Sample records for average background values

  1. Importance of background values in assessing the impact of heavy metals in river ecosystems: case study of Tisza River, Serbia.

    PubMed

    Štrbac, Snežana; Kašanin Grubin, Milica; Vasić, Nebojša

    2017-11-30

    The main objective of this paper is to evaluate how a choice of different background values may affect assessing the anthropogenic heavy metal pollution in sediments from Tisza River (Serbia). The second objective of this paper is to underline significance of using geochemical background values when establishing quality criteria for sediment. Enrichment factor (EF), geoaccumulation index (I geo ), pollution load index (PLI), and potential ecological risk index (PERI) were calculated using different background values. Three geochemical (average metal concentrations in continental crust, average metal concentrations in shale, and average metal concentrations in non-contaminated core sediment samples) and two statistical methods (delineation method and principal component analyses) were used for calculating background values. It can be concluded that obtained information of pollution status can be more dependent on the use of background values than the index/factor chosen. The best option to assess the potential river sediment contamination is to compare obtained concentrations of analyzed elements with concentrations of mineralogically and texturally comparable, uncontaminated core sediment samples. Geochemical background values should be taken into account when establishing quality criteria for soils, sediments, and waters. Due to complexity of the local lithology, it is recommended that environmental monitoring and assessment include selection of an appropriate background values to gain understanding of the geochemistry and potential source of pollution in a given environment.

  2. Background radiation in the Albuquerque, New Mexico, U.S.A., area

    NASA Astrophysics Data System (ADS)

    Brookins, Douglas G.

    1992-01-01

    Background radiation levels in the Albuquerque, New Mexico, area are elevated when compared to much of the United States. Soil K, U, and Th are somewhat elevated compared to average values in this country and generate roughly 60 mrem per year to the average resident. Cosmic ray contribution, due to the mean elevation of 5,200 ft above sea level, is 80 mrem/yr—well over the average for the United States. Thirty percent of the homes in Albuquerque contain indoor radon levels over the EPA action level of 4 pCi/ℓ compared to 10 12 percent of homes for the entire United States. Indoor radon contributes about 100 300 mrem/yr. Food, beverages, and x-ray doses are assumed at an average-equivalent for the United States and locally yield 96 mrem/yr. Total contributions from other minor sources (color TV, coal, weapons fallout, etc.) are under 10 mrem/yr. Thus total background radiation received by Albuquerque residents is about 330 530 mrem/yr, well in excess of the rest of the United States. The spread in mrem values is due to variations in the contribution from indoor radon.

  3. Ozone and its projection in regard to climate change

    NASA Astrophysics Data System (ADS)

    Melkonyan, Ani; Wagner, Patrick

    2013-03-01

    In this paper, the dependence of ozone-forming potential on temperature was analysed based on data from two stations (with an industrial and rural background, respectively) in North Rhine-Westphalia, Germany, for the period of 1983-2007. After examining the interrelations between ozone, NOx and temperature, a projection of the days with ozone exceedance (over a limit value of a daily maximum 8-h average ≥ 120 μg m-3 for 25 days per year averaged for 3 years) in terms of global climate change was made using probability theory and an autoregression integrated moving average (ARIMA) model. The results show that with a temperature increase of 3 K, the frequency of days when ozone exceeds its limit value will increase by 135% at the industrial station and by 87% at the rural background station.

  4. Regional and local background ozone in Houston during Texas Air Quality Study 2006

    NASA Astrophysics Data System (ADS)

    Langford, A. O.; Senff, C. J.; Banta, R. M.; Hardesty, R. M.; Alvarez, R. J.; Sandberg, Scott P.; Darby, Lisa S.

    2009-04-01

    Principal Component Analysis (PCA) is used to isolate the common modes of behavior in the daily maximum 8-h average ozone mixing ratios measured at 30 Continuous Ambient Monitoring Stations in the Houston-Galveston-Brazoria area during the Second Texas Air Quality Study field intensive (1 August to 15 October 2006). Three principal components suffice to explain 93% of the total variance. Nearly 84% is explained by the first component, which is attributed to changes in the "regional background" determined primarily by the large-scale winds. The second component (6%) is attributed to changes in the "local background," that is, ozone photochemically produced in the Houston area and spatially and temporally averaged by local circulations. Finally, the third component (3.5%) is attributed to short-lived plumes containing high ozone originating from industrial areas along Galveston Bay and the Houston Ship Channel. Regional background ozone concentrations derived using the first component compare well with mean ozone concentrations measured above the Gulf of Mexico by the tunable profiler for aerosols and ozone lidar aboard the NOAA Twin Otter. The PCA regional background values also agree well with background values derived using the lowest daily 8-h maximum method of Nielsen-Gammon et al. (2005), provided the Galveston Airport data (C34) are omitted from that analysis. The differences found when Galveston is included are caused by the sea breeze, which depresses ozone at Galveston relative to sites further inland. PCA removes the effects of this and other local circulations to obtain a regional background value representative of the greater Houston area.

  5. Weighed scalar averaging in LTB dust models: part II. A formalism of exact perturbations

    NASA Astrophysics Data System (ADS)

    Sussman, Roberto A.

    2013-03-01

    We examine the exact perturbations that arise from the q-average formalism that was applied in the preceding article (part I) to Lemaître-Tolman-Bondi (LTB) models. By introducing an initial value parametrization, we show that all LTB scalars that take an FLRW ‘look-alike’ form (frequently used in the literature dealing with LTB models) follow as q-averages of covariant scalars that are common to FLRW models. These q-scalars determine for every averaging domain a unique FLRW background state through Darmois matching conditions at the domain boundary, though the definition of this background does not require an actual matching with an FLRW region (Swiss cheese-type models). Local perturbations describe the deviation from the FLRW background state through the local gradients of covariant scalars at the boundary of every comoving domain, while non-local perturbations do so in terms of the intuitive notion of a ‘contrast’ of local scalars with respect to FLRW reference values that emerge from q-averages assigned to the whole domain or the whole time slice in the asymptotic limit. We derive fluid flow evolution equations that completely determine the dynamics of the models in terms of the q-scalars and both types of perturbations. A rigorous formalism of exact spherical nonlinear perturbations is defined over the FLRW background state associated with the q-scalars, recovering the standard results of linear perturbation theory in the appropriate limit. We examine the notion of the amplitude and illustrate the differences between local and non-local perturbations by qualitative diagrams and through an example of a cosmic density void that follows from the numeric solution of the evolution equations.

  6. Measurement of 226Ra, 232Th, 137Cs and 40K activities of Wheat and Corn Products in Ilam Province – Iran and Resultant Annual Ingestion Radiation Dose

    PubMed Central

    CHANGIZI, Vahid; SHAFIEI, Elham; ZAREH, Mohammad Reza

    2013-01-01

    Background: Background: Natural background radiation is the main source of human exposure to radioactive material. Soils naturally have radioactive mineral contents. The aim of this study is to determine natural (238 U, 232 Th, 40 K) and artificial (137 Cs) radioactivity levels in wheat and corn fields of Eilam province. Methods: HPGe detector was used to measure the concentration activity of 238 U and 232 Th series, 40 K and 137 Cs in wheat and corn samples taken from different regions of Eilam province, in Iran. Results: In wheat and corn samples, the average activity concentrations of 226 Ra, 232 Th, 40 K and 137 Cs were found to be 1, 67, 0.5, 91.73, 0.01 and 0.81, 0.85, 101.52, 0.07 Bq/kg (dry weight), respectively. H ex and H in in the present work are lower than 1. The average value of H ex was found to be 0.02 and 0.025 and average value of H in to be found 0.025 and 0.027 in wheat fields samples and corn samples in Eilam provinces, respectively. The obtained values of AGDE are 30.49 mSv/yr for wheat filed samples and 37.89 mSv/yr for corn samples; the AEDE rate values are 5.28 mSv/yr in wheat filed samples and this average value was found to be 6.13 mSv/yr in corn samples in Eilam. Transfer factors (TFs) of long lived radionuclide such as 137 Cs, 226 Ra, 232 Th and 40 K from soils to corn and wheat plants have been studied by radiotracer experiments. Conclusion: The natural radioactivity levels in Eilam province are not at the range of high risk of morbidity and are under international standards. PMID:26056646

  7. Background estimation and player detection in badminton video clips using histogram of pixel values along temporal dimension

    NASA Astrophysics Data System (ADS)

    Peng, Yahui; Ma, Xiao; Gao, Xinyu; Zhou, Fangxu

    2015-12-01

    Computer vision is an important tool for sports video processing. However, its application in badminton match analysis is very limited. In this study, we proposed a straightforward but robust histogram-based background estimation and player detection methods for badminton video clips, and compared the results with the naive averaging method and the mixture of Gaussians methods, respectively. The proposed method yielded better background estimation results than the naive averaging method and more accurate player detection results than the mixture of Gaussians player detection method. The preliminary results indicated that the proposed histogram-based method could estimate the background and extract the players accurately. We conclude that the proposed method can be used for badminton player tracking and further studies are warranted for automated match analysis.

  8. Application of tristimulus colorimetry to estimate the carotenoids content in ultrafrozen orange juices.

    PubMed

    Meléndez-Martínez, Antonio J; Vicario, Isabel M; Heredia, Francisco J

    2003-12-03

    Tristimulus Colorimetry was applied to characterize the color of Valencia late orange juices. Color measurements were made against white background and black background. The profile of the main carotenoids related to the color of the juices was determined by HPLC. Significant correlations (p < 0.05) between b*, Cab* and h(ab) and the content of beta-cryptoxanthin, lutein + zeaxanthin and beta-carotene were found. The correlations between the color parameters L*, a*, b*, Cab* and h(ab) and the carotenoids content were also explored by partial least squares. The results obtained have shown that it is possible to obtain equations, by means of multiple regression models, which allow the determination of the individual carotenoid levels from the CIELAB color parameters, with R2 values always over 0.9. In this sense, equations have been proposed to calculate the retinol equivalents (1 RE = 1 microgram retinol = 12 micrograms beta-carotene = 24 micrograms alpha-carotene = 24 micrograms beta-cryptoxanthin) of the orange juice analyzed as a function of the color parameters calculated from measurement made against white and black backgrounds. The average RE per liter of juice obtained by HPLC was 51.07 +/- 18.89, whereas employing these equations, average RE values obtained were 51.16 +/- 1.36 and 51.21 +/- 1.70 for white background and black background, respectively.

  9. Evaluation of external and internal irradiation on uranium mining enterprise staff by tooth enamel EPR spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhumadilov, Kassym; Ivannikov, Alexander; Khailov, Artem; Orlenko, Sergei; Skvortsov, Valeriy; Stepanenko, Valeriy; Kuterbekov, Kairat; Toyoda, Shin; Kazymbet, Polat; Hoshi, Masaharu

    2017-11-01

    In order to estimate radiation effects on uranium enterprise staff and population teeth samples were collected for EPR tooth enamel dosimetry from population of Stepnogorsk city and staff of uranium mining enterprise in Shantobe settlment (Akmola region, North of Kazakhstan). By measurements of tooth enamel EPR spectra, the total absorbed dose in the enamel samples and added doses after subtraction of the contribution of natural background radiation are determined. For the population of Stepnogorsk city average added dose value of 4 +/- 11 mGy with variation of 51 mGy was obtained. For the staff of uranium mining enterprise in Shantobe settlment average value of added dose 95 +/- 20 mGy, with 85 mGy variation was obtained. Higher doses and the average value and a large variation for the staff, probably is due to the contribution of occupational exposure.

  10. Biological activity of soddy-calcareous soils and cultural layers in Alanian settlements of the Kislovodsk basin

    NASA Astrophysics Data System (ADS)

    Chernysheva, E. V.; Kashirskaya, N. N.; Korobov, D. S.; Borisov, A. V.

    2014-09-01

    Microbiological investigations of cultural layers were performed in a settlement of the Alanian culture—Podkumskoe-2 (the 2nd-4th centuries AD). The present-day soddy-calcareous soils (rendzinas) used for different purposes were also studied near this settlement. The most significant changes in the initial characteristics of the soil microbial communities occurred under the residential influence more than 1500 years ago; these changes have been preserved until the present time. In the areas subjected to the anthropogenic impact, the total microbial biomass (the weighted average of 3720 μg C/g soil) was lower than that in the background soil. The minimal values of the microbial biomass were found in the soil of the pasture—2.5 times less than in the background soil. The urease activity of the cultural layer was higher than that of the soils nearby the settlement. Elevated values of the cellulose activity were also recorded only in the cultural layers. The current plowing has led to a significant decrease in the mycelium biomass of the microscopic fungi. In the soil of the fallow, the weighted average value of the fungal hyphae biomass along the profile was twice lower than that in the background soil and cultural layers of the settlement. The pasture first affected the active microbial biomass and, to a lesser extent, the amount of microscopic fungi.

  11. Human response to high-background radiation environments on Earth and in space

    NASA Astrophysics Data System (ADS)

    Durante, M.; Manti, L.

    The main long-term goal of the space exploration program is the colonization of the planets of the Solar System The high cosmic radiation equivalent dose rate represents a major problem for a stable and safe colonization of the planets The dose rate on Mars ranges between 60 and 150 mSv year depending on the Solar cycle and altitude and can reach values as high as 360 mSv year on the Moon The average dose rate on the Earth is about 3 mSv year reduced to about 1 mSv year excluding the internal exposure to Rn daughters However some areas of the Earth have anomalously high levels of background radiation Values 200-400 times higher than the world average are found in regions where monazite sand deposits are abundant Population in Tibet experience a high cosmic radiation background Epidemiological studies did not detect any adverse health effects in the populations living in those high-background radiation areas on Earth Chromosomal aberrations in the peripheral blood lymphocytes from the population living in the high-background radiation areas have been measured in several studies because the chromosomal damage represents an early biomarker of cancer risk Similar cytogenetic studies have been recently performed in cohort of astronauts involved in single or repeated space flights over many years A comparison of the cytogenetic findings in populations exposed at high dose rate on Earth or in space will be described

  12. Geochemical background of zinc, cadmium and mercury in anthropically influenced soils in a semi-arid zone (SE, Spain)

    NASA Astrophysics Data System (ADS)

    García-Lorenzo, M. L.; Pérez-Sirvent, C.; Martínez-Sánchez, M. J.; Molina, J.; Tudela, M. L.; Hernández-Córdoba, M.

    2009-04-01

    This work seeks to establish the geochemical background for three potentially toxic trace elements (Zn, Cd and Hg) in a pilot zone included in the DesertNet project in the province of Murcia. The studied area, known as Campo de Cartagena, Murcia (SE Spain) is an area of intensive agriculture and has been much affected over the years by anthropic activity. The zone can be considered an experimental pilot zone for establishing background levels in agricultural soils. Sixty four samples were collected and corresponded to areas subjected to high and similar agricultural activity or soils with natural vegetation, which correspond to abandoned agricultural areas. The Zn content was determined by flame atomic absorption spectrometry. The Cd content was determined by electrothermal atomization atomic absorption spectrometry and mercury content was determined by atomic fluorescence spectrometry. Geostatistical analysis consisting of kriging and mapping was performed using the geostatistical analyst extension of ArcGIS 8.3. Zinc values ranged from 10 mg kg-1 to 151 mg kg-1, with an average value of 45 mg kg-1. Cadmium values ranged between 0.1 mg kg-1 and 0.9mg kg-1, with a mean value of 0.3 mg kg-1 and mercury values ranged from 0.1 mg kg-1 to 2.3 mg kg-1, with a mean value of 0.5 mg kg-1. At a national level, the Spanish Royal Decree 9/2005 proposes toxicological and statistical approaches to establish background values. According to the statistical approach, background values consist of the median value for the selected element. The background values for Zn, Cd and Hg in the studied area were 40 mg kg-1 for Zn, 0.3 mg kg-1 for Cd and 0.4 mg kg-1 for Hg.

  13. Public exposure due to external gamma background radiation in boundary areas of Iran.

    PubMed

    Pooya, S M Hosseini; Dashtipour, M R; Enferadi, A; Orouji, T

    2015-09-01

    A monitoring program in boundary areas of a country is an appropriate way to indicate the level of public exposure. In this research, gamma background radiation was measured using TL dosimeters at 12 boundary areas as well as in the capital city of Iran during the period 2010 to 2011. The measurements were carried out in semi-annual time intervals from January to June and July to December in each year. The maximum average dose equivalent value measured was approximately 70 μSv/month for Tehran city. Also, the average dose values obtained were less than 40 μSv/month for all the cities located at the sea level except that of high level natural radiation area of Ramsar, and more than 55 μSv/month for the higher elevation cities. The public exposure due to ambient gamma dose equivalent in Iran is within the levels reported by UNSCEAR. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. SAGE aerosol measurements. Volume 3: January 1, 1981 to November 18, 1981

    NASA Technical Reports Server (NTRS)

    Mccormick, M. Patrick

    1987-01-01

    The Stratospheric Aerosol and Gas Experiment (SAGE) satellite system, launched February 18, 1979, obtained profiles of aerosol extinction at 1.00 micron and 0.45 micron ozone concentration, and nitrogen dioxide concentration. Data taken during sunset events are presented in the form of zonal and seasonal averages of aerosol extinction of 1.00 micron and 0.45 micron, ratios of aerosol extinction to molecular extinction at 1.00 micron and ratios of aerosol extinction at 0.45 micron to aerosol extinction at 1.00 micron. Averages for 1981 are shown in tables, and in profile and contour plots (as a function of altitude and latitude). In addition, temperature data provided by NOAA for the time and location of each SAGE measurement are averaged and shown in a similar format. The stratospheric aerosol distribution for 1981 shows effects of volcanically injected material from eruptions of Ulawun, Alaid, and Pagan. Peak values of aerosol extinction at 0.45 micron and 1.00 micron were 2 to 4 times higher than typical peak values observed during near background conditions. Stratospheric aerosol optical depth values at 1.00 microns increased by a factor of about 2 from near background levels in regions of volcanic activity. During the year, these values ranged from between 0.001 and 0.006. The largest were near the location of a recent eruption. The distribution of the ratio of aerosol to molecular extinction at 1.00 microns also showed that maximum values are found in the vicinity of an eruption. These maximums varied in altitude, but remained below a height of about 25 km. No attempt has been made to give detailed explanations or interpretations of these data. The intent is to provide, in a ready-to-use visual format, representative zonal and seasonal averages of aerosol extinction data for the third calendar year of the SAGE data set to facilitate atmospheric and climatic studies.

  15. Style-by-style analysis of two sporadic self-compatible Solanum chacoense lines supports a primary role for S-RNases in determining pollen rejection thresholds.

    PubMed

    Qin, Xike; Liu, Bolin; Soulard, Jonathan; Morse, David; Cappadocia, Mario

    2006-01-01

    A method for the quantification of S-RNase levels in single styles of self-incompatible Solanum chacoense was developed and applied toward an experimental determination of the S-RNase threshold required for pollen rejection. It was found that, when single style values are averaged, accumulated levels of the S(11)- and S(12)-RNases can differ up to 10-fold within a genotype, while accumulated levels of the S(12)-RNase can differ by over 3-fold when different genotypes are compared. Surprisingly, the amount of S(12)-RNase accumulated in different styles of the same plant can differ by over 20-fold. A low level of 160 ng S-RNase in individual styles of fully incompatible plants, and a high value of 68 ng in a sporadic self-compatible (SSC) line during a bout of complete compatibility was measured, suggesting that these values bracket the threshold level of S-RNase needed for pollen rejection. Remarkably, correlations of S-RNase values to average fruit sets in different plant lines displaying sporadic self-compatibility (SSC) to different extents as well as to fruit set in immature flowers, are all consistent with a threshold value of 80 ng S(12)-RNase. Taken together, these results suggest that S-RNase levels alone are the principal determinant of the incompatibility phenotype. Interestingly, while the S-RNase threshold required for rejection of S(12)-pollen from a given genetic background is the same in styles of different genetic backgrounds, it is different when pollen donors of different genetic backgrounds are used. These results reveal a previously unsuspected level of complexity in the incompatibility reaction.

  16. Background radiation: natural and man-made.

    PubMed

    Thorne, M C

    2003-03-01

    A brief overview and comparison is given of dose rates arising from natural background radiation and the fallout from atmospheric testing of nuclear weapons. Although there are considerable spatial variations in exposure to natural background radiation, it is useful to give estimates of worldwide average overall exposures from the various components of that background. Cosmic-ray secondaries of low linear energy transfer (LET), mainly muons and photons, deliver about 280 microSv a(-1). Cosmic-ray neutrons deliver about another 100 microSv a(-1). These low- and high-LET exposures are relatively uniform to the whole body. The effective dose rate from cosmogenic radionuclides is dominated by the contribution of 12 microSv a(-1) from 14C. This is due to relatively uniform irradiation of all organs and tissues from low-energy beta particles. Primordial radionuclides and their progeny (principally the 238U and 232Th series, and 40K) contribute about 480 microSv a(-1) of effective dose by external irradiation. This is relatively uniform photon irradiation of the whole body. Internally incorporated 40K contributes a further 165 microSv a(-1) of effective dose in adults, mainly from beta particles, but with a significant gamma component. Equivalent doses from 40K are somewhat higher in muscle than other soft tissues, but the distinction is less than a factor of three. Uranium and thorium series radionuclides give rise to an average effective dose rate of around 120 microSv a(-1). This includes a major alpha particle component, and exposures of radiosensitive tissues in lung, liver, kidney and the skeleton are recognised as important contributors to effective dose. Overall, these various sources give a worldwide average effective dose rate of about 1160 microSv a(-1). Exposure to 222Rn, 220Rn and their short-lived progeny has to be considered separately. This is very variable both within and between countries. For 222Rn and its progeny, a worldwide average effective dose rate is about 1105 microSv a(-1). For 220Rn and its progeny, the corresponding value is 91 microSv a(-1). In both cases, the effective dose is mainly due to a particle irradiation of the bronchial tissues of the lungs. Overall, the worldwide average effective dose rate from natural background is about 2400 microSv a(-1) or 2.4 mSv a(-1). For comparison, worldwide average effective dose rates from weapons fallout peaked at 113 microSv a(-1) (about 5% of natural background) in 1963 and have since fallen to about 5.5 microSv a(-1) (about 0.2% of natural background). These values perhaps serve to emphasise that even gross insults to the natural environment from anthropogenic releases of radioactive materials are likely to be of limited significance when set in the context of the ambient radioactive environment within which all organisms, including humans, have developed.

  17. Aerosol optical properties observation and its relationship to meteorological conditions and emission during the Chinese National Day and Spring Festival holiday in Beijing

    NASA Astrophysics Data System (ADS)

    Zheng, Yu; Che, Huizheng; Zhao, Tianliang; Zhao, Hujia; Gui, Ke; Sun, Tianze; An, Linchang; Yu, Jie; Liu, Chong; Jiang, Yongcheng; Zhang, Lei; Wang, Hong; Wang, Yaqiang; Zhang, Xiaoye

    2017-11-01

    The reduction of traffic flow in downtown areas during the Chinese National Day holiday and the fireworks during the Spring Festival provide a unique opportunity for investigating the impact of urban anthropogenic activities on aerosol optical properties during these important Chinese festivals in Beijing. The National Day in 2014 and 2015 and Spring Festival in 2015 and 2016 were selected as study periods. The aerosol optical depth (AOD) at 440 nm increased over the all holiday periods and the average AODs during the 2015 National Day, 2015 Spring Festival and 2016 Spring Festival were about 81%, 21% and 36% higher than the background levels, respectively. The average AOD in 2014 National Day holiday was lower than background level partly influenced by precipitation event. The absorption AOD (AAOD) at 440 nm showed consistent variations with the AOD and the average AAODs during the 2015 National Day, 2015 Spring Festival and 2016 Spring Festival holidays were about 75%, 19% and 23% higher than the background level, respectively. The mean values of single scattering albedo were greater than the background level during the Spring Festival holidays, whereas the values during the National Day holiday in 2015 were lower partly due to the reduction of vehicular emissions in downtown areas. Fine- and coarse-mode particle volumes during pollution periods in holidays were 0.04-0.25 μm3 and 0.03-0.15 μm3 larger than background level, respectively. The results of potential source contribution function and concentration-weighted trajectory analyses identified the areas south of Beijing as the main source regions of PM2.5 and were responsible for the extremely high PM2.5 concentrations in Beijing during the holiday periods. The findings of this study may aid understanding the effects of human activities on aerosol optical properties over Beijing area and contribute to improving regional air quality.

  18. Chemical fractionation and mobility of traffic-related elements in road environments.

    PubMed

    Adamiec, Ewa

    2017-12-01

    Due to considerable progress in exhaust control emission technology and extensive regulatory work regarding this issue, non-exhaust sources of air pollution have become a growing concern. This research involved studying three types of road environment samples such as road dust, sludge from storm drains and roadside soil collected from heavily congested and polluted cities in Poland (Krakow, Warszawa, Opole and Wroclaw). Particles below 20 µm were examined since it was previously estimated that this fine fraction of road dust is polluted mostly by metals derived from non-exhaust sources of pollution such as brake linings wear. Chemical analysis of all samples was combined with a fractionation study using BCR protocol. It was concluded that the finest fractions of road environment samples were significantly contaminated with all of the investigated metals, in particular with Zn, Cu, both well-known key tracers of brake and tire wear. In Warszawa, the pollution index for Zn was on average 15-18 times the background value, in Krakow 12 times, in Wroclaw 8-12 times and in Opole 6-9 times the background value. The pollution index for Cu was on average 6-14 times the background in Warszawa, 7-8 times in Krakow, 4-6 times in Wroclaw and in Opole 5 times the background value. Fractionation study revealed that mobility of examined metals decreases in that order: Zn (43-62%) > Cd (25-42%) > Ni (6-16%) > Cu (3-14%) > Pb (1-8%). It should, however, be noted that metals even when not mobile in the environment can become a serious health concern when ingested or inhaled.

  19. Modeling particle number concentrations along Interstate 10 in El Paso, Texas

    PubMed Central

    Olvera, Hector A.; Jimenez, Omar; Provencio-Vasquez, Elias

    2014-01-01

    Annual average daily particle number concentrations around a highway were estimated with an atmospheric dispersion model and a land use regression model. The dispersion model was used to estimate particle concentrations along Interstate 10 at 98 locations within El Paso, Texas. This model employed annual averaged wind speed and annual average daily traffic counts as inputs. A land use regression model with vehicle kilometers traveled as the predictor variable was used to estimate local background concentrations away from the highway to adjust the near-highway concentration estimates. Estimated particle number concentrations ranged between 9.8 × 103 particles/cc and 1.3 × 105 particles/cc, and averaged 2.5 × 104 particles/cc (SE 421.0). Estimates were compared against values measured at seven sites located along I10 throughout the region. The average fractional error was 6% and ranged between -1% and -13% across sites. The largest bias of -13% was observed at a semi-rural site where traffic was lowest. The average bias amongst urban sites was 5%. The accuracy of the estimates depended primarily on the emission factor and the adjustment to local background conditions. An emission factor of 1.63 × 1014 particles/veh-km was based on a value proposed in the literature and adjusted with local measurements. The integration of the two modeling techniques ensured that the particle number concentrations estimates captured the impact of traffic along both the highway and arterial roadways. The performance and economical aspects of the two modeling techniques used in this study shows that producing particle concentration surfaces along major roadways would be feasible in urban regions where traffic and meteorological data are readily available. PMID:25313294

  20. Background Conditions for the October 29, 2003 Solar Flare by the AVS-F Apparatus Data

    NASA Astrophysics Data System (ADS)

    Arkhangelskaja, I. V.; Arkhangelskiy, A. I.; Lyapin, A. R.; Troitskaya, E. V.

    The background model for AVS-F apparatus onboard CORONAS-F satellite for the October 29, 2003 X10-class solar flare is discussed in the presented work. This background model developed for AVS-F counts rate in the low- and high-energy spectral ranges in both individual channels and summarized. Count rate were approximated by polynomials of high order taking into account the mean count rate in the geomagnetic equatorial region at the different orbits parts and Kp-index averaged on 5 bins in time interval from -24 to -12 hours before the time of geomagnetic equator passing. The observed averaged counts rate on equator in the region of geomagnetic latitude ±5o and estimated minimum count rate values are in coincidence within statistical errors for all selected orbits parts used for background modeling. This model will used to refine the estimated energy of registered during the solar flare spectral features and detailed analysis of their temporal profiles behavior both in corresponding energy bands and in summarized energy range.

  1. Assessment of natural background radiation in one of the highest regions of Ecuador

    NASA Astrophysics Data System (ADS)

    Pérez, Mario; Chávez, Estefanía; Echeverría, Magdy; Córdova, Rafael; Recalde, Celso

    2018-05-01

    Natural background radiation was measured in the province of Chimborazo (Ecuador) with the following reference coordinates 1°40'00''S 78°39'00''W, where the furthest point to the center of the planet is located. Natural background radiation measurements were performed at 130 randomly selected sites using a Geiger Müller GCA-07W portable detector; these measurements were run at 6 m away from buildings or walls and 1 m above the ground. The global average natural background radiation established by UNSCEAR is 2.4 mSv y-1. In the study area measurements ranged from 0.57 mSv y-1 to 3.09 mSv y-1 with a mean value of 1.57 mSv y-1, the maximum value was recorded in the north of the study area at 5073 metres above sea level (m.a.s.l.), and the minimum value was recorded in the southwestern area at 297 m.a.s.l. An isodose map was plotted to represent the equivalent dose rate due to natural background radiation. An analysis of variance (ANOVA) between the data of the high and low regions of the study area showed a significant difference (p < α), in addition a linear correlation coefficient of 0.92 was obtained, supporting the hypothesis that in high altitude zones extraterrestrial radiation contributes significantly to natural background radiation.

  2. Radionuclides and Radiation Indices of High Background Radiation Area in Chavara-Neendakara Placer Deposits (Kerala, India)

    PubMed Central

    Derin, Mary Thomas; Vijayagopal, Perumal; Venkatraman, Balasubramaniam; Chaubey, Ramesh Chandra; Gopinathan, Anilkumar

    2012-01-01

    The present paper describes a detailed study on the distribution of radionuclides along Chavara – Neendakara placer deposit, a high background radiation area (HBRA) along the Southwest coast of India (Kerala). Judged from our studies using HPGe gamma spectrometric detector, it becomes evident that Uranium (238U), Thorium (232Th) and Potassium (40K) are the major sources for radioactivity prevailing in the area. Our statistical analyses reveal the existence of a high positive correlation between 238U and 232Th, implicating that the levels of these elements are interdependent. Our SEM-EDAX analyses reveal that titanium (Ti) and zircon (Zr) are the major trace elements in the sand samples, followed by aluminum, copper, iron, ruthenium, magnesium, calcium, sulphur and lead. This is first of its kind report on the radiation hazard indices on this placer deposit. The average absorbed dose rates (9795 nGy h−1) computed from the present study is comparable with the top-ranking HBRAs in the world, thus offering the Chavara-Neendakara placer the second position, after Brazil; pertinently, this value is much higher than the World average. The perceptibly high absorbed gamma dose rates, entrained with the high annual external effective dose rates (AEED) and average annual gonadal dose equivalent (AGDE) values existing in this HBRA, encourage us to suggest for a candid assessment of the impact of the background radiation, if any, on the organisms that inhabit along this placer deposit. Future research could effectively address the issue of the possible impact of natural radiation on the biota inhabiting this HBRA. PMID:23185629

  3. Environmental dose rate distribution along the Romanian Black Sea shore

    NASA Astrophysics Data System (ADS)

    Duliu, Octavian G.; Margineanu, Romul M.; Blebea-Apostu, Ana-Maria; Gomoiu, Claudia; Bercea, Sorin

    2013-04-01

    The radiometric investigation of the natural radioactivity dose rate distribution along the most important Romanian Black Sea tourist resorts showed values between 34 and 54 nSv/h, lower than the 59 nSv/h, the average background reported for the entire Romanian territory. At the same time we have noticed that the experimental dose rates monotonously increase northward, reaching a maximum in the vicinity of Vadu and Corbu beaches, both on the southern part of the Chituc sandbank. Concurrent gamma ray spectrometric measurements, performed at the Slanic-Prahova Low-Background Radiation Laboratory for sand samples collected from the same location, have shown that the natural radionuclides have a major contribution to background radiation while anthropogenic Cs-137 plays, 26 years after Chernobyl catastrophe, a negligible role. The experimental values of activity concentrations of all radionuclides present in sand samples were used to calculate the corresponding values of dose rates to which, by adding the contribution of cosmic rays, we have obtained values coincident, within experimental uncertainties, with the experimental ones. At the same time, on Chituc sandbank, a transverse profile of dose rate distribution revealed the presence of some local maxima, two to thee times higher then the average ones. Subsequent gamma ray spectrometry showed an increased content of natural radionuclides, most probably due to a local accumulation of heavy minerals, a common occurrence in the vicinity of river deltas, in our case the Danube Delta. In such a way, the monitoring of local dose rate distribution could be very useful not only in attesting the environmental quality of various resorts and beaches, but also, in signaling the presence of heavy minerals, with beneficent economic consequences.

  4. Parental, Residential, and Self-Belief Factors Influencing Academic Persistence Decisions of College Freshmen

    ERIC Educational Resources Information Center

    Walsh, Kelsey J.; Robinson Kurpius, Sharon E.

    2016-01-01

    Based on Tinto's model of academic persistence, this study explored background and personal factors that theoretically impact the academic persistence decisions of college freshmen. The factors studied were (a) parental educational attainment, (b) parental valuing of education, (c) high school grade point average, (d) residential status (on- vs.…

  5. New Cadets and Other College Freshmen: Class of 1985.

    DTIC Science & Technology

    1982-04-01

    secondary school and socioeconomic backgrounds, values, interests, and activity patterns, and are based on the American Council on Education’s yearly...Year Graduated from High School ................................ 6 9. Distance from Home to College .................................. 6 10. Parents...Activities During Past Year .................................... 14 II. SECONDARY SCHOOL PERFORMANCE 19. Average Grade in Secondary School

  6. Source and Assessment of Metal Pollution at Khetri Copper Mine Tailings and Neighboring Soils, Rajasthan, India.

    PubMed

    Punia, Anita; Siddaiah, N Siva; Singh, Saurabh K

    2017-11-01

    We present here the results of the study on metal pollution by identifying source, abundance and distribution in soil and tailings of Khetri copper complex (KCC) mines, Rajasthan India. The region is highly contaminated by copper (Cu) with higher values in the soil near overburden material (1224 mg/kg) and tailings (111 mg/kg). The average Cu (231 mg/kg) concentration of soil is ~9, 5 and 32 times higher than upper crust, world average shale (WAS) and local background soil (LS), respectively. However this reaches to ~82, 46 and 280 times higher in case of tailing when compared. The correlation and principal component analysis for soil reveals that the source of Cu, Zn, Co, Ni, Mn and Fe is mining and Pb and Cd could be result of weathering of parent rocks and other anthropogenic activities. The source for Cr in soil is both mining activities and weathering of parent rocks. The values of index of geo-accumulation (I geo ) and pollution load index for soil using LS as background are higher compared to values calculated using WAS. The metal rich sulphide bearing overburden material as well as tailings present in the open environment at KCC mines region warrants a proper management to minimize their impact on the environment.

  7. A method of reducing background fluctuation in tunable diode laser absorption spectroscopy

    NASA Astrophysics Data System (ADS)

    Yang, Rendi; Dong, Xiaozhou; Bi, Yunfeng; Lv, Tieliang

    2018-03-01

    Optical interference fringe is the main factor that leads to background fluctuation in gas concentration detection based on tunable diode laser absorption spectroscopy. The interference fringes are generated by multiple reflections or scatterings upon optical surfaces in optical path and make the background signal present an approximated sinusoidal oscillation. To reduce the fluctuation of the background, a method that combines dual tone modulation (DTM) with vibration reflector (VR) is proposed in this paper. The combination of DTM and VR can make the unwanted periodic interference fringes to be averaged out and the effectiveness of the method in reducing background fluctuation has been verified by simulation and real experiments in this paper. In the detection system based on the proposed method, the standard deviation (STD) value of the background signal is decreased to 0.0924 parts per million (ppm), which is reduced by a factor of 16 compared with that of wavelength modulation spectroscopy. The STD value of 0.0924 ppm corresponds to the absorption of 4 . 328 × 10-6Hz - 1 / 2 (with effective optical path length of 4 m and integral time of 0.1 s). Moreover, the proposed method presents a better stable performance in reducing background fluctuation in long time experiments.

  8. The reliability of the Bad Sobernheim Stress Questionnaire (BSSQbrace) in adolescents with scoliosis during brace treatment

    PubMed Central

    Botens-Helmus, Christine; Klein, Rolf; Stephan, Carola

    2006-01-01

    Background A new instrument to assess stress scoliosis patients have whilst wearing their brace has been developed. Aim of this study was to test the reliability of this new instrument. Methods Eight questions are provided focussing on this topic only, including two questions to test the credibility. A max. score of 24 can be achieved (from 0 for most stress to 24 for least stress). We have proposed a subdivision of the score values as follows: 0–8 (strong stress), 9–16 (medium stress) and 17–24 (little stress). 85 patients were invited to take part in this study and to complete the BSSQbrace questionnaire twice, once at the first presentation and a second after a further three days. 62 patients with an average age of 14,5 years and an average Cobb angle of 40° returned their fully completed questionnaires. Results The average stress value was 12,5/24 at the first measurement and 12,4/24 at the second measurement. Ceiling value was 23; floor value 2. The average stress value was 12,5 / 24 at the first measurement and 12,4 / 24 at the second measurement (from 0 for most stress to 24 for least stress). Ceiling value was 23; floor value 2. There was a correlation of 0,88 (Intraclass Correlation Coefficient) between the values of the two measurements. Cronbach alpha was 0, 97. Conclusion The BSSQbrace questionnaire is reliable with good internal consistency and reproducibility. It can be used to measure the coping strategies a patient uses and the impairment a patient feels to have, whilst wearing a brace. PMID:17176483

  9. Radioactivity in the groundwater of a high background radiation area.

    PubMed

    Shabana, E I; Kinsara, A A

    2014-11-01

    Natural radioactivity was measured in groundwater samples collected from 37 wells scattered in an inhabited area of high natural background radiation, in a purpose of radiation protection. The study area is adjacent to Aja heights of granitic composition in Hail province, Saudi Arabia. Initial screening for gross α and gross β activities showed levels exceeded the national regulation limits set out for gross α and gross β activities in drinking water. The gross α activity ranged from 0.17 to 5.41 Bq L(-)(1) with an average value of 2.15 Bq L(-)(1), whereas gross β activity ranged from 0.48 to 5.16 Bq L(-)(1), with an average value of 2.60 Bq L(-)(1). The detail analyses indicated that the groundwater of this province is contaminated with uranium and radium ((226)Ra and (228)Ra). The average activity concentrations of (238)U, (234)U, (226)Ra and (228)Ra were 0.40, 0.77, 0.29 and 0.46 Bq L(-)(1), respectively. The higher uranium content was found in the samples of granitic aquifers, whereas the higher radium content was found in the samples of sandstone aquifers. Based on the obtained results, mechanism of leaching of the predominant radionuclides has been discussed in detail. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Serum concentrations of polychlorinated dibenzo-p-dioxins among ceramicists.

    PubMed

    Demond, Avery; Jiang, Xiaohui; Broadwater, Kendra; Meeker, John; Luksemburg, William; Maier, Martha; Garabrant, David; Franzblau, Alfred

    2015-01-01

    Polychlorinated dibenzo-p-dioxins (PCDDs) occur naturally in ball clay at elevated concentrations. Thus, persons who habitually work with clay may be at risk for exposure to PCDDs. An earlier case report provided some evidence of elevated PCDD levels in serum for long-term hobby ceramicists; however, no previous study has measured serum dioxin concentrations among ceramicists. This study measured PCDD serum levels for 27 individuals involved in ceramics making. The average residual, defined as the average of the [log measured serum lipid concentration – log background serum lipid concentration], was calculated and then tested to determine whether it was significantly different from zero. The p-values for the average residuals indicated that the serum lipid concentrations for several PCDD congeners were elevated relative to background. The number of significant residuals increased dramatically if the background concentrations were adjusted to account for the fact that they were not contemporaneous with the measurements for the ceramicists. The ratio of the 1,2,3,6,7,8-HxCDD concentration to the 1,2,3,7,8,9-HxCDD concentration was greater than 1.0, unlike in ball clay, suggesting that although long-term working with ball clay elevates the PCDD levels in serum somewhat, it is not the predominant source of the PCDD body burden for ceramicists.

  11. Assessment of natural radioactivity levels in soil samples from some areas in Assiut, Egypt.

    PubMed

    El-Gamal, Hany; Farid, M El-Azab; Abdel Mageed, A I; Hasabelnaby, M; Hassanien, Hassanien M

    2013-12-01

    The natural radioactivity of soil samples from Assiut city, Egypt, was studied. The activity concentrations of 28 samples were measured with a NaI(Tl) detector. The radioactivity concentrations of (226)Ra, (232)Th, and (40)K showed large variations, so the results were classified into two groups (A and B) to facilitate the interpretation of the results. Group A represents samples collected from different locations in Assiut and characterized by low activity concentrations with average values of 46.15 ± 9.69, 30.57 ± 4.90, and 553.14 ± 23.19 for (226)Ra, (232)Th, and (40)K, respectively. Group B represents samples mainly collected from the area around Assiut Thermal Power Plant and characterized by very high activity concentrations with average values of 3,803 ± 145, 1,782 ± 98, and 1,377 ± 78 for (226)Ra, (232)Th, and (40)K, respectively. In order to evaluate the radiological hazard of the natural radioactivity, the radium equivalent activity (Raeq), the absorbed dose rate (D), the annual effective dose rate (E), the external hazard index (H ex), and the annual gonadal dose equivalent (AGDE) have been calculated and compared with the internationally approved values. For group A, the calculated averages of these parameters are in good agreement with the international recommended values except for the absorbed dose rate and the AGDE values which are slightly higher than the international recommended values. However, for group B, all obtained averages of these parameters are much higher by several orders of magnitude than the international recommended values. The present work provides a background of radioactivity concentrations in the soil of Assiut.

  12. [Pollution Assessment and Spatial Distribution Characteristics of Heavy Metals in Soils of Coal Mining Area in Longkou City].

    PubMed

    Liu, Shuo; Wu, Quan-yuan; Cao, Xue-jiang; Wang, Ji-ning; Zhang, Long-long; Cai, Dong-quan; Zhou, Li-yuan; Liu, Na

    2016-01-15

    The present paper takes the coal mining area of Longkou City as the research area. Thirty-six topsoil (0-20 cm) samples were collected and the contents of 5 kinds of heavy metals were determined, including Cd, As, Ni, Ph, Cr. Geo-statistics analysis was used to analyze the spatial distribution of heavy metals. Principal component analysis (PCA) was used to explore the pollution sources of heavy metals and the degree of heavy metals pollution was evaluated by weighted average comprehensive pollution evaluation method. The results showed that enrichment phenomenon was significant for the 5 kinds of heavy metals. Taking secondary standard of National Environment Quality Standard for Soil as the background value, their exceed standard rates were 72.22%, 100%, 100%, 91.67%, 100%, respectively. Average contents of heavy metals in the soil samples were all over the national standard level two and were 1.53, 11.86, 2.40, 1.31, 4.09 times of the background value. In addition, the average contents were much higher than the background value of the topsoil in the eastern part of Shandong Province and were 9.85, 39.98, 8.85, 4.29, 12.71 times of the background value. According to the semivariogram model, we obtained the nugget-effects of 5 kinds of heavy metals and their values were in the order of As (0.644) > Cd (0.627) > Cr (0.538) > Ni (0.411) > Pb (0.294), all belonging to moderate spatial correlation. On the whole, the central part of the Sangyuan Coal Mine and its surrounding areas were the most seriously polluted, while the pollution of heavy metals in the east and west of the study area was relatively light. Principal component analysis suggested that the enrichment of Cd, As, Ni, Cr was due to irrigation of wastewater, the discharge of industry and enterprise, and the industrial activity. Automobile exhaust and coal combustion were the main pollution sources of Pb. The single-factor assessment of heavy metals pollution showed that the degree of different heavy metals pollution was in the order of As > Cr > Ni > Cd > Pb. Simultaneously, comprehensive pollution evaluation showed that the degree of heavy metals pollution in the study area was very serious, with comprehensive pollution index ranging from 2.17 to 4.66, among which, the numbers of moderate and heavy pollution samples were 10 and 26, respectively. Areas with heavy pollution were mainly distributed in the Sangyuan Coal Mine, Beizao Coal Mine, Liuhai Coal Mine; and the areas with moderate pollution covered Wali Coal Mine, Liangjia Coal Mine, and other regions. The results of this paper will provide data reference and theoretical support for the study of ecological risk assessment in the study area.

  13. Heat flow and hydrocarbon generation in the Transylvanian basin, Romania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cranganu, C.; Deming, D.

    1996-10-01

    The Transylvanian basin in central Romania is a Neogene depression superimposed on the Cretaceous nappe system of the Carpathian Mountains. The basin contains the main gas reserves of Romania, and is one of the most important gas-producing areas of continental Europe; since 1902, gas has been produced from more than 60 fields. Surface heat flow in the Transylvanian basin as estimated in other studies ranges from 26 to 58 mW/m{sup 2}, with a mean value of 38 mW/m{sup 2}, relatively low compared to surrounding areas. The effect of sedimentation on heat flow and temperature in the Transylvanian basin was estimatedmore » with a numerical model that solved the heat equation in one dimension. Because both sediment thickness and heat flow vary widely throughout the Transylvanian basin, a wide range of model variables were used to bracket the range of possibilities. Three different burial histories were considered (thin, average, and thick), along with three different values of background heat flow (low, average, and high). Altogether, nine different model permutations were studied. Modeling results show that average heat flow in the Transylvanian basin was depressed approximately 16% during rapid Miocene sedimentation, whereas present-day heat flow remains depressed, on average, about 17% below equilibrium values. We estimated source rock maturation and the timing of hydrocarbon generation by applying Lopatin`s method. Potential source rocks in the Transylvanian basin are Oligocene-Miocene, Cretaceous, and Jurassic black shales. Results show that potential source rocks entered the oil window no earlier than approximately 13 Ma, at depths of between 4200 and 8800 m. Most simulations encompassing a realistic range of sediment thicknesses and background heat flows show that potential source rocks presently are in the oil window; however, no oil has ever been discovered or produced in the Transylvanian basin.« less

  14. Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system

    DOEpatents

    Kieper, Douglas Arthur [Seattle, WA; Majewski, Stanislaw [Morgantown, WV; Welch, Benjamin L [Hampton, VA

    2012-07-03

    An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.

  15. Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system

    DOEpatents

    Kieper, Douglas Arthur [Newport News, VA; Majewski, Stanislaw [Yorktown, VA; Welch, Benjamin L [Hampton, VA

    2008-10-28

    An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.

  16. Semiclassical black holes expose forbidden charges and censor divergent densities

    NASA Astrophysics Data System (ADS)

    Brustein, Ram; Medved, A. J. M.

    2013-09-01

    Classically, the horizon of a Schwarzschild black hole (BH) is a rigid surface of infinite redshift; whereas the uncertainty principle dictates that the semiclassical (would-be) horizon cannot be fixed in space nor can it exhibit any divergences. We propose that this distinction underlies the BH information-loss paradox, the apparent absence of BH hair, the so-called trans-Planckian problem and the recent "firewall" controversy. We argue that the correct prescription is to first integrate out the fluctuations of the background geometry and only then evaluate matter observables. The basic idea is illustrated using a system of two strongly coupled harmonic oscillators, with the heavier oscillator representing the background. We then apply our proposal to matter fields near a BH horizon, initially treating the matter fields as classical and the background as semiclassical. In this case, the average value of the associated current does not vanish; so that it is possible, in pr inciple, to measure the global charge of the BH. Then the matter is, in addition to the background, treated quantum mechanically. We show that the average energy density of matter as seen by an asymptotic observer is finite and proportional to the BH entropy, rather than divergent. We discuss the implications of our results for the various controversial issues concerning BH physics.

  17. Binarization algorithm for document image with complex background

    NASA Astrophysics Data System (ADS)

    Miao, Shaojun; Lu, Tongwei; Min, Feng

    2015-12-01

    The most important step in image preprocessing for Optical Character Recognition (OCR) is binarization. Due to the complex background or varying light in the text image, binarization is a very difficult problem. This paper presents the improved binarization algorithm. The algorithm can be divided into several steps. First, the background approximation can be obtained by the polynomial fitting, and the text is sharpened by using bilateral filter. Second, the image contrast compensation is done to reduce the impact of light and improve contrast of the original image. Third, the first derivative of the pixels in the compensated image are calculated to get the average value of the threshold, then the edge detection is obtained. Fourth, the stroke width of the text is estimated through a measuring of distance between edge pixels. The final stroke width is determined by choosing the most frequent distance in the histogram. Fifth, according to the value of the final stroke width, the window size is calculated, then a local threshold estimation approach can begin to binaries the image. Finally, the small noise is removed based on the morphological operators. The experimental result shows that the proposed method can effectively remove the noise caused by complex background and varying light.

  18. Stressed and unstressed Ge:Ga detector arrays for airborne astronomy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stacey, G.J.; Beeman, J.W.; Haller, E.E.

    1992-11-01

    We have constructed and used two dimensional arrays of both unstressed and stressed Ge:GA photoconductive detectors for far-infrared astronomy from the Kuiper Airborne Observatory (KAO). The 25 element (5 x 5) arrays are designed for a new cryogenically cooled spectrometer, the MPE/UCB Far-Infrared Imaging Fabry-Perot Interferometer (FIFI). All of the pixels for the stressed array performed well on the first flights with FIFI; 25% of the detectors in the array are more sensitive than our best single element detector, with background limited noise equivalent powers (NEPs) [approx lt] 3.0 [times] 10[sup [minus]15] W Hz[sup [minus]1/2] at 158 [mu]m and 40more » km s[sup [minus]1] spectral resolution. The average array element performs within [plus minus] 15% of this value. With a bias field of 0.1 V/cm, the average detector response is 20 [plus minus] 6 Amp/Watt at 158 [mu]m. The cutoff wavelength and response also compare well with our single element detectors. The unstressed array delivers significantly better performance than our single element detector due to the lower thermal background in the new spectrometer. The average background limited NEP at 88 [mu]m and 35 km s[sup [minus]1] spectral resolution is approx. 7 [times] 10[sup [minus]15] W Hz[sup [minus]1/2]. 18 refs., 10 figs., 2 tabs.« less

  19. Precision half-life measurement of 11C: The most precise mirror transition F t value

    NASA Astrophysics Data System (ADS)

    Valverde, A. A.; Brodeur, M.; Ahn, T.; Allen, J.; Bardayan, D. W.; Becchetti, F. D.; Blankstein, D.; Brown, G.; Burdette, D. P.; Frentz, B.; Gilardy, G.; Hall, M. R.; King, S.; Kolata, J. J.; Long, J.; Macon, K. T.; Nelson, A.; O'Malley, P. D.; Skulski, M.; Strauss, S. Y.; Vande Kolk, B.

    2018-03-01

    Background: The precise determination of the F t value in T =1 /2 mixed mirror decays is an important avenue for testing the standard model of the electroweak interaction through the determination of Vu d in nuclear β decays. 11C is an interesting case, as its low mass and small QE C value make it particularly sensitive to violations of the conserved vector current hypothesis. The present dominant source of uncertainty in the 11CF t value is the half-life. Purpose: A high-precision measurement of the 11C half-life was performed, and a new world average half-life was calculated. Method: 11C was created by transfer reactions and separated using the TwinSol facility at the Nuclear Science Laboratory at the University of Notre Dame. It was then implanted into a tantalum foil, and β counting was used to determine the half-life. Results: The new half-life, t1 /2=1220.27 (26 ) s, is consistent with the previous values but significantly more precise. A new world average was calculated, t1/2 world=1220.41 (32 ) s, and a new estimate for the Gamow-Teller to Fermi mixing ratio ρ is presented along with standard model correlation parameters. Conclusions: The new 11C world average half-life allows the calculation of a F tmirror value that is now the most precise value for all superallowed mixed mirror transitions. This gives a strong impetus for an experimental determination of ρ , to allow for the determination of Vu d from this decay.

  20. Assessment of indoor radon, thoron concentrations, and their relationship with seasonal variation and geology of Udhampur district, Jammu & Kashmir, India.

    PubMed

    Kumar, Ajay; Sharma, Sumit; Mehra, Rohit; Narang, Saurabh; Mishra, Rosaline

    2017-07-01

    Background The inhalation doses resulting from the exposure to radon, thoron, and their progeny are important quantities in estimating the radiation risk for epidemiological studies as the average global annual effective dose due to radon and its progeny is 1.3 mSv as compared to that of 2.4 mSv due to all other natural sources of ionizing radiation. Objectives The annual inhalation dose has been assessed with an aim of investigating the health risk to the inhabitants of the studied region. Methods Time integrated deposition based 222 Rn/ 220 Rn sensors have been used to measure concentrations in 146 dwellings of Udhampur district, Jammu and Kashmir. An active smart RnDuo monitor has also been used for comparison purposes. Results The range of indoor radon/thoron concentrations is found to vary from 11 to 58 Bqm -3 with an average value of 29 ± 9 Bqm -3 and from 25 to 185 Bqm -3 with an average value of 83 ± 32 Bqm -3 , respectively. About 10.7% dwellings have higher values than world average of 40 Bqm -3 prescribed by UNSCEAR. The relationship of indoor radon and thoron levels with different seasons, ventilation conditions, and different geological formations have been discussed. Conclusions The observed values of concentrations and average annual effective dose due to radon, thoron, and its progeny in the study area have been found to be below the recommended level of ICRP. The observed concentrations of 222 Rn and 220 Rn measured with active and passive techniques are found to be in good agreement.

  1. Human response to high-background radiation environments on Earth and in space

    NASA Astrophysics Data System (ADS)

    Durante, M.; Manti, L.

    2008-09-01

    The main long-term objective of the space exploration program is the colonization of the planets of the Solar System. The high cosmic radiation equivalent dose rate represents an inescapable problem for the safe establishment of permanent human settlements on these planets. The unshielded equivalent dose rate on Mars ranges between 100 and 200 mSv/year, depending on the Solar cycle and altitude, and can reach values as high as 360 mSv/year on the Moon. The average annual effective dose on Earth is about 3 mSv, nearly 85% of which comes from natural background radiation, reduced to less than 1 mSv if man-made sources and the internal exposure to Rn daughters are excluded. However, some areas on Earth display anomalously high levels of background radiation, as is the case with thorium-rich monazite bearing sand deposits where values 200 400 times higher than the world average can be found. About 2% of the world’s population live above 3 km and receive a disproportionate 10% of the annual effective collective dose due to cosmic radiation, with a net contribution to effective dose by the neutron component which is 3 4 fold that at sea level. Thus far, epidemiological studies have failed to show any adverse health effects in the populations living in these terrestrial high-background radiation areas (HBRA), which provide an unique opportunity to study the health implications of an environment that, as closely as possibly achievable on Earth, resembles the chronic exposure of future space colonists to higher-than-normal levels of ionizing radiation. Chromosomal aberrations in the peripheral blood lymphocytes from the HBRA residents have been measured in several studies because chromosomal damage represents an early biomarker of cancer risk. Similar cytogenetic studies have been recently performed in a cohort of astronauts involved in single or repeated space flights over many years. The cytogenetic findings in populations exposed to high dose-rate background radiation on Earth or in space will be discussed.

  2. [Distribution of Urban Soil Heavy Metal and Pollution Evaluation in Different Functional Zones of Yinchuan City].

    PubMed

    Wang, You-qi; Bai, Yi-ru; Wang, Jian-yu

    2016-02-15

    Surface soil samples (0-20 cm) from eight different functional areas in Yinchuan city were collected. There were 10 samples respectively in each functional area. The urban soil heavy metals (Zn, Cd, Pb, Mn, Cu and Cr) pollution characteristics and sources in eight different functional areas were evaluated by mathematical statistics and geostatistical analysis method. Meanwhile, the spatial distributions of heavy metals based on the geography information system (GIS) were plotted. The average values of total Zn, Cd, Pb, Mn, Cu and Cr were 74.87, 0.15, 29.02, 553.55, 40.37 and 80.79 mg x kg(-1), respectively. The results showed that the average value of soil heavy metals was higher than the soil background value of Ningxia, which indicated accumulation of the heavy metals in urban soil. The single factor pollution index of soil heavy metals was in the sequence of Cu > Pb > Zn > Cr > Cd > Mn. The average values of total Zn, Cd, Pb and Cr were higher in north east, south west and central city, while the average values of Mn and Cu were higher in north east and central city. There was moderate pollution in road and industrial area of Yinchuan, while the other functional areas showed slight pollution according to Nemoro synthesis index. The pollution degree of different functional areas was as follows: road > industrial area > business district > medical treatment area > residential area > public park > development zone > science and education area. The results indicated that the soil heavy metal pollution condition in Yinchuan City has been affected by human activities with the development of economy.

  3. Observations of Atmospheric Δ14CO2 at the Global and Regional Background Sites in China: Implication for Fossil Fuel CO2 Inputs.

    PubMed

    Niu, Zhenchuan; Zhou, Weijian; Cheng, Peng; Wu, Shugang; Lu, Xuefeng; Xiong, Xiaohu; Du, Hua; Fu, Yunchong

    2016-11-15

    Six months to more than one year of atmospheric Δ 14 CO 2 were measured in 2014-2015 at one global background site in Waliguan (WLG) and four regional background sites at Shangdianzi (SDZ), Lin'an (LAN), Longfengshan (LFS) and Luhuitou (LHT), China. The objectives of the study are to document the Δ 14 CO 2 levels at each site and to trace the variations in fossil fuel CO 2 (CO 2ff ) inputs at regional background sites. Δ 14 CO 2 at WLG varied from 7.1 ± 2.9‰ to 32.0 ± 3.2‰ (average 17.1 ± 6.8‰) in 2015, with high values generally in autumn/summer and low values in winter/spring. During the same period, Δ 14 CO 2 values at the regional background sites were found to be significantly (p < 0.05) lower than those at WLG, indicating different levels of CO 2ff inputs at those sites. CO 2ff concentrations at LAN (12.7 ± 9.6 ppm) and SDZ (11.5 ± 8.2 ppm) were significantly (p < 0.05) higher than those at LHT (4.6 ± 4.3 ppm) in 2015. There were no significant (p > 0.05) seasonal differences in CO 2ff concentrations for the regional sites. Regional sources contributed in part to the CO 2ff inputs at LAN and SDZ, while local sources dominated the trend observed at LHT. These data provide a preliminary understanding of atmospheric Δ 14 CO 2 and CO 2ff inputs for a range of Chinese background sites.

  4. Assessment of toxic metal contamination using a regional lithogenic geochemical background, Pampean area river basin, Argentina.

    PubMed

    Castro, Liliana Norma; Rendina, Alicia Elena; Orgeira, Maria Julia

    2018-06-15

    Contamination assessment in riverbed sediments depends on the accurate determination of the background values. The aim of this study is to assess the degree of contamination and to evaluate the most adequate background for the determination of anthropogenic contamination in Cd, Cr, Cu, Ni, Pb and Zn in bed sediments of the Pampean area river basin (Matanza-Riachuelo River and tributary streams), Argentina. The geo-accumulation index (Igeo) values were calculated using selected lithogenic backgrounds (loess, loessoid sediments and paleosoils), the metal concentrations in the residual fraction (F4) in riverbed sediments and a global average shale often applied in the estimation of toxic metal Igeo. The IgeoF4, IgeoLZB and most of the others Igeos, indicated that in land areas used mainly for agriculture and cattle grazing, the superficial sediments were uncontaminated with Cd, Cr, Cu and Zn, and slightly contaminated with Ni and Pb. Conversely, in those areas dedicated to urban and industrial use, the metal contamination was greater. Overall, the relatively significant anthropogenic contamination of Cr > Pb ≥ Cu > Zn > Ni > Cd in the Riachuelo River area was associated with metallurgic activities, tanning and industrial waste. The comparative analysis of different values suggested that Buenos Aires' "pristine" loess could be recommended to evaluate the Igeo index of riverbed sediments in the Pampean area. To enhance the use of the selected background, the normalized enrichment factor using Al. In this study case, the Igeo and the EF using LZB background display the same trend, showing the greatest degree of contamination, as would be expected, in Riachuelo samples (RIA 1 and RIA 2) located in the urban/industrial area. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. A contrast-sensitive channelized-Hotelling observer to predict human performance in a detection task using lumpy backgrounds and Gaussian signals

    NASA Astrophysics Data System (ADS)

    Park, Subok; Badano, Aldo; Gallas, Brandon D.; Myers, Kyle J.

    2007-03-01

    Previously, a non-prewhitening matched filter (NPWMF) incorporating a model for the contrast sensitivity of the human visual system was introduced for modeling human performance in detection tasks with different viewing angles and white-noise backgrounds by Badano et al. But NPWMF observers do not perform well detection tasks involving complex backgrounds since they do not account for random backgrounds. A channelized-Hotelling observer (CHO) using difference-of-Gaussians (DOG) channels has been shown to track human performance well in detection tasks using lumpy backgrounds. In this work, a CHO with DOG channels, incorporating the model of the human contrast sensitivity, was developed similarly. We call this new observer a contrast-sensitive CHO (CS-CHO). The Barten model was the basis of our human contrast sensitivity model. A scalar was multiplied to the Barten model and varied to control the thresholding effect of the contrast sensitivity on luminance-valued images and hence the performance-prediction ability of the CS-CHO. The performance of the CS-CHO was compared to the average human performance from the psychophysical study by Park et al., where the task was to detect a known Gaussian signal in non-Gaussian distributed lumpy backgrounds. Six different signal-intensity values were used in this study. We chose the free parameter of our model to match the mean human performance in the detection experiment at the strongest signal intensity. Then we compared the model to the human at five different signal-intensity values in order to see if the performance of the CS-CHO matched human performance. Our results indicate that the CS-CHO with the chosen scalar for the contrast sensitivity predicts human performance closely as a function of signal intensity.

  6. Plant/soil concentration ratios of SSWRa for contrasting sites around an active U mine-mill

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ibrahim, S.A.; Whicker, F.W.

    Concentrations of 226Ra were determined in native vegetation and underlying substrate (soil and tailings) at various sites around a conventional open-pit, acid leach U production operation in Wyoming. Plant/soil concentration ratios (CRs) for 226Ra were estimated for various sites, including weathered tailings; a tailings impoundment shoreline; downwind from exposed tailings; a mine overburden reclamation area; and several background locations. Radium-226 concentrations for vegetation and substrate and CR values from the perturbed sites were elevated above background. The highest vegetation concentration (1.3 Bq g-1) was found in a grass which had invaded exposed, weathered tailings. Levels of 226Ra in soil andmore » vegetation and CR values decreased with distance from the tailings impoundment edge. CR values varied significantly among sites, but few differences were found between plant species groups. The observed CR values ranged from 0.07 at the background and reclamation areas to 0.4 downwind from the tailings area. Average CR values for plants growing on exposed tailings and within one meter from the impoundment edge were 0.15 and 0.3, respectively. CR values of 226Ra for plants on tailings substrates were comparatively low in contrast to other radionuclides in the U chain. We speculate that in the case of sulfuric acid leached tailings-derived material, 226Ra is sequestered as sulfate, which is highly insoluble relative to the sulfates of the other elements (e.g., U and Th) resulting in reduced availability for plant uptake.« less

  7. Study of natural radioactivity in Mansehra granite, Pakistan: environmental concerns.

    PubMed

    Qureshi, Aziz Ahmed; Jadoon, Ishtiaq Ahmed Khan; Wajid, Ali Abbas; Attique, Ahsan; Masood, Adil; Anees, Muhammad; Manzoor, Shahid; Waheed, Abdul; Tubassam, Aneela

    2014-03-01

    A part of Mansehra Granite was selected for the assessment of radiological hazards. The average activity concentrations of (226)Ra, (232)Th and (40)K were found to be 27.32, 50.07 and 953.10 Bq kg(-1), respectively. These values are in the median range when compared with the granites around the world. Radiological hazard indices and annual effective doses were estimated. All of these indices were found to be within the criterion limits except outdoor external dose (82.38 nGy h(-1)) and indoor external dose (156.04 nGy h(-1)), which are higher than the world's average background levels of 51 and 55 nGy h(-1), respectively. These values correspond to an average annual effective dose of 0.867 mSv y(-1), which is less than the criterion limit of 1 mSv y(-1) (ICRP-103). Some localities in the Mansehra city have annual effective dose higher than the limit of 1 mSv y(-1). Overall, the Mansehra Granite does not pose any significant radiological health hazard in the outdoor or indoor.

  8. Inhalation Dose and Source Term Studies in a Tribal Area of Wayanad, Kerala, India

    PubMed Central

    Damodaran, Ravikumar C.; Kumar, Visnuprasad Ashok; Panakal John, Jojo; Bangaru, Danalakshmi; Natarajan, Chitra; Sathiamurthy, Bala Sundar; Mundiyanikal Thomas, Jose; Mishra, Rosaline

    2017-01-01

    Among radiation exposure pathways to human beings, inhalation dose is the most prominent one. Radon, thoron, and their progeny contribute more than 50 per cent to the annual effective dose due to natural radioactivity. South west coast of India is classified as a High Natural Background Radioactivity Area and large scale data on natural radioactivity and dosimetry are available from these coastal regions including the Neendakara-Chavara belt in the south of Kerala. However, similar studies and reports from the northern part of Kerala are scarce. The present study involves the data collection and analysis of radon, thoron, and progeny concentration in the Wayanad district of Kerala. The radon concentration was found to be within a range of 12–378 Bq/m3. The thoron concentration varied from 15 to 621 Bq/m3. Progeny concentration of radon and thoron and the diurnal variation of radon were also studied. In order to assess source term, wall and floor exhalation studies have been done for the houses showing elevated concentration of radon and thoron. The average values of radon, thoron, and their progeny are found to be above the Indian average as well as the average values reported from the High Natural Background Radioactivity Areas of Kerala. Exhalation studies of the soil samples collected from the vicinity of the houses show that radon mass exhalation rate varied from below detectable limit (BDL) to a maximum of 80 mBq/kg/h. The thoron surface exhalation rate ranged from BDL to 17470 Bq/m2/h. PMID:28611847

  9. Pollution distribution and health risk assessment of heavy metals in indoor dust in Anhui rural, China.

    PubMed

    Lin, Yuesheng; Fang, Fengman; Wang, Fei; Xu, Minglu

    2015-09-01

    Zn, Pb, Cu, Cr, V, Ni, Co, and As concentrations of indoor dust in Anhui rural were determined by inductively coupled plasma-optical emission spectroscopy (ICP-OES). The degrees of metal pollution in indoor dust ranked as follows: Zn > Pb > Cr > Cu > V > Ni > Co > As, on average. The arithmetic means of Zn, Pb, Cu, Cr, V, Ni, Co, and As were 427.17, 348.73, 107.05, 113.68, 52.64, 38.93, 10.29, and 4.46 mg/kg, respectively. These were higher than background values of Anhui soil for Zn, Pb, Cu, Cr, and Ni, especially for Pb with the mean value of 13.21 times the background value. Heavy metal concentrations of indoor dust were different from different rural areas. House type (bungalows or storied house), sweeping frequency, and external environment around the house (such as the road grade) affected heavy metal concentrations in indoor dust. The results of factor analysis and correlation analysis indicated that Cu, Cr, Ni, Zn, and Co concentrations were mainly due to interior paint, metal objects, and building materials. Pb and As concentrations were due to vehicle emissions. V concentration was mainly of natural source. Average daily doses for the exposure pathway of the studied heavy metals decreased in children in the following order: hand-to-mouth ingestion > dermal contact > inhalation. The non-carcinogenic risks of heavy metals ranked as Pb > V > Cr > Cu > Zn > As > Co > Ni, and the carcinogenic risks of metals decreased in the order of Cr > Co > As > Ni. The non-carcinogenic hazard indexes and carcinogenic risks of metals in indoor dust were both lower than the safe values.

  10. Department of Defense Food Procurement: Background and Status

    DTIC Science & Technology

    2008-08-28

    and guidelines for the acquisition of subsistence items. The solicitation is prepared based on what represents the best value to the federal government...www.natick.army.mil/soldier/media/fact/food/mre.htm]. One MRE provides an average of 1,250 calories composed of 13% protein , 36% fat, and 51...for the military, the military services also consider the special dietary needs of the soldiers (including vegetarian and kosher needs). The Produce

  11. Spectroscopic studies of the parameters of plasma jets during their propagation in the background plasma on the PF-3 facility

    NASA Astrophysics Data System (ADS)

    Dan'ko, S. A.; Ananyev, S. S.; Kalinin, Yu G.; Krauz, V. I.; Myalton, V. V.

    2017-04-01

    This paper presents measurement results of neon and helium plasma parameters in axial jets generated in plasma focus discharge. They were obtained in the course of experiments on laboratory modeling of astrophysical jets performed at the PF-3 facility. The plasma concentration was determined according to Stark broadening of spectral lines; the ionization temperature was determined by the average ion charge. The values of the concentration and temperature of jet plasma and background plasma at two distances from the pinch are also presented. In addition, an estimation was made of the heat content losses of the neon and helium jets during their movement through the surrounding medium.

  12. Comparing Background and Recent Erosion Rates in Degraded Areas of Southeastern Brazil

    NASA Astrophysics Data System (ADS)

    Fernandes, N.; Bierman, P. R.; Sosa-Gonzalez, V.; Rood, D. H.; Fontes, R. L.; Santos, A. C.; Godoy, J. M.; Bhering, S.

    2014-12-01

    Soil erosion is a major problem in northwestern Rio de Janeiro State where, during the last three centuries, major land-use changes took place, associated with the replacement of the original rainforest by agriculture and grazing. The combination of steep hillslopes, erodible soils, sparse vegetation, natural and human-induced fires, as well as downslope ploughing, led to an increase in surface runoff and surface erosion on soil-mantled hillslopes; together, these actions and responses caused a decline in soil productivity. In order to estimate changes in erosion rates over time, we compared erosion rates measured at different spatial and temporal scales, both background (natural) and short-term (human-induced during last few decades). Background long-term erosion rates were measured using in-situ produced cosmogenic 10Be in the sand fraction quartz of active river channel sediment in four basins in the northwestern portion of Rio de Janeiro State. In these basins, average annual precipitation varies from 1,200 to 1,300 mm, while drainage areas vary from 15 to 7,200 km2. Short-term erosion rates were measured in one of these basins from fallout 210Pb in soil samples collected along a hillslope transect located in an abandoned agriculture field. In this transect, 190 undisturbed soil samples (three replicates) were collected from the surface to 0.50 m depth (5 cm vertical intervals) in six soil pits. 10Be average background, basin-wide, erosion rates in the area are ~ 13 m/My; over the last decades, time-integrated (210Pb) average hillslope erosion rates are around 1450 m/Myr, with maximum values at the steepest portion of convex hillslopes of about 2000 m/Myr. These results suggest that recent hillslope erosion rates are about 2 orders of magnitude above background rates of sediment generation integrated over many millennia. This unsustainable rate of soil loss has severely decreased soil productivity eventually leading to the abandonment of farming activities in areas where soil loss is severe.

  13. Evaluation of Background Exposures of Americans to Dioxin-Like Compounds in the 1990's and the 2000's

    USDA-ARS?s Scientific Manuscript database

    The US Environmental Protection Agency’s 2004 Dioxin Reassessment included a characterization of background exposures to dioxin-like compounds, including an estimate of an average background intake dose and an average background body burden. These quantities were derived from data generated in the m...

  14. Possible role of organic peroxides in the detection of irradiated food

    NASA Astrophysics Data System (ADS)

    Shengchu, Qi; Jilan, Wu; Yan, Zhu

    1993-07-01

    In order to determine the level of organic peroxides induced by autooxidation, random sampling of pork has been performed with ˜ 300 analytical data. The organic peroxide content in unirradiated pork has been estimated as (5.4±3.0)X10 -5mol.kg -1. The dependence of yield of peroxide in pork, minced meat and braised chicken on absorbed dose has been investigated. For killing trichinae 0.5˜1 kGy is used, the quantity of peroxide in pork will be 2X10 -4mol.kg -1 (or 4X10 -4 mol.kg -1 for 1 kGy), which is 3.7˜7.4 times greater than the background. If 3 kGy is used to eliminate Samonella, the quantity of peroxides in pork will be 1.3X10 -3mol.kg -1., which approaches 24 times greater than the average value of background. When minced meat was irradiated in the presence of air, a chain reaction takes place with G (organic peroxides) value 30.2. Radiation processing dose of braised chicken for shelf-life extension is ˜ 9kGy, organic peroxide content in braised chicken fat is 32.5X10 -4mol.kg -1, which is about 14.7 times greater than average value (2.2X10 -4mol.kg -1) in unirradiated one. Applying peroxide method to qualitatively detect the irradiated food containing fat is satisfactory. Recombining with measuring ESR signal of irradiated bone will cause the method of detection more accurate and perfect.

  15. Influence of background/surrounding area on accuracy of visual color matching.

    PubMed

    Dudea, Diana; Gasparik, Cristina; Botos, Alexandra; Alb, Florin; Irimie, Ada; Paravina, Rade D

    2016-07-01

    Visual shade selection is subjective and influenced by factors that might be operator-dependent or not. The objective was to evaluate influence of observer nonrelated factors (background/surrounding area, and light) and observer-related factors (gender and color competence) on shade-matching quality and to identify the most often mismatched shades in correlation with the background. Ten observers with average or superior color discrimination competence according to ISO TR 28642:2011 were asked to match 48 shade tabs of three VITA Classical shade guides, in a viewing booth under two light sources: D65 and D50. Gray, white, black, red, and light blue background/surrounding area simulated various clinical situations. The results were statistically analyzed using Kruskal-Wallis test and Mann-Whitney U test. Post hoc power analyses and sample size calculations were also conducted. The matching scores ranged between 72.7 % (using blue background) and 85.9 % (using white and black backgrounds). There was a statistically significant difference between matching scores on the five backgrounds (χ (2)(4) = 12.67, p = 0.01). When neutral gray was used as reference, Mann-Whitney U value was statistically significant only for the blue background (U = 107.00, Z = -2.52, p = 0.01). The influence of gender and lighting condition was also assessed, no statistically significance being found, but in both cases, the effect size and the achieved power were small. However, color discrimination competence did influence the results (p < 0.01). Background influenced shade matching results for tabs A3, B3, B4, and D4. Within the limitations of this study, it was concluded that 1. When it comes to the influence of the background/surround area on quality of color matching, no difference among achromatic backgrounds was recorded. Significantly worse results were recorded when the blue background was used. 2. Observers with superior color matching competence performed significantly better than the ones with average competence 3. The most frequently mismatched shade tabs were A3.5, B3, B4, and D4.

  16. [Estimation of average traffic emission factor based on synchronized incremental traffic flow and air pollutant concentration].

    PubMed

    Li, Run-Kui; Zhao, Tong; Li, Zhi-Peng; Ding, Wen-Jun; Cui, Xiao-Yong; Xu, Qun; Song, Xian-Feng

    2014-04-01

    On-road vehicle emissions have become the main source of urban air pollution and attracted broad attentions. Vehicle emission factor is a basic parameter to reflect the status of vehicle emissions, but the measured emission factor is difficult to obtain, and the simulated emission factor is not localized in China. Based on the synchronized increments of traffic flow and concentration of air pollutants in the morning rush hour period, while meteorological condition and background air pollution concentration retain relatively stable, the relationship between the increase of traffic and the increase of air pollution concentration close to a road is established. Infinite line source Gaussian dispersion model was transformed for the inversion of average vehicle emission factors. A case study was conducted on a main road in Beijing. Traffic flow, meteorological data and carbon monoxide (CO) concentration were collected to estimate average vehicle emission factors of CO. The results were compared with simulated emission factors of COPERT4 model. Results showed that the average emission factors estimated by the proposed approach and COPERT4 in August were 2.0 g x km(-1) and 1.2 g x km(-1), respectively, and in December were 5.5 g x km(-1) and 5.2 g x km(-1), respectively. The emission factors from the proposed approach and COPERT4 showed close values and similar seasonal trends. The proposed method for average emission factor estimation eliminates the disturbance of background concentrations and potentially provides real-time access to vehicle fleet emission factors.

  17. Average expansion rate and light propagation in a cosmological Tardis spacetime

    NASA Astrophysics Data System (ADS)

    Lavinto, Mikko; Räsänen, Syksy; Szybka, Sebastian J.

    2013-12-01

    We construct the first exact statistically homogeneous and isotropic cosmological solution in which inhomogeneity has a significant effect on the expansion rate. The universe is modelled as a Swiss Cheese, with dust FRW background and inhomogeneous holes. We show that if the holes are described by the quasispherical Szekeres solution, their average expansion rate is close to the background under certain rather general conditions. We specialise to spherically symmetric holes and violate one of these conditions. As a result, the average expansion rate at late times grows relative to the background, ie backreaction is significant. The holes fit smoothly into the background, but are larger on the inside than a corresponding background domain: we call them Tardis regions. We study light propagation, find the effective equations of state and consider the relation of the spatially averaged expansion rate to the redshift and the angular diameter distance.

  18. 5-year analysis of background surface ozone and carbon dioxide variations during summer seasons at Terra Nova Bay (Antarctica)

    NASA Astrophysics Data System (ADS)

    Cristofanelli, Paolo; Bonasoni, Paolo; Bonafe', Ubaldo; Calzolari, Frencescopiero; Duchi, Rocco; Lanconelli, Christian; Lupi, Angelo; Vitale, Vito; Colombo, Tiziano

    2010-05-01

    Carbon dioxide (CO2) and tropospheric ozone (O3) play important roles in determining the radiative budget of the atmosphere. While CO2 is considered the most important anthropogenic greenhouse gas, O3 is evaluated as the third most powerful greenhouse gas since pre-industrial ages and, by influencing the lifetime of others greenhouse gases, it provides also an indirect impact on climate. Within the framework of the Italian National Programme of Antarctic Researches (PNRA), continuous measurements of CO2, O3 as well as meteorological parameters have been conducted at the clean-air facility of Icaro Camp at the "Mario Zucchelli" Station (74.7 S, 164.1 E, 41 m a.s.l., hereinafter MZS-IC) during five experimental summer campaigns from November 2001 to February 2006. At MZS-IC, average O3 background concentrations ranged from 18.5 +/- 4.6 ppbv (summer 2005 - 2006) to 22.0 +/- 4.3 ppbv (summer 2003 - 2004). For CO2, in good agreement with the global trend observed for the period 2001-2006, background concentrations showed an average growth rate of 2.12 ppmv/year ranging from 369.28 +/- 0.18 ppmv during the summer 2001 - 2002 to 377.76 +/- 0.26 ppmv during the summer 2005 - 2006. On average, over the five summer campaigns, the O3 behaviour showed a decreasing trend with highest values in November and a minimum in January, while a broad December-January minimum characterised CO2, well tracing the typical O3 and CO2 high-latitude seasonal cycles in the Southern Hemisphere.

  19. Spring response to precipitation events using δ(18)O and δ(2)H in the Tanour catchment, NW Jordan.

    PubMed

    Hamdan, Ibraheem; Wiegand, Bettina; Toll, Mathias; Sauter, Martin

    2016-12-01

    The Tanour spring is one of the several karst springs located in the northern part of Jordan. Water samples from the Tanour spring and precipitation were collected in the area of Ajloun in NW Jordan for the analysis of stable oxygen and hydrogen isotopes to evaluate the spring response to precipitation events. Rainwater and snow samples were collected from different elevations during winters of 2013-2014 and 2014-2015. In addition, spring samples were collected between December 2014 and March 2015. δ(18)O values in rainwater vary from -3.26 to -17.34 ‰ (average: -7.84 ± 3.23 ‰), while δ(2)H values range between -4.4 and -110.4 ‰ (average: -35.7 ± 25.0 ‰). Deuterium excess ranges from 17.8 to 34.1 ‰ (average: 27.1 ± 4.0 ‰). The Local Meteoric Water Line for the study area was calculated to be δ(2)H = 7.66*δ(18)O + 24.43 (R(2) = 0.98). Pre-event spring discharge showed variation in δ(18)O (range -6.29 to -7.17 ‰; average -6.58 ± 0.19 ‰) and δ(2)H values (range -28.8 to -32.7 ‰; average: -30.5 ± 1.0 ‰). In contrast, δ(18)O and δ(2)H rapidly changed to more negative values during rainfall and snowmelt events and persisted for several days before returning to background values. Spring water temperature, spring discharge, and turbidity followed the trend in isotopic composition during and after the precipitation events. The rapid change in the isotopic composition, spring discharge, water temperature, and turbidity in response to recharge events is related to fast water travel times and low storage capacity in the conduit system of the karst aquifer. Based on the changes in the isotopic composition of spring water after the precipitation events, the water travel time in the aquifer is in the order of 5-11 days.

  20. The determination of ultraviolet extinction from the optical and near-infrared

    NASA Technical Reports Server (NTRS)

    Cardelli, Jason A.; Clayton, Geoffrey C.; Mathis, John S.

    1988-01-01

    The correlation of optical-near-infrared photometry for a sample of stars with well-determined ultraviolet extinction is examined. A good correlation is found; in particular, it is found that the value of total-to-selective extinction correlates well with the level of linear UV background extinction found from the UV curve parameterization of Fitzpatrick and Massa. An analytic expression is given for an improved estimate for the UV extinction law that can be obtained from optically determined values of R. For R values outside the range R = 3.1 -3.5, use of the analytic expressions given here will result in a more accurate representation of the applicable UV extinction than using the standard techniques of assuming the average curve or 'ironing out' the bump.

  1. Chemical and radiological characterization of fly and bottom ash landfill of the former sulfate pulp factory Plaški and its surroundings.

    PubMed

    Oreščanin, Višnja; Kollar, Robert; Buben, Kresimir; Mikelic, Ivanka Lovrencic; Kollar, Karlo; Kollar, Melkior; Medunic, Gordana

    2012-01-01

    The subject of this study was chemical and radiological characterization of the fly and bottom ash, by-product of the combustion of coal used as an energy source in the former sulfate pulp factory in Plaški. The research involves determination of the concentration of macro, micro and trace elements and activities of the radionuclides in: (i) ash from different positions of the landfill; (ii) soil samples in the zone of the influence of the landfill; (iii) control soil samples and (iv) sediment sample from the river Dretulja. Besides, in situ measurement of an effective dose rate above ash/soil was also determined. In relation with the control soil the average increase of the concentrations of the elements Ca, Cd, Hg, Ni, Se, Sr, Th and U in the samples taken from the fly and bottom ash landfill as well as soil samples within the radius of 300 m from the landfill was 38.3, 6.7, 9.9, 8.5, 9.4, 7.2, 3.6 and 5.7 times, respectively. In these samples, the concentrations of the above mentioned elements were in the following ranges: calcium from 7.94 to 19.7 %; cadmium from 0.33 to 1.66 mg/kg; mercury from 0.18 to 0.49 mg/kg; nickel from 260 to 1500 mg/kg; selenium from 2.7 to 21 mg/kg; strontium from 176 to 542 mg/kg; thorium from 8 to 55 mg/kg and uranium from 5.6 to 19.7 mg/kg. Compared to the world's average soil concentration, uranium and thorium values increased 3.7 and 1.7 times, respectively. The mean value of the total effective dose rate measured in the air at the height of 1 m for all samples of ash and soil under the influence of the landfill was 1.60 mSv/yr. Compared to the Croatian average (0.7015 mSv/yr), the determined mean value for the Plaški landfill is two times higher. However, compared to the local background (0.14 mSv/yr), the mean value of the total effective dose rate measured above the Plaški landfill is 11.4 times higher. In the samples of ash and contaminated soil regardless of the sampling location the activity concentrations of the radionuclides in Bq/kg vary in the following ranges: (226)Ra from 82.10 to 314.90 (mean value 145.99), (232)Th from 32.50 to 223.60 (mean value 76.76) and (238)U from 69.10 to 243.20 (mean value 134.38). Compared to the mean values found in the background soil (226)Ra and (238)U mean activity concentrations increased from 1.6 to 6.4 times and (232)Th from 1.4 to 4.3 times. In order to reduce total effective dose rate to the local "background" values and to prevent redistribution of the radionuclides and heavy metals from the deposited material into the environment fly and bottom ash landfill must be sealed with 10 cm thick layer of the material with low permeability.

  2. Indoor External Radiation Risk in Densely Populated Regions of Southern Nigeria

    NASA Astrophysics Data System (ADS)

    Ife-Adediran, Oluwatobi O.; Uwadiae, Iyobosa B.

    2018-02-01

    It is known that certain types of building materials contain significant concentrations of natural radionuclides; consequently, exposure to indoor background radiation is from the combined radioactivity from the soil as well as building materials; indoor exposures therefore have higher radiation hazard potentials than outdoor exposures in this regard and hence, need to be monitored. In this paper, an evaluation of background ionizing radiation from different buildings in Lagos and Ibadan, Southwestern Nigeria was carried out to determine the exposure rate of the general public to indoor ionizing radiation. 630 in situ measurements from the different buildings were taken using a Geiger Muller counter (model GQ-320 Plus). The indoor dose rates (i.e., 50-120 nGy/h) were within the world average values while the Annual Effective Dose for most of the buildings were above the world average AED for indoor gamma exposure from building materials. The mean AED for Lagos and Ibadan due to indoor exposures were 0.37 and 0.39 mSv/y with Excess Lifetime Cancer Risk of 0.99E-3 and 1.05E-3, respectively.

  3. Indoor External Radiation Risk in Densely Populated Regions of Southern Nigeria

    NASA Astrophysics Data System (ADS)

    Ife-Adediran, Oluwatobi O.; Uwadiae, Iyobosa B.

    2018-05-01

    It is known that certain types of building materials contain significant concentrations of natural radionuclides; consequently, exposure to indoor background radiation is from the combined radioactivity from the soil as well as building materials; indoor exposures therefore have higher radiation hazard potentials than outdoor exposures in this regard and hence, need to be monitored. In this paper, an evaluation of background ionizing radiation from different buildings in Lagos and Ibadan, Southwestern Nigeria was carried out to determine the exposure rate of the general public to indoor ionizing radiation. 630 in situ measurements from the different buildings were taken using a Geiger Muller counter (model GQ-320 Plus). The indoor dose rates (i.e., 50-120 nGy/h) were within the world average values while the Annual Effective Dose for most of the buildings were above the world average AED for indoor gamma exposure from building materials. The mean AED for Lagos and Ibadan due to indoor exposures were 0.37 and 0.39 mSv/y with Excess Lifetime Cancer Risk of 0.99E-3 and 1.05E-3, respectively.

  4. Radiative characteristics of aerosol during extreme fire event over Siberia in summer 2012

    NASA Astrophysics Data System (ADS)

    Zhuravleva, Tatiana B.; Kabanov, Dmitriy M.; Nasrtdinov, Ilmir M.; Russkova, Tatiana V.; Sakerin, Sergey M.; Smirnov, Alexander; Holben, Brent N.

    2017-01-01

    Microphysical and optical properties of aerosol were studied during a mega-fire event in summer 2012 over Siberia using ground-based measurements of spectral solar radiation at the AERONET site in Tomsk and satellite observations. The data were analysed using multi-year (2003-2013) measurements of aerosol characteristics under background conditions and for less intense fires, differing in burning biomass type, stage of fire, remoteness from observation site, etc. (ordinary smoke). In June-August 2012, the average aerosol optical depth (AOD, 500 nm) had been 0.95 ± 0.86, about a factor of 6 larger than background values (0.16 ± 0.08), and a factor of 2.5 larger than in ordinary smoke. The AOD values were extremely high on 24-28 July and reached 3-5. A comparison with satellite observations showed that ground-based measurements in the region of Tomsk not only reflect the local AOD features, but are also characteristic for the territory of Western Siberia as a whole. Single scattering albedo (SSA, 440 nm) in this period ranged from 0.91 to 0.99 with an average of ˜ 0.96 in the entire wavelength range of 440-1020 nm. The increase in absorptance of aerosol particles (SSA(440 nm) = 0.92) and decrease in SSA with wavelength observed in ordinary smoke agree with the data from multi-year observations in analogous situations in the boreal zone of USA and Canada. Volume aerosol size distribution in extreme and ordinary smoke had a bimodal character with significant prevalence of fine-mode particles, but in summer 2012 the mean median radius and the width of the fine-mode distribution somewhat increased. In contrast to data from multi-year observations, in summer 2012 an increase in the volume concentration and median radius of the coarse mode was observed with growing AOD. The calculations of the average radiative effects of smoke and background aerosol are presented. Compared to background conditions and ordinary smoke, under the extreme smoke conditions the cooling effect of aerosol considerably intensifies: direct radiative effects (DRE) at the bottom (BOA) and at the top of the atmosphere (TOA) are -13, -35, and -60 W m-2 and -5, -14, and -35 W m-2 respectively. The maximal values of DRE were observed on 27 July (AOD(500 nm) = 3.5), when DRE(BOA) reached -150 W m-2, while DRE(TOA) and DRE of the atmosphere were -75 W m-2. During the fire event in summer 2012 the direct radiative effect efficiency varied in range: at the BOA it was -80-40 W m-2, at the TOA it was -50-20 W m-2 and in the atmosphere it was -35-20 W m-2.

  5. Noise level in a neonatal intensive care unit in Santa Marta - Colombia.

    PubMed

    Garrido Galindo, Angélica Patricia; Camargo Caicedo, Yiniva; Velez-Pereira, Andres M

    2017-09-30

    The environment of neonatal intensive care units is influenced by numerous sources of noise emission, which contribute to raise the noise levels, and may cause hearing impairment and other physiological and psychological changes on the newborn, as well as problems with care staff. To evaluate the level and sources of noise in the neonatal intensive care unit. Sampled for 20 consecutive days every 60 seconds in A-weighting curves and fast mode with a Type I sound level meter. Recorded the average, maximum and minimum, and the 10th, 50th and 90th percentiles. The values are integrated into hours and work shift, and studied by analysis of variance. The sources were characterized in thirds of octaves. The average level was 64.00 ±3.62 dB(A), with maximum of 76.04 ±5.73 dB(A), minimum of 54.84 ±2.61dB(A), and background noise of 57.95 ±2.83 dB(A). We found four sources with levels between 16.8-63.3 dB(A). Statistical analysis showed significant differences between the hours and work shift, with higher values in the early hours of the day. The values presented exceed the standards suggested by several organizations. The sources identified and measured recorded high values in low frequencies.

  6. Introducing two Random Forest based methods for cloud detection in remote sensing images

    NASA Astrophysics Data System (ADS)

    Ghasemian, Nafiseh; Akhoondzadeh, Mehdi

    2018-07-01

    Cloud detection is a necessary phase in satellite images processing to retrieve the atmospheric and lithospheric parameters. Currently, some cloud detection methods based on Random Forest (RF) model have been proposed but they do not consider both spectral and textural characteristics of the image. Furthermore, they have not been tested in the presence of snow/ice. In this paper, we introduce two RF based algorithms, Feature Level Fusion Random Forest (FLFRF) and Decision Level Fusion Random Forest (DLFRF) to incorporate visible, infrared (IR) and thermal spectral and textural features (FLFRF) including Gray Level Co-occurrence Matrix (GLCM) and Robust Extended Local Binary Pattern (RELBP_CI) or visible, IR and thermal classifiers (DLFRF) for highly accurate cloud detection on remote sensing images. FLFRF first fuses visible, IR and thermal features. Thereafter, it uses the RF model to classify pixels to cloud, snow/ice and background or thick cloud, thin cloud and background. DLFRF considers visible, IR and thermal features (both spectral and textural) separately and inserts each set of features to RF model. Then, it holds vote matrix of each run of the model. Finally, it fuses the classifiers using the majority vote method. To demonstrate the effectiveness of the proposed algorithms, 10 Terra MODIS and 15 Landsat 8 OLI/TIRS images with different spatial resolutions are used in this paper. Quantitative analyses are based on manually selected ground truth data. Results show that after adding RELBP_CI to input feature set cloud detection accuracy improves. Also, the average cloud kappa values of FLFRF and DLFRF on MODIS images (1 and 0.99) are higher than other machine learning methods, Linear Discriminate Analysis (LDA), Classification And Regression Tree (CART), K Nearest Neighbor (KNN) and Support Vector Machine (SVM) (0.96). The average snow/ice kappa values of FLFRF and DLFRF on MODIS images (1 and 0.85) are higher than other traditional methods. The quantitative values on Landsat 8 images show similar trend. Consequently, while SVM and K-nearest neighbor show overestimation in predicting cloud and snow/ice pixels, our Random Forest (RF) based models can achieve higher cloud, snow/ice kappa values on MODIS and thin cloud, thick cloud and snow/ice kappa values on Landsat 8 images. Our algorithms predict both thin and thick cloud on Landsat 8 images while the existing cloud detection algorithm, Fmask cannot discriminate them. Compared to the state-of-the-art methods, our algorithms have acquired higher average cloud and snow/ice kappa values for different spatial resolutions.

  7. Predicted performance of a PG-SPECT system using CZT primary detectors and secondary Compton-suppression anti-coincidence detectors under near-clinical settings for boron neutron capture therapy

    NASA Astrophysics Data System (ADS)

    Hales, Brian; Katabuchi, Tatsuya; Igashira, Masayuki; Terada, Kazushi; Hayashizaki, Noriyosu; Kobayashi, Tooru

    2017-12-01

    A test version of a prompt-gamma single photon emission computed tomography (PG-SPECT) system for boron neutron capture therapy (BNCT) using a CdZnTe (CZT) semiconductor detector with a secondary BGO anti-Compton suppression detector has been designed. A phantom with healthy tissue region of pure water, and 2 tumor regions of 5 wt% borated polyethylene was irradiated to a fluence of 1.3 × 109 n/cm2. The number of 478 keV foreground, background, and net counts were measured for each detector position and angle. Using only experimentally measured net counts, an image of the 478 keV production from the 10B(n , α) 7Li* reaction was reconstructed. Using Monte Carlo simulation and the experimentally measured background counts, the reliability of the system under clinically accurate parameters was extrapolated. After extrapolation, it was found that the value of the maximum-value pixel in the reconstructed 478 keV γ-ray production image overestimates the simulated production by an average of 9.2%, and that the standard deviation associated with the same value is 11.4%.

  8. Quantification of plume opacity by digital photography.

    PubMed

    Du, Ke; Rood, Mark J; Kim, Byung J; Kemme, Michael R; Franek, Bill; Mattison, Kevin

    2007-02-01

    The United States Environmental Protection Agency (USEPA) developed Method 9 to describe how plume opacity can be quantified by humans. However, use of observations by humans introduces subjectivity, and is expensive due to semiannual certification requirements of the observers. The Digital Opacity Method (DOM) was developed to quantify plume opacity at lower cost, with improved objectivity, and to provide a digital record. Photographs of plumes were taken with a calibrated digital camera under specified conditions. Pixel values from those photographs were then interpreted to quantify the plume's opacity using a contrast model and a transmission model. The contrast model determines plume opacity based on pixel values that are related to the change in contrast between two backgrounds that are located behind and next to the plume. The transmission model determines the plume's opacity based on pixel values that are related to radiances from the plume and its background. DOM was field tested with a smoke generator. The individual and average opacity errors of DOM were within the USEPA Method 9 acceptable error limits for both field campaigns. Such results are encouraging and support the use of DOM as an alternative to Method 9.

  9. Economic value of in vitro fertilization in Ukraine, Belarus, and Kazakhstan

    PubMed Central

    Mandrik, Olena; Knies, Saskia; Severens, Johan L

    2015-01-01

    Background An economic value calculation was performed to estimate the lifetime net present value of in vitro fertilization (IVF) in Ukraine, Belarus, and Kazakhstan. Methods Net lifetime tax revenues were used to represent governmental benefits accruing from a hypothetical cohort of an IVF population born in 2009 using the methodology of generational accounting. Governmental expenses related to this population included social benefits, education and health care, unemployment support, and pensions. Where available, country-specific data referencing official sources were applied. Results The average health care cost needed to achieve one additional birth from the governmental perspective varied from $2,599 in Ukraine to $5,509 in Belarus. The net present value from the population born using IVF was positive in all countries: for Ukraine ($9,839), Belarus ($21,702), and Kazakhstan ($2,295). The break-even costs of drugs and supplies per IVF procedure is expected to be $3,870, $8,530, and $1,780, respectively. Probabilistic sensitivity analyses based on 5,000 simulations show that the average net present value per person remains positive: $1,894±$7,619, $27,925±$12,407, and $17,229±$24,637 in Ukraine, Belarus, and Kazakhstan, respectively. Conclusion Financing IVF may represent a good investment in terms of governmental financial returns, even in lower-income countries with state-financed health care systems such as Ukraine, Belarus, and Kazakhstan. PMID:26109873

  10. Analysis of diurnal variability of atmospheric halocarbons and CFC replacements to imply emission strength and sources at an urban site of Lukang in central Taiwan

    NASA Astrophysics Data System (ADS)

    Lee, Bing-Sun; Chiou, Chung-Biau; Lin, Chung-Yi

    2014-12-01

    Hourly atmospheric measurements of halocarbons and chlorofluorocarbon (CFC) replacements were conducted at an urban site of Lukang, Changhua, in central Taiwan from May to August, 2013. The temporal distribution of different groups of halocarbons in the Lukang urban atmosphere, including chlorofluorocarbons (CFCs), Chlorodifluoromethane (HCFC-22), Bromochlorodifluoromethane (Halon-1211), and other chlorinated compounds, is presented and discussed. The concentrations (mixing ratios) of HCFC-22, Dichlorodifluoromethane (CFC-12), Halon-1211, Trichlorofluoromethane (CFC-11), Dichloromethane (CH2Cl2), and Trichloroethylene (TCE) were enhanced with respect to the local background levels; the atmospheric mixing ratio of carbon tetrachloride (CCl4) was slightly higher than its local background level; on the other hand, 1,1,2-Trichlorotrifluoroethane (CFC-113) was relatively uniform and not very different from background atmospheric level in non-urban areas. Among these compounds, HCFC-22, Halon-1211 and the halogenated compounds, CH2Cl2 and TCE, used as solvents were strongly enhanced. The average mixing ratio of Halon-1211 was higher than the local background of ∼4.5 ppt by ∼60% although Halon-1211 production had been phased out by 1996. Hourly average mixing ratios of halocarbons (HCFC-22, CFC-12, Halon-1211, CFC-11, CH2Cl2, and TCE) illustrated a distinct diurnal cycle characterized with a pattern of elevated mixing ratio and large mixing ratio variability amplitude at night relative to that in daytime. Although emission sources of these halocarbons were complex, hourly average mixing ratios for most of these high variability halocarbons peaked at ∼5:00 AM when the hourly average wind speed reached the minimum value of the day; by contrast, the hourly average mixing ratio of CO peaked at ∼8:30 AM when the ambient atmospheric wind condition was strongly influenced by sea breezes during the traffic rush hours. This phenomenon revealed that meteorological factors predominated the distribution of halocarbon mixing ratio in the urban atmosphere and the traffic emission of CFC-12 derived from old vehicles manufactured before 1994 was insignificant to the CFC-12 mixing ratio in the urban atmosphere. The meteorological condition of nighttime atmospheric temperature inversion and low wind speed facilitated the accumulation of terrestrial airborne pollutants near the ground; consequently the hourly average mixing ratios at night were higher than those in daytime by up to ∼2% (CFC-11), ∼7% (CFC-12), ∼75% (HCFC-22), ∼72% (Halon-1211), ∼280% (CH2Cl2), and ∼155% (TCE).

  11. Exposure of bakery and pastry apprentices to airborne flour dust using PM2.5 and PM10 personal samplers

    PubMed Central

    Mounier-Geyssant, Estelle; Barthélemy, Jean-François; Mouchot, Lory; Paris, Christophe; Zmirou-Navier, Denis

    2007-01-01

    Background This study describes exposure levels of bakery and pastry apprentices to flour dust, a known risk factor of occupational asthma. Methods Questionnaires on work activity were completed by 286 students. Among them, 34 performed a series of two personal exposure measurements using a PM2.5 and PM10 personal sampler during a complete work shift, one during a cold ("winter") period, and the other during a hot ("summer") period. Results Bakery apprentices experience greater average PM2.5 and PM10 exposures than pastry apprentices (p < 0.006). Exposure values for both particulate fractions are greater in winter (average PM10 values among bakers = 1.10 mg.m-3 [standard deviation: 0.83]) than in summer (0.63 mg.m-3 [0.36]). While complying with current European occupational limit values, these exposures exceed the ACGIH recommendations set to prevent sensitization to flour dust (0.5 mg.m-3). Over half the facilities had no ventilation system. Conclusion Young bakery apprentices incur substantial exposure to known airways allergens, a situation that might elicit early induction of airways inflammation. PMID:17976230

  12. Degree-scale anisotropy in the cosmic microwave background: SP94 results

    NASA Technical Reports Server (NTRS)

    Gundersen, J. O.; Lim, M.; Staren, J.; Wuensche, C. A.; Figueiredo, N.; Gaier, T. C.; Koch, T.; Meinhold, P. R.; Seiffert, M. D.; Cook, G.

    1995-01-01

    We present results from two observations of the cosmic microwave background (CMB) performed from the South Pole during the 1993-1994 austral summer. Each observation employed a 3 deg peak-to-peak sinusoidal, single-difference chop and consisted of a 20 deg x 1 deg strip on the sky. The first observation used a receiver which operates in three channels between 38 and 45 GHz (Q-band) with a full width half maximum (FWHM) beam which varies from 1 deg to 1.15 deg. The second observation overlapped the first observation and used a receiver which operates in four channels between 26 and 36 GHz (Ka-band) with a FWHM beam which varies from 1.5 deg to 1.7 deg. Significant correlated structure is observed in all channels for each observation. The spectrum of the structure is consistent with a CMB spectrum and is formally inconsistent with diffuse synchrotron and free-free emission at the 5 sigma level. The amplitude of the structure is inconsistent with 20 K interstellar dust; however, the data do not discriminate against flat or inverted spectrum point sources. The root mean square amplitude (+/- 1 sigma) of the combined (Ka + Q) data is Delta T(sub rms) = 41.2(sup +15.5, sub -6.7) micro-K for an average window function which has a peak value of 0.97 at l = 68 and drops to e(exp -0.5) of the peak value at l = 36 and l = 106. A band power estimate of the CMB power spectrum, C(sub l), gives average value of (C(sub l)l(l + 1)/(2 pi))(sub B) = 1.77(sup +1.58, sub -0.54) x 10(exp -10).

  13. Investigation of the Relationship between Work Ability and Work-related Quality of Life in Nurses

    PubMed Central

    ABBASI, Milad; ZAKERIAN, Abolfazl; AKBARZADE, Arash; DINARVAND, Nader; GHALJAHI, Maryam; POURSADEGHIYAN, Mohsen; EBRAHIMI, Mohammad Hossein

    2017-01-01

    Background: Work ability of nurses is an index of their job satisfaction and is a crucial factor in job quality and security. This study aimed to investigate the association between work ability and quality of working life and to determine the effective demographic and background variables, among nurses. Methods: The present study was conducted among nurses, working in educational hospitals under the supervision of Tehran University of Medical Sciences in 2014. Work Ability Index (WAI) and Work-related Quality of Life (WRQoL) were used. Results: The mean WAI was significantly associated with total WRQoL score and the two of its sub-items including Stress at Work, and General Well-Being (P-value=0.001). Moreover, the results showed a significant correlation between total WRQoL and WAI Subscales including mental resources (P-value=0.001), number of current diseases (P-value=0.02), and work ability in relation to the job demands (P-value=0.04). The WRQoL and WAI showed significant associations with age and job experience (P-value=0.001). The average score of WAI and WRQoL was statistically different among various working units (P-value=0.001). Conclusion: Overall, results support the association between nurses work ability and WRQoL. Monitoring the WRQoL and work ability of employees would help organizations to know their status and take measures to ameliorate the working conditions. PMID:29308385

  14. Using Copulas in the Estimation of the Economic Project Value in the Mining Industry, Including Geological Variability

    NASA Astrophysics Data System (ADS)

    Krysa, Zbigniew; Pactwa, Katarzyna; Wozniak, Justyna; Dudek, Michal

    2017-12-01

    Geological variability is one of the main factors that has an influence on the viability of mining investment projects and on the technical risk of geology projects. In the current scenario, analyses of economic viability of new extraction fields have been performed for the KGHM Polska Miedź S.A. underground copper mine at Fore Sudetic Monocline with the assumption of constant averaged content of useful elements. Research presented in this article is aimed at verifying the value of production from copper and silver ore for the same economic background with the use of variable cash flows resulting from the local variability of useful elements. Furthermore, the ore economic model is investigated for a significant difference in model value estimated with the use of linear correlation between useful elements content and the height of mine face, and the approach in which model parameters correlation is based upon the copula best matched information capacity criterion. The use of copula allows the simulation to take into account the multi variable dependencies at the same time, thereby giving a better reflection of the dependency structure, which linear correlation does not take into account. Calculation results of the economic model used for deposit value estimation indicate that the correlation between copper and silver estimated with the use of copula generates higher variation of possible project value, as compared to modelling correlation based upon linear correlation. Average deposit value remains unchanged.

  15. Particulate sulphate and ozone in rural air: Preliminary results from three sites in central England

    NASA Astrophysics Data System (ADS)

    Martin, A.; Barber, F. R.

    Daily particulate sulphate concentrations in air have been measured at a 'background' rural site and at two other sites near rural power stations. The samples were collected by drawing air through filter papers and were analysed by X-ray fluorescence. At the background site the concentration of particulate sulphates was strongly dependent on the O 3 and total S in air. Above a certain 'critical' level of daily O 3, 28% of the daily S in air was particulate on average, but the amounts were not related to the actual O 3 levels. At lower O 3 levels, there appeared to be a constant background of about 2 μg of particulate sulphate per cubic meter of air, together with about 5% of the total S in air as particulate. When black smoke in air was low, the particulate sulphate was also low, despite the O 3 levels. Near the power stations, there was no significantly different rate of production or loss of particulate sulphate. On average, at all three sites over the year, about 12% of the daily total S was particulate, probably corresponding to an average conversion rate of SO 2 of less than 1% per hour. Estimates of hourly particulate sulphates are available from previous measurements at the background site, using a different analysis technique. Particulate sulphate was not found every hour, but typically during 20 h a day in early summer and 8 h a day in early winter. An influence of humidity as well as O 3 was apparent in the peak hourly particulate sulphate values, which reached 60% of the total S. No correlation could be found of particulate sulphate with solar radiation, wind direction, concentrations of oxides of nitrogen in air or ammonium or sulphate in rainwater, but further measurements are planned.

  16. Reprint of Mechanisms of maintaining high suspended sediment concentration over tide-dominated offshore shoals in the southern Yellow Sea

    NASA Astrophysics Data System (ADS)

    Xiong, Jilian; Wang, Xiao Hua; Wang, Ya Ping; Chen, Jingdong; Shi, Benwei; Gao, Jianhua; Yang, Yang; Yu, Qian; Li, Mingliang; Yang, Lei; Gong, Xulong

    2018-06-01

    An understanding of the dynamics and behaviors of suspended sediments is vital in analysis of morphological, environmental, and ecological processes occurring in coastal marine environments. To study the mechanisms of maintaining high suspended sediment concentrations (SSCs) on a tide-dominated offshore shoal, we measured water depths, current velocities, SSCs, wave parameters and bottom sediment compositions in the southern Yellow Sea. These data were then used to calculate bottom shear stresses generated by currents (τc), waves (τw), and wave-current interactions (τcw). SSCs time series exhibited strong quarter-diurnal peaks during spring tides, in contrast to the semidiurnal signal during neap tides. A Fourier analysis showed that suspended sediment variations within tidal cycles was mainly controlled by resuspension in most stations. There existed relatively stable background SSCs (maintaining high SSCs among tidal cycles) values at all four stations during both windy (wind speed > 9.0 m/s) and normal weather conditions (wind speed < 3.0 m/s). The background SSCs had strong relationship with spring/neap-averaged τcw, indicating background SSCs were mainly controlled by mean bottom shear stress, with a minimum value of 0.21 N/m2. On account of the strong tidal currents, background SSCs of spring tides were greater than that of neap tides. In addition, on the base of wavelet, statistics analyses and turbulence dissipation parameter, background SSCs during slack tide in the study area may be maintained by intermittent turbulence events induced by a combined tidal current and wave action.

  17. Mechanisms of maintaining high suspended sediment concentration over tide-dominated offshore shoals in the southern Yellow Sea

    NASA Astrophysics Data System (ADS)

    Xiong, Jilian; Wang, Xiao Hua; Wang, Ya Ping; Chen, Jingdong; Shi, Benwei; Gao, Jianhua; Yang, Yang; Yu, Qian; Li, Mingliang; Yang, Lei; Gong, Xulong

    2017-05-01

    An understanding of the dynamics and behaviors of suspended sediments is vital in analysis of morphological, environmental, and ecological processes occurring in coastal marine environments. To study the mechanisms of maintaining high suspended sediment concentrations (SSCs) on a tide-dominated offshore shoal, we measured water depths, current velocities, SSCs, wave parameters and bottom sediment compositions in the southern Yellow Sea. These data were then used to calculate bottom shear stresses generated by currents (τc), waves (τw), and wave-current interactions (τcw). SSCs time series exhibited strong quarter-diurnal peaks during spring tides, in contrast to the semidiurnal signal during neap tides. A Fourier analysis showed that suspended sediment variations within tidal cycles was mainly controlled by resuspension in most stations. There existed relatively stable background SSCs (maintaining high SSCs among tidal cycles) values at all four stations during both windy (wind speed > 9.0 m/s) and normal weather conditions (wind speed < 3.0 m/s). The background SSCs had strong relationship with spring/neap-averaged τcw, indicating background SSCs were mainly controlled by mean bottom shear stress, with a minimum value of 0.21 N/m2. On account of the strong tidal currents, background SSCs of spring tides were greater than that of neap tides. In addition, on the base of wavelet, statistics analyses and turbulence dissipation parameter, background SSCs during slack tide in the study area may be maintained by intermittent turbulence events induced by a combined tidal current and wave action.

  18. A liberal arts education as preparation for medical school: how is it valued? How do graduates perform?

    PubMed

    Stratton, Terry D; Elam, Carol L; McGrath, Michael G

    2003-10-01

    This study examines the utility of a liberal arts education on medical students' preparation and performance. Data included a survey of admission committee members, a preadmission survey of two cohorts of students, and academic performance and extracurricular involvement during medical school. Some admission committee members perceived applicants with liberal arts backgrounds to have certain advantages. These students preferred "discussing issues," and showed an initial preference for the practice of psychiatry. Despite entering with lower total grade-point average and being less involved in extracurricular activities, they were more likely to receive formal commendation and be elected to Alpha Omega Alpha. Although similarities outweigh differences, students with liberal arts backgrounds may benefit from an educational breadth well-suited for practicing the "art of medicine."

  19. Monte Carlo studies of thermalization of electron-hole pairs in spin-polarized degenerate electron gas in monolayer graphene

    NASA Astrophysics Data System (ADS)

    Borowik, Piotr; Thobel, Jean-Luc; Adamowicz, Leszek

    2018-02-01

    Monte Carlo method is applied to the study of relaxation of excited electron-hole (e-h) pairs in graphene. The presence of background of spin-polarized electrons, with high density imposing degeneracy conditions, is assumed. To such system, a number of e-h pairs with spin polarization parallel or antiparallel to the background is injected. Two stages of relaxation: thermalization and cooling are clearly distinguished when average particles energy < E> and its standard deviation σ _E are examined. At the very beginning of thermalization phase, holes loose energy to electrons, and after this process is substantially completed, particle distributions reorganize to take a Fermi-Dirac shape. To describe the evolution of < E > and σ _E during thermalization, we define characteristic times τ _ {th} and values at the end of thermalization E_ {th} and σ _ {th}. The dependence of these parameters on various conditions, such as temperature and background density, is presented. It is shown that among the considered parameters, only the standard deviation of electrons energy allows to distinguish between different cases of relative spin polarizations of background and excited electrons.

  20. Background radiation dose of dumpsites in Ota and Environs

    NASA Astrophysics Data System (ADS)

    Usikalu, M. R.; Ola, O. O.; Achuka, J. A.; Babarimisa, I. O.; Ayara, W. A.

    2017-05-01

    In-situ measurement of background radiation dose from selected dumpsites in Ota and its environs was done using Radialert Nuclear Radiation Monitor (Digilert 200). Ten measurements were taken from each dumpsite. The measured background radiation range between 0.015 mRhr-1 for AOD and 0.028 mRhr-1 for SUS dumpsites. The calculated annual equivalent doses vary between 1.31 mSvyr-1 for AOD and 2.28 mSv/yr for SUS dumpsites. The air absorbed dose calculated ranged from 150 nGyhr-1 to 280 nGy/hr for AOD and SUS dumpsites respectively with an average value of 217 nGyhr-1 for all the locations. All the estimated parameters were higher than permissible limit set for background radiation for the general public. Conclusively, the associated challenge and radiation burden posed by the wastes on the studied locations and scavengers is high. Therefore, there is need by the regulatory authorities to look into the way and how waste can be properly managed so as to alleviate the effects on the populace leaving and working in the dumpsites vicinity.

  1. Object Detection in Natural Backgrounds Predicted by Discrimination Performance and Models

    NASA Technical Reports Server (NTRS)

    Ahumada, A. J., Jr.; Watson, A. B.; Rohaly, A. M.; Null, Cynthia H. (Technical Monitor)

    1995-01-01

    In object detection, an observer looks for an object class member in a set of backgrounds. In discrimination, an observer tries to distinguish two images. Discrimination models predict the probability that an observer detects a difference between two images. We compare object detection and image discrimination with the same stimuli by: (1) making stimulus pairs of the same background with and without the target object and (2) either giving many consecutive trials with the same background (discrimination) or intermixing the stimuli (object detection). Six images of a vehicle in a natural setting were altered to remove the vehicle and mixed with the original image in various proportions. Detection observers rated the images for vehicle presence. Discrimination observers rated the images for any difference from the background image. Estimated detectabilities of the vehicles were found by maximizing the likelihood of a Thurstone category scaling model. The pattern of estimated detectabilities is similar for discrimination and object detection, and is accurately predicted by a Cortex Transform discrimination model. Predictions of a Contrast- Sensitivity- Function filter model and a Root-Mean-Square difference metric based on the digital image values are less accurate. The discrimination detectabilities averaged about twice those of object detection.

  2. GOSAT observations of anthropogenic emission of carbon dioxide and methane

    NASA Astrophysics Data System (ADS)

    Janardanan, Rajesh; Maksyutov, Shamil; Oda, Tomohiro; Saito, Makoto; Ito, Akihiko; Kaiser, Johannes W.; Ganshin, Alexander; Yoshida, Yukio; Yokota, Tatsuya; Matsunaga, Tsuneo

    2017-04-01

    Carbon dioxide (CO2) and methane (CH4) are the most important greenhouse gases in terms of radiative forcing. Human activities such as combustion of fossil fuel (for CO2), and gas leakage, animal agriculture, rice cultivation and landfill emissions (for CH4), are considered to be major sources of their emissions. Global emissions datasets usually depend on emission estimates reported by countries, which are seldom evaluated in an objective way. Here we present a method for delineating anthropogenic contributions to global atmospheric CO2 and CH4 (2009-2014) concentration fields using GOSAT observations of column-average dry air mole fractions (XCO2 and XCH4) and atmospheric transport model simulations using high-resolution emissions datasets (ODIAC for CO2 and EDGAR for CH4). The XCO2 and XCH4 concentration enhancements due to anthropogenic emissions are estimated at all GOSAT observation locations using the transport model simulation. We calculated threshold values to classify GOSAT observations into two categories: (1) data influenced by the anthropogenic sources and (2) those not influenced. We defined a clean background (averaged concentrations of GOSAT data that are free from contamination) in 10˚ ×10˚ regions over the globe and subtracted the background values from individual GOSAT observations. The anomalies (GOSAT observed values minus background values) were binned and compared to model-based anomalies over continental regions and selected countries. For CO2, we have found global and regional linear relationships between model and observed anomalies especially for Eurasia and North America. The analysis for East Asian region showed a systematic bias that is somewhat comparable in magnitude to the uncertainties in emission inventories in that region, which were reported by recent studies. In the case of CH4, we found a good match between inventory-based estimates and GOSAT observations for continental regions and large countries. The inventory-based estimate over North American region is biased which is in agreement with recent studies. Currently, our method is limited by the numbers of GOSAT observations available. If sufficient numbers of satellite observations are available from a instrument like GOSAT, our method could be a useful tool for monitoring greenhouse gas emissions using the regression slope between modeled and observed anomalies as a correction factor for nationally reported emissions.

  3. Issues and progress in determining background ozone and particle concentrations

    NASA Astrophysics Data System (ADS)

    Pinto, J. P.

    2011-12-01

    Exposure to ambient ozone is associated with a variety of health outcomes ranging from mild breathing discomfort to mortality. For the purpose of health risk and policy assessments EPA evaluates the anthropogenic increase in ozone above background concentrations and has defined the North American (NA) background concentration of O3 as that which would occur in the U.S. in the absence of anthropogenic emissions of precursors in the U.S., Canada, and Mexico. Monthly average NA background ozone has been used to evaluate health risks, but EPA and state air quality managers must also estimate day specific ozone background levels for high ozone episodes as part of urban scale photochemical modeling efforts to support ozone regulatory programs. The background concentration of O3 is of more concern than other air pollutants because it typically represents a much larger fraction of observed O3 than do the backgrounds of other criteria pollutants (particulate matter (PM), CO, NO2, SO2). NA background cannot be determined directly from ambient monitoring data because of the influence of NA precursor emissions on formation of ozone within NA. Instead, estimates of NA background O3 have been based on GEOS-Chem using simulations in which NA anthropogenic precursor emissions are zeroed out. Thus, modeled NA background O3 includes contributions from natural sources of precursors (including CH4, NMVOCs, NOx, and CO) everywhere in the world, anthropogenic sources of precursors outside of NA, and downward transport of O3 from the stratosphere. Although monitoring data cannot determine NA background directly, measurements by satellites, aircraft, ozonesondes and surface monitors have proved to be highly useful for identifying sources of background O3 and for evaluating the performance of the GEOS-Chem model. Model simulated NA background concentrations are strong functions of location and season with large inter-day variability and with values increasing with elevation and higher in spring than in summer, and tend to be highest in the Intermountain West during spring. Estimates of annual average NA and other background definitions that have been considered will be presented. Issues associated with modeling background concentrations for both health-risk assessments and for episodic regulatory air quality programs will be discussed, and proposals for new atmospheric measurements and model improvements needed to quantify more accurately background contributions to ozone will also be presented. The views expressed are those of the author and do not necessarily represent the views or policies of the U.S. Environmental Protection Agency.

  4. Temporal dynamics of CO2 fluxes and profiles over a Central European city

    NASA Astrophysics Data System (ADS)

    Vogt, R.; Christen, A.; Rotach, M. W.; Roth, M.; Satyanarayana, A. N. V.

    2006-02-01

    In Summer 2002 eddy covariance flux measurements of CO2 were performed over a dense urban surface. The month-long measurements were carried out in the framework of the Basel Urban Boundary Layer Experiment (BUBBLE). Two Li7500 open path analysers were installed at z/z H = 1.0 and 2.2 above a street canyon with z H the average building height of 14.6 m and z the height above street level. Additionally, profiles of CO2 concentration were sampled at 10 heights from street level up to 2 z H . The minimum and maximum of the average diurnal course of CO2 concentration at 2 z H were 362 and 423 ppmv in late afternoon and early morning, respectively. Daytime CO2 concentrations were not correlated to local sources, e.g. the minimum occurred together with the maximum in traffic load. During night-time CO2 is in general accumulated, except when inversion development is suppressed by frontal passages. CO2 concentrations were always decreasing with height and correspondingly, the fluxes on average always directed upward. At z/z H = 2.2 low values of about 3 µmol m-2 s-1 were measured during the second half of the night. During daytime average values reached up to 14 µmol m-2 s-1. The CO2 fluxes are well correlated with the traffic load, with their maxima occurring together in late afternoon. Daytime minimum CO2 concentrations fell below regional background values. Besides vertical mixing and entrainment, it is suggested that this is also due to advection of rural air with reduced CO2 concentration. Comparison with other urban observations shows a large range of differences among urban sites in terms of both CO2 fluxes and concentrations.

  5. Cross-shift changes in FEV1 in relation to wood dust exposure: the implications of different exposure assessment methods

    PubMed Central

    Schlunssen, V; Sigsgaard, T; Schaumburg, I; Kromhout, H

    2004-01-01

    Background: Exposure-response analyses in occupational studies rely on the ability to distinguish workers with regard to exposures of interest. Aims: To evaluate different estimates of current average exposure in an exposure-response analysis on dust exposure and cross-shift decline in FEV1 among woodworkers. Methods: Personal dust samples (n = 2181) as well as data on lung function parameters were available for 1560 woodworkers from 54 furniture industries. The exposure to wood dust for each worker was calculated in eight different ways using individual measurements, group based exposure estimates, a weighted estimate of individual and group based exposure estimates, and predicted values from mixed models. Exposure-response relations on cross-shift changes in FEV1 and exposure estimates were explored. Results: A positive exposure-response relation between average dust exposure and cross-shift FEV1 was shown for non-smokers only and appeared to be most pronounced among pine workers. In general, the highest slope and standard error (SE) was revealed for grouping by a combination of task and factory size, the lowest slope and SE was revealed for estimates based on individual measurements, with the weighted estimate and the predicted values in between. Grouping by quintiles of average exposure for task and factory combinations revealed low slopes and high SE, despite a high contrast. Conclusion: For non-smokers, average dust exposure and cross-shift FEV1 were associated in an exposure dependent manner, especially among pine workers. This study confirms the consequences of using different exposure assessment strategies studying exposure-response relations. It is possible to optimise exposure assessment combining information from individual and group based exposure estimates, for instance by applying predicted values from mixed effects models. PMID:15377768

  6. Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population.

    PubMed

    Ivannikov, Alexander I; Khailov, Artem M; Orlenko, Sergey P; Skvortsov, Valeri G; Stepanenko, Valeri F; Zhumadilov, Kassym Sh; Williams, Benjamin B; Flood, Ann B; Swartz, Harold M

    2016-12-01

    The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y -1 , the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose-response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its variation correspond to 4.0 ± 0.4 (SD = 1.0) Gy. © Crown copyright 2016.

  7. Determination of the Average Native Background and the Light-Induced EPR Signals and their Variation in the Teeth Enamel Based on Large-Scale Survey of the Population

    PubMed Central

    Ivannikov, Alexander I.; Khailov, Artem M.; Orlenko, Sergey P.; Skvortsov, Valeri G.; Stepanenko, Valeri F.; Zhumadilov, Kassym Sh.; Williams, Benjamin B.; Flood, Ann B.; Swartz, Harold M.

    2016-01-01

    The aim of the study is to determine the average intensity and variation of the native background signal amplitude (NSA) and of the solar light-induced signal amplitude (LSA) in electron paramagnetic resonance (EPR) spectra of tooth enamel for different kinds of teeth and different groups of people. These values are necessary for determination of the intensity of the radiation-induced signal amplitude (RSA) by subtraction of the expected NSA and LSA from the total signal amplitude measured in L-band for in vivo EPR dosimetry. Variation of these signals should be taken into account when estimating the uncertainty of the estimated RSA. A new analysis of several hundred EPR spectra that were measured earlier at X-band in a large-scale examination of the population of the Central Russia was performed. Based on this analysis, the average values and the variation (standard deviation, SD) of the amplitude of the NSA for the teeth from different positions, as well as LSA in outer enamel of the front teeth for different population groups, were determined. To convert data acquired at X-band to values corresponding to the conditions of measurement at L-band, the experimental dependencies of the intensities of the RSA, LSA and NSA on the m.w. power, measured at both X and L-band, were analysed. For the two central upper incisors, which are mainly used in in vivo dosimetry, the mean LSA annual rate induced only in the outer side enamel and its variation were obtained as 10 ± 2 (SD = 8) mGy y−1, the same for X- and L-bands (results are presented as the mean ± error of mean). Mean NSA in enamel and its variation for the upper incisors was calculated at 2.0 ± 0.2 (SD = 0.5) Gy, relative to the calibrated RSA dose–response to gamma radiation measured under non-power saturation conditions at X-band. Assuming the same value for L-band under non-power saturating conditions, then for in vivo measurements at L-band at 25 mW (power saturation conditions), a mean NSA and its variation correspond to 4.0 ± 0.4 (SD = 1.0) Gy. PMID:27412516

  8. [Rare earth elements content in farmland soils and crops of the surrounding copper mining and smelting plant in Jiangxi province and evaluation of its ecological risk].

    PubMed

    Jin, Shu-Lan; Huang, Yi-Zong; Wang, Fei; Xu, Feng; Wang, Xiao-Ling; Gao, Zhu; Hu, Ying; Qiao Min; Li, Jin; Xiang, Meng

    2015-03-01

    Rare earth elements content in farmland soils and crops of the surrounding copper mining and smelting plant in Jiangxi province was studied. The results showed that copper mining and smelting could increase the content of rare earth elements in soils and crops. Rare earth elements content in farmland soils of the surrounding Yinshan Lead Zinc Copper Mine and Guixi Smelting Plant varied from 112.42 to 397.02 mg x kg(-1) and 48.81 to 250.06 mg x kg(-1), and the average content was 254.84 mg x kg(-1) and 144.21 mg x kg(-1), respectively. The average contents of rare earth elements in soils in these two areas were 1.21 times and 0.68 times of the background value in Jiangxi province, 1.36 times and 0.77 times of the domestic background value, 3.59 times and 2.03 times of the control samples, respectively. Rare earth elements content in 10 crops of the surrounding Guixi Smelting Plant varied from 0.35 to 2.87 mg x kg(-1). The contents of rare earth elements in the leaves of crops were higher than those in stem and root. The contents of rare earth elements in Tomato, lettuce leaves and radish leaves were respectively 2.87 mg x kg(-1), 1.58 mg x kg(-1) and 0.80 mg x kg(-1), which were well above the hygienic standard limit of rare earth elements in vegetables and fruits (0.70 mg x kg(-1)). According to the health risk assessment method recommended by America Environmental Protection Bureau (USEPA), we found that the residents' lifelong average daily intake of rare earth elements was 17.72 mg x (kg x d)(-1), lower than the critical value of rare earth elements damage to human health. The results suggested that people must pay attention to the impact of rare earth elements on the surrounding environment when they mine and smelt copper ore in Jiangxi.

  9. A novel DTI-QA tool: Automated metric extraction exploiting the sphericity of an agar filled phantom.

    PubMed

    Chavez, Sofia; Viviano, Joseph; Zamyadi, Mojdeh; Kingsley, Peter B; Kochunov, Peter; Strother, Stephen; Voineskos, Aristotle

    2018-02-01

    To develop a quality assurance (QA) tool (acquisition guidelines and automated processing) for diffusion tensor imaging (DTI) data using a common agar-based phantom used for fMRI QA. The goal is to produce a comprehensive set of automated, sensitive and robust QA metrics. A readily available agar phantom was scanned with and without parallel imaging reconstruction. Other scanning parameters were matched to the human scans. A central slab made up of either a thick slice or an average of a few slices, was extracted and all processing was performed on that image. The proposed QA relies on the creation of two ROIs for processing: (i) a preset central circular region of interest (ccROI) and (ii) a signal mask for all images in the dataset. The ccROI enables computation of average signal for SNR calculations as well as average FA values. The production of the signal masks enables automated measurements of eddy current and B0 inhomogeneity induced distortions by exploiting the sphericity of the phantom. Also, the signal masks allow automated background localization to assess levels of Nyquist ghosting. The proposed DTI-QA was shown to produce eleven metrics which are robust yet sensitive to image quality changes within site and differences across sites. It can be performed in a reasonable amount of scan time (~15min) and the code for automated processing has been made publicly available. A novel DTI-QA tool has been proposed. It has been applied successfully on data from several scanners/platforms. The novelty lies in the exploitation of the sphericity of the phantom for distortion measurements. Other novel contributions are: the computation of an SNR value per gradient direction for the diffusion weighted images (DWIs) and an SNR value per non-DWI, an automated background detection for the Nyquist ghosting measurement and an error metric reflecting the contribution of EPI instability to the eddy current induced shape changes observed for DWIs. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Association of udder traits with single nucleotide polymorphisms in crossbred Bos indicus-Bos taurus cows.

    PubMed

    Tolleson, M W; Gill, C A; Herring, A D; Riggs, P K; Sawyer, J E; Sanders, J O; Riley, D G

    2017-06-01

    The size, support, and health of udders limit the productive life of beef cows, especially those with background, because, in general, such cows have a reputation for problems with udders. Genomic association studies of bovine udder traits have been conducted in dairy cattle and recently in Continental European beef breeds but not in cows with background. The objective of this study was to determine associations of SNP and udder support scores, teat length, and teat diameter in half (Nellore), half (Angus) cows. Udders of cows ( = 295) born from 2003 to 2007 were evaluated for udder support and teat length and diameter ( = 1,746 records) from 2005 through 2014. These included a subjective score representing udder support (values of 1 indicated poorly supported, pendulous udders and values of 9 indicated very well-supported udders) and lengths and diameters of individual teats in the 4 udder quarters as well as the average. Cows were in full-sibling or half-sibling families. Residuals for each trait were produced from repeated records models with cow age category nested within birth year of cows. Those residuals were averaged to become the dependent variables for genomewide association analyses. Regression analyses of those dependent variables included genotypic values as explanatory variables for 34,980 SNP from a commercially available array and included the genomic relationship matrix. Fifteen SNP loci on BTA 5 were associated (false discovery rate controlled at 0.05) with udder support score. One of those was also detected as associated with average teat diameter. Three of those 15 SNP were located within genes, including one each in (), (), and (). These are notable for their functional role in some aspect of mammary gland formation or health. Other candidate genes for these traits in the vicinity of the SNP loci include () and (). Because these were detected in Nellore-Angus crossbred cows, which typically have very well-formed udders with excellent support across their productive lives, similar efforts in other breeds should be completed, because that may facilitate further refinement of genomic regions responsible for variation in udder traits important in multiple breeds.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lavinto, Mikko; Räsänen, Syksy; Szybka, Sebastian J., E-mail: mikko.lavinto@helsinki.fi, E-mail: syksy.rasanen@iki.fi, E-mail: sebastian.szybka@uj.edu.pl

    We construct the first exact statistically homogeneous and isotropic cosmological solution in which inhomogeneity has a significant effect on the expansion rate. The universe is modelled as a Swiss Cheese, with dust FRW background and inhomogeneous holes. We show that if the holes are described by the quasispherical Szekeres solution, their average expansion rate is close to the background under certain rather general conditions. We specialise to spherically symmetric holes and violate one of these conditions. As a result, the average expansion rate at late times grows relative to the background, \\ie backreaction is significant. The holes fit smoothly intomore » the background, but are larger on the inside than a corresponding background domain: we call them Tardis regions. We study light propagation, find the effective equations of state and consider the relation of the spatially averaged expansion rate to the redshift and the angular diameter distance.« less

  12. Cytokinesis-block micronucleus cytome assay parameters in peripheral blood lymphocytes of the general population: Contribution of age, sex, seasonal variations and lifestyle factors.

    PubMed

    Gajski, Goran; Gerić, Marko; Oreščanin, Višnja; Garaj-Vrhovac, Vera

    2018-02-01

    The cytokinesis-block micronucleus cytome (CBMN Cyt) assay was used to evaluate the baseline frequency of cytogenetic damage in peripheral blood lymphocytes of the general population (average age, 38.28 ± 12.83 years) in relation to age, sex, body mass index, seasonal variations (season of sampling, period of sampling and different meteorological parameters) and lifestyle factors (smoking habit, alcohol consumption, exposure to medications and diagnostic radiation, physical activity, and family history of cancer). The background frequency of micronuclei (MNi) for the 200 subjects assayed was 5.06 ± 3.11 per 1000 binucleated cells, while the mean frequency of nucleoplasmic bridges (NPBs) was 1.21 ± 1.46 and of nuclear buds (NBUDs) 3.48 ± 2.14. The background frequency of apoptosis and necrosis was 1.58 ± 1.50 and 1.39 ± 1.56, respectively, while the mean nuclear division index (NDI) was 1.99 ± 0.14. The cut-off value, which corresponds to the 95th percentile of the distribution of 200 individual values, was 11 MNi, 4 NPBs and 7 NBUDs. The study also confirmed an association of the above mentioned parameters with age, sex and several lifestyle factors. Moreover, significant confounders based on our results are also sampling season, sampling period and different meteorological parameters that were dependent on the CBMN Cyt assay parameters. In line with the above mentioned, several factors should be taken into account when it comes to the monitoring of exposed populations using cytogenetic biomarkers. Moreover, the normal and cut-off values obtained in this study present background data for the general population, and can later serve as baseline values for further biomonitoring studies. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. TeO$$_2$$ bolometers with Cherenkov signal tagging: towards next-generation neutrinoless double-beta decay experiments

    DOE PAGES

    Casali, N.; Vignati, Marco; Beeman, J. W.; ...

    2015-01-14

    CUORE, an array of 988 TeOmore » $$_2$$ bolometers, is about to be one of the most sensitive experiments searching for neutrinoless double-beta decay. Its sensitivity could be further improved by removing the background from α radioactivity. A few years ago it was pointed out that the signal from βs can be tagged by detecting the emitted Cherenkov light, which is not produced by αs. In this paper we confirm this possibility. For the first time we measured the Cherenkov light emitted by a CUORE crystal, and found it to be 100 eV at the Q-value of the decay. To completely reject the α background, we compute that one needs light detectors with baseline noise below 20 eV RMS, a value which is 3–4 times smaller than the average noise of the bolometric light detectors we are using. We point out that an improved light detector technology must be developed to obtain TeO$$_2$$ bolometric experiments able to probe the inverted hierarchy of neutrino masses.« less

  14. Use of sediment-trace element geochemical models for the identification of local fluvial baseline concentrations

    USGS Publications Warehouse

    Horowitz, A.J.; Elrick, K.A.; Demas, C.R.; Demcheck, D.K.

    1991-01-01

    Studies have demonstrated the utility of fluvial bed sediment chemical data in assesing local water-quality conditions. However, establishing local background trace element levels can be difficult. Reference to published average concentrations or the use of dated cores are often of little use in small areas of diverse local petrology, geology, land use, or hydrology. An alternative approach entails the construction of a series of sediment-trace element predictive models based on data from environmentally diverse but unaffected areas. Predicted values could provide a measure of local background concentrations and comparison with actual measured concentrations could identify elevated trace elements and affected sites. Such a model set was developed from surface bed sediments collected nationwide in the United States. Tests of the models in a small Louisiana basin indicated that they could be used to establish local trace element background levels, but required recalibration to account for local geochemical conditions outside the range of samples used to generate the nationwide models.

  15. A testable model of earthquake probability based on changes in mean event size

    NASA Astrophysics Data System (ADS)

    Imoto, Masajiro

    2003-02-01

    We studied changes in mean event size using data on microearthquakes obtained from a local network in Kanto, central Japan, from a viewpoint that a mean event size tends to increase as the critical point is approached. A parameter describing changes was defined using a simple weighting average procedure. In order to obtain the distribution of the parameter in the background, we surveyed values of the parameter from 1982 to 1999 in a 160 × 160 × 80 km volume. The 16 events of M5.5 or larger in this volume were selected as target events. The conditional distribution of the parameter was estimated from the 16 values, each of which referred to the value immediately prior to each target event. The distribution of the background becomes a function of symmetry, the center of which corresponds to no change in b value. In contrast, the conditional distribution exhibits an asymmetric feature, which tends to decrease the b value. The difference in the distributions between the two groups was significant and provided us a hazard function for estimating earthquake probabilities. Comparing the hazard function with a Poisson process, we obtained an Akaike Information Criterion (AIC) reduction of 24. This reduction agreed closely with the probability gains of a retrospective study in a range of 2-4. A successful example of the proposed model can be seen in the earthquake of 3 June 2000, which is the only event during the period of prospective testing.

  16. Space Shuttle Main Engine Propellant Path Leak Detection Using Sequential Image Processing

    NASA Technical Reports Server (NTRS)

    Smith, L. Montgomery; Malone, Jo Anne; Crawford, Roger A.

    1995-01-01

    Initial research in this study using theoretical radiation transport models established that the occurrence of a leak is accompanies by a sudden but sustained change in intensity in a given region of an image. In this phase, temporal processing of video images on a frame-by-frame basis was used to detect leaks within a given field of view. The leak detection algorithm developed in this study consists of a digital highpass filter cascaded with a moving average filter. The absolute value of the resulting discrete sequence is then taken and compared to a threshold value to produce the binary leak/no leak decision at each point in the image. Alternatively, averaging over the full frame of the output image produces a single time-varying mean value estimate that is indicative of the intensity and extent of a leak. Laboratory experiments were conducted in which artificially created leaks on a simulated SSME background were produced and recorded from a visible wavelength video camera. This data was processed frame-by-frame over the time interval of interest using an image processor implementation of the leak detection algorithm. In addition, a 20 second video sequence of an actual SSME failure was analyzed using this technique. The resulting output image sequences and plots of the full frame mean value versus time verify the effectiveness of the system.

  17. Noise level in a neonatal intensive care unit in Santa Marta - Colombia.

    PubMed Central

    Garrido Galindo, Angélica Patricia; Velez-Pereira, Andres M

    2017-01-01

    Abstract Introduction: The environment of neonatal intensive care units is influenced by numerous sources of noise emission, which contribute to raise the noise levels, and may cause hearing impairment and other physiological and psychological changes on the newborn, as well as problems with care staff. Objective: To evaluate the level and sources of noise in the neonatal intensive care unit. Methods: Sampled for 20 consecutive days every 60 seconds in A-weighting curves and fast mode with a Type I sound level meter. Recorded the average, maximum and minimum, and the 10th, 50th and 90th percentiles. The values are integrated into hours and work shift, and studied by analysis of variance. The sources were characterized in thirds of octaves. Results: The average level was 64.00 ±3.62 dB(A), with maximum of 76.04 ±5.73 dB(A), minimum of 54.84 ±2.61dB(A), and background noise of 57.95 ±2.83 dB(A). We found four sources with levels between 16.8-63.3 dB(A). Statistical analysis showed significant differences between the hours and work shift, with higher values in the early hours of the day. Conclusion: The values presented exceed the standards suggested by several organizations. The sources identified and measured recorded high values in low frequencies. PMID:29213154

  18. Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

    PubMed Central

    HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

    2013-01-01

    Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure. PMID:23967422

  19. Flavour and identification threshold detection overview of Slovak adepts for certified testing.

    PubMed

    Vietoris, VladimIr; Barborova, Petra; Jancovicova, Jana; Eliasova, Lucia; Karvaj, Marian

    2016-07-01

    During certification process of sensory assessors of Slovak certification body we obtained results for basic taste thresholds and lifestyle habits. 500 adult people were screened during experiment with food industry background. For analysis of basic and non basic tastes, we used standardized procedure of ISO 8586-1:1993. In flavour test experiment, group of (26-35 y.o) produced the lowest error ratio (1.438), highest is (56+ y.o.) group with result (2.0). Average error value based on gender for women was (1.510) in comparison to men (1.477). People with allergies have the average error ratio (1.437) in comparison to people without allergies (1.511). Non-smokers produced less errors (1.484) against the smokers (1.576). Another flavour threshold identification test detected differences among age groups (by age are values increased). The highest number of errors made by men in metallic taste was (24%) the same as made by women (22%). Higher error ratio made by men occurred in salty taste (19%) against women (10%). Analysis detected some differences between allergic/non-allergic, smokers/non-smokers groups.

  20. Determination of pesticide residues in samples of green minor crops by gas chromatography and ultra performance liquid chromatography coupled to tandem quadrupole mass spectrometry.

    PubMed

    Walorczyk, Stanisław; Drożdżyński, Dariusz; Kierzek, Roman

    2015-01-01

    A method was developed for pesticide analysis in samples of high chlorophyll content belonging to the group of minor crops. A new type of sorbent, known as ChloroFiltr, was employed for dispersive-solid phase extraction cleanup (dispersive-SPE) to reduce the unwanted matrix background prior to concurrent analysis by gas chromatography and ultra-performance liquid chromatography coupled to tandem quadrupole mass spectrometry (GC-MS/MS and UPLC-MS/MS). Validation experiments were carried out on green, unripe plants of lupin, white mustard and sorghum. The overall recoveries at the three spiking levels of 0.01, 0.05 and 0.5 mg kg(-1) fell in the range between 68 and 120% (98% on average) and 72-104% (93% on average) with relative standard deviation (RSD) values between 2 and 19% (7% on average) and 3-16% (6% on average) by GC-MS/MS and UPLC-MS/MS technique, respectively. Because of strong enhancement or suppression matrix effects (absolute values >20%) which were exhibited by about 80% of the pesticide and matrix combinations, acceptably accurate quantification was achieved by using matrix-matched standards. Up to now, the proposed method has been successfully used to study the dissipation patterns of pesticides after application on lupin, white mustard, soya bean, sunflower and field bean in experimental plot trials conducted in Poland. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Level and Contamination Assessment of Soil along an Expressway in an Ecologically Valuable Area in Central Poland

    PubMed Central

    Radziemska, Maja; Fronczyk, Joanna

    2015-01-01

    Express roads are a potential source of heavy metal contamination in the surrounding environment. The Warsaw Expressway (E30) is one of the busiest roads in the capital of Poland and cuts through the ecologically valuable area (Mazowiecki Natural Landscape Park). Soil samples were collected at distances of 0.5, 4.5 and 25 m from the expressway. The concentrations of cadmium (Cd), copper (Cu), nickel (Ni), lead (Pb), and zinc (Zn) were determined in the soils by the flame atomic absorption spectrometry method (FAAS). Soils located in the direct proximity of the analyzed stretch of road were found to have the highest values of pH and electrical conductivity (EC), which decreased along with an increase in the distance from the expressway. The contents of Cd, Cu and Zn were found to be higher than Polish national averages, whereas the average values of Ni and Pb were not exceeded. The pollution level was estimated based on the geo-accumulation index (Igeo), and the pollution index (PI). The results of Igeo and PI indexes revealed the following orders: Cu < Zn < Ni < Cd < Pb and Cu < Ni < Cd < Zn < Pb, and comparison with geochemical background values showed higher concentration of zinc, lead and cadmium. PMID:26512684

  2. Level and Contamination Assessment of Soil along an Expressway in an Ecologically Valuable Area in Central Poland.

    PubMed

    Radziemska, Maja; Fronczyk, Joanna

    2015-10-23

    Express roads are a potential source of heavy metal contamination in the surrounding environment. The Warsaw Expressway (E30) is one of the busiest roads in the capital of Poland and cuts through the ecologically valuable area (Mazowiecki Natural Landscape Park). Soil samples were collected at distances of 0.5, 4.5 and 25 m from the expressway. The concentrations of cadmium (Cd), copper (Cu), nickel (Ni), lead (Pb), and zinc (Zn) were determined in the soils by the flame atomic absorption spectrometry method (FAAS). Soils located in the direct proximity of the analyzed stretch of road were found to have the highest values of pH and electrical conductivity (EC), which decreased along with an increase in the distance from the expressway. The contents of Cd, Cu and Zn were found to be higher than Polish national averages, whereas the average values of Ni and Pb were not exceeded. The pollution level was estimated based on the geo-accumulation index (Igeo), and the pollution index (PI). The results of Igeo and PI indexes revealed the following orders: Cu < Zn < Ni < Cd < Pb and Cu < Ni < Cd < Zn < Pb, and comparison with geochemical background values showed higher concentration of zinc, lead and cadmium.

  3. Contemporary skull development - palatal angle analysis.

    PubMed

    Dostalova, T; Eliasova, H; Gabcova, D; Feberova, J; Kaminek, M

    2015-01-01

    The palatal angle is an important angle of the craniofacial complex. It is significant for the diagnosis of craniofacial disorders mainly for nasopharyngeal soft-tissue patterns.Background The dentists and otorhinolaryngologists use this relationship to establish proper treatment mechanics and evaluate facial profile. The aims of this study were to provide comparative cephalometric analyses of historical and contemporary skulls. A total of 190 cephalograms of 2 groups of subjects were evaluated. Dolphin Imaging 11.0 - Cephalometric Tracing Analysis was used for the analysis. Unpaired two-tailed t-test assuming equality of variances was used for all variables (at the significance level p = 0.0001). The -modern forensic skulls had larger palatal angle at average value of 8.60 degrees ± 4.35, than that of archeological ones, the average value of which was 6.50 degrees ± 3.92. The difference was found significant. Unpaired two-tailed t-test assuming equality of variances showed that historical and contemporary skulls had statistically significant results. The difference was -2.09 with standard error of 0.60 (95% confidence interval from -3.29 to -0.89). Two-tailed probability attained value of P was less than 0.0001. The difference between both groups was found significant. An increase in the palatal angle can be directly connected with anterior rotation of upper jaw(Tab. 2, Fig. 5, Ref. 19).

  4. Diffuse CO2 degassing monitoring for the volcanic surveillance of Tenerife North-East Rift Zone (NERZ) volcano, Canary Islands

    NASA Astrophysics Data System (ADS)

    Rodríguez, F.; Thomas, G. E.; Wong, T.; García, E.; Melián, G.; Padron, E.; Asensio-Ramos, M.; Hernández, P. A.; Perez, N. M.

    2017-12-01

    The North East Rift zone of Tenerife Island (NERZ, 210 km2) is one of the three major volcanic rift-zones of the island. The most recent eruptive activity along the NERZ took place in the 1704-1705 period with eruptions of Siete Fuentes, Fasnia and Arafo volcanoes. Since fumarolic activity is nowadays absent at the NERZ, soil CO2 degassing monitoring represent a potential geochemical tool for its volcanic surveillance. The aim of this study is to report the results of the last CO2 efflux survey performed in June 2017, with 658 sampling sites. In-situ measurements of CO2 efflux from the surface environment of the NERZ were performed by means of a portable non-dispersive infrared spectrophotometer (NDIR) following the accumulation chamber method. To quantify the total CO2 emission, soil CO2 efflux spatial distribution maps were constructed using Sequential Gaussian Simulation (SGS) as interpolation method. The diffuse CO2 emission values ranged between 0 - 41.1 g m-2 d-1. The probability plot technique applied to the data allowed to distinguish two different geochemical populations; background (B) and peak (P) represented by 81.8% and 18.2% of the total data, respectively, with geometric means of 3.9 and 15.0 g m-2 d-1, respectively. The average map constructed with 100 equiprobable simulations showed an emission rate of 1,361±35 t d-1. This value relatively higher than the background average of CO2 emission estimated on 415 t d-1 and slightly higher than the background range of 148 t d-1 (-1σ) and 1,189 t d-1 (+1σ) observed at the NERZ. This study reinforces the importance of performing soil CO2 efflux surveys as an effective surveillance volcanic tool in the NERZ.

  5. Infrared small target enhancement: grey level mapping based on improved sigmoid transformation and saliency histogram

    NASA Astrophysics Data System (ADS)

    Wan, Minjie; Gu, Guohua; Qian, Weixian; Ren, Kan; Chen, Qian

    2018-06-01

    Infrared (IR) small target enhancement plays a significant role in modern infrared search and track (IRST) systems and is the basic technique of target detection and tracking. In this paper, a coarse-to-fine grey level mapping method using improved sigmoid transformation and saliency histogram is designed to enhance IR small targets under different backgrounds. For the stage of rough enhancement, the intensity histogram is modified via an improved sigmoid function so as to narrow the regular intensity range of background as much as possible. For the part of further enhancement, a linear transformation is accomplished based on a saliency histogram constructed by averaging the cumulative saliency values provided by a saliency map. Compared with other typical methods, the presented method can achieve both better visual performances and quantitative evaluations.

  6. Identification and characterisation of local aerosol sources using high temporal resolution measurements.

    PubMed

    Contini, D; Donateo, A; Cesari, D; Belosi, F; Francioso, S

    2010-09-01

    Aerosol and gaseous pollution measurements were carried out at an urban background site in the south of Italy located near an industrial complex. Collection of 24 h samples of PM10 and PM2.5 and successive chemical quantification of metals were performed. Data were compared with measurements taken at a suburban background site, located at 25 km distance. The comparison showed the presence of an industrial contribution with a well defined chemical emission profile, similar, in terms of metals content, to urban emissions. As this made difficult the quantitative characterisation of the contribution of the two sources to atmospheric PM, a statistical method based on the treatment of data arising from high temporal resolution measurements was developed. Data were taken with a micrometeorological station based on an integrating nephelometer (Mie pDR-1200) for optical detection of PM2.5 concentration, with successive evaluation of vertical turbulent fluxes using the eddy-correlation method. Results show that the contribution from the two sources (urban emissions and industrial releases) have a very different behaviour, with the industrial contribution being present at high wind velocity with short concentration peaks (average duration 4 min) associated to strong positive and negative vertical fluxes. The estimated contribution to PM2.5 is 2.3% over long-term averages. The urban emissions are mainly present at low wind velocity, with longer concentration peaks in the morning and late evening hours, generally associated to small positive vertical fluxes. The characterisation of the contribution was performed using deposition velocity V(d) that is on average -3.5 mm s(-1) and has a diurnal pattern, with negligible values during the night and a minimum value of around -9 mm s(-1) late in the afternoon. Results show a correlation between V(d), friction velocity and wind velocity that could be the basis for a parameterisation of V(d) to be used in dispersion codes.

  7. Occurrence and air-soil exchange of organochlorine pesticides and polychlorinated biphenyls at a CAWNET background site in central China: Implications for influencing factors and fate.

    PubMed

    Zhan, Lingxi; Lin, Tian; Wang, Zuwu; Cheng, Zhineng; Zhang, Gan; Lyu, Xiaopu; Cheng, Hairong

    2017-11-01

    Ambient air and soil samples were collected between March 2012 and March 2013 at Jinsha, a regional background site in central China, to measure the concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs). The average concentrations of total OCPs and total PCBs were 191 ± 107 and 39.4 ± 27.1 pg/m 3 in air (gaseous and particulate phase) and 0.585 ± 0.437 and 0.083 ± 0.039 ng/g in soil, respectively. The higher concentrations of p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT) and p,p'-DDT/p,p'-DDE ratios in the soil indicated recent p,p'-DDT input to the soil. A strong positive temperature dependence and average fugacity fraction value > 0.5 were observed for p,p'-DDT, suggesting that volatilization of residual DDT in the soil was the main influencing factor on atmospheric p,p'-DDT. Highly average fugacity fractions (>0.7) of trans-chlordane (TC) and cis-chlordane (CC) and high TC/CC ratios both in the soil and atmosphere suggested fresh inputs. Higher gaseous concentrations of hexachlorobenzene (HCB) were observed in winter and negative temperature dependence was directly attributed to the surrounding ongoing source (e.g. fuel consuming activities), especially in winter. Overall, most targeted OCPs and PCBs were influenced by long-range transport, and fugacity fraction values indicated highly volatile compounds (e.g. α-hexachlorocyclohexane (α-HCH) and lower chlorinated PCBs) were volatilized and low volatility compounds (e.g. p,p'-DDE and higher chlorinated PCBs) were deposited at the air-soil interface. Knowing the source and sink of OCPs and PCBs can help to control their pollution in this area and provide a reference for other studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Fluoride toxicity and bioaccumulation in the invasive amphipod Dikerogammarus villosus (Sowinsky, 1894): a laboratory study.

    PubMed

    Gonzalo, Cristina; Camargo, Julio A; Masiero, Luciano; Casellato, Sandra

    2010-11-01

    The tolerance of the invasive amphipod Dikerogammarus villosus to fluoride (F⁻) toxicity was examined via laboratory experiments. 96-h LC₅₀ and 240-h NOEC values were estimated to be 5.8 and 0.95 mg F⁻/L, respectively. Average whole-body fluoride content in control amphipods was 27.6 μg F⁻/g dry weight, whereas in exposed amphipods it ranged from 3,637 to 16,994 μg F⁻/g dry weight. All these results indicate that D. villosus is a very sensitive species to fluoride toxicity. Overall it is concluded that the potential risk of invasion for D. villosus in either natural or polluted freshwater ecosystems, exhibiting relatively high fluoride levels (at least ten-fold higher than the average freshwater background level of 0.15 mg F⁻/L), must be low.

  9. Atmospheric aerosol and gaseous pollutant concentrations in Bucharest area using first datasets from the city AQ monitoring network

    NASA Astrophysics Data System (ADS)

    Balaceanu, Cristina; Iorga, Gabriela

    2010-05-01

    City of Bucharest is the largest and most populated (about 2.8 million inhabitants) city in the Romanian Plain and encounters environmental problems and meteorology typical for several cities in southeastern Europe. City environment includes intense emissions arising from traffic (about 1 million cars per day), five thermo-electrical power-generation stations, that use both natural gas and oil derivatives for power generation and domestic heating, and from industrial sources (more than 800 small and medium plants). In the present work we performed an extensive analysis of the air pollution state for the Bucharest area (inside and outside the city) using filter measurement aerosol data PM10 and PM2.5. Data spanning over first year of continuous sampling (2005) were taken from the city Air Quality Monitoring Network, which consists of eight sampling stations: three industrial and two traffic, one EPA urban background, one suburban and one regional station located outside of Bucharest. The objective was to assess the PM10 recorded levels and their degree of compliance with the EU-legislated air quality standards and to provide a statistical investigation of the factors controlling seasonal and spatial variations of PM levels. PM10 relationships with other measured air pollutants (SO2, CO, NOx) and meteorological parameters (temperature, relative humidity, atmospheric pressure, wind velocity and direction) were investigated by statistical analysis. Back trajectory modeling and wind direction frequency distributions were used to identify the origin of the polluted air masses. Contribution of combustion (slopes) and non-combustion (intercepts) sources to PM10 recorded levels was quantified by linear analysis, for two seasonal periods: cold (15 October-14 April) and warm (15 April-14 October). PM10 and PM2.5 concentrations were compared with corresponding values in other European urban areas. Main conclusions are as follows: Traffic and industrial sites contribute to the PM10 urban background with about 86%; relative contribution of urban background to regional background is about 37%; Relatively low inter-sites correlation coefficients and no significant geographic differences between sites, more or less uniform traffic pattern suggests local sources may play an important role; PM10average and median values systematically exceed the limit value of 50 ?g/m3 at traffic and industrial sites; at background sites the PM10 are below 50?g/m3 but are higher that values at similar sites in Europe; CO and SO2 do not put serious problems relative to their limits values as NOx does; NOx shows a temporal variation with higher values during the cold season; All gaseous pollutants contribute to the PM10 levels but a significant inter-annual variation of this contribution seems not to be observed; Pollution level in Bucharest seems to be higher than in other European cities for traffic, industrial and suburban background sites; regional background in the larger area of Bucharest seems to be similar with the suburban background sites in other European sites. Seven pollution episodes were identified, from which only one in the cold season has been attributed to the long-range transport. During this episode PM10 levels varied between 161-205 ?g/m3 for all sites, the dominant wind direction was NE (10.2%), with an average wind speed of 1.6 m/s. This shows that local pollution sources seem to have more impact on AQ than the long-range transport. Data presented here give an overview of the range of air pollution concentrations to expect under typical meteorological and seasonal conditions in the larger area of Bucharest. Acknowledgements: Dr. Ing. Danut Cociorva, Leader of the Air Quality Control Group-NIRD-ICIM Bucharest, is gratefully acknowledged for his permission to analyse the data. The air mass back trajectories were calculated using HYSPLIT transport and dispersion model: www.arl.noaa.gov/ ready.html. Financial support from ÖAD Austria, Programm WTZ, Project No: RO 02/2009 and from ANCS Romania, Programm PN II, Contract No: 304/27.04.2009 is gratefully acknowledged.

  10. Economic Valuation of Health Care Services in Public Health Systems: A Study about Willingness to Pay (WTP) for Nursing Consultations

    PubMed Central

    Martín-Fernández, Jesús; del Cura-González, Mª Isabel; Rodríguez-Martínez, Gemma; Ariza-Cardiel, Gloria; Zamora, Javier; Gómez-Gascón, Tomás; Polentinos-Castro, Elena; Pérez-Rivas, Francisco Javier; Domínguez-Bidagor, Julia; Beamud-Lagos, Milagros; Tello-Bernabé, Mª Eugenia; Conde-López, Juan Francisco; Aguado-Arroyo, Óscar; Bayona, Mª Teresa Sanz-; Gil-Lacruz, Ana Isabel

    2013-01-01

    Background Identifying the economic value assigned by users to a particular health service is of principal interest in planning the service. The aim of this study was to evaluate the perception of economic value of nursing consultation in primary care (PC) by its users. Methods and Results Economic study using contingent valuation methodology. A total of 662 users of nursing consultation from 23 health centers were included. Data on demographic and socioeconomic characteristics, health needs, pattern of usage, and satisfaction with provided service were compiled. The validity of the response was evaluated by an explanatory mixed-effects multilevel model in order to assess the factors associated with the response according to the welfare theory. Response reliability was also evaluated. Subjects included in the study indicated an average Willingness to Pay (WTP) of €14.4 (CI 95%: €13.2–15.5; median €10) and an average Willingness to Accept [Compensation] (WTA) of €20.9 (CI 95%: €19.6–22.2; median €20). Average area income, personal income, consultation duration, home visit, and education level correlated with greater WTP. Women and older subjects showed lower WTP. Fixed parameters explained 8.41% of the residual variability, and response clustering in different health centers explained 4–6% of the total variability. The influence of income on WTP was different in each center. The responses for WTP and WTA in a subgroup of subjects were consistent when reassessed after 2 weeks (intraclass correlation coefficients 0.952 and 0.893, respectively). Conclusions The economic value of nursing services provided within PC in a public health system is clearly perceived by its user. The perception of this value is influenced by socioeconomic and demographic characteristics of the subjects and their environment, and by the unique characteristics of the evaluated service. The method of contingent valuation is useful for making explicit this perception of value of health services. PMID:23626858

  11. Seasonal and diurnal variations of ozone at a high-altitude mountain baseline station in East Asia

    NASA Astrophysics Data System (ADS)

    Ou Yang, Chang-Feng; Lin, Neng-Huei; Sheu, Guey-Rong; Lee, Chung-Te; Wang, Jia-Lin

    2012-01-01

    Continuous measurements of tropospheric ozone were conducted at the Lulin Atmospheric Background Station (LABS) at an altitude of 2862 m from April 2006 to the end of 2009. Distinct seasonal variations in the ozone concentration were observed at the LABS, with a springtime maximum and a summertime minimum. Based on a backward trajectory analysis, CO data, and ozonesondes, the springtime maximum was most likely caused by the long-range transport of air masses from Southeast Asia, where biomass burning was intense in spring. In contrast, a greater Pacific influence contributed to the summertime minimum. In addition to seasonal variations, a distinct diurnal pattern was also observed at the LABS, with a daytime minimum and a nighttime maximum. The daytime ozone minimum was presumably caused by sinks of dry deposition and NO titration during the up-slope transport of surface air. The higher nighttime values, however, could be the result of air subsidence at night bringing ozone aloft to the LABS. After filtering out the daytime data to remove possible local surface contributions, the average background ozone value for the period of 2006-2009 was approximately 36.6 ppb, increased from 32.3 ppb prior to data filtering, without any changes in the seasonal pattern. By applying HYSPLIT4 model analysis, the origins of the air masses contributing to the background ozone observed at the LABS were investigated.

  12. The effect of selenium on spoil suitability as root zone material at Navajo Mine, New Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lane, J.R.; Buchanan, B.A.; Ramsey, T.C.

    1995-09-01

    The root zone suitability limits for spoil Se at Navajo Mine in northwest New Mexico are currently 0.8 ppm total Se and 0.15 ppm hot-water soluble Se. These criteria were largely developed by the Office of Surface Mining using data from the Northern Great Plains. Applying these values, approximately 23% of the spoil volume and 47% of the spoil area sampled at Navajo Mine from 1985 to December 1993 were determined to be unsuitable as root zone material. Secondary Se accumulator plants (Atriplex canescens) growing in both undisturbed and reclaimed areas were randomly sampled for selenium from 1985 to Decembermore » 1993. In most cases the undisturbed soil and reclaimed spoil at these plant sampling sites were sampled for both total and hot-water soluble Se. Selenium values for Atriplex canescens samples collected on the undisturbed sites averaged 0.64 ppm and ranged from 0.20 ppm to 2.5 ppm. Selenium values for the plants growing on spoil ranged from 0.02 ppm to 7.75 ppm and averaged 1.07 ppm. Total and hot-water Se values for spoil averaged 0.66 ppm and 0.06 ppm respectively, and ranged from 0.0 to 14.2 for total Se and 0.0 ppm to 0.72 ppm for hot-water soluble Se. The plant Se values were poorly correlated to both total and hot-water soluble Se values for both soil and spoil. Therefore, predicting suitable guidelines using normal regression techniques was ineffective. Based on background Se levels in native soils, and levels found on reclaimed areas with Atriplex canescens, it is suggested that a total Se level of 2.0 ppm and a hot-water soluble Se level of 0.25 ppm should be used to represent the suitability limits for Se at Navajo Mine. If these Se values are used, it is estimated that less than 1% of the spoil volume would be unsuitable. This volume of spoil seems to be a more accurate estimate of the amount of spoil with unsuitable levels of Se than the estimated 23% using the current guidelines.« less

  13. [Effect of the Disease Management Program on HbA1c Value in Type 2 Diabetes Mellitus Patients: A Retrospective Comparison between Disease Management Programs and Standard Care].

    PubMed

    Wiefarn, Stefan; Kostev, Karel; Heumann, Christian; Rettelbach, Anja

    2017-10-01

    Background  This retrospective study aims to measure the effect of the disease management program (DMP) for type 2 diabetes mellitus (T2DM) patients on HbA 1c value within Germany. Methods  This study is based on patient data from the Disease Analyzer panel (IMS Health). An adequate control group was created using 2:1 propensity score matching. After matching, the analysis included 14 759 patients. Of these, 5875 participated in a DMP while 8884 received standard care. The DMP effect was estimated on the basis of the matched data, using an unpaired t-test. In addition, subgroups were considered from the perspective of personalized medicine. Results  The reduction in HbA 1c values in the DMP group amounted to an average of 1.0 percentage point (baseline HbA 1c  = 8.1 vs. final HbA 1c  = 7.1), while the SC group was able to achieve an average reduction in HbA 1c values of 0.9 percentage point (baseline HbA 1c  = 8.1 vs. final HbA 1c  = 7.2). The DMP group thus achieved an average reduction in HbA 1c values that exceeded that of the SC group by only 0.1 percentage point (95 % CI: 0.04 - 0.16). Descriptively, it also became apparent that patients from the DMP group received a greater average number of annual prescriptions and had more HbA 1c measurements. The subgroup analysis identified groups of patients who benefit more from DMPs than others. Thus, young patients or patients who are being treated by diabetologists are able to benefit most from a DMP. Furthermore, the baseline HbA 1c value has an influence on the DMP effect. Conclusion  T2DM patients in the DMP exhibit a significantly higher reduction in HbA 1c value. However, it is questionable whether this effect is clinically relevant. Certain groups of patients benefit more from DMPs than others. Nevertheless, further studies are needed in order to better understand the impact of the DMP on HbA 1c value and the reasons for the subgroup effects. Such studies should be carried out using a randomized controlled design. © Georg Thieme Verlag KG Stuttgart · New York.

  14. Estimation of background radiation doses for the Peninsular Malaysia's population by ESR dosimetry of tooth enamel.

    PubMed

    Rodzi, Mohd; Zhumadilov, Kassym; Ohtaki, Megu; Ivannikov, Alexander; Bhattacharjee, Deborshi; Fukumura, Akifumi; Hoshi, Masaharu

    2011-08-01

    Background radiation dose is used in dosimetry for estimating occupational doses of radiation workers or determining radiation dose of an individual following accidental exposure. In the present study, the absorbed dose and the background radiation level are determined using the electron spin resonance (ESR) method on tooth samples. The effect of using different tooth surfaces and teeth exposed with single medical X-rays on the absorbed dose are also evaluated. A total of 48 molars of position 6-8 were collected from 13 district hospitals in Peninsular Malaysia. Thirty-six teeth had not been exposed to any excessive radiation, and 12 teeth had been directly exposed to a single X-ray dose during medical treatment prior to extraction. There was no significant effect of tooth surfaces and exposure with single X-rays on the measured absorbed dose of an individual. The mean measured absorbed dose of the population is 34 ± 6.2 mGy, with an average tooth enamel age of 39 years. From the slope of a regression line, the estimated annual background dose for Peninsular Malaysia is 0.6 ± 0.3 mGy y(-1). This value is slightly lower than the yearly background dose for Malaysia, and the radiation background dose is established by ESR tooth measurements on samples from India and Russia.

  15. Atmospheric Sb in the Arctic during the past 16,000 years: Responses to climate change and human impacts

    NASA Astrophysics Data System (ADS)

    Krachler, Michael; Zheng, Jiancheng; Fisher, David; Shotyk, William

    2008-03-01

    Applying strict clean room procedures and sector field inductively coupled plasma mass spectrometry (ICP-MS) methods, concentrations of Sb and Sc were determined in 57 sections of a 170.6-m-long ice core drilled on Devon Island, Arctic Canada, in 1999, providing a record of atmospheric Sb extending back 15,800 years. Natural background concentrations of Sb and Sc established during the period between 1300 years BP and 10,590 years BP averaged 0.08 ± 0.03 pg/g (N = 18) and 0.44 ± 0.20 pg/g (N = 17), respectively. Scandium, a conservative reference element, was used as a surrogate for mineral dust inputs. The Sb/Sc ratio of 0.13 ± 0.07 in these ancient ice samples is comparable to the corresponding ratio of 0.09 ± 0.03 in peat samples from Switzerland from circa 6000 to 9000 years BP, indicating that this natural background ratio might have a much broader validity. The natural background flux of Sb (0.7 ± 0.5 ng/m2/a) in the Arctic was approximately 500 times lower than that established in central Europe using peat cores. For comparison with background values, modern Sb fluxes calculated using 45 samples from a 5-m snow pit dug on Devon Island in 2004, reflecting 10 years of snow accumulation, yielded an average deposition rate of 340 ± 270 ng/m2/a (range: 20-1240 ng/m2/a) with pronounced accumulation of Sb during winter periods when air masses reaching the Arctic predominantly come from Eurasia. These data reveal that approximately 99.8% of the Sb deposited in the Arctic today originates from anthropogenic activities. Modern Sb enrichment factors averaged 25 (range: 8-121). The ice core provides evidence of Sb contamination dating from Phoenician/Greek, Roman, and medieval lead mining and smelting in Europe. Moreover, the ice core data indicate that anthropogenic sources of Sb have continuously dominated the atmospheric inputs to the Arctic for at least 700 years.

  16. Estimates of N2O, NO and NH3 Emissions From Croplands in East, Southeast and South Asia

    NASA Astrophysics Data System (ADS)

    Yan, X.; Ohara, T.; Akimoto, H.

    2002-12-01

    Agricultural activities have greatly altered the global nitrogen cycle and produced nitrogenous gases of environmentally significance. More than half of the global chemical nitrogen fertilizer is used for crop production in East, Southeast and South Asia where rice the center of nutrition. Emissions of nitrous oxide (N2O), nitric oxide (NO) and ammonia (NH3) from croplands in this region were estimated by considering both background emission and emissions resulted from nitrogen added to croplands, including chemical nitrogen, animal manure used as fertilizer, biological fixed nitrogen and nitrogen in crop residue returned to field. Background emission fluxes of N2O and NO from croplands were estimated at 1.16 and 0.52 kg N ha-1yr-1, respectively. A fertilizer-induced N2O emission factor of 1.25% for upland was adopted from IPCC guidelines, and a factor of 0.25% was derived for paddy field from measurements. Total N2O emission from croplands in the region was estimated at 1.16 Tg N yr-1, with 41% contributed by background emission which was not considered in previous global estimates. However, the average fertilizer-induced N2O emission is only 0.93%, lower than the default IPCC value of 1.25% due to the low emission factor from paddy field. A fertilizer-induced NO emission factor of 0.66% for upland was derived from field measurements, and a factor of 0.13% was assumed for paddy field. Total NO emission was 572 Gg N yr-1 in the region, with 38% due to background emission. Average fertilizer-induce NO emission factor was 0.48%. Extrapolating this estimate to global scale will result in a global NO emission from cropland of 1.6 Tg N yr-1, smaller than other global estimates. Total NH3 emission was estimated at 11.8 Tg N yr-1. The use of urea and ammonium bicarbonate and the cultivation of rice lead to a high average NH3 loss rate of chemical fertilizer in the region. Emissions were distributed at 0.5° grid by using a global landuse database.

  17. --No Title--

    Science.gov Websites

    2008112500 2008112400 Background information bias reduction = ( | domain-averaged ensemble mean bias | - | domain-averaged bias-corrected ensemble mean bias | / | domain-averaged bias-corrected ensemble mean bias

  18. Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium

    PubMed Central

    Poussaint, Tina Young; Vajapeyam, Sridhar; Ricci, Kelsey I.; Panigrahy, Ashok; Kocak, Mehmet; Kun, Larry E.; Boyett, James M.; Pollack, Ian F.; Fouladi, Maryam

    2016-01-01

    Background Diffuse intrinsic pontine glioma (DIPG) is associated with poor survival regardless of therapy. We used volumetric apparent diffusion coefficient (ADC) histogram metrics to determine associations with progression-free survival (PFS) and overall survival (OS) at baseline and after radiation therapy (RT). Methods Baseline and post-RT quantitative ADC histograms were generated from fluid-attenuated inversion recovery (FLAIR) images and enhancement regions of interest. Metrics assessed included number of peaks (ie, unimodal or bimodal), mean and median ADC, standard deviation, mode, skewness, and kurtosis. Results Based on FLAIR images, the majority of tumors had unimodal peaks with significantly shorter average survival. Pre-RT FLAIR mean, mode, and median values were significantly associated with decreased risk of progression; higher pre-RT ADC values had longer PFS on average. Pre-RT FLAIR skewness and standard deviation were significantly associated with increased risk of progression; higher pre-RT FLAIR skewness and standard deviation had shorter PFS. Nonenhancing tumors at baseline showed higher ADC FLAIR mean values, lower kurtosis, and higher PFS. For enhancing tumors at baseline, bimodal enhancement histograms had much worse PFS and OS than unimodal cases and significantly lower mean peak values. Enhancement in tumors only after RT led to significantly shorter PFS and OS than in patients with baseline or no baseline enhancement. Conclusions ADC histogram metrics in DIPG demonstrate significant correlations between diffusion metrics and survival, with lower diffusion values (increased cellularity), increased skewness, and enhancement associated with shorter survival, requiring future investigations in large DIPG clinical trials. PMID:26487690

  19. Contribution of dust storms to PM10 levels in an urban arid environment.

    PubMed

    Krasnov, Helena; Katra, Itzhak; Koutrakis, Petros; Friger, Michael D

    2014-01-01

    Quantitative information on the contribution of dust storms to atmospheric PM10 (particulate matter with an aerodynamic diameter < or = 10 microm) levels is still lacking, especially in urban environments with close proximity to dust sources. The main objective of this study was to quantify the contribution of dust storms to PM10 concentrations in a desert urban center, the city of Beer-Sheva, Negev, Israel, during the period of 2001-2012. Toward this end, a background value based on the "dust-free" season was used as a threshold value to identify potentially "dust days." Subsequently, the net contribution of dust storms to PM10 was assessed. During the study period, daily PM10 concentrations ranged from 6 to over 2000 microg/m3. In each year, over 10% of the daily concentrations exceeded the calculated threshold (BVt) of 71 microg/m3. An average daily net contribution of dust to PM10 of 122 microg/m3 was calculated for the entire study period based on this background value. Furthermore, a dust storm intensity parameter (Ai) was used to analyze several storms with very high PM10 contributions (hourly averages of 1000-5197 microg/m3). This analysis revealed that the strongest storms occurred mainly in the last 3 yr of the study. Finally, these findings indicate that this arid urban environment experiences high PM10 levels whose origin lies in both local and regional dust events. The findings indicate that over time, the urban arid environment experiences high PM10 levels whose origin lies in local and regional dust events. It was noticed that the strongest storms have occurred mainly in the last 3 yr. It is believed that environmental changes such as global warming and desertification may lead to an increased air pollution and risk exposure to human health.

  20. [Algorithm for taking into account the average annual background of air pollution in the assessment of health risks].

    PubMed

    Fokin, M V

    2013-01-01

    State Budgetary Educational Institution of Higher Professional Education "I.M. Sechenov First Moscow State Medical University" of the Ministry of Health care and Social Development, Moscow, Russian Federation. The assessment of health risks from air pollution with emissions from industrial facilities, without the average annual background of air pollution does not meet sanitary legislation. However Russian Federal Service for Hydrometeorology and Environmental Monitoring issues official certificates for a limited number of areas covered by the observations of the full program on the stationary points. Questions of accounting average background air pollution in the evaluation of health risks from exposure to emissions from industrial facilities are considered.

  1. [The medical autonomy of elderly in Taiwan].

    PubMed

    Chen, Kai-Li; Chen, Ching-Huey

    2014-10-01

    The elderly population is increasing rapidly in Taiwan. With the average life expectancy on the rise, the elderly have become major consumers of healthcare products and services. Factors that influence respect for autonomy, a core value of medical ethics, may be related to family, society, and the medical culture. Especially in patients who are already elderly, aging causes declines in physical, mental and societal capacities. Practicing a respect for patient autonomy is particularly challenging for healthcare professionals in Taiwan due the unique culture background of elderly Taiwanese patients. This article reviews and integrates the literature related to the issue of patient autonomy and elaborates on medical decision-making among elderly patients in Taiwan in the contexts of: the disadvantages faced by the elderly, the background of Chinese culture, and the current medical decision-making environment. A few suggestions are proposed to help preserve the medical-decision-making autonomy of elderly patients in Taiwan.

  2. Heavy Metal Contamination and Ecological Risk Assessment of Swine Manure Irrigated Vegetable Soils in Jiangxi Province, China.

    PubMed

    Wang, Maolan; Liu, Ronghao; Lu, Xiuying; Zhu, Ziyi; Wang, Hailin; Jiang, Lei; Liu, Jingjing; Wu, Zhihua

    2018-05-01

    Heavy metal are often added to animal fodder and accumulate in the soils with swine manure. In this study, heavy metal (Cu, Pb, Cd, Zn, As and Cr) concentrations were determined in agricultural soils irrigated with swine manure in Jiangxi Province, China. Results showed that the average concentrations of Cu, Zn, As and Cr (32.8, 93.7, 21.3 and 75.8 mg/kg, respectively) were higher than the background values, while Pb and Cd (15.2 and 0.090 mg/kg, respectively) were lower than the background values. Contamination factors [Formula: see text] indicated that they were generally moderate for Cu, Zn, As and Cr and generally low for Pb and Cd. The contamination degree (C d ) was calculated to be 7.5-10.0 indicating a moderate degree of contamination. The geoaccumulation index (I geo ) indicated that the soils were unpolluted with Zn, Cd and Pb, while unpolluted to moderately pollute with Cr, Cu and As. The single ecological risk factor [Formula: see text] revealed that the six heavy metals all belonged to low ecological risk. The ecological risk indices suggested that all the sampling sites were at low risk level.

  3. A robust background regression based score estimation algorithm for hyperspectral anomaly detection

    NASA Astrophysics Data System (ADS)

    Zhao, Rui; Du, Bo; Zhang, Liangpei; Zhang, Lefei

    2016-12-01

    Anomaly detection has become a hot topic in the hyperspectral image analysis and processing fields in recent years. The most important issue for hyperspectral anomaly detection is the background estimation and suppression. Unreasonable or non-robust background estimation usually leads to unsatisfactory anomaly detection results. Furthermore, the inherent nonlinearity of hyperspectral images may cover up the intrinsic data structure in the anomaly detection. In order to implement robust background estimation, as well as to explore the intrinsic data structure of the hyperspectral image, we propose a robust background regression based score estimation algorithm (RBRSE) for hyperspectral anomaly detection. The Robust Background Regression (RBR) is actually a label assignment procedure which segments the hyperspectral data into a robust background dataset and a potential anomaly dataset with an intersection boundary. In the RBR, a kernel expansion technique, which explores the nonlinear structure of the hyperspectral data in a reproducing kernel Hilbert space, is utilized to formulate the data as a density feature representation. A minimum squared loss relationship is constructed between the data density feature and the corresponding assigned labels of the hyperspectral data, to formulate the foundation of the regression. Furthermore, a manifold regularization term which explores the manifold smoothness of the hyperspectral data, and a maximization term of the robust background average density, which suppresses the bias caused by the potential anomalies, are jointly appended in the RBR procedure. After this, a paired-dataset based k-nn score estimation method is undertaken on the robust background and potential anomaly datasets, to implement the detection output. The experimental results show that RBRSE achieves superior ROC curves, AUC values, and background-anomaly separation than some of the other state-of-the-art anomaly detection methods, and is easy to implement in practice.

  4. Image quality enhancement in low-light-level ghost imaging using modified compressive sensing method

    NASA Astrophysics Data System (ADS)

    Shi, Xiaohui; Huang, Xianwei; Nan, Suqin; Li, Hengxing; Bai, Yanfeng; Fu, Xiquan

    2018-04-01

    Detector noise has a significantly negative impact on ghost imaging at low light levels, especially for existing recovery algorithm. Based on the characteristics of the additive detector noise, a method named modified compressive sensing ghost imaging is proposed to reduce the background imposed by the randomly distributed detector noise at signal path. Experimental results show that, with an appropriate choice of threshold value, modified compressive sensing ghost imaging algorithm can dramatically enhance the contrast-to-noise ratio of the object reconstruction significantly compared with traditional ghost imaging and compressive sensing ghost imaging methods. The relationship between the contrast-to-noise ratio of the reconstruction image and the intensity ratio (namely, the average signal intensity to average noise intensity ratio) for the three reconstruction algorithms are also discussed. This noise suppression imaging technique will have great applications in remote-sensing and security areas.

  5. Estimating Oxygen Needs for Childhood Pneumonia in Developing Country Health Systems: A New Model for Expecting the Unexpected

    PubMed Central

    Bradley, Beverly D.; Howie, Stephen R. C.; Chan, Timothy C. Y.; Cheng, Yu-Ling

    2014-01-01

    Background Planning for the reliable and cost-effective supply of a health service commodity such as medical oxygen requires an understanding of the dynamic need or ‘demand’ for the commodity over time. In developing country health systems, however, collecting longitudinal clinical data for forecasting purposes is very difficult. Furthermore, approaches to estimating demand for supplies based on annual averages can underestimate demand some of the time by missing temporal variability. Methods A discrete event simulation model was developed to estimate variable demand for a health service commodity using the important example of medical oxygen for childhood pneumonia. The model is based on five key factors affecting oxygen demand: annual pneumonia admission rate, hypoxaemia prevalence, degree of seasonality, treatment duration, and oxygen flow rate. These parameters were varied over a wide range of values to generate simulation results for different settings. Total oxygen volume, peak patient load, and hours spent above average-based demand estimates were computed for both low and high seasons. Findings Oxygen demand estimates based on annual average values of demand factors can often severely underestimate actual demand. For scenarios with high hypoxaemia prevalence and degree of seasonality, demand can exceed average levels up to 68% of the time. Even for typical scenarios, demand may exceed three times the average level for several hours per day. Peak patient load is sensitive to hypoxaemia prevalence, whereas time spent at such peak loads is strongly influenced by degree of seasonality. Conclusion A theoretical study is presented whereby a simulation approach to estimating oxygen demand is used to better capture temporal variability compared to standard average-based approaches. This approach provides better grounds for health service planning, including decision-making around technologies for oxygen delivery. Beyond oxygen, this approach is widely applicable to other areas of resource and technology planning in developing country health systems. PMID:24587089

  6. IRAS Colors of the Pleiades

    NASA Technical Reports Server (NTRS)

    Carey, Sean J.; Shipman, R. F.; Clark, F. O.

    1996-01-01

    We present large scale images of the infrared emission of the region around the Pleiades using the ISSA data product from the IRAS mission. Residual Zodiacal background and a discontinuity in the image due to the scanning strategy of the satellite necessitated special background subtraction methods. The 60/100 color image clearly shows the heating of the ambient interstellar medium by the cluster. The 12/100 and 25/100 images peak on the cluster as expected for exposure of small dust grains to an enhanced UV radiation field; however, the 25/100 color declines to below the average interstellar value at the periphery of the cluster. Potential causes of the color deficit are discussed. A new method of identifying dense molecular material through infrared emission properties is presented. The difference between the 100 micron flux density and the 60 micron flux density scaled by the average interstellar 60/100 color ratio (Delta I(sub 100) is a sensitive diagnostic of material with embedded heating sources (Delta I(sub 100) less than 0) and cold, dense cores (Delta I(sub 100) greater than 0). The dense cores of the Taurus cloud complex as well as Lynds 1457 are clearly identified by this method, while the IR bright but diffuse Pleiades molecular cloud is virtually indistinguishable from the nearby infrared cirrus.

  7. Simulations and phantom evaluations of magnetic resonance electrical impedance tomography (MREIT) for breast cancer detection

    NASA Astrophysics Data System (ADS)

    Sadleir, Rosalind J.; Sajib, Saurav Z. K.; Kim, Hyung Joong; Kwon, Oh In; Woo, Eung Je

    2013-05-01

    MREIT is a new imaging modality that can be used to reconstruct high-resolution conductivity images of the human body. Since conductivity values of cancerous tissues in the breast are significantly higher than those of surrounding normal tissues, breast imaging using MREIT may provide a new noninvasive way of detecting early stage of cancer. In this paper, we present results of experimental and numerical simulation studies of breast MREIT. We built a realistic three-dimensional model of the human breast connected to a simplified model of the chest including the heart and evaluated the ability of MREIT to detect cancerous anomalies in a background material with similar electrical properties to breast tissue. We performed numerical simulations of various scenarios in breast MREIT including assessment of the effects of fat inclusions and effects related to noise levels, such as changing the amplitude of injected currents, effect of added noise and number of averages. Phantom results showed straightforward detection of cancerous anomalies in a background was possible with low currents and few averages. The simulation results showed it should be possible to detect a cancerous anomaly in the breast, while restricting the maximal current density in the heart below published levels for nerve excitation.

  8. MRI-based patient-specific human carotid atherosclerotic vessel material property variations in patients, vessel location and long-term follow up

    PubMed Central

    Wang, Qingyu; Canton, Gador; Guo, Jian; Guo, Xiaoya; Hatsukami, Thomas S.; Billiar, Kristen L.; Yuan, Chun; Wu, Zheyang

    2017-01-01

    Background Image-based computational models are widely used to determine atherosclerotic plaque stress/strain conditions and investigate their association with plaque progression and rupture. However, patient-specific vessel material properties are in general lacking in those models, limiting the accuracy of their stress/strain measurements. A noninvasive approach of combining in vivo 3D multi-contrast and Cine magnetic resonance imaging (MRI) and computational modeling was introduced to quantify patient-specific carotid plaque material properties for potential plaque model improvements. Vessel material property variation in patients, along vessel segment, and between baseline and follow up were investigated. Methods In vivo 3D multi-contrast and Cine MRI carotid plaque data were acquired from 8 patients with follow-up (18 months) with written informed consent obtained. 3D thin-layer models and an established iterative procedure were used to determine parameter values of the Mooney-Rivlin models for the 81slices from 16 plaque samples. Effective Young’s Modulus (YM) values were calculated for comparison and analysis. Results Average Effective Young’s Modulus (YM) and circumferential shrinkage rate (C-Shrink) value of the 81 slices was 411kPa and 5.62%, respectively. Slice YM value varied from 70 kPa (softest) to 1284 kPa (stiffest), a 1734% difference. Average slice YM values by vessel varied from 109 kPa (softest) to 922 kPa (stiffest), a 746% difference. Location-wise, the maximum slice YM variation rate within a vessel was 311% (149 kPa vs. 613 kPa). The average slice YM variation rate for the 16 vessels was 134%. The average variation of YM values for all patients from baseline to follow up was 61.0%. The range of the variation of YM values was [-28.4%, 215%]. For plaque progression study, YM at follow-up showed negative correlation with plaque progression measured by wall thickness increase (WTI) (r = -0.7764, p = 0.0235). Wall thickness at baseline correlated with WTI negatively, with r = -0.5253 (p = 0.1813). Plaque burden at baseline correlated with YM change between baseline and follow-up, with r = 0.5939 (p = 0.1205). Conclusion In vivo carotid vessel material properties have large variations from patient to patient, along the diseased segment within a patient, and with time. The use of patient-specific, location specific and time-specific material properties in plaque models could potentially improve the accuracy of model stress/strain calculations. PMID:28715441

  9. Trace Elements and Biomarker results of the El Pujal section, Organyà Basin, Catalunya, NE Spain, in relation to OAE1a

    NASA Astrophysics Data System (ADS)

    Socorro, J.; Maurrasse, F. J.

    2016-12-01

    The results of a 13.77 m section studied at the El Pujal site integrates RSTEs, TIC, TOC, petrographic, major elements, and biomarkers. The data reveal at least 6 episodes of RSTEs enrichment (ppm) of [V (61), Ni (96), Co (3), U (1.1), Cr (90), Cu (11), Mo (5), Th (4)] at 1.47 m, 3.68 m, 5.82 m, 7.67 m, 9.78 m and 12.2 m, respectively, with the highest values between 4.38 - 6.82 m. Maximum values in ppm range for Fe (10456 - 15918), P (229 - 396), Al (23721 - 40501), Si (64569 - 106869). TOC values follow much the same fluctuating pattern with sharp increases in weight % of 1.42, 1.49. 1.68, 1.26, 1.11, and 1.34, respectively. In contrast, TIC values range between 62.03% - 79.84% with 6 distinct dips below background average (72.28%) in an inverse pattern relative to the previous proxies with values of 72.15%, 72.12%, 62.03%, 67.13%, 67.38%, and 65.33%, respectively. Similarly, density counts of benthic foraminifera and echinoid fragments show fluctuations contrary to those of RSTEs, major elements and TOC. These opposite patterns suggest the presence of at least 6 dysoxic phases in relation to OAE1a. N-alkanes results reveal a bimodal distribution with predominance of autochthonous marine components (≤ nC19) and macrophytes (nC20 - nC25), with some allochthonous land derived input (>nC25), thus indicating a mixed source of OM. Mean terrestrial/aquatic ratios TARs (nC27+nC29+nC31)/(nC15+nC17+nC19) of 0.21 taken as the background level further corroborates a significant input of terrestrial OM. TAR values during the most pronounced dysoxic interval ( 4.38m to 6.82m) show an inverse relationship relative to RSTEs, TOC and major elements, with decreasing values relative to background levels (0.21). This may be attributed to a dilution effect due to the higher input of land derived, biolimiting nutrients (P, Fe) into the basin, fueling primary production and increasing the input of OM from shorter chain n-alkanes (≤ nC19), hence decreasing the TAR values.

  10. An Anatomical Assessment of Branch Abscission and Branch-base Hydraulic Architecture in the Endangered Wollemia nobilis

    PubMed Central

    Burrows, G. E.; Meagher, P. F.; Heady, R. D.

    2007-01-01

    Background and Aims The branch-base xylem structure of the endangered Wollemia nobilis was anatomically investigated. Wollemia nobilis is probably the only extant tree species that produces only first-order branches and where all branches are cleanly abscised. An investigation was carried out to see if these unusual features might influence branch-base xylem structure and water supply to the foliage. Methods The xylem was sectioned at various distances along the branch bases of 6-year-old saplings. Huber values and relative theoretical hydraulic conductivities were calculated for various regions of the branch base. Key Results The most proximal branch base featured a pronounced xylem constriction. The constriction had only 14–31 % (average 21 %) of the cross-sectional area and 20–42 % (average 28 %) of the theoretical hydraulic conductivity of the more distal branch xylem. Wollemia nobilis had extremely low Huber values for a conifer. Conclusions The branch-base xylem constriction would appear to facilitate branch abscission, while the associated Huber values show that W. nobilis supplies a relatively large leaf area through a relatively small diameter ‘pipe’. It is tempting to suggest that the pronounced decline of W. nobilis in the Tertiary is related to its unusual branch-base structure but physiological studies of whole plant conductance are still needed. PMID:17272303

  11. The presence of radioactive materials in soil, sand and sediment samples of Potenga sea beach area, Chittagong, Bangladesh: Geological characteristics and environmental implication

    NASA Astrophysics Data System (ADS)

    Yasmin, Sabina; Barua, Bijoy Sonker; Uddin Khandaker, Mayeen; Kamal, Masud; Abdur Rashid, Md.; Abdul Sani, S. F.; Ahmed, H.; Nikouravan, Bijan; Bradley, D. A.

    2018-03-01

    Accurate quantification of naturally occurring radioactive materials in soil provides information on geological characteristics, possibility of petroleum and mineral exploration, radiation hazards to the dwelling populace etc. Of practical significance, the earth surface media (soil, sand and sediment) collected from the densely populated coastal area of Chittagong city, Bangladesh were analysed using a high purity germanium γ-ray spectrometer with low background radiation environment. The mean activities of 226Ra (238U), 232Th and 40K in the studied materials show higher values than the respective world average of 33, 36 and 474 Bq/kg reported by the UNSCEAR (2000). The deduced mass concentrations of the primordial radionuclides 238U, 232Th and 40K in the investigated samples are corresponding to the granite rocks, crustal minerals and typical rocks respectively. The estimated mean value of 232Th/238U for soil (3.98) and sediment (3.94) are in-line with the continental crustal average concentration of 3.82 for typical rock range reported by the National Council on Radiation Protection and Measurements (NCRP). But the tonalites and more silicic rocks elevate the mean value of 232Th/238U for sand samples amounting to 4.69. This indicates a significant fractionation during weathering or associated with the metasomatic activity in the investigated area of sand collection.

  12. Highly Resolved Sub-Terahertz Vibrational Spectroscopy of Biological Macromolecules and Bacteria Cells

    DTIC Science & Technology

    2016-07-01

    between average background spectrum and chicken egg - white lysozyme protein spectrum...spectroscopic signatures were conducted using human insulin protein and chicken egg -white lysozyme protein. Proteins with different structures...the comparison between the average background THz spectrum (black line in Figure 13) and the chicken egg -white lysozyme THz spectrum (blue line

  13. Pattern and forcing of Northern Hemisphere glacier variations during the last millennium

    NASA Astrophysics Data System (ADS)

    Porter, Stephen C.

    1986-07-01

    Time series depicting mountain glacier fluctuations in the Alps display generally similar patterns over the last two centuries, as do chronologies of glacier variations for the same interval from elsewhere in the Northern Hemisphere. Episodes of glacier advance consistently are associated with intervals of high average volcanic aerosol production, as inferred from acidity variations in a Greenland ice core. Advances occur whenever acidity levels rise sharply from background values to reach concentrations ≥1.2 μequiv H +/kg above background. A phase lag of about 10-15 yr, equivalent to reported response lags of Alpine glacier termini, separates the beginning of acidity increases from the beginning of subsequent ice advances. A similar relationship, but based on limited and less-reliable historical data and on lichenometric ages, is found for the preceding 2 centuries. Calibrated radiocarbon dates related to advances of non-calving and non-surging glaciers during the earlier part of the Little Ice Age display a comparable consistent pattern. An interval of reduced acidity values between about 1090 and 1230 A.D. correlates with a time of inferred glacier contraction during the Medieval Optimum. The observed close relation between Noothern Hemisphere glacier fluctuations and variations in Greenland ice-core acidity suggests that sulfur-rich aerosols generated by volcanic eruptions are a primary forcing mechanism of glacier fluctuations, and therefore of climate, on a decadal scale. The amount of surface cooling attributable to individual large eruptions or to episodes of eruptions is simlar to the probable average temperature reduction during culminations of Little Ice Age alacier advances (ca. 0.5°-1.2°C), as inferred from depression of equilibrium-line altitudes.

  14. Background concentrations and reference values for heavy metals in soils of Cuba.

    PubMed

    Alfaro, Mirelys Rodríguez; Montero, Alfredo; Ugarte, Olegario Muñiz; do Nascimento, Clístenes Williams Araújo; de Aguiar Accioly, Adriana Maria; Biondi, Caroline Miranda; da Silva, Ygor Jacques Agra Bezerra

    2015-01-01

    The potential threat of heavy metals to human health has led to many studies on permissible levels of these elements in soils. The objective of this study was to establish quality reference values (QRVs) for Cd, Pb, Zn, Cu, Ni, Cr, Fe, Mn, As, Hg, V, Ba, Sb, Ag, Co, and Mo in soils of Cuba. Geochemical associations between trace elements and Fe were also studied, aiming to provide an index for establishing background concentrations of metals in soils. Surface samples of 33 soil profiles from areas of native forest or minimal anthropic influence were collected. Samples were digested (USEPA method 3051A), and the metals were determined by ICP-OES. The natural concentrations of metals in soils of Cuba followed the order Fe > Mn > Ni > Cr > Ba > V > Zn > Cu > Pb > Co > As > Sb > Ag > Cd > Mo > Hg. The QRVs found for Cuban soils were as follows (mg kg(-1)): Ag (1), Ba (111), Cd (0.6), Co (25), Cr (153), Cu (83), Fe (54,055), Mn (1947), Ni (170), Pb (50), Sb (6), V (137), Zn (86), Mo (0.1), As (19), and Hg (0.1). The average natural levels of heavy metals are above the global average, especially for Ni and Cr. The chemical fractionation of soil samples presenting anomalous concentrations of metals showed that Cu, Ni, Cr, Sb, and As have low bioavailability. This suggests that the risk of contamination of agricultural products via plant uptake is low. However, the final decision on the establishment of soil QRVs in Cuba depends on political, economic, and social issues and in-depth risk analyses considering all routes of exposure to these elements.

  15. Multiple enface image averaging for enhanced optical coherence tomography angiography imaging.

    PubMed

    Uji, Akihito; Balasubramanian, Siva; Lei, Jianqin; Baghdasaryan, Elmira; Al-Sheikh, Mayss; Borrelli, Enrico; Sadda, SriniVas R

    2018-05-31

    To investigate the effect of multiple enface image averaging on image quality of the optical coherence tomography angiography (OCTA). Twenty-one normal volunteers were enrolled in this study. For each subject, one eye was imaged with 3 × 3 mm scan protocol, and another eye was imaged with the 6 × 6 mm scan protocol centred on the fovea using the ZEISS Angioplex™ spectral-domain OCTA device. Eyes were repeatedly imaged to obtain nine OCTA cube scan sets, and nine superficial capillary plexus (SCP) and deep capillary plexus (DCP) were individually averaged after registration. Eighteen eyes with a 3 × 3 mm scan field and 14 eyes with a 6 × 6 mm scan field were studied. Averaged images showed more continuous vessels and less background noise in both the SCP and the DCP as the number of frames used for averaging increased, with both 3 × 3 and 6 × 6 mm scan protocols. The intensity histogram of the vessels dramatically changed after averaging. Contrast-to-noise ratio (CNR) and subjectively assessed image quality scores also increased as the number of frames used for averaging increased in all image types. However, the additional benefit in quality diminished when averaging more than five frames. Averaging only three frames achieved significant improvement in CNR and the score assigned by certified grades. Use of multiple image averaging in OCTA enface images was found to be both objectively and subjectively effective for enhancing image quality. These findings may of value for developing optimal OCTA imaging protocols for future studies. © 2018 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  16. Effects of fenoterol on ventilatory responses to hypoxia and hypercapnia in normal subjects.

    PubMed Central

    Yoshiike, Y.; Suzuki, S.; Watanuki, Y.; Okubo, T.

    1995-01-01

    BACKGROUND--The effects of beta 2 adrenergic agonists on chemoreceptors remain controversial. This study was designed to examine whether fenoterol, a beta 2 adrenergic agonist, increases the ventilatory responses to hypercapnia (HCVR) and hypoxia (HVR) in normal subjects. METHODS--HCVR was tested with a rebreathing method and HVR was examined with a progressive isocapnic hypoxic method in 11 normal subjects. Both HCVR and HVR were assessed by the slope of occlusion pressure (P0.1) or ventilation (VE) plotted against end tidal carbon dioxide pressure and arterial oxygen saturation, respectively. Respiratory muscle strength, spirometric values and lung volume were measured. After a single oral administration of 5 mg fenoterol or placebo HCVR and HVR were evaluated. RESULTS--Fenoterol treatment did not change the specific airway conductance or forced expiratory volume in one second. Respiratory muscle strength did not change. Fenoterol increased the slope of the HCVR of both P0.1 (from 0.251 (0.116) to 0.386 (0.206) kPa/kPa, average increase 71%) and VE (from 10.7 (3.4) to 15.1 (4.2) l/min/kPa, average increase 52%), and shifted the response curves to higher values. For the HVR fenoterol increased the slopes of both P0.1 and VE (from -4.06 (2.00) x 10(-3) to -7.99 (4.29) x 10(-3) kPa/%, an average increase of 83%, and from -0.221 (0.070) to -0.313 (0.112) l/min/%, a 44.5% increase, respectively), and shifted the response curves to higher values. CONCLUSION--Acute administration of fenoterol increases the ventilatory responses to both hypercapnia and hypoxia in normal subjects. PMID:7701451

  17. Pattern similarity study of functional sites in protein sequences: lysozymes and cystatins

    PubMed Central

    Nakai, Shuryo; Li-Chan, Eunice CY; Dou, Jinglie

    2005-01-01

    Background Although it is generally agreed that topography is more conserved than sequences, proteins sharing the same fold can have different functions, while there are protein families with low sequence similarity. An alternative method for profile analysis of characteristic conserved positions of the motifs within the 3D structures may be needed for functional annotation of protein sequences. Using the approach of quantitative structure-activity relationships (QSAR), we have proposed a new algorithm for postulating functional mechanisms on the basis of pattern similarity and average of property values of side-chains in segments within sequences. This approach was used to search for functional sites of proteins belonging to the lysozyme and cystatin families. Results Hydrophobicity and β-turn propensity of reference segments with 3–7 residues were used for the homology similarity search (HSS) for active sites. Hydrogen bonding was used as the side-chain property for searching the binding sites of lysozymes. The profiles of similarity constants and average values of these parameters as functions of their positions in the sequences could identify both active and substrate binding sites of the lysozyme of Streptomyces coelicolor, which has been reported as a new fold enzyme (Cellosyl). The same approach was successfully applied to cystatins, especially for postulating the mechanisms of amyloidosis of human cystatin C as well as human lysozyme. Conclusion Pattern similarity and average index values of structure-related properties of side chains in short segments of three residues or longer were, for the first time, successfully applied for predicting functional sites in sequences. This new approach may be applicable to studying functional sites in un-annotated proteins, for which complete 3D structures are not yet available. PMID:15904486

  18. Ingestion dose from 238U, 232Th, 226Ra, 40K and 137Cs in cereals, pulses and drinking water to adult population in a high background radiation area, Odisha, India.

    PubMed

    Lenka, Pradyumna; Sahoo, S K; Mohapatra, S; Patra, A C; Dubey, J S; Vidyasagar, D; Tripathi, R M; Puranik, V D

    2013-03-01

    A natural high background radiation area is located in Chhatrapur, Odisha in the eastern part of India. The inhabitants of this area are exposed to external radiation levels higher than the global average background values, due to the presence of uranium, thorium and its decay products in the monazite sands bearing placer deposits in its beaches. The concentrations of (232)Th, (238)U, (226)Ra, (40)K and (137)Cs were determined in cereals (rice and wheat), pulses and drinking water consumed by the population residing around this region and the corresponding annual ingestion dose was calculated. The annual ingestion doses from cereals, pulses and drinking water varied in the range of 109.4-936.8, 10.2-307.5 and 0.5-2.8 µSv y(-1), respectively. The estimated total annual average effective dose due to the ingestion of these radionuclides in cereals, pulses and drinking water was 530 µSv y(-1). The ingestion dose from cereals was the highest mainly due to a high consumption rate. The highest contribution of dose was found to be from (226)Ra for cereals and drinking water and (40)K was the major dose contributor from the intake of pulses. The contribution of man-made radionuclide (137)Cs to the total dose was found to be minimum. (226)Ra was found to be the largest contributor to ingestion dose from all sources.

  19. [Development and Implementation of a Comprehensive Health Management System (Fit for Work and Life) for Employees of a University Hospital - A Practice Report].

    PubMed

    Gutenbrunner, C; Egen, C; Kahl, K G; Briest, J; Tegtbur, U; Miede, J; Born, M

    2017-07-01

    Background: Due to the increase of sick leave, prolonging working life and the prediction of shortage of skilled workers in the future, health management systems are continuously gaining importance. Employees in a University Hospital are exposed to particular stress factors, which are also reflected in a higher than average amount of sick leave. Against this background, the project "Fit for Work and Life" (FWL) was developed and implemented by the Hannover Medical School (MHH). Aims: FWL aims to maintain, improve or recover the work ability of employees by offering both preventive and rehabilitative treatments. A second goal is to significantly reduce the days of sick leave. Methods: The project was jointly developed and implemented by five MHH departments and the DRV Braunschweig-Hannover (DRV BS-H) according to previously defined principles. It was scientifically evaluated by the following outcomes: average days of sick leave, work ability (WAI), quality of life (SF-36, WHOQOL), coping strategies (FERUS) and effort-reward imbalance (ERI). Results and Conclusions: So far, this project is unique in its concept. It has been successfully implemented in the organisational structures of the MHH. 376 employees have registered during the first project year. Up to now, 182 participants have completed their individual programmes. The results show that 60.4% of employees have moderate to poor WAI values. The average of the mental summary scale of the SF-36 was 44.9, indicating a high workload. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Usage of fMRI for pre-surgical planning in brain tumor and vascular lesion patients: Task and statistical threshold effects on language lateralization☆☆☆

    PubMed Central

    Nadkarni, Tanvi N.; Andreoli, Matthew J.; Nair, Veena A.; Yin, Peng; Young, Brittany M.; Kundu, Bornali; Pankratz, Joshua; Radtke, Andrew; Holdsworth, Ryan; Kuo, John S.; Field, Aaron S.; Baskaya, Mustafa K.; Moritz, Chad H.; Meyerand, M. Elizabeth; Prabhakaran, Vivek

    2014-01-01

    Background and purpose Functional magnetic resonance imaging (fMRI) is a non-invasive pre-surgical tool used to assess localization and lateralization of language function in brain tumor and vascular lesion patients in order to guide neurosurgeons as they devise a surgical approach to treat these lesions. We investigated the effect of varying the statistical thresholds as well as the type of language tasks on functional activation patterns and language lateralization. We hypothesized that language lateralization indices (LIs) would be threshold- and task-dependent. Materials and methods Imaging data were collected from brain tumor patients (n = 67, average age 48 years) and vascular lesion patients (n = 25, average age 43 years) who received pre-operative fMRI scanning. Both patient groups performed expressive (antonym and/or letter-word generation) and receptive (tumor patients performed text-reading; vascular lesion patients performed text-listening) language tasks. A control group (n = 25, average age 45 years) performed the letter-word generation task. Results Brain tumor patients showed left-lateralization during the antonym-word generation and text-reading tasks at high threshold values and bilateral activation during the letter-word generation task, irrespective of the threshold values. Vascular lesion patients showed left-lateralization during the antonym and letter-word generation, and text-listening tasks at high threshold values. Conclusion Our results suggest that the type of task and the applied statistical threshold influence LI and that the threshold effects on LI may be task-specific. Thus identifying critical functional regions and computing LIs should be conducted on an individual subject basis, using a continuum of threshold values with different tasks to provide the most accurate information for surgical planning to minimize post-operative language deficits. PMID:25685705

  1. [Acid volatile sulfide and bioaccumulation of Cr in sediments from a municipal polluted river].

    PubMed

    Li, Feng; Wen, Yan-Mao; Zhu, Ping-Ting; Jin, Hui; Song, Wei-Wei; Dai, Rui-Zhi

    2009-03-15

    Samples of sediment, overlying water, pore water, and benthic invertebrate were collected at 13 stations along a typical municipal polluted river in the Pearl River Delta. The samples were analyzed to study relationships between acid volatile sulfide (AVS) versus Cr(III) and Cr(VI) in sediment, overlying water, and pore water as well as Cr in Limnodrilus sp.. Based on the "Cr hypothesis", the relationship between AVS and bioavailability of Cr in heavily polluted areas was explored to extend the utility of AVS measurements as sediment assessments. The mean value of total Cr in sediment was 329.57 mg/kg, which was 9.4 times of background value (35 mg/kg). The result indicated that the study area has been seriously polluted by Cr. The concentrations of Cr(VI) in sediment and overlying water were low, indicating that most of Cr was in the form of Cr(III). In the study area, the value of AVS was relatively high with an average value of 650.38 mg/kg, while Cr in the pore water was low with the average of 68.42 microg/L. Cr(VI) in the pore water was below the detection limit except at Z1 station. The range of Cr concentrations in Limnodrilus sp. was from 12.46 mg/kg to 38.99 mg/kg of dried weight, with the average of 25.85 mg/kg, which was higher than other similar results in the literature. The result showed that the amount of Cr accumulation in Limnodrilus sp. was significant. A further analysis showed a significant correlation between Cr in Limnodrilus sp. and Cr in the pore water (r = 0.614, p < 0.05). Since most of Cr in pore water was in the form of Cr(III), the toxicity of Cr(III) in pore water to organism can not be neglected in the heavily polluted river.

  2. Diagnostic features of quantitative comb-push shear elastography for breast lesion differentiation

    PubMed Central

    Denis, Max; Gregory, Adriana; Mehrmohammadi, Mohammad; Kumar, Viksit; Meixner, Duane; Fazzio, Robert T.; Fatemi, Mostafa

    2017-01-01

    Background Lesion stiffness measured by shear wave elastography has shown to effectively separate benign from malignant breast masses. The aim of this study was to evaluate different aspects of Comb-push Ultrasound Shear Elastography (CUSE) performance in differentiating breast masses. Methods With written signed informed consent, this HIPAA- compliant, IRB approved prospective study included patients from April 2014 through August 2016 with breast masses identified on conventional imaging. Data from 223 patients (19–85 years, mean 59.93±14.96 years) with 227 suspicious breast masses identifiable by ultrasound (mean size 1.83±2.45cm) were analyzed. CUSE was performed on all patients. Three regions of interest (ROI), 3 mm in diameter each, were selected inside the lesion on the B-mode ultrasound which also appeared in the corresponding shear wave map. Lesion elasticity values were measured in terms of the Young’s modulus. In correlation to pathology results, statistical analyses were performed. Results Pathology revealed 108 lesions as malignant and 115 lesions as benign. Additionally, 4 lesions (BI-RADS 2 and 3) were considered benign and were not biopsied. Average lesion stiffness measured by CUSE resulted in 84.26% sensitivity (91 of 108), 89.92% specificity (107 of 119), 85.6% positive predictive value, 89% negative predictive value and 0.91 area under the curve (P<0.0001). Stiffness maps showed spatial continuity such that maximum and average elasticity did not have significantly different results (P > 0.21). Conclusion CUSE was able to distinguish between benign and malignant breast masses with high sensitivity and specificity. Continuity of stiffness maps allowed for choosing multiple quantification ROIs which covered large areas of lesions and resulted in similar diagnostic performance based on average and maximum elasticity. The overall results of this study, highlights the clinical value of CUSE in differentiation of breast masses based on their stiffness. PMID:28257467

  3. Methods in quantitative image analysis.

    PubMed

    Oberholzer, M; Ostreicher, M; Christen, H; Brühlmann, M

    1996-05-01

    The main steps of image analysis are image capturing, image storage (compression), correcting imaging defects (e.g. non-uniform illumination, electronic-noise, glare effect), image enhancement, segmentation of objects in the image and image measurements. Digitisation is made by a camera. The most modern types include a frame-grabber, converting the analog-to-digital signal into digital (numerical) information. The numerical information consists of the grey values describing the brightness of every point within the image, named a pixel. The information is stored in bits. Eight bits are summarised in one byte. Therefore, grey values can have a value between 0 and 256 (2(8)). The human eye seems to be quite content with a display of 5-bit images (corresponding to 64 different grey values). In a digitised image, the pixel grey values can vary within regions that are uniform in the original scene: the image is noisy. The noise is mainly manifested in the background of the image. For an optimal discrimination between different objects or features in an image, uniformity of illumination in the whole image is required. These defects can be minimised by shading correction [subtraction of a background (white) image from the original image, pixel per pixel, or division of the original image by the background image]. The brightness of an image represented by its grey values can be analysed for every single pixel or for a group of pixels. The most frequently used pixel-based image descriptors are optical density, integrated optical density, the histogram of the grey values, mean grey value and entropy. The distribution of the grey values existing within an image is one of the most important characteristics of the image. However, the histogram gives no information about the texture of the image. The simplest way to improve the contrast of an image is to expand the brightness scale by spreading the histogram out to the full available range. Rules for transforming the grey value histogram of an existing image (input image) into a new grey value histogram (output image) are most quickly handled by a look-up table (LUT). The histogram of an image can be influenced by gain, offset and gamma of the camera. Gain defines the voltage range, offset defines the reference voltage and gamma the slope of the regression line between the light intensity and the voltage of the camera. A very important descriptor of neighbourhood relations in an image is the co-occurrence matrix. The distance between the pixels (original pixel and its neighbouring pixel) can influence the various parameters calculated from the co-occurrence matrix. The main goals of image enhancement are elimination of surface roughness in an image (smoothing), correction of defects (e.g. noise), extraction of edges, identification of points, strengthening texture elements and improving contrast. In enhancement, two types of operations can be distinguished: pixel-based (point operations) and neighbourhood-based (matrix operations). The most important pixel-based operations are linear stretching of grey values, application of pre-stored LUTs and histogram equalisation. The neighbourhood-based operations work with so-called filters. These are organising elements with an original or initial point in their centre. Filters can be used to accentuate or to suppress specific structures within the image. Filters can work either in the spatial or in the frequency domain. The method used for analysing alterations of grey value intensities in the frequency domain is the Hartley transform. Filter operations in the spatial domain can be based on averaging or ranking the grey values occurring in the organising element. The most important filters, which are usually applied, are the Gaussian filter and the Laplace filter (both averaging filters), and the median filter, the top hat filter and the range operator (all ranking filters). Segmentation of objects is traditionally based on threshold grey values. (AB

  4. Dose received by occupationally exposed workers at a nuclear medicine department

    NASA Astrophysics Data System (ADS)

    Ávila, O.; Sánchez-Uribe, N. A.; Rodríguez-Laguna, A.; Medina, L. A.; Estrada, E.; Buenfil, A. E.; Brandan, M. E.

    2012-10-01

    Personal Dose Equivalent (PDE) values were determined for occupational exposed workers (OEW) at the Nuclear Medicine Department (NMD) of "Instituto Nacional de Cancerología" (INCan), Mexico, using TLD-100 thermoluminescent dosemeters. OEW at NMD, INCan make use of radiopharmaceuticals for diagnosis and treatment of diseases. Radionuclides associated to a pharmaceutical compound used at this Department are 131I, 18F, 68Ga, 99mTc, 111In and 11C with main gamma emission energies between 140 and 511 keV. Dosemeter calibration was performed at the metrology department of "Instituto Nacional de Investigaciones Nucleares" (ININ), Mexico. Every occupational worker used dark containers with three dosimeters which were replaced monthly for a total of 5 periods. Additionally, control dosemeters were also placed at a site free of radioactive sources in order to determine the background radiation. Results were adjusted to find PDE/day and estimating annual PDE values in the range between 2 mSv (background) and 9 mSv. The mean annual value is 3.51 mSv and the standard deviation SD is 0.78 mSv. Four of the 16 OEW received annual doses higher than the average +1 SD (4.29 mSv). Results depend on OEW daily activities and were consistent for each OEW for the 5 studied periods as well as with PDE values reported by the firm that performs the monthly service. All obtained values are well within the established annual OEW dose limit stated in the "Reglamento General de Seguridad Radiológica", México (50 mSv), as well as within the lower limit recommended by the "International Commission on Radiation Protection" (ICRP), report no.60 (20 mSv). These results verify the adequate compliance of the NMD at INCan, Mexico with the norms given by the national regulatory commission.

  5. A fully automated system for quantification of background parenchymal enhancement in breast DCE-MRI

    NASA Astrophysics Data System (ADS)

    Ufuk Dalmiş, Mehmet; Gubern-Mérida, Albert; Borelli, Cristina; Vreemann, Suzan; Mann, Ritse M.; Karssemeijer, Nico

    2016-03-01

    Background parenchymal enhancement (BPE) observed in breast dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) has been identified as an important biomarker associated with risk for developing breast cancer. In this study, we present a fully automated framework for quantification of BPE. We initially segmented fibroglandular tissue (FGT) of the breasts using an improved version of an existing method. Subsequently, we computed BPEabs (volume of the enhancing tissue), BPErf (BPEabs divided by FGT volume) and BPErb (BPEabs divided by breast volume), using different relative enhancement threshold values between 1% and 100%. To evaluate and compare the previous and improved FGT segmentation methods, we used 20 breast DCE-MRI scans and we computed Dice similarity coefficient (DSC) values with respect to manual segmentations. For evaluation of the BPE quantification, we used a dataset of 95 breast DCE-MRI scans. Two radiologists, in individual reading sessions, visually analyzed the dataset and categorized each breast into minimal, mild, moderate and marked BPE. To measure the correlation between automated BPE values to the radiologists' assessments, we converted these values into ordinal categories and we used Spearman's rho as a measure of correlation. According to our results, the new segmentation method obtained an average DSC of 0.81 0.09, which was significantly higher (p<0.001) compared to the previous method (0.76 0.10). The highest correlation values between automated BPE categories and radiologists' assessments were obtained with the BPErf measurement (r=0.55, r=0.49, p<0.001 for both), while the correlation between the scores given by the two radiologists was 0.82 (p<0.001). The presented framework can be used to systematically investigate the correlation between BPE and risk in large screening cohorts.

  6. An investigation into the vector ellipticity of extremely low frequency magnetic fields from appliances in UK homes

    NASA Astrophysics Data System (ADS)

    Ainsbury, Elizabeth A.; Conein, Emma; Henshaw, Denis L.

    2005-07-01

    Elliptically polarized magnetic fields induce higher currents in the body compared with their plane polarized counterparts. This investigation examines the degree of vector ellipticity of extremely low frequency magnetic fields (ELF-MFs) in the home, with regard to the adverse health effects reportedly associated with ELF-MFs, for instance childhood leukaemia. Tri-axial measurements of the magnitude and phase of the 0-3000 Hz magnetic fields, produced by 226 domestic mains-fed appliances of 32 different types, were carried out in 16 homes in Worcestershire in the summer of 2004. Magnetic field strengths were low, with average (RMS) values of 0.03 ± 0.02 µT across all residences. In contrast, background field ellipticities were high, on average 47 ± 11%. Microwave and electric ovens produced the highest ellipticities: mean respective values of 21 ± 21% and 21 ± 17% were observed 20 cm away from these appliances. There was a negative correlation between field strength and field polarization, which we attribute to the higher relative field contribution close to each individual (single-phase) appliance. The measurements demonstrate that domestic magnetic fields are extremely complex and cannot simply be characterized by traditional measurements such as time-weighted average or peak exposure levels. We conclude that ellipticity should become a relevant metric for future epidemiological studies of health and ELF-MF exposure. This work is supported by the charity CHILDREN with LEUKAEMIA, registered charity number 298405.

  7. Accuracies of genomic breeding values in American Angus beef cattle using K-means clustering for cross-validation

    PubMed Central

    2011-01-01

    Background Genomic selection is a recently developed technology that is beginning to revolutionize animal breeding. The objective of this study was to estimate marker effects to derive prediction equations for direct genomic values for 16 routinely recorded traits of American Angus beef cattle and quantify corresponding accuracies of prediction. Methods Deregressed estimated breeding values were used as observations in a weighted analysis to derive direct genomic values for 3570 sires genotyped using the Illumina BovineSNP50 BeadChip. These bulls were clustered into five groups using K-means clustering on pedigree estimates of additive genetic relationships between animals, with the aim of increasing within-group and decreasing between-group relationships. All five combinations of four groups were used for model training, with cross-validation performed in the group not used in training. Bivariate animal models were used for each trait to estimate the genetic correlation between deregressed estimated breeding values and direct genomic values. Results Accuracies of direct genomic values ranged from 0.22 to 0.69 for the studied traits, with an average of 0.44. Predictions were more accurate when animals within the validation group were more closely related to animals in the training set. When training and validation sets were formed by random allocation, the accuracies of direct genomic values ranged from 0.38 to 0.85, with an average of 0.65, reflecting the greater relationship between animals in training and validation. The accuracies of direct genomic values obtained from training on older animals and validating in younger animals were intermediate to the accuracies obtained from K-means clustering and random clustering for most traits. The genetic correlation between deregressed estimated breeding values and direct genomic values ranged from 0.15 to 0.80 for the traits studied. Conclusions These results suggest that genomic estimates of genetic merit can be produced in beef cattle at a young age but the recurrent inclusion of genotyped sires in retraining analyses will be necessary to routinely produce for the industry the direct genomic values with the highest accuracy. PMID:22122853

  8. Real-Time Airborne Gamma-Ray Background Estimation Using NASVD with MLE and Radiation Transport for Calibration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kulisek, Jonathan A.; Schweppe, John E.; Stave, Sean C.

    2015-06-01

    Helicopter-mounted gamma-ray detectors can provide law enforcement officials the means to quickly and accurately detect, identify, and locate radiological threats over a wide geographical area. The ability to accurately distinguish radiological threat-generated gamma-ray signatures from background gamma radiation in real time is essential in order to realize this potential. This problem is non-trivial, especially in urban environments for which the background may change very rapidly during flight. This exacerbates the challenge of estimating background due to the poor counting statistics inherent in real-time airborne gamma-ray spectroscopy measurements. To address this, we have developed a new technique for real-time estimation ofmore » background gamma radiation from aerial measurements. This method is built upon on the noise-adjusted singular value decomposition (NASVD) technique that was previously developed for estimating the potassium (K), uranium (U), and thorium (T) concentrations in soil post-flight. The method can be calibrated using K, U, and T spectra determined from radiation transport simulations along with basis functions, which may be determined empirically by applying maximum likelihood estimation (MLE) to previously measured airborne gamma-ray spectra. The method was applied to both measured and simulated airborne gamma-ray spectra, with and without man-made radiological source injections. Compared to schemes based on simple averaging, this technique was less sensitive to background contamination from the injected man-made sources and may be particularly useful when the gamma-ray background frequently changes during the course of the flight.« less

  9. Evaluation of Factors Affecting CGMS Calibration

    PubMed Central

    2006-01-01

    Background The optimal number/timing of calibrations entered into the Continuous Glucose Monitoring System (“CGMS”; Medtronic MiniMed, Northridge, CA) have not been previously described. Methods Fifty subjects with T1DM (10–18y) were hospitalized in a clinical research center for ~24h on two separate days. CGMS and OneTouch® Ultra® Meter (“Ultra”; LifeScan, Milpitas, CA) data were obtained. The CGMS was retrospectively recalibrated using the Ultra data varying the number and timing of calibrations. Resulting CGMS values were compared against laboratory reference values. Results There was a modest improvement in accuracy with increasing number of calibrations. The median relative absolute deviation (RAD) was 14%, 15%, 13% and 13% when using 3, 4, 5 and 7 calibration values, respectively (p<0.001). Corresponding percentages of CGMS-reference pairs meeting the ISO criteria were 66%, 67%, 71% and 72% (p<0.001). Nighttime accuracy improved when daytime calibrations (pre-lunch and pre-dinner) were removed leaving only two calibrations at 9p.m. and 6a.m. (median difference: −2 vs. −9mg/dL, p<0.001; median RAD: 12% vs. 15%, p=0.001). Accuracy was better on visits where the average absolute rate of glucose change at the times of calibration was lower. On visits with average absolute rates <0.5, 0.5-<1.0, 1.0-<1.5 and ≥1.5mg/dL/min, median RAD values were 13% vs. 14% vs. 17% vs. 19%, respectively (p=0.05). Conclusions Although accuracy is slightly improved with more calibrations, the timing of the calibrations appears more important. Modifying the algorithm to put less weight on daytime calibrations for nighttime values and calibrating during times of relative glucose stability may have greater impact on accuracy. PMID:16800753

  10. Alcohol consumption and cardiorespiratory fitness in five population-based studies.

    PubMed

    Baumeister, Sebastian E; Finger, Jonas D; Gläser, Sven; Dörr, Marcus; Markus, Marcello Rp; Ewert, Ralf; Felix, Stephan B; Grabe, Hans-Jörgen; Bahls, Martin; Mensink, Gert Bm; Völzke, Henry; Piontek, Katharina; Leitzmann, Michael F

    2018-01-01

    Background Poor cardiorespiratory fitness is a risk factor for cardiovascular morbidity. Alcohol consumption contributes substantially to the burden of disease, but its association with cardiorespiratory fitness is not well described. We examined associations between average alcohol consumption, heavy episodic drinking and cardiorespiratory fitness. Design The design of this study was as a cross-sectional population-based random sample. Methods We analysed data from five independent population-based studies (Study of Health in Pomerania (2008-2012); German Health Interview and Examination Survey (2008-2011); US National Health and Nutrition Examination Survey (NHANES) 1999-2000; NHANES 2001-2002; NHANES 2003-2004) including 7358 men and women aged 20-85 years, free of lung disease or asthma. Cardiorespiratory fitness, quantified by peak oxygen uptake, was assessed using exercise testing. Information regarding average alcohol consumption (ethanol in grams per day (g/d)) and heavy episodic drinking (5+ or 6+ drinks/occasion) was obtained from self-reports. Fractional polynomial regression models were used to determine the best-fitting dose-response relationship. Results Average alcohol consumption displayed an inverted U-type relation with peak oxygen uptake ( p-value<0.0001), after adjustment for age, sex, education, smoking and physical activity. Compared to individuals consuming 10 g/d (moderate consumption), current abstainers and individuals consuming 50 and 60 g/d had significantly lower peak oxygen uptake values (ml/kg/min) (β coefficients = -1.90, β = -0.06, β = -0.31, respectively). Heavy episodic drinking was not associated with peak oxygen uptake. Conclusions Across multiple adult population-based samples, moderate drinkers displayed better fitness than current abstainers and individuals with higher average alcohol consumption.

  11. Impact on dose and image quality of a software-based scatter correction in mammography.

    PubMed

    Monserrat, Teresa; Prieto, Elena; Barbés, Benigno; Pina, Luis; Elizalde, Arlette; Fernández, Belén

    2018-06-01

    Background In 2014, Siemens developed a new software-based scatter correction (Progressive Reconstruction Intelligently Minimizing Exposure [PRIME]), enabling grid-less digital mammography. Purpose To compare doses and image quality between PRIME (grid-less) and standard (with anti-scatter grid) modes. Material and Methods Contrast-to-noise ratio (CNR) was measured for various polymethylmethacrylate (PMMA) thicknesses and dose values provided by the mammograph were recorded. CDMAM phantom images were acquired for various PMMA thicknesses and inverse Image Quality Figure (IQF inv ) was calculated. Values of incident entrance surface air kerma (ESAK) and average glandular dose (AGD) were obtained from the DICOM header for a total of 1088 pairs of clinical cases. Two experienced radiologists compared subjectively the image quality of a total of 149 pairs of clinical cases. Results CNR values were higher and doses were lower in PRIME mode for all thicknesses. IQF inv values in PRIME mode were lower for all thicknesses except for 40 mm of PMMA equivalent, in which IQF inv was slightly greater in PRIME mode. A mean reduction of 10% in ESAK and 12% in AGD in PRIME mode with respect to standard mode was obtained. The clinical image quality in PRIME and standard acquisitions resulted to be similar in most of the cases (84% for the first radiologist and 67% for the second one). Conclusion The use of PRIME software reduces, in average, the dose of radiation to the breast without affecting image quality. This reduction is greater for thinner and denser breasts.

  12. High-precision half-life measurements of the T =1 /2 mirror β decays 17F and 33Cl

    NASA Astrophysics Data System (ADS)

    Grinyer, J.; Grinyer, G. F.; Babo, M.; Bouzomita, H.; Chauveau, P.; Delahaye, P.; Dubois, M.; Frigot, R.; Jardin, P.; Leboucher, C.; Maunoury, L.; Seiffert, C.; Thomas, J. C.; Traykov, E.

    2015-10-01

    Background: Measurements of the f t values for T =1 /2 mirror β+ decays offer a method to test the conserved vector current hypothesis and to determine Vud, the up-down matrix element of the Cabibbo-Kobayashi-Maskawa matrix. In most mirror decays used for these tests, uncertainties in the f t values are dominated by the uncertainties in the half-lives. Purpose: Two precision half-life measurements were performed for the T =1 /2 β+ emitters, 17F and 33Cl, in order to eliminate the half-life as the leading source of uncertainty in their f t values. Method: Half-lives of 17F and 33Cl were determined using β counting of implanted radioactive ion beam samples on a moving tape transport system at the Système de Production d'Ions Radioactifs Accélérés en Ligne low-energy identification station at the Grand Accélérateur National d'Ions Lourds. Results: The 17F half-life result, 64.347 (35) s, precise to ±0.05 % , is a factor of 5 times more precise than the previous world average. The half-life of 33Cl was determined to be 2.5038 (22) s. The current precision of ±0.09 % is nearly 2 times more precise compared to the previous world average. Conclusions: The precision achieved during the present measurements implies that the half-life no longer dominates the uncertainty of the f t values for both T =1 /2 mirror decays 17F and 33Cl.

  13. Detection and correction of laser induced breakdown spectroscopy spectral background based on spline interpolation method

    NASA Astrophysics Data System (ADS)

    Tan, Bing; Huang, Min; Zhu, Qibing; Guo, Ya; Qin, Jianwei

    2017-12-01

    Laser-induced breakdown spectroscopy (LIBS) is an analytical technique that has gained increasing attention because of many applications. The production of continuous background in LIBS is inevitable because of factors associated with laser energy, gate width, time delay, and experimental environment. The continuous background significantly influences the analysis of the spectrum. Researchers have proposed several background correction methods, such as polynomial fitting, Lorenz fitting and model-free methods. However, less of them apply these methods in the field of LIBS Technology, particularly in qualitative and quantitative analyses. This study proposes a method based on spline interpolation for detecting and estimating the continuous background spectrum according to its smooth property characteristic. Experiment on the background correction simulation indicated that, the spline interpolation method acquired the largest signal-to-background ratio (SBR) over polynomial fitting, Lorenz fitting and model-free method after background correction. These background correction methods all acquire larger SBR values than that acquired before background correction (The SBR value before background correction is 10.0992, whereas the SBR values after background correction by spline interpolation, polynomial fitting, Lorentz fitting, and model-free methods are 26.9576, 24.6828, 18.9770, and 25.6273 respectively). After adding random noise with different kinds of signal-to-noise ratio to the spectrum, spline interpolation method acquires large SBR value, whereas polynomial fitting and model-free method obtain low SBR values. All of the background correction methods exhibit improved quantitative results of Cu than those acquired before background correction (The linear correlation coefficient value before background correction is 0.9776. Moreover, the linear correlation coefficient values after background correction using spline interpolation, polynomial fitting, Lorentz fitting, and model-free methods are 0.9998, 0.9915, 0.9895, and 0.9940 respectively). The proposed spline interpolation method exhibits better linear correlation and smaller error in the results of the quantitative analysis of Cu compared with polynomial fitting, Lorentz fitting and model-free methods, The simulation and quantitative experimental results show that the spline interpolation method can effectively detect and correct the continuous background.

  14. --No Title--

    Science.gov Websites

    2008073000 2008072900 2008072800 Background information bias reduction = ( | domain-averaged ensemble mean bias | - | domain-averaged bias-corrected ensemble mean bias | / | domain-averaged bias-corrected ensemble mean bias | NAEFS Products | NAEFS | EMC Ensemble Products EMC | NCEP | National Weather Service

  15. Detecting a Non-Gaussian Stochastic Background of Gravitational Radiation

    NASA Astrophysics Data System (ADS)

    Drasco, Steve; Flanagan, Éanna É.

    2002-12-01

    We derive a detection method for a stochastic background of gravitational waves produced by events where the ratio of the average time between events to the average duration of an event is large. Such a signal would sound something like popcorn popping. Our derivation is based on the somewhat unrealistic assumption that the duration of an event is smaller than the detector time resolution.

  16. High order cell-centered scheme totally based on cell average

    NASA Astrophysics Data System (ADS)

    Liu, Ze-Yu; Cai, Qing-Dong

    2018-05-01

    This work clarifies the concept of cell average by pointing out the differences between cell average and cell centroid value, which are averaged cell-centered value and pointwise cell-centered value, respectively. Interpolation based on cell averages is constructed and high order QUICK-like numerical scheme is designed for such interpolation. A new approach of error analysis is introduced in this work, which is similar to Taylor’s expansion.

  17. Carbonaceous content of atmospheric aerosols in Lisbon urban atmosphere

    NASA Astrophysics Data System (ADS)

    Mirante, Fátima; Oliveira, C.; Martins, N.; Pio, C.; Caseiro, A.; Cerqueira, M.; Alves, C.; Oliveira, C.; Oliveira, J.; Camões, F.; Matos, M.; Silva, H.

    2010-05-01

    Lisbon is the capital city of Portugal with about 565,000 residents and a population density of 6,600 inhabitants per square kilometre. The town is surrounded by satellite cities, forming together a region known as "Lisbon Metropolitan Area" with about 3 million inhabitants. It is estimated that more than one million citizens come into the Lisbon area every day from the outskirts, leading to elevated traffic densities and intense traffic jams. Airborne particulate matter limit values are frequently exceeded, with important consequences on air pollution levels and obvious negative impacts on human health. Atmospheric aerosols are known to have in their structure significant amounts of carbonaceous material. The knowledge of the aerosols carbon content, particularly on their several carbon forms (as TC, EC and OC, meaning respectively Total, Elemental and Organic carbon) is often required to provide information for source attribution. In order to assess the vehicles PM input, two sampling campaigns (summer and winter periods) were carried out in 2008 in Lisbon in two contrasting sites, a roadside and an urban background site. Particulate matter was collected in two fractions on quartz fibre filters using Hi-Vol samplers (coarse fraction, 2.5µm

  18. Occupational exposure to electric fields and induced currents associated with 400 kV substation tasks from different service platforms.

    PubMed

    Korpinen, Leena H; Elovaara, Jarmo A; Kuisti, Harri A

    2011-01-01

    The aim of the study was to investigate the occupational exposure to electric fields, average current densities, and average total contact currents at 400 kV substation tasks from different service platforms (main transformer inspection, maintenance of operating device of disconnector, maintenance of operating device of circuit breaker). The average values are calculated over measured periods (about 2.5 min). In many work tasks, the maximum electric field strengths exceeded the action values proposed in the EU Directive 2004/40/EC, but the average electric fields (0.2-24.5 kV/m) were at least 40% lower than the maximum values. The average current densities were 0.1-2.3 mA/m² and the average total contact currents 2.0-143.2 µA, that is, clearly less than the limit values of the EU Directive. The average values of the currents in head and contact currents were 16-68% lower than the maximum values when we compared the average value from all cases in the same substation. In the future it is important to pay attention to the fact that the action and limit values of the EU Directive differ significantly. It is also important to take into account that generally, the workers' exposure to the electric fields, current densities, and total contact currents are obviously lower if we use the average values from a certain measured time period (e.g., 2.5 min) than in the case where exposure is defined with only the help of the maximum values. © 2010 Wiley-Liss, Inc.

  19. Adolescent Sibling Relationships in Mexican American Families: Exploring the Role of Familism

    PubMed Central

    Updegraff, Kimberly A.; McHale, Susan M.; Whiteman, Shawn D.; Thayer, Shawna M.; Delgado, Melissa Y.

    2008-01-01

    To address a significant gap in the literature on normative processes in minority families, the authors studied adolescents’ sibling relationships in two-parent Mexican American families and explored connections between sibling relationship characteristics and familism. Participants were 246 adolescent Mexican American sibling pairs who participated in (a) home interviews during which adolescents described their sibling relationships and familism values and (b) a series of 7 nightly phone calls during which adolescents reported their daily activities, including time spent with siblings and family members. Siblings described their relationships as both intimate and conflictual, and daily activity data revealed that they spent an average of 17.2 hr per 7 days in shared activities. Sibling relationship qualities were linked to familism values and practices, and stronger patterns of association emerged for sisters than brothers. Discussion highlights the significance of studying the processes that underlie within-group variations among families of different cultural backgrounds. PMID:16402866

  20. Occupational exposure assessment of magnetic fields generated by induction heating equipment-the role of spatial averaging.

    PubMed

    Kos, Bor; Valič, Blaž; Kotnik, Tadej; Gajšek, Peter

    2012-10-07

    Induction heating equipment is a source of strong and nonhomogeneous magnetic fields, which can exceed occupational reference levels. We investigated a case of an induction tempering tunnel furnace. Measurements of the emitted magnetic flux density (B) were performed during its operation and used to validate a numerical model of the furnace. This model was used to compute the values of B and the induced in situ electric field (E) for 15 different body positions relative to the source. For each body position, the computed B values were used to determine their maximum and average values, using six spatial averaging schemes (9-285 averaging points) and two averaging algorithms (arithmetic mean and quadratic mean). Maximum and average B values were compared to the ICNIRP reference level, and E values to the ICNIRP basic restriction. Our results show that in nonhomogeneous fields, the maximum B is an overly conservative predictor of overexposure, as it yields many false positives. The average B yielded fewer false positives, but as the number of averaging points increased, false negatives emerged. The most reliable averaging schemes were obtained for averaging over the torso with quadratic averaging, with no false negatives even for the maximum number of averaging points investigated.

  1. Appraisal of application possibilities of smoothed splines to designation of the average values of terrain curvatures measured after the termination of hard coal exploitation conducted at medium depth

    NASA Astrophysics Data System (ADS)

    Orwat, J.

    2018-01-01

    In paper were presented results of average values calculations of terrain curvatures measured after the termination of subsequent exploitation stages in the 338/2 coal bed located at medium depth. The curvatures were measured on the neighbouring segments of measuring line No. 1 established perpendicularly to the runways of four longwalls No. 001, 002, 005 and 007. The average courses of measured curvatures were designated based on average courses of measured inclinations. In turn, the average values of observed inclinations were calculated on the basis of measured subsidence average values. In turn, they were designated on the way of average-square approximation, which was done by the use of smoothed splines, in reference to the theoretical courses determined by the S. Knothe’s and J. Bialek’s formulas. Here were used standard parameters values of a roof rocks subsidence a, an exploitation rim Aobr and an angle of the main influences range β. The values of standard deviations between the average and measured curvatures σC and the variability coefficients of random scattering of curvatures MC were calculated. They were compared with values appearing in the literature and based on this, a possibility appraisal of the use of smooth splines to designation of average course of observed curvatures of mining area was conducted.

  2. Choice of tip, signal stability, and practical aspects of piezoresponse-force-microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Henrichs, L. F.; Bennett, J.; Bell, A. J.

    2015-08-15

    Piezoresponse force-microscopy (PFM) has become the standard tool to investigate ferroelectrics on the micro- and nanoscale. However, reliability of PFM signals is often problematic and their quantification is challenging and thus not widely applied. Here, we present a study of the reproducibility of PFM signals and of the so-called PFM background signal which has been reported in the literature. We find that PFM signals are generally reproducible to certain extents. The PFM signal difference between 180° domains on periodically poled lithium niobate (PPLN) is taken as the reference signal in a large number of measurements, carried out in a lowmore » frequency regime (30-70 kHz). We show that in comparison to Pt coated tips, diamond coated tips exhibit improved signal stability, lower background signal, and less imaging artifacts related to PFM which is reflected in the spread of measurements. This is attributed to the improved mechanical stability of the conductive layer. The average deviation of the mean PFM signal is 38.3%, for a diamond coated tip. Although this deviation is relatively high, it is far better than values from the literature which showed a deviation of approx. 73.1%. Additionally, we find that the average deviation of the background signal from 0 is 11.6% of the PPLN domain contrast. Thus, the background signal needs to be taken into account when quantifying PFM signals and should be subtracted from PFM signals. Those results are important for quantification of PFM signals, since PPLN might be used for this purpose when PFM signals measured on PPLN are related to its macroscopic d{sub 33} coefficient. Finally, the crucial influence of sample polishing on PFM signals is shown and we recommend to use a multistep polishing route with a final step involving 200 nm sized colloidal silica particles.« less

  3. Assessment of Heavy and Trace Metals in Surface Soil Nearby an Oil Refinery, Saudi Arabia, Using Geoaccumulation and Pollution Indices.

    PubMed

    Alshahri, Fatimh; El-Taher, A

    2018-04-30

    The present study deals with the measurement of heavy and trace metals in the soils of Ras Tanura city nearby one of the oldest and largest oil refineries located on Arabian Gulf, eastern Saudi Arabia. Metals were analyzed in 34 surface soil samples using plasma atomic emission spectrometer (ICPE-9820). The result showed that the mean values of the metals concentrations were in the order: Cd > Mo > Tb > Ce > Hf > Eu > Yb > U > Sm > Rb > Cr > Ni > Pb > Sc > Cs > Zn > Lu > Co. The mean values of Cd (39.9 mg/kg), Mo (13.2 mg/kg), Eu (4.01 mg/kg), Hf (6.09 mg/kg), Tb (8.23 mg/kg), and Yb (3.88) in soil samples were higher than the background values in soil and the world average. The obtained results indicated to elevated levels of Cd and Mo in most samples, with mean concentrations exceeded the background levels by 113 times for Cd and 5 times for Mo. Pollution index (PI) and Geoaccumulation (I geo ) for each metal were calculated to assess the metal contamination level of surface soil in the study area. The assessment results of PI and I geo revealed a significant pollution by Cd, Mo, Eu, Hf, Tb, and Yb in most of sampling sites nearby Ras Tanura refinery.

  4. Novel technique for MR elastography of the prostate using a modified standard endorectal coil as actuator.

    PubMed

    Thörmer, Gregor; Reiss-Zimmermann, Martin; Otto, Josephin; Hoffmann, Karl-Titus; Moche, Michael; Garnov, Nikita; Kahn, Thomas; Busse, Harald

    2013-06-01

    To present a novel method for MR elastography (MRE) of the prostate at 3 Tesla using a modified endorectal imaging coil. A commercial endorectal coil was modified to dynamically generate mechanical stress (contraction and dilation) in a prostate phantom with embedded phantom "lesions" (6 mm diameter) and in a porcine model. Resulting tissue displacements were measured with a motion-sensitive EPI sequence at actuation frequencies of 50-200 Hz. Maps of shear modulus G were calculated from the measured phase-difference shear-wave patterns. In the G maps of the phantom, "lesions" were easily discernible against the background. The average G values of regions of interest placed in the "lesion" (8.2 ± 1.9 kPa) were much higher than those in the background (3.6 ± 1.4 kPa) but systematically lower than values reported by the vendor (13.0 ± 1.0 and 6.7 ± 0.7 kPa, respectively). In the porcine model, shear waves could be generated and measured shear moduli were substantially different for muscle (7.1 ± 2.0 kPa), prostate (3.0 ± 1.4 kPa), and bulbourethral gland (5.6 ± 1.9 kPa). An endorectal MRE concept is technically feasible. The presented technique will allow for simultaneous MRE and MRI acquisitions using a commercial base device with minor, MR-conditional modifications. The diagnostic value needs to be determined in further trials. Copyright © 2012 Wiley Periodicals, Inc.

  5. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.

    PubMed

    Penco, Silvana; Buscema, Massimo; Patrosso, Maria Cristina; Marocchi, Alessandro; Grossi, Enzo

    2008-05-30

    Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifactorial disease in which complex interactions between environmental and genetic susceptibility factors take place. The purpose of this study was to approach genetic data with an innovative statistical method such as artificial neural networks to identify a possible genetic background predisposing to the disease. A DNA multiarray panel was applied to genotype more than 60 polymorphisms within 35 genes selected from pathways of lipid and homocysteine metabolism, regulation of blood pressure, coagulation, inflammation, cellular adhesion and matrix integrity, in 54 sporadic ALS patients and 208 controls. Advanced intelligent systems based on novel coupling of artificial neural networks and evolutionary algorithms have been applied. The results obtained have been compared with those derived from the use of standard neural networks and classical statistical analysis Advanced intelligent systems based on novel coupling of artificial neural networks and evolutionary algorithms have been applied. The results obtained have been compared with those derived from the use of standard neural networks and classical statistical analysis. An unexpected discovery of a strong genetic background in sporadic ALS using a DNA multiarray panel and analytical processing of the data with advanced artificial neural networks was found. The predictive accuracy obtained with Linear Discriminant Analysis and Standard Artificial Neural Networks ranged from 70% to 79% (average 75.31%) and from 69.1 to 86.2% (average 76.6%) respectively. The corresponding value obtained with Advanced Intelligent Systems reached an average of 96.0% (range 94.4 to 97.6%). This latter approach allowed the identification of seven genetic variants essential to differentiate cases from controls: apolipoprotein E arg158cys; hepatic lipase -480 C/T; endothelial nitric oxide synthase 690 C/T and glu298asp; vitamin K-dependent coagulation factor seven arg353glu, glycoprotein Ia/IIa 873 G/A and E-selectin ser128arg. This study provides an alternative and reliable method to approach complex diseases. Indeed, the application of a novel artificial intelligence-based method offers a new insight into genetic markers of sporadic ALS pointing out the existence of a strong genetic background.

  6. [APHAB scores for individual assessment of the benefit of hearing aid fitting].

    PubMed

    Löhler, J; Wollenberg, B; Schönweiler, R

    2017-11-01

    The Abbreviated Profile of Hearing Aid Benefit (APHAB) questionnaire measures subjective hearing impairment on four different subscales pertaining to different listening situations. Using a very large patient cohort, this study aims to show how answers are distributed within the four subscales before and after hearing aid fitting, and what benefit the patients experience. The results are discussed on the basis of the available literature. Between April 2013 and March 2016, 35,000 APHAB questionnaires from nine German statutory health insurance providers were evaluated. The average values before and after hearing aid fitting, as well as the benefit, were determined for all four APHAB subscales and analyzed graphically. The results of the subjective evaluation of hearing impairment before and after hearing aid fitting and the resultant benefit were plotted by percentile distribution graphs and boxplots. The data were analyzed statistically. There was no overlap of the interquartile ranges before and after hearing aid fitting in any of the APHAB subscales. In three scales (EC, BN and RV), the median improvement after hearing aid fitting was nearly 30 percentage points. In the AV subscale, this value was slightly negative. The percentile distribution graphs used in this study allow individual evaluation of subjective hearing impairment before and after hearing aid fitting, as well as of the resultant benefit, on the background of a huge database. Additionally, it is demonstrated why presentation as boxplots and the average benefit values calculated from these is problematic.

  7. Estimates of the occupational exposure to tenorm in the phosphoric acid production plant in Iran.

    PubMed

    Fathabadi, N; Vasheghani Farahani, M; Moradi, M; Hadadi, B

    2012-09-01

    Phosphate rock is used world wide for manufacturing phosphoric acid and several chemical fertilisers. It is known that the phosphate rock contains various concentrations of uranium, thorium, radium and their daughters. The subject of this study is the evaluation of the radiation exposure to workers in the phosphoric acid production plant due to technologically enhanced naturally occurring radioactive materials that can result from the presence of naturally occurring radioactive materials in phosphate ores used in the manufacturing of phosphoric acid. Radiation exposure due to direct gamma radiation, dust inhalation and radon gas has been investigated and external and internal doses of exposed workers have been calculated. Natural radioactivity due to (40)K, (226)Ra and (232)Th have been measured in phosphate rock, phosphogypsum, chemical fertilisers and other samples by gamma spectrometry system with a high-purity germanium. The average concentrations of (226)Ra and (40)K observed in the phosphate rock are 760 and 80 Bq kg(-1), respectively. Annual effective dose from external radiation had a mean value of ∼0.673 mSv y(-1). Dust sampling revealed greatest values in the storage area. The annual average effective dose from inhalation of long-lived airborne was 0.113 mSv y(-1). Radon gas concentrations in the processing plant and storage area were found to be of the same value as the background. In this study the estimated annual effective doses to workers were below 1 mSv y(-1).

  8. A singular-value method for reconstruction of nonradial and lossy objects.

    PubMed

    Jiang, Wei; Astheimer, Jeffrey; Waag, Robert

    2012-03-01

    Efficient inverse scattering algorithms for nonradial lossy objects are presented using singular-value decomposition to form reduced-rank representations of the scattering operator. These algorithms extend eigenfunction methods that are not applicable to nonradial lossy scattering objects because the scattering operators for these objects do not have orthonormal eigenfunction decompositions. A method of local reconstruction by segregation of scattering contributions from different local regions is also presented. Scattering from each region is isolated by forming a reduced-rank representation of the scattering operator that has domain and range spaces comprised of far-field patterns with retransmitted fields that focus on the local region. Methods for the estimation of the boundary, average sound speed, and average attenuation slope of the scattering object are also given. These methods yielded approximations of scattering objects that were sufficiently accurate to allow residual variations to be reconstructed in a single iteration. Calculated scattering from a lossy elliptical object with a random background, internal features, and white noise is used to evaluate the proposed methods. Local reconstruction yielded images with spatial resolution that is finer than a half wavelength of the center frequency and reproduces sound speed and attenuation slope with relative root-mean-square errors of 1.09% and 11.45%, respectively.

  9. [Equivalent continuous noise level in neonatal intensive care unit associated to burnout syndrome].

    PubMed

    Garrido Galindo, A P; Camargo Caicedo, Y; Vélez-Pereira, A M

    2015-01-01

    Noise levels in neonatal intensive care units allow the appearance of symptoms associated with burnout such as stress, irritability, fatigue and emotional instability on health care personnel. The aim of this study was to evaluate the equivalent continuous noise levels in the neonatal intensive care unit and compare the results with noise levels associated with the occurrence of burnout syndrome on the care team. Continuous sampling was conducted for 20 days using a type I sound level meter on the unit. The maximum, the ninetieth percentile and the equivalent continuous noise level (Leq) values were recorded. Noise level is reported in the range of 51.4-77.6 decibels A (dBA) with an average of 64 dBA, 100.6 dBA maximum, and average background noise from 57.9 dBA. Noise levels exceed the standards suggested for neonatal intensive care units, are close to maximum values referred for noise exposure in the occupational standards and to noise levels associated with the onset of burnout; thus allowing to infer the probability of occurrence of high levels of noise present in the unit on the development of burnout in caregivers. Copyright © 2013 Elsevier España, S.L.U. y SEEIUC. All rights reserved.

  10. Enrichment and geo-accumulation of heavy metals and risk assessment of sediments of the Kurang Nallah--feeding tributary of the Rawal Lake Reservoir, Pakistan.

    PubMed

    Zahra, Azmat; Hashmi, Muhammad Zaffar; Malik, Riffat Naseem; Ahmed, Zulkifl

    2014-02-01

    Heavy metal concentrations in sediments of the Kurang stream: a principal feeding tributary of the Rawal Lake Reservoir were investigated using enrichment factor (EF), geoaccumulation index (Igeo) and metal pollution index (MPI) to determine metal accumulation, distribution and its pollution status. Sediment samples were collected from twenty one sites during two year monitoring in pre- and post-monsoon seasons (2007-2008). Heavy metal toxicity risk was assessed using Sediment Quality Guidelines (SQGs), effect range low/effect range median values (ERL/ERM), and threshold effect level/probable effect level (TEL/PEL). Greater mean concentrations of Ni, Mn and Pb were recorded in post-monsoon season whereas metal accumulation pattern in pre-monsoon season followed the order: Zn>Mn>Ni>Cr>Co>Cd>Pb>Cu>Li. Enrichment factor (EF) and geoaccumulation (Igeo) values showed that sediments were loaded with Cd, Zn, Ni and Mn. Comparison with uncontaminated background values showed higher concentrations of Cd, Zn and Ni than respective average shale values. Concentrations of Ni and Zn were above ERL values; however, Ni concentration exceeded the ERM values. Sediment contamination was attributed to anthropogenic and natural processes. The results can be used for effective management of fresh water hilly streams of Pakistan. © 2013.

  11. Characterizing the vertical presence of atmospheric black carbon in the in the high Arctic region from airborne measurements

    NASA Astrophysics Data System (ADS)

    Schulz, H.; Zanatta, M.; Stefanie, W.; Herber, A. B.

    2016-12-01

    Black carbon (BC) is an important contributor to climate change in the Arctic region. Due to its light absorption behavior, BC leads to a direct warming of the corresponding aerosol layer. Nevertheless, the net Arctic warming induced by BC strongly depends on its vertical distribution. At present, the low level of knowledge in BC vertical variability in the Arctic region may introduce a strong source of uncertainty in radiative forcing estimations. Vertical distribution of refractory black carbon (rBC) was investigated in spring 2015 during an aircraft campaign, as part of the NETCARE (Network on Climate and Aerosols: Addressing Key Uncertainties in Remote Canadian Environments) project. A single particle soot photometer was deployed on the research aircraft POLAR-6 during nine flights over the European and Canadian high Arctic. In the European Arctic, a decreasing vertical trend of rBC mass concentration was observed, with an average of 40 ng m-3 below 1000 m asl, and less than 10 ng m-3 above 3000 m asl. Combining potential temperature trends and number fraction of rBC particles, plume events were isolated from background conditions. At the Canadian site of Alert, low and high altitude background conditions were characterized by an average rBC number fraction below 10%, while higher values (17%) were observed during plume events. rBC mass concentration was found to decrease by a factor of five from low altitude background (27 ng m-3) to high altitude background (5.4 ng m-3). The plume event, located between 2500 and 3000 m asl, represented a discontinuity point in the decreasing vertical trend showing a rBC concentration of 25 ng m-3. Moreover, background conditions were characterized by a rBC mass mean diameter of 230 nm, while during plume events the observed mean size distribution was peaking at 180 nm only. Our work provides new insights on vertical variability of rBC properties and plume outbreaks in the high Arctic. This information is of actual interest for decreasing the high uncertainty of radiative forcing and atmospheric warming estimations in the Arctic region.

  12. Contrast-enhanced spectral mammography (CESM) versus breast magnetic resonance imaging (MRI): A retrospective comparison in 66 breast lesions.

    PubMed

    Li, L; Roth, R; Germaine, P; Ren, S; Lee, M; Hunter, K; Tinney, E; Liao, L

    2017-02-01

    The purpose of this study was to retrospectively compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) with that of breast magnetic resonance imaging (BMRI) in breast cancer detection using parameters, including sensitivity, positive predictive value (PPV), lesion size, morphology, lesion and background enhancement, and examination time. A total of 48 women (mean age, 56years±10.6 [SD]) with breast lesions detected between October 2012 and March 2014 were included. Both CESM and BMRI were performed for each patient within 30 days. The enhancement intensity of lesions and breast background parenchyma was subjectively assessed for both modalities and was quantified for comparison. Statistical significance was analyzed using paired t-test for mean size of index lesions in all malignant breasts (an index lesion defined as the largest lesion in each breast), and a mean score of enhancement intensity for index lesions and breast background. PPV, sensitivity, and accuracy were calculated for both CESM and BMRI. The average duration time of CESM and MRI examinations was also compared. A total of 66 lesions were identified, including 62 malignant and 4 benign lesions. Both CESM and BMRI demonstrated a sensitivity of 100% for detection of breast cancer. There was no statistically significant difference between the mean size of index lesions (P=0.108). The enhancement intensity of breast background was significantly lower for CESM than for BMRI (P<0.01). The mean score of enhancement intensity of index lesions on CESM was significantly less than that for BMRI (P<0.01). The smallest lesion that was detected by both modalities measured 4mm. CESM had a higher PPV than BMRI (P>0.05). The average examination time for CESM was significantly shorter than that of BMRI (P<0.01). CESM has similar sensitivity than BMRI in breast cancer detection, with higher PPV and less background enhancement. CESM is associate with significantly shorter exam time thus a more accessible alternative to BMRI, and has the potential to play an important tool in breast cancer detection and staging. Copyright © 2016 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  13. Effect of Energy Equalization on the Intelligibility of Speech in Fluctuating Background Interference for Listeners With Hearing Impairment

    PubMed Central

    D’Aquila, Laura A.; Desloge, Joseph G.; Braida, Louis D.

    2017-01-01

    The masking release (MR; i.e., better speech recognition in fluctuating compared with continuous noise backgrounds) that is evident for listeners with normal hearing (NH) is generally reduced or absent for listeners with sensorineural hearing impairment (HI). In this study, a real-time signal-processing technique was developed to improve MR in listeners with HI and offer insight into the mechanisms influencing the size of MR. This technique compares short-term and long-term estimates of energy, increases the level of short-term segments whose energy is below the average energy, and normalizes the overall energy of the processed signal to be equivalent to that of the original long-term estimate. This signal-processing algorithm was used to create two types of energy-equalized (EEQ) signals: EEQ1, which operated on the wideband speech plus noise signal, and EEQ4, which operated independently on each of four bands with equal logarithmic width. Consonant identification was tested in backgrounds of continuous and various types of fluctuating speech-shaped Gaussian noise including those with both regularly and irregularly spaced temporal fluctuations. Listeners with HI achieved similar scores for EEQ and the original (unprocessed) stimuli in continuous-noise backgrounds, while superior performance was obtained for the EEQ signals in fluctuating background noises that had regular temporal gaps but not for those with irregularly spaced fluctuations. Thus, in noise backgrounds with regularly spaced temporal fluctuations, the energy-normalized signals led to larger values of MR and higher intelligibility than obtained with unprocessed signals. PMID:28602128

  14. Direct Medical Costs of Dengue Fever in Vietnam: A Retrospective Study in a Tertiary Hospital

    PubMed Central

    VO, Nhung Thi Tuyet; PHAN, Trang Ngo Diem; VO, Trung Quang

    2017-01-01

    Background In Vietnam, dengue fever is a major health concern, yet comprehensive information on its economic costs is lacking. The present study investigated treatment costs associated with dengue fever from the perspective of health care provision. Methods This retrospective study was conducted between January 2013 and December 2015 in Cu Chi General Hospital. The following dengue-related treatment costs were calculated: hospitalisation, diagnosis, specialised services, drug usage and medical supplies. Average cost per case and treatment cost across different age was calculated. Results In the study period, 1672 patients with dengue fever were hospitalised. The average age was 24.98 (SD = 14.10) years, and 47.5% were males (795 patients). Across age groups, the average cost per episode was USD 48.10 (SD = 3.22). The highest costs (USD 56.61, SD = 48.84) were incurred in the adult age group (> 15 years), and the lowest costs (USD 30.10, SD = 17.27) were incurred in the paediatric age group (< 15 years). Conclusion The direct medical costs of dengue-related hospitalisation place a severe economic burden on patients and their families. The probable economic value of dengue management in Vietnam is significant. PMID:28814934

  15. Noise levels in primary schools of medium sized city in Greece.

    PubMed

    Sarantopoulos, George; Lykoudis, Spyros; Kassomenos, Pavlos

    2014-06-01

    This study presents and evaluates noise levels recorded at 15 school complexes in order to describe the indoor as well as the outdoor acoustic environment of schools and gain insight on controlling factors. Noise levels at the roadside in front of the school, the schoolyard, and 41 classrooms, both occupied and unoccupied, were simultaneously and continuously recorded through the course of a daily timetable (08:20-13:10). The average speech noise level of teachers was separately measured for 1min periods. Indoor noise levels, in all cases, were much higher than internationally recommended values: LAeq,5min averaged 69.0dB in occupied classrooms, and 47.1dB in unoccupied ones. Average speech-to-noise ratio (SNR) was estimated to be 12.0dB(A) during teaching, whereas both indoor and outdoor noise levels were significantly elevated during break time and outdoor physical-educational activities. Corresponding measurements of indoor and outdoor noise suggest that noise from the outside (road and schoolyard) affects the background noise level in the classrooms, however in varying degrees, depending on the specific layout and road traffic characteristics. Using double glazing diminishes this effect. © 2013.

  16. The option value of innovative treatments in the context of chronic myeloid leukemia.

    PubMed

    Sanchez, Yuri; Penrod, John R; Qiu, Xiaoli Lily; Romley, John; Thornton Snider, Julia; Philipson, Tomas

    2012-11-01

    To quantify in the context of chronic myeloid leukemia (CML) the additional value patients receive when innovative treatments enable them to survive until the advent of even more effective future treatments (ie, the "option value"). Observational study using data from the Surveillance, Epidemiology and End Results (SEER) cancer registry comprising all US patients with CML diagnosed between 2000 and 2008 (N = 9,760). We quantified the option value of recent breakthroughs in CML treatment by first conducting retrospective survival analyses on SEER data to assess the effectiveness of TKI treatments, and then forecasting survival from CML and other causes to measure expected future medical progress. We then developed an analytical framework to calculate option value of innovative CML therapies, and used an economic model to value these gains. We calculated the option value created both by future innovations in CML treatment and by medical progress in reducing background mortality. For a recently diagnosed CML patient, the option value of innovative therapies from future medical innovation amounts to 0.76 life-years. This option value is worth $63,000, equivalent to 9% of the average survival gains from existing treatments. Future innovations in CML treatment jointly account for 96% of this benefit. The option value of innovative treatments has significance in the context of CML and, more broadly, in disease areas with rapid innovation. Incorporating option value into traditional valuations of medical innovations is both a feasible and a necessary practice in health technology assessment.

  17. Evaluation of the impact of observations on blended sea surface winds in a two-dimensional variational scheme using degrees of freedom

    NASA Astrophysics Data System (ADS)

    Wang, Ting; Xiang, Jie; Fei, Jianfang; Wang, Yi; Liu, Chunxia; Li, Yuanxiang

    2017-12-01

    This paper presents an evaluation of the observational impacts on blended sea surface winds from a two-dimensional variational data assimilation (2D-Var) scheme. We begin by briefly introducing the analysis sensitivity with respect to observations in variational data assimilation systems and its relationship with the degrees of freedom for signal (DFS), and then the DFS concept is applied to the 2D-Var sea surface wind blending scheme. Two methods, a priori and a posteriori, are used to estimate the DFS of the zonal ( u) and meridional ( v) components of winds in the 2D-Var blending scheme. The a posteriori method can obtain almost the same results as the a priori method. Because only by-products of the blending scheme are used for the a posteriori method, the computation time is reduced significantly. The magnitude of the DFS is critically related to the observational and background error statistics. Changing the observational and background error variances can affect the DFS value. Because the observation error variances are assumed to be uniform, the observational influence at each observational location is related to the background error variance, and the observations located at the place where there are larger background error variances have larger influences. The average observational influence of u and v with respect to the analysis is about 40%, implying that the background influence with respect to the analysis is about 60%.

  18. Measurement of respiratory acoustical signals. Comparison of sensors.

    PubMed

    Pasterkamp, H; Kraman, S S; DeFrain, P D; Wodicka, G R

    1993-11-01

    We assessed the performance of three air-coupled and four contact sensors under standardized conditions of lung sound recording. Recordings were obtained from three of the investigators at the best site on the posterior lower chest as determined by auscultation. Lung sounds were band-pass filtered between 100 and 2,000 Hz and sampled simultaneously with calibrated airflow at a rate of 10 kHz. Fourier techniques were used for power spectral analysis. Average spectra for inspiratory sounds at flows of 2 +/- 0.5 L/s were referenced against background noise at zero flow. Air-coupled and contact sensors had comparable maximum signal-to-noise ratios and gave similar values for most spectral parameters. Unexpectedly, less sensitivity (lower signal-to-noise ratio) at high frequencies was observed in the air-coupled devices. Sensor performance needs to be characterized in studies of lung sounds. We suggest that lung sound spectra should be averaged at known airflows over several breaths and that all measurements should be reported relative to sounds recorded at zero flow.

  19. Large fluctuations in the high-redshift metagalactic ionizing background

    NASA Astrophysics Data System (ADS)

    D'Aloisio, Anson; McQuinn, Matthew; Davies, Frederick B.; Furlanetto, Steven R.

    2018-01-01

    Recent observations have shown that the scatter in opacities amongst coeval segments of the Ly α forest increases rapidly at z > 5. In this paper, we assess whether the large scatter can be explained by fluctuations in the ionizing background in the post-reionization intergalactic medium. We find that matching the observed scatter at z ≈ 5.5 requires a short spatially averaged mean free path of 〈λmfp912〉 ≲ 15 h- 1 comoving Mpc, a factor of ≳3 shorter than direct measurements at z = 5.2. We argue that such rapid evolution in the mean free path is difficult to reconcile with our measurements of the global H I photoionization rate, which stay approximately constant over the interval z ≈ 4.8-5.5. However, we also show that measurements of the mean free path at z > 5 are likely biased towards higher values by the quasar proximity effect. This bias can reconcile the short values of 〈λmfp912〉 that are required to explain the large scatter in opacities. We discuss the implications of this scenario for cosmological reionization. Finally, we investigate whether other statistics applied to the z > 5 Ly α forest can shed light on the origin of the scatter. Compared to a model with a uniform ionizing background, models that successfully account for the scatter lead to enhanced power in the line-of-sight flux power spectrum on scales k ≲0.1 h Mpc-1. We find tentative evidence for this enhancement in observations of the high-redshift Ly α forest.

  20. The effects of aortic coarctation on cerebral hemodynamics and its importance in the etiopathogenesis of intracranial aneurysms.

    PubMed

    Singh, Pankaj K; Marzo, Alberto; Staicu, Cristina; William, Matt G; Wilkinson, Iain; Lawford, Patricia V; Rufenacht, Daniel A; Bijlenga, Philippe; Frangi, Alejandro F; Hose, Rodney; Patel, Umang J; Coley, Stuart C

    2010-01-01

    Hemodynamic changes in the cerebral circulation in presence of coarctation of aorta (CoA) and their significance in the increased intracranial aneurysms (IAs) formation in these patients remain unclear. In the present study, we measured the flow-rate waveforms in the cerebral arteries of a patient with CoA, followed by an analysis of different hemodynamic indices in a coexisting IA. Phase-contrast Magnetic Resonance (pc-MR) volumetric flow-rate (VFR) measurements were performed in cerebral arteries of a 51 years old woman with coexisting CoA, and five healthy volunteers. Numerical predictions of a number of relevant hemodynamic indices were performed in an IA located in sub-clinoid part of left internal carotid artery (ICA) of the patient. Computations were performed using Ansys(®)-CFX(™) solver using the VFR values measured in the patient as boundary conditions (BCs). A second analysis was performed using the average VFR values measured in healthy volunteers. The VFR waveforms measured in the patient and healthy volunteers were compared followed by a comparison of the hemodynamic indices obtained using both approaches. The results are discussed in the background of relevant literature. Mean flow-rates were increased by 27.1% to 54.9% (2.66-5.44 ml/sec) in the cerebral circulation of patients with CoA as compared to healthy volunteers (1.2-3.95 ml/sec). Velocities were increased inside the IA by 35-45%. An exponential rise of 650% was observed in the area affected by high wall shear stress (WSS>15Pa) when flow-rates specific to CoA were used as compared to population average flow-rates. Absolute values of space and time averaged WSS were increased by 65%. Whereas values of maximum pressure on the IA wall were increased by 15% the area of elevated pressure was actually decreased by 50%, reflecting a more focalized jet impingement within the IA of the CoA patient. IAs can develop in patients with CoA several years after the surgical repair. Cerebral flow-rates in CoA patients are significantly higher as compared to average flow-rates in healthy population. The increased supra-physiological WSS (>15Pa), OSI (>0.2) and focalized pressure may play an important role in the etiopathogenesis of IAs in patients with CoA.

  1. The Effects of Aortic Coarctation on Cerebral Hemodynamics and its Importance in the Etiopathogenesis of Intracranial Aneurysms

    PubMed Central

    Singh, Pankaj K; Marzo, Alberto; Staicu, Cristina; William, Matt G; Wilkinson, Iain; Lawford, Patricia V; Rufenacht, Daniel A; Bijlenga, Philippe; Frangi, Alejandro F; Hose, Rodney; Patel, Umang J; Coley, Stuart C

    2010-01-01

    Objectives: Hemodynamic changes in the cerebral circulation in presence of coarctation of aorta (CoA) and their significance in the increased intracranial aneurysms (IAs) formation in these patients remain unclear. In the present study, we measured the flow-rate waveforms in the cerebral arteries of a patient with CoA, followed by an analysis of different hemodynamic indices in a coexisting IA. Materials and Methods: Phase-contrast Magnetic Resonance (pc-MR) volumetric flow-rate (VFR) measurements were performed in cerebral arteries of a 51 years old woman with coexisting CoA, and five healthy volunteers. Numerical predictions of a number of relevant hemodynamic indices were performed in an IA located in sub-clinoid part of left internal carotid artery (ICA) of the patient. Computations were performed using Ansys®-CFX™ solver using the VFR values measured in the patient as boundary conditions (BCs). A second analysis was performed using the average VFR values measured in healthy volunteers. The VFR waveforms measured in the patient and healthy volunteers were compared followed by a comparison of the hemodynamic indices obtained using both approaches. The results are discussed in the background of relevant literature. Results: Mean flow-rates were increased by 27.1% to 54.9% (2.66–5.44 ml/sec) in the cerebral circulation of patients with CoA as compared to healthy volunteers (1.2–3.95 ml/sec). Velocities were increased inside the IA by 35–45%. An exponential rise of 650% was observed in the area affected by high wall shear stress (WSS>15Pa) when flow-rates specific to CoA were used as compared to population average flow-rates. Absolute values of space and time averaged WSS were increased by 65%. Whereas values of maximum pressure on the IA wall were increased by 15% the area of elevated pressure was actually decreased by 50%, reflecting a more focalized jet impingement within the IA of the CoA patient. Conclusions: IAs can develop in patients with CoA several years after the surgical repair. Cerebral flow-rates in CoA patients are significantly higher as compared to average flow-rates in healthy population. The increased supra-physiological WSS (>15Pa), OSI (>0.2) and focalized pressure may play an important role in the etiopathogenesis of IAs in patients with CoA. PMID:22518256

  2. Reduction of Averaging Time for Evaluation of Human Exposure to Radiofrequency Electromagnetic Fields from Cellular Base Stations

    NASA Astrophysics Data System (ADS)

    Kim, Byung Chan; Park, Seong-Ook

    In order to determine exposure compliance with the electromagnetic fields from a base station's antenna in the far-field region, we should calculate the spatially averaged field value in a defined space. This value is calculated based on the measured value obtained at several points within the restricted space. According to the ICNIRP guidelines, at each point in the space, the reference levels are averaged over any 6min (from 100kHz to 10GHz) for the general public. Therefore, the more points we use, the longer the measurement time becomes. For practical application, it is very advantageous to spend less time for measurement. In this paper, we analyzed the difference of average values between 6min and lesser periods and compared it with the standard uncertainty for measurement drift. Based on the standard deviation from the 6min averaging value, the proposed minimum averaging time is 1min.

  3. Modulation of thyroid hormone receptors by non-thyroidal stimuli

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ErkenBrack, D.E.; Clemons, G.K.

    1988-01-01

    The ability of non-thyroidal stimuli to affect the binding affinity and capacity of solubilized nuclear receptors for thyroid hormones was studied in a normal homeostatic system (erythropoiesis) and a pathobiologic one (lung-ozone interaction). No significant effects on affinity were found, as Kd control values for receptors derived from rat bone marrow averaged 57 (+/- 28) pM while experimental (hypoxic) values averaged 89 (+/- 55) pM. Kd control values in rat lung were found to average 142 (+/- 22) pM while average values derived from experimental protocols with ozone and methimazole were 267 (+/- 44) pM and 161 (+/- 35) pMmore » respectively. Finally, Kd control values for receptors derived from cultured MEL cells averaged 19 (+/- 2.6) pM while experimental values during exposure to DMSO or IGF1 were 23 (+/- 3.6) pM and 26 (+/- 11) pM respectively. In contrast, binding capacity (expressed as fmoles of hormone bound per unit protein of solubilized receptor) was markedly perturbed in several tissues by various agents: ozone effects on lung were shown by an average control value of 3.3 (+/- 0.4) as opposed to an experimental average of 28 (+/- 1.9); and hypoxia effects on erythroid tissue were displayed by an average control value of 0.7 (+/- 0.07) as opposed to the experimental figure of 1.8 (+/- 0.03). In cultured MEL cells, binding capacity was seen to be increased from control values of 388 (+/- 15) sites/cell to 1243 (+/- 142) sites/cell after DMSO exposure and 2002 (+/- 10) sites/cell after IGF1 exposure. Parallel experiments done with receptors derived from rat liver yielded values similar to those reported by other investigators and were unaffected by the experimental agents.« less

  4. Evaluation of the impact of wood combustion on benzo[a]pyrene (BaP) concentrations; ambient measurements and dispersion modeling in Helsinki, Finland

    NASA Astrophysics Data System (ADS)

    Hellén, Heidi; Kangas, Leena; Kousa, Anu; Vestenius, Mika; Teinilä, Kimmo; Karppinen, Ari; Kukkonen, Jaakko; Niemi, Jarkko V.

    2017-03-01

    Even though emission inventories indicate that wood combustion is a major source of polycyclic aromatic hydrocarbons (PAHs), estimating its impacts on PAH concentration in ambient air remains challenging. In this study the effect of local small-scale wood combustion on the benzo[a]pyrene (BaP) concentrations in ambient air in the Helsinki metropolitan area in Finland is evaluated, using ambient air measurements, emission estimates, and dispersion modeling. The measurements were conducted at 12 different locations during the period from 2007 to 2015. The spatial distributions of annual average BaP concentrations originating from wood combustion were predicted for four of those years: 2008, 2011, 2013, and 2014. According to both the measurements and the dispersion modeling, the European Union target value for the annual average BaP concentrations (1 ng m-3) was clearly exceeded in certain suburban detached-house areas. However, in most of the other urban areas, including the center of Helsinki, the concentrations were below the target value. The measured BaP concentrations highly correlated with the measured levoglucosan concentrations in the suburban detached-house areas. In street canyons, the measured concentrations of BaP were at the same level as those in the urban background, clearly lower than those in suburban detached-house areas. The predicted annual average concentrations matched with the measured concentrations fairly well. Both the measurements and the modeling clearly indicated that wood combustion was the main local source of ambient air BaP in the Helsinki metropolitan area.

  5. Formation of 2D bright spatial solitons in lithium niobate with photovoltaic response and incoherent background

    NASA Astrophysics Data System (ADS)

    Pustozerov, A.; Shandarov, V.

    2017-12-01

    The influence of incoherent background illumination produced by light-emitting diodes (LED's) of different average wavelengths and laser diode emitting in blue region of visible on diffraction characteristics of narrow coherent light beams of He-Ne laser due to refractive index changes of Fe-doped lithium niobate sample are studied. It has been experimentally demonstrated that nonlinear diffraction of red beams with wavelength 633 nm and diameters on full width of half maximum (FWHM) near to 15 μm may be totally compensated using background light with average wavelengths 450 - 465 nm. To provide the necessary intensity of incoherent background, the combinations of spherical and cylindrical concave lenses with blue LED and laser diode module without focusing its beam have been used.

  6. Natural radiation and its hazard in copper ore mines in Poland

    NASA Astrophysics Data System (ADS)

    Chau, Nguyen; Jodłowski, Paweł; Kalita, Stefan; Olko, Paweł; Chruściel, Edward; Maksymowicz, Adam; Waligórski, Michał; Bilski, Paweł; Budzanowski, Maciej

    2008-06-01

    The doses of gamma radiation, concentrations of radium isotopes in water and sediments, radon concentration and concentration of alpha potential energy of radon decay products in the copper ore mine and in the mining region in the vicinity of Lubin town in Poland are presented. These data served as a basis for the assessment of radiological hazard to the mine workers and general public. The results of this assessment indicate that radiological hazard in the region does not differ substantially from typical values associated with natural radiation background. The calculated average annual effective dose for copper miners is 1.48 mSv. In general, copper ore mines can be regarded as radiologically safe workplaces.

  7. Human face detection using motion and color information

    NASA Astrophysics Data System (ADS)

    Kim, Yang-Gyun; Bang, Man-Won; Park, Soon-Young; Choi, Kyoung-Ho; Hwang, Jeong-Hyun

    2008-02-01

    In this paper, we present a hardware implementation of a face detector for surveillance applications. To come up with a computationally cheap and fast algorithm with minimal memory requirement, motion and skin color information are fused successfully. More specifically, a newly appeared object is extracted first by comparing average Hue and Saturation values of background image and a current image. Then, the result of skin color filtering of the current image is combined with the result of a newly appeared object. Finally, labeling is performed to locate a true face region. The proposed system is implemented on Altera Cyclone2 using Quartus II 6.1 and ModelSim 6.1. For hardware description language (HDL), Verilog-HDL is used.

  8. 49 CFR 537.9 - Determination of fuel economy values and average fuel economy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 6 2014-10-01 2014-10-01 false Determination of fuel economy values and average fuel economy. 537.9 Section 537.9 Transportation Other Regulations Relating to Transportation... ECONOMY REPORTS § 537.9 Determination of fuel economy values and average fuel economy. (a) Vehicle...

  9. 49 CFR 537.9 - Determination of fuel economy values and average fuel economy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 6 2012-10-01 2012-10-01 false Determination of fuel economy values and average fuel economy. 537.9 Section 537.9 Transportation Other Regulations Relating to Transportation... ECONOMY REPORTS § 537.9 Determination of fuel economy values and average fuel economy. (a) Vehicle...

  10. 49 CFR 537.9 - Determination of fuel economy values and average fuel economy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false Determination of fuel economy values and average fuel economy. 537.9 Section 537.9 Transportation Other Regulations Relating to Transportation... ECONOMY REPORTS § 537.9 Determination of fuel economy values and average fuel economy. (a) Vehicle...

  11. 49 CFR 537.9 - Determination of fuel economy values and average fuel economy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 6 2011-10-01 2011-10-01 false Determination of fuel economy values and average fuel economy. 537.9 Section 537.9 Transportation Other Regulations Relating to Transportation... ECONOMY REPORTS § 537.9 Determination of fuel economy values and average fuel economy. (a) Vehicle...

  12. Profile of Prospective Physics Teachers on Assessment Literacy

    NASA Astrophysics Data System (ADS)

    Efendi, R.; Rustaman, N. Y.; Kaniawati, I.

    2017-02-01

    A study about assessment literacy of prospective Physics teachers was conducted with the involvement of 45 prospective physics teachers. Data collected by using test consisted of seven competencies. The profile of prospective physics teachers on assessment literacy determined in descriptive statistics, in the form of respondent average values. Research finding shows that prospective physics teachers were weak at all competency areas. The average values of the Choosing assessment methods appropriate for instructional decisions is the highest average values and the average values of the communicating assessment results to students, parents, other lay audiences, and other educators is the lowest average values. In depth study to detect the reason underlined the results was still in progress so far, as another aspect was planned to be administered on the next semester.

  13. Subjective Numeracy and the Influence of Order and Amount of Audible Information on Perceived Medication Value

    PubMed Central

    Fraenkel, Liana; Stolar, Marilyn; Swift, Sarah; Street, Richard L.; Chowdhary, Harjinder; Peters, Ellen

    2016-01-01

    Background Order and amount of information influence patients’ risk perceptions, but most studies have evaluated patients’ reactions to written materials. The objective of this study was to examine the effect of four communication strategies, varying in their order and/or amount of information, on judgments related to an audible description of a new medication and among patients who varied in subjective numeracy. Methods We created five versions of a hypothetical scenario describing a new medication. The versions were composed to elucidate whether order and/or amount of the information describing benefits and adverse events influenced how subjects valued a new medication. After listening to a randomly assigned version, perceived medication value was measured by asking subjects to choose one of the following statements: the risks outweigh the benefits, the risks and benefits are equally balanced, or the benefits outweigh the risks. Results Of the 432 patients contacted, 389 participated in the study. Listening to a brief description of benefits followed by an extended description of adverse events resulted in a greater likelihood of perceiving that the medication’s benefits outweighed the risks compared to: 1) presenting the extended adverse events description before the benefits, 2) giving a greater amount of information related to benefits, and 3) sandwiching the adverse events between benefits. These associations were only observed among subjects with average or higher subjective numeracy. Conclusion If confirmed in future studies, our results suggest that, for patients with average or better subjective numeracy, perceived medication value is highest when a brief presentation of benefits is followed by an extended description of adverse events. PMID:27216580

  14. Plasma Klotho and Cognitive Decline in Older Adults: Findings From the InCHIANTI Study

    PubMed Central

    Semba, Richard D.; Rosano, Caterina; Kalyani, Rita R.; Bandinelli, Stefania; Chia, Chee W.; Ferrucci, Luigi

    2016-01-01

    Background. The hormone klotho, encoded by the gene klotho, is primarily expressed in the kidney and choroid plexus of the brain. Higher klotho concentrations and certain genetic variants of klotho have been linked to better cognition; however, it is unknown whether klotho relates prospectively to slower cognitive decline in older adults. Methods: Plasma klotho was measured in 833 participants aged 55 or older without dementia enrolled in InCHIANTI, a prospective cohort study comprising Italian adults. Cognition was measured by Mini-Mental State Examination (MMSE) and Trail-Making Tests A and B (Trails A and Trails B) at enrollment and at 3 and 6 years after enrollment. We assessed whether klotho concentrations measured at the 3-year visit related to cognition and cognitive decline. Results: Each additional natural logarithm of klotho (pg/mL) was associated with 35% lower risk of meaningful decline in MMSE, defined as decline exceeding three points (relative risk = 0.65; 95% confidence interval 0.45, 0.95; p value = .02), and 0.75-point smaller average 3-year decline (baseline to 3-year visit) in MMSE (95% confidence interval 0.02, 1.48; p value = .04). No statistically significant associations were found between klotho and declining Trails A (relative risk = 0.99; 95% confidence interval 0.75, 1.32; p value = .97) and B (relative risk = 1.02; 95% confidence interval 0.84, 1.24; p value = .82). Conclusions: Higher plasma klotho concentrations were associated with lower risk of meaningful decline and smaller average decline in MMSE. We did not observe such findings with Trails A and B, perhaps because they test executive function and motor skills, whereas MMSE measures global cognition. Future studies should investigate mechanisms through which klotho may affect domain-specific cognitive changes. PMID:26297657

  15. Scanning linear estimation: improvements over region of interest (ROI) methods

    NASA Astrophysics Data System (ADS)

    Kupinski, Meredith K.; Clarkson, Eric W.; Barrett, Harrison H.

    2013-03-01

    In tomographic medical imaging, a signal activity is typically estimated by summing voxels from a reconstructed image. We introduce an alternative estimation scheme that operates on the raw projection data and offers a substantial improvement, as measured by the ensemble mean-square error (EMSE), when compared to using voxel values from a maximum-likelihood expectation-maximization (MLEM) reconstruction. The scanning-linear (SL) estimator operates on the raw projection data and is derived as a special case of maximum-likelihood estimation with a series of approximations to make the calculation tractable. The approximated likelihood accounts for background randomness, measurement noise and variability in the parameters to be estimated. When signal size and location are known, the SL estimate of signal activity is unbiased, i.e. the average estimate equals the true value. By contrast, unpredictable bias arising from the null functions of the imaging system affect standard algorithms that operate on reconstructed data. The SL method is demonstrated for two different tasks: (1) simultaneously estimating a signal’s size, location and activity; (2) for a fixed signal size and location, estimating activity. Noisy projection data are realistically simulated using measured calibration data from the multi-module multi-resolution small-animal SPECT imaging system. For both tasks, the same set of images is reconstructed using the MLEM algorithm (80 iterations), and the average and maximum values within the region of interest (ROI) are calculated for comparison. This comparison shows dramatic improvements in EMSE for the SL estimates. To show that the bias in ROI estimates affects not only absolute values but also relative differences, such as those used to monitor the response to therapy, the activity estimation task is repeated for three different signal sizes.

  16. A Computationally Efficient Filter for Reducing Shot Noise in Low S/N Data

    PubMed Central

    Okada, Mami; Ishikawa, Tomoe; Ikegaya, Yuji

    2016-01-01

    Functional multineuron calcium imaging (fMCI) provides a useful experimental platform to simultaneously capture the spatiotemporal patterns of neuronal activity from a large cell population in situ. However, fMCI often suffers from low signal-to-noise ratios (S/N). The main factor that causes the low S/N is shot noise that arises from photon detectors. Here, we propose a new denoising procedure, termed the Okada filter, which is designed to reduce shot noise under low S/N conditions, such as fMCI. The core idea of the Okada filter is to replace the fluorescence intensity value of a given frame time with the average of two values at the preceding and following frames unless the focused value is the median among these three values. This process is iterated serially throughout a time-series vector. In fMCI data of hippocampal neurons, the Okada filter rapidly reduces background noise and significantly improves the S/N. The Okada filter is also applicable for reducing shot noise in electrophysiological data and photographs. Finally, the Okada filter can be described using a single continuous differentiable equation based on the logistic function and is thus mathematically tractable. PMID:27304217

  17. Regional trace gas monitoring simplified - A linear retrieval scheme for carbon monoxide from hyperspectral soundings

    NASA Astrophysics Data System (ADS)

    Smith, N.; Huang, A.; Weisz, E.; Annegarn, H. J.

    2011-12-01

    The Fast Linear Inversion Trace gas System (FLITS) is designed to retrieve tropospheric total column trace gas densities [molec.cm-2] from space-borne hyperspectral infrared soundings. The objective to develop a new retrieval scheme was motivated by the need for near real-time air quality monitoring at high spatial resolution. We present a case study of FLITS carbon monoxide (CO) retrievals from daytime (descending orbit) Infrared Atmospheric Sounding Interferometer (IASI) measurements that have a 0.5 cm-1 spectral resolution and 12 km footprint at nadir. The standard Level 2 IASI CO retrieval product (COL2) is available in near real-time but is spatially averaged over 2 x 2 pixels, or 50 x 50 km, and thus more suitable for global analysis. The study region is Southern Africa (south of the equator) for the period 28-31 August 2008. An atmospheric background estimate is obtained from a chemical transport model, emissivity from regional measurements and surface temperature (ST) from space-borne retrievals. The CO background error is set to 10%. FLITS retrieves CO by assuming a simple linear relationship between the IASI measurements and background estimate of the atmosphere and surface parameters. This differs from the COL2 algorithm that treats CO retrieval as a moderately non-linear problem. When compared to COL2, the FLITS retrievals display similar trends in distribution and transport of CO over time with the advantage of an improved spatial resolution (single-pixel). The value of the averaging kernel (A) is consistently above 0.5 and indicates that FLITS retrievals have a stable dependence on the measurement. This stability is achieved through careful channel selection in the strongest CO absorption lines (2050-2225 cm-1) and joint retrieval with skin temperature (IASI sensitivity to CO is highly correlated with ST), thus no spatial averaging is necessary. We conclude that the simplicity and stability of FLITS make it useful first as a research tool, i.e. the algorithm is easy to understand and computationally simple enough to run on most desktop computers, and second, as an operational tool that can calculate near real-time CO retrievals at instrument resolution for regional monitoring.

  18. [RELATIONSHIP BETWEEN THE PREVALENCE OF CHRONIC NONINFECTIOUS DISEASES AND ELECTROPHYSICAL STATE OF THE ENVIRONMENT].

    PubMed

    Rakhmanin, Yu A; Stekhin, A A; Yakovleva, G V; Karasev, A K; Marasanov, A V; Iksanova, T I; Ryabikov, V V

    2015-01-01

    In the paper there is evaluated the relationship of features of electronic state of the environment with a level of chronic, noninfectious diseases (CNID) in the regions of Russia, obtained on the basis of the monitoring measurements of the intensity of natural background electronic Bose condensate (BEBC) of natural ecosystems in a number of Russian regions and seas of the Arctic Ocean. The assessment of BEBC was implemented on results of measurements of redox state of distilled water being in the contact with natural water. The equilibrium redox state of distilled water, determined by the influx of electrons (quantum reduction) outside, is proportional to the intensity of BEBC. The obtained data attest to an increase in the intensity of the background of EBC in Siberia regions and, especially, within the limits ofwaters of Lake Baikal (the redox potential of the surface water in the lake ~ -70mV). Also there is observed a strong dependence of the background EBC in the latitudinal direction. Low levels of background EBC were noted in the Arkhangelsk region and the north-eastern Chukotka. Functioning of international systems of plasma sounding of ionosphere (such systems as HAARP) were established to have a detrimental effect on the background EBC in these regions. According to the results of measurements of the relative values of intensities of natural background of Bose condensate of electrons there was constructed the dependence reflecting the relationship of the prevalence of noninfectious diseases in the regions of Russia with the redox state of distilled water which can be characterized as a significant (regression coefficient R2 = 0.78). The relationship between noninfectious diseases (NID, %) with the intensity of the background of EBC (Ib rel. units) is estimated by the equation: NID [%] = 0.24Eh [mV]-25, where Eh ~ I/Ib. Numerical evaluations show that an increase in the biosphere redox potential of water by 90mV leads to an increase of the primary incidence by 20% (relatively to the average values for Russia). Analysis of results attests to the relationship of CNID with the electrophysical state of the environment that allows from different positions to arrive to true causes of their emergence, associated with changes in the electrophysical conditions of habitation and human activities that lead to the nascency of cellular metabolic disturbances.

  19. Natural gamma-radiation in the Aeolian volcanic arc.

    PubMed

    Chiozzi, P; Pasquale, V; Verdoya, M; Minato, S

    2001-11-01

    Pulse-height distributions of gamma-rays, obtained with a field NaI(Tl) scintillation spectrometer in numerous sites of the Lipari and Vulcano islands (Aeolian volcanic arc, Italy), were measured to determine the U, Th and K concentrations of the bedrock and the relative values of the air absorbed dose rate. U is spatially related to both Th and K and the Th/U ratio is on average 3.1-3.5. The magmatic evolution is reflected by the concentration of the three radioelements, as they are more abundant within the more felsic units of the volcanic series. The higher values of U (15.7-20.0 ppm) coincide with higher Th (48.3-65.9 ppm) and K (4.9-6.1%) concentrations associated with rhyolitic rocks of the third cycle (< 50 ky). The air absorbed dose rate varies from 20 to 470 nGy h(-1). The highest values (> 350 nGy h(-1)) are observed on outcrops of rhyolitic obsidian lava flows. The cosmic-ray contribution is also evaluated to estimate the total background radiation dose rate.

  20. Assessment of natural radioactivity and gamma-ray dose in monazite rich black Sand Beach of Penang Island, Malaysia.

    PubMed

    Shuaibu, Hauwau Kulu; Khandaker, Mayeen Uddin; Alrefae, Tareq; Bradley, D A

    2017-06-15

    Activity concentrations of primordial radionuclides in sand samples collected from the coastal beaches surrounding Penang Island have been measured using conventional γ-ray spectrometry, while in-situ γ-ray doses have been measured through use of a portable radiation survey meter. The mean activity concentrations for 226 Ra, 232 Th and 40 K at different locations were found to be less than the world average values, while the Miami Bay values for 226 Ra and 232 Th were found to be greater, at 1023±47 and 2086±96Bqkg ̶ 1 respectively. The main contributor to radionuclide enrichment in Miami Bay is the presence of monazite-rich black sands. The measured data were compared against literature values and also recommended limits set by the relevant international bodies. With the exception of Miami Bay, considered an elevated background radiation area that would benefit from regular monitoring, Penang island beach sands typically pose no significant radiological risk to the local populace and tourists visiting the leisure beaches. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Heavy Metals in Surface Soils in the Upper Reaches of the Heihe River, Northeastern Tibetan Plateau, China

    PubMed Central

    Bu, Jianwei; Sun, Ziyong; Zhou, Aiguo; Xu, Youning; Ma, Rui; Wei, Wenhao; Liu, Meng

    2016-01-01

    The upper reaches of the Heihe River have been regarded as a hotspot for phytoecology, climate change, water resources and hydrology studies. Due to the cold-arid climate, high elevation, remote location and poor traffic conditions, few studies focused on heavy metal contamination of soils have been conducted or reported in this region. In the present study, an investigation was performed to provide information regarding the concentration levels, sources, spatial distributions, and environmental risks of heavy metals in this area for the first time. Fifty-six surface soil samples collected from the study area were analyzed for Cr, Mn, Ni, Cu, Zn, As, Cd and Pb concentrations, as well as TOC levels. Basic statistics, concentration comparisons, correlation coefficient analysis and multivariate analyses coupled with spatial distributions were utilized to delineate the features and the sources of different heavy metals. Risk assessments, including geoaccumulation index, enrichment factor and potential ecological risk index, were also performed. The results indicate that the concentrations of heavy metals have been increasing since the 1990s. The mean values of each metal are all above the average background values in the Qinghai Province, Tibet, China and the world, except for that of Cr. Of special note is the concentration of Cd, which is extremely elevated compared with all background values. The distinguished ore-forming conditions and well-preserved, widely distributed limestones likely contribute to the high Cd concentration. Heavy metals in surface soils in the study area are primarily inherited from parent materials. Nonetheless, anthropogenic activities may have accelerated the process of weathering. Cd presents a high background concentration level and poses a severe environmental risk throughout the whole region. Soils in Yinda, Reshui daban, Kekeli and Zamasheng in particular pose threats to the health of the local population, as well as that of livestock and wildlife. PMID:26907322

  2. Dust fallout in Kuwait city: deposition and characterization.

    PubMed

    Al-Awadhi, Jasem M; Alshuaibi, Arafat A

    2013-09-01

    Dust fallouts in Kuwait city was monitored on monthly basis during the period from March 2011 to February 2012 at 10 locations. The results of this study reveal that: (1) monthly dust deposition rates ranged from 0.002 to 0.32 kg/m(2) with average deposition rate of 0.053 kg/m(2) and annual average deposition rate of 0.59 kg/m(2), ranking the first out of 56 dust deposition rates observed throughout the world; (2) on average, about 55.9% of the settled dust have fine to very fine sand fraction sizes, while silt and clay comprise an average of 37.4 and 1.4% of the total sample, respectively; (3) the concentrations for Zn and Mo out of 15 other elements analyzed from the dust were up to 11 times higher than their soil background values in Kuwait, while Pb and Ni were about seven times higher; (4) Mo, Ni, Pb and Zn show maximum enrichment relative to the upper continental crustal component (Mn); (5) Sr, Zr and Zn show highest concretions among all collected samples; and (6) quartz and calcite were the dominant minerals in the dust samples. The distribution of the heavy metals in dust seems to be controlled mainly by the land uses and the volume of traffic emissions. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. [In-situ measurement of atmospheric methyl chloroform at the Shangdianzi GAW regional background station].

    PubMed

    Yao, Bo; Zhou, Ling-Xi; Liu, Zhao; Zhang, Gen; Xia, Ling-Jun

    2014-07-01

    An in-situ GC-ECD monitoring system was established at the Shangdianzi GAW regional background station (SDZ) for a 2-year atmospheric methyl chloroform (CH3CCl3) measurement experiment. Robust extraction of baseline signal filter was applied to the CH3CCl3 time series to separate the background and pollution data. The yearly averaged background mixing ratios of atmospheric CH3CCl3 were (9.03 +/- 0.53) x 10(-12) mol x mol(-1) in 2009 and (7.73 +/- 0.47) x 10(-12) in 2010, and the percentages of the background data in the whole data were 61.1% in 2009 and 60.4% in 2010, respectively. The yearly background CH3CCl3 mixing ratios at SDZ were consistent with the northern hemisphere background levels observed at Mace Head and Trinidad Head stations, but lower than the results observed at sites in southern China and some Chinese cities from 2001 to 2005. During the study period, background mixing ratios trends exhibited a decreasing rate of 1.39 x 10 12(-12) a(-1). The wind direction with the maximum CH3CCl3 mixing ratio was from the southwest sector and that with the minimum ratio was from the northeast sector. The differences between the maximum and the minimum average mixing ratios in the 16 wind directions were 0.77 x 10(-12) (2009) and 0.52 x 10(-12) (2010). In the 16 different wind directions, the averaged mixing ratio of CH3CCl3 in 2010 was lower than that in 2009 by 1.03 x 10(-12) -1.68 x 10(-12).

  4. The relation of severe malnutrition in infancy to the intelligence of school children with differing life histories.

    PubMed

    Richardson, S A

    1976-01-01

    The IQ's of Jamaican boys aged 6-10 were associated significantly with the presence or absence of severe malnutrition in infancy, with height at time of IQ testing, and with a measure of the boys' social background. A multiple correlation coefficient of 0.674 was obtained between IQ and the three factors. Social background contributed 0.294 of the variance, height 0.112, and severe malnutrition 0.049. The two extreme groups of boys, i.e., those malnourished, small at follow-up, and with unfavorable social backgrounds and those not malnourished, tall at follow-up, and with favorable social backgrounds had average IQ's of 49.4 and 74.9, respectively (from Table 5). Only two of the boys in the most advantaged group had IQ scores that overlapped with the most disadvantaged group. Boys with severe malnutrition in infancy, but who are tall at follow-up and have a favorable social background have an average IQ 11 points higher than boys who did not experience severe malnutrition, but who are short at follow-up and have a unfavorable social background. The difference in IQ between boys who did and did not experience severe malnutrition in infancy varies under different conditions of height and social background when those are held constant for both groups. Under the most favorable conditions of being tall and having an advantageous social history the average IQ of the malnourtished boys in only 2 points lower than those not malnourished. Unde the most unfavorable conditions of short stature and a disadvantageous social background the IQ of the malnourished boys is 9 points lower than those not malnourished (Table 6 and Fig. 1).

  5. ViBe: a universal background subtraction algorithm for video sequences.

    PubMed

    Barnich, Olivier; Van Droogenbroeck, Marc

    2011-06-01

    This paper presents a technique for motion detection that incorporates several innovative mechanisms. For example, our proposed technique stores, for each pixel, a set of values taken in the past at the same location or in the neighborhood. It then compares this set to the current pixel value in order to determine whether that pixel belongs to the background, and adapts the model by choosing randomly which values to substitute from the background model. This approach differs from those based upon the classical belief that the oldest values should be replaced first. Finally, when the pixel is found to be part of the background, its value is propagated into the background model of a neighboring pixel. We describe our method in full details (including pseudo-code and the parameter values used) and compare it to other background subtraction techniques. Efficiency figures show that our method outperforms recent and proven state-of-the-art methods in terms of both computation speed and detection rate. We also analyze the performance of a downscaled version of our algorithm to the absolute minimum of one comparison and one byte of memory per pixel. It appears that even such a simplified version of our algorithm performs better than mainstream techniques.

  6. Computation of bedrock-aquifer recharge in northern Westchester County, New York, and chemical quality of water from selected bedrock wells

    USGS Publications Warehouse

    Wolcott, Stephen W.; Snow, Robert F.

    1995-01-01

    An empirical technique was used to calculate the recharge to bedrock aquifers in northern Westchester County. This method requires delineation of ground-water divides within the aquifer area and values for (1) the extent of till and exposed bedrock within the aquifer area, and (2) mean annual runoff. This report contains maps and data needed for calculation of recharge in any given area within the 165square-mile study area. Recharge was computed by this technique for a 93-square-mile part of the study area and used a ground-water-flow model to evaluate the reliability of the method. A two-layer, steady-state model of the selected area was calibrated. The area consists predominantly of bedrock overlain by small localized deposits of till and stratified drill Ground-water-level and streamflow data collected in mid-November 1987 were used for model calibration. The data set approximates average annual conditions. The model was calibrated from (1) estimates of recharge as computed through the empirical technique, and (2) a range of values for hydrologic properties derived from aquifer tests and published literature. Recharge values used for model simulation appear to be reasonable for average steady-state conditions. Water-quality data were collected from 53 selected bedrock wells throughout northern Westchester County to define the background ground-water quality. The constituents and properties for which samples were analyzed included major cations and anions, temperature, pH, specific conductance, and hardness. Results indicate little difference in water quality among the bedrock aquifers within the study area. Ground water is mainly the calcium-bicarbonate type and is moderately hard. Average concentrations of sodium, sulfate, chloride, nitrate, iron, and manganese were within acceptable limits established by the U.S. Environmental Protection Agency for domestic water supply.

  7. HOSPITALIZATIONS FOR CHOLECYSTITIS AND CHOLELITHIASIS IN THE STATE OF RIO GRANDE DO SUL, BRAZIL

    PubMed Central

    NUNES, Emeline Caldana; ROSA, Roger dos Santos; BORDIN, Ronaldo

    2016-01-01

    ABSTRACT Background: The cholelithiasis is disease of surgical resolution with about 60,000 hospitalizations per year in the Sistema Único de Saúde (SUS - Brazilian National Health System) of the Rio Grande do Sul state. Aim: To describe the profile of hospitalizations for cholecystitis and cholelithiasis performed by the SUS of Rio Grande do Sul state, 2011-2013. Methods: Hospital Information System data from the National Health System through morbidity list for cholelithiasis and cholecystitis (ICD-10 K80-K81). Variables studied were sex, age, number of hospitalizations and approved Hospitalization Authorizations (AIH), total amount and value of hospital services generated, days and average length of stay, mortality, mortality and case fatality ratio, from health regions of the Rio Grande do Sul. Results: During 2011-2013 there were 60,517 hospitalizations for cholecystitis and cholelithiasis, representing 18.86 hospitalizations per 10,000 inhabitants/year, most often in the age group from 60 to 69 years (41.34 admissions per 10,000 inhabitants/year) and female (27.72 hospitalizations per 10,000 inhabitants/year). The fatality rate presented an inverse characteristic: 13.52 deaths per 1,000 admissions/year for males, compared with 7.12 deaths per 1,000 admissions/year in females. The state had an average total amount spent and value of hospital services of R$ 16,244,050.60 and R$ 10,890,461.31, respectively. The health region "Capital/Gravataí Valley" exhibit the highest total expenditure and hospital services, and the largest number of deaths, and average length of stay. Conclusion: The hospitalization and lethality coefficients, the deaths, the length of stay and spending related to admissions increased from 50 years old. Females had a higher frequency and higher values ​​spent on hospitalization, while the male higher coefficient of mortality and mean hospital stay. PMID:27438030

  8. In Tropical Lowland Rain Forests Monocots have Tougher Leaves than Dicots, and Include a New Kind of Tough Leaf

    PubMed Central

    Dominy, Nathaniel J.; Grubb, Peter J.; Jackson, Robyn V.; Lucas, Peter W.; Metcalfe, Daniel J.; Svenning, Jens-Christian; Turner, Ian M.

    2008-01-01

    Background and Aims There has been little previous work on the toughness of the laminae of monocots in tropical lowland rain forest (TLRF) despite the potential importance of greater toughness in inhibiting herbivory by invertebrates. Of 15 monocot families with >100 species in TLRF, eight have notably high densities of fibres in the lamina so that high values for toughness are expected. Methods In north-eastern Australia punch strength was determined with a penetrometer for both immature leaves (approx. 30 % final area on average) and fully expanded, fully toughened leaves. In Singapore and Panama, fracture toughness was determined with an automated scissors apparatus using fully toughened leaves only. Key Results In Australia punch strength was, on average, 7× greater in shade-tolerant monocots than in neighbouring dicots at the immature stage, and 3× greater at the mature stage. In Singapore, shade-tolerant monocots had, on average, 1·3× higher values for fracture toughness than neighbouring dicots. In Panama, both shade-tolerant and gap-demanding monocots were tested; they did not differ in fracture toughness. The monocots had markedly higher values than the dicots whether shade-tolerant or gap-demanding species were considered. Conclusions It is predicted that monocots will be found to experience lower rates of herbivory by invertebrates than dicots. The tough monocot leaves include both stiff leaves containing relatively little water at saturation (e.g. palms), and leaves which lack stiffness, are rich in water at saturation and roll readily during dry weather or even in bright sun around midday (e.g. gingers, heliconias and marants). Monocot leaves also show that it is possible for leaves to be notably tough throughout the expansion phase of development, something never recorded for dicots. The need to broaden the botanist's mental picture of a ‘tough leaf’ is emphasized. PMID:18387969

  9. Signal-averaged P wave in patients with paroxysmal atrial fibrillation.

    PubMed

    Rosenheck, S

    1997-10-01

    The theoretical and experimental rational of atrial signal-averaged ECG in patients with AF is delay in the intra-atrial and interatrial conduction. Similar to the ventricular signal-averaged ECG, the atrial signal-averaged ECG is an averaging of a high number of consecutive P waves that match the template created earlier P wave triggering is preferred over QRS triggering because of more accurate aligning. However, the small amplitude of the atrial ECG and its gradual increase from the isoelectric line may create difficulties in defining the start point if P wave triggering is used. Studies using P wave triggering and those using QRS triggering demonstrate a prolonged P wave duration in patients with paroxysmal AF. The negative predictive value of this test is relatively high at 60%-80%. The positive predictive value of atrial signal-averaged ECGs in predicting the risk of AF is considerably lower than the negative predictive value. All the data accumulated prospectively on the predictive value of P wave signal-averaging was determined only in patients undergoing coronary bypass surgery or following MI; its value in other patients with paroxysmal AF is still not determined. The clinical role of frequency-domain analysis (alone or added to time-domain analysis) remains undefined. Because of this limited knowledge on the predictive value of P wave signal-averaging, it is still not clinical medicine, and further research is needed before atrial signal-averaged ECG will be part of clinical testing.

  10. Studies of Isolated and Non-isolated Photospheric Bright Points in an Active Region Observed by the New Vacuum Solar Telescope

    NASA Astrophysics Data System (ADS)

    Liu, Yanxiao; Xiang, Yongyuan; Erdélyi, Robertus; Liu, Zhong; Li, Dong; Ning, Zongjun; Bi, Yi; Wu, Ning; Lin, Jun

    2018-03-01

    Properties of photospheric bright points (BPs) near an active region have been studied in TiO λ 7058 Å images observed by the New Vacuum Solar Telescope of the Yunnan Observatories. We developed a novel recognition method that was used to identify and track 2010 BPs. The observed evolving BPs are classified into isolated (individual) and non-isolated (where multiple BPs are observed to display splitting and merging behaviors) sets. About 35.1% of BPs are non-isolated. For both isolated and non-isolated BPs, the brightness varies from 0.8 to 1.3 times the average background intensity and follows a Gaussian distribution. The lifetimes of BPs follow a log-normal distribution, with characteristic lifetimes of (267 ± 140) s and (421 ± 255) s, respectively. Their size also follows log-normal distribution, with an average size of about (2.15 ± 0.74) × 104 km2 and (3.00 ± 1.31) × 104 km2 for area, and (163 ± 27) km and (191 ± 40) km for diameter, respectively. Our results indicate that regions with strong background magnetic field have higher BP number density and higher BP area coverage than regions with weak background field. Apparently, the brightness/size of BPs does not depend on the background field. Lifetimes in regions with strong background magnetic field are shorter than those in regions with weak background field, on average.

  11. Spectrophotometric Measurement of Minimal Erythema Dose Sites after Narrowband Ultraviolet B Phototesting: Clinical Implication of Spetrophotometric Values in Phototherapy

    PubMed Central

    Jeon, Su-Young; Lee, Chae-Young; Song, Ki-Hoon

    2014-01-01

    Background The spectrophotometer is well known to be a useful tool for estimating the objective minimal erythema dose (MED) during planning of phototherapy protocol. However, only a few spectrophotometric values are used to evaluate the erythema and pigmentation of the MED site during phototesting. Objective To determinea new meaning of the relationships among spectrophotometric values during phototesting. Methods Twenty-five patients with psoriasis and 23 patients with vitiligo were selected before undergoing narrowband ultraviolet B phototherapy. We interpreted the gross findings of erythema and measured the L*a*b* values using a spectrophotometer at each phototest spot. We compared MEDs, basic spectrophotometric values (L*a*b*), and b*/L* values separately according to skin type, and determined the correlation of each spectrophotometric value and the correlation between a* and b*/L* values. Results Among L*a*b* values, only b* values showed a statistically significant difference between the type III and IV groups (p=0.003). There was a positive correlation only between MEDs and b* values (p<0.05). The average b*/L*value in the type IV group was significantly higher than the type III group (p<0.05). Conclusion The higher b* values in type IV skin indicates that skin tanning develops more prominently than type III. The correlation between MEDs and b* values may signify that the skin pigmentation status is deepened with the higher MEDs. The difference in b*/L*values between type III and IV skin reflects that the b*/L*value is thought to be an index of tanning. The a* value, known as an index of erythema, does not influence the degree of tanning. PMID:24648682

  12. Radiative Characteristics of Aerosol During Extreme Fire Event over Siberia in Summer 2012

    NASA Technical Reports Server (NTRS)

    Zhuravleva, Tatiana B.; Kabanov, Dmitriy M.; Nasrtdinov, Ilmir M.; Russkova, Tatiana V.; Sakerin, Sergey M.; Smirnov, Alexander; Holben, Brent N.

    2017-01-01

    Microphysical and optical properties of aerosol were studied during a mega-fire event in summer 2012 over Siberia using ground-based measurements of spectral solarradiation at the AERONET site in Tomsk and satellite observations. The data were analyzed using multi-year (2003-2013) measurements of aerosol characteristics under back-ground conditions and for less intense fires, differing in burning biomass type, stage of fire, remoteness from observation site, etc. (ordinary smoke). In June-August 2012, the average aerosol optical depth (AOD, 500 nm) had been 0.95+/-0.86, about a factor of 6 larger than background values (0.16+/-0.08), and a factor of 2.5 larger than in ordinary smoke. The AOD values were extremely high on 24-28 July and reached 3-5. A comparison with satellite observations showed that ground-based measurements in the region of Tomsk not only reflect the local AOD features, but are also characteristic for the territory of Western Siberia as a whole. Single scattering albedo (SSA, 440 nm) in this period ranged from 0.91 to 0.99 with an average of approx. 0.96 in the entire wavelength range of 440-1020 nm. The increase in absorptance of aerosol particles (SSA(440 nm)=0.92) and decrease in SSA with wavelength observed in ordinary smoke agree with the data from multi-year observations in analogous situations in the boreal zone of USA and Canada. Volume aerosol size distribution in extreme and ordinary smoke had a bimodal character with significant prevalence of fine-mode particles, but in summer 2012 the mean median radius and the width of the fine-mode distribution somewhat increased. In contrast to data from multi-year observations, in summer 2012 an increase in the volume concentration and median radius of the coarse mode was observed with growing AOD.

  13. Natural variation in 210Po and 210Pb activity concentrations in the urine of Finnish population groups.

    PubMed

    Muikku, Maarit; Heikkinen, Tarja; Solatie, Dina; Vesterbacka, Pia

    2011-11-01

    A study to determine activity concentrations of (210)Pb and (210)Po in the urine of certain Finnish population groups was conducted, to investigate the variation in natural background level of urinary excretion. The study participants were divided into three groups mainly based on their diet. The first group comprised recreational fishermen and the second group represented people consuming more reindeer meat than an average Finn, while people using drinking water with very high activity concentrations of (210)Po were selected for the third group. The fourth group was a control group. The mean urinary excretion of (210)Po in groups 1 and 2 was 73 and 100 mBq d(-1), respectively. These values were higher than the value of the control group (20 mBq d(-1)) and the mean values reported in the literature. The mean daily urinary excretion of (210)Pb in groups 1 and 2, 70 and 52 mBq d(-1), was also slightly higher than that in the control group (32 mBq d(-1)). In contrast, the excretion rates of both (210)Po and (210)Pb for the members of group 3 were one to two orders of magnitude higher than those reported in the literature. This was clearly due to the elevated levels of natural radionuclides in their drinking water. The present study demonstrates the importance of possessing good knowledge of the background levels, in order to allow the determination of the additional exposure due, for example, to the malevolent use of radiation.

  14. Assessment of impact of urbanisation on background radiation exposure and human health risk estimation in Kuala Lumpur, Malaysia.

    PubMed

    Sanusi, M S M; Ramli, A T; Hassan, W M S W; Lee, M H; Izham, A; Said, M N; Wagiran, H; Heryanshah, A

    2017-07-01

    Kuala Lumpur has been undergoing rapid urbanisation process, mainly in infrastructure development. The opening of new township and residential in former tin mining areas, particularly in the heavy mineral- or tin-bearing alluvial soil in Kuala Lumpur, is a contentious subject in land-use regulation. Construction practices, i.e. reclamation and dredging in these areas are potential to enhance the radioactivity levels of soil and subsequently, increase the existing background gamma radiation levels. This situation is worsened with the utilisation of tin tailings as construction materials apart from unavoidable soil pollutions due to naturally occurring radioactive materials in construction materials, e.g. granitic aggregate, cement and red clay brick. This study was conducted to assess the urbanisation impacts on background gamma radiation in Kuala Lumpur. The study found that the mean value of measured dose rate was 251±6nGyh -1 (156-392nGyh -1 ) and 4 times higher than the world average value. High radioactivity levels of 238 U (95±12Bqkg -1 ), 232 Th (191±23Bqkg -1 ,) and 40 K (727±130Bqkg -1 ) in soil were identified as the major source of high radiation exposure. Based on statistical ANOVA, t-test, and analyses of cumulative probability distribution, this study has statistically verified the dose enhancements in the background radiation. The effective dose was estimated to be 0.31±0.01mSvy -1 per man. The recommended ICRP reference level (1-20mSvy -1 ) is applicable to the involved existing exposure situation in this study. The estimated effective dose in this study is lower than the ICRP reference level and too low to cause deterministic radiation effects. Nevertheless based on estimations of lifetime radiation exposure risks, this study found that there was small probability for individual in Kuala Lumpur being diagnosed with cancer and dying of cancer. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Acetylcholine receptor gating at extracellular transmembrane domain interface: the "pre-M1" linker.

    PubMed

    Purohit, Prasad; Auerbach, Anthony

    2007-12-01

    Charged residues in the beta10-M1 linker region ("pre-M1") are important in the expression and function of neuromuscular acetylcholine receptors (AChRs). The perturbation of a salt bridge between pre-M1 residue R209 and loop 2 residue E45 has been proposed as being a principle event in the AChR gating conformational "wave." We examined the effects of mutations to all five residues in pre-M1 (positions M207-P211) plus E45 in loop 2 in the mouse alpha(1)-subunit. M207, Q208, and P211 mutants caused small (approximately threefold) changes in the gating equilibrium constant (K(eq)), but the changes for R209, L210, and E45 were larger. Of 19 different side chain substitutions at R209 on the wild-type background, only Q, K, and H generated functional channels, with the largest change in K(eq) (67-fold) from R209Q. Various R209 mutants were functional on different E45 backgrounds: H, Q, and K (E45A), H, A, N, and Q (E45R), and K, A, and N (E45L). Phi values for R209 (on the E45A background), L210, and E45 were 0.74, 0.35, and 0.80, respectively. Phi values for R209 on the wt and three other backgrounds could not be estimated because of scatter. The average coupling energy between 209/45 side chains (six different pairs) was only -0.33 kcal/mol (for both alpha subunits, combined). Pre-M1 residues are important for expression of functional channels and participate in gating, but the relatively modest changes in closed- vs. open-state energy caused mutations, the weak coupling energy between these residues and the functional activity of several unmatched-charge pairs are not consistent with the perturbation of a salt bridge between R209 and E45 playing the principle role in gating.

  16. Semi-annual Sq-variation in solar activity cycle

    NASA Astrophysics Data System (ADS)

    Pogrebnoy, V.; Malosiev, T.

    The peculiarities of semi-annual variation in solar activity cycle have been studied. The data from observatories having long observational series and located in different latitude zones were used. The following observatories were selected: Huancayo (magnetic equator), from 1922 to 1959; Apia (low latitudes), from 1912 to 1961; Moscow (middle latitudes), from 1947 to 1965. Based on the hourly values of H-components, the average monthly diurnal amplitudes (a difference between midday and midnight values), according to five international quiet days, were computed. Obtained results were compared with R (relative sunspot numbers) in the ranges of 0-30R, 40-100R, and 140-190R. It was shown, that the amplitude of semi-annual variation increases with R, from minimum to maximum values, on average by 45%. At equatorial Huancayo observatory, the semi-annual Sq(H)-variation appears especially clearly: its maximums take place at periods of equinoxes (March-April, September-October), and minimums -- at periods of solstices (June-July, December-January). At low (Apia observatory) and middle (Moscow observatory) latitudes, the character of semi-annual variation is somewhat different: it appears during the periods of equinoxes, but considerably less than at equator. Besides, with the growth of R, semi-annual variation appears against a background of annual variation, in the form of second peaks (maximum in June). At observatories located in low and middle latitudes, second peaks become more appreciable with an increase of R (March-April and September-October). During the periods of low solar activity, they are insignificant. This work has been carried out with the support from International Scientific and Technology Center (Project #KR-214).

  17. Prognostic Value of Pulmonary Vascular Resistance by Magnetic Resonance in Systolic Heart Failure

    PubMed Central

    Fabregat-Andrés, Óscar; Estornell-Erill, Jordi; Ridocci-Soriano, Francisco; Pérez-Boscá, José Leandro; García-González, Pilar; Payá-Serrano, Rafael; Morell, Salvador; Cortijo, Julio

    2016-01-01

    Background Pulmonary hypertension is associated with poor prognosis in heart failure. However, non-invasive diagnosis is still challenging in clinical practice. Objective We sought to assess the prognostic utility of non-invasive estimation of pulmonary vascular resistances (PVR) by cardiovascular magnetic resonance to predict adverse cardiovascular outcomes in heart failure with reduced ejection fraction (HFrEF). Methods Prospective registry of patients with left ventricular ejection fraction (LVEF) < 40% and recently admitted for decompensated heart failure during three years. PVRwere calculated based on right ventricular ejection fraction and average velocity of the pulmonary artery estimated during cardiac magnetic resonance. Readmission for heart failure and all-cause mortality were considered as adverse events at follow-up. Results 105 patients (average LVEF 26.0 ±7.7%, ischemic etiology 43%) were included. Patients with adverse events at long-term follow-up had higher values of PVR (6.93 ± 1.9 vs. 4.6 ± 1.7estimated Wood Units (eWu), p < 0.001). In multivariate Cox regression analysis, PVR ≥ 5 eWu(cutoff value according to ROC curve) was independently associated with increased risk of adverse events at 9 months follow-up (HR2.98; 95% CI 1.12-7.88; p < 0.03). Conclusions In patients with HFrEF, the presence of PVR ≥ 5.0 Wu is associated with significantly worse clinical outcome at follow-up. Non-invasive estimation of PVR by cardiac magnetic resonance might be useful for risk stratification in HFrEF, irrespective of etiology, presence of late gadolinium enhancement or LVEF. PMID:26840055

  18. [Variations of solar activity and radiation situation on board MIR station during the period 1986-1994].

    PubMed

    Bondarenko, V A; Mitrikas, V G; Tsetlin , V V

    1995-01-01

    This paper is dedicated to the analysis of the radiation situation onboard Mir station over a period of 1986-1994, there examined the main cosmophysics parameters and indices of the solar activity as well as the variations of the parameters of the earth's magnetic field and their association with the changes in the power of absorbed dose onboard the station. There noted the high levels of radiation exposure to the cosmonauts under terrestrial conditions when carrying out the roentgeno-radiologic examinations and procedures comparable or exceeding the absorbed doses during the flights. For revealing the regular associations of the radiation situation onboard the station with the parameters of solar activity there has been analyzed the time changes of average monthly values of dose power since the beginning of station functioning in 1986 until returning the fifteenth expedition to Earth. From the analyses of the results it might be assumed that the best statistical associations of average monthly power of the absorbed dose are found with the streams of protons of GCR. Wolff numbers and background stream of the radio emission of the Sun which reflects the existence of the radiation situation upon the phase of solar activity cycle. From this paper it transpires that calculating the dose loads during the period of the extreme phases of solar activity, it is possible to make between them the interpolations of time dependence by analogy with the dynamics in time of the background streams of GCR or Wolff numbers.

  19. Dose received by occupationally exposed workers at a nuclear medicine department

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Avila, O.; Sanchez-Uribe, N. A.; Rodriguez-Laguna, A.

    2012-10-23

    Personal Dose Equivalent (PDE) values were determined for occupational exposed workers (OEW) at the Nuclear Medicine Department (NMD) of 'Instituto Nacional de Cancerologia' (INCan), Mexico, using TLD-100 thermoluminescent dosemeters. OEW at NMD, INCan make use of radiopharmaceuticals for diagnosis and treatment of diseases. Radionuclides associated to a pharmaceutical compound used at this Department are {sup 131}I, {sup 18}F, {sup 68}Ga, {sup 99m}Tc, {sup 111}In and {sup 11}C with main gamma emission energies between 140 and 511 keV. Dosemeter calibration was performed at the metrology department of 'Instituto Nacional de Investigaciones Nucleares' (ININ), Mexico. Every occupational worker used dark containers withmore » three dosimeters which were replaced monthly for a total of 5 periods. Additionally, control dosemeters were also placed at a site free of radioactive sources in order to determine the background radiation. Results were adjusted to find PDE/day and estimating annual PDE values in the range between 2 mSv (background) and 9 mSv. The mean annual value is 3.51 mSv and the standard deviation SD is 0.78 mSv. Four of the 16 OEW received annual doses higher than the average +1 SD (4.29 mSv). Results depend on OEW daily activities and were consistent for each OEW for the 5 studied periods as well as with PDE values reported by the firm that performs the monthly service. All obtained values are well within the established annual OEW dose limit stated in the {sup R}eglamento General de Seguridad Radiologica{sup ,} Mexico (50 mSv), as well as within the lower limit recommended by the 'International Commission on Radiation Protection' (ICRP), report no.60 (20 mSv). These results verify the adequate compliance of the NMD at INCan, Mexico with the norms given by the national regulatory commission.« less

  20. Tentative reference values for environmental pollutants in blood or urine from the children of Kinshasa.

    PubMed

    Tuakuila, J; Kabamba, M; Mata, H; Mbuyi, F

    2015-11-01

    The DRC, as most of African nations, does not have a national biomonitoring programme and there is a lack of information on background levels of environmental pollutants in the general DRC population, particularly in children. The focus of the data presented in this report aims to establish the background levels of a range of environmental pollutants in urine or blood from the children population of Kinshasa. Based on the representative data collection of the Kinshasa population, the survey selected 125 children aged 1-14years and living in Kinshasa (6years on average, 56% of girls, 100% of non-smokers, without amalgam fillings and consumers of fish 3 times per week). Biomarkers of a range of metals (As, Cd, Hg and Pb), pyrene (PAH) and benzene were analyzed in the blood or urine samples. Globally, the results indicate that the exposure levels of children living in Kinshasa are 10 times higher than those published by the American, Canadian and German children surveys. This study provides the first Reference Values of environmental pollutants [As, Cd, Hg, Pb, pyrene (PAH) and benzene] in the Kinshasa children population and reveals elevated levels of all biomarkers studied. The data set of this study may allow environmental and health authorities of DRC to undertake a national biomonitoring programme, especially with four insights for the protection of human heath. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Balloon-borne tropospheric CO2 observations over the equatorial eastern and western Pacific

    NASA Astrophysics Data System (ADS)

    Inai, Yoichi; Aoki, Shuji; Honda, Hideyuki; Furutani, Hiroshi; Matsumi, Yutaka; Ouchi, Mai; Sugawara, Satoshi; Hasebe, Fumio; Uematsu, Mitsuo; Fujiwara, Masatomo

    2018-07-01

    Vertical profiles of carbon dioxide (CO2) mixing ratio in the equatorial eastern and western Pacific were measured by newly developed balloon-borne CO2 sondes in February 2012 (two soundings) and February-March 2015 (four soundings), respectively. The 1-10 km vertically averaged CO2 mixing ratios lie between the background surface values in the Northern Hemisphere (NH) and those in the Southern Hemisphere (SH) monitored at ground-based sites during these periods. A backward trajectory analysis, taking account of convective mixing processes using geostationary satellite cloud-image data, is applied to the measured CO2 profiles to estimate the origin of the observed air masses. Air masses originating in the SH show low CO2 mixing ratios that are similar to the background values in the SH. This relationship is confirmed by a positive correlation (∼0.6) between the CO2 mixing ratio and the latitude of air mass origin which is found from trajectory calculations. This result suggests that the CO2 distribution in the troposphere over the equatorial Pacific is controlled by monthly time-scale, large-scale CO2 distribution and weekly time-scale atmospheric transport processes. Furthermore, this study shows that the combination of CO2 sonde measurements and trajectory analysis, taking account of convective mixing, is a useful tool in investigating CO2 transport processes.

  2. Investigation of the Relationship between Work Ability and Work-related Quality of Life in Nurses.

    PubMed

    Abbasi, Milad; Zakerian, Abolfazl; Akbarzade, Arash; Dinarvand, Nader; Ghaljahi, Maryam; Poursadeghiyan, Mohsen; Ebrahimi, Mohammad Hossein

    2017-10-01

    Work ability of nurses is an index of their job satisfaction and is a crucial factor in job quality and security. This study aimed to investigate the association between work ability and quality of working life and to determine the effective demographic and background variables, among nurses. The present study was conducted among nurses, working in educational hospitals under the supervision of Tehran University of Medical Sciences in 2014. Work Ability Index (WAI) and Work-related Quality of Life (WRQoL) were used. The mean WAI was significantly associated with total WRQoL score and the two of its sub-items including Stress at Work, and General Well-Being ( P -value=0.001). Moreover, the results showed a significant correlation between total WRQoL and WAI Subscales including mental resources ( P -value=0.001), number of current diseases ( P- value=0.02), and work ability in relation to the job demands ( P -value=0.04). The WRQoL and WAI showed significant associations with age and job experience ( P -value=0.001). The average score of WAI and WRQoL was statistically different among various working units ( P -value=0.001). Overall, results support the association between nurses work ability and WRQoL. Monitoring the WRQoL and work ability of employees would help organizations to know their status and take measures to ameliorate the working conditions.

  3. Estimating the urban bias of surface shelter temperatures using upper-air and satellite data. Part 2: Estimation of the urban bias

    NASA Technical Reports Server (NTRS)

    Epperson, David L.; Davis, Jerry M.; Bloomfield, Peter; Karl, Thomas R.; Mcnab, Alan L.; Gallo, Kevin P.

    1995-01-01

    A methodology is presented for estimating the urban bias of surface shelter temperatures due to the effect of the urban heat island. Multiple regression techniques were used to predict surface shelter temperatures based on the time period 1986-89 using upper-air data from the European Centre for Medium-Range Weather Forecasts (ECMWF) to represent the background climate, site-specific data to represent the local landscape, and satellite-derived data -- the normalized difference vegetation index (NDVI) and the Defense Meteorological Satellite Program (DMSP) nighttime brightness data -- to represent the urban and rural landscape. Local NDVI and DMSP values were calculated for each station using the mean NDVI and DMSP values from a 3 km x 3 km area centered over the given station. Regional NDVI and DMSP values were calculated to represent a typical rural value for each station using the mean NDVI and DMSP values from a 1 deg x 1 deg latitude-longitude area in which the given station was located. Models for the United States were then developed for monthly maximum, mean, and minimum temperatures using data from over 1000 stations in the U.S. Cooperative (COOP) Network and for monthly mean temperatures with data from over 1150 stations in the Global Historical Climate Network (GHCN). Local biases, or the differences between the model predictions using the observed NDVI and DMSP values, and the predictions using the background regional values were calculated and compared with the results of other research. The local or urban bias of U.S. temperatures, as derived from all U.S. stations (urban and rural) used in the models, averaged near 0.40 C for monthly minimum temperatures, near 0.25 C for monthly mean temperatures, and near 0.10 C for monthly maximum temperatures. The biases of monthly minimum temperatures for individual stations ranged from near -1.1 C for rural stations to 2.4 C for stations from the largest urban areas. The results of this study indicate minimal problems for global application once global NDVI and DMSP data become available.

  4. Study and Simulation on Dynamics of a Risk-Averse Supply Chain Pricing Model with Dual-Channel and Incomplete Information

    NASA Astrophysics Data System (ADS)

    Sun, Lijian; Ma, Junhai

    Under the industrial background of dual-channel, volatility in demand of consumers, we use the theory of bifurcations and numerical simulation tools to investigate the dynamic pricing game in a dual-channel supply chain with risk-averse behavior and incomplete information. Due to volatility of demand of consumers, we consider all the players in the supply chain are risk-averse. We assume there exist Bertrand game and Manufacturers’ Stackelberg in the chain which are closer to reality. The main objective of the paper is to investigate the complex influence of the decision parameters such as wholesale price adjustment speed, risk preference and service value on stability of the risk-averse supply chain and average utilities of all the players. We lay emphasis on the influence of chaos on average utilities of all the players which did not appear in previous studies. The dynamic phenomena, such as the bifurcation, chaos and sensitivity to initial values are analyzed by 2D bifurcation phase portraits, Double Largest Lyapunov exponent, basins of attraction and so on. The study shows that the manufacturers should slow down their wholesale price adjustment speed to get more utilities, if the manufacturers are willing to take on more risk, they will get more profits, but they must keep their wholesale prices in a certain range in order to maintain the market stability.

  5. Multi-objective optimization of MOSFETs channel widths and supply voltage in the proposed dual edge-triggered static D flip-flop with minimum average power and delay by using fuzzy non-dominated sorting genetic algorithm-II.

    PubMed

    Keivanian, Farshid; Mehrshad, Nasser; Bijari, Abolfazl

    2016-01-01

    D Flip-Flop as a digital circuit can be used as a timing element in many sophisticated circuits. Therefore the optimum performance with the lowest power consumption and acceptable delay time will be critical issue in electronics circuits. The newly proposed Dual-Edge Triggered Static D Flip-Flop circuit layout is defined as a multi-objective optimization problem. For this, an optimum fuzzy inference system with fuzzy rules is proposed to enhance the performance and convergence of non-dominated sorting Genetic Algorithm-II by adaptive control of the exploration and exploitation parameters. By using proposed Fuzzy NSGA-II algorithm, the more optimum values for MOSFET channel widths and power supply are discovered in search space than ordinary NSGA types. What is more, the design parameters involving NMOS and PMOS channel widths and power supply voltage and the performance parameters including average power consumption and propagation delay time are linked. To do this, the required mathematical backgrounds are presented in this study. The optimum values for the design parameters of MOSFETs channel widths and power supply are discovered. Based on them the power delay product quantity (PDP) is 6.32 PJ at 125 MHz Clock Frequency, L = 0.18 µm, and T = 27 °C.

  6. Investigation of micromixing by acoustically oscillated sharp-edges

    PubMed Central

    Nama, Nitesh; Huang, Po-Hsun; Huang, Tony Jun; Costanzo, Francesco

    2016-01-01

    Recently, acoustically oscillated sharp-edges have been utilized to achieve rapid and homogeneous mixing in microchannels. Here, we present a numerical model to investigate acoustic mixing inside a sharp-edge-based micromixer in the presence of a background flow. We extend our previously reported numerical model to include the mixing phenomena by using perturbation analysis and the Generalized Lagrangian Mean (GLM) theory in conjunction with the convection-diffusion equation. We divide the flow variables into zeroth-order, first-order, and second-order variables. This results in three sets of equations representing the background flow, acoustic response, and the time-averaged streaming flow, respectively. These equations are then solved successively to obtain the mean Lagrangian velocity which is combined with the convection-diffusion equation to predict the concentration profile. We validate our numerical model via a comparison of the numerical results with the experimentally obtained values of the mixing index for different flow rates. Further, we employ our model to study the effect of the applied input power and the background flow on the mixing performance of the sharp-edge-based micromixer. We also suggest potential design changes to the previously reported sharp-edge-based micromixer to improve its performance. Finally, we investigate the generation of a tunable concentration gradient by a linear arrangement of the sharp-edge structures inside the microchannel. PMID:27158292

  7. Investigation of micromixing by acoustically oscillated sharp-edges.

    PubMed

    Nama, Nitesh; Huang, Po-Hsun; Huang, Tony Jun; Costanzo, Francesco

    2016-03-01

    Recently, acoustically oscillated sharp-edges have been utilized to achieve rapid and homogeneous mixing in microchannels. Here, we present a numerical model to investigate acoustic mixing inside a sharp-edge-based micromixer in the presence of a background flow. We extend our previously reported numerical model to include the mixing phenomena by using perturbation analysis and the Generalized Lagrangian Mean (GLM) theory in conjunction with the convection-diffusion equation. We divide the flow variables into zeroth-order, first-order, and second-order variables. This results in three sets of equations representing the background flow, acoustic response, and the time-averaged streaming flow, respectively. These equations are then solved successively to obtain the mean Lagrangian velocity which is combined with the convection-diffusion equation to predict the concentration profile. We validate our numerical model via a comparison of the numerical results with the experimentally obtained values of the mixing index for different flow rates. Further, we employ our model to study the effect of the applied input power and the background flow on the mixing performance of the sharp-edge-based micromixer. We also suggest potential design changes to the previously reported sharp-edge-based micromixer to improve its performance. Finally, we investigate the generation of a tunable concentration gradient by a linear arrangement of the sharp-edge structures inside the microchannel.

  8. A plague on five of your houses - statistical re-assessment of three pneumonic plague outbreaks that occurred in Suffolk, England, between 1906 and 1918

    PubMed Central

    2010-01-01

    Background Plague is a re-emerging disease and its pneumonic form is a high priority bio-terrorist threat. Epidemiologists have previously analysed historical outbreaks of pneumonic plague to better understand the dynamics of infection, transmission and control. This study examines 3 relatively unknown outbreaks of pneumonic plague that occurred in Suffolk, England, during the first 2 decades of the twentieth century. Methods The Kolmogorov-Smirnov statistical test is used to compare the symptomatic period and the length of time between successive cases (i.e. the serial interval) with previously reported values. Consideration is also given to the case fatality ratio, the average number of secondary cases resulting from each primary case in the observed minor outbreaks (termed Rminor), and the proportion of individuals living within an affected household that succumb to pneumonic plague via the index case (i.e. the household secondary attack rate (SAR)). Results 2 of the 14 cases survived giving a case fatality ratio of 86% (95% confidence interval (CI) = {57%, 98%}). For the 12 fatal cases, the average symptomatic period was 3.3 days (standard deviation (SD) = 1.2 days) and, for the 11 non index cases, the average serial interval was 5.8 days (SD = 2.0 days). Rminor was calculated to be 0.9 (SD = 1.0) and, in 2 households, the SAR was approximately 14% (95% CI = {0%, 58%}) and 20% (95% CI = {1%, 72%}), respectively. Conclusions The symptomatic period was approximately 1 day longer on average than in an earlier study but the serial interval was in close agreement with 2 previously reported values. 2 of the 3 outbreaks ended without explicit public health interventions; however, non-professional caregivers were particularly vulnerable - an important public health consideration for any future outbreak of pneumonic plague. PMID:20973955

  9. Performance of the EDELWEISS-III experiment for direct dark matter searches

    NASA Astrophysics Data System (ADS)

    Armengaud, E.; Arnaud, Q.; Augier, C.; Benoît, A.; Bergé, L.; Bergmann, T.; Billard, J.; de Boissière, T.; Bres, G.; Broniatowski, A.; Brudanin, V.; Camus, P.; Cazes, A.; Chapellier, M.; Charlieux, F.; De Jésus, M.; Dumoulin, L.; Eitel, K.; Filosofov, D.; Foerster, N.; Fourches, N.; Garde, G.; Gascon, J.; Giuliani, A.; Grollier, M.; Gros, M.; Hehn, L.; Hervé, S.; Heuermann, G.; Humbert, V.; Jin, Y.; Juillard, A.; Kéfélian, C.; Kleifges, M.; Kozlov, V.; Kraus, H.; Kudryavtsev, V. A.; Le-Sueur, H.; Lin, J.; Maisonobe, R.; Mancuso, M.; Marnieros, S.; Menshikov, A.; Navick, X.-F.; Nones, C.; Olivieri, E.; Pari, P.; Paul, B.; Poda, D.; Queguiner, E.; Robinson, M.; Rodenas, H.; Rozov, S.; Sanglard, V.; Schmidt, B.; Scorza, S.; Siebenborn, B.; Tcherniakhovski, D.; Vagneron, L.; Weber, M.; Yakushev, E.; Zhang, X.; Zolotarova, A.

    2017-08-01

    We present the results of measurements demonstrating the efficiency of the EDELWEISS-III array of cryogenic germanium detectors for direct dark matter searches. The experimental setup and the FID (Fully Inter-Digitized) detector array is described, as well as the efficiency of the double measurement of heat and ionization signals in background rejection. For the whole set of 24 FID detectors used for coincidence studies, the baseline resolutions for the fiducial ionization energy are mainly below 0.7 keVee (FHWM) whereas the baseline resolutions for heat energies are mainly below 1.5 keVee (FWHM). The response to nuclear recoils as well as the very good discrimination capability of the FID design has been measured with an AmBe source. The surface β- and α-decay rejection power of Rsurf < 4 × 10-5 per α at 90% C.L. has been determined with a 210Pb source, the rejection of bulk γ-ray events has been demonstrated using γ-calibrations with 133Ba sources leading to a value of Rγ -mis-fid < 2.5 × 10-6 at 90% C.L.. The current levels of natural radioactivity measured in the detector array are shown as the rate of single γ background. The fiducial volume fraction of the FID detectors has been measured to a weighted average value of (74.6 ± 0.4)% using the cosmogenic activation of the 65Zn and 68,71Ge isotopes. The stability and uniformity of the detector response is also discussed. The achieved resolutions, thresholds and background levels of the upgraded EDELWEISS-III detectors in their setup are thus well suited to the direct search of WIMP dark matter over a large mass range.

  10. Monsoon-driven transport of atmospheric mercury to the South China Sea from the Chinese mainland and Southeast Asia-Observation of gaseous elemental mercury at a background station in South China.

    PubMed

    Liu, Ming; Chen, Laiguo; Xie, Donghai; Sun, Jiaren; He, Qiusheng; Cai, Limei; Gao, Zhiqiang; Zhang, Yiqiang

    2016-11-01

    Concentrations of gaseous elemental mercury (GEM) were continuously monitored from May 2011 to May 2012 at the Wuzhishan State Atmosphere Background Monitoring Station (109°29'30.2″ E, 18°50'11.0″ N) located in Hainan Island. This station is an ideal site for monitoring long-range transport of atmospheric pollutants from mainland China and Southeast Asia to South China Sea. Annual average GEM concentration was 1.58 ± 0.71 ng m -3 during the monitoring period, which was close to background values in the Northern Hemisphere. GEM concentrations showed a clear seasonal variation with relatively higher levels in autumn (1.86 ± 0.55 ng m -3 ) and winter (1.80 ± 0.62 ng m -3 ) and lower levels in spring (1.16 ± 0.45 ng m -3 ) and summer (1.43 ± 0.46 ng m -3 ). Long-range atmospheric transport dominated by monsoons was a dominant factor influencing the seasonal variations of GEM. The GEM diel trends were related to the wind speed and long-range atmospheric mercury transport. We observed 30 pollution episodes throughout the monitoring period. The analysis of wind direction and backward trajectory suggested that elevated GEM concentrations at the monitoring site were primarily related to the outflows of atmospheric Hg from mainland China and the Indochina peninsula. The △GEM/△CO values also suggested that GEM was significantly affected by the long-range transport from the anthropogenic sources and biomass burning in Asia and Indochina peninsula.

  11. Star formation history from the cosmic infrared background anisotropies

    NASA Astrophysics Data System (ADS)

    Maniyar, A. S.; Béthermin, M.; Lagache, G.

    2018-06-01

    We present a linear clustering model of cosmic infrared background (CIB) anisotropies at large scales that is used to measure the cosmic star formation rate density up to redshift 6, the effective bias of the CIB, and the mass of dark matter halos hosting dusty star-forming galaxies. This is achieved using the Planck CIB auto- and cross-power spectra (between different frequencies) and CIB × CMB (cosmic microwave background) lensing cross-spectra measurements, as well as external constraints (e.g. on the CIB mean brightness). We recovered an obscured star formation history which agrees well with the values derived from infrared deep surveys and we confirm that the obscured star formation dominates the unobscured formation up to at least z = 4. The obscured and unobscured star formation rate densities are compatible at 1σ at z = 5. We also determined the evolution of the effective bias of the galaxies emitting the CIB and found a rapid increase from 0.8 at z = 0 to 8 at z = 4. At 2 < z < 4, this effective bias is similar to that of galaxies at the knee of the mass functions and submillimetre galaxies. This effective bias is the weighted average of the true bias with the corresponding emissivity of the galaxies. The halo mass corresponding to this bias is thus not exactly the mass contributing the most to the star formation density. Correcting for this, we obtained a value of log(Mh/M⊙) = 12.77-0.125+0.128 for the mass of the typical dark matter halo contributing to the CIB at z = 2. Finally, using a Fisher matrix analysis we also computed how the uncertainties on the cosmological parameters affect the recovered CIB model parameters, and find that the effect is negligible.

  12. CALIPSO Detection of an Asian Tropopause Aerosol Layer

    NASA Technical Reports Server (NTRS)

    Vemier, J.-P.; Thomason, L. W.; Kar, J.

    2011-01-01

    The first four years of the CALIPSO lidar measurements have revealed the existence of an aerosol layer at the tropopause level associated with the Asian monsoon season in June, July and August. This Asian Tropopause Aerosol Layer (ATAL) extends geographically from Eastern Mediterranean (down to North Africa) to Western China (down to Thailand), and vertically from 13 to 18 km. The Scattering Ratio inferred from CALIPSO shows values between 1.10. 1.15 on average with associated depolarization ratio of less than 5%. The Gaussian distribution of the points indicates that the mean value is statistically driven by an enhancement of the background aerosol level and not by episodic events such as a volcanic eruption or cloud contamination. Further satellite observations of aerosols and gases as well as field campaigns are urgently needed to characterize this layer, which is likely to be a significant source of non-volcanic aerosols for the global upper troposphere with a potential impact on its radiative and chemical balance

  13. THERMOLUMINESCENT DOSIMETRY IN THE EVALUATION OF NATURAL RADIOACTIVITY INDOOR OF HOMES NEAR THE URANIUM DEPOSIT OF PARAÍBA, BRAZIL.

    PubMed

    Bezerra, Jairo Dias; Dos Santos Júnior, José Araújo; Dos Santos Amaral, Romilton; Menezes, Rômulo Simões Cezar; Fernández, Zahily Herrero; do Nascimento Santos, Josineide Marques; da Silva, Arykerne Nascimento Casado; Rojas, Lino Angel Valcárcel

    2018-06-01

    High levels of primordial radionuclides have been reported in soils and rocks of São José de Espinharas, in the state of Paraiba, Brazil. These radionuclides are derived from high concentrations of natural uranium and thorium from a mine in the region. Thus, there is a need for a dosimetric evaluation in the area near the mine and the surrounding cities. In this study, the annual effective dose was analyzed in 178 points of five cities. The measurements were performed using thermoluminescent dosimetry with LiF:Mg, Ti (TLD-100). The annual effective dose from environmental exposure varied from 0.71 to 2.07 mSv, with an arithmetic mean of 0.99 mSv. This average is more than twice the estimated value for indoor environments adopted by the UNSCEAR, which is 0.41 mSv. These results will allow establishing reference values for background radiation of the region and criteria to infer a stochastic risk for the local population.

  14. Human absorption and retention of polonium-210 from caribou meat.

    PubMed

    Thomas, P A; Fisenne, I; Chorney, D; Baweja, A S; Tracy, B L

    2001-01-01

    The gastrointestinal (GI) absorption factors and the biological retention times for polonium were determined for a group of 14 volunteers--seven men and seven women--from Saskatoon, Saskatchewan, Canada. Each volunteer consumed 2.0 kg of caribou meat containing known amounts of naturally occurring 210Po. Urine and faecal samples were collected for up to 65 days after meat consumption and analysed for 210Po. The average GI absorption factor for the 14 volunteers was 56 +/- 4% (range = 31-71%), not significantly different from the ICRP value of 50%. About 3% of absorbed polonium underwent prompt excretion by the urinary pathway. The remainder was retained by the body with a half-time >100 days, compared to the ICRP value of 50 days. The effect of these findings increases the dose estimate for ingestion of 210Po in food by a factor of 1.5 to 3.5. Thus, background doses to people consuming caribou and reindeer may be higher than previously thought.

  15. Observations of hydrogen and helium isotopes in solar cosmic rays. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Hurford, G. J.

    1974-01-01

    The isotopic composition of hydrogen and helium in solar cosmic rays provides a means of studying solar flare particle acceleration mechanisms since the enhanced relative abundance of rare isotopes, such as H-2, H-3, and He-3, is due to their production by inelastic nuclear collisions in the solar atmosphere during the flare. Electron isotope spectrometer on an IMP spacecraft was used to measure this isotopic composition. The response of the dE/dx-E particle telescope is discussed, and alpha particle channeling in thin detectors is identified as an important background source affecting measurement of low values of (He-3/He-4). The flare-averaged results obtained for the period October, 1972 November, 1973 are given.

  16. Validating Satellite-Derived Land Surface Temperature with in Situ Measurements: A Public Health Perspective

    PubMed Central

    Brines, Shannon J.; Brown, Daniel G.; Dvonch, J. Timothy; Gronlund, Carina J.; Zhang, Kai; Oswald, Evan M.; O’Neill, Marie S.

    2013-01-01

    Background: Land surface temperature (LST) and percent surface imperviousness (SI), both derived from satellite imagery, have been used to characterize the urban heat island effect, a phenomenon in which urban areas are warmer than non-urban areas. Objectives: We aimed to assess the correlations between LSTs and SI images with actual temperature readings from a ground-based network of outdoor monitors. Methods: We evaluated the relationships among a) LST calculated from a 2009 summertime satellite image of the Detroit metropolitan region, Michigan; b) SI from the 2006 National Land Cover Data Set; and c) ground-based temperature measurements monitored during the same time period at 19 residences throughout the Detroit metropolitan region. Associations between these ground-based temperatures and the average LSTs and SI at different radii around the point of the ground-based temperature measurement were evaluated at different time intervals. Spearman correlation coefficients and corresponding p-values were calculated. Results: Satellite-derived LST and SI values were significantly correlated with 24-hr average and August monthly average ground temperatures at all but two of the radii examined (100 m for LST and 0 m for SI). Correlations were also significant for temperatures measured between 0400 and 0500 hours for SI, except at 0 m, but not LST. Statistically significant correlations ranging from 0.49 to 0.91 were observed between LST and SI. Conclusions: Both SI and LST could be used to better understand spatial variation in heat exposures over longer time frames but are less useful for estimating shorter-term, actual temperature exposures, which can be useful for public health preparedness during extreme heat events. PMID:23777856

  17. Mercury Levels in Pregnant Women, Children, and Seafood from Mexico City

    PubMed Central

    Basu, Niladri; Tutino, Rebecca; Zhang, Zhenzhen; Cantonwine, David E.; Goodrich, Jaclyn M.; Somers, Emily C.; Rodriguez, Lauren; Schnaas, Lourdes; Solano, Maritsa; Mercado, Adriana; Peterson, Karen; Sánchez, Brisa N.; Hernández-Avila, Mauricio; Hu, Howard; Téllez-Rojo, Martha Maria

    2014-01-01

    Background Mercury is a global contaminant of concern though little is known about exposures in México. Objectives To characterize mercury levels in pregnant women, children, and commonly consumed seafood samples. Methods Use resources of the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) birth cohorts to measure total mercury levels in archived samples from 348 pregnant women (blood from three trimesters and cord blood), 825 offspring (blood, hair, urine) and their mothers (hair), and 91 seafood and canned tuna samples from Mexico City. Results Maternal blood mercury levels correlated across three trimesters and averaged 3.4μg/L. Cord blood mercury averaged 4.7μg/L and correlated with maternal blood from trimester 3 (but not trimesters 1 and 2). In children, blood, hair and urine mercury levels correlated and averaged 1.8μg/L, 0.6μg/g, and 0.9μg/L, respectively. Hair mercury was 0.5μg/g in mothers and correlated with child's hair. Mean consumption of canned tuna, fresh fish, canned sardine, and shellfish was 3.1, 2.2, 0.5, and 1.0 times per month respectively in pregnant women. Mean mercury content in 7 of 23 seafood species and 5 of 9 canned tuna brands purchased exceeded the U.S. EPA guidance value of 0.3 μg/g. Conclusions Mercury exposures in pregnant women and children from Mexico City, via biomarker studies, are generally 3-5 times greater than values reported in population surveys from the U.S., Canada, and elsewhere. In particular, mercury levels in 29-39% of the maternal participants exceeded the biomonitoring guideline associated with the U.S. EPA reference dose for mercury. PMID:25262076

  18. The nature of Mesoarchaean seawater and continental weathering in 2.85 Ga banded iron formation, Slave craton, NW Canada

    NASA Astrophysics Data System (ADS)

    Haugaard, Rasmus; Ootes, Luke; Creaser, Robert A.; Konhauser, Kurt O.

    2016-12-01

    Banded iron formations (BIF) have been extensively used as proxies to infer the chemical composition of ancient bulk seawater. However, their proximity to ancient crust suggests that they might also be used to reveal the composition of emergent continental landmass at the time of their deposition. Here we use the combination of geochemistry and Sm-Nd isotopes on a layer-by-layer basis to interpret the relative contributions of hydrothermal, hydrogenous and terrestrial input to one of the oldest documented Superior-type BIF in the world. The ∼2.85 Ga Central Slave Cover Group BIF is deposited within a rift basin related to a continental margin and is found associated with basement gneisses, as well as shoreline and shallow-shelf type facies, such as fuchsitic quartzite and pebble-to-cobble conglomerate, that confirm a near-shore depositional setting for the BIF. The BIF ranges from a pure chemical oxide (magnetite)-silicate (grunerite + actinolite) sediment with low Al2O3 (<1 wt.%) into a mixture of chemical and clastic sediment characterized by higher Al2O3 (⩽10 wt.%) and the occurrence of ferro-hornblende, biotite and garnet. The silica bands have low trace metal content (e.g., Ni), low ∑REE (average of 6 ppm) and a shale-normalized rare earth and yttrium (REY) pattern that is HREE-to-LREE enriched with (Pr/Yb)SN values reaching <0.2. The iron bands are more enriched, with average ∑REE of 26 and with a more uniform and less fractionated REY pattern (average (Pr/Yb)SN of 0.5). During active rifting of the basement, excess of Eu2+ impacted the basin yielding seawater with Eu anomalies [(Eu/Eu∗)SN] as high as 3.85 (average 2.75), larger than similarly-aged BIF. High-resolution geochemistry shows that there is more silica (19.4 wt.% SiO2) in the iron bands than iron (8.7 wt.% Fe2O3) in the silica bands, implying that dissolved Fe2+ came to the BIF site in pulses and that silica likely represents background deposition. Consistently radiogenic εNd(t) values for the iron bands (average +1.7) show that the dissolved REY in the source water during ferric iron precipitation was provided by submarine hydrothermal fluids with relatively uniform 143Nd/144Nd. The silica bands, by contrast, reveal high variation in seawater 143Nd/144Nd as evident from the bimodal εNd(t) distribution with one segment exhibiting negative εNd(t) values averaging -1.1 and another with positive εNd(t) values averaging +2.5. This suggests input of dissolved REY into the upper seawater from weathering of isotopically different crustal components in the source region. Collectively, we speculate that the low REY in the upper seawater and the overall low Ni content implies a highly weathered crustal surface that was unable to contribute a significant dissolved load to the shelf environment.

  19. The Asymptotic Safety Scenario in Quantum Gravity.

    PubMed

    Niedermaier, Max; Reuter, Martin

    2006-01-01

    The asymptotic safety scenario in quantum gravity is reviewed, according to which a renormalizable quantum theory of the gravitational field is feasible which reconciles asymptotically safe couplings with unitarity. The evidence from symmetry truncations and from the truncated flow of the effective average action is presented in detail. A dimensional reduction phenomenon for the residual interactions in the extreme ultraviolet links both results. For practical reasons the background effective action is used as the central object in the quantum theory. In terms of it criteria for a continuum limit are formulated and the notion of a background geometry self-consistently determined by the quantum dynamics is presented. Self-contained appendices provide prerequisites on the background effective action, the effective average action, and their respective renormalization flows.

  20. Disparities between Ophthalmologists and Patients in Estimating Quality of Life Associated with Diabetic Retinopathy

    PubMed Central

    Zou, Haidong; Xu, Xun; Zhang, Xi

    2015-01-01

    Background This study aimed to evaluate and compare the utility values associated with diabetic retinopathy (DR) in a sample of Chinese patients and ophthalmologists. Methods Utility values were evaluated by both the time trade-off (TTO) and rating scale (RS) methods for 109 eligible patients with DR and 2 experienced ophthalmologists. Patients were stratified by Snellen best-corrected visual acuity (BCVA) in the better-seeing eye. The correlations between the utility values and general vision-related health status measures were analyzed. These utility values were compared with data from two other studies. Results The mean utility values elicited from the patients themselves with the TTO (0.81; SD 0.10) and RS (0.81; SD 0.11) methods were both statistically lower than the mean utility values assessed by ophthalmologists. Significant predictors of patients’ TTO and RS utility values were both LogMAR BCVA in the affected eye and average weighted LogMAR BCVA. DR grade and duration of visual dysfunction were also variables that significantly predicted patients’ TTO utility values. For ophthalmologists, patients’ LogMAR BCVA in the affected eye and in the better eye were the variables that significantly predicted both the TTO and RS utility values. Patients’ education level was also a variable that significantly predicted RS utility values. Moreover, both diabetic macular edema and employment status were significant predictors of TTO and RS utility values, whether from patients or ophthalmologists. There was no difference in mean TTO utility values compared to our American and Canadian patients. Conclusions DR caused a substantial decrease in Chinese patients’ utility values, and ophthalmologists substantially underestimated its effect on patient quality of life. PMID:26630653

  1. Guide for SDEC Set up

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bibby, R; Guthrie, E

    2009-01-30

    The instrument has four collection vials that must be filled with ethylene glycol before operation. Each of the four vials should be labeled 1 through 4 and the empty weights recorded. Fill each vial with 80 mL of ethylene glycol and record the weight again. In order for the instrument to operate properly, the collection vials should always have less than 160 mL of total liquid in them. After completing a sample run, remove the collection vials, use a transfer pipette to remove any liquid that might still be on the air paddler, wipe off any condensation from the exteriormore » of the collection vial and record weight. From the instrument, record the ending volume and the time of operation. The solution mixed in the scintillation vial will be 2 ml of a 95% to 50% ethylene glycol to water mixture. To determine the efficiency of counting at all of these concentrations, a series of vials should be set up that consist of 18 ml of Ultima Gold LLT cocktail mixed with standard, regular deionized water and ethylene glycol. The efficiency curve should be counted in the 'Low Level' count mode with the Luminescence Correction ON and the Color Quench Correction ON. Once the tSIE values are determined, chart the cpm against the tSIE numbers and find the best fit for the data. The resulting equation is to be used to converting tSIE values from the collection vials to efficiency. To determine the background cpm value of the ethylene glycol, count a 2 ml sample of ethylene glycol with 18 ml of Ultima Gold for 100 minutes. To determine the total activity of the sample, take two 2 ml aliquots of sample from the first vial and place in separate scintillation vials. Record the weight of each aliquot. Determine the percentage of total sample each aliquot represents by dividing the aliquot weight by the total solution weight from the vial. Also, determine the percentage of ethylene glycol in the sample by dividing the initial solution weight by the final solution weight and multiplying by 100. Add 18 ml of Ultima Gold to each vial and proceed to count for 100 minutes in a 'Low Level' count mode. Before performing a calculation on the dpm value of each aliquot, a subtraction should be made for the background count rate of the ethylene glycol. Based on the background cpm, multiply the background cpm value by the percentage of ethylene glycol in the collection vial. Once the background value is subtracted, calculate the dpm value of the sample based on the tSIE conversion to efficiency. This will produce a dpm value. To convert this to a total activity of the sample, divide the aliquot dpm value by the decimal percentage of total sample the aliquot represents. This gives the total activity of the sample solution. Take the average of both aliquots as a final result. To convert the total activity from the solution in vial one to activity in air, an empirical formula is used to convert activity/gram from vial one to total activity introduced into the system. After calculation the final result for the vial, divide the total by the mass of the sample in vial one. This gives dpm/g (labeled C{sub m}). To convert this to total dpm measured, C = (128.59 * Cm + 10.837)/V Where: C = Tritium concentration in air (dpm/m{sup 3}) C{sub m} = measured tritium concentration from vial 1 (dpm/g) V = Volume of air sampled through instrument (m{sup 3}). C is the final value of tritium concentration in air.« less

  2. FIRST-ORDER COSMOLOGICAL PERTURBATIONS ENGENDERED BY POINT-LIKE MASSES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eingorn, Maxim, E-mail: maxim.eingorn@gmail.com

    2016-07-10

    In the framework of the concordance cosmological model, the first-order scalar and vector perturbations of the homogeneous background are derived in the weak gravitational field limit without any supplementary approximations. The sources of these perturbations (inhomogeneities) are presented in the discrete form of a system of separate point-like gravitating masses. The expressions found for the metric corrections are valid at all (sub-horizon and super-horizon) scales and converge at all points except at the locations of the sources. The average values of these metric corrections are zero (thus, first-order backreaction effects are absent). Both the Minkowski background limit and the Newtonianmore » cosmological approximation are reached under certain well-defined conditions. An important feature of the velocity-independent part of the scalar perturbation is revealed: up to an additive constant, this part represents a sum of Yukawa potentials produced by inhomogeneities with the same finite time-dependent Yukawa interaction range. The suggested connection between this range and the homogeneity scale is briefly discussed along with other possible physical implications.« less

  3. Rodent carcinogens: Setting priorities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gold, L.S.; Slone, T.H.; Stern, B.R.

    1992-10-09

    The human diet contains an enormous background of natural chemicals, such as plant pesticides and the products of cooking, that have not been a focus of carcinogenicity testing. A broadened perspective that includes these natural chemicals is necessary. A comparison of possible hazards for 80 daily exposures to rodent carcinogens from a variety of sources is presented, using an index (HERP) that relates human exposure to carcinogenic potency in rodents. A similar ordering would be expected with the use of standard risk assessment methodology for the same human exposure values. Results indicate that, when viewed against the large background ofmore » naturally occurring carcinogens in typical portions of common foods, the residues of synthetic pesticides or environmental pollutants rank low. A similar result is obtained in a separate comparison of 32 average daily exposures to natural pesticides and synthetic pesticides residues in the diet. Although the findings do not indicate that these natural dietary carcinogens are important in human cancer, they cast doubt on the relative importance for human cancer of low-dose exposures to synthetic chemicals.« less

  4. Analysis of the solar radiation data for Beer Sheva, Israel, and its environs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kudish, A.I.; Ianetz, A.

    The solar radiation climate of Beer Sheva, Israel, is reported upon in detail. The database utilized in this analysis consisted of global radiation on a horizontal surface, normal incidence beam radiation, and global radiation on a south-facing surface tilted at 40{degree}. Monthly-average hourly and daily values are reported for each of these three types of measured radiations, together with the calculated monthly-average daily values for the components of the global radiation, viz. the horizontal beam and diffuse radiations. The monthly-average hourly and daily clearness index values have also been calculated and analyzed. Monthly-average daily frequency distributions of the clearness indexmore » values are reported for each month. The solar radiation climate of Beer Sheva has also been compared to those reported for a number of countries in this region. The annual-average daily global radiation incident on a horizontal surface is 18.91 MG/m{sup 2} and that for normal incidence beam radiation is 21.17 MG/m{sup 2}. The annual-average daily fraction of the horizontal global radiation that is beam is 0.72. The annual-average daily value for the clearness index is 0.587 and the average frequency of clear days annually is 58.6%. The authors conclude, based upon the above analysis, that Beer Sheva and its environs are characterized by relatively high, average-daily irradiation rates, both global and beam, and a relatively high frequency of clear days.« less

  5. Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns (CXIDB ID 9)

    DOE Data Explorer

    Loh, Ne-Te Duane

    2011-08-01

    These 2000 single-shot diffraction patterns include were either background-scattering only or hits (background-scattering plus diffraction signal from sub-micron ellipsoidal particles at random, undetermined orientations). Candidate hits were identified by eye, and the remainder were presumed as background. 54 usable, background-subtracted hits in this set (procedure in referenced article) were used to reconstruct the 3D diffraction intensities of the average ellipsoidal particle.

  6. Some induced intuitionistic fuzzy aggregation operators applied to multi-attribute group decision making

    NASA Astrophysics Data System (ADS)

    Su, Zhi-xin; Xia, Guo-ping; Chen, Ming-yuan

    2011-11-01

    In this paper, we define various induced intuitionistic fuzzy aggregation operators, including induced intuitionistic fuzzy ordered weighted averaging (OWA) operator, induced intuitionistic fuzzy hybrid averaging (I-IFHA) operator, induced interval-valued intuitionistic fuzzy OWA operator, and induced interval-valued intuitionistic fuzzy hybrid averaging (I-IIFHA) operator. We also establish various properties of these operators. And then, an approach based on I-IFHA operator and intuitionistic fuzzy weighted averaging (WA) operator is developed to solve multi-attribute group decision-making (MAGDM) problems. In such problems, attribute weights and the decision makers' (DMs') weights are real numbers and attribute values provided by the DMs are intuitionistic fuzzy numbers (IFNs), and an approach based on I-IIFHA operator and interval-valued intuitionistic fuzzy WA operator is developed to solve MAGDM problems where the attribute values provided by the DMs are interval-valued IFNs. Furthermore, induced intuitionistic fuzzy hybrid geometric operator and induced interval-valued intuitionistic fuzzy hybrid geometric operator are proposed. Finally, a numerical example is presented to illustrate the developed approaches.

  7. Affirming Independence: Exploring Mechanisms Underlying a Values Affirmation Intervention for First-Generation Students

    PubMed Central

    Tibbetts, Yoi; Harackiewicz, Judith M.; Canning, Elizabeth A.; Boston, Jilana S.; Priniski, Stacy J.; Hyde, Janet S.

    2016-01-01

    First-generation college students (students for whom neither parent has a 4-year college degree) earn lower grades and worry more about whether they belong in college, compared to continuing-generation students (who have at least one parent with a 4-year college degree). We conducted a longitudinal follow-up of participants from a study in which a values-affirmation intervention improved performance in a biology course for first-generation college students, and found that the treatment effect on grades persisted three years later. First-generation students in the treatment condition obtained a GPA that was, on average, .18 points higher than first-generation students in the control condition, three years after values affirmation was implemented (Study 1A). We explored mechanisms by testing if the values-affirmation effects were predicated on first-generation students reflecting on interdependent values (thus affirming their values that are consistent with working-class culture) or independent values (thus affirming their values that are consistent with the culture of higher education). We found that when first-generation students wrote about their independence, they obtained higher grades (both in the semester in which values affirmation was implemented and in subsequent semesters) and felt less concerned about their background. In a separate laboratory experiment (Study 2) we manipulated the extent to which participants wrote about independence and found that encouraging first-generation students to write more about their independence improved their performance on a math test. These studies highlight the potential of having FG students focus on their own independence. PMID:27176770

  8. Quantitative assessment of local perfusion change in acute intracerebral hemorrhage areas with and without "dynamic spot sign" using CT perfusion imaging.

    PubMed

    Fu, Fan; Sui, Binbin; Liu, Liping; Su, Yaping; Sun, Shengjun; Li, Yingying

    2018-01-01

    Background Positive "dynamic spot sign" has been proven to be a potential risk factor for acute intracerebral hemorrhage (ICH) expansion, but local perfusion change has not been quantitatively investigated. Purpose To quantitatively evaluate perfusion changes at the ICH area using computed tomography perfusion (CTP) imaging. Material and Methods Fifty-three patients with spontaneous ICH were recruited. Unenhanced computed tomography (NCCT), CTP within 6 h, and follow-up NCCT were performed for 21 patients in the "spot sign"-positive group and 32 patients in the control group. Cerebral perfusion change was quantitatively measured on regional cerebral blood flow/regional cerebral blood volume (rCBF/rCBV) maps. Regions of interest (ROIs) were set at the "spot-sign" region and the whole hematoma area for "spot-sign"-positive cases, and at one of the highest values of three interested areas and the whole hematoma area for the control group. Hematoma expansion was determined by follow-up NCCT. Results For the "spot-sign"-positive group, the average rCBF (rCBV) values at the "spot-sign" region and the whole hematoma area were 21.34 ± 15.24 mL/min/100 g (21.64 ± 21.48 mL/100g) and 5.78 ± 6.32 mL/min/100 g (6.07 ± 5.45 mL/100g); for the control group, the average rCBF (rCBV) values at the interested area and whole hematoma area were 2.50 ± 1.83 mL/min/100 g (3.13 ± 1.96 mL/100g) and 3.02 ± 1.80 mL/min/100 g (3.40 ± 1.44 mL/100g), respectively. Average rCBF and rCBV values of the "spot-sign" region were significantly different from other regions ( P < 0.001; P = 0.004). The average volumes of hematoma expansion in the "spot-sign"-positive and control groups were 25.24 ± 19.38 mL and -0.41 ± 1.34 mL, respectively. Conclusion The higher perfusion change at ICH on CTP images may reflect the contrast extravasation and be associated with the hematoma expansion.

  9. Temporal variability of benzene concentration in the ambient air of Delhi: a comparative assessment of pre- and post-CNG periods.

    PubMed

    Khillare, P S; Hoque, Raza Rafiqul; Shridhar, Vijay; Agarwal, Tripti; Balachandran, S

    2008-06-15

    CNG (compressed natural gas) was fully implemented in public transport system in Delhi in December 2002. The study assesses the benzene concentration trends at two busy traffic intersections and a background site in Delhi, India. Monitoring was done for two different time periods viz; in the year 2001-2002 (pre-CNG) and two winter months (January and February) of the year 2007 (post-CNG) to assess the impact of various policy measures adopted by the government of Delhi to improve the air quality in the city. Annual average benzene concentration for the pre-CNG period was found to be 86.47+/-53.24 microg m(-3). Average benzene concentrations for the winter months (January-February) of pre- and post-CNG periods were 116.32+/-51.65 microg m(-3) and 187.49+/-22.50 microg m(-3), respectively. Enhanced values could be solely attributed to the increase in the vehicular population from 3.5 million in the year 2001-2002 to approximately 5.1 millions in the year 2007.

  10. Lack of reliability of nanotechnology in the of free plasma DNA in samples of patients with prostate cancer

    PubMed Central

    2013-01-01

    Background Several studies seek biological markers that give diagnostic and degree of tumor development. The aim of this study was to validate the determination of plasma DNA using nanotechnology (Nanovue™-NV) in samples of 80 patients with prostate cancer. Methods Blood samples of 80 patients of the Urology Ambulatory of Faculdade de Medicina do ABC with prostate cancer confirmed by anatomical-pathology criteria were analyzed. DNA extraction was performed using a GFX TM kit (Amersham Pharmacia Biotech, Inc, USA) following the adapted protocol. Plasma was subjected to centrifugation. Results There was a big difference between the first and the second value obtained by NanoVue Only two samples had no differences between duplicates. Maximum difference between duplicates was 38 μg/mL. Average variation between 51 samples was 10.29 μg/mL, although 21 samples had differences above this average. No correlation was observed between pDNA obtained by traditional spectrophotometry and by nanotechnology. Conclusion Determination of plasma DNA by nanotechnology was not reproducible. PMID:23311763

  11. Incremental Value of Repeated Risk Factor Measurements for Cardiovascular Disease Prediction in Middle-Aged Korean Adults: Results From the NHIS-HEALS (National Health Insurance System-National Health Screening Cohort).

    PubMed

    Cho, In-Jeong; Sung, Ji Min; Chang, Hyuk-Jae; Chung, Namsik; Kim, Hyeon Chang

    2017-11-01

    Increasing evidence suggests that repeatedly measured cardiovascular disease (CVD) risk factors may have an additive predictive value compared with single measured levels. Thus, we evaluated the incremental predictive value of incorporating periodic health screening data for CVD prediction in a large nationwide cohort with periodic health screening tests. A total of 467 708 persons aged 40 to 79 years and free from CVD were randomly divided into development (70%) and validation subcohorts (30%). We developed 3 different CVD prediction models: a single measure model using single time point screening data; a longitudinal average model using average risk factor values from periodic screening data; and a longitudinal summary model using average values and the variability of risk factors. The development subcohort included 327 396 persons who had 3.2 health screenings on average and 25 765 cases of CVD over 12 years. The C statistics (95% confidence interval [CI]) for the single measure, longitudinal average, and longitudinal summary models were 0.690 (95% CI, 0.682-0.698), 0.695 (95% CI, 0.687-0.703), and 0.752 (95% CI, 0.744-0.760) in men and 0.732 (95% CI, 0.722-0.742), 0.735 (95% CI, 0.725-0.745), and 0.790 (95% CI, 0.780-0.800) in women, respectively. The net reclassification index from the single measure model to the longitudinal average model was 1.78% in men and 1.33% in women, and the index from the longitudinal average model to the longitudinal summary model was 32.71% in men and 34.98% in women. Using averages of repeatedly measured risk factor values modestly improves CVD predictability compared with single measurement values. Incorporating the average and variability information of repeated measurements can lead to great improvements in disease prediction. URL: https://www.clinicaltrials.gov. Unique identifier: NCT02931500. © 2017 American Heart Association, Inc.

  12. The effects of social concern goals on the value of learning and on the intentions of medical students to change their majors

    PubMed Central

    Park, Soowon; Cho, Seunghee; Lee, Jun-Young

    2017-01-01

    ABSTRACT Background: In the process of developing a professional medical expertise, goals can become a psychological impetus and act as a source of retaining an individual’s persistency. Therefore, the goals of medical students should be considered when designing a curriculum for health professions. Purpose: The purpose of this study was to examine relative effects of goal categories on the value of learning and intention to change one’s major. Method: Data were obtained from the Korea Education Longitudinal Study, which included 1938 representative Korean college freshmen majoring in medicine, engineering, natural science and humanities. They answered a survey questionnaire about goal categories (i.e., social concern, affiliation, self-growth, leisure, wealth, and fame), the value of learning, and intention to change one's major. Results: For medical students, social concern goals were positively related to the value of learning and negatively related to the intention to change one's major. Social concern goals decreased the intention to change one's major directly, and also indirectly through increased value of learning. Conclusion: Providing context for enhancing medical students’ social concern goals is necessary in a medical training curriculum, not only for the students’ professional development but also for improving society. Abbreviations: GCT: Goal contents theory GPA: Grade point average KELS: Korea education longitudinal study SDLA: Self-directed learning abilities SDT: Self-determination theory PMID:28580860

  13. Air-surface exchange measurements of gaseous elemental mercury over naturally enriched and background terrestrial landscapes in Australia

    NASA Astrophysics Data System (ADS)

    Edwards, G. C.; Howard, D. A.

    2013-05-01

    This paper presents the first gaseous elemental mercury (GEM) air-surface exchange measurements obtained over naturally enriched and background (<0.1 μg g-1 Hg) terrestrial landscapes in Australia. Two pilot field studies were carried out during the Australian autumn and winter periods at a copper-gold-cobalt-arsenic-mercury mineral field near Pulganbar, NSW. GEM fluxes using a dynamic flux chamber approach were measured, along with controlling environmental parameters over three naturally enriched and three background substrates. The enriched sites results showed net emission to the atmosphere and a strong correlation between flux and substrate Hg concentration, with average fluxes ranging from 14 ± 1 ng m-2 h-1 to 113 ± 6 ng m-2 h-1. Measurements at background sites showed both emission and deposition. The average Hg flux from all background sites showed an overall net emission of 0.36 ± 0.06 ng m-2 h-1. Fluxes show strong relationships with temperature, radiation, and substrate parameters. A compensation point of 2.48, representative of bare soils was determined. For periods of deposition, dry deposition velocities ranged from 0.00025 cm s-1 to 0.0083 cm s-1 with an average of 0.0041 ± 0.00018 cm s-1, representing bare soil, nighttime conditions. Comparison of the Australian data to North American data suggests the need for Australian-specific mercury air-surface exchange data representative of Australia's unique climatic conditions, vegetation types, land use patterns and soils.

  14. Seasonal atmospheric deposition variations of polychlorinated biphenyls (PCBs) and comparison of some deposition sampling techniques.

    PubMed

    Birgül, Askın; Tasdemir, Yücel

    2011-03-01

    Ambient air and bulk deposition samples were collected between June 2008 and June 2009. Eighty-three polychlorinated biphenyl (PCB) congeners were targeted in the samples. The average gas and particle PCB concentrations were found as 393 ± 278 and 70 ± 102 pg/m(3), respectively, and 85% of the atmospheric PCBs were in the gas phase. Bulk deposition samples were collected by using a sampler made of stainless steel. The average PCB bulk deposition flux value was determined as 6,020 ± 4,350 pg/m(2) day. The seasonal bulk deposition fluxes were not statistically different from each other, but the summer flux had higher values. Flux values differed depending on the precipitation levels. The average flux value in the rainy periods was 7,480 ± 4,080 pg/m(2) day while the average flux value in dry periods was 5,550 ± 4,420 pg/m(2) day. The obtained deposition values were lower than the reported values given for the urban and industrialized areas, yet close to the ones for the rural sites. The reported deposition values were also influenced by the type of the instruments used. The average dry deposition and total deposition velocity values calculated based on deposition and concentration values were found as 0.23 ± 0.21 and 0.13 ± 0.13 cm/s, respectively.

  15. Average grip strength: a meta-analysis of data obtained with a Jamar dynamometer from individuals 75 years or more of age.

    PubMed

    Bohannon, Richard W; Bear-Lehman, Jane; Desrosiers, Johanne; Massy-Westropp, Nicola; Mathiowetz, Virgil

    2007-01-01

    Although strength diminishes with age, average values for grip strength have not been available heretofore for discrete strata after 75 years. The purpose of this meta-analysis was to provide average values for the left and right hands of men and women 75-79, 80-84, 85-89, and 90-99 years. Contributing to the analysis were 7 studies and 739 subjects with whom the Jamar dynamometer and standard procedures were employed. Based on the analysis, average values for the left and right hands of men and women in each age stratum were derived. The derived values can serve as a standard of comparison for individual patients. An individual whose grip strength is below the lower limit of the confidence intervals of each stratum can be confidently considered to have less than average grip strength.

  16. Aerosol remote sensing in polar regions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tomasi, Claudio; Kokhanovsky, Alexander A.; Lupi, Angelo

    Multi-year sets of ground-based sun-photometer measurements conducted at 12 Arctic sites and 9 Antarctic sites were examined to determine daily mean values of aerosol optical thickness τ(λ) at visible and near-infrared wavelengths, from which best-fit values of Ångström's exponent α were calculated. Analysing these data, the monthly mean values of τ(0.50 μm) and α and the relative frequency histograms of the daily mean values of both parameters were determined for winter–spring and summer–autumn in the Arctic and for austral summer in Antarctica. The Arctic and Antarctic covariance plots of the seasonal median values of α versus τ(0.50 μm) showed: (i)more » a considerable increase in τ(0.50 μm) for the Arctic aerosol from summer to winter–spring, without marked changes in α; and (ii) a marked increase in τ(0.50 μm) passing from the Antarctic Plateau to coastal sites, whereas α decreased considerably due to the larger fraction of sea-salt aerosol. Good agreement was found when comparing ground-based sun-photometer measurements of τ(λ) and α at Arctic and Antarctic coastal sites with Microtops measurements conducted during numerous AERONET/MAN cruises from 2006 to 2013 in three Arctic Ocean sectors and in coastal and off-shore regions of the Southern Atlantic, Pacific, and Indian Oceans, and the Antarctic Peninsula. Lidar measurements were also examined to characterise vertical profiles of the aerosol backscattering coefficient measured throughout the year at Ny-Ålesund. Satellite-based MODIS, MISR, and AATSR retrievals of τ(λ) over large parts of the oceanic polar regions during spring and summer were in close agreement with ship-borne and coastal ground-based sun-photometer measurements. An overview of the chemical composition of mode particles is also presented, based on in-situ measurements at Arctic and Antarctic sites. Fourteen log-normal aerosol number size-distributions were defined to represent the average features of nuclei, accumulation and coarse mode particles for Arctic haze, summer background aerosol, Asian dust and boreal forest fire smoke, and for various background austral summer aerosol types at coastal and high-altitude Antarctic sites. The main columnar aerosol optical characteristics were determined for all 14 particle modes, based on in-situ measurements of the scattering and absorption coefficients. Diurnally averaged direct aerosol-induced radiative forcing and efficiency were calculated for a set of multimodal aerosol extinction models, using various Bidirectional Reflectance Distribution Function models over vegetation-covered, oceanic and snow-covered surfaces. These gave a reliable measure of the pronounced effects of aerosols on the radiation balance of the surface–atmosphere system over polar regions.« less

  17. Aerosol Remote Sensing in Polar Regions

    NASA Technical Reports Server (NTRS)

    Tomasi, Claudio; Kokhanovsky, Alexander A.; Lupi, Angelo; Ritter, Christoph; Smirnov, Alexander; O'Neill, Norman T.; Stone, Robert S.; Holben, Brent N.; Nyeki, Stephan; Wehrli, Christoph

    2014-01-01

    Multi-year sets of ground-based sun-photometer measurements conducted at 12 Arctic sites and 9 Antarctic sites were examined to determine daily mean values of aerosol optical thickness tau(lambda) at visible and near-infrared wavelengths, from which best-fit values of Ångström's exponent alpha were calculated. Analyzing these data, the monthly mean values of tau(0.50 micrometers) and alpha and the relative frequency histograms of the daily mean values of both parameters were determined for winter-spring and summer-autumn in the Arctic and for austral summer in Antarctica. The Arctic and Antarctic covariance plots of the seasonal median values of alpha versus tau(0.50 micrometers) showed: (i) a considerable increase in tau(0.50 micrometers) for the Arctic aerosol from summer to winter-spring, without marked changes in alpha; and (ii) a marked increase in tau(0.50 micrometer) passing from the Antarctic Plateau to coastal sites, whereas alpha decreased considerably due to the larger fraction of sea-salt aerosol. Good agreement was found when comparing ground-based sun-photometer measurements of tau(lambda) and alpha at Arctic and Antarctic coastal sites with Microtops measurements conducted during numerous AERONET/MAN cruises from 2006 to 2013 in three Arctic Ocean sectors and in coastal and off-shore regions of the Southern Atlantic, Pacific, and Indian Oceans, and the Antarctic Peninsula. Lidar measurements were also examined to characterize vertical profiles of the aerosol backscattering coefficient measured throughout the year at Ny-Ålesund. Satellite-based MODIS, MISR, and AATSR retrievals of tau(lambda) over large parts of the oceanic polar regions during spring and summer were in close agreement with ship-borne and coastal ground-based sun-photometer measurements. An overview of the chemical composition of mode particles is also presented, based on in-situ measurements at Arctic and Antarctic sites. Fourteen log-normal aerosol number size-distributions were defined to represent the average features of nuclei, accumulation and coarse mode particles for Arctic haze, summer background aerosol, Asian dust and boreal forest fire smoke, and for various background austral summer aerosol types at coastal and high-altitude Antarctic sites. The main columnar aerosol optical characteristics were determined for all 14 particle modes, based on in-situ measurements of the scattering and absorption coefficients. Diurnally averaged direct aerosol-induced radiative forcing and efficiency were calculated for a set of multimodal aerosol extinction models, using various Bidirectional Reflectance Distribution Function models over vegetation-covered, oceanic and snow-covered surfaces. These gave a reliable measure of the pronounced effects of aerosols on the radiation balance of the surface-atmosphere system over polar regions.

  18. Aerosol remote sensing in polar regions

    DOE PAGES

    Tomasi, Claudio; Kokhanovsky, Alexander A.; Lupi, Angelo; ...

    2015-01-01

    Multi-year sets of ground-based sun-photometer measurements conducted at 12 Arctic sites and 9 Antarctic sites were examined to determine daily mean values of aerosol optical thickness τ(λ) at visible and near-infrared wavelengths, from which best-fit values of Ångström's exponent α were calculated. Analysing these data, the monthly mean values of τ(0.50 μm) and α and the relative frequency histograms of the daily mean values of both parameters were determined for winter–spring and summer–autumn in the Arctic and for austral summer in Antarctica. The Arctic and Antarctic covariance plots of the seasonal median values of α versus τ(0.50 μm) showed: (i)more » a considerable increase in τ(0.50 μm) for the Arctic aerosol from summer to winter–spring, without marked changes in α; and (ii) a marked increase in τ(0.50 μm) passing from the Antarctic Plateau to coastal sites, whereas α decreased considerably due to the larger fraction of sea-salt aerosol. Good agreement was found when comparing ground-based sun-photometer measurements of τ(λ) and α at Arctic and Antarctic coastal sites with Microtops measurements conducted during numerous AERONET/MAN cruises from 2006 to 2013 in three Arctic Ocean sectors and in coastal and off-shore regions of the Southern Atlantic, Pacific, and Indian Oceans, and the Antarctic Peninsula. Lidar measurements were also examined to characterise vertical profiles of the aerosol backscattering coefficient measured throughout the year at Ny-Ålesund. Satellite-based MODIS, MISR, and AATSR retrievals of τ(λ) over large parts of the oceanic polar regions during spring and summer were in close agreement with ship-borne and coastal ground-based sun-photometer measurements. An overview of the chemical composition of mode particles is also presented, based on in-situ measurements at Arctic and Antarctic sites. Fourteen log-normal aerosol number size-distributions were defined to represent the average features of nuclei, accumulation and coarse mode particles for Arctic haze, summer background aerosol, Asian dust and boreal forest fire smoke, and for various background austral summer aerosol types at coastal and high-altitude Antarctic sites. The main columnar aerosol optical characteristics were determined for all 14 particle modes, based on in-situ measurements of the scattering and absorption coefficients. Diurnally averaged direct aerosol-induced radiative forcing and efficiency were calculated for a set of multimodal aerosol extinction models, using various Bidirectional Reflectance Distribution Function models over vegetation-covered, oceanic and snow-covered surfaces. These gave a reliable measure of the pronounced effects of aerosols on the radiation balance of the surface–atmosphere system over polar regions.« less

  19. Observation of Electron Neutrino Appearance in a Muon Neutrino Beam

    NASA Astrophysics Data System (ADS)

    Abe, K.; Adam, J.; Aihara, H.; Akiri, T.; Andreopoulos, C.; Aoki, S.; Ariga, A.; Ariga, T.; Assylbekov, S.; Autiero, D.; Barbi, M.; Barker, G. J.; Barr, G.; Bass, M.; Batkiewicz, M.; Bay, F.; Bentham, S. W.; Berardi, V.; Berger, B. E.; Berkman, S.; Bertram, I.; Bhadra, S.; Blaszczyk, F. d. M.; Blondel, A.; Bojechko, C.; Bordoni, S.; Boyd, S. B.; Brailsford, D.; Bravar, A.; Bronner, C.; Buchanan, N.; Calland, R. G.; Caravaca Rodríguez, J.; Cartwright, S. L.; Castillo, R.; Catanesi, M. G.; Cervera, A.; Cherdack, D.; Christodoulou, G.; Clifton, A.; Coleman, J.; Coleman, S. J.; Collazuol, G.; Connolly, K.; Cremonesi, L.; Dabrowska, A.; Danko, I.; Das, R.; Davis, S.; de Perio, P.; De Rosa, G.; Dealtry, T.; Dennis, S. R.; Densham, C.; Di Lodovico, F.; Di Luise, S.; Drapier, O.; Duboyski, T.; Duffy, K.; Dufour, F.; Dumarchez, J.; Dytman, S.; Dziewiecki, M.; Emery, S.; Ereditato, A.; Escudero, L.; Finch, A. J.; Floetotto, L.; Friend, M.; Fujii, Y.; Fukuda, Y.; Furmanski, A. P.; Galymov, V.; Gaudin, A.; Giffin, S.; Giganti, C.; Gilje, K.; Goeldi, D.; Golan, T.; Gomez-Cadenas, J. J.; Gonin, M.; Grant, N.; Gudin, D.; Hadley, D. R.; Haesler, A.; Haigh, M. D.; Hamilton, P.; Hansen, D.; Hara, T.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayato, Y.; Hearty, C.; Helmer, R. L.; Hierholzer, M.; Hignight, J.; Hillairet, A.; Himmel, A.; Hiraki, T.; Hirota, S.; Holeczek, J.; Horikawa, S.; Huang, K.; Ichikawa, A. K.; Ieki, K.; Ieva, M.; Ikeda, M.; Imber, J.; Insler, J.; Irvine, T. J.; Ishida, T.; Ishii, T.; Ives, S. J.; Iyogi, K.; Izmaylov, A.; Jacob, A.; Jamieson, B.; Johnson, R. A.; Jo, J. H.; Jonsson, P.; Jung, C. K.; Kaboth, A. C.; Kajita, T.; Kakuno, H.; Kameda, J.; Kanazawa, Y.; Karlen, D.; Karpikov, I.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kielczewska, D.; Kikawa, T.; Kilinski, A.; Kim, J.; Kisiel, J.; Kitching, P.; Kobayashi, T.; Koch, L.; Kolaceke, A.; Konaka, A.; Kormos, L. L.; Korzenev, A.; Koseki, K.; Koshio, Y.; Kreslo, I.; Kropp, W.; Kubo, H.; Kudenko, Y.; Kumaratunga, S.; Kurjata, R.; Kutter, T.; Lagoda, J.; Laihem, K.; Lamont, I.; Laveder, M.; Lawe, M.; Lazos, M.; Lee, K. P.; Licciardi, C.; Lindner, T.; Lister, C.; Litchfield, R. P.; Longhin, A.; Ludovici, L.; Macaire, M.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Marino, A. D.; Marteau, J.; Martin, J. F.; Maruyama, T.; Marzec, J.; Mathie, E. L.; Matveev, V.; Mavrokoridis, K.; Mazzucato, E.; McCarthy, M.; McCauley, N.; McFarland, K. S.; McGrew, C.; Metelko, C.; Mezzetto, M.; Mijakowski, P.; Miller, C. A.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Monfregola, L.; Moriyama, S.; Mueller, Th. A.; Murakami, A.; Murdoch, M.; Murphy, S.; Myslik, J.; Nagasaki, T.; Nakadaira, T.; Nakahata, M.; Nakai, T.; Nakamura, K.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Naples, D.; Nielsen, C.; Nirkko, M.; Nishikawa, K.; Nishimura, Y.; O'Keeffe, H. M.; Ohta, R.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Owen, R. A.; Oyama, Y.; Palladino, V.; Paolone, V.; Payne, D.; Pearce, G. F.; Perevozchikov, O.; Perkin, J. D.; Petrov, Y.; Pickard, L. J.; Pinzon Guerra, E. S.; Pistillo, C.; Plonski, P.; Poplawska, E.; Popov, B.; Posiadala, M.; Poutissou, J.-M.; Poutissou, R.; Przewlocki, P.; Quilain, B.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A. M.; Redij, A.; Reeves, M.; Reinherz-Aronis, E.; Retiere, F.; Robert, A.; Rodrigues, P. A.; Rojas, P.; Rondio, E.; Roth, S.; Rubbia, A.; Ruterbories, D.; Sacco, R.; Sakashita, K.; Sánchez, F.; Sato, F.; Scantamburlo, E.; Scholberg, K.; Schwehr, J.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shiozawa, M.; Short, S.; Shustrov, Y.; Sinclair, P.; Smith, B.; Smith, R. J.; Smy, M.; Sobczyk, J. T.; Sobel, H.; Sorel, M.; Southwell, L.; Stamoulis, P.; Steinmann, J.; Still, B.; Suda, Y.; Suzuki, A.; Suzuki, K.; Suzuki, S. Y.; Suzuki, Y.; Szeglowski, T.; Tacik, R.; Tada, M.; Takahashi, S.; Takeda, A.; Takeuchi, Y.; Tanaka, H. K.; Tanaka, H. A.; Tanaka, M. M.; Terhorst, D.; Terri, R.; Thompson, L. F.; Thorley, A.; Tobayama, S.; Toki, W.; Tomura, T.; Totsuka, Y.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Ueno, K.; Vacheret, A.; Vagins, M.; Vasseur, G.; Wachala, T.; Waldron, A. V.; Walter, C. W.; Wark, D.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilkinson, C.; Williamson, Z.; Wilson, J. R.; Wilson, R. J.; Wongjirad, T.; Yamada, Y.; Yamamoto, K.; Yanagisawa, C.; Yen, S.; Yershov, N.; Yokoyama, M.; Yuan, T.; Zalewska, A.; Zalipska, J.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; Żmuda, J.; T2K Collaboration

    2014-02-01

    The T2K experiment has observed electron neutrino appearance in a muon neutrino beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV. A total of 28 electron neutrino events were detected with an energy distribution consistent with an appearance signal, corresponding to a significance of 7.3σ when compared to 4.92±0.55 expected background events. In the Pontecorvo-Maki-Nakagawa-Sakata mixing model, the electron neutrino appearance signal depends on several parameters including three mixing angles θ12, θ23, θ13, a mass difference Δm322 and a CP violating phase δCP. In this neutrino oscillation scenario, assuming |Δm322|=2.4×10-3 eV2, sin2θ23=0.5, and Δm322>0 (Δm322<0), a best-fit value of sin22θ13=0.140-0.032+0.038 (0.170-0.037+0.045) is obtained at δCP=0. When combining the result with the current best knowledge of oscillation parameters including the world average value of θ13 from reactor experiments, some values of δCP are disfavored at the 90% C.L.

  20. Background evaluation for the neutron sources in the Daya Bay experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gu, W. Q.; Cao, G. F.; Chen, X. H.

    2016-07-06

    Here, we present an evaluation of the background induced by 241Am–13C neutron calibration sources in the Daya Bay reactor neutrino experiment. Furthermore, as a significant background for electron-antineutrino detection at 0.26 ± 0.12 detector per day on average, it has been estimated by a Monte Carlo simulation that was benchmarked by a special calibration data set. This dedicated data set also provides the energy spectrum of the background.

  1. Fine particle water and pH in the Eastern Mediterranean: Sources, variability and implications for nutrients availability

    NASA Astrophysics Data System (ADS)

    Bougiatioti, Aikaterini; Nikolaou, Panayiota; Stavroulas, Iasonas; Kouvarakis, Giorgos; Nenes, Athanasios; Weber, Rodney; Kanakidou, Maria; Mihalopoulos, Nikolaos

    2016-04-01

    Atmospheric particles have the ability to absorb significant amounts of water, which greatly impacts on their physical and chemical properties. Direclty linked to aerosol pH and LWC is the bioavailability of nutrients contained within mineral dust, involving pH-dependent catalyzed redox-reaction pathways. Liquid water content (LWC) and pH, even though are important constituents of the aerosol phase, are rarely monitored. Direct measurements of aerosol pH "in situ" are scarce and require considerations owing to the non-conserved nature of the hydronium ion and partial dissociation of inorganic and organic electrolytes in the aerosol. To overcome these challenges, indirect alternatives such as measuring the semi-volatile partitioning of key species sensitive to pH, combined with comprehensive models are used to provide a reasonably accurate estimate of pH that can be carried out with routine measurements. Using concurrent measurements of aerosol chemical composition, tandem light scattering coefficients and the thermodynamic model ISORROPIA-II, LWC mass concentrations associated with the aerosol inorganic and organic components are determined for the remote background site of Finokalia, Crete. The predicted water was subsequently compared to the one measured by the ambient versus dry light scattering coefficients. The sum of Winorg and Worg was highly correlated and in close agreement with the measured LWC (on average within 10%), with slope 0.92 (R2=0.8) for the whole measurement period between August and November 2012 (n=5201 points). As expected, the highest fine aerosol water values are observed during night-time, when RH is at its maximum, resulting in important water uptake. The average concentration of total aerosol water was found to be 2.19±1.75 μg m-3, which according to the dry mass measurements, can contribute on average up to 33% to the total aerosol submicron mass. The average Worg was found to be 0.56±0.37 μg m-3, which constitutes about 28% of the total calculated water. Particle pH is also calculated with the help of ISORROPIA-II, and during the studied period, values varied from 0.5 to 2.8, indicating that the aerosol was highly acidic. pH values were also studied depending on the source/origin of the sampled air masses and biomass burning aerosol was found to exhibit the highest values of PM1 pH and the lowest values in total water mass concentrations. The two natural sources, namely mineral and marine origin, contained the largest amounts of total submicron water and the lowest contribution of organic water, as expected. The low pH values estimated for the studied period in the submicron mode and independently of the air masses' origin could potentially have important implications for nutrient availability, especially for phosphorus solubility, which is the nutrient limiting sea water productivity of the Eastern Mediterranean.

  2. A Stochastic Kinematic Model of Class Averaging in Single-Particle Electron Microscopy

    PubMed Central

    Park, Wooram; Midgett, Charles R.; Madden, Dean R.; Chirikjian, Gregory S.

    2011-01-01

    Single-particle electron microscopy is an experimental technique that is used to determine the 3D structure of biological macromolecules and the complexes that they form. In general, image processing techniques and reconstruction algorithms are applied to micrographs, which are two-dimensional (2D) images taken by electron microscopes. Each of these planar images can be thought of as a projection of the macromolecular structure of interest from an a priori unknown direction. A class is defined as a collection of projection images with a high degree of similarity, presumably resulting from taking projections along similar directions. In practice, micrographs are very noisy and those in each class are aligned and averaged in order to reduce the background noise. Errors in the alignment process are inevitable due to noise in the electron micrographs. This error results in blurry averaged images. In this paper, we investigate how blurring parameters are related to the properties of the background noise in the case when the alignment is achieved by matching the mass centers and the principal axes of the experimental images. We observe that the background noise in micrographs can be treated as Gaussian. Using the mean and variance of the background Gaussian noise, we derive equations for the mean and variance of translational and rotational misalignments in the class averaging process. This defines a Gaussian probability density on the Euclidean motion group of the plane. Our formulation is validated by convolving the derived blurring function representing the stochasticity of the image alignments with the underlying noiseless projection and comparing with the original blurry image. PMID:21660125

  3. Language-Related Values, Reading Amount, and Reading Comprehension in Students with Migration Backgrounds

    ERIC Educational Resources Information Center

    El-Khechen, Wahiba; Ferdinand, Hanna D.; Steinmayr, Ricarda; McElvany, Nele

    2016-01-01

    Background: Although various studies on general language performance have investigated determinants of students' reading comprehension (e.g., reading amount), they have paid insufficient attention to how students perceive parental values influence their language-related values and behaviour--and, as a consequence, their performance. This is…

  4. Mercury speciation in sediments at a municipal sewage sludge marine disposal site.

    PubMed

    Shoham-Frider, E; Shelef, G; Kress, N

    2007-12-01

    Mercury speciation was performed in excess activated sewage sludge (ASS) and in marine sediments collected at the AAS disposal site off the Mediterranean coast of Israel in order to characterize the spatial and vertical distribution of different mercury species and assess their environmental impact. Total Hg (HgT) concentrations ranged between 0.19 and 1003ng/g at the polluted stations and 5.7 and 72.8ng/g at the background station, while the average concentration in ASS was 1181+/-273ng/g. Only at the polluted stations did HgT concentrations decrease exponentially with sediment depth, reaching background values at 16-20cm, the vertical distribution resulting from mixing of natural sediment with ASS solids and bioturbation by large populations of polycheates. Average Methyl Hg (MeHg) concentration in ASS was 39.7+/-7.1ng/g, ca. 3% of the HgT concentration, while the background concentrations ranged between 0.1 and 0.61ng/g. MeHg concentrations in surficial polluted sediments were 0.7-5.9ng/g (ca. 0.5% of the HgT) and decreased vertically, similar to HgT. A positive correlation between MeHg and Hg only at the polluted stations, higher MeHg concentrations at the surface of the sediment and not below the redoxline, and no seasonality in the concentrations suggest that the MeHg originated from the ASS and not from in situ methylation. By doing selective extractions, we found that ca. 80% of the total Hg in ASS and polluted sediments was strongly bound to amorphous organo-sulfur and to inorganic sulfide species that are not bioavailable. The fractions with potential bioaccessible Hg had maximal concentrations in the range in which biotic effects should be expected. Therefore, although no bioaccumulation was found in the biota in the area, the concentration in the polluted sediments are not negligible and should be carefully monitored.

  5. [Heavy metals and hydrocarbons content in soils of settlements of the Yamal-Nenets autonomous region].

    PubMed

    Alekseev, I I; Abakumov, E V; Shamilishvili, G A; Lodygin, E D

    In August 2015 there were executed investigations on the study of the soils diversity of the Yamal-Nenets Autonomous Okrug. One of the directions of this work got be the study of urban soils of settlements of the Yamal-Nenents Autonomous Okrug. The sectors for the observation were settlement of Harsaim, village Aksarka, city of Salekhard, settlement Harp and city of Labytnangi. About 20 soil samples were collected during the field work. Samples were collected from a depth of 0-5 cm and 5-20 cm. Heavy metals (HM) were detected with the use of X-ray fluorescent analyzer “Spectroscan-MAX”. The HM content values were compared with the corresponding Approxible Permissible Concentrations and Maximum Allowable Concentrations (MAC) adopted in Russia. Hydrocarbons content was determined by gravimetric method. Values of the hydrocarbons content in studied soils were compared with the existing regulations of the Russian Federation. The levels of soil contamination by hydrocarbons were determined. The study of soil samples from different settlements allowed to reveal characteristic features of soil contamination of separate settlements by HM and hydrocarbons and to compare them against each other. The vast majority of samples are characterized by arsenic exceedance of MAC, which should indicate to a high regional background of this element. For a more adequate assessment of the Zc meaning as the value of the total pollution index of soils there were used not only arithmetical average values of the coefficients of the chemical composition concentration (Kc), but also their average geometric values. According to levels of total soil contamination most of soil samples are characterized as non-hazardous (Zc<16). Calculation of soil pollution index showed that the most of soil samples have values less than 1. It characterizes soils as unpolluted. Statistical processing of obtained data in the media of the analytical software interface STATISTICA 10 showed a statistically significant difference in the content ofHM and hydrocarbons for the layer of 0-20 cm of the soils for three elements (Cu, Zn, Ni).

  6. Genome-wide characterization of genetic diversity and population structure in Secale

    PubMed Central

    2014-01-01

    Background Numerous rye accessions are stored in ex situ genebanks worldwide. Little is known about the extent of genetic diversity contained in any of them and its relation to contemporary varieties, since to date rye genetic diversity studies had a very limited scope, analyzing few loci and/ or few accessions. Development of high throughput genotyping methods for rye opened the possibility for genome wide characterizations of large accessions sets. In this study we used 1054 Diversity Array Technology (DArT) markers with defined chromosomal location to characterize genetic diversity and population structure in a collection of 379 rye accessions including wild species, landraces, cultivated materials, historical and contemporary rye varieties. Results Average genetic similarity (GS) coefficients and average polymorphic information content (PIC) values varied among chromosomes. Comparison of chromosome specific average GS within and between germplasm sub-groups indicated regions of chromosomes 1R and 4R as being targeted by selection in current breeding programs. Bayesian clustering, principal coordinate analysis and Neighbor Joining clustering demonstrated that source and improvement status contributed significantly to the structure observed in the analyzed set of Secale germplasm. We revealed a relatively limited diversity in improved rye accessions, both historical and contemporary, as well as lack of correlation between clustering of improved accessions and geographic origin, suggesting common genetic background of rye accessions from diverse geographic regions and extensive germplasm exchange. Moreover, contemporary varieties were distinct from the remaining accessions. Conclusions Our results point to an influence of reproduction methods on the observed diversity patterns and indicate potential of ex situ collections for broadening the genetic diversity in rye breeding programs. Obtained data show that DArT markers provide a realistic picture of the genetic diversity and population structure present in the collection of 379 rye accessions and are an effective platform for rye germplasm characterization and association mapping studies. PMID:25085433

  7. Differences in prevalence rates of PTSD in various European countries explained by war exposure, other trauma and cultural value orientation

    PubMed Central

    2014-01-01

    Background Guided by previous explorations of historical and cultural influences on the occurrence of PTSD, the aim of the present study was to investigate the contributions of war victimisation (in particular, World War II) and other civil trauma on the prevalence of PTSD, as mediated by cultural value orientation. Secondary data analysis was performed for 12 European countries using data, including PTSD prevalence and number of war victims, crime victims, and natural disaster victims, from different sources. Ten single value orientations, as well as value aggregates for traditional and modern factors, were investigated. Results Whilst differences in PTSD prevalence were strongly associated with war victim rates, associations, albeit weaker, were also found between crime victims and PTSD. When cultural value orientations, such as stimulation and conformity as representatives of modern and traditional values, were included in the multivariate predictions of PTSD prevalence, an average of approximately 80% of PTSD variance could be explained by the model, independent of the type of trauma exposure. Conclusion The results suggest that the aftermath of war contributes to current PTSD prevalence, which may be explained by the high proportion of the older population who directly or indirectly experienced traumatic war experiences. Additional findings for other types of civil trauma point towards an interaction between value orientation and country-specific trauma rates. Particularly, being personally oriented towards stimulation appears to interact with differences in trauma prevalence. Thus, cultural value orientation might be viewed not only as an individual intrinsic process but also as a compensatory strategy after trauma exposure. PMID:24972489

  8. Urban scale air quality modelling using detailed traffic emissions estimates

    NASA Astrophysics Data System (ADS)

    Borrego, C.; Amorim, J. H.; Tchepel, O.; Dias, D.; Rafael, S.; Sá, E.; Pimentel, C.; Fontes, T.; Fernandes, P.; Pereira, S. R.; Bandeira, J. M.; Coelho, M. C.

    2016-04-01

    The atmospheric dispersion of NOx and PM10 was simulated with a second generation Gaussian model over a medium-size south-European city. Microscopic traffic models calibrated with GPS data were used to derive typical driving cycles for each road link, while instantaneous emissions were estimated applying a combined Vehicle Specific Power/Co-operative Programme for Monitoring and Evaluation of the Long-range Transmission of Air Pollutants in Europe (VSP/EMEP) methodology. Site-specific background concentrations were estimated using time series analysis and a low-pass filter applied to local observations. Air quality modelling results are compared against measurements at two locations for a 1 week period. 78% of the results are within a factor of two of the observations for 1-h average concentrations, increasing to 94% for daily averages. Correlation significantly improves when background is added, with an average of 0.89 for the 24 h record. The results highlight the potential of detailed traffic and instantaneous exhaust emissions estimates, together with filtered urban background, to provide accurate input data to Gaussian models applied at the urban scale.

  9. The genome-wide structure of two economically important indigenous Sicilian cattle breeds.

    PubMed

    Mastrangelo, S; Saura, M; Tolone, M; Salces-Ortiz, J; Di Gerlando, R; Bertolini, F; Fontanesi, L; Sardina, M T; Serrano, M; Portolano, B

    2014-11-01

    Genomic technologies, such as high-throughput genotyping based on SNP arrays, provided background information concerning genome structure in domestic animals. The aim of this work was to investigate the genetic structure, the genome-wide estimates of inbreeding, coancestry, effective population size (Ne), and the patterns of linkage disequilibrium (LD) in 2 economically important Sicilian local cattle breeds, Cinisara (CIN) and Modicana (MOD), using the Illumina Bovine SNP50K v2 BeadChip. To understand the genetic relationship and to place both Sicilian breeds in a global context, genotypes from 134 other domesticated bovid breeds were used. Principal component analysis showed that the Sicilian cattle breeds were closer to individuals of Bos taurus taurus from Eurasia and formed nonoverlapping clusters with other breeds. Between the Sicilian cattle breeds, MOD was the most differentiated, whereas the animals belonging to the CIN breed showed a lower value of assignment, the presence of substructure, and genetic links with the MOD breed. The average molecular inbreeding and coancestry coefficients were moderately high, and the current estimates of Ne were low in both breeds. These values indicated a low genetic variability. Considering levels of LD between adjacent markers, the average r(2) in the MOD breed was comparable to those reported for others cattle breeds, whereas CIN showed a lower value. Therefore, these results support the need of more dense SNP arrays for a high-power association mapping and genomic selection efficiency, particularly for the CIN cattle breed. Controlling molecular inbreeding and coancestry would restrict inbreeding depression, the probability of losing beneficial rare alleles, and therefore the risk of extinction. The results generated from this study have important implications for the development of conservation and/or selection breeding programs in these 2 local cattle breeds.

  10. Soy foods have low glycemic and insulin response indices in normal weight subjects

    PubMed Central

    2006-01-01

    Background Foods with a low glycemic index (GI) may provide a variety of health benefits. The objective of the present study was to measure the GI and insulin index (II) of select soy foods. Methods The study was conducted in two parts with low-carbohydrate products being tested separately. In Experiment 1, subjects averaged 23.2 years of age with BMI = 22.0 kg/m2, while subjects in Experiment 2 averaged 23.9 years of age with BMI = 21.6 kg/m2. The reference (glucose) and test foods were served in portions containing 10 g of carbohydrates in Experiment 1 (two test foods) and 25 g of carbohydrates in Experiment 2 (four test foods). Subjects consumed the reference food twice and each test food once. For each test, subjects were instructed to consume a fixed portion of the reference food or test food together with 250 g of water within 12 min. Blood samples were collected before each test and at 15, 30, 45, 60, 90, and 120 min after consumption of reference or test foods to quantify glucose and insulin. Two-hour blood glucose and plasma insulin curves were constructed and areas under the curves were calculated. GI and II values for each subject and test food were calculated. Results In Experiment 1, both low-carbohydrate soy foods were shown to have significantly (P < 0.05) lower GI and II values than the reference food. In Experiment 2, three of the four test foods had significantly (P < 0.05) lower GI and II values than the reference food. Conclusion All but one of the soy foods tested had a low GI, suggesting that soy foods may be an appropriate part of diets intended to improve control of blood glucose and insulin levels. PMID:17192192

  11. Elemental composition of ambient aerosols measured with high temporal resolution using an online XRF spectrometer

    NASA Astrophysics Data System (ADS)

    Furger, Markus; Cruz Minguillón, María; Yadav, Varun; Slowik, Jay G.; Hüglin, Christoph; Fröhlich, Roman; Petterson, Krag; Baltensperger, Urs; Prévôt, André S. H.

    2017-06-01

    The Xact 625 Ambient Metals Monitor was tested during a 3-week field campaign at the rural, traffic-influenced site Härkingen in Switzerland during the summer of 2015. The field campaign encompassed the Swiss National Day fireworks event, providing increased concentrations and unique chemical signatures compared to non-fireworks (or background) periods. The objective was to evaluate the data quality by intercomparison with other independent measurements and test its applicability for aerosol source quantification. The Xact was configured to measure 24 elements in PM10 with 1 h time resolution. Data quality was evaluated for 10 24 h averages of Xact data by intercomparison with 24 h PM10 filter data analysed with ICP-OES for major elements, ICP-MS for trace elements, and gold amalgamation atomic absorption spectrometry for Hg. Ten elements (S, K, Ca, Ti, Mn, Fe, Cu, Zn, Ba, Pb) showed excellent correlation between the compared methods, with r2 values ≥ 0.95. However, the slopes of the regressions between Xact 625 and ICP data varied from 0.97 to 1.8 (average 1.28) and thus indicated generally higher Xact elemental concentrations than ICP for these elements. Possible reasons for these differences are discussed, but further investigations are needed. For the remaining elements no conclusions could be drawn about their quantification for various reasons, mainly detection limit issues. An indirect intercomparison of hourly values was performed for the fireworks peak, which brought good agreement of total masses when the Xact data were corrected with the regressions from the 24 h value intercomparison. The results demonstrate that multi-metal characterization at high-time-resolution capability of Xact is a valuable and practical tool for ambient monitoring.

  12. Dynamic Modularity of Host Protein Interaction Networks in Salmonella Typhi Infection

    PubMed Central

    Dhal, Paltu Kumar; Barman, Ranjan Kumar; Saha, Sudipto; Das, Santasabuj

    2014-01-01

    Background Salmonella Typhi is a human-restricted pathogen, which causes typhoid fever and remains a global health problem in the developing countries. Although previously reported host expression datasets had identified putative biomarkers and therapeutic targets of typhoid fever, the underlying molecular mechanism of pathogenesis remains incompletely understood. Methods We used five gene expression datasets of human peripheral blood from patients suffering from S. Typhi or other bacteremic infections or non-infectious disease like leukemia. The expression datasets were merged into human protein interaction network (PIN) and the expression correlation between the hubs and their interacting proteins was measured by calculating Pearson Correlation Coefficient (PCC) values. The differences in the average PCC for each hub between the disease states and their respective controls were calculated for studied datasets. The individual hubs and their interactors with expression, PCC and average PCC values were treated as dynamic subnetworks. The hubs that showed unique trends of alterations specific to S. Typhi infection were identified. Results We identified S. Typhi infection-specific dynamic subnetworks of the host, which involve 81 hubs and 1343 interactions. The major enriched GO biological process terms in the identified subnetworks were regulation of apoptosis and biological adhesions, while the enriched pathways include cytokine signalling in the immune system and downstream TCR signalling. The dynamic nature of the hubs CCR1, IRS2 and PRKCA with their interactors was studied in detail. The difference in the dynamics of the subnetworks specific to S. Typhi infection suggests a potential molecular model of typhoid fever. Conclusions Hubs and their interactors of the S. Typhi infection-specific dynamic subnetworks carrying distinct PCC values compared with the non-typhoid and other disease conditions reveal new insight into the pathogenesis of S. Typhi. PMID:25144185

  13. Food Prices and Consumer Demand: Differences across Income Levels and Ethnic Groups

    PubMed Central

    Ni Mhurchu, Cliona; Eyles, Helen; Schilling, Chris; Yang, Qing; Kaye-Blake, William; Genç, Murat; Blakely, Tony

    2013-01-01

    Background Targeted food pricing policies may improve population diets. To assess their effects on inequalities, it is important to determine responsiveness to price changes across income levels and ethnic groups. Objective Our goal was to estimate price elasticity (PE) values for major commonly consumed food groups in New Zealand, by income and ethnicity. PE values represent percentage change in demand associated with 1% change in price of that good (own-PE) or another good (cross-PE). Design We used food expenditure data from national household economic surveys in 2007/08 and 2009/10 and Food Price Index data from 2007 and 2010. Adopting an Almost Ideal Demand System approach, own-PE and cross-PE estimates were derived for 24 food categories, household income quintiles, and two ethnic groups (Māori and non-Māori). Results Own-PE estimates (with two exceptions) ranged from −0.44 to −1.78. Cross-PE estimates were generally small; only 31% of absolute values were greater than 0.10. Excluding the outlier ‘energy drinks’, nine of 23 food groups had significantly stronger own-PEs for the lowest versus highest income quintiles (average regression-based difference across food groups −0.30 (95% CI −0.62 to 0.02)). Six own-PEs were significantly stronger among Māori; the average difference for Māori: non-Māori across food groups was −0.26 (95% CI −0.52 to 0.00). Conclusions Food pricing policies have potential to improve population diets. The greater sensitivity of low-income households and Māori to price changes suggests the beneficial effects of such policies on health would be greatest for these groups. PMID:24098408

  14. Absence of disparities in anthropometric measures among Chilean indigenous and non-indigenous newborns

    PubMed Central

    2010-01-01

    Background Studies throughout North America and Europe have documented adverse perinatal outcomes for racial/ethnic minorities. Nonetheless, the contrast in newborn characteristics between indigenous and non-indigenous populations in Latin America has been poorly characterized. This is due to many challenges, including a lack of vital registration information on ethnicity. The objective of this study was to analyze trends in anthropometric measures at birth in Chilean indigenous (Mapuche) and non-indigenous children over a 5-year period. Methods We examined weight and length at birth using information available through a national data base of all birth records for the years 2000 through 2004 (n = 1,166.513). Newborns were classified ethnically according to the origins of the parents' last names. Result The average birthweight was stable over the 5 year period with variations of less than 20 g in each group, and with mean values trivially higher in indigenous newborns. The proportion weighing less than 2500 g at birth increased modestly from 5.2% to 5.6% in non-indigenous newborns whereas the indigenous births remained constant at 5.2%. In multiple regression analyses, adjusting flexibly for gestational age and maternal characteristics, the occurrence of an indigenous surname added only 14 g to an average infant's birthweight while holding other factors constant. Results for length at birth were similar, and adjusted time trend variation in both outcomes was trivially small after adjustment. Anthropometric indexes at birth in Chile are quite favorable by international standards. Conclusion There is only a trivial degree of ethnic disparity in these values, in contrast to conditions for ethnic minorities in other countries. Moreover, these values remained roughly constant over the 5 years of observation in this study. PMID:20598150

  15. Precision half-life measurement of 17F

    NASA Astrophysics Data System (ADS)

    Brodeur, M.; Nicoloff, C.; Ahn, T.; Allen, J.; Bardayan, D. W.; Becchetti, F. D.; Gupta, Y. K.; Hall, M. R.; Hall, O.; Hu, J.; Kelly, J. M.; Kolata, J. J.; Long, J.; O'Malley, P.; Schultz, B. E.

    2016-02-01

    Background: The precise determination of f t values for superallowed mixed transitions between mirror nuclide are gaining attention as they could provide an avenue to test the theoretical corrections used to extract the Vu d matrix element from superallowed pure Fermi transitions. The 17F decay is particularly interesting as it proceeds completely to the ground state of 17O, removing the need for branching ratio measurements. The dominant uncertainty on the f t value of the 17F mirror transition stems from a number of conflicting half-life measurements. Purpose: A precision half-life measurement of 17F was performed and compared to previous results. Methods: The life-time was determined from the β counting of implanted 17F on a Ta foil that was removed from the beam for counting. The 17F beam was produced by transfers reaction and separated by the TwinSol facility of the Nuclear Science Laboratory of the University of Notre Dame. Results: The measured value of t1/2 new=64.402 (42) s is in agreement with several past measurements and represents one of the most precise measurements to date. In anticipation of future measurements of the correlation parameters for the decay and using the new world average t1/2 world=64.398 (61) s, we present a new estimate of the mixing ratio ρ for the mixed transition as well as the correlation parameters based on assuming Standard Model validity. Conclusions: The relative uncertainty on the new world average for the half-life is dominated by the large χ2=31 of the existing measurements. More precision measurements with different systematics are needed to remedy to the situation.

  16. How many steps/day are enough? For older adults and special populations

    PubMed Central

    2011-01-01

    Older adults and special populations (living with disability and/or chronic illness that may limit mobility and/or physical endurance) can benefit from practicing a more physically active lifestyle, typically by increasing ambulatory activity. Step counting devices (accelerometers and pedometers) offer an opportunity to monitor daily ambulatory activity; however, an appropriate translation of public health guidelines in terms of steps/day is unknown. Therefore this review was conducted to translate public health recommendations in terms of steps/day. Normative data indicates that 1) healthy older adults average 2,000-9,000 steps/day, and 2) special populations average 1,200-8,800 steps/day. Pedometer-based interventions in older adults and special populations elicit a weighted increase of approximately 775 steps/day (or an effect size of 0.26) and 2,215 steps/day (or an effect size of 0.67), respectively. There is no evidence to inform a moderate intensity cadence (i.e., steps/minute) in older adults at this time. However, using the adult cadence of 100 steps/minute to demark the lower end of an absolutely-defined moderate intensity (i.e., 3 METs), and multiplying this by 30 minutes produces a reasonable heuristic (i.e., guiding) value of 3,000 steps. However, this cadence may be unattainable in some frail/diseased populations. Regardless, to truly translate public health guidelines, these steps should be taken over and above activities performed in the course of daily living, be of at least moderate intensity accumulated in minimally 10 minute bouts, and add up to at least 150 minutes over the week. Considering a daily background of 5,000 steps/day (which may actually be too high for some older adults and/or special populations), a computed translation approximates 8,000 steps on days that include a target of achieving 30 minutes of moderate-to-vigorous physical activity (MVPA), and approximately 7,100 steps/day if averaged over a week. Measured directly and including these background activities, the evidence suggests that 30 minutes of daily MVPA accumulated in addition to habitual daily activities in healthy older adults is equivalent to taking approximately 7,000-10,000 steps/day. Those living with disability and/or chronic illness (that limits mobility and or/physical endurance) display lower levels of background daily activity, and this will affect whole-day estimates of recommended physical activity. PMID:21798044

  17. The average direct current offset values for small digital audio recorders in an acoustically consistent environment.

    PubMed

    Koenig, Bruce E; Lacey, Douglas S

    2014-07-01

    In this research project, nine small digital audio recorders were tested using five sets of 30-min recordings at all available recording modes, with consistent audio material, identical source and microphone locations, and identical acoustic environments. The averaged direct current (DC) offset values and standard deviations were measured for 30-sec and 1-, 2-, 3-, 6-, 10-, 15-, and 30-min segments. The research found an inverse association between segment lengths and the standard deviation values and that lengths beyond 30 min may not meaningfully reduce the standard deviation values. This research supports previous studies indicating that measured averaged DC offsets should only be used for exclusionary purposes in authenticity analyses and exhibit consistent values when the general acoustic environment and microphone/recorder configurations were held constant. Measured average DC offset values from exemplar recorders may not be directly comparable to those of submitted digital audio recordings without exactly duplicating the acoustic environment and microphone/recorder configurations. © 2014 American Academy of Forensic Sciences.

  18. Spatial averaging of fields from half-wave dipole antennas and corresponding SAR calculations in the NORMAN human voxel model between 65 MHz and 2 GHz.

    PubMed

    Findlay, R P; Dimbylow, P J

    2009-04-21

    If an antenna is located close to a person, the electric and magnetic fields produced by the antenna will vary in the region occupied by the human body. To obtain a mean value of the field for comparison with reference levels, the Institute of Electrical and Electronic Engineers (IEEE) and International Commission on Non-Ionizing Radiation Protection (ICNIRP) recommend spatially averaging the squares of the field strength over the height the body. This study attempts to assess the validity and accuracy of spatial averaging when used for half-wave dipoles at frequencies between 65 MHz and 2 GHz and distances of lambda/2, lambda/4 and lambda/8 from the body. The differences between mean electric field values calculated using ten field measurements and that of the true averaged value were approximately 15% in the 600 MHz to 2 GHz range. The results presented suggest that the use of modern survey equipment, which takes hundreds rather than tens of measurements, is advisable to arrive at a sufficiently accurate mean field value. Whole-body averaged and peak localized SAR values, normalized to calculated spatially averaged fields, were calculated for the NORMAN voxel phantom. It was found that the reference levels were conservative for all whole-body SAR values, but not for localized SAR, particularly in the 1-2 GHz region when the dipole was positioned very close to the body. However, if the maximum field is used for normalization of calculated SAR as opposed to the lower spatially averaged value, the reference levels provide a conservative estimate of the localized SAR basic restriction for all frequencies studied.

  19. Effect of education and clinical assessment on the accuracy of post partum blood loss estimation

    PubMed Central

    2014-01-01

    Background This research aimed to assess the effect of health care provider education on the accuracy of post partum blood loss estimation. Methods A non-randomized observational study that was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia between January 1, 2011 and June 30, 2011. Hundred and twenty three health care providers who are involved in the estimation of post partum blood loss were eligible to participate. The participants were subjected to three research phases and an educational intervention. They have assessed a total of 30 different simulated blood loss stations, with 10 stations in each of the research phases. These phases took place before and after educational sessions on how to visually estimate blood loss and how to best utilize patient data in clinical scenarios. We have assessed the differences between the estimated blood loss and the actual measure. P-values were calculated to assess the differences between the three research phases estimations. Results The participants significantly under-estimated post partum blood loss. The accuracy was improved after training (p-value < 0.0001) and after analysing each patient’s clinical information (p-value = 0.042). The overall results were not affected by the participants’ clinical backgrounds or their years of experience. Under-estimation was more prominent in cases where more than average-excessive blood losses were simulated while over-estimations or accurate estimations were more prominent in less than average blood loss incidents. Conclusion Simple education programmes can improve traditional findings related to under-estimation of blood loss. More sophisticated clinical education programmes may provide additional improvements. PMID:24646156

  20. Probabilistic models for capturing more physicochemical properties on protein-protein interface.

    PubMed

    Guo, Fei; Li, Shuai Cheng; Du, Pufeng; Wang, Lusheng

    2014-06-23

    Protein-protein interactions play a key role in a multitude of biological processes, such as signal transduction, de novo drug design, immune responses, and enzymatic activities. It is of great interest to understand how proteins interact with each other. The general approach is to explore all possible poses and identify near-native ones with the energy function. The key issue here is to design an effective energy function, based on various physicochemical properties. In this paper, we first identify two new features, the coupled dihedral angles on the interfaces and the geometrical information on π-π interactions. We study these two features through statistical methods: a mixture of bivariate von Mises distributions is used to model the correlation of the coupled dihedral angles, while a mixture of bivariate normal distributions is used to model the orientation of the aromatic rings on π-π interactions. Using 6438 complexes, we parametrize the joint distribution of each new feature. Then, we propose a novel method to construct the energy function for protein-protein interface prediction, which includes the new features as well as the existing energy items such as dDFIRE energy, side-chain energy, atom contact energy, and amino acid energy. Experiments show that our method outperforms the state-of-the-art methods, ZRANK and ClusPro. We use the CAPRI evaluation criteria, Irmsd value, and Fnat value. On Benchmark v4.0, our method has an average Irmsd value of 3.39 Å and Fnat value of 62%, which improves upon the average Irmsd value of 3.89 Å and Fnat value of 49% for ZRANK, and the average Irmsd value of 3.99 Å and Fnat value of 46% for ClusPro. On the CAPRI targets, our method has an average Irmsd value of 3.56 Å and Fnat value of 42%, which improves upon the average Irmsd value of 4.27 Å and Fnat value of 39% for ZRANK, the average Irmsd value of 5.15 Å and Fnat value of 30% for ClusPro.

  1. Source apportionment and pollution evaluation of heavy metals in water and sediments of Buriganga River, Bangladesh, using multivariate analysis and pollution evaluation indices.

    PubMed

    Bhuiyan, Mohammad Amir Hossain; Dampare, Samuel B; Islam, M A; Suzuki, Shigeyuki

    2015-01-01

    Concentrations of heavy metals in water and sediment samples of Buriganga River in the capital city Dhaka, Bangladesh, were studied to understand the level of heavy metals and their source apportionment. The results showed that the mean concentrations of heavy metals both in water and sediment samples were very high and, in most cases, exceeded the permissible limits recommended by the Bangladesh government and other international organizations. Significantly higher concentrations of Pb, Cr, Mn, Co, Ni, Cu, Zn, As, and Cd were found in sediment samples. However, average concentrations of metals both in water and sediment samples were above the effect range median. The heavy metal pollution index (HPI) and degree of contamination (Cd) yielded different results in water samples despite significant correlations between them. The heavy metal evaluation index (HEI) showed strong correlations with HPI and Cd and provided better assessment of pollution levels. The enrichment factor (EF) and geoaccumulation index (Igeo) showed the elevated value of Cr, Pb, and Cd in access of background values. The measured elements were subjected to positive matrix factorization (PMF) and examining correlations in order to explain the content, behavior, and source apportionment of metals. PMF resulted in a successful partitioning of variances into sources related to background geochemistry and contaminant influences. However, the PMF approach successfully demarcated the major sources of metals from tannery, paint, municipal sewage, textiles, and agricultural activities.

  2. Effects of variation in background mixing ratios of N2, O2, and Ar on the measurement of δ18O-H2O and δ2H-H2O values by cavity ring-down spectroscopy

    NASA Astrophysics Data System (ADS)

    Johnson, Jennifer E.; Rella, Chris W.

    2017-08-01

    Cavity ring-down spectrometers have generally been designed to operate under conditions in which the background gas has a constant composition. However, there are a number of observational and experimental situations of interest in which the background gas has a variable composition. In this study, we examine the effect of background gas composition on a cavity ring-down spectrometer that measures δ18O-H2O and δ2H-H2O values based on the amplitude of water isotopologue absorption features around 7184 cm-1 (L2120-i, Picarro, Inc.). For background mixtures balanced with N2, the apparent δ18O values deviate from true values by -0.50 ± 0.001 ‰ O2 %-1 and -0.57 ± 0.001 ‰ Ar %-1, and apparent δ2H values deviate from true values by 0.26 ± 0.004 ‰ O2 %-1 and 0.42 ± 0.004 ‰ Ar %-1. The artifacts are the result of broadening, narrowing, and shifting of both the target absorption lines and strong neighboring lines. While the background-induced isotopic artifacts can largely be corrected with simple empirical or semi-mechanistic models, neither type of model is capable of completely correcting the isotopic artifacts to within the inherent instrument precision. The development of strategies for dynamically detecting and accommodating background variation in N2, O2, and/or Ar would facilitate the application of cavity ring-down spectrometers to a new class of observations and experiments.

  3. 4D seismic monitoring of the miscible CO2 flood of Hall-Gurney Field, Kansas, U.S

    USGS Publications Warehouse

    Raef, A.E.; Miller, R.D.; Byrnes, A.P.; Harrison, W.E.

    2004-01-01

    A cost-effective, highly repeatable, 4D-optimized, single-pattern/patch seismic data-acquisition approach with several 3D data sets was used to evaluate the feasibility of imaging changes associated with the " water alternated with gas" (WAG) stage. By incorporating noninversion-based seismic-attribute analysis, the time and cost of processing and interpreting the data were reduced. A 24-ms-thick EOR-CO 2 injection interval-using an average instantaneous frequency attribute (AIF) was targeted. Changes in amplitude response related to decrease in velocity from pore-fluid replacement within this time interval were found to be lower relative to background values than in AIF analysis. Carefully color-balanced AIF-attribute maps established the overall area affected by the injected EOR-CO2.

  4. Acidic deposition on Taiwan and associated precipitation patterns

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, N.H.; Chen, C.S.; Peng, C.M.

    1996-12-31

    The acidic deposition on Taiwan is assessed based on precipitation chemistry observed through a nationwide monitoring network of acid rain. Ten sites have been operated since 1990. These sites were further categorized into five categories, namely, the northern (A), middle (B), southern (C), and eastern (D) Taiwan, and background (E), according to their geographical consideration. As a result, the averages (1990-1994) of pH values for the northern sites were between 4.46-4.63, whereas, the rest sites, excluding a southern site near the industrial area, had their averages greater than 5.0. The average concentrations of sulfate ions for these sites of meanmore » pH < 5.0, ranged between 103 and 148 {mu}eq {ell}{sup -1}. The mean concentrations of nitrate ions for urban sites were about 30-50% of sulfate concentrations. Using these sulfate and nitrate concentrations and rainfall data, the deposition fluxes for these sites were calculated. The overall averages of annual sulfate deposition for five areas (categories A-E) were 118, 60, 64, 60 and 25 kg ha{sup -1}, respectively, which were generally greater than those of 20-40 kg ha{sup -1} observed in the eastern USA. For the nitrate deposition, these five areas had the averages of 59, 38, 33, 40 and 16 kg ha{sup -1}, respectively. One of the important reasons why Taiwan had received higher sulfate and nitrate deposition was due to a great amount of precipitation over this subtropical island. For the northern Taiwan, more than 70% of precipitation events were stratiform and frontal precipitation associated with the northeastern monsoons, and frontal systems during the winter and spring (especially, the Mei-Yu) seasons, respectively. In addition to local effects, the long-range transport of acid substances are thought to play an important role.« less

  5. Contagion in Mass Killings and School Shootings

    PubMed Central

    Towers, Sherry; Gomez-Lievano, Andres; Khan, Maryam; Mubayi, Anuj; Castillo-Chavez, Carlos

    2015-01-01

    Background Several past studies have found that media reports of suicides and homicides appear to subsequently increase the incidence of similar events in the community, apparently due to the coverage planting the seeds of ideation in at-risk individuals to commit similar acts. Methods Here we explore whether or not contagion is evident in more high-profile incidents, such as school shootings and mass killings (incidents with four or more people killed). We fit a contagion model to recent data sets related to such incidents in the US, with terms that take into account the fact that a school shooting or mass murder may temporarily increase the probability of a similar event in the immediate future, by assuming an exponential decay in contagiousness after an event. Conclusions We find significant evidence that mass killings involving firearms are incented by similar events in the immediate past. On average, this temporary increase in probability lasts 13 days, and each incident incites at least 0.30 new incidents (p = 0.0015). We also find significant evidence of contagion in school shootings, for which an incident is contagious for an average of 13 days, and incites an average of at least 0.22 new incidents (p = 0.0001). All p-values are assessed based on a likelihood ratio test comparing the likelihood of a contagion model to that of a null model with no contagion. On average, mass killings involving firearms occur approximately every two weeks in the US, while school shootings occur on average monthly. We find that state prevalence of firearm ownership is significantly associated with the state incidence of mass killings with firearms, school shootings, and mass shootings. PMID:26135941

  6. High dimensional biological data retrieval optimization with NoSQL technology

    PubMed Central

    2014-01-01

    Background High-throughput transcriptomic data generated by microarray experiments is the most abundant and frequently stored kind of data currently used in translational medicine studies. Although microarray data is supported in data warehouses such as tranSMART, when querying relational databases for hundreds of different patient gene expression records queries are slow due to poor performance. Non-relational data models, such as the key-value model implemented in NoSQL databases, hold promise to be more performant solutions. Our motivation is to improve the performance of the tranSMART data warehouse with a view to supporting Next Generation Sequencing data. Results In this paper we introduce a new data model better suited for high-dimensional data storage and querying, optimized for database scalability and performance. We have designed a key-value pair data model to support faster queries over large-scale microarray data and implemented the model using HBase, an implementation of Google's BigTable storage system. An experimental performance comparison was carried out against the traditional relational data model implemented in both MySQL Cluster and MongoDB, using a large publicly available transcriptomic data set taken from NCBI GEO concerning Multiple Myeloma. Our new key-value data model implemented on HBase exhibits an average 5.24-fold increase in high-dimensional biological data query performance compared to the relational model implemented on MySQL Cluster, and an average 6.47-fold increase on query performance on MongoDB. Conclusions The performance evaluation found that the new key-value data model, in particular its implementation in HBase, outperforms the relational model currently implemented in tranSMART. We propose that NoSQL technology holds great promise for large-scale data management, in particular for high-dimensional biological data such as that demonstrated in the performance evaluation described in this paper. We aim to use this new data model as a basis for migrating tranSMART's implementation to a more scalable solution for Big Data. PMID:25435347

  7. Content of Heavy Metal in the Dust of Leisure Squares and Its Health Risk Assessment-A Case Study of Yanta District in Xi'an.

    PubMed

    Shao, Tianjie; Pan, Lihuan; Chen, Zhiqing; Wang, Ruiyuan; Li, Wenjing; Qin, Qing; He, Yuran

    2018-02-25

    Taking Yanta District in Xi'an as the research object, the present study measures the contents of Cadmium (Cd), Lead (Pb), Copper (Cu), Nickel (Ni), and Chromium (Cr) in dust samples and further assesses the health risk of heavy metals intake through dust based on the assessment method of human exposure risk proposed by U.S. EPA, with an aim to investigate the content of heavy metal in the dust of leisure squares and its exposure risk. As the results indicate, the average contents of five heavy metals are obviously higher than the soil background value in Shaanxi Province. Therefore, Cd, Ni, Cu, Pb, and Cr are obviously enriched in urban surface dust in Shaanxi Province, due to the influence of human activities. In addition, it can also be found that the non-carcinogen exposure risk in children is significantly higher than that in adults with the risk values of these five heavy metals all one order of magnitude higher than those of adults. Irrespective of whether addressing the results for children or adults, the non-carcinogen exposure doses of five heavy metals are sorted as Cr > Pb > Cu > Ni > Cd. According to the present situation, for a child, the total non-carcinogenic risk values of five heavy metals have exceeded the safety limit in 11 of the 20 leisure squares in Yanta District of Xi'an. That means the leisure squares are no longer suitable for physical and recreational activities. For the five heavy metals, the average non-carcinogenic risk value of Cr is largest, and causes the largest threat to health in Yanta District, Xi'an. The carcinogenic exposure doses of the heavy metals Cr, Cd, and Ni are very low in respiratory pathways and there is no carcinogenic health risk. In general, the Cr content in dust in domestic cities is higher than that of foreign cities; however, the Pb content is much lower.

  8. Assessing Attitudes towards Statistics among Medical Students: Psychometric Properties of the Serbian Version of the Survey of Attitudes Towards Statistics (SATS)

    PubMed Central

    Stanisavljevic, Dejana; Trajkovic, Goran; Marinkovic, Jelena; Bukumiric, Zoran; Cirkovic, Andja; Milic, Natasa

    2014-01-01

    Background Medical statistics has become important and relevant for future doctors, enabling them to practice evidence based medicine. Recent studies report that students’ attitudes towards statistics play an important role in their statistics achievements. The aim of the study was to test the psychometric properties of the Serbian version of the Survey of Attitudes Towards Statistics (SATS) in order to acquire a valid instrument to measure attitudes inside the Serbian educational context. Methods The validation study was performed on a cohort of 417 medical students who were enrolled in an obligatory introductory statistics course. The SATS adaptation was based on an internationally accepted methodology for translation and cultural adaptation. Psychometric properties of the Serbian version of the SATS were analyzed through the examination of factorial structure and internal consistency. Results Most medical students held positive attitudes towards statistics. The average total SATS score was above neutral (4.3±0.8), and varied from 1.9 to 6.2. Confirmatory factor analysis validated the six-factor structure of the questionnaire (Affect, Cognitive Competence, Value, Difficulty, Interest and Effort). Values for fit indices TLI (0.940) and CFI (0.961) were above the cut-off of ≥0.90. The RMSEA value of 0.064 (0.051–0.078) was below the suggested value of ≤0.08. Cronbach’s alpha of the entire scale was 0.90, indicating scale reliability. In a multivariate regression model, self-rating of ability in mathematics and current grade point average were significantly associated with the total SATS score after adjusting for age and gender. Conclusion Present study provided the evidence for the appropriate metric properties of the Serbian version of SATS. Confirmatory factor analysis validated the six-factor structure of the scale. The SATS might be reliable and a valid instrument for identifying medical students’ attitudes towards statistics in the Serbian educational context. PMID:25405489

  9. Stability and instability of hydromagnetic Taylor-Couette flows

    NASA Astrophysics Data System (ADS)

    Rüdiger, Günther; Gellert, Marcus; Hollerbach, Rainer; Schultz, Manfred; Stefani, Frank

    2018-04-01

    Decades ago S. Lundquist, S. Chandrasekhar, P. H. Roberts and R. J. Tayler first posed questions about the stability of Taylor-Couette flows of conducting material under the influence of large-scale magnetic fields. These and many new questions can now be answered numerically where the nonlinear simulations even provide the instability-induced values of several transport coefficients. The cylindrical containers are axially unbounded and penetrated by magnetic background fields with axial and/or azimuthal components. The influence of the magnetic Prandtl number Pm on the onset of the instabilities is shown to be substantial. The potential flow subject to axial fields becomes unstable against axisymmetric perturbations for a certain supercritical value of the averaged Reynolds number Rm bar =√{ Re ṡ Rm } (with Re the Reynolds number of rotation, Rm its magnetic Reynolds number). Rotation profiles as flat as the quasi-Keplerian rotation law scale similarly but only for Pm ≫ 1 while for Pm ≪ 1 the instability instead sets in for supercritical Rm at an optimal value of the magnetic field. Among the considered instabilities of azimuthal fields, those of the Chandrasekhar-type, where the background field and the background flow have identical radial profiles, are particularly interesting. They are unstable against nonaxisymmetric perturbations if at least one of the diffusivities is non-zero. For Pm ≪ 1 the onset of the instability scales with Re while it scales with Rm bar for Pm ≫ 1. Even superrotation can be destabilized by azimuthal and current-free magnetic fields; this recently discovered nonaxisymmetric instability is of a double-diffusive character, thus excluding Pm = 1. It scales with Re for Pm → 0 and with Rm for Pm → ∞. The presented results allow the construction of several new experiments with liquid metals as the conducting fluid. Some of them are described here and their results will be discussed together with relevant diversifications of the magnetic instability theory including nonlinear numerical studies of the kinetic and magnetic energies, the azimuthal spectra and the influence of the Hall effect.

  10. Methods to estimate effective population size using pedigree data: Examples in dog, sheep, cattle and horse

    PubMed Central

    2013-01-01

    Background Effective population sizes of 140 populations (including 60 dog breeds, 40 sheep breeds, 20 cattle breeds and 20 horse breeds) were computed using pedigree information and six different computation methods. Simple demographical information (number of breeding males and females), variance of progeny size, or evolution of identity by descent probabilities based on coancestry or inbreeding were used as well as identity by descent rate between two successive generations or individual identity by descent rate. Results Depending on breed and method, effective population sizes ranged from 15 to 133 056, computation method and interaction between computation method and species showing a significant effect on effective population size (P < 0.0001). On average, methods based on number of breeding males and females and variance of progeny size produced larger values (4425 and 356, respectively), than those based on identity by descent probabilities (average values between 93 and 203). Since breeding practices and genetic substructure within dog breeds increased inbreeding, methods taking into account the evolution of inbreeding produced lower effective population sizes than those taking into account evolution of coancestry. The correlation level between the simplest method (number of breeding males and females, requiring no genealogical information) and the most sophisticated one ranged from 0.44 to 0.60 according to species. Conclusions When choosing a method to compute effective population size, particular attention should be paid to the species and the specific genetic structure of the population studied. PMID:23281913

  11. Artificial Intelligence in Mitral Valve Analysis

    PubMed Central

    Jeganathan, Jelliffe; Knio, Ziyad; Amador, Yannis; Hai, Ting; Khamooshian, Arash; Matyal, Robina; Khabbaz, Kamal R; Mahmood, Feroze

    2017-01-01

    Background: Echocardiographic analysis of mitral valve (MV) has become essential for diagnosis and management of patients with MV disease. Currently, the various software used for MV analysis require manual input and are prone to interobserver variability in the measurements. Aim: The aim of this study is to determine the interobserver variability in an automated software that uses artificial intelligence for MV analysis. Settings and Design: Retrospective analysis of intraoperative three-dimensional transesophageal echocardiography data acquired from four patients with normal MV undergoing coronary artery bypass graft surgery in a tertiary hospital. Materials and Methods: Echocardiographic data were analyzed using the eSie Valve Software (Siemens Healthcare, Mountain View, CA, USA). Three examiners analyzed three end-systolic (ES) frames from each of the four patients. A total of 36 ES frames were analyzed and included in the study. Statistical Analysis: A multiple mixed-effects ANOVA model was constructed to determine if the examiner, the patient, and the loop had a significant effect on the average value of each parameter. A Bonferroni correction was used to correct for multiple comparisons, and P = 0.0083 was considered to be significant. Results: Examiners did not have an effect on any of the six parameters tested. Patient and loop had an effect on the average parameter value for each of the six parameters as expected (P < 0.0083 for both). Conclusion: We were able to conclude that using automated analysis, it is possible to obtain results with good reproducibility, which only requires minimal user intervention. PMID:28393769

  12. Two Types of Long-duration Quasi-static Evolution of Solar Filaments

    NASA Astrophysics Data System (ADS)

    Xing, C.; Li, H. C.; Jiang, B.; Cheng, X.; Ding, M. D.

    2018-04-01

    In this Letter, we investigate the long-duration quasi-static evolution of 12 pre-eruptive filaments (four active region (AR) and eight quiescent filaments), mainly focusing on the evolution of the filament height in 3D and the decay index of the background magnetic field. The filament height in 3D is derived through two-perspective observations of Solar Dynamics Observatory (SDO) and Solar TErrestrial RElations Observatory (STEREO). The coronal magnetic field is reconstructed using the potential field source surface model. A new finding is that the filaments we studied show two types of long-duration evolution: one type comprises a long-duration static phase and a short, slow rise phase with a duration of less than 12 hr and a speed of 0.1–0.7 km s‑1, while the other one only presents a slow rise phase but with an extremely long duration of more than 60 hr and a smaller speed of 0.01–0.2 km s‑1. At the moment approaching the eruption, the decay index of the background magnetic field at the filament height is similar for both AR and quiescent filaments. The average value and upper limit are ∼0.9 and ∼1.4, close to the critical index of torus instability. Moreover, the filament height and background magnetic field strength are also found to be linearly and exponentially related with the filament length, respectively.

  13. Genome wide linkage disequilibrium and genetic structure in Sicilian dairy sheep breeds.

    PubMed

    Mastrangelo, Salvatore; Di Gerlando, Rosalia; Tolone, Marco; Tortorici, Lina; Sardina, Maria Teresa; Portolano, Baldassare

    2014-10-10

    The recent availability of sheep genome-wide SNP panels allows providing background information concerning genome structure in domestic animals. The aim of this work was to investigate the patterns of linkage disequilibrium (LD), the genetic diversity and population structure in Valle del Belice, Comisana, and Pinzirita dairy sheep breeds using the Illumina Ovine SNP50K Genotyping array. Average r (2) between adjacent SNPs across all chromosomes was 0.155 ± 0.204 for Valle del Belice, 0.156 ± 0.208 for Comisana, and 0.128 ± 0.188 for Pinzirita breeds, and some variations in LD value across chromosomes were observed, in particular for Valle del Belice and Comisana breeds. Average values of r (2) estimated for all pairwise combinations of SNPs pooled over all autosomes were 0.058 ± 0.023 for Valle del Belice, 0.056 ± 0.021 for Comisana, and 0.037 ± 0.017 for Pinzirita breeds. The LD declined as a function of distance and average r (2) was lower than the values observed in other sheep breeds. Consistency of results among the several used approaches (Principal component analysis, Bayesian clustering, F ST, Neighbor networks) showed that while Valle del Belice and Pinzirita breeds formed a unique cluster, Comisana breed showed the presence of substructure. In Valle del Belice breed, the high level of genetic differentiation within breed, the heterogeneous cluster in Admixture analysis, but at the same time the highest inbreeding coefficient, suggested that the breed had a wide genetic base with inbred individuals belonging to the same flock. The Sicilian breeds were characterized by low genetic differentiation and high level of admixture. Pinzirita breed displayed the highest genetic diversity (He, Ne) whereas the lowest value was found in Valle del Belice breed. This study has reported for the first time estimates of LD and genetic diversity from a genome-wide perspective in Sicilian dairy sheep breeds. Our results indicate that breeds formed non-overlapping clusters and are clearly separated populations and that Comisana sheep breed does not constitute a homogenous population. The information generated from this study has important implications for the design and applications of association studies as well as for development of conservation and/or selection breeding programs.

  14. Comparison of spectral estimators for characterizing fractionated atrial electrograms

    PubMed Central

    2013-01-01

    Background Complex fractionated atrial electrograms (CFAE) acquired during atrial fibrillation (AF) are commonly assessed using the discrete Fourier transform (DFT), but this can lead to inaccuracy. In this study, spectral estimators derived by averaging the autocorrelation function at lags were compared to the DFT. Method Bipolar CFAE of at least 16 s duration were obtained from pulmonary vein ostia and left atrial free wall sites (9 paroxysmal and 10 persistent AF patients). Power spectra were computed using the DFT and three other methods: 1. a novel spectral estimator based on signal averaging (NSE), 2. the NSE with harmonic removal (NSH), and 3. the autocorrelation function average at lags (AFA). Three spectral parameters were calculated: 1. the largest fundamental spectral peak, known as the dominant frequency (DF), 2. the DF amplitude (DA), and 3. the mean spectral profile (MP), which quantifies noise floor level. For each spectral estimator and parameter, the significance of the difference between paroxysmal and persistent AF was determined. Results For all estimators, mean DA and mean DF values were higher in persistent AF, while the mean MP value was higher in paroxysmal AF. The differences in means between paroxysmals and persistents were highly significant for 3/3 NSE and NSH measurements and for 2/3 DFT and AFA measurements (p<0.001). For all estimators, the standard deviation in DA and MP values were higher in persistent AF, while the standard deviation in DF value was higher in paroxysmal AF. Differences in standard deviations between paroxysmals and persistents were highly significant in 2/3 NSE and NSH measurements, in 1/3 AFA measurements, and in 0/3 DFT measurements. Conclusions Measurements made from all four spectral estimators were in agreement as to whether the means and standard deviations in three spectral parameters were greater in CFAEs acquired from paroxysmal or in persistent AF patients. Since the measurements were consistent, use of two or more of these estimators for power spectral analysis can be assistive to evaluate CFAE more objectively and accurately, which may lead to improved clinical outcome. Since the most significant differences overall were achieved using the NSE and NSH estimators, parameters measured from their spectra will likely be the most useful for detecting and discerning electrophysiologic differences in the AF substrate based upon frequency analysis of CFAE. PMID:23855345

  15. 40 CFR 133.101 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... arithmetic mean of pollutant parameter values for samples collected in a period of 7 consecutive days. (b) 30-day average. The arithmetic mean of pollutant parameter values of samples collected in a period of 30... percentile value for the 30-day average effluent quality achieved by a treatment works in a period of at...

  16. Effect of coping thickness and background type on the masking ability of a zirconia ceramic.

    PubMed

    Tabatabaian, Farhad; Taghizade, Fateme; Namdari, Mahshid

    2018-01-01

    The masking ability of zirconia ceramics as copings is unclear. The purpose of this in vitro study was to evaluate the effect of coping thickness and background type on the masking ability of a zirconia ceramic and to determine zirconia coping thickness cut offs for masking the backgrounds investigated. Thirty zirconia disks in 3 thickness groups of 0.4, 0.6, and 0.8 mm were placed on 9 backgrounds to measure CIELab color attributes using a spectrophotometer. The backgrounds included A1, A2, and A3.5 shade composite resin, A3 shade zirconia, nickel-chromium alloy, nonprecious gold-colored alloy, amalgam, black, and white. ΔE values were measured to determine color differences between the specimens on the A2 shade composite resin background and the same specimens on the other backgrounds. The color change (ΔE) values were compared with threshold values for acceptability (ΔE=5.5) and perceptibility (ΔE=2.6). Repeated measures ANOVA, the Bonferroni test, and 1-sample t tests were used to analyze data (α=.05). Mean ΔE values ranged between 1.44 and 7.88. The zirconia coping thickness, the background type, and their interaction affected the CIELab and ΔE values (P<.001). To achieve ideal masking, the minimum thickness of a zirconia coping should be 0.4 mm for A1 and A3.5 shade composite resin, A3 shade zirconia, and nonprecious gold-colored alloy, 0.6 mm for amalgam, and 0.8 mm for nickel-chromium alloy. Copyright © 2017 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  17. Investigation of Acoustic Structure Quantification in the Diagnosis of Thyroiditis.

    PubMed

    Park, Jisang; Hong, Hyun Sook; Kim, Chul-Hee; Lee, Eun Hye; Jeong, Sun Hye; Lee, A Leum; Lee, Heon

    2016-03-01

    The objective of this study was to evaluate the ability of acoustic structure quantification (ASQ) to diagnose thyroiditis. The echogenicity of 439 thyroid lobes, as determined using ASQ, was quantified and analyzed retrospectively. Thyroiditis was categorized into five subgroups. The results were presented in a modified chi-square histogram as the mode, average, ratio, blue mode, and blue average. We determined the cutoff values of ASQ from ROC analysis to detect and differentiate thyroiditis from a normal thyroid gland. We obtained data on the sensitivity and specificity of the cutoff values to distinguish between euthyroid patients with thyroiditis and patients with a normal thyroid gland. The mean ASQ values for patients with thyroiditis were statistically significantly greater than those for patients with a normal thyroid gland (p < 0.001). The AUCs were as follows: 0.93 for the ratio, 0.91 for the average, 0.90 for the blue average, 0.87 for the mode, and 0.87 for the blue mode. For the diagnosis of thyroiditis, the cutoff values were greater than 0.27 for the ratio, greater than 116.7 for the mean, and greater than 130.7 for the blue average. The sensitivities and specificities were as follows: 84.0% and 96.6% for the ratio, 85.3% and 83.0%, for the average, and 79.1% and 93.2% for the blue average, respectively. The ASQ parameters were successful in distinguishing patients with thyroiditis from patients with a normal thyroid gland, with likelihood ratios of 24.7 for the ratio, 5.0 for the average, and 11.6 for the blue average. With the use of the aforementioned cutoff values, the sensitivities and specificities for distinguishing between patients with thyroiditis and euthyroid patients without thyroiditis were 77.05% and 94.92% for the ratio, 85.25% and 82.20% for the average, and 77.05% and 92.37% for the blue average, respectively. ASQ can provide objective and quantitative analysis of thyroid echogenicity. ASQ parameters were successful in distinguishing between patients with thyroiditis and individuals without thyroiditis, with likelihood ratios of 24.7 for the ratio, 5.0 for the average, and 11.6 for the blue average.

  18. [Spectrum simulation based on data derived from red tide].

    PubMed

    Liu, Zhen-Yu; Cui, Ting-Wei; Yue, Jie; Jiang, Tao; Cao, Wen-Xi; Ma, Yi

    2011-11-01

    The present paper utilizes the absorption data of red tide water measured during the growing and dying course to retrieve imaginary part of the index of refraction based on Mie theory, carries out the simulation and analysis of average absorption efficiency factors, average backscattering efficiency factors and scattering phase function. The analysis of the simulation shows that Mie theory can be used to reproduce the absorption property of Chaetoceros socialis with an average error of 11%; the average backscattering efficiency factors depend on the value of absorption whose maximum value corresponds to the wavelength range from 400 to 700 nanometer; the average backscattering efficiency factors showed a maximum value on 17th with a low value during the outbreak of red tide and the minimum on 21th; the total scattering, weakly depending on the absorption, is proportional to the size parameters which represent the relative size of cell diameter with respect to the wavelength, while the angle scattering intensity is inversely proportional to wavelength.

  19. Altered Osteocyte-Specific Protein Expression in Bone after Childhood Solid Organ Transplantation

    PubMed Central

    Pereira, Renata C.; Valta, Helena; Tumber, Navdeep; Salusky, Isidro B.; Jalanko, Hannu

    2015-01-01

    Background Bone fragility is common post solid organ transplantation but little is known about bone pathology on a tissue level. Abnormal osteocytic protein expression has been linked to compromised bone health in chronic kidney disease (CKD) and immunosuppressant medications may impact osteocyte function. Methods Transiliac bone biopsies were obtained from 22 pediatric solid organ allograft recipients (average age 15.6 years) an average of 6.3 ± 1.2 years after transplantation and from 12 pediatric pre-dialysis CKD patients (average age 13.2 years). Histomorphometry and immunohistochemistry for FGF23, DMP1, sclerostin, and osteopontin were performed on all biopsies. Results FGF23 and sclerostin were increased in transplant recipients relative to non-transplant CKD, regardless of the type of allograft received and despite, in the case of liver and heart recipients, a higher GFR. Bone DMP1 expression was higher in liver or heart than in kidney recipients, concomitant with higher serum phosphate values. Osteopontin expression was higher in CKD than in transplant recipients (p<0.01). Bone FGF23 and sclerostin correlated directly (r = 0.38, p<0.05); bone FGF23 expression and osteoid thickness correlated inversely (r = - 0.46, p<0.01). Conclusions Solid-organ transplantation is associated with increased FGF23 and sclerostin expression. The contribution of these findings to compromised bone health post transplantation warrants further evaluation. PMID:26390291

  20. Rare earth elements in street dust and associated health risk in a municipal industrial base of central China.

    PubMed

    Sun, Guangyi; Li, Zhonggen; Liu, Ting; Chen, Ji; Wu, Tingting; Feng, Xinbin

    2017-12-01

    The content levels, distribution characteristics, and health risks associated with 15 rare earth elements (REEs) in urban street dust from an industrial city, Zhuzhou, in central China were investigated. The total REE content (∑REE) ranged from 66.1 to 237.4 mg kg -1 , with an average of 115.9 mg kg -1 , which is lower than that of Chinese background soil and Yangtze river sediment. Average content of the individual REE in street dust decreased in the order Ce > La > Nd > Y > Pr > Sm > Gd > Dy > Er > Yb > Eu > Ho > Tb > Tm > Lu. The chondrite-normalized REE pattern indicated light REE (LREE) enrichment, a relatively steep LREE trend, heavy REE (HREE) depletion, a flat HREE trend, a Eu-negative anomaly and a Ce-positive anomaly. Foremost heavy local soil and to less degree anthropogenic pollution are the main sources of REE present in street dust. Health risk associated with the exposure of REE in street dust was assessed based on the carcinogenic and non-carcinogenic effect and lifetime average daily dose. The obtained cancer and non-cancer risk values prompt for no augmented health hazard. However, children had greater health risks than that of adults.

  1. Iodine-129 measurements in soil samples from Dolon village near the Semipalatinsk nuclear test site.

    PubMed

    Endo, Satoru; Tomita, Junpei; Tanaka, Kenichi; Yamamoto, Masayoshi; Fukutani, Satoshi; Imanaka, Tetsuji; Sakaguchi, Aya; Amano, Hikaru; Kawamura, Hidehisa; Kawamura, Hisao; Apsalikov, Kazbek N; Gusev, Boris I; Whitehead, Neil E; Shinkarev, Sergey; Hoshi, Masaharu

    2008-07-01

    Dolon village, located about 60 km from the border of the Semipalatinsk nuclear test site, is known to be heavily contaminated by the first USSR atomic bomb test in August 1949. Soil samples around Dolon were taken in October 2005 in an attempt to evaluate internal thyroid dose arising from incorporation of radioiodine isotopes (mainly (131)I). Iodine-129 in soil was measured by using the technique of accelerator mass spectrometry. The (129)I/(127)I atom ratios measured were in the range from 3.3 x 10(-9) to 3.3 x 10(-7). These values were within the range of the current background level ( approximately 10(-9) to 10(-7)) in the environment, including contributions from the global fallout of atmospheric nuclear tests and local fallout of nuclear facilities. The (129)I atom accumulated level in soil ranged from 1.28 x 10(13) to 1.59 x 10(14) atoms m(-2), the average (8.0 x 10(13)) of which was higher than the background level of (2-5) x 10(13). From the relationship between (129)I and( 137)Cs (corrected for background and decay from 1949 to 2005) accumulated levels, the background level of (129)I and the (129)I/(137)Cs ratio around Dolon were estimated to be (6.4 +/- 0.4) x 10(13) atoms m(-2) and 0.25 +/- 0.16, respectively. This (129)I/(137)Cs ratio is almost similar to the fission yield ratio for (239)Pu fast fission (0.24).

  2. Origins and trends in ethane and propane in the United Kingdom from 1993 to 2012

    NASA Astrophysics Data System (ADS)

    Derwent, R. G.; Field, R. A.; Dumitrean, P.; Murrells, T. P.; Telling, S. P.

    2017-05-01

    Continuous, high frequency in situ observations of ethane and propane began in the United Kingdom in 1993 and have continued through to the present day at a range of kerbside, urban background and rural locations. Whilst other monitored C2 - C8 hydrocarbons have shown dramatic declines in concentrations by close to or over an order of magnitude, ethane and propane levels have remained at or close to their 1993 values. Urban ethane sources appear to be dominated by natural gas leakage. Background levels of ethane associated with long range transport are rising. However, natural gas leakage is not the sole source of urban propane. Oil and gas operations lead to elevated propane levels in urban centres when important refinery operations are located nearby. Weekend versus weekday average diurnal curves for ethane and propane at an urban background site in London show the importance of natural gas leakage for both ethane and propane, and road traffic sources for propane. The road traffic source of propane was tentatively identified as arising from petrol-engined motor vehicle refuelling and showed a strong downwards trend at the long-running urban background and rural sites. The natural gas leakage source of ethane and propane in the observations exhibits an upwards trend whereas that in the UK emission inventory trends downwards. Also, inventory emissions for natural gas leakage appeared to be significantly underestimated compared with the observations. In addition, the observed ethane to propane ratio found here for natural gas leakage strongly disagreed with the inventory ratio.

  3. The Role of Instructional Quality within School Sectors: A Multi-Level Analysis

    ERIC Educational Resources Information Center

    Miller, Saralyn J.

    2013-01-01

    On average, private school students outperform public school students on standardized tests. Research confirms these differences in student scores, but also shows that when student background characteristics are controlled, on average, public school students outperform private school students. Explaining achievement differences between sectors…

  4. Updated folate data in the Dutch Food Composition Database and implications for intake estimates

    PubMed Central

    Westenbrink, Susanne; Jansen-van der Vliet, Martine; van Rossum, Caroline

    2012-01-01

    Background and objective Nutrient values are influenced by the analytical method used. Food folate measured by high performance liquid chromatography (HPLC) or by microbiological assay (MA) yield different results, with in general higher results from MA than from HPLC. This leads to the question of how to deal with different analytical methods in compiling standardised and internationally comparable food composition databases? A recent inventory on folate in European food composition databases indicated that currently MA is more widely used than HPCL. Since older Dutch values are produced by HPLC and newer values by MA, analytical methods and procedures for compiling folate data in the Dutch Food Composition Database (NEVO) were reconsidered and folate values were updated. This article describes the impact of this revision of folate values in the NEVO database as well as the expected impact on the folate intake assessment in the Dutch National Food Consumption Survey (DNFCS). Design The folate values were revised by replacing HPLC with MA values from recent Dutch analyses. Previously MA folate values taken from foreign food composition tables had been recalculated to the HPLC level, assuming a 27% lower value from HPLC analyses. These recalculated values were replaced by the original MA values. Dutch HPLC and MA values were compared to each other. Folate intake was assessed for a subgroup within the DNFCS to estimate the impact of the update. Results In the updated NEVO database nearly all folate values were produced by MA or derived from MA values which resulted in an average increase of 24%. The median habitual folate intake in young children was increased by 11–15% using the updated folate values. Conclusion The current approach for folate in NEVO resulted in more transparency in data production and documentation and higher comparability among European databases. Results of food consumption surveys are expected to show higher folate intakes when using the updated values. PMID:22481900

  5. 40 CFR Table 2 to Subpart Mmmmm of... - Operating Limits for New or Reconstructed Flame Lamination Affected Sources

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... scrubber, maintain the daily average pressure drop across the venturi within the operating range value... . . . You must . . . 1. Scrubber a. Maintain the daily average scrubber inlet liquid flow rate above the minimum value established during the performance test. b. Maintain the daily average scrubber effluent pH...

  6. 40 CFR Table 2 to Subpart Mmmmm of... - Operating Limits for New or Reconstructed Flame Lamination Affected Sources

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... . . . You must . . . 1. Scrubber a. Maintain the daily average scrubber inlet liquid flow rate above the minimum value established during the performance test. b. Maintain the daily average scrubber effluent pH... scrubber, maintain the daily average pressure drop across the venturi within the operating range value...

  7. Tritium concentrations in bees and honey at Los Alamos National Laboratory: 1979-1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fresquez, P.R.; Armstrong, D.R.; Pratt, L.H.

    Honeybees are effective monitors of environmental pollution. The objective of this study was to summarize tritium ({sup 3}H) concentrations in bees and honey collected from within and around Los Alamos National Laboratory (LANL) over an 18-year period. Based on the long-term average, bees from nine out of eleven hives and honey from six out of eleven hives on LANL lands contained {sup 3}H that was significantly higher (p <0.05) than background. The highest average concentration of {sup 3}H in bees (435 pCi mL{sup -1}) collected over the years was from LANL`s Technical Area (TA) 54-a low-level radioactive waste disposal sitemore » (Area G). Similarly, the highest average concentration of {sup 3}H in honey (709 pCi mL{sup - 1}) was collected from a hive located near three {sup 3}H storage ponds at LANL TA-53. The average concentrations of {sup 3}H in bees and honey from background hives was 1.0 pCi mL{sup -1} and 1.5 pCi ML{sup -1}, respectively. Although the concentrations of 3H in bees and honey from most LANL and perimeter (White Rock/Pajarito Acres) areas were significantly higher than background, most areas, with the exception of TA-53 and TA-54, generally exhibited decreasing 3H concentrations over time.« less

  8. Cosmological backreaction within the Szekeres model and emergence of spatial curvature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bolejko, Krzysztof, E-mail: krzysztof.bolejko@sydney.edu.au

    This paper discusses the phenomenon of backreaction within the Szekeres model. Cosmological backreaction describes how the mean global evolution of the Universe deviates from the Friedmannian evolution. The analysis is based on models of a single cosmological environment and the global ensemble of the Szekeres models (of the Swiss-Cheese-type and Styrofoam-type). The obtained results show that non-linear growth of cosmic structures is associated with the growth of the spatial curvature Ω{sub R} (in the FLRW limit Ω{sub R} → Ω {sub k} ). If averaged over global scales the result depends on the assumed global model of the Universe. Withinmore » the Swiss-Cheese model, which does have a fixed background, the volume average follows the evolution of the background, and the global spatial curvature averages out to zero (the background model is the ΛCDM model, which is spatially flat). In the Styrofoam-type model, which does not have a fixed background, the mean evolution deviates from the spatially flat ΛCDM model, and the mean spatial curvature evolves from Ω{sub R} =0 at the CMB to Ω{sub R} ∼ 0.1 at 0 z =. If the Styrofoam-type model correctly captures evolutionary features of the real Universe then one should expect that in our Universe, the spatial curvature should build up (local growth of cosmic structures) and its mean global average should deviate from zero (backreaction). As a result, this paper predicts that the low-redshift Universe should not be spatially flat (i.e. Ω {sub k} ≠ 0, even if in the early Universe Ω {sub k} = 0) and therefore when analysing low- z cosmological data one should keep Ω {sub k} as a free parameter and independent from the CMB constraints.« less

  9. Cosmological backreaction within the Szekeres model and emergence of spatial curvature

    NASA Astrophysics Data System (ADS)

    Bolejko, Krzysztof

    2017-06-01

    This paper discusses the phenomenon of backreaction within the Szekeres model. Cosmological backreaction describes how the mean global evolution of the Universe deviates from the Friedmannian evolution. The analysis is based on models of a single cosmological environment and the global ensemble of the Szekeres models (of the Swiss-Cheese-type and Styrofoam-type). The obtained results show that non-linear growth of cosmic structures is associated with the growth of the spatial curvature ΩScript R (in the FLRW limit ΩScript R → Ωk). If averaged over global scales the result depends on the assumed global model of the Universe. Within the Swiss-Cheese model, which does have a fixed background, the volume average follows the evolution of the background, and the global spatial curvature averages out to zero (the background model is the ΛCDM model, which is spatially flat). In the Styrofoam-type model, which does not have a fixed background, the mean evolution deviates from the spatially flat ΛCDM model, and the mean spatial curvature evolves from ΩScript R =0 at the CMB to ΩScript R ~ 0.1 at 0z =. If the Styrofoam-type model correctly captures evolutionary features of the real Universe then one should expect that in our Universe, the spatial curvature should build up (local growth of cosmic structures) and its mean global average should deviate from zero (backreaction). As a result, this paper predicts that the low-redshift Universe should not be spatially flat (i.e. Ωk ≠ 0, even if in the early Universe Ωk = 0) and therefore when analysing low-z cosmological data one should keep Ωk as a free parameter and independent from the CMB constraints.

  10. Clustering techniques: measuring the performance of contract service providers.

    PubMed

    Cruz, Antonio Miguel; Perilla, Sandra Patricia Usaquén; Pabón, Nidia Nelly Vanegas

    2010-01-01

    This paper investigates the use of clustering technique to characterize the providers of maintenance services in a health-care institution according to their performance. A characterization of the inventory of equipment from seven pilot areas was carried out first (including 264 medical devices). The characterization study concluded that the inventory on a whole is old [exploitation time (ET)/useful life (UL) average is 0.78] and has high maintenance service costs relative to the original cost of acquisition (service cost /acquisition cost average 8.61%). A monitoring of the performance of maintenance service providers was then conducted. The variables monitored were response time (RT), service time (ST), availability, and turnaround time (TAT). Finally, the study grouped maintenance service providers into clusters according to performance. The study grouped maintenance service providers into the following clusters. Cluster 0: Identified with the best performance, the lowest values of TAT, RT, and ST, with an average TAT value of 1.46 days; Clusters 1 and 2: Identified with the poorest performance, highest values of TAT, RT, and ST, and an average TAT value of 9.79 days; and Cluster 3: Identified by medium-quality performance, intermediate values of TAT, RT, and ST, and an average TAT value of 2.56 days.

  11. [Similarities and differences in absorption characteristics and composition of CDOM between Taihu Lake and Chaohu Lake].

    PubMed

    Shi, Kun; Li, Yun-mei; Wang, Qiao; Yang, Yu; Jin, Xin; Wang, Yan-fei; Zhang, Hong; Yin, Bin

    2010-05-01

    Field experiments are conducted separately in Taihu Lake and Chaohu Lake on Apr. and Jun. 2009. The changes in absorption spectra of chromophoric dissolved organic matter (CDOM) characteristics are analyzed using spectral differential analysis technology. According the spectral differential characteristic of absorption coefficient; absorption coefficient from 240 to 450 nm is divided into different stages, and the value of spectral slope S is calculated in each stage. In Stage A, S value of CDOM in Taihu Lake and Chaohu Lake are 0.0166-0.0102 nm(-1) [average (0.0132 +/- 0.0017) nm(-1)], 0.029-0.017 nm(-1) [average (0.0214 +/- 0.0024) nm(-1)]. In Stage B, S values are 0.0187-0.0148 nm(-1) [average (0.0169 +/- 0.001) nm(-1)], 0.0179-0.0055 nm(-1) [average (0.0148 +/- 0.002) nm(-1)]. In Stage C, S values are 0.0208-0.0164 nm(-1) [average (0.0186 +/- 0.0009) nm(-1)], 0.0253-0.0161 nm(-1) [average (0.0197 +/- 0.002) nm(-1)]. The results can be concluded as: (1) Absorption coefficient of water in Taihu Lake, and its contribution to absorption of each component is less than that of water in Chaohu Lake, however the standardized absorption coefficient is larger than that in Chaohu Lake. (2) Both in Taihu Lake and Chaohu Lake, derivative spectra of CDOM absorption coefficient reached valley at 260nm, then rise to top at 290 nm, CDOM absorption coefficient can be delivered into three stages. (3) Generally speaking, content of CDOM in Taihu Lake is less than in Chaohu Lake. (4) pectrum slope (S value) of CDOM is related to composition of CDOM, when content of humic acid in CDOM gets higher, S value of Stage B is the most sensitive value, then is the S value of Stage C. Oppositely, S value of Stage B gets the most sensitive value, then is the S value of Stage A; the least sensitive value is in Stage B.

  12. Study on relationship of nitric oxide, oxidation, peroxidation, lipoperoxidation with chronic chole-cystitis

    PubMed Central

    Zhou, Jun-Fu; Cai, Dong; Zhu, You-Gen; Yang, Jin-Lu; Peng, Cheng-Hong; Yu, Yang-Hai

    2000-01-01

    AIM: To study relationship of injury induced by nitric oxide, oxidation, peroxidation, lipoperoxidation with chronic cholecystitis. METHODS: The values of plasma nitric oxide (P-NO), plasma vitamin C (P-VC), plasma vitamin E (P-VE), plasma β-carotene (P-β-CAR), plasma lipoperoxides (P-LPO), erythrocyte superoxide dismutase (E-SOD), erythrocyte catalase (E-CAT), erythrocyte glutathione peroxidase (E-GSH-Px) activities and erythrocyte lipoperoxides (E-LPO) level in 77 patients with chro nic cholecystitis and 80 healthy control subjects were determined, differences of the above average values between t he patient group and the control group and differences of the average values bet ween preoperative and postoperative patients were analyzed and compared, linear regression and correlation of the disease course with the above determination values as well as the stepwise regression and correlation of the course with th e values were analyzed. RESULTS: Compared with the control group, the average values of P-NO, P-LPO, E-LPO were significantly increased (P < 0.01), and of P-VC, P-VE, P-β-CAR, E-SOD, E-CAT and E-GSH-Px decreased (P < 0.01) in the patient group. The analysis of the lin ear regression and correlation s howed that with prolonging of the course, the values of P-NO, P-LPO and E-LPO in the patients were gradually ascended and the values of P-VC, P-VE, P-β-CAR, E-SOD, E-CAT and E-GSH-Px descended (P < 0.01). The analysis of the stepwise regression and correlation indicated that the correlation of the course with P-NO, P-VE and P-β-CAR values was the closest. Compared with the preoperative patients, the average values of P-NO, P-LPO and E-LPO were significantly decre ased (P < 0.01) and the average values of P-VC, E-SOD, E-CAT and E-GSH-Px in postoperative pa tients increased (P < 0.01) in postoperative patients. But there was no signif icant difference in the average values of P-VE, P-β-CAR preope rative and postoperative patients. CONCLUSION: Chronic cholecystitis could induce the increase of nitric oxide, oxidation, peroxidation and lipoperoxidation. PMID:11819637

  13. Measuring radio-signal power accurately

    NASA Technical Reports Server (NTRS)

    Goldstein, R. M.; Newton, J. W.; Winkelstein, R. A.

    1979-01-01

    Absolute value of signal power in weak radio signals is determined by computer-aided measurements. Equipment operates by averaging received signal over several-minute period and comparing average value with noise level of receiver previously calibrated.

  14. Relating illness complexity to reimbursement in CKD patients.

    PubMed

    Bessette, Russell W; Carter, Randy L

    2011-01-01

    Despite significant investments of federal and state dollars to transition patient medical records to an all-electronic system, a chasm still exists between health care quality and payment for it. A major reason for this gap is the difficulty in evaluating health care outcomes based on claims data. Since both payers and patients may not appreciate how illness complexity impacts treatment outcomes, it is difficult to determine fair provider compensation. Chronic kidney disease (CKD) typifies these problems and is often associated with comorbidities that impact cost, health, and work productivity. Thus, the objective of this study was to evaluate an illness complexity score (ICS) based on a linear regression of select blood values that might assist in predicting average monthly reimbursements in CKD patients. A second objective was to compare the results of this ICS prediction to results obtained by prediction of average monthly reimbursement using CKD stage. A third objective was to analyze the relationship between the change in ICS, estimated glomerular filtration rate (eGFR), and CKD stage over time to average monthly reimbursement. We calculated parsimonious values for select variables associated with CKD patients and compared the ICS to ordinal staging of renal disease. Data from 177 de-identified patients over 13 months was collected, which included 15 blood chemistry observations along with complete claims data for all medical expenses. To test for the relationship between average blood chemistry values, stages of CKD, age, and average monthly reimbursement, we modeled an association through a linear regression function of age, eGFR, and the Z-scores calculated from average monthly values of phosphorus, parathyroid hormone, glucose, hemoglobin, bicarbonate, albumin, creatinine, blood urea nitrogen, potassium, calcium, sodium, alkaline phosphatase, alanine aminotransferase, and white blood cells. The results of our study demonstrated that the association between average ICS values throughout the entire study period predicted average monthly reimbursements with an R(2) value of 0.41. Comparing that value to the association between the average CKD stage and average monthly reimbursement demonstrated an R(2) value of 0.08. Thus, ICS offers five times greater sensitivity over CKD staging as a measure of illness complexity. Sorting the patient population by changes in CKD stage or ICS over the entire study period revealed significant differences between the two scoring methods. Groups scored by ICS demonstrated greater sensitivity by capturing dysfunction in other organ systems and had a better association with reimbursement than groups scored by CKD staging.

  15. The Accuracy of Stated Energy Contents of Reduced-Energy, Commercially Prepared Foods

    PubMed Central

    Urban, Lorien E.; Dallal, Gerard E.; Robinson, Lisa M.; Ausman, Lynne M.; Saltzman, Edward; Roberts, Susan B.

    2010-01-01

    The accuracy of stated energy contents of reduced-energy restaurant foods and frozen meals purchased from supermarkets was evaluated. Measured energy values of 29 quick-serve and sit-down restaurant foods averaged 18% more than stated values, and measured energy values of 10 frozen meals purchased from supermarkets averaged 8% more than originally stated. These differences substantially exceeded laboratory measurement error but did not achieve statistical significance due to considerable variability in the degree of underreporting. Some individual restaurant items contained up to 200% of stated values and, in addition, free side dishes increased provided energy to an average of 245% of stated values for the entrees they accompanied. These findings suggest that stated energy contents of reduced-energy meals obtained from restaurants and supermarkets are not consistently accurate, and in this study averaged more than measured values, especially when free side dishes were taken into account. If widespread, this phenomenon could hamper efforts to self-monitor energy intake to control weight, and could also reduce the potential benefit of recent policy initiatives to disseminate information on food energy content at the point of purchase. PMID:20102837

  16. Isolation and characterization of novel microsatellite markers and their application for diversity assessment in cultivated groundnut (Arachis hypogaea)

    PubMed Central

    Cuc, Luu M; Mace, Emma S; Crouch, Jonathan H; Quang, Vu D; Long, Tran D; Varshney, Rajeev K

    2008-01-01

    Background Cultivated peanut or groundnut (Arachis hypogaea L.) is the fourth most important oilseed crop in the world, grown mainly in tropical, subtropical and warm temperate climates. Due to its origin through a single and recent polyploidization event, followed by successive selection during breeding efforts, cultivated groundnut has a limited genetic background. In such species, microsatellite or simple sequence repeat (SSR) markers are very informative and useful for breeding applications. The low level of polymorphism in cultivated germplasm, however, warrants a need of larger number of polymorphic microsatellite markers for cultivated groundnut. Results A microsatellite-enriched library was constructed from the genotype TMV2. Sequencing of 720 putative SSR-positive clones from a total of 3,072 provided 490 SSRs. 71.2% of these SSRs were perfect type, 13.1% were imperfect and 15.7% were compound. Among these SSRs, the GT/CA repeat motifs were the most common (37.6%) followed by GA/CT repeat motifs (25.9%). The primer pairs could be designed for a total of 170 SSRs and were optimized initially on two genotypes. 104 (61.2%) primer pairs yielded scorable amplicon and 46 (44.2%) primers showed polymorphism among 32 cultivated groundnut genotypes. The polymorphic SSR markers detected 2 to 5 alleles with an average of 2.44 per locus. The polymorphic information content (PIC) value for these markers varied from 0.12 to 0.75 with an average of 0.46. Based on 112 alleles obtained by 46 markers, a phenogram was constructed to understand the relationships among the 32 genotypes. Majority of the genotypes representing subspecies hypogaea were grouped together in one cluster, while the genotypes belonging to subspecies fastigiata were grouped mainly under two clusters. Conclusion Newly developed set of 104 markers extends the repertoire of SSR markers for cultivated groundnut. These markers showed a good level of PIC value in cultivated germplasm and therefore would be very useful for germplasm analysis, linkage mapping, diversity studies and phylogenetic relationships in cultivated groundnut as well as related Arachis species. PMID:18482440

  17. Corrective responses in human food intake identified from an analysis of 7-d food-intake records2

    PubMed Central

    Bray, George A; Flatt, Jean-Pierre; Volaufova, Julia; DeLany, James P; Champagne, Catherine M

    2009-01-01

    Background We tested the hypothesis that ad libitum food intake shows corrective responses over periods of 1–5 d. Design This was a prospective study of food intake in women. Methods Two methods, a weighed food intake and a measured food intake, were used to determine daily nutrient intake during 2 wk in 20 women. Energy expenditure with the use of doubly labeled water was done contemporaneously with the weighed food-intake record. The daily deviations in macronutrient and energy intake from the average 7-d values were compared with the deviations observed 1, 2, 3, 4, and 5 d later to estimate the corrective responses. Results Both methods of recording food intake gave similar patterns of macronutrient and total energy intakes and for deviations from average intakes. The intraindividual CVs for energy intake ranged from ±12% to ±47% with an average of ±25%. Reported energy intake was 85.5–95.0% of total energy expenditure determined by doubly labeled water. Significant corrective responses were observed in food intakes with a 3- to 4-d lag that disappeared when data were randomized within each subject. Conclusions Human beings show corrective responses to deviations from average energy and macronutrient intakes with a lag time of 3–4 d, but not 1–2 d. This suggests that short-term studies may fail to recognize important signals of food-intake regulation that operate over several days. These corrective responses probably play a crucial role in bringing about weight stability. PMID:19064509

  18. Monitoring surgical and medical outcomes: the Bernoulli cumulative SUM chart. A novel application to assess clinical interventions

    PubMed Central

    Leandro, G; Rolando, N; Gallus, G; Rolles, K; Burroughs, A

    2005-01-01

    Background: Monitoring clinical interventions is an increasing requirement in current clinical practice. The standard CUSUM (cumulative sum) charts are used for this purpose. However, they are difficult to use in terms of identifying the point at which outcomes begin to be outside recommended limits. Objective: To assess the Bernoulli CUSUM chart that permits not only a 100% inspection rate, but also the setting of average expected outcomes, maximum deviations from these, and false positive rates for the alarm signal to trigger. Methods: As a working example this study used 674 consecutive first liver transplant recipients. The expected one year mortality set at 24% from the European Liver Transplant Registry average. A standard CUSUM was compared with Bernoulli CUSUM: the control value mortality was therefore 24%, maximum accepted mortality 30%, and average number of observations to signal was 500—that is, likelihood of false positive alarm was 1:500. Results: The standard CUSUM showed an initial descending curve (nadir at patient 215) then progressively ascended indicating better performance. The Bernoulli CUSUM gave three alarm signals initially, with easily recognised breaks in the curve. There were no alarms signals after patient 143 indicating satisfactory performance within the criteria set. Conclusions: The Bernoulli CUSUM is more easily interpretable graphically and is more suitable for monitoring outcomes than the standard CUSUM chart. It only requires three parameters to be set to monitor any clinical intervention: the average expected outcome, the maximum deviation from this, and the rate of false positive alarm triggers. PMID:16210461

  19. Comparative statistical analysis of carcinogenic and non-carcinogenic effects of uranium in groundwater samples from different regions of Punjab, India.

    PubMed

    Saini, Komal; Singh, Parminder; Bajwa, Bikramjit Singh

    2016-12-01

    LED flourimeter has been used for microanalysis of uranium concentration in groundwater samples collected from six districts of South West (SW), West (W) and North East (NE) Punjab, India. Average value of uranium content in water samples of SW Punjab is observed to be higher than WHO, USEPA recommended safe limit of 30µgl -1 as well as AERB proposed limit of 60µgl -1 . Whereas, for W and NE region of Punjab, average level of uranium concentration was within AERB recommended limit of 60µgl -1 . Average value observed in SW Punjab is around 3-4 times the value observed in W Punjab, whereas its value is more than 17 times the average value observed in NE region of Punjab. Statistical analysis of carcinogenic as well as non carcinogenic risks due to uranium have been evaluated for each studied district. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Apollo-Soyuz survey of the extreme-ultraviolet/soft X-ray background

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stern, R.; Bowyer, S.

    1979-06-15

    The results of an extensive sky survey of the extreme-ultraviolet (EUV)/soft X-ray background are reported. The data were obtained with a telescope, designed and calibrated at the University of California at Berkeley, which observed EUV sources and the diffuse background as part of the Apollo-Soyuz mission in 1975 July. With a primary field of view of 2 /sup 0/.3 +- 0 /sup 0/.1 FWHM and four EUV bandpass filters (16--25, 20--73, 80--108, and 80--250 eV), the EUV telescope obtained useful background data for 21 sky points, 11 large angle scans, and an additional group of short observations of both types.more » Analysis of the data reveals an intense 80--108 eV diffuse flux of 4.0 +- 1.3 photons cm/sup -2/ sr/sup -1/ eV/sup -1/ (broad-band weighted average). This is roughly a factor of 10 higher than the corresponding 150--280 eV average intensity and confirms the earlier results of Cash, Malina, and Stern. Galactic contributions to the background intensity at still lower energies are most likely masked by large fluxes of geocoronal or interplanetary solar-scattered resonance radiation; however, we drive upper limits to the local galactic background of 2 x 10/sup 4/ and 6 x 10/sup 2/ photons cm/sup -2/ sr/sup -1/ eV/sup -1/ averaged over the 16--25 eV and 20--73 eV bands, respectively. The uniformity of the background flux is uncertain due to limitations in the statistical accuracy of the data; we discuss probable upper limits to any spatial anisotropy. No evidence is found for a correlation between the telescope count rate and Earth-based parameters (zenith angle, Sun angle, etc.) for E> or approx. =80 eV. Unlike some previous claims for the soft X-ray background, no simple dependence upon galactic latitude is seen.Fitting models of thermal emission to the Apollo-Soyuz data yields constraints on model parameters that are consistent for a limited range of temperatures with the EUV results of Cash, Malina, and Stern and the soft X-ray data of Burstein et al.« less

  1. SU-C-207-02: A Method to Estimate the Average Planar Dose From a C-Arm CBCT Acquisition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Supanich, MP

    2015-06-15

    Purpose: The planar average dose in a C-arm Cone Beam CT (CBCT) acquisition had been estimated in the past by averaging the four peripheral dose measurements in a CTDI phantom and then using the standard 2/3rds peripheral and 1/3 central CTDIw method (hereafter referred to as Dw). The accuracy of this assumption has not been investigated and the purpose of this work is to test the presumed relationship. Methods: Dose measurements were made in the central plane of two consecutively placed 16cm CTDI phantoms using a 0.6cc ionization chamber at each of the 4 peripheral dose bores and in themore » central dose bore for a C-arm CBCT protocol. The same setup was scanned with a circular cut-out of radiosensitive gafchromic film positioned between the two phantoms to capture the planar dose distribution. Calibration curves for color pixel value after scanning were generated from film strips irradiated at different known dose levels. The planar average dose for red and green pixel values was calculated by summing the dose values in the irradiated circular film cut out. Dw was calculated using the ionization chamber measurements and film dose values at the location of each of the dose bores. Results: The planar average dose using both the red and green pixel color calibration curves were within 10% agreement of the planar average dose estimated using the Dw method of film dose values at the bore locations. Additionally, an average of the planar average doses calculated using the red and green calibration curves differed from the ionization chamber Dw estimate by only 5%. Conclusion: The method of calculating the planar average dose at the central plane of a C-arm CBCT non-360 rotation by calculating Dw from peripheral and central dose bore measurements is a reasonable approach to estimating the planar average dose. Research Grant, Siemens AG.« less

  2. Parafoveal Target Detectability Reversal Predicted by Local Luminance and Contrast Gain Control

    NASA Technical Reports Server (NTRS)

    Ahumada, Albert J., Jr.; Beard, Bettina L.; Null, Cynthia H. (Technical Monitor)

    1996-01-01

    This project is part of a program to develop image discrimination models for the prediction of the detectability of objects in a range of backgrounds. We wanted to see if the models could predict parafoveal object detection as well as they predict detection in foveal vision. We also wanted to make our simplified models more general by local computation of luminance and contrast gain control. A signal image (0.78 x 0.17 deg) was made by subtracting a simulated airport runway scene background image (2.7 deg square) from the same scene containing an obstructing aircraft. Signal visibility contrast thresholds were measured in a fully crossed factorial design with three factors: eccentricity (0 deg or 4 deg), background (uniform or runway scene background), and fixed-pattern white noise contrast (0%, 5%, or 10%). Three experienced observers responded to three repetitions of 60 2IFC trials in each condition and thresholds were estimated by maximum likelihood probit analysis. In the fovea the average detection contrast threshold was 4 dB lower for the runway background than for the uniform background, but in the parafovea, the average threshold was 6 dB higher for the runway background than for the uniform background. This interaction was similar across the different noise levels and for all three observers. A likely reason for the runway background giving a lower threshold in the fovea is the low luminance near the signal in that scene. In our model, the local luminance computation is controlled by a spatial spread parameter. When this parameter and a corresponding parameter for the spatial spread of contrast gain were increased for the parafoveal predictions, the model predicts the interaction of background with eccentricity.

  3. The Nutrient Density of Snacks

    PubMed Central

    Hess, Julie; Rao, Goutham; Slavin, Joanne

    2017-01-01

    Background: Although Americans receive almost a quarter of their daily energy from snacks, snacking remains a poorly defined and understood eating occasion. However, there is little dietary guidance about choosing snacks. Families, clinicians, and researchers need a comprehensive approach to assessing their nutritional value. Objective: To quantify and compare the nutrient density of commonly consumed snacks by their overall nutrient profiles using the Nutrient-Rich Foods (NRF) Index 10.3. Methods: NRF Index scores were calculated for the top 3 selling products (based on 2014 market research data) in different snack categories. These NRF scores were averaged to provide an overall nutrient-density score for each category. Results: Based on NRF scores, yogurt (55.3), milk (52.5), and fruit (30.1) emerged as the most nutrient-dense snacks. Ice cream (−4.4), pies and cakes (−11.1), and carbonated soft drinks (−17.2) emerged as the most nutrient-poor snacks. Conclusions: The NRF Index is a useful tool for assessing the overall nutritional value of snacks based on nutrients to limit and nutrients to encourage. PMID:28491924

  4. A New Lebanese Medication Adherence Scale: Validation in Lebanese Hypertensive Adults

    PubMed Central

    Wakim, N.; Issa, C.; Kassem, B.; Abou Jaoude, L.; Saleh, N.

    2018-01-01

    Background A new Lebanese scale measuring medication adherence considered socioeconomic and cultural factors not taken into account by the eight-item Morisky Medication Adherence Scale (MMAS-8). Objectives were to validate the new adherence scale and its prediction of hypertension control, compared to MMAS-8, and to assess adherence rates and factors. Methodology A cross-sectional study, including 405 patients, was performed in outpatient cardiology clinics of three hospitals in Beirut. Blood pressure was measured, a questionnaire filled, and sodium intake estimated by a urine test. Logistic regression defined predictors of hypertension control and adherence. Results 54.9% had controlled hypertension. 82.4% were adherent by the new scale, which showed good internal consistency, adequate questions (KMO coefficient = 0.743), and four factors. It predicted hypertension control (OR = 1.217; p value = 0.003), unlike MMAS-8, but the scores were correlated (ICC average measure = 0.651; p value < 0.001). Stress and smoking predicted nonadherence. Conclusion This study elaborated a validated, practical, and useful tool measuring adherence to medications in Lebanese hypertensive patients. PMID:29887993

  5. The Nutrient Density of Snacks: A Comparison of Nutrient Profiles of Popular Snack Foods Using the Nutrient-Rich Foods Index.

    PubMed

    Hess, Julie; Rao, Goutham; Slavin, Joanne

    2017-01-01

    Background: Although Americans receive almost a quarter of their daily energy from snacks, snacking remains a poorly defined and understood eating occasion. However, there is little dietary guidance about choosing snacks. Families, clinicians, and researchers need a comprehensive approach to assessing their nutritional value. Objective: To quantify and compare the nutrient density of commonly consumed snacks by their overall nutrient profiles using the Nutrient-Rich Foods (NRF) Index 10.3. Methods: NRF Index scores were calculated for the top 3 selling products (based on 2014 market research data) in different snack categories. These NRF scores were averaged to provide an overall nutrient-density score for each category. Results: Based on NRF scores, yogurt (55.3), milk (52.5), and fruit (30.1) emerged as the most nutrient-dense snacks. Ice cream (-4.4), pies and cakes (-11.1), and carbonated soft drinks (-17.2) emerged as the most nutrient-poor snacks. Conclusions: The NRF Index is a useful tool for assessing the overall nutritional value of snacks based on nutrients to limit and nutrients to encourage.

  6. Increased longitudinal contractility and diastolic function at rest in well-trained amateur Marathon runners: a speckle tracking echocardiography study

    PubMed Central

    2014-01-01

    Background Regular physical activity reduces cardiovascular risk. There is concern that Marathon running might acutely damage the heart. It is unknown to what extent intensive physical endurance activity influences the cardiac mechanics at resting condition. Methods Eighty-four amateur marathon runners (43 women and 41 men) from Berlin-Brandenburg area who had completed at least one marathon previously underwent clinical examination and echocardiography at least 10 days before the Berlin Marathon at rest. Standard transthoracic echocardiography and 2D strain and strain rate analysis were performed. The 2D Strain and strain rate values were compared to previous published data of healthy untrained individuals. Results The average global longitudinal peak systolic strain of the left ventricle was -23 +/- 2% with peak systolic strain rate -1.39 +/- 0.21/s, early diastolic strain rate 2.0 +/- 0.40/s and late diastolic strain rate 1.21 +/- 0.31/s. These values are significantly higher compared to the previous published values of normal age-adjusted individuals. In addition, no age-related decline of longitudinal contractility in well-trained athletes was observed. Conclusions There is increased overall longitudinal myocardial contractility at rest in experienced endurance athletes compared to the published normal values in the literature indicating a preserved and even supra-normal contractility in the athletes. There is no age dependent decline of the longitudinal 2D Strain values. This underlines the beneficial effects of regular physical exercise even in advanced age. PMID:24571726

  7. Magnetic, geochemical characterization and health risk assessment of road dust in Xuanwei and Fuyuan, China.

    PubMed

    Tan, Zhengying; Lu, Senlin; Zhao, Hui; Kai, Xiao; Jiaxian, Peng; Win, Myat Sandar; Yu, Shang; Yonemochi, Shinich; Wang, Qingyue

    2018-01-19

    As an accumulation of solid organic and inorganic pollutant particles on outdoor ground surfaces, road dust is an important carrier of heavy metal contaminants and can be a valuable medium for characterizing urban environmental quality. Because the dusts can be an important source of atmospheric particles and take impact on human health, the aim of this study described in detail the mineralogical characteristics, morphology, and heavy metal content of road dust from Xuanwei and Fuyuan, locations with high lung cancer incidence. Our results show that the average concentrations of heavy metals in road dust were higher than their background values. Higher concentrations of heavy metals were found in the magnetic fractions (MFs) than in the non-magnetic fractions (NMFs). Magnetic measurements revealed high magnetic susceptibility values in the road dust samples, and the dominant magnetic carrier was magnetite. The magnetic grains were predominantly pseudo-single domain, multi-domain, and coarse-grained stable single domains (coarse SSD) in size. SEM/XRD analysis identified two groups of magnetic particles: spherules and angular/aggregate particles. Hazard index (HI) values for adults exposure to road dust samples, including MF, Bulk, and NMF, in both areas were lower or close to safe levels, while HI values for childhood exposure to magnetic fractions in both areas were very close or higher than safe levels. Cancer risks from road dust exposure in both areas were in the acceptable value range.

  8. Evaluation of mercury pollution in cultivated and wild plants from two small communities of the Tapajós gold mining reserve, Pará State, Brazil.

    PubMed

    Egler, Silvia G; Rodrigues-Filho, Saulo; Villas-Bôas, Roberto C; Beinhoff, Christian

    2006-09-01

    This study examines the total Hg contamination in soil and sediments, and the correlation between the total Hg concentration in soil and vegetables in two small scale gold mining areas, São Chico and Creporizinho, in the State of Para, Brazilian Amazon. Total Hg values for soil samples for both study areas are higher than region background values (ca. 0.15 mg/kg). At São Chico, mean values in soils samples are higher than at Creporizinho, but without significant differences at alpha<0.05 level. São Chico's aboveground produce samples possess significantly higher values for total Hg levels than samples from Creporizinho. Creporizinho's soil-root produce regression model were significant, and the slope negative. Creporizinho's soil-aboveground and root wild plants regression models were also significant, and the slopes positives. Although, aboveground:root ratios were >1 in all of São Chico's produce samples, soil-plant parts regression were not significant, and Hg uptake probably occurs through stomata by atmospheric mercury deposition. Wild plants aboveground:root ratios were <1 at both study areas, and soil-plant parts regressions were significant in samples of Creporizinho, suggesting that they function as an excluder. The average total contents of Hg in edible parts of produces were close to FAO/WHO/JECFA PTWI values in São Chico area, and much lower in Creporizinho. However, Hg inorganic small gastrointestinal absorption reduces its adverse health effects.

  9. Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments

    PubMed Central

    2012-01-01

    Background Because of the large volume of data and the intrinsic variation of data intensity observed in microarray experiments, different statistical methods have been used to systematically extract biological information and to quantify the associated uncertainty. The simplest method to identify differentially expressed genes is to evaluate the ratio of average intensities in two different conditions and consider all genes that differ by more than an arbitrary cut-off value to be differentially expressed. This filtering approach is not a statistical test and there is no associated value that can indicate the level of confidence in the designation of genes as differentially expressed or not differentially expressed. At the same time the fold change by itself provide valuable information and it is important to find unambiguous ways of using this information in expression data treatment. Results A new method of finding differentially expressed genes, called distributional fold change (DFC) test is introduced. The method is based on an analysis of the intensity distribution of all microarray probe sets mapped to a three dimensional feature space composed of average expression level, average difference of gene expression and total variance. The proposed method allows one to rank each feature based on the signal-to-noise ratio and to ascertain for each feature the confidence level and power for being differentially expressed. The performance of the new method was evaluated using the total and partial area under receiver operating curves and tested on 11 data sets from Gene Omnibus Database with independently verified differentially expressed genes and compared with the t-test and shrinkage t-test. Overall the DFC test performed the best – on average it had higher sensitivity and partial AUC and its elevation was most prominent in the low range of differentially expressed features, typical for formalin-fixed paraffin-embedded sample sets. Conclusions The distributional fold change test is an effective method for finding and ranking differentially expressed probesets on microarrays. The application of this test is advantageous to data sets using formalin-fixed paraffin-embedded samples or other systems where degradation effects diminish the applicability of correlation adjusted methods to the whole feature set. PMID:23122055

  10. Statistical-techniques-based computer-aided diagnosis (CAD) using texture feature analysis: application in computed tomography (CT) imaging to fatty liver disease

    NASA Astrophysics Data System (ADS)

    Chung, Woon-Kwan; Park, Hyong-Hu; Im, In-Chul; Lee, Jae-Seung; Goo, Eun-Hoe; Dong, Kyung-Rae

    2012-09-01

    This paper proposes a computer-aided diagnosis (CAD) system based on texture feature analysis and statistical wavelet transformation technology to diagnose fatty liver disease with computed tomography (CT) imaging. In the target image, a wavelet transformation was performed for each lesion area to set the region of analysis (ROA, window size: 50 × 50 pixels) and define the texture feature of a pixel. Based on the extracted texture feature values, six parameters (average gray level, average contrast, relative smoothness, skewness, uniformity, and entropy) were determined to calculate the recognition rate for a fatty liver. In addition, a multivariate analysis of the variance (MANOVA) method was used to perform a discriminant analysis to verify the significance of the extracted texture feature values and the recognition rate for a fatty liver. According to the results, each texture feature value was significant for a comparison of the recognition rate for a fatty liver ( p < 0.05). Furthermore, the F-value, which was used as a scale for the difference in recognition rates, was highest in the average gray level, relatively high in the skewness and the entropy, and relatively low in the uniformity, the relative smoothness and the average contrast. The recognition rate for a fatty liver had the same scale as that for the F-value, showing 100% (average gray level) at the maximum and 80% (average contrast) at the minimum. Therefore, the recognition rate is believed to be a useful clinical value for the automatic detection and computer-aided diagnosis (CAD) using the texture feature value. Nevertheless, further study on various diseases and singular diseases will be needed in the future.

  11. Prevalence and characteristics of atherosclerosis and peripheral arterial disease in a Chinese population of Inner Mongolia.

    PubMed

    Wang, Y; Li, J; Zhao, D; Wei, Y; Hou, L; Hu, D; Xu, Y

    2011-01-01

    To investigate the relationship between brachial ankle pulse wave velocity (BaPWV), radial augmentation index (radial AI), ankle-brachial index (ABI), and carotid intima-media thickness (carotid-IMT), and to study the prevalence and characteristics of atherosclerosis and peripheral arterial disease in a Chinese population of Inner Mongolia. Participants were recruited from Inner Mongolia in China through cluster multistage and random sampling. BaPWV, radial AI, ABI, and carotid-IMT values were measured in each subject. A total of 1,236 participants from natural population of Inner Mongolia in China were included in this study. The average ABI value was 1.082 ± 0.093. The average values of common carotid, internal carotid, and carotid artery bifurcation IMT were 0.70 ± 0.21, 0.77 ± 0.24, and 0.78 ± 0.25 mm, respectively. The average value of BaPWV was 1450.5 ± 301.5 cm/s. The average value of radial AI was 78.9 ± 16.8 %. BaPWV, radial AI, and carotid-IMT values were positively correlated with ages significantly. BaPWV values were positively correlated with radial AI significantly. BaPWV values were positively correlated with values of common carotid, internal carotid, and carotid artery bifurcation IMT respectively. Radial AI values were positively correlated with the values of common carotid, internal carotid, and carotid artery bifurcation IMT respectively. A U-shaped relationship was observed that radial AI values were decreased at first and then increased as ABI values increased. The data suggests that BaPWV, radial AI, and carotid-IMT values are positively correlated with each other, and AI values are correlated with ABI values in a U-shaped curve in a Chinese population of Inner Mongolia.

  12. Validity of mini-dose gallium for objective quantification of alveolitis in pulmonary sarcoidosis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vitti, R.; Maurer, A.H.; Siegel, J.A.

    1985-05-01

    Patents (pts) with pulmonary sarcoidosis will often have frequent gallium (Ga) studies to assess the response of alveolitis to corticosteroid therapy. Since many pts are young and the cumulative radiation burden significant the authors have evaluated the ability of computer based Ga lung imaging to reliably quantify Ga activity using a 0.5 mCi dose of Ga. Twelve pts with biopsy proven pulmonary sarcoidosis received 0.5 mCi of Ga-67 citrate intravenously and had a posterior view of the chest including a portion of the liver obtained at 24 hrs post injection. At 24 hrs the pts received an additional 2.5 mCimore » and were then imaged at 48 and 72 hrs. A gallium score (GS) was computer generated as follows: regions of interest (ROI's) were manually created for the lungs, liver and background. Following a 9 point spatial smooth and background subtraction, the images were scaled so that the liver activity was assigned an arbitrary value of 400 counts per pixel. The resulting average counts per pixel for the lungs were then summed for the GS. Using a paired T-test there was only a borderline significant difference (0.05« less

  13. Distribution and enrichment of heavy metals in Sabratha coastal sediments, Mediterranean Sea, Libya

    NASA Astrophysics Data System (ADS)

    Nour, Hamdy E.; El-Sorogy, Abdelbaset S.

    2017-10-01

    In order to assess heavy metal pollutants in Sabratha coastal sediments, Mediterranean Sea, Libya, 30 sediment samples were collected for Fe, Cu, Pb, Mn, Cd, Co, Ni and Zn analysis using Atomic Absorption Spectrometry. The analysis indicated that, the Sabratha 's coastal sediments were enriched with Cd, Pb, Cu, Ni, Co and Zn (EF = 81.48, 17.26, 12.80, 11.42, 9.85 and 8.56 respectively). The highest levels of Mn, Cu, Ni, Pb and Co were recorded nearby the Mellitah complex oil and gas station in the western Libyan region, while the highest levels of Zn and Cd were recorded at the central part of the study area nearby fishing port and Sabratha hospital. Average values of Cd, Pb and Co were mostly higher than the ones recorded from the Arabian and Oman gulfs, the Red Sea, the Gulf of Aqaba, the Caspian Sea, coast of Tanzania and the background shale and the earth's crust. The high levels of most of the studied heavy metals suggested significant anthropogenic sources along Sabratha coast. The results of the present study provide a useful background for further marine studies on the Mediterranean area.

  14. C-FSCV: Compressive Fast-Scan Cyclic Voltammetry for Brain Dopamine Recording.

    PubMed

    Zamani, Hossein; Bahrami, Hamid Reza; Chalwadi, Preeti; Garris, Paul A; Mohseni, Pedram

    2018-01-01

    This paper presents a novel compressive sensing framework for recording brain dopamine levels with fast-scan cyclic voltammetry (FSCV) at a carbon-fiber microelectrode. Termed compressive FSCV (C-FSCV), this approach compressively samples the measured total current in each FSCV scan and performs basic FSCV processing steps, e.g., background current averaging and subtraction, directly with compressed measurements. The resulting background-subtracted faradaic currents, which are shown to have a block-sparse representation in the discrete cosine transform domain, are next reconstructed from their compressively sampled counterparts with the block sparse Bayesian learning algorithm. Using a previously recorded dopamine dataset, consisting of electrically evoked signals recorded in the dorsal striatum of an anesthetized rat, the C-FSCV framework is shown to be efficacious in compressing and reconstructing brain dopamine dynamics and associated voltammograms with high fidelity (correlation coefficient, ), while achieving compression ratio, CR, values as high as ~ 5. Moreover, using another set of dopamine data recorded 5 minutes after administration of amphetamine (AMPH) to an ambulatory rat, C-FSCV once again compresses (CR = 5) and reconstructs the temporal pattern of dopamine release with high fidelity ( ), leading to a true-positive rate of 96.4% in detecting AMPH-induced dopamine transients.

  15. Characterizing the mammography technologist workforce in North Carolina

    PubMed Central

    Henderson, Louise M.; Marsh, Mary W.; Benefield, Thad; Pearsall, Elizabeth; Durham, Danielle; Schroeder, Bruce F.; Bowling, J. Michael; Viglione, Cheryl A.; Yankaskas, Bonnie C.

    2016-01-01

    Background Mammography technologists’ level of training, years of experience, and feedback on technique may play an important role in the breast cancer screening process. However, very little information on the mammography technologist workforce exists. Methods In 2013, we conducted a mailed survey to 912 mammography technologists working in 224 Mammography Quality Standards Act accredited facilities in North Carolina. Using standard survey methodology we developed and implemented a questionnaire focused on the education and training, work experiences, and workplace interactions of mammography technologists. We aggregated responses using survey weights to account for non-response. We describe and compare lead (administrative responsibilities) and non-lead (supervised by another technologist) mammography technologist characteristics, testing for differences using t-tests and chi-square tests. Results A total of 433 mammography technologists responded (survey response rate=47.5%; 95% confidence interval:44.2%-50.7%), including 128 lead and 305 non-lead technologists. Most mammography technologists were non-Hispanic, white, females and the average age was 48 years. Approximately 93% of lead and non-lead technologists had mammography specific training but <4% had sonography certification and 3% had MRI certification. Lead technologists reported more years performing screening mammography (p-value=0.02) and film mammography (p-value=0.03), more administrative hours (p-value<0.0001), and more workplace autonomy (p-value=0.002) than non-lead technologists. Non-lead technologists were more likely to report performing diagnostic mammograms (p-value=0.0004) or other breast imaging (p-value=0.001), discuss image quality with a peer (p-value=0.013), and have frequent face-to-face interaction with radiologists (p-value=0.03). Conclusion Our findings offer insights into mammography technologists’ training and work experiences, highlighting variability in technologist characteristics between lead and non-lead technologists. PMID:26614888

  16. On the impacts of computing daily temperatures as the average of the daily minimum and maximum temperatures

    NASA Astrophysics Data System (ADS)

    Villarini, Gabriele; Khouakhi, Abdou; Cunningham, Evan

    2017-12-01

    Daily temperature values are generally computed as the average of the daily minimum and maximum observations, which can lead to biases in the estimation of daily averaged values. This study examines the impacts of these biases on the calculation of climatology and trends in temperature extremes at 409 sites in North America with at least 25 years of complete hourly records. Our results show that the calculation of daily temperature based on the average of minimum and maximum daily readings leads to an overestimation of the daily values of 10+ % when focusing on extremes and values above (below) high (low) thresholds. Moreover, the effects of the data processing method on trend estimation are generally small, even though the use of the daily minimum and maximum readings reduces the power of trend detection ( 5-10% fewer trends detected in comparison with the reference data).

  17. Exploring patient values in medical decision making: a qualitative study.

    PubMed

    Lee, Yew Kong; Low, Wah Yun; Ng, Chirk Jenn

    2013-01-01

    Patient decisions are influenced by their personal values. However, there is a lack of clarity and attention on the concept of patient values in the clinical context despite clear emphasis on patient values in evidence-based medicine and shared decision making. The aim of the study was to explore the concept of patient values in the context of making decisions about insulin initiation among people with type 2 diabetes. We conducted individual in-depth interviews with people with type 2 diabetes who were making decisions about insulin treatment. Participants were selected purposively to achieve maximum variation. A semi-structured topic guide was used to guide the interviews which were audio-recorded and analysed using a thematic approach. We interviewed 21 participants between January 2011 and March 2012. The age range of participants was 28-67 years old. Our sample comprised 9 women and 12 men. Three main themes, 'treatment-specific values', 'life goals and philosophies', and 'personal and social background', emerged from the analysis. The patients reported a variety of insulin-specific values, which were negative and/or positive beliefs about insulin. They framed insulin according to their priorities and philosophies in life. Patients' decisions were influenced by sociocultural (e.g. religious background) and personal backgrounds (e.g. family situations). This study highlighted the need for expanding the current concept of patient values in medical decision making. Clinicians should address more than just values related to treatment options. Patient values should include patients' priorities, life philosophy and their background. Current decision support tools, such as patient decision aids, should consider these new dimensions when clarifying patient values.

  18. 40 CFR 86.1862-04 - Maintenance of records and submittal of information relevant to compliance with fleet average NOX...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Control of Air Pollution From New and In-Use Light-Duty Vehicles, Light-Duty Trucks, and Complete Otto... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... NOX value achieved; and (iv) All values used in calculating the fleet average NOX value achieved. (2...

  19. 40 CFR 86.1862-04 - Maintenance of records and submittal of information relevant to compliance with fleet average NOX...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Control of Air Pollution From New and In-Use Light-Duty Vehicles, Light-Duty Trucks, and Complete Otto... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... NOX value achieved; and (iv) All values used in calculating the fleet average NOX value achieved. (2...

  20. 40 CFR 86.1862-04 - Maintenance of records and submittal of information relevant to compliance with fleet average NOX...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Control of Air Pollution From New and In-Use Light-Duty Vehicles, Light-Duty Trucks, and Complete Otto... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... NOX value achieved; and (iv) All values used in calculating the fleet average NOX value achieved. (2...

  1. 40 CFR 86.1862-04 - Maintenance of records and submittal of information relevant to compliance with fleet average NOX...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Control of Air Pollution From New and In-Use Light-Duty Vehicles, Light-Duty Trucks, and Complete Otto... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... NOX value achieved; and (iv) All values used in calculating the fleet average NOX value achieved. (2...

  2. Improving the Transition of Care in Patients Transferred Through the Ochsner Medical Center Transfer Center

    PubMed Central

    Amedee, Ronald G.; Maronge, Genevieve F.; Pinsky, William W.

    2012-01-01

    Background Patient transfers from other hospitals within the Ochsner Health System to the main campus are coordinated through a Transfer Center that was established in fall 2008. We analyzed the transfer process to assess distinct opportunities to enhance the overall transition of patient care. Methods We surveyed internal medicine residents and nocturnists to determine their satisfaction with transfers in terms of safety, efficiency, and usefulness of information provided at the time of transfer. After a kaizen event at which complementary goals for the institution and members of the study team were recognized and implemented, we resurveyed the group to evaluate improvement in the transfer process. Results The preintervention average satisfaction score was 1.18 (SD=0.46), while the postintervention score was 3.7 (SD=1.01). A t test showed a significant difference in the average scores between the preintervention and postintervention surveys (P<0.0001). Conclusions By including residents in the transfer calls (a result of the kaizen event), data were collected that facilitated fewer and higher quality handoffs that were performed in less time. In addition, the process resulted in increased awareness of the value of resident participation in institutional quality improvement projects. PMID:23267257

  3. A novel false color mapping model-based fusion method of visual and infrared images

    NASA Astrophysics Data System (ADS)

    Qi, Bin; Kun, Gao; Tian, Yue-xin; Zhu, Zhen-yu

    2013-12-01

    A fast and efficient image fusion method is presented to generate near-natural colors from panchromatic visual and thermal imaging sensors. Firstly, a set of daytime color reference images are analyzed and the false color mapping principle is proposed according to human's visual and emotional habits. That is, object colors should remain invariant after color mapping operations, differences between infrared and visual images should be enhanced and the background color should be consistent with the main scene content. Then a novel nonlinear color mapping model is given by introducing the geometric average value of the input visual and infrared image gray and the weighted average algorithm. To determine the control parameters in the mapping model, the boundary conditions are listed according to the mapping principle above. Fusion experiments show that the new fusion method can achieve the near-natural appearance of the fused image, and has the features of enhancing color contrasts and highlighting the infrared brilliant objects when comparing with the traditional TNO algorithm. Moreover, it owns the low complexity and is easy to realize real-time processing. So it is quite suitable for the nighttime imaging apparatus.

  4. Monitoring and assessment of radionuclide discharges from Temelín Nuclear Power Plant into the Vltava River (Czech Republic).

    PubMed

    Hanslík, Eduard; Ivanovová, Diana; Juranová, Eva; Simonek, Pavel; Jedináková-Krízová, Vĕra

    2009-02-01

    The paper summarizes impacts of the Temelín Nuclear Power Plant (NPP) on the Vltava and Labe River basins. The study is based on the results of long-term monitoring carried out before the plant operation (1989-2000), and subsequently during the plant operation (2001-2005). In the first period, the main objective was to determine background radionuclide levels remaining in the environment after global fallout and due to the Chernobyl accident. A decrease in the concentrations of (90)Sr, (134)Cs and (137)Cs, which was observed before the plant operation, continued also during the subsequent period. Apart from tritium, the results of the observation did not indicate any impacts of the plant on the concentrations of activation and fission products in the hydrosphere. The annual average tritium concentrations in the Vltava River were in agreement with predicted values. The maximum annual average tritium concentration (13.5 Bq L(-1)) was observed in 2004 downstream from the wastewater discharge in the Vltava River at Solenice. Estimated radiation doses for adults due to intakes of river water as drinking water contaminated by tritium are below 0.1 microSv y(-1).

  5. Liver hanging maneuver for right hemiliver in situ donation – anatomical considerations

    PubMed Central

    Gadžijev, E.M.; Ravnik, D.; Hribernik, M.

    2006-01-01

    Background. An anatomical study was carried out to evaluate the safety of the liver hanging maneuver for the right hemiliver in living donor and in situ splitting transplantation. During this procedure a 4–6 cm blind dissection is performed between the inferior vena cava and the liver. Short subhepatic veins entering the inferior vena cava from segments 1 and 9 could be torn with consequent hemorrhage. Materials and methods. One hundred corrosive casts of livers were evaluated to establish the position and diameter of short subhepatic veins and the inferior right hepatic vein. Results. The average distance from the right border of the inferior vena cava to the opening of segment 1 veins was 16.7±3.4 mm and to the entrance of segment 9 veins was 5.0±0.5 mm. The width of the narrowest point on the route of blind dissection was determined, with the average value being 8.7±2.3 mm (range 2–15 mm). Discussion. The results show that the liver hanging maneuver is a safe procedure. A proposed route of dissection minimizes the risk of disrupting short subhepatic veins (7%). PMID:18333236

  6. The analysis of corneal asphericity (Q value) and its related factors of 1,683 Chinese eyes older than 30 years.

    PubMed

    Xiong, Ying; Li, Jing; Wang, Ningli; Liu, Xue; Wang, Zhao; Tsai, Frank F; Wan, Xiuhua

    2017-01-01

    To determine corneal Q value and its related factors in Chinese subjects older than 30 years. Cross sectional study. 1,683 participants (1,683 eyes) from the Handan Eye Study were involved, including 955 female and 728 male with average age of 53.64 years old (range from 30 to 107 years). The corneal Q values of anterior and posterior surfaces were measured at 3.0, 5.0 and 7.0mm aperture diameters using Bausch & Lomb Orbscan IIz (software version 3.12). Age, gender and refractive power were recorded. The average Q values of the anterior surface at 3.0, 5.0 and 7.0mm aperture diameters were -0.28±0.18, -0.28±0.18, and -0.29±0.18, respectively. The average Q value of the anterior surface at the 5.0mm aperture diameter was negatively correlated with age (B = -0.003, p<0.01) and the refractive power (B = -0.013, p = 0.016). The average Q values of the posterior surface at 3.0, 5.0, and 7.0mm were -0.26±0.216, -0.26±0.214, and -0.26±0.215, respectively. The average Q value of the posterior surface at the 5.0mm aperture diameter was positively correlated with age (B = 0.002, p = 0.036) and the refractive power (B = 0.016, p = 0.043). The corneal Q value of the elderly Chinese subjects is different from that of previously reported European and American subjects, and the Q value appears to be correlated with age and refractive power.

  7. Improved simulation of group averaged CO2 surface concentrations using GEOS-Chem and fluxes from VEGAS

    NASA Astrophysics Data System (ADS)

    Chen, Z. H.; Zhu, J.; Zeng, N.

    2013-01-01

    CO2 measurements have been combined with simulated CO2 distributions from a transport model in order to produce the optimal estimates of CO2 surface fluxes in inverse modeling. However one persistent problem in using model-observation comparisons for this goal relates to the issue of compatibility. Observations at a single site reflect all underlying processes of various scales that usually cannot be fully resolved by model simulations at the grid points nearest the site due to lack of spatial or temporal resolution or missing processes in models. In this article we group site observations of multiple stations according to atmospheric mixing regimes and surface characteristics. The group averaged values of CO2 concentration from model simulations and observations are used to evaluate the regional model results. Using the group averaged measurements of CO2 reduces the noise of individual stations. The difference of group averaged values between observation and modeled results reflects the uncertainties of the large scale flux in the region where the grouped stations are. We compared the group averaged values between model results with two biospheric fluxes from the model Carnegie-Ames-Stanford-Approach (CASA) and VEgetation-Global-Atmosphere-Soil (VEGAS) and observations to evaluate the regional model results. Results show that the modeling group averaged values of CO2 concentrations in all regions with fluxes from VEGAS have significant improvements for most regions. There is still large difference between two model results and observations for grouped average values in North Atlantic, Indian Ocean, and South Pacific Tropics. This implies possible large uncertainties in the fluxes there.

  8. The effects of noise in cardiac diffusion tensor imaging and the benefits of averaging complex data.

    PubMed

    Scott, Andrew D; Nielles-Vallespin, Sonia; Ferreira, Pedro F; McGill, Laura-Ann; Pennell, Dudley J; Firmin, David N

    2016-05-01

    There is growing interest in cardiac diffusion tensor imaging (cDTI), but, unlike other diffusion MRI applications, there has been little investigation of the effects of noise on the parameters typically derived. One method of mitigating noise floor effects when there are multiple image averages, as in cDTI, is to average the complex rather than the magnitude data, but the phase contains contributions from bulk motion, which must be removed first. The effects of noise on the mean diffusivity (MD), fractional anisotropy (FA), helical angle (HA) and absolute secondary eigenvector angle (E2A) were simulated with various diffusion weightings (b values). The effect of averaging complex versus magnitude images was investigated. In vivo cDTI was performed in 10 healthy subjects with b = 500, 1000, 1500 and 2000 s/mm(2). A technique for removing the motion-induced component of the image phase present in vivo was implemented by subtracting a low-resolution copy of the phase from the original images before averaging the complex images. MD, FA, E2A and the transmural gradient in HA were compared for un-averaged, magnitude- and complex-averaged reconstructions. Simulations demonstrated an over-estimation of FA and MD at low b values and an under-estimation at high b values. The transition is relatively signal-to-noise ratio (SNR) independent and occurs at a higher b value for FA (b = 1000-1250 s/mm(2)) than MD (b ≈ 250 s/mm(2)). E2A is under-estimated at low and high b values with a transition at b ≈ 1000 s/mm(2), whereas the bias in HA is comparatively small. The under-estimation of FA and MD at high b values is caused by noise floor effects, which can be mitigated by averaging the complex data. Understanding the parameters of interest and the effects of noise informs the selection of the optimal b values. When complex data are available, they should be used to maximise the benefit from the acquisition of multiple averages. The combination of complex data is also a valuable step towards segmented acquisitions. Copyright © 2016 John Wiley & Sons, Ltd.

  9. Stable nitrogen isotope ratios and accumulation of PCDD/F and PCB in Baltic aquatic food chains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Broman, D.; Naef, C.; Rolff, C.

    Ratios of naturally occurring stable isotopes of nitrogen ({delta}{sup 15}N) can be used to numerically classify trophic levels of organisms in food chains. By combining analyses results of PCDD/Fs and non-ortho PCBs the biomagnification of these substances can be quantitatively estimated. The two Baltic food chains studied were one pelagic (phytoplankton -- settling particulate matter (SPM) -- zooplankton -- mysids -- herring -- cod) and one littoral (phytoplankton -- SPM -- blue mussel -- eider duck). The {delta}{sup 15}N-data gave food chain descriptions qualitatively consistent with previous conceptions of trophic arrangements in the food chains. Phytoplankton showed the lowest averagemore » {delta}{sup 15}N-value and the juvenile eider duck and the cod showed the highest average {delta}{sup 15}N-values for the littoral and pelagic food chains, respectively. The PCDD/Fs and PCBs concentrations were plotted versus the {delta}{sup 15}N-values for the different trophic levels and an exponential model of the form e{sup (A + B*{delta}N)} was fitted to the data. The estimates of the constant B in the model allows for an estimation of a biomagnification power (B) of different singular, or groups of, contaminants. A B-value around zero indicates that a substance is flowing through the food chain without being magnified, whereas a value > 0 indicates that a substance is biomagnified. Negative B-values indicate that a substance is not taken up or is metabolized. The A-term of the expression is only a scaling factor depending on the background level of the contaminant.« less

  10. One-dimensional analysis of the rate of plasma-assisted sputter deposition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Palmero, A.; Rudolph, H.; Habraken, F. H. P. M.

    2007-04-15

    In this article a recently developed model [A. Palmero, H. Rudolph, and F. H. P. M. Habraken, Appl. Phys. Lett. 89, 211501 (2006)] is applied to analyze the transport of sputtered material from the cathode toward the growing film when using a plasma-assisted sputtering deposition technique. The argon pressure dependence of the deposition rate of aluminum, silicon, vanadium, chromium, germanium, tantalum, and tungsten under several different experimental conditions has been analyzed by fitting experimental results from the literature to the above-mentioned theory. Good fits are obtained. Three quantities are deduced from the fit: the temperature of the cathode and ofmore » the growing film, and the value of the effective cross section for thermalization due to elastic scattering of a sputtered particle on background gas atoms. The values derived from the fits for the growing film and cathode temperature are very similar to those experimentally determined and reported in the literature. The effective cross sections have been found to be approximately the corresponding geometrical cross section divided by the average number of collisions required for the thermalization, implying that the real and effective thermalization lengths have a similar value. Finally, the values of the throw distance appearing in the Keller-Simmons model, as well as its dependence on the deposition conditions have been understood invoking the values of the cathode and film temperature, as well as of the value of the effective cross section. The analysis shows the overall validity of this model for the transport of sputtered particles in sputter deposition.« less

  11. Exposure to particles from laser printers operating within office workplaces.

    PubMed

    McGarry, Peter; Morawska, Lidia; He, Congrong; Jayaratne, Rohan; Falk, Matthew; Tran, Quang; Wang, Hao

    2011-08-01

    While recent research has provided valuable information as to the composition of laser printer particles, their formation mechanisms, and explained why some printers are emitters while others are low emitters, questions relating to the potential exposure of office workers remained unanswered. In particular, (i) what impact does the operation of laser printers have on the background particle number concentration (PNC) of an office environment over the duration of a typical working day? (ii) What is the airborne particle exposure to office workers in the vicinity of laser printers? (iii) What influence does the office ventilation have upon the transport and concentration of particles? (iv) Is there a need to control the generation of, and/or transport of particles arising from the operation of laser printers within an office environment? (v) What instrumentation and methodology is relevant for characterizing such particles within an office location? We present experimental evidence on printer temporal and spatial PNC during the operation of 107 laser printers within open plan offices of five buildings. The 8 h time-weighted average printer particle exposure is significantly less than the 8 h time-weighted local background particle exposure, but that peak printer particle exposure can be greater than 2 orders of magnitude higher than local background particle exposure. The particle size range is predominantly ultrafine (<100 nm diameter). In addition we have established that office workers are constantly exposed to nonprinter derived particle concentrations, with up to an order of magnitude difference in such exposure among offices, and propose that such exposure be controlled along with exposure to printer derived particles. We also propose, for the first time, that peak particle reference values be calculated for each office area analogous to the criteria used in Australia and elsewhere for evaluating exposure excursion above occupational hazardous chemical exposure standards. A universal peak particle reference value of 2.0 × 10(4) particles cm(-3) has been proposed.

  12. The influence of socio-cultural background and product value in usability testing.

    PubMed

    Sonderegger, Andreas; Sauer, Juergen

    2013-05-01

    This article examines the influence of socio-cultural background and product value on different outcomes of usability tests. A study was conducted in two different socio-cultural regions, Switzerland and East Germany, which differed in a number of aspects (e.g. economic power, price sensitivity and culture). Product value (high vs. low) was varied by manipulating the price of the product. Sixty-four test participants were asked to carry out five typical user tasks in the context of coffee machine usage, measuring performance, perceived usability, and emotion. The results showed that in Switzerland, high-value products were rated higher in usability than low-value products whereas in East Germany, high-value products were evaluated lower in usability. A similar interaction effect of socio-cultural background and product value was observed for user emotion. Implications are that the outcomes of usability tests do not allow for a simple transfer across cultures and that the mediating influence of perceived product value needs to be taken into consideration. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  13. A Catalog of Soft X-Ray Shadows, and More Contemplation of the 1/4 KeV Background

    NASA Technical Reports Server (NTRS)

    Snowden, S. L.; Freyberg, M. J.; Kuntz, K. D.; Sanders, W. T.

    1999-01-01

    This paper presents a catalog of shadows in the 1/4 keV soft X-ray diffuse background 4 (SXRB) that were identified by a comparison between ROSAT All-Sky Survey maps and DIRB&corrected IRAS 100 micron maps. These "shadows" are the negative correlations between the surface brightness of the SXRB and the column density of the Galactic interstellar medium (ISIM) over limited angular regions (a few degrees in extent). We have compiled an extensive but not exhaustive set of 378 shadows in the polar regions of the Galaxy (Absolute value (beta) > and approximately equal 20 deg.), and determined their foreground and background X-ray intensities (relative to the absorbing features), and the respective hardness ratios of that emission. The portion of the sky that was examined to find these shadows was restricted in general to regions where the minimum column density is less than and approximately equal to 4 x 10(exp 20) H/square cm, i.e., relatively high Galactic latitudes, and to regions away from distinct extended features in the SXRB such as supernova remnants and superbubbles. The results for the foreground intensities agree well with the recent results of a general analysis of the local 1/4 KeV emission while the background intensities show additional. but not unexpected scatter. The results also confirm the existence of a gradient in the hardness of the local 1/4 keV emission along a Galactic center/ anticenter axis with a temperature that varies from 10(exp 6.13) K to 10(exp 6.02) K, respectively. The average temperature of the foreground component from this analysis is 10(exp 6.08) K, compared to 10(exp 6.06) K in the previous analysis. Likewise, the average temperature for the distant component for the current and previous analyses are 10(exp 6.06) K and 10(exp 6.02) K, respectively. Finally, the results for the 1/4 keV halo emission are compared to the observed fluxes at 3/4 keV, where the lack of correlation suggests that the Galactic halo's 1/4 keV and 3/4 keV fluxes are likely produced by separate emission regions.

  14. Technical Note: Multipurpose CT, ultrasound, and MRI breast phantom for use in radiotherapy and minimally invasive interventions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruschin, Mark, E-mail: Mark.Ruschin@sunnybrook.ca; Chin, Lee; Ravi, Ananth

    Purpose: To develop a multipurpose gel-based breast phantom consisting of a simulated tumor with realistic imaging properties in CT, ultrasound and MRI, or a postsurgical cavity on CT. Applications for the phantom include: deformable image registration (DIR) quality assurance (QA), autosegmentation validation, and localization testing and training for minimally invasive image-guided procedures such as those involving catheter or needle insertion. Methods: A thermoplastic mask of a typical breast patient lying supine was generated and then filled to make an array of phantoms. The background simulated breast tissue consisted of 32.4 g each of ballistic gelatin (BG) powder and Metamusil™ (MM)more » dissolved in 800 ml of water. Simulated tumors were added using the following recipe: 12 g of barium sulfate (1.4% v/v) plus 0.000 14 g copper sulfate plus 0.7 g of MM plus 7.2 g of BG all dissolved in 75 ml of water. The phantom was evaluated quantitatively in CT by comparing Hounsfield units (HUs) with actual breast tissue. For ultrasound and MRI, the phantoms were assessed based on subjective image quality and signal-difference to noise (SDNR) ratio, respectively. The stiffness of the phantom was evaluated based on ultrasound elastography measurements to yield an average Young’s modulus. In addition, subjective tactile assessment of phantom was performed under needle insertion. Results: The simulated breast tissue had a mean background value of 24 HU on CT imaging, which more closely resembles fibroglandular tissue (40 HU) as opposed to adipose (−100 HU). The tumor had a mean CT number of 45 HU, which yielded a qualitatively realistic image contrast relative to the background either as an intact tumor or postsurgical cavity. The tumor appeared qualitatively realistic on ultrasound images, exhibiting hypoechoic characteristics compared to background. On MRI, the tumor exhibited a SDNR of 3.7. The average Young’s modulus was computed to be 15.8 ± 0.7 kPa (1 SD). Conclusions: We have developed a process to efficiently and inexpensively produce multipurpose breast phantoms containing simulated tumors visible on CT, ultrasound, and MRI. The phantoms have been evaluated for image quality and elasticity and can serve as a medium for DIR QA, autosegmentation QA, and training for minimally invasive procedures.« less

  15. Effect of an angular trajectory kick in a high-gain free-electron laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baxevanis, Panagiotis; Huang, Zhirong; Stupakov, Gennady

    In a free-electron laser, a transverse momentum offset (or “kick”) results in an oscillation of the centroid of the electron beam about the undulator axis. Studying the influence of this effect on the free-electron laser (FEL) interaction is important both from a tolerance point of view and for its potential diagnostic applications. In this paper, we present a self-consistent theoretical analysis of a high-gain FEL driven by such a “kicked” beam. In particular, we derive a solution to the three-dimensional, linearized initial value problem of the FEL through an orthogonal expansion technique and also describe a variational method for calculatingmore » the average FEL growth rate. Lastly, our results are benchmarked with genesis simulations and provide a robust theoretical background for a comparison with previous analytical results.« less

  16. Effect of an angular trajectory kick in a high-gain free-electron laser

    DOE PAGES

    Baxevanis, Panagiotis; Huang, Zhirong; Stupakov, Gennady

    2017-04-18

    In a free-electron laser, a transverse momentum offset (or “kick”) results in an oscillation of the centroid of the electron beam about the undulator axis. Studying the influence of this effect on the free-electron laser (FEL) interaction is important both from a tolerance point of view and for its potential diagnostic applications. In this paper, we present a self-consistent theoretical analysis of a high-gain FEL driven by such a “kicked” beam. In particular, we derive a solution to the three-dimensional, linearized initial value problem of the FEL through an orthogonal expansion technique and also describe a variational method for calculatingmore » the average FEL growth rate. Lastly, our results are benchmarked with genesis simulations and provide a robust theoretical background for a comparison with previous analytical results.« less

  17. Analysis of physical composition and heavy metals pollution of municipal solid waste (MSW) in Beijing

    NASA Astrophysics Data System (ADS)

    Zhang, H. B.; Zhang, H. Y.; Wang, G. Q.; Bai, X. J.

    2018-03-01

    By using on-site sampling and physical-chemical analysis, the physical composition and the contents of heavy metals in Beijing MSW were researched. The result showed that the main components of MSW in Beijing are mainly kitchen waste, the average content of kitchen waste are more than 60% and 50% in summer and in winter, respectively. The pollution of Cu, Hg and Cr are all more serious for MSW in Haidian and Dongcheng district. The heavy metal pollution of MSW in summer is higher than that in winter in Beijing. Seasonal impacts should be taken into consideration when dealing with MSW. The content of heavy metals in MSW exceeded the background value of soil in Haidian and Dongcheng districts. In order to reduce heavy metal pollution, the MSW should be separated collection and treated.

  18. An ecological risk assessment of heavy metal contamination in the surface sediments of Bosten Lake, northwest China.

    PubMed

    Mamat, Zulpiya; Haximu, Sadiguli; Zhang, Zhao Yong; Aji, Rouzi

    2016-04-01

    Bosten Lake, a typical rump lake in an oasis in northwest China, was chosen to evaluate the distribution, sources, pollution status, and potential ecological risk of heavy metals. Sediment samples were collected from the lake, and results showed that the values of the eight heavy metals all fell within the Second Soil National Standard, while the average and maximum values of the metals were higher than the background values of the study. Multivariate statistical analysis showed that sediment concentrations of Cd, Pb, Hg, and Zn were mainly influenced by man sources. In comparison, Cu, Ni, Cr, and As were primarily natural in origin. Enrichment factor analysis (EF) and the geo-accumulation index evaluation method (I geo) showed that Cd, Hg, and Pb fell under low and partial serious pollution levels, while Zn, As, Cr, Ni, and Cu mainly were characterized under no pollution and low pollution levels. The potential ecological hazards index (RI) showed that among the eight heavy metals, Pb, Hg, and Cd posed the highest potential ecological risk, with potential ecological hazards indices (RI) of 29.06, 27.71, and 21.54 %, respectively. These findings demonstrated that recent economic development in the area of the basin has led to heavy metal accumulation in the surface sediments of the lake.

  19. SAM 2 measurements of the polar stratospheric aerosol. Volume 9: October 1982 - April 1983

    NASA Technical Reports Server (NTRS)

    Mcmaster, L. R.; Powell, K. A.

    1991-01-01

    The Stratospheric Aerosol Measurement (SAM) II sensor aboard Nimbus 7 is providing 1.0 micron extinction measurements of Antarctic and Arctic stratospheric aerosols with a vertical resolution of 1 km. Representative examples and weekly averages including corresponding temperature profiles provided by NOAA for the time and place of each SAM II measurement are presented. Contours of aerosol extinction as a function of altitude and longitude or time are plotted, and aerosol optical depths are calculated for each week. Typical values of aerosol extinction and stratospheric optical depth in the Arctic are unusually large due to the presence of material from the El Chichon volcano eruption in the Spring of 1982. For example, the optical depth peaked at 0.068, more than 50 times background values. Typical values of aerosol extinction and stratospheric optical depth in the Antarctic varied considerably during this period due to the transport and arrival of the material from the El Chichon eruption. For example, the stratospheric optical depth varied from 0.002 in October 1982, to 0.021 in January 1983. Polar stratospheric clouds were observed during the Arctic winter, as expected. A representative sample is provided of the ninth 6-month period of data to be used in atmospheric and climatic studies.

  20. Assessment of trace metal contamination in stream sediments of the Tuul River, Mongolia

    NASA Astrophysics Data System (ADS)

    Dalai, B.

    2011-12-01

    Thirty four sediment samples were collected in Ulaanbaatar basin, along the Tuul River which is the main source of water for the capital city Ulaanbaatar, Mongolia. The catchment can be divided three parts (upper, middle, and lower) according to the extent of urbanization. The upper part of the river basin is comparatively less affected by human activity and it can be represent the natural background condition. The middle part is the urban area of Ulaanbaatar and lower part extends SW of the end of the urban area mostly used for agriculture and farming activity. The present study focused on the levels of potentially toxic metals such as As, Pb, Zn, Cu, Ni and Cr in order to assess the extent of environmental pollution and to discuss the origin of these contaminants in sediments of the Tuul River using X-ray fluorescence analyses. Metal concentrations in the sediments are discussed by comparison with average Upper Continental Crust values (UCC) and ecological risk assessment by reference to sediment quality guidelines (SQG). The results showed thet average abundances of metals are measurable contrast between upper, middle and lower parts of the river. The Upper part and its surrounding area's sediment signature indicated that more depletion comparatively other parts (Pb, Zn, Cu, Ni and Cr), whereas enrichment sign did not detect. However, among the Upper part sediments, two samples (NA1 and NA2) enriched with trace metals which sampled from Nalaikh area were significantly affected by coal mining activity. Most metals are (As, Pb, Zn, Cu and Ni) higher in the middle part (within the city) than the upper and lower part due to the urban activities. The small tributaries such as Selbe, Uliastai, Gachuurt and Tolgoit were significantly affected by urban activities and highest values are detected from them. Lower part significantly enriched with Cr (av 98 ppm). Highest concentration of Cr (183 ppm) was at Shuvuu which is receiving point of domestic and industrial wastewater discharge. However all three parts show depletion in some chalcophile and HFSE elements (Cu, Ni, Cr, Sr, Nb, Zr, Th, Sc). This depletion of elements relative to UCC suggest that the river sediments were derived from a highly felsic crustal source. The assessment of ecological risk assessment result showed that adverse aquatic biological effects caused by As and Cr. While, concentration of Pb, Zn, Cu and Ni are generally below their respective Threshold effect level (TEL), in middle part reaches to reach values bordering on the Probable effect level (PEL). This indicated that anthropogenic contribution in the urban areas, increasing values above a naturally low regional background.

  1. Dynamic Testing and Test Anxiety amongst Gifted and Average-Ability Children

    ERIC Educational Resources Information Center

    Vogelaar, Bart; Bakker, Merel; Elliott, Julian G.; Resing, Wilma C. M.

    2017-01-01

    Background: Dynamic testing has been proposed as a testing approach that is less disadvantageous for children who may be potentially subject to bias when undertaking conventional assessments. For example, those who encounter high levels of test anxiety, or who are unfamiliar with standardized test procedures, may fail to demonstrate their true…

  2. 1980 Survey of Faculty Teaching in Departments of Medicinal/Pharmaceutical Chemistry at American Colleges of Pharmacy.

    ERIC Educational Resources Information Center

    Matuszak, Alice Jean; Sarnoff, Darwin

    1981-01-01

    An American Association of Colleges of Pharmacy survey of medicinal/pharmaceutical chemistry faculty is reported. Data, including academic and experience backgrounds of faculty and their teaching load, are presented. Differences in training are noted in comparing the average chemistry professor to the average assistant professor. (Author/MLW)

  3. Investigation of natural effective gamma dose rates case study: Ardebil Province in Iran

    PubMed Central

    2012-01-01

    Gamma rays pose enough energy to induce chemical changes that may be biologically important for the normal functioning of body cells. The external exposure of human beings to natural environmental gamma radiation normally exceeds that from all man-made sources combined. In this research natural background gamma dose rates and corresponding annual effective doses were determined for selected cities of Ardebil province. Outdoor gamma dose rates were measured using an Ion Chamber Survey Meter in 105 locations in selected districts. Average absorbed doses for Ardebil, Sar-Ein, Germy, Neer, Shourabil Recreational Lake, and Kosar were determined as 265, 219, 344, 233, 352, and 358 nSv/h, respectively. Although dose rates recorded for Germi and Kosar are comparable with some areas with high natural radiation background, however, the dose rates in other districts are well below the levels reported for such locations. Average annual effective dose due to indoor and outdoor gamma radiation for Ardebil province was estimated as 1.73 (1.35–2.39) mSv, which is on average 2 times higher than the world population weighted average. PMID:23369115

  4. Size-resolved aerosol and cloud condensation nuclei (CCN) properties in the remote marine South China Sea - Part 1: Observations and source classification

    NASA Astrophysics Data System (ADS)

    Atwood, Samuel A.; Reid, Jeffrey S.; Kreidenweis, Sonia M.; Blake, Donald R.; Jonsson, Haflidi H.; Lagrosas, Nofel D.; Xian, Peng; Reid, Elizabeth A.; Sessions, Walter R.; Simpas, James B.

    2017-01-01

    Ship-based measurements of aerosol and cloud condensation nuclei (CCN) properties are presented for 2 weeks of observations in remote marine regions of the South China Sea/East Sea during the southwestern monsoon (SWM) season. Smoke from extensive biomass burning throughout the Maritime Continent advected into this region during the SWM, where it was mixed with anthropogenic continental pollution and emissions from heavy shipping activities. Eight aerosol types were identified using a k-means cluster analysis with data from a size-resolved CCN characterization system. Interpretation of the clusters was supplemented by additional onboard aerosol and meteorological measurements, satellite, and model products for the region. A typical bimodal marine boundary layer background aerosol population was identified and observed mixing with accumulation mode aerosol from other sources, primarily smoke from fires in Borneo and Sumatra. Hygroscopicity was assessed using the κ parameter and was found to average 0.40 for samples dominated by aged accumulation mode smoke; 0.65 for accumulation mode marine aerosol; 0.60 in an anthropogenic aerosol plume; and 0.22 during a short period that was characterized by elevated levels of volatile organic compounds not associated with biomass burning impacts. As a special subset of the background marine aerosol, clean air masses substantially scrubbed of particles were observed following heavy precipitation or the passage of squall lines, with changes in observed aerosol properties occurring on the order of minutes. Average CN number concentrations, size distributions, and κ values are reported for each population type, along with CCN number concentrations for particles that activated at supersaturations between 0.14 and 0.85 %.

  5. Polychlorinated dibenzo-p-dioxins and dibenzofurans in the remote North Atlantic marine atmosphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baker, J.I.; Hites, R.A.

    1999-01-01

    The authors have developed a sampling strategy that allows them to determine femtogram/cubic mater concentrations of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) in remote marine atmospheres. Using this sampling strategy, a total of 37 air samples were taken during two extended sampling periods at Bermuda between September 1993 and August 1997. During this time, the average total PCDD/F concentrations at Bermuda decreased from 105 {+-} 30 to 35 {+-} 10 fg/m{sup 3}, giving a half-life of about 2 years for these compounds in the remote marine atmosphere. PCDD/F concentrations during both sampling periods were somewhat higher in the winter thenmore » air parcels originated from North America. A second air-sampling station was established at Barbados where 22 air samples were taken between March 1996 and August 1997; an average total PCDD/F concentration at Barbados of 15 {+-} 7 fg/m{sup 3} was found. This value was not significantly different than the 27 {+-} 7 fg/m{sup 3} found at Bermuda during this time when air arrived from the east. This indicated that the remote marine background concentration for these compounds is currently on the order of 20 fg/m{sup 3}. Using these background concentrations, the dry depositional rate of PCDD/F to the world`s oceans was estimated to be 200 {+-} 80 kg/year, and the wet depositional rate was estimated to be 900 {+-} 300 kg/year. This is a total deposition rate of about 1 t/year to the oceans as compared to their previous estimate of 12 t/year PCDD/F deposition from the atmosphere to the land.« less

  6. Heavy metals in estuarine surface sediments of the Hai River Basin, variation characteristics, chemical speciation and ecological risk.

    PubMed

    Lei, Pei; Zhang, Hong; Shan, Baoqing; Lv, Shucong; Tang, Wenzhong

    2016-04-01

    The Hai River Basin (HRB) is considered to be one of the most polluted areas in China due to the high regional population density and rapid economic development. The estuaries of the HRB, which receive pollutants from terrestrial rivers, may subsequently suffer potential pollution and result in ecological risk of heavy metals. Six heavy metals (Cd, Cr, Cu, Ni, Pb, and Zn) were measured in estuarine surface sediments from 10 estuaries of the HRB to investigate their variation characteristics and ecological risks. The spatial difference of Cr, Ni, Pb, and Zn in sediments was higher than that of the rest two elements. The Yongdingxin Estuary (YDX) and Ziyaxin Estuary (ZYX) in the Northern Hai River System (NHRS) were the most severe in terms of heavy metal contamination. According to the Risk Assessment Code (RAC) classification, Cd associated with the exchangeable and carbonate fraction (the average of 21.3 %) indicated medium risk to high risk. More than 50 % of Cr, Cu, Ni, and Zn on average were associated with the residual fraction. Based on the sum of the first three fractions (exchangeable and carbonate + reducible + oxidizable), the mobility order of these heavy metals was Cd >Pb > Zn ≈ Cu > Ni > Cr. Compared to the background values of cinnamon soil, the potential ecological risk index (RI) values ranged from 25.6 to 168, with an average of 91.2, indicating a low ecological risk in estuarine sites of the HRB. Cd and Pb were the dominant contributors to the toxic-response factor (45.8 and 25.5 %, respectively). The results give insight into the different control measures pertaining to heavy metal pollution and risk for both relatively clean estuaries and urban seriously polluted areas, respectively, for the formation of protect strategies of aquatic environment in the HRB.

  7. Value of Adult Volunteer Leaders in the New Mexico 4-H Program.

    ERIC Educational Resources Information Center

    Hutchins, Julie K.; Seevers, Brenda S.; Van Leeuwen, Dawn

    2002-01-01

    Using data from 187 New Mexico 4-H program volunteers, economic value of volunteer time was determined by calculating the average number of hours spent in 1 year and multiplying the number by the average hourly wage for nonagricultural workers. The data on volunteer activities and their value can be used for program planning, recruitment, and…

  8. 40 CFR 80.825 - How is the refinery or importer annual average toxics value determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... number of batches of gasoline produced or imported during the averaging period. i = Individual batch of... toxics value, Ti, of each batch of gasoline is determined using the Phase II Complex Model specified at...

  9. An Investigation of Language Environment Analysis Measures for Spanish-English Bilingual Preschoolers From Migrant Low-Socioeconomic-Status Backgrounds.

    PubMed

    Wood, Carla; Diehm, Emily A; Callender, Maya F

    2016-04-01

    The current study was designed to (a) describe average hourly Language Environment Analysis (LENA) data for preschool-age Spanish-English bilinguals (SEBs) and typically developing monolingual peers and (b) compare LENA data with mean length of utterance in words (MLUw) and total number of words (TNW) calculated on a selected sample of consecutive excerpts of audio files (CEAFs). Investigators examined average hourly child vocalizations from daylong LENA samples for 42 SEBs and 39 monolingual English-speaking preschoolers. The relationship between average hourly child vocalizations, conversational turns, and adult words from the daylong samples and MLUw from a 50-utterance CEAF was examined and compared between groups. MLUw, TNW, average hourly child vocalizations, and conversational turns were lower for young SEBs than monolingual English-speaking peers. Average hourly child vocalizations were not strongly related to MLUw performance for monolingual or SEB participants (r = .29, r = .25, respectively). In a similar manner, average hourly conversational turns were not strongly related to MLUw for either group (r = .22, r = .21, respectively). Young SEBs from socioeconomically disadvantaged backgrounds showed lower average performance on LENA measures, MLUw, and TNW than monolingual English-speaking peers. MLUw from monolinguals were also lower than typical expectations when derived from CEAFs. LENA technology may be a promising tool for communication sampling with SEBs; however, more research is needed to establish norms for interpreting MLUw and TNW from selected CEAF samples.

  10. Average of delta: a new quality control tool for clinical laboratories.

    PubMed

    Jones, Graham R D

    2016-01-01

    Average of normals is a tool used to control assay performance using the average of a series of results from patients' samples. Delta checking is a process of identifying errors in individual patient results by reviewing the difference from previous results of the same patient. This paper introduces a novel alternate approach, average of delta, which combines these concepts to use the average of a number of sequential delta values to identify changes in assay performance. Models for average of delta and average of normals were developed in a spreadsheet application. The model assessed the expected scatter of average of delta and average of normals functions and the effect of assay bias for different values of analytical imprecision and within- and between-subject biological variation and the number of samples included in the calculations. The final assessment was the number of patients' samples required to identify an added bias with 90% certainty. The model demonstrated that with larger numbers of delta values, the average of delta function was tighter (lower coefficient of variation). The optimal number of samples for bias detection with average of delta was likely to be between 5 and 20 for most settings and that average of delta outperformed average of normals when the within-subject biological variation was small relative to the between-subject variation. Average of delta provides a possible additional assay quality control tool which theoretical modelling predicts may be more valuable than average of normals for analytes where the group biological variation is wide compared with within-subject variation and where there is a high rate of repeat testing in the laboratory patient population. © The Author(s) 2015.

  11. Consistency of the structure of Legendre transform in thermodynamics with the Kolmogorov-Nagumo average

    NASA Astrophysics Data System (ADS)

    Scarfone, A. M.; Matsuzoe, H.; Wada, T.

    2016-09-01

    We show the robustness of the structure of Legendre transform in thermodynamics against the replacement of the standard linear average with the Kolmogorov-Nagumo nonlinear average to evaluate the expectation values of the macroscopic physical observables. The consequence of this statement is twofold: 1) the relationships between the expectation values and the corresponding Lagrange multipliers still hold in the present formalism; 2) the universality of the Gibbs equation as well as other thermodynamic relations are unaffected by the structure of the average used in the theory.

  12. Preliminary report on uranium deposits in the Miller Hill area, Carbon County, Wyoming

    USGS Publications Warehouse

    Love, J.D.

    1953-01-01

    A sequence of radioactive rocks of Miocene (?) age, the Browns Park formation, in the Miller Hill area of southern Wyoming is more than 1,000 feet thick. The formation crops out in an area of approximately 600 square miles, and consists of a basal conglomerate, tuffs, tuffaceous limy sandstones, and thin persistent radioactive algal limestones. Uranium is concentrated in both algal limestones and in tuffaceous limy sandstones. The uranium is believed to have been deposited. at least in part with the sediments, rather than to have come in at a later date. The highest uranium values were found in a widespread algal limestone bed, which contains as much as 0. 15 percent uranium. Values of 0.01 percent uranium or more were obtained from 8 samples taken from approximately 220 feet of stratigraphic section in the Browns Park formation. This is the first reported occurrence of limestone source rock from Wyoming that has been found to contain a commercial grade of uranium. The economic possibilities of the area have not been determined adequately and no estimates of tonnage are warranted at the present time. An airborne radiometric survey was made by the Geophysics Branch of the Geological Survey, of the west half of the area, recommended by the writer for investigation. Ground check of all anomalies reported at that time showed that they were in localities where the background radiation was much higher than average. Additional localities with high background radiation were found on the ground in the area east of that which was flown.

  13. Effects of calorie labeling and value size pricing on fast food meal choices: Results from an experimental trial

    PubMed Central

    Harnack, Lisa J; French, Simone A; Oakes, J Michael; Story, Mary T; Jeffery, Robert W; Rydell, Sarah A

    2008-01-01

    Background Although point-of-purchase calorie labeling at restaurants has been proposed as a strategy for improving consumer food choices, a limited number of studies have evaluated this approach. Likewise, little research has been conducted to evaluate the influence of value size pricing on restaurant meal choices. Methods To examine the effect of point-of-purchase calorie information and value size pricing on fast food meal choices a randomized 2 × 2 factorial experiment was conducted in which participants ordered a fast food meal from one of four menus that varied with respect to whether calorie information was provided and whether value size pricing was used. Study participants included 594 adolescents and adults who regularly ate at fast food restaurants. Study staff recorded the foods ordered and consumed by each participant. Participants also completed surveys to assess attitudes, beliefs and practices related to fast food and nutrition. Results No significant differences in the energy composition of meals ordered or eaten were found between menu conditions. The average energy content of meals ordered by those randomized to a menu that included calorie information and did not include value size pricing was 842 kcals compared with 827 kcals for those who ordered their meal from a menu that did not include calorie information but had value size pricing (control menu). Results were similar in most analyses conducted stratified by factors such as age, race and education level. Conclusion Additional research is needed to better evaluate the effects of calorie labeling and value size pricing on fast food meal choices. Studies in which participants are repeatedly exposed to these factors are needed since long term exposure may be required for behavior change. PMID:19061510

  14. How long the singular value decomposed entropy predicts the stock market? - Evidence from the Dow Jones Industrial Average Index

    NASA Astrophysics Data System (ADS)

    Gu, Rongbao; Shao, Yanmin

    2016-07-01

    In this paper, a new concept of multi-scales singular value decomposition entropy based on DCCA cross correlation analysis is proposed and its predictive power for the Dow Jones Industrial Average Index is studied. Using Granger causality analysis with different time scales, it is found that, the singular value decomposition entropy has predictive power for the Dow Jones Industrial Average Index for period less than one month, but not for more than one month. This shows how long the singular value decomposition entropy predicts the stock market that extends Caraiani's result obtained in Caraiani (2014). On the other hand, the result also shows an essential characteristic of stock market as a chaotic dynamic system.

  15. Deciphering Seasonal Variations of Diet and Water in Modern White-Tailed Deer by In Situ Analysis of Osteons in Cortical Bone

    NASA Astrophysics Data System (ADS)

    Larson, T. E.; Longstaffe, F. J.

    2004-12-01

    In situ stable carbon and oxygen isotope compositions of biogenic apatite were obtained from longitudinally-cut sections of cortical bone from femurs of modern domesticated sheep and free-range White-Tailed deer, using an IR-laser and a GC-continuous flow interface. Ablation pits averaged 200x50 microns, making it possible to analyze individual osteons. Since cortical bone is remodelled along osteons throughout a mammal's lifetime, isotopic data at this resolution provides information about seasonal variations in diet and drinking water. The O-isotope results were calibrated using laser analyses of NBS-18 and NBS-19, which produced a value of 26.39±0.46 permil (n=27) for WS-1 calcite (accepted value, 26.25 permil). C-isotope results were calibrated using a CO2 reference gas, producing a value of 0.76±0.40permil (n=27) for WS-1, also in excellent agreement with its accepted value of 0.74 permil. Average O- and C-isotope values for a local domestic sheep (southwestern Ontario, Canada) were 12.20±0.58 and -15.70±0.35 permil (n=27), respectively. No isotopic trend occurred along or across individual osteons. This pattern is consistent with the sheep's relatively unchanging food and water sources. The free-range White-Tailed deer came from Pinery Provincial Park (PPP), southwestern Ontario. Its O- and C-isotope compositions varied systematically across individual osteons and were negatively correlated (R2=0.56). O-isotope values ranged from 13.4 to 15.5 permil; the highest values correlated with summer and the lowest values, with winter. The O-isotope compositions of the main water source (Old Ausable River Channel) varied similarly during the deer's lifetime: winter average, -10.7±0.5 permil; summer average, -8.6±0.4 permil. The C-isotope results for the deer osteons varied from -19.7 to -15.9 permil. This variation can be explained by changes in food sources. Summer diets of deer in PPP consist mainly of leafy fractions of C3 vegetation, especially sumac, cedar, oak and pine (average leaf C-isotope value, -28.4±0.8 permil). During winter, when leafy material is unavailable and deep snow inhibits access to vegetation in general, deer strip bark from vegetation (average bark C-isotope value, -25.6±0.8 permil). Certain C4 grasses (little bluestem and sandreed grass, average C-isotope value, -12.7±0.2 permil), which are abundant in unforested dune areas of PPP, commonly stand above the snow cover, and hence are also available for consumption. Deer may also range more widely in the winter, feeding on corn stalks and husks that escaped both harvest and snow cover (average C-isotope value, -11.3±0.2 permil).

  16. Investigation of the Entrance Surface Dose and Dose to Different Organs in Lumbar Spine Imaging

    PubMed Central

    Sina, S; Zeinali, B; Karimipoorfard, M; Lotfalizadeh, F; Sadeghi, M; Zamani, E; Faghihi, R

    2014-01-01

    Background: Dose assessment using proper dosimeters is especially important in radiation protection optimization and imaging justification in diagnostic radiology. Objective: The aim of this study is to obtain the Entrance Skin Dose (ESD) of patients undergoing lumbar spine imaging using two thermoluminescence dosimeters TLD-100 (LiF: Mg, Ti) and GR-200 (LiF: Mg, Cu, P) and also to obtain the absorbed dose to different organs in lumbar spine imaging with several views. Methods: To measure the ESD values of the patients undergoing lumbar spine imaging, the two TLD types were put on their skin surface. The ESD values for different views of lumbar spine imaging were also measured by putting the TLDs at the surface of the Rando phantom. Several TLD chips were inserted inside different organs of Rando phantom to measure the absorbed dose to different organs in lumbar spine imaging. Results: The results indicate that there is a close agreement between the results of the two dosimeters. Based on the results of this experiment, the ESD dose of the 16 patients included in this study varied between 2.71 mGy and 26.29 mGy with the average of 11.89 mGy for TLD-100, and between 2.55 mGy and 27.41 mGy with the average of 12.32 mGy for GR-200 measurements. The ESDs obtained by putting the two types of TLDs at the surface of Rando phantom are in close agreement. Conclusion: According to the results, the GR200 has greater sensitivity than the TLD-100. PMID:25599058

  17. Aircraft measurements of SO2, NOx, CO, and O3 over the coastal and offshore area of Yellow Sea of China.

    PubMed

    Yang, Xiaoyang; Wang, Xinhua; Yang, Wen; Xu, Jun; Ren, Lihong; He, Youjiang; Liu, Bing; Bai, Zhipeng; Meng, Fan; Hu, Min

    2016-09-01

    In order to investigate long-range transport of the air pollution in the East Asia, air pollutants, including SO2, NOx, CO, and O3, were observed by aircraft measurement over the coastal and offshore area of Yellow Sea of China in April 2011. NOx and SO2 seemed to become moderate in recent years, and the concentrations during the whole observations ranged from 0.49 to 9.57 ppb and from 0.10 to 16.02 ppb, respectively. The high concentrations of CO were measured with an average value of 0.98 ppm. The measured O3 average concentration was 76.25 ppb, which showed a higher level comparing with the results from some previous studies. Most of the results for the concentration values generally followed the typical characteristic of vertical and spatial distribution, which were "low altitude > high altitude" and "land/coastal > sea," respectively. Transport of polluted air mass from the continent to the aircraft measurement area was confirmed in some days during the observation by the meteorological analysis, while the measurement results supposed to represent the background level of the pollutants in rest days. Additionally, some small-scale air pollution plumes were observed. Significant positive correlations between NOx and SO2 indicated that these two species originated from the same region. On the other hand, good positive correlations between NOx and O3 found during 2-day flight suggested that the O3 formation was probably under "NOx-limited" regime in these days.

  18. Safety Culture Assessment in Petrochemical Industry: A Comparative Study of Two Algerian Plants

    PubMed Central

    Boughaba, Assia; Hassane, Chabane; Roukia, Ouddai

    2014-01-01

    Background To elucidate the relationship between safety culture maturity and safety performance of a particular company. Methods To identify the factors that contribute to a safety culture, a survey questionnaire was created based mainly on the studies of Fernández-Muñiz et al. The survey was randomly distributed to 1000 employees of two oil companies and realized a rate of valid answer of 51%. Minitab 16 software was used and diverse tests, including the descriptive statistical analysis, factor analysis, reliability analysis, mean analysis, and correlation, were used for the analysis of data. Ten factors were extracted using the analysis of factor to represent safety culture and safety performance. Results The results of this study showed that the managers' commitment, training, incentives, communication, and employee involvement are the priority domains on which it is necessary to stress the effort of improvement, where they had all the descriptive average values lower than 3.0 at the level of Company B. Furthermore, the results also showed that the safety culture influences the safety performance of the company. Therefore, Company A with a good safety culture (the descriptive average values more than 4.0), is more successful than Company B in terms of accident rates. Conclusion The comparison between the two petrochemical plants of the group Sonatrach confirms these results in which Company A, the managers of which are English and Norwegian, distinguishes itself by the maturity of their safety culture has significantly higher evaluations than the company B, who is constituted of Algerian staff, in terms of safety management practices and safety performance. PMID:25180135

  19. Nonmedical prescription pain reliever and alcohol consumption among cannabis users

    PubMed Central

    Novak, Scott P.; Peiper, Nicholas C.; Zarkin, Gary A.

    2016-01-01

    Background This study examined poly-drug use involving the use of cannabis with nonmedical prescription pain reliever use (NMPR) and alcohol use. Methods Computer-assisted survey data from the National Survey on Drug Use and Health were examined. The NSDUH is an annual, cross-sectional survey of non-institutionalized citizens in the United States (ages 12+). Replicate analyses were conducted using the 2013 and 2003 survey waves. Results Higher levels of cannabis use were consistently associated with more frequent consumption of prescription pain relievers, with findings replicating in both 2013 and 2003. While the prevalence of dual users declined from 2003 (2.5%) to 2013 (2.3%), the average number of days used among dual users increased by an average of 20 days over that period. These changes largely occurred among those aged 35 or older, males, whites, and non-illicit drug users. Past-year marijuana use increased by 16% (10.8–12.6%, p-value < .001) whereas NMPR decreased by 15% (4.9–4.2%, p-value < .001). The largest changes occurred after 2011. Persons using the most cannabis generally had higher levels of alcohol use relative to those using the least amount of cannabis. There was a significant increase in the prevalence of dual use between 2003 (10.2%) and 2013 (11.6%), while the prevalence of past-year alcohol use remained relatively stable. Conclusions Clinical efforts and public health interventions should consider the possible co-ingestion of cannabis with NMPR and alcohol, as concomitant use may portend negative health effects in the short and long-term. PMID:26748409

  20. The application of "natural" growth rates of Heterostegina depressa to infer timing of reproduction events

    NASA Astrophysics Data System (ADS)

    Eder, Wolfgang; Julia, Woeger; Kinoshita, Shunichi; Hohenegger, Johann; Briguglio, Antonino

    2017-04-01

    To explore applicability of the natural laboratory approach (sensu Hohenegger) on population dynamic studies of recent larger benthic foraminifera, this relatively new experimental method has been applied on Heterostegina depressa populations from Sesoko Jima, NW Okinawa, Japan. It is used to gain an averaged chamber and diameter building rate, as well as the average longevity of H. depressa based on monthly samplings at fixed sampling stations. Samples were collected by SCUBA in 16 monthly intervals around 20 and 50 meters water depth, wherefrom live populations were dried and investigated by microCT. The specimens were measured regarding chamber number and maximum diameter. This biometric data has been tested for the presence of multiple generations of H. depressa megalospheres. In case of skewed or bimodal frequency distributions, they were decomposed into normally distributed components. Means and standard deviations of each component of every month were extracted and could be used to calculate the maximum values of chamber number and diameter for all sampling intervals. Based on these maximal values, the natural chamber/diameter growth rate was fitted by Michaelis-Menten functions. By inversion of this growth functions the birthdate of every specimen was calculated. Frequency diagrams of these dates reveal a continuous background reproduction throughout the year, yet show distinct reproduction peaks in late spring and late autumn. Further, sinusoidal regression analysis support these two main reproduction cycles, one short-term cycle 70 days and a one long-term cycles around 180 days. Surprisingly, similar cycles have been found in different studies on volumetric growth of larger benthic foraminifera.

  1. Management of background pain and anxiety in critically burned children requiring protracted mechanical ventilation.

    PubMed

    Sheridan, R; Stoddard, F; Querzoli, E

    2001-01-01

    Optimal control of pain and anxiety is an elusive but important goal in children with protracted critical illness. This review represents an effort to document the doses of background medication required to achieve this goal in a group of children managed under a pain and anxiety protocol that adjusts background infusions to comfort. The course of children with wounds involving at least 10% of the body surface and coincident respiratory failure requiring mechanical ventilation for more than 7 days managed 1 Jan 97 to 31 Dec 98 was reviewed. A pain and anxiety protocol was used, including background infusions of morphine and midazolam adjusted to comfort. These 28 children had a mean (+/- standard deviation) age of 5.3 +/- 4.6 years, wound size of 48.3 +/- 28.4%, and were intubated for 25.0 +/- 23.9 days. Neuromuscular blocking drugs were administered for 65 of 447 (14.5%) ventilator days. To maintain comfort, drugs were required at doses substantially above standard dosing schemes. The highest daily background infusion of morphine sulfate averaged 0.40 mg/kg/hr +/- 0.24 mg/kg/hr (usual starting dose was 0.05 to 0.1 mg/kg/hr) and was reached 14.1 +/- 12.8 days after admission. The highest daily background infusion of midazolam averaged 0.15 +/- 0.07 mg/kg/hr (usual starting dose was 0.04 mg/kg/hr) and was reached 14.0 +/- 3.8 days after admission. Morphine infusions at extubation averaged 0.22 +/- 0.17 mg/kg/hr and midazolam infusions 0.10 +/- 0.12 mg/kg/hr. All children survived to discharge and there was no perceived morbidity related to these high doses of medication. Children with serious burns and respiratory failure will require high doses of background opiates and benzodiazepines to remain comfortable, because they develop drug tolerance during protracted critical illness. Infusions can be continued at a reduced dose through extubation, do not result in addiction or other apparent morbidity if adjusted to desired level of comfort, and may contribute to a reduced incidence of treatment-related stress disorders.

  2. Air-surface exchange measurements of gaseous elemental mercury over naturally enriched and background terrestrial landscapes in Australia

    NASA Astrophysics Data System (ADS)

    Edwards, G. C.; Howard, D. A.

    2012-10-01

    This paper presents the first gaseous elemental mercury (GEM) air-surface exchange measurements obtained over naturally enriched and background (< 0.1 μg g-1 Hg) terrestrial landscapes in Australia. Two pilot field studies were carried out during the Australian autumn and winter periods at a copper-gold-cobalt-arsenic-mercury mineral field near Pulganbar, NSW. GEM fluxes using a dynamic flux chamber approach were measured, along with controlling environmental parameters over three naturally enriched and three background substrates. The enriched sites results showed net emission to the atmosphere and a strong correlation between flux and substrate Hg concentration, with average fluxes ranging from 14 ± 1 ng m-2 h-1 to 113 ± 6 ng m-2 h-1. Measurements at background sites showed both emission and deposition. The average Hg flux from all background sites showed an overall net emission of 0.36 ± 0.06 ng m-2 h-1. Fluxes show strong relationships with temperature, radiation, and substrate parameters. A compensation point of 2.48, representative of bare soils was determined. Comparison of the Australian data to North American data confirmed the need for Australian specific mercury air-surface exchange data representative of Australia's unique climatic conditions, vegetation types, land use patterns, and soils.

  3. Measurement of θ 13 in Double Chooz using neutron captures on hydrogen with novel background rejection techniques

    DOE PAGES

    Abe, Y.; Appel, S.; Abrahão, T.; ...

    2016-01-27

    We observed a measurement of the Double Chooz collaboration and the neutrino mixing angle θ 13 using reactormore » $$\\bar{v}$$ e via the inverse beta decay reaction in which the neutron is captured on hydrogen. Our measurement is based on 462.72 live days data, approximately twice as much data as in the previous such analysis, collected with a detector positioned at an average distance of 1050 m from two reactor cores. Several novel techniques have been developed to achieve significant reductions of the backgrounds and systematic uncertainties. Accidental coincidences, the dominant background in this analysis, are suppressed by more than an order of magnitude with respect to our previous publication by a multi-variate analysis. Furthermore, these improvements demonstrate the capability of precise measurement of reactor $$\\bar{v}$$ e without gadolinium loading. Spectral distortions from the $$\\bar{v}$$ e reactor flux predictions previously reported with the neutron capture on gadolinium events are confirmed in the independent data sample presented here. A value of sin 2 2θ 13= 0.095 0.039 +0.038 (stat+syst) is obtained from a fit to the observed event rate as a function of the reactor power, a method insensitive to the energy spectrum shape. A simultaneous fit of the hydrogen capture events and of the gadolinium capture events yields a measurement of sin 2 2θ 13 = 0.088 ± 0.033(stat+syst).« less

  4. Estimating the parameters of background selection and selective sweeps in Drosophila in the presence of gene conversion

    PubMed Central

    Campos, José Luis; Charlesworth, Brian

    2017-01-01

    We used whole-genome resequencing data from a population of Drosophila melanogaster to investigate the causes of the negative correlation between the within-population synonymous nucleotide site diversity (πS) of a gene and its degree of divergence from related species at nonsynonymous nucleotide sites (KA). By using the estimated distributions of mutational effects on fitness at nonsynonymous and UTR sites, we predicted the effects of background selection at sites within a gene on πS and found that these could account for only part of the observed correlation between πS and KA. We developed a model of the effects of selective sweeps that included gene conversion as well as crossing over. We used this model to estimate the average strength of selection on positively selected mutations in coding sequences and in UTRs, as well as the proportions of new mutations that are selectively advantageous. Genes with high levels of selective constraint on nonsynonymous sites were found to have lower strengths of positive selection and lower proportions of advantageous mutations than genes with low levels of constraint. Overall, background selection and selective sweeps within a typical gene reduce its synonymous diversity to ∼75% of its value in the absence of selection, with larger reductions for genes with high KA. Gene conversion has a major effect on the estimates of the parameters of positive selection, such that the estimated strength of selection on favorable mutations is greatly reduced if it is ignored. PMID:28559322

  5. [Telemetry data based on comparative study of physical activity in patients with resynchronization device].

    PubMed

    Melczer, Csaba; Melczer, László; Goják, Ilona; Kónyi, Attila; Szabados, Sándor; Raposa, L Bence; Oláh, András; Ács, Pongrác

    2017-05-01

    The effect of regular physical activity on health is widely recognized, but several studies have shown its key importance for heart patients. The present study aimed to define the PA % values, and to convert them into metabolic equivalent values (MET), which describes oxygen consumption during physical activity. A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.35 yrs ± 9.54; body mass 98.71 ± 9.89 kg; average BMI 36.69 ± 3.67 were recruited into the study. The measured values from Cardiac Resynchronisation Therapy devices and outer accelerometers (ActiGraph GT3X+) were studied over a 7-day time period. Using the two sets of values describing physical performance, linear regression was calculated providing a mathematical equation, thus, the Physical Activity values in percentage were converted into MET values. During the 6-minute walk test the patients achieved an average of 416.6 ± 48.2 m. During 6MWT the measured values averaged at 1.85 ± 0.18 MET's, and MET values averaged at 1.12 ± 0.06 per week. It clearly shows that this test is a challenge for the patients compared to their daily regular physical activity levels. With our method, based on the values received from the physical activity sensor implanted into the resynchronisation devices, changes in patients' health status could be monitored telemetrically with the assistance from the implanted electronic device. Orv Hetil. 2017; 158(17): 748-753.

  6. 21 CFR 610.62 - Proper name; package label; legible type.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) BIOLOGICS GENERAL BIOLOGICAL PRODUCTS STANDARDS Labeling Standards § 610.62 Proper name; package... contrast in color value between the proper name and the background shall be at least as great as the color value between the trademark and trade name and the background. Typography, layout, contrast, and other...

  7. Intergenerational family solidarity: value differences between immigrant groups and generations.

    PubMed

    Merz, Eva-Maria; Ozeke-Kocabas, Ezgi; Oort, Frans J; Schuengel, Carlo

    2009-06-01

    Although immigrants may be more dependent on their immediate family for support, they may also experience a wider generation-gap in values regarding intergenerational solidarity, because of processes of acculturation. Based on large scale survey data (N = 2,028), differences between first and second generation immigrants in values regarding intergenerational solidarity were examined among family members in the Netherlands with an immigration background from Turkey, Morocco, Suriname, and The Dutch Antilles. Using a multilevel analytic approach, effects of family and individual characteristics on values regarding intergenerational solidarity were tested, considering the perspectives of two generations. It was found that immigrants with Moroccan and Turkish backgrounds scored higher on values with respect to intergenerational family solidarity than immigrants stemming from Suriname and The Antilles. First generation immigrants placed higher values on family solidarity compared to second generation immigrants. Additionally, religious denomination was a significant predictor of higher values with respect to intergenerational family solidarity. Immigration and acculturation may create great strains in migrant families. Policies to support the fabric of intergenerational solidarity should consider ethnic and religious background and immigration history. Copyright 2009 APA, all rights reserved.

  8. Clinical Profile of Children and Adolescents Attending the Behavioural Paediatrics Unit OPD in a Tertiary Care Set up

    ERIC Educational Resources Information Center

    Jayaprakash, R.

    2012-01-01

    Background: There are limited studies on the clinical profile of children attending child guidance clinic under Paediatric background. Aims: To study clinical profile of Children & adolescents attending the Behavioural Paediatrics Unit (BPU) OPD under department of Paediatrics in a tertiary care set up. Methods: Monthly average turnover in the…

  9. Analyzing Patients' Values by Applying Cluster Analysis and LRFM Model in a Pediatric Dental Clinic in Taiwan

    PubMed Central

    Lin, Shih-Yen; Liu, Chih-Wei

    2014-01-01

    This study combines cluster analysis and LRFM (length, recency, frequency, and monetary) model in a pediatric dental clinic in Taiwan to analyze patients' values. A two-stage approach by self-organizing maps and K-means method is applied to segment 1,462 patients into twelve clusters. The average values of L, R, and F excluding monetary covered by national health insurance program are computed for each cluster. In addition, customer value matrix is used to analyze customer values of twelve clusters in terms of frequency and monetary. Customer relationship matrix considering length and recency is also applied to classify different types of customers from these twelve clusters. The results show that three clusters can be classified into loyal patients with L, R, and F values greater than the respective average L, R, and F values, while three clusters can be viewed as lost patients without any variable above the average values of L, R, and F. When different types of patients are identified, marketing strategies can be designed to meet different patients' needs. PMID:25045741

  10. Analyzing patients' values by applying cluster analysis and LRFM model in a pediatric dental clinic in Taiwan.

    PubMed

    Wu, Hsin-Hung; Lin, Shih-Yen; Liu, Chih-Wei

    2014-01-01

    This study combines cluster analysis and LRFM (length, recency, frequency, and monetary) model in a pediatric dental clinic in Taiwan to analyze patients' values. A two-stage approach by self-organizing maps and K-means method is applied to segment 1,462 patients into twelve clusters. The average values of L, R, and F excluding monetary covered by national health insurance program are computed for each cluster. In addition, customer value matrix is used to analyze customer values of twelve clusters in terms of frequency and monetary. Customer relationship matrix considering length and recency is also applied to classify different types of customers from these twelve clusters. The results show that three clusters can be classified into loyal patients with L, R, and F values greater than the respective average L, R, and F values, while three clusters can be viewed as lost patients without any variable above the average values of L, R, and F. When different types of patients are identified, marketing strategies can be designed to meet different patients' needs.

  11. Preliminary evaluation of magnitude and frequency of floods in selected small drainage basins in Ohio

    USGS Publications Warehouse

    Kolva, J.R.

    1985-01-01

    A previous study of flood magitudes and frequencies in Ohio concluded that existing regionalized flood equations may not be adequate for estimating peak flows in small basins that are heavily forested, surface mined, or located in northwestern Ohio. In order to provide a large data base for improving estimation of flood peaks in these basins, 30 crest-stage gages were installed in 1977, in cooperation with the Ohio Department of Transportation, to provide a 10-year record of flood data The study area consists of two distinct parts: Northwestern Ohio, which contains 8 sites, and southern and eastern Ohio, which contains 22 sites in small forested or surface-mined drainage basins. Basin characteristics were determined for all 30 sites for 1978 conditions. Annual peaks were recorded or estimated for all 30 sites for water years 1978-82; an additional year of peak discharges was available at four sites. The 2-year (Q2) and 5-year (Q5) flood peaks were determined from these annual peaks.Q2 and Q5 values also were calculated using published regionalized regression equations for Ohio. The ratios of the observed to predicted 2-year (R2) and 5-year (R5) values were then calculated. This study found that observed flood peaks aree lower than estimated peaks by a significant amount in surface-mined basins. The average ratios of observed to predicted R2 values are 0.51 for basins with more than 40 percent surface-minded land, and 0.68 for sites with any surface-mined land. The average R5 value is 0.55 for sites with more than 40 percent surface-minded land, and 0.61 for sites with any surface-mined land. Estimated flood peaks from forested basins agree with the observed values fairly well. R2 values average 0.87 for sites with 20 percent or more forested land, but no surface-mined land, and R5 values average 0.96. If all sites with more than 20 percent forested land and some surface-mined land are considered, R2 the values average 0.86, and the R5 values average 0.82.

  12. C3: The Compositional Construction of Context. A New, More Effective and Efficient Way to Marshal Inferences from Background Knowledge

    DTIC Science & Technology

    2014-09-01

    quarter. Deep natural language understanding , efficient inference, pragmatics, background knowledge U U U SAR 4 Dr. David McDonald (781) 718-1964 C3...effective and efficient way to marshal inferences from background knowledge ’ N00014-13-1-0228 Dr. David McDonald Smart Information Flow Technologies, dba...for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data

  13. Georgia fishery study: implications for dose calculations. Revision 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Turcotte, M.D.S.

    Fish consumption will contribute a major portion of the estimated individual and population doses from L-Reactor liquid releases and Cs-137 remobilization in Steel Creek. It is therefore important that the values for fish consumption used in dose calculations be as realistic as possible. Since publication of the L-Reactor Environmental Information Document (EID), data have become available on sport fishing in the Savannah River. These data provide SRP with a site-specific sport fish harvest and consumption values for use in dose calculations. The Georgia fishery data support the total population fish consumption and calculated dose reported in the EID. The datamore » indicate, however, that both the EID average and maximum individual fish consumption have been underestimated, although each to a different degree. The average fish consumption value used in the EID is approximately 3% below the lower limit of the fish consumption range calculated using the Georgia data. Maximum fish consumption in the EID has been underestimated by approximately 60%, and doses to the maximum individual should also be recalculated. Future dose calculations should utilize an average adult fish consumption value of 11.3 kg/yr, and a maximum adult fish consumption value of 34 kg/yr. Consumption values for the teen and child age groups should be increased proportionally: (1) teen average = 8.5; maximum = 25.9 kg/yr; and (2) child average = 3.6; maximum = 11.2 kg/yr. 8 refs.« less

  14. Average and Bright Adults with Parents with Mild Cognitive Difficulties: The Huck Finn Syndrome 20 Years Later

    ERIC Educational Resources Information Center

    O'Neill, Audrey Myerson

    2011-01-01

    Background: This longitudinal study of 20 average and bright adults with parents with cognitive difficulties follows a study 20 years earlier of their childhood adaptation to their parents. Method: Semistructured interviews about life situation and changes and perception of family-of-origin. Results: The participants' socioeconomic status changed…

  15. Evaluation of anthropogenic influence on thermodynamics, gas and aerosol composition of city air

    NASA Astrophysics Data System (ADS)

    Uzhegova, Nina; Belan, Boris; Antokhin, Pavel; Zhidovkhin, Evgenii; Ivlev, Georgii; Kozlov, Artem; Fofonov, Aleksandr

    2010-05-01

    In the last 40-50 years there is a global tendency of urbanisation, which is a consequence of most countries' economical development. Concurrently, the issue of environment's ecological state has become critical. Urban air pollution is among the most important ecological problems nowadays. World Health Organization (WHO) points out certain "classical" polluting agents: carbon monoxide (CO), nitric oxide (NO), nitrogen dioxide (NO2), sulphur dioxide (SO2), troposphere ozone (O3) (studied here), as well as lead, carbon dioxide (CO2), aldehydes, soot, benzpyrene and dredges (including dust, haze and smoke) [1]. An evaluation of antropogenic component's weight in the thermodynamical conditions and gas and aerosol composition of a city's atmosphere (by the example of Tomsk) is given in this paper. Tomsk is located at the South of West Siberia and is the administrative center of Tomsk region. The city's area is equal to 294,6 km2. Its population is 512.6 thousands of people. The overall number of registered motor vehicles in the city in 2008 was 131 700. That is, every fourth city inhabitant has a personal car. From 2002 to 2008 the number of motor vehicles in Tomsk has increased by 25 thousands units [2]. This increase consists mostly of passenger cars. There is also a positive trend in fuel consumtion by the city's industries and motor vehicles - from 2004 to 2007 it has increased by 10%. Such a quick rate of transport quantity's increase in the city provides reason to suggest an unfavorable ecological situation in Tomsk. For this study we have used the AKV-2 mobile station designed by the SB RAS Institute of Atmospheric Optics. The station's equipment provides the following measurements [3]: air temperature and humidity; aerosol disperse composition in 15 channels with a particle size range of 0.3-20 µm by use of the Grimm-1.108 aerosol spectrometer; NO, NO2, O3, SO2, CO, CO2 concentration. This paper describes a single experiment conducted in Tomsk. Date of experiment: Thursday, 14.05.2009. Local time: 15:00-17:30. Weather: clear, no precipitation. The measurements had been conducted on a "snake" route through the city including all of the main traffic arteries. Taking the wind rose into account, a background (clear) point had been selected for comparison with the city measurements. Temperature: The measurements have shown that air temperature in the city is higher than in suburbs by 1-1.5 оC on average. In the main traffic arteries the temperature difference between the city and suburbs (∆Т) is largest and reaches 3.19 оC. Absolute humidity: The measurements have shown that the absolute humidity in the city is higher than the background value by 2.5 g/m3 on average. This suggests an additional source of water vapor in the city. Taking into account that the area of maximum ∆А (3.16 g/m3) is located along one of the city's main streets, we can assume that the main source of water vapor in the city is automobile transport. Gas composition: Judging by gas composition, the area for background measurements had been chosen correctly. Daily average MPC for the main polluting agents (except for ozone) did not exceed the normal values. Opposite situation has been observed in the city. We have found out that the city is a "pollution island". Concentration of admixtures (NO, NO2, CO) in the city's center are considerably higher than in the background area. At the main traffic arteries daily average MPC has been considerably exceeded, as well as one-time MPC for certain pollution agents. Ozone concentration value in the city's atmosphere is inversely proportional to the nitric oxide concentration, because NO is involved in cycles leading to ozone destruction in the troposphere. Thus, a negative ∆O3 has been observed almost everywhere in the city. Aerosol composition: Two areas of maximum values of aerosol bulk concentration have been delimited in different city parts. One is a source of fine aerosol (r < 0.9 µm), the other - of the coarse one (r > 0.9 µm). Summary: 1. Apart from the obvious inflow of anthropogenic heat, an additional source of moisture has been discovered in the city. Apparently, it is automobile transport. 2. The measurements have discovered areas with significantly exceeded daily and one-time MPCs for such dangerous polluting agents as CO, NO, NO2. These are the areas with the most intensive car traffic. 3. A high level of ozone concentration has been discovered in the city's background area and the Academgorodok. 4. It is necessary to build up statistics for this type of studies and introduce this method into the air quality control methodology. As an addition to the practiced methods it will allow to achieve a more complete and correct picture of air pollution. 1. WHO. Air quality guidelines. Geneva: World Health Organization, 1999. Downloaded in February 2002 2. B. D. Belan, O. A. Pelymskii, Uzhegova N.V. (2009) Atmos. Oceanic Opt. Study of the Anthropogenic Component of Urban Heat Balance. Vol. 22, No. 4, pp. 441-445. 3. Arshinov, M.Y., B.D. Belan, D.K. Davydov, G.A. Ivlev, A.V. Kozlov, D.A. Pestunov, E.V. Pokrovskii, D.V. Simonenkov, N.V. Uzhegova, A.V. Fofonov (2005) Atmos. Oceanic Opt. AKV-2 mobile station and its use in Tomsk city as an example. No. 8, pp. 575-580

  16. Effects of a shade-matching light and background color on reliability in tooth shade selection.

    PubMed

    Najafi-Abrandabadi, Siamak; Vahidi, Farhad; Janal, Malvin N

    2018-01-01

    The purpose of this study was to evaluate the effects of a shade-matching light (Rite-Lite-2, AdDent) and different viewing backgrounds on reliability in a test of shade tab matching. Four members of the Prosthodontic faculty matched 10 shade tabs selected for a range of shades against the shade guide. All raters were tested for color blindness and were calibrated prior to the study. Matching took place under four combinations of conditions: with operatory light or the shade-matching light, and using either a pink or a blue background. Reliability was quantified with the kappa statistic, separately for agreement of value, hue, and chroma for each shade tab. In general, raters showed fair to moderate levels of agreement when judging the value of the shade tabs, but could not agree on the hue and chroma of the stimuli. The pink background led to higher levels of agreement than the blue background, and the shade-matching light improved agreement when used in conjunction with the pink but not the blue background. Moderate levels of agreement were found in matching shade tab value. Agreement was generally better when using the pink rather than the blue background, regardless of light source. The use of the shade-matching light tended to amplify the advantage of the pink background.

  17. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  18. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  19. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  20. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  1. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  2. [Applying the clustering technique for characterising maintenance outsourcing].

    PubMed

    Cruz, Antonio M; Usaquén-Perilla, Sandra P; Vanegas-Pabón, Nidia N; Lopera, Carolina

    2010-06-01

    Using clustering techniques for characterising companies providing health institutions with maintenance services. The study analysed seven pilot areas' equipment inventory (264 medical devices). Clustering techniques were applied using 26 variables. Response time (RT), operation duration (OD), availability and turnaround time (TAT) were amongst the most significant ones. Average biomedical equipment obsolescence value was 0.78. Four service provider clusters were identified: clusters 1 and 3 had better performance, lower TAT, RT and DR values (56 % of the providers coded O, L, C, B, I, S, H, F and G, had 1 to 4 day TAT values:

  3. Comparing the Value of Nonprofit Hospitals' Tax Exemption to Their Community Benefits.

    PubMed

    Herring, Bradley; Gaskin, Darrell; Zare, Hossein; Anderson, Gerard

    2018-01-01

    The tax-exempt status of nonprofit hospitals has received increased attention from policymakers interested in examining the value they provide instead of paying taxes. We use 2012 data from the Internal Revenue Service (IRS) Form 990, Centers for Medicare and Medicaid Services (CMS) Hospital Cost Reports, and American Hospital Association's (AHA) Annual Survey to compare the value of community benefits with the tax exemption. We contrast nonprofit's total community benefits to what for-profits provide and distinguish between charity and other community benefits. We find that the value of the tax exemption averages 5.9% of total expenses, while total community benefits average 7.6% of expenses, incremental nonprofit community benefits beyond those provided by for-profits average 5.7% of expenses, and incremental charity alone average 1.7% of expenses. The incremental community benefit exceeds the tax exemption for only 62% of nonprofits. Policymakers should be aware that the tax exemption is a rather blunt instrument, with many nonprofits benefiting greatly from it while providing relatively few community benefits.

  4. The Effect of Statins on Skeletal Muscle Function

    PubMed Central

    Parker, Beth A.; Capizzi, Jeffrey A.; Grimaldi, Adam S.; Clarkson, Priscilla M.; Cole, Stephanie M.; Keadle, Justin; Chipkin, Stuart; Pescatello, Linda S.; Simpson, Kathleen; White, C. Michael; Thompson, Paul D.

    2015-01-01

    Background Many clinicians believe that statins cause muscle pain, but this has not been observed in clinical trials and the effect of statins on muscle performance has not been carefully studied. Methods and Results The Effect of STatins On Skeletal Muscle Function and Performance (STOMP) study assessed symptoms and measured creatine kinase (CK), exercise capacity, and muscle strength before and after atorvastatin 80 mg or placebo were administered for 6 months to 420 healthy, statin-naive subjects. No individual CK value exceeded 10 times normal, but average CK increased 20.8 ± 141.1 U/L (p<0.0001) with atorvastatin. There were no significant changes in several measures of muscle strength or exercise capacity with atorvastatin, but more atorvastatin than placebo subjects developed myalgia (19 vs 10; p = 0.05). Myalgic subjects on atorvastatin or placebo decreased muscle strength in 5 of 14 and 4 of 14 variables respectively (p = 0.69). Conclusions These results indicate that high-dose atorvastatin for 6 months does not decrease average muscle strength or exercise performance in healthy, previously untreated subjects. Nevertheless, this blinded, controlled trial confirms the undocumented impression that statins increase muscle complaints. Atorvastatin also increased average CK suggesting that statins produce mild muscle injury even among asymptomatic subjects. This increase in CK should prompt studies examining the effects of more prolonged, high-dose statin treatment on muscular performance. Clinical Trial Registration Information: www.clinicaltrials.gov; Identifier: NCT00609063. PMID:23183941

  5. Predicting Depression From Language-Based Emotion Dynamics: Longitudinal Analysis of Facebook and Twitter Status Updates

    PubMed Central

    Kern, Margaret L; Fulcher, Ben D; Rickard, Nikki S

    2018-01-01

    Background Frequent expression of negative emotion words on social media has been linked to depression. However, metrics have relied on average values, not dynamic measures of emotional volatility. Objective The aim of this study was to report on the associations between depression severity and the variability (time-unstructured) and instability (time-structured) in emotion word expression on Facebook and Twitter across status updates. Methods Status updates and depression severity ratings of 29 Facebook users and 49 Twitter users were collected through the app MoodPrism. The average proportion of positive and negative emotion words used, within-person variability, and instability were computed. Results Negative emotion word instability was a significant predictor of greater depression severity on Facebook (rs(29)=.44, P=.02, 95% CI 0.09-0.69), even after controlling for the average proportion of negative emotion words used (partial rs(26)=.51, P=.006) and within-person variability (partial rs(26)=.49, P=.009). A different pattern emerged on Twitter where greater negative emotion word variability indicated lower depression severity (rs(49)=−.34, P=.01, 95% CI −0.58 to 0.09). Differences between Facebook and Twitter users in their emotion word patterns and psychological characteristics were also explored. Conclusions The findings suggest that negative emotion word instability may be a simple yet sensitive measure of time-structured variability, useful when screening for depression through social media, though its usefulness may depend on the social media platform. PMID:29739736

  6. Quantifying spatiotemporal variability of fine particles in an urban environment using combined fixed and mobile measurements

    NASA Astrophysics Data System (ADS)

    Sullivan, R. C.; Pryor, S. C.

    2014-06-01

    Spatiotemporal variability of fine particle concentrations in Indianapolis, Indiana is quantified using a combination of high temporal resolution measurements at four fixed sites and mobile measurements with instruments attached to bicycles during transects of the city. Average urban PM2.5 concentrations are an average of ˜3.9-5.1 μg m-3 above the regional background. The influence of atmospheric conditions on ambient PM2.5 concentrations is evident with the greatest temporal variability occurring at periods of one day and 5-10 days corresponding to diurnal and synoptic meteorological processes, and lower mean wind speeds are associated with episodes of high PM2.5 concentrations. An anthropogenic signal is also evident. Higher PM2.5 concentrations coincide with morning rush hour, the frequencies of PM2.5 variability co-occur with those for carbon monoxide, and higher extreme concentrations were observed mid-week compared to weekends. On shorter time scales (

  7. Expansion and growth of structure observables in a macroscopic gravity averaged universe

    NASA Astrophysics Data System (ADS)

    Wijenayake, Tharake; Ishak, Mustapha

    2015-03-01

    We investigate the effect of averaging inhomogeneities on expansion and large-scale structure growth observables using the exact and covariant framework of macroscopic gravity (MG). It is well known that applying the Einstein's equations and spatial averaging do not commute and lead to the averaging problem and backreaction terms. For the MG formalism applied to the Friedman-Lemaitre-Robertson-Walker (FLRW) metric, the extra term can be encapsulated as an averaging density parameter denoted ΩA . An exact isotropic cosmological solution of MG for the flat FLRW metric is already known in the literature; we derive here an anisotropic exact solution. Using the isotropic solution, we compare the expansion history to current available data of distances to supernovae, baryon acoustic oscillations, cosmic microwave background last scattering surface data, and Hubble constant measurements, and find -0.05 ≤ΩA≤0.07 (at the 95% confidence level). For the flat metric case this reduces to -0.03 ≤ΩA≤0.05 . The positive part of the intervals can be rejected if a mathematical (and physical) prior is taken into account. We also find that the inclusion of this term in the fits can shift the values of the usual cosmological parameters by a few to several percents. Next, we derive an equation for the growth rate of large-scale structure in MG that includes a term due to the averaging and assess its effect on the evolution of the growth compared to that of the Lambda cold dark matter (Λ CDM ) concordance model. We find that an ΩA term of an amplitude range of [-0.04 ,-0.02 ] lead to a relative deviation of the growth from that of the Λ CDM of up to 2%-4% at late times. Thus, the shift in the growth could be of comparable amplitude to that caused by similar changes in cosmological parameters like the dark energy density parameter or its equation of state. The effect could also be comparable in amplitude to some systematic effects considered for future surveys. This indicates that the averaging term and its possible effect need to be tightly constrained in future precision cosmological studies.

  8. Environmental radiation and potential ecological risk levels in the intertidal zone of southern region of Tamil Nadu coast (HBRAs), India.

    PubMed

    Punniyakotti, J; Ponnusamy, V

    2018-02-01

    Natural radioactivity content and heavy metal concentration in the intertidal zone sand samples from the southern region of Tamil Nadu coast, India, have been analyzed using gamma ray spectrometer and ICP-OES, respectively. From gamma spectral analysis, the average radioactivity contents of 238 U, 232 Th, and 40 K in the intertidal zone sand samples are 12.13±4.21, 59.03±4.26, and 197.03±26.24Bq/kg, respectively. The average radioactivity content of 232 Th alone is higher than the world average value. From the heavy metal analysis, the average Cd, Cr, Cu, Ni, Pb, and Zn concentrations are 3.1, 80.24, 82.84, 23.66, 91.67, and 137.07ppm, respectively. The average Cr and Ni concentrations are lower, whereas other four metal (Cd, Cu, Pb, and Zn) concentrations are higher than world surface rock average values. From pollution assessment parameter values, the pollution level is "uncontaminated to moderately contaminated" in the study area. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Monitoring diffuse degassing in monogentic volcanic field during a quiescent period: the case of Cumbre Vieja (La Palma,Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Burns, F.; Cole, M.; Vaccaro, W.; Alonso Cótchico, M.; Melián, G.; Asensio-Ramos, M.; Padron, E.; Hernandez Perez, P. A.; Perez, N. M.

    2017-12-01

    Volcanic activity at La Palma (Canary Islands) in the last 123 ka has taken place exclusively at the southern part of the island, where Cumbre Vieja volcano, which is characterized by a main north-south rift zone 20 km long and up to 1950 m in elevation and covering an area of 220 km2 with vents located also at the northwest and northeast. Cumbre Vieja is the most active basaltic volcano in the Canaries with 7 historical eruptions being San Juan (1949) and Teneguía (1971) the most recent ones. Since no visible degassing (fumaroles, etc.) at Cumbre Vieja occurs, our geochemical program for the volcanic surveillance of Cumbre Vieja is mainly focused on diffuse degassing monitoring. Diffuse CO2 emission surveys are yearly performed in summer to minimize the influence of meteorological variations. About 570 sampling sites were selected for each survey to obtain a homogeneous distribution after taking into consideration the local geology, structure, and accessibility. Measurements of soil CO2 efflux were performed in situ by means of a portable non-dispersive infrared sensor following the accumulation chamber method. The soil CO2 efflux values of the 2017 survey ranged from non-detectable to 47.7 g m-2 d-1. Statistical-graphical analysis of the data show two different geocheleemical populations; background (B) and peak (P) represented by 98.2% and 1.8% of the total data, respectively. The geometric means of the B and P populations are 2.9 and 36.5 g m-2 d-1, respectively. Most of the area showed B values while the P values were mainly observed both flanks of the main N-S volcanic rift. To estimate the diffuse CO2 emission in metric tons per day released from Cumbre Vieja (220 km2) for the 2017 survey, we ran about 100 sGs simulations. The estimated 2017 diffuse CO2 output released to atmosphere by Cumbre Vieja was at 801 ± 27 t d-1, value relatively higher than the background average of CO2 emission estimated on 374 t d-1 and within the background range of 132 t d-1 (-1σ) and 1.254 t d-1 (+1σ) observed at Cumbre Vieja volcano during the period 2001-2013 (Padrón et al., 2015. Bull. Volcanol. 77:28). Monitoring the diffuse CO2 emission contributes to detect early warning signals of volcanic unrest at Cumbre Vieja volcano.

  10. Exploring Patient Values in Medical Decision Making: A Qualitative Study

    PubMed Central

    Lee, Yew Kong; Low, Wah Yun; Ng, Chirk Jenn

    2013-01-01

    Background Patient decisions are influenced by their personal values. However, there is a lack of clarity and attention on the concept of patient values in the clinical context despite clear emphasis on patient values in evidence-based medicine and shared decision making. The aim of the study was to explore the concept of patient values in the context of making decisions about insulin initiation among people with type 2 diabetes. Methods and Findings We conducted individual in-depth interviews with people with type 2 diabetes who were making decisions about insulin treatment. Participants were selected purposively to achieve maximum variation. A semi-structured topic guide was used to guide the interviews which were audio-recorded and analysed using a thematic approach. We interviewed 21 participants between January 2011 and March 2012. The age range of participants was 28–67 years old. Our sample comprised 9 women and 12 men. Three main themes, ‘treatment-specific values’, ‘life goals and philosophies’, and ‘personal and social background’, emerged from the analysis. The patients reported a variety of insulin-specific values, which were negative and/or positive beliefs about insulin. They framed insulin according to their priorities and philosophies in life. Patients’ decisions were influenced by sociocultural (e.g. religious background) and personal backgrounds (e.g. family situations). Conclusions This study highlighted the need for expanding the current concept of patient values in medical decision making. Clinicians should address more than just values related to treatment options. Patient values should include patients’ priorities, life philosophy and their background. Current decision support tools, such as patient decision aids, should consider these new dimensions when clarifying patient values. PMID:24282518

  11. Scalar field vacuum expectation value induced by gravitational wave background

    NASA Astrophysics Data System (ADS)

    Jones, Preston; McDougall, Patrick; Ragsdale, Michael; Singleton, Douglas

    2018-06-01

    We show that a massless scalar field in a gravitational wave background can develop a non-zero vacuum expectation value. We draw comparisons to the generation of a non-zero vacuum expectation value for a scalar field in the Higgs mechanism and with the dynamical Casimir vacuum. We propose that this vacuum expectation value, generated by a gravitational wave, can be connected with particle production from gravitational waves and may have consequences for the early Universe where scalar fields are thought to play an important role.

  12. Erythropoiesis-stimulating agent dosing, haemoglobin and ferritin levels in UK haemodialysis patients 2005–13

    PubMed Central

    Caskey, Fergus; Ben-Shlomo, Yoav; Sterne, Jonathan A.C.; Gilg, Julie; Nitsch, Dorothea; Tomson, Charles

    2017-01-01

    ABSTRACT Background: Erythropoiesis-stimulating agents (ESAs) with intravenous iron supplementation are the main treatment for anaemia in patients with chronic kidney disease. Although observational studies suggest better outcomes for patients who achieve higher haemoglobin (Hb) levels, randomized controlled trials comparing higher and lower Hb targets have led to safety concerns over higher targets and to changes in treatment guidelines. Methods: Quarterly data from 2005 to 2013 were obtained on 28 936 haemodialysis patients from the UK Renal Registry. We examined trends in ESA use and average dose, Hb and ferritin values over time and Hb according to the UK Renal Association guideline range. Results: The average ESA dose declined over time, with sharper decreases of epoetin seen towards the end of 2006 and from 2009. Average Hb for patients on ESAs was 114.1 g/L [95% confidence interval (CI) 113.7, 114.6] in the first quarter of 2005, which decreased to 109.6 g/L (95% CI 109.3, 109.9) by the end of 2013. Average serum ferritin was 353 µg/L (95% CI 345, 360) at the start of 2005, increasing to 386 µg/L (95% CI 380, 392) in the final quarter of 2013. The percentage of patients with Hb in the range of 100–120 g/L increased from 46.1 at the start of 2005 to 57.6 at the end of 2013. Conclusions: Anaemia management patterns for haemodialysis patients changed in the UK between 2005 and 2013. These patterns most likely reflect clinician response to emerging trial evidence and practice guidelines. Registries play an important role in continued observation of anaemia management and will monitor further changes as new evidence on optimal care emerges. PMID:27190350

  13. Representation of regional urban development conditions using a watershed-based gradient study design

    USGS Publications Warehouse

    Terziotti, Silvia; McMahon, Gerard; Bell, Amanda H.

    2012-01-01

    As part of the U.S. Geological Survey National Water-Quality Assessment Program, the effects of urbanization on stream ecosystems (EUSE) have been intensively investigated in nine metropolitan areas in the United States, including Boston, Massachusetts; Atlanta, Georgia; Birmingham, Alabama; Raleigh, North Carolina; Salt Lake City, Utah; Denver, Colorado; Dallas–Fort Worth, Texas; Portland, Oregon; and Milwaukee–Green Bay, Wisconsin. Each of the EUSE study area watersheds was associated with one ecological region of the United States. This report evaluates whether each metropolitan area can be generalized across the ecological regions (ecoregions) within which the EUSE study watersheds are located. Seven characteristics of the EUSE watersheds that affect stream ecosystems were examined to determine the similarities in the same seven characteristics of the watersheds in the entire ecoregion. Land cover (percentage developed, forest and shrubland, and herbaceous and cultivated classes), average annual temperature, average annual precipitation, average surface elevation, and average percentage slope were selected as human-influenced, climate, and topography characteristics. Three findings emerged from this comparison that have implications for the use of EUSE data in models used to predict stream ecosystem condition. One is that the predominant or "background" land-cover type (either forested or agricultural land) in each ecoregion also is the predominant land-cover type within the associated EUSE study watersheds. The second finding is that in all EUSE study areas, the watersheds account for the range of developed land conditions that exist in the corresponding ecoregion watersheds. However, six of the nine EUSE study area watersheds have significantly different distributions of developed land from the ecoregion watersheds. Finally, in seven of the nine EUSE/ecoregion comparisons, the distributions of the values of climate variables in the EUSE watersheds are different from the distributions for watersheds in the corresponding ecoregions.

  14. Search for the Tunguska event in the Antarctic snow

    NASA Technical Reports Server (NTRS)

    Rocchia, R.; Deangelis, M.; Doclet, D.; Bonte, PH.; Jehanno, C.; Robin, E.

    1988-01-01

    The Tunguska explosion in 1908 is supposed to have been produced by the impact of a small celestial body. The absence of any identifiable crater together with the huge energy released by the event suggest that the impactor exploded in midair and that its material was widely spread over the Earth. The short term contribution of such exceptional events to the total accretion rate of extraterrestrial material by the Earth could be significant. Samples were chosen in a core electromechanically drilled in 1984 near South Pole Station. There, the low temperatures, preventing melting all year long, and the nearly regular snow fall rate provide good conditions for a reliable continuous record of any infalling material. In many samples Ir was below the detection limit of the instrumentation. The iridium infall averaged over 45 samples is given. In a few samples the iridium content is significantly higher than the average: the frequency and amplitude of such fluctuations can be explained by the presence on some filters of finite size cosmic particles. No significant systematic increase above the average level is observed in the part of the core corresponding to the Tunguska event. The two major results of this study are: (1) The presence of Tunguska explosion debris in the Antarctic snow is not confirmed; and (2) The estimate of the average iridium infall, is an order of magnitude lower than the Ganapathy's background but is close to the values measured in Antarctic snow and atmospheric samples by Takahashi et al. The results are also consistent with the flux of micrometeoroids deduced from optical and radar observations or derived from the study of Greenland cosmic dust collection but are lower than the flux at mid-latitude measured in paleocene-oligocene sediments from the central part of the Pacific Ocean.

  15. Healthcare utilization and cost of Stevens-Johnson syndrome and toxic epidermal necrolysis management in Thailand

    PubMed Central

    Dilokthornsakul, P; Sawangjit, R; Inprasong, C; Chunhasewee, S; Rattanapan, P; Thoopputra, T; Chaiyakunapruk, N

    2016-01-01

    Background: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are life-threatening dermatologic conditions. Although, the incidence of SJS/TEN in Thailand is high, information on cost of care for SJS/TEN is limited. This study aims to estimate healthcare resource utilization and cost of SJS/TEN in Thailand, using hospital perspective. Methods: A retrospective study using an electronic health database from a university-affiliated hospital in Thailand was undertaken. Patients admitted with SJS/TEN from 2002 to 2007 were included. Direct medical cost was estimated by the cost-to-charge ratio. Cost was converted to 2013 value by consumer price index, and converted to $US using 31 Baht/1 $US. The healthcare resource utilization was also estimated. Results: A total of 157 patients were included with average age of 45.3±23.0 years. About 146 patients (93.0%) were diagnosed as SJS and the remaining (7.0%) were diagnosed as TEN. Most of the patients (83.4%) were treated with systemic corticosteroids. Overall, mortality rate was 8.3%, while the average length of stay (LOS) was 10.1±13.2 days. The average cost of managing SJS/TEN for all patients was $1,064±$2,558. The average cost for SJS patients was $1,019±$2,601 while that for TEN patients was $1,660±$1,887. Conclusions: Healthcare resource utilization and cost of care for SJS/TEN in Thailand were tremendous. The findings are important for policy makers to allocate healthcare resources and develop strategies to prevent SJS/TEN which could decrease length of stay and cost of care. PMID:27089110

  16. Trends of atmospheric black carbon concentration over the United Kingdom

    NASA Astrophysics Data System (ADS)

    Singh, Vikas; Ravindra, Khaiwal; Sahu, Lokesh; Sokhi, Ranjeet

    2018-04-01

    The continuous observations over a period of 7 years (2009-2016) available at 7 locations show declining trend of atmospheric BC in the UK. Among all the locations, the highest decrease of 8 ± 3 percent per year was observed at the Marylebone road in London. The detailed analysis performed at 21 locations during 2009-2011 shows that average annual mean atmospheric BC concentration were 0.45 ± 0.10, 1.47 ± 0.58, 1.34 ± 0.31, 1.83 ± 0.46 and 9.72 ± 0.78 μgm-3 at rural, suburban, urban background, urban centre and kerbside sites respectively. Around 1 μgm-3 of atmospheric BC could be attributed to urban emission, whereas traffic contributed up to 8 μg m-3 of atmospheric BC near busy roads. Seasonal pattern was also observed at all locations except rural and kerbside location, with maximum concentrations (1.2-4 μgm-3) in winter. Further, minimum concentrations (0.3-1.2 μgm-3) were observed in summer and similar concentrations in spring and fall. At suburban and urban background locations, similar diurnal pattern were observed with atmospheric BC concentration peaks (≈1.8 μg m-3) in the morning (around 9 a.m.) and evening (7-9 p.m.) rush hours, whereas minimum concentrations were during late night hours (peak at 5 a.m.) and the afternoon hours (peak at 2 p.m.). The urban centre values show a similar morning pattern (peak at 9 a.m.; concentration - 2.5 μgm-3) in relation to background locations but only a slight decrease in concentration in the afternoon which remained above 2 μgm-3 till midnight. It is concluded that the higher flow of traffic at urban centre locations results in higher atmospheric BC concentrations throughout the day. Comparison of weekday and weekend daily averaged atmospheric BC showed maximum concentrations on Friday, having minimum levels on Sunday. This study will help to refine the atmospheric BC emission inventories and provide data for air pollution and climate change models evaluation, which are used to formulate air pollution mitigation policies.

  17. Potential Release Site Sediment Concentrations Correlated to Storm Water Station Runoff through GIS Modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    C.T. McLean

    2005-06-01

    This research examined the relationship between sediment sample data taken at Potential Release Sites (PRSs) and storm water samples taken at selected sites in and around Los Alamos National Laboratory (LANL). The PRSs had been evaluated for erosion potential and a matrix scoring system implemented. It was assumed that there would be a stronger relationship between the high erosion PRSs and the storm water samples. To establish the relationship, the research was broken into two areas. The first area was raster-based modeling, and the second area was data analysis utilizing the raster based modeling results and the sediment and stormmore » water sample results. Two geodatabases were created utilizing raster modeling functions and the Arc Hydro program. The geodatabase created using only Arc Hydro functions contains very fine catchment drainage areas in association with the geometric network and can be used for future contaminant tracking. The second geodatabase contains sub-watersheds for all storm water stations used in the study along with a geometric network. The second area of the study focused on data analysis. The analytical sediment data table was joined to the PRSs spatial data in ArcMap. All PRSs and PRSs with high erosion potential were joined separately to create two datasets for each of 14 analytes. Only the PRSs above the background value were retained. The storm water station spatial data were joined to the table of analyte values that were either greater than the National Pollutant Discharge Elimination System (NPDES) Multi-Sector General Permit (MSGP) benchmark value, or the Department of Energy (DOE) Drinking Water Defined Contribution Guideline (DWDCG). Only the storm water stations were retained that had sample values greater than the NPDES MSGP benchmark value or the DOE DWDCG. Separate maps were created for each analyte showing the sub-watersheds, the PRSs over background, and the storm water stations greater than the NPDES MSGP benchmark value or the DOE DWDCG. Tables were then created for each analyte that listed the PRSs average value by storm water station allowing a tabular view of the mapped data. The final table that was created listed the number of high erosion PRSs and regular PRSs over background values that were contained in each watershed. An overall relationship between the high erosion PRSs or the regular PRSs and the storm water stations was not identified through the methods used in this research. However, the Arc Hydro data models created for this analysis were used to track possible sources of contamination found through sampling at the storm water gaging stations. This geometric network tracing was used to identify possible relationships between the storm water stations and the PRSs. The methods outlined for the geometric network tracing could be used to find other relationships between the sites. A cursory statistical analysis was performed which could be expanded and applied to the data sets generated during this research to establish a broader relationship between the PRSs and storm water stations.« less

  18. Aged Riverine Particulate Organic Carbon in Four UK Catchments

    NASA Astrophysics Data System (ADS)

    Adams, Jessica; Tipping, Edward; Bryant, Charlotte; Helliwell, Rachel; Toberman, Hannah; Quinton, John

    2016-04-01

    The riverine transport of particulate organic matter (POM) is a significant flux in the carbon cycle, and affects macronutrients and contaminants. We used radiocarbon to characterise POM at 9 riverine sites of four UK catchments (Avon, Conwy, Dee, Ribble) over a one-year period. High-discharge samples were collected on three or four occasions at each site. Suspended particulate matter (SPM) was obtained by centrifugation, and the samples were analysed for carbon isotopes. Concentrations of SPM and SPM organic carbon (OC) contents were also determined, and were found to have a significant negative correlation. For the 7 rivers draining predominantly rural catchments, PO14C values, expressed as percent modern carbon absolute (pMC), varied little among samplings at each site, and there was no significant difference in the average values among the sites. The overall average PO14C value for the 7 sites of 91.2 pMC corresponded to an average age of 680 14C years, but this value arises from the mixing of differently-aged components, and therefore significant amounts of organic matter older than the average value are present in the samples. Although topsoil erosion is probably the major source of the riverine POM, the average PO14C value is appreciably lower than topsoil values (which are typically 100 pMC). This is most likely explained by inputs of older subsoil OC from bank erosion, or the preferential loss of high-14C topsoil organic matter by mineralisation during riverine transport. The significantly lower average PO14C of samples from the River Calder (76.6 pMC), can be ascribed to components containing little or no radiocarbon, derived either from industrial sources or historical coal mining, and this effect is also seen in the River Ribble, downstream of its confluence with the Calder. At the global scale, the results significantly expand available information for PO14C in rivers draining catchments with low erosion rates.

  19. The Pedestrian Detection Method Using an Extension Background Subtraction about the Driving Safety Support Systems

    NASA Astrophysics Data System (ADS)

    Muranaka, Noriaki; Date, Kei; Tokumaru, Masataka; Imanishi, Shigeru

    In recent years, the traffic accident occurs frequently with explosion of traffic density. Therefore, we think that the safe and comfortable transportation system to defend the pedestrian who is the traffic weak is necessary. First, we detect and recognize the pedestrian (the crossing person) by the image processing. Next, we inform all the drivers of the right or left turn that the pedestrian exists by the sound and the image and so on. By prompting a driver to do safe driving in this way, the accident to the pedestrian can decrease. In this paper, we are using a background subtraction method for the movement detection of the movement object. In the background subtraction method, the update method in the background was important, and as for the conventional way, the threshold values of the subtraction processing and background update were identical. That is, the mixing rate of the input image and the background image of the background update was a fixation value, and the fine tuning which corresponded to the environment change of the weather was difficult. Therefore, we propose the update method of the background image that the estimated mistake is difficult to be amplified. We experiment and examines in the comparison about five cases of sunshine, cloudy, evening, rain, sunlight change, except night. This technique can set separately the threshold values of the subtraction processing and background update processing which suited the environmental condition of the weather and so on. Therefore, the fine tuning becomes possible freely in the mixing rate of the input image and the background image of the background update. Because the setting of the parameter which suited an environmental condition becomes important to minimize mistaking percentage, we examine about the setting of a parameter.

  20. Retrievals of Thick Cloud Optical Depth from the Geoscience Laser Altimeter System (GLAS) by Calibration of Solar Background Signal

    NASA Technical Reports Server (NTRS)

    Yang, Yuekui; Marshak, Alexander; Chiu, J. Christine; Wiscombe, Warren J.; Palm, Stephen P.; Davis, Anthony B.; Spangenberg, Douglas A.; Nguyen, Louis; Spinhirne, James D.; Minnis, Patrick

    2008-01-01

    Laser beams emitted from the Geoscience Laser Altimeter System (GLAS), as well as other space-borne laser instruments, can only penetrate clouds to a limit of a few optical depths. As a result, only optical depths of thinner clouds (< about 3 for GLAS) are retrieved from the reflected lidar signal. This paper presents a comprehensive study of possible retrievals of optical depth of thick clouds using solar background light and treating GLAS as a solar radiometer. To do so we first calibrate the reflected solar radiation received by the photon-counting detectors of GLAS' 532 nm channel, which is the primary channel for atmospheric products. The solar background radiation is regarded as a noise to be subtracted in the retrieval process of the lidar products. However, once calibrated, it becomes a signal that can be used in studying the properties of optically thick clouds. In this paper, three calibration methods are presented: (I) calibration with coincident airborne and GLAS observations; (2) calibration with coincident Geostationary Operational Environmental Satellite (GOES) and GLAS observations of deep convective clouds; (3) calibration from the first principles using optical depth of thin water clouds over ocean retrieved by GLAS active remote sensing. Results from the three methods agree well with each other. Cloud optical depth (COD) is retrieved from the calibrated solar background signal using a one-channel retrieval. Comparison with COD retrieved from GOES during GLAS overpasses shows that the average difference between the two retrievals is 24%. As an example, the COD values retrieved from GLAS solar background are illustrated for a marine stratocumulus cloud field that is too thick to be penetrated by the GLAS laser. Based on this study, optical depths for thick clouds will be provided as a supplementary product to the existing operational GLAS cloud products in future GLAS data releases.

  1. New method for quantification of vuggy porosity from digital optical borehole images as applied to the karstic Pleistocene limestone of the Biscayne aquifer, southeastern Florida

    USGS Publications Warehouse

    Cunningham, K.J.; Carlson, J.I.; Hurley, N.F.

    2004-01-01

    Vuggy porosity is gas- or fluid-filled openings in rock matrix that are large enough to be seen with the unaided eye. Well-connected vugs can form major conduits for flow of ground water, especially in carbonate rocks. This paper presents a new method for quantification of vuggy porosity calculated from digital borehole images collected from 47 test coreholes that penetrate the karstic Pleistocene limestone of the Biscayne aquifer, southeastern Florida. Basically, the method interprets vugs and background based on the grayscale color of each in digital borehole images and calculates a percentage of vuggy porosity. Development of the method was complicated because environmental conditions created an uneven grayscale contrast in the borehole images that makes it difficult to distinguish vugs from background. The irregular contrast was produced by unbalanced illumination of the borehole wall, which was a result of eccentering of the borehole-image logging tool. Experimentation showed that a simple, single grayscale threshold would not realistically differentiate between the grayscale contrast of vugs and background. Therefore, an equation was developed for an effective subtraction of the changing grayscale contrast, due to uneven illumination, to produce a grayscale threshold that successfully identifies vugs. In the equation, a moving average calculated around the circumference of the borehole and expressed as the background grayscale intensity is defined as a baseline from which to identify a grayscale threshold for vugs. A constant was derived empirically by calibration with vuggy porosity values derived from digital images of slabbed-core samples and used to make the subtraction from the background baseline to derive the vug grayscale threshold as a function of azimuth. The method should be effective in estimating vuggy porosity in any carbonate aquifer. ?? 2003 Published by Elsevier B.V.

  2. Lutetium oxyorthosilicate (LSO) intrinsic activity correction and minimal detectable target activity study for SPECT imaging with a LSO-based animal PET scanner

    NASA Astrophysics Data System (ADS)

    Yao, Rutao; Ma, Tianyu; Shao, Yiping

    2008-08-01

    This work is part of a feasibility study to develop SPECT imaging capability on a lutetium oxyorthosilicate (LSO) based animal PET system. The SPECT acquisition was enabled by inserting a collimator assembly inside the detector ring and acquiring data in singles mode. The same LSO detectors were used for both PET and SPECT imaging. The intrinsic radioactivity of 176Lu in the LSO crystals, however, contaminates the SPECT data, and can generate image artifacts and introduce quantification error. The objectives of this study were to evaluate the effectiveness of a LSO background subtraction method, and to estimate the minimal detectable target activity (MDTA) of image object for SPECT imaging. For LSO background correction, the LSO contribution in an image study was estimated based on a pre-measured long LSO background scan and subtracted prior to the image reconstruction. The MDTA was estimated in two ways. The empirical MDTA (eMDTA) was estimated from screening the tomographic images at different activity levels. The calculated MDTA (cMDTA) was estimated from using a formula based on applying a modified Currie equation on an average projection dataset. Two simulated and two experimental phantoms with different object activity distributions and levels were used in this study. The results showed that LSO background adds concentric ring artifacts to the reconstructed image, and the simple subtraction method can effectively remove these artifacts—the effect of the correction was more visible when the object activity level was near or above the eMDTA. For the four phantoms studied, the cMDTA was consistently about five times of the corresponding eMDTA. In summary, we implemented a simple LSO background subtraction method and demonstrated its effectiveness. The projection-based calculation formula yielded MDTA results that closely correlate with that obtained empirically and may have predicative value for imaging applications.

  3. AN ASSESSMENT OF CULTURAL VALUES AND RESIDENT-CENTERED CULTURE CHANGE IN US NURSING FACILITIES

    PubMed Central

    Banaszak-Holl, Jane; Castle, Nicholas G.; Lin, Michael; Spreitzer, Gretchen

    2012-01-01

    Background Culture Change initiatives propose to improve care by addressing the lack of managerial supports and prevalent stressful work environments in the industry; however, little is known about how Culture Change facilities differ from facilities in the industry that have not chosen to affiliate with the resident-centered care movements. Purpose To evaluate representation of organizational culture values within a random sample of U.S. nursing home facilities using the Competing Values Framework (CVF) and to determine whether organizational values are related to membership in resident-centered Culture Change initiatives. Design and Methods We collected reports of cultural values using a well-established CVF instrument in a random survey of facility administrators and directors of nursing within all states. We received responses from 57% of the facilities that were mailed the survey. Directors of nursing and administrators did not vary significantly in their reports of culture and facility measures combine their responses. Findings Nursing facilities favored market-focused cultural values on average and developmental values, key to innovation, were the least common across all nursing homes. Approximately 17% of facilities reported all cultural values were strong within their facilities. Only high developmental cultural values were linked to participation in culture change initiatives. Culture Change facilities were not different from non-Culture Change facilities in the promotion of employee focus as organizational culture, as is emphasized in group culture values. Likewise, Culture Change facilities were also not any more likely to have hierarchical or market foci than non-Culture Change facilities. Practice Implications Our results counter the argument that Culture Change facilities have a stronger internal employee focus than facilities more generally but does show that Culture Change facilities report stronger developmental cultures than non-Culture Change facilities, which indicates a potential to be innovative in their strategies. Facilities are culturally ready to become resident-centered and may face other barriers to adopting these practices. PMID:22936002

  4. Environmental background values of trace elements in sediments from the Jiaozhou Bay catchment, Qingdao, China.

    PubMed

    Xu, Fangjian; Liu, Zhaoqing; Yuan, Shengqiang; Zhang, Xilin; Sun, Zhilei; Xu, Feng; Jiang, Zuzhou; Li, Anchun; Yin, Xuebo

    2017-08-15

    Selected trace elements (As, Cr, Zn, Cu, Cd, Co, Pb and Ni) in 76 surface sediment samples collected from the rivers and the intertidal zone of Jiaozhou Bay (JZB) were evaluated to assess their environmental background values in the JZB catchment. Overall, the sediment quality in the area meets the China Marine Sediment Quality criteria. The background values (ranges) of the elements As, Cr, Zn, Cu, Cd, Co, Pb and Ni were, respectively, 8.28 (4.10-12.46), 67.96 (38.40-97.52), 56.80 (16.42-196.51), 19.13 (5.71-64.06), 0.10 (0.02-0.42), 6.51 (2.08-20.40), 17.97 (12.26-55.84) and 20.69 (10.43-30.95)mg/kg. The background values of most of the trace elements were lower than those in Chinese soil, the upper continental crust, global shales and global preindustrial sediments. The results may assist in defining future coastal and river management measures specifically targeted at monitoring trace element contamination in the JZB catchment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. 17 CFR 275.205-2 - Definition of “specified period” over which the asset value of the company or fund under...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... periodâ over which the asset value of the company or fund under management is averaged. 275.205-2 Section... REGULATIONS, INVESTMENT ADVISERS ACT OF 1940 § 275.205-2 Definition of “specified period” over which the asset value of the company or fund under management is averaged. (a) For purposes of this rule: (1) Fulcrum...

  6. Hand-held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength

    PubMed Central

    Knols, Ruud H; Aufdemkampe, Geert; de Bruin, Eling D; Uebelhart, Daniel; Aaronson, Neil K

    2009-01-01

    Background Hand-held dynamometry is a portable and inexpensive method to quantify muscle strength. To determine if muscle strength has changed, an examiner must know what part of the difference between a patient's pre-treatment and post-treatment measurements is attributable to real change, and what part is due to measurement error. This study aimed to determine the relative and absolute reliability of intra and inter-observer strength measurements with a hand-held dynamometer (HHD). Methods Two observers performed maximum voluntary peak torque measurements (MVPT) for isometric knee extension in 24 patients with haematological malignancies. For each patient, the measurements were carried out on the same day. The main outcome measures were the intraclass correlation coefficient (ICC ± 95%CI), the standard error of measurement (SEM), the smallest detectable difference (SDD), the relative values as % of the grand mean of the SEM and SDD, and the limits of agreement for the intra- and inter-observer '3 repetition average' and the 'highest value of 3 MVPT' knee extension strength measures. Results The intra-observer ICCs were 0.94 for the average of 3 MVPT (95%CI: 0.86–0.97) and 0.86 for the highest value of 3 MVPT (95%CI: 0.71–0.94). The ICCs for the inter-observer measurements were 0.89 for the average of 3 MVPT (95%CI: 0.75–0.95) and 0.77 for the highest value of 3 MVPT (95%CI: 0.54–0.90). The SEMs for the intra-observer measurements were 6.22 Nm (3.98% of the grand mean (GM) and 9.83 Nm (5.88% of GM). For the inter-observer measurements, the SEMs were 9.65 Nm (6.65% of GM) and 11.41 Nm (6.73% of GM). The SDDs for the generated parameters varied from 17.23 Nm (11.04% of GM) to 27.26 Nm (17.09% of GM) for intra-observer measurements, and 26.76 Nm (16.77% of GM) to 31.62 Nm (18.66% of GM) for inter-observer measurements, with similar results for the limits of agreement. Conclusion The results indicate that there is acceptable relative reliability for evaluating knee strength with a HHD, while the measurement error observed was modest. The HHD may be useful in detecting changes in knee extension strength at the individual patient level. PMID:19272149

  7. Ensemble-Based Parameter Estimation in a Coupled GCM Using the Adaptive Spatial Average Method

    DOE PAGES

    Liu, Y.; Liu, Z.; Zhang, S.; ...

    2014-05-29

    Ensemble-based parameter estimation for a climate model is emerging as an important topic in climate research. And for a complex system such as a coupled ocean–atmosphere general circulation model, the sensitivity and response of a model variable to a model parameter could vary spatially and temporally. An adaptive spatial average (ASA) algorithm is proposed to increase the efficiency of parameter estimation. Refined from a previous spatial average method, the ASA uses the ensemble spread as the criterion for selecting “good” values from the spatially varying posterior estimated parameter values; these good values are then averaged to give the final globalmore » uniform posterior parameter. In comparison with existing methods, the ASA parameter estimation has a superior performance: faster convergence and enhanced signal-to-noise ratio.« less

  8. Human perceptions of colour rendition vary with average fidelity, average gamut, and gamut shape

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Royer, MP; Wilkerson, A.; Wei, M.

    An experiment was conducted to evaluate how subjective impressions of color quality vary with changes in average fidelity, average gamut, and gamut shape (which considers the specific hues that are saturated or desaturated). Twenty-eight participants each evaluated 26 lighting conditions—created using four, seven-channel, tunable LED luminaires—in a 3.1 m by 3.7 m room filled with objects selected to cover a range of hue, saturation, and lightness. IES TM-30 fidelity index (Rf) values ranged from 64 to 93, IES TM-30 gamut index (Rg¬) values from 79 to 117, and IES TM-30 Rcs,h1 values (a proxy for gamut shape) from -19% tomore » 26%. All lighting conditions delivered the same nominal illuminance and chromaticity. Participants were asked to rate each condition on eight point semantic differential scales for saturated-dull, normal-shifted, and like-dislike. They were also asked one multiple choice question, classifying the condition as saturated, dull, normal, or shifted. The findings suggest that gamut shape is more important than average gamut for human preference, where reds play a more important role than other hues. Additionally, average fidelity alone is a poor predictor of human perceptions, although Rf was somewhat better than CIE Ra. The most preferred source had a CIE Ra value of 68, and 9 of the top 12 rated products had a CIE Ra value of 73 or less, which indicates that the commonly used criteria of CIE Ra ≥ 80 may be excluding a majority of preferred light sources.« less

  9. [Low caloric value and high salt content in the meals served in school canteens].

    PubMed

    Paiva, Isabel; Pinto, Carlos; Queirós, Laurinda; Meister, Maria Cristina; Saraiva, Margarida; Bruno, Paula; Antunes, Delfina; Afonso, Manuel

    2011-01-01

    School lunch can contribute to aggravate food quality, by excess or deficiency, or it can contribute to compensate and alleviate them. This school meal should be an answer to combating the epidemic of obesity, and to feed some grace children. The objective was to study the nutritional composition of catering in canteens of public schools, from Northern municipalities in the District of Porto: Vila do Conde, Póvoa de Varzim, Santo Tirso and Trofa. Meals were subjected to laboratory analysis. Thirty two meals, four per each school were analysed, reference values for the analysis of the nutritional composition of meals were dietary reference intakes (USA) and eating well at school (UK). The average energy meal content was 447 kcal and the median 440 kcal (22% of daily calories). The average values of nutrients, per meal, were: lipids 9, 8 g, carbohydrate 65,7 g and proteins 24,0 g. In average the contribution for the meal energy was: 20% fat, 59% carbohydrate and 21% protein. In more than 75% of meals the contribution of lipid content was below the lower bound of the reference range. The average content of sodium chloride per meal was 3.4 g, and the confidence interval 95% to average 3.0 to 3.8 g, well above the recommended maximum value of 1.5 grams. The average content fiber per meal was 10.8 g higher than the minimum considered appropriate. In conclusion, the value low caloric meals was mainly due to the low fat content, and content salt of any of the components of the meal was very high.

  10. Estimating Exceptionally Rare Germline and Somatic Mutation Frequencies via Next Generation Sequencing

    PubMed Central

    Yoon, Song-Ro; Arnheim, Norman; Calabrese, Peter

    2016-01-01

    We used targeted next generation deep-sequencing (Safe Sequencing System) to measure ultra-rare de novo mutation frequencies in the human male germline by attaching a unique identifier code to each target DNA molecule. Segments from three different human genes (FGFR3, MECP2 and PTPN11) were studied. Regardless of the gene segment, the particular testis donor or the 73 different testis pieces used, the frequencies for any one of the six different mutation types were consistent. Averaging over the C>T/G>A and G>T/C>A mutation types the background mutation frequency was 2.6x10-5 per base pair, while for the four other mutation types the average background frequency was lower at 1.5x10-6 per base pair. These rates far exceed the well documented human genome average frequency per base pair (~10−8) suggesting a non-biological explanation for our data. By computational modeling and a new experimental procedure to distinguish between pre-mutagenic lesion base mismatches and a fully mutated base pair in the original DNA molecule, we argue that most of the base-dependent variation in background frequency is due to a mixture of deamination and oxidation during the first two PCR cycles. Finally, we looked at a previously studied disease mutation in the PTPN11 gene and could easily distinguish true mutations from the SSS background. We also discuss the limits and possibilities of this and other methods to measure exceptionally rare mutation frequencies, and we present calculations for other scientists seeking to design their own such experiments. PMID:27341568

  11. Mercury contamination in bank swallows and double-crested cormorants from the Carson River, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, R.; Brewer, R.; Peterson, S.C.

    1995-12-31

    An ecological risk assessment was performed in conjunction with a remedial investigation at the Carson River Mercury Site (CRMS) in northwestern Nevada. Large quantities of mercury used in the processing of gold and silver during mining operations in the mid to late 1800s are distributed throughout the Carson River ecosystem. Previous investigations indicated elevated levels of mercury in soil, sediment, water, and the aquatic food chain. Bird exposure to mercury was determined by measuring total mercury and monomethyl mercury in blood and feather samples from 15 unfledged double-crested cormorants (Phalacrocorax auritus), and in blood, feather, and liver samples from 18more » juvenile bank swallows (Riparia riparia) at both the CRMS and uncontaminated background locations. Monomethyl mercury accounted for 90 to 98% of the total mercury in the samples. Total mercury concentrations in bird tissues collected at the CRMS were significantly higher than at background locations. Average total mercury concentrations (wet weight) for the swallow blood, liver, and feather samples collected at the CRMS were 2.63, 3.96, and 2.01 mg/kg, respectively; compared with 0.74, 1,03, and 1.84 mg/kg, respectively at the background area. Average total mercury concentrations for cormorant samples collected at the CRMS were 17.07 mg/kg for blood, and 105.1 1 mg/kg for feathers. Cormorant samples collected at the background location had average total mercury concentrations of 0.49 mg/kg for blood and 8.99 mg/kg for feathers. Results are compared with published residue-effects levels to evaluate avian risks.« less

  12. Prognosis estimation under the light of metabolic tumor parameters on initial FDG-PET/CT in patients with primary extranodal lymphoma

    PubMed Central

    Okuyucu, Kursat; Ozaydın, Sukru; Alagoz, Engin; Ozgur, Gokhan; Oysul, Fahrettin Guven; Ozmen, Ozlem; Tuncel, Murat; Ozturk, Mustafa; Arslan, Nuri

    2016-01-01

    Abstract Background Non-Hodgkin’s lymphomas arising from the tissues other than primary lymphatic organs are named primary extranodal lymphoma. Most of the studies evaluated metabolic tumor parameters in different organs and histopathologic variants of this disease generally for treatment response. We aimed to evaluate the prognostic value of metabolic tumor parameters derived from initial FDG-PET/CT in patients with a medley of primary extranodal lymphoma in this study. Patients and methods There were 67 patients with primary extranodal lymphoma for whom FDG-PET/CT was requested for primary staging. Quantitative PET/CT parameters: maximum standardized uptake value (SUVmax), average standardized uptake value (SUVmean), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were used to estimate disease-free survival and overall survival. Results SUVmean, MTV and TLG were found statistically significant after multivariate analysis. SUVmean remained significant after ROC curve analysis. Sensitivity and specificity were calculated as 88% and 64%, respectively, when the cut-off value of SUVmean was chosen as 5.15. After the investigation of primary presentation sites and histo-pathological variants according to recurrence, there is no difference amongst the variants. Primary site of extranodal lymphomas however, is statistically important (p = 0.014). Testis and central nervous system lymphomas have higher recurrence rate (62.5%, 73%, respectively). Conclusions High SUVmean, MTV and TLG values obtained from primary staging FDG-PET/CT are potential risk factors for both disease-free survival and overall survival in primary extranodal lymphoma. SUVmean is the most significant one amongst them for estimating recurrence/metastasis. PMID:27904443

  13. Nutritive value of selected variety breads and pastas.

    PubMed

    Ranhotra, G S; Gelroth, J A; Novak, F A; Bock, M A; Winterringer, G L; Matthews, R H

    1984-03-01

    Nine types of commercially produced variety breads, plain bagels, corn tortillas, and three types of pasta products were obtained from each of four cities, New York, San Francisco, Atlanta, and Kansas City. Proximate components and 12 minerals and vitamins were determined in these and in cooked pasta products. Available carbohydrate and energy values were calculated. On the average, French, Italian, and pita breads were lower in moisture than other breads. Protein in bread products averaged between 7.6% and 10.4% and in cooked pastas and tortillas between 4.4% and 5.3%. Bagels averaged 10.2% protein. Insoluble dietary fiber in whole wheat bread averaged 5.6%; for most products, dietary fiber values were five- to eightfold higher than crude fiber values. Pasta products and tortillas were virtually free of sodium. Sodium in bread products averaged between 379 and 689 mg/100 gm. Although all pasta products and most bread products were enriched, calcium was often not included. Iron averaged from 2.16 to 3.29 mg/100 gm in bread products and 3.10 to 4.24 mg/100 gm in dry pasta products. Products made with unrefined or less-refined flours and/or containing germ and bran tended to be high in phosphorus, magnesium, zinc, and manganese, and, to a lesser extent, in copper. A good portion of potassium, thiamin, riboflavin, and niacin in pasta products was lost during cooking.

  14. Is Mathematics Education in England Working for Everyone? NFER Analysis of the PISA Performance of Disadvantaged Pupils

    ERIC Educational Resources Information Center

    Wheater, Rebecca; Durbin, Ben; McNamara, Stephen; Classick, Rachel

    2016-01-01

    The impact of socio-economic background on mathematics performance in England can be seen from the most to least disadvantaged. As socio-economic background of pupils increases, so does average mathematics performance; the gap between the most and least disadvantaged is equivalent to over three years' of schooling. However, many factors other than…

  15. Cortical processing of dynamic sound envelope transitions.

    PubMed

    Zhou, Yi; Wang, Xiaoqin

    2010-12-08

    Slow envelope fluctuations in the range of 2-20 Hz provide important segmental cues for processing communication sounds. For a successful segmentation, a neural processor must capture envelope features associated with the rise and fall of signal energy, a process that is often challenged by the interference of background noise. This study investigated the neural representations of slowly varying envelopes in quiet and in background noise in the primary auditory cortex (A1) of awake marmoset monkeys. We characterized envelope features based on the local average and rate of change of sound level in envelope waveforms and identified envelope features to which neurons were selective by reverse correlation. Our results showed that envelope feature selectivity of A1 neurons was correlated with the degree of nonmonotonicity in their static rate-level functions. Nonmonotonic neurons exhibited greater feature selectivity than monotonic neurons in quiet and in background noise. The diverse envelope feature selectivity decreased spike-timing correlation among A1 neurons in response to the same envelope waveforms. As a result, the variability, but not the average, of the ensemble responses of A1 neurons represented more faithfully the dynamic transitions in low-frequency sound envelopes both in quiet and in background noise.

  16. Inconsistency of residents' communication performance in challenging consultations.

    PubMed

    Wouda, Jan C; van de Wiel, Harry B M

    2013-12-01

    Communication performance inconsistency between consultations is usually regarded as a measurement error that jeopardizes the reliability of assessments. However, inconsistency is an important phenomenon, since it indicates that physicians' communication may be below standard in some consultations. Fifty residents performed two challenging consultations. Residents' communication competency was assessed with the CELI instrument. Residents' background in communication skills training (CST) was also established. We used multilevel analysis to explore communication performance inconsistency between the two consultations. We also established the relationships between inconsistency and average performance quality, the type of consultation, and CST background. Inconsistency accounted for 45.5% of variance in residents' communication performance. Inconsistency was dependent on the type of consultation. The effect of CST background training on performance quality was case specific. Inconsistency and average performance quality were related for those consultation combinations dissimilar in goals, structure, and required skills. CST background had no effect on inconsistency. Physician communication performance should be of high quality, but also consistent regardless of the type and complexity of the consultation. In order to improve performance quality and reduce performance inconsistency, communication education should offer ample opportunities to practice a wide variety of challenging consultations. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  17. Average is Over

    NASA Astrophysics Data System (ADS)

    Eliazar, Iddo

    2018-02-01

    The popular perception of statistical distributions is depicted by the iconic bell curve which comprises of a massive bulk of 'middle-class' values, and two thin tails - one of small left-wing values, and one of large right-wing values. The shape of the bell curve is unimodal, and its peak represents both the mode and the mean. Thomas Friedman, the famous New York Times columnist, recently asserted that we have entered a human era in which "Average is Over" . In this paper we present mathematical models for the phenomenon that Friedman highlighted. While the models are derived via different modeling approaches, they share a common foundation. Inherent tipping points cause the models to phase-shift from a 'normal' bell-shape statistical behavior to an 'anomalous' statistical behavior: the unimodal shape changes to an unbounded monotone shape, the mode vanishes, and the mean diverges. Hence: (i) there is an explosion of small values; (ii) large values become super-large; (iii) 'middle-class' values are wiped out, leaving an infinite rift between the small and the super large values; and (iv) "Average is Over" indeed.

  18. Mutual information-based feature selection for radiomics

    NASA Astrophysics Data System (ADS)

    Oubel, Estanislao; Beaumont, Hubert; Iannessi, Antoine

    2016-03-01

    Background The extraction and analysis of image features (radiomics) is a promising field in the precision medicine era, with applications to prognosis, prediction, and response to treatment quantification. In this work, we present a mutual information - based method for quantifying reproducibility of features, a necessary step for qualification before their inclusion in big data systems. Materials and Methods Ten patients with Non-Small Cell Lung Cancer (NSCLC) lesions were followed over time (7 time points in average) with Computed Tomography (CT). Five observers segmented lesions by using a semi-automatic method and 27 features describing shape and intensity distribution were extracted. Inter-observer reproducibility was assessed by computing the multi-information (MI) of feature changes over time, and the variability of global extrema. Results The highest MI values were obtained for volume-based features (VBF). The lesion mass (M), surface to volume ratio (SVR) and volume (V) presented statistically significant higher values of MI than the rest of features. Within the same VBF group, SVR showed also the lowest variability of extrema. The correlation coefficient (CC) of feature values was unable to make a difference between features. Conclusions MI allowed to discriminate three features (M, SVR, and V) from the rest in a statistically significant manner. This result is consistent with the order obtained when sorting features by increasing values of extrema variability. MI is a promising alternative for selecting features to be considered as surrogate biomarkers in a precision medicine context.

  19. Characterization of Industrial Wastewater Sludge in Oman from Three Different Regions and Recommendations for Alternate Reuse Applications

    PubMed Central

    BAAWAIN, Mahad S.; AL-JABRI, Mohsin; CHOUDRI, B.S.

    2015-01-01

    Background: Domestic and industrial wastewaters are mostly treated by biological process such as activated sludge, aerobic pond, and anaerobic treatment. This study focuses on characterizing the quality of sewage sludge in the Sultanate of Oman chosen from three industrial sewage treatment plants (STPs): Rusayl Industrial Estate (RSL.IE); Sohar Industrial Estate (SIE); and Raysut Industrial Estate (RIE). Methods: Samples of recycled activated sludge (RAS) and wasted activated sludge (WAS) were collected over a period of 12 months across above mentioned STPs. Parameters analyzed are electrical conductivity (EC), potential of hydrogen (pH), cations, anions and volatile content (VC). Results: The obtained values for pH and EC were low for both RAS and WAS samples, except EC values of RIE that was more than 1000 μS/cm. The range of VC percentages in RAS and WAS samples were 44 to 86% and 41 to 77%, respectively. The measured values for chloride, sulfate, nitrate and phosphate were higher than the other anions. Conclusion: The average values of the cations in RAS and WAS samples were within the Omani Standards, suitable for the re-use of sludge in agriculture except for Cd in RSL.IE. The study recommends that a regular maintenance should be performed at the studied STPs to prevent any accumulation of some harmful substances, which may affect the sludge quality, and the sludge drying beds should be large enough to handle the produced sludge for better management. PMID:26744704

  20. Mercury deposition in snow near an industrial emission source in the western U.S. and comparison to ISC3 model predictions

    USGS Publications Warehouse

    Abbott, M.L.; Susong, D.D.; Krabbenhoft, D.P.; Rood, A.S.

    2002-01-01

    Mercury (total and methyl) was evaluated in snow samples collected near a major mercury emission source on the Idaho National Engineering and Environmental Laboratory (INEEL) in southeastern Idaho and 160 km downwind in Teton Range in western Wyoming. The sampling was done to assess near-field (<12 km) deposition rates around the source, compare them to those measured in a relatively remote, pristine downwind location, and to use the measurements to develop improved, site-specific model input parameters for precipitation scavenging coefficient and the fraction of Hg emissions deposited locally. Measured snow water concentrations (ng L-1) were converted to deposition (ug m-2) using the sample location snow water equivalent. The deposition was then compared to that predicted using the ISC3 air dispersion/deposition model which was run with a range of particle and vapor scavenging coefficient input values. Accepted model statistical performance measures (fractional bias and normalized mean square error) were calculated for the different modeling runs, and the best model performance was selected. Measured concentrations close to the source (average = 5.3 ng L-1) were about twice those measured in the Teton Range (average = 2.7 ng L-1) which were within the expected range of values for remote background areas. For most of the sampling locations, the ISC3 model predicted within a factor of two of the observed deposition. The best modeling performance was obtained using a scavenging coefficient value for 0.25 ??m diameter particulate and the assumption that all of the mercury is reactive Hg(II) and subject to local deposition. A 0.1 ??m particle assumption provided conservative overprediction of the data, while a vapor assumption resulted in highly variable predictions. Partitioning a fraction of the Hg emissions to elemental Hg(0) (a U.S. EPA default assumption for combustion facility risk assessments) would have underpredicted the observed fallout.

  1. Numerical study of a confined slot impinging jet with nanofluids

    PubMed Central

    2011-01-01

    Background Heat transfer enhancement technology concerns with the aim of developing more efficient systems to satisfy the increasing demands of many applications in the fields of automotive, aerospace, electronic and process industry. A solution for obtaining efficient cooling systems is represented by the use of confined or unconfined impinging jets. Moreover, the possibility of increasing the thermal performances of the working fluids can be taken into account, and the introduction of nanoparticles in a base fluid can be considered. Results In this article, a numerical investigation on confined impinging slot jet working with a mixture of water and Al2O3 nanoparticles is described. The flow is turbulent and a constant temperature is applied on the impinging. A single-phase model approach has been adopted. Different geometric ratios, particle volume concentrations and Reynolds number have been considered to study the behavior of the system in terms of average and local Nusselt number, convective heat transfer coefficient and required pumping power profiles, temperature fields and stream function contours. Conclusions The dimensionless stream function contours show that the intensity and size of the vortex structures depend on the confining effects, given by H/W ratio, Reynolds number and particle concentrations. Furthermore, for increasing concentrations, nanofluids realize increasing fluid bulk temperature, as a result of the elevated thermal conductivity of mixtures. The local Nusselt number profiles show the highest values at the stagnation point, and the lowest at the end of the heated plate. The average Nusselt number increases for increasing particle concentrations and Reynolds numbers; moreover, the highest values are observed for H/W = 10, and a maximum increase of 18% is detected at a concentration equal to 6%. The required pumping power as well as Reynolds number increases and particle concentrations grow, which is almost 4.8 times greater than the values calculated in the case of base fluid. List of symbols PMID:21711743

  2. Carnegie Hubble Program: A Mid-Infrared Calibration of the Hubble Constant

    NASA Technical Reports Server (NTRS)

    Freedman, Wendy L.; Madore, Barry F.; Scowcroft, Victoria; Burns, Chris; Monson, Andy; Persson, S. Eric; Seibert, Mark; Rigby, Jane

    2012-01-01

    Using a mid-infrared calibration of the Cepheid distance scale based on recent observations at 3.6 micrometers with the Spitzer Space Telescope, we have obtained a new, high-accuracy calibration of the Hubble constant. We have established the mid-IR zero point of the Leavitt law (the Cepheid period-luminosity relation) using time-averaged 3.6 micrometers data for 10 high-metallicity, MilkyWay Cepheids having independently measured trigonometric parallaxes. We have adopted the slope of the PL relation using time-averaged 3.6micrometers data for 80 long-period Large Magellanic Cloud (LMC) Cepheids falling in the period range 0.8 < log(P) < 1.8.We find a new reddening-corrected distance to the LMC of 18.477 +/- 0.033 (systematic) mag. We re-examine the systematic uncertainties in H(sub 0), also taking into account new data over the past decade. In combination with the new Spitzer calibration, the systematic uncertainty in H(sub 0) over that obtained by the Hubble Space Telescope Key Project has decreased by over a factor of three. Applying the Spitzer calibration to the Key Project sample, we find a value of H(sub 0) = 74.3 with a systematic uncertainty of +/-2.1 (systematic) kilometers per second Mpc(sup -1), corresponding to a 2.8% systematic uncertainty in the Hubble constant. This result, in combination with WMAP7measurements of the cosmic microwave background anisotropies and assuming a flat universe, yields a value of the equation of state for dark energy, w(sub 0) = -1.09 +/- 0.10. Alternatively, relaxing the constraints on flatness and the numbers of relativistic species, and combining our results with those of WMAP7, Type Ia supernovae and baryon acoustic oscillations yield w(sub 0) = -1.08 +/- 0.10 and a value of N(sub eff) = 4.13 +/- 0.67, mildly consistent with the existence of a fourth neutrino species.

  3. Spatial distribution and metal contamination in the coastal sediments of Al-Khafji area, Arabian Gulf, Saudi Arabia.

    PubMed

    Alharbi, Talal; Alfaifi, Hussain; Almadani, Sattam A; El-Sorogy, Abdelbaset

    2017-11-13

    To document the spatial distribution and metal contamination in the coastal sediments of the Al-Khafji area in the northern part of the Saudi Arabian Gulf, 27 samples were collected for Al, V, Cr, Mn, Cu, Zn, Cd, Pb, Hg, Sr, As, Fe, Co, and Ni analysis using inductively coupled plasma-mass spectrometer (ICP-MS). The results revealed the following descending order of the metal concentrations: Sr > Fe > Al > As > Mn > Ni > V > Zn > Cr > Cu > Pb > Co > Hg > Cd. Average levels of enrichment factor of Sr, As, Hg, Cd, Ni, V, Cu, Co, and Pb were higher than 2 (218.10, 128.50, 80.94, 41.50, 12.31, 5.66, 2.95, 2.90, and 2.85, respectively) and that means the anthropogenic sources of these metals, while Al, Zn, Cr and Mn have enrichment factor less than 2, which implies natural sources. Average values of Sr, Hg, Cd, Cr, Ni, and As in the coastal sediments of Al-Khafji area were mostly higher than the values recorded from the background shale and earth crust and from those results along coasts of the Caspian Sea and the Mediterranean Sea. The highest levels of Cu in the northern part of the studied coastline might be due to Al-Khafji desalination plant, while levels of Al, Ni, Cr, Fe, Mn, Pb, and Zn in the central part may be a result of landfilling and industrial sewage. The highest levels of As, Cd, Co, Cu, Hg, and V in the southern part seem to be due to oil pollutants from Khafji Joint Operations (KJO). The higher values of Sr in the studied sediments in general and particularly in locality 7 could relate to the hypersalinity and aragonitic composition of the scleractinian corals abundant in that area.

  4. Lead Toxicity Risks in Gunshot Victims

    PubMed Central

    de Araújo, Gabriel Costa Serrão; Mourão, Natália Teixeira; Pinheiro, Igor Natário; Xavier, Analúcia Rampazzo; Gameiro, Vinicius Schott

    2015-01-01

    Background Gunshot wounds require surgeons to decide whether to remove or leave bullet fragments in the body. Surgeons also decide how to follow up with patients who have lead fragments retained in their body. Current literature recommends to remove only intra-articular fragments without the need for a follow-up for patients with the metal retained. Therefore, this study investigates chronic lead toxicity for gunshot wounds. Methods The study was performed in the metropolitan area of Rio de Janeiro/Brazil, between 2013 and 2015. It was a case-control study that included 45 victims of gunshot lesions with metallic fragments retained for more than 6 months. The 45 controls were matched for gender, age, and race. We compared the lead blood levels and frequency of symptoms. Results The control group had average blood lead levels of 2.17 μg/dL (95% Confidence Interval [CI]; 1.71–2.63) and median 2.1 μg/dL. The case group had average values of 9.01 μg/dL (CI; 6.07–11.96) and median values of 6.5 μg/dL with p-values < = 0.001. The case group reported the following more frequently: irritancy, bad mood, headache, memory losses, daylight drowsiness, myalgia, weakness, abdominal pain, joint pain, trembling, tingling limbs. There was statistical significance for the differences of symptoms frequencies and for odds ratio between groups. Conclusions Although the mean lead levels found were lower than the current laboratory references, low levels have been associated with both rising morbidity and mortality. The WHO stated: “There is no known level of lead exposure that is considered safe”. In conclusion, this work showed that bullets retained in the body are not innocuous. There are impacts in the blood lead levels and symptoms related to it, even with few fragments, extra-articular located or existing with low blood lead levels. PMID:26509498

  5. Translating HbA1c measurements into estimated average glucose values in pregnant women with diabetes.

    PubMed

    Law, Graham R; Gilthorpe, Mark S; Secher, Anna L; Temple, Rosemary; Bilous, Rudolf; Mathiesen, Elisabeth R; Murphy, Helen R; Scott, Eleanor M

    2017-04-01

    This study aimed to examine the relationship between average glucose levels, assessed by continuous glucose monitoring (CGM), and HbA 1c levels in pregnant women with diabetes to determine whether calculations of standard estimated average glucose (eAG) levels from HbA 1c measurements are applicable to pregnant women with diabetes. CGM data from 117 pregnant women (89 women with type 1 diabetes; 28 women with type 2 diabetes) were analysed. Average glucose levels were calculated from 5-7 day CGM profiles (mean 1275 glucose values per profile) and paired with a corresponding (±1 week) HbA 1c measure. In total, 688 average glucose-HbA 1c pairs were obtained across pregnancy (mean six pairs per participant). Average glucose level was used as the dependent variable in a regression model. Covariates were gestational week, study centre and HbA 1c . There was a strong association between HbA 1c and average glucose values in pregnancy (coefficient 0.67 [95% CI 0.57, 0.78]), i.e. a 1% (11 mmol/mol) difference in HbA 1c corresponded to a 0.67 mmol/l difference in average glucose. The random effects model that included gestational week as a curvilinear (quadratic) covariate fitted best, allowing calculation of a pregnancy-specific eAG (PeAG). This showed that an HbA 1c of 8.0% (64 mmol/mol) gave a PeAG of 7.4-7.7 mmol/l (depending on gestational week), compared with a standard eAG of 10.2 mmol/l. The PeAG associated with maintaining an HbA 1c level of 6.0% (42 mmol/mol) during pregnancy was between 6.4 and 6.7 mmol/l, depending on gestational week. The HbA 1c -average glucose relationship is altered by pregnancy. Routinely generated standard eAG values do not account for this difference between pregnant and non-pregnant individuals and, thus, should not be used during pregnancy. Instead, the PeAG values deduced in the current study are recommended for antenatal clinical care.

  6. Grey-Markov prediction model based on background value optimization and central-point triangular whitenization weight function

    NASA Astrophysics Data System (ADS)

    Ye, Jing; Dang, Yaoguo; Li, Bingjun

    2018-01-01

    Grey-Markov forecasting model is a combination of grey prediction model and Markov chain which show obvious optimization effects for data sequences with characteristics of non-stationary and volatility. However, the state division process in traditional Grey-Markov forecasting model is mostly based on subjective real numbers that immediately affects the accuracy of forecasting values. To seek the solution, this paper introduces the central-point triangular whitenization weight function in state division to calculate possibilities of research values in each state which reflect preference degrees in different states in an objective way. On the other hand, background value optimization is applied in the traditional grey model to generate better fitting data. By this means, the improved Grey-Markov forecasting model is built. Finally, taking the grain production in Henan Province as an example, it verifies this model's validity by comparing with GM(1,1) based on background value optimization and the traditional Grey-Markov forecasting model.

  7. Modeling patterns of coral bleaching at a remote Central Pacific atoll.

    PubMed

    Williams, Gareth J; Knapp, Ingrid S; Maragos, James E; Davy, Simon K

    2010-09-01

    A mild bleaching event (9.2% prevalence) at Palmyra Atoll occurred in response to the 2009 ENSO, when mean water temperature reached 29.8-30.1 degrees C. Prevalence among both abundant and sparse taxa varied with no clear pattern in susceptibility relating to coral morphology. Seven taxon-specific models showed that turbidity exacerbated while prior exposure to higher background temperatures alleviated bleaching, with these predictors explaining an average 16.3% and 11.5% variation in prevalence patterns, respectively. Positive associations occurred between bleaching prevalence and both immediate temperature during the bleaching event (average 8.4% variation explained) and increased sand cover (average 3.7%). Despite these associations, mean unexplained variation in prevalence equalled 59%. Lower bleaching prevalence in areas experiencing higher background temperatures suggests acclimation to temperature stress among several coral genera, while WWII modifications may still be impacting the reefs via shoreline sediment re-distribution and increased turbidity, exacerbating coral bleaching susceptibility during periods of high temperature stress. Copyright 2010 Elsevier Ltd. All rights reserved.

  8. Characteristics of Fe Ablation Trials Observed During the 1998 Leonid Meteor Shower

    NASA Technical Reports Server (NTRS)

    Chu, Xin-Zhao; Pan, Wei-Lin; Papen, George; Swenson, Gary; Gardner, Chester S.; Jenniskens, Peter; DeVincenzi, Donald L. (Technical Monitor)

    2000-01-01

    Eighteen Fe ablation trails were observed during the 17/18 Nov 1998 Leonid meteor shower with an airborne Fe lidar aboard the National Simulation Facility/National Center for Atmospheric Research (NSF/NCAR) Electra aircraft over Okinawa. The average altitude of the 18 trails from the high velocity (72 km/s) Leonid meteors, 95.67 +/- 0.93 km, is approximately 6.7 km higher than previously observed for slower (approx. 30 km/s) sporadic meteors. This height difference is consistent with the assumption that meteors ablate when the kinetic energy imparted to the atmosphere reaches a critical threshold. The average age of the Fe trails, determined by a diffusion model, is 10.1 min. The youngest ages were observed below 92 km and above 98 km where chemistry and diffusion dominate, respectively. The average abundance of the trails is ten percent of the abundance of the background Fe layer. Observations suggest that the 1998 Leonid shower did not have a significant impact on the abundance of the background Fe layer.

  9. Assessment of cadmium (Cd) concentration in arable soil in China.

    PubMed

    Zhang, Xiuying; Chen, Dongmei; Zhong, Taiyang; Zhang, Xiaomin; Cheng, Min; Li, Xinhui

    2015-04-01

    Cadmium (Cd) concentration in arable soil has drawn broad public attention due to its direct effect on Cd concentration in food. However, there have been few studies of surveying Cd accumulation on the national scale in China. This paper collected 486 studies of Cd concentrations in Chinese arable soil. The results showed that the average Cd concentration was 0.27 mg/kg, higher than its background value, indicating that Cd had been introduced into arable soil by human activity. The Cd concentrations in areas of mining and smelting, urban areas, and areas irrigated by wastewater were obviously higher than that in remote areas. Spatially, Cd concentrations were lower in the north than those in the south, and many hotspots existed throughout China due to mining and smelting activities. Most Cd in the arable soil were accumulated from external sources in all investigated provinces except Ningxia Hui Autonomous Region.

  10. Tropospheric and lower stratospheric vertical profiles of ethane and acetylene

    NASA Technical Reports Server (NTRS)

    Cronn, D.; Robinson, E.

    1979-01-01

    The first known vertical distributions of ethane and acetylene which extend into the lower stratosphere are reported. The average upper tropospheric concentrations, between 20,000 ft and 35,000 ft, near 37 deg N-123 deg W were 1.2 micrograms/cu m (1.0 ppb) for ethane and 0.24 micrograms /cu m (0.23 ppb) for acetylene while the values near 9 N-80 W were 0.95 micrograms/cu m (0.77 ppb) and 0.09 micrograms/cu m (0.09 ppb), respectively. Detectable quantities of both ethane and acetylene are present in the lower stratosphere. There is a sharp decrease in the levels of these two compounds as one crosses the tropopause and ascends into the lower stratosphere. The observed levels of ethane and acetylene may allow some impact on the background chemistry of the troposphere and stratosphere.

  11. Rational group decision making: A random field Ising model at T = 0

    NASA Astrophysics Data System (ADS)

    Galam, Serge

    1997-02-01

    A modified version of a finite random field Ising ferromagnetic model in an external magnetic field at zero temperature is presented to describe group decision making. Fields may have a non-zero average. A postulate of minimum inter-individual conflicts is assumed. Interactions then produce a group polarization along one very choice which is however randomly selected. A small external social pressure is shown to have a drastic effect on the polarization. Individual bias related to personal backgrounds, cultural values and past experiences are introduced via quenched local competing fields. They are shown to be instrumental in generating a larger spectrum of collective new choices beyond initial ones. In particular, compromise is found to results from the existence of individual competing bias. Conflict is shown to weaken group polarization. The model yields new psychosociological insights about consensus and compromise in groups.

  12. Metal pollution in Al-Khobar seawater, Arabian Gulf, Saudi Arabia.

    PubMed

    Alharbi, Talal; Alfaifi, Hussain; El-Sorogy, Abdelbaset

    2017-06-15

    In order to assess heavy metals pollution along the Al-Khobar coastline, 30 seawater samples and 15 sediment ones were collected for Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Hg and Pb analysis by Inductively Coupled Plasma-Mass Spectrometer (ICP-MS). The analysis indicated a southward decreasing pattern in most heavy metal concentrations and the average values of Zn, Fe, Mn, Cu, As and Cr were higher than the ones reported from some worldwide seas and gulfs. Most of the highest levels were recorded within the bays and were related with in situ under sediments especially that composed of clays and very fine sands, and in localities characterized with anthropogenic activities like landfilling, desalination plants, fishing boats, oil spills and solid rubbish. The results of the present study provide useful background for further marine investigation and management in the Arabian Gulf region. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Large-scale structure after COBE: Peculiar velocities and correlations of cold dark matter halos

    NASA Technical Reports Server (NTRS)

    Zurek, Wojciech H.; Quinn, Peter J.; Salmon, John K.; Warren, Michael S.

    1994-01-01

    Large N-body simulations on parallel supercomputers allow one to simultaneously investigate large-scale structure and the formation of galactic halos with unprecedented resolution. Our study shows that the masses as well as the spatial distribution of halos on scales of tens of megaparsecs in a cold dark matter (CDM) universe with the spectrum normalized to the anisotropies detected by Cosmic Background Explorer (COBE) is compatible with the observations. We also show that the average value of the relative pairwise velocity dispersion sigma(sub v) - used as a principal argument against COBE-normalized CDM models-is significantly lower for halos than for individual particles. When the observational methods of extracting sigma(sub v) are applied to the redshift catalogs obtained from the numerical experiments, estimates differ significantly between different observation-sized samples and overlap observational estimates obtained following the same procedure.

  14. Primordial inhomogeneities in the expanding universe. II - General features of spherical models at late times

    NASA Technical Reports Server (NTRS)

    Olson, D. W.; Silk, J.

    1979-01-01

    This paper studies the density profile that forms around a spherically symmetric bound central core immersed in a homogeneous-background k = 0 or k = -1 Friedmann-Robertson-Walker cosmological model, with zero pressure. Although the density profile in the linearized regime is almost arbitrary, in the nonlinear regime certain universal features of the density profile are obtained that are independent of the details of the initial conditions. The formation of 'halos' ('holes') with densities greater than (less than) the average cosmological density is discussed. It is shown that in most regions 'halos' form, and universal values are obtained for the slope of the ln (density)-ln (radius) profile in those 'halos' at late times, independently of the shape of the initial density profile. Restrictions are derived on where it is possible for 'holes' to exist at late times and on how such 'holes' must have evolved.

  15. Partial correlation-based functional connectivity analysis for functional near-infrared spectroscopy signals

    NASA Astrophysics Data System (ADS)

    Akın, Ata

    2017-12-01

    A theoretical framework, a partial correlation-based functional connectivity (PC-FC) analysis to functional near-infrared spectroscopy (fNIRS) data, is proposed. This is based on generating a common background signal from a high passed version of fNIRS data averaged over all channels as the regressor in computing the PC between pairs of channels. This approach has been employed to real data collected during a Stroop task. The results show a strong significance in the global efficiency (GE) metric computed by the PC-FC analysis for neutral, congruent, and incongruent stimuli (NS, CS, IcS; GEN=0.10±0.009, GEC=0.11±0.01, GEIC=0.13±0.015, p=0.0073). A positive correlation (r=0.729 and p=0.0259) is observed between the interference of reaction times (incongruent-neutral) and interference of GE values (GEIC-GEN) computed from [HbO] signals.

  16. ["Piggyback" shot: ballistic parameters of two simultaneously discharged airgun pellets].

    PubMed

    Frank, Matthias; Schönekess, Holger C; Grossjohann, Rico; Ekkernkamp, Axel; Bockholdt, Britta

    2014-01-01

    Green and Good reported an uncommon case of homicide committed with an air rifle in 1982 (Am. J. Forensic Med. Pathol. 3: 361-365). The fatal wound was unusual in that two airgun pellets were loaded in so-called "piggyback" fashion into a single shot air rifle. Lack of further information on the ballistic characteristics of two airgun pellets as opposed to one conventionally loaded projectile led to this investigation. The mean kinetic energy (E) of the two pellets discharged in "piggyback" fashion was E = 3.6 J and E = 3.4 J, respectively. In comparison, average kinetic energy values of E = 12.5 J were calculated for conventionally discharged single diabolo pellets. Test shots into ballistic soap confirmed the findings of a single entrance wound as reported by Green and Good. While the ballistic background of pellets discharged in "piggyback" fashion could be clarified, the reason behind this mode of shooting remains unclear.

  17. Study on negative incident photon-to-electron conversion efficiency of quantum dot-sensitized solar cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Chunhui; Wu, Huijue; Zhu, Lifeng

    2014-02-15

    Recently, negative signals are frequently observed during the measuring process of monochromatic incident photon-to-electron conversion efficiency (IPCE) for sensitized solar cells by DC method. This phenomenon is confusing and hindering the reasonable evaluation of solar cells. Here, cause of negative IPCE values is studied by taking quantum dot-sensitized solar cell (QDSC) as an example, and the accurate measurement method to avoid the negative value is suggested. The negative background signals of QDSC without illumination are found the direct cause of the negative IPCE values by DC method. Ambient noise, significant capacitance characteristics, and uncontrolled electrochemical reaction all can lead tomore » the negative background signals. When the photocurrent response of device under monochromatic light illumination is relatively weak, the actual photocurrent signals will be covered by the negative background signals and the resulting IPCE values will appear negative. To improve the signal-to-noise ratio, quasi-AC method is proposed for IPCE measurement of solar cells with weak photocurrent response based on the idea of replacing the absolute values by the relative values.« less

  18. California black oak response to nitrogen amendment at a high O3, nitrogen-saturated site

    Treesearch

    Nancy Grulke; W. Dobrowolski; P. Mingus; M.E. Fenn

    2005-01-01

    In a nitrogen (N) saturated forest downwind from Los Angeles, California, the cumulative response to long-term background-N and N-amendment on black oak (Quercus kelloggii) was described in a below-average and average precipitation year. Monthly measurements of leaf and branch growth, gas exchange, and canopy health attributes were conducted. The...

  19. Muon simulations for Super-Kamiokande, KamLAND, and CHOOZ

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tang, Alfred; Horton-Smith, Glenn; Kudryavtsev, Vitaly A.

    2006-09-01

    Muon backgrounds at Super-Kamiokande, KamLAND, and CHOOZ are calculated using MUSIC. A modified version of the Gaisser sea-level muon distribution and a well-tested Monte Carlo integration method are introduced. Average muon energy, flux, and rate are tabulated. Plots of average energy and angular distributions are given. Implications for muon tracker design in future experiments are discussed.

  20. Combined Study of Snow Depth Determination and Winter Leaf Area Index Retrieval by Unmanned Aerial Vehicle Photogrammetry

    NASA Astrophysics Data System (ADS)

    Lendzioch, Theodora; Langhammer, Jakub; Jenicek, Michal

    2017-04-01

    A rapid and robust approach using Unmanned Aerial Vehicle (UAV) digital photogrammetry was performed for evaluating snow accumulation over different small localities (e.g. disturbed forest and open area) and for indirect field measurements of Leaf Area Index (LAI) of coniferous forest within the Šumava National Park, Czech Republic. The approach was used to reveal impacts related to changes in forest and snowpack and to determine winter effective LAI for monitoring the impact of forest canopy metrics on snow accumulation. Due to the advancement of the technique, snow depth and volumetric changes of snow depth over these selected study areas were estimated at high spatial resolution (1 cm) by subtracting a snow-free digital elevation model (DEM) from a snow-covered DEM. Both, downward-looking UAV images and upward-looking digital hemispherical photography (DHP), and additional widely used LAI-2200 canopy analyser measurements were applied to determine the winter LAI, controlling interception and transmitting radiation. For the performance of downward-looking UAV images the snow background instead of the sky fraction was used. The reliability of UAV-based LAI retrieval was tested by taking an independent data set during the snow cover mapping campaigns. The results showed the potential of digital photogrammetry for snow depth mapping and LAI determination by UAV techniques. The average difference obtained between ground-based and UAV-based measurements of snow depth was 7.1 cm with higher values obtained by UAV. The SD of 22 cm for the open area seemed competitive with the typical precision of point measurements. In contrast, the average difference in disturbed forest area was 25 cm with lower values obtained by UAV and a SD of 36 cm, which is in agreement with other studies. The UAV-based LAI measurements revealed the lowest effective LAI values and the plant canopy analyser LAI-2200 the highest effective LAI values. The biggest bias of effective LAI was observed between LAI-2200 and UAV-based analyses. Since the LAI parameter is important for snowpack modelling, this method presents the potential of simplifying LAI retrieval and mapping of snow dynamics while reducing running costs and time.

  1. Simulating a base population in honey bee for molecular genetic studies

    PubMed Central

    2012-01-01

    Background Over the past years, reports have indicated that honey bee populations are declining and that infestation by an ecto-parasitic mite (Varroa destructor) is one of the main causes. Selective breeding of resistant bees can help to prevent losses due to the parasite, but it requires that a robust breeding program and genetic evaluation are implemented. Genomic selection has emerged as an important tool in animal breeding programs and simulation studies have shown that it yields more accurate breeding value estimates, higher genetic gain and low rates of inbreeding. Since genomic selection relies on marker data, simulations conducted on a genomic dataset are a pre-requisite before selection can be implemented. Although genomic datasets have been simulated in other species undergoing genetic evaluation, simulation of a genomic dataset specific to the honey bee is required since this species has a distinct genetic and reproductive biology. Our software program was aimed at constructing a base population by simulating a random mating honey bee population. A forward-time population simulation approach was applied since it allows modeling of genetic characteristics and reproductive behavior specific to the honey bee. Results Our software program yielded a genomic dataset for a base population in linkage disequilibrium. In addition, information was obtained on (1) the position of markers on each chromosome, (2) allele frequency, (3) χ2 statistics for Hardy-Weinberg equilibrium, (4) a sorted list of markers with a minor allele frequency less than or equal to the input value, (5) average r2 values of linkage disequilibrium between all simulated marker loci pair for all generations and (6) average r2 value of linkage disequilibrium in the last generation for selected markers with the highest minor allele frequency. Conclusion We developed a software program that takes into account the genetic and reproductive biology specific to the honey bee and that can be used to constitute a genomic dataset compatible with the simulation studies necessary to optimize breeding programs. The source code together with an instruction file is freely accessible at http://msproteomics.org/Research/Misc/honeybeepopulationsimulator.html PMID:22520469

  2. Geographical Detector-Based Risk Factors Assessment of the Hand-Foot-Mouth Disease in China

    NASA Astrophysics Data System (ADS)

    Huang, J.

    2017-12-01

    Background: Hand, foot and mouth disease(HFMD) is a common infectious disease, causing thousands of deaths among children in China. This study focused on analyzing the impacts of different populations and different industry structures on HFMD incidence in China. Methods: We collected HFMD cases from 2307 counties during May 2008 in China. The potential risk factors included: monthly mean temperature, monthly mean relative humidity, monthly precipitation, different population density, different industry structures. Geographical detector technique was used to analyze the main and interactive effect of potential risk factors on HFMD incidence. Result: Using risk detector, we found the most serious HFMD incidence mainly located in the Yangtze River delta and the Pearl River delta. When the temperature was high, the incidence of HFMD was also high. This finding indicates that there is a correlation between monthly mean temperature and the incidence of HFMD. Similar analysis was undertaken to analyze the correlation between other variables and the incidence of HFMD using the risk detector. Using factor detector, we found the effect of risk factors on the incidence of HFMD, and this was ranked by PD value as follows: density of children aged 0-9 years (0.25) > tertiary industry (0.23) > GDP (0.20) >middle school student density (0.13) > relative humidity (0.12) >average temperature (0.11) >first industry (0.05). Using ecological detector, we found that child density, tertiary industry, and GDP had a strong effect on the incidence of HFMD. Using interactive detector, we found that the interactive PD value of tertiary industry and child population density was 0.42, which of GDP and tertiary industry was 0.34, that of child population density and GDP was 0.35, and that of average temperature and relative humidity was 0.28. All of these interactive PD values appeared to be higher than any PD value of sole risk factors. The combinations of the above-mentioned risk factors could effectively explain spatial variability of the incidence of HFMD in China.

  3. Geochemical characterization and Redox signals of the uppermost Barremian - lowest Aptian of the Eastern Prada Quarry section, Organyà Basin, south-central Pyrenees, Catalunya, Spain

    NASA Astrophysics Data System (ADS)

    Llaguno, J. R.; Maurrasse, F. J.

    2016-12-01

    Here we present the results of a high-resolution, multiproxy study of a 29 m section of dark nodular limestones and marlstones of the Eastern Prada Mountain Quarry section. The layers yield low bioturbation index (2-3) and TOC up to 1.88 wt. %, with microfacies of dark micrite, and isotropic fabric. Allochems consist of rare ostracods, radiolaria, fragments of echinoderms, ammonites, gastropods, benthic and planktic foraminifera. Globigerinelloides blowi indicates a Barremian-early Aptian age. Porosity consists of vugs filled with apparent bitumen throughout the section. Qualitative EDS analyses indicate CaCO3 predominates in the matrix, in agreement with smear slides showing abundance of calcareous nannofossils, mostly nannoconid fragments. δ13Corg values vary from -26.24 ‰ at 0.7 m, to -23.78 ‰, ( 2.46 ‰ change) at 18.04 m, with higher fluctuations up to 27 m. δ15N values range from 1.82 ‰ to 5.95 ‰ positively correlated with the δ13Corg, especially between 18 m - 27 m. Biomarkers from 16 samples show dominance of short chain n-alkanes (

  4. Identifying Canadian Freshwater Fishes through DNA Barcodes

    PubMed Central

    Hubert, Nicolas; Hanner, Robert; Holm, Erling; Mandrak, Nicholas E.; Taylor, Eric; Burridge, Mary; Watkinson, Douglas; Dumont, Pierre; Curry, Allen; Bentzen, Paul; Zhang, Junbin; April, Julien; Bernatchez, Louis

    2008-01-01

    Background DNA barcoding aims to provide an efficient method for species-level identifications using an array of species specific molecular tags derived from the 5′ region of the mitochondrial cytochrome c oxidase I (COI) gene. The efficiency of the method hinges on the degree of sequence divergence among species and species-level identifications are relatively straightforward when the average genetic distance among individuals within a species does not exceed the average genetic distance between sister species. Fishes constitute a highly diverse group of vertebrates that exhibit deep phenotypic changes during development. In this context, the identification of fish species is challenging and DNA barcoding provide new perspectives in ecology and systematics of fishes. Here we examined the degree to which DNA barcoding discriminate freshwater fish species from the well-known Canadian fauna, which currently encompasses nearly 200 species, some which are of high economic value like salmons and sturgeons. Methodology/Principal Findings We bi-directionally sequenced the standard 652 bp “barcode” region of COI for 1360 individuals belonging to 190 of the 203 Canadian freshwater fish species (95%). Most species were represented by multiple individuals (7.6 on average), the majority of which were retained as voucher specimens. The average genetic distance was 27 fold higher between species than within species, as K2P distance estimates averaged 8.3% among congeners and only 0.3% among concpecifics. However, shared polymorphism between sister-species was detected in 15 species (8% of the cases). The distribution of K2P distance between individuals and species overlapped and identifications were only possible to species group using DNA barcodes in these cases. Conversely, deep hidden genetic divergence was revealed within two species, suggesting the presence of cryptic species. Conclusions/Significance The present study evidenced that freshwater fish species can be efficiently identified through the use of DNA barcoding, especially the species complex of small-sized species, and that the present COI library can be used for subsequent applications in ecology and systematics. PMID:22423312

  5. Medical Students’ Perception of Their Educational Environment

    PubMed Central

    Pai, Preethi G; Menezes, Vishma; Srikanth; Subramanian, Atreya M.; Shenoy, Jnaneshwara P.

    2014-01-01

    Background: Students’ perception of the environment within which they study has shown to have a significant impact on their behavior, academic progress and sense of well-being. This study was undertaken to evaluate the students’ perception of their learning environment in an Indian medical school following traditional curricula and to study differences, if any, between the students according to the stages of medical education, i.e., the pre-clinical and clinical stages. Methodology: In the present study, the Dundee Ready Education Environment Measure (DREEM) inventory was administered to undergraduate medical students of first (n = 227), third (n = 175), fifth (n = 171) and seventh (n = 123) semesters. Scores obtained were expressed as mean ± Standard Deviation (SD) and analyzed using one-way ANOVA and Dunnett’s test. P-value < 0.05 was considered as significant. Results: The mean DREEM score for our medical school was 123/200.The first-year students were found to be more satisfied with learning environment (indicated by their higher DREEM score) compared to other semester students. Progressive decline in scores with each successive semester was observed. Evaluating the sub-domains of perception, the registrars in all semesters had a more positive perception of learning (Average mean score: 29.44), their perception of course organizers moved in the right direction (Average mean score: 26.86), their academic self-perception was more on the positive side (Average mean score: 20.14), they had a more positive perception of atmosphere (Average mean score: 29.07) and their social self-perception could be graded as not too bad (Average mean score: 17.02). Conclusion: The present study revealed that all the groups of students perceived their learning environment positively. However, a few problematic areas of learning environment were perceived such as: students were stressed more often; they felt that the course organizers were authoritarian and emphasized factual learning. Implementing more problem-based learning, student counseling and workshops on teaching-learning for educators might enable us to remedy and enrich our learning environment. PMID:24596737

  6. Widespread Climate Change in the Himalayas and Associated Changes in Local Ecosystems

    PubMed Central

    Shrestha, Uttam Babu; Gautam, Shiva; Bawa, Kamaljit S.

    2012-01-01

    Background Climate change in the Himalayas, a biodiversity hotspot, home of many sacred landscapes, and the source of eight largest rivers of Asia, is likely to impact the well-being of ∼20% of humanity. However, despite the extraordinary environmental, cultural, and socio-economic importance of the Himalayas, and despite their rapidly increasing ecological degradation, not much is known about actual changes in the two most critical climatic variables: temperature and rainfall. Nor do we know how changes in these parameters might impact the ecosystems including vegetation phenology. Methodology/Principal Findings By analyzing temperature and rainfall data, and NDVI (Normalized Difference Vegetation Index) values from remotely sensed imagery, we report significant changes in temperature, rainfall, and vegetation phenology across the Himalayas between 1982 and 2006. The average annual mean temperature during the 25 year period has increased by 1.5°C with an average increase of 0.06°C yr−1. The average annual precipitation has increased by 163 mm or 6.52 mmyr−1. Since changes in temperature and precipitation are immediately manifested as changes in phenology of local ecosystems, we examined phenological changes in all major ecoregions. The average start of the growing season (SOS) seems to have advanced by 4.7 days or 0.19 days yr−1 and the length of growing season (LOS) appears to have advanced by 4.7 days or 0.19 days yr−1, but there has been no change in the end of the growing season (EOS). There is considerable spatial and seasonal variation in changes in climate and phenological parameters. Conclusions/Significance This is the first time that large scale climatic and phenological changes at the landscape level have been documented for the Himalayas. The rate of warming in the Himalayas is greater than the global average, confirming that the Himalayas are among the regions most vulnerable to climate change. PMID:22615804

  7. Greenhouse gas emissions of realistic dietary choices in Denmark: the carbon footprint and nutritional value of dairy products

    PubMed Central

    Werner, Louise Bruun; Flysjö, Anna; Tholstrup, Tine

    2014-01-01

    Background Dairy products are important in a healthy diet due to their high nutritional value; they are, however, associated with relatively large greenhouse gas emissions (GHGE) per kg product. When discussing the need to reduce the GHGE caused by the food system, it is crucial to consider the nutritional value of alternative food choices. Objective The objective of this study was to elucidate the role of dairy products in overall nutrition and to clarify the effects of dietary choices on GHGE, and to combine nutritional value and GHGE data. Methods We created eight dietary scenarios with different quantity of dairy products using data from the Danish National Dietary Survey (1995–2006). Nutrient composition and GHGE data for 71 highly consumed foods were used to estimate GHGE and nutritional status for each dietary scenario. An index was used to estimate nutrient density in relation to nutritional recommendation and climate impact for solid food items; high index values were those with the highest nutrient density scores in relation to the GHGE. Results The high-dairy scenario resulted in 27% higher protein, 13% higher vitamin D; 55% higher calcium; 48% higher riboflavin; and 18% higher selenium than the non-dairy scenario. There was a significant correlation between changes in calcium and changes in vitamin D, selenium, and riboflavin content (P=0.0001) throughout all of the diets. The estimated GHGE for the dietary scenario with average-dairy consumption was 4,631 g CO2e/day. Conclusions When optimizing a diet with regard to sustainability, it is crucial to account for the nutritional value and not solely focus on impact per kg product. Excluding dairy products from the diet does not necessarily mitigate climate change but in contrast may have nutritional consequences. PMID:24959114

  8. 7 CFR 59.200 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... these same swine. Average lean percentage. The term “average lean percentage” means the value equal to the average percentage of the carcass weight comprised of lean meat for the swine slaughtered during the applicable reporting period. Whenever the packer changes the manner in which the average lean...

  9. 7 CFR 59.200 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... these same swine. Average lean percentage. The term “average lean percentage” means the value equal to the average percentage of the carcass weight comprised of lean meat for the swine slaughtered during the applicable reporting period. Whenever the packer changes the manner in which the average lean...

  10. R-Matrix Analysis of Structures in Economic Indices: from Nuclear Reactions to High-Frequency Trading

    NASA Astrophysics Data System (ADS)

    Firk, Frank W. K.

    2014-03-01

    It is shown that the R-matrix theory of nuclear reactions is a viable mathematical theory for the description of the fine, intermediate and gross structure observed in the time-dependence of economic indices in general, and the daily Dow Jones Industrial Average in particular. A Lorentzian approximation to R-matrix theory is used to analyze the complex structures observed in the Dow Jones Industrial Average on a typical trading day. Resonant structures in excited nuclei are characterized by the values of their fundamental strength function, (average total width of the states)/(average spacing between adjacent states). Here, values of the ratios (average lifetime of individual states of a given component of the daily Dow Jones Industrial Average)/(average interval between the adjacent states) are determined. The ratios for the observed fine and intermediate structure of the index are found to be essentially constant throughout the trading day. These quantitative findings are characteristic of the highly statistical nature of many-body, strongly interacting systems, typified by daily trading. It is therefore proposed that the values of these ratios, determined in the first hour-or-so of trading, be used to provide valuable information concerning the likely performance of the fine and intermediate components of the index for the remainder of the trading day.

  11. Neither fish nor fowl: A perceived mismatch in norms and values between oneself, other students, and people back home undermines adaptation to university.

    PubMed

    de Vreeze, Jort; Matschke, Christina; Cress, Ulrike

    2018-03-12

    Students from low social-class background often struggle to adapt to university. Previous research shows that perceived incompatibility between social-class background identity and student identity is one reason, but little is known about the underlying causes of identity incompatibility. In three studies, we expected and found that students with low subjective social-class background perceived their values differently from other students, but also differently from people back home, and both increased identity incompatibility. Identity incompatibility negatively affected the student identity. Additionally, the current research also identifies specific patterns of norm and value differences that are prone to perceived identity incompatibility. The findings demonstrate that perceived differences in values from both groups are important mechanisms for identity incompatibility induced by the transition to university that may affect student identities and potentially their university trajectories. © 2018 The British Psychological Society.

  12. Measurements of air dose rates in and around houses in the Fukushima Prefecture in Japan after the Fukushima accident.

    PubMed

    Matsuda, Norihiro; Mikami, Satoshi; Sato, Tetsuro; Saito, Kimiaki

    2017-01-01

    Measurements of air dose rates for 192 houses in a less contaminated area (<0.5 μSv h -1 ) of the Fukushima Prefecture in Japan were conducted in both living rooms and/or bedrooms using optically stimulated luminescence (OSL) dosimeters and around the houses via a man-borne survey at intervals of several meters. The relation of the two air dose rates (inside and outside) for each house, including the background from natural radionuclides, was divided into several categories, determined by construction materials (light and heavy) and floor number, with the dose reduction factors being expressed as the ratio of the dose inside to that outside the house. For wooden and lightweight steel houses (classed as light), the dose rates inside and outside the houses showed a positive correlation and linear regression with a slope-intercept form due to the natural background, although the degree of correlation was not very high. The regression coefficient, i.e., the average dose reduction factor, was 0.38 on the first floor and 0.49 on the second floor. It was found that the contribution of natural radiation cannot be neglected when we consider dose reduction factors in less contaminated areas. The reductions in indoor dose rates are observed because a patch of ground under each house is not contaminated (this is the so-called uncontaminated effect) since the shielding capability of light construction materials is typically low. For reinforced steel-framed concrete houses (classed as heavy), the dose rates inside the houses did not show a correlation with those outside the houses due to the substantial shielding capability of these materials. The average indoor dose rates were slightly higher than the arithmetic mean value of the outdoor dose rates from the natural background because concrete acts as a source of natural radionuclides. The characteristics of the uncontaminated effect were clarified through Monte Carlo simulations. It was found that there is a great variation in air dose rates even within one house, depending on the height of the area and its closeness to the outside boundary. Measurements of outdoor dose rates required consideration of local variations depending on the environment surrounding each house. The representative value was obtained from detailed distributions of air dose rates around the house, as measured by a man-borne survey. Therefore, it is imperative to recognize that dose reduction factors fluctuate in response to various factors such as the size and shape of a house, construction materials acting as a shield and as sources, position (including height) within a room, floor number, total number of floors, and surrounding environment. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. First Nuclear DNA Amounts in more than 300 Angiosperms

    PubMed Central

    ZONNEVELD, B. J. M.; LEITCH, I. J.; BENNETT, M. D.

    2005-01-01

    • Background and Aims Genome size (DNA C-value) data are key biodiversity characters of fundamental significance used in a wide variety of biological fields. Since 1976, Bennett and colleagues have made scattered published and unpublished genome size data more widely accessible by assembling them into user-friendly compilations. Initially these were published as hard copy lists, but since 1997 they have also been made available electronically (see the Plant DNA C-values database www.kew.org/cval/homepage.html). Nevertheless, at the Second Plant Genome Size Meeting in 2003, Bennett noted that as many as 1000 DNA C-value estimates were still unpublished and hence unavailable. Scientists were strongly encouraged to communicate such unpublished data. The present work combines the databasing experience of the Kew-based authors with the unpublished C-values produced by Zonneveld to make a large body of valuable genome size data available to the scientific community. • Methods C-values for angiosperm species, selected primarily for their horticultural interest, were estimated by flow cytometry using the fluorochrome propidium iodide. The data were compiled into a table whose form is similar to previously published lists of DNA amounts by Bennett and colleagues. • Key Results and Conclusions The present work contains C-values for 411 taxa including first values for 308 species not listed previously by Bennett and colleagues. Based on a recent estimate of the global published output of angiosperm DNA C-value data (i.e. 200 first C-value estimates per annum) the present work equals 1·5 years of average global published output; and constitutes over 12 % of the latest 5-year global target set by the Second Plant Genome Size Workshop (see www.kew.org/cval/workshopreport.html). Hopefully, the present example will encourage others to unveil further valuable data which otherwise may lie forever unpublished and unavailable for comparative analyses. PMID:15905300

  14. The Effect of Fuel Quality on Carbon Dioxide and Nitrogen Oxide Emissions, While Burning Biomass and RDF

    NASA Astrophysics Data System (ADS)

    Kalnacs, J.; Bendere, R.; Murasovs, A.; Arina, D.; Antipovs, A.; Kalnacs, A.; Sprince, L.

    2018-02-01

    The article analyses the variations in carbon dioxide emission factor depending on parameters characterising biomass and RDF (refuse-derived fuel). The influence of moisture, ash content, heat of combustion, carbon and nitrogen content on the amount of emission factors has been reviewed, by determining their average values. The options for the improvement of the fuel to result in reduced emissions of carbon dioxide and nitrogen oxide have been analysed. Systematic measurements of biomass parameters have been performed, by determining their average values, seasonal limits of variations in these parameters and their mutual relations. Typical average values of RDF parameters and limits of variations have been determined.

  15. Study of average valence and valence electron distribution of several oxides using X-ray photoelectron spectra

    NASA Astrophysics Data System (ADS)

    Ding, L. L.; Wu, L. Q.; Ge, X. S.; Du, Y. N.; Qian, J. J.; Tang, G. D.; Zhong, W.

    2018-06-01

    X-ray photoelectron spectra of the O 1s electrons of MnFe2O4, ZnFe2O4, ZnO, and CaO were used to estimate the average valence, ValO, of the oxygen anions in these samples. The absolute values of ValO for these samples were found to be distinctly lower than the traditional value of 2.0, suggesting that the total average valences of the cations are also lower than the conventionally accepted values owing to valence balance in the compounds. In addition, we analyzed the valence band spectra of the samples and investigated the distribution characteristics of the valence electrons.

  16. CREMA-D: Crowd-sourced Emotional Multimodal Actors Dataset

    PubMed Central

    Cao, Houwei; Cooper, David G.; Keutmann, Michael K.; Gur, Ruben C.; Nenkova, Ani; Verma, Ragini

    2014-01-01

    People convey their emotional state in their face and voice. We present an audio-visual data set uniquely suited for the study of multi-modal emotion expression and perception. The data set consists of facial and vocal emotional expressions in sentences spoken in a range of basic emotional states (happy, sad, anger, fear, disgust, and neutral). 7,442 clips of 91 actors with diverse ethnic backgrounds were rated by multiple raters in three modalities: audio, visual, and audio-visual. Categorical emotion labels and real-value intensity values for the perceived emotion were collected using crowd-sourcing from 2,443 raters. The human recognition of intended emotion for the audio-only, visual-only, and audio-visual data are 40.9%, 58.2% and 63.6% respectively. Recognition rates are highest for neutral, followed by happy, anger, disgust, fear, and sad. Average intensity levels of emotion are rated highest for visual-only perception. The accurate recognition of disgust and fear requires simultaneous audio-visual cues, while anger and happiness can be well recognized based on evidence from a single modality. The large dataset we introduce can be used to probe other questions concerning the audio-visual perception of emotion. PMID:25653738

  17. Myocardial Performance Index for Patients with Overt and Subclinical Hypothyroidism.

    PubMed

    Karabulut, Aziz; Doğan, Abdullah; Tuzcu, Alpaslan Kemal

    2017-05-25

    BACKGROUND Hypothyroid has several effects on the cardiovascular system. Global myocardial performance index (MPI) is used in assessment of both left ventricular (LV) systolic and diastolic function. We compared MPI in hypothyroidism patients vs. normal control subjects. MATERIAL AND METHODS Eighty-two hypothyroid patients were divided into 2 groups: a subclinical hypothyroid (SH) group (n=50), and an overt hypothyroid (OH) group (n=32). The healthy control group (CG) constituted of 37 patients. TSH, FT3, and FT4, anti-TPO, anti-TG, insulin, lipid values, and fasting glucose levels were studied. All patients underwent an echocardiographic examination. Myocardial performance indexes were assessed and standard echocardiographic examinations were investigated. RESULTS MPI averages in OH, SH, and control groups were 0.53±0.06, 0.51±0.05, and 0.44±0.75 mm, respectively. MPI was increased in the OH and SH groups in comparison to CG (p<0.001, p<0.001, respectively). CONCLUSIONS MPI value was significantly higher in hypothyroid patients in comparison to the control group, showing that regression in global left ventricular functions is an important echocardiographic finding. Future studies are required to determine the effects of this finding on long-term cardiovascular outcomes.

  18. Oscillatory attractors: a new cosmological phase

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bains, Jasdeep S.; Hertzberg, Mark P.; Wilczek, Frank, E-mail: bains@physics.harvard.edu, E-mail: mark.hertzberg@tufts.edu, E-mail: wilczek@mit.edu

    2017-05-01

    In expanding FRW spacetimes, it is usually the case that homogeneous scalar fields redshift and their amplitudes approach limiting values: Hubble friction usually ensures that the field relaxes to its minimum energy configuration, which is usually a static configuration. Here we discover a class of relativistic scalar field models in which the attractor behavior is the field oscillating indefinitely, with finite amplitude, in an expanding FRW spacetime, despite the presence of Hubble friction. This is an example of spontaneous breaking of time translation symmetry. We find that the effective equation of state of the field has average value ( wmore » )=−1, implying that the field itself could drive an inflationary or dark energy dominated phase. This behavior is reminiscent of ghost condensate models, but in the new models, unlike in the ghost condensate models, the energy-momentum tensor is time dependent, so that these new models embody a more definitive breaking of time translation symmetry. We explore (quantum) fluctuations around the homogeneous background solution, and find that low k -modes can be stable, while high k -modes are typically unstable. We discuss possible interpretations and implications of that instability.« less

  19. Qualities of adolescent mothers' parenting.

    PubMed

    East, P L; Matthews, K L; Felice, M E

    1994-03-01

    This study examined the interrelations among adolescent mothers' parenting attitudes, parenting confidence, and parenting stress and the potential differences in these dimensions by mothers' age, race and parity, and age and sex of child. Subjects were 119 former adolescent mothers (M age = 20.2 years) from predominantly poor, minority backgrounds (50% Hispanic, 27% African-American, 17% non-Hispanic white). All subjects completed questionnaires about their parenting qualities twice an average of 10 weeks apart. All children were at least one year of age (M age = 37.2 months; range 12-50 months). Results indicated that for some mothers there exists a triple jeopardy of low parenting confidence, high parenting stress, and inappropriate parenting values. Young maternal age at delivery and young maternal age at the time of this study were associated with low child acceptance. Non-Hispanic white mothers had significantly more favorable parenting values than did African-American and Hispanic mothers, and African-American mothers reported significantly greater caretaking confidence than did Hispanic mothers. No parity or sex of child effects were found. These results suggest the presence of meaningful patterns of convergence and within-group variation for the psychological qualities of adolescent mothers' parenting.

  20. Identification of Heavy Metal Pollution Derived From Traffic in Roadside Soil Using Magnetic Susceptibility.

    PubMed

    Yang, Pingguo; Ge, Jing; Yang, Miao

    2017-06-01

    The study integrates surface and vertical distribution of magnetic susceptibility and heavy metal contents (Pb, Cu, Zn and Fe) to characterize the signature of vehicle pollutants in roadside soils at Linfen city, China. Sites with reforestation and without vegetation cover were investigated. The results showed that magnetic susceptibility and heavy metal contents were higher at the roadside without trees than in the reforest belt. The variations of magnetic susceptibility and heavy metal contents decreased both with distance and with depth. The maximum value was observed at 5-10 m away from the roadside edge. The vertical distribution in soil revealed accumulation of pollutants in 0-5 cm topsoils. The average contents were higher than the background values and in the order Fe (107.21 g kg -1 ), Zn (99.72 mg kg -1 ), Pb (90.99 mg kg -1 ), Cu (36.14 mg kg -1 ). Coarse multi domain grains were identified as the dominating magnetic particles. Multivariate statistical and SEM/EDX analyses suggested that the heavy metals derived from traffic sources. Trees act as efficient receptors and green barrier, which can reduce vehicle derived pollution.

  1. NATURAL RADIOACTIVITY LEVEL AND ELEMENTAL COMPOSITION OF SOIL SAMPLES FROM A HIGH BACKGROUND RADIATION AREA ON EASTERN COAST OF INDIA (ODISHA).

    PubMed

    Sahoo, S K; Kierepko, R; Sorimachi, A; Omori, Y; Ishikawa, T; Tokonami, S; Prasad, G; Gusain, G S; Ramola, R C

    2016-10-01

    A comprehensive study was carried out to determine the radioactivity concentration of soil samples from different sites of a high background radiation area in the eastern coast of India, Odisha state. The dose rate measured in situ varied from 0.25 to 1.2 µSv h -1 The gamma spectrometry measurements indicated Th series elements as the main contributors to the enhanced level of radiation and allowed the authors to find the mean level of the activity concentration (±SD) for 226 Ra, 228 Th and 40 K as 130±97, 1110±890 and 360±140 Bq kg -1 , respectively. Human exposure from radionuclides occurring outdoor was estimated based on the effective dose rate, which ranged from 0.14±0.02 to 2.15±0.26 mSv and was higher than the UNSCEAR annual worldwide average value 0.07 mSv. Additionally, X-ray fluorescence analysis provided information about the content of major elements in samples and indicated the significant amount of Ti (7.4±4.9 %) in soils. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Eyjafjallajokull Volcano Plume Particle-Type Characterization from Space-Based Multi-angle Imaging

    NASA Technical Reports Server (NTRS)

    Kahn, Ralph A.; Limbacher, James

    2012-01-01

    The Multi-angle Imaging SpectroRadiometer (MISR) Research Aerosol algorithm makes it possible to study individual aerosol plumes in considerable detail. From the MISR data for two optically thick, near-source plumes from the spring 2010 eruption of the Eyjafjallaj kull volcano, we map aerosol optical depth (AOD) gradients and changing aerosol particle types with this algorithm; several days downwind, we identify the occurrence of volcanic ash particles and retrieve AOD, demonstrating the extent and the limits of ash detection and mapping capability with the multi-angle, multi-spectral imaging data. Retrieved volcanic plume AOD and particle microphysical properties are distinct from background values near-source, as well as for overwater cases several days downwind. The results also provide some indication that as they evolve, plume particles brighten, and average particle size decreases. Such detailed mapping offers context for suborbital plume observations having much more limited sampling. The MISR Standard aerosol product identified similar trends in plume properties as the Research algorithm, though with much smaller differences compared to background, and it does not resolve plume structure. Better optical analogs of non-spherical volcanic ash, and coincident suborbital data to validate the satellite retrieval results, are the factors most important for further advancing the remote sensing of volcanic ash plumes from space.

  3. [Study on the content and carbon isotopic composition of water dissolved inorganic carbon from rivers around Xi'an City].

    PubMed

    Guo, Wei; Li, Xiang-Zhong; Liu, Wei-Guo

    2013-04-01

    In this study, the content and isotopic compositions of water dissolved inorganic carbon (DIC) from four typical rivers (Chanhe, Bahe, Laohe and Heihe) around Xi'an City were studied to trace the possible sources of DIC. The results of this study showed that the content of DIC in the four rivers varied from 0.34 to 5.66 mmol x L(-1) with an average value of 1.23 mmol x L(-1). In general, the content of DIC increased from the headstream to the river mouth. The delta13C(DIC) of four rivers ranged from -13.3 per thousand to -7.2 per thousand, with an average value of -10.1 per thousand. The delta13C(DIC) values of river water were all negative (average value of -12.6 per thousand) at the headstream of four rivers, but the delta13C(DIC) values of downstream water were more positive (with an average value of -9.4 per thousand). In addition, delta13C(DIC) of river water showed relatively negative values (the average value of delta13C(DIC) was -10.5 per thousand) near the estuary of the rivers. The variation of the DIC content and its carbon isotope suggested that the DIC sources of the rivers varied from the headstream to the river mouth. The negative delta13C(DIC) value indicated that the DIC may originate from the soil CO2 at the headstream of the rivers. On the other hand, the delta13C(DIC) values of river water at the middle and lower reaches of rivers were more positive, and it showed that soil CO2 produced by respiration of the C4 plants (like corn) and soil carbonates with positive delta13C values may be imported into river water. Meanwhile, the input of pollutants with low delta13C(DIC) values may result in a decrease of delta13C(DIC) values in the rivers. The study indicated that the DIC content and carbon isotope may be used to trace the sources of DIC in rivers around Xi'an City. Our study may provide some basic information for tracing the sources of DIC of rivers in the small watershed area in the Loess Plateau of China.

  4. Langmuir probe measurements in a time-fluctuating-highly ionized non-equilibrium cutting arc: analysis of the electron retarding part of the time-averaged current-voltage characteristic of the probe.

    PubMed

    Prevosto, L; Kelly, H; Mancinelli, B

    2013-12-01

    This work describes the application of Langmuir probe diagnostics to the measurement of the electron temperature in a time-fluctuating-highly ionized, non-equilibrium cutting arc. The electron retarding part of the time-averaged current-voltage characteristic of the probe was analysed, assuming that the standard exponential expression describing the electron current to the probe in collision-free plasmas can be applied under the investigated conditions. A procedure is described which allows the determination of the errors introduced in time-averaged probe data due to small-amplitude plasma fluctuations. It was found that the experimental points can be gathered into two well defined groups allowing defining two quite different averaged electron temperature values. In the low-current region the averaged characteristic was not significantly disturbed by the fluctuations and can reliably be used to obtain the actual value of the averaged electron temperature. In particular, an averaged electron temperature of 0.98 ± 0.07 eV (= 11400 ± 800 K) was found for the central core of the arc (30 A) at 3.5 mm downstream from the nozzle exit. This average included not only a time-average over the time fluctuations but also a spatial-average along the probe collecting length. The fitting of the high-current region of the characteristic using such electron temperature value together with the corrections given by the fluctuation analysis showed a relevant departure of local thermal equilibrium in the arc core.

  5. Deviation Value for Conventional X-ray in Hospitals in South Sulawesi Province from 2014 to 2016

    NASA Astrophysics Data System (ADS)

    Bachtiar, Ilham; Abdullah, Bualkar; Tahir, Dahlan

    2018-03-01

    This paper describes the conventional X-ray machine parameters tested in the region of South Sulawesi from 2014 to 2016. The objective of this research is to know deviation of every parameter of conventional X-ray machine. The testing parameters were analyzed by using quantitative methods with participatory observational approach. Data collection was performed by testing the output of conventional X-ray plane using non-invasive x-ray multimeter. The test parameters include tube voltage (kV) accuracy, radiation output linearity, reproducibility and radiation beam value (HVL) quality. The results of the analysis show four conventional X-ray test parameters have varying deviation spans, where the tube voltage (kV) accuracy has an average value of 4.12%, the average radiation output linearity is 4.47% of the average reproducibility of 0.62% and the averaged of the radiation beam (HVL) is 3.00 mm.

  6. Method for detection and correction of errors in speech pitch period estimates

    NASA Technical Reports Server (NTRS)

    Bhaskar, Udaya (Inventor)

    1989-01-01

    A method of detecting and correcting received values of a pitch period estimate of a speech signal for use in a speech coder or the like. An average is calculated of the nonzero values of received pitch period estimate since the previous reset. If a current pitch period estimate is within a range of 0.75 to 1.25 times the average, it is assumed correct, while if not, a correction process is carried out. If correction is required successively for more than a preset number of times, which will most likely occur when the speaker changes, the average is discarded and a new average calculated.

  7. 49 CFR 537.9 - Determination of fuel economy values and average fuel economy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Determination of fuel economy values and average fuel economy. 537.9 Section 537.9 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AUTOMOTIVE FUEL ECONOMY REPORTS § 537.9 Determination of fuel...

  8. Comparing the Value of Nonprofit Hospitals’ Tax Exemption to Their Community Benefits

    PubMed Central

    Herring, Bradley; Gaskin, Darrell; Zare, Hossein; Anderson, Gerard

    2018-01-01

    The tax-exempt status of nonprofit hospitals has received increased attention from policymakers interested in examining the value they provide instead of paying taxes. We use 2012 data from the Internal Revenue Service (IRS) Form 990, Centers for Medicare and Medicaid Services (CMS) Hospital Cost Reports, and American Hospital Association’s (AHA) Annual Survey to compare the value of community benefits with the tax exemption. We contrast nonprofit’s total community benefits to what for-profits provide and distinguish between charity and other community benefits. We find that the value of the tax exemption averages 5.9% of total expenses, while total community benefits average 7.6% of expenses, incremental nonprofit community benefits beyond those provided by for-profits average 5.7% of expenses, and incremental charity alone average 1.7% of expenses. The incremental community benefit exceeds the tax exemption for only 62% of nonprofits. Policymakers should be aware that the tax exemption is a rather blunt instrument, with many nonprofits benefiting greatly from it while providing relatively few community benefits. PMID:29436247

  9. Geomagnetism during solar cycle 23: Characteristics.

    PubMed

    Zerbo, Jean-Louis; Amory-Mazaudier, Christine; Ouattara, Frédéric

    2013-05-01

    On the basis of more than 48 years of morphological analysis of yearly and monthly values of the sunspot number, the aa index, the solar wind speed and interplanetary magnetic field, we point out the particularities of geomagnetic activity during the period 1996-2009. We especially investigate the last cycle 23 and the long minimum which followed it. During this period, the lowest values of the yearly averaged IMF (3 nT) and yearly averaged solar wind speed (364 km/s) are recorded in 1996, and 2009 respectively. The year 2003 shows itself particular by recording the highest value of the averaged solar wind (568 km/s), associated to the highest value of the yearly averaged aa index (37 nT). We also find that observations during the year 2003 seem to be related to several coronal holes which are known to generate high-speed wind stream. From the long time (more than one century) study of solar variability, the present period is similar to the beginning of twentieth century. We especially present the morphological features of solar cycle 23 which is followed by a deep solar minimum.

  10. Improvement of the diagnostic accuracy of MRA with subtraction technique in cerebral vasospasm.

    PubMed

    Hamaguchi, Akiyoshi; Fujima, Noriyuki; Yoshida, Daisuke; Hamaguchi, Naoko; Kodera, Shuichi

    2014-01-01

    Vasospasm has been considered the most severe acute complication after subarachnoid hemorrhage (SAH). MRA is not considered ideal for detecting cerebral vasospasm because of background including the hemorrhage. The aim of this study is to evaluate the efficacy of Subtraction MRA (SMRA) by comparing it to that of conventional MRA (CMRA) for diagnosis of cerebral vasospasm. Arteries were assigned to one of three categories based on the degree of MRA diagnostic quality of vasospasm (quality score): 0, bad … 2, good. Furthermore each artery was assigned to one of four categories based on the degree of vasospasm severity (SV score): 0, no vasospasm … 3, severe. The value of the difference between DSA-SV score and MRA-SV score was defined as the DIF score. CMRA and SMRA were compared for each arterial region with regard to quality score and DIF score. The average CMRA and SMRA quality score were 1.46 and 1.79; the difference was statistically significant. The average CMRA and SMRA DIF score were 1.08 and .60; the difference was statistically significant. Diagnosis of cerebral vasospasm is more accurate by SMRA than by CMRA. The advantages are its noninvasive nature and its ability to detect cerebral vasospasm. Copyright © 2014 by the American Society of Neuroimaging.

  11. Spatial distribution and source identification of heavy metals in surface soils in a typical coal mine city, Lianyuan, China.

    PubMed

    Liang, Jie; Feng, Chunting; Zeng, Guangming; Gao, Xiang; Zhong, Minzhou; Li, Xiaodong; Li, Xin; He, Xinyue; Fang, Yilong

    2017-06-01

    In this study, we investigated the pollution degree and spatial distribution of heavy metals and determined their sources in topsoil in a typical coal mine city, Lianyuan, Hunan Province, China. We collected 6078 soil surface samples in different land use types. And the concentrations of Zn, Cd, Cu, Hg, Pb, Sb, As, Mo, V, Mn, Fe and Cr were measured. The average contents of all heavy metals were lower than their corresponding Grade II values of Chinese Soil Quality Standard with the exception of Hg. However, average contents of twelve heavy metals, except for Mn, exceeded their background level in soils in Hunan Province. Based on one-way analysis of variance (ANOVA), the contents of Cu, Zn, Cd, Pb, Hg, Mo and V were related to the anthropogenic source and there were statistically significant differences in their concentrations among different land use patterns. The spatial variation of heavy metal was visualized by GIS. The PMF model was used to ascertain contamination sources of twelve heavy metals and apportion their source contributions in Lianyuan soils. The results showed that the source contributions of the natural source, atmospheric deposition, industrial activities and agricultural activities accounted for 33.6%, 26.05%, 23.44% and 16.91%, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. A Study of the Relationship Between Nurses’ Professional Self-Concept and Professional Ethics in Hospitals Affiliated to Jahrom University of Medical Sciences, Iran

    PubMed Central

    Parandavar, Nehleh; Rahmanian, Afifeh; Jahromi, Zohreh Badiyepeymaie

    2016-01-01

    Background: Commitment to ethics usually results in nurses’ better professional performance and advancement. Professional self-concept of nurses refers to their information and beliefs about their roles, values, and behaviors. The objective of this study is to analyze the relationship between nurses’ professional self-concept and professional ethics in hospitals affiliated to Jahrom University of Medical Sciences. Methods: This cross sectional-analytical study was conducted in 2014. The 270 participants were practicing nurses and head-nurses at the teaching hospitals of Peimanieh and Motahari in Jahrom University of Medical Science. Sampling was based on sencus method. Data was collected using Cowin's Nurses’ self-concept questionnaire (NSCQ) and the researcher-made questionnaire of professional ethics. Results: The average of the sample's professional self-concept score was 6.48±0.03 out of 8. The average of the sample's commitment to professional ethics score was 4.08±0.08 out of 5. Based on Pearson's correlation test, there is a significant relationship between professional ethics and professional self-concept (P=0.01, r=0.16). Conclusion: In view of the correlation between professional self-concept and professional ethics, it is recommended that nurses’ self-concept, which can boost their commitment to ethics, be given more consideration. PMID:26573035

  13. A potential vorticity-based determination of the transport barrier in the Asian summer monsoon anticyclone

    NASA Astrophysics Data System (ADS)

    Ploeger, F.; Gottschling, C.; Griessbach, S.; Grooß, J.-U.; Guenther, G.; Konopka, P.; Müller, R.; Riese, M.; Stroh, F.; Tao, M.; Ungermann, J.; Vogel, B.; von Hobe, M.

    2015-11-01

    The Asian summer monsoon provides an important pathway of tropospheric source gases and pollution into the lower stratosphere. This transport is characterized by deep convection and steady upwelling, combined with confinement inside a large-scale anticyclonic circulation in the upper troposphere and lower stratosphere (UTLS). In this paper, we show that a barrier to horizontal transport along the 380 K isentrope in the monsoon anticyclone can be determined from a local maximum in the gradient of potential vorticity (PV), following methods developed for the polar vortex (e.g., Nash et al., 1996). The monsoon anticyclone is dynamically highly variable and the maximum in the PV gradient is weak, such that additional constraints are needed (e.g., time averaging). Nevertheless, PV contours in the monsoon anticyclone agree well with contours of trace gas mixing ratios (CO, O3) and mean age from model simulations with a Lagrangian chemistry transport model (CLaMS) and satellite observations from the Microwave Limb Sounder (MLS) instrument. Hence, the PV-based transport barrier reflects the separation between air inside the core of the anticyclone and the background atmosphere well. For the summer season 2011 we find an average PV value of 3.6 PVU for the transport barrier in the anticyclone on the 380 K isentrope.

  14. Pepsin and Bile Acid Concentrations in Sputum of Mustard Gas Exposed Patients

    PubMed Central

    Karbasi, Ashraf; Goosheh, Hassan; Aliannejad, Rasoul; Saber, Hamid; Salehi, Maryam; Jafari, Mahvash; Imani, Saber; Saburi, Amin; Ghanei, Mostafa

    2013-01-01

    Background/Aim: Gastro-esophageal reflux has been suggested to be associated with several pulmonary complications such as asthma, and post-transplant bronchiolitis obliterans (BO). Pepsin or bile salts in the sputum is shown to be an optimal molecular marker of gastric contents macro/micro aspiration. In this study, we investigated sputum pepsin as a marker of micro-aspiration in sulfur mustard (SM) exposed cases compared to healthy controls. Materials and Methods: In a case controlled study, 26 cases with BO and 12 matched healthy controls were recruited and all cases were symptomatic and their exposure to SM was previously documented during Iran-Iraq conflict. Pepsin levels in sputum and total bile acids were measured using enzymatic assay. The severity of respiratory disorder was categorized based upon the spirometric values. Result: The average concentration of pepsin in sputum was higher in the case group (0.29 ± 0.23) compared with healthy subjects (0.13 ± 0.07; P ± 0.003). Moreover, the average concentration of bile acids in the sputum cases was not significantly different in comparison to the controls (P = 0.5). Conclusion: Higher pepsin concentrations in sputum of SM exposed patients compared with healthy control subjects indicate the occurrence of significantly more gastric micro-aspiration in SM exposed patients. PMID:23680709

  15. The spatial distribution, accumulation and potential source of seldom monitored trace elements in sediments of Three Gorges Reservoir, China

    PubMed Central

    Han, Lanfang; Gao, Bo; Zhou, Huaidong; Xu, Dongyu; Wei, Xin; Gao, Li

    2015-01-01

    The alteration of hydrologic condition of Three Gorges Reservoir (TGR) after impoundment has caused numerous environmental changes. This study investigated the distribution, accumulation and potential sources of the seldom monitored trace elements (SMTEs) in sediments from three tributaries (ZY, MX and CT) and one mainstream (CJ) in TGR during different seasons. The average contents of most SMTEs excluding Sb in the winter were similar to that in the summer. For Sb, its average concentrations in the summer and winter were roughly six and three times higher than its background value, respectively. Contamination factor (CF) and geoaccumulation index (Igeo) demonstrated that most of the sediments were obviously contaminated by Sb. The enrichment factors (EF) of Ga and Sb were higher than 2.0, revealing the possible anthropogenic inputs; However, the EFs of other SMTEs were lower than 1.5, indicating the natural inputs. Correlation and principal component analysis suggested the most SMTEs were positively correlated with major elements (Cr, Mn, Cu, Zn, As, Cd and Pb) and clay contents, which implies that SMTEs had the same sources with these major metals, and the fine particles might be a major carrier for transporting SMTEs from the rivers to the TGR. PMID:26538153

  16. Effect of slice thickness on brain magnetic resonance image texture analysis

    PubMed Central

    2010-01-01

    Background The accuracy of texture analysis in clinical evaluation of magnetic resonance images depends considerably on imaging arrangements and various image quality parameters. In this paper, we study the effect of slice thickness on brain tissue texture analysis using a statistical approach and classification of T1-weighted images of clinically confirmed multiple sclerosis patients. Methods We averaged the intensities of three consecutive 1-mm slices to simulate 3-mm slices. Two hundred sixty-four texture parameters were calculated for both the original and the averaged slices. Wilcoxon's signed ranks test was used to find differences between the regions of interest representing white matter and multiple sclerosis plaques. Linear and nonlinear discriminant analyses were applied with several separate training and test sets to determine the actual classification accuracy. Results Only moderate differences in distributions of the texture parameter value for 1-mm and simulated 3-mm-thick slices were found. Our study also showed that white matter areas are well separable from multiple sclerosis plaques even if the slice thickness differs between training and test sets. Conclusions Three-millimeter-thick magnetic resonance image slices acquired with a 1.5 T clinical magnetic resonance scanner seem to be sufficient for texture analysis of multiple sclerosis plaques and white matter tissue. PMID:20955567

  17. Brace related stress in scoliosis patients – Comparison of different concepts of bracing

    PubMed Central

    Weiss, Hans-Rudolf; Werkmann, Mario; Stephan, Carola

    2007-01-01

    Background The BSSQbrace questionnaire has been shown to be reliable with good internal consistency and reproducibility estimating the stress scoliosis patients have whilst wearing their brace. Eight questions are provided focussing on this topic. A max. score of 24 can be achieved (from 0 for most stress to 24 for no stress). The subdivision of the score values is: 0–8 (strong stress), 9–16 (medium stress) and 17–24 (little stress). Study design Two BSSQbrace questionnaires have been posted to 65 patients under brace treatment from our Cheneau light data base. All patients had another kind of brace prior to the Cheneau light. The patients have been asked to rate their stress level using one questionnaire for the current brace and the other for the previous one. Results 63 Patients (59 girls and 4 boys) returned their fully completed questionnaires (average age 13,6 years, average Cobb angle 43,7 degrees). Stress level in the previous brace was 11,04 and in the Cheneau light(r) 13,87. The differences were highly significant in the t-test; t = -4,67; p < 0,001. Conclusion The use of the Cheneau light® brace leads to reduced stress and/or impairment for the patients under treatment compared to heavier brace models used so far. PMID:17708766

  18. Bias of Tedlar bags in the measurement of agricultural odorants.

    PubMed

    Trabue, Steven L; Anhalt, Jennifer C; Zahn, James A

    2006-01-01

    Odor regulations typically specify the use of dynamic dilution olfactometery (DDO) as a method to quantify odor emissions, and Tedlar bags are the preferred holding container for grab samples. This study was conducted to determine if Tedlar bags affect the integrity of sampled air from animal operations. Air samples were collected simultaneously in both Tedlar bags and Tenax thermal desorption tubes. Sample sources originated from either a hydrocarbon-free air tank, dynamic headspace chamber (DHC), or swine-production facility, and were analyzed by gas chromatography-mass spectrometry-olfactometry (GC-MS-O). Several background contaminants were identified from Tedlar bags, which included the odorous compounds N,N-dimethyl acetamide (DMAC), acetic acid, and phenol. Samples from the DHC demonstrated that recovery of malodor compounds was dependent on residence time in the Tedlar bag with longer residence time leading to lower recovery. After 24 h of storage, recovery of C3-C6 volatile fatty acids (VFA) averaged 64%, 4-methylphenol and 4-ethylphenol averaged 10%, and indole and 3-methylindole were below the detection limits of GC-MS-O. The odor activity value (OAV) of grab samples collected in Tedlar bags were 33 to 65% lower following 24 h of storage. These results indicate that significant odorant bias occurs when using Tedlar bags for the sampling of odors from animal production facilities.

  19. Calculation of weighted averages approach for the estimation of ping tolerance values

    USGS Publications Warehouse

    Silalom, S.; Carter, J.L.; Chantaramongkol, P.

    2010-01-01

    A biotic index was created and proposed as a tool to assess water quality in the Upper Mae Ping sub-watersheds. The Ping biotic index was calculated by utilizing Ping tolerance values. This paper presents the calculation of Ping tolerance values of the collected macroinvertebrates. Ping tolerance values were estimated by a weighted averages approach based on the abundance of macroinvertebrates and six chemical constituents that include conductivity, dissolved oxygen, biochemical oxygen demand, ammonia nitrogen, nitrate nitrogen and orthophosphate. Ping tolerance values range from 0 to 10. Macroinvertebrates assigned a 0 are very sensitive to organic pollution while macroinvertebrates assigned 10 are highly tolerant to pollution.

  20. Evaluation of annual effective dose from indoor radon concentration in Eastern Province, Dammam, Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Abuelhia, E.

    2017-11-01

    The aim of this study is to determine the indoor radon concentration and to evaluate the annual effective dose received by the inhabitants in Dammam, Al-Khobar, and compare it with new premises built at university of dammam. The research has been carried out by using active detection method; Electronic Radon Detector (RAD-7) a solid state α-detector with its special accessories. The indoor radon concentration measured varies from 10.2 Bqm-3 to 25.8 Bqm-3 with an average value of 18.8 Bqm-3 and 19.7 Bqm-3 to 23.5 Bqm-3 with an average value of 21.7 Bqm-3, in Dammam and Al-khobar dwellings, respectively. In university of dammam the radon concentration varies from 7.4 Bqm-3 to 15.8 Bqm-3 with an average value of 9.02 Bqm-3. The values of annual effective doses were found to be 0.47mSv/y, 0.55mSv/y, and 0.23mSv/y, in Dammam, Al-khobar and university new premises, respectively. The average radon concentration in the old dwellings was two times compared to that in the new premises and it was 25.4 Bqm-3 lower than the world average value of 40 Bqm-3 reported by the UNSCEAR. The annual effective doses in the old dwellings was found to be (0.55mSv/y) two times the doses received at the new premises, and below the world wide average of 1.15mSv/y reported by ICRP (2010). The indoor radon concentration in the study region is safe as far as health hazard is concerned.

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