The spatial and stratigraphic distribution of water in oil shale of the Eocene Green River Formation in the Piceance Basin of northwestern Colorado was studied in detail using some 321,000 Fischer assay analyses in the U.S. Geological Survey oil-shale database. The oil-shale section was subdivided into 17 roughly time-stratigraphic intervals, and the distribution of water in each interval was assessed separately. This study was conducted in part to determine whether water produced during retorting of oil shale could provide a significant amount of the water needed for an oil-shale industry. Recent estimates of water requirements vary from 1 to 10 barrels of water per barrel of oil produced, depending on the type of retort process used. Sources of water in Green River oil shale include (1) free water within clay minerals; (2) water from the hydrated minerals nahcolite (NaHCO3), dawsonite (NaAl(OH)2CO3), and analcime (NaAlSi2O6.H20); and (3) minor water produced from the breakdown of organic matter in oil shale during retorting. The amounts represented by each of these sources vary both stratigraphically and areally within the basin. Clay is the most important source of water in the lower part of the oil-shale interval and in many basin-margin areas. Nahcolite and dawsonite are the dominant sources of water in the oil-shale and saline-mineral depocenter, and analcime is important in the upper part of the formation. Organic matter does not appear to be a major source of water. The ratio of water to oil generated with retorting is significantly less than 1:1 for most areas of the basin and for most stratigraphic intervals; thus water within oil shale can provide only a fraction of the water needed for an oil-shale industry.

  11. Spatial and stratigraphic distribution of water in oil shale of the Green River Formation using Fischer assay, Piceance Basin, northwestern Colorado

    USGS Publications Warehouse

    Johnson, Ronald C.; Mercier, Tracey J.; Brownfield, Michael E.

    2014-01-01

    The spatial and stratigraphic distribution of water in oil shale of the Eocene Green River Formation in the Piceance Basin of northwestern Colorado was studied in detail using some 321,000 Fischer assay analyses in the U.S. Geological Survey oil-shale database. The oil-shale section was subdivided into 17 roughly time-stratigraphic intervals, and the distribution of water in each interval was assessed separately. This study was conducted in part to determine whether water produced during retorting of oil shale could provide a significant amount of the water needed for an oil-shale industry. Recent estimates of water requirements vary from 1 to 10 barrels of water per barrel of oil produced, depending on the type of retort process used. Sources of water in Green River oil shale include (1) free water within clay minerals; (2) water from the hydrated minerals nahcolite (NaHCO3), dawsonite (NaAl(OH)2CO3), and analcime (NaAlSi2O6.H20); and (3) minor water produced from the breakdown of organic matter in oil shale during retorting. The amounts represented by each of these sources vary both stratigraphically and areally within the basin. Clay is the most important source of water in the lower part of the oil-shale interval and in many basin-margin areas. Nahcolite and dawsonite are the dominant sources of water in the oil-shale and saline-mineral depocenter, and analcime is important in the upper part of the formation. Organic matter does not appear to be a major source of water. The ratio of water to oil generated with retorting is significantly less than 1:1 for most areas of the basin and for most stratigraphic intervals; thus water within oil shale can provide only a fraction of the water needed for an oil-shale industry.

  12. Lithostratigraphy and volcanology of the Serra Geral Group, Paraná-Etendeka Igneous Province in Southern Brazil: Towards a formal stratigraphical framework

    NASA Astrophysics Data System (ADS)

    Rossetti, Lucas; Lima, Evandro F.; Waichel, Breno L.; Hole, Malcolm J.; Simões, Matheus S.; Scherer, Claiton M. S.

    2018-04-01

    The volcanic rocks of the Lower Cretaceous Paraná-Etendeka Igneous Province, in Brazil, are grouped in the Serra Geral Group. The province can be chemically divided into low-TiO2, and high-TiO2. In southern Brazil, the low-TiO2 lava pile reaches a thickness of 1 km and is formed of heterogeneous lava packages here divided into four lava formations. Torres Formation (TF) is characterized by chemically more primitive basaltic (> 5 wt% MgO) compound pahoehoe flow fields; these lavas stratigraphically overly aeolian sandstones of Botucatu Formation and represent the onset of the volcanic activity. Vale do Sol Formation (VSF) groups vertically stacked sheet-like rubbly pahoehoe basaltic andesites (SiO2 > 51 wt%; MgO < 5 wt%). These lavas covered the former basalts in the Torres Syncline axis and pinch out towards southwest and represent the most voluminous mafic lava flows. Dacites and rhyolites of Palmas Formation (PF) overlay VSF flows in the central and eastern outcrop area and rest directly upon TF lavas in the west. The acidic units were emplaced as lava domes and widespread tabular lava flows. Esmeralda Formation (EF) is the upper stratigraphic unit and it is formed by a basaltic pahoehoe flow field emplaced during the waning phase of volcanic activity of the low-TiO2 lava sequence. Sedimentary interbeds are preserved throughout the whole lava pile and were deposited during quiescence periods of volcanic activity, and represent important stratigraphic markers (e.g. TF-VSF contact). The newly proposed stratigraphy provides promptly recognized stratigraphic units in a regional framework of fundamental importance for future correlations and provide vital information in the understanding of how the Paraná-Etendeka Igneous Province evolved through time.

  13. Automated peak picking and peak integration in macromolecular NMR spectra using AUTOPSY.

    PubMed

    Koradi, R; Billeter, M; Engeli, M; Güntert, P; Wüthrich, K

    1998-12-01

    A new approach for automated peak picking of multidimensional protein NMR spectra with strong overlap is introduced, which makes use of the program AUTOPSY (automated peak picking for NMR spectroscopy). The main elements of this program are a novel function for local noise level calculation, the use of symmetry considerations, and the use of lineshapes extracted from well-separated peaks for resolving groups of strongly overlapping peaks. The algorithm generates peak lists with precise chemical shift and integral intensities, and a reliability measure for the recognition of each peak. The results of automated peak picking of NOESY spectra with AUTOPSY were tested in combination with the combined automated NOESY cross peak assignment and structure calculation routine NOAH implemented in the program DYANA. The quality of the resulting structures was found to be comparable with those from corresponding data obtained with manual peak picking. Copyright 1998 Academic Press.

  14. Human communication needs and organizational productivity: the potential impact of office automation.

    PubMed

    Culnan, M J; Bair, J H

    1983-05-01

    Much of what white collar workers do in offices is communication-related. White collar workers make up the majority of the labor force in the United States today and the majority of current labor costs. Because office automation represents more productive structured techniques for handling both written and oral communication, office automation therefore offers the potential to make organizations more productive by improving organizational communication. This article: (1) defines communication, (2) identifies the potential benefits to be realized from implementing office automation, and (3) offers caveats related to the implementation of office automation systems. Realization of the benefits of office automation depends upon the degree to which new modes of communication may be successfully substituted for traditional modes.

  15. Automated identification of basalt spectra in Clementine lunar data

    NASA Astrophysics Data System (ADS)

    Antonenko, I.; Osinski, G. R.

    2011-06-01

    The identification of fresh basalt spectra plays an important role in lunar stratigraphic studies; however, the process can be time consuming and labor intensive. Thus motivated, we developed an empirically derived algorithm for the automated identification of fresh basalt spectra from Clememtine UVVIS data. This algorithm has the following four parameters and limits: BC Ratio=3(R950-R900)/(R900-R750)<1.1, CD Delta=(R1000-R950)/R750-1.09(R950-R900)/R750>0.003 and <0.06, B Slope=(R900-R750)/(3R750)<-0.012, and Band Depth=(R750-R950)/(R750-R415)>0.1, where R750 represents the unnormalized reflectance of the 750 nm Clementine band, and so on. Algorithm results were found to be accurate to within an error of 4.5% with respect to visual classification, though olivine spectra may be under-represented. Overall, fresh basalts identified by the algorithm are consistent with expectations and previous work in the Mare Humorum area, though accuracy in other areas has not yet been tested. Great potential exists in using this algorithm for identifying craters that have excavated basalts, estimating the thickness of mare and cryptomare deposits, and other applications.

  16. A Detailed Study of the Delacroix Island Major Fault and Its Role on Stratigraphic Horizons from the Middle Miocene to Present

    NASA Astrophysics Data System (ADS)

    Levesh, J. L.; McLindon, C.; Kulp, M. A.

    2017-12-01

    An in-depth field study of the Delacroix Island producing field illustrates the evolution of the main East-West trending Delacroix Island fault over the last thirteen million years. Well log correlation and 3-D seismic interpretation of eighteen bio-stratigraphic horizons across the fault reveal a range of stratigraphic thicknesses. A cross section, created with wells upthrown and downthrown to the fault, visually demonstrates varying degrees of thickening and displacement of the stratigraphic intervals across the fault. One upthrown and one downthrown well, with well log curve data up to 30 meters below the surface, were used to calculate interval thicknesses between the main tops as well as five more Pliocene/Pleistocene biostratigraphic markers. Isopach maps, created with these interval thicknesses, depict two styles of interval thickening both of which indicate differential subsidence across the fault. An interval thickness analysis was plotted in both depth and time as well as plots showing the rate of sediment accumulation and depth versus fault displacement. A lineation on the marsh surface consistent with a projection of the fault plane suggests that the fault movement has been episodically continuous to the present and that recent movement may have played a role in submerging the downthrown side of the surface fault trace.

  17. NASA space station automation: AI-based technology review

    NASA Technical Reports Server (NTRS)

    Firschein, O.; Georgeff, M. P.; Park, W.; Neumann, P.; Kautz, W. H.; Levitt, K. N.; Rom, R. J.; Poggio, A. A.

    1985-01-01

    Research and Development projects in automation for the Space Station are discussed. Artificial Intelligence (AI) based automation technologies are planned to enhance crew safety through reduced need for EVA, increase crew productivity through the reduction of routine operations, increase space station autonomy, and augment space station capability through the use of teleoperation and robotics. AI technology will also be developed for the servicing of satellites at the Space Station, system monitoring and diagnosis, space manufacturing, and the assembly of large space structures.

  18. Flexible automation of cell culture and tissue engineering tasks.

    PubMed

    Knoll, Alois; Scherer, Torsten; Poggendorf, Iris; Lütkemeyer, Dirk; Lehmann, Jürgen

    2004-01-01

    Until now, the predominant use cases of industrial robots have been routine handling tasks in the automotive industry. In biotechnology and tissue engineering, in contrast, only very few tasks have been automated with robots. New developments in robot platform and robot sensor technology, however, make it possible to automate plants that largely depend on human interaction with the production process, e.g., for material and cell culture fluid handling, transportation, operation of equipment, and maintenance. In this paper we present a robot system that lends itself to automating routine tasks in biotechnology but also has the potential to automate other production facilities that are similar in process structure. After motivating the design goals, we describe the system and its operation, illustrate sample runs, and give an assessment of the advantages. We conclude this paper by giving an outlook on possible further developments.

  19. Automated data collection based on RoboDiff at the ESRF beamline MASSIF-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nurizzo, Didier, E-mail: Didier.nurizzo@esrf.fr; Guichard, Nicolas; McSweeney, Sean

    2016-07-27

    The European Synchrotron Radiation Facility has a long standing history in the automation of experiments in Macromolecular Crystallography. MASSIF-1 (Massively Automated Sample Screening and evaluation Integrated Facility), a beamline constructed as part of the ESRF Upgrade Phase I program, has been open to the external user community since July 2014 and offers a unique completely automated data collection service to both academic and industrial structural biologists.

  20. Automated Processing of Imaging Data through Multi-tiered Classification of Biological Structures Illustrated Using Caenorhabditis elegans.

    PubMed

    Zhan, Mei; Crane, Matthew M; Entchev, Eugeni V; Caballero, Antonio; Fernandes de Abreu, Diana Andrea; Ch'ng, QueeLim; Lu, Hang

    2015-04-01

    Quantitative imaging has become a vital technique in biological discovery and clinical diagnostics; a plethora of tools have recently been developed to enable new and accelerated forms of biological investigation. Increasingly, the capacity for high-throughput experimentation provided by new imaging modalities, contrast techniques, microscopy tools, microfluidics and computer controlled systems shifts the experimental bottleneck from the level of physical manipulation and raw data collection to automated recognition and data processing. Yet, despite their broad importance, image analysis solutions to address these needs have been narrowly tailored. Here, we present a generalizable formulation for autonomous identification of specific biological structures that is applicable for many problems. The process flow architecture we present here utilizes standard image processing techniques and the multi-tiered application of classification models such as support vector machines (SVM). These low-level functions are readily available in a large array of image processing software packages and programming languages. Our framework is thus both easy to implement at the modular level and provides specific high-level architecture to guide the solution of more complicated image-processing problems. We demonstrate the utility of the classification routine by developing two specific classifiers as a toolset for automation and cell identification in the model organism Caenorhabditis elegans. To serve a common need for automated high-resolution imaging and behavior applications in the C. elegans research community, we contribute a ready-to-use classifier for the identification of the head of the animal under bright field imaging. Furthermore, we extend our framework to address the pervasive problem of cell-specific identification under fluorescent imaging, which is critical for biological investigation in multicellular organisms or tissues. Using these examples as a guide, we envision

  1. Neoproterozoic–Cambrian stratigraphic framework of the Anti-Atlas and Ouzellagh promontory (High Atlas), Morocco

    USGS Publications Warehouse

    Alvaro, Jose Javier; Benziane, Fouad; Thomas, Robert; Walsh, Gregory J.; Yazidi, Abdelaziz

    2014-01-01

    In the last two decades, great progress has been made in the geochronological, chrono- and chemostratigraphic control of the Neoproterozoic and Cambrian from the Anti-Atlas Ranges and the Ouzellagh promontory (High Atlas). As a result, the Neoproterozoic is lithostratigraphically subdivided into: (i) the Lkest-Taghdout Group (broadly interpreted at c. 800–690 Ma) representative of rift-to-passive margin conditions on the northern West African craton; (ii) the Iriri (c. 760–740 Ma), Bou Azzer (c. 762–697 Ma) and Saghro (c. 760?–610 Ma) groups, the overlying Anezi, Bou Salda, Dadès and Tiddiline formations localized in fault-grabens, and the Ouarzazate Supergroup (c. 615–548 Ma), which form a succession of volcanosedimentary complexes recording the onset of the Pan-African orogeny and its aftermath; and (iii) the Taroudant (the Ediacaran–Cambrian boundary lying in the Tifnout Member of the Adoudou Formation), Tata, Feijas Internes and Tabanite groups that have recorded development of the late Ediacaran–Cambrian Atlas Rift. Recent discussions of Moroccan strata to select new global GSSPs by the International Subcommissions on Ediacaran and Cambrian Stratigraphy have raised the stratigraphic interest in this region. A revised and updated stratigraphic framework is proposed here to assist the tasks of both subcommissions and to fuel future discussions focused on different geological aspects of the Neoproterozoic–Cambrian time span.

  2. Spectral and stratigraphic mapping of hydrated minerals associated with interior layered deposits near the southern wall of Melas Chasma, Mars

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Goudge, Timothy A.; Catalano, Jeffrey G.; Wang, Alian

    2018-03-01

    Orbital remote sensing data acquired from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) onboard Mars Reconnaissance Orbiter (MRO), in conjunction with other datasets, are used to perform detailed spectral and stratigraphic analyses over a portion of south Melas Chasma, Mars. The Discrete Ordinate Radiative Transfer (DISORT) model is used to retrieve atmospherically corrected single scattering albedos from CRISM I/F data for mineral identification. A sequence of interbedded poly- and monohydrated sulfates associated with interior layered deposits (ILDs) is identified and mapped. Analyses from laboratory experiments and spectral unmixing of CRISM hyperspectral data support the hypothesis of precipitation and dehydration of multiple inputs of complex Mg-Ca-Fe-SO4-Cl brines. In this scenario, the early precipitated Mg sulfates could dehydrate into monohydrated sulfate due to catalytic effects, and the later-precipitated Mg sulfates from the late-stage "clean" brine could terminate their dehydration at mid-degree of hydration to form a polyhydrated sulfate layer due to depletion of the catalytic species (e.g., Ca, Fe, and Cl). Distinct jarosite-bearing units are identified stratigraphically above the hydrated sulfate deposits. These are hypothesized to have formed either by oxidation of a fluid containing Fe(II) and SO4, or by leaching of soluble phases from precursor intermixed jarosite-Mg sulfate units that may have formed during the later stages of deposition of the hydrated sulfate sequence. Results from stratigraphic analysis of the ILDs show that the layers have a consistent northward dip towards the interior of the Melas Chasma basin, a mean dip angle of ∼6°, and neighboring strata that are approximately parallel. These strata are interpreted as initially sub-horizontal layers of a subaqueous, sedimentary evaporite deposits that underwent post-depositional tilting from slumping into the Melas Chasma basin. The interbedded hydrated sulfate

  3. Multi-objective design optimization of antenna structures using sequential domain patching with automated patch size determination

    NASA Astrophysics Data System (ADS)

    Koziel, Slawomir; Bekasiewicz, Adrian

    2018-02-01

    In this article, a simple yet efficient and reliable technique for fully automated multi-objective design optimization of antenna structures using sequential domain patching (SDP) is discussed. The optimization procedure according to SDP is a two-step process: (i) obtaining the initial set of Pareto-optimal designs representing the best possible trade-offs between considered conflicting objectives, and (ii) Pareto set refinement for yielding the optimal designs at the high-fidelity electromagnetic (EM) simulation model level. For the sake of computational efficiency, the first step is realized at the level of a low-fidelity (coarse-discretization) EM model by sequential construction and relocation of small design space segments (patches) in order to create a path connecting the extreme Pareto front designs obtained beforehand. The second stage involves response correction techniques and local response surface approximation models constructed by reusing EM simulation data acquired in the first step. A major contribution of this work is an automated procedure for determining the patch dimensions. It allows for appropriate selection of the number of patches for each geometry variable so as to ensure reliability of the optimization process while maintaining its low cost. The importance of this procedure is demonstrated by comparing it with uniform patch dimensions.

  4. Advanced in In Situ Inspection of Automated Fiber Placement Systems

    NASA Technical Reports Server (NTRS)

    Juarez, Peter D.; Cramer, K. Elliott; Seebo, Jeffrey P.

    2016-01-01

    Automated Fiber Placement (AFP) systems have been developed to help take advantage of the tailorability of composite structures in aerospace applications. AFP systems allow the repeatable placement of uncured, spool fed, preimpregnated carbon fiber tape (tows) onto substrates in desired thicknesses and orientations. This automated process can incur defects, such as overlapping tow lines, which can severely undermine the structural integrity of the part. Current defect detection and abatement methods are very labor intensive, and still mostly rely on human manual inspection. Proposed is a thermographic in situ inspection technique which monitors tow placement with an on board thermal camera using the preheated substrate as a through transmission heat source. An investigation of the concept is conducted, and preliminary laboratory results are presented. Also included will be a brief overview of other emerging technologies that tackle the same issue. Keywords: Automated Fiber Placement, Manufacturing defects, Thermography

  5. Ichnology applied to sequence stratigraphic analysis of Siluro-Devonian mud-dominated shelf deposits, Paraná Basin, Brazil

    NASA Astrophysics Data System (ADS)

    Sedorko, Daniel; Netto, Renata G.; Savrda, Charles E.

    2018-04-01

    Previous studies of the Paraná Supersequence (Furnas and Ponta Grossa formations) of the Paraná Basin in southern Brazil have yielded disparate sequence stratigraphic interpretations. An integrated sedimentological, paleontological, and ichnological model was created to establish a refined sequence stratigraphic framework for this succession, focusing on the Ponta Grossa Formation. Twenty-nine ichnotaxa are recognized in the Ponta Grossa Formation, recurring assemblages of which define five trace fossil suites that represent various expressions of the Skolithos, Glossifungites and Cruziana ichnofacies. Physical sedimentologic characteristics and associated softground ichnofacies provide the basis for recognizing seven facies that reflect a passive relationship to bathymetric gradients from shallow marine (shoreface) to offshore deposition. The vertical distribution of facies provides the basis for dividing the Ponta Grossa Formation into three major (3rd-order) depositional sequences- Siluro-Devonian and Devonian I and II-each containing a record of three to seven higher-order relative sea-level cycles. Major sequence boundaries, commonly coinciding with hiatuses recognized from previously published biostratigraphic data, are locally marked by firmground Glossifungites Ichnofacies associated with submarine erosion. Maximum transgressive horizons are prominently marked by unbioturbated or weakly bioturbated black shales. By integrating observations of the Ponta Grossa Formation with those recently made on the underlying marginal- to shallow-marine Furnas Formation, the entire Paraná Supersequence can be divided into four disconformity-bound sequences: a Lower Silurian (Llandovery-Wenlock) sequence, corresponding to lower and middle units of the Furnas; a Siluro-Devonian sequence (?Pridoli-Early Emsian), and Devonian sequences I (Late Emsian-Late Eifelian) and II (Late Eifelian-Early Givetian). Stratigraphic positions of sequence boundaries generally coincide with

  6. Final Pleistocene and Holocene pollen stratigraphic sequence from the Cloquet River area, St. Louis Co. , NE Minnesota

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hill, C.L.; Rapp, G.R. Jr.; Huber, J.K.

    A five-meter pollen sequence from a bog has been studied as part of a project concerned with the late-Quaternary paleoenvironmental setting and prehistory of northeastern Minnesota. The stratigraphic sequence is situated on an outwash plain derived from the Automba phase of glaciation (ca. 15,000 B.P.) and is located near a series of surface archaeological localities containing possible late Paleoindian lithic assemblages. Loss-on-ignition and particle size analyses reveal that the top section of the core, to a depth of about 350 cm, is composed predominantly of organics, the remaining 150 cm is dominated by mud. Radicarbon ages of 9270 +/- 190more » B.P. (UCR-1825) for the 350-355 cm interval, and 9420 +/- 180 (UCR-1826) for the 350-364 cm interval, were obtained. Data derived from pollen counts made at 20 cm intervals throughout the sequence indicate the core can be divided into several pollen-stratigraphic zones. The lowest zone, from the base of the core to about 440 cm, contains Cyperaceae (initially at about 60% total pollen) and is also characterized by Picea and Salix. (ca5%). Above this, there is a zone which ends at about 360 cm and contains a Betula peak (>65%). These two zones are considered to reflect the presence of tundra-like and dwarf-birch tundra vegetational regimes in the area during the late Pleistocene. Several pollen stratigraphic zones above 360 cm provide an indication of the Holocene vegetational setting, and show the increasing dominance of Pinus. The paleoenvironmental record obtained from this core, along with studies of the geologic setting, late Quaternary glacial sequence, and physiographic situation of archaeological localities, may help to elucidate the conditions prevalent during this time and provide a basis for a clearer understanding of the prehistoric ecology of northeastern Minnesota.« less

  7. Identifying coseismic subsidence in tidal-wetland stratigraphic sequences at the Cascadia subduction zone of western North America

    USGS Publications Warehouse

    Nelson, Alan R.; Shennan, Ian; Long, Antony J.

    1996-01-01

    Tidal-wetland stratigraphy reveals that great plate boundary earthquakes have caused hundreds of kilometers of coast to subside at the Cascadia subduction zone. However, determining earthquake recurrence intervals and mapping the coastal extent of past great earthquake ruptures in this region are complicated by the effects of many sedimentologic, hydrographic, and oceanographic processes that occur on the coasts of tectonically passive as well as active continental margins. Tidal-wetland stratigraphy at many Cascadia estuaries differs little from that at similar sites on passive-margin coasts where stratigraphic sequences form through nonseismic processes unrelated to coseismic land level changes. Methods developed through study of similar stratigraphic sequences in Europe provide a framework for investigating the Cascadia estuarine record. Five kinds of criteria must be evaluated when inferring regional coastal subsidence due to great plate boundary earthquakes: the suddenness and amount of submergence, the lateral extent of submerged tidal-wetland soils, the coincidence of submergence with tsunami deposits, and the degree of synchroneity of submergence events at widely spaced sites. Evaluation of such criteria at the Cascadia subduction zone indicates regional coastal subsidence during at least two great earthquakes. Evidence for a coseismic origin remains equivocal, however, for the many peat-mud contacts in Cascadia stratigraphic sequences that lack (1) contrasts in lithology or fossils indicative of more than half a meter of submergence, (2) well-studied tsunami deposits, or (3) precise ages needed for regional correlation. Paleoecologic studies of fossil assemblages are particularly important in estimating the size of sudden sea level changes recorded by abrupt peat-mud contacts and in helping to distinguish erosional and gradually formed contacts from coseismic contacts. Reconstruction of a history of great earthquakes for the Cascadia subduction zone will

  8. Stratigraphic correlations in mid- to late-Proterozoic carbonates of the Democratic Republic of Congo using magnetic susceptibility

    NASA Astrophysics Data System (ADS)

    Delpomdor, Franck R. A.; Devleeschouwer, Xavier; Spassov, Simo; Préat, Alain R.

    2017-04-01

    In this paper, we have tested the application of magnetic susceptibility measurements in Cu-Ag-Zn-Pb-(Fe)-mineralized carbonates of the BIe subgroup (Democratic Republic of Congo) as an efficient tool for regional and global high-resolution stratigraphic correlations in the Neoproterozoic marine carbonates. To achieve this goal, we integrate the low-field magnetic susceptibility (XLF) data with facies analyses, geochemistry and isotope stratigraphy. The microfacies analyses of two cores, Tshinyama#S70 and Kafuku#15, drilled in the early Neoproterozoic carbonates of the Mbuji-Mayi Supergroup reveal a deep carbonate ramp setting associated with a microbial/stromatolitic mid-ramp environment. High-resolution stratigraphic correlations using magnetic susceptibility and C-isotope curves established for both cores, 190 km apart, suggest a sedimentary hiatus at the base of the Tshinyama#S70 succession. C-O and Sr isotopes and Sr/Ca and Fe abundances show that a diagenetic meteoric overprint affected the series of the Tshinyama#S70 core and a thermal effect related to mineralizing fluids affected the Kafuku#15 core carbonates.

  9. Radiolarian biostratigraphic data from the Casiguran Ophiolite, Northern Sierra Madre, Luzon, Philippines: Stratigraphic and tectonic implications

    NASA Astrophysics Data System (ADS)

    Queano, Karlo L.; Marquez, Edanjarlo J.; Aitchison, Jonathan C.; Ali, Jason R.

    2013-03-01

    Results from the first detailed radiolarian biostratigraphic study conducted in Luzon are reported. The data were obtained from cherts associated with the Casiguran Ophiolite, a dismembered ophiolite mass consisting of serpentinized peridotites, gabbros, dolerite dikes and pillow basalts exposed along the eastern coast of the Northern Sierra Madre, Luzon, Philippines. Cherts and limestone interbeds conformably overlie the ophiolite. The radiolarian assemblages from the cherts constrain the stratigraphic range of the cherts to the Lower Cretaceous (upper Barremian-lower Aptian to Albian). This new biostratigraphic result is in contrast with the Upper Cretaceous stratigraphic range previously reported in the region. Radiolarian biostratigraphic results from the Casiguran Ophiolite provide additional evidence for the existence of Mesozoic oceanic substratum upon which Luzon and neighboring regions within the Philippine archipelago were likely built. Interestingly, the result closely resembles those reported for the ophiolite in southeastern Luzon as well as the oceanic crust of the Huatung Basin situated east of Taiwan and the ophiolites in eastern Indonesia. In light of this, along with previously gathered geochemical data from the ophiolites, a common provenance is being looked into for these crust-upper mantle sequences in the western Pacific region.

  10. Tectono-stratigraphic evolution of normal fault zones: Thal Fault Zone, Suez Rift, Egypt

    NASA Astrophysics Data System (ADS)

    Leppard, Christopher William

    The evolution of linkage of normal fault populations to form continuous, basin bounding normal fault zones is recognised as an important control on the stratigraphic evolution of rift-basins. This project aims to investigate the temporal and spatial evolution of normal fault populations and associated syn-rift deposits from the initiation of early-formed, isolated normal faults (rift-initiation) to the development of a through-going fault zone (rift-climax) by documenting the tectono-stratigraphic evolution of the Sarbut EI Gamal segment of the exceptionally well-exposed Thai fault zone, Suez Rift, Egypt. A number of dated stratal surfaces mapped around the syn-rift depocentre of the Sarbut El Gamal segment allow constraints to be placed on the timing and style of deformation, and the spatial variability of facies along this segment of the fault zone. Data collected indicates that during the first 3.5 My of rifting the structural style was characterised by numerous, closely spaced, short (< 3 km), low displacement (< 200 m) synthetic and antithetic normal faults within 1 - 2 km of the present-day fault segment trace, accommodating surface deformation associated with the development of a fault propagation monocline above the buried, pre-cursor strands of the Sarbut El Gamal fault segment. The progressive localisation of displacement onto the fault segment during rift-climax resulted in the development of a major, surface-breaking fault 3.5 - 5 My after the onset of rifting and is recorded by the death of early-formed synthetic and antithetic faults up-section, and thickening of syn-rift strata towards the fault segment. The influence of intrabasinal highs at the tips of the Sarbut EI Gamal fault segment on the pre-rift sub-crop level, combined with observations from the early-formed structures and coeval deposits suggest that the overall length of the fault segment was fixed from an early stage. The fault segment is interpreted to have grown through rapid lateral

  11. SU-C-9A-02: Structured Noise Index as An Automated Quality Control for Nuclear Medicine: A Two Year Experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nelson, J; Christianson, O; Samei, E

    Purpose: Flood-field uniformity evaluation is an essential element in the assessment of nuclear medicine (NM) gamma cameras. It serves as the central element of the quality control (QC) program, acquired and analyzed on a daily basis prior to clinical imaging. Uniformity images are traditionally analyzed using pixel value-based metrics which often fail to capture subtle structure and patterns caused by changes in gamma camera performance requiring additional visual inspection which is subjective and time demanding. The goal of this project was to develop and implement a robust QC metrology for NM that is effective in identifying non-uniformity issues, reporting issuesmore » in a timely manner for efficient correction prior to clinical involvement, all incorporated into an automated effortless workflow, and to characterize the program over a two year period. Methods: A new quantitative uniformity analysis metric was developed based on 2D noise power spectrum metrology and confirmed based on expert observer visual analysis. The metric, termed Structured Noise Index (SNI) was then integrated into an automated program to analyze, archive, and report on daily NM QC uniformity images. The effectiveness of the program was evaluated over a period of 2 years. Results: The SNI metric successfully identified visually apparent non-uniformities overlooked by the pixel valuebased analysis methods. Implementation of the program has resulted in nonuniformity identification in about 12% of daily flood images. In addition, due to the vigilance of staff response, the percentage of days exceeding trigger value shows a decline over time. Conclusion: The SNI provides a robust quantification of the NM performance of gamma camera uniformity. It operates seamlessly across a fleet of multiple camera models. The automated process provides effective workflow within the NM spectra between physicist, technologist, and clinical engineer. The reliability of this process has made it the

  12. Automated inspection of bread and loaves

    NASA Astrophysics Data System (ADS)

    Batchelor, Bruce G.

    1993-08-01

    The prospects for building practical automated inspection machines, capable of detecting the following faults in ordinary, everyday loaves are reviewed: (1) foreign bodies, using X-rays, (2) texture changes, using glancing illumination, mathematical morphology and Neural Net learning techniques, and (3) shape deformations, using structured lighting and simple geometry.

  13. Automated Docking Screens: A Feasibility Study

    PubMed Central

    2009-01-01

    Molecular docking is the most practical approach to leverage protein structure for ligand discovery, but the technique retains important liabilities that make it challenging to deploy on a large scale. We have therefore created an expert system, DOCK Blaster, to investigate the feasibility of full automation. The method requires a PDB code, sometimes with a ligand structure, and from that alone can launch a full screen of large libraries. A critical feature is self-assessment, which estimates the anticipated reliability of the automated screening results using pose fidelity and enrichment. Against common benchmarks, DOCK Blaster recapitulates the crystal ligand pose within 2 Å rmsd 50−60% of the time; inferior to an expert, but respectrable. Half the time the ligand also ranked among the top 5% of 100 physically matched decoys chosen on the fly. Further tests were undertaken culminating in a study of 7755 eligible PDB structures. In 1398 cases, the redocked ligand ranked in the top 5% of 100 property-matched decoys while also posing within 2 Å rmsd, suggesting that unsupervised prospective docking is viable. DOCK Blaster is available at http://blaster.docking.org. PMID:19719084

  14. Automated docking screens: a feasibility study.

    PubMed

    Irwin, John J; Shoichet, Brian K; Mysinger, Michael M; Huang, Niu; Colizzi, Francesco; Wassam, Pascal; Cao, Yiqun

    2009-09-24

    Molecular docking is the most practical approach to leverage protein structure for ligand discovery, but the technique retains important liabilities that make it challenging to deploy on a large scale. We have therefore created an expert system, DOCK Blaster, to investigate the feasibility of full automation. The method requires a PDB code, sometimes with a ligand structure, and from that alone can launch a full screen of large libraries. A critical feature is self-assessment, which estimates the anticipated reliability of the automated screening results using pose fidelity and enrichment. Against common benchmarks, DOCK Blaster recapitulates the crystal ligand pose within 2 A rmsd 50-60% of the time; inferior to an expert, but respectrable. Half the time the ligand also ranked among the top 5% of 100 physically matched decoys chosen on the fly. Further tests were undertaken culminating in a study of 7755 eligible PDB structures. In 1398 cases, the redocked ligand ranked in the top 5% of 100 property-matched decoys while also posing within 2 A rmsd, suggesting that unsupervised prospective docking is viable. DOCK Blaster is available at http://blaster.docking.org .

  15. Automated compound classification using a chemical ontology.

    PubMed

    Bobach, Claudia; Böhme, Timo; Laube, Ulf; Püschel, Anett; Weber, Lutz

    2012-12-29

    Classification of chemical compounds into compound classes by using structure derived descriptors is a well-established method to aid the evaluation and abstraction of compound properties in chemical compound databases. MeSH and recently ChEBI are examples of chemical ontologies that provide a hierarchical classification of compounds into general compound classes of biological interest based on their structural as well as property or use features. In these ontologies, compounds have been assigned manually to their respective classes. However, with the ever increasing possibilities to extract new compounds from text documents using name-to-structure tools and considering the large number of compounds deposited in databases, automated and comprehensive chemical classification methods are needed to avoid the error prone and time consuming manual classification of compounds. In the present work we implement principles and methods to construct a chemical ontology of classes that shall support the automated, high-quality compound classification in chemical databases or text documents. While SMARTS expressions have already been used to define chemical structure class concepts, in the present work we have extended the expressive power of such class definitions by expanding their structure-based reasoning logic. Thus, to achieve the required precision and granularity of chemical class definitions, sets of SMARTS class definitions are connected by OR and NOT logical operators. In addition, AND logic has been implemented to allow the concomitant use of flexible atom lists and stereochemistry definitions. The resulting chemical ontology is a multi-hierarchical taxonomy of concept nodes connected by directed, transitive relationships. A proposal for a rule based definition of chemical classes has been made that allows to define chemical compound classes more precisely than before. The proposed structure-based reasoning logic allows to translate chemistry expert knowledge into a

  16. Automated compound classification using a chemical ontology

    PubMed Central

    2012-01-01

    Background Classification of chemical compounds into compound classes by using structure derived descriptors is a well-established method to aid the evaluation and abstraction of compound properties in chemical compound databases. MeSH and recently ChEBI are examples of chemical ontologies that provide a hierarchical classification of compounds into general compound classes of biological interest based on their structural as well as property or use features. In these ontologies, compounds have been assigned manually to their respective classes. However, with the ever increasing possibilities to extract new compounds from text documents using name-to-structure tools and considering the large number of compounds deposited in databases, automated and comprehensive chemical classification methods are needed to avoid the error prone and time consuming manual classification of compounds. Results In the present work we implement principles and methods to construct a chemical ontology of classes that shall support the automated, high-quality compound classification in chemical databases or text documents. While SMARTS expressions have already been used to define chemical structure class concepts, in the present work we have extended the expressive power of such class definitions by expanding their structure-based reasoning logic. Thus, to achieve the required precision and granularity of chemical class definitions, sets of SMARTS class definitions are connected by OR and NOT logical operators. In addition, AND logic has been implemented to allow the concomitant use of flexible atom lists and stereochemistry definitions. The resulting chemical ontology is a multi-hierarchical taxonomy of concept nodes connected by directed, transitive relationships. Conclusions A proposal for a rule based definition of chemical classes has been made that allows to define chemical compound classes more precisely than before. The proposed structure-based reasoning logic allows to translate

  17. Understanding Mississippi Delta Subsidence through Stratigraphic and Geotechnical Analysis of a Continuous Holocene Core at a Subsidence Superstation

    NASA Astrophysics Data System (ADS)

    Bridgeman, J.; Tornqvist, T. E.; Jafari, N.; Allison, M. A.

    2017-12-01

    Land-surface subsidence can be a major contributor to the relative sea-level rise that is threatening coastal communities. Loosely constrained subsidence rate estimates across the Mississippi Delta make it difficult to differentiate between subsidence mechanisms and complicate modeling efforts. New data from a nearly 40 m long, 12 cm diameter core taken during the installation of a subsidence monitoring superstation near the Mississippi River, SW of New Orleans, provides insight into the stratigraphic and geotechnical properties of the Holocene succession. Stratigraphically, the core can be grouped into three sections. The top 12 m is dominated by clastic overbank sediment with interspersed organic-rich layers. The middle section, 12-35 m consists predominately of mud, and the bottom section, 35-38.7 m, is marked by a transition into a Holocene-aged basal peat (11,350-11,190 cal BP) which overlies densely packed Pleistocene sediment. Radiocarbon and OSL ages show up to 6 m of vertical displacement since 3,000 cal BP. We infer that most of this was due to compaction of the thick underlying mud package. The top ­­­­­ 70 cm of the core is a peat that represents the modern marsh surface and is inducing minimal surface loading. This is consistent with the negligible shallow subsidence rate as seen at a nearby rod-surface elevation table - marker horizon station and the initial strainmeter data. Future compaction scenarios for the superstation can be modeled from the stratigraphic and geotechnical properties of the core, including the loading from the planned Mid-Barataria sediment diversion which is expected to dramatically change the coastal landscape in this region.

  18. Correlation chart of Pennsylvanian rocks in Alabama, Tennessee, Kentucky, Virginia, West Virginia, Ohio, Maryland, and Pennsylvania showing approximate position of coal beds, coal zones, and key stratigraphic units

    USGS Publications Warehouse

    Ruppert, Leslie F.; Trippi, Michael H.; Slucher, Ernie R.

    2010-01-01

    This report contains a simplified provisional correlation chart that was compiled from both published and unpublished data in order to fill a need to visualize the currently accepted stratigraphic relations between Appalachian basin formations, coal beds and coal zones, and key stratigraphic units in the northern, central, and southern Appalachian basin coal regions of Alabama, Tennessee, Kentucky, Virginia, West Virginia, Ohio, Maryland, and Pennsylvania. Appalachian basin coal beds and coal zones were deposited in a variety of geologic settings throughout the Lower, Middle, and Upper Pennsylvanian and Pennsylvanian formations were defined on the presence or absence of economic coal beds and coarse-grained sandstones that often are local or regionally discontinuous. The correlation chart illustrates how stratigraphic units (especially coal beds and coal zones) and their boundaries can differ between States and regions.

  19. On the virtues of automated quantitative structure-activity relationship: the new kid on the block.

    PubMed

    de Oliveira, Marcelo T; Katekawa, Edson

    2018-02-01

    Quantitative structure-activity relationship (QSAR) has proved to be an invaluable tool in medicinal chemistry. Data availability at unprecedented levels through various databases have collaborated to a resurgence in the interest for QSAR. In this context, rapid generation of quality predictive models is highly desirable for hit identification and lead optimization. We showcase the application of an automated QSAR approach, which randomly selects multiple training/test sets and utilizes machine-learning algorithms to generate predictive models. Results demonstrate that AutoQSAR produces models of improved or similar quality to those generated by practitioners in the field but in just a fraction of the time. Despite the potential of the concept to the benefit of the community, the AutoQSAR opportunity has been largely undervalued.

  20. Classical seismic sequence stratigraphic interpretation of intraslope basin fill: Deepwater Nigeria

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duncan, E.A.

    Detailed interpretation of seismic facies patterns performed within the workstation environment provides an observation based methodology for constructing depositional models of turbidite and other reservoir bearing systems expected in deepwater Nigeria. The increased fidelity of the workstation allows greater detail and accuracy to be imposed onto depositional model construction by vastly improving the discrimination of depositional from structural seismic reflection geometries. In deepwater Nigeria interslope basins, depositional cyclicity is clearly indicated by vertical seismic facies successions in the same way as can be recognized in bed thickness trends from outcrop or well log data. The recognition of the seismic faciesmore » successions appears to break the stratigraphy into at least fourth and fifth order scale sequences. Highly {open_quotes}zoomed{close_quotes} instantaneous phase displays enhance the reflection character so that near outcrop scale (resolution less than 50 mters) interpretations of depositional facies can be made. Common seismic facies and geologic interpretation include: (1) low angle erosional surfaces as channel scour or mass wasting detachment; (2) low relief mounds, often in compensation cycle overlapping stacks reflecting compacted channelbelt fill; (3) unidirectional, low angle clinoform sets suggesting laterial accretion within a channel belt or possible contourite mounds; (4) abrupt, shingled blocks illustrating tilted fault blocks of small scale intraformation slumping; and (5) high reflection amplitude and continuous, parallel reflections of pelagic and hemipelagic condensed sections. There are other subtle seismic facies resolvable given the incraesed fidelity of the workstation interpretation. Mapping and translation of these geometries into more robust stratigraphic predictions should have positive impact on exploration and development success.« less

  1. Automated building of organometallic complexes from 3D fragments.

    PubMed

    Foscato, Marco; Venkatraman, Vishwesh; Occhipinti, Giovanni; Alsberg, Bjørn K; Jensen, Vidar R

    2014-07-28

    A method for the automated construction of three-dimensional (3D) molecular models of organometallic species in design studies is described. Molecular structure fragments derived from crystallographic structures and accurate molecular-level calculations are used as 3D building blocks in the construction of multiple molecular models of analogous compounds. The method allows for precise control of stereochemistry and geometrical features that may otherwise be very challenging, or even impossible, to achieve with commonly available generators of 3D chemical structures. The new method was tested in the construction of three sets of active or metastable organometallic species of catalytic reactions in the homogeneous phase. The performance of the method was compared with those of commonly available methods for automated generation of 3D models, demonstrating higher accuracy of the prepared 3D models in general, and, in particular, a much wider range with respect to the kind of chemical structures that can be built automatically, with capabilities far beyond standard organic and main-group chemistry.

  2. Impact of Automation on Technical Services.

    ERIC Educational Resources Information Center

    Rooks, Dana C.; Thompson, Linda L.

    1988-01-01

    Discusses the impact of automation on library technical services, and the need for library managers to be aware of the issues involved and to plan for future developments. The discussion focuses on the areas of job related concerns of technical staff, organizational structures, recruitment and training, and ergonomic considerations. (CLB)

  3. Evaluation of stratigraphic relations of sandstone-producing reservoirs in upper Council Grove and Chase groups (Permian) in north-central Oklahoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chaplin, J.R.

    1989-08-01

    Poor well control and the absence of surface stratigraphic control made previous interpretations of the stratigraphic relations of sandstone-producing reservoirs tenuous. Recent extensive analyses of surface outcrops and well and core data support the contention that the major sandstone-producing reservoirs can be physically correlated with formations in the outcrop section. Sandstone bodies within the upper Council Grove Group include Neva sand and Blackwell sand (Neva Limestone), Hotson-Kisner sand (Eskridge Shale), and the Whitney-Hodges sand. The Whitney-Hodges sand correlates, in part, with the Speiser Shale (Garrison Formation) of the outcrop section. However, previous usage suggested tentative correlations with sandstone bodies stratigraphicallymore » lower in the section. These sands were probably deposited in channels that were, in part, fluvial, tidal, or estuarine. Production from the Chase Group occurs locally within channelform sandstone bodies referred to as the Hoy-Matfield sand. These sands appear to be equivalent, occupying essentially the position of the Kinney Limestone Member (Matfield Shale) of the outcrop section. Detailed core-hole data at and in the vicinity of Kaw Dam, southeastern Kay County, and outcrops along the shoreline of Kaw Lake at Kaw City, Kay County, clearly demonstrate the facies distribution of the Hoy sand. Core-hole data has also delineated additional potential sandstone reservoirs within and near or at the top of the Fort Riley Limestone Member (Barneston Limestone). The Wolfe sand, a producing sandstone locally, occupies a stratigraphic position within the Doyle Shale.« less

  4. Methods for automated semantic definition of manufacturing structures (mBOM) in mechanical engineering companies

    NASA Astrophysics Data System (ADS)

    Stekolschik, Alexander, Prof.

    2017-10-01

    The bill of materials (BOM), which involves all parts and assemblies of the product, is the core of any mechanical or electronic product. The flexible and integrated management of engineering (Engineering Bill of Materials [eBOM]) and manufacturing (Manufacturing Bill of Materials [mBOM]) structures is the key to the creation of modern products in mechanical engineering companies. This paper presents a method framework for the creation and control of e- and, especially, mBOM. The requirements, resulting from the process of differentiation between companies that produce serialized or engineered-to-order products, are considered in the analysis phase. The main part of the paper describes different approaches to fully or partly automated creation of mBOM. The first approach is the definition of part selection rules in the generic mBOM templates. The mBOM can be derived from the eBOM for partly standardized products by using this method. Another approach is the simultaneous use of semantic rules, options, and parameters in both structures. The implementation of the method framework (selection of use cases) in a standard product lifecycle management (PLM) system is part of the research.

  5. Containerless automated processing of intermetallic compounds and composites

    NASA Technical Reports Server (NTRS)

    Johnson, D. R.; Joslin, S. M.; Reviere, R. D.; Oliver, B. F.; Noebe, R. D.

    1993-01-01

    An automated containerless processing system has been developed to directionally solidify high temperature materials, intermetallic compounds, and intermetallic/metallic composites. The system incorporates a wide range of ultra-high purity chemical processing conditions. The utilization of image processing for automated control negates the need for temperature measurements for process control. The list of recent systems that have been processed includes Cr, Mo, Mn, Nb, Ni, Ti, V, and Zr containing aluminides. Possible uses of the system, process control approaches, and properties and structures of recently processed intermetallics are reviewed.

  6. Automated Structure Annotation and Curation for MassBank: Potential and Pitfalls

    EPA Science Inventory

    The European MassBank server (www.massbank.eu) was founded in 2012 by the NORMAN Network (www.norman-network.net) to provide open access to mass spectra of substances of environmental interest contributed by NORMAN members. The automated workflow RMassBank was developed as a part...

  7. Stratigraphic record of the Yellowstone hotspot track, Neogene Sixmile Creek Formation grabens, southwest Montana

    NASA Astrophysics Data System (ADS)

    Sears, James W.; Hendrix, Marc S.; Thomas, Robert C.; Fritz, William J.

    2009-11-01

    The Sixmile Creek Formation fills deep grabens in southwest Montana and preserves a stratigraphic record of the evolution of the Yellowstone hotspot track from ~ 17 Ma to ~ 2 Ma. The Ruby, Beaverhead, Big Hole, Deer Lodge, Medicine Lodge-Grasshopper, Three Forks, Canyon Ferry, Jefferson, Melrose, Wise River, and Paradise grabens were active during outbreak of the hotspot. They appear to be parts of a radial system of extensional structures that may have formed on a broad dome that was centered on the hotspot outbreak area in southwest Idaho and southeast Oregon. Early in the evolution of the grabens, massive debris flows surged down Paleogene paleovalleys from uplifted and tilted horst blocks and accumulated in the grabens. The grabens captured runoff from the hotspot dome with thick deposits of river gravel that appear to have been derived, in part, from east-central Idaho. As the hotspot track propagated along the eastern Snake River Plain, silicic ash fell into the graben drainage basins and was reworked into thick fluvial beds along graben axes. The grabens were cross-cut by northwest-trending late Neogene grabens that propagated on the flanks of silicic volcanic centers along the hotspot track. The late Neogene grabens diverted the Middle Miocene drainage patterns in southwest Montana.

  8. High-resolution stratigraphic analyses of Permian-Triassic core material recovered in central Spitsbergen

    NASA Astrophysics Data System (ADS)

    Sleveland, Arve; Planke, Sverre; Zuchuat, Valentin; Franeck, Franziska; Svensen, Henrik; Midtkandal, Ivar; Hammer, Øyvind; Twitchett, Richard; Deltadalen Study Group

    2017-04-01

    The Siberian Traps voluminous igneous activity is considered a likely trigger for the Permian-Triassic global extinction event. However, documented evidence of the Siberian Traps environmental effects decreases away from the centre of volcanic activity in north-central Russia. Previous research on the Permian-Triassic boundary (PTB) mostly relies on field observations, and resolution has thus depended on outcrop quality. This study reports on two 90 m cored sedimentary successions intersecting the PTB in Deltadalen, Svalbard, providing high-quality material to a comprehensive documentation of the stratigraphic interval. Sequence stratigraphic concepts are utilised to help constrain the Permian-Triassic basin development models in Svalbard and the high-Arctic region. The cored sections are calibrated with outcrop data from near the drill site. One core has been systematically described and scanned using 500-μm and 200-μm resolution XRF, hyperspectral imagery and microfocus CT (latter only on selected core sections). The base of both cores represents the upper 15 m of the Permian Kapp Starostin Formation, which is dominated by green glauconitic sandstones with spiculitic cherts, and exhibit various degrees of bioturbation. The Kapp Starostin Formation is in turn sharply overlain by 2 m of heavily reworked sand- and mudstones, extensively bioturbated, representing the base of the lower Triassic Vikinghøgda Formation. These bioturbated units are conformably overlain by 9 m of ash-bearing laminated black shale where signs of biological activity both on micro- and macro-scale are limited, and is thus interpreted to have recorded the Permian-Triassic extinction interval. Descriptive sedimentology and sequence stratigraphic concepts reveal the onset of relative sea level rise at the Vikinghøgda Formation base. The disappearance of bioturbation and extensive presence of pyrite in the overlying laminated black shale of the Vikinghøgda Formation suggest near anoxic

  9. Study of Automated Module Fabrication for Lightweight Solar Blanket Utilization

    NASA Technical Reports Server (NTRS)

    Gibson, C. E.

    1979-01-01

    Cost-effective automated techniques for accomplishing the titled purpose; based on existing in-house capability are described. As a measure of the considered automation, the production of a 50 kilowatt solar array blanket, exclusive of support and deployment structure, within an eight-month fabrication period was used. Solar cells considered for this blanket were 2 x 4 x .02 cm wrap-around cells, 2 x 2 x .005 cm and 3 x 3 x .005 cm standard bar contact thin cells, all welded contacts. Existing fabrication processes are described, the rationale for each process is discussed, and the capability for further automation is discussed.

  10. ORIGAMI Automator Primer. Automated ORIGEN Source Terms and Spent Fuel Storage Pool Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wieselquist, William A.; Thompson, Adam B.; Bowman, Stephen M.

    2016-04-01

    Source terms and spent nuclear fuel (SNF) storage pool decay heat load analyses for operating nuclear power plants require a large number of Oak Ridge Isotope Generation and Depletion (ORIGEN) calculations. SNF source term calculations also require a significant amount of bookkeeping to track quantities such as core and assembly operating histories, spent fuel pool (SFP) residence times, heavy metal masses, and enrichments. The ORIGEN Assembly Isotopics (ORIGAMI) module in the SCALE code system provides a simple scheme for entering these data. However, given the large scope of the analysis, extensive scripting is necessary to convert formats and process datamore » to create thousands of ORIGAMI input files (one per assembly) and to process the results into formats readily usable by follow-on analysis tools. This primer describes a project within the SCALE Fulcrum graphical user interface (GUI) called ORIGAMI Automator that was developed to automate the scripting and bookkeeping in large-scale source term analyses. The ORIGAMI Automator enables the analyst to (1) easily create, view, and edit the reactor site and assembly information, (2) automatically create and run ORIGAMI inputs, and (3) analyze the results from ORIGAMI. ORIGAMI Automator uses the standard ORIGEN binary concentrations files produced by ORIGAMI, with concentrations available at all time points in each assembly’s life. The GUI plots results such as mass, concentration, activity, and decay heat using a powerful new ORIGEN Post-Processing Utility for SCALE (OPUS) GUI component. This document includes a description and user guide for the GUI, a step-by-step tutorial for a simplified scenario, and appendices that document the file structures used.« less

  11. 78 FR 66039 - Modification of National Customs Automation Program Test Concerning Automated Commercial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Customs Automation Program Test Concerning Automated Commercial Environment (ACE) Cargo Release (Formerly... Simplified Entry functionality in the Automated Commercial Environment (ACE). Originally, the test was known...) test concerning Automated Commercial Environment (ACE) Simplified Entry (SE test) functionality is...

  12. The logic of automated glycan assembly.

    PubMed

    Seeberger, Peter H

    2015-05-19

    Carbohydrates are the most abundant biopolymers on earth and part of every living creature. Glycans are essential as materials for nutrition and for information transfer in biological processes. To date, in few cases a detailed correlation between glycan structure and glycan function has been established. A molecular understanding of glycan function will require pure glycans for biological, immunological, and structural studies. Given the immense structural complexity of glycans found in living organisms and the lack of amplification methods or expression systems, chemical synthesis is the only means to access usable quantities of pure glycan molecules. While the solid-phase synthesis of DNA and peptides has become routine for decades, access to glycans has been technically difficult, time-consuming and confined to a few expert laboratories. In this Account, the development of a comprehensive approach to the automated synthesis of all classes of mammalian glycans, including glycosaminoglycans and glycosylphosphatidyl inositol (GPI) anchors, as well as bacterial and plant carbohydrates is described. A conceptual advance concerning the logic of glycan assembly was required in order to enable automated execution of the synthetic process. Based on the central glycosidic bond forming reaction, a general concept for the protecting groups and leaving groups has been developed. Building blocks that can be procured on large scale, are stable for prolonged periods of time, but upon activation result in high yields and selectivities were identified. A coupling-capping and deprotection cycle was invented that can be executed by an automated synthesis instrument. Straightforward postsynthetic protocols for cleavage from the solid support as well as purification of conjugation-ready oligosaccharides have been established. Introduction of methods to install selectively a wide variety of glycosidic linkages has enabled the rapid assembly of linear and branched oligo- and

  13. The stratigraphic record of Khawr Al Maqta, Abu Dhabi, United Arab Emirates

    NASA Astrophysics Data System (ADS)

    Lokier, S. W.; Herrmann, S.

    2012-04-01

    the stratigraphic sequence thereby resulting in a significant enhancement in porosity in the carbonate lithologies. This pervasive mouldic porosity is locally occluded by the precipitation of gypsum cements. The displacive precipitation of significant quantities of gypsum has resulted in the deformation of primary sedimentary structures. This complex sequence of mixed carbonate-siliciclastic-evaporite lithofacies is interpreted to record repeated episodes of flooding and sub-aerial exposure associated with the waxing and waning of the Pleistocene ice-sheets. During periods of relative sea-level fall carbonate sequences entered the meteoric realm with the consequent dissolution of unstable bioclasts. Transgression and reflooding once again isolated Abu Dhabi Island from the mainland, thus permitting the precipitation of shallow-water carbonate lithofacies. During sea-level highstands the north-westerly Shamal wind transported carbonate sediments into the lee-of the island resulting in the south-easterly shore-wards development of a tombolo. However, the strong tidal currents of the Khawr Al Maqta prevented final connection to the mainland, thus ensuring the isolation of Abu Dhabi until the subsequent regression.

  14. Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.

    PubMed

    Brunger, Axel T; Das, Debanu; Deacon, Ashley M; Grant, Joanna; Terwilliger, Thomas C; Read, Randy J; Adams, Paul D; Levitt, Michael; Schröder, Gunnar F

    2012-04-01

    Phasing by molecular replacement remains difficult for targets that are far from the search model or in situations where the crystal diffracts only weakly or to low resolution. Here, the process of determining and refining the structure of Cgl1109, a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum, at ∼3 Å resolution is described using a combination of homology modeling with MODELLER, molecular-replacement phasing with Phaser, deformable elastic network (DEN) refinement and automated model building using AutoBuild in a semi-automated fashion, followed by final refinement cycles with phenix.refine and Coot. This difficult molecular-replacement case illustrates the power of including DEN restraints derived from a starting model to guide the movements of the model during refinement. The resulting improved model phases provide better starting points for automated model building and produce more significant difference peaks in anomalous difference Fourier maps to locate anomalous scatterers than does standard refinement. This example also illustrates a current limitation of automated procedures that require manual adjustment of local sequence misalignments between the homology model and the target sequence.

  15. Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum

    PubMed Central

    Brunger, Axel T.; Das, Debanu; Deacon, Ashley M.; Grant, Joanna; Terwilliger, Thomas C.; Read, Randy J.; Adams, Paul D.; Levitt, Michael; Schröder, Gunnar F.

    2012-01-01

    Phasing by molecular replacement remains difficult for targets that are far from the search model or in situations where the crystal diffracts only weakly or to low resolution. Here, the process of determining and refining the structure of Cgl1109, a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum, at ∼3 Å resolution is described using a combination of homology modeling with MODELLER, molecular-replacement phasing with Phaser, deformable elastic network (DEN) refinement and automated model building using AutoBuild in a semi-automated fashion, followed by final refinement cycles with phenix.refine and Coot. This difficult molecular-replacement case illustrates the power of including DEN restraints derived from a starting model to guide the movements of the model during refinement. The resulting improved model phases provide better starting points for automated model building and produce more significant difference peaks in anomalous difference Fourier maps to locate anomalous scatterers than does standard refinement. This example also illustrates a current limitation of automated procedures that require manual adjustment of local sequence misalignments between the homology model and the target sequence. PMID:22505259

  16. Role of home automation in distribution automation and automated meter reading. Tropical report, December 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, K.W.

    1994-12-01

    This is one of a series of topical reports dealing with the strategic, technical, and market development of home automation. Particular emphasis is placed upon identifying those aspects of home automation that will impact the gas industry and gas products. Communication standards, market drivers, key organizations, technical implementation, product opportunities, and market growth projects will all be addressed in this or subsequent reports. These reports will also discuss how the gas industry and gas-fired equipment can use home automation technology to benefit the consumer.

  17. Automated Sample Exchange Robots for the Structural Biology Beam Lines at the Photon Factory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hiraki, Masahiko; Watanabe, Shokei; Yamada, Yusuke

    2007-01-19

    We are now developing automated sample exchange robots for high-throughput protein crystallographic experiments for onsite use at synchrotron beam lines. It is part of the fully automated robotics systems being developed at the Photon Factory, for the purposes of protein crystallization, monitoring crystal growth, harvesting and freezing crystals, mounting the crystals inside a hutch and for data collection. We have already installed the sample exchange robots based on the SSRL automated mounting system at our insertion device beam lines BL-5A and AR-NW12A at the Photon Factory. In order to reduce the time required for sample exchange further, a prototype ofmore » a double-tonged system was developed. As a result of preliminary experiments with double-tonged robots, the sample exchange time was successfully reduced from 70 seconds to 10 seconds with the exception of the time required for pre-cooling and warming up the tongs.« less

  18. A new stratigraphic model for the deposition of the Dammam Formation

    NASA Astrophysics Data System (ADS)

    Lokier, Stephen; Fiorini, Flavia; Min, Jina

    2017-04-01

    In recent years, mixed siliciclastic-carbonate successions have increasingly become targets for hydrocarbon exploration and production activities. Despite the abundance of these successions throughout the Middle East, there have been very few attempts to employ quantitative techniques to interpret their depositional settings and to develop constrained sequence stratigraphic models for their deposition. This study focuses on the Eocene age Dammam Formation that crops out on the flanks of the Jebel Hafeet anticline south of Al Ain in the United Arab Emirates. The Dammam Formation comprises units alternating between poorly-lithified, easily-weathered, siliciclastic and marly horizons and well-lithified limestones. These units were deposited in a foreland basin that formed in association with the Late Cretaceous obduction of the Semail Ophiolite onto the northeastern margin of the Arabian Plate. The Paleogene infilling of this basin is recorded in the shallowing-upward sedimentary sequence of the lithologies of the Pabdeh Group. This succession records the transition from marine carbonate sedimentation, through increasingly evaporitic-dominated units during the late Eocene to early Miocene to a fluvial-alluvial system by mid to late Miocene times. The Dammam Formation was deposited in an open shallow-marine setting strongly influenced by the influx of siliciclastic material sourced from the close-by uplifted massif of the obducted ophiolite. The skeletal assemblage of the Dammam Formation is dominated by Nummulites and Assilina larger benthic foraminifera along with subordinate smaller foraminifera, echinoids, bivalves, corals, bryozoan, gastropods, echinoids and calcareous algae. Previous studies of the Dammam Formation have employed the biotic component in the reconstruction of water depth. However, these studies neglected to consider that turbidity, associated with the abundant siliciclastic component, resulted in a reduction in the depth of the euphotic zone and a

  19. 3D stratigraphic forward modelling of Shu'aiba Platform stratigraphy in the Bu Hasa Field, Abu Dhabi, United Arab Emirates.

    NASA Astrophysics Data System (ADS)

    Hu, J.; Lokier, S. W.

    2012-04-01

    This paper presents the results of three dimensional sequence stratigraphic forward modelling of the Aptian age Shu'aiba Formation from Abu Dhabi, United Arab Emirates (UAE). The Shu'aiba Formation lies within the uppermost part of the Lower Cretaceous Thamama Group and forms one of the most prolific hydrocarbon reservoir intervals of the Middle East with production dating back to the 1960's. The Shu'aiba Formation developed as a series of laterally-extensive shallow-water carbonate platforms in an epeiric sea that extended over the northern margin of the African-Arabian Plate. This shallow sea was bounded by the Arabian Shield to the west and the passive margin with the Neo-Tethys Ocean towards the north and east (Droste, 2010). The exposed Arabian Shield acted as a source of siliciclastic sediments to westernmost regions, however, more offshore areas were dominated by shallow-water carbonate deposition. Carbonate production was variously dominated by Lithocodium-Baccinella, orbitolinid foraminifera and rudist bivalves depending on local conditions. While there have been numerous studies of this important stratigraphic interval (for examples see van Buchem et al., 2010), there has been little attempt to simulate the sequence stratigraphic development of the formation. During the present study modelling was undertaken utilising the CARBONATE-3D stratigraphic forward modelling software (Warrlich et al., 2008; Warrlich et al., 2002)) thus allowing for the control of a diverse range of internal and external parameters on carbonate sequence development. This study focuses on platform development in the onshore Bu Hasa Field - the first giant oilfield to produce from the Shu'aiba Formation in Abu Dhabi. The carbonates of the Bu Hasa field were deposited on the southwest slope of the intra-shelf Bab Basin, siliciclastic content is minor. Initially these carbonates were algal dominated with rudist mounds becoming increasingly important over time (Alsharhan, 1987

  20. Neogene and Quaternary geology of a stratigraphic test hole on Horn Island, Mississippi Sound

    USGS Publications Warehouse

    Gohn, Gregory S.; Brewster-Wingard, G. Lynn; Cronin, Thomas M.; Edwards, Lucy E.; Gibson, Thomas G.; Rubin, Meyer; Willard, Debra A.

    1996-01-01

    During April and May, 1991, the U.S. Geological Survey (USGS) drilled a 510-ft-deep, continuously cored, stratigraphic test hole on Horn Island, Mississippi Sound, as part of a field study of the Neogene and Quaternary geology of the Mississippi coastal area. The USGS drilled two new holes at the Horn Island site. The first hole was continuously cored to a depth of 510 ft; coring stopped at this depth due to mechanical problems. To facilitate geophysical logging, an unsampled second hole was drilled to a depth of 519 ft at the same location.

  1. Automated mesostructural analyses using GIS, Beta test: Paleozoic structures from the New Jersey Great Valley region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herman, G.C.; French, M.A.; Monteverde, D.H.

    1993-03-01

    An automated method has been developed for representing outcrop data on geologic structures on maps. Using a MS-DOS custom database management system in conjunction with the ARC/INFO Geographic Information System (GIS), trends of geologic structures are plotted with user-specific symbols. The length of structural symbols can be frequency-weighted based on collective values from structural domains. The PC-based data manager is the NJGS Field data Management System (FMS) Version 2.0 which includes sort, output, and analysis functions for structural data input in either azimuth or quadrant form. Program options include lineament sorting, data output to other data management and analysis software,more » and a circular histogram (rose diagram) routine for trend frequency analysis. Trends can be displayed with either half-or full-rose diagrams using either 10[degree] sectors or one degree spikes for strike, trend, or dip azimuth readings. Scalar and vector statistics are both included. For the mesostructural analysis, ASCII files containing the station number, structural trend and inclination, and plot-symbol-length value are downloaded from FMS and uploaded into an ARC/INFO macro which sequentially plots the information. Plots can be generated in conjunction with any complimentary GIS coverage for various types of spatial analyses. Mesostructural plots can be used for regional tectonic analyses, for hydrogeologic analysis of fractured bedrock aquifers, or for ground-truthing data from fracture-trace or lineament analyses.« less

  2. Palaeobiology, palaeoecology and stratigraphic significance of the Late Miocene cockle Lymnocardium soproniense from Lake Pannon

    NASA Astrophysics Data System (ADS)

    Magyar, Imre; Cziczer, István; Sztanó, Orsolya; Dávid, Árpád; Johnson, Michael

    2016-12-01

    Stratigraphic subdivision of the Upper Miocene deposits in the Pannonian Basin has been traditionally based on the endemic mollusc species of Lake Pannon. The cockle species Lymnocardium soproniense Vitális, apparently evolving through a sympatric speciation event in the sublittoral zone of Lake Pannon about 10.2-10.3 Ma, attained wide geographical distribution in the Pannonian basin and thus may serve as a good stratigraphic marker. Lymnocardium soproniense was one of the few large-sized cockles in Lake Pannon, most closely related to its ancestor, L. schedelianum (Fuchs), and to another descendant of the latter, L. variocostatum Vitális. According to the δ18O stable isotope record of its shells, the large size of L. soproniense was coupled with an extended life time of more than 10 years, probably reflecting a stable lake environment with increased resource availability and decreased predation. The species lived in quiet offshore conditions, below the storm wave base, where clay was deposited from suspension and the influence of currents was negligible. The base of the Lymnocardium soproniense Zone in the sublittoral deposits of Lake Pannon is defined by the first occurrence of the species, whereas the top of the zone is marked with the base of the overlying Congeria praerhomboidea Zone, defined by the FAD of C. praerhomboidea.

  3. The Daptocephalus Assemblage Zone (Lopingian), South Africa: A proposed biostratigraphy based on a new compilation of stratigraphic ranges

    NASA Astrophysics Data System (ADS)

    Viglietti, Pia A.; Smith, Roger M. H.; Angielczyk, Kenneth D.; Kammerer, Christian F.; Fröbisch, Jörg; Rubidge, Bruce S.

    2016-01-01

    The Dicynodon Assemblage Zone (DiAZ) of South Africa's Karoo Basin is one of the eight biostratigraphic zones of the Beaufort Group. It spans the uppermost Permian strata (Balfour, Teekloof, and Normandien formations) and traditionally has been considered to terminate with the disappearance of Dicynodon lacerticeps at the Permo-Triassic Boundary. We demonstrate that the three index fossils currently used to define the Dicynodon Assemblage Zone (Dicynodon lacerticeps, Theriognathus microps, and Procynosuchus delaharpeae) have first appearance datums (FADs) below its traditionally recognized lower boundary and have ranges mostly restricted to the lower portion of the biozone, well below the Permo-Triassic Boundary. We propose re-establishing Daptocephalus leoniceps as an index fossil for this stratigraphic interval, and reinstating the name Daptocephalus Assemblage Zone (DaAZ) for this unit. Furthermore, the FAD of Lystrosaurus maccaigi in the uppermost reaches of the biozone calls for the establishment of a two-fold subdivision of the current Dicynodon Assemblage Zone. The biostratigraphic utility of Da. leoniceps and other South African dicynodontoids outside of the Karoo Basin is limited due to basinal endemism at the species level and varying temporal ranges of dicynodontoids globally. Therefore, we recommend their use only for correlation within the Karoo Basin at this time. Revision of the stratigraphic ranges of all late Permian tetrapods does not reveal a significant change in faunal diversity between the lower and upper DaAZ. However, the last appearance datums of the abundant taxa Di. lacerticeps, T. microps, P. delaharpeae, and Diictodon feliceps occur below the three extinction phases associated with the end-Permian mass extinction event. Due to northward attenuation of the strata, however, the stratigraphic position of the extinction phases may need to be reconsidered.

  4. The Antiquity of the Rhine River: Stratigraphic Coverage of the Dinotheriensande (Eppelsheim Formation) of the Mainz Basin (Germany)

    PubMed Central

    Böhme, Madelaine; Aiglstorfer, Manuela; Uhl, Dieter; Kullmer, Ottmar

    2012-01-01

    Background Mammalian fossils from the Eppelsheim Formation (Dinotheriensande) have been a benchmark for Neogene vertebrate palaeontology since 200 years. Worldwide famous sites like Eppelsheim serve as key localities for biochronologic, palaeobiologic, environmental, and mammal community studies. So far the formation is considered to be of early Late Miocene age (∼9.5 Ma, Vallesian), representing the oldest sediments of the Rhine River. The stratigraphic unity of the formation and of its fossil content was disputed at times, but persists unresolved. Principal Findings Here we investigate a new fossil sample from Sprendlingen, composed by over 300 mammalian specimens and silicified wood. The mammals comprise entirely Middle Miocene species, like cervids Dicrocerus elegans, Paradicrocerus elegantulus, and deinotheres Deinotherium bavaricum and D. levius. A stratigraphic evaluation of Miocene Central European deer and deinothere species proof the stratigraphic inhomogenity of the sample, and suggest late Middle Miocene (∼12.5 Ma) reworking of early Middle Miocene (∼15 Ma) sediments. This results agree with taxonomic and palaeoclimatic analysis of plant fossils from above and within the mammalian assemblage. Based on the new fossil sample and published data three biochronologic levels within the Dinotheriensand fauna can be differentiated, corresponding to early Middle Miocene (late Orleanian to early Astaracian), late Middle Miocene (late Astaracian), and early Late Miocene (Vallesian) ages. Conclusions/Significance This study documents complex faunal mixing of classical Dinotheriensand fauna, covering at least six million years, during a time of low subsidence in the Mainz Basin and shifts back the origination of the Rhine River by some five million years. Our results have severe implications for biostratigraphy and palaeobiology of the Middle to Late Miocene. They suggest that turnover events may be obliterated and challenge the proposed

  5. Keep Your Scanners Peeled: Gaze Behavior as a Measure of Automation Trust During Highly Automated Driving.

    PubMed

    Hergeth, Sebastian; Lorenz, Lutz; Vilimek, Roman; Krems, Josef F

    2016-05-01

    The feasibility of measuring drivers' automation trust via gaze behavior during highly automated driving was assessed with eye tracking and validated with self-reported automation trust in a driving simulator study. Earlier research from other domains indicates that drivers' automation trust might be inferred from gaze behavior, such as monitoring frequency. The gaze behavior and self-reported automation trust of 35 participants attending to a visually demanding non-driving-related task (NDRT) during highly automated driving was evaluated. The relationship between dispositional, situational, and learned automation trust with gaze behavior was compared. Overall, there was a consistent relationship between drivers' automation trust and gaze behavior. Participants reporting higher automation trust tended to monitor the automation less frequently. Further analyses revealed that higher automation trust was associated with lower monitoring frequency of the automation during NDRTs, and an increase in trust over the experimental session was connected with a decrease in monitoring frequency. We suggest that (a) the current results indicate a negative relationship between drivers' self-reported automation trust and monitoring frequency, (b) gaze behavior provides a more direct measure of automation trust than other behavioral measures, and (c) with further refinement, drivers' automation trust during highly automated driving might be inferred from gaze behavior. Potential applications of this research include the estimation of drivers' automation trust and reliance during highly automated driving. © 2016, Human Factors and Ergonomics Society.

  6. Stratigraphic controls on saltwater intrusion in the Dominguez Gap area of coastal Los Angeles

    USGS Publications Warehouse

    Edwards, Brian D.; Ehman, Kenneth D.; Ponti, Daniel J.; Reichard, Eric G.; Tinsley, John; Rosenbauer, Robert J.; Land, Michael T.

    2009-01-01

    The Los Angeles Basin is a densely populated coastal area that significantly depends on groundwater. A part of this groundwater supply is at risk from saltwater intrusion-the impetus for this study. High-resolution seismic-reflection data collected from the Los Angeles-Long Beach Harbor Complex have been combined with borehole geophysical and descriptive geological data from four nearby ??400-m-deep continuously cored wells and with borehole geophysical data from adjacent water and oil wells to characterize the Pliocene to Holocene stratigraphy of the Dominguez Gap coastal aquifer system. The new data are shown as a north-south, two- dimensional, sequence-stratigraphic model that is compared to existing lithostratigraphic models of the Los Angeles Basin in an attempt to better understand pathways of saltwater intrusion into coastal aquifers. Intrusion of saltwater into the coastal aquifer system generally is attributed to over-pumping that caused the hydraulic gradient to reverse during the mid-1920s. Local water managers have used the existing lithostratigraphic model to site closely spaced injection wells of freshwater (barrier projects) attempting to hydraulically control the saltwater intrusion. Improved understanding of the stratigraphic relationships can guide modifications to barrier design that will allow more efficient operation. Allostratigraphic nomenclature is used to define a new sequence-stratigraphic model for the area because the existing lithostratigraphic correlations that have been used to define aquifer systems are shown not to be time-correlative. The youngest sequence, the Holocene Dominguez sequence, contains the Gaspur aquifer at its base. The Gaspur aquifer is intruded with saltwater and consists of essentially flat-lying gravelly sands deposited by the ancestral Los Angeles River as broad channels that occupied a paleovalley incised into the coastal plain during the last glacio-eustatic highstand. The underlying sequences are deformed into

  7. Automated RTOP Management System

    NASA Technical Reports Server (NTRS)

    Hayes, P.

    1984-01-01

    The structure of NASA's Office of Aeronautics and Space Technology electronic information system network from 1983 to 1985 is illustrated. The RTOP automated system takes advantage of existing hardware, software, and expertise, and provides: (1) computerized cover sheet and resources forms; (2) electronic signature and transmission; (3) a data-based information system; (4) graphics; (5) intercenter communications; (6) management information; and (7) text editing. The system is coordinated with Headquarters efforts in codes R,E, and T.

  8. Automated identification of cone photoreceptors in adaptive optics retinal images.

    PubMed

    Li, Kaccie Y; Roorda, Austin

    2007-05-01

    In making noninvasive measurements of the human cone mosaic, the task of labeling each individual cone is unavoidable. Manual labeling is a time-consuming process, setting the motivation for the development of an automated method. An automated algorithm for labeling cones in adaptive optics (AO) retinal images is implemented and tested on real data. The optical fiber properties of cones aided the design of the algorithm. Out of 2153 manually labeled cones from six different images, the automated method correctly identified 94.1% of them. The agreement between the automated and the manual labeling methods varied from 92.7% to 96.2% across the six images. Results between the two methods disagreed for 1.2% to 9.1% of the cones. Voronoi analysis of large montages of AO retinal images confirmed the general hexagonal-packing structure of retinal cones as well as the general cone density variability across portions of the retina. The consistency of our measurements demonstrates the reliability and practicality of having an automated solution to this problem.

  9. Bayesian automated cortical segmentation for neonatal MRI

    NASA Astrophysics Data System (ADS)

    Chou, Zane; Paquette, Natacha; Ganesh, Bhavana; Wang, Yalin; Ceschin, Rafael; Nelson, Marvin D.; Macyszyn, Luke; Gaonkar, Bilwaj; Panigrahy, Ashok; Lepore, Natasha

    2017-11-01

    Several attempts have been made in the past few years to develop and implement an automated segmentation of neonatal brain structural MRI. However, accurate automated MRI segmentation remains challenging in this population because of the low signal-to-noise ratio, large partial volume effects and inter-individual anatomical variability of the neonatal brain. In this paper, we propose a learning method for segmenting the whole brain cortical grey matter on neonatal T2-weighted images. We trained our algorithm using a neonatal dataset composed of 3 fullterm and 4 preterm infants scanned at term equivalent age. Our segmentation pipeline combines the FAST algorithm from the FSL library software and a Bayesian segmentation approach to create a threshold matrix that minimizes the error of mislabeling brain tissue types. Our method shows promising results with our pilot training set. In both preterm and full-term neonates, automated Bayesian segmentation generates a smoother and more consistent parcellation compared to FAST, while successfully removing the subcortical structure and cleaning the edges of the cortical grey matter. This method show promising refinement of the FAST segmentation by considerably reducing manual input and editing required from the user, and further improving reliability and processing time of neonatal MR images. Further improvement will include a larger dataset of training images acquired from different manufacturers.

  10. Integrating seismic-reflection and sequence-stratigraphic methods to characterize the hydrogeology of the Floridan aquifer system in southeast Florida

    USGS Publications Warehouse

    Cunningham, Kevin J.

    2013-01-01

    The Floridan aquifer system (FAS) is receiving increased attention as a result of regulatory restrictions on water-supply withdrawals and treated wastewater management practices. The South Florida Water Management District’s Regional Water Availability Rule, adopted in 2007, restricts urban withdrawals from the shallower Biscayne aquifer to pre-April 2006 levels throughout southeast Florida. Legislation adopted by the State of Florida requires elimination of ocean outfalls of treated wastewater by 2025. These restrictions have necessitated the use of the more deeply buried FAS as an alternate water resource to meet projected water-supply shortfalls, and as a repository for the disposal of wastewater via Class I deep injection wells and injection of reclaimed water. Some resource managers in Broward County have expressed concern regarding the viability of the FAS as an alternative water supply due to a lack of technical data and information regarding its long-term sustainability. Sustainable development and management of the FAS for water supply is uncertain because of the potential risk posed by structural geologic anomalies (faults, fractures, and karst collapse structures) and knowledge gaps in the stratigraphy of the system. The integration of seismic-reflection and borehole data into an improved geologic and hydrogeologic framework will provide a better understanding of the structural and stratigraphic features that influence groundwater flow and contaminant transport.

  11. Automated laser-based barely visible impact damage detection in honeycomb sandwich composite structures

    NASA Astrophysics Data System (ADS)

    Girolamo, D.; Girolamo, L.; Yuan, F. G.

    2015-03-01

    Nondestructive evaluation (NDE) for detection and quantification of damage in composite materials is fundamental in the assessment of the overall structural integrity of modern aerospace systems. Conventional NDE systems have been extensively used to detect the location and size of damages by propagating ultrasonic waves normal to the surface. However they usually require physical contact with the structure and are time consuming and labor intensive. An automated, contactless laser ultrasonic imaging system for barely visible impact damage (BVID) detection in advanced composite structures has been developed to overcome these limitations. Lamb waves are generated by a Q-switched Nd:YAG laser, raster scanned by a set of galvano-mirrors over the damaged area. The out-of-plane vibrations are measured through a laser Doppler Vibrometer (LDV) that is stationary at a point on the corner of the grid. The ultrasonic wave field of the scanned area is reconstructed in polar coordinates and analyzed for high resolution characterization of impact damage in the composite honeycomb panel. Two methodologies are used for ultrasonic wave-field analysis: scattered wave field analysis (SWA) and standing wave energy analysis (SWEA) in the frequency domain. The SWA is employed for processing the wave field and estimate spatially dependent wavenumber values, related to discontinuities in the structural domain. The SWEA algorithm extracts standing waves trapped within damaged areas and, by studying the spectrum of the standing wave field, returns high fidelity damage imaging. While the SWA can be used to locate the impact damage in the honeycomb panel, the SWEA produces damage images in good agreement with X-ray computed tomographic (X-ray CT) scans. The results obtained prove that the laser-based nondestructive system is an effective alternative to overcome limitations of conventional NDI technologies.

  12. An Automated Energy Detection Algorithm Based on Morphological Filter Processing with a Semi-Disk Structure

    DTIC Science & Technology

    2018-01-01

    statistical moments of order 2, 3, and 4. The probability density function (PDF) of the vibrational time series of a good bearing has a Gaussian...ARL-TR-8271 ● JAN 2018 US Army Research Laboratory An Automated Energy Detection Algorithm Based on Morphological Filter...when it is no longer needed. Do not return it to the originator. ARL-TR-8271 ● JAN 2018 US Army Research Laboratory An Automated

  13. An ultraviolet-visible spectrophotometer automation system. Part 3: Program documentation

    NASA Astrophysics Data System (ADS)

    Roth, G. S.; Teuschler, J. M.; Budde, W. L.

    1982-07-01

    The Ultraviolet-Visible Spectrophotometer (UVVIS) automation system accomplishes 'on-line' spectrophotometric quality assurance determinations, report generations, plot generations and data reduction for chlorophyll or color analysis. This system also has the capability to process manually entered data for the analysis of chlorophyll or color. For each program of the UVVIS system, this document contains a program description, flowchart, variable dictionary, code listing, and symbol cross-reference table. Also included are descriptions of file structures and of routines common to all automated analyses. The programs are written in Data General extended BASIC, Revision 4.3, under the RDOS operating systems, Revision 6.2. The BASIC code has been enhanced for real-time data acquisition, which is accomplished by CALLS to assembly language subroutines. Two other related publications are 'An Ultraviolet-Visible Spectrophotometer Automation System - Part I Functional Specifications,' and 'An Ultraviolet-Visible Spectrophotometer Automation System - Part II User's Guide.'

  14. Parmodel: a web server for automated comparative modeling of proteins.

    PubMed

    Uchôa, Hugo Brandão; Jorge, Guilherme Eberhart; Freitas Da Silveira, Nelson José; Camera, João Carlos; Canduri, Fernanda; De Azevedo, Walter Filgueira

    2004-12-24

    Parmodel is a web server for automated comparative modeling and evaluation of protein structures. The aim of this tool is to help inexperienced users to perform modeling, assessment, visualization, and optimization of protein models as well as crystallographers to evaluate structures solved experimentally. It is subdivided in four modules: Parmodel Modeling, Parmodel Assessment, Parmodel Visualization, and Parmodel Optimization. The main module is the Parmodel Modeling that allows the building of several models for a same protein in a reduced time, through the distribution of modeling processes on a Beowulf cluster. Parmodel automates and integrates the main softwares used in comparative modeling as MODELLER, Whatcheck, Procheck, Raster3D, Molscript, and Gromacs. This web server is freely accessible at .

  15. Process development for automated solar cell and module production. Task 4: Automated array assembly

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A process sequence which can be used in conjunction with automated equipment for the mass production of solar cell modules for terrestrial use was developed. The process sequence was then critically analyzed from a technical and economic standpoint to determine the technological readiness of certain process steps for implementation. The steps receiving analysis were: back contact metallization, automated cell array layup/interconnect, and module edge sealing. For automated layup/interconnect, both hard automation and programmable automation (using an industrial robot) were studied. The programmable automation system was then selected for actual hardware development.

  16. Management Planning for Workplace Automation.

    ERIC Educational Resources Information Center

    McDole, Thomas L.

    Several factors must be considered when implementing office automation. Included among these are whether or not to automate at all, the effects of automation on employees, requirements imposed by automation on the physical environment, effects of automation on the total organization, and effects on clientele. The reasons behind the success or…

  17. Tectono-stratigraphic evolution and crustal architecture of the Orphan Basin during North Atlantic rifting

    NASA Astrophysics Data System (ADS)

    Gouiza, Mohamed; Hall, Jeremy; Welford, J. Kim

    2017-04-01

    The Orphan Basin is located in the deep offshore of the Newfoundland margin, and it is bounded by the continental shelf to the west, the Grand Banks to the south, and the continental blocks of Orphan Knoll and Flemish Cap to the east. The Orphan Basin formed in Mesozoic time during the opening of the North Atlantic Ocean between eastern Canada and western Iberia-Europe. This work, based on well data and regional seismic reflection profiles across the basin, indicates that the continental crust was affected by several extensional episodes between the Jurassic and the Early Cretaceous, separated by events of uplift and erosion. The preserved tectono-stratigraphic sequences in the basin reveal that deformation initiated in the eastern part of the Orphan Basin in the Jurassic and spread towards the west in the Early Cretaceous, resulting in numerous rift structures filled with a Jurassic-Lower Cretaceous syn-rift succession and overlain by thick Upper Cretaceous to Cenozoic post-rift sediments. The seismic data show an extremely thinned crust (4-16 km thick) underneath the eastern and western parts of the Orphan Basin, forming two sub-basins separated by a wide structural high with a relatively thick crust (17 km thick). Quantifying the crustal architecture in the basin highlights the large discrepancy between brittle extension localized in the upper crust and the overall crustal thinning. This suggests that continental deformation in the Orphan Basin involved, in addition to the documented Jurassic and Early Cretaceous rifting, an earlier brittle rift phase which is unidentifiable in seismic data and a depth-dependent thinning of the crust driven by localized lower crust ductile flow.

  18. Fully automated segmentation of callus by micro-CT compared to biomechanics.

    PubMed

    Bissinger, Oliver; Götz, Carolin; Wolff, Klaus-Dietrich; Hapfelmeier, Alexander; Prodinger, Peter Michael; Tischer, Thomas

    2017-07-11

    A high percentage of closed femur fractures have slight comminution. Using micro-CT (μCT), multiple fragment segmentation is much more difficult than segmentation of unfractured or osteotomied bone. Manual or semi-automated segmentation has been performed to date. However, such segmentation is extremely laborious, time-consuming and error-prone. Our aim was to therefore apply a fully automated segmentation algorithm to determine μCT parameters and examine their association with biomechanics. The femura of 64 rats taken after randomised inhibitory or neutral medication, in terms of the effect on fracture healing, and controls were closed fractured after a Kirschner wire was inserted. After 21 days, μCT and biomechanical parameters were determined by a fully automated method and correlated (Pearson's correlation). The fully automated segmentation algorithm automatically detected bone and simultaneously separated cortical bone from callus without requiring ROI selection for each single bony structure. We found an association of structural callus parameters obtained by μCT to the biomechanical properties. However, results were only explicable by additionally considering the callus location. A large number of slightly comminuted fractures in combination with therapies that influence the callus qualitatively and/or quantitatively considerably affects the association between μCT and biomechanics. In the future, contrast-enhanced μCT imaging of the callus cartilage might provide more information to improve the non-destructive and non-invasive prediction of callus mechanical properties. As studies evaluating such important drugs increase, fully automated segmentation appears to be clinically important.

  19. Automated and assisted RNA resonance assignment using NMR chemical shift statistics

    PubMed Central

    Aeschbacher, Thomas; Schmidt, Elena; Blatter, Markus; Maris, Christophe; Duss, Olivier; Allain, Frédéric H.-T.; Güntert, Peter; Schubert, Mario

    2013-01-01

    The three-dimensional structure determination of RNAs by NMR spectroscopy relies on chemical shift assignment, which still constitutes a bottleneck. In order to develop more efficient assignment strategies, we analysed relationships between sequence and 1H and 13C chemical shifts. Statistics of resonances from regularly Watson–Crick base-paired RNA revealed highly characteristic chemical shift clusters. We developed two approaches using these statistics for chemical shift assignment of double-stranded RNA (dsRNA): a manual approach that yields starting points for resonance assignment and simplifies decision trees and an automated approach based on the recently introduced automated resonance assignment algorithm FLYA. Both strategies require only unlabeled RNAs and three 2D spectra for assigning the H2/C2, H5/C5, H6/C6, H8/C8 and H1′/C1′ chemical shifts. The manual approach proved to be efficient and robust when applied to the experimental data of RNAs with a size between 20 nt and 42 nt. The more advanced automated assignment approach was successfully applied to four stem-loop RNAs and a 42 nt siRNA, assigning 92–100% of the resonances from dsRNA regions correctly. This is the first automated approach for chemical shift assignment of non-exchangeable protons of RNA and their corresponding 13C resonances, which provides an important step toward automated structure determination of RNAs. PMID:23921634

  20. Automation in astronomy.

    NASA Technical Reports Server (NTRS)

    Wampler, E. J.

    1972-01-01

    Description and evaluation of the remotely operated Lick Observatory Cassegrain focus of the 120-inch telescope. The experience with this instrument has revealed that an automated system can profoundly change the observer's approach to his work. This makes it difficult to evaluate the 'advantage' of an automated telescope over a conventional instrument. Some of the problems arising with automation in astronomy are discussed.

  1. Neoproterozoic stratigraphic framework of the Tarim Craton in NW China: Implications for rift evolution

    NASA Astrophysics Data System (ADS)

    Wu, Lin; Guan, Shuwei; Zhang, Shuichang; Yang, Haijun; Jin, Jiuqiang; Zhang, Xiaodan; Zhang, Chunyu

    2018-06-01

    The Tarim Craton is overlain by thick Neoproterozoic sedimentary successions in rift tectonic setting. This study examines the latest outcrop, seismic, and drilling core data with the objective of investigating the regional stratigraphy to deeply recognize the evolution of rifting in the craton. Cryogenian to Lower Ediacaran successions are mainly composed of clastic rocks with thicknesses of 2000-3000 m, and the Upper Ediacaran successions are composed of carbonate rocks with thicknesses of 500-800 m. The rift basins and stratigraphic zones are divided into northern and southern parts by a central paleo-uplift. The northern rift basin extends through the northern Tarim Craton in an E-W direction with two depocenters (Aksu and Kuruktag). The southern rift basin is oriented NE-SW. There are three or four phases of tillites in the northern zone, while there are two in the southern zone. Given the north-south difference of the stratigraphic framework, the northern rift basin initiated at ca. 740 Ma and the southern rift basin initiated at ca. 780 Ma. During the Cryogenian and Ediacaran, the northern and southern rift basins were separated by the central paleo-uplift, finally connecting with each other in the early Cambrian. Tectonic deformation in the Late Ediacaran led to the formation of a parallel unconformity in the rift basins and an angular unconformity in the central paleo-uplift. The Neoproterozoic rift basins continued to affect the distribution of Lower Cambrian hydrocarbon source rocks. The north-south distribution and evolution of the rift basins in the Tarim Craton have implications for reconstructions of the Rodinia supercontinent.

  2. Large - scale Rectangular Ruler Automated Verification Device

    NASA Astrophysics Data System (ADS)

    Chen, Hao; Chang, Luping; Xing, Minjian; Xie, Xie

    2018-03-01

    This paper introduces a large-scale rectangular ruler automated verification device, which consists of photoelectric autocollimator and self-designed mechanical drive car and data automatic acquisition system. The design of mechanical structure part of the device refer to optical axis design, drive part, fixture device and wheel design. The design of control system of the device refer to hardware design and software design, and the hardware mainly uses singlechip system, and the software design is the process of the photoelectric autocollimator and the automatic data acquisition process. This devices can automated achieve vertical measurement data. The reliability of the device is verified by experimental comparison. The conclusion meets the requirement of the right angle test procedure.

  3. Automated Conflict Resolution For Air Traffic Control

    NASA Technical Reports Server (NTRS)

    Erzberger, Heinz

    2005-01-01

    The ability to detect and resolve conflicts automatically is considered to be an essential requirement for the next generation air traffic control system. While systems for automated conflict detection have been used operationally by controllers for more than 20 years, automated resolution systems have so far not reached the level of maturity required for operational deployment. Analytical models and algorithms for automated resolution have been traffic conditions to demonstrate that they can handle the complete spectrum of conflict situations encountered in actual operations. The resolution algorithm described in this paper was formulated to meet the performance requirements of the Automated Airspace Concept (AAC). The AAC, which was described in a recent paper [1], is a candidate for the next generation air traffic control system. The AAC's performance objectives are to increase safety and airspace capacity and to accommodate user preferences in flight operations to the greatest extent possible. In the AAC, resolution trajectories are generated by an automation system on the ground and sent to the aircraft autonomously via data link .The algorithm generating the trajectories must take into account the performance characteristics of the aircraft, the route structure of the airway system, and be capable of resolving all types of conflicts for properly equipped aircraft without requiring supervision and approval by a controller. Furthermore, the resolution trajectories should be compatible with the clearances, vectors and flight plan amendments that controllers customarily issue to pilots in resolving conflicts. The algorithm described herein, although formulated specifically to meet the needs of the AAC, provides a generic engine for resolving conflicts. Thus, it can be incorporated into any operational concept that requires a method for automated resolution, including concepts for autonomous air to air resolution.

  4. Automation in Clinical Microbiology

    PubMed Central

    Ledeboer, Nathan A.

    2013-01-01

    Historically, the trend toward automation in clinical pathology laboratories has largely bypassed the clinical microbiology laboratory. In this article, we review the historical impediments to automation in the microbiology laboratory and offer insight into the reasons why we believe that we are on the cusp of a dramatic change that will sweep a wave of automation into clinical microbiology laboratories. We review the currently available specimen-processing instruments as well as the total laboratory automation solutions. Lastly, we outline the types of studies that will need to be performed to fully assess the benefits of automation in microbiology laboratories. PMID:23515547

  5. Environmental and faunal change in the Jurassic Sundance Seaway, western United States: a stratigraphic palaeobiological approach

    NASA Astrophysics Data System (ADS)

    Danise, Silvia; Holland, Steven

    2017-04-01

    Understanding how regional ecosystems respond to sea level and environmental perturbations is a main challenge in palaeoecology. Here we use quantitative abundance estimates, integrated within a sequence stratigraphic and environmental framework, to reconstruct benthic community changes through the 13 myr history of the Jurassic Sundance Seaway in the western United States. Faunal censuses of macroinvertebrates were obtained from marine rocks of the Gypsum Spring, Sundance and Twin Creek formations at 44 localities in Wyoming, Montana and South Dakota. Fossils were identified to species wherever possible. Ordination of samples shows a main turnover event at the Middle-Upper Jurassic transition, which coincided with the shift from carbonate to siliciclastic depositional systems in the Seaway. This shift was probably initiated by the northward migration of the North American Plate, which moved the study area from subtropical latitudes, fostering an arid climate, into progressively more humid conditions, and possibly also by global cooling at this time. Turnover was not uniform across the onshore-offshore gradient, but was higher in offshore environments, in both carbonate and siliciclastic settings. Both the Jaccard and the Bray-Curtis similarity measures indicate that taxonomic similarity decreases from onshore to offshore in successive third-order depositional sequences, although similarity values are low for both onshore and offshore environments The higher resilience of onshore communities to third-order sea-level fluctuations and to the change from a carbonate to a siliciclastic system was driven by a few abundant eurytopic species that persisted from the opening to the closing of the Seaway and that were not restricted to single depositional environments or sequences. Lower stability in offshore facies was instead controlled by the presence of more volatile stenotopic species. Such increased onshore stability in community composition contrasts with the well

  6. Automated Analysis of Stateflow Models

    NASA Technical Reports Server (NTRS)

    Bourbouh, Hamza; Garoche, Pierre-Loic; Garion, Christophe; Gurfinkel, Arie; Kahsaia, Temesghen; Thirioux, Xavier

    2017-01-01

    Stateflow is a widely used modeling framework for embedded and cyber physical systems where control software interacts with physical processes. In this work, we present a framework a fully automated safety verification technique for Stateflow models. Our approach is two-folded: (i) we faithfully compile Stateflow models into hierarchical state machines, and (ii) we use automated logic-based verification engine to decide the validity of safety properties. The starting point of our approach is a denotational semantics of State flow. We propose a compilation process using continuation-passing style (CPS) denotational semantics. Our compilation technique preserves the structural and modal behavior of the system. The overall approach is implemented as an open source toolbox that can be integrated into the existing Mathworks Simulink Stateflow modeling framework. We present preliminary experimental evaluations that illustrate the effectiveness of our approach in code generation and safety verification of industrial scale Stateflow models.

  7. Virtual automation.

    PubMed

    Casis, E; Garrido, A; Uranga, B; Vives, A; Zufiaurre, C

    2001-01-01

    Total laboratory automation (TLA) can be substituted in mid-size laboratories by a computer sample workflow control (virtual automation). Such a solution has been implemented in our laboratory using PSM, software developed in cooperation with Roche Diagnostics (Barcelona, Spain), to this purpose. This software is connected to the online analyzers and to the laboratory information system and is able to control and direct the samples working as an intermediate station. The only difference with TLA is the replacement of transport belts by personnel of the laboratory. The implementation of this virtual automation system has allowed us the achievement of the main advantages of TLA: workload increase (64%) with reduction in the cost per test (43%), significant reduction in the number of biochemistry primary tubes (from 8 to 2), less aliquoting (from 600 to 100 samples/day), automation of functional testing, drastic reduction of preanalytical errors (from 11.7 to 0.4% of the tubes) and better total response time for both inpatients (from up to 48 hours to up to 4 hours) and outpatients (from up to 10 days to up to 48 hours). As an additional advantage, virtual automation could be implemented without hardware investment and significant headcount reduction (15% in our lab).

  8. Laboratory automation: total and subtotal.

    PubMed

    Hawker, Charles D

    2007-12-01

    Worldwide, perhaps 2000 or more clinical laboratories have implemented some form of laboratory automation, either a modular automation system, such as for front-end processing, or a total laboratory automation system. This article provides descriptions and examples of these various types of automation. It also presents an outline of how a clinical laboratory that is contemplating automation should approach its decision and the steps it should follow to ensure a successful implementation. Finally, the role of standards in automation is reviewed.

  9. Stratigraphic architecture and depositional history of lower Miocene, Planulina Zone, Southern Louisiana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gates, B.C.; Galloway, W.E.

    1988-01-01

    The Planulina zone is a wedge of clastic sediment positioned between the Anahuac shale below and the Oakville sandstone interval above. Planulna sediments were deposited on an erosional surface, during a general rise in the sea level, and formed a retrogradational wedge. Within the study area, the Planulina zone consists of two large depositional complexes: the Mud Lake complex in west Cameron Parish, Louisiana, and the East Cameron complex in east Cameron Parish. The lowermost depositional sequence in the East Cameron complex is preserved in a network of submarine canyons that were eroded into the upper slope. Framework sands weremore » deposited in channel systems confined to the axis of the canyons, and the sands are encased in marine shale containing benthonic foraminifera indicative of an upper to middle slope paleoenvironment. Two younger depositional sequences overlie the submarine canyon facies and were deposited by deltaic systems that prograded basinward. A zone of expansion extends east to west through the Planulina interval and is named the ''Planulina flexure.'' The flexure is a large fault located at the relict shelf edge and soles out downdip inn the Anahuac shale. Several thousand feet of sediment downthrown on the flexure is equivalent to several hundred feet upthrown, and the flexure represented the boundary dividing updip deltaic processes from downdip slope processes during the beginning of Planulina deposition. The Planulina depositional history and stratigraphic architecture are directly related to the displacement along the flexure and the structural deformation of the underlying Anahuac shale.« less

  10. MyDTW - Dynamic Time Warping program for stratigraphical time series

    NASA Astrophysics Data System (ADS)

    Kotov, Sergey; Paelike, Heiko

    2017-04-01

    One of the general tasks in many geological disciplines is matching of one time or space signal to another. It can be classical correlation between two cores or cross-sections in sedimentology or marine geology. For example, tuning a paleoclimatic signal to a target curve, driven by variations in the astronomical parameters, is a powerful technique to construct accurate time scales. However, these methods can be rather time-consuming and can take ours of routine work even with the help of special semi-automatic software. Therefore, different approaches to automate the processes have been developed during last decades. Some of them are based on classical statistical cross-correlations such as the 'Correlator' after Olea [1]. Another ones use modern ideas of dynamic programming. A good example is as an algorithm developed by Lisiecki and Lisiecki [2] or dynamic time warping based algorithm after Pälike [3]. We introduce here an algorithm and computer program, which are also stemmed from the Dynamic Time Warping algorithm class. Unlike the algorithm of Lisiecki and Lisiecki, MyDTW does not lean on a set of penalties to follow geological logics, but on a special internal structure and specific constrains. It differs also from [3] in basic ideas of implementation and constrains design. The algorithm is implemented as a computer program with a graphical user interface using Free Pascal and Lazarus IDE and available for Windows, Mac OS, and Linux. Examples with synthetic and real data are demonstrated. Program is available for free download at http://www.marum.de/Sergey_Kotov.html . References: 1. Olea, R.A. Expert systems for automated correlation and interpretation of wireline logs // Math Geol (1994) 26: 879. doi:10.1007/BF02083420 2. Lisiecki L. and Lisiecki P. Application of dynamic programming to the correlation of paleoclimate records // Paleoceanography (2002), Volume 17, Issue 4, pp. 1-1, CiteID 1049, doi: 10.1029/2001PA000733 3. Pälike, H. Extending the

  11. Affective processes in human-automation interactions.

    PubMed

    Merritt, Stephanie M

    2011-08-01

    This study contributes to the literature on automation reliance by illuminating the influences of user moods and emotions on reliance on automated systems. Past work has focused predominantly on cognitive and attitudinal variables, such as perceived machine reliability and trust. However, recent work on human decision making suggests that affective variables (i.e., moods and emotions) are also important. Drawing from the affect infusion model, significant effects of affect are hypothesized. Furthermore, a new affectively laden attitude termed liking is introduced. Participants watched video clips selected to induce positive or negative moods, then interacted with a fictitious automated system on an X-ray screening task At five time points, important variables were assessed including trust, liking, perceived machine accuracy, user self-perceived accuracy, and reliance.These variables, along with propensity to trust machines and state affect, were integrated in a structural equation model. Happiness significantly increased trust and liking for the system throughout the task. Liking was the only variable that significantly predicted reliance early in the task. Trust predicted reliance later in the task, whereas perceived machine accuracy and user self-perceived accuracy had no significant direct effects on reliance at any time. Affective influences on automation reliance are demonstrated, suggesting that this decision-making process may be less rational and more emotional than previously acknowledged. Liking for a new system may be key to appropriate reliance, particularly early in the task. Positive affect can be easily induced and may be a lever for increasing liking.

  12. The CADSS design automation system. [computerized design language for small digital systems

    NASA Technical Reports Server (NTRS)

    Franke, E. A.

    1973-01-01

    This research was designed to implement and extend a previously defined design automation system for the design of small digital structures. A description is included of the higher level language developed to describe systems as a sequence of register transfer operations. The system simulator which is used to determine if the original description is correct is also discussed. The design automation system produces tables describing the state transistions of the system and the operation of all registers. In addition all Boolean equations specifying system operation are minimized and converted to NAND gate structures. Suggestions for further extensions to the system are also given.

  13. AIDA: ab initio domain assembly for automated multi-domain protein structure prediction and domain–domain interaction prediction

    PubMed Central

    Xu, Dong; Jaroszewski, Lukasz; Li, Zhanwen; Godzik, Adam

    2015-01-01

    Motivation: Most proteins consist of multiple domains, independent structural and evolutionary units that are often reshuffled in genomic rearrangements to form new protein architectures. Template-based modeling methods can often detect homologous templates for individual domains, but templates that could be used to model the entire query protein are often not available. Results: We have developed a fast docking algorithm ab initio domain assembly (AIDA) for assembling multi-domain protein structures, guided by the ab initio folding potential. This approach can be extended to discontinuous domains (i.e. domains with ‘inserted’ domains). When tested on experimentally solved structures of multi-domain proteins, the relative domain positions were accurately found among top 5000 models in 86% of cases. AIDA server can use domain assignments provided by the user or predict them from the provided sequence. The latter approach is particularly useful for automated protein structure prediction servers. The blind test consisting of 95 CASP10 targets shows that domain boundaries could be successfully determined for 97% of targets. Availability and implementation: The AIDA package as well as the benchmark sets used here are available for download at http://ffas.burnham.org/AIDA/. Contact: adam@sanfordburnham.org Supplementary information: Supplementary data are available at Bioinformatics online. PMID:25701568

  14. Functional MRI Preprocessing in Lesioned Brains: Manual Versus Automated Region of Interest Analysis

    PubMed Central

    Garrison, Kathleen A.; Rogalsky, Corianne; Sheng, Tong; Liu, Brent; Damasio, Hanna; Winstein, Carolee J.; Aziz-Zadeh, Lisa S.

    2015-01-01

    Functional magnetic resonance imaging (fMRI) has significant potential in the study and treatment of neurological disorders and stroke. Region of interest (ROI) analysis in such studies allows for testing of strong a priori clinical hypotheses with improved statistical power. A commonly used automated approach to ROI analysis is to spatially normalize each participant’s structural brain image to a template brain image and define ROIs using an atlas. However, in studies of individuals with structural brain lesions, such as stroke, the gold standard approach may be to manually hand-draw ROIs on each participant’s non-normalized structural brain image. Automated approaches to ROI analysis are faster and more standardized, yet are susceptible to preprocessing error (e.g., normalization error) that can be greater in lesioned brains. The manual approach to ROI analysis has high demand for time and expertise, but may provide a more accurate estimate of brain response. In this study, commonly used automated and manual approaches to ROI analysis were directly compared by reanalyzing data from a previously published hypothesis-driven cognitive fMRI study, involving individuals with stroke. The ROI evaluated is the pars opercularis of the inferior frontal gyrus. Significant differences were identified in task-related effect size and percent-activated voxels in this ROI between the automated and manual approaches to ROI analysis. Task interactions, however, were consistent across ROI analysis approaches. These findings support the use of automated approaches to ROI analysis in studies of lesioned brains, provided they employ a task interaction design. PMID:26441816

  15. Trust in automation: integrating empirical evidence on factors that influence trust.

    PubMed

    Hoff, Kevin Anthony; Bashir, Masooda

    2015-05-01

    We systematically review recent empirical research on factors that influence trust in automation to present a three-layered trust model that synthesizes existing knowledge. Much of the existing research on factors that guide human-automation interaction is centered around trust, a variable that often determines the willingness of human operators to rely on automation. Studies have utilized a variety of different automated systems in diverse experimental paradigms to identify factors that impact operators' trust. We performed a systematic review of empirical research on trust in automation from January 2002 to June 2013. Papers were deemed eligible only if they reported the results of a human-subjects experiment in which humans interacted with an automated system in order to achieve a goal. Additionally, a relationship between trust (or a trust-related behavior) and another variable had to be measured. All together, 101 total papers, containing 127 eligible studies, were included in the review. Our analysis revealed three layers of variability in human-automation trust (dispositional trust, situational trust, and learned trust), which we organize into a model. We propose design recommendations for creating trustworthy automation and identify environmental conditions that can affect the strength of the relationship between trust and reliance. Future research directions are also discussed for each layer of trust. Our three-layered trust model provides a new lens for conceptualizing the variability of trust in automation. Its structure can be applied to help guide future research and develop training interventions and design procedures that encourage appropriate trust. © 2014, Human Factors and Ergonomics Society.

  16. CORE-BASED INTEGRATED SEDIMENTOLOGIC, STRATIGRAPHIC, AND GEOCHEMICAL ANALYSIS OF THE OIL SHALE BEARING GREEN RIVER FORMATION, UINTA BASIN, UTAH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lauren P. Birgenheier; Michael D. Vanden Berg,

    An integrated detailed sedimentologic, stratigraphic, and geochemical study of Utah's Green River Formation has found that Lake Uinta evolved in three phases (1) a freshwater rising lake phase below the Mahogany zone, (2) an anoxic deep lake phase above the base of the Mahogany zone and (3) a hypersaline lake phase within the middle and upper R-8. This long term lake evolution was driven by tectonic basin development and the balance of sediment and water fill with the neighboring basins, as postulated by models developed from the Greater Green River Basin by Carroll and Bohacs (1999). Early Eocene abrupt global-warmingmore » events may have had significant control on deposition through the amount of sediment production and deposition rates, such that lean zones below the Mahogany zone record hyperthermal events and rich zones record periods between hyperthermals. This type of climatic control on short-term and long-term lake evolution and deposition has been previously overlooked. This geologic history contains key points relevant to oil shale development and engineering design including: (1) Stratigraphic changes in oil shale quality and composition are systematic and can be related to spatial and temporal changes in the depositional environment and basin dynamics. (2) The inorganic mineral matrix of oil shale units changes significantly from clay mineral/dolomite dominated to calcite above the base of the Mahogany zone. This variation may result in significant differences in pyrolysis products and geomechanical properties relevant to development and should be incorporated into engineering experiments. (3) This study includes a region in the Uinta Basin that would be highly prospective for application of in-situ production techniques. Stratigraphic targets for in-situ recovery techniques should extend above and below the Mahogany zone and include the upper R-6 and lower R-8.« less

  17. The characteristics of gas hydrates recovered from the Mount Elbert Gas Hydrate Stratigraphic Test Well, Alaska North Slope

    USGS Publications Warehouse

    Lu, H.; Lorenson, T.D.; Moudrakovski, I.L.; Ripmeester, J.A.; Collett, T.S.; Hunter, R.B.; Ratcliffe, C.I.

    2011-01-01

    Systematic analyses have been carried out on two gas hydrate-bearing sediment core samples, HYPV4, which was preserved by CH4 gas pressurization, and HYLN7, which was preserved in liquid-nitrogen, recovered from the BPXA-DOE-USGS Mount Elbert Stratigraphic Test Well. Gas hydrate in the studied core samples was found by observation to have developed in sediment pores, and the distribution of hydrate saturation in the cores imply that gas hydrate had experienced stepwise dissociation before it was stabilized by either liquid nitrogen or pressurizing gas. The gas hydrates were determined to be structure Type I hydrate with hydration numbers of approximately 6.1 by instrumentation methods such as powder X-ray diffraction, Raman spectroscopy and solid state 13C NMR. The hydrate gas composition was predominantly methane, and isotopic analysis showed that the methane was of thermogenic origin (mean ??13C=-48.6??? and ??D=-248??? for sample HYLN7). Isotopic analysis of methane from sample HYPV4 revealed secondary hydrate formation from the pressurizing methane gas during storage. ?? 2010 Elsevier Ltd.

  18. Automation and Optimization of Multipulse Laser Zona Drilling of Mouse Embryos During Embryo Biopsy.

    PubMed

    Wong, Christopher Yee; Mills, James K

    2017-03-01

    Laser zona drilling (LZD) is a required step in many embryonic surgical procedures, for example, assisted hatching and preimplantation genetic diagnosis. LZD involves the ablation of the zona pellucida (ZP) using a laser while minimizing potentially harmful thermal effects on critical internal cell structures. Develop a method for the automation and optimization of multipulse LZD, applied to cleavage-stage embryos. A two-stage optimization is used. The first stage uses computer vision algorithms to identify embryonic structures and determines the optimal ablation zone farthest away from critical structures such as blastomeres. The second stage combines a genetic algorithm with a previously reported thermal analysis of LZD to optimize the combination of laser pulse locations and pulse durations. The goal is to minimize the peak temperature experienced by the blastomeres while creating the desired opening in the ZP. A proof of concept of the proposed LZD automation and optimization method is demonstrated through experiments on mouse embryos with positive results, as adequately sized openings are created. Automation of LZD is feasible and is a viable step toward the automation of embryo biopsy procedures. LZD is a common but delicate procedure performed by human operators using subjective methods to gauge proper LZD procedure. Automation of LZD removes human error to increase the success rate of LZD. Although the proposed methods are developed for cleavage-stage embryos, the same methods may be applied to most types LZD procedures, embryos at different developmental stages, or nonembryonic cells.

  19. Automation of Oklahoma School Library Media Centers: Automation at the Local Level.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Education, Oklahoma City. Library and Learning Resources Section.

    This document outlines a workshop for media specialists--"School Library Automation: Solving the Puzzle"--that is designed to reduce automation anxiety and give a broad overview of the concerns confronting school library media centers planning for or involved in automation. Issues are addressed under the following headings: (1) Levels of School…

  20. Exploring relationships of human-automation interaction consequences on pilots: uncovering subsystems.

    PubMed

    Durso, Francis T; Stearman, Eric J; Morrow, Daniel G; Mosier, Kathleen L; Fischer, Ute; Pop, Vlad L; Feigh, Karen M

    2015-05-01

    We attempted to understand the latent structure underlying the systems pilots use to operate in situations involving human-automation interaction (HAI). HAI is an important characteristic of many modern work situations. Of course, the cognitive subsystems are not immediately apparent by observing a functioning system, but correlations between variables may reveal important relations. The current report examined pilot judgments of 11 HAI dimensions (e.g., Workload, Task Management, Stress/Nervousness, Monitoring Automation, and Cross-Checking Automation) across 48 scenarios that required airline pilots to interact with automation on the flight deck. We found three major clusters of the dimensions identifying subsystems on the flight deck: a workload subsystem, a management subsystem, and an awareness subsystem. Relationships characterized by simple correlations cohered in ways that suggested underlying subsystems consistent with those that had previously been theorized. Understanding the relationship among dimensions affecting HAI is an important aspect in determining how a new piece of automation designed to affect one dimension will affect other dimensions as well. © 2014, Human Factors and Ergonomics Society.

  1. Bioprocessing automation in cell therapy manufacturing: Outcomes of special interest group automation workshop.

    PubMed

    Ball, Oliver; Robinson, Sarah; Bure, Kim; Brindley, David A; Mccall, David

    2018-04-01

    Phacilitate held a Special Interest Group workshop event in Edinburgh, UK, in May 2017. The event brought together leading stakeholders in the cell therapy bioprocessing field to identify present and future challenges and propose potential solutions to automation in cell therapy bioprocessing. Here, we review and summarize discussions from the event. Deep biological understanding of a product, its mechanism of action and indication pathogenesis underpin many factors relating to bioprocessing and automation. To fully exploit the opportunities of bioprocess automation, therapeutics developers must closely consider whether an automation strategy is applicable, how to design an 'automatable' bioprocess and how to implement process modifications with minimal disruption. Major decisions around bioprocess automation strategy should involve all relevant stakeholders; communication between technical and business strategy decision-makers is of particular importance. Developers should leverage automation to implement in-process testing, in turn applicable to process optimization, quality assurance (QA)/ quality control (QC), batch failure control, adaptive manufacturing and regulatory demands, but a lack of precedent and technical opportunities can complicate such efforts. Sparse standardization across product characterization, hardware components and software platforms is perceived to complicate efforts to implement automation. The use of advanced algorithmic approaches such as machine learning may have application to bioprocess and supply chain optimization. Automation can substantially de-risk the wider supply chain, including tracking and traceability, cryopreservation and thawing and logistics. The regulatory implications of automation are currently unclear because few hardware options exist and novel solutions require case-by-case validation, but automation can present attractive regulatory incentives. Copyright © 2018 International Society for Cellular Therapy

  2. Developing a Graphical User Interface to Automate the Estimation and Prediction of Risk Values for Flood Protective Structures using Artificial Neural Network

    NASA Astrophysics Data System (ADS)

    Hasan, M.; Helal, A.; Gabr, M.

    2014-12-01

    In this project, we focus on providing a computer-automated platform for a better assessment of the potential failures and retrofit measures of flood-protecting earth structures, e.g., dams and levees. Such structures play an important role during extreme flooding events as well as during normal operating conditions. Furthermore, they are part of other civil infrastructures such as water storage and hydropower generation. Hence, there is a clear need for accurate evaluation of stability and functionality levels during their service lifetime so that the rehabilitation and maintenance costs are effectively guided. Among condition assessment approaches based on the factor of safety, the limit states (LS) approach utilizes numerical modeling to quantify the probability of potential failures. The parameters for LS numerical modeling include i) geometry and side slopes of the embankment, ii) loading conditions in terms of rate of rising and duration of high water levels in the reservoir, and iii) cycles of rising and falling water levels simulating the effect of consecutive storms throughout the service life of the structure. Sample data regarding the correlations of these parameters are available through previous research studies. We have unified these criteria and extended the risk assessment in term of loss of life through the implementation of a graphical user interface to automate input parameters that divides data into training and testing sets, and then feeds them into Artificial Neural Network (ANN) tool through MATLAB programming. The ANN modeling allows us to predict risk values of flood protective structures based on user feedback quickly and easily. In future, we expect to fine-tune the software by adding extensive data on variations of parameters.

  3. The 1997 core drilling through Ordovician and Silurian strata at Röstånga, S. Sweden: preliminary stratigraphic assessment and regional comparison

    USGS Publications Warehouse

    Bergstrom, Stig M.; Huff, W.D.; Koren', T.; Larsson, K.; Ahlberg, P.; Kolata, Dennis R.

    1999-01-01

    A core drilling at Ro??sta??nga, the first such drilling ever undertaken in this classical Lower Paleozoic outcrop area in W-central Scania, penetrated an approximately 96 m thick succession of Lower Silurian-upper Middle Ordovician marine rocks. The drilling was stopped at a depth of 132.59 m in an interval of crushed rocks, probably a prominent fault zone, that proved impossible to drill through. The core contains a stratigraphical sequence from the basal Upper Llandoverian (Telychian Stage) to the upper Middle Ordovician (Harjuan Stage). The following units are recognized in descending stratigraphic order (approximate thickness in parenthesis): Kallholn Formation (35 m), Lindega??rd Mudstone (27 m), Fja??cka Shale (13 m), Mossen Formation (0.75 m), Skagen Formation (2.5 m), and Sularp Shale (19 m+). Except for the Skagen Formation, the drilled sequence consists of shales and mudstones with occasional thin limestone interbeds and is similar to coeval successions elsewhere in Scania. There are 11 K-bentonite beds in the Kallholn Formation, 2(3?) in the Lindega??rd Mudstone, 1 in the Mossen Formation, 7 in the Skagen Formation, and 33 in the Sularp Shale. The core serves as an excellent Lower Silurian-upper Middle Ordovician reference standard not only for the Ro??sta??nga area but also for southernmost Sweden in general because the cored sequence is the stratigraphically most complete one known anywhere in this region.

  4. Automation effects in a multiloop manual control system

    NASA Technical Reports Server (NTRS)

    Hess, R. A.; Mcnally, B. D.

    1986-01-01

    An experimental and analytical study was undertaken to investigate human interaction with a simple multiloop manual control system in which the human's activity was systematically varied by changing the level of automation. The system simulated was the longitudinal dynamics of a hovering helicopter. The automation-systems-stabilized vehicle responses from attitude to velocity to position and also provided for display automation in the form of a flight director. The control-loop structure resulting from the task definition can be considered a simple stereotype of a hierarchical control system. The experimental study was complemented by an analytical modeling effort which utilized simple crossover models of the human operator. It was shown that such models can be extended to the description of multiloop tasks involving preview and precognitive human operator behavior. The existence of time optimal manual control behavior was established for these tasks and the role which internal models may play in establishing human-machine performance was discussed.

  5. Automation: triumph or trap?

    PubMed

    Smythe, M H

    1997-01-01

    Automation, a hot topic in the laboratory world today, can be a very expensive option. Those who are considering implementing automation can save time and money by examining the issues from the standpoint of an industrial/manufacturing engineer. The engineer not only asks what problems will be solved by automation, but what problems will be created. This article discusses questions that must be asked and answered to ensure that automation efforts will yield real and substantial payoffs.

  6. Brookian stratigraphic plays in the National Petroleum Reserve - Alaska (NPRA)

    USGS Publications Warehouse

    Houseknecht, David W.

    2003-01-01

    The Brookian megasequence in the National Petroleum Reserve in Alaska (NPRA) includes bottomset and clinoform seismic facies of the Torok Formation (mostly Albian age) and generally coeval, topset seismic facies of the uppermost Torok Formation and the Nanushuk Group. These strata are part of a composite total petroleum system involving hydrocarbons expelled from three stratigraphic intervals of source rocks, the Lower Cretaceous gamma-ray zone (GRZ), the Lower Jurassic Kingak Shale, and the Triassic Shublik Formation. The potential for undiscovered oil and gas resources in the Brookian megasequence in NPRA was assessed by defining five plays (assessment units), one in the topset seismic facies and four in the bottomset-clinoform seismic facies. The Brookian Topset Play is estimated to contain between 60 (95-percent probability) and 465 (5-percent probability) million barrels of technically recoverable oil, with a mean (expected value) of 239 million barrels. The Brookian Topset Play is estimated to contain between 0 (95-percent probability) and 679 (5-percent probability) billion cubic feet of technically recoverable, nonassociated natural gas, with a mean (expected value) of 192 billion cubic feet. The Brookian Clinoform North Play, which extends across northern NPRA, is estimated to contain between 538 (95-percent probability) and 2,257 (5-percent probability) million barrels of technically recoverable oil, with a mean (expected value) of 1,306 million barrels. The Brookian Clinoform North Play is estimated to contain between 0 (95-percent probability) and 1,969 (5-percent probability) billion cubic feet of technically recoverable, nonassociated natural gas, with a mean (expected value) of 674 billion cubic feet. The Brookian Clinoform Central Play, which extends across central NPRA, is estimated to contain between 299 (95-percent probability) and 1,849 (5-percent probability) million barrels of technically recoverable oil, with a mean (expected value) of 973

  7. Depositional features and stratigraphic sections in granitic plutons: implications for the emplacement and crystallization of granitic magma

    NASA Astrophysics Data System (ADS)

    Wiebe, R. A.; Collins, W. J.

    1998-09-01

    Many granitic plutons contain sheet-like masses of dioritic to gabbroic rocks or swarms of mafic to intermediate enclaves which represent the input of higher temperature, more mafic magma during crystallization of the granitic plutons. Small-scale structures associated with these bodies (e.g. load-cast and compaction features, silicic pipes extending from granitic layers into adjacent gabbroic sheets) indicate that the sheets and enclave swarms were deposited on a floor of the magma chamber (on granitic crystal mush and beneath crystal-poor magma) while the mafic magma was incompletely crystallized. These structures indicate 'way up', typically toward the interior of the intrusions, and appear to indicate that packages of mafic sheets and enclave concentrations in these plutons are a record of sequential deposition. Hence, these plutons preserve a stratigraphic history of events involved in the construction (filling, replenishment) and crystallization of the magma chamber. The distinctive features of these depositional portions of plutons allow them to be distinguished from sheeted intrusions, which usually preserve mutual intrusive contacts and 'dike-sill' relations of different magma types. The considerable thickness of material that can be interpreted as depositional, and the evidence for replenishment, suggest that magma chamber volumes at any one time were probably much less than the final size of the pluton. Thus, magma chambers may be constructed much more slowly than presently envisaged. The present steep attitudes of these structures in many plutons may have developed gradually as the floor of the chamber (along with the underlying solidified granite and country rock) sank during continuing episodes of magma chamber replenishment. These internal magmatic structures support recent suggestions that the room problem for granites could be largely accommodated by downward movement of country rock beneath the magma chamber.

  8. Total synthesis of TMG-chitotriomycin based on an automated electrochemical assembly of a disaccharide building block.

    PubMed

    Isoda, Yuta; Sasaki, Norihiko; Kitamura, Kei; Takahashi, Shuji; Manmode, Sujit; Takeda-Okuda, Naoko; Tamura, Jun-Ichi; Nokami, Toshiki; Itoh, Toshiyuki

    2017-01-01

    The total synthesis of TMG-chitotriomycin using an automated electrochemical synthesizer for the assembly of carbohydrate building blocks is demonstrated. We have successfully prepared a precursor of TMG-chitotriomycin, which is a structurally-pure tetrasaccharide with typical protecting groups, through the methodology of automated electrochemical solution-phase synthesis developed by us. The synthesis of structurally well-defined TMG-chitotriomycin has been accomplished in 10-steps from a disaccharide building block.

  9. Fuzzy Control/Space Station automation

    NASA Technical Reports Server (NTRS)

    Gersh, Mark

    1990-01-01

    Viewgraphs on fuzzy control/space station automation are presented. Topics covered include: Space Station Freedom (SSF); SSF evolution; factors pointing to automation & robotics (A&R); astronaut office inputs concerning A&R; flight system automation and ground operations applications; transition definition program; and advanced automation software tools.

  10. AAC Best Practice Using Automated Language Activity Monitoring.

    ERIC Educational Resources Information Center

    Hill, Katya; Romich, Barry

    This brief paper describes automated language activity monitoring (LAM), an augmentative and alternative communication (AAC) methodology for the collection, editing, and analysis of language data in structured or natural situations with people who have severe communication disorders. The LAM function records each language event (letters, words,…

  11. Automated spectral classification and the GAIA project

    NASA Technical Reports Server (NTRS)

    Lasala, Jerry; Kurtz, Michael J.

    1995-01-01

    Two dimensional spectral types for each of the stars observed in the global astrometric interferometer for astrophysics (GAIA) mission would provide additional information for the galactic structure and stellar evolution studies, as well as helping in the identification of unusual objects and populations. The classification of the large quantity generated spectra requires that automated techniques are implemented. Approaches for the automatic classification are reviewed, and a metric-distance method is discussed. In tests, the metric-distance method produced spectral types with mean errors comparable to those of human classifiers working at similar resolution. Data and equipment requirements for an automated classification survey, are discussed. A program of auxiliary observations is proposed to yield spectral types and radial velocities for the GAIA-observed stars.

  12. Assessing Biological and Stratigraphic Determinants of Fossil Abundance: A Case Example from the Late Quaternary of Po Plain, Italy

    NASA Astrophysics Data System (ADS)

    Kowalewski, Michal; Azzarone, Michele; Kusnerik, Kristopher; Dexter, Troy; Wittmer, Jacalyn; Scarponi, Daniele

    2017-04-01

    Absolute fossil abundance [AFA] can be defined as a relative concentration of identifiable fossils per unit of sediment. AFA, or "sediment shelliness", is controlled by the interplay between the rate of input of skeletal remains (biological productivity), pace of shell destruction (taphonomy), rate of sedimentation, and sediment compaction. Understanding the relative importance of those drivers can augment both stratigraphic and biological interpretations of the fossil record. Using 336 samples from a network of late Quaternary cores drilled in Po Plain (Italy), we examined the importance of those factors in controlling the stratigraphic distribution of fossils. All samples were vertically and volumetrically equivalent, each representing a 10 cm long interval of a core with a diameter of 7 cm ( 0.375 dm3 sediment per sample). Sample-level estimates of AFA (1) varied over 4 orders of magnitudes (from <4 to 44200 specimens per dm3 of sediment); (2) appeared invariant to core depth (rho=-0.04, p=0.72); (3) were statistically indistinguishable (chi-square=1.53, p=0.46) across systems tracts; and (4) did not vary substantially across facies (chi-square=6.04, p=0.20) representing a wide range of depositional and taphonomic settings. These outcomes indicate that compaction (which should increase downcore), sedimentation rates (which vary predictably across systems tracts), and pace of shell destruction (expected to differ across depositional settings) are unlikely to have played important role in controlling fossils density in the sampled cores. In contrast, samples with very high shell density (AFA > 4000 specimens per dm3) were characterized by exceedingly low evenness reflecting dominance by one super-abundant species (Berger-Parker index > 0.8 in all cases). These super-abundant species were limited to small r-selective mollusks capable of an explosive population growth: the marine corbulid bivalve Lentidium mediterraneum and the brackish hyrdobiid gastropod Ecrobia

  13. Finite Element Modeling of Transient Head Field Associated with Partially Penetrating, Slug Tests in a Heterogeneous Aquifer with Low Permeability, Stratigraphic Zones and Faults

    NASA Astrophysics Data System (ADS)

    Cheng, J.; Johnson, B.; Everett, M.

    2003-12-01

    Preliminary field work shows slug interference tests using an array of multilevel active and monitoring wells have potential of permitting enhanced aquifer characterization. Analysis of these test data, however, ultimately will rely on numerical geophysical inverse models. In order to gain insight as well as to provide synthetic data sets, we use a 3-D finite element analysis (code:FEHM-LANL) to explore the effect of idealized, low permeability, stratigraphical and structural (faults) heterogeneities on the transient head field associated with a slug test in a packer-isolated interval of an open borehole. The borehole and packers are modeled explicitly; wellbore storage is selected to match values of field tests. The homogeneous model exhibits excellent agreement with that of the semi-analytical model of Liu and Butler (1995). Models are axisymmetric with a centrally located slugged interval within a homogenous, isotropic, confined aquifer with embedded, horizontal or vertical zones of lower permeability that represent low permeability strata or faults, respectively. Either one or two horizontal layers are located opposite the borehole packers, which is a common situation at the field site; layer thickness (0.15-0.75 m), permeability contrast (up to 4 orders of magnitude contrast) and lateral continuity of layers are varied between models. The effect of a "hole" in a layer also is assessed. Fault models explore effects of thickness (0.05-0.75 m) and permeability contrast as well as additional effects associated with the offset of low permeability strata. Results of models are represented most clearly by contour maps of time of arrival and normalized amplitude of peak head perturbation, but transient head histories at selected locations provide additional insight. Synthesis of the models is on-going but a few points can be made at present. Spatial patterns are distinctive and allow easy discrimination between stratigraphic and structural impedance features. Time

  14. An Automated Method for High-Definition Transcranial Direct Current Stimulation Modeling*

    PubMed Central

    Huang, Yu; Su, Yuzhuo; Rorden, Christopher; Dmochowski, Jacek; Datta, Abhishek; Parra, Lucas C.

    2014-01-01

    Targeted transcranial stimulation with electric currents requires accurate models of the current flow from scalp electrodes to the human brain. Idiosyncratic anatomy of individual brains and heads leads to significant variability in such current flows across subjects, thus, necessitating accurate individualized head models. Here we report on an automated processing chain that computes current distributions in the head starting from a structural magnetic resonance image (MRI). The main purpose of automating this process is to reduce the substantial effort currently required for manual segmentation, electrode placement, and solving of finite element models. In doing so, several weeks of manual labor were reduced to no more than 4 hours of computation time and minimal user interaction, while current-flow results for the automated method deviated by less than 27.9% from the manual method. Key facilitating factors are the addition of three tissue types (skull, scalp and air) to a state-of-the-art automated segmentation process, morphological processing to correct small but important segmentation errors, and automated placement of small electrodes based on easily reproducible standard electrode configurations. We anticipate that such an automated processing will become an indispensable tool to individualize transcranial direct current stimulation (tDCS) therapy. PMID:23367144

  15. FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform

    PubMed Central

    Gouret, Philippe; Vitiello, Vérane; Balandraud, Nathalie; Gilles, André; Pontarotti, Pierre; Danchin, Etienne GJ

    2005-01-01

    Background Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position and structure, and inferring their function (as well as of other features of genomes). Structural and functional annotation both require the complex chaining of numerous different software, algorithms and methods under the supervision of a biologist. The automation of these pipelines is necessary to manage huge amounts of data released by sequencing projects. Several pipelines already automate some of these complex chaining but still necessitate an important contribution of biologists for supervising and controlling the results at various steps. Results Here we propose an innovative automated platform, FIGENIX, which includes an expert system capable to substitute to human expertise at several key steps. FIGENIX currently automates complex pipelines of structural and functional annotation under the supervision of the expert system (which allows for example to make key decisions, check intermediate results or refine the dataset). The quality of the results produced by FIGENIX is comparable to those obtained by expert biologists with a drastic gain in terms of time costs and avoidance of errors due to the human manipulation of data. Conclusion The core engine and expert system of the FIGENIX platform currently handle complex annotation processes of broad interest for the genomic community. They could be easily adapted to new, or more specialized pipelines, such as for example the annotation of miRNAs, the classification of complex multigenic families, annotation of regulatory elements and other genomic features of interest. PMID:16083500

  16. Automation to improve efficiency of field expedient injury prediction screening.

    PubMed

    Teyhen, Deydre S; Shaffer, Scott W; Umlauf, Jon A; Akerman, Raymond J; Canada, John B; Butler, Robert J; Goffar, Stephen L; Walker, Michael J; Kiesel, Kyle B; Plisky, Phillip J

    2012-07-01

    Musculoskeletal injuries are a primary source of disability in the U.S. Military. Physical training and sports-related activities account for up to 90% of all injuries, and 80% of these injuries are considered overuse in nature. As a result, there is a need to develop an evidence-based musculoskeletal screen that can assist with injury prevention. The purpose of this study was to assess the capability of an automated system to improve the efficiency of field expedient tests that may help predict injury risk and provide corrective strategies for deficits identified. The field expedient tests include survey questions and measures of movement quality, balance, trunk stability, power, mobility, and foot structure and mobility. Data entry for these tests was automated using handheld computers, barcode scanning, and netbook computers. An automated algorithm for injury risk stratification and mitigation techniques was run on a server computer. Without automation support, subjects were assessed in 84.5 ± 9.1 minutes per subject compared with 66.8 ± 6.1 minutes per subject with automation and 47.1 ± 5.2 minutes per subject with automation and process improvement measures (p < 0.001). The average time to manually enter the data was 22.2 ± 7.4 minutes per subject. An additional 11.5 ± 2.5 minutes per subject was required to manually assign an intervention strategy. Automation of this injury prevention screening protocol using handheld devices and netbook computers allowed for real-time data entry and enhanced the efficiency of injury screening, risk stratification, and prescription of a risk mitigation strategy.

  17. Automated deconvolution of structured mixtures from heterogeneous tumor genomic data

    PubMed Central

    Roman, Theodore; Xie, Lu

    2017-01-01

    With increasing appreciation for the extent and importance of intratumor heterogeneity, much attention in cancer research has focused on profiling heterogeneity on a single patient level. Although true single-cell genomic technologies are rapidly improving, they remain too noisy and costly at present for population-level studies. Bulk sequencing remains the standard for population-scale tumor genomics, creating a need for computational tools to separate contributions of multiple tumor clones and assorted stromal and infiltrating cell populations to pooled genomic data. All such methods are limited to coarse approximations of only a few cell subpopulations, however. In prior work, we demonstrated the feasibility of improving cell type deconvolution by taking advantage of substructure in genomic mixtures via a strategy called simplicial complex unmixing. We improve on past work by introducing enhancements to automate learning of substructured genomic mixtures, with specific emphasis on genome-wide copy number variation (CNV) data, as well as the ability to process quantitative RNA expression data, and heterogeneous combinations of RNA and CNV data. We introduce methods for dimensionality estimation to better decompose mixture model substructure; fuzzy clustering to better identify substructure in sparse, noisy data; and automated model inference methods for other key model parameters. We further demonstrate their effectiveness in identifying mixture substructure in true breast cancer CNV data from the Cancer Genome Atlas (TCGA). Source code is available at https://github.com/tedroman/WSCUnmix PMID:29059177

  18. [Morphometry of pulmonary tissue: From manual to high throughput automation].

    PubMed

    Sallon, C; Soulet, D; Tremblay, Y

    2017-12-01

    Weibel's research has shown that any alteration of the pulmonary structure has effects on function. This demonstration required a quantitative analysis of lung structures called morphometry. This is possible thanks to stereology, a set of methods based on principles of geometry and statistics. His work has helped to better understand the morphological harmony of the lung, which is essential for its proper functioning. An imbalance leads to pathophysiology such as chronic obstructive pulmonary disease in adults and bronchopulmonary dysplasia in neonates. It is by studying this imbalance that new therapeutic approaches can be developed. These advances are achievable only through morphometric analytical methods, which are increasingly precise and focused, in particular thanks to the high-throughput automation of these methods. This review makes a comparison between an automated method that we developed in the laboratory and semi-manual methods of morphometric analyzes. The automation of morphometric measurements is a fundamental asset in the study of pulmonary pathophysiology because it is an assurance of robustness, reproducibility and speed. This tool will thus contribute significantly to the acceleration of the race for the development of new drugs. Copyright © 2017 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  19. Asleep at the automated wheel-Sleepiness and fatigue during highly automated driving.

    PubMed

    Vogelpohl, Tobias; Kühn, Matthias; Hummel, Thomas; Vollrath, Mark

    2018-03-20

    Due to the lack of active involvement in the driving situation and due to monotonous driving environments drivers with automation may be prone to become fatigued faster than manual drivers (e.g. Schömig et al., 2015). However, little is known about the progression of fatigue during automated driving and its effects on the ability to take back manual control after a take-over request. In this driving simulator study with Nö=ö60 drivers we used a three factorial 2ö×ö2ö×ö12 mixed design to analyze the progression (12ö×ö5ömin; within subjects) of driver fatigue in drivers with automation compared to manual drivers (between subjects). Driver fatigue was induced as either mainly sleep related or mainly task related fatigue (between subjects). Additionally, we investigated the drivers' reactions to a take-over request in a critical driving scenario to gain insights into the ability of fatigued drivers to regain manual control and situation awareness after automated driving. Drivers in the automated driving condition exhibited facial indicators of fatigue after 15 to 35ömin of driving. Manual drivers only showed similar indicators of fatigue if they suffered from a lack of sleep and then only after a longer period of driving (approx. 40ömin). Several drivers in the automated condition closed their eyes for extended periods of time. In the driving with automation condition mean automation deactivation times after a take-over request were slower for a certain percentage (about 30%) of the drivers with a lack of sleep (Mö=ö3.2; SDö=ö2.1ös) compared to the reaction times after a long drive (Mö=ö2.4; SDö=ö0.9ös). Drivers with automation also took longer than manual drivers to first glance at the speed display after a take-over request and were more likely to stay behind a braking lead vehicle instead of overtaking it. Drivers are unable to stay alert during extended periods of automated driving without non-driving related tasks. Fatigued drivers could

  20. Computer Assisted School Automation (CASA) in Japan.

    ERIC Educational Resources Information Center

    Sakamoto, Takashi; Nakanome, Naoaki

    1991-01-01

    This assessment of the status of computer assisted school automation (CASA) in Japan begins by describing the structure of the Japanese educational system and the roles of CASA in that system. Statistics on various aspects of computers in Japanese schools and the findings of several surveys are cited to report on the present state of educational…

  1. Elements of EAF automation processes

    NASA Astrophysics Data System (ADS)

    Ioana, A.; Constantin, N.; Dragna, E. C.

    2017-01-01

    Our article presents elements of Electric Arc Furnace (EAF) automation. So, we present and analyze detailed two automation schemes: the scheme of electrical EAF automation system; the scheme of thermic EAF automation system. The application results of these scheme of automation consists in: the sensitive reduction of specific consummation of electrical energy of Electric Arc Furnace, increasing the productivity of Electric Arc Furnace, increase the quality of the developed steel, increasing the durability of the building elements of Electric Arc Furnace.

  2. Automated clustering of probe molecules from solvent mapping of protein surfaces: new algorithms applied to hot-spot mapping and structure-based drug design

    NASA Astrophysics Data System (ADS)

    Lerner, Michael G.; Meagher, Kristin L.; Carlson, Heather A.

    2008-10-01

    Use of solvent mapping, based on multiple-copy minimization (MCM) techniques, is common in structure-based drug discovery. The minima of small-molecule probes define locations for complementary interactions within a binding pocket. Here, we present improved methods for MCM. In particular, a Jarvis-Patrick (JP) method is outlined for grouping the final locations of minimized probes into physical clusters. This algorithm has been tested through a study of protein-protein interfaces, showing the process to be robust, deterministic, and fast in the mapping of protein "hot spots." Improvements in the initial placement of probe molecules are also described. A final application to HIV-1 protease shows how our automated technique can be used to partition data too complicated to analyze by hand. These new automated methods may be easily and quickly extended to other protein systems, and our clustering methodology may be readily incorporated into other clustering packages.

  3. Sequence stratigraphic interpretation of parts of Anambra Basin, Nigeria using geophysical well logs and biostratigraphic data

    NASA Astrophysics Data System (ADS)

    Anakwuba, E. K.; Ajaegwu, N. E.; Ejeke, C. F.; Onyekwelu, C. U.; Chinwuko, A. I.

    2018-03-01

    The Anambra basin constitutes the southeastern lower portion of the Benue Trough, which is a large structural depression that is divided into lower, middle and upper parts; and is one of the least studied inland sedimentary basins in Nigeria. Sequence stratigraphic interpretation had been carried out in parts of the Anambra Basin using data from three wells (Alo-1 Igbariam-1 and Ajire-1). Geophysical well logs and biostratigraphic data were integrated in order to identify key bounding surfaces, subdivide the sediment packages, correlate sand continuity and interpret the environment of deposition in the fields. Biostratigraphic interpretation, using foraminifera and plankton population and diversity, reveals five maximum flooding surfaces (MFS) in the fields. Five sequence boundaries (SB) were also identified using the well log analysis. Four 3rd order genetic sequences bounded by maximum flooding surfaces (MFS-1 to MFS-6) were identified in the areas; four complete sequences and one incomplete sequence were identified in both Alo-1 and Igbariam-1 wells while Ajire-1 has an no complete sequence. The identified system tracts delineated comprises Lowstand Systems Tracts (progradational to aggradational to retrogradational packages), Transgressive Systems Tracts (retrogradational packages) and Highstand Systems Tracts (aggradational to progradational packages) in each well. The sand continuity across the fields reveal sands S1 to S5 where S1 is present in Ajire-1 well and Igbariam-1 well but not in Alo-1 well. The sands S4 to S5 run across the three fields at different depths. The formations penetrated by the wells starting from the base are; Nkporo Formation (Campanian), Mamu Formation (Late Campanian to Early Maastrichtian), Ajali Sandstone (Maastrichtian), Nsukka Formation (Late Maastrichtian to Early Palaeocene), Imo Formation (Palaeocene) and Nanka Sand (Eocene). The environments of deposition revealed are from coastal to bathyal. The sands of lowstand system

  4. Total synthesis of TMG-chitotriomycin based on an automated electrochemical assembly of a disaccharide building block

    PubMed Central

    Isoda, Yuta; Sasaki, Norihiko; Kitamura, Kei; Takahashi, Shuji; Manmode, Sujit; Takeda-Okuda, Naoko; Tamura, Jun-ichi

    2017-01-01

    The total synthesis of TMG-chitotriomycin using an automated electrochemical synthesizer for the assembly of carbohydrate building blocks is demonstrated. We have successfully prepared a precursor of TMG-chitotriomycin, which is a structurally-pure tetrasaccharide with typical protecting groups, through the methodology of automated electrochemical solution-phase synthesis developed by us. The synthesis of structurally well-defined TMG-chitotriomycin has been accomplished in 10-steps from a disaccharide building block. PMID:28684973

  5. A LabVIEW based template for user created experiment automation.

    PubMed

    Kim, D J; Fisk, Z

    2012-12-01

    We have developed an expandable software template to automate user created experiments. The LabVIEW based template is easily modifiable to add together user created measurements, controls, and data logging with virtually any type of laboratory equipment. We use reentrant sequential selection to implement sequence script making it possible to wrap a long series of the user created experiments and execute them in sequence. Details of software structure and application examples for scanning probe microscope and automated transport experiments using custom built laboratory electronics and a cryostat are described.

  6. Integration Of Digital Methodologies (Field, Processing, and Presentation) In A Combined Sedimentology/Stratigraphy and Structure Course

    NASA Astrophysics Data System (ADS)

    Malinconico, L. L., Jr.; Sunderlin, D.; Liew, C. W.

    2015-12-01

    Over the course of the last three years we have designed, developed and refined two Apps for the iPad. GeoFieldBook and StratLogger allow for the real-time display of spatial (structural) and temporal (stratigraphic) field data as well as very easy in-field navigation. Field techniques and methods for data acquisition and mapping in the field have dramatically advanced and simplified how we collect and analyze data while in the field. The Apps are not geologic mapping programs, but rather a way of bypassing the analog field book step to acquire digital data directly that can then be used in various analysis programs (GIS, Google Earth, Stereonet, spreadsheet and drawing programs). We now complete all of our fieldwork digitally. GeoFieldBook can be used to collect structural and other field observations. Each record includes location/date/time information, orientation measurements, formation names, text observations and photos taken with the tablet camera. Records are customizable, so users can add fields of their own choosing. Data are displayed on an image base in real time with oriented structural symbols. The image base is also used for in-field navigation. In StratLogger, the user records bed thickness, lithofacies, biofacies, and contact data in preset and modifiable fields. Each bed/unit record may also be photographed and geo-referenced. As each record is collected, a column diagram of the stratigraphic sequence is built in real time, complete with lithology color, lithology texture, and fossil symbols. The recorded data from any measured stratigraphic sequence can be exported as both the live-drawn column image and as a .csv formatted file for use in spreadsheet or other applications. Common to both Apps is the ability to export the data (via .csv files), photographs and maps or stratigraphic columns (images). Since the data are digital they are easily imported into various processing programs (for example for stereoplot analysis). Requiring that all maps

  7. Spatio-temporal variation in groundwater head affected by stratigraphic heterogeneity of the alluvial aquifer in Northwest India

    NASA Astrophysics Data System (ADS)

    van Dijk, W. M.; Joshi, S. K.; Densmore, A. L.; Jackson, C. R.; Sutanudjaja, E.; Lafare, A. E. A.; Gupta, S.; Mackay, J. D.; Mason, P. J.; Sinha, R.

    2017-12-01

    Groundwater is a primary source of freshwater in the alluvial aquifer system of northwestern India. Unsustainable exploitation of the groundwater resources has led to a regional hotspot in groundwater depletion. Rapid groundwater-level decline shows spatial variation, as the effects of various stresses, including precipitation, potential evapotranspiration and abstraction, are likely to be influenced by the stratigraphic and geomorphic heterogeneity between sediment fan and interfan areas (see Geomorphological map in Figure A). We used a transfer function-noise (TFN) time series approach to quantify the effect of the various stress components in the period 1974-2010, based on predefined impulse response functions (IRFs) of von Asmuth et al. (2008). The objective of this study was 1) to acquire the impulse response function of various stresses, 2) assess the spatial estimation parameter (the zeroth moment, M0) of the spatial development of the groundwater head and 3) relate the spatial M0 to the observed stratigraphic and geomorphic heterogeneity. We collected information on the groundwater head pre- and post-monsoon, the district-wise monthly precipitation and potential evapotranspiration, and we modeled the monthly abstraction rate using land-use information. The TFN identified the IRF of precipitation as well as abstraction. The IRF, summarized in the parameter M0, identified a hotspot for the abstraction stress (see M0 spatial map for abstraction in Figure B) at the margins of the Sutlej and Yamuna fans. No hotspot is observed for the precipitation stress, but the M0 for precipitation increases with distance from the Himalayan front. At larger distances from the Himalayan front, observed groundwater head rises cannot be explained by the IRFs for the abstraction and precipitation stresses. This is likely because the current TFN models do not account for other stresses, such as recharge by canal leakage, which are locally important. We conclude that the spatial

  8. Stratigraphic distribution, taphonomy and paleoenvironments of Spinicaudata in the Triassic and Jurassic of the Paraná Basin

    NASA Astrophysics Data System (ADS)

    Jenisch, Alan Gregory; Lehn, Ilana; Gallego, Oscar Florencio; Monferran, Mateo Daniel; Horodyski, Rodrigo Scalise; Faccini, Ubiratan Ferrucio

    2017-12-01

    Due to the chitino-phosphatic nature of Spinicaudata conchostracan exoskeletons, their carapaces exhibit a low preservational potential compared to other bivalve groups. However, the recent studies point towards the increased tolerance of the carapace against the physical processes. Due to this peculiar characteristic, conchostracan carapace have been utilized as precise temporal markers in estimating stratigraphic and taphonomic parameters. The same characteristic also makes the spinicaudatans useful in evaluating the depositional processes and environments. The present work aims at providing a paleoenvironmental and stratigraphic analysis of conchostracans (Spinicaudata) from the Triassic-Jurassic of the Paraná Basin (Santa Maria and Caturrita formations) in terms of the sedimentary facies analysis, depositional system characterization, and analysis of the taphonomic signatures of the fossiliferous horizons within these formations. The results from the taphonomic study delineates the presence of 4 distinct fossil assemblages based on the causative mechanism and fundamental characteristics of the fossil concentrations: two taphonomic assemblages in the laminated mudstone beds deposited from the decanting fine-grained sediments in floodplains; the sandstone beds with plane parallel laminations and dune- and ripple-cross-stratifications deposited from the flooding-related overflow in the floodplains; and the association of laminated mudstone and massive sandstone beds deposited as the river mouth bars. The results show that the taphonomic signatures, e.g., closed valves, may indicate the various patterns of autochthony and allochthony. In the fine-grained floodplain assemblages, the high degree of preservation can be attributed to autochthony in the conchostracans, whereas the preservational condition of floodplain sandstone sheet and mouth bar assemblages point toward parautochthony and even allochthony. Therefore, the preservational quality of conchostracan

  9. 77 FR 48527 - National Customs Automation Program (NCAP) Test Concerning Automated Commercial Environment (ACE...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... Program (NCAP) Test Concerning Automated Commercial Environment (ACE) Simplified Entry: Modification of... Automated Commercial Environment (ACE). The test's participant selection criteria are modified to reflect... (NCAP) test concerning Automated Commercial Environment (ACE) Simplified Entry functionality (Simplified...

  10. Stratigraphic controls on fluid and solute fluxes across the sediment-water interface of an estuary

    USGS Publications Warehouse

    Sawyer, Audrey H.; Lazareva, Olesya; Kroeger, Kevin D.; Crespo, Kyle; Chan, Clara S.; Stieglitz, Thomas; Michael, Holly A.

    2014-01-01

    Shallow stratigraphic features, such as infilled paleovalleys, modify fresh groundwater discharge to coastal waters and fluxes of saltwater and nutrients across the sediment–water interface. We quantify the spatial distribution of shallow surface water–groundwater exchange and nitrogen fluxes near a paleovalley in Indian River Bay, Delaware, using a hand resistivity probe, conventional seepage meters, and pore-water samples. In the interfluve (region outside the paleovalley) most nitrate-rich fresh groundwater discharges rapidly near the coast with little mixing of saline pore water, and nitrogen transport is largely conservative. In the peat-filled paleovalley, fresh groundwater discharge is negligible, and saltwater exchange is deep (∼1 m). Long pore-water residence times and abundant sulfate and organic matter promote sulfate reduction and ammonium production in shallow sediment. Reducing, iron-rich fresh groundwater beneath paleovalley peat discharges diffusely around paleovalley margins offshore. In this zone of diffuse fresh groundwater discharge, saltwater exchange and dispersion are enhanced, ammonium is produced in shallow sediments, and fluxes of ammonium to surface water are large. By modifying patterns of groundwater discharge and the nature of saltwater exchange in shallow sediments, paleovalleys and other stratigraphic features influence the geochemistry of discharging groundwater. Redox reactions near the sediment–water interface affect rates and patterns of geochemical fluxes to coastal surface waters. For example, at this site, more than 99% of the groundwater-borne nitrate flux to the Delaware Inland Bays occurs within the interfluve portion of the coastline, and more than 50% of the ammonium flux occurs at the paleovalley margin.

  11. Potential of Laboratory Execution Systems (LESs) to Simplify the Application of Business Process Management Systems (BPMSs) in Laboratory Automation.

    PubMed

    Neubert, Sebastian; Göde, Bernd; Gu, Xiangyu; Stoll, Norbert; Thurow, Kerstin

    2017-04-01

    Modern business process management (BPM) is increasingly interesting for laboratory automation. End-to-end workflow automation and improved top-level systems integration for information technology (IT) and automation systems are especially prominent objectives. With the ISO Standard Business Process Model and Notation (BPMN) 2.X, a system-independent and interdisciplinary accepted graphical process control notation is provided, allowing process analysis, while also being executable. The transfer of BPM solutions to structured laboratory automation places novel demands, for example, concerning the real-time-critical process and systems integration. The article discusses the potential of laboratory execution systems (LESs) for an easier implementation of the business process management system (BPMS) in hierarchical laboratory automation. In particular, complex application scenarios, including long process chains based on, for example, several distributed automation islands and mobile laboratory robots for a material transport, are difficult to handle in BPMSs. The presented approach deals with the displacement of workflow control tasks into life science specialized LESs, the reduction of numerous different interfaces between BPMSs and subsystems, and the simplification of complex process modelings. Thus, the integration effort for complex laboratory workflows can be significantly reduced for strictly structured automation solutions. An example application, consisting of a mixture of manual and automated subprocesses, is demonstrated by the presented BPMS-LES approach.

  12. Facies associations, depositional environments and stratigraphic framework of the Early Miocene-Pleistocene successions of the Mukah-Balingian Area, Sarawak, Malaysia

    NASA Astrophysics Data System (ADS)

    Murtaza, Muhammad; Rahman, Abdul Hadi Abdul; Sum, Chow Weng; Konjing, Zainey

    2018-02-01

    Thirty-five stratigraphic section exposed along the Mukah-Selangau road in the Mukah-Balingian area have been studied. Sedimentological and palynological data have been integrated to gain a better insight into the depositional architecture of the area. Broadly, the Mukah-Balingian area is dominated by fluvial, floodplain and estuarine related coal-bearing deposits. The Balingian, Begrih and Liang formations have been described and interpreted in terms of seven facies association. These are: FA1 - Fluvial-dominated channel facies association; FA2 - Tide-influenced channel facies association; FA3 - Tide-dominated channel facies association; FA4 - Floodplain facies association; FA5 - Estuarine central basin-mud flats facies association; FA6 - Tidal flat facies association and FA7 - Coastal swamps and marshes facies association. The Balingian Formation is characterised by the transgressive phase in the base, followed by a regressive phase in the upper part. On the basis of the occurrence of Florscheutzia trilobata with Florscheutzia levipoli, the Early to Middle Miocene age has been assigned to the Balingian Formation. The distinct facies pattern and foraminifera species found from the samples taken from the Begrih outcrop imply deposition in the intertidal flats having pronounced fluvio-tidal interactions along the paleo-margin. Foraminiferal data combined with the pronounced occurrence of Stenochlaena laurifolia suggest at least the Late Miocene age for the Begrih Formation. The internal stratigraphic architecture of the Liang Formation is a function of a combination of sea level, stable tectonic and autogenic control. Based on stratigraphic position, the Middle Pliocene to Pleistocene age for the Liang Formation is probable. The Balingian, Begrih and Liang formations display deposits of multiple regressive-transgressive cycles while the sediments were derived from the uplifted Penian high and Rajang group.

  13. Using microwave Doppler radar in automated manufacturing applications

    NASA Astrophysics Data System (ADS)

    Smith, Gregory C.

    Since the beginning of the Industrial Revolution, manufacturers worldwide have used automation to improve productivity, gain market share, and meet growing or changing consumer demand for manufactured products. To stimulate further industrial productivity, manufacturers need more advanced automation technologies: "smart" part handling systems, automated assembly machines, CNC machine tools, and industrial robots that use new sensor technologies, advanced control systems, and intelligent decision-making algorithms to "see," "hear," "feel," and "think" at the levels needed to handle complex manufacturing tasks without human intervention. The investigator's dissertation offers three methods that could help make "smart" CNC machine tools and industrial robots possible: (1) A method for detecting acoustic emission using a microwave Doppler radar detector, (2) A method for detecting tool wear on a CNC lathe using a Doppler radar detector, and (3) An online non-contact method for detecting industrial robot position errors using a microwave Doppler radar motion detector. The dissertation studies indicate that microwave Doppler radar could be quite useful in automated manufacturing applications. In particular, the methods developed may help solve two difficult problems that hinder further progress in automating manufacturing processes: (1) Automating metal-cutting operations on CNC machine tools by providing a reliable non-contact method for detecting tool wear, and (2) Fully automating robotic manufacturing tasks by providing a reliable low-cost non-contact method for detecting on-line position errors. In addition, the studies offer a general non-contact method for detecting acoustic emission that may be useful in many other manufacturing and non-manufacturing areas, as well (e.g., monitoring and nondestructively testing structures, materials, manufacturing processes, and devices). By advancing the state of the art in manufacturing automation, the studies may help

  14. The role of social and ecological processes in structuring animal populations: a case study from automated tracking of wild birds

    PubMed Central

    Farine, Damien R.; Firth, Josh A.; Aplin, Lucy M.; Crates, Ross A.; Culina, Antica; Garroway, Colin J.; Hinde, Camilla A.; Kidd, Lindall R.; Milligan, Nicole D.; Psorakis, Ioannis; Radersma, Reinder; Verhelst, Brecht; Voelkl, Bernhard; Sheldon, Ben C.

    2015-01-01

    Both social and ecological factors influence population process and structure, with resultant consequences for phenotypic selection on individuals. Understanding the scale and relative contribution of these two factors is thus a central aim in evolutionary ecology. In this study, we develop a framework using null models to identify the social and spatial patterns that contribute to phenotypic structure in a wild population of songbirds. We used automated technologies to track 1053 individuals that formed 73 737 groups from which we inferred a social network. Our framework identified that both social and spatial drivers contributed to assortment in the network. In particular, groups had a more even sex ratio than expected and exhibited a consistent age structure that suggested local association preferences, such as preferential attachment or avoidance. By contrast, recent immigrants were spatially partitioned from locally born individuals, suggesting differential dispersal strategies by phenotype. Our results highlight how different scales of social decision-making, ranging from post-natal dispersal settlement to fission–fusion dynamics, can interact to drive phenotypic structure in animal populations. PMID:26064644

  15. Automation in College Libraries.

    ERIC Educational Resources Information Center

    Werking, Richard Hume

    1991-01-01

    Reports the results of a survey of the "Bowdoin List" group of liberal arts colleges. The survey obtained information about (1) automation modules in place and when they had been installed; (2) financing of automation and its impacts on the library budgets; and (3) library director's views on library automation and the nature of the…

  16. Automation: Decision Aid or Decision Maker?

    NASA Technical Reports Server (NTRS)

    Skitka, Linda J.

    1998-01-01

    This study clarified that automation bias is something unique to automated decision making contexts, and is not the result of a general tendency toward complacency. By comparing performance on exactly the same events on the same tasks with and without an automated decision aid, we were able to determine that at least the omission error part of automation bias is due to the unique context created by having an automated decision aid, and is not a phenomena that would occur even if people were not in an automated context. However, this study also revealed that having an automated decision aid did lead to modestly improved performance across all non-error events. Participants in the non- automated condition responded with 83.68% accuracy, whereas participants in the automated condition responded with 88.67% accuracy, across all events. Automated decision aids clearly led to better overall performance when they were accurate. People performed almost exactly at the level of reliability as the automation (which across events was 88% reliable). However, also clear, is that the presence of less than 100% accurate automated decision aids creates a context in which new kinds of errors in decision making can occur. Participants in the non-automated condition responded with 97% accuracy on the six "error" events, whereas participants in the automated condition had only a 65% accuracy rate when confronted with those same six events. In short, the presence of an AMA can lead to vigilance decrements that can lead to errors in decision making.

  17. A catalog of automated analysis methods for enterprise models.

    PubMed

    Florez, Hector; Sánchez, Mario; Villalobos, Jorge

    2016-01-01

    Enterprise models are created for documenting and communicating the structure and state of Business and Information Technologies elements of an enterprise. After models are completed, they are mainly used to support analysis. Model analysis is an activity typically based on human skills and due to the size and complexity of the models, this process can be complicated and omissions or miscalculations are very likely. This situation has fostered the research of automated analysis methods, for supporting analysts in enterprise analysis processes. By reviewing the literature, we found several analysis methods; nevertheless, they are based on specific situations and different metamodels; then, some analysis methods might not be applicable to all enterprise models. This paper presents the work of compilation (literature review), classification, structuring, and characterization of automated analysis methods for enterprise models, expressing them in a standardized modeling language. In addition, we have implemented the analysis methods in our modeling tool.

  18. Sequence stratigraphic re-interpretation of [open quotes]stray[close quotes] sandstones in the Cretaceous Mancos Shale, Book Cliffs, Utah: Implications for exploration models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hampson, G.J.; Howell, J.A.; Flint, S.S.

    1996-01-01

    The Mancos Shale, Book Cliffs, eastern Utah, represents the open marine mudstones of the Cretaceous Western Interior Seaway and contains a number of detached sandstone bodies ([open quotes]Mancos B[close quotes]) which are located 30-150 km down depositional dip from contemporaneous highstand shoreline deposits in the Blackhawk Formation. Examination of these [open quotes]stray[close quotes] sandstones reveals that they do not represent deep water deposition, as previously supposed, but instead comprise three shallow marine facies associations; (1) tidally-influenced fluvial channel fills, (2) fluvially-dominated delta front successions and (3) low-energy shorelines. Tidally-influenced fluvial channel fills are commonly stacked into multistorey bodies at discretemore » stratigraphic levels, thereby defining incised valley fill (IVF) networks. Fluvially-dominated deltas are eroded into by, and lie at the down-dip terminations of, IVFs and are therefore interpreted as falling stage and lowstand shorelines. Low-energy shorelines are inferred to lie along strike from these deltas. The above shallow marine deposits have been mapped at five discrete stratigraphic horizons, which can be either traced or projected up-dip to previously-documented IVFs in the Blackhawk Formation. Their paleocurrents imply that falling stage and lowstand shoreline trends were sub-parallel to mapped highstand shorelines, although there is evidence for a perpendicular lowstand shoreline trend in the east of the study area. This facies and sequence stratigraphic re-interpretation enables predictive exploration modelling of subsurface [open quotes]Mancos B[close quotes] gas reservoir sandstones.« less

  19. Sequence stratigraphic re-interpretation of {open_quotes}stray{close_quotes} sandstones in the Cretaceous Mancos Shale, Book Cliffs, Utah: Implications for exploration models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hampson, G.J.; Howell, J.A.; Flint, S.S.

    1996-12-31

    The Mancos Shale, Book Cliffs, eastern Utah, represents the open marine mudstones of the Cretaceous Western Interior Seaway and contains a number of detached sandstone bodies ({open_quotes}Mancos B{close_quotes}) which are located 30-150 km down depositional dip from contemporaneous highstand shoreline deposits in the Blackhawk Formation. Examination of these {open_quotes}stray{close_quotes} sandstones reveals that they do not represent deep water deposition, as previously supposed, but instead comprise three shallow marine facies associations; (1) tidally-influenced fluvial channel fills, (2) fluvially-dominated delta front successions and (3) low-energy shorelines. Tidally-influenced fluvial channel fills are commonly stacked into multistorey bodies at discrete stratigraphic levels, thereby definingmore » incised valley fill (IVF) networks. Fluvially-dominated deltas are eroded into by, and lie at the down-dip terminations of, IVFs and are therefore interpreted as falling stage and lowstand shorelines. Low-energy shorelines are inferred to lie along strike from these deltas. The above shallow marine deposits have been mapped at five discrete stratigraphic horizons, which can be either traced or projected up-dip to previously-documented IVFs in the Blackhawk Formation. Their paleocurrents imply that falling stage and lowstand shoreline trends were sub-parallel to mapped highstand shorelines, although there is evidence for a perpendicular lowstand shoreline trend in the east of the study area. This facies and sequence stratigraphic re-interpretation enables predictive exploration modelling of subsurface {open_quotes}Mancos B{close_quotes} gas reservoir sandstones.« less

  20. Stratigraphic evidence of desertification in the west-central Great Plains within the past 1000 yr

    USGS Publications Warehouse

    Madole, R.F.

    1994-01-01

    Stratigraphic and geomorphic relations, archaeological data, and eight radiocarbon ages at five widely scattered localities in northeastern Colorado indicate that eolian sand was mobilized over broad areas within the past 1000 yr. The mobilization began after 1 ka, was episodic, and ended at some as yet undetermined time prior to the latter part of the 19th century. Given that climate-model simulations suggest only slight variation in average surface temperature and annual precipitation in this region during the past 1000 yr, this part of the Great Plains evidently is near the threshold of widespread eolian sand transport under the present climate. -Author

  1. Numerical analysis of stiffened shells of revolution. Volume 3: Users' manual for STARS-2B, 2V, shell theory automated for rotational structures, 2 (buckling, vibrations), digital computer programs

    NASA Technical Reports Server (NTRS)

    Svalbonas, V.

    1973-01-01

    The User's manual for the shell theory automated for rotational structures (STARS) 2B and 2V (buckling, vibrations) is presented. Several features of the program are: (1) arbitrary branching of the shell meridians, (2) arbitrary boundary conditions, (3) minimum input requirements to describe a complex, practical shell of revolution structure, and (4) accurate analysis capability using a minimum number of degrees of freedom.

  2. Measuring Individual Differences in the Perfect Automation Schema.

    PubMed

    Merritt, Stephanie M; Unnerstall, Jennifer L; Lee, Deborah; Huber, Kelli

    2015-08-01

    A self-report measure of the perfect automation schema (PAS) is developed and tested. Researchers have hypothesized that the extent to which users possess a PAS is associated with greater decreases in trust after users encounter automation errors. However, no measure of the PAS currently exists. We developed a self-report measure assessing two proposed PAS factors: high expectations and all-or-none thinking about automation performance. In two studies, participants responded to our PAS measure, interacted with imperfect automated aids, and reported trust. Each of the two PAS measure factors demonstrated fit to the hypothesized factor structure and convergent and discriminant validity when compared with propensity to trust machines and trust in a specific aid. However, the high expectations and all-or-none thinking scales showed low intercorrelations and differential relationships with outcomes, suggesting that they might best be considered two separate constructs rather than two subfactors of the PAS. All-or-none thinking had significant associations with decreases in trust following aid errors, whereas high expectations did not. Results therefore suggest that the all-or-none thinking scale may best represent the PAS construct. Our PAS measure (specifically, the all-or-none thinking scale) significantly predicted the severe trust decreases thought to be associated with high PAS. Further, it demonstrated acceptable psychometric properties across two samples. This measure may be used in future work to assess levels of PAS in users of automated systems in either research or applied settings. © 2015, Human Factors and Ergonomics Society.

  3. Laboratory Automation and Middleware.

    PubMed

    Riben, Michael

    2015-06-01

    The practice of surgical pathology is under constant pressure to deliver the highest quality of service, reduce errors, increase throughput, and decrease turnaround time while at the same time dealing with an aging workforce, increasing financial constraints, and economic uncertainty. Although not able to implement total laboratory automation, great progress continues to be made in workstation automation in all areas of the pathology laboratory. This report highlights the benefits and challenges of pathology automation, reviews middleware and its use to facilitate automation, and reviews the progress so far in the anatomic pathology laboratory. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Automated search of control points in surface-based morphometry.

    PubMed

    Canna, Antonietta; Russo, Andrea G; Ponticorvo, Sara; Manara, Renzo; Pepino, Alessandro; Sansone, Mario; Di Salle, Francesco; Esposito, Fabrizio

    2018-04-16

    Cortical surface-based morphometry is based on a semi-automated analysis of structural MRI images. In FreeSurfer, a widespread tool for surface-based analyses, a visual check of gray-white matter borders is followed by the manual placement of control points to drive the topological correction (editing) of segmented data. A novel algorithm combining radial sampling and machine learning is presented for the automated control point search (ACPS). Four data sets with 3 T MRI structural images were used for ACPS validation, including raw data acquired twice in 36 healthy subjects and both raw and FreeSurfer preprocessed data of 125 healthy subjects from public databases. The unedited data from a subgroup of subjects were submitted to manual control point search and editing. The ACPS algorithm was trained on manual control points and tested on new (unseen) unedited data. Cortical thickness (CT) and fractal dimensionality (FD) were estimated in three data sets by reconstructing surfaces from both unedited and edited data, and the effects of editing were compared between manual and automated editing and versus no editing. The ACPS-based editing improved the surface reconstructions similarly to manual editing. Compared to no editing, ACPS-based and manual editing significantly reduced CT and FD in consistent regions across different data sets. Despite the extra processing of control point driven reconstructions, CT and FD estimates were highly reproducible in almost all cortical regions, albeit some problematic regions (e.g. entorhinal cortex) may benefit from different editing. The use of control points improves the surface reconstruction and the ACPS algorithm can automate their search reducing the burden of manual editing. Copyright © 2018 Elsevier Inc. All rights reserved.

  5. H++ 3.0: automating pK prediction and the preparation of biomolecular structures for atomistic molecular modeling and simulations.

    PubMed

    Anandakrishnan, Ramu; Aguilar, Boris; Onufriev, Alexey V

    2012-07-01

    The accuracy of atomistic biomolecular modeling and simulation studies depend on the accuracy of the input structures. Preparing these structures for an atomistic modeling task, such as molecular dynamics (MD) simulation, can involve the use of a variety of different tools for: correcting errors, adding missing atoms, filling valences with hydrogens, predicting pK values for titratable amino acids, assigning predefined partial charges and radii to all atoms, and generating force field parameter/topology files for MD. Identifying, installing and effectively using the appropriate tools for each of these tasks can be difficult for novice and time-consuming for experienced users. H++ (http://biophysics.cs.vt.edu/) is a free open-source web server that automates the above key steps in the preparation of biomolecular structures for molecular modeling and simulations. H++ also performs extensive error and consistency checking, providing error/warning messages together with the suggested corrections. In addition to numerous minor improvements, the latest version of H++ includes several new capabilities and options: fix erroneous (flipped) side chain conformations for HIS, GLN and ASN, include a ligand in the input structure, process nucleic acid structures and generate a solvent box with specified number of common ions for explicit solvent MD.

  6. Stratigraphic evolution of the Late Jurassic Hanifa Formation along the Tuwaiq Escarpment, Saudi Arabia: Evidence for a carbonate ramp system

    NASA Astrophysics Data System (ADS)

    Fallatah, Mohammed I.; Kerans, Charles

    2018-01-01

    A sequence stratigraphic framework of the Late Jurassic (Oxfordian) Hanifa Formation at its exposure in Central Arabia is presented for the first time. This study offers the first high-resolution stratigraphic framework of the Hanifa along the Tuwaiq Escarpment by measuring 15 sections ( 770 m total thickness) over an oblique-to-dip distance of 260 km and collecting 295 samples for petrographic analysis. On the basis of these data, the Hanifa Formation can be subdivided into eight facies; 1) tabular cross-bedded quartz-peloidal-skeletal grainstone, 2) cross-bedded skeletal-peloidal grainstone, 3) bioturbated foraminiferal wackestone/mud-dominated packstone, 4) oncolitic rudstone, 5) stromatoporoid-coral biostrome/bioherm, 6) peloidal/composite-grain grain-dominated packstone/grainstone, 7) bioturbated spiculitic wackestone/mud-dominated packstone, and 8) thinly-bedded argillaceous mudstone/wackestone. The vertical and lateral distributions of these facies along the exposure define their sequence setting using the principals of sequence stratigraphy. By recognizing erosional surfaces, facies offset, and changes in facies proportions, five third-order sequences, with an average duration of 1.1 Myr, are interpreted for the Hanifa Formation. The correlation of the sequences across the study area shows that only four sequences are preserved in the north where shallow-water deposits are well-developed. Facies trends within these sequences are further illustrated in depositional models representing the highstand systems tracts (HST) and the transgressive systems tracts (TST) of the Hanifa Formation. These proposed models represent depositional settings of a carbonate ramp with normal open-marine conditions. The HST depositional model is characterized by a high-energy shoreline and depicts the presence of an offshore, structurally controlled skeletal-peloidal shoal body described here for the first time at the Hanifa exposure in the Hozwa area. This work provides a

  7. Managing laboratory automation

    PubMed Central

    Saboe, Thomas J.

    1995-01-01

    This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed. PMID:18925018

  8. Managing laboratory automation.

    PubMed

    Saboe, T J

    1995-01-01

    This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed.

  9. Automating risk analysis of software design models.

    PubMed

    Frydman, Maxime; Ruiz, Guifré; Heymann, Elisa; César, Eduardo; Miller, Barton P

    2014-01-01

    The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development lifecycle. This paper describes an approach to reduce the need for costly human expertise to perform risk analysis in software, which is common in secure development methodologies, by automating threat modeling. Reducing the dependency on security experts aims at reducing the cost of secure development by allowing non-security-aware developers to apply secure development with little to no additional cost, making secure development more accessible. To automate threat modeling two data structures are introduced, identification trees and mitigation trees, to identify threats in software designs and advise mitigation techniques, while taking into account specification requirements and cost concerns. These are the components of our model for automated threat modeling, AutSEC. We validated AutSEC by implementing it in a tool based on data flow diagrams, from the Microsoft security development methodology, and applying it to VOMS, a grid middleware component, to evaluate our model's performance.

  10. Automating Risk Analysis of Software Design Models

    PubMed Central

    Ruiz, Guifré; Heymann, Elisa; César, Eduardo; Miller, Barton P.

    2014-01-01

    The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development lifecycle. This paper describes an approach to reduce the need for costly human expertise to perform risk analysis in software, which is common in secure development methodologies, by automating threat modeling. Reducing the dependency on security experts aims at reducing the cost of secure development by allowing non-security-aware developers to apply secure development with little to no additional cost, making secure development more accessible. To automate threat modeling two data structures are introduced, identification trees and mitigation trees, to identify threats in software designs and advise mitigation techniques, while taking into account specification requirements and cost concerns. These are the components of our model for automated threat modeling, AutSEC. We validated AutSEC by implementing it in a tool based on data flow diagrams, from the Microsoft security development methodology, and applying it to VOMS, a grid middleware component, to evaluate our model's performance. PMID:25136688

  11. Automated Telerobotic Inspection Of Surfaces

    NASA Technical Reports Server (NTRS)

    Balaram, J.; Prasad, K. Venkatesh

    1996-01-01

    Method of automated telerobotic inspection of surfaces undergoing development. Apparatus implementing method includes video camera that scans over surfaces to be inspected, in manner of mine detector. Images of surfaces compared with reference images to detect flaws. Developed for inspecting external structures of Space Station Freedom for damage from micrometeorites and debris from prior artificial satellites. On Earth, applied to inspection for damage, missing parts, contamination, and/or corrosion on interior surfaces of pipes or exterior surfaces of bridges, towers, aircraft, and ships.

  12. Salt tectonics and sequence-stratigraphic history of minibasins near the Sigsbee Escarpment, Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Montoya, Patricia

    The focus of this research is to understand the stratigraphic and structural evolution of lower-slope minibasins in the Gulf of Mexico by examining the influence of salt tectonics on sediment transport systems and deep-water facies architecture. Results showed that gravitational subsidence and shortening can cause variations in the relief of salt massifs on opposing sides of a minibasin. These bathymetric variations, combined with changes in sedimentation rates through time, affected not only the distribution of deep-water facies inside the minibasins, but also influenced the evolution of sediment transport systems between minibasins. In order to understand the evolution of salt massifs, this dissertation presents a new approach to evaluate qualitatively the rate of relative massif uplift based on depoaxis shifts and channel geometries identified in minibasins surrounded by mobile salt. From these results it was established that compression was long-lived, and that extension only dominated during late intervals. Stratigraphic analyses showed that there is a strong cyclicity in deep-water facies stacking patterns within lower-slope minibasins, related primarily to cyclical changes in sedimentation rates. A typical sequence starts with a period of slow sedimentation associated with drape facies above each sequence boundary. Then, towards the middle and final stages of the sequence, sedimentation rates increase and turbidity flows fill the minibasin. Previous studies describe processes of fill-and-spill for two adjacent minibasins in the upper and middle slope. However, these models fail to adequately explain fill-and-spill processes in lower slope minibasins surrounded by mobile salt. In particular, they do not consider the effect of variations in bathymetric relief of the intervening massif, nor do they examine multidirectional connections between proximal and distal minibasins. A new dynamic-salt fill-and-spill model is proposed in this dissertation in order to

  13. Automated design of degenerate codon libraries.

    PubMed

    Mena, Marco A; Daugherty, Patrick S

    2005-12-01

    Degenerate codon libraries are frequently used in protein engineering and evolution studies but are often limited to targeting a small number of positions to adequately limit the search space. To mitigate this, codon degeneracy can be limited using heuristics or previous knowledge of the targeted positions. To automate design of libraries given a set of amino acid sequences, an algorithm (LibDesign) was developed that generates a set of possible degenerate codon libraries, their resulting size, and their score relative to a user-defined scoring function. A gene library of a specified size can then be constructed that is representative of the given amino acid distribution or that includes specific sequences or combinations thereof. LibDesign provides a new tool for automated design of high-quality protein libraries that more effectively harness existing sequence-structure information derived from multiple sequence alignment or computational protein design data.

  14. The Science of Home Automation

    NASA Astrophysics Data System (ADS)

    Thomas, Brian Louis

    Smart home technologies and the concept of home automation have become more popular in recent years. This popularity has been accompanied by social acceptance of passive sensors installed throughout the home. The subsequent increase in smart homes facilitates the creation of home automation strategies. We believe that home automation strategies can be generated intelligently by utilizing smart home sensors and activity learning. In this dissertation, we hypothesize that home automation can benefit from activity awareness. To test this, we develop our activity-aware smart automation system, CARL (CASAS Activity-aware Resource Learning). CARL learns the associations between activities and device usage from historical data and utilizes the activity-aware capabilities to control the devices. To help validate CARL we deploy and test three different versions of the automation system in a real-world smart environment. To provide a foundation of activity learning, we integrate existing activity recognition and activity forecasting into CARL home automation. We also explore two alternatives to using human-labeled data to train the activity learning models. The first unsupervised method is Activity Detection, and the second is a modified DBSCAN algorithm that utilizes Dynamic Time Warping (DTW) as a distance metric. We compare the performance of activity learning with human-defined labels and with automatically-discovered activity categories. To provide evidence in support of our hypothesis, we evaluate CARL automation in a smart home testbed. Our results indicate that home automation can be boosted through activity awareness. We also find that the resulting automation has a high degree of usability and comfort for the smart home resident.

  15. Stratigraphic controls on seawater intrusion and implications for groundwater management, Dominguez Gap area of Los Angeles, California, USA

    USGS Publications Warehouse

    Nishikawa, T.; Siade, A.J.; Reichard, E.G.; Ponti, D.J.; Canales, A.G.; Johnson, T.A.

    2009-01-01

    Groundwater pumping has led to extensive water-level declines and seawater intrusion in coastal Los Angeles, California (USA). A SUTRA-based solute-transport model was developed to test the hydraulic implications of a sequence-stratigraphic model of the Dominguez Gap area and to assess the effects of water-management scenarios. The model is two-dimensional, vertical and follows an approximate flow line extending from the Pacific Ocean through the Dominguez Gap area. Results indicate that a newly identified fault system can provide a pathway for transport of seawater and that a stratigraphic boundary located between the Bent Spring and Upper Wilmington sequences may control the vertical movement of seawater. Three 50-year water-management scenarios were considered: (1) no change in water-management practices; (2) installation of a slurry wall; and (3) raising inland water levels to 7.6 m above sea level. Scenario 3 was the most effective by reversing seawater intrusion. The effects of an instantaneous 1-m sea-level rise were also tested using water-management scenarios 1 and 3. Results from two 100-year simulations indicate that a 1-m sea-level rise may accelerate seawater intrusion for scenario 1; however, scenario 3 remains effective for controlling seawater intrusion. ?? Springer-Verlag 2009.

  16. A unique fossil record from neptunian sills: the world's most extreme example of stratigraphic condensation (Jurassic, western Sicily)

    NASA Astrophysics Data System (ADS)

    Wendt, Jobst

    2017-06-01

    Neptunian sills at Rocca Busambra, a fragment of the Trapanese/Saccense Domain in western Sicily, host the most abundant ammonite and gastropod fauna which has ever been recorded from the Jurassic of the western Tethys. The fauna is dominated by parautochthonous organisms which were swept into the sills by gentle transport. Ammonites are characterized by perfect preservation and small size, a feature which is due to the predominance of microconchs but also of stunting. The most complete sill is 0.7 m thick and could be separated into 17 levels which range in age from the early Toarcian into the late Kimmeridgian, thus representing the most extreme case of palaeontologically and depositionally documented stratigraphic condensation in Earth history. The unique feature of the Rocca Busambra sills is due to the interaction of three processes: extreme stratigraphic condensation on the sea floor, weak tectonic fracturing of the host rock and repeated reopening on top of already existing sills. Contrasting percentages of gastropods in individual levels reflect sea-level oscillations which correspond to long known low- and highstands during the Jurassic of the western Tethys. Comparisons with other ammonite-bearing sill faunas reveal several similarities, but represent only short-timed phases of tectonic pulses and deposition.

  17. Sedimentological and Stratigraphic Associations of Earlandia Foraminifera; in the Early Triassic Succession of Khuff Carbonates; Central Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Adam, Ammar; Kaminski, Michael; Abdullatif, Osman

    2017-04-01

    This work reports the first discovery Earlandia foraminifera in the Triassic succession of the Middle East, within the Upper Khartam Member of the Khuff Formation. The study area is located in central Saudi Arabia where four outcrop localities were logged in detail for sedimentology and micropaleontology. More than 300 samples were collected for detailed sedimentological and micropaleontological analysis. Of these, only six samples recovered fossil Earlandia; these are dominantly observed in the interlaminated quartz-bearing recrystallized limestone lithofacies type. The Earlandia occur in associations with quartz grains, peloids, ooids, ostracods, bivalves, bryozoans, cephalopods, and stromatolites. The defined fossils of Earlandia are restricted to the lower fourth-order sequence of the Upper Khartam member; where non-skeletal grains (mostly oolitic grainstones) prevail. The skeletal grains along with the Earlandia occur as a thin (20 cm) transgressive lag. Furthermore, the regional occurrences of the Earlandia are consistent with the previously established high-frequency sequence stratigraphic scheme, therefore, the Earlandia could be used as a biomarker for regional biostratigraphic correlation and enhance the high-resolution sequence stratigraphic correlations of the Upper Khartam Member. Essentially, the detailed sedimentological and micropaleontological analysis (Earlandia foraminifera) indicates a plate-wide extensive shallow epeiric sea. The latter is gently dipping and sporadically connected to the open marine system.

  18. Automated artery-venous classification of retinal blood vessels based on structural mapping method

    NASA Astrophysics Data System (ADS)

    Joshi, Vinayak S.; Garvin, Mona K.; Reinhardt, Joseph M.; Abramoff, Michael D.

    2012-03-01

    Retinal blood vessels show morphologic modifications in response to various retinopathies. However, the specific responses exhibited by arteries and veins may provide a precise diagnostic information, i.e., a diabetic retinopathy may be detected more accurately with the venous dilatation instead of average vessel dilatation. In order to analyze the vessel type specific morphologic modifications, the classification of a vessel network into arteries and veins is required. We previously described a method for identification and separation of retinal vessel trees; i.e. structural mapping. Therefore, we propose the artery-venous classification based on structural mapping and identification of color properties prominent to the vessel types. The mean and standard deviation of each of green channel intensity and hue channel intensity are analyzed in a region of interest around each centerline pixel of a vessel. Using the vector of color properties extracted from each centerline pixel, it is classified into one of the two clusters (artery and vein), obtained by the fuzzy-C-means clustering. According to the proportion of clustered centerline pixels in a particular vessel, and utilizing the artery-venous crossing property of retinal vessels, each vessel is assigned a label of an artery or a vein. The classification results are compared with the manually annotated ground truth (gold standard). We applied the proposed method to a dataset of 15 retinal color fundus images resulting in an accuracy of 88.28% correctly classified vessel pixels. The automated classification results match well with the gold standard suggesting its potential in artery-venous classification and the respective morphology analysis.

  19. Automated pulmonary lobar ventilation measurements using volume-matched thoracic CT and MRI

    NASA Astrophysics Data System (ADS)

    Guo, F.; Svenningsen, S.; Bluemke, E.; Rajchl, M.; Yuan, J.; Fenster, A.; Parraga, G.

    2015-03-01

    Objectives: To develop and evaluate an automated registration and segmentation pipeline for regional lobar pulmonary structure-function measurements, using volume-matched thoracic CT and MRI in order to guide therapy. Methods: Ten subjects underwent pulmonary function tests and volume-matched 1H and 3He MRI and thoracic CT during a single 2-hr visit. CT was registered to 1H MRI using an affine method that incorporated block-matching and this was followed by a deformable step using free-form deformation. The resultant deformation field was used to deform the associated CT lobe mask that was generated using commercial software. 3He-1H image registration used the same two-step registration method and 3He ventilation was segmented using hierarchical k-means clustering. Whole lung and lobar 3He ventilation and ventilation defect percent (VDP) were generated by mapping ventilation defects to CT-defined whole lung and lobe volumes. Target CT-3He registration accuracy was evaluated using region- , surface distance- and volume-based metrics. Automated whole lung and lobar VDP was compared with semi-automated and manual results using paired t-tests. Results: The proposed pipeline yielded regional spatial agreement of 88.0+/-0.9% and surface distance error of 3.9+/-0.5 mm. Automated and manual whole lung and lobar ventilation and VDP were not significantly different and they were significantly correlated (r = 0.77, p < 0.0001). Conclusion: The proposed automated pipeline can be used to generate regional pulmonary structural-functional maps with high accuracy and robustness, providing an important tool for image-guided pulmonary interventions.

  20. Stratigraphic records of paleogeography and global change from two late Proterozoic basins

    NASA Astrophysics Data System (ADS)

    Swanson-Hysell, Nicholas L.

    As sediments and volcanic deposits accumulate on Earth's surface, they record information about Earth's climate, the motion of continents, and the evolution of the biosphere. Through the study of ancient stratigraphic sequences, we can gain a window into our planet's varied, and sometimes tumultuous, past. In this dissertation, I employ a combination of field observations, magnetic data, and chemostratigraphic data in the Keweenawan Mid-continent Rift of North America and the Amadeus Basin of Central Australia to study the paleogeography and paleoclimate during and after the transition between the Mesoproterozoic (1.7 to 1.0 billion-years ago) and Neoproterozoic Eras (1.0 to 0.54 billion-years ago). The supercontinent Rodinia formed at the boundary between the Eras and broke apart throughout the Neoproterozoic. Basins that developed as Rodinia rifted apart record large changes in the biogeochemical cycling of carbon and sulfur, the waxing and waning of low-latitude ice sheets, and the progressive oxygenation of the atmosphere that facilitated the evolution of animals. I report high-resolution paleomagnetic data in stratigraphic context from Mamainse Point, Ontario---the most complete succession in the 1.1 billion-year-old Mid-continent Rift. The results demonstrate that previous suggestions of large non-dipolar geomagnetic field components at the time stemmed from low temporal resolution across geomagnetic reversals during a period of rapid plate motion. This result strengthens the framework for evaluating records of tectonics and climate across the Mesoproterozoic/Neoproterozoic boundary. Rock magnetic experiments on Mamainse Point lavas, paired with electron microscopy, demonstrate that a component of the magnetization in oxidized flows that is antiparallel to the characteristic remanence is a result of martite self-reversal. This component is the best resolved natural example of the experimentally observed self-reversal that accompanies the maghemite to hematite

  1. Automation in organizations: Eternal conflict

    NASA Technical Reports Server (NTRS)

    Dieterly, D. L.

    1981-01-01

    Some ideas on and insights into the problems associated with automation in organizations are presented with emphasis on the concept of automation, its relationship to the individual, and its impact on system performance. An analogy is drawn, based on an American folk hero, to emphasize the extent of the problems encountered when dealing with automation within an organization. A model is proposed to focus attention on a set of appropriate dimensions. The function allocation process becomes a prominent aspect of the model. The current state of automation research is mentioned in relation to the ideas introduced. Proposed directions for an improved understanding of automation's effect on the individual's efficiency are discussed. The importance of understanding the individual's perception of the system in terms of the degree of automation is highlighted.

  2. A Suggested Automated Branch Program for Foreign Languages.

    ERIC Educational Resources Information Center

    Barrutia, Richard

    1964-01-01

    Completely automated and operated by student feedback, this program teaches and tests foreign language recognition and retention, gives repeated audiolingual practice on model structures, and allows the student to tailor the program to his individual needs. The program is recorded on four tape tracks (track 1 for the most correct answer, etc.).…

  3. Sedimentological and Stratigraphic Controls on Natural Fracture Distribution in Wajid Group, SW Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Benaafi, Mohammed; Hariri, Mustafa; Abdullatif, Osman; Makkawi, Mohammed; Korvin, Gabor

    2016-04-01

    The Cambro-Permian Wajid Group, SW Saudi Arabia, is the main groundwater aquifer in Wadi Al-Dawasir and Najran areas. In addition, it has a reservoir potentiality for oil and natural gas in Rub' Al-Khali Basin. Wajid Group divided into four formations, ascending Dibsiyah, Sanamah, Khussyayan and Juwayl. They are mainly sandstone and exposed in an area extend from Wadi Al-Dawasir southward to Najran city and deposited within fluvial, shallow marine and glacial environments. This study aims to investigate the sedimentological and stratigraphic controls on the distribution of natural fractures within Wajid Group outcrops. A scanline sampling method was used to study the natural fracture network within Wajid Group outcrops, where the natural fractures were measured and characterized in 12 locations. Four regional natural fracture sets were observed with mean strikes of 050o, 075o, 345o, and 320o. Seven lithofacies characterized the Wajid Group at these locations and include fine-grained sandstone, coarse to pebbly sandstone, cross-bedded sandstone, massive sandstone, bioturbated sandstone, conglomerate sandstone, and conglomerate lithofacies. We found that the fine-grained and small scale cross-bedded sandstones lithofacies are characterized by high fracture intensity. In contrast, the coarse-grained sandstone and conglomerate lithofacies have low fracture intensity. Therefore, the relative fracture intensity and spacing of natural fractures within Wajid Group in the subsurface can be predicted by using the lithofacies and their depositional environments. In terms of stratigraphy, we found that the bed thickness and the stratigraphic architecture are the main controls on fractures intensity. The outcomes of this study can help to understand and predict the natural fracture distribution within the subsurface fractured sandstone hosting groundwater and hydrocarbon in Wajid and Rub' Al-Khali Basins. Hence, the finding of this study might help to explore and develop the

  4. Experience of automation failures in training: effects on trust, automation bias, complacency and performance.

    PubMed

    Sauer, Juergen; Chavaillaz, Alain; Wastell, David

    2016-06-01

    This work examined the effects of operators' exposure to various types of automation failures in training. Forty-five participants were trained for 3.5 h on a simulated process control environment. During training, participants either experienced a fully reliable, automatic fault repair facility (i.e. faults detected and correctly diagnosed), a misdiagnosis-prone one (i.e. faults detected but not correctly diagnosed) or a miss-prone one (i.e. faults not detected). One week after training, participants were tested for 3 h, experiencing two types of automation failures (misdiagnosis, miss). The results showed that automation bias was very high when operators trained on miss-prone automation encountered a failure of the diagnostic system. Operator errors resulting from automation bias were much higher when automation misdiagnosed a fault than when it missed one. Differences in trust levels that were instilled by the different training experiences disappeared during the testing session. Practitioner Summary: The experience of automation failures during training has some consequences. A greater potential for operator errors may be expected when an automatic system failed to diagnose a fault than when it failed to detect one.

  5. Advances in in situ inspection of automated fiber placement systems

    NASA Astrophysics Data System (ADS)

    Juarez, Peter D.; Cramer, K. Elliott; Seebo, Jeffrey P.

    2016-05-01

    Automated Fiber Placement (AFP) systems have been developed to help take advantage of the tailorability of composite structures in aerospace applications. AFP systems allow the repeatable placement of uncured, spool fed, preimpregnated carbon fiber tape (tows) onto substrates in desired thicknesses and orientations. This automated process can incur defects, such as overlapping tow lines, which can severely undermine the structural integrity of the part. Current defect detection and abatement methods are very labor intensive, and still mostly rely on human manual inspection. Proposed is a thermographic in situ inspection technique which monitors tow placement with an on board thermal camera using the preheated substrate as a through transmission heat source. An investigation of the concept is conducted, and preliminary laboratory results are presented. Also included will be a brief overview of other emerging technologies that tackle the same issue.

  6. Facies, Stratigraphic and Depositional Model of the Sediments in the Abrolhos Archipelago (Bahia, BRAZIL)

    NASA Astrophysics Data System (ADS)

    Matte, R. R.; Zambonato, E. E.

    2012-04-01

    Located in the Mucuri Basin on the continental shelf of southern Bahia state, northeast Brazil, about 70 km from the city of Caravelas,the Abrolhos archipelago is made up of five islands; Santa Barbara, Redonda, Siriba, Guarita and Sueste. The exhumed sediments in the Abrolhos archipelago are a rare record of the turbidite systems which fill the Brazilian Atlantic Basin, and are probably an unprecedented example of a plataform turbidite system (Dr. Mutti, personal communication). Despite the limited area, the outcrops display a wide facies variation produced by different depositional processes, and also allow for the observation of the layer geometries. Associated with such sedimentary rocks, the Abrolhos Volcanic Complex belongs stratigraphically to the Abrolhos Formation. These igneous rocks were dated by the Ar / Ar method, with ages ranging from 60 to 40 My, placing such Volcanic Complex between the Paleocene and Eocene. The sedimentary section is best exposed in the Santa Barbara and Redonda islands and altogether it is 70 m thick. The measured vertical sections show a good stratigraphic correlation between the rocks of the western portion of the first island and those of Redonda Island. However, there is no correlation between the eastern and western portions of Santa Barbara Island, since they are very likely interrupted by the igneous intrusion and possibly by faulting. The sedimentary stack consists of deposits with alternated regressive and transgressive episodes interpreted as high frequency sequences. The coarse facies, sandstones and conglomerates, with abrupt or erosive bases record regressive phases. On the other hand, finer sandstones and siltstones facies, which are partly bioturbated, correspond to phases of a little sediment supply. In the central and eastern portions of Santa Barbara Island, there is a trend of progradational stacking, while both in the western portion of Santa Barbara and in Redonda islands an agradational trend is observed

  7. Automated Engineering Design (AED); An approach to automated documentation

    NASA Technical Reports Server (NTRS)

    Mcclure, C. W.

    1970-01-01

    The automated engineering design (AED) is reviewed, consisting of a high level systems programming language, a series of modular precoded subroutines, and a set of powerful software machine tools that effectively automate the production and design of new languages. AED is used primarily for development of problem and user-oriented languages. Software production phases are diagramed, and factors which inhibit effective documentation are evaluated.

  8. Site Effects estimation in the Po Plain area (Northern Italy): correlation between passive geophysical surveys and stratigraphic evidence

    NASA Astrophysics Data System (ADS)

    Mascandola, Claudia; Massa, Marco; Barani, Simone; Argnani, Andrea; Poggi, Valerio; Martelli, Luca; Albarello, Dario; Pergalani, Floriana; Compagnoni, Massimo; Lovati, Sara

    2017-04-01

    The recent case of the 2012, Mw 6.1, Emilia seismic sequence (Northern Italy) highlighted the importance of the site effects estimation in the Po Plain, the larger and deeper Italian sedimentary basin. This study, applied on extensive collection of geophysical and geological data in the entire area, allows a macrozonation of the site effects estimation, useful for scientific and applied purpose. In particular, site-response analysis can be performed in defined macrozones, where the geological-geotecnical and geophysical characteristics are homogeneous at macroscale. The collection of the available stratigraphic discontinuities and passive geophysical surveys (single station and array measurements) allowed defining a general macrozonation in terms of amplified frequencies and shear waves velocity (Vs) gradients. The correlation between the obtained geophysical evidence and the known geological information can then be crucial in order to define the most important stratigraphic discontinuities responsible for the local seismic amplification. In particular, ambient vibration data, recorded by all permanent and temporary seismic stations installed in the target region, were collected and then analyzed with the Nakamura technique, to determine the H/V spectral ratio. Moreover, all the available ambient vibration arrays where collected and analyzes to assess the local Vs profile, considering the Rayleigh waves fundamental mode. The Po Plain stratigraphy is defined by regional unconformities (aquifer limits) that have been extensively mapped throughout the basin and by regional geological and structural maps. In general, the H/V results show two ranges of amplified frequencies, both lower than 1 Hz: the former at frequencies lower than about 0.25 Hz and the latter between 0.4 and 1 Hz. The higher frequency range moves from about 0.4 Hz, in the eastern-Adriatic part of the plain, to about 0.8-1.0 Hz in the central and western part. Based on the available seismic array

  9. The 3D Euler solutions using automated Cartesian grid generation

    NASA Technical Reports Server (NTRS)

    Melton, John E.; Enomoto, Francis Y.; Berger, Marsha J.

    1993-01-01

    Viewgraphs on 3-dimensional Euler solutions using automated Cartesian grid generation are presented. Topics covered include: computational fluid dynamics (CFD) and the design cycle; Cartesian grid strategy; structured body fit; grid generation; prolate spheroid; and ONERA M6 wing.

  10. The Automated Office.

    ERIC Educational Resources Information Center

    Naclerio, Nick

    1979-01-01

    Clerical personnel may be able to climb career ladders as a result of office automation and expanded job opportunities in the word processing area. Suggests opportunities in an automated office system and lists books and periodicals on word processing for counselors and teachers. (MF)

  11. KAMO: towards automated data processing for microcrystals.

    PubMed

    Yamashita, Keitaro; Hirata, Kunio; Yamamoto, Masaki

    2018-05-01

    In protein microcrystallography, radiation damage often hampers complete and high-resolution data collection from a single crystal, even under cryogenic conditions. One promising solution is to collect small wedges of data (5-10°) separately from multiple crystals. The data from these crystals can then be merged into a complete reflection-intensity set. However, data processing of multiple small-wedge data sets is challenging. Here, a new open-source data-processing pipeline, KAMO, which utilizes existing programs, including the XDS and CCP4 packages, has been developed to automate whole data-processing tasks in the case of multiple small-wedge data sets. Firstly, KAMO processes individual data sets and collates those indexed with equivalent unit-cell parameters. The space group is then chosen and any indexing ambiguity is resolved. Finally, clustering is performed, followed by merging with outlier rejections, and a report is subsequently created. Using synthetic and several real-world data sets collected from hundreds of crystals, it was demonstrated that merged structure-factor amplitudes can be obtained in a largely automated manner using KAMO, which greatly facilitated the structure analyses of challenging targets that only produced microcrystals. open access.

  12. Systematic review automation technologies

    PubMed Central

    2014-01-01

    Systematic reviews, a cornerstone of evidence-based medicine, are not produced quickly enough to support clinical practice. The cost of production, availability of the requisite expertise and timeliness are often quoted as major contributors for the delay. This detailed survey of the state of the art of information systems designed to support or automate individual tasks in the systematic review, and in particular systematic reviews of randomized controlled clinical trials, reveals trends that see the convergence of several parallel research projects. We surveyed literature describing informatics systems that support or automate the processes of systematic review or each of the tasks of the systematic review. Several projects focus on automating, simplifying and/or streamlining specific tasks of the systematic review. Some tasks are already fully automated while others are still largely manual. In this review, we describe each task and the effect that its automation would have on the entire systematic review process, summarize the existing information system support for each task, and highlight where further research is needed for realizing automation for the task. Integration of the systems that automate systematic review tasks may lead to a revised systematic review workflow. We envisage the optimized workflow will lead to system in which each systematic review is described as a computer program that automatically retrieves relevant trials, appraises them, extracts and synthesizes data, evaluates the risk of bias, performs meta-analysis calculations, and produces a report in real time. PMID:25005128

  13. Stratigraphic cross sections of the Niobrara interval of the Cody Shale and associated rocks in the Wind River Basin, central Wyoming

    USGS Publications Warehouse

    Finn, Thomas M.

    2017-02-07

    The Wind River Basin in Wyoming is one of many structural and sedimentary basins that formed in the Rocky Mountain foreland during the Laramide orogeny. The basin is nearly 200 miles long, 70 miles wide, and encompasses about 7,400 square miles in central Wyoming. The basin is bounded by the Washakie Range, Owl Creek uplift, and southern Bighorn Mountains on the north, the Casper arch on the east, the Granite Mountains on the south, and Wind River Range on the west.Many important conventional oil and gas fields producing from reservoirs ranging in age from Mississippian through Tertiary have been discovered in this basin. In addition, an extensive unconventional overpressured basin-centered gas accumulation has been identified in Cretaceous and Tertiary strata in the deeper parts of the basin. It has long been suggested that various Upper Cretaceous marine shales, including the Cody Shale, are the principal hydrocarbon source rocks for many of these accumulations. With recent advances and success in horizontal drilling and multistage fracture stimulation, there has been an increase in exploration and completion of wells in these marine shales in other Rocky Mountain Laramide basins that were traditionally thought of only as hydrocarbon source rocks.The two stratigraphic cross sections presented in this report were constructed as part of a project carried out by the U.S. Geological Survey to characterize and evaluate the undiscovered continuous (unconventional) oil and gas resources of the Niobrara interval of the Upper Cretaceous Cody Shale in the Wind River Basin in central Wyoming. The primary purpose of the cross sections is to show the stratigraphic relationship of the Niobrara equivalent strata and associated rocks in the lower part of the Cody Shale in the Wind River Basin. These two cross sections were constructed using borehole geophysical logs from 37 wells drilled for oil and gas exploration and production, and one surface section along East Sheep Creek

  14. County-level job automation risk and health: Evidence from the United States.

    PubMed

    Patel, Pankaj C; Devaraj, Srikant; Hicks, Michael J; Wornell, Emily J

    2018-04-01

    Previous studies have observed a positive association between automation risk and employment loss. Based on the job insecurity-health risk hypothesis, greater exposure to automation risk could also be negatively associated with health outcomes. The main objective of this paper is to investigate the county-level association between prevalence of workers in jobs exposed to automation risk and general, physical, and mental health outcomes. As a preliminary assessment of the job insecurity-health risk hypothesis (automation risk → job insecurity → poorer health), a structural equation model was used based on individual-level data in the two cross-sectional waves (2012 and 2014) of General Social Survey (GSS). Next, using county-level data from County Health Rankings 2017, American Community Survey (ACS) 2015, and Statistics of US Businesses 2014, Two Stage Least Squares (2SLS) regression models were fitted to predict county-level health outcomes. Using the 2012 and 2014 waves of the GSS, employees in occupational classes at higher risk of automation reported more job insecurity, that, in turn, was associated with poorer health. The 2SLS estimates show that a 10% increase in automation risk at county-level is associated with 2.38, 0.8, and 0.6 percentage point lower general, physical, and mental health, respectively. Evidence suggests that exposure to automation risk may be negatively associated with health outcomes, plausibly through perceptions of poorer job security. More research is needed on interventions aimed at mitigating negative influence of automation risk on health. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Understanding human management of automation errors.

    PubMed

    McBride, Sara E; Rogers, Wendy A; Fisk, Arthur D

    2014-01-01

    Automation has the potential to aid humans with a diverse set of tasks and support overall system performance. Automated systems are not always reliable, and when automation errs, humans must engage in error management, which is the process of detecting, understanding, and correcting errors. However, this process of error management in the context of human-automation interaction is not well understood. Therefore, we conducted a systematic review of the variables that contribute to error management. We examined relevant research in human-automation interaction and human error to identify critical automation, person, task, and emergent variables. We propose a framework for management of automation errors to incorporate and build upon previous models. Further, our analysis highlights variables that may be addressed through design and training to positively influence error management. Additional efforts to understand the error management process will contribute to automation designed and implemented to support safe and effective system performance.

  16. The Automation-by-Expertise-by-Training Interaction.

    PubMed

    Strauch, Barry

    2017-03-01

    I introduce the automation-by-expertise-by-training interaction in automated systems and discuss its influence on operator performance. Transportation accidents that, across a 30-year interval demonstrated identical automation-related operator errors, suggest a need to reexamine traditional views of automation. I review accident investigation reports, regulator studies, and literature on human computer interaction, expertise, and training and discuss how failing to attend to the interaction of automation, expertise level, and training has enabled operators to commit identical automation-related errors. Automated systems continue to provide capabilities exceeding operators' need for effective system operation and provide interfaces that can hinder, rather than enhance, operator automation-related situation awareness. Because of limitations in time and resources, training programs do not provide operators the expertise needed to effectively operate these automated systems, requiring them to obtain the expertise ad hoc during system operations. As a result, many do not acquire necessary automation-related system expertise. Integrating automation with expected operator expertise levels, and within training programs that provide operators the necessary automation expertise, can reduce opportunities for automation-related operator errors. Research to address the automation-by-expertise-by-training interaction is needed. However, such research must meet challenges inherent to examining realistic sociotechnical system automation features with representative samples of operators, perhaps by using observational and ethnographic research. Research in this domain should improve the integration of design and training and, it is hoped, enhance operator performance.

  17. A Fully Automated High-Throughput Zebrafish Behavioral Ototoxicity Assay.

    PubMed

    Todd, Douglas W; Philip, Rohit C; Niihori, Maki; Ringle, Ryan A; Coyle, Kelsey R; Zehri, Sobia F; Zabala, Leanne; Mudery, Jordan A; Francis, Ross H; Rodriguez, Jeffrey J; Jacob, Abraham

    2017-08-01

    Zebrafish animal models lend themselves to behavioral assays that can facilitate rapid screening of ototoxic, otoprotective, and otoregenerative drugs. Structurally similar to human inner ear hair cells, the mechanosensory hair cells on their lateral line allow the zebrafish to sense water flow and orient head-to-current in a behavior called rheotaxis. This rheotaxis behavior deteriorates in a dose-dependent manner with increased exposure to the ototoxin cisplatin, thereby establishing itself as an excellent biomarker for anatomic damage to lateral line hair cells. Building on work by our group and others, we have built a new, fully automated high-throughput behavioral assay system that uses automated image analysis techniques to quantify rheotaxis behavior. This novel system consists of a custom-designed swimming apparatus and imaging system consisting of network-controlled Raspberry Pi microcomputers capturing infrared video. Automated analysis techniques detect individual zebrafish, compute their orientation, and quantify the rheotaxis behavior of a zebrafish test population, producing a powerful, high-throughput behavioral assay. Using our fully automated biological assay to test a standardized ototoxic dose of cisplatin against varying doses of compounds that protect or regenerate hair cells may facilitate rapid translation of candidate drugs into preclinical mammalian models of hearing loss.

  18. Automated Microwave Dielectric Constant Measurement

    DTIC Science & Technology

    1987-03-01

    IJSWC TR 86-46 AD.-A 184 182 AUTOMATED MICROWAVE DIELECTRIC CONSTANT MEASUREMENT SYTIEM BY B. C. GLANCY A. KRALL PESEARCH AND TECHNOLOGY DEPARTMENT...NO0. NO. ACCESSION NO. Silver Spring, Maryland 20903-500061152N ZROO1 ZRO131 R1AA29 11. TITLE (Include Security Classification) AUTOMATED MICROWAVE ...constants as a funct on of microwave frequency has been simplified using an automated testing apparatus. This automated procedure is based on the use of a

  19. Andean stratigraphic record of the transition from backarc extension to orogenic shortening: A case study from the northern Neuquén Basin, Argentina

    NASA Astrophysics Data System (ADS)

    Horton, Brian K.; Fuentes, Facundo; Boll, Andrés; Starck, Daniel; Ramirez, Sebastian G.; Stockli, Daniel F.

    2016-11-01

    originally derived from basement and magmatic arc sources. The mid-Cenozoic stratigraphic gap signified ∼20 Myr of nondeposition, potentially during passage of a flexural forebulge or during neutral to extensional conditions driven by mechanical decoupling and a possible retreating-slab configuration along the Nazca-South America plate boundary. Neogene eastward propagation of the Malargüe fold-thrust belt involved basement inversion with geometrically and kinematically linked thin-skinned shortening at shallow foreland levels, including late Miocene deposition of accurately dated 10.5-7.5 Ma growth strata and ensuing displacement along the frontal emergent and blind thrust structures. Subsequent partitioning and exhumation of Cenozoic clastic fill of the Malargüe foreland basin has been driven by inboard advance of arc magmatism and Pliocene-Quaternary uplift of the San Rafael basement block farther east.

  20. Understanding human management of automation errors

    PubMed Central

    McBride, Sara E.; Rogers, Wendy A.; Fisk, Arthur D.

    2013-01-01

    Automation has the potential to aid humans with a diverse set of tasks and support overall system performance. Automated systems are not always reliable, and when automation errs, humans must engage in error management, which is the process of detecting, understanding, and correcting errors. However, this process of error management in the context of human-automation interaction is not well understood. Therefore, we conducted a systematic review of the variables that contribute to error management. We examined relevant research in human-automation interaction and human error to identify critical automation, person, task, and emergent variables. We propose a framework for management of automation errors to incorporate and build upon previous models. Further, our analysis highlights variables that may be addressed through design and training to positively influence error management. Additional efforts to understand the error management process will contribute to automation designed and implemented to support safe and effective system performance. PMID:25383042

  1. Automated installation methods for photovoltaic arrays

    NASA Astrophysics Data System (ADS)

    Briggs, R.; Daniels, A.; Greenaway, R.; Oster, J., Jr.; Racki, D.; Stoeltzing, R.

    1982-11-01

    Since installation expenses constitute a substantial portion of the cost of a large photovoltaic power system, methods for reduction of these costs were investigated. The installation of the photovoltaic arrays includes all areas, starting with site preparation (i.e., trenching, wiring, drainage, foundation installation, lightning protection, grounding and installation of the panel) and concluding with the termination of the bus at the power conditioner building. To identify the optimum combination of standard installation procedures and automated/mechanized techniques, the installation process was investigated including the equipment and hardware available, the photovoltaic array structure systems and interfaces, and the array field and site characteristics. Preliminary designs of hardware for both the standard installation method, the automated/mechanized method, and a mix of standard installation procedures and mechanized procedures were identified to determine which process effectively reduced installation costs. In addition, costs associated with each type of installation method and with the design, development and fabrication of new installation hardware were generated.

  2. Means of storage and automated monitoring of versions of text technical documentation

    NASA Astrophysics Data System (ADS)

    Leonovets, S. A.; Shukalov, A. V.; Zharinov, I. O.

    2018-03-01

    The paper presents automation of the process of preparation, storage and monitoring of version control of a text designer, and program documentation by means of the specialized software is considered. Automation of preparation of documentation is based on processing of the engineering data which are contained in the specifications and technical documentation or in the specification. Data handling assumes existence of strictly structured electronic documents prepared in widespread formats according to templates on the basis of industry standards and generation by an automated method of the program or designer text document. Further life cycle of the document and engineering data entering it are controlled. At each stage of life cycle, archive data storage is carried out. Studies of high-speed performance of use of different widespread document formats in case of automated monitoring and storage are given. The new developed software and the work benches available to the developer of the instrumental equipment are described.

  3. Cockpit Adaptive Automation and Pilot Performance

    NASA Technical Reports Server (NTRS)

    Parasuraman, Raja

    2001-01-01

    The introduction of high-level automated systems in the aircraft cockpit has provided several benefits, e.g., new capabilities, enhanced operational efficiency, and reduced crew workload. At the same time, conventional 'static' automation has sometimes degraded human operator monitoring performance, increased workload, and reduced situation awareness. Adaptive automation represents an alternative to static automation. In this approach, task allocation between human operators and computer systems is flexible and context-dependent rather than static. Adaptive automation, or adaptive task allocation, is thought to provide for regulation of operator workload and performance, while preserving the benefits of static automation. In previous research we have reported beneficial effects of adaptive automation on the performance of both pilots and non-pilots of flight-related tasks. For adaptive systems to be viable, however, such benefits need to be examined jointly in the context of a single set of tasks. The studies carried out under this project evaluated a systematic method for combining different forms of adaptive automation. A model for effective combination of different forms of adaptive automation, based on matching adaptation to operator workload was proposed and tested. The model was evaluated in studies using IFR-rated pilots flying a general-aviation simulator. Performance, subjective, and physiological (heart rate variability, eye scan-paths) measures of workload were recorded. The studies compared workload-based adaptation to to non-adaptive control conditions and found evidence for systematic benefits of adaptive automation. The research provides an empirical basis for evaluating the effectiveness of adaptive automation in the cockpit. The results contribute to the development of design principles and guidelines for the implementation of adaptive automation in the cockpit, particularly in general aviation, and in other human-machine systems. Project goals

  4. Automated Bilingual Circulation System Using PC Local Area Networks.

    ERIC Educational Resources Information Center

    Iskanderani, A. I.; Anwar, M. A.

    1992-01-01

    Describes a personal computer and LAN-based automated circulation system capable of handling both Arabic and Latin characters that was developed for use at King Abdullaziz University (Jeddah, Saudi Arabia). Outlines system requirements, system structure, hardware needs, and individual functional modules of the system. Numerous examples and flow…

  5. An automated metrics system to measure and improve the success of laboratory automation implementation.

    PubMed

    Benn, Neil; Turlais, Fabrice; Clark, Victoria; Jones, Mike; Clulow, Stephen

    2007-03-01

    The authors describe a system for collecting usage metrics from widely distributed automation systems. An application that records and stores usage data centrally, calculates run times, and charts the data was developed. Data were collected over 20 months from at least 28 workstations. The application was used to plot bar charts of date versus run time for individual workstations, the automation in a specific laboratory, or automation of a specified type. The authors show that revised user training, redeployment of equipment, and running complimentary processes on one workstation can increase the average number of runs by up to 20-fold and run times by up to 450%. Active monitoring of usage leads to more effective use of automation. Usage data could be used to determine whether purchasing particular automation was a good investment.

  6. Team-Centered Perspective for Adaptive Automation Design

    NASA Technical Reports Server (NTRS)

    Prinzel, Lawrence J., III

    2003-01-01

    Automation represents a very active area of human factors research. The journal, Human Factors, published a special issue on automation in 1985. Since then, hundreds of scientific studies have been published examining the nature of automation and its interaction with human performance. However, despite a dramatic increase in research investigating human factors issues in aviation automation, there remain areas that need further exploration. This NASA Technical Memorandum describes a new area of automation design and research, called adaptive automation. It discusses the concepts and outlines the human factors issues associated with the new method of adaptive function allocation. The primary focus is on human-centered design, and specifically on ensuring that adaptive automation is from a team-centered perspective. The document shows that adaptive automation has many human factors issues common to traditional automation design. Much like the introduction of other new technologies and paradigm shifts, adaptive automation presents an opportunity to remediate current problems but poses new ones for human-automation interaction in aerospace operations. The review here is intended to communicate the philosophical perspective and direction of adaptive automation research conducted under the Aerospace Operations Systems (AOS), Physiological and Psychological Stressors and Factors (PPSF) project.

  7. Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family.

    PubMed Central

    Gocayne, J; Robinson, D A; FitzGerald, M G; Chung, F Z; Kerlavage, A R; Lentes, K U; Lai, J; Wang, C D; Fraser, C M; Venter, J C

    1987-01-01

    Two cDNA clones, lambda RHM-MF and lambda RHB-DAR, encoding the muscarinic cholinergic receptor and the beta-adrenergic receptor, respectively, have been isolated from a rat heart cDNA library. The cDNA clones were characterized by restriction mapping and automated DNA sequence analysis utilizing fluorescent dye primers. The rat heart muscarinic receptor consists of 466 amino acids and has a calculated molecular weight of 51,543. The rat heart beta-adrenergic receptor consists of 418 amino acids and has a calculated molecular weight of 46,890. The two cardiac receptors have substantial amino acid homology (27.2% identity, 50.6% with favored substitutions). The rat cardiac beta receptor has 88.0% homology (92.5% with favored substitutions) with the human brain beta receptor and the rat cardiac muscarinic receptor has 94.6% homology (97.6% with favored substitutions) with the porcine cardiac muscarinic receptor. The muscarinic cholinergic and beta-adrenergic receptors appear to be as conserved as hemoglobin and cytochrome c but less conserved than histones and are clearly members of a multigene family. These data support our hypothesis, based upon biochemical and immunological evidence, that suggests considerable structural homology and evolutionary conservation between adrenergic and muscarinic cholinergic receptors. To our knowledge, this is the first report utilizing automated DNA sequence analysis to determine the structure of a gene. Images PMID:2825184

  8. Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family.

    PubMed

    Gocayne, J; Robinson, D A; FitzGerald, M G; Chung, F Z; Kerlavage, A R; Lentes, K U; Lai, J; Wang, C D; Fraser, C M; Venter, J C

    1987-12-01

    Two cDNA clones, lambda RHM-MF and lambda RHB-DAR, encoding the muscarinic cholinergic receptor and the beta-adrenergic receptor, respectively, have been isolated from a rat heart cDNA library. The cDNA clones were characterized by restriction mapping and automated DNA sequence analysis utilizing fluorescent dye primers. The rat heart muscarinic receptor consists of 466 amino acids and has a calculated molecular weight of 51,543. The rat heart beta-adrenergic receptor consists of 418 amino acids and has a calculated molecular weight of 46,890. The two cardiac receptors have substantial amino acid homology (27.2% identity, 50.6% with favored substitutions). The rat cardiac beta receptor has 88.0% homology (92.5% with favored substitutions) with the human brain beta receptor and the rat cardiac muscarinic receptor has 94.6% homology (97.6% with favored substitutions) with the porcine cardiac muscarinic receptor. The muscarinic cholinergic and beta-adrenergic receptors appear to be as conserved as hemoglobin and cytochrome c but less conserved than histones and are clearly members of a multigene family. These data support our hypothesis, based upon biochemical and immunological evidence, that suggests considerable structural homology and evolutionary conservation between adrenergic and muscarinic cholinergic receptors. To our knowledge, this is the first report utilizing automated DNA sequence analysis to determine the structure of a gene.

  9. Toward designing for trust in database automation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Duez, P. P.; Jamieson, G. A.

    Appropriate reliance on system automation is imperative for safe and productive work, especially in safety-critical systems. It is unsafe to rely on automation beyond its designed use; conversely, it can be both unproductive and unsafe to manually perform tasks that are better relegated to automated tools. Operator trust in automated tools mediates reliance, and trust appears to affect how operators use technology. As automated agents become more complex, the question of trust in automation is increasingly important. In order to achieve proper use of automation, we must engender an appropriate degree of trust that is sensitive to changes in operatingmore » functions and context. In this paper, we present research concerning trust in automation in the domain of automated tools for relational databases. Lee and See have provided models of trust in automation. One model developed by Lee and See identifies three key categories of information about the automation that lie along a continuum of attributional abstraction. Purpose-, process-and performance-related information serve, both individually and through inferences between them, to describe automation in such a way as to engender r properly-calibrated trust. Thus, one can look at information from different levels of attributional abstraction as a general requirements analysis for information key to appropriate trust in automation. The model of information necessary to engender appropriate trust in automation [1] is a general one. Although it describes categories of information, it does not provide insight on how to determine the specific information elements required for a given automated tool. We have applied the Abstraction Hierarchy (AH) to this problem in the domain of relational databases. The AH serves as a formal description of the automation at several levels of abstraction, ranging from a very abstract purpose-oriented description to a more concrete description of the resources involved in the automated

  10. The 'problem' with automation - Inappropriate feedback and interaction, not 'over-automation'

    NASA Technical Reports Server (NTRS)

    Norman, D. A.

    1990-01-01

    Automation in high-risk industry is often blamed for causing harm and increasing the chance of human error when failures occur. It is proposed that the problem is not the presence of automation, but rather its inappropriate design. The problem is that the operations are performed appropriately under normal conditions, but there is inadequate feedback and interaction with the humans who must control the overall conduct of the task. The problem is that the automation is at an intermediate level of intelligence, powerful enough to take over control which used to be done by people, but not powerful enough to handle all abnormalities. Moreover, its level of intelligence is insufficient to provide the continual, appropriate feedback that occurs naturally among human operators. To solve this problem, the automation should either be made less intelligent or more so, but the current level is quite inappropriate. The overall message is that it is possible to reduce error through appropriate design considerations.

  11. The Automation of Reserve Processing.

    ERIC Educational Resources Information Center

    Self, James

    1985-01-01

    Describes an automated reserve processing system developed locally at Clemons Library, University of Virginia. Discussion covers developments in the reserve operation at Clemons Library, automation of the processing and circulation functions of reserve collections, and changes in reserve operation performance and staffing needs due to automation.…

  12. Definition and classification of evaluation units for tertiary structure prediction in CASP12 facilitated through semi-automated metrics.

    PubMed

    Abriata, Luciano A; Kinch, Lisa N; Tamò, Giorgio E; Monastyrskyy, Bohdan; Kryshtafovych, Andriy; Dal Peraro, Matteo

    2018-03-01

    For assessment purposes, CASP targets are split into evaluation units. We herein present the official definition of CASP12 evaluation units (EUs) and their classification into difficulty categories. Each target can be evaluated as one EU (the whole target) or/and several EUs (separate structural domains or groups of structural domains). The specific scenario for a target split is determined by the domain organization of available templates, the difference in server performance on separate domains versus combination of the domains, and visual inspection. In the end, 71 targets were split into 96 EUs. Classification of the EUs into difficulty categories was done semi-automatically with the assistance of metrics provided by the Prediction Center. These metrics account for sequence and structural similarities of the EUs to potential structural templates from the Protein Data Bank, and for the baseline performance of automated server predictions. The metrics readily separate the 96 EUs into 38 EUs that should be straightforward for template-based modeling (TBM) and 39 that are expected to be hard for homology modeling and are thus left for free modeling (FM). The remaining 19 borderline evaluation units were dubbed FM/TBM, and were inspected case by case. The article also overviews structural and evolutionary features of selected targets relevant to our accompanying article presenting the assessment of FM and FM/TBM predictions, and overviews structural features of the hardest evaluation units from the FM category. We finally suggest improvements for the EU definition and classification procedures. © 2017 Wiley Periodicals, Inc.

  13. Modeling Increased Complexity and the Reliance on Automation: FLightdeck Automation Problems (FLAP) Model

    NASA Technical Reports Server (NTRS)

    Ancel, Ersin; Shih, Ann T.

    2014-01-01

    This paper highlights the development of a model that is focused on the safety issue of increasing complexity and reliance on automation systems in transport category aircraft. Recent statistics show an increase in mishaps related to manual handling and automation errors due to pilot complacency and over-reliance on automation, loss of situational awareness, automation system failures and/or pilot deficiencies. Consequently, the aircraft can enter a state outside the flight envelope and/or air traffic safety margins which potentially can lead to loss-of-control (LOC), controlled-flight-into-terrain (CFIT), or runway excursion/confusion accidents, etc. The goal of this modeling effort is to provide NASA's Aviation Safety Program (AvSP) with a platform capable of assessing the impacts of AvSP technologies and products towards reducing the relative risk of automation related accidents and incidents. In order to do so, a generic framework, capable of mapping both latent and active causal factors leading to automation errors, is developed. Next, the framework is converted into a Bayesian Belief Network model and populated with data gathered from Subject Matter Experts (SMEs). With the insertion of technologies and products, the model provides individual and collective risk reduction acquired by technologies and methodologies developed within AvSP.

  14. Automation of the aircraft design process

    NASA Technical Reports Server (NTRS)

    Heldenfels, R. R.

    1974-01-01

    The increasing use of the computer to automate the aerospace product development and engineering process is examined with emphasis on structural analysis and design. Examples of systems of computer programs in aerospace and other industries are reviewed and related to the characteristics of aircraft design in its conceptual, preliminary, and detailed phases. Problems with current procedures are identified, and potential improvements from optimum utilization of integrated disciplinary computer programs by a man/computer team are indicated.

  15. Cloud-Based CT Dose Monitoring using the DICOM-Structured Report: Fully Automated Analysis in Regard to National Diagnostic Reference Levels.

    PubMed

    Boos, J; Meineke, A; Rubbert, C; Heusch, P; Lanzman, R S; Aissa, J; Antoch, G; Kröpil, P

    2016-03-01

    To implement automated CT dose data monitoring using the DICOM-Structured Report (DICOM-SR) in order to monitor dose-related CT data in regard to national diagnostic reference levels (DRLs). We used a novel in-house co-developed software tool based on the DICOM-SR to automatically monitor dose-related data from CT examinations. The DICOM-SR for each CT examination performed between 09/2011 and 03/2015 was automatically anonymized and sent from the CT scanners to a cloud server. Data was automatically analyzed in accordance with body region, patient age and corresponding DRL for volumetric computed tomography dose index (CTDIvol) and dose length product (DLP). Data of 36,523 examinations (131,527 scan series) performed on three different CT scanners and one PET/CT were analyzed. The overall mean CTDIvol and DLP were 51.3% and 52.8% of the national DRLs, respectively. CTDIvol and DLP reached 43.8% and 43.1% for abdominal CT (n=10,590), 66.6% and 69.6% for cranial CT (n=16,098) and 37.8% and 44.0% for chest CT (n=10,387) of the compared national DRLs, respectively. Overall, the CTDIvol exceeded national DRLs in 1.9% of the examinations, while the DLP exceeded national DRLs in 2.9% of the examinations. Between different CT protocols of the same body region, radiation exposure varied up to 50% of the DRLs. The implemented cloud-based CT dose monitoring based on the DICOM-SR enables automated benchmarking in regard to national DRLs. Overall the local dose exposure from CT reached approximately 50% of these DRLs indicating that DRL actualization as well as protocol-specific DRLs are desirable. The cloud-based approach enables multi-center dose monitoring and offers great potential to further optimize radiation exposure in radiological departments. • The newly developed software based on the DICOM-Structured Report enables large-scale cloud-based CT dose monitoring • The implemented software solution enables automated benchmarking in regard to national DRLs • The

  16. Reduced dimensionality (3,2)D NMR experiments and their automated analysis: implications to high-throughput structural studies on proteins.

    PubMed

    Reddy, Jithender G; Kumar, Dinesh; Hosur, Ramakrishna V

    2015-02-01

    Protein NMR spectroscopy has expanded dramatically over the last decade into a powerful tool for the study of their structure, dynamics, and interactions. The primary requirement for all such investigations is sequence-specific resonance assignment. The demand now is to obtain this information as rapidly as possible and in all types of protein systems, stable/unstable, soluble/insoluble, small/big, structured/unstructured, and so on. In this context, we introduce here two reduced dimensionality experiments – (3,2)D-hNCOcanH and (3,2)D-hNcoCAnH – which enhance the previously described 2D NMR-based assignment methods quite significantly. Both the experiments can be recorded in just about 2-3 h each and hence would be of immense value for high-throughput structural proteomics and drug discovery research. The applicability of the method has been demonstrated using alpha-helical bovine apo calbindin-D9k P43M mutant (75 aa) protein. Automated assignment of this data using AUTOBA has been presented, which enhances the utility of these experiments. The backbone resonance assignments so derived are utilized to estimate secondary structures and the backbone fold using Web-based algorithms. Taken together, we believe that the method and the protocol proposed here can be used for routine high-throughput structural studies of proteins. Copyright © 2014 John Wiley & Sons, Ltd.

  17. Trust in automation: designing for appropriate reliance.

    PubMed

    Lee, John D; See, Katrina A

    2004-01-01

    Automation is often problematic because people fail to rely upon it appropriately. Because people respond to technology socially, trust influences reliance on automation. In particular, trust guides reliance when complexity and unanticipated situations make a complete understanding of the automation impractical. This review considers trust from the organizational, sociological, interpersonal, psychological, and neurological perspectives. It considers how the context, automation characteristics, and cognitive processes affect the appropriateness of trust. The context in which the automation is used influences automation performance and provides a goal-oriented perspective to assess automation characteristics along a dimension of attributional abstraction. These characteristics can influence trust through analytic, analogical, and affective processes. The challenges of extrapolating the concept of trust in people to trust in automation are discussed. A conceptual model integrates research regarding trust in automation and describes the dynamics of trust, the role of context, and the influence of display characteristics. Actual or potential applications of this research include improved designs of systems that require people to manage imperfect automation.

  18. Automation and Cataloging.

    ERIC Educational Resources Information Center

    Furuta, Kenneth; And Others

    1990-01-01

    These three articles address issues in library cataloging that are affected by automation: (1) the impact of automation and bibliographic utilities on professional catalogers; (2) the effect of the LASS microcomputer software on the cost of authority work in cataloging at the University of Arizona; and (3) online subject heading and classification…

  19. Issues in advanced automation for manipulator control

    NASA Technical Reports Server (NTRS)

    Bejczy, A. K.

    1976-01-01

    This paper provides a brief description and analysis of the main issues in advanced autonomous control of manipulators as seen from a system point of view. The nature of manipulation is analyzed at some depth. A general multilevel structure is outlined for manipulator control organization which includes the human operator at the top level of the control structure. Different approaches to the development of advanced automation of mechanical arms are summarized. Recent work in the JPL teleoperator project is described, including control system, force/torque sensor, and control software development. Some results from control experiments are summarized.

  20. Geochemistry and stratigraphic correlation of basalt lavas beneath the Idaho Chemical Processing Plant, Idaho National Engineering Laboratory

    USGS Publications Warehouse

    Reed, M.F.; Bartholomay, R.C.; Hughes, S.S.

    1997-01-01

    Thirty-nine samples of basaltic core were collected from wells 121 and 123, located approximately 1.8 km apart north and south of the Idaho Chemical Processing Plant at the Idaho National Engineering Laboratory. Samples were collected from depths ranging from 15 to 221 m below land surface for the purpose of establishing stratigraphic correlations between these two wells. Elemental analyses indicate that the basalts consist of three principal chemical types. Two of these types are each represented by a single basalt flow in each well. The third chemical type is represented by many basalt flows and includes a broad range of chemical compositions that is distinguished from the other two types. Basalt flows within the third type were identified by hierarchical K-cluster analysis of 14 representative elements: Fe, Ca, K, Na, Sc, Co, La, Ce, Sm, Eu, Yb, Hf, Ta, and Th. Cluster analyses indicate correlations of basalt flows between wells 121 and 123 at depths of approximately 38-40 m, 125-128 m, 131-137 m, 149-158 m, and 183-198 m. Probable correlations also are indicated for at least seven other depth intervals. Basalt flows in several depth intervals do not correlate on the basis of chemical compositions, thus reflecting possible flow margins in the sequence between the wells. Multi-element chemical data provide a useful method for determining stratigraphic correlations of basalt in the upper 1-2 km of the eastern Snake River Plain.

  1. Performance Analysis of GAME: A Generic Automated Marking Environment

    ERIC Educational Resources Information Center

    Blumenstein, Michael; Green, Steve; Fogelman, Shoshana; Nguyen, Ann; Muthukkumarasamy, Vallipuram

    2008-01-01

    This paper describes the Generic Automated Marking Environment (GAME) and provides a detailed analysis of its performance in assessing student programming projects and exercises. GAME has been designed to automatically assess programming assignments written in a variety of languages based on the "structure" of the source code and the correctness…

  2. Simplified stratigraphic cross sections of the Eocene Green River Formation in the Piceance Basin, northwestern Colorado

    USGS Publications Warehouse

    Dietrich, John D.; Johnson, Ronald C.

    2013-01-01

    Thirteen stratigraphic cross sections of the Eocene Green River Formation in the Piceance Basin of northwestern Colorado are presented in this report. Originally published in a much larger and more detailed form by Self and others (2010), they are shown here in simplified, page-size versions that are easily accessed and used for presentation purposes. Modifications to the original versions include the elimination of the detailed lithologic columns and oil-yield histograms from Fischer assay data and the addition of ground-surface lines to give the depth of the various oil shale units shown on the cross section.

  3. Human-centered aircraft automation: A concept and guidelines

    NASA Technical Reports Server (NTRS)

    Billings, Charles E.

    1991-01-01

    Aircraft automation is examined and its effects on flight crews. Generic guidelines are proposed for the design and use of automation in transport aircraft, in the hope of stimulating increased and more effective dialogue among designers of automated cockpits, purchasers of automated aircraft, and the pilots who must fly those aircraft in line operations. The goal is to explore the means whereby automation may be a maximally effective tool or resource for pilots without compromising human authority and with an increase in system safety. After definition of the domain of the aircraft pilot and brief discussion of the history of aircraft automation, a concept of human centered automation is presented and discussed. Automated devices are categorized as a control automation, information automation, and management automation. The environment and context of aircraft automation are then considered, followed by thoughts on the likely future of automation of that category.

  4. Algorithms and data structures for automated change detection and classification of sidescan sonar imagery

    NASA Astrophysics Data System (ADS)

    Gendron, Marlin Lee

    During Mine Warfare (MIW) operations, MIW analysts perform change detection by visually comparing historical sidescan sonar imagery (SSI) collected by a sidescan sonar with recently collected SSI in an attempt to identify objects (which might be explosive mines) placed at sea since the last time the area was surveyed. This dissertation presents a data structure and three algorithms, developed by the author, that are part of an automated change detection and classification (ACDC) system. MIW analysts at the Naval Oceanographic Office, to reduce the amount of time to perform change detection, are currently using ACDC. The dissertation introductory chapter gives background information on change detection, ACDC, and describes how SSI is produced from raw sonar data. Chapter 2 presents the author's Geospatial Bitmap (GB) data structure, which is capable of storing information geographically and is utilized by the three algorithms. This chapter shows that a GB data structure used in a polygon-smoothing algorithm ran between 1.3--48.4x faster than a sparse matrix data structure. Chapter 3 describes the GB clustering algorithm, which is the author's repeatable, order-independent method for clustering. Results from tests performed in this chapter show that the time to cluster a set of points is not affected by the distribution or the order of the points. In Chapter 4, the author presents his real-time computer-aided detection (CAD) algorithm that automatically detects mine-like objects on the seafloor in SSI. The author ran his GB-based CAD algorithm on real SSI data, and results of these tests indicate that his real-time CAD algorithm performs comparably to or better than other non-real-time CAD algorithms. The author presents his computer-aided search (CAS) algorithm in Chapter 5. CAS helps MIW analysts locate mine-like features that are geospatially close to previously detected features. A comparison between the CAS and a great circle distance algorithm shows that the

  5. Review of palaeozygopleurid gastropods (Palaeozygopleuridae, Gastropoda) from Devonian strata of the Perunica microplate (Bohemia), with a re-evaluation of their stratigraphic distribution, notes on their ontogeny, and descriptions of new taxa.

    PubMed

    Frýda, Jiři; Ferrová, Lenka; Frýdová, Barbora

    2013-01-01

    Review of all species of the family Palaeozygopleuridae Horný, 1955 (Gastropoda) known from the Perunica microplate (Bohemia) is presented with a description of three new species, Palaeozygopleura lukesi sp. nov., Cimrmaniela sveraki gen. et sp. nov. and Cimrmaniela smoljaki gen. et sp. nov. The stratigraphic distributions of the most of Bohemian palaeozygopleurid species are either corrected or refined, based on new records or modern stratigraphic studies. A complete list of the geographic occurrences of all known palaeozygopleurid gastropods from the Perunica microplate is also given together with notes on their ontogeny.

  6. Classification of Automated Search Traffic

    NASA Astrophysics Data System (ADS)

    Buehrer, Greg; Stokes, Jack W.; Chellapilla, Kumar; Platt, John C.

    As web search providers seek to improve both relevance and response times, they are challenged by the ever-increasing tax of automated search query traffic. Third party systems interact with search engines for a variety of reasons, such as monitoring a web site’s rank, augmenting online games, or possibly to maliciously alter click-through rates. In this paper, we investigate automated traffic (sometimes referred to as bot traffic) in the query stream of a large search engine provider. We define automated traffic as any search query not generated by a human in real time. We first provide examples of different categories of query logs generated by automated means. We then develop many different features that distinguish between queries generated by people searching for information, and those generated by automated processes. We categorize these features into two classes, either an interpretation of the physical model of human interactions, or as behavioral patterns of automated interactions. Using the these detection features, we next classify the query stream using multiple binary classifiers. In addition, a multiclass classifier is then developed to identify subclasses of both normal and automated traffic. An active learning algorithm is used to suggest which user sessions to label to improve the accuracy of the multiclass classifier, while also seeking to discover new classes of automated traffic. Performance analysis are then provided. Finally, the multiclass classifier is used to predict the subclass distribution for the search query stream.

  7. Twelve automated thresholding methods for segmentation of PET images: a phantom study.

    PubMed

    Prieto, Elena; Lecumberri, Pablo; Pagola, Miguel; Gómez, Marisol; Bilbao, Izaskun; Ecay, Margarita; Peñuelas, Iván; Martí-Climent, Josep M

    2012-06-21

    Tumor volume delineation over positron emission tomography (PET) images is of great interest for proper diagnosis and therapy planning. However, standard segmentation techniques (manual or semi-automated) are operator dependent and time consuming while fully automated procedures are cumbersome or require complex mathematical development. The aim of this study was to segment PET images in a fully automated way by implementing a set of 12 automated thresholding algorithms, classical in the fields of optical character recognition, tissue engineering or non-destructive testing images in high-tech structures. Automated thresholding algorithms select a specific threshold for each image without any a priori spatial information of the segmented object or any special calibration of the tomograph, as opposed to usual thresholding methods for PET. Spherical (18)F-filled objects of different volumes were acquired on clinical PET/CT and on a small animal PET scanner, with three different signal-to-background ratios. Images were segmented with 12 automatic thresholding algorithms and results were compared with the standard segmentation reference, a threshold at 42% of the maximum uptake. Ridler and Ramesh thresholding algorithms based on clustering and histogram-shape information, respectively, provided better results that the classical 42%-based threshold (p < 0.05). We have herein demonstrated that fully automated thresholding algorithms can provide better results than classical PET segmentation tools.

  8. Twelve automated thresholding methods for segmentation of PET images: a phantom study

    NASA Astrophysics Data System (ADS)

    Prieto, Elena; Lecumberri, Pablo; Pagola, Miguel; Gómez, Marisol; Bilbao, Izaskun; Ecay, Margarita; Peñuelas, Iván; Martí-Climent, Josep M.

    2012-06-01

    Tumor volume delineation over positron emission tomography (PET) images is of great interest for proper diagnosis and therapy planning. However, standard segmentation techniques (manual or semi-automated) are operator dependent and time consuming while fully automated procedures are cumbersome or require complex mathematical development. The aim of this study was to segment PET images in a fully automated way by implementing a set of 12 automated thresholding algorithms, classical in the fields of optical character recognition, tissue engineering or non-destructive testing images in high-tech structures. Automated thresholding algorithms select a specific threshold for each image without any a priori spatial information of the segmented object or any special calibration of the tomograph, as opposed to usual thresholding methods for PET. Spherical 18F-filled objects of different volumes were acquired on clinical PET/CT and on a small animal PET scanner, with three different signal-to-background ratios. Images were segmented with 12 automatic thresholding algorithms and results were compared with the standard segmentation reference, a threshold at 42% of the maximum uptake. Ridler and Ramesh thresholding algorithms based on clustering and histogram-shape information, respectively, provided better results that the classical 42%-based threshold (p < 0.05). We have herein demonstrated that fully automated thresholding algorithms can provide better results than classical PET segmentation tools.

  9. Laboratory automation: trajectory, technology, and tactics.

    PubMed

    Markin, R S; Whalen, S A

    2000-05-01

    Laboratory automation is in its infancy, following a path parallel to the development of laboratory information systems in the late 1970s and early 1980s. Changes on the horizon in healthcare and clinical laboratory service that affect the delivery of laboratory results include the increasing age of the population in North America, the implementation of the Balanced Budget Act (1997), and the creation of disease management companies. Major technology drivers include outcomes optimization and phenotypically targeted drugs. Constant cost pressures in the clinical laboratory have forced diagnostic manufacturers into less than optimal profitability states. Laboratory automation can be a tool for the improvement of laboratory services and may decrease costs. The key to improvement of laboratory services is implementation of the correct automation technology. The design of this technology should be driven by required functionality. Automation design issues should be centered on the understanding of the laboratory and its relationship to healthcare delivery and the business and operational processes in the clinical laboratory. Automation design philosophy has evolved from a hardware-based approach to a software-based approach. Process control software to support repeat testing, reflex testing, and transportation management, and overall computer-integrated manufacturing approaches to laboratory automation implementation are rapidly expanding areas. It is clear that hardware and software are functionally interdependent and that the interface between the laboratory automation system and the laboratory information system is a key component. The cost-effectiveness of automation solutions suggested by vendors, however, has been difficult to evaluate because the number of automation installations are few and the precision with which operational data have been collected to determine payback is suboptimal. The trend in automation has moved from total laboratory automation to a

  10. The systematic geologic mapping program and a quadrangle-by-quadrangle analysis of time-stratigraphic relations within oil shale-bearing rocks of the Piceance Basin, western Colorado

    USGS Publications Warehouse

    Johnson, Ronald C.

    2012-01-01

    During the 1960s, 1970s, and 1980s, the U.S. Geological Survey mapped the entire area underlain by oil shale of the Eocene Green River Formation in the Piceance Basin of western Colorado. The Piceance Basin contains the largest known oil shale deposit in the world, with an estimated 1.53 trillion barrels of oil in place and as much as 400,000 barrels of oil per acre. This report places the sixty-nine 7½-minute geologic quadrangle maps and one 15-minute quadrangle map published during this period into a comprehensive time-stratigraphic framework based on the alternating rich and lean oil shale zones. The quadrangles are placed in their respective regional positions on one large stratigraphic chart so that tracking the various stratigraphic unit names that have been applied can be followed between adjacent quadrangles. Members of the Green River Formation were defined prior to the detailed mapping, and many inconsistencies and correlation problems had to be addressed as mapping progressed. As a result, some of the geologic units that were defined prior to mapping were modified or discarded. The extensive body of geologic data provided by the detailed quadrangle maps contributes to a better understanding of the distribution and characteristics of the oil shale-bearing rocks across the Piceance Basin.

  11. Automation pilot

    NASA Technical Reports Server (NTRS)

    1983-01-01

    An important concept of the Action Information Management System (AIMS) approach is to evaluate office automation technology in the context of hands on use by technical program managers in the conduct of human acceptance difficulties which may accompany the transition to a significantly changing work environment. The improved productivity and communications which result from application of office automation technology are already well established for general office environments, but benefits unique to NASA are anticipated and these will be explored in detail.

  12. Building a 3D faulted a priori model for stratigraphic inversion: Illustration of a new methodology applied on a North Sea field case study

    NASA Astrophysics Data System (ADS)

    Rainaud, Jean-François; Clochard, Vincent; Delépine, Nicolas; Crabié, Thomas; Poudret, Mathieu; Perrin, Michel; Klein, Emmanuel

    2018-07-01

    Accurate reservoir characterization is needed all along the development of an oil and gas field study. It helps building 3D numerical reservoir simulation models for estimating the original oil and gas volumes in place and for simulating fluid flow behaviors. At a later stage of the field development, reservoir characterization can also help deciding which recovery techniques need to be used for fluids extraction. In complex media, such as faulted reservoirs, flow behavior predictions within volumes close to faults can be a very challenging issue. During the development plan, it is necessary to determine which types of communication exist between faults or which potential barriers exist for fluid flows. The solving of these issues rests on accurate fault characterization. In most cases, faults are not preserved along reservoir characterization workflows. The memory of the interpreted faults from seismic is not kept during seismic inversion and further interpretation of the result. The goal of our study is at first to integrate a 3D fault network as a priori information into a model-based stratigraphic inversion procedure. Secondly, we apply our methodology on a well-known oil and gas case study over a typical North Sea field (UK Northern North Sea) in order to demonstrate its added value for determining reservoir properties. More precisely, the a priori model is composed of several geological units populated by physical attributes, they are extrapolated from well log data following the deposition mode, but usually a priori model building methods respect neither the 3D fault geometry nor the stratification dips on the fault sides. We address this difficulty by applying an efficient flattening method for each stratigraphic unit in our workflow. Even before seismic inversion, the obtained stratigraphic model has been directly used to model synthetic seismic on our case study. Comparisons between synthetic seismic obtained from our 3D fault network model give much

  13. Impacts of variable channel hydraulics on the stratigraphic record: an example provided from the Tullig Sandstone, Western Irish Namurian Basin

    NASA Astrophysics Data System (ADS)

    Wu, C.; Nittrouer, J. A.; Burmeister, K. C.

    2017-12-01

    River hydrodynamic conditions are modified where a system approaches its terminal basin, characterized by the onset of non-uniform "backwater" flow. A decrease in boundary shear stress in the backwater region reduces transport capacity and results in sediment deposition on the channel bed. Although such morphodynamic conditions are common in modern fluvial-deltaic channels, the extent to which these processes are prevalent in the stratigraphic record remains unclear. For example, a few studies documenting changes in fluvial sandstone channel dimensions and grain size distributions near a river terminus attributed this variability to backwater hydrodynamics. However, quantitative tests using morphodynamic models bolstered by a variety of field observations, which could then be linked to sediment depositional patterns and stratigraphy, have yet to be produced. Here we calibrate a one-dimensional river flow model with measurements of paleo-slope and channel depth, and use the output to constrain a sediment transport model, with data from the Tullig Sandstone in the Western Irish Namurian Basin. Based on the model results, our analyses indicate that: (1) backwater hydrodynamics influence the spatial variation of sandstone dimensions and grain size across the delta, and (2) backwater hydrodynamics drive channel bed aggradation and progradation of the river mouth for conditions of constant sea level. Field data indicate that the reach-average story thickness increases, and then decreases, progressing downstream over the backwater reach. Based on the inferred transport and depositional processes, the measured deltaic stratigraphy patterns shown here are assumed to be associated with backwater hydrodynamics, and are therefore largely autogenic in origin. These analyses indicate that non-uniform hydrodynamics can generate stratigraphic patterns that could be conflated as arising due to allogenic effects, based on traditional geometric or diffusion-based depositional models

  14. Automation and robotics technology for intelligent mining systems

    NASA Technical Reports Server (NTRS)

    Welsh, Jeffrey H.

    1989-01-01

    The U.S. Bureau of Mines is approaching the problems of accidents and efficiency in the mining industry through the application of automation and robotics to mining systems. This technology can increase safety by removing workers from hazardous areas of the mines or from performing hazardous tasks. The short-term goal of the Automation and Robotics program is to develop technology that can be implemented in the form of an autonomous mining machine using current continuous mining machine equipment. In the longer term, the goal is to conduct research that will lead to new intelligent mining systems that capitalize on the capabilities of robotics. The Bureau of Mines Automation and Robotics program has been structured to produce the technology required for the short- and long-term goals. The short-term goal of application of automation and robotics to an existing mining machine, resulting in autonomous operation, is expected to be accomplished within five years. Key technology elements required for an autonomous continuous mining machine are well underway and include machine navigation systems, coal-rock interface detectors, machine condition monitoring, and intelligent computer systems. The Bureau of Mines program is described, including status of key technology elements for an autonomous continuous mining machine, the program schedule, and future work. Although the program is directed toward underground mining, much of the technology being developed may have applications for space systems or mining on the Moon or other planets.

  15. Selecting automation for the clinical chemistry laboratory.

    PubMed

    Melanson, Stacy E F; Lindeman, Neal I; Jarolim, Petr

    2007-07-01

    Laboratory automation proposes to improve the quality and efficiency of laboratory operations, and may provide a solution to the quality demands and staff shortages faced by today's clinical laboratories. Several vendors offer automation systems in the United States, with both subtle and obvious differences. Arriving at a decision to automate, and the ensuing evaluation of available products, can be time-consuming and challenging. Although considerable discussion concerning the decision to automate has been published, relatively little attention has been paid to the process of evaluating and selecting automation systems. To outline a process for evaluating and selecting automation systems as a reference for laboratories contemplating laboratory automation. Our Clinical Chemistry Laboratory staff recently evaluated all major laboratory automation systems in the United States, with their respective chemistry and immunochemistry analyzers. Our experience is described and organized according to the selection process, the important considerations in clinical chemistry automation, decisions and implementation, and we give conclusions pertaining to this experience. Including the formation of a committee, workflow analysis, submitting a request for proposal, site visits, and making a final decision, the process of selecting chemistry automation took approximately 14 months. We outline important considerations in automation design, preanalytical processing, analyzer selection, postanalytical storage, and data management. Selecting clinical chemistry laboratory automation is a complex, time-consuming process. Laboratories considering laboratory automation may benefit from the concise overview and narrative and tabular suggestions provided.

  16. 21 CFR 864.5200 - Automated cell counter.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Automated cell counter. 864.5200 Section 864.5200....5200 Automated cell counter. (a) Identification. An automated cell counter is a fully-automated or semi-automated device used to count red blood cells, white blood cells, or blood platelets using a sample of the...

  17. Towards cooperative guidance and control of highly automated vehicles: H-Mode and Conduct-by-Wire.

    PubMed

    Flemisch, Frank Ole; Bengler, Klaus; Bubb, Heiner; Winner, Hermann; Bruder, Ralph

    2014-01-01

    This article provides a general ergonomic framework of cooperative guidance and control for vehicles with an emphasis on the cooperation between a human and a highly automated vehicle. In the twenty-first century, mobility and automation technologies are increasingly fused. In the sky, highly automated aircraft are flying with a high safety record. On the ground, a variety of driver assistance systems are being developed, and highly automated vehicles with increasingly autonomous capabilities are becoming possible. Human-centred automation has paved the way for a better cooperation between automation and humans. How can these highly automated systems be structured so that they can be easily understood, how will they cooperate with the human? The presented research was conducted using the methods of iterative build-up and refinement of framework by triangulation, i.e. by instantiating and testing the framework with at least two derived concepts and prototypes. This article sketches a general, conceptual ergonomic framework of cooperative guidance and control of highly automated vehicles, two concepts derived from the framework, prototypes and pilot data. Cooperation is exemplified in a list of aspects and related to levels of the driving task. With the concept 'Conduct-by-Wire', cooperation happens mainly on the guidance level, where the driver can delegate manoeuvres to the automation with a specialised manoeuvre interface. With H-Mode, a haptic-multimodal interaction with highly automated vehicles based on the H(orse)-Metaphor, cooperation is mainly done on guidance and control with a haptically active interface. Cooperativeness should be a key aspect for future human-automation systems. Especially for highly automated vehicles, cooperative guidance and control is a research direction with already promising concepts and prototypes that should be further explored. The application of the presented approach is every human-machine system that moves and includes high

  18. The Ufa indenter: stratigraphic and geophysic evidences for an actual indentation of the Southern Urals by the East European craton

    NASA Astrophysics Data System (ADS)

    Lefort, Jean-Pierre; Danukalova, Guzel

    2014-07-01

    Study of the altitudes of the lowest part of the Upper Cretaceous-Eocene and Aktschagylian-Quaternary stratigraphic ensembles known on the western slope of the Southern Urals evidences the existence of an East-West elongated dome which follows the N53° latitude. This ridge is superimposed at depth with the remnants of the Sernovodsk-Abdulino Aulacogen and with the Belaya tear fault, which support the existence of a recent rejuvenation of these old structures. North of these disruptions the Southern Urals display a clear bent towards the East. Detailed microstructural studies show that this curvature is associated with a typical stress pattern which suggests the existence of an indentation of the fold belt by the East European craton. The hypothesis of an Ufa indenter is not supported by an equivalent East-West deep fault north of the bend. However, a long N100° magnetic anomaly, interpreted as a shear zone, suggests that the indenter is a reality. Quaternary uplift and crustal thickening at its front as well as seismological data support our interpretation. It is not stressed that the curvature of the Urals observed at 56° latitude results solely from this recent indentation. It is only assumed that the actual indentation is rejuvenating a former unevenness which existed before in the East European craton. Study of the inner part of the indenter shows that this type of structure is not necessarily rigid and undeformed. Some of the structures described on the URSEIS deep seismic line could be much younger than previously expected.

  19. Taxonomic revision and stratigraphic provenance of 'Histiophorus rotundu' Woodward 1901 (Teleostei, Perciformes)

    USGS Publications Warehouse

    Monsch, K.A.; Fierstine, H.L.; Weems, R.E.

    2005-01-01

    Until recently, Histiophorus rotundus Woodward 1901, was known from a single, poorly preserved rostrum from the Tertiary phosphate beds near Charleston, South Carolina, an area from which many fossils have been described. The specimen is relatively featureless externally; its internal anatomy is unknown and the documentation of its geological provenance was poor. In an earlier revision the species was transferred to the fossil billfish genus Xiphiorhynchus Van Beneden, 1871. Here we confirm this designation, supported by new morphological studies of the holotype, recently found specimens of Xiphiorhynchus rotundus (Woodward, 1901), and the stratigraphic record of Xiphiorhynchus. The systematic paleontology we present is a contribution to the taxonomic revision of billfishes world-wide. Because the holotype is heavily phosphatized and the type locality was vaguely described, we discuss the geology of the phosphate mining districts of the Charleston region. Based on our studies, we can narrow the possible age of the holotype to late Oligocene or early Miocene. We suggest X. rotundus was extinct by the Burdigalian. 

  20. Horizontal drilling in the Austin Chalk: Stratigraphic factors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Durham, C.O. Jr.; Bobigian, R.A.

    1990-05-01

    Horizontal drilling has renewed interest in the Austin chalk in south-central Texas. Large fields on opposite sides of the San Marcos arch Giddings to the northeast and Pearsall to the southwest were active with vertical drilling 10 years ago. Giddings' 4,500 Austin wells produced 209 million BO and 934 bcfg of gas through 1988; Pearsall's 1,440 wells produced 57 million BO and 35 bcfg of gas. Most vertical wells were completed, 20% were economic successes, 40% were marginal, 40% were uneconomic due to uneven areal distribution of near-vertical fractures and small faults, which provide reservoirs in otherwise tight chalk. Horizontalmore » drilling, led by Amoco in Giddings and Oryx in Pearsall, enhances the chances of encountering the fractures by drilling perpendicular to the fracture trend. Horizontal drilling requires preselection of the stratigraphic horizon to be penetrated. One must understand the variable Austin stratigraphy to choose the zone with the most brittle character and best matrix porosity, both reduced by increased clay content. Chalk 130 ft thick on the San Marcos arch thickens to 600 to 800 ft in central Giddings field where middle marl separates lower and upper chalk Northeastward only lower chalk is preserved beneath a post-Austin submarine channel. The Austin thickens to 300-500 ft in Pearsall field where middle member ash beds separate lower and upper chalk inhibiting vertical reservoir communication. Locally, on the Pearsall arch, ash is missing, lower chalk thickens, and upper chalk thins.« less