Sample records for average intermarker distance

  1. A new method to quantify liner deformation within a prosthetic socket for below knee amputees.

    PubMed

    Lenz, Amy L; Johnson, Katie A; Bush, Tamara Reid

    2018-06-06

    Many amputees who wear a leg prosthesis develop significant skin wounds on their residual limb. The exact cause of these wounds is unclear as little work has studied the interface between the prosthetic device and user. Our research objective was to develop a quantitative method for assessing displacement patterns of the gel liner during walking for patients with transtibial amputation. Using a reflective marker system and a custom clear socket, evaluations were conducted with a clear transparent test socket mounted over a plaster limb model and a deformable limb model. Distances between markers placed on the limb were measured with a digital caliper and then compared with data from the motion capture system. Additionally, the rigid plaster set-up was moved in the capture volume to simulate walking and evaluate if inter-marker distances changed in comparison to static data. Dynamic displacement trials were then collected to measure changes in inter-marker distance due to vertical elongation of the gel liner. Static and dynamic inter-marker distances within day and across days confirmed the ability to accurately capture displacements using this new approach. These results encourage this novel method to be applied to a sample of amputee patients during walking to assess displacements and the distribution of the liner deformation within the socket. The ability to capture changes in deformation of the gel liner will provide new data that will enable clinicians and researchers to improve design and fit of the prosthesis so the incidence of pressure ulcers can be reduced. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. A microsatellite genetic linkage map of black rockfish ( Sebastes schlegeli)

    NASA Astrophysics Data System (ADS)

    Chu, Guannan; Jiang, Liming; He, Yan; Yu, Haiyang; Wang, Zhigang; Jiang, Haibin; Zhang, Quanqi

    2014-12-01

    Ovoviviparous black rockfish ( Sebastes schlegeli) is an important marine fish species for aquaculture and fisheries in China. Genetic information of this species is scarce because of the lack of microsatellite markers. In this study, a large number of microsatellite markers of black rockfish were isolated by constructing microsatellite-enriched libraries. Female- and male-specific genetic linkage maps were constructed using 435 microsatellite markers genotyped in a full-sib family of the fish species. The female linkage map contained 140 microsatellite markers, in which 23 linkage groups had a total genetic length of 1334.1 cM and average inter-marker space of 13.3 cM. The male linkage map contained 156 microsatellite markers, in which 25 linkage groups had a total genetic length of 1359.6 cM and average inter-marker distance of 12.4 cM. The genome coverage of the female and male linkage maps was 68.6% and 69.3%, respectively. The female-to-male ratio of the recombination rate was approximately 1.07:1 in adjacent microsatellite markers. This paper presents the first genetic linkage map of microsatellites in black rockfish. The collection of polymorphic markers and sex-specific linkage maps of black rockfish could be useful for further investigations on parental assignment, population genetics, quantitative trait loci mapping, and marker-assisted selection in related breeding programs.

  3. Extended Intermarker Linkage Disequilibrium in the Afrikaners

    PubMed Central

    Hall, Diana; Wijsman, Ellen M.; Roos, J. Louw; Gogos, Joseph A.; Karayiorgou, Maria

    2002-01-01

    In this study we conducted an investigation of the background level of linkage disequilibrium (LD) in the Afrikaner population to evaluate the appropriateness of this genetic isolate for mapping complex traits. We analyzed intermarker LD in 62 nuclear families using microsatellite markers covering extended chromosomal regions. The markers were selected to allow the first direct comparison of long-range LD in the Afrikaners to LD in other demographic groups. Using several statistical measures, we find significant evidence for LD in the Afrikaners extending remarkably over a 6-cM range. In contrast, LD decays significantly beyond 3-cM distances in the other founder and outbred populations examined. This study strongly supports the appropriateness of the Afrikaner population for genome-wide scans that exploit LD to map common, multigenic disorders. PMID:12045148

  4. Extended intermarker linkage disequilibrium in the Afrikaners.

    PubMed

    Hall, Diana; Wijsman, Ellen M; Roos, J Louw; Gogos, Joseph A; Karayiorgou, Maria

    2002-06-01

    In this study we conducted an investigation of the background level of linkage disequilibrium (LD) in the Afrikaner population to evaluate the appropriateness of this genetic isolate for mapping complex traits. We analyzed intermarker LD in 62 nuclear families using microsatellite markers covering extended chromosomal regions. The markers were selected to allow the first direct comparison of long-range LD in the Afrikaners to LD in other demographic groups. Using several statistical measures, we find significant evidence for LD in the Afrikaners extending remarkably over a 6-cM range. In contrast, LD decays significantly beyond 3-cM distances in the other founder and outbred populations examined. This study strongly supports the appropriateness of the Afrikaner population for genome-wide scans that exploit LD to map common, multigenic disorders.

  5. Extent of Linkage Disequilibrium and Effective Population Size in Four South African Sanga Cattle Breeds.

    PubMed

    Makina, Sithembile O; Taylor, Jeremy F; van Marle-Köster, Este; Muchadeyi, Farai C; Makgahlela, Mahlako L; MacNeil, Michael D; Maiwashe, Azwihangwisi

    2015-01-01

    Knowledge on the extent of linkage disequilibrium (LD) in livestock populations is essential to determine the minimum distance between markers required for effective coverage when conducting genome-wide association studies (GWAS). This study evaluated the extent of LD, persistence of allelic phase and effective population size (Ne) for four Sanga cattle breeds in South Africa including the Afrikaner (n = 44), Nguni (n = 54), Drakensberger (n = 47), and Bonsmara breeds (n = 46), using Angus (n = 31) and Holstein (n = 29) as reference populations. We found that moderate LD extends up to inter-marker distances of 40-60 kb in Angus (0.21) and Holstein (0.21) and up to 100 kb in Afrikaner (0.20). This suggests that genomic selection and association studies performed within these breeds using an average inter-marker r (2)≥ 0.20 would require about 30,000-50,000 SNPs. However, r (2)≥ 0.20 extended only up to 10-20 kb in the Nguni and Drakensberger and 20-40 kb in the Bonsmara indicating that 75,000 to 150,000 SNPs would be necessary for GWAS in these breeds. Correlation between alleles at contiguous loci indicated that phase was not strongly preserved between breeds. This suggests the need for breed-specific reference populations in which a much greater density of markers should be scored to identify breed specific haplotypes which may then be imputed into multi-breed commercial populations. Analysis of effective population size based on the extent of LD, revealed Ne = 95 (Nguni), Ne = 87 (Drakensberger), Ne = 77 (Bonsmara), and Ne = 41 (Afrikaner). Results of this study form the basis for implementation of genomic selection programs in the Sanga breeds of South Africa.

  6. Extent of Linkage Disequilibrium and Effective Population Size in Four South African Sanga Cattle Breeds

    PubMed Central

    Makina, Sithembile O.; Taylor, Jeremy F.; van Marle-Köster, Este; Muchadeyi, Farai C.; Makgahlela, Mahlako L.; MacNeil, Michael D.; Maiwashe, Azwihangwisi

    2015-01-01

    Knowledge on the extent of linkage disequilibrium (LD) in livestock populations is essential to determine the minimum distance between markers required for effective coverage when conducting genome-wide association studies (GWAS). This study evaluated the extent of LD, persistence of allelic phase and effective population size (Ne) for four Sanga cattle breeds in South Africa including the Afrikaner (n = 44), Nguni (n = 54), Drakensberger (n = 47), and Bonsmara breeds (n = 46), using Angus (n = 31) and Holstein (n = 29) as reference populations. We found that moderate LD extends up to inter-marker distances of 40–60 kb in Angus (0.21) and Holstein (0.21) and up to 100 kb in Afrikaner (0.20). This suggests that genomic selection and association studies performed within these breeds using an average inter-marker r2≥ 0.20 would require about 30,000–50,000 SNPs. However, r2≥ 0.20 extended only up to 10–20 kb in the Nguni and Drakensberger and 20–40 kb in the Bonsmara indicating that 75,000 to 150,000 SNPs would be necessary for GWAS in these breeds. Correlation between alleles at contiguous loci indicated that phase was not strongly preserved between breeds. This suggests the need for breed-specific reference populations in which a much greater density of markers should be scored to identify breed specific haplotypes which may then be imputed into multi-breed commercial populations. Analysis of effective population size based on the extent of LD, revealed Ne = 95 (Nguni), Ne = 87 (Drakensberger), Ne = 77 (Bonsmara), and Ne = 41 (Afrikaner). Results of this study form the basis for implementation of genomic selection programs in the Sanga breeds of South Africa. PMID:26648975

  7. Stability of Markers Used for Real-Time Tumor Tracking After Percutaneous Intrapulmonary Placement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voort van Zyp, Noelle C. van der, E-mail: n.vandervoortvanzyp@erasmusmc.nl; Hoogeman, Mischa S.; Water, Steven van de

    2011-11-01

    Purpose: To determine the stability of markers used for real-time tumor tracking after percutaneous intrapulmonary placement. Methods and Materials: A total of 42 patients with 44 lesions, 111 markers, and {>=}2 repeat computed tomography (CT) scans were studied. The tumor on the repeat CT scans was registered with the tumor on the planning CT scan. Next, the three-dimensional marker coordinates were determined on the planning CT scan and repeat CT scans. Marker stability was analyzed by the displacement of the markers and the displacement of the center of mass (COM) of the marker configurations. In addition, we assessed the reliabilitymore » of using the intermarker distance as a check for displacements in the COM of the marker configurations. Results: The median marker displacement was 1.3 mm (range, 0.1-53.6). The marker displacement was >5 mm in 12% of the markers and >10 mm in 5% of the markers. The causes of marker displacement >5 mm included marker migration (2 of 13) and target volume changes (5 of 13). Nonsynchronous tumor and marker movement during breathing might have been responsible for the displacements >5 mm in the other 6 of 13 markers. The median displacement in the COM of the marker configurations was 1.0 mm (range, 0.1-23.3). Displacements in the COM of the marker configurations of {>=}2.0 mm were detected by changes in the intermarker distance of >1.5 mm in 96% of the treatment fractions. Conclusion: The median marker displacement was small (1.3 mm). Nevertheless, displacements >5 mm occurred in 12% of the markers. Therefore, we recommend the implantation of multiple markers because multiple markers will enable a quick and reliable check of marker displacement by determining the change in the intermarker distance. A displacement in the COM of the marker configuration of {>=}2.0 mm was almost always detected (96%) by a change in the distance between the markers of >1.5 mm. This enabled the displaced marker to be disabled, such that tumor localization was not compromised.« less

  8. A gene-based SNP resource and linkage map for the copepod Tigriopus californicus

    PubMed Central

    2011-01-01

    Background As yet, few genomic resources have been developed in crustaceans. This lack is particularly evident in Copepoda, given the extraordinary numerical abundance, and taxonomic and ecological diversity of this group. Tigriopus californicus is ideally suited to serve as a genetic model copepod and has been the subject of extensive work in environmental stress and reproductive isolation. Accordingly, we set out to develop a broadly-useful panel of genetic markers and to construct a linkage map dense enough for quantitative trait locus detection in an interval mapping framework for T. californicus--a first for copepods. Results One hundred and ninety Single Nucleotide Polymorphisms (SNPs) were used to genotype our mapping population of 250 F2 larvae. We were able to construct a linkage map with an average intermarker distance of 1.8 cM, and a maximum intermarker distance of 10.3 cM. All markers were assembled into linkage groups, and the 12 linkage groups corresponded to the 12 known chromosomes of T. californicus. We estimate a total genome size of 401.0 cM, and a total coverage of 73.7%. Seventy five percent of the mapped markers were detected in 9 additional populations of T. californicus. Of available model arthropod genomes, we were able to show more colocalized pairs of homologues between T. californicus and the honeybee Apis mellifera, than expected by chance, suggesting preserved macrosynteny between Hymenoptera and Copepoda. Conclusions Our study provides an abundance of linked markers spanning all chromosomes. Many of these markers are also found in multiple populations of T. californicus, and in two other species in the genus. The genomic resource we have developed will enable mapping throughout the geographical range of this species and in closely related species. This linkage map will facilitate genome sequencing, mapping and assembly in an ecologically and taxonomically interesting group for which genomic resources are currently under development. PMID:22103327

  9. Second generation genetic linkage map for the gilthead sea bream Sparus aurata L.

    PubMed

    Tsigenopoulos, Costas S; Louro, Bruno; Chatziplis, Dimitrios; Lagnel, Jacques; Vogiatzi, Emmanouella; Loukovitis, Dimitrios; Franch, Rafaella; Sarropoulou, Elena; Power, Deborah M; Patarnello, Tomaso; Mylonas, Constantinos C; Magoulas, Antonios; Bargelloni, Luca; Canario, Adelino; Kotoulas, Georgios

    2014-12-01

    An updated second linkage map was constructed for the gilthead sea bream, Sparus aurata L., a fish species of great economic importance for the Mediterranean aquaculture industry. In contrast to the first linkage map which mainly consisted of genomic microsatellites (SSRs), the new linkage map is highly enriched with SSRs found in Expressed Sequence Tags (EST-SSRs), which greatly facilitates comparative mapping with other teleosts. The new map consists of 321 genetic markers in 27 linkage groups (LGs): 232 genomic microsatellites, 85 EST-SSRs and 4 SNPs; of those, 13 markers were linked to LGs but were not ordered. Eleven markers (5 SSRs, 5 EST-SSRs and 1 SNP) are not assigned to any LG. The total length of the sex-averaged map is 1769.7cM, 42% longer than the previously published one, and the number of markers in each LG ranges from 2 to 30. The inter-marker distance varies from 0 to 75.6cM, with an average of 5.75cM. The male and female maps have a length of 1349.2 and 2172.1cM, respectively, and the average distance between markers is 4.38 and 7.05cM, respectively. Comparative mapping with the three-spined stickleback (Gasterosteus acuulatus) chromosomes and scaffolds showed conserved synteny with 132 S. aurata markers (42.9% of those mapped) having a hit on the stickleback genome. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae.

    PubMed

    Davis, Brian W; Raudsepp, Terje; Pearks Wilkerson, Alison J; Agarwala, Richa; Schäffer, Alejandro A; Houck, Marlys; Chowdhary, Bhanu P; Murphy, William J

    2009-04-01

    We describe the construction of a high-resolution radiation hybrid (RH) map of the domestic cat genome, which includes 2662 markers, translating to an estimated average intermarker distance of 939 kilobases (kb). Targeted marker selection utilized the recent feline 1.9x genome assembly, concentrating on regions of low marker density on feline autosomes and the X chromosome, in addition to regions flanking interspecies chromosomal breakpoints. Average gap (breakpoint) size between cat-human ordered conserved segments is less than 900 kb. The map was used for a fine-scale comparison of conserved syntenic blocks with the human and canine genomes. Corroborative fluorescence in situ hybridization (FISH) data were generated using 129 domestic cat BAC clones as probes, providing independent confirmation of the long-range correctness of the map. Cross-species hybridization of BAC probes on divergent felids from the genera Profelis (serval) and Panthera (snow leopard) provides further evidence for karyotypic conservation within felids, and demonstrates the utility of such probes for future studies of chromosome evolution within the cat family and in related carnivores. The integrated map constitutes a comprehensive framework for identifying genes controlling feline phenotypes of interest, and to aid in assembly of a higher coverage feline genome sequence.

  11. A High-Resolution Cat Radiation Hybrid and Integrated FISH Mapping Resource for Phylogenomic Studies across Felidae

    PubMed Central

    Davis, Brian W.; Raudsepp, Terje; Wilkerson, Alison J. Pearks; Agarwala, Richa; Schäffer, Alejandro A.; Houck, Marlys; Ryder, Oliver A.; Chowdhdary, Bhanu P.; Murphy, William J.

    2008-01-01

    We describe the construction of a high-resolution radiation hybrid (RH) map of the domestic cat genome, which includes 2,662 markers, translating to an estimated average intermarker distance of 939 kilobases (Kb). Targeted marker selection utilized the recent feline 1.9x genome assembly, concentrating on regions of low marker density on feline autosomes and the X chromosome, in addition to regions flanking interspecies chromosomal breakpoints. Average gap (breakpoint) size between cat-human ordered conserved segments is less than 900 Kb. The map was used for a fine-scale comparison of conserved syntenic blocks with the human and canine genomes. Corroborative fluorescence in situ hybridization (FISH) data were generated using 129 domestic cat BAC-clones as probes, providing independent confirmation of the long-range correctness of the map. Cross-species hybridization of BAC probes on divergent felids from the genera Profelis (serval) and Panthera (snow leopard) provides further evidence for karyotypic conservation within felids, and demonstrates the utility of such probes for future studies of chromosome evolution within the cat family and in related carnivores. The integrated map constitutes a comprehensive framework for identifying genes controlling feline phenotypes of interest, and to aid in assembly of a higher coverage feline genome sequence. PMID:18951970

  12. Using DNA origami nanorulers as traceable distance measurement standards and nanoscopic benchmark structures.

    PubMed

    Raab, Mario; Jusuk, Ija; Molle, Julia; Buhr, Egbert; Bodermann, Bernd; Bergmann, Detlef; Bosse, Harald; Tinnefeld, Philip

    2018-01-29

    In recent years, DNA origami nanorulers for superresolution (SR) fluorescence microscopy have been developed from fundamental proof-of-principle experiments to commercially available test structures. The self-assembled nanostructures allow placing a defined number of fluorescent dye molecules in defined geometries in the nanometer range. Besides the unprecedented control over matter on the nanoscale, robust DNA origami nanorulers are reproducibly obtained in high yields. The distances between their fluorescent marks can be easily analysed yielding intermark distance histograms from many identical structures. Thus, DNA origami nanorulers have become excellent reference and training structures for superresolution microscopy. In this work, we go one step further and develop a calibration process for the measured distances between the fluorescent marks on DNA origami nanorulers. The superresolution technique DNA-PAINT is used to achieve nanometrological traceability of nanoruler distances following the guide to the expression of uncertainty in measurement (GUM). We further show two examples how these nanorulers are used to evaluate the performance of TIRF microscopes that are capable of single-molecule localization microscopy (SMLM).

  13. Evaluation of Bovine High-Density SNP Genotyping Array in Indigenous Dairy Cattle Breeds.

    PubMed

    Dash, S; Singh, A; Bhatia, A K; Jayakumar, S; Sharma, A; Singh, S; Ganguly, I; Dixit, S P

    2018-04-03

    In total 52 samples of Sahiwal ( 19 ), Tharparkar ( 17 ), and Gir ( 16 ) were genotyped by using BovineHD SNP chip to analyze minor allele frequency (MAF), genetic diversity, and linkage disequilibrium among these cattle. The common SNPs of BovineHD and 54K SNP Chips were also extracted and evaluated for their performance. Only 40%-50% SNPs of these arrays was found informative for genetic analysis in these cattle breeds. The overall mean of MAF for SNPs of BovineHD SNPChip was 0.248 ± 0.006, 0.241 ± 0.007, and 0.242 ± 0.009 in Sahiwal, Tharparkar and Gir, respectively, while that for 54K SNPs was on lower side. The average Reynold's genetic distance between breeds ranged from 0.042 to 0.055 based on BovineHD Beadchip, and from 0.052 to 0.084 based on 54K SNP Chip. The estimates of genetic diversity based on HD and 54K chips were almost same and, hence, low density chip seems to be good enough to decipher genetic diversity of these cattle breeds. The linkage disequilibrium started decaying (r 2  < 0.2) at 140 kb inter-marker distance and, hence, a 20K low density customized SNP array from HD chip could be designed for genomic selection in these cattle else the 54K Bead Chip as such will be useful.

  14. A meiotic linkage map of the silver fox, aligned and compared to the canine genome.

    PubMed

    Kukekova, Anna V; Trut, Lyudmila N; Oskina, Irina N; Johnson, Jennifer L; Temnykh, Svetlana V; Kharlamova, Anastasiya V; Shepeleva, Darya V; Gulievich, Rimma G; Shikhevich, Svetlana G; Graphodatsky, Alexander S; Aguirre, Gustavo D; Acland, Gregory M

    2007-03-01

    A meiotic linkage map is essential for mapping traits of interest and is often the first step toward understanding a cryptic genome. Specific strains of silver fox (a variant of the red fox, Vulpes vulpes), which segregate behavioral and morphological phenotypes, create a need for such a map. One such strain, selected for docility, exhibits friendly dog-like responses to humans, in contrast to another strain selected for aggression. Development of a fox map is facilitated by the known cytogenetic homologies between the dog and fox, and by the availability of high resolution canine genome maps and sequence data. Furthermore, the high genomic sequence identity between dog and fox allows adaptation of canine microsatellites for genotyping and meiotic mapping in foxes. Using 320 such markers, we have constructed the first meiotic linkage map of the fox genome. The resulting sex-averaged map covers 16 fox autosomes and the X chromosome with an average inter-marker distance of 7.5 cM. The total map length corresponds to 1480.2 cM. From comparison of sex-averaged meiotic linkage maps of the fox and dog genomes, suppression of recombination in pericentromeric regions of the metacentric fox chromosomes was apparent, relative to the corresponding segments of acrocentric dog chromosomes. Alignment of the fox meiotic map against the 7.6x canine genome sequence revealed high conservation of marker order between homologous regions of the two species. The fox meiotic map provides a critical tool for genetic studies in foxes and identification of genetic loci and genes implicated in fox domestication.

  15. Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes.

    PubMed

    Long, Ji-Rong; Zhao, Lan-Juan; Liu, Peng-Yuan; Lu, Yan; Dvornyk, Volodymyr; Shen, Hui; Liu, Yong-Jun; Zhang, Yuan-Yuan; Xiong, Dong-Hai; Xiao, Peng; Deng, Hong-Wen

    2004-05-24

    The adequacy of association studies for complex diseases depends critically on the existence of linkage disequilibrium (LD) between functional alleles and surrounding SNP markers. We examined the patterns of LD and haplotype distribution in eight candidate genes for osteoporosis and/or obesity using 31 SNPs in 1,873 subjects. These eight genes are apolipoprotein E (APOE), type I collagen alpha1 (COL1A1), estrogen receptor-alpha (ER-alpha), leptin receptor (LEPR), parathyroid hormone (PTH)/PTH-related peptide receptor type 1 (PTHR1), transforming growth factor-beta1 (TGF-beta1), uncoupling protein 3 (UCP3), and vitamin D (1,25-dihydroxyvitamin D3) receptor (VDR). Yin yang haplotypes, two high-frequency haplotypes composed of completely mismatching SNP alleles, were examined. To quantify LD patterns, two common measures of LD, D' and r2, were calculated for the SNPs within the genes. The haplotype distribution varied in the different genes. Yin yang haplotypes were observed only in PTHR1 and UCP3. D' ranged from 0.020 to 1.000 with the average of 0.475, whereas the average r2 was 0.158 (ranging from 0.000 to 0.883). A decay of LD was observed as the intermarker distance increased, however, there was a great difference in LD characteristics of different genes or even in different regions within gene. The differences in haplotype distributions and LD patterns among the genes underscore the importance of characterizing genomic regions of interest prior to association studies.

  16. Toward quantitative fluorescence microscopy with DNA origami nanorulers.

    PubMed

    Beater, Susanne; Raab, Mario; Tinnefeld, Philip

    2014-01-01

    The dynamic development of fluorescence microscopy has created a large number of new techniques, many of which are able to overcome the diffraction limit. This chapter describes the use of DNA origami nanostructures as scaffold for quantifying microscope properties such as sensitivity and resolution. The DNA origami technique enables placing of a defined number of fluorescent dyes in programmed geometries. We present a variety of DNA origami nanorulers that include nanorulers with defined labeling density and defined distances between marks. The chapter summarizes the advantages such as practically free choice of dyes and labeling density and presents examples of nanorulers in use. New triangular DNA origami nanorulers that do not require photoinduced switching by imaging transient binding to DNA nanostructures are also reported. Finally, we simulate fluorescence images of DNA origami nanorulers and reveal that the optimal DNA nanoruler for a specific application has an intermark distance that is roughly 1.3-fold the expected optical resolution. © 2014 Elsevier Inc. All rights reserved.

  17. Genome evolution in Reptilia: in silico chicken mapping of 12,000 BAC-end sequences from two reptiles and a basal bird

    PubMed Central

    2009-01-01

    Background With the publication of the draft chicken genome and the recent production of several BAC clone libraries from non-avian reptiles and birds, it is now possible to undertake more detailed comparative genomic studies in Reptilia. Of interest in particular are the genomic events that transformed the large, repeat-rich genomes of mammals and non-avian reptiles into the minimalist chicken genome. We have used paired BAC end sequences (BESs) from the American alligator (Alligator mississippiensis), painted turtle (Chrysemys picta) and emu (Dromaius novaehollandiae) to investigate patterns of sequence divergence, gene and retroelement content, and microsynteny between these species and chicken. Results From a total of 11,967 curated BESs, we successfully mapped 725, 773 and 2597 sequences in alligator, turtle, and emu, respectively, to sites in the draft chicken genome using a stringent BLAST protocol. Most commonly, sequences mapped to a single site in the chicken genome. Of 1675, 1828 and 2936 paired BESs obtained for alligator, turtle, and emu, respectively, a total of 34 (alligator, 2%), 24 (turtle, 1.3%) and 479 (emu, 16.3%) pairs were found to map with high confidence and in the correct orientation and with BAC-sized intermarker distances to single chicken chromosomes, including 25 such paired hits in emu mapping to the chicken Z chromosome. By determining the insert sizes of a subset of BAC clones from these three species, we also found a significant correlation between the intermarker distance in alligator and turtle and in chicken, with slopes as expected on the basis of the ratio of the genome sizes. Conclusion Our results suggest that a large number of small-scale chromosomal rearrangements and deletions in the lineage leading to chicken have drastically reduced the number of detected syntenies observed between the chicken and alligator, turtle, and emu genomes and imply that small deletions occurring widely throughout the genomes of reptilian and avian ancestors led to the ~50% reduction in genome size observed in birds compared to reptiles. We have also mapped and identified likely gene regions in hundreds of new BAC clones from these species. PMID:19607659

  18. Genome evolution in Reptilia: in silico chicken mapping of 12,000 BAC-end sequences from two reptiles and a basal bird.

    PubMed

    Chapus, Charles; Edwards, Scott V

    2009-07-14

    With the publication of the draft chicken genome and the recent production of several BAC clone libraries from non-avian reptiles and birds, it is now possible to undertake more detailed comparative genomic studies in Reptilia. Of interest in particular are the genomic events that transformed the large, repeat-rich genomes of mammals and non-avian reptiles into the minimalist chicken genome. We have used paired BAC end sequences (BESs) from the American alligator (Alligator mississippiensis), painted turtle (Chrysemys picta) and emu (Dromaius novaehollandiae) to investigate patterns of sequence divergence, gene and retroelement content, and microsynteny between these species and chicken. From a total of 11,967 curated BESs, we successfully mapped 725, 773 and 2597 sequences in alligator, turtle, and emu, respectively, to sites in the draft chicken genome using a stringent BLAST protocol. Most commonly, sequences mapped to a single site in the chicken genome. Of 1675, 1828 and 2936 paired BESs obtained for alligator, turtle, and emu, respectively, a total of 34 (alligator, 2%), 24 (turtle, 1.3%) and 479 (emu, 16.3%) pairs were found to map with high confidence and in the correct orientation and with BAC-sized intermarker distances to single chicken chromosomes, including 25 such paired hits in emu mapping to the chicken Z chromosome. By determining the insert sizes of a subset of BAC clones from these three species, we also found a significant correlation between the intermarker distance in alligator and turtle and in chicken, with slopes as expected on the basis of the ratio of the genome sizes. Our results suggest that a large number of small-scale chromosomal rearrangements and deletions in the lineage leading to chicken have drastically reduced the number of detected syntenies observed between the chicken and alligator, turtle, and emu genomes and imply that small deletions occurring widely throughout the genomes of reptilian and avian ancestors led to the ~50% reduction in genome size observed in birds compared to reptiles. We have also mapped and identified likely gene regions in hundreds of new BAC clones from these species.

  19. Action Sport Cameras as an Instrument to Perform a 3D Underwater Motion Analysis.

    PubMed

    Bernardina, Gustavo R D; Cerveri, Pietro; Barros, Ricardo M L; Marins, João C B; Silvatti, Amanda P

    2016-01-01

    Action sport cameras (ASC) are currently adopted mainly for entertainment purposes but their uninterrupted technical improvements, in correspondence of cost decreases, are going to disclose them for three-dimensional (3D) motion analysis in sport gesture study and athletic performance evaluation quantitatively. Extending this technology to sport analysis however still requires a methodologic step-forward to making ASC a metric system, encompassing ad-hoc camera setup, image processing, feature tracking, calibration and 3D reconstruction. Despite traditional laboratory analysis, such requirements become an issue when coping with both indoor and outdoor motion acquisitions of athletes. In swimming analysis for example, the camera setup and the calibration protocol are particularly demanding since land and underwater cameras are mandatory. In particular, the underwater camera calibration can be an issue affecting the reconstruction accuracy. In this paper, the aim is to evaluate the feasibility of ASC for 3D underwater analysis by focusing on camera setup and data acquisition protocols. Two GoPro Hero3+ Black (frequency: 60Hz; image resolutions: 1280×720/1920×1080 pixels) were located underwater into a swimming pool, surveying a working volume of about 6m3. A two-step custom calibration procedure, consisting in the acquisition of one static triad and one moving wand, carrying nine and one spherical passive markers, respectively, was implemented. After assessing camera parameters, a rigid bar, carrying two markers at known distance, was acquired in several positions within the working volume. The average error upon the reconstructed inter-marker distances was less than 2.5mm (1280×720) and 1.5mm (1920×1080). The results of this study demonstrate that the calibration of underwater ASC is feasible enabling quantitative kinematic measurements with accuracy comparable to traditional motion capture systems.

  20. Action Sport Cameras as an Instrument to Perform a 3D Underwater Motion Analysis

    PubMed Central

    Cerveri, Pietro; Barros, Ricardo M. L.; Marins, João C. B.; Silvatti, Amanda P.

    2016-01-01

    Action sport cameras (ASC) are currently adopted mainly for entertainment purposes but their uninterrupted technical improvements, in correspondence of cost decreases, are going to disclose them for three-dimensional (3D) motion analysis in sport gesture study and athletic performance evaluation quantitatively. Extending this technology to sport analysis however still requires a methodologic step-forward to making ASC a metric system, encompassing ad-hoc camera setup, image processing, feature tracking, calibration and 3D reconstruction. Despite traditional laboratory analysis, such requirements become an issue when coping with both indoor and outdoor motion acquisitions of athletes. In swimming analysis for example, the camera setup and the calibration protocol are particularly demanding since land and underwater cameras are mandatory. In particular, the underwater camera calibration can be an issue affecting the reconstruction accuracy. In this paper, the aim is to evaluate the feasibility of ASC for 3D underwater analysis by focusing on camera setup and data acquisition protocols. Two GoPro Hero3+ Black (frequency: 60Hz; image resolutions: 1280×720/1920×1080 pixels) were located underwater into a swimming pool, surveying a working volume of about 6m3. A two-step custom calibration procedure, consisting in the acquisition of one static triad and one moving wand, carrying nine and one spherical passive markers, respectively, was implemented. After assessing camera parameters, a rigid bar, carrying two markers at known distance, was acquired in several positions within the working volume. The average error upon the reconstructed inter-marker distances was less than 2.5mm (1280×720) and 1.5mm (1920×1080). The results of this study demonstrate that the calibration of underwater ASC is feasible enabling quantitative kinematic measurements with accuracy comparable to traditional motion capture systems. PMID:27513846

  1. Large-Scale Development of Cost-Effective Single-Nucleotide Polymorphism Marker Assays for Genetic Mapping in Pigeonpea and Comparative Mapping in Legumes

    PubMed Central

    Saxena, Rachit K.; Varma Penmetsa, R.; Upadhyaya, Hari D.; Kumar, Ashish; Carrasquilla-Garcia, Noelia; Schlueter, Jessica A.; Farmer, Andrew; Whaley, Adam M.; Sarma, Birinchi K.; May, Gregory D.; Cook, Douglas R.; Varshney, Rajeev K.

    2012-01-01

    Single-nucleotide polymorphisms (SNPs, >2000) were discovered by using RNA-seq and allele-specific sequencing approaches in pigeonpea (Cajanus cajan). For making the SNP genotyping cost-effective, successful competitive allele-specific polymerase chain reaction (KASPar) assays were developed for 1616 SNPs and referred to as PKAMs (pigeonpea KASPar assay markers). Screening of PKAMs on 24 genotypes [23 from cultivated species and 1 wild species (Cajanus scarabaeoides)] defined a set of 1154 polymorphic markers (77.4%) with a polymorphism information content (PIC) value from 0.04 to 0.38. One thousand and ninety-four PKAMs showed polymorphisms between parental lines of the reference mapping population (C. cajan ICP 28 × C. scarabaeoides ICPW 94). By using high-quality marker genotyping data on 167 F2 lines from the population, a comprehensive genetic map comprising 875 PKAMs with an average inter-marker distance of 1.11 cM was developed. Previously mapped 35 simple sequence repeat markers were integrated into the PKAM map and an integrated genetic map of 996.21 cM was constructed. Mapped PKAMs showed a higher degree of synteny with the genome of Glycine max followed by Medicago truncatula and Lotus japonicus and least with Vigna unguiculata. These PKAMs will be useful for genetics research and breeding applications in pigeonpea and for utilizing genome information from other legume species. PMID:23103470

  2. Genome-wide population structure and evolutionary history of the Frizarta dairy sheep.

    PubMed

    Kominakis, A; Hager-Theodorides, A L; Saridaki, A; Antonakos, G; Tsiamis, G

    2017-10-01

    In the present study, we used genomic data, generated with a medium density single nucleotide polymorphisms (SNP) array, to acquire more information on the population structure and evolutionary history of the synthetic Frizarta dairy sheep. First, two typical measures of linkage disequilibrium (LD) were estimated at various physical distances that were then used to make inferences on the effective population size at key past time points. Population structure was also assessed by both multidimensional scaling analysis and k-means clustering on the distance matrix obtained from the animals' genomic relationships. The Wright's fixation F ST index was also employed to assess herds' genetic homogeneity and to indirectly estimate past migration rates. The Wright's fixation F IS index and genomic inbreeding coefficients based on the genomic relationship matrix as well as on runs of homozygosity were also estimated. The Frizarta breed displays relatively low LD levels with r 2 and |D'| equal to 0.18 and 0.50, respectively, at an average inter-marker distance of 31 kb. Linkage disequilibrium decayed rapidly by distance and persisted over just a few thousand base pairs. Rate of LD decay (β) varied widely among the 26 autosomes with larger values estimated for shorter chromosomes (e.g. β=0.057, for OAR6) and smaller values for longer ones (e.g. β=0.022, for OAR2). The inferred effective population size at the beginning of the breed's formation was as high as 549, was then reduced to 463 in 1981 (end of the breed's formation) and further declined to 187, one generation ago. Multidimensional scaling analysis and k-means clustering suggested a genetically homogenous population, F ST estimates indicated relatively low genetic differentiation between herds, whereas a heat map of the animals' genomic kinship relationships revealed a stratified population, at a herd level. Estimates of genomic inbreeding coefficients suggested that most recent parental relatedness may have been a major determinant of the current effective population size. A denser than the 50k SNP panel may be more beneficial when performing genome wide association studies in the breed.

  3. A Novel Marker Based Method to Teeth Alignment in MRI

    NASA Astrophysics Data System (ADS)

    Luukinen, Jean-Marc; Aalto, Daniel; Malinen, Jarmo; Niikuni, Naoko; Saunavaara, Jani; Jääsaari, Päivi; Ojalammi, Antti; Parkkola, Riitta; Soukka, Tero; Happonen, Risto-Pekka

    2018-04-01

    Magnetic resonance imaging (MRI) can precisely capture the anatomy of the vocal tract. However, the crowns of teeth are not visible in standard MRI scans. In this study, a marker-based teeth alignment method is presented and evaluated. Ten patients undergoing orthognathic surgery were enrolled. Supraglottal airways were imaged preoperatively using structural MRI. MRI visible markers were developed, and they were attached to maxillary teeth and corresponding locations on the dental casts. Repeated measurements of intermarker distances in MRI and in a replica model was compared using linear regression analysis. Dental cast MRI and corresponding caliper measurements did not differ significantly. In contrast, the marker locations in vivo differed somewhat from the dental cast measurements likely due to marker placement inaccuracies. The markers were clearly visible in MRI and allowed for dental models to be aligned to head and neck MRI scans.

  4. Genetic linkage map of a wild genome: genomic structure, recombination and sexual dimorphism in bighorn sheep

    PubMed Central

    2010-01-01

    Background The construction of genetic linkage maps in free-living populations is a promising tool for the study of evolution. However, such maps are rare because it is difficult to develop both wild pedigrees and corresponding sets of molecular markers that are sufficiently large. We took advantage of two long-term field studies of pedigreed individuals and genomic resources originally developed for domestic sheep (Ovis aries) to construct a linkage map for bighorn sheep, Ovis canadensis. We then assessed variability in genomic structure and recombination rates between bighorn sheep populations and sheep species. Results Bighorn sheep population-specific maps differed slightly in contiguity but were otherwise very similar in terms of genomic structure and recombination rates. The joint analysis of the two pedigrees resulted in a highly contiguous map composed of 247 microsatellite markers distributed along all 26 autosomes and the X chromosome. The map is estimated to cover about 84% of the bighorn sheep genome and contains 240 unique positions spanning a sex-averaged distance of 3051 cM with an average inter-marker distance of 14.3 cM. Marker synteny, order, sex-averaged interval lengths and sex-averaged total map lengths were all very similar between sheep species. However, in contrast to domestic sheep, but consistent with the usual pattern for a placental mammal, recombination rates in bighorn sheep were significantly greater in females than in males (~12% difference), resulting in an autosomal female map of 3166 cM and an autosomal male map of 2831 cM. Despite differing genome-wide patterns of heterochiasmy between the sheep species, sexual dimorphism in recombination rates was correlated between orthologous intervals. Conclusions We have developed a first-generation bighorn sheep linkage map that will facilitate future studies of the genetic architecture of trait variation in this species. While domestication has been hypothesized to be responsible for the elevated mean recombination rate observed in domestic sheep, our results suggest that it is a characteristic of Ovis species. However, domestication may have played a role in altering patterns of heterochiasmy. Finally, we found that interval-specific patterns of sexual dimorphism were preserved among closely related Ovis species, possibly due to the conserved position of these intervals relative to the centromeres and telomeres. This study exemplifies how transferring genomic resources from domesticated species to close wild relative can benefit evolutionary ecologists while providing insights into the evolution of genomic structure and recombination rates of domesticated species. PMID:20920197

  5. High-density genetic map of Miscanthus sinensis reveals inheritance of zebra stripe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Siyao; Clark, Lindsay V.; Swaminathan, Kankshita

    Miscanthus is a perennial C4 grass that has recently become an important bioenergy crop. The efficiency of breeding improved Miscanthus biomass cultivars could be greatly increased by marker-assisted selection. Thus, a high-density genetic map is critical to Miscanthus improvement. In this study, a mapping population of 261 F1 progeny was developed from a cross between two diploid M. sinensis cultivars, ‘Strictus’ and ‘Kaskade’. High-density genetic maps for the two parents were produced with 3044 newly developed single nucleotide polymorphisms (SNPs) obtained from restriction site-associated DNA sequencing, and 138 previously mapped GoldenGate SNPs. The female parent (‘Strictus’) map spanned 1599 cM,more » with 1989 SNPs on 19 linkage groups, and an average intermarker spacing of 0.8 cM. The length of the male parent (‘Kaskade’) map was 1612 cM, with 1821 SNPs, and an average intermarker spacing of 0.9 cM. The utility of the map was confirmed by locating quantitative trait loci (QTL) for the zebra-striped trait, which was segregating in this population. Three QTL for zebra-striped presence/absence (zb1, zb2 on LG 7, and zb3 on LG 10) and three for zebra-striped intensity (zbi1, zbi2, zbi3 on LGs 7, 10, 3) were identified. Each allele that caused striping was recessive. Incomplete penetrance was observed for each zb QTL, but penetrance was greatest when two or more zb QTL were homozygous for the causative alleles. Similarly, the intensity of striping was greatest when two or more zbi QTL were homozygous for alleles that conferred the trait. Comparative mapping indicated putative correspondence between zb3 and/or zbi2 on LG 10 to previously sequenced genes conferring zebra stripe in maize and rice. These results demonstrate that the new map is useful for identifying marker–trait associations. The mapped markers will become a valuable community resource, facilitating comparisons among studies and the breeding of Miscanthus.« less

  6. High-density genetic map of Miscanthus sinensis reveals inheritance of zebra stripe

    DOE PAGES

    Liu, Siyao; Clark, Lindsay V.; Swaminathan, Kankshita; ...

    2015-05-06

    Miscanthus is a perennial C4 grass that has recently become an important bioenergy crop. The efficiency of breeding improved Miscanthus biomass cultivars could be greatly increased by marker-assisted selection. Thus, a high-density genetic map is critical to Miscanthus improvement. In this study, a mapping population of 261 F1 progeny was developed from a cross between two diploid M. sinensis cultivars, ‘Strictus’ and ‘Kaskade’. High-density genetic maps for the two parents were produced with 3044 newly developed single nucleotide polymorphisms (SNPs) obtained from restriction site-associated DNA sequencing, and 138 previously mapped GoldenGate SNPs. The female parent (‘Strictus’) map spanned 1599 cM,more » with 1989 SNPs on 19 linkage groups, and an average intermarker spacing of 0.8 cM. The length of the male parent (‘Kaskade’) map was 1612 cM, with 1821 SNPs, and an average intermarker spacing of 0.9 cM. The utility of the map was confirmed by locating quantitative trait loci (QTL) for the zebra-striped trait, which was segregating in this population. Three QTL for zebra-striped presence/absence (zb1, zb2 on LG 7, and zb3 on LG 10) and three for zebra-striped intensity (zbi1, zbi2, zbi3 on LGs 7, 10, 3) were identified. Each allele that caused striping was recessive. Incomplete penetrance was observed for each zb QTL, but penetrance was greatest when two or more zb QTL were homozygous for the causative alleles. Similarly, the intensity of striping was greatest when two or more zbi QTL were homozygous for alleles that conferred the trait. Comparative mapping indicated putative correspondence between zb3 and/or zbi2 on LG 10 to previously sequenced genes conferring zebra stripe in maize and rice. These results demonstrate that the new map is useful for identifying marker–trait associations. The mapped markers will become a valuable community resource, facilitating comparisons among studies and the breeding of Miscanthus.« less

  7. Novel SSR Markers from BAC-End Sequences, DArT Arrays and a Comprehensive Genetic Map with 1,291 Marker Loci for Chickpea (Cicer arietinum L.)

    PubMed Central

    Nayak, Spurthi N.; Varghese, Nicy; Shah, Trushar M.; Penmetsa, R. Varma; Thirunavukkarasu, Nepolean; Gudipati, Srivani; Gaur, Pooran M.; Kulwal, Pawan L.; Upadhyaya, Hari D.; KaviKishor, Polavarapu B.; Winter, Peter; Kahl, Günter; Town, Christopher D.; Kilian, Andrzej; Cook, Douglas R.; Varshney, Rajeev K.

    2011-01-01

    Chickpea (Cicer arietinum L.) is the third most important cool season food legume, cultivated in arid and semi-arid regions of the world. The goal of this study was to develop novel molecular markers such as microsatellite or simple sequence repeat (SSR) markers from bacterial artificial chromosome (BAC)-end sequences (BESs) and diversity arrays technology (DArT) markers, and to construct a high-density genetic map based on recombinant inbred line (RIL) population ICC 4958 (C. arietinum)×PI 489777 (C. reticulatum). A BAC-library comprising 55,680 clones was constructed and 46,270 BESs were generated. Mining of these BESs provided 6,845 SSRs, and primer pairs were designed for 1,344 SSRs. In parallel, DArT arrays with ca. 15,000 clones were developed, and 5,397 clones were found polymorphic among 94 genotypes tested. Screening of newly developed BES-SSR markers and DArT arrays on the parental genotypes of the RIL mapping population showed polymorphism with 253 BES-SSR markers and 675 DArT markers. Segregation data obtained for these polymorphic markers and 494 markers data compiled from published reports or collaborators were used for constructing the genetic map. As a result, a comprehensive genetic map comprising 1,291 markers on eight linkage groups (LGs) spanning a total of 845.56 cM distance was developed (http://cmap.icrisat.ac.in/cmap/sm/cp/thudi/). The number of markers per linkage group ranged from 68 (LG 8) to 218 (LG 3) with an average inter-marker distance of 0.65 cM. While the developed resource of molecular markers will be useful for genetic diversity, genetic mapping and molecular breeding applications, the comprehensive genetic map with integrated BES-SSR markers will facilitate its anchoring to the physical map (under construction) to accelerate map-based cloning of genes in chickpea and comparative genome evolution studies in legumes. PMID:22102885

  8. A Genomewide Admixture Mapping Panel for Hispanic/Latino Populations

    PubMed Central

    Mao, Xianyun ; Bigham, Abigail W. ; Mei, Rui ; Gutierrez, Gerardo ; Weiss, Ken M. ; Brutsaert, Tom D. ; Leon-Velarde, Fabiola ; Moore, Lorna G. ; Vargas, Enrique ; McKeigue, Paul M. ; Shriver, Mark D. ; Parra, Esteban J. 

    2007-01-01

    Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and diseases showing prevalence differences among populations. Efficient application of this method requires the use of a genomewide panel of ancestry-informative markers (AIMs) to infer the population of origin of chromosomal regions in admixed individuals. Genomewide AM panels with markers showing high frequency differences between West African and European populations are already available for disease-gene discovery in African Americans. However, no such a map is yet available for Hispanic/Latino populations, which are the result of two-way admixture between Native American and European populations or of three-way admixture of Native American, European, and West African populations. Here, we report a genomewide AM panel with 2,120 AIMs showing high frequency differences between Native American and European populations. The average intermarker genetic distance is ∼1.7 cM. The panel was identified by genotyping, with the Affymetrix GeneChip Human Mapping 500K array, a population sample with European ancestry, a Mesoamerican sample comprising Maya and Nahua from Mexico, and a South American sample comprising Aymara/Quechua from Bolivia and Quechua from Peru. The main criteria for marker selection were both high information content for Native American/European ancestry (measured as the standardized variance of the allele frequencies, also known as “f value”) and small frequency differences between the Mesoamerican and South American samples. This genomewide AM panel will make it possible to apply AM approaches in many admixed populations throughout the Americas. PMID:17503334

  9. Development of a robust MRI fiducial system for automated fusion of MR-US abdominal images.

    PubMed

    Favazza, Christopher P; Gorny, Krzysztof R; Callstrom, Matthew R; Kurup, Anil N; Washburn, Michael; Trester, Pamela S; Fowler, Charles L; Hangiandreou, Nicholas J

    2018-05-21

    We present the development of a two-component magnetic resonance (MR) fiducial system, that is, a fiducial marker device combined with an auto-segmentation algorithm, designed to be paired with existing ultrasound probe tracking and image fusion technology to automatically fuse MR and ultrasound (US) images. The fiducial device consisted of four ~6.4 mL cylindrical wells filled with 1 g/L copper sulfate solution. The algorithm was designed to automatically segment the device in clinical abdominal MR images. The algorithm's detection rate and repeatability were investigated through a phantom study and in human volunteers. The detection rate was 100% in all phantom and human images. The center-of-mass of the fiducial device was robustly identified with maximum variations of 2.9 mm in position and 0.9° in angular orientation. In volunteer images, average differences between algorithm-measured inter-marker spacings and actual separation distances were 0.53 ± 0.36 mm. "Proof-of-concept" automatic MR-US fusions were conducted with sets of images from both a phantom and volunteer using a commercial prototype system, which was built based on the above findings. Image fusion accuracy was measured to be within 5 mm for breath-hold scanning. These results demonstrate the capability of this approach to automatically fuse US and MR images acquired across a wide range of clinical abdominal pulse sequences. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  10. Construction of a microsatellites-based linkage map for the white grouper (Epinephelus aeneus).

    PubMed

    Dor, Lior; Shirak, Andrey; Gorshkov, Sergei; Band, Mark R; Korol, Abraham; Ronin, Yefim; Curzon, Arie; Hulata, Gideon; Seroussi, Eyal; Ron, Micha

    2014-06-05

    The white grouper (Epinephelus aeneus) is a promising candidate for domestication and aquaculture due to its fast growth, excellent taste, and high market price. A linkage map is an essential framework for mapping quantitative trait loci for economic traits and the study of genome evolution. DNA of a single individual was deep-sequenced, and microsatellite markers were identified in 177 of the largest scaffolds of the sequence assembly. The success rate of developing polymorphic homologous markers was 94.9% compared with 63.1% of heterologous markers from other grouper species. Of the 12 adult mature fish present in the broodstock tank, two males and two females were identified as parents of the assigned offspring by parenthood analysis using 34 heterologous markers. A single full-sib family of 48 individuals was established for the construction of first-generation linkage maps based on genotyping data of 222 microsatellites. The markers were assigned to 24 linkage groups in accordance to the 24 chromosomal pairs. The female and male maps consisting of 203 and 202 markers spanned 1053 and 886 cM, with an average intermarker distance of 5.8 and 5.0 cM, respectively. Mapping of markers to linkage groups ends was enriched by using markers originating from scaffolds harboring telomeric repeat-containing RNA. Comparative mapping showed high synteny relationships among the white grouper, kelp grouper (E. bruneus), orange-spotted grouper (E. coioides), and Nile tilapia (Oreochromis niloticus). Thus, it would be useful to integrate the markers that were developed for different groupers, depending on sharing of sequence data, into a comprehensive consensus map. Copyright © 2014 Dor et al.

  11. Assessment in Higher Education: The Potential for a Community of Practice to Improve Inter-Marker Reliability

    ERIC Educational Resources Information Center

    Herbert, Ian P.; Joyce, John; Hassall, Trevor

    2014-01-01

    The design, delivery and assessment of a complete educational scheme, such as a degree programme or a professional qualification course, is a complex matter. Maintaining alignment between the stated aims of the curriculum and the scoring of student achievement is an overarching concern. The potential for drift across individual aspects of an…

  12. A Primary Assembly of a Bovine Haplotype Block Map Based on a 15,036-Single-Nucleotide Polymorphism Panel Genotyped in Holstein–Friesian Cattle

    PubMed Central

    Khatkar, Mehar S.; Zenger, Kyall R.; Hobbs, Matthew; Hawken, Rachel J.; Cavanagh, Julie A. L.; Barris, Wes; McClintock, Alexander E.; McClintock, Sara; Thomson, Peter C.; Tier, Bruce; Nicholas, Frank W.; Raadsma, Herman W.

    2007-01-01

    Analysis of data on 1000 Holstein–Friesian bulls genotyped for 15,036 single-nucleotide polymorphisms (SNPs) has enabled genomewide identification of haplotype blocks and tag SNPs. A final subset of 9195 SNPs in Hardy–Weinberg equilibrium and mapped on autosomes on the bovine sequence assembly (release Btau 3.1) was used in this study. The average intermarker spacing was 251.8 kb. The average minor allele frequency (MAF) was 0.29 (0.05–0.5). Following recent precedents in human HapMap studies, a haplotype block was defined where 95% of combinations of SNPs within a region are in very high linkage disequilibrium. A total of 727 haplotype blocks consisting of ≥3 SNPs were identified. The average block length was 69.7 ± 7.7 kb, which is ∼5–10 times larger than in humans. These blocks comprised a total of 2964 SNPs and covered 50,638 kb of the sequence map, which constitutes 2.18% of the length of all autosomes. A set of tag SNPs, which will be useful for further fine-mapping studies, has been identified. Overall, the results suggest that as many as 75,000–100,000 tag SNPs would be needed to track all important haplotype blocks in the bovine genome. This would require ∼250,000 SNPs in the discovery phase. PMID:17435229

  13. Collecting Kinematic Data on a Ski Track with Optoelectronic Stereophotogrammetry: A Methodological Study Assessing the Feasibility of Bringing the Biomechanics Lab to the Field.

    PubMed

    Spörri, Jörg; Schiefermüller, Christian; Müller, Erich

    2016-01-01

    In the laboratory, optoelectronic stereophotogrammetry is one of the most commonly used motion capture systems; particularly, when position- or orientation-related analyses of human movements are intended. However, for many applied research questions, field experiments are indispensable, and it is not a priori clear whether optoelectronic stereophotogrammetric systems can be expected to perform similarly to in-lab experiments. This study aimed to assess the instrumental errors of kinematic data collected on a ski track using optoelectronic stereophotogrammetry, and to investigate the magnitudes of additional skiing-specific errors and soft tissue/suit artifacts. During a field experiment, the kinematic data of different static and dynamic tasks were captured by the use of 24 infrared-cameras. The distances between three passive markers attached to a rigid bar were stereophotogrammetrically reconstructed and, subsequently, were compared to the manufacturer-specified exact values. While at rest or skiing at low speed, the optoelectronic stereophotogrammetric system's accuracy and precision for determining inter-marker distances were found to be comparable to those known for in-lab experiments (< 1 mm). However, when measuring a skier's kinematics under "typical" skiing conditions (i.e., high speeds, inclined/angulated postures and moderate snow spraying), additional errors were found to occur for distances between equipment-fixed markers (total measurement errors: 2.3 ± 2.2 mm). Moreover, for distances between skin-fixed markers, such as the anterior hip markers, additional artifacts were observed (total measurement errors: 8.3 ± 7.1 mm). In summary, these values can be considered sufficient for the detection of meaningful position- or orientation-related differences in alpine skiing. However, it must be emphasized that the use of optoelectronic stereophotogrammetry on a ski track is seriously constrained by limited practical usability, small-sized capture volumes and the occurrence of extensive snow spraying (which results in marker obscuration). The latter limitation possibly might be overcome by the use of more sophisticated cluster-based marker sets.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nikali, K.; Isosomppi, J.; Suomalainen, A.

    Infantile onset spinocerebellar ataxia (IOSCA) is a progressive neurological disorder of unknown etiology. It is inherited as an autosomal recessive trait and has so far been reported in just 19 Finnish patients in 13 separate families. We have previously assigned the IOSCA locus (HGMW-approved symbol SCA8) to chromosome 10q, where no previously identified ataxia loci are located. Haplotype analysis combined with genealogical data provided evidence that all the IOSCA cases in Finland originate from a single 30- to 40-generation-old founder mutation. By analyzing extended disease haplotypes observed today, the IOSCA locus can now be restricted to a region between twomore » adjacent microsatellites, D10S192 and D10S1265, with no genetic intermarker distance. We have constructed a detailed physical map of this 270-kb IOSCA region and cytogenetically localized it to 10q24. We have also assigned two previously known genes, PAX2 and CYP17, more precisely into this region, but the sequence analysis of coding regions of these two genes has not revealed mutations in an IOSCA patient. The obtained long-range clones will form the basis for the isolation of a novel ataxia gene. 42 refs., 3 figs.« less

  15. Mapping Quantitative Trait Loci Controlling High Iron and Zinc Content in Self and Open Pollinated Grains of Pearl Millet [Pennisetum glaucum (L.) R. Br.

    PubMed Central

    Kumar, Sushil; Hash, Charles T.; Thirunavukkarasu, Nepolean; Singh, Govind; Rajaram, Vengaldas; Rathore, Abhishek; Senapathy, Senthilvel; Mahendrakar, Mahesh D.; Yadav, Rattan S.; Srivastava, Rakesh K.

    2016-01-01

    Pearl millet is a multipurpose grain/fodder crop of the semi-arid tropics, feeding many of the world’s poorest and most undernourished people. Genetic variation among adapted pearl millet inbreds and hybrids suggests it will be possible to improve grain micronutrient concentrations by selective breeding. Using 305 loci, a linkage map was constructed to map QTLs for grain iron [Fe] and zinc [Zn] using replicated samples of 106 pearl millet RILs (F6) derived from ICMB 841-P3 × 863B-P2. The grains of the RIL population were evaluated for Fe and Zn content using atomic absorption spectrophotometer. Grain mineral concentrations ranged from 28.4 to 124.0 ppm for Fe and 28.7 to 119.8 ppm for Zn. Similarly, grain Fe and Zn in open pollinated seeds ranged between 22.4–77.4 and 21.9–73.7 ppm, respectively. Mapping with 305 (96 SSRs; 208 DArT) markers detected seven linkage groups covering 1749 cM (Haldane) with an average intermarker distance of 5.73 cM. On the basis of two environment phenotypic data, two co-localized QTLs for Fe and Zn content on linkage group (LG) 3 were identified by composite interval mapping (CIM). Fe QTL explained 19% phenotypic variation, whereas the Zn QTL explained 36% phenotypic variation. Likewise for open pollinated seeds, the QTL analysis led to the identification of two QTLs for grain Fe content on LG3 and 5, and two QTLs for grain Zn content on LG3 and 7. The total phenotypic variance for Fe and Zn QTLs in open pollinated seeds was 16 and 42%, respectively. Analysis of QTL × QTL and QTL × QTL × environment interactions indicated no major epistasis. PMID:27933068

  16. An Integrated Genomic Approach for Rapid Delineation of Candidate Genes Regulating Agro-Morphological Traits in Chickpea

    PubMed Central

    Saxena, Maneesha S.; Bajaj, Deepak; Das, Shouvik; Kujur, Alice; Kumar, Vinod; Singh, Mohar; Bansal, Kailash C.; Tyagi, Akhilesh K.; Parida, Swarup K.

    2014-01-01

    The identification and fine mapping of robust quantitative trait loci (QTLs)/genes governing important agro-morphological traits in chickpea still lacks systematic efforts at a genome-wide scale involving wild Cicer accessions. In this context, an 834 simple sequence repeat and single-nucleotide polymorphism marker-based high-density genetic linkage map between cultivated and wild parental accessions (Cicer arietinum desi cv. ICC 4958 and Cicer reticulatum wild cv. ICC 17160) was constructed. This inter-specific genetic map comprising eight linkage groups spanned a map length of 949.4 cM with an average inter-marker distance of 1.14 cM. Eleven novel major genomic regions harbouring 15 robust QTLs (15.6–39.8% R2 at 4.2–15.7 logarithm of odds) associated with four agro-morphological traits (100-seed weight, pod and branch number/plant and plant hairiness) were identified and mapped on chickpea chromosomes. Most of these QTLs showed positive additive gene effects with effective allelic contribution from ICC 4958, particularly for increasing seed weight (SW) and pod and branch number. One robust SW-influencing major QTL region (qSW4.2) has been narrowed down by combining QTL mapping with high-resolution QTL region-specific association analysis, differential expression profiling and gene haplotype-based association/LD mapping. This enabled to delineate a strong SW-regulating ABI3VP1 transcription factor (TF) gene at trait-specific QTL interval and consequently identified favourable natural allelic variants and superior high seed weight-specific haplotypes in the upstream regulatory region of this gene showing increased transcript expression during seed development. The genes (TFs) harbouring diverse trait-regulating QTLs, once validated and fine-mapped by our developed rapid integrated genomic approach and through gene/QTL map-based cloning, can be utilized as potential candidates for marker-assisted genetic enhancement of chickpea. PMID:25335477

  17. Collecting Kinematic Data on a Ski Track with Optoelectronic Stereophotogrammetry: A Methodological Study Assessing the Feasibility of Bringing the Biomechanics Lab to the Field

    PubMed Central

    Müller, Erich

    2016-01-01

    In the laboratory, optoelectronic stereophotogrammetry is one of the most commonly used motion capture systems; particularly, when position- or orientation-related analyses of human movements are intended. However, for many applied research questions, field experiments are indispensable, and it is not a priori clear whether optoelectronic stereophotogrammetric systems can be expected to perform similarly to in-lab experiments. This study aimed to assess the instrumental errors of kinematic data collected on a ski track using optoelectronic stereophotogrammetry, and to investigate the magnitudes of additional skiing-specific errors and soft tissue/suit artifacts. During a field experiment, the kinematic data of different static and dynamic tasks were captured by the use of 24 infrared-cameras. The distances between three passive markers attached to a rigid bar were stereophotogrammetrically reconstructed and, subsequently, were compared to the manufacturer-specified exact values. While at rest or skiing at low speed, the optoelectronic stereophotogrammetric system’s accuracy and precision for determining inter-marker distances were found to be comparable to those known for in-lab experiments (< 1 mm). However, when measuring a skier’s kinematics under “typical” skiing conditions (i.e., high speeds, inclined/angulated postures and moderate snow spraying), additional errors were found to occur for distances between equipment-fixed markers (total measurement errors: 2.3 ± 2.2 mm). Moreover, for distances between skin-fixed markers, such as the anterior hip markers, additional artifacts were observed (total measurement errors: 8.3 ± 7.1 mm). In summary, these values can be considered sufficient for the detection of meaningful position- or orientation-related differences in alpine skiing. However, it must be emphasized that the use of optoelectronic stereophotogrammetry on a ski track is seriously constrained by limited practical usability, small-sized capture volumes and the occurrence of extensive snow spraying (which results in marker obscuration). The latter limitation possibly might be overcome by the use of more sophisticated cluster-based marker sets. PMID:27560498

  18. A Study of Vicon System Positioning Performance.

    PubMed

    Merriaux, Pierre; Dupuis, Yohan; Boutteau, Rémi; Vasseur, Pascal; Savatier, Xavier

    2017-07-07

    Motion capture setups are used in numerous fields. Studies based on motion capture data can be found in biomechanical, sport or animal science. Clinical science studies include gait analysis as well as balance, posture and motor control. Robotic applications encompass object tracking. Today's life applications includes entertainment or augmented reality. Still, few studies investigate the positioning performance of motion capture setups. In this paper, we study the positioning performance of one player in the optoelectronic motion capture based on markers: Vicon system. Our protocol includes evaluations of static and dynamic performances. Mean error as well as positioning variabilities are studied with calibrated ground truth setups that are not based on other motion capture modalities. We introduce a new setup that enables directly estimating the absolute positioning accuracy for dynamic experiments contrary to state-of-the art works that rely on inter-marker distances. The system performs well on static experiments with a mean absolute error of 0.15 mm and a variability lower than 0.025 mm. Our dynamic experiments were carried out at speeds found in real applications. Our work suggests that the system error is less than 2 mm. We also found that marker size and Vicon sampling rate must be carefully chosen with respect to the speed encountered in the application in order to reach optimal positioning performance that can go to 0.3 mm for our dynamic study.

  19. Ignoring Intermarker Linkage Disequilibrium Induces False-Positive Evidence of Linkage for Consanguineous Pedigrees when Genotype Data Is Missing for Any Pedigree Member

    PubMed Central

    Li, Bingshan; Leal, Suzanne M.

    2008-01-01

    Missing genotype data can increase false-positive evidence for linkage when either parametric or nonparametric analysis is carried out ignoring intermarker linkage disequilibrium (LD). Previously it was demonstrated by Huang et al. [1] that no bias occurs in this situation for affected sib-pairs with unrelated parents when either both parents are genotyped or genotype data is available for two additional unaffected siblings when parental genotypes are missing. However, this is not the case for autosomal recessive consanguineous pedigrees, where missing genotype data for any pedigree member within a consanguinity loop can increase false-positive evidence of linkage. False-positive evidence for linkage is further increased when cryptic consanguinity is present. The amount of false-positive evidence for linkage, and which family members aid in its reduction, is highly dependent on which family members are genotyped. When parental genotype data is available, the false-positive evidence for linkage is usually not as strong as when parental genotype data is unavailable. For a pedigree with an affected proband whose first-cousin parents have been genotyped, further reduction in the false-positive evidence of linkage can be obtained by including genotype data from additional affected siblings of the proband or genotype data from the proband's sibling-grandparents. For the situation, when parental genotypes are unavailable, false-positive evidence for linkage can be reduced by including genotype data from either unaffected siblings of the proband or the proband's married-in-grandparents in the analysis. PMID:18073490

  20. An Efficient Strategy Combining SSR Markers- and Advanced QTL-seq-driven QTL Mapping Unravels Candidate Genes Regulating Grain Weight in Rice

    PubMed Central

    Daware, Anurag; Das, Sweta; Srivastava, Rishi; Badoni, Saurabh; Singh, Ashok K.; Agarwal, Pinky; Parida, Swarup K.; Tyagi, Akhilesh K.

    2016-01-01

    Development and use of genome-wide informative simple sequence repeat (SSR) markers and novel integrated genomic strategies are vital to drive genomics-assisted breeding applications and for efficient dissection of quantitative trait loci (QTLs) underlying complex traits in rice. The present study developed 6244 genome-wide informative SSR markers exhibiting in silico fragment length polymorphism based on repeat-unit variations among genomic sequences of 11 indica, japonica, aus, and wild rice accessions. These markers were mapped on diverse coding and non-coding sequence components of known cloned/candidate genes annotated from 12 chromosomes and revealed a much higher amplification (97%) and polymorphic potential (88%) along with wider genetic/functional diversity level (16–74% with a mean 53%) especially among accessions belonging to indica cultivar group, suggesting their utility in large-scale genomics-assisted breeding applications in rice. A high-density 3791 SSR markers-anchored genetic linkage map (IR 64 × Sonasal) spanning 2060 cM total map-length with an average inter-marker distance of 0.54 cM was generated. This reference genetic map identified six major genomic regions harboring robust QTLs (31% combined phenotypic variation explained with a 5.7–8.7 LOD) governing grain weight on six rice chromosomes. One strong grain weight major QTL region (OsqGW5.1) was narrowed-down by integrating traditional QTL mapping with high-resolution QTL region-specific integrated SSR and single nucleotide polymorphism markers-based QTL-seq analysis and differential expression profiling. This led us to delineate two natural allelic variants in two known cis-regulatory elements (RAV1AAT and CARGCW8GAT) of glycosyl hydrolase and serine carboxypeptidase genes exhibiting pronounced seed-specific differential regulation in low (Sonasal) and high (IR 64) grain weight mapping parental accessions. Our genome-wide SSR marker resource (polymorphic within/between diverse cultivar groups) and integrated genomic strategy can efficiently scan functionally relevant potential molecular tags (markers, candidate genes and alleles) regulating complex agronomic traits (grain weight) and expedite marker-assisted genetic enhancement in rice. PMID:27833617

  1. Sex-Specific Genetic Loci for Femoral Neck Bone Mass and Strength Identified in Inbred COP and DA Rats

    PubMed Central

    Alam, Imranul; Sun, Qiwei; Liu, Lixiang; Koller, Daniel L; Carr, Lucinda G; Econs, Michael J; Foroud, Tatiana; Turner, Charles H

    2008-01-01

    Introduction Hip fracture is the most devastating osteoporotic fracture type with significant morbidity and mortality. Several studies in humans identified chromosomal regions linked to hip size and bone mass. Animal models, particularly the inbred rat, serve as complementary approaches for studying the genetic influence on hip fragility. The purpose of this study is to identify sex-independent and sex-specific quantitative trait loci (QTLs) for femoral neck density, structure, and strength in inbred Copenhagen 2331 (COP) and Dark Agouti (DA) rats. Materials and Methods A total of 828 (405 males and 423 females) F2 progeny derived from the inbred COP and DA strains of rats were phenotyped for femoral neck volumetric BMD (vBMD), cross-sectional area, polar moment of inertia (Ip), neck width, ultimate force, and energy to break. A whole genome screen was performed using 93 microsatellite markers with an average intermarker distance of 20 cM. Recombination-based marker maps were generated using MAPMAKER/EXP from the COP × DA F2 data and compared with published Rat Genome Database (RGD) maps. These maps were used for genome-wide linkage analyses to detect sex-independent and sex-specific QTLs. Results Significant evidence of linkage (p < 0.01) for sex-independent QTLs were detected for (1) femoral neck vBMD on chromosomes (Chrs) 1, 6, 10, and 12, (2) femoral neck structure on Chrs 5, 7, 10, and 18, and (3) biomechanical properties on Chrs 1 and 4. Male-specific QTLs were discovered on Chrs 2, 9, and 18 for total vBMD, on Chr 17 for trabecular vBMD, on Chr 9 for total bone area, and on Chr 15 for ultimate force. A female-specific QTL was discovered on Chr 2 for ultimate force. The effect size of the individual QTL varied between 1% and 4%. Conclusions We detected evidence that sex-independent and sex-specific QTLs contribute to hip fragility in the inbred rat. Several QTLs regions identified in this study are homologous to human chromosomal regions previously linked to QTLs contributing to femoral neck and related phenotypes. PMID:18282130

  2. A microsatellite-based linkage map of salt tolerant tilapia (Oreochromis mossambicus x Oreochromis spp.) and mapping of sex-determining loci

    PubMed Central

    2013-01-01

    Background Tilapia is the common name for a group of cichlid fishes and is one of the most important aquacultured freshwater food fish. Mozambique tilapia and its hybrids, including red tilapia are main representatives of salt tolerant tilapias. A linkage map is an essential framework for mapping QTL for important traits, positional cloning of genes and understanding of genome evolution. Results We constructed a consensus linkage map of Mozambique tilapia and red tilapia using 95 individuals from two F1 families and 401 microsatellites including 282 EST-derived markers. In addition, we conducted comparative mapping and searched for sex-determining loci on the whole genome. These 401 microsatellites were assigned to 22 linkage groups. The map spanned 1067.6 cM with an average inter-marker distance of 3.3 cM. Comparative mapping between tilapia and stickleback, medaka, pufferfish and zebrafish revealed clear homologous relationships between chromosomes from different species. We found evidence for the fusion of two sets of two independent chromosomes forming two new chromosome pairs, leading to a reduction of 24 chromosome pairs in their ancestor to 22 pairs in tilapias. The XY sex determination locus in Mozambique tilapia was mapped on LG1, and verified in five families containing 549 individuals. The major XY sex determination locus in red tilapia was located on LG22, and verified in two families containing 275 individuals. Conclusions A first-generation linkage map of salt tolerant tilapia was constructed using 401 microsatellites. Two separate fusions of two sets of two independent chromosomes may lead to a reduction of 24 chromosome pairs in their ancestor to 22 pairs in tilapias. The XY sex-determining loci from Mozambique tilapia and red tilapia were mapped on LG1 and LG22, respectively. This map provides a useful resource for QTL mapping for important traits and comparative genome studies. The DNA markers linked to the sex-determining loci could be used in the selection of YY males for breeding all-male populations of salt tolerant tilapia, as well as in studies on mechanisms of sex determination in fish. PMID:23356773

  3. An Expressed Sequence Tag (EST)-enriched genetic map of turbot (Scophthalmus maximus): a useful framework for comparative genomics across model and farmed teleosts

    PubMed Central

    2012-01-01

    Background The turbot (Scophthalmus maximus) is a relevant species in European aquaculture. The small turbot genome provides a source for genomics strategies to use in order to understand the genetic basis of productive traits, particularly those related to sex, growth and pathogen resistance. Genetic maps represent essential genomic screening tools allowing to localize quantitative trait loci (QTL) and to identify candidate genes through comparative mapping. This information is the backbone to develop marker-assisted selection (MAS) programs in aquaculture. Expressed sequenced tag (EST) resources have largely increased in turbot, thus supplying numerous type I markers suitable for extending the previous linkage map, which was mostly based on anonymous loci. The aim of this study was to construct a higher-resolution turbot genetic map using EST-linked markers, which will turn out to be useful for comparative mapping studies. Results A consensus gene-enriched genetic map of the turbot was constructed using 463 SNP and microsatellite markers in nine reference families. This map contains 438 markers, 180 EST-linked, clustered at 24 linkage groups. Linkage and comparative genomics evidences suggested additional linkage group fusions toward the consolidation of turbot map according to karyotype information. The linkage map showed a total length of 1402.7 cM with low average intermarker distance (3.7 cM; ~2 Mb). A global 1.6:1 female-to-male recombination frequency (RF) ratio was observed, although largely variable among linkage groups and chromosome regions. Comparative sequence analysis revealed large macrosyntenic patterns against model teleost genomes, significant hits decreasing from stickleback (54%) to zebrafish (20%). Comparative mapping supported particular chromosome rearrangements within Acanthopterygii and aided to assign unallocated markers to specific turbot linkage groups. Conclusions The new gene-enriched high-resolution turbot map represents a useful genomic tool for QTL identification, positional cloning strategies, and future genome assembling. This map showed large synteny conservation against model teleost genomes. Comparative genomics and data mining from landmarks will provide straightforward access to candidate genes, which will be the basis for genetic breeding programs and evolutionary studies in this species. PMID:22747677

  4. Development and first use of a novel cylindrical ball bearing phantom for 9-DOF geometric calibrations of flat panel imaging devices used in image-guided ion beam therapy

    NASA Astrophysics Data System (ADS)

    Zechner, A.; Stock, M.; Kellner, D.; Ziegler, I.; Keuschnigg, P.; Huber, P.; Mayer, U.; Sedlmayer, F.; Deutschmann, H.; Steininger, P.

    2016-11-01

    Image guidance during highly conformal radiotherapy requires accurate geometric calibration of the moving components of the imager. Due to limited manufacturing accuracy and gravity-induced flex, an x-ray imager’s deviation from the nominal geometrical definition has to be corrected for. For this purpose a ball bearing phantom applicable for nine degrees of freedom (9-DOF) calibration of a novel cone-beam computed tomography (CBCT) scanner was designed and validated. In order to ensure accurate automated marker detection, as many uniformly distributed markers as possible should be used with a minimum projected inter-marker distance of 10 mm. Three different marker distributions on the phantom cylinder surface were simulated. First, a fixed number of markers are selected and their coordinates are randomly generated. Second, the quasi-random method is represented by setting a constraint on the marker distances in the projections. The third approach generates the ball coordinates helically based on the Golden ratio, ϕ. Projection images of the phantom incorporating the CBCT scanner’s geometry were simulated and analysed with respect to uniform distribution and intra-marker distance. Based on the evaluations a phantom prototype was manufactured and validated by a series of flexmap calibration measurements and analyses. The simulation with randomly distributed markers as well as the quasi-random approach showed an insufficient uniformity of the distribution over the detector area. The best compromise between uniform distribution and a high packing fraction of balls is provided by the Golden section approach. A prototype was manufactured accordingly. The phantom was validated for 9-DOF geometric calibrations of the CBCT scanner with independently moveable source and detector arms. A novel flexmap calibration phantom intended for 9-DOF was developed. The ball bearing distribution based on the Golden section was found to be highly advantageous. The phantom showed satisfying results for calibrations of the CBCT scanner and provides the basis for further flexmap correction and reconstruction developments.

  5. Development and first use of a novel cylindrical ball bearing phantom for 9-DOF geometric calibrations of flat panel imaging devices used in image-guided ion beam therapy.

    PubMed

    Zechner, A; Stock, M; Kellner, D; Ziegler, I; Keuschnigg, P; Huber, P; Mayer, U; Sedlmayer, F; Deutschmann, H; Steininger, P

    2016-11-21

    Image guidance during highly conformal radiotherapy requires accurate geometric calibration of the moving components of the imager. Due to limited manufacturing accuracy and gravity-induced flex, an x-ray imager's deviation from the nominal geometrical definition has to be corrected for. For this purpose a ball bearing phantom applicable for nine degrees of freedom (9-DOF) calibration of a novel cone-beam computed tomography (CBCT) scanner was designed and validated. In order to ensure accurate automated marker detection, as many uniformly distributed markers as possible should be used with a minimum projected inter-marker distance of 10 mm. Three different marker distributions on the phantom cylinder surface were simulated. First, a fixed number of markers are selected and their coordinates are randomly generated. Second, the quasi-random method is represented by setting a constraint on the marker distances in the projections. The third approach generates the ball coordinates helically based on the Golden ratio, ϕ. Projection images of the phantom incorporating the CBCT scanner's geometry were simulated and analysed with respect to uniform distribution and intra-marker distance. Based on the evaluations a phantom prototype was manufactured and validated by a series of flexmap calibration measurements and analyses. The simulation with randomly distributed markers as well as the quasi-random approach showed an insufficient uniformity of the distribution over the detector area. The best compromise between uniform distribution and a high packing fraction of balls is provided by the Golden section approach. A prototype was manufactured accordingly. The phantom was validated for 9-DOF geometric calibrations of the CBCT scanner with independently moveable source and detector arms. A novel flexmap calibration phantom intended for 9-DOF was developed. The ball bearing distribution based on the Golden section was found to be highly advantageous. The phantom showed satisfying results for calibrations of the CBCT scanner and provides the basis for further flexmap correction and reconstruction developments.

  6. Digital stereophotogrammetry based on circular markers and zooming cameras: evaluation of a method for 3D analysis of small motions in orthopaedic research

    PubMed Central

    2011-01-01

    Background Orthopaedic research projects focusing on small displacements in a small measurement volume require a radiation free, three dimensional motion analysis system. A stereophotogrammetrical motion analysis system can track wireless, small, light-weight markers attached to the objects. Thereby the disturbance of the measured objects through the marker tracking can be kept at minimum. The purpose of this study was to develop and evaluate a non-position fixed compact motion analysis system configured for a small measurement volume and able to zoom while tracking small round flat markers in respect to a fiducial marker which was used for the camera pose estimation. Methods The system consisted of two web cameras and the fiducial marker placed in front of them. The markers to track were black circles on a white background. The algorithm to detect a centre of the projected circle on the image plane was described and applied. In order to evaluate the accuracy (mean measurement error) and precision (standard deviation of the measurement error) of the optical measurement system, two experiments were performed: 1) inter-marker distance measurement and 2) marker displacement measurement. Results The first experiment of the 10 mm distances measurement showed a total accuracy of 0.0086 mm and precision of ± 0.1002 mm. In the second experiment, translations from 0.5 mm to 5 mm were measured with total accuracy of 0.0038 mm and precision of ± 0.0461 mm. The rotations of 2.25° amount were measured with the entire accuracy of 0.058° and the precision was of ± 0.172°. Conclusions The description of the non-proprietary measurement device with very good levels of accuracy and precision may provide opportunities for new, cost effective applications of stereophotogrammetrical analysis in musculoskeletal research projects, focusing on kinematics of small displacements in a small measurement volume. PMID:21284867

  7. Stability, Visibility, and Histologic Analysis of a New Implanted Fiducial for Use as a Kilovoltage Radiographic or Radioactive Marker for Patient Positioning and Monitoring in Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neustadter, David, E-mail: david.n@navotek.co; Tune, Michal; Zaretsky, Asaph

    Purpose: To analyze the stability, visibility, and histology of a novel implantable soft-tissue marker (nonradioactive and radioactive) implanted in dog prostate and rabbit liver. Methods and Materials: A total of 34 nonradioactive and 35 radioactive markers were implanted in 1 dog and 16 rabbits. Stability was assessed by measuring intermarker distance (IMD) variation relative to IMDs at implantation. The IMDs were measured weekly for 4 months in the dog and biweekly for 2-4 weeks in the rabbits. Ultrasound and X-ray imaging were performed on all subjects. Computed tomography and MRI were performed on the dog. Histologic analysis was performed onmore » the rabbits after 2 or 4 months. Results: A total of 139 measurements had a mean ({+-} SD) absolute IMD variation of 1.1 {+-} 1.1 mm. These IMD variations are consistent with those reported in the literature as due to random organ deformation. The markers were visible, identifiable, and induced minimal or no image artifacts in all tested imaging modalities. Histologic analysis revealed that all pathologic changes were highly localized and not expected to be clinically significant. Conclusions: The markers were stable from the time of implantation. The markers were found to be compatible with all common medical imaging modalities. The markers caused no significant histologic effects. With respect to marker stability, visibility, and histologic analysis these implanted fiducials are appropriate for soft-tissue target positioning in radiotherapy.« less

  8. [Travel time and distances to Norwegian out-of-hours casualty clinics].

    PubMed

    Raknes, Guttorm; Morken, Tone; Hunskår, Steinar

    2014-11-01

    Geographical factors have an impact on the utilisation of out-of-hours services. In this study we have investigated the travel distance to out-of-hours casualty clinics in Norwegian municipalities in 2011 and the number of municipalities covered by the proposed recommendations for secondary on-call arrangements due to long distances. We estimated the average maximum travel times and distances in Norwegian municipalities using a postcode-based method. Separate analyses were performed for municipalities with a single, permanently located casualty clinic. Altogether 417 out of 430 municipalities were included. We present the median value of the maximum travel times and distances for the included municipalities. The median maximum average travel distance for the municipalities was 19 km. The median maximum average travel time was 22 minutes. In 40 of the municipalities (10 %) the median maximum average travel time exceeded 60 minutes, and in 97 municipalities (23 %) the median maximum average travel time exceeded 40 minutes. The population of these groups comprised 2 % and 5 % of the country's total population respectively. For municipalities with permanent emergency facilities(N = 316), the median average flight time 16 minutes and median average distance 13 km.. In many municipalities, the inhabitants have a long average journey to out-of-hours emergency health services, but seen as a whole, the inhabitants of these municipalities account for a very small proportion of the Norwegian population. The results indicate that the proposed recommendations for secondary on-call duty based on long distances apply to only a small number of inhabitants. The recommendations should therefore be adjusted and reformulated to become more relevant.

  9. Genome-wide generation and use of informative intron-spanning and intron-length polymorphism markers for high-throughput genetic analysis in rice

    PubMed Central

    Badoni, Saurabh; Das, Sweta; Sayal, Yogesh K.; Gopalakrishnan, S.; Singh, Ashok K.; Rao, Atmakuri R.; Agarwal, Pinky; Parida, Swarup K.; Tyagi, Akhilesh K.

    2016-01-01

    We developed genome-wide 84634 ISM (intron-spanning marker) and 16510 InDel-fragment length polymorphism-based ILP (intron-length polymorphism) markers from genes physically mapped on 12 rice chromosomes. These genic markers revealed much higher amplification-efficiency (80%) and polymorphic-potential (66%) among rice accessions even by a cost-effective agarose gel-based assay. A wider level of functional molecular diversity (17–79%) and well-defined precise admixed genetic structure was assayed by 3052 genome-wide markers in a structured population of indica, japonica, aromatic and wild rice. Six major grain weight QTLs (11.9–21.6% phenotypic variation explained) were mapped on five rice chromosomes of a high-density (inter-marker distance: 0.98 cM) genetic linkage map (IR 64 x Sonasal) anchored with 2785 known/candidate gene-derived ISM and ILP markers. The designing of multiple ISM and ILP markers (2 to 4 markers/gene) in an individual gene will broaden the user-preference to select suitable primer combination for efficient assaying of functional allelic variation/diversity and realistic estimation of differential gene expression profiles among rice accessions. The genomic information generated in our study is made publicly accessible through a user-friendly web-resource, “Oryza ISM-ILP marker” database. The known/candidate gene-derived ISM and ILP markers can be enormously deployed to identify functionally relevant trait-associated molecular tags by optimal-resource expenses, leading towards genomics-assisted crop improvement in rice. PMID:27032371

  10. Average geodesic distance of skeleton networks of Sierpinski tetrahedron

    NASA Astrophysics Data System (ADS)

    Yang, Jinjin; Wang, Songjing; Xi, Lifeng; Ye, Yongchao

    2018-04-01

    The average distance is concerned in the research of complex networks and is related to Wiener sum which is a topological invariant in chemical graph theory. In this paper, we study the skeleton networks of the Sierpinski tetrahedron, an important self-similar fractal, and obtain their asymptotic formula for average distances. To provide the formula, we develop some technique named finite patterns of integral of geodesic distance on self-similar measure for the Sierpinski tetrahedron.

  11. Mutually unbiased bases in six dimensions: The four most distant bases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raynal, Philippe; Lue Xin; Englert, Berthold-Georg

    2011-06-15

    We consider the average distance between four bases in six dimensions. The distance between two orthonormal bases vanishes when the bases are the same, and the distance reaches its maximal value of unity when the bases are unbiased. We perform a numerical search for the maximum average distance and find it to be strictly smaller than unity. This is strong evidence that no four mutually unbiased bases exist in six dimensions. We also provide a two-parameter family of three bases which, together with the canonical basis, reach the numerically found maximum of the average distance, and we conduct a detailedmore » study of the structure of the extremal set of bases.« less

  12. High-Resolution Maps of Mouse Reference Populations

    PubMed Central

    Simecek, Petr; Forejt, Jiri; Williams, Robert W.; Shiroishi, Toshihiko; Takada, Toyoyuki; Lu, Lu; Johnson, Thomas E.; Bennett, Beth; Deschepper, Christian F.; Scott-Boyer, Marie-Pier; Pardo-Manuel de Villena, Fernando; Churchill, Gary A.

    2017-01-01

    Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS/IbgTejJ, and C57BL/6J × A/J) and chromosome substitution strain panels (C57BL/6J-Chr#, C57BL/6J-Chr#, and C57BL/6J-Chr#). We genotyped all samples using the Affymetrix Mouse Diversity Array with an average intermarker spacing of 4.3 kb. The new genetic maps provide increased precision in the localization of recombination breakpoints compared to the previous maps. Although the strains were presumed to be fully inbred, we found residual heterozygosity in 40% of individual mice from five of the six panels. We also identified de novo deletions and duplications, in homozygous or heterozygous state, ranging in size from 21 kb to 8.4 Mb. Almost two-thirds (46 out of 76) of these deletions overlap exons of protein coding genes and may have phenotypic consequences. Twenty-nine putative gene conversions were identified in the chromosome substitution strains. We find that gene conversions are more likely to occur in regions where the homologous chromosomes are more similar. The raw genotyping data and genetic maps of these strain panels are available at http://churchill-lab.jax.org/website/MDA. PMID:28839117

  13. High-Resolution Maps of Mouse Reference Populations.

    PubMed

    Simecek, Petr; Forejt, Jiri; Williams, Robert W; Shiroishi, Toshihiko; Takada, Toyoyuki; Lu, Lu; Johnson, Thomas E; Bennett, Beth; Deschepper, Christian F; Scott-Boyer, Marie-Pier; Pardo-Manuel de Villena, Fernando; Churchill, Gary A

    2017-10-05

    Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS/IbgTejJ, and C57BL/6J × A/J) and chromosome substitution strain panels (C57BL/6J-Chr#, C57BL/6J-Chr#, and C57BL/6J-Chr#). We genotyped all samples using the Affymetrix Mouse Diversity Array with an average intermarker spacing of 4.3 kb. The new genetic maps provide increased precision in the localization of recombination breakpoints compared to the previous maps. Although the strains were presumed to be fully inbred, we found residual heterozygosity in 40% of individual mice from five of the six panels. We also identified de novo deletions and duplications, in homozygous or heterozygous state, ranging in size from 21 kb to 8.4 Mb. Almost two-thirds (46 out of 76) of these deletions overlap exons of protein coding genes and may have phenotypic consequences. Twenty-nine putative gene conversions were identified in the chromosome substitution strains. We find that gene conversions are more likely to occur in regions where the homologous chromosomes are more similar. The raw genotyping data and genetic maps of these strain panels are available at http://churchill-lab.jax.org/website/MDA. Copyright © 2017 Simecek et al.

  14. Automatic tracking of arbitrarily shaped implanted markers in kilovoltage projection images: A feasibility study

    PubMed Central

    Regmi, Rajesh; Lovelock, D. Michael; Hunt, Margie; Zhang, Pengpeng; Pham, Hai; Xiong, Jianping; Yorke, Ellen D.; Goodman, Karyn A.; Rimner, Andreas; Mostafavi, Hassan; Mageras, Gig S.

    2014-01-01

    Purpose: Certain types of commonly used fiducial markers take on irregular shapes upon implantation in soft tissue. This poses a challenge for methods that assume a predefined shape of markers when automatically tracking such markers in kilovoltage (kV) radiographs. The authors have developed a method of automatically tracking regularly and irregularly shaped markers using kV projection images and assessed its potential for detecting intrafractional target motion during rotational treatment. Methods: Template-based matching used a normalized cross-correlation with simplex minimization. Templates were created from computed tomography (CT) images for phantom studies and from end-expiration breath-hold planning CT for patient studies. The kV images were processed using a Sobel filter to enhance marker visibility. To correct for changes in intermarker relative positions between simulation and treatment that can introduce errors in automatic matching, marker offsets in three dimensions were manually determined from an approximately orthogonal pair of kV images. Two studies in anthropomorphic phantom were carried out, one using a gold cylindrical marker representing regular shape, another using a Visicoil marker representing irregular shape. Automatic matching of templates to cone beam CT (CBCT) projection images was performed to known marker positions in phantom. In patient data, automatic matching was compared to manual matching as an approximate ground truth. Positional discrepancy between automatic and manual matching of less than 2 mm was assumed as the criterion for successful tracking. Tracking success rates were examined in kV projection images from 22 CBCT scans of four pancreas, six gastroesophageal junction, and one lung cancer patients. Each patient had at least one irregularly shaped radiopaque marker implanted in or near the tumor. In addition, automatic tracking was tested in intrafraction kV images of three lung cancer patients with irregularly shaped markers during 11 volumetric modulated arc treatments. Purpose-built software developed at our institution was used to create marker templates and track the markers embedded in kV images. Results: Phantom studies showed mean ± standard deviation measurement uncertainty of automatic registration to be 0.14 ± 0.07 mm and 0.17 ± 0.08 mm for Visicoil and gold cylindrical markers, respectively. The mean success rate of automatic tracking with CBCT projections (11 frames per second, fps) of pancreas, gastroesophageal junction, and lung cancer patients was 100%, 99.1% (range 98%–100%), and 100%, respectively. With intrafraction images (approx. 0.2 fps) of lung cancer patients, the success rate was 98.2% (range 97%–100%), and 94.3% (range 93%–97%) using templates from 1.25 mm and 2.5 mm slice spacing CT scans, respectively. Correction of intermarker relative position was found to improve the success rate in two out of eight patients analyzed. Conclusions: The proposed method can track arbitrary marker shapes in kV images using templates generated from a breath-hold CT acquired at simulation. The studies indicate its feasibility for tracking tumor motion during rotational treatment. Investigation of the causes of misregistration suggests that its rate of incidence can be reduced with higher frequency of image acquisition, templates made from smaller CT slice spacing, and correction of changes in intermarker relative positions when they occur. PMID:24989384

  15. Automatic tracking of arbitrarily shaped implanted markers in kilovoltage projection images: A feasibility study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Regmi, Rajesh; Lovelock, D. Michael; Hunt, Margie

    Purpose: Certain types of commonly used fiducial markers take on irregular shapes upon implantation in soft tissue. This poses a challenge for methods that assume a predefined shape of markers when automatically tracking such markers in kilovoltage (kV) radiographs. The authors have developed a method of automatically tracking regularly and irregularly shaped markers using kV projection images and assessed its potential for detecting intrafractional target motion during rotational treatment. Methods: Template-based matching used a normalized cross-correlation with simplex minimization. Templates were created from computed tomography (CT) images for phantom studies and from end-expiration breath-hold planning CT for patient studies. Themore » kV images were processed using a Sobel filter to enhance marker visibility. To correct for changes in intermarker relative positions between simulation and treatment that can introduce errors in automatic matching, marker offsets in three dimensions were manually determined from an approximately orthogonal pair of kV images. Two studies in anthropomorphic phantom were carried out, one using a gold cylindrical marker representing regular shape, another using a Visicoil marker representing irregular shape. Automatic matching of templates to cone beam CT (CBCT) projection images was performed to known marker positions in phantom. In patient data, automatic matching was compared to manual matching as an approximate ground truth. Positional discrepancy between automatic and manual matching of less than 2 mm was assumed as the criterion for successful tracking. Tracking success rates were examined in kV projection images from 22 CBCT scans of four pancreas, six gastroesophageal junction, and one lung cancer patients. Each patient had at least one irregularly shaped radiopaque marker implanted in or near the tumor. In addition, automatic tracking was tested in intrafraction kV images of three lung cancer patients with irregularly shaped markers during 11 volumetric modulated arc treatments. Purpose-built software developed at our institution was used to create marker templates and track the markers embedded in kV images. Results: Phantom studies showed mean ± standard deviation measurement uncertainty of automatic registration to be 0.14 ± 0.07 mm and 0.17 ± 0.08 mm for Visicoil and gold cylindrical markers, respectively. The mean success rate of automatic tracking with CBCT projections (11 frames per second, fps) of pancreas, gastroesophageal junction, and lung cancer patients was 100%, 99.1% (range 98%–100%), and 100%, respectively. With intrafraction images (approx. 0.2 fps) of lung cancer patients, the success rate was 98.2% (range 97%–100%), and 94.3% (range 93%–97%) using templates from 1.25 mm and 2.5 mm slice spacing CT scans, respectively. Correction of intermarker relative position was found to improve the success rate in two out of eight patients analyzed. Conclusions: The proposed method can track arbitrary marker shapes in kV images using templates generated from a breath-hold CT acquired at simulation. The studies indicate its feasibility for tracking tumor motion during rotational treatment. Investigation of the causes of misregistration suggests that its rate of incidence can be reduced with higher frequency of image acquisition, templates made from smaller CT slice spacing, and correction of changes in intermarker relative positions when they occur.« less

  16. Method paper--distance and travel time to casualty clinics in Norway based on crowdsourced postcode coordinates: a comparison with other methods.

    PubMed

    Raknes, Guttorm; Hunskaar, Steinar

    2014-01-01

    We describe a method that uses crowdsourced postcode coordinates and Google maps to estimate average distance and travel time for inhabitants of a municipality to a casualty clinic in Norway. The new method was compared with methods based on population centroids, median distance and town hall location, and we used it to examine how distance affects the utilisation of out-of-hours primary care services. At short distances our method showed good correlation with mean travel time and distance. The utilisation of out-of-hours services correlated with postcode based distances similar to previous research. The results show that our method is a reliable and useful tool for estimating average travel distances and travel times.

  17. Thermal motion in proteins: Large effects on the time-averaged interaction energies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goethe, Martin, E-mail: martingoethe@ub.edu; Rubi, J. Miguel; Fita, Ignacio

    As a consequence of thermal motion, inter-atomic distances in proteins fluctuate strongly around their average values, and hence, also interaction energies (i.e. the pair-potentials evaluated at the fluctuating distances) are not constant in time but exhibit pronounced fluctuations. These fluctuations cause that time-averaged interaction energies do generally not coincide with the energy values obtained by evaluating the pair-potentials at the average distances. More precisely, time-averaged interaction energies behave typically smoother in terms of the average distance than the corresponding pair-potentials. This averaging effect is referred to as the thermal smoothing effect. Here, we estimate the strength of the thermal smoothingmore » effect on the Lennard-Jones pair-potential for globular proteins at ambient conditions using x-ray diffraction and simulation data of a representative set of proteins. For specific atom species, we find a significant smoothing effect where the time-averaged interaction energy of a single atom pair can differ by various tens of cal/mol from the Lennard-Jones potential at the average distance. Importantly, we observe a dependency of the effect on the local environment of the involved atoms. The effect is typically weaker for bulky backbone atoms in beta sheets than for side-chain atoms belonging to other secondary structure on the surface of the protein. The results of this work have important practical implications for protein software relying on free energy expressions. We show that the accuracy of free energy expressions can largely be increased by introducing environment specific Lennard-Jones parameters accounting for the fact that the typical thermal motion of protein atoms depends strongly on their local environment.« less

  18. Thermal motion in proteins: Large effects on the time-averaged interaction energies

    NASA Astrophysics Data System (ADS)

    Goethe, Martin; Fita, Ignacio; Rubi, J. Miguel

    2016-03-01

    As a consequence of thermal motion, inter-atomic distances in proteins fluctuate strongly around their average values, and hence, also interaction energies (i.e. the pair-potentials evaluated at the fluctuating distances) are not constant in time but exhibit pronounced fluctuations. These fluctuations cause that time-averaged interaction energies do generally not coincide with the energy values obtained by evaluating the pair-potentials at the average distances. More precisely, time-averaged interaction energies behave typically smoother in terms of the average distance than the corresponding pair-potentials. This averaging effect is referred to as the thermal smoothing effect. Here, we estimate the strength of the thermal smoothing effect on the Lennard-Jones pair-potential for globular proteins at ambient conditions using x-ray diffraction and simulation data of a representative set of proteins. For specific atom species, we find a significant smoothing effect where the time-averaged interaction energy of a single atom pair can differ by various tens of cal/mol from the Lennard-Jones potential at the average distance. Importantly, we observe a dependency of the effect on the local environment of the involved atoms. The effect is typically weaker for bulky backbone atoms in beta sheets than for side-chain atoms belonging to other secondary structure on the surface of the protein. The results of this work have important practical implications for protein software relying on free energy expressions. We show that the accuracy of free energy expressions can largely be increased by introducing environment specific Lennard-Jones parameters accounting for the fact that the typical thermal motion of protein atoms depends strongly on their local environment.

  19. Cosmological ensemble and directional averages of observables

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonvin, Camille; Clarkson, Chris; Durrer, Ruth

    We show that at second order, ensemble averages of observables and directional averages do not commute due to gravitational lensing—observing the same thing in many directions over the sky is not the same as taking an ensemble average. In principle this non-commutativity is significant for a variety of quantities that we often use as observables and can lead to a bias in parameter estimation. We derive the relation between the ensemble average and the directional average of an observable, at second order in perturbation theory. We discuss the relevance of these two types of averages for making predictions of cosmologicalmore » observables, focusing on observables related to distances and magnitudes. In particular, we show that the ensemble average of the distance in a given observed direction is increased by gravitational lensing, whereas the directional average of the distance is decreased. For a generic observable, there exists a particular function of the observable that is not affected by second-order lensing perturbations. We also show that standard areas have an advantage over standard rulers, and we discuss the subtleties involved in averaging in the case of supernova observations.« less

  20. Match-play activity profile in elite women's rugby union players.

    PubMed

    Suarez-Arrones, Luis; Portillo, Javier; Pareja-Blanco, Fernando; Sáez de Villareal, Eduardo; Sánchez-Medina, Luis; Munguía-Izquierdo, Diego

    2014-02-01

    The aim of this study was to provide an objective description of the locomotive activities and exercise intensity undergone during the course of an international-level match of female rugby union. Eight players were analyzed using global positioning system tracking technology. The total distance covered by the players during the whole match was 5,820 ± 512 m. The backs covered significantly more distance than the forwards (6,356 ± 144 vs. 5,498 ± 412 m, respectively). Over this distance, 42.7% (2,487 ± 391 m) was spent standing or walking, 35% jogging (2,037 ± 315 m), 9.7% running at low intensity (566 ± 115 m), 9.5% at medium intensity (553 ± 190 m), 1.8% at high intensity (105 ± 74 m), and 1.2% sprinting (73 ± 107 m). There were significant differences in the distance covered by forwards and backs in certain speed zones. Analysis of the relative distance traveled over successive 10-minute period of match play revealed that the greatest distances were covered during the first (725 ± 53 m) and the last (702 ± 79 m) 10-minute period of the match. The average number of sprints, the average maximum distance of sprinting, the average minimum distance of sprinting, and the average sprint distance during the game were 4.7 ± 3.9 sprints, 20.6 ± 10.5 m, 5.8 ± 0.9 -m, and 12.0 ± 3.8 m, respectively. There were substantial differences between forwards and backs. Backs covered greater total distance, distance in certain speed zones, and sprinting performance. The players spent 46.9 ± 28.9% of match time between 91 and 100% of maximum heart rate and experienced a large number of impacts (accelerometer data and expressed as g forces) during the game. These findings offer important information to design better training strategies and physical fitness testing adapted to the specific demands of female rugby union.

  1. Dynamics of Polarons in Organic Conjugated Polymers with Side Radicals.

    PubMed

    Liu, J J; Wei, Z J; Zhang, Y L; Meng, Y; Di, B

    2017-03-16

    Based on the one-dimensional tight-binding Su-Schrieffer-Heeger (SSH) model, and using the molecular dynamics method, we discuss the dynamics of electron and hole polarons propagating along a polymer chain, as a function of the distance between side radicals and the magnitude of the transfer integrals between the main chain and the side radicals. We first discuss the average velocities of electron and hole polarons as a function of the distance between side radicals. It is found that the average velocities of the electron polarons remain almost unchanged, while the average velocities of hole polarons decrease significantly when the radical distance is comparable to the polaron width. Second, we have found that the average velocities of electron polarons decrease with increasing transfer integral, but the average velocities of hole polarons increase. These results may provide a theoretical basis for understanding carriers transport properties in polymers chain with side radicals.

  2. A comparison of sonography and radiography student scores in a cadaver anatomy class before and after the implementation of synchronous distance education.

    PubMed

    Bagley, Jennifer Elaine; Randall, K; Anderson, M P

    2015-02-01

    Distance education is a solution to expand medical imaging education to students who might not otherwise be able to obtain the education. It can be a mechanism to reduce the health care worker shortage in underserved areas. In some cases, distance education may be a disruptive technology, and might lower student performance. This study compares student scores in a cadaver anatomy course in the four cohorts preceding the implementation of distance education to the first three cohorts that took the course using a multiple campus design. The means and medians of the lecture exam average, the laboratory component score, and the final course score of the nondistance education cohorts were compared with those of the distance education cohorts using nonparametric statistical analysis. Scores in an anatomy course were compared by campus placement among the distance education cohorts, and the independent effect of distance education on the laboratory component, lecture examination average, and final course scores, while controlling for cumulative grade point average and site (originating/distant), was assessed. Students receiving the course in a nondistance education environment scored higher in the anatomy course than the students who took the course in a distance education environment. Students on the distant campus scored lower than students on the originating site. Distance education technology creates new opportunities for learning, but can be a disruptive technology. Programs seeking to implement distance education into their curriculum should do so with knowledge of the advantages and disadvantages.

  3. Rise and Shock: Optimal Defibrillator Placement in a High-rise Building.

    PubMed

    Chan, Timothy C Y

    2017-01-01

    Out-of-hospital cardiac arrests (OHCA) in high-rise buildings experience lower survival and longer delays until paramedic arrival. Use of publicly accessible automated external defibrillators (AED) can improve survival, but "vertical" placement has not been studied. We aim to determine whether elevator-based or lobby-based AED placement results in shorter vertical distance travelled ("response distance") to OHCAs in a high-rise building. We developed a model of a single-elevator, n-floor high-rise building. We calculated and compared the average distance from AED to floor of arrest for the two AED locations. We modeled OHCA occurrences using floor-specific Poisson processes, the risk of OHCA on the ground floor (λ 1 ) and the risk on any above-ground floor (λ). The elevator was modeled with an override function enabling direct travel to the target floor. The elevator location upon override was modeled as a discrete uniform random variable. Calculations used the laws of probability. Elevator-based AED placement had shorter average response distance if the number of floors (n) in the building exceeded three quarters of the ratio of ground-floor OHCA risk to above-ground floor risk (λ 1 /λ) plus one half (n ≥ 3λ 1 /4λ + 0.5). Otherwise, a lobby-based AED had shorter average response distance. If OHCA risk on each floor was equal, an elevator-based AED had shorter average response distance. Elevator-based AEDs travel less vertical distance to OHCAs in tall buildings or those with uniform vertical risk, while lobby-based AEDs travel less vertical distance in buildings with substantial lobby, underground, and nearby street-level traffic and OHCA risk.

  4. A comparison of sonography and radiography student scores in a cadaver anatomy class before and after the implementation of synchronous distance education

    PubMed Central

    Randall, K; Anderson, MP

    2015-01-01

    Distance education is a solution to expand medical imaging education to students who might not otherwise be able to obtain the education. It can be a mechanism to reduce the health care worker shortage in underserved areas. In some cases, distance education may be a disruptive technology, and might lower student performance. This study compares student scores in a cadaver anatomy course in the four cohorts preceding the implementation of distance education to the first three cohorts that took the course using a multiple campus design. The means and medians of the lecture exam average, the laboratory component score, and the final course score of the nondistance education cohorts were compared with those of the distance education cohorts using nonparametric statistical analysis. Scores in an anatomy course were compared by campus placement among the distance education cohorts, and the independent effect of distance education on the laboratory component, lecture examination average, and final course scores, while controlling for cumulative grade point average and site (originating/distant), was assessed. Students receiving the course in a nondistance education environment scored higher in the anatomy course than the students who took the course in a distance education environment. Students on the distant campus scored lower than students on the originating site. Distance education technology creates new opportunities for learning, but can be a disruptive technology. Programs seeking to implement distance education into their curriculum should do so with knowledge of the advantages and disadvantages. PMID:27433237

  5. Determining average yarding distance.

    Treesearch

    Roger H. Twito; Charles N. Mann

    1979-01-01

    Emphasis on environmental and esthetic quality in timber harvesting has brought about increased use of complex boundaries of cutting units and a consequent need for a rapid and accurate method of determining the average yarding distance and area of these units. These values, needed for evaluation of road and landing locations in planning timber harvests, are easily and...

  6. Lessons from a geospatial analysis of depot medroxyprogesterone acetate sales by licensed chemical sellers in Ghana.

    PubMed

    Shelus, Victoria; Lebetkin, Elena; Keyes, Emily; Mensah, Stephen; Dzasi, Kafui

    2015-08-01

    To map access to depot medroxyprogesterone acetate (DMPA) from licensed chemical sellers (LCS); to estimate the proportion of women of reproductive age in areas with access; and to examine affordability and variability of costs. A geospatial analysis was conducted using data collected from 298 women who purchased DMPA from 49 geocoded LCS shops in the Amansie West and Ejisu-Juabeng districts of Ghana from June 4 to August 31, 2012. The women reported on cost and average distance traveled to purchase DMPA. In Amansie West, 21.1% of all women of reproductive age lived within average walking distance and 80.4% lived within average driving distance of an LCS. In Ejisu-Juabeng, 41.9% and 60.1% of women lived within average walking and driving distance, respectively. Distribution of affordability varied across each district. Access to LCS shops is high, and training LCS to administer DMPA would increase access to family planning in Ghana, with associated time and cost savings. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  7. Estimating the population size and colony boundary of subterranean termites by using the density functions of directionally averaged capture probability.

    PubMed

    Su, Nan-Yao; Lee, Sang-Hee

    2008-04-01

    Marked termites were released in a linear-connected foraging arena, and the spatial heterogeneity of their capture probabilities was averaged for both directions at distance r from release point to obtain a symmetrical distribution, from which the density function of directionally averaged capture probability P(x) was derived. We hypothesized that as marked termites move into the population and given sufficient time, the directionally averaged capture probability may reach an equilibrium P(e) over the distance r and thus satisfy the equal mixing assumption of the mark-recapture protocol. The equilibrium capture probability P(e) was used to estimate the population size N. The hypothesis was tested in a 50-m extended foraging arena to simulate the distance factor of field colonies of subterranean termites. Over the 42-d test period, the density functions of directionally averaged capture probability P(x) exhibited four phases: exponential decline phase, linear decline phase, equilibrium phase, and postequilibrium phase. The equilibrium capture probability P(e), derived as the intercept of the linear regression during the equilibrium phase, correctly projected N estimates that were not significantly different from the known number of workers in the arena. Because the area beneath the probability density function is a constant (50% in this study), preequilibrium regression parameters and P(e) were used to estimate the population boundary distance 1, which is the distance between the release point and the boundary beyond which the population is absent.

  8. Ureter tracking and segmentation in CT urography (CTU) using COMPASS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hadjiiski, Lubomir, E-mail: lhadjisk@umich.edu; Zick, David; Chan, Heang-Ping

    2014-12-15

    Purpose: The authors are developing a computerized system for automated segmentation of ureters in CTU, referred to as combined model-guided path-finding analysis and segmentation system (COMPASS). Ureter segmentation is a critical component for computer-aided diagnosis of ureter cancer. Methods: COMPASS consists of three stages: (1) rule-based adaptive thresholding and region growing, (2) path-finding and propagation, and (3) edge profile extraction and feature analysis. With institutional review board approval, 79 CTU scans performed with intravenous (IV) contrast material enhancement were collected retrospectively from 79 patient files. One hundred twenty-four ureters were selected from the 79 CTU volumes. On average, the uretersmore » spanned 283 computed tomography slices (range: 116–399, median: 301). More than half of the ureters contained malignant or benign lesions and some had ureter wall thickening due to malignancy. A starting point for each of the 124 ureters was identified manually to initialize the tracking by COMPASS. In addition, the centerline of each ureter was manually marked and used as reference standard for evaluation of tracking performance. The performance of COMPASS was quantitatively assessed by estimating the percentage of the length that was successfully tracked and segmented for each ureter and by estimating the average distance and the average maximum distance between the computer and the manually tracked centerlines. Results: Of the 124 ureters, 120 (97%) were segmented completely (100%), 121 (98%) were segmented through at least 70%, and 123 (99%) were segmented through at least 50% of its length. In comparison, using our previous method, 85 (69%) ureters were segmented completely (100%), 100 (81%) were segmented through at least 70%, and 107 (86%) were segmented at least 50% of its length. With COMPASS, the average distance between the computer and the manually generated centerlines is 0.54 mm, and the average maximum distance is 2.02 mm. With our previous method, the average distance between the centerlines was 0.80 mm, and the average maximum distance was 3.38 mm. The improvements in the ureteral tracking length and both distance measures were statistically significant (p < 0.0001). Conclusions: COMPASS improved significantly the ureter tracking, including regions across ureter lesions, wall thickening, and the narrowing of the lumen.« less

  9. Study of Anthropometric Measurements of the Anterior Ethmoidal Artery using Three-dimensional Scanning on 300 Patients

    PubMed Central

    Bortoli, Vinicius Tomadon; Martins, Rafael Ferri; Negri, Krystal Calmeto

    2017-01-01

    Introduction The anterior ethmoidal artery (AEA) is one of the main arteries that supply both the nasal mucosa and the ethmoid sinuses. The AEA shows variability regarding its distance from adjacent structures. Several studies have developed techniques to identify the AEA. Objective This study aimed to compare the measurements from the AEA to the ethmoid bulla and to the frontal beak by using computed tomography of the face, while identifying their intraindividual and interindividual variations. Methods We analyzed 300 CT scans of the face performed at the CT scan Center at Hospital. The average age of subjects was 36 ± 15.1 years (range 4–84). Results We found that the average distance from the AEA to the ethmoid bulla was 17.2 ± 1.8 mm and the distance from the AEA to the frontal beak was 15.1 ± 2.2 mm. Regarding the average distance from the AEA to the frontal beak (AEA-frontal beak), there was a difference between the right and left sides, with the former being 0.4 mm higher on average than the latter. Among the age groups, there was a significant difference of distances between the AEA and the ethmoid bulla (AEA-ethmoid bulla), which were shorter in the ≤ 12 years group. There was a positive and significant correlation between both measurements analyzed, with low values (high) of AEA-ethmoid bulla distance corresponding to low values (high) of AEA-frontal beak distance. Conclusion The measurements obtained adds anatomical knowledge that can serve as a parameter in frontal and ethmoid sinus surgery. PMID:28382116

  10. Tree-average distances on certain phylogenetic networks have their weights uniquely determined.

    PubMed

    Willson, Stephen J

    2012-01-01

    A phylogenetic network N has vertices corresponding to species and arcs corresponding to direct genetic inheritance from the species at the tail to the species at the head. Measurements of DNA are often made on species in the leaf set, and one seeks to infer properties of the network, possibly including the graph itself. In the case of phylogenetic trees, distances between extant species are frequently used to infer the phylogenetic trees by methods such as neighbor-joining. This paper proposes a tree-average distance for networks more general than trees. The notion requires a weight on each arc measuring the genetic change along the arc. For each displayed tree the distance between two leaves is the sum of the weights along the path joining them. At a hybrid vertex, each character is inherited from one of its parents. We will assume that for each hybrid there is a probability that the inheritance of a character is from a specified parent. Assume that the inheritance events at different hybrids are independent. Then for each displayed tree there will be a probability that the inheritance of a given character follows the tree; this probability may be interpreted as the probability of the tree. The tree-average distance between the leaves is defined to be the expected value of their distance in the displayed trees. For a class of rooted networks that includes rooted trees, it is shown that the weights and the probabilities at each hybrid vertex can be calculated given the network and the tree-average distances between the leaves. Hence these weights and probabilities are uniquely determined. The hypotheses on the networks include that hybrid vertices have indegree exactly 2 and that vertices that are not leaves have a tree-child.

  11. The metabolic power and energetic demands of elite Gaelic football match play.

    PubMed

    Malone, Shane; Solan, Barry; Collins, Kieran; Doran, Dominic

    2017-05-01

    Metabolic power has not yet been investigated within elite Gaelic football. The aim of the current investigation was to compare the metabolic power demands between positional groups and examine the temporal profile of elite Gaelic football match play. Global positional satellite system (GPS) data were collected from 50 elite Gaelic football players from 4 inter-county teams during 35 elite competitive matches over a three season period. A total of 351 complete match samples were obtained for final analysis. Players were categorized based on positional groups; full-back, half-back, midfield, half-forward and full-forward. Instantaneous raw velocity data was obtained from the GPS and exported to a customized spreadsheet which provided estimations of both speed based, derived metabolic power and energy expenditure variables (total distance, high speed distance, average metabolic power, high power distance and total energy expenditure). Match mean distance was 9222±1588 m, reflective of an average metabolic power of 9.5-12.5 W·kg-1, with an average energy expenditure of 58-70 Kj·kg-1 depending on position. There were significant differences between positional groups for both speed-based and metabolic power indices. Midfielders covered more total and high-speed distance, as well as greater average and overall energy expenditure compared to other positions (P<0.001). A reduction in total, high-speed, and high-power distance, as well as average metabolic power throughout the match (P<0.001) was observed. Positional differences exist for both metabolic power and traditional running based variables. The middle three positions (midfield, half-back and half-forward) possess greater activity profiles when compared to other positional groups. The reduction in metabolic power and traditional running based variables are comparable across match play. The current study demonstrates that metabolic power may contribute to our understanding of Gaelic football match-play.

  12. Concentrations of volatile organic compounds, carbon monoxide, carbon dioxide and particulate matter in buses on highways in Taiwan

    NASA Astrophysics Data System (ADS)

    Hsu, Der-Jen; Huang, Hsiao-Lin

    2009-12-01

    Although airborne pollutants in urban buses have been studied in many cities globally, long-distance buses running mainly on highways have not been addressed in this regard. This study investigates the levels of volatile organic compounds (VOCs), carbon monoxide (CO), carbon dioxide (CO 2) and particulate matter (PM) in the long-distance buses in Taiwan. Analytical results indicate that pollutants levels in long-distance buses are generally lower than those in urban buses. This finding is attributable to the driving speed and patterns of long-distance buses, as well as the meteorological and geographical features of the highway surroundings. The levels of benzene, toluene, ethylbenzene and xylene (BTEX) found in bus cabins exceed the proposed indoor VOC guidelines for aromatic compounds, and are likely attributable to the interior trim in the cabins. The overall average CO level is 2.3 ppm, with higher average level on local streets (2.9 ppm) than on highways (2.2 ppm). The average CO 2 level is 1493 ppm, which is higher than the guideline for non-industrial occupied settings. The average PM level in this study is lower than those in urban buses and IAQ guidelines set by Taiwan EPA. However, the average PM 10 and PM 2.5 is higher than the level set by WHO. Besides the probable causes mentioned above, fewer passenger movements and less particle re-suspension from bus floor might also cause the lower PM levels. Measurements of particle size distribution reveal that more than 75% of particles are in submicron and smaller sizes. These particles may come from the infiltration from the outdoor air. This study concludes that air exchange rates in long-distance buses should be increased in order to reduce CO 2 levels. Future research on long-distance buses should focus on the emission of VOCs from brand new buses, and the sources of submicron particles in bus cabins.

  13. Cognitive distance, absorptive capacity and group rationality: a simulation study.

    PubMed

    Curşeu, Petru Lucian; Krehel, Oleh; Evers, Joep H M; Muntean, Adrian

    2014-01-01

    We report the results of a simulation study in which we explore the joint effect of group absorptive capacity (as the average individual rationality of the group members) and cognitive distance (as the distance between the most rational group member and the rest of the group) on the emergence of collective rationality in groups. We start from empirical results reported in the literature on group rationality as collective group level competence and use data on real-life groups of four and five to validate a mathematical model. We then use this mathematical model to predict group level scores from a variety of possible group configurations (varying both in cognitive distance and average individual rationality). Our results show that both group competence and cognitive distance are necessary conditions for emergent group rationality. Group configurations, in which the groups become more rational than the most rational group member, are groups scoring low on cognitive distance and scoring high on absorptive capacity.

  14. Cognitive Distance, Absorptive Capacity and Group Rationality: A Simulation Study

    PubMed Central

    Curşeu, Petru Lucian; Krehel, Oleh; Evers, Joep H. M.; Muntean, Adrian

    2014-01-01

    We report the results of a simulation study in which we explore the joint effect of group absorptive capacity (as the average individual rationality of the group members) and cognitive distance (as the distance between the most rational group member and the rest of the group) on the emergence of collective rationality in groups. We start from empirical results reported in the literature on group rationality as collective group level competence and use data on real-life groups of four and five to validate a mathematical model. We then use this mathematical model to predict group level scores from a variety of possible group configurations (varying both in cognitive distance and average individual rationality). Our results show that both group competence and cognitive distance are necessary conditions for emergent group rationality. Group configurations, in which the groups become more rational than the most rational group member, are groups scoring low on cognitive distance and scoring high on absorptive capacity. PMID:25314132

  15. Impact of distance education on academic performance in a pharmaceutical care course

    PubMed Central

    Bem, Tamires; Carneiro, Mára Lucia Fernandes; de Castro, Mauro Silveira

    2017-01-01

    The objective of this study was to compare the performance of pharmacy students from a Pharmaceutical Care course, taught in both distance education (DE) and campus-based formats using active methodologies. For two semesters, students (n = 82) taking the course studied half the subject in the distance education format and half in person. Questionnaires were applied at the beginning of the semester aimed to outline the demographic profile of the students. Their grade in the course was evaluated to determine their performance. The Module 1 (Information on Medication) average on the campus-based was 7.1225 and on DE was 7.5519, (p = 0.117). The Module 2 (Pharmaceutical Services) average on the campus-based was 7.1595 and on distance education was 7.7025, (p = 0.027*). There was a difference in learning outcomes in the Pharmaceutical Care Course between face-to-face and distant education. Therefore, the student performance was better in the distance education module, indicating distance education can be satisfactorily used in Pharmacy Programs. PMID:28384362

  16. Heterogeneity Measurement Based on Distance Measure for Polarimetric SAR Data

    NASA Astrophysics Data System (ADS)

    Xing, Xiaoli; Chen, Qihao; Liu, Xiuguo

    2018-04-01

    To effectively test the scene heterogeneity for polarimetric synthetic aperture radar (PolSAR) data, in this paper, the distance measure is introduced by utilizing the similarity between the sample and pixels. Moreover, given the influence of the distribution and modeling texture, the K distance measure is deduced according to the Wishart distance measure. Specifically, the average of the pixels in the local window replaces the class center coherency or covariance matrix. The Wishart and K distance measure are calculated between the average matrix and the pixels. Then, the ratio of the standard deviation to the mean is established for the Wishart and K distance measure, and the two features are defined and applied to reflect the complexity of the scene. The proposed heterogeneity measure is proceeded by integrating the two features using the Pauli basis. The experiments conducted on the single-look and multilook PolSAR data demonstrate the effectiveness of the proposed method for the detection of the scene heterogeneity.

  17. The average magnetic field draping and consistent plasma properties of the Venus magnetotail

    NASA Technical Reports Server (NTRS)

    Mccomas, D. J.; Spence, H. E.; Russell, C. T.; Saunders, M. A.

    1986-01-01

    The detailed average draping pattern of the magnetic field in the deep Venus magnetotail is examined. The variability of the data ordered by spatial location is studied, and the groundwork is laid for developing a coordinate system which measured locations with respect to the tail structures. The reconstruction of the tail in the presence of flapping using a new technique is shown, and the average variations in the field components are examined, including the average field vectors, cross-tail current density distribution, and J x B forces as functions of location across the tail. The average downtail velocity is derived as a function of distance, and a simple model based on the field variations is defined from which the average plasma acceleration is obtained as a function of distance, density, and temperature.

  18. On the development and global oscillations of cometary ionospheres

    NASA Technical Reports Server (NTRS)

    Houpis, H. L. F.; Mendis, D. A.

    1981-01-01

    Representing the cometary ionosphere by a single fluid model characterized by an average ionization time scale, both the ionosphere's development as a comet approaches the sun and its response to sudden changes in solar wind conditions are investigated. Three different nuclear sizes (small, average, very large) and three different modes of energy addition to the atmosphere (adiabatic, isothermal, suprathermal) are considered. It is found that the crucial parameter determining both the nature and the size of the ionosphere is the average ionization time scale within the ionosphere. Two different scales are identified. It is noted that the ionosphere can also be characterized by the relative sizes of three different scale lengths: the neutral standoff distance from the nucleus, the ion standoff distance from the nucleus, and the nuclear distance at which the ions and the neutrals decouple collisionally.

  19. Sleeping distance in wild wolf packs

    USGS Publications Warehouse

    Knick, S.T.; Mech, L.D.

    1980-01-01

    Sleeping distances were observed among members of 13 wild wolf (Canis lupus) packs and 11 pairs in northeastern Minnesota to determine if the distances correlated with pack size and composition. The study utilized aerial radio-tracking and observation during winter. Pack size and number of adults per pack were inversely related to pack average sleeping distance and variability. No correlation between sleeping distance and microclimate was observed. Possible relationships between social bonding and our results are discussed.

  20. Oppugning the assumptions of spatial averaging of segment and joint orientations.

    PubMed

    Pierrynowski, Michael Raymond; Ball, Kevin Arthur

    2009-02-09

    Movement scientists frequently calculate "arithmetic averages" when examining body segment or joint orientations. Such calculations appear routinely, yet are fundamentally flawed. Three-dimensional orientation data are computed as matrices, yet three-ordered Euler/Cardan/Bryant angle parameters are frequently used for interpretation. These parameters are not geometrically independent; thus, the conventional process of averaging each parameter is incorrect. The process of arithmetic averaging also assumes that the distances between data are linear (Euclidean); however, for the orientation data these distances are geodesically curved (Riemannian). Therefore we question (oppugn) whether use of the conventional averaging approach is an appropriate statistic. Fortunately, exact methods of averaging orientation data have been developed which both circumvent the parameterization issue, and explicitly acknowledge the Euclidean or Riemannian distance measures. The details of these matrix-based averaging methods are presented and their theoretical advantages discussed. The Euclidian and Riemannian approaches offer appealing advantages over the conventional technique. With respect to practical biomechanical relevancy, examinations of simulated data suggest that for sets of orientation data possessing characteristics of low dispersion, an isotropic distribution, and less than 30 degrees second and third angle parameters, discrepancies with the conventional approach are less than 1.1 degrees . However, beyond these limits, arithmetic averaging can have substantive non-linear inaccuracies in all three parameterized angles. The biomechanics community is encouraged to recognize that limitations exist with the use of the conventional method of averaging orientations. Investigations requiring more robust spatial averaging over a broader range of orientations may benefit from the use of matrix-based Euclidean or Riemannian calculations.

  1. A hybrid correlation analysis with application to imaging genetics

    NASA Astrophysics Data System (ADS)

    Hu, Wenxing; Fang, Jian; Calhoun, Vince D.; Wang, Yu-Ping

    2018-03-01

    Investigating the association between brain regions and genes continues to be a challenging topic in imaging genetics. Current brain region of interest (ROI)-gene association studies normally reduce data dimension by averaging the value of voxels in each ROI. This averaging may lead to a loss of information due to the existence of functional sub-regions. Pearson correlation is widely used for association analysis. However, it only detects linear correlation whereas nonlinear correlation may exist among ROIs. In this work, we introduced distance correlation to ROI-gene association analysis, which can detect both linear and nonlinear correlations and overcome the limitation of averaging operations by taking advantage of the information at each voxel. Nevertheless, distance correlation usually has a much lower value than Pearson correlation. To address this problem, we proposed a hybrid correlation analysis approach, by applying canonical correlation analysis (CCA) to the distance covariance matrix instead of directly computing distance correlation. Incorporating CCA into distance correlation approach may be more suitable for complex disease study because it can detect highly associated pairs of ROI and gene groups, and may improve the distance correlation level and statistical power. In addition, we developed a novel nonlinear CCA, called distance kernel CCA, which seeks the optimal combination of features with the most significant dependence. This approach was applied to imaging genetic data from the Philadelphia Neurodevelopmental Cohort (PNC). Experiments showed that our hybrid approach produced more consistent results than conventional CCA across resampling and both the correlation and statistical significance were increased compared to distance correlation analysis. Further gene enrichment analysis and region of interest (ROI) analysis confirmed the associations of the identified genes with brain ROIs. Therefore, our approach provides a powerful tool for finding the correlation between brain imaging and genomic data.

  2. On the safety assessment of human exposure in the proximity of cellular communications base-station antennas at 900, 1800 and 2170 MHz.

    PubMed

    Martínez-Búrdalo, M; Martín, A; Anguiano, M; Villar, R

    2005-09-07

    In this work, the procedures for safety assessment in the close proximity of cellular communications base-station antennas at three different frequencies (900, 1800 and 2170 MHz) are analysed. For each operating frequency, we have obtained and compared the distances to the antenna from the exposure places where electromagnetic fields are below reference levels and the distances where the specific absorption rate (SAR) values in an exposed person are below the basic restrictions, according to the European safety guidelines. A high-resolution human body model has been located, in front of each base-station antenna as a worst case, at different distances, to compute whole body averaged SAR and maximum 10 g averaged SAR inside the exposed body. The finite-difference time-domain method has been used for both electromagnetic fields and SAR calculations. This paper shows that, for antenna-body distances in the near zone of the antenna, the fact that averaged field values be below the reference levels could, at certain frequencies, not guarantee guidelines compliance based on basic restrictions.

  3. Oral sampling methods are associated with differences in immune marker concentrations.

    PubMed

    Fakhry, Carole; Qeadan, Fares; Gilman, Robert H; Yori, Pablo; Kosek, Margaret; Patterson, Nicole; Eisele, David W; Gourin, Christine G; Chitguppi, Chandala; Marks, Morgan; Gravitt, Patti

    2018-06-01

    To determine whether the concentration and distribution of immune markers in paired oral samples were similar. Clinical research. Cross-sectional study. Paired saliva and oral secretions (OS) samples were collected. The concentration of immune markers was estimated using Luminex multiplex assay (Thermo Fisher Scientific, Waltham, MA). For each sample, the concentration of respective immune markers was normalized to total protein present and log-transformed. Median concentrations of immune markers were compared between both types of samples. Intermarker correlation in each sampling method and across sampling methods was evaluated. There were 90 study participants. Concentrations of immune markers in saliva samples were significantly different from concentrations in OS samples. Oral secretions samples showed higher concentrations of immunoregulatory markers, whereas the saliva samples contained proinflammatory markers in higher concentration. The immune marker profile in saliva samples is distinct from the immune marker profile in paired OS samples. 2b. Laryngoscope, 128:E214-E221, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  4. The effect of age on the racing speed of Thoroughbred racehorses

    PubMed Central

    TAKAHASHI, Toshiyuki

    2015-01-01

    ABSTRACT The running performance of Thoroughbred racehorses has been reported to peak when they are between 4 and 5 years old. However, changes in their racing speed by month or season have not been reported. The purposes of this study were to reveal the average racing speed of Thoroughbreds, and observe changes in their average speed with age. The surveyed races were flat races on turf and dirt tracks with firm or standard track conditions held by the Japan Racing Association from January 1st, 2002 to December 31st, 2010. The racing speed of each horse was calculated by dividing the race distance (m) by the horse’s final time (sec). Average speeds per month for each age and distance condition were calculated for each gender group when there were 30 or more starters per month for each age and distance condition for each gender group. The common characteristic change for all conditions was an average speed increase up until the first half of the age of 4 years old. The effect of increased carry weight on average speed was small, and average speed increased with the growth of the horse. After the latter half of the age of 4 years old, the horses’ average speed remained almost constant, with little variation. It is speculated that decreases in the weight carried; and the retirement of less well performing horses; are responsible for the maintenance of average speed. PMID:26170760

  5. Average luminosity distance in inhomogeneous universes

    NASA Astrophysics Data System (ADS)

    Kostov, Valentin Angelov

    Using numerical ray tracing, the paper studies how the average distance modulus in an inhomogeneous universe differs from its homogeneous counterpart. The averaging is over all directions from a fixed observer not over all possible observers (cosmic), thus it is more directly applicable to our observations. Unlike previous studies, the averaging is exact, non-perturbative, an includes all possible non-linear effects. The inhomogeneous universes are represented by Sweese-cheese models containing random and simple cubic lattices of mass- compensated voids. The Earth observer is in the homogeneous cheese which has an Einstein - de Sitter metric. For the first time, the averaging is widened to include the supernovas inside the voids by assuming the probability for supernova emission from any comoving volume is proportional to the rest mass in it. For voids aligned in a certain direction, there is a cumulative gravitational lensing correction to the distance modulus that increases with redshift. That correction is present even for small voids and depends on the density contrast of the voids, not on their radius. Averaging over all directions destroys the cumulative correction even in a non-randomized simple cubic lattice of voids. Despite the well known argument for photon flux conservation, the average distance modulus correction at low redshifts is not zero due to the peculiar velocities. A formula for the maximum possible average correction as a function of redshift is derived and shown to be in excellent agreement with the numerical results. The formula applies to voids of any size that: (1) have approximately constant densities in their interior and walls, (2) are not in a deep nonlinear regime. The actual average correction calculated in random and simple cubic void lattices is severely damped below the predicted maximum. That is traced to cancelations between the corrections coming from the fronts and backs of different voids at the same redshift from the observer. The calculated correction at low redshifts allows one to readily predict the redshift at which the averaged fluctuation in the Hubble diagram is below a required precision and suggests a method to extract the background Hubble constant from low redshift data without the need to correct for peculiar velocities.

  6. A virtual pebble game to ensemble average graph rigidity.

    PubMed

    González, Luis C; Wang, Hui; Livesay, Dennis R; Jacobs, Donald J

    2015-01-01

    The body-bar Pebble Game (PG) algorithm is commonly used to calculate network rigidity properties in proteins and polymeric materials. To account for fluctuating interactions such as hydrogen bonds, an ensemble of constraint topologies are sampled, and average network properties are obtained by averaging PG characterizations. At a simpler level of sophistication, Maxwell constraint counting (MCC) provides a rigorous lower bound for the number of internal degrees of freedom (DOF) within a body-bar network, and it is commonly employed to test if a molecular structure is globally under-constrained or over-constrained. MCC is a mean field approximation (MFA) that ignores spatial fluctuations of distance constraints by replacing the actual molecular structure by an effective medium that has distance constraints globally distributed with perfect uniform density. The Virtual Pebble Game (VPG) algorithm is a MFA that retains spatial inhomogeneity in the density of constraints on all length scales. Network fluctuations due to distance constraints that may be present or absent based on binary random dynamic variables are suppressed by replacing all possible constraint topology realizations with the probabilities that distance constraints are present. The VPG algorithm is isomorphic to the PG algorithm, where integers for counting "pebbles" placed on vertices or edges in the PG map to real numbers representing the probability to find a pebble. In the VPG, edges are assigned pebble capacities, and pebble movements become a continuous flow of probability within the network. Comparisons between the VPG and average PG results over a test set of proteins and disordered lattices demonstrate the VPG quantitatively estimates the ensemble average PG results well. The VPG performs about 20% faster than one PG, and it provides a pragmatic alternative to averaging PG rigidity characteristics over an ensemble of constraint topologies. The utility of the VPG falls in between the most accurate but slowest method of ensemble averaging over hundreds to thousands of independent PG runs, and the fastest but least accurate MCC.

  7. Cognitive Style and Self-Efficacy: Predicting Student Success in Online Distance Education

    ERIC Educational Resources Information Center

    DeTure, Monica

    2004-01-01

    This study was designed to identify those learner attributes that may be used to predict student success (in terms of grade point average) in a Web-based distance education setting. Students enrolled in six Web-based, general education distance education courses at a community college were asked to complete the Group Embedded Figures Test for…

  8. Functional connectivity and structural covariance between regions of interest can be measured more accurately using multivariate distance correlation.

    PubMed

    Geerligs, Linda; Cam-Can; Henson, Richard N

    2016-07-15

    Studies of brain-wide functional connectivity or structural covariance typically use measures like the Pearson correlation coefficient, applied to data that have been averaged across voxels within regions of interest (ROIs). However, averaging across voxels may result in biased connectivity estimates when there is inhomogeneity within those ROIs, e.g., sub-regions that exhibit different patterns of functional connectivity or structural covariance. Here, we propose a new measure based on "distance correlation"; a test of multivariate dependence of high dimensional vectors, which allows for both linear and non-linear dependencies. We used simulations to show how distance correlation out-performs Pearson correlation in the face of inhomogeneous ROIs. To evaluate this new measure on real data, we use resting-state fMRI scans and T1 structural scans from 2 sessions on each of 214 participants from the Cambridge Centre for Ageing & Neuroscience (Cam-CAN) project. Pearson correlation and distance correlation showed similar average connectivity patterns, for both functional connectivity and structural covariance. Nevertheless, distance correlation was shown to be 1) more reliable across sessions, 2) more similar across participants, and 3) more robust to different sets of ROIs. Moreover, we found that the similarity between functional connectivity and structural covariance estimates was higher for distance correlation compared to Pearson correlation. We also explored the relative effects of different preprocessing options and motion artefacts on functional connectivity. Because distance correlation is easy to implement and fast to compute, it is a promising alternative to Pearson correlations for investigating ROI-based brain-wide connectivity patterns, for functional as well as structural data. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Identifying Canadian Freshwater Fishes through DNA Barcodes

    PubMed Central

    Hubert, Nicolas; Hanner, Robert; Holm, Erling; Mandrak, Nicholas E.; Taylor, Eric; Burridge, Mary; Watkinson, Douglas; Dumont, Pierre; Curry, Allen; Bentzen, Paul; Zhang, Junbin; April, Julien; Bernatchez, Louis

    2008-01-01

    Background DNA barcoding aims to provide an efficient method for species-level identifications using an array of species specific molecular tags derived from the 5′ region of the mitochondrial cytochrome c oxidase I (COI) gene. The efficiency of the method hinges on the degree of sequence divergence among species and species-level identifications are relatively straightforward when the average genetic distance among individuals within a species does not exceed the average genetic distance between sister species. Fishes constitute a highly diverse group of vertebrates that exhibit deep phenotypic changes during development. In this context, the identification of fish species is challenging and DNA barcoding provide new perspectives in ecology and systematics of fishes. Here we examined the degree to which DNA barcoding discriminate freshwater fish species from the well-known Canadian fauna, which currently encompasses nearly 200 species, some which are of high economic value like salmons and sturgeons. Methodology/Principal Findings We bi-directionally sequenced the standard 652 bp “barcode” region of COI for 1360 individuals belonging to 190 of the 203 Canadian freshwater fish species (95%). Most species were represented by multiple individuals (7.6 on average), the majority of which were retained as voucher specimens. The average genetic distance was 27 fold higher between species than within species, as K2P distance estimates averaged 8.3% among congeners and only 0.3% among concpecifics. However, shared polymorphism between sister-species was detected in 15 species (8% of the cases). The distribution of K2P distance between individuals and species overlapped and identifications were only possible to species group using DNA barcodes in these cases. Conversely, deep hidden genetic divergence was revealed within two species, suggesting the presence of cryptic species. Conclusions/Significance The present study evidenced that freshwater fish species can be efficiently identified through the use of DNA barcoding, especially the species complex of small-sized species, and that the present COI library can be used for subsequent applications in ecology and systematics. PMID:22423312

  10. The Effect of Light Level and Small Pupils on Presbyopic Reading Performance.

    PubMed

    Xu, Renfeng; Gil, Daniel; Dibas, Mohammed; Hare, William; Bradley, Arthur

    2016-10-01

    To examine the impact of small pupils and light levels on reading performance of distance-corrected presbyopes. To determine whether small pupils would enable presbyopes to read at near even at low light levels. To establish the lower range of text luminances, we quantified the space-averaged luminance of text in nine different artificially lit interior environments, and examined the impact of the text characters on space-averaged luminance of electronic and printed displays. Distance and near reading speeds of 20 presbyopes (ages 40-60 years) were measured while viewing through artificial pupils (diameters 1-4.5 mm), natural pupils, or with a multifocal contact lens. Space-averaged text luminance levels varied from 0.14 to 140 cd/m2 (including the range of measured environmental text luminances). Adding black text to a white computer display or paper reduces luminance by approximately 15% to 31%, and the lowest encountered environmental text luminance was approximately 2 to 3 cd/m2. For both distance and near reading performance, the 2- to 3-mm small pupil yielded the best overall reading acuity for space-averaged text light levels ≥ 2 cd/m2. The 2- to 3-mm artificial pupils and the multifocal contact lenses both enabled maximum or near-maximum reading speeds for 0.5 logMAR characters at distance and near, but with natural pupils, reading speeds were significantly reduced at near. Although photon noise at low luminance reduces the visual benefits of small pupils, the benefits of 2- to 3-mm artificial pupils are sufficient to enable >80% of distance-corrected presbyopes to read proficiently at near, even at the lowest text luminances found in interior environments.

  11. Evaluation of proximity of mandibular molars and second premolar to inferior alveolar nerve canal among central Indians: A cone-beam computed tomographic retrospective study.

    PubMed

    Hiremath, Hemalatha; Agarwal, Rolly; Hiremath, Vishwanath; Phulambrikar, Tushar

    2016-01-01

    A study was done to assess the average distances of root apices of mandibular first molar, second molar, and second premolar to inferior alveolar nerve canal (IANC), among males and females in central India. High-resolution full-volume cone-beam computed tomography (CBCT) scans were obtained from the radiology database at the Sri Aurobindo College of Dentistry, Indore. After scrutinizing the database, CBCT of 40 males and 40 females that conformed to the inclusion and exclusion criteria were selected for the study. All the data were analyzed using SPSS, Version 16. Descriptive statistics of the variables and measurements are presented using Students t-test (paired and unpaired), and correlation between age was tabled by Karl Pearson's correlation coefficient method. For the second premolar, the average distance to the IANC was 0.88-13.03 mm for males and 0.00-5.49 mm for females. The average distance of IANC to the mesial root apex of first molar was 1.46-13.23 mm for males and 0.93-8.03 mm for females. For the second molar, the average distance was 1.31-14.71 mm for males and 0.00-6.91 mm for females (values on left side were shorter as compared to right side). In the overall population, only second molar exhibited significant difference in the distance from root apex to IANC when compared bilaterally. In addition to gender differences, age-related differences were found to be significant for the first molar on left side and second molar on the right side of the population (P< 0.05).

  12. Finding the average speed of a light-emitting toy car with a smartphone light sensor

    NASA Astrophysics Data System (ADS)

    Kapucu, Serkan

    2017-07-01

    This study aims to demonstrate how the average speed of a light-emitting toy car may be determined using a smartphone’s light sensor. The freely available Android smartphone application, ‘AndroSensor’, was used for the experiment. The classroom experiment combines complementary physics knowledge of optics and kinematics to find the average speed of a moving object. The speed of the toy car is found by determining the distance between the light-emitting toy car and the smartphone, and the time taken to travel these distances. To ensure that the average speed of the toy car calculated with the help of the AndroSensor was correct, the average speed was also calculated by analyzing video-recordings of the toy car. The resulting speeds found with these different methods were in good agreement with each other. Hence, it can be concluded that reliable measurements of the average speed of light-emitting objects can be determined with the help of the light sensor of an Android smartphone.

  13. Evolutionary mixed games in structured populations: Cooperation and the benefits of heterogeneity

    NASA Astrophysics Data System (ADS)

    Amaral, Marco A.; Wardil, Lucas; Perc, Matjaž; da Silva, Jafferson K. L.

    2016-04-01

    Evolutionary games on networks traditionally involve the same game at each interaction. Here we depart from this assumption by considering mixed games, where the game played at each interaction is drawn uniformly at random from a set of two different games. While in well-mixed populations the random mixture of the two games is always equivalent to the average single game, in structured populations this is not always the case. We show that the outcome is, in fact, strongly dependent on the distance of separation of the two games in the parameter space. Effectively, this distance introduces payoff heterogeneity, and the average game is returned only if the heterogeneity is small. For higher levels of heterogeneity the distance to the average game grows, which often involves the promotion of cooperation. The presented results support preceding research that highlights the favorable role of heterogeneity regardless of its origin, and they also emphasize the importance of the population structure in amplifying facilitators of cooperation.

  14. Evolutionary mixed games in structured populations: Cooperation and the benefits of heterogeneity.

    PubMed

    Amaral, Marco A; Wardil, Lucas; Perc, Matjaž; da Silva, Jafferson K L

    2016-04-01

    Evolutionary games on networks traditionally involve the same game at each interaction. Here we depart from this assumption by considering mixed games, where the game played at each interaction is drawn uniformly at random from a set of two different games. While in well-mixed populations the random mixture of the two games is always equivalent to the average single game, in structured populations this is not always the case. We show that the outcome is, in fact, strongly dependent on the distance of separation of the two games in the parameter space. Effectively, this distance introduces payoff heterogeneity, and the average game is returned only if the heterogeneity is small. For higher levels of heterogeneity the distance to the average game grows, which often involves the promotion of cooperation. The presented results support preceding research that highlights the favorable role of heterogeneity regardless of its origin, and they also emphasize the importance of the population structure in amplifying facilitators of cooperation.

  15. Mercury accumulation in transplanted Hypogymnia physodes lichens downwind of Wisconsin chlor-alkali plant

    USGS Publications Warehouse

    Makholm, M.M.; Bennett, J.P.

    1998-01-01

    Emissions of mercury from a chlor-alkali plant in central Wisconsin have raised concern about possible effects on biota in the area. Samples of the lichen Hypogymnia physodes, which no longer grows in the area, were transplanted from a site in northeastern Wisconsin and positioned on plastic stands at varying distances up to 1250 m from the plant and sampled for Hg quarterly for one year to test the hypothesis that Hg would be taken up by the lichens and would decline with distance. Average tissue concentrations were elevated when first sampled at three months and continued to increase at the nearest sites until the study ended after one year. Average concentrations after a year of exposure ranged from 4418 ppb at 250 m from the plant to 403 ppb at 1250 m from the plant. The decrease over distance followed a negative exponential pattern. Background concentrations at a control site in northern Wisconsin averaged 155 ppb.

  16. Ground-motion prediction equations for the average horizontal component of PGA, PGV, and 5%-damped PSA at spectral periods between 0.01 s and 10.0 s

    USGS Publications Warehouse

    Boore, D.M.; Atkinson, G.M.

    2008-01-01

    This paper contains ground-motion prediction equations (GMPEs) for average horizontal-component ground motions as a function of earthquake magnitude, distance from source to site, local average shear-wave velocity, and fault type. Our equations are for peak ground acceleration (PGA), peak ground velocity (PGV), and 5%-damped pseudo-absolute-acceleration spectra (PSA) at periods between 0.01 s and 10 s. They were derived by empirical regression of an extensive strong-motion database compiled by the 'PEER NGA' (Pacific Earthquake Engineering Research Center's Next Generation Attenuation) project. For periods less than 1 s, the analysis used 1,574 records from 58 mainshocks in the distance range from 0 km to 400 km (the number of available data decreased as period increased). The primary predictor variables are moment magnitude (M), closest horizontal distance to the surface projection of the fault plane (RJB), and the time-averaged shear-wave velocity from the surface to 30 m (VS30). The equations are applicable for M=5-8, RJB<200 km, and VS30= 180-1300 m/s. ?? 2008, Earthquake Engineering Research Institute.

  17. Does player unavailability affect football teams' match physical outputs? A two-season study of the UEFA champions league.

    PubMed

    Windt, Johann; Ekstrand, Jan; Khan, Karim M; McCall, Alan; Zumbo, Bruno D

    2018-05-01

    Player unavailability negatively affects team performance in elite football. However, whether player unavailability and its concomitant performance decrement is mediated by any changes in teams' match physical outputs is unknown. We examined whether the number of players injured (i.e. unavailable for match selection) was associated with any changes in teams' physical outputs. Prospective cohort study. Between-team variation was calculated by correlating average team availability with average physical outputs. Within-team variation was quantified using linear mixed modelling, using physical outputs - total distance, sprint count (efforts over 20km/h), and percent of distance covered at high speeds (>14km/h) - as outcome variables, and player unavailability as the independent variable of interest. To control for other factors that may influence match physical outputs, stage (group stage/knockout), venue (home/away), score differential, ball possession (%), team ranking (UEFA Club Coefficient), and average team age were all included as covariates. Teams' average player unavailability was positively associated with the average number of sprints they performed in matches across two seasons. Multilevel models similarly demonstrated that having 4 unavailable players was associated with 20.8 more sprints during matches in 2015/2016, and with an estimated 0.60-0.77% increase in the proportion of total distance run above 14km/h in both seasons. Player unavailability had a possibly positive and likely positive association with total match distances in the two respective seasons. Having more players injured and unavailable for match selection was associated with an increase in teams' match physical outputs. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  18. Launch pad lightning protection effectiveness

    NASA Technical Reports Server (NTRS)

    Stahmann, James R.

    1991-01-01

    Using the striking distance theory that lightning leaders will strike the nearest grounded point on their last jump to earth corresponding to the striking distance, the probability of striking a point on a structure in the presence of other points can be estimated. The lightning strokes are divided into deciles having an average peak current and striking distance. The striking distances are used as radii from the points to generate windows of approach through which the leader must pass to reach a designated point. The projections of the windows on a horizontal plane as they are rotated through all possible angles of approach define an area that can be multiplied by the decile stroke density to arrive at the probability of strokes with the window average striking distance. The sum of all decile probabilities gives the cumulative probability for all strokes. The techniques can be applied to NASA-Kennedy launch pad structures to estimate the lightning protection effectiveness for the crane, gaseous oxygen vent arm, and other points. Streamers from sharp points on the structure provide protection for surfaces having large radii of curvature. The effects of nearby structures can also be estimated.

  19. Distance Measurements In X-Ray Pictures

    NASA Astrophysics Data System (ADS)

    Forsgren, Per-Ola

    1987-10-01

    In this paper, a measurement method for the distance between binary objects will be presented. It has been developed for a specific purpose, the evaluation of rheumatic disease, but should be useful also in other applications. It is based on a distance map in the area between binary objects. A skeleton is extracted from the distance map by searching for local maxima. The distance measure is based on the average of skelton points in a defined measurement area. An objective criterion for selection of measurement points on the skeleton is proposed. Preliminary results indicate that good repeatability is attained.

  20. 41 CFR 302-4.704 - Must we require a minimum driving distance per day?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Federal Travel Regulation System RELOCATION ALLOWANCES PERMANENT CHANGE OF STATION (PCS) ALLOWANCES FOR... driving distance not less than an average of 300 miles per day. However, an exception to the daily minimum... reasons acceptable to you. ...

  1. The attenuation of Fourier amplitudes for rock sites in eastern North America

    USGS Publications Warehouse

    Atkinson, Gail M.; Boore, David M.

    2014-01-01

    We develop an empirical model of the decay of Fourier amplitudes for earthquakes of M 3–6 recorded on rock sites in eastern North America and discuss its implications for source parameters. Attenuation at distances from 10 to 500 km may be adequately described using a bilinear model with a geometric spreading of 1/R1.3 to a transition distance of 50 km, with a geometric spreading of 1/R0.5 at greater distances. For low frequencies and distances less than 50 km, the effective geometric spreading given by the model is perturbed using a frequency‐ and hypocentral depth‐dependent factor defined in such a way as to increase amplitudes at lower frequencies near the epicenter but leave the 1 km source amplitudes unchanged. The associated anelastic attenuation is determined for each event, with an average value being given by a regional quality factor of Q=525f 0.45. This model provides a match, on average, between the known seismic moment of events and the inferred low‐frequency spectral amplitudes at R=1  km (obtained by correcting for the attenuation model). The inferred Brune stress parameters from the high‐frequency source terms are about 600 bars (60 MPa), on average, for events of M>4.5.

  2. A high-resolution map of the Nile tilapia genome: a resource for studying cichlids and other percomorphs

    PubMed Central

    2012-01-01

    Background The Nile tilapia (Oreochromis niloticus) is the second most farmed fish species worldwide. It is also an important model for studies of fish physiology, particularly because of its broad tolerance to an array of environments. It is a good model to study evolutionary mechanisms in vertebrates, because of its close relationship to haplochromine cichlids, which have undergone rapid speciation in East Africa. The existing genomic resources for Nile tilapia include a genetic map, BAC end sequences and ESTs, but comparative genome analysis and maps of quantitative trait loci (QTL) are still limited. Results We have constructed a high-resolution radiation hybrid (RH) panel for the Nile tilapia and genotyped 1358 markers consisting of 850 genes, 82 markers corresponding to BAC end sequences, 154 microsatellites and 272 single nucleotide polymorphisms (SNPs). From these, 1296 markers could be associated in 81 RH groups, while 62 were not linked. The total size of the RH map is 34,084 cR3500 and 937,310 kb. It covers 88% of the entire genome with an estimated inter-marker distance of 742 Kb. Mapping of microsatellites enabled integration to the genetic map. We have merged LG8 and LG24 into a single linkage group, and confirmed that LG16-LG21 are also merged. The orientation and association of RH groups to each chromosome and LG was confirmed by chromosomal in situ hybridizations (FISH) of 55 BACs. Fifty RH groups were localized on the 22 chromosomes while 31 remained small orphan groups. Synteny relationships were determined between Nile tilapia, stickleback, medaka and pufferfish. Conclusion The RH map and associated FISH map provide a valuable gene-ordered resource for gene mapping and QTL studies. All genetic linkage groups with their corresponding RH groups now have a corresponding chromosome which can be identified in the karyotype. Placement of conserved segments indicated that multiple inter-chromosomal rearrangements have occurred between Nile tilapia and the other model fishes. These maps represent a valuable resource for organizing the forthcoming genome sequence of Nile tilapia, and provide a foundation for evolutionary studies of East African cichlid fishes. PMID:22672252

  3. Open star clusters in the Milky Way. Comparison of photometric and trigonometric distance scales based on Gaia TGAS data

    NASA Astrophysics Data System (ADS)

    Kovaleva, Dana A.; Piskunov, Anatoly E.; Kharchenko, Nina V.; Röser, Siegfried; Schilbach, Elena; Scholz, Ralf-Dieter; Reffert, Sabine; Yen, Steffi X.

    2017-10-01

    Context. The global survey of star clusters in the Milky Way (MWSC) is a comprehensive list of 3061 objects that provides, among other parameters, distances to clusters based on isochrone fitting. The Tycho-Gaia Astrometric Solution (TGAS) catalogue, which is a part of Gaia data release 1 (Gaia DR1), delivers accurate trigonometric parallax measurements for more than 2 million stars, including those in star clusters. Aims: We compare the open cluster photometric distance scale with the measurements given by the trigonometric parallaxes from TGAS to evaluate the consistency between these values. Methods: The average parallaxes of probable cluster members available in TGAS provide the trigonometric distance scale of open clusters, while the photometric scale is given by the distances published in the MWSC. Sixty-four clusters are suited for comparison as they have more than 16 probable members with parallax measurements in TGAS. We computed the average parallaxes of the probable members and compared these to the photometric parallaxes derived within the MWSC. Results: We find a good agreement between the trigonometric TGAS-based and the photometric MWSC-based distance scales of open clusters, which for distances less than 2.3 kpc coincide at a level of about 0.1 mas with no dependence on the distance. If at all, there is a slight systematic offset along the Galactic equator between 30° and 160° galactic longitude.

  4. Euclidean distance and Kolmogorov-Smirnov analyses of multi-day auditory event-related potentials: a longitudinal stability study

    NASA Astrophysics Data System (ADS)

    Durato, M. V.; Albano, A. M.; Rapp, P. E.; Nawang, S. A.

    2015-06-01

    The validity of ERPs as indices of stable neurophysiological traits is partially dependent on their stability over time. Previous studies on ERP stability, however, have reported diverse stability estimates despite using the same component scoring methods. This present study explores a novel approach in investigating the longitudinal stability of average ERPs—that is, by treating the ERP waveform as a time series and then applying Euclidean Distance and Kolmogorov-Smirnov analyses to evaluate the similarity or dissimilarity between the ERP time series of different sessions or run pairs. Nonlinear dynamical analysis show that in the absence of a change in medical condition, the average ERPs of healthy human adults are highly longitudinally stable—as evaluated by both the Euclidean distance and the Kolmogorov-Smirnov test.

  5. The Crossover Time as an Evaluation of Ocean Models Against Persistence

    NASA Astrophysics Data System (ADS)

    Phillipson, L. M.; Toumi, R.

    2018-01-01

    A new ocean evaluation metric, the crossover time, is defined as the time it takes for a numerical model to equal the performance of persistence. As an example, the average crossover time calculated using the Lagrangian separation distance (the distance between simulated trajectories and observed drifters) for the global MERCATOR ocean model analysis is found to be about 6 days. Conversely, the model forecast has an average crossover time longer than 6 days, suggesting limited skill in Lagrangian predictability by the current generation of global ocean models. The crossover time of the velocity error is less than 3 days, which is similar to the average decorrelation time of the observed drifters. The crossover time is a useful measure to quantify future ocean model improvements.

  6. Influence of voice focus on tongue movement in speech.

    PubMed

    Bressmann, Tim; de Boer, Gillian; Marino, Viviane Cristina de Castro; Fabron, Eliana Maria Gradim; Berti, Larissa Cristina

    2017-01-01

    The present study evaluated global aspects of lingual movement during sentence production with backward and forward voice focus. Nine female participants read a sentence with a variety of consonants in a normal condition and with backward and forward voice focus. Midsagittal tongue movement was recorded with ultrasound. Tongue height over time at an anterior, a central, and a posterior measurement angle was measured. The outcome measures were speech rate, cumulative distance travelled, and average movement speed of the tongue. There were no differences in speech rate between the different conditions. The cumulative distance travelled by the tongue and the average speed indicated that the posterior tongue travelled a smaller cumulative distance and at a slower speed in the forward focus condition. The central tongue moved a larger cumulative distance and at a higher speed in the backward focus condition. The study offers first insights on how tongue movement is affected by different voice focus settings and illustrates the plasticity of tongue movement in speech.

  7. The influence of footwear sole hardness on slip characteristics and slip-induced falls in young adults.

    PubMed

    Tsai, Yi-Ju; Powers, Christopher M

    2013-01-01

    Theoretically, a shoe that provides less friction could result in a greater slip distance and foot slipping velocity, thereby increasing the likelihood of falling. The purpose of this study was to investigate the effects of sole hardness on the probability of slip-induced falls. Forty young adults were randomized into a hard or a soft sole shoe group, and tested under both nonslippery and slippery floor conditions using a motion analysis system. The proportions of fall events in the hard- and soft-soled shoe groups were not statistically different. No differences were observed between shoe groups for average slip distance, peak and average heel velocity, and center of mass slipping velocity. A strong association was found between slip distance and the fall probability. Our results demonstrate that the probability of a slip-induced fall was not influenced by shoe hardness. Once a slip is induced, slip distance was the primary predictor of a slip-induced fall. © 2012 American Academy of Forensic Sciences.

  8. Improved distances and ages for stars common to TGAS and RAVE

    NASA Astrophysics Data System (ADS)

    McMillan, Paul J.; Kordopatis, Georges; Kunder, Andrea; Binney, James; Wojno, Jennifer; Zwitter, Tomaž; Steinmetz, Matthias; Bland-Hawthorn, Joss; Gibson, Brad K.; Gilmore, Gerard; Grebel, Eva K.; Helmi, Amina; Munari, Ulisse; Navarro, Julio F.; Parker, Quentin A.; Seabroke, George; Watson, Fred; Wyse, Rosemary F. G.

    2018-04-01

    We combine parallaxes from the first Gaia data release with the spectrophotometric distance estimation framework for stars in the fifth RAVE survey data release. The combined distance estimates are more accurate than either determination in isolation - uncertainties are on average two times smaller than for RAVE-only distances (three times smaller for dwarfs), and 1.4 times smaller than TGAS parallax uncertainties (two times smaller for giants). We are also able to compare the estimates from spectrophotometry to those from Gaia, and use this to assess the reliability of both catalogues and improve our distance estimates. We find that the distances to the lowest log g stars are, on average, overestimated and caution that they may not be reliable. We also find that it is likely that the Gaia random uncertainties are smaller than the reported values. As a byproduct we derive ages for the RAVE stars, many with relative uncertainties less than 20 percent. These results for 219 566 RAVE sources have been made publicly available, and we encourage their use for studies that combine the radial velocities provided by RAVE with the proper motions provided by Gaia. A sample that we believe to be reliable can be found by taking only the stars with the flag notification `flag_any=0'.

  9. Improved distances and ages for stars common to TGAS and RAVE

    NASA Astrophysics Data System (ADS)

    McMillan, Paul J.; Kordopatis, Georges; Kunder, Andrea; Binney, James; Wojno, Jennifer; Zwitter, Tomaž; Steinmetz, Matthias; Bland-Hawthorn, Joss; Gibson, Brad K.; Gilmore, Gerard; Grebel, Eva K.; Helmi, Amina; Munari, Ulisse; Navarro, Julio F.; Parker, Quentin A.; Seabroke, George; Watson, Fred; Wyse, Rosemary F. G.

    2018-07-01

    We combine parallaxes from the first Gaia data release with the spectrophotometric distance estimation framework for stars in the fifth RAVE survey data release. The combined distance estimates are more accurate than either determination in isolation - uncertainties are on average two times smaller than for RAVE-only distances (three times smaller for dwarfs), and 1.4 times smaller than TGAS parallax uncertainties (two times smaller for giants). We are also able to compare the estimates from spectrophotometry to those from Gaia, and use this to assess the reliability of both catalogues and improve our distance estimates. We find that the distances to the lowest log g stars are, on average, overestimated and caution that they may not be reliable. We also find that it is likely that the Gaia random uncertainties are smaller than the reported values. As a by-product we derive ages for the RAVE stars, many with relative uncertainties less than 20 per cent. These results for 219 566 RAVE sources have been made publicly available, and we encourage their use for studies that combine the radial velocities provided by RAVE with the proper motions provided by Gaia. A sample that we believe to be reliable can be found by taking only the stars with the flag notification `flag_any=0'.

  10. Automatic lung nodule matching for the follow-up in temporal chest CT scans

    NASA Astrophysics Data System (ADS)

    Hong, Helen; Lee, Jeongjin; Shin, Yeong Gil

    2006-03-01

    We propose a fast and robust registration method for matching lung nodules of temporal chest CT scans. Our method is composed of four stages. First, the lungs are extracted from chest CT scans by the automatic segmentation method. Second, the gross translational mismatch is corrected by the optimal cube registration. This initial registration does not require extracting any anatomical landmarks. Third, initial alignment is step by step refined by the iterative surface registration. To evaluate the distance measure between surface boundary points, a 3D distance map is generated by the narrow-band distance propagation, which drives fast and robust convergence to the optimal location. Fourth, nodule correspondences are established by the pairs with the smallest Euclidean distances. The results of pulmonary nodule alignment of twenty patients are reported on a per-center-of mass point basis using the average Euclidean distance (AED) error between corresponding nodules of initial and follow-up scans. The average AED error of twenty patients is significantly reduced to 4.7mm from 30.0mm by our registration. Experimental results show that our registration method aligns the lung nodules much faster than the conventional ones using a distance measure. Accurate and fast result of our method would be more useful for the radiologist's evaluation of pulmonary nodules on chest CT scans.

  11. Crystal-structure analysis of four mineral samples of anhydrite, CaSO[subscript 4], using synchrotron high-resolution powder X-ray diffraction data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antao, Sytle M.

    2014-05-28

    The crystal structures of four samples of anhydrite, CaSO{sub 4}, were obtained by Rietveld refinements using synchrotron high-resolution powder X-ray diffraction (HRPXRD) data and space group Amma. As an example, for one sample of anhydrite from Hants County, Nova Scotia, the unit-cell parameters are a = 7.00032(2), b = 6.99234(1), c = 6.24097(1) {angstrom}, and V = 305.487(1) {angstrom}{sup 3} with a > b. The eight-coordinated Ca atom has an average distance of 2.4667(4) {angstrom}. The tetrahedral SO{sub 4} group has two independent S-O distances of 1.484(1) to O1 and 1.478(1) {angstrom} to O2 and an average distancemore » of 1.4810(5) {angstrom}. The three independent O-S-O angles [108.99(8) x 1, 110.38(3) x 4, 106.34(9){sup o} x 1; average [6] = 109.47(2){sup o}] and S-O distances indicate that the geometry of the SO{sub 4} group is quite distorted in anhydrite. The four anhydrite samples have structural trends where the a, b, and c unit-cell parameters increase linearly with increasing unit-cell volume, V, and their average and distances are nearly constant. The grand mean = 2.4660(2) {angstrom}, and grand mean = 1.4848(3) {angstrom}, the latter is longer than 1.480(1) {angstrom} in celestite, SrSO{sub 4}, as expected.« less

  12. A straightforward method to compute average stochastic oscillations from data samples.

    PubMed

    Júlvez, Jorge

    2015-10-19

    Many biological systems exhibit sustained stochastic oscillations in their steady state. Assessing these oscillations is usually a challenging task due to the potential variability of the amplitude and frequency of the oscillations over time. As a result of this variability, when several stochastic replications are averaged, the oscillations are flattened and can be overlooked. This can easily lead to the erroneous conclusion that the system reaches a constant steady state. This paper proposes a straightforward method to detect and asses stochastic oscillations. The basis of the method is in the use of polar coordinates for systems with two species, and cylindrical coordinates for systems with more than two species. By slightly modifying these coordinate systems, it is possible to compute the total angular distance run by the system and the average Euclidean distance to a reference point. This allows us to compute confidence intervals, both for the average angular speed and for the distance to a reference point, from a set of replications. The use of polar (or cylindrical) coordinates provides a new perspective of the system dynamics. The mean trajectory that can be obtained by averaging the usual cartesian coordinates of the samples informs about the trajectory of the center of mass of the replications. In contrast to such a mean cartesian trajectory, the mean polar trajectory can be used to compute the average circular motion of those replications, and therefore, can yield evidence about sustained steady state oscillations. Both, the coordinate transformation and the computation of confidence intervals, can be carried out efficiently. This results in an efficient method to evaluate stochastic oscillations.

  13. Peak Running Intensity of International Rugby: Implications for Training Prescription.

    PubMed

    Delaney, Jace A; Thornton, Heidi R; Pryor, John F; Stewart, Andrew M; Dascombe, Ben J; Duthie, Grant M

    2017-09-01

    To quantify the duration and position-specific peak running intensities of international rugby union for the prescription and monitoring of specific training methodologies. Global positioning systems (GPS) were used to assess the activity profile of 67 elite-level rugby union players from 2 nations across 33 international matches. A moving-average approach was used to identify the peak relative distance (m/min), average acceleration/deceleration (AveAcc; m/s 2 ), and average metabolic power (P met ) for a range of durations (1-10 min). Differences between positions and durations were described using a magnitude-based network. Peak running intensity increased as the length of the moving average decreased. There were likely small to moderate increases in relative distance and AveAcc for outside backs, halfbacks, and loose forwards compared with the tight 5 group across all moving-average durations (effect size [ES] = 0.27-1.00). P met demands were at least likely greater for outside backs and halfbacks than for the tight 5 (ES = 0.86-0.99). Halfbacks demonstrated the greatest relative distance and P met outputs but were similar to outside backs and loose forwards in AveAcc demands. The current study has presented a framework to describe the peak running intensities achieved during international rugby competition by position, which are considerably higher than previously reported whole-period averages. These data provide further knowledge of the peak activity profiles of international rugby competition, and this information can be used to assist coaches and practitioners in adequately preparing athletes for the most demanding periods of play.

  14. [Importance of occlusion therapy for amblyopia in partial unilateral congenital cataracts that are discovered late].

    PubMed

    Denion, E; Dedes, V; Bonne, M; Labalette, P; Berger, C; Guilbert, F; Bouckehove, S; Rouland, J-F

    2004-11-01

    The aim of this study is to investigate the importance of occlusion therapy for amblyopia in patients with partial unilateral congenital cataracts that were discovered after 24 months of age. A retrospective study was conducted on 11 patients, each of whom underwent a clinical examination including a cycloplegic refraction with atropine. The average age when the cataract was diagnosed was 35 months. The average distance visual acuity was 6/78 and the average near visual acuity was 35/175. Occlusion therapy using adhesive patches was started after refractive error correction. In two cases, observance was mediocre. Ametropia was found in every patient, with anisometropia in nine patients (alpha < 0.02). This anisometropia included an astigmatism that was always greater on the side with the cataract (alpha < 0.001), averaging 2.7 diopters. After occlusion therapy for amblyopia, the average visual acuity significantly improved to 6/22 in distance vision (alpha < 0.02) and 35/45 in near vision (alpha < 0.01). The average follow-up period was 28 months (5-60 months). Amblyopia is related to lens opacities as well as frequently associated anisometropia. Functional improvement is greater in near vision than in distance vision. With occlusion therapy for amblyopia, accommodation is preserved. This factor is of utmost importance as near vision is preferential in young children. This study provides an opportunity to recall the importance of refraction and occlusion therapy for amblyopia, which must be systematically attempted in cases of partial unilateral congenital cataracts before considering a surgical procedure.

  15. A New Paradigm for Supergranulation Derived from Large-Distance Time-Distance Helioseismology: Pancakes

    NASA Technical Reports Server (NTRS)

    Duvall, Thomas L.; Hanasoge, Shravan M.

    2012-01-01

    With large separations (10-24 deg heliocentric), it has proven possible to cleanly separate the horizontal and vertical components of supergranular flow with time-distance helioseismology. These measurements require very broad filters in the k-$\\omega$ power spectrum as apparently supergranulation scatters waves over a large area of the power spectrum. By picking locations of supergranulation as peaks in the horizontal divergence signal derived from f-mode waves, it is possible to simultaneously obtain average properties of supergranules and a high signal/noise ratio by averaging over many cells. By comparing ray-theory forward modeling with HMI measurements, an average supergranule model with a peak upflow of 240 m/s at cell center at a depth of 2.3 Mm and a peak horizontal outflow of 700 m/s at a depth of 1.6 Mm. This upflow is a factor of 20 larger than the measured photospheric upflow. These results may not be consistent with earlier measurements using much shorter separations (<5 deg heliocentric). With a 30 Mm horizontal extent and a few Mm in depth, the cells might be characterized as thick pancakes.

  16. Classification of Pelteobagrus fish in Poyang Lake based on mitochondrial COI gene sequence.

    PubMed

    Zhong, Bin; Chen, Ting-Ting; Gong, Rui-Yue; Zhao, Zhe-Xia; Wang, Binhua; Fang, Chunlin; Mao, Hui-Ling

    2016-11-01

    We use DNA molecular marker technology to correct the deficiency of traditional morphological taxonomy. Totality 770 Pelteobagrus fish from Poyang Lake were collected. After preliminary morphological classification, random selected eight samples in each species for DNA extraction. Mitochondrial COI gene sequence was cloned with universal primers and sequenced. The results showed that there are four species of Pelteobagrus living in Poyang Lake. The average of intraspecific genetic distance value was 0.003, while the average interspecific genetic distance was 0.128. The interspecific genetic distance is far more than intraspecific genetic distance. Besides, phylogenetic tree analysis revealed that molecular systematics was in accord with morphological classification. It indicated that COI gene is an effective DNA molecular marker in Pelteobagrus classification. Surprisingly, the intraspecific difference of some individuals (P. e6, P. n6, P. e5, and P. v4) from their original named exceeded species threshold (2%), which should be renewedly classified into Pelteobagrus fulvidraco. However, another individual P. v3 was very different, because its genetic distance was over 8.4% difference from original named Pelteobagrus vachelli. Its taxonomic status remained to be further studied.

  17. Absolute Ages and Distances of 22 GCs Using Monte Carlo Main-sequence Fitting

    NASA Astrophysics Data System (ADS)

    O'Malley, Erin M.; Gilligan, Christina; Chaboyer, Brian

    2017-04-01

    The recent Gaia Data Release 1 of stellar parallaxes provides ample opportunity to find metal-poor main-sequence stars with precise parallaxes. We select 21 such stars with parallax uncertainties better than σ π /π ≤ 0.10 and accurate abundance determinations suitable for testing metal-poor stellar evolution models and determining the distance to Galactic globular clusters (GCs). A Monte Carlo analysis was used, taking into account uncertainties in the model construction parameters, to generate stellar models and isochrones to fit to the calibration stars. The isochrones that fit the calibration stars best were then used to determine the distances and ages of 22 GCs with metallicities ranging from -2.4 dex to -0.7 dex. We find distances with an average uncertainty of 0.15 mag and absolute ages ranging from 10.8 to 13.6 Gyr with an average uncertainty of 1.6 Gyr. Using literature proper motion data, we calculate orbits for the clusters, finding six that reside within the Galactic disk/bulge, while the rest are considered halo clusters. We find no strong evidence for a relationship between age and Galactocentric distance, but we do find a decreasing age-[Fe/H] relation.

  18. Tracking the dynamics of divergent thinking via semantic distance: Analytic methods and theoretical implications.

    PubMed

    Hass, Richard W

    2017-02-01

    Divergent thinking has often been used as a proxy measure of creative thinking, but this practice lacks a foundation in modern cognitive psychological theory. This article addresses several issues with the classic divergent-thinking methodology and presents a new theoretical and methodological framework for cognitive divergent-thinking studies. A secondary analysis of a large dataset of divergent-thinking responses is presented. Latent semantic analysis was used to examine the potential changes in semantic distance between responses and the concept represented by the divergent-thinking prompt across successive response iterations. The results of linear growth modeling showed that although there is some linear increase in semantic distance across response iterations, participants high in fluid intelligence tended to give more distant initial responses than those with lower fluid intelligence. Additional analyses showed that the semantic distance of responses significantly predicted the average creativity rating given to the response, with significant variation in average levels of creativity across participants. Finally, semantic distance does not seem to be related to participants' choices of their own most creative responses. Implications for cognitive theories of creativity are discussed, along with the limitations of the methodology and directions for future research.

  19. DNA barcoding for species identification in deep-sea clams (Mollusca: Bivalvia: Vesicomyidae).

    PubMed

    Liu, Jun; Zhang, Haibin

    2018-01-15

    Deep-sea clams (Bivalvia: Vesicomyidae) have been found in reduced environments over the world oceans, but taxonomy of this group remains confusing at species and supraspecific levels due to their high-morphological similarity and plasticity. In the present study, we collected mitochondrial COI sequences to evaluate the utility of DNA barcoding on identifying vesicomyid species. COI dataset identified 56 well-supported putative species/operational taxonomic units (OTUs), approximately covering half of the extant vesicomyid species. One species (OTU2) was first detected, and may represent a new species. Average distances between species ranged from 1.65 to 29.64%, generally higher than average intraspecific distances (0-1.41%) when excluding Pliocardia sp.10 cf. venusta (average intraspecific distance 1.91%). Local barcoding gap existed in 33 of the 35 species when comparing distances of maximum interspecific and minimum interspecific distances with two exceptions (Abyssogena southwardae and Calyptogena rectimargo-starobogatovi). The barcode index number (BIN) system determined 41 of the 56 species/OTUs, each with a unique BIN, indicating their validity. Three species were found to have two BINs, together with their high level of intraspecific variation, implying cryptic diversity within them. Although fewer 16 S sequences were collected, similar results were obtained. Nineteen putative species were determined and no overlap observed between intra- and inter-specific variation. Implications of DNA barcoding for the Vesicomyidae taxonomy were then discussed. Findings of this study will provide important evidence for taxonomic revision in this problematic clam group, and accelerate the discovery of new vesicomyid species in the future.

  20. Describing Trails: Distance or Time?

    ERIC Educational Resources Information Center

    Morris, Beverly R.; Bixler, Robert D.

    1998-01-01

    To determine whether trails on visitor maps should indicate distance only or include "time to complete," Cleveland Metroparks interviewed 287 adult visitors to a large regional zoo. The mean perceived "average time to walk a mile" was 17 minutes, but responses ranged from 1.5 to 60 minutes. Half of respondents underestimated…

  1. 20 CFR 655.103 - Overview of this subpart and definition of terms.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...

  2. 20 CFR 655.103 - Overview of this subpart and definition of terms.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...

  3. 20 CFR 655.103 - Overview of this subpart and definition of terms.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...

  4. 29 CFR 501.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...

  5. 29 CFR 501.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...

  6. 29 CFR 501.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...

  7. 29 CFR 501.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...

  8. Improved performance of semiconductor laser tracking frequency gauge

    NASA Astrophysics Data System (ADS)

    Kaplan, D. M.; Roberts, T. J.; Phillips, J. D.; Reasenberg, R. D.

    2018-03-01

    We describe new results from the semiconductor-laser tracking frequency gauge, an instrument that can perform sub-picometer distance measurements and has applications in gravity research and in space-based astronomical instruments proposed for the study of light from extrasolar planets. Compared with previous results, we have improved incremental distance accuracy by a factor of two, to 0.9 pm in 80 s averaging time, and absolute distance accuracy by a factor of 20, to 0.17 μm in 1000 s. After an interruption of operation of a tracking frequency gauge used to control a distance, it is now possible, using a nonresonant measurement interferometer, to restore the distance to picometer accuracy by combining absolute and incremental distance measurements.

  9. Virtual Averaging Making Nonframe-Averaged Optical Coherence Tomography Images Comparable to Frame-Averaged Images.

    PubMed

    Chen, Chieh-Li; Ishikawa, Hiroshi; Wollstein, Gadi; Bilonick, Richard A; Kagemann, Larry; Schuman, Joel S

    2016-01-01

    Developing a novel image enhancement method so that nonframe-averaged optical coherence tomography (OCT) images become comparable to active eye-tracking frame-averaged OCT images. Twenty-one eyes of 21 healthy volunteers were scanned with noneye-tracking nonframe-averaged OCT device and active eye-tracking frame-averaged OCT device. Virtual averaging was applied to nonframe-averaged images with voxel resampling and adding amplitude deviation with 15-time repetitions. Signal-to-noise (SNR), contrast-to-noise ratios (CNR), and the distance between the end of visible nasal retinal nerve fiber layer (RNFL) and the foveola were assessed to evaluate the image enhancement effect and retinal layer visibility. Retinal thicknesses before and after processing were also measured. All virtual-averaged nonframe-averaged images showed notable improvement and clear resemblance to active eye-tracking frame-averaged images. Signal-to-noise and CNR were significantly improved (SNR: 30.5 vs. 47.6 dB, CNR: 4.4 vs. 6.4 dB, original versus processed, P < 0.0001, paired t -test). The distance between the end of visible nasal RNFL and the foveola was significantly different before (681.4 vs. 446.5 μm, Cirrus versus Spectralis, P < 0.0001) but not after processing (442.9 vs. 446.5 μm, P = 0.76). Sectoral macular total retinal and circumpapillary RNFL thicknesses showed systematic differences between Cirrus and Spectralis that became not significant after processing. The virtual averaging method successfully improved nontracking nonframe-averaged OCT image quality and made the images comparable to active eye-tracking frame-averaged OCT images. Virtual averaging may enable detailed retinal structure studies on images acquired using a mixture of nonframe-averaged and frame-averaged OCT devices without concerning about systematic differences in both qualitative and quantitative aspects.

  10. Virtual Averaging Making Nonframe-Averaged Optical Coherence Tomography Images Comparable to Frame-Averaged Images

    PubMed Central

    Chen, Chieh-Li; Ishikawa, Hiroshi; Wollstein, Gadi; Bilonick, Richard A.; Kagemann, Larry; Schuman, Joel S.

    2016-01-01

    Purpose Developing a novel image enhancement method so that nonframe-averaged optical coherence tomography (OCT) images become comparable to active eye-tracking frame-averaged OCT images. Methods Twenty-one eyes of 21 healthy volunteers were scanned with noneye-tracking nonframe-averaged OCT device and active eye-tracking frame-averaged OCT device. Virtual averaging was applied to nonframe-averaged images with voxel resampling and adding amplitude deviation with 15-time repetitions. Signal-to-noise (SNR), contrast-to-noise ratios (CNR), and the distance between the end of visible nasal retinal nerve fiber layer (RNFL) and the foveola were assessed to evaluate the image enhancement effect and retinal layer visibility. Retinal thicknesses before and after processing were also measured. Results All virtual-averaged nonframe-averaged images showed notable improvement and clear resemblance to active eye-tracking frame-averaged images. Signal-to-noise and CNR were significantly improved (SNR: 30.5 vs. 47.6 dB, CNR: 4.4 vs. 6.4 dB, original versus processed, P < 0.0001, paired t-test). The distance between the end of visible nasal RNFL and the foveola was significantly different before (681.4 vs. 446.5 μm, Cirrus versus Spectralis, P < 0.0001) but not after processing (442.9 vs. 446.5 μm, P = 0.76). Sectoral macular total retinal and circumpapillary RNFL thicknesses showed systematic differences between Cirrus and Spectralis that became not significant after processing. Conclusion The virtual averaging method successfully improved nontracking nonframe-averaged OCT image quality and made the images comparable to active eye-tracking frame-averaged OCT images. Translational Relevance Virtual averaging may enable detailed retinal structure studies on images acquired using a mixture of nonframe-averaged and frame-averaged OCT devices without concerning about systematic differences in both qualitative and quantitative aspects. PMID:26835180

  11. Antigenic Distance Measurements for Seasonal Influenza Vaccine Selection

    PubMed Central

    Cai, Zhipeng; Zhang, Tong; Wan, Xiu-Feng

    2011-01-01

    Influenza vaccination is one of the major options to counteract the effects of influenza diseases. Selection of an effective vaccine strain is the key to the success of an effective vaccination program since vaccine protection can only be achieved when the selected influenza vaccine strain matches the antigenic variants causing future outbreaks. Identification of an antigenic variant is the first step to determine whether vaccine strain needs to be updated. Antigenic distance derived from immunological assays, such as hemagglutination inhibition, is commonly used to measure the antigenic closeness between circulating strains and the current influenza vaccine strain. Thus, consensus on an explicit and robust antigenic distance measurement is critical in influenza surveillance. Based on the current seasonal influenza surveillance procedure, we propose and compare three antigenic distance measurements, including Average antigenic distance (A-distance), Mutual antigenic distance (M-distance), and Largest antigenic distance (L-distance). With the assistance of influenza antigenic cartography, our simulation results demonstrated that M-distance is a robust influenza antigenic distance measurement. Experimental results on both simulation and seasonal influenza surveillance data demonstrate that M-distance can be effectively utilized in influenza vaccine strain selection. PMID:22063385

  12. Geographic disparities in patient travel for dialysis in the United States.

    PubMed

    Stephens, J Mark; Brotherton, Samuel; Dunning, Stephan C; Emerson, Larry C; Gilbertson, David T; Harrison, David J; Kochevar, John J; McClellan, Ann C; McClellan, William M; Wan, Shaowei; Gitlin, Matthew

    2013-01-01

    To estimate travel distance and time for US hemodialysis patients and to compare travel of rural versus urban patients. Dialysis patient residences were estimated from ZIP code-level patient counts as of February 2011 allocated within the ZIP code proportional to census tract-level population, obtained from the 2010 U.S. Census. Dialysis facility addresses were obtained from Medicare public-use files. Patients were assigned to an "original" and "replacement" facility, assuming patients used the facility closest to home and would select the next closest facility as a replacement, if a replacement facility was required. Driving distances and times were calculated between patient residences and facility locations using GIS software. The mean one-way driving distance to the original facility was 7.9 miles; for rural patients average distances were 2.5 times farther than for urban patients (15.9 vs. 6.2 miles). Mean driving distance to a replacement facility was 10.6 miles, with rural patients traveling on average 4 times farther than urban patients to a replacement facility (28.8 vs. 6.8 miles). Rural patients travel much longer distances for dialysis than urban patients. Accessing alternative facilities, if required, would greatly increase rural patient travel, while having little impact on urban patients. Increased travel could have clinical implications as longer travel is associated with increased mortality and decreased quality of life. © 2013 National Rural Health Association.

  13. Does running with or without diet changes reduce fat mass in novice runners? A 1-year prospective study.

    PubMed

    Nielsen, Rasmus O; Videbaek, Solvej; Hansen, Mette; Parner, Erik T; Rasmussen, Sten; Langberg, Henning

    2016-01-01

    The aim of this study was to explore how average weekly running distance, combined with changes in diet habits and reasons to take up running, influence fat mass. Fat mass was assessed by bioelectrical impedance at baseline and after 12 months in 538 novice runners included in a 1-year observational prospective follow-up study. During follow-up, running distance for each participant was continuously measured by GPS while reasons to take up running and diet changes were assessed trough web-based questionnaires. Loss of fat mass was compared between runners covering an average of 5 km or more per week and those running shorter distances. Runners who took up running to lose weight and ran over 5 km per week in average over a one-year period combined with a diet change reduced fat mass by -5.58 kg (95% CI: -8.69; -2.46; P<0.001). Compared with subjects also running over 5 km per week but without diet changes, the mean difference in fat mass between groups was 3.81 kg (95% CI: -5.96; -1.66; P<0.001). A difference of -3.55 kg (95% CI: -5.69; -1.41; P<0.001) was found when comparing with those running less than 5 km per week and making changes to their own diet. An average running distance of more than 5 km per week in runners who took up running to lose weight combined with a targeted diet change seems effective in reducing fat mass over a one-year period among novice runners. Still, randomized controlled trials are needed to better document the effects of self-selected diet changes.

  14. A NEW METHOD TO QUANTIFY AND REDUCE THE NET PROJECTION ERROR IN WHOLE-SOLAR-ACTIVE-REGION PARAMETERS MEASURED FROM VECTOR MAGNETOGRAMS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Falconer, David A.; Tiwari, Sanjiv K.; Moore, Ronald L.

    Projection errors limit the use of vector magnetograms of active regions (ARs) far from the disk center. In this Letter, for ARs observed up to 60° from the disk center, we demonstrate a method for measuring and reducing the projection error in the magnitude of any whole-AR parameter that is derived from a vector magnetogram that has been deprojected to the disk center. The method assumes that the center-to-limb curve of the average of the parameter’s absolute values, measured from the disk passage of a large number of ARs and normalized to each AR’s absolute value of the parameter atmore » central meridian, gives the average fractional projection error at each radial distance from the disk center. To demonstrate the method, we use a large set of large-flux ARs and apply the method to a whole-AR parameter that is among the simplest to measure: whole-AR magnetic flux. We measure 30,845 SDO /Helioseismic and Magnetic Imager vector magnetograms covering the disk passage of 272 large-flux ARs, each having whole-AR flux >10{sup 22} Mx. We obtain the center-to-limb radial-distance run of the average projection error in measured whole-AR flux from a Chebyshev fit to the radial-distance plot of the 30,845 normalized measured values. The average projection error in the measured whole-AR flux of an AR at a given radial distance is removed by multiplying the measured flux by the correction factor given by the fit. The correction is important for both the study of the evolution of ARs and for improving the accuracy of forecasts of an AR’s major flare/coronal mass ejection productivity.« less

  15. The precision of locomotor odometry in humans.

    PubMed

    Durgin, Frank H; Akagi, Mikio; Gallistel, Charles R; Haiken, Woody

    2009-03-01

    Two experiments measured the human ability to reproduce locomotor distances of 4.6-100 m without visual feedback and compared distance production with time production. Subjects were not permitted to count steps. It was found that the precision of human odometry follows Weber's law that variability is proportional to distance. The coefficients of variation for distance production were much lower than those measured for time production for similar durations. Gait parameters recorded during the task (average step length and step frequency) were found to be even less variable suggesting that step integration could be the basis for non-visual human odometry.

  16. Evaluation of Observation-Fused Regional Air Quality Model Results for Population Air Pollution Exposure Estimation

    PubMed Central

    Chen, Gang; Li, Jingyi; Ying, Qi; Sherman, Seth; Perkins, Neil; Rajeshwari, Sundaram; Mendola, Pauline

    2014-01-01

    In this study, Community Multiscale Air Quality (CMAQ) model was applied to predict ambient gaseous and particulate concentrations during 2001 to 2010 in 15 hospital referral regions (HRRs) using a 36-km horizontal resolution domain. An inverse distance weighting based method was applied to produce exposure estimates based on observation-fused regional pollutant concentration fields using the differences between observations and predictions at grid cells where air quality monitors were located. Although the raw CMAQ model is capable of producing satisfying results for O3 and PM2.5 based on EPA guidelines, using the observation data fusing technique to correct CMAQ predictions leads to significant improvement of model performance for all gaseous and particulate pollutants. Regional average concentrations were calculated using five different methods: 1) inverse distance weighting of observation data alone, 2) raw CMAQ results, 3) observation-fused CMAQ results, 4) population-averaged raw CMAQ results and 5) population-averaged fused CMAQ results. It shows that while O3 (as well as NOx) monitoring networks in the HRR regions are dense enough to provide consistent regional average exposure estimation based on monitoring data alone, PM2.5 observation sites (as well as monitors for CO, SO2, PM10 and PM2.5 components) are usually sparse and the difference between the average concentrations estimated by the inverse distance interpolated observations, raw CMAQ and fused CMAQ results can be significantly different. Population-weighted average should be used to account spatial variation in pollutant concentration and population density. Using raw CMAQ results or observations alone might lead to significant biases in health outcome analyses. PMID:24747248

  17. A survey of U.S. Fish and Wildlife Service employees regarding topics for distance education-Summary report to respondents

    USGS Publications Warehouse

    Ratz, Joan M.; Shuster, Rudy M.; Marcy, Ann M.

    2011-01-01

    Our preliminary conclusion, based only on frequencies of responses and averages, is that our survey respondents appear to prefer traditional instructor-led training. However, they would still enroll in distance education courses. The distance education technologies of audio conferencing, computer-mediated training, and written resource provision are the technologies respondents reported being most familiar and accessible to them. For four of the five topic areas-creating and maintaining partnerships, technology, program planning and development, and outreach methods-the response frequencies and averages indicate that the topics were viewed as both relevant and important. Respondents were more neutral regarding the relevance and importance of the topic of evaluation methods. Respondents reported preferences for different types of information on different topics and also reported preferences in delivery mode of training for each topic area. Detailed results and conclusions will be included in the completion reports for the two studies.

  18. Solution for a bipartite Euclidean traveling-salesman problem in one dimension

    NASA Astrophysics Data System (ADS)

    Caracciolo, Sergio; Di Gioacchino, Andrea; Gherardi, Marco; Malatesta, Enrico M.

    2018-05-01

    The traveling-salesman problem is one of the most studied combinatorial optimization problems, because of the simplicity in its statement and the difficulty in its solution. We characterize the optimal cycle for every convex and increasing cost function when the points are thrown independently and with an identical probability distribution in a compact interval. We compute the average optimal cost for every number of points when the distance function is the square of the Euclidean distance. We also show that the average optimal cost is not a self-averaging quantity by explicitly computing the variance of its distribution in the thermodynamic limit. Moreover, we prove that the cost of the optimal cycle is not smaller than twice the cost of the optimal assignment of the same set of points. Interestingly, this bound is saturated in the thermodynamic limit.

  19. Solution for a bipartite Euclidean traveling-salesman problem in one dimension.

    PubMed

    Caracciolo, Sergio; Di Gioacchino, Andrea; Gherardi, Marco; Malatesta, Enrico M

    2018-05-01

    The traveling-salesman problem is one of the most studied combinatorial optimization problems, because of the simplicity in its statement and the difficulty in its solution. We characterize the optimal cycle for every convex and increasing cost function when the points are thrown independently and with an identical probability distribution in a compact interval. We compute the average optimal cost for every number of points when the distance function is the square of the Euclidean distance. We also show that the average optimal cost is not a self-averaging quantity by explicitly computing the variance of its distribution in the thermodynamic limit. Moreover, we prove that the cost of the optimal cycle is not smaller than twice the cost of the optimal assignment of the same set of points. Interestingly, this bound is saturated in the thermodynamic limit.

  20. Evaluation of gas well setback policy in the Marcellus Shale region of Pennsylvania in relation to emissions of fine particulate matter.

    PubMed

    Banan, Zoya; Gernand, Jeremy M

    2018-04-18

    Shale gas has become an important strategic energy source with considerable potential economic benefits and the potential to reduce greenhouse gas emissions in so far as it displaces coal use. However, there still exist environmental health risks caused by emissions from exploration and production activities. In the United States, states and localities have set different minimum setback policies to reduce the health risks corresponding to the emissions from these locations, but it is unclear whether these policies are sufficient. This study uses a Gaussian plume model to evaluate the probability of exposure exceedance from EPA concentration limits for PM2.5 at various locations around a generic wellsite in the Marcellus shale region. A set of meteorological data monitored at ten different stations across Marcellus shale gas region in Pennsylvania during 2015 serves as an input to this model. Results indicate that even though the current setback distance policy in Pennsylvania (500 ft. or 152.4 m) might be effective in some cases, exposure limit exceedance occurs frequently at this distance with higher than average emission rates and/or greater number of wells per wellpad. Setback distances should be 736 m to ensure compliance with the daily average concentration of PM2.5, and a function of the number of wells to comply with the annual average PM2.5 exposure standard. The Marcellus Shale gas is known as a significant source of criteria pollutants and studies show that the current setback distance in Pennsylvania is not adequate to protect the residents from exceeding the established limits. Even an effective setback distance to meet the annual exposure limit may not be adequate to meet the daily limit. The probability of exceeding the annual limit increases with number of wells per site. We use a probabilistic dispersion model to introduce a technical basis to select appropriate setback distances.

  1. Radio frequency electromagnetic field compliance assessment of multi-band and MIMO equipped radio base stations.

    PubMed

    Thors, Björn; Thielens, Arno; Fridén, Jonas; Colombi, Davide; Törnevik, Christer; Vermeeren, Günter; Martens, Luc; Joseph, Wout

    2014-05-01

    In this paper, different methods for practical numerical radio frequency exposure compliance assessments of radio base station products were investigated. Both multi-band base station antennas and antennas designed for multiple input multiple output (MIMO) transmission schemes were considered. For the multi-band case, various standardized assessment methods were evaluated in terms of resulting compliance distance with respect to the reference levels and basic restrictions of the International Commission on Non-Ionizing Radiation Protection. Both single frequency and multiple frequency (cumulative) compliance distances were determined using numerical simulations for a mobile communication base station antenna transmitting in four frequency bands between 800 and 2600 MHz. The assessments were conducted in terms of root-mean-squared electromagnetic fields, whole-body averaged specific absorption rate (SAR) and peak 10 g averaged SAR. In general, assessments based on peak field strengths were found to be less computationally intensive, but lead to larger compliance distances than spatial averaging of electromagnetic fields used in combination with localized SAR assessments. For adult exposure, the results indicated that even shorter compliance distances were obtained by using assessments based on localized and whole-body SAR. Numerical simulations, using base station products employing MIMO transmission schemes, were performed as well and were in agreement with reference measurements. The applicability of various field combination methods for correlated exposure was investigated, and best estimate methods were proposed. Our results showed that field combining methods generally considered as conservative could be used to efficiently assess compliance boundary dimensions of single- and dual-polarized multicolumn base station antennas with only minor increases in compliance distances. © 2014 Wiley Periodicals, Inc.

  2. Walking, cycling and transport safety: an analysis of child road deaths.

    PubMed

    Sonkin, Beth; Edwards, Phil; Roberts, Ian; Green, Judith

    2006-08-01

    To examine trends in road death rates for child pedestrians, cyclists and car occupants. Analysis of road traffic injury death rates per 100 000 children and death rates per 10 million passenger miles travelled. England and Wales between 1985 and 2003. Children aged 0-14 years. None. Death rates per 100,000 children and per 10 million child passenger miles for pedestrians, cyclists and car occupants. Death rates per head of population have declined for child pedestrians, cyclists and car occupants but pedestrian death rates remain higher (0.55 deaths/100,000 children; 95% confidence interval [CI] 0.42 to 0.72 deaths) than those for car occupants (0.34 deaths; 95% CI 0.23 to 0.48 deaths) and cyclists (0.16 deaths; 95% CI 0.09 to 0.27 deaths). Since 1985, the average distance children travelled as a car occupant has increased by 70%; the average distance walked has declined by 19%; and the average distance cycled has declined by 58%. Taking into account distance travelled, there are about 50 times more child cyclist deaths (0.55 deaths/10 million passenger miles; 0.32 to 0.89) and nearly 30 times more child pedestrian deaths (0.27 deaths; 0.20 to 0.35) than there are deaths to child car occupants (0.01 deaths; 0.007 to 0.014). In 2003, children from families without access to a vehicle walked twice the distance walked by children in families with access to two or more vehicles. More needs to be done to reduce the traffic injury death rates for child pedestrians and cyclists. This might encourage more walking and cycling and also has the potential to reduce social class gradients in injury mortality.

  3. Phenological differences among selected residents and long-distance migrant bird species in central Europe

    NASA Astrophysics Data System (ADS)

    Bartošová, Lenka; Trnka, Miroslav; Bauer, Zdeněk; Možný, Martin; Štěpánek, Petr; Žalud, Zdeněk

    2014-07-01

    The phenological responses to climate of residents and migrants (short- and long-distance) differ. Although few previous studies have focussed on this topic, the agree that changes in phenology are more apparent for residents than for long-distance migrants. We analysed the breeding times of two selected residents ( Sitta europaea, Parus major) and one long-distance migrant ( Ficedula albicollis) from 1961 to 2007 in central Europe. The timing of the phenophases of all three bird species showed a significant advance to earlier times. Nevertheless, the most marked shift was observed for the long-distance migrant (1.9 days per decade on average in mean laying date with linearity at the 99.9 % confidence level). In contrast, the shifts shown by the residents were smaller (1.6 days for S. europaea and 1.5 days for P. major also on average in mean laying date for both, with linearity at the 95 % confidence level). Spearman rank correlation coefficients calculated for pairs of phenophases of given bird species in 20-year subsamples (e.g. 1961-1980, 1962-1981) showed higher phenological separation between the residents and the migrant. This separation is most apparent after the 1980s. Thus, our results indicate that the interconnections between the studied phenological stages of the three bird species are becoming weaker.

  4. Precipitation in a lead calcium tin anode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perez-Gonzalez, Francisco A., E-mail: fco.aurelio@inbox.com; Centro de Innovacion, Investigacion y Desarrollo en Ingenieria y Tecnologia, Universidad Autonoma de Nuevo Leon; Camurri, Carlos G., E-mail: ccamurri@udec.cl

    Samples from a hot rolled sheet of a tin and calcium bearing lead alloy were solution heat treated at 300 Degree-Sign C and cooled down to room temperature at different rates; these samples were left at room temperature to study natural precipitation of CaSn{sub 3} particles. The samples were aged for 45 days before analysing their microstructure, which was carried out in a scanning electron microscope using secondary and backscattered electron detectors. Selected X-ray spectra analyses were conducted to verify the nature of the precipitates. Images were taken at different magnifications in both modes of observation to locate the precipitatesmore » and record their position within the images and calculate the distance between them. Differential scanning calorimeter analyses were conducted on selected samples. It was found that the mechanical properties of the material correlate with the minimum average distance between precipitates, which is related to the average cooling rate from solution heat treatment. - Highlights: Black-Right-Pointing-Pointer The distance between precipitates in a lead alloy is recorded. Black-Right-Pointing-Pointer The relationship between the distance and the cooling rate is established. Black-Right-Pointing-Pointer It is found that the strengthening of the alloy depends on the distance between precipitates.« less

  5. Electric Field Magnitude and Radar Reflectivity as a Function of Distance from Cloud Edge

    NASA Technical Reports Server (NTRS)

    Ward, Jennifer G.; Merceret, Francis J.

    2004-01-01

    The results of analyses of data collected during a field investigation of thunderstorm anvil and debris clouds are reported. Statistics of the magnitude of the electric field are determined as a function of distance from cloud edge. Statistics of radar reflectivity near cloud edge are also determined. Both analyses use in-situ airborne field mill and cloud physics data coupled with ground-based radar measurements obtained in east-central Florida during the summer convective season. Electric fields outside of anvil and debris clouds averaged less than 3 kV/m. The average radar reflectivity at the cloud edge ranged between 0 and 5 dBZ.

  6. Research on Signature Verification Method Based on Discrete Fréchet Distance

    NASA Astrophysics Data System (ADS)

    Fang, J. L.; Wu, W.

    2018-05-01

    This paper proposes a multi-feature signature template based on discrete Fréchet distance, which breaks through the limitation of traditional signature authentication using a single signature feature. It solves the online handwritten signature authentication signature global feature template extraction calculation workload, signature feature selection unreasonable problem. In this experiment, the false recognition rate (FAR) and false rejection rate (FRR) of the statistical signature are calculated and the average equal error rate (AEER) is calculated. The feasibility of the combined template scheme is verified by comparing the average equal error rate of the combination template and the original template.

  7. Head restraint backset during routine automobile driving: drivers usually exceed the recommended guidelines.

    PubMed

    Shugg, Jarrod A J; Vernest, Kyle; Dickey, James P

    2011-04-01

    Although several previous studies have evaluated horizontal head restraint backset distances, few studies have evaluated them during driving. The purpose of this study was to measure this backset during routine automobile driving and to specifically evaluate the backset during individual driving tasks such as turning, stopping, starting, and lane changes. Fourteen subjects drove around a specified route through the city of Guelph, Ontario, Canada, that included residential, thruway, and highway driving; additional minor driving tasks, such as lane changes, were evaluated. The distance of head restraint to posterior aspect of the head was measured continuously throughout the drive using an ultrasonic measurement system. The timing of specific tasks was documented using a video camera. The average head-to-restraint distance throughout the driving route was 78.1 mm (standard deviation [SD] 24.8 mm); this distance did not vary significantly between the global measures during various driving areas (residential, thruway, and highway). We observed that the head restraint backsets during right turns (93.6 mm; SD 34.8 mm) were significantly larger compared to the other driving tasks (p < .001). The 7 males and 7 females showed similar backset distances: 84.52 mm (SD 12.08) and 71.68 mm (SD 5.53), respectively (p = .0785). We observed that most subjects maintain a relatively consistent head-to-restraint distance throughout their driving route; 2 subjects adopted very large head restraint backset distances throughout their drive and 2 others adopted very small head restraint backset distances-this appears to reflect driver posture. Twelve of 14 subjects had average backset distances that exceed the National Highway Traffic Safety Administration and the Federal Motor Vehicle Safety Standard guidelines, indicating that most drivers may be at risk for whiplash-like disorders if exposed to a rear impact while driving. Of the monitored driving tasks, turning, especially right turns, caused drivers to increase their head-to-restraint backset distance.

  8. Initial Observations of Lingual Movement Characteristics of Children With Cerebral Palsy

    PubMed Central

    Arias, Carlos R.; Morita, Kristen; Richardson, Hannah

    2017-01-01

    Purpose This preliminary study compared the speech motor control of the tongue and jaw between children with cerebral palsy (CP) and their typically developing (TD) peers. Method Tongue tip and jaw movements of 4 boys with spastic CP and 4 age- and sex-matched TD peers were recorded using an electromagnetic articulograph during 10 repetitions of “Dad told stories today.” The duration, path distance, average speed, and speech movement stability of the movements were calculated for each repetition. Results The children with CP had longer durations than their TD peers. Children with CP had longer path distances and faster average speed as compared with their TD peers for both articulators. The TD group but not the CP group had longer path distances and faster average speeds for the tongue than the jaw. The CP group had reduced speech movement stability for the tongue as compared with their TD peers, but both groups had similar speech movement stability for the jaw. Conclusions Children with CP had impaired speech motor control of the tongue and jaw as compared with their TD peers, and these speech motor control deficits were more pronounced in the tongue tip than the jaw. PMID:28655047

  9. Light propagation in Swiss-cheese models of random close-packed Szekeres structures: Effects of anisotropy and comparisons with perturbative results

    NASA Astrophysics Data System (ADS)

    Koksbang, S. M.

    2017-03-01

    Light propagation in two Swiss-cheese models based on anisotropic Szekeres structures is studied and compared with light propagation in Swiss-cheese models based on the Szekeres models' underlying Lemaitre-Tolman-Bondi models. The study shows that the anisotropy of the Szekeres models has only a small effect on quantities such as redshift-distance relations, projected shear and expansion rate along individual light rays. The average angular diameter distance to the last scattering surface is computed for each model. Contrary to earlier studies, the results obtained here are (mostly) in agreement with perturbative results. In particular, a small negative shift, δ DA≔D/A-DA ,b g DA ,b g , in the angular diameter distance is obtained upon line-of-sight averaging in three of the four models. The results are, however, not statistically significant. In the fourth model, there is a small positive shift which has an especially small statistical significance. The line-of-sight averaged inverse magnification at z =1100 is consistent with 1 to a high level of confidence for all models, indicating that the area of the surface corresponding to z =1100 is close to that of the background.

  10. Genomic Diversity in Pig (Sus scrofa) and its Comparison with Human and other Livestock

    PubMed Central

    Zhang, Chunyan; Plastow, Graham

    2011-01-01

    We have reviewed the current pig (Sus scrofa) genomic diversity within and between sites and compared them with human and other livestock. The current Porcine 60K single nucleotide polymorphism (SNP) panel has an average SNP distance in a range of 30 - 40 kb. Most of genetic variation was distributed within populations, and only a small proportion of them existed between populations. The average heterozygosity was lower in pig than in human and other livestock. Genetic inbreeding coefficient (FIS), population differentiation (FST), and Nei’s genetic distance between populations were much larger in pig than in human and other livestock. Higher average genetic distance existed between European and Asian populations than between European or between Asian populations. Asian breeds harboured much larger variability and higher average heterozygosity than European breeds. The samples of wild boar that have been analyzed displayed more extensive genetic variation than domestic breeds. The average linkage disequilibrium (LD) in improved pig breeds extended to 1 - 3 cM, much larger than that in human (~ 30 kb) and cattle (~ 100 kb), but smaller than that in sheep (~ 10 cM). European breeds showed greater LD that decayed more slowly than Asian breeds. We briefly discuss some processes for maintaining genomic diversity in pig, including migration, introgression, selection, and drift. We conclude that, due to the long time of domestication, the pig possesses lower heterozygosity, higher FIS, and larger LD compared with human and cattle. This implies that a smaller effective population size and less informative markers are needed in pig for genome wide association studies. PMID:21966252

  11. Performance analysis of deciduous morphology for detecting biological siblings.

    PubMed

    Paul, Kathleen S; Stojanowski, Christopher M

    2015-08-01

    Family-centered burial practices influence cemetery structure and can represent social group composition in both modern and ancient contexts. In ancient sites dental phenotypic data are often used as proxies for underlying genotypes to identify potential biological relatives. Here, we test the performance of deciduous dental morphological traits for differentiating sibling pairs from unrelated individuals from the same population. We collected 46 deciduous morphological traits for 69 sibling pairs from the Burlington Growth Centre's long term Family Study. Deciduous crown features were recorded following published standards. After variable winnowing, inter-individual Euclidean distances were generated using 20 morphological traits. To determine whether sibling pairs are more phenotypically similar than expected by chance we used bootstrap resampling of distances to generate P values. Multidimensional scaling (MDS) plots were used to evaluate the degree of clustering among sibling pairs. Results indicate an average distance between siblings of 0.252, which is significantly less than 9,999 replicated averages of 69 resampled pseudo-distances generated from: 1) a sample of non-relative pairs (P < 0.001), and 2) a sample of relative and non-relative pairs (P < 0.001). MDS plots indicate moderate to strong clustering among siblings; families occupied 3.83% of the multidimensional space on average (versus 63.10% for the total sample). Deciduous crown morphology performed well in identifying related sibling pairs. However, there was considerable variation in the extent to which different families exhibited similarly low levels of phenotypic divergence. © 2015 Wiley Periodicals, Inc.

  12. Attitudes of Turkish Distance Learners toward Internet-Based Learning: An Investigation Depending on Demographical Characteristics

    ERIC Educational Resources Information Center

    Tekinarslan, Erkan

    2008-01-01

    The purpose of this study is to develop an attitude scale toward Internet-based learning (IBL) and to investigate whether attitude levels of Turkish distance learners in an IBL environment differ according to their demographical characteristics (i.e. age, gender, marital status, parental status, employment status, grade point average (GPA).…

  13. A Classroom Note on: The Average Distance in an Ellipse

    ERIC Educational Resources Information Center

    Gordon, Sheldon P.

    2011-01-01

    This article presents an applied calculus exercise that can be easily shared with students. One of Kepler's greatest discoveries was the fact that the planets move in elliptic orbits with the sun at one focus. Astronomers characterize the orbits of particular planets by their minimum and maximum distances to the sun, known respectively as the…

  14. Automated LSA Assessment of Summaries in Distance Education: Some Variables to Be Considered

    ERIC Educational Resources Information Center

    Jorge-Botana, Guillermo; Luzón, José M.; Gómez-Veiga, Isabel; Martín-Cordero, Jesús I.

    2015-01-01

    A latent semantic analysis-based automated summary assessment is described; this automated system is applied to a real learning from text task in a Distance Education context. We comment on the use of automated content, plagiarism, text coherence measures, and word weights average and their impact on predicting human judges summary scoring. A…

  15. Multilevel lumbar fusion and postoperative physiotherapy rehabilitation in a patient with persistent pain.

    PubMed

    Pons, Tracey; Shipton, Edward A

    2011-04-01

    There are no comparative randomised controlled trials of physiotherapy modalities for chronic low back and radicular pain associated with multilevel fusion. Physiotherapy-based rehabilitation to control pain and improve activation levels for persistent pain following multilevel fusion can be challenging. This is a case report of a 68-year-old man who was referred for physiotherapy intervention 10 months after a multilevel spinal fusion for spinal stenosis. He reported high levels of persistent postoperative pain with minimal activity as a consequence of his pain following the surgery. The physiotherapy interventions consisted of three phases of rehabilitation starting with pool exercise that progressed to land-based walking. These were all combined with transcutaneous electrical nerve stimulation (TENS) that was used consistently for up to 8 hours per day. As outcome measures, daily pain levels and walking distances were charted once the pool programme was completed (in the third phase). Phase progression was determined by shuttle test results. The pain level was correlated with the distance walked using linear regression over a 5-day average. Over a 5-day moving average, the pain level reduced and walking distance increased. The chart of recorded pain level and walking distance showed a trend toward decreased pain with the increased distance walked. In a patient undergoing multilevel lumbar fusion, the combined use of TENS and a progressive walking programme (from pool to land) reduced pain and increased walking distance. This improvement was despite poor medication compliance and a reported high level of postsurgical pain.

  16. Euclidean commute time distance embedding and its application to spectral anomaly detection

    NASA Astrophysics Data System (ADS)

    Albano, James A.; Messinger, David W.

    2012-06-01

    Spectral image analysis problems often begin by performing a preprocessing step composed of applying a transformation that generates an alternative representation of the spectral data. In this paper, a transformation based on a Markov-chain model of a random walk on a graph is introduced. More precisely, we quantify the random walk using a quantity known as the average commute time distance and find a nonlinear transformation that embeds the nodes of a graph in a Euclidean space where the separation between them is equal to the square root of this quantity. This has been referred to as the Commute Time Distance (CTD) transformation and it has the important characteristic of increasing when the number of paths between two nodes decreases and/or the lengths of those paths increase. Remarkably, a closed form solution exists for computing the average commute time distance that avoids running an iterative process and is found by simply performing an eigendecomposition on the graph Laplacian matrix. Contained in this paper is a discussion of the particular graph constructed on the spectral data for which the commute time distance is then calculated from, an introduction of some important properties of the graph Laplacian matrix, and a subspace projection that approximately preserves the maximal variance of the square root commute time distance. Finally, RX anomaly detection and Topological Anomaly Detection (TAD) algorithms will be applied to the CTD subspace followed by a discussion of their results.

  17. Experimental Analysis of Heat Transfer Characteristics and Pressure Drop through Screen Regenerative Heat Exchangers

    DTIC Science & Technology

    1993-12-01

    of fluid T1 initial temperature of matrix and fluid Tf1 average inlet temperature after the step change Tii average inlet temperature before the step...respectively, of the regenerator. The horizontal distances shown with Tf1 , Tj, and T,2 illustrate the time interval for which the average values were...temperature was not a true step function, the investigator made an approximation. The approximation was based on an average temperature. Tf1 was the

  18. Estimating rupture distances without a rupture

    USGS Publications Warehouse

    Thompson, Eric M.; Worden, Charles

    2017-01-01

    Most ground motion prediction equations (GMPEs) require distances that are defined relative to a rupture model, such as the distance to the surface projection of the rupture (RJB) or the closest distance to the rupture plane (RRUP). There are a number of situations in which GMPEs are used where it is either necessary or advantageous to derive rupture distances from point-source distance metrics, such as hypocentral (RHYP) or epicentral (REPI) distance. For ShakeMap, it is necessary to provide an estimate of the shaking levels for events without rupture models, and before rupture models are available for events that eventually do have rupture models. In probabilistic seismic hazard analysis, it is often convenient to use point-source distances for gridded seismicity sources, particularly if a preferred orientation is unknown. This avoids the computationally cumbersome task of computing rupture-based distances for virtual rupture planes across all strikes and dips for each source. We derive average rupture distances conditioned on REPI, magnitude, and (optionally) back azimuth, for a variety of assumed seismological constraints. Additionally, we derive adjustment factors for GMPE standard deviations that reflect the added uncertainty in the ground motion estimation when point-source distances are used to estimate rupture distances.

  19. Longitudinal analysis of student performance in a dental hygiene distance education program.

    PubMed

    Olmsted, Jodi L

    2002-09-01

    The purpose of the study was to determine if learners who receive face-to-face instruction in an educational program performed statistically better on established benchmark assessments (GPA, course averages, and NBDHE) than learners at a distance from the didactic course instructor. A comparative, quasi-experimental, ex-post facto study was conducted. The treatment variable was program type: face-to-face vs. distance. The performance of five consecutive classes was analyzed, from 1997 to 2001. These five classes consisted of 221 learners, 105 of them at the host site and 115 using distance learning. The experimental groups were divided based upon location--host or cooperating college (distance) site learners. Study results identified no significant difference between host and distance learner performance for the entire educational program. The use of interactive television (ITV) for delivery of an educational program using distance education technology provided acceptable results in learner didactic performance. Learners at both the host and cooperating college (distance) sites performed equally well. The results were used to document program outcomes.

  20. Preference for facial averageness: Evidence for a common mechanism in human and macaque infants

    PubMed Central

    Damon, Fabrice; Méary, David; Quinn, Paul C.; Lee, Kang; Simpson, Elizabeth A.; Paukner, Annika; Suomi, Stephen J.; Pascalis, Olivier

    2017-01-01

    Human adults and infants show a preference for average faces, which could stem from a general processing mechanism and may be shared among primates. However, little is known about preference for facial averageness in monkeys. We used a comparative developmental approach and eye-tracking methodology to assess visual attention in human and macaque infants to faces naturally varying in their distance from a prototypical face. In Experiment 1, we examined the preference for faces relatively close to or far from the prototype in 12-month-old human infants with human adult female faces. Infants preferred faces closer to the average than faces farther from it. In Experiment 2, we measured the looking time of 3-month-old rhesus macaques (Macaca mulatta) viewing macaque faces varying in their distance from the prototype. Like human infants, macaque infants looked longer to faces closer to the average. In Experiments 3 and 4, both species were presented with unfamiliar categories of faces (i.e., macaque infants tested with adult macaque faces; human infants and adults tested with infant macaque faces) and showed no prototype preferences, suggesting that the prototypicality effect is experience-dependent. Overall, the findings suggest a common processing mechanism across species, leading to averageness preferences in primates. PMID:28406237

  1. Structural Heterogeneity and Quantitative FRET Efficiency Distributions of Polyprolines through a Hybrid Atomistic Simulation and Monte Carlo Approach

    PubMed Central

    Hoefling, Martin; Lima, Nicola; Haenni, Dominik; Seidel, Claus A. M.; Schuler, Benjamin; Grubmüller, Helmut

    2011-01-01

    Förster Resonance Energy Transfer (FRET) experiments probe molecular distances via distance dependent energy transfer from an excited donor dye to an acceptor dye. Single molecule experiments not only probe average distances, but also distance distributions or even fluctuations, and thus provide a powerful tool to study biomolecular structure and dynamics. However, the measured energy transfer efficiency depends not only on the distance between the dyes, but also on their mutual orientation, which is typically inaccessible to experiments. Thus, assumptions on the orientation distributions and averages are usually made, limiting the accuracy of the distance distributions extracted from FRET experiments. Here, we demonstrate that by combining single molecule FRET experiments with the mutual dye orientation statistics obtained from Molecular Dynamics (MD) simulations, improved estimates of distances and distributions are obtained. From the simulated time-dependent mutual orientations, FRET efficiencies are calculated and the full statistics of individual photon absorption, energy transfer, and photon emission events is obtained from subsequent Monte Carlo (MC) simulations of the FRET kinetics. All recorded emission events are collected to bursts from which efficiency distributions are calculated in close resemblance to the actual FRET experiment, taking shot noise fully into account. Using polyproline chains with attached Alexa 488 and Alexa 594 dyes as a test system, we demonstrate the feasibility of this approach by direct comparison to experimental data. We identified cis-isomers and different static local environments as sources of the experimentally observed heterogeneity. Reconstructions of distance distributions from experimental data at different levels of theory demonstrate how the respective underlying assumptions and approximations affect the obtained accuracy. Our results show that dye fluctuations obtained from MD simulations, combined with MC single photon kinetics, provide a versatile tool to improve the accuracy of distance distributions that can be extracted from measured single molecule FRET efficiencies. PMID:21629703

  2. The Oval Female Facial Shape--A Study in Beauty.

    PubMed

    Goodman, Greg J

    2015-12-01

    Our understanding of who is beautiful seems to be innate but has been argued to conform to mathematical principles and proportions. One aspect of beauty is facial shape that is gender specific. In women, an oval facial shape is considered attractive. To study the facial shape of beautiful actors, pageant title winners, and performers across ethnicities and in different time periods and to construct an ideal oval shape based on the average of their facial shape dimensions. Twenty-one full-face photographs of purportedly beautiful female actors, performers, and pageant winners were analyzed and an oval constructed from their facial parameters. Only 3 of the 21 faces were totally symmetrical, with the most larger in the left upper and lower face. The average oval was subsequently constructed from an average bizygomatic distance (horizontal parameter) of 4.3 times their intercanthal distance (ICD) and a vertical dimension that averaged 6.3 times their ICD. This average oval could be fitted to many of the individual subjects showing a smooth flow from the forehead through temples, cheeks, jaw angle, jawline, and chin with all these facial aspects abutting the oval. Where they did not abut, treatment may have improved these subjects.

  3. A genetic linkage map of the long arm of human chromosome 22.

    PubMed

    Rouleau, G A; Haines, J L; Bazanowski, A; Colella-Crowley, A; Trofatter, J A; Wexler, N S; Conneally, P M; Gusella, J F

    1989-01-01

    We have used a recombinant phage library enriched for chromosome 22 sequences to isolate and characterize eight anonymous DNA probes detecting restriction fragment length polymorphisms on this autosome. These were used in conjunction with eight previously reported loci, including the genes BCR, IGLV, and PDGFB, four anonymous DNA markers, and the P1 blood group antigen, to construct a linkage map for chromosome 22. The linkage group is surprisingly large, spanning 97 cM on the long arm of the chromosome. There are no large gaps in the map; the largest intermarker interval is 14 cM. Unlike several other chromosomes, little overall difference was observed for sex-specific recombination rates on chromosome 22. The availability of a genetic map will facilitate investigation of chromosome 22 rearrangements in such disorders as cat eye syndrome and DiGeorge syndrome, deletions in acoustic neuroma and meningioma, and translocations in Ewing sarcoma. This defined set of linked markers will also permit testing chromosome 22 for the presence of particular disease genes by family studies and should immediately support more precise mapping and identification of flanking markers for NF2, the defective gene causing bilateral acoustic neurofibromatosis.

  4. DNA methylation intratumor heterogeneity in localized lung adenocarcinomas.

    PubMed

    Quek, Kelly; Li, Jun; Estecio, Marcos; Zhang, Jiexin; Fujimoto, Junya; Roarty, Emily; Little, Latasha; Chow, Chi-Wan; Song, Xingzhi; Behrens, Carmen; Chen, Taiping; William, William N; Swisher, Stephen; Heymach, John; Wistuba, Ignacio; Zhang, Jianhua; Futreal, Andrew; Zhang, Jianjun

    2017-03-28

    Cancers are composed of cells with distinct molecular and phenotypic features within a given tumor, a phenomenon termed intratumor heterogeneity (ITH). Previously, we have demonstrated genomic ITH in localized lung adenocarcinomas; however, the nature of methylation ITH in lung cancers has not been well investigated. In this study, we generated methylation profiles of 48 spatially separated tumor regions from 11 localized lung adenocarcinomas and their matched normal lung tissues using Illumina Infinium Human Methylation 450K BeadChip array. We observed methylation ITH within the same tumors, but to a much less extent compared to inter-individual heterogeneity. On average, 25% of all differentially methylated probes compared to matched normal lung tissues were shared by all regions from the same tumors. This is in contrast to somatic mutations, of which approximately 77% were shared events amongst all regions of individual tumors, suggesting that while the majority of somatic mutations were early clonal events, the tumor-specific DNA methylation might be associated with later branched evolution of these 11 tumors. Furthermore, our data showed that a higher extent of DNA methylation ITH was associated with larger tumor size (average Euclidean distance of 35.64 (> 3cm, median size) versus 27.24 (<= 3cm), p = 0.014), advanced age (average Euclidean distance of 34.95 (above 65) verse 28.06 (below 65), p = 0.046) and increased risk of postsurgical recurrence (average Euclidean distance of 35.65 (relapsed patients) versus 29.03 (patients without relapsed), p = 0.039).

  5. Numerical analysis of interface debonding detection in bonded repair with Rayleigh waves

    NASA Astrophysics Data System (ADS)

    Xu, Ying; Li, BingCheng; Lu, Miaomiao

    2017-01-01

    This paper studied how to use the variation of the dispersion curves of Rayleigh wave group velocity to detect interfacial debonding damage between FRP plate and steel beam. Since FRP strengthened steel beam is two layers medium, Rayleigh wave velocity dispersion phenomenon will happen. The interface debonding damage of FRP strengthened steel beam have an obvious effect on the Rayleigh wave velocity dispersion curve. The paper first put forward average Euclidean distance and Angle separation degree to describe the relationship between the different dispersion curves. Numerical results indicate that there is a approximate linear mapping relationship between the average Euclidean distance of dispersion curves and the length of interfacial debonding damage.

  6. Per tree estimates with n-tree distance sampling: an application to increment core data

    Treesearch

    Thomas B. Lynch; Robert F. Wittwer

    2002-01-01

    Per tree estimates using the n trees nearest a point can be obtained by using a ratio of per unit area estimates from n-tree distance sampling. This ratio was used to estimate average age by d.b.h. classes for cottonwood trees (Populus deltoides Bartr. ex Marsh.) on the Cimarron National Grassland. Increment...

  7. Defeating Inequalities in School Access: A Case of Children with Disabilities in Pakistan

    ERIC Educational Resources Information Center

    Hameed, Abdul; Manzoor, Afaf

    2016-01-01

    A recent study reveals that average distance from home to special school for children with disabilities in Punjab is about 11 km. A huge and free transport system is established to overcome the distance barrier. Moreover, the incentives such as free uniform, books, assistive devices and hostel facility along with subsistence allowance of Rs.800…

  8. Biochemical Systematics and Population Genetic Structure of Anopheles Pseudopunctipennis, Vector of Malaria in Central and South America

    DTIC Science & Technology

    1995-01-01

    statistics. Nei’s23 unbiased and Rogers’24 genetic distances were clus- tered by the unweighted pair group method using the arith- metic average ( UPGMA ...Franc0 and others’ and were clustered by UPGMA to produce the phen- ograms shown in Figures 3 and 4. Phenograms produced using other distance measures

  9. Scaling Up: Faculty Workload, Class Size, and Student Satisfaction in a Distance Learning Course on Geographic Information Science.

    ERIC Educational Resources Information Center

    Dibiase, David; Rademacher, Henry J.

    2005-01-01

    This article explores issues of scalability and sustainability in distance learning. The authors kept detailed records of time they spent teaching a course in geographic information science via the World Wide Web over a six-month period, during which class sizes averaged 49 students. The authors also surveyed students' satisfaction with the…

  10. Egomotion Estimation with Optic Flow and Air Velocity Sensors

    DTIC Science & Technology

    2012-01-22

    RUMMELT ADAM J. RUTKOWSKI Acting Technical Advisor, RWW Program Manager This report is...method of distance and groundspeed estimation using an omnidirectional camera, but knowledge of the average scene distance is required. Flight height...varying wind and even over sloped terrain. Our method also does not require any prior knowledge of the environment or the flyer motion states. This

  11. Correction of Motion Artifacts From Shuttle Mode Computed Tomography Acquisitions for Body Perfusion Imaging Applications.

    PubMed

    Ghosh, Payel; Chandler, Adam G; Altinmakas, Emre; Rong, John; Ng, Chaan S

    2016-01-01

    The aim of this study was to investigate the feasibility of shuttle-mode computed tomography (CT) technology for body perfusion applications by quantitatively assessing and correcting motion artifacts. Noncontrast shuttle-mode CT scans (10 phases, 2 nonoverlapping bed locations) were acquired from 4 patients on a GE 750HD CT scanner. Shuttling effects were quantified using Euclidean distances (between-phase and between-bed locations) of corresponding fiducial points on the shuttle and reference phase scans (prior to shuttle mode). Motion correction with nonrigid registration was evaluated using sum-of-squares differences and distances between centers of segmented volumes of interest on shuttle and references images. Fiducial point analysis showed an average shuttling motion of 0.85 ± 1.05 mm (between-bed) and 1.18 ± 1.46 mm (between-phase), respectively. The volume-of-interest analysis of the nonrigid registration results showed improved sum-of-squares differences from 2950 to 597, between-bed distance from 1.64 to 1.20 mm, and between-phase distance from 2.64 to 1.33 mm, respectively, averaged over all cases. Shuttling effects introduced during shuttle-mode CT acquisitions can be computationally corrected for body perfusion applications.

  12. Observations of the interplanetary magnetic field between 0.46 and 1 A.U. by the Mariner 10 spacecraft. Ph.D. Thesis - Catholic Univ. of Am.

    NASA Technical Reports Server (NTRS)

    Behannon, K. W.

    1976-01-01

    Almost continuous measurement of the interplanetary magnetic field (IMF) at a sampling rate of 25 vectors/sec was performed by the magnetic field experiment onboard the Mariner 10 spacecraft during the period November 3, 1973 to April 14, 1974, comprising approximately 5-2/3 solar rotations and extending in radial distance from the sun from 1 to 0.46 AU. A clearly discernible two-sector pattern of field polarity was observed during the last 3-1/2 months of the period, with the dominant polarity toward the sun below the solar equatorial plane. Two compound high-speed solar wind streams were also present during this period, one in each magnetic field sector. Relative fluctuations of the field in magnitude and direction were found to have large time variations, but on average the relative magnitude fluctuations were approximately constant over the range of heliocentric distance covered while the relative directional fluctuations showed a slight decrease on average with increasing distance. The occurrence rate of directional discontinuities was also found to decrease with increasing radial distance from the sun.

  13. Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding.

    PubMed

    Wilke, Claus O; Lenski, Richard E; Adami, Christoph

    2003-02-05

    The rate at which fitness declines as an organism's genome accumulates random mutations is an important variable in several evolutionary theories. At an intuitive level, it might seem natural that random mutations should tend to interact synergistically, such that the rate of mean fitness decline accelerates as the number of random mutations is increased. However, in a number of recent studies, a prevalence of antagonistic epistasis (the tendency of multiple mutations to have a mitigating rather than reinforcing effect) has been observed. We studied in silico the net amount and form of epistatic interactions in RNA secondary structure folding by measuring the fraction of neutral mutants as a function of mutational distance d. We found a clear prevalence of antagonistic epistasis in RNA secondary structure folding. By relating the fraction of neutral mutants at distance d to the average neutrality at distance d, we showed that this prevalence derives from the existence of many compensatory mutations at larger mutational distances. Our findings imply that the average direction of epistasis in simple fitness landscapes is directly related to the density with which fitness peaks are distributed in these landscapes.

  14. Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

    PubMed Central

    Wilke, Claus O; Lenski, Richard E; Adami, Christoph

    2003-01-01

    Background The rate at which fitness declines as an organism's genome accumulates random mutations is an important variable in several evolutionary theories. At an intuitive level, it might seem natural that random mutations should tend to interact synergistically, such that the rate of mean fitness decline accelerates as the number of random mutations is increased. However, in a number of recent studies, a prevalence of antagonistic epistasis (the tendency of multiple mutations to have a mitigating rather than reinforcing effect) has been observed. Results We studied in silico the net amount and form of epistatic interactions in RNA secondary structure folding by measuring the fraction of neutral mutants as a function of mutational distance d. We found a clear prevalence of antagonistic epistasis in RNA secondary structure folding. By relating the fraction of neutral mutants at distance d to the average neutrality at distance d, we showed that this prevalence derives from the existence of many compensatory mutations at larger mutational distances. Conclusions Our findings imply that the average direction of epistasis in simple fitness landscapes is directly related to the density with which fitness peaks are distributed in these landscapes. PMID:12590655

  15. Population Structure of the Primary Malaria Vector in South America, Anopheles darlingi, Using Isozyme, Random Amplified Polymorphic DNA, Internal Transcribed Spacer 2, and Morphologic Markers

    DTIC Science & Technology

    1999-01-01

    distances and identities and Roger?’ genetic distances were clustered by the unweighted pair group method using arithmetic average ( UPGMA ) to produce...Seattle, WA) using the NEIGHBOR program with the UPGMA option and a phenogram was produced with DRAWGRAM, also in PHYLIP 3.X RAPDBOOT5’ was used to...generate 100 pseudoreplicate distance matrices, which were collapsed to form 100 trees with UPGMA . The bootstrap consensus tree was derived from the 100

  16. The crystal structure of tin sulphate, SnSO[subscript 4], and comparison with isostructural SrSO[subscript 4], PbSO[subscript 4], and BaSO[subscript 4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antao, Sytle M.

    2012-10-23

    The crystal structure of tin (II) sulphate, SnSO{sub 4}, was obtained by Rietveld refinement using synchrotron high-resolution powder X-ray diffraction (HRPXRD) data. The structure was refined in space group Pbnm. The unit-cell parameters for SnSO{sub 4} are a = 7.12322(1), b = 8.81041(1), c = 5.32809(1) {angstrom}, and V = 334.383(1) {angstrom}{sup 3}. The average [12] distance is 2.9391(4) {angstrom}. However, the Sn{sup 2+} cation has a pyramidal [3]-coordination to O atoms and the average [3] = 2.271(1) {angstrom}. If Sn is considered as [12]-coordinated, SnSO{sub 4} has a structure similar to barite, BaSO{sub 4}, and its structuralmore » parameters are intermediate between those of BaSO{sub 4} and PbSO{sub 4}. The tetrahedral SO{sub 4} group has an average [4] = 1.472(1) {angstrom} in SnSO{sub 4}. Comparing SnSO{sub 4} with the isostructural SrSO{sub 4}, PbSO{sub 4}, and BaSO{sub 4}, several well-defined trends are observed. The radii, rM, of the M{sup 2+}(=Sr, Pb, Sn, and Ba) cations and average distances vary linearly with V because of the effective size of the M{sup 2+} cation. Based on the trend for the isostructural sulphates, the average [12] distance is slightly longer than expected because of the lone pair of electrons on the Sn{sup 2+} cation.« less

  17. Study of the effect of electromagnetic fields on indoor and outdoor radon concentrations

    NASA Astrophysics Data System (ADS)

    Haider, Lina M.; Shareef, N. R.; Darwoysh, H. H.; Mansour, H. L.

    2018-05-01

    In the present work, the effect of electromagnetic fields produced by high voltage power lines(132kV) and indoor equipments on the indoor and outdoor average radon concentrations in Al-Kazaliya and Hay Al-Adil regions in Baghdad city were studied using CR-39 track detectors and a gauss-meter.Results of measurements of the present study, have shown that the highest value for the indoor average radon concentration (76.56± 8.44 Bq / m3) was recorded for sample A1(Hay Al-Adel) at a distance of (20 m) from the high voltage power lines, while the lowest value for the indoor average radon concentration (30.46 ± 8.44 Bq / m3) was recorded for sample A3 (Hay Al-Adil) at a distance of (50 m) from the high voltage power lines. The indoor gaussmeter measurements were found to be ranged from (30.2 mG) to (38.5 mG). The higest value for outdoor average radon concentration and the highest gaussmeter measurements were found for sample (1), with values (92.63 ±11.2 Bq / m3) and (87.24 ± 2.85 mG), directly under the high voltage power lines respectively, while the lowest outdoor average radon concentration and the lowest gaussmeter measurements were found in sample (4),with values (34.19 ± 6.33 Bq / m3) and (1.16 ± 0.14 Bq / m3),), at a distance of (120 m) from the high voltage power lines respectively. The results of the present work have shown that there might be an influence of the electromagnetic field on radon concentrations in areas which were close to high voltage power lines and houses which have used many electric equipment for a long period of time.

  18. [Further study on possibility of diffusion of Oncomelania hupensis with water in river channels of the east route of South-to-North Water Diversion Project].

    PubMed

    Huang, Yi-Xin; Hang, De-Rong; Tang, Hong-Ping; Sun, Dao-Kuan; Zhou, Can-Hua; Gao, Jin-Bin; Zheng, Bo; Hu, Gui-Quan; Li, Qian; Huang, Yong-Jun; She, Guang-Song; Ren, Zhi-Yuan

    2014-12-01

    To study the drifting law of floats and potential risks of Oncomelania hupensis diffusion in the water diversion rivers of the east route of South-to-North Water Diversion Project. The O. hupensis snails in the river channels were monitored by the salvage method and snail luring method with rice straw curtains, and the diffusion possibility of snails along with water was assessed through the drift test of floats with GPS. In the flood seasons from 2006 to 2013, totally 8 338.0 kg of floats were salvaged, and 2 100 rice straw curtains were put into water in the Li Canal and Jinbao shipping channel, but no Oncomelania snails were found. The drift test of floats with GPS before water diversion showed that the flow velocity on water surface (northbound) was 0.45 m/s, the average drift velocity of the floats was 0.56 - 0.60 m/s, and the average drift distances each time were 999.70 - 1 995.50 m in the Gaoshui River section, while there were no obvious drift in Jinbao shipping channel section. During the water diversion period, the flow velocity on water surface (northbound) was 0.45 m/s, the average drift velocity of the floats was 0.35 - 0.41m/s, and the average drift distances each time were 1 248.06 -1 289.44 m in the Gaoshui River, while in Jinbao shipping channel section, the flow velocity on water surface was 0.28 m/s, the average drift velocity of the floats was 0.25 - 0.27 m/s, and the average drift distances each time were 477.76 - 496.38 m. The drift test showed that the floats gradually closed to the river bank as affected by water flow, wind direction and ship waves, when blocked by the reeds, water plants or other obstacles, and they would stopped and could not continue to drift without outside help. There are no Oncomelania snails found in the river channels of the east route of South-to-North Water Diversion Project. The drifting distance of the floating debris along with the water is restricted by the flow rate and shore environment.

  19. Outdoor air pollution in close proximity to a continuous point source

    NASA Astrophysics Data System (ADS)

    Klepeis, Neil E.; Gabel, Etienne B.; Ott, Wayne R.; Switzer, Paul

    Data are lacking on human exposure to air pollutants occurring in ground-level outdoor environments within a few meters of point sources. To better understand outdoor exposure to tobacco smoke from cigarettes or cigars, and exposure to other types of outdoor point sources, we performed more than 100 controlled outdoor monitoring experiments on a backyard residential patio in which we released pure carbon monoxide (CO) as a tracer gas for continuous time periods lasting 0.5-2 h. The CO was emitted from a single outlet at a fixed per-experiment rate of 120-400 cc min -1 (˜140-450 mg min -1). We measured CO concentrations every 15 s at up to 36 points around the source along orthogonal axes. The CO sensors were positioned at standing or sitting breathing heights of 2-5 ft (up to 1.5 ft above and below the source) and at horizontal distances of 0.25-2 m. We simultaneously measured real-time air speed, wind direction, relative humidity, and temperature at single points on the patio. The ground-level air speeds on the patio were similar to those we measured during a survey of 26 outdoor patio locations in 5 nearby towns. The CO data exhibited a well-defined proximity effect similar to the indoor proximity effect reported in the literature. Average concentrations were approximately inversely proportional to distance. Average CO levels were approximately proportional to source strength, supporting generalization of our results to different source strengths. For example, we predict a cigarette smoker would cause average fine particle levels of approximately 70-110 μg m -3 at horizontal distances of 0.25-0.5 m. We also found that average CO concentrations rose significantly as average air speed decreased. We fit a multiplicative regression model to the empirical data that predicts outdoor concentrations as a function of source emission rate, source-receptor distance, air speed and wind direction. The model described the data reasonably well, accounting for ˜50% of the log-CO variability in 5-min CO concentrations.

  20. A Robust Step Detection Algorithm and Walking Distance Estimation Based on Daily Wrist Activity Recognition Using a Smart Band.

    PubMed

    Trong Bui, Duong; Nguyen, Nhan Duc; Jeong, Gu-Min

    2018-06-25

    Human activity recognition and pedestrian dead reckoning are an interesting field because of their importance utilities in daily life healthcare. Currently, these fields are facing many challenges, one of which is the lack of a robust algorithm with high performance. This paper proposes a new method to implement a robust step detection and adaptive distance estimation algorithm based on the classification of five daily wrist activities during walking at various speeds using a smart band. The key idea is that the non-parametric adaptive distance estimator is performed after two activity classifiers and a robust step detector. In this study, two classifiers perform two phases of recognizing five wrist activities during walking. Then, a robust step detection algorithm, which is integrated with an adaptive threshold, peak and valley correction algorithm, is applied to the classified activities to detect the walking steps. In addition, the misclassification activities are fed back to the previous layer. Finally, three adaptive distance estimators, which are based on a non-parametric model of the average walking speed, calculate the length of each strike. The experimental results show that the average classification accuracy is about 99%, and the accuracy of the step detection is 98.7%. The error of the estimated distance is 2.2⁻4.2% depending on the type of wrist activities.

  1. An improved initialization center k-means clustering algorithm based on distance and density

    NASA Astrophysics Data System (ADS)

    Duan, Yanling; Liu, Qun; Xia, Shuyin

    2018-04-01

    Aiming at the problem of the random initial clustering center of k means algorithm that the clustering results are influenced by outlier data sample and are unstable in multiple clustering, a method of central point initialization method based on larger distance and higher density is proposed. The reciprocal of the weighted average of distance is used to represent the sample density, and the data sample with the larger distance and the higher density are selected as the initial clustering centers to optimize the clustering results. Then, a clustering evaluation method based on distance and density is designed to verify the feasibility of the algorithm and the practicality, the experimental results on UCI data sets show that the algorithm has a certain stability and practicality.

  2. Improved UUV Positioning Using Acoustic Communications and a Potential for Real-Time Networking and Collaboration

    DTIC Science & Technology

    2017-06-01

    12 III. ACOUSTIC WAVE TRAVEL TIME ESTIMATION...Mission ...............................125 Table 8. Average Horizontal Distance from the UUV to the Reference Points when a Travel Time Measurement is...Taken ............................................126 Table 9. Average UUV Depth when a Travel Time Measurement is Taken .........126 Table 10. Ratio

  3. Measuring multiple spike train synchrony.

    PubMed

    Kreuz, Thomas; Chicharro, Daniel; Andrzejak, Ralph G; Haas, Julie S; Abarbanel, Henry D I

    2009-10-15

    Measures of multiple spike train synchrony are essential in order to study issues such as spike timing reliability, network synchronization, and neuronal coding. These measures can broadly be divided in multivariate measures and averages over bivariate measures. One of the most recent bivariate approaches, the ISI-distance, employs the ratio of instantaneous interspike intervals (ISIs). In this study we propose two extensions of the ISI-distance, the straightforward averaged bivariate ISI-distance and the multivariate ISI-diversity based on the coefficient of variation. Like the original measure these extensions combine many properties desirable in applications to real data. In particular, they are parameter-free, time scale independent, and easy to visualize in a time-resolved manner, as we illustrate with in vitro recordings from a cortical neuron. Using a simulated network of Hindemarsh-Rose neurons as a controlled configuration we compare the performance of our methods in distinguishing different levels of multi-neuron spike train synchrony to the performance of six other previously published measures. We show and explain why the averaged bivariate measures perform better than the multivariate ones and why the multivariate ISI-diversity is the best performer among the multivariate methods. Finally, in a comparison against standard methods that rely on moving window estimates, we use single-unit monkey data to demonstrate the advantages of the instantaneous nature of our methods.

  4. Time structure of the EAS electron and muon components measured by the KASCADE Grande experiment

    NASA Astrophysics Data System (ADS)

    Apel, W. D.; Arteaga, J. C.; Badea, A. F.; Bekk, K.; Bertaina, M.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Brüggemann, M.; Buchholz, P.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Engler, J.; Finger, M.; Fuhrmann, D.; Ghia, P. L.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kickelbick, D.; Klages, H. O.; Kolotaev, Y.; Luczak, P.; Mathes, H. J.; Mayer, H. J.; Meurer, C.; Milke, J.; Mitrica, B.; Morello, C.; Navarra, G.; Nehls, S.; Oehlschläger, J.; Ostapchenko, S.; Over, S.; Petcu, M.; Pierog, T.; Plewnia, S.; Rebel, H.; Roth, M.; Schieler, H.; Sima, O.; Stümpert, M.; Toma, G.; Trinchero, G. C.; Ulrich, H.; van Buren, J.; Walkowiak, W.; Weindl, A.; Wochele, J.; Zabierowski, J.

    2008-06-01

    Extensive air showers measured by the KASCADE-Grande experiment at the Forschungszentrum Karlsruhe are studied with respect to the arrival times of electrons and muons at observation level. The mean and the spread of the arrival time distributions have been used to determine the average time profile of the electromagnetic and muonic shower disk. For core distances R>200m particles of the muonic shower component arrive on average earlier at observation level than particles of the electromagnetic shower component. The difference increases with the core distance from Δ=(12.9±0.2)ns at R>200m to Δ=(47±1)ns at R=500m, where the width of the muonic and electromagnetic shower disks are comparable. This difference in arrival time is used to separate the electrons and muons dependent on the distance from the shower center. This is intended to be used by experiments with time resolving detectors.

  5. Control of the positional relationship between a sample collection instrument and a surface to be analyzed during a sampling procedure with image analysis

    DOEpatents

    Van Berkel, Gary J.; Kertesz, Vilmos

    2011-08-09

    A system and method utilizes an image analysis approach for controlling the collection instrument-to-surface distance in a sampling system for use, for example, with mass spectrometric detection. Such an approach involves the capturing of an image of the collection instrument or the shadow thereof cast across the surface and the utilization of line average brightness (LAB) techniques to determine the actual distance between the collection instrument and the surface. The actual distance is subsequently compared to a target distance for re-optimization, as necessary, of the collection instrument-to-surface during an automated surface sampling operation.

  6. Ranking prediction model using the competition record of Ladies Professional Golf Association players.

    PubMed

    Chae, Jin Seok; Park, Jin; So, Wi-Young

    2017-07-28

    The purpose of this study was to suggest a ranking prediction model using the competition record of the Ladies Professional Golf Association (LPGA) players. The top 100 players on the tour money list from the 2013-2016 US Open were analyzed in this model. Stepwise regression analysis was conducted to examine the effect of performance and independent variables (i.e., driving accuracy, green in regulation, putts per round, driving distance, percentage of sand saves, par-3 average, par-4 average, par-5 average, birdies average, and eagle average) on dependent variables (i.e., scoring average, official money, top-10 finishes, winning percentage, and 60-strokes average). The following prediction model was suggested:Y (Scoring average) = 55.871 - 0.947 (Birdies average) + 4.576 (Par-4 average) - 0.028 (Green in regulation) - 0.012 (Percentage of sand saves) + 2.088 (Par-3 average) - 0.026 (Driving accuracy) - 0.017 (Driving distance) + 0.085 (Putts per round)Y (Official money) = 6628736.723 + 528557.907 (Birdies average) - 1831800.821 (Par-4 average) + 11681.739 (Green in regulation) + 6476.344 (Percentage of sand saves) - 688115.074 (Par-3 average) + 7375.971 (Driving accuracy)Y (Top-10 finish%) = 204.462 + 12.562 (Birdies average) - 47.745 (Par-4 average) + 1.633 (Green in regulation) - 5.151 (Putts per round) + 0.132 (Percentage of sand saves)Y (Winning percentage) = 49.949 + 3.191 (Birdies average) - 15.023 (Par-4 average) + 0.043 (Percentage of sand saves)Y (60-strokes average) = 217.649 + 13.978 (Birdies average) - 44.855 (Par-4 average) - 22.433 (Par-3 average) + 0.16 (Green in regulation)Scoring of the above five prediction models and the prediction of golf ranking in the 2016 Women's Golf Olympic competition in Rio revealed a significant correlation between the predicted and real ranking (r = 0.689, p < 0.001) and between the predicted and the real average score (r = 0.653, p < 0.001). Our ranking prediction model using LPGA data may help coaches and players to identify which players are likely to participate in Olympic and World competitions, based on their performance.

  7. Genetic profile based upon 15 microsatellites of four caste groups of the eastern Indian state, Bihar.

    PubMed

    Ashma, R; Kashyap, V K

    2003-01-01

    The formation of caste groups among the Hindu community and the practice of endogamy exert a great impact on the genetic structure and diversity of the Indian population. Allele frequency data of 15 microsatellite loci clearly portray the genetic diversity and relatedness among four socio-culturally advanced caste groups: Brahmin, Bhumihar, Rajput and Kayasth of Caucasoid ethnicity of Bihar. The study seeks to understand the impact of the man-made caste system on the genetic profile of the four major caste groups of Bihar. Computation of average heterozygosity, most frequent allele, allele diversity and coefficient of gene differentiation (Gst), along with genetic distance (DA)and principal coordinate analysis were performed to assess intra-population and inter-population diversity. The average Gst value for all the loci was 0.012 +/- 0.0033, and the level of average heterozygosity was approximately 75.5%, indicating genetic similarity and intra-population diversity. Genetic distance (DA) values and the phylogenetic tree along with other higher caste groups of India indicate the relative distance between them. The present study clearly depicts the genetic profile of these caste groups, their inherent closeness in the past, and the impact of the imposed caste system that later restricted the gene flow. The study highlights the status of Bhumihar and Kayasth in the Hindu caste system. The former was found clustering with the Brahmin group (as expected, since Bhumihar is known to be a subclass of Brahmin), whereas the distance between the Brahmin and Kayasth caste groups was found to be large. North-eastern Indian Mongoloids form a separate cluster.

  8. Evidence that dorsally mounted satellite transmitters affect migration chronology of Northern Pintails

    USGS Publications Warehouse

    Hupp, Jerry W.; Kharitonov, Sergei; Yamaguchi, Noriyuki M.; Ozaki, K.; Flint, Paul L.; Pearce, John M.; Tokita, Ken-ichi; Shimada, Tetsuo; Higuchi, Hiroyoshi

    2015-01-01

    We compared migration movements and chronology between Northern Pintails (Anas acuta) marked with dorsally mounted satellite transmitters and pintails marked only with tarsus rings. During weekly intervals of spring and autumn migration between their wintering area in Japan and nesting areas in Russia, the mean distance that ringed pintails had migrated was up to 1000 km farther than the mean distance radiomarked pintails migrated. Radiomarked pintails were detected at spring migration sites on average 9.9 days (90 % CI 8.0, 11.8) later than ringed pintails that were recovered within 50 km. Although ringed and radiomarked pintails departed from Japan on similar dates, the disparity in detection of radiomarked versus ringed pintails at shared sites increased 7.7 days (90 % CI 5.2, 10.2) for each 1000 km increase in distance from Japan. Thus, pintails marked with satellite transmitters arrived at nesting areas that were 2500 km from Japan on average 19 days later than ringed birds. Radiomarked pintails were detected at autumn migration stopovers on average 13.1 days (90 % CI 9.8, 16.4) later than ringed birds that were recovered within 50 km. We hypothesize that dorsal attachment of 12–20 g satellite transmitters to Northern Pintails increased the energetic cost of flight, which resulted in more rapid depletion of energetic reserves and shortened the distance pintails could fly without refueling. Radiomarked pintails may have used more stopovers or spent longer periods at stopovers. causing their migration schedule to diverge from ringed pintails. We urge further evaluation of the effects of dorsally mounted transmitters on migration chronology of waterfowl.

  9. Derivation of Hamaker Dispersion Energy of Amorphous Carbon Surfaces in Contact with Liquids Using Photoelectron Energy-Loss Spectra

    NASA Astrophysics Data System (ADS)

    Godet, Christian; David, Denis

    2017-12-01

    Hamaker interaction energies and cutoff distances have been calculated for disordered carbon films, in contact with purely dispersive (diiodomethane) or polar (water) liquids, using their experimental dielectric functions ɛ ( q, ω) obtained over a broad energy range. In contrast with previous works, a q-averaged < ɛ ( q, ω) > q is derived from photoelectron energy-loss spectroscopy (XPS-PEELS) where the energy loss function (ELF) < Im[-1/ ɛ ( q, ω)] > q is a weighted average over allowed transferred wave vector values, q, given by the physics of bulk plasmon excitation. For microcrystalline diamond and amorphous carbon films with a wide range of (sp3/sp2 + sp3) hybridization, non-retarded Hamaker energies, A 132 ( L < 1 nm), were calculated in several configurations, and distance and wavenumber cutoff values were then calculated based on A 132 and the dispersive work of adhesion obtained from contact angles. A geometric average approximation, H 0 CVL = ( H 0 CVC H 0 LVL )1/2, holds for the cutoff separation distances obtained for carbon-vacuum-liquid (CVL), carbon-vacuum-carbon (CVC) and liquid-vacuum-liquid (LVL) equilibrium configurations. The linear dependence found for A CVL, A CLC and A CLV values as a function of A CVC, for each liquid, allows predictive relationships for Hamaker energies (in any configuration) using experimental determination of the dispersive component of the surface tension, {γ}_{CV}^d , and a guess value of the cutoff distance H 0 CVC of the solid. [Figure not available: see fulltext.

  10. Feasibility of Using the Marginal Blood Vessels as Reference Landmarks for CT Colonography

    PubMed Central

    Wei, Zhuoshi; Yao, Jianhua; Wang, Shijun; Liu, Jiamin; Dwyer, Andrew J.; Pickhardt, Perry J.; Nowinski, Wieslaw L.; Summers, Ronald M.

    2015-01-01

    OBJECTIVE The purpose of this study was to show the spatial relationship of the colonic marginal blood vessels and the teniae coli on CT colonography (CTC) and the use of the marginal blood vessels for supine-prone registration of polyps and for determination of proper connectivity of collapsed colonic segments. MATERIALS AND METHODS We manually labeled the marginal blood vessels on 15 CTC examinations. Colon segmentation, centerline extraction, teniae detection, and teniae identification were automatically performed. For assessment of their spatial relationships, the distances from the marginal blood vessels to the three teniae coli and to the colon were measured. Student t tests (paired, two-tailed) were performed to evaluate the differences among these distances. To evaluate the reliability of the marginal vessels as reference points for polyp correlation, we analyzed 20 polyps from 20 additional patients who underwent supine and prone CTC. The average difference of the circumferential polyp position on the supine and prone scans was computed. Student t tests (paired, two-tailed) were performed to evaluate the supine-prone differences of the distance. We performed a study on 10 CTC studies from 10 patients with collapsed colonic segments by manually tracing the marginal blood vessels near the collapsed regions to resolve the ambiguity of the colon path. RESULTS The average distances (± SD) from the marginal blood vessels to the tenia mesocolica, tenia omentalis, and tenia libera were 20.1 ± 3.1 mm (95% CI, 18.5–21.6 mm), 39.5 ± 4.8 mm (37.1–42.0 mm), and 36.9 ± 4.2 mm (34.8–39.1 mm), respectively. Pairwise comparison showed that these distances to the tenia libera and tenia omentalis were significantly different from the distance to the tenia mesocolica (p < 0.001). The average distance from the marginal blood vessels to the colon wall was 15.3 ± 2.0 mm (14.2–16.3 mm). For polyp localization, the average difference of the circumferential polyp position on the supine and prone scans was 9.6 ± 9.4 mm (5.5–13.7 mm) (p = 0.15) and expressed as a percentage of the colon circumference was 3.1% ± 2.0% (2.3–4.0%) (p = 0.83). We were able to trace the marginal blood vessels for 10 collapsed colonic segments and determine the paths of the colon in these regions. CONCLUSION The marginal blood vessels run parallel to the colon in proximity to the tenia mesocolica and enable accurate supine-prone registration of polyps and localization of the colon path in areas of collapse. Thus, the marginal blood vessels may be used as reference landmarks complementary to the colon centerline and teniae coli. PMID:24370165

  11. Spread of dwarf mistletoe from discrete seed sources into young stands of ponderosa and Jeffrey pines

    Treesearch

    J. R. Parmeter Jr.

    1972-01-01

    The maximum distance of spread of dwarf mistletoes from isolated overstory pines into surrounding reproduction averages 120 feet. The rate of infection in young trees declined as distance from the seed source increased and was generally greatest in the direction of prevailing winds. This pattern of infection was similar to the previously reported pattern of seed...

  12. Interactive Online Distance Learning at the University of Hawai'i-West O'ahu

    ERIC Educational Resources Information Center

    Lee, Rebecca

    2002-01-01

    From its beginnings 25 years ago, the University of Hawai'i-West O'ahu (UH-West O'ahu) has strived to provide its students, mostly working adults with an average age of 32 years, with easy access to classes and advising by maintaining flexible class schedules and office hours. When UH-West O'ahu initiated a distance education program in 1981, the…

  13. The Statistical Fermi Paradox

    NASA Astrophysics Data System (ADS)

    Maccone, C.

    In this paper is provided the statistical generalization of the Fermi paradox. The statistics of habitable planets may be based on a set of ten (and possibly more) astrobiological requirements first pointed out by Stephen H. Dole in his book Habitable planets for man (1964). The statistical generalization of the original and by now too simplistic Dole equation is provided by replacing a product of ten positive numbers by the product of ten positive random variables. This is denoted the SEH, an acronym standing for “Statistical Equation for Habitables”. The proof in this paper is based on the Central Limit Theorem (CLT) of Statistics, stating that the sum of any number of independent random variables, each of which may be ARBITRARILY distributed, approaches a Gaussian (i.e. normal) random variable (Lyapunov form of the CLT). It is then shown that: 1. The new random variable NHab, yielding the number of habitables (i.e. habitable planets) in the Galaxy, follows the log- normal distribution. By construction, the mean value of this log-normal distribution is the total number of habitable planets as given by the statistical Dole equation. 2. The ten (or more) astrobiological factors are now positive random variables. The probability distribution of each random variable may be arbitrary. The CLT in the so-called Lyapunov or Lindeberg forms (that both do not assume the factors to be identically distributed) allows for that. In other words, the CLT "translates" into the SEH by allowing an arbitrary probability distribution for each factor. This is both astrobiologically realistic and useful for any further investigations. 3. By applying the SEH it is shown that the (average) distance between any two nearby habitable planets in the Galaxy may be shown to be inversely proportional to the cubic root of NHab. This distance is denoted by new random variable D. The relevant probability density function is derived, which was named the "Maccone distribution" by Paul Davies in 2008. 4. A practical example is then given of how the SEH works numerically. Each of the ten random variables is uniformly distributed around its own mean value as given by Dole (1964) and a standard deviation of 10% is assumed. The conclusion is that the average number of habitable planets in the Galaxy should be around 100 million ±200 million, and the average distance in between any two nearby habitable planets should be about 88 light years ±40 light years. 5. The SEH results are matched against the results of the Statistical Drake Equation from reference 4. As expected, the number of currently communicating ET civilizations in the Galaxy turns out to be much smaller than the number of habitable planets (about 10,000 against 100 million, i.e. one ET civilization out of 10,000 habitable planets). The average distance between any two nearby habitable planets is much smaller that the average distance between any two neighbouring ET civilizations: 88 light years vs. 2000 light years, respectively. This means an ET average distance about 20 times higher than the average distance between any pair of adjacent habitable planets. 6. Finally, a statistical model of the Fermi Paradox is derived by applying the above results to the coral expansion model of Galactic colonization. The symbolic manipulator "Macsyma" is used to solve these difficult equations. A new random variable Tcol, representing the time needed to colonize a new planet is introduced, which follows the lognormal distribution, Then the new quotient random variable Tcol/D is studied and its probability density function is derived by Macsyma. Finally a linear transformation of random variables yields the overall time TGalaxy needed to colonize the whole Galaxy. We believe that our mathematical work in deriving this STATISTICAL Fermi Paradox is highly innovative and fruitful for the future.

  14. Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel.

    PubMed

    Khatkar, Mehar S; Nicholas, Frank W; Collins, Andrew R; Zenger, Kyall R; Cavanagh, Julie A L; Barris, Wes; Schnabel, Robert D; Taylor, Jeremy F; Raadsma, Herman W

    2008-04-24

    The extent of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted selection. Most studies on LD in cattle reported to date are based on microsatellite markers or small numbers of single nucleotide polymorphisms (SNPs) covering one or only a few chromosomes. This is the first comprehensive study on the extent of LD in cattle by analyzing data on 1,546 Holstein-Friesian bulls genotyped for 15,036 SNP markers covering all regions of all autosomes. Furthermore, most studies in cattle have used relatively small sample sizes and, consequently, may have had biased estimates of measures commonly used to describe LD. We examine minimum sample sizes required to estimate LD without bias and loss in accuracy. Finally, relatively little information is available on comparative LD structures including other mammalian species such as human and mouse, and we compare LD structure in cattle with public-domain data from both human and mouse. We computed three LD estimates, D', Dvol and r2, for 1,566,890 syntenic SNP pairs and a sample of 365,400 non-syntenic pairs. Mean D' is 0.189 among syntenic SNPs, and 0.105 among non-syntenic SNPs; mean r2 is 0.024 among syntenic SNPs and 0.0032 among non-syntenic SNPs. All three measures of LD for syntenic pairs decline with distance; the decline is much steeper for r2 than for D' and Dvol. The value of D' and Dvol are quite similar. Significant LD in cattle extends to 40 kb (when estimated as r2) and 8.2 Mb (when estimated as D'). The mean values for LD at large physical distances are close to those for non-syntenic SNPs. Minor allelic frequency threshold affects the distribution and extent of LD. For unbiased and accurate estimates of LD across marker intervals spanning < 1 kb to > 50 Mb, minimum sample sizes of 400 (for D') and 75 (for r2) are required. The bias due to small samples sizes increases with inter-marker interval. LD in cattle is much less extensive than in a mouse population created from crossing inbred lines, and more extensive than in humans. For association mapping in Holstein-Friesian cattle, for a given design, at least one SNP is required for each 40 kb, giving a total requirement of at least 75,000 SNPs for a low power whole-genome scan (median r2 > 0.19) and up to 300,000 markers at 10 kb intervals for a high power genome scan (median r2 > 0.62). For estimation of LD by D' and Dvol with sufficient precision, a sample size of at least 400 is required, whereas for r2 a minimum sample of 75 is adequate.

  15. Movement analysis of Australian national league soccer players using global positioning system technology.

    PubMed

    Wehbe, George M; Hartwig, Timothy B; Duncan, Craig S

    2014-03-01

    Player activity profiles of match play provide valuable information for optimal athlete training prescriptions, competition strategies, and managing load and recovery and are currently lacking in elite Australian-league (A-League) soccer. The aims of the study were, therefore, to (a) determine match activity profiles for elite A-League soccer players and make match-half and positional comparisons and (b) examine the effect of situational factors including evolving match status (drawing, winning, or losing) and goals being scored and conceded on selected match activity profile variables. Global positioning system tracking devices were used to determine activity profiles of 19 elite male adult soccer players during 8 preseason matches (n = 95 files). Total distance, average speed, high-intensity running (HIR) distance, and very high-intensity running distance decreased from the first to the second half by 7.92, 9.47, 10.10, and 10.99%, respectively. Midfielders covered 11.69% more total distance, 28.08% more HIR distance, and had a 10.93% higher average speed than defenders (p ≤ 0.05; d = 1.90, 1.03, and 1.83, respectively). Attackers performed 27.50 and 30.24% less medium accelerations than defenders and midfielders, respectively (p < 0.01; d = 1.54, and 1.73). When the team was winning, average speed was 4.17% lower than when the team was drawing (p ≤ 0.05, d = 0.32). Scoring or conceding goals did not appear to affect HIR. This study adds to limited knowledge of match demands in elite A-League soccer. The match activity profiles provide descriptive benchmarks that could be used to make comparisons with other elite level soccer populations while also providing a framework for game-specific training prescription, competition strategy, and load management. The generalization that defenders experience a relatively lower match load may be questionable given their relatively high acceleration and deceleration demands.

  16. Heliocentric Distance of Coronal Mass Ejections at the Time of Energetic Particle Release: Revisiting the Ground Level Enhancement Events of Solar Cycle 23

    NASA Technical Reports Server (NTRS)

    Gopalswamy, Natchimuthuk

    2011-01-01

    Using the kinematics of coronal mass ejections (CMEs), onset time of soft X-ray flares, and the finite size of the pre-eruption CME structure, we derive the heliocentric distane at which the energetic particles during the ground level enhancement (GLE) events of Solar Cycle 23. We find that the GLE particles are released when the CMEs reach an average heliocentric distance of approx.3.25 solar radii (Rs). From this we infer that the shocks accelerating the particles are located at similar heights. Type II radio burst observations indicate that the CMEs are at much lower distances (average approx.1.4 Rs) when the CME-driven shock first forms. The shock seems to travel approx.1.8 Rs over a period of approox.30 min on the average before releasing the GLE particles. In deriving these results, we made three assumptions that have observational support: (i) the CME lift off occurs from an initial distance of about 1.25 Rs; (ii) the flare onset and CME onset are one and the same because these are two different manifestations of the same eruption; and (iii) the CME has positive acceleration from the onset to the first appearance in the coronagraphic field of view (2.5 to 6 Rs). Observations of coronal cavities in eclipse pictures and in coronagraphic images justify the assumption (i). The close relationship between the flare reconnection magnetic flux and the azimuthal flux of interplanetary magnetic clouds justify assumption (ii) consistent with the standard model (CSHKP) of solar eruption. Coronagraphic observations made close to the solar surface indicate a large positive acceleration of CMEs to a heliocentric distance of approx.3 Rs before they start slowing down due to the drag force. The inferred acceleration (approx.1.5 km/s/s) is consistent with reported values in the literature.

  17. High-density genetic mapping of a major QTL for resistance to multiple races of loose smut in a tetraploid wheat cross

    PubMed Central

    Kumar, Sachin; Knox, Ron E.; Singh, Asheesh K.; DePauw, Ron M.; Campbell, Heather L.; Isidro-Sanchez, Julio; Clarke, Fran R.; Pozniak, Curtis J.; N’Daye, Amidou; Meyer, Brad; Sharpe, Andrew; Ruan, Yuefeng; Cuthbert, Richard D.; Somers, Daryl; Fedak, George

    2018-01-01

    Loose smut, caused by Ustilago tritici (Pers.) Rostr., is a systemic disease of tetraploid durum wheat (Triticum turgidum L.). Loose smut can be economically controlled by growing resistant varieties, making it important to find and deploy new sources of resistance. Blackbird, a variety of T. turgidum L. subsp. carthlicum (Nevski) A. Love & D. Love, carries a high level of resistance to loose smut. Blackbird was crossed with the loose smut susceptible durum cultivar Strongfield to produce a doubled haploid (DH) mapping population. The parents and progenies were inoculated with U. tritici races T26, T32 and T33 individually and as a mixture at Swift Current, Canada in 2011 and 2012 and loose smut incidence (LSI) was assessed. Genotyping of the DH population and parents using an Infinium iSelect 90K single nucleotide polymorphism (SNP) array identified 12,952 polymorphic SNPs. The SNPs and 426 SSRs (previously genotyped in the same population) were mapped to 16 linkage groups spanning 3008.4 cM at an average inter-marker space of 0.2 cM in a high-density genetic map. Composite interval mapping analysis revealed three significant quantitative trait loci (QTL) for loose smut resistance on chromosomes 3A, 6B and 7A. The loose smut resistance QTL on 6B (QUt.spa-6B.2) and 7A (QUt.spa-7A.2) were derived from Blackbird. Strongfield contributed the minor QTL on 3A (QUt.spa-3A.2). The resistance on 6B was a stable major QTL effective against all individual races and the mixture of the three races; it explained up to 74% of the phenotypic variation. This study is the first attempt in durum wheat to identify and map loose smut resistance QTL using a high-density genetic map. The QTL QUt.spa-6B.2 would be an effective source for breeding resistance to multiple races of the loose smut pathogen because it provides near-complete broad resistance to the predominant virulence on the Canadian prairies. PMID:29485999

  18. Synthesis and crystalline properties of CdS incorporated polyvinylidene fluoride (PVDF) composite film

    NASA Astrophysics Data System (ADS)

    Patel, Arunendra Kumar; Sunder, Aishwarya; Mishra, Shweta; Bajpai, Rakesh

    2018-05-01

    This paper gives an insight on the synthesis and crystalline properties of Polyvinylidene Fluoride (PVDF) (host matrix) composites impregnated with Cadmium Sulphide (CdS) using Dimethyl formamide (DMF) as the base, prepared by the well known solvent casting technique. The effect of doping concentration of CdS in to the PVDF matrix was studied using X-ray diffraction technique. The structural properties like crystallinity Cr, interplanar distance d, average size of the crystalline region (D), and average inter crystalline separation (R) have been estimated for the developed composite. The crystallinity index, crystallite size and inter crystalline separation is increasing with increase in the concentration of CdS in to the PVDF matrix while the interplanar distance d is decreasing.

  19. Reduced Solar Wind Speeds at New Horizons Beyond 30 AU

    NASA Astrophysics Data System (ADS)

    Elliott, H. A.; McComas, D. J.; Zirnstein, E.; Delamere, P. A.; Bagenal, F.; Stern, A.; Weaver, H. A., Jr.; Young, L. A.; Ennico Smith, K.; Olkin, C.

    2017-12-01

    Prior comparisons between Voyager 2 and IMP 8 observations found the solar wind had clearly decrease by 8% at a distance of 25 AU. Since mid-2016 solar rotation averaged speeds at New Horizons have been elevated relative to speeds observed in 2014 and 2015. However, we find a clear decrease in the New Horizons speeds beyond 30 AU when compared to those of ACE near Earth. At distances between 30-38.5 AU the relative speed reduction is in the 8-11% range. We will further this work by also comparing with available STEREO observations. By including STEREO, we can assess how sensitive the speed comparisons are to longitude separations and determine the appropriate time scale to average over.

  20. The Molecular Structure of cis-FONO

    NASA Technical Reports Server (NTRS)

    Lee, Timothy J.; Dateo, Christopher E.; Rice, Julia E.; Langhoff, Stephen R. (Technical Monitor)

    1994-01-01

    The molecular structure of cis-FONO has been determined with the CCSD(T) correlation method using an spdf quality basis set. In agreement with previous coupled-cluster calculations but in disagreement with density functional theory, cis-FONO is found to exhibit normal bond distances. The quadratic and cubic force fields of cis-FONO have also been determined in order to evaluate the effect of vibrational averaging on the molecular geometry. Vibrational averaging is found to increase bond distances, as expected, but it does not affect the qualitative nature of the bonding. The CCSD(T)/spdf harmonic frequencies of cis-FONO support our previous assertion that a band observed at 1200 /cm is a combination band (upsilon(sub 3) + upsilon(sub 4)), and not a fundamental.

  1. Structure of air shower disc near the core

    NASA Technical Reports Server (NTRS)

    Inoue, N.; Kawamoto, M.; Misaki, Y.; Maeda, T.; Takeuchi, T.; Toyoda, Y.

    1985-01-01

    The longitudinal structure of the air shower disk is studied by measuring the arrival time distributions of air shower particles for showers with electron size in the range 3.2 x 10 to the 5.5. power to 3.2 x 10 to the 7.5 power in the Akeno air-shower array (930 gcm squared atmospheric depth). The average FWHM as a parameter of thickness of air shower disk increases with core distances at less than 50m. AT the present stage, dependence on electron size, zenith angle and air shower age is not apparent. The average thickness of the air shower disk within a core distance of 50m could be determined by an electromagnetic cascade starting from the lower altitude.

  2. 46 CFR 163.002-21 - Approval tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... raised and lowered under power operation until a total distance of at least 150 meters (500 feet) has... least 5 meters (16 feet). The average speed of raising the ladder or lift platform and the average lowering speed during this test must both be between 15 and 21 meters per minute (50 and 70 feet per minute...

  3. The effect of sensor sheltering and averaging techniques on wind measurements at the Shuttle Landing Facility

    NASA Technical Reports Server (NTRS)

    Merceret, Francis J.

    1995-01-01

    This document presents results of a field study of the effect of sheltering of wind sensors by nearby foliage on the validity of wind measurements at the Space Shuttle Landing Facility (SLF). Standard measurements are made at one second intervals from 30-feet (9.1-m) towers located 500 feet (152 m) from the SLF centerline. The centerline winds are not exactly the same as those measured by the towers. A companion study, Merceret (1995), quantifies the differences as a function of statistics of the observed winds and distance between the measurements and points of interest. This work examines the effect of nearby foliage on the accuracy of the measurements made by any one sensor, and the effects of averaging on interpretation of the measurements. The field program used logarithmically spaced portable wind towers to measure wind speed and direction over a range of conditions as a function of distance from the obstructing foliage. Appropriate statistics were computed. The results suggest that accurate measurements require foliage be cut back to OFCM standards. Analysis of averaging techniques showed that there is no significant difference between vector and scalar averages. Longer averaging periods reduce measurement error but do not otherwise change the measurement in reasonably steady flow regimes. In rapidly changing conditions, shorter averaging periods may be required to capture trends.

  4. Calculation of Resistive Loads for Elastic Resistive Exercises.

    PubMed

    Picha, Kelsey; Uhl, Tim

    2018-03-14

    What is the correct resistive load to start resistive training with elastic resistance to gain strength? This question is typically answered by the clinician's best estimate and patient's level of discomfort without objective evidence. To determine the average level of resistance to initiate a strengthening routine with elastic resistance following isometric strength testing. Cohort. Clinical. 34 subjects (31 ± 13 y, 73 ± 17 kg, 170 ± 12 cm). The force produced was measured in Newtons (N) with an isometric dynamometer. The force distance was the distance from center of joint to location of force applied was measured in meters to calculate torque that was called "Test Torque" for the purposes of this report. This torque data was converted to "Exercise Load" in pounds based on the location where the resistance was applied, specifically the distance away from the center of rotation of the exercising limb. The average amount of exercise load as percentage of initial Test Torque for each individual for each exercise was recorded to determine what the average level of resistance that could be used for elastic resistance strengthening program. The percentage of initial test torque calculated for the exercise was recorded for each exercise and torque produced was normalized to body weight. The average percentage of maximal isometric force that was used to initiate exercises was 30 ± 7% of test torque. This provides clinicians with an objective target load to start elastic resistance training. Individual variations will occur but utilization of a load cell during elastic resistance provides objective documentation of exercise progression.

  5. Two-laser optical distance-measuring instrument that corrects for the atmospheric index of refraction.

    NASA Technical Reports Server (NTRS)

    Earnshaw, K. B.; Hernandez, E. N.

    1972-01-01

    The Wave Propagation Laboratory of the Environmental Research Laboratories of the National Oceanic and Atmospheric Administration has been engaged in the development of dual-wavelength, optical distance-measuring instruments. Recently a new generation of this type of high-accuracy instrument has been completed. Preliminary testing of the new instrument indicates that the original goal of the project, accuracy of better than one part in a million over distances of 5-10 km using averaging times of less than 1 min, is being met. This paper describes the instrument and preliminary test results.

  6. Propagation of a cosh-Gaussian beam through an optical system in turbulent atmosphere.

    PubMed

    Chu, Xiuxiang

    2007-12-24

    The propagation of a cosh-Gaussian beam through an arbitrary ABCD optical system in turbulent atmosphere has been investigated. The analytical expressions for the average intensity at any receiver plane are obtained. As an elementary example, the average intensity and its radius at the image plane of a cosh-Gaussian beam through a thin lens are studied. To show the effects of a lens on the average intensity and the intensity radius of the laser beam in turbulent atmosphere, the properties of a collimated cosh-Gaussian beam and a focused cosh-Gaussian beam for direct propagation in turbulent atmosphere are studied and numerically calculated. The average intensity profiles of a cosh-Gaussian beam through a lens can have a shape similar to that of the initial beam for a longer propagation distance than that of a collimated cosh-Gaussian beam for direct propagation. With the increment in the propagation distance, the average intensity radius at the image plane of a cosh-Gaussian beam through a thin lens will be smaller than that at the focal plane of a focused cosh-Gaussian beam for direct propagation. Meanwhile, the intensity distributions at the image plane of a cosh-Gaussian beam through a lens with different w(0) and Omega(0) are also studied.

  7. Pilot study for quantifying driving characteristics during power wheelchair soccer.

    PubMed

    Kumar, Amit; Karmarkar, Amol M; Collins, Diane M; Souza, Ana; Oyster, Michelle L; Cooper, Rosemarie; Cooper, Rory A

    2012-01-01

    This study determined the driving characteristics of wheelchair users during power wheelchair soccer games. Data for this study were collected at the 28th and 29th National Veterans Wheelchair Games. Nineteen veterans who were 18 years or older and power wheelchair soccer players completed a brief demographic survey and provided information about their power wheelchairs. A customized data-logging device was placed on each participant's wheelchair before power soccer game participation. The data logger was removed at the end of the final game for each participant. The average distance traveled during the games was 899.5 +/- 592.5 m, and the average maximum continuous distance traveled was 256.0 +/- 209.4 m. The average wheelchair speed was 0.8 +/- 0.2 m/s, and the average duration of driving time was 17.6 +/- 8.3 min. Average proportion of time spent at a speed >1 m/s was 30.7% +/- 33.8%, between 0.5 and 1 m/s was 16.2% +/- 34.4%, and <0.5 m/s was 21.4% +/- 24.3%. The information from this descriptive study provides insight for future research in the field of adapted sports for people with high levels of impairments who use power wheelchairs for their mobility.

  8. Quiet-time magnetospheric field depression at 2.3 to 3.6 R sub E

    NASA Technical Reports Server (NTRS)

    Sugiura, M.

    1972-01-01

    Fluxgate magnetometer data obtained by OGO-5 near perigee were used to establish the existence of large field depressions in the magnetosphere under conditions of varying degree of disturbance at distances ranging from 2.3 to 3.6 R sub E at all local times. The results also provide the average delta B at these distances when Dst, as being derived at present, is zero.

  9. Cycle-time equation for the Koller K300 cable yarder operating on steep slopes in the Northeast

    Treesearch

    Neil K. Huyler; Chris B. LeDoux

    1997-01-01

    Describes a delay-free-cycle time equation for the Koller K300 skyline yarder operating on steep slopes in the Northeast. Using the equation, the average delay-free-cycle time was 5.72 minutes. This means that about 420 cubic feet of material per hour can be produced. The important variables used in the equation were slope yarding distance, lateral yarding distance,...

  10. Guiding of Plasmons and Phonons in Complex Three Dimensional Structures

    DTIC Science & Technology

    2013-01-01

    typical sample. We employed X - ray diffraction (XRD) to measure the average grain size across the entire depth of the sample over spot sizes Figure...propagation distance L as the 1/e decay length of the field intensity along x ...as well as the network layout with subwavelegth gap size and internode distance on the order of the effective wavelength, a small 2 x 2 resonant

  11. Determination of safety distance limits for a human near a cellular base station antenna, adopting the IEEE standard or ICNIRP guidelines.

    PubMed

    Cooper, Justin; Marx, Bernd; Buhl, Johannes; Hombach, Volker

    2002-09-01

    This paper investigates the minimum distance for a human body in the near field of a cellular telephone base station antenna for which there is compliance with the IEEE or ICNIRP threshold values for radio frequency electromagnetic energy absorption in the human body. First, local maximum specific absorption rates (SARs), measured and averaged over volumes equivalent to 1 and to 10 g tissue within the trunk region of a physical, liquid filled shell phantom facing and irradiated by a typical GSM 900 base station antenna, were compared to corresponding calculated SAR values. The calculation used a homogeneous Visible Human body model in front of a simulated base station antenna of the same type. Both real and simulated base station antennas operated at 935 MHz. Antenna-body distances were between 1 and 65 cm. The agreement between measurements and calculations was excellent. This gave confidence in the subsequent calculated SAR values for the heterogeneous Visible Human model, for which each tissue was assigned the currently accepted values for permittivity and conductivity at 935 MHz. Calculated SAR values within the trunk of the body were found to be about double those for the homogeneous case. When the IEEE standard and the ICNIRP guidelines are both to be complied with, the local SAR averaged over 1 g tissue was found to be the determining parameter. Emitted power values from the antenna that produced the maximum SAR value over 1 g specified in the IEEE standard at the base station are less than those needed to reach the ICNIRP threshold specified for the local SAR averaged over 10 g. For the GSM base station antenna investigated here operating at 935 MHz with 40 W emitted power, the model indicates that the human body should not be closer to the antenna than 18 cm for controlled environment exposure, or about 95 cm for uncontrolled environment exposure. These safe distance limits are for SARs averaged over 1 g tissue. The corresponding safety distance limits under the ICNIRP guidelines for SAR taken over 10 g tissue are 5 cm for occupational exposure and about 75 cm for general-public exposure. Copyright 2002 Wiley-Liss, Inc.

  12. Time-motion analysis of goalball players in attacks: differences of the player positions and the throwing techniques.

    PubMed

    Monezi, Lucas Antônio; Magalhães, Thiago Pinguelli; Morato, Márcio Pereira; Mercadante, Luciano Allegretti; Furtado, Otávio Luis Piva da Cunha; Misuta, Milton Shoiti

    2018-03-26

    In this study, we aimed to analyse goalball players time-motion variables (distance covered, time spent, maximum and average velocities) in official goalball match attacks, taking into account the attack phases (preparation and throwing), player position (centres and wings) and throwing techniques (frontal, spin and between the legs). A total of 365 attacks were assessed using a video based method (2D) through manual tracking using the Dvideo system. Inferential non-parametric statistics were applied for comparison of preparation vs. throwing phase, wings vs. centres and, among the throwing techniques, frontal, spin and between the legs. Significant differences were found between the attack preparation versus the throwing phase for all player time-motion variables: distance covered, time spent, maximum player velocity and average player velocity. Wing players performed most of the throws (85%) and covered longer distances than centres (1.65 vs 0.31 m). The between the legs and the spin throwing techniques presented greater values for most of the time-motion variables (distance covered, time spent and maximum player velocity) than did the frontal technique in both attack phases. These findings provide important information regarding players' movement patterns during goalball matches that can be used to plan more effective training.

  13. Corrected Integral Shape Averaging Applied to Obstructive Sleep Apnea Detection from the Electrocardiogram

    NASA Astrophysics Data System (ADS)

    Boudaoud, S.; Rix, H.; Meste, O.; Heneghan, C.; O'Brien, C.

    2007-12-01

    We present a technique called corrected integral shape averaging (CISA) for quantifying shape and shape differences in a set of signals. CISA can be used to account for signal differences which are purely due to affine time warping (jitter and dilation/compression), and hence provide access to intrinsic shape fluctuations. CISA can also be used to define a distance between shapes which has useful mathematical properties; a mean shape signal for a set of signals can be defined, which minimizes the sum of squared shape distances of the set from the mean. The CISA procedure also allows joint estimation of the affine time parameters. Numerical simulations are presented to support the algorithm for obtaining the CISA mean and parameters. Since CISA provides a well-defined shape distance, it can be used in shape clustering applications based on distance measures such as[InlineEquation not available: see fulltext.]-means. We present an application in which CISA shape clustering is applied to P-waves extracted from the electrocardiogram of subjects suffering from sleep apnea. The resulting shape clustering distinguishes ECG segments recorded during apnea from those recorded during normal breathing with a sensitivity of[InlineEquation not available: see fulltext.] and specificity of[InlineEquation not available: see fulltext.].

  14. Establishing an efficient way to utilize the drought resistance germplasm population in wheat.

    PubMed

    Wang, Jiancheng; Guan, Yajing; Wang, Yang; Zhu, Liwei; Wang, Qitian; Hu, Qijuan; Hu, Jin

    2013-01-01

    Drought resistance breeding provides a hopeful way to improve yield and quality of wheat in arid and semiarid regions. Constructing core collection is an efficient way to evaluate and utilize drought-resistant germplasm resources in wheat. In the present research, 1,683 wheat varieties were divided into five germplasm groups (high resistant, HR; resistant, R; moderate resistant, MR; susceptible, S; and high susceptible, HS). The least distance stepwise sampling (LDSS) method was adopted to select core accessions. Six commonly used genetic distances (Euclidean distance, Euclid; Standardized Euclidean distance, Seuclid; Mahalanobis distance, Mahal; Manhattan distance, Manhat; Cosine distance, Cosine; and Correlation distance, Correlation) were used to assess genetic distances among accessions. Unweighted pair-group average (UPGMA) method was used to perform hierarchical cluster analysis. Coincidence rate of range (CR) and variable rate of coefficient of variation (VR) were adopted to evaluate the representativeness of the core collection. A method for selecting the ideal constructing strategy was suggested in the present research. A wheat core collection for the drought resistance breeding programs was constructed by the strategy selected in the present research. The principal component analysis showed that the genetic diversity was well preserved in that core collection.

  15. Magnetic field directional discontinuities - Characteristics between 0.46 and 1.0 AU

    NASA Technical Reports Server (NTRS)

    Lepping, R. P.; Behannon, K. W.

    1986-01-01

    Based on Mariner 10 data, a statistical survey and an application of the Sonnerup-Cahill variance procedure to a visual identification with 1.2-s averages for time intervals corresponding to the equally spaced heliocentric distances of 1.0, 0.72 and 0.46 AU, are employed to study the characteristics of directional discontinuities (DDs) in the interplanetary magnetic field. Analysis using two methods demonstrated that the ratio of tangential discontinuities (TDs) to rotational discontinuities (RDs) decreased with decreasing radial distance. Decreases in average discontinuity thickness of 41 percent between 1.0 and 0.72 AU, and 56 percent between 1.0 and 0.46 AU, were found for both TDs and RDs, in agreement with Pioneer 10 data between 1 and 5 AU. Normalization of the individual DD thicknesses with respect to the estimated local proton gyroradius (R sub L) gave a nearly constant average thickness at the three locations, 36 + or - 5 R sub L, for both RDs and TDs.

  16. Quantifying exciton hopping in disordered media with quenching sites: Application to arrays of quantum dots

    NASA Astrophysics Data System (ADS)

    Miyazaki, Jun

    2013-10-01

    We present an analytical method for quantifying exciton hopping in an energetically disordered system with quenching sites. The method is subsequently used to provide a quantitative understanding of exciton hopping in a quantum dot (QD) array. Several statistical quantities that characterize the dynamics (survival probability, average number of distinct sites visited, average hopping distance, and average hopping rate in the initial stage) are obtained experimentally by measuring time-resolved fluorescence intensities at various temperatures. The time evolution of these quantities suggests in a quantitative way that at low temperature an exciton tends to be trapped at a local low-energy site, while at room temperature, exciton hopping occurs repeatedly, leading to a large hopping distance. This method will serve to facilitate highly efficient optoelectronic devices using QDs such as photovoltaic cells and light-emitting diodes, since exciton hopping is considered to strongly influence their operational parameters. The presence of a dark QD (quenching site) that exhibits fast decay is also quantified.

  17. The locomotor activity of soccer players based on playing positions during the 2010 World Cup.

    PubMed

    Soroka, Andrzej

    2018-06-01

    The aim of this study was to define the locomotor activity of footballer players during the 2010 World Cup and to assess what differences existed among different playing positions. Research was conducted using research material collected from the Castrol Performance Index, a kinematic game analysis system that records player movements during a game by use of semi-automatic cameras. A total of 599 players who participated in the championships were analyzed. The results were evaluated using one-way analysis of variance (ANOVA) and a post-hoc test that calculated the Honestly Significant Difference (HSD) in order to determine which mean values significantly differed among the player positions. It was found that midfielders covered on average the largest distance during a match (10,777.6 m, P<0.001) as well as performing the most locomotor activity at high and sprint intensities (2936.8 m and 108.4 m, respectively). Additionally, midfielders also spent the largest amount of time at performing at a high intensity (10.6%). Strikers also featured high levels of the above parameters; the total length of distance covered with high intensities was found to be on average 2586.7 m, the distance covered at sprint intensity was 105 m. The footballers, playing at the championship level feature excellent locomotor preparation. This fact is undoubtedly supported by the aerobic training of high intensity. Such training allows footballers to extend the distance they cover during the match, increase the intensity of locomotor activities and sprint speed distance.

  18. Solar wind velocity and temperature in the outer heliosphere

    NASA Technical Reports Server (NTRS)

    Gazis, P. R.; Barnes, A.; Mihalov, J. D.; Lazarus, A. J.

    1994-01-01

    At the end of 1992, the Pioneer 10, Pioneer 11, and Voyager 2 spacecraft were at heliocentric distances of 56.0, 37.3, and 39.0 AU and heliographic latitudes of 3.3 deg N, 17.4 deg N, and 8.6 deg S, respectively. Pioneer 11 and Voyager 2 are at similar celestial longitudes, while Pioneer 10 is on the opposite side of the Sun. All three spacecraft have working plasma analyzers, so intercomparison of data from these spacecraft provides important information about the global character of the solar wind in the outer heliosphere. The averaged solar wind speed continued to exhibit its well-known variation with solar cycle: Even at heliocentric distances greater than 50 AU, the average speed is highest during the declining phase of the solar cycle and lowest near solar minimum. There was a strong latitudinal gradient in solar wind speed between 3 deg and 17 deg N during the last solar minimum, but this gradient has since disappeared. The solar wind temperature declined with increasing heliocentric distance out to a heliocentric distance of at least 20 AU; this decline appeared to continue at larger heliocentric distances, but temperatures in the outer heliosphere were suprisingly high. While Pioneer 10 and Voyager 2 observed comparable solar wind temperatures, the temperature at Pioneer 11 was significantly higher, which suggests the existence of a large-scale variation of temperature with heliographic longitude. There was also some suggestion that solar wind temperatures were higher near solar minimum.

  19. Evening flights of female northern pintails from a major roost site

    USGS Publications Warehouse

    Cox, R.R.; Afton, A.D.

    1996-01-01

    We monitored evening flights of female Northern Pintails (Anas acuta) from Lacassine National Wildlife Refuge (NWR) in southwestern Louisiana during winters of 1991-1992 and 1992-1993. We analyzed the influence of female age, winter, and date within wintering period on three flight parameters: distance, duration, and departure time. Flight distance and duration increased with date within wintering period, and age differences in flight distance and duration were not consistent between winters. Females departed 12 min later, on average, on clear, moonlit evenings than on overcast, moonless evenings, and 4 min later when winds were light rather than heavy. After controlling for variation due to environmental conditions, immature females departed Lacassine NWR 1.3 min earlier, on average, than did adults. Flight parameters of females did not differ between hunting and non-hunting time periods. Estimated daily transit costs ranged from 27-54% of basal metabolic rate, 7-19% of daily energy expenditure, and 8-20% of daily dietary intake of rice (Oryza sativa). Our findings that flight distance and duration increased with date within wintering period were consistent with predictions of refuging theory, but alternative hypotheses also could explain these results. Evening flights of Northern Pintails roosting on Lacassine NWR were greater in distance and duration than those reported for most other species of wintering waterfowl. We recommend that proximity of refuges to feeding sites be considered in conservation and management plans for wintering Northern Pintails and other refuging waterfowl.

  20. Global Positioning System Use in the Community to Evaluate Improvements in Walking After Revascularization

    PubMed Central

    Gernigon, Marie; Le Faucheur, Alexis; Fradin, Dominique; Noury-Desvaux, Bénédicte; Landron, Cédric; Mahe, Guillaume; Abraham, Pierre

    2015-01-01

    Abstract Revascularization aims at improving walking ability in patients with arterial claudication. The highest measured distance between 2 stops (highest-MDCW), the average walking speed (average-WSCW), and the average stop duration (average-DSCW) can be measured by global positioning system, but their evolution after revascularization is unknown. We included 251 peripheral artery diseased patients with self-reported limiting claudication. The patients performed a 1-hour stroll, recorded by a global positioning system receiver. Patients (n = 172) with confirmed limitation (highest-MDCW <2000m) at inclusion were reevaluated after 6 months. Patients revascularized during the follow-up period were compared with reference patients (ie, with unchanged lifestyle medical or surgical status). Other patients (lost to follow-up or treatment change) were excluded (n = 89). We studied 44 revascularized and 39 reference patients. Changes in highest-MDCW (+442 vs. +13 m) and average-WSCW (+0.3 vs. −0.2 km h−1) were greater in revascularized than in reference patients (both P < 0.01). In contrast, no significant difference in average-DSCW changes was found between the groups. Among the revascularized patients, 13 (29.5%) had a change in average-WSCW, but not in highest-MDCW, greater than the mean + 1 standard deviation of the change observed for reference patients. Revascularization may improve highest-MDCW and/or average-WSCW. This first report of changes in community walking ability in revascularized patients suggests that, beyond measuring walking distances, average-WSCW measurement is essential to monitor these changes. Applicability to other surgical populations remains to be evaluated. Registration: http://www.clinicaltrials.gov/ct2/show/NCT01141361 PMID:25950694

  1. Global positioning system use in the community to evaluate improvements in walking after revascularization: a prospective multicenter study with 6-month follow-up in patients with peripheral arterial disease.

    PubMed

    Gernigon, Marie; Le Faucheur, Alexis; Fradin, Dominique; Noury-Desvaux, Bénédicte; Landron, Cédric; Mahe, Guillaume; Abraham, Pierre

    2015-05-01

    Revascularization aims at improving walking ability in patients with arterial claudication. The highest measured distance between 2 stops (highest-MDCW), the average walking speed (average-WSCW), and the average stop duration (average-DSCW) can be measured by global positioning system, but their evolution after revascularization is unknown.We included 251 peripheral artery diseased patients with self-reported limiting claudication. The patients performed a 1-hour stroll, recorded by a global positioning system receiver. Patients (n = 172) with confirmed limitation (highest-MDCW <2000m) at inclusion were reevaluated after 6 months. Patients revascularized during the follow-up period were compared with reference patients (ie, with unchanged lifestyle medical or surgical status). Other patients (lost to follow-up or treatment change) were excluded (n = 89).We studied 44 revascularized and 39 reference patients. Changes in highest-MDCW (+442 vs. +13 m) and average-WSCW (+0.3 vs. -0.2 km h) were greater in revascularized than in reference patients (both P < 0.01). In contrast, no significant difference in average-DSCW changes was found between the groups. Among the revascularized patients, 13 (29.5%) had a change in average-WSCW, but not in highest-MDCW, greater than the mean + 1 standard deviation of the change observed for reference patients.Revascularization may improve highest-MDCW and/or average-WSCW. This first report of changes in community walking ability in revascularized patients suggests that, beyond measuring walking distances, average-WSCW measurement is essential to monitor these changes. Applicability to other surgical populations remains to be evaluated. http://www.clinicaltrials.gov/ct2/show/NCT01141361.

  2. Metabolic power and energetic costs of professional Australian Football match-play.

    PubMed

    Coutts, Aaron J; Kempton, Thomas; Sullivan, Courtney; Bilsborough, Johann; Cordy, Justin; Rampinini, Ermanno

    2015-03-01

    To compare the metabolic power demands between positional groups, and examine temporal changes in these parameters during Australian Football match-play. Longitudinal observational study. Global positioning system data were collected from 39 Australian Football players from the same club during 19 Australian Football League competition games over two seasons. A total of 342 complete match samples were obtained for analysis. Players were categorised into one of six positional groups: tall backs, mobile backs, midfielders, tall forwards, mobile forwards and rucks. Instantaneous raw velocity data obtained from the global positioning system units was exported to a customised spreadsheet which provided estimations of both speed-based (e.g. total and high-speed running distance) and derived metabolic power and energy expenditure variables (e.g. average metabolic power, high-power distance, total energy expenditure). There were significant differences between positional groups for both speed-based and metabolic power indices, with midfielders covering more total and high-speed distance, as well as greater average and overall energy expenditure compared to other positions (all p<0.001). There were reductions in total, high-speed, and high-power distance, as well as average metabolic power throughout the match (all p<0.001). Positional differences exist for both metabolic power and traditional running based variables. Generally, midfielders, followed by mobile forwards and mobile backs had greater activity profiles compared to other position groups. We observed that the reductions in most metabolic power variables during the course of the match are comparable to traditional running based metrics. This study demonstrates that metabolic power data may contribute to our understanding of the physical demands of Australian Football. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  3. Match-play activity profile in professional soccer players during official games and the relationship between external and internal load.

    PubMed

    Suarez-Arrones, L; Torreño, N; Requena, B; Sáez De Villarreal, E; Casamichana, D; Barbero-Alvarez, J C; Munguía-Izquierdo, D

    2015-12-01

    The aim was to quantify for the first time the physical and physiological profile of professional soccer players in official games using GPS and heart rate (HR) response. Thirty professional soccer players were investigated during a half in competitive club level matches (N.=348) using GPS devices. The relative total distance was 118.9±10.7 m∙min(-1) and player's Work-To-Rest Ratio was 2.1:1. Defenders covered the lowest total distance, while Second-Strikers (2(nd)S) and Wide-Midfielders (W-MD) traveled the greatest total distance. Defenders presented the lowest Work-To-Rest Ratio values. Playing position also impacted on all sprinting performance results, except in average sprint distance and time of sprint. The number of sprints and repeated-sprint sequences recorded by the W-MD and Strikers (S) were significantly greater than any other group. The average HR recorded was 87.1%HRmax and the relationship between the external and internal load value (Effindex) was 1.4 with significant differences in both between playing positions. W-MD recorded a significantly smaller average HR than any other group and Centre-Backs showed a significantly smaller Effindex value than any other group. Conversely, W-MD showed a significantly greater Effindex value than any other group, except the 2(nd)S. This study has verified a number of statistically significant differences between the different playing positions. Coaches should be focused on the specific physical and physiological requirements of the playing positions to optimize the training prescription in soccer. The relationships between external and internal load measures among position-specific indicates that players with less overall running performance during match-play were the worst in Effindex.

  4. On the construction of a time base and the elimination of averaging errors in proxy records

    NASA Astrophysics Data System (ADS)

    Beelaerts, V.; De Ridder, F.; Bauwens, M.; Schmitz, N.; Pintelon, R.

    2009-04-01

    Proxies are sources of climate information which are stored in natural archives (e.g. ice-cores, sediment layers on ocean floors and animals with calcareous marine skeletons). Measuring these proxies produces very short records and mostly involves sampling solid substrates, which is subject to the following two problems: Problem 1: Natural archives are equidistantly sampled at a distance grid along their accretion axis. Starting from these distance series, a time series needs to be constructed, as comparison of different data records is only meaningful on a time grid. The time series will be non-equidistant, as the accretion rate is non-constant. Problem 2: A typical example of sampling solid substrates is drilling. Because of the dimensions of the drill, the holes drilled will not be infinitesimally small. Consequently, samples are not taken at a point in distance, but rather over a volume in distance. This holds for most sampling methods in solid substrates. As a consequence, when the continuous proxy signal is sampled, it will be averaged over the volume of the sample, resulting in an underestimation of the amplitude. Whether this averaging effect is significant, depends on the volume of the sample and the variations of interest of the proxy signal. Starting from the measured signal, the continuous signal needs to be reconstructed in order eliminate these averaging errors. The aim is to provide an efficient identification algorithm to identify the non-linearities in the distance-time relationship, called time base distortions, and to correct for the averaging effects. Because this is a parametric method, an assumption about the proxy signal needs to be made: the proxy record on a time base is assumed to be harmonic, this is an obvious assumption because natural archives often exhibit a seasonal cycle. In a first approach the averaging effects are assumed to be in one direction only, i.e. the direction of the axis on which the measurements were performed. The measured averaged proxy signal is modeled by following signal model: -- Δ ∫ n+12Δδ- y(n,θ) = δ- 1Δ- y(m,θ)dm n-2 δ where m is the position, x(m) = Δm; θ are the unknown parameters and y(m,θ) is the proxy signal we want to identify (the proxy signal as found in the natural archive), which we model as: y(m, θ) = A +∑H [A sin(kωt(m ))+ A cos(kωt(m ))] 0 k=1 k k+H With t(m): t(m) = mTS + g(m )TS Here TS = 1/fS is the sampling period, fS the sampling frequency, and g(m) the unknown time base distortion (TBD). In this work a splines approximation of the TBD is chosen: ∑ g(m ) = b blφl(m ) l=1 where, b is a vector of unknown time base distortion parameters, and φ is a set of splines. The estimates of the unknown parameters were obtained with a nonlinear least squares algorithm. The vessel density measured in the mangrove tree R mucronata was used to illustrate the method. The vessel density is a proxy for the rain fall in tropical regions. The proxy data on the newly constructed time base showed a yearly periodicity, this is what we expected and the correction for the averaging effect increased the amplitude by 11.18%.

  5. Optimizing deep hyperthermia treatments: are locations of patient pain complaints correlated with modelled SAR peak locations?

    NASA Astrophysics Data System (ADS)

    Canters, R. A. M.; Franckena, M.; van der Zee, J.; van Rhoon, G. C.

    2011-01-01

    During deep hyperthermia treatment, patient pain complaints due to heating are common when maximizing power. Hence, there exists a good rationale to investigate whether the locations of predicted SAR peaks by hyperthermia treatment planning (HTP) are correlated with the locations of patient pain during treatment. A retrospective analysis was performed, using the treatment reports of 35 patients treated with deep hyperthermia controlled by extensive treatment planning. For various SAR indicators, the average distance from a SAR peak to a patient discomfort location was calculated, for each complaint. The investigated V0.1 closest (i.e. the part of the 0.1th SAR percentile closest to the patient complaint) performed the best, and leads to an average distance between the SAR peak and the complaint location of 3.9 cm. Other SAR indicators produced average distances that were all above 10 cm. Further, the predicted SAR peak location with V0.1 provides a 77% match with the region of complaint. The current study demonstrates that HTP is able to provide a global indication of the regions where hotspots during treatment will most likely occur. Further development of this technology is necessary in order to use HTP as a valuable toll for objective and advanced SAR steering. The latter is especially valid for applications that enable 3D SAR steering.

  6. Emission characteristics of offshore fishing ships in the Yellow Bo Sea, China.

    PubMed

    Liu, Yingshuai; Ge, Yunshan; Tan, Jianwei; Fu, Mingliang; Shah, Asad Naeem; Li, Luqiang; Ji, Zhe; Ding, Yan

    2018-03-01

    Maritime transport has been playing a decisive role in global trade. Its contribution to the air pollution of the sea and coastal areas has been widely recognized. The air pollutant emission inventories of several harbors in China have already been established. However, the emission factors of local ships have not been addressed comprehensively, and thus are lacking from the emission inventories. In this study, on-board emission tests of eight diesel-powered offshore fishing ships were conducted near the coastal region of the northern Yellow Bo Sea fishing ground of Dalian, China. Results show that large amounts of fine particles (<0.5μm, 90%) were found in maneuvering mode, which were about five times higher than those during cruise mode. Emission rates as well as emission factors based on both distance and fuel were determined during the cruise and maneuvering modes (including departure and arrival). Average emission rates and distance-based emission factors of CO, HC and PM were much higher during the maneuvering mode as compared with the cruise mode. However, the average emission rate of Nitrous Oxide (NO x ) was higher during the cruise mode as compared with the maneuvering modes. On the contrary, the average distance-based emission factors of NO x were lower during the cruise mode relative to the maneuvering mode due to the low sailing speed of the latter. Copyright © 2017. Published by Elsevier B.V.

  7. Extraction of liver volumetry based on blood vessel from the portal phase CT dataset

    NASA Astrophysics Data System (ADS)

    Maklad, Ahmed S.; Matsuhiro, Mikio; Suzuki, Hidenobu; Kawata, Yoshiki; Niki, Noboru; Utsunomiya, Tohru; Shimada, Mitsuo

    2012-02-01

    At liver surgery planning stage, the liver volumetry would be essential for surgeons. Main problem at liver extraction is the wide variability of livers in shapes and sizes. Since, hepatic blood vessels structure varies from a person to another and covers liver region, the present method uses that information for extraction of liver in two stages. The first stage is to extract abdominal blood vessels in the form of hepatic and nonhepatic blood vessels. At the second stage, extracted vessels are used to control extraction of liver region automatically. Contrast enhanced CT datasets at only the portal phase of 50 cases is used. Those data include 30 abnormal livers. A reference for all cases is done through a comparison of two experts labeling results and correction of their inter-reader variability. Results of the proposed method agree with the reference at an average rate of 97.8%. Through application of different metrics mentioned at MICCAI workshop for liver segmentation, it is found that: volume overlap error is 4.4%, volume difference is 0.3%, average symmetric distance is 0.7 mm, Root mean square symmetric distance is 0.8 mm, and maximum distance is 15.8 mm. These results represent the average of overall data and show an improved accuracy compared to current liver segmentation methods. It seems to be a promising method for extraction of liver volumetry of various shapes and sizes.

  8. The fundamentals of average local variance--Part II: Sampling simple regular patterns with optical imagery.

    PubMed

    Bøcher, Peder Klith; McCloy, Keith R

    2006-02-01

    In this investigation, the characteristics of the average local variance (ALV) function is investigated through the acquisition of images at different spatial resolutions of constructed scenes of regular patterns of black and white squares. It is shown that the ALV plot consistently peaks at a spatial resolution in which the pixels has a size corresponding to half the distance between scene objects, and that, under very specific conditions, it also peaks at a spatial resolution in which the pixel size corresponds to the whole distance between scene objects. It is argued that the peak at object distance when present is an expression of the Nyquist sample rate. The presence of this peak is, hence, shown to be a function of the matching between the phase of the scene pattern and the phase of the sample grid, i.e., the image. When these phases match, a clear and distinct peak is produced on the ALV plot. The fact that the peak at half the distance consistently occurs in the ALV plot is linked to the circumstance that the sampling interval (distance between pixels) and the extent of the sampling unit (size of pixels) are equal. Hence, at twice the Nyquist sampling rate, each fundamental period of the pattern is covered by four pixels; therefore, at least one pixel is always completely embedded within one pattern element, regardless of sample scene phase. If the objects in the scene are scattered with a distance larger than their extent, the peak will be related to the size by a factor larger than 1/2. This is suggested to be the explanation to the results presented by others that the ALV plot is related to scene-object size by a factor of 1/2-3/4.

  9. Criterion validity and accuracy of global positioning satellite and data logging devices for wheelchair tennis court movement

    PubMed Central

    Sindall, Paul; Lenton, John P.; Whytock, Katie; Tolfrey, Keith; Oyster, Michelle L.; Cooper, Rory A.; Goosey-Tolfrey, Victoria L.

    2013-01-01

    Purpose To compare the criterion validity and accuracy of a 1 Hz non-differential global positioning system (GPS) and data logger device (DL) for the measurement of wheelchair tennis court movement variables. Methods Initial validation of the DL device was performed. GPS and DL were fitted to the wheelchair and used to record distance (m) and speed (m/second) during (a) tennis field (b) linear track, and (c) match-play test scenarios. Fifteen participants were monitored at the Wheelchair British Tennis Open. Results Data logging validation showed underestimations for distance in right (DLR) and left (DLL) logging devices at speeds >2.5 m/second. In tennis-field tests, GPS underestimated distance in five drills. DLL was lower than both (a) criterion and (b) DLR in drills moving forward. Reversing drill direction showed that DLR was lower than (a) criterion and (b) DLL. GPS values for distance and average speed for match play were significantly lower than equivalent values obtained by DL (distance: 2816 (844) vs. 3952 (1109) m, P = 0.0001; average speed: 0.7 (0.2) vs. 1.0 (0.2) m/second, P = 0.0001). Higher peak speeds were observed in DL (3.4 (0.4) vs. 3.1 (0.5) m/second, P = 0.004) during tennis match play. Conclusions Sampling frequencies of 1 Hz are too low to accurately measure distance and speed during wheelchair tennis. GPS units with a higher sampling rate should be advocated in further studies. Modifications to existing DL devices may be required to increase measurement precision. Further research into the validity of movement devices during match play will further inform the demands and movement patterns associated with wheelchair tennis. PMID:23820154

  10. Authorship Attribution in the E-mail Domain: A Study of the Effect of Size of Author Corpus and Topic on Accuracy of Identification

    DTIC Science & Technology

    2011-03-01

    Wilhelm Fucks discriminated between authors using the average number of syllables per word and average distance between equal-syllabled words. He concluded...363–390, 1939. [4] Conrad Mascol. Curves of pauline and pseudo-pauline style. Unitarian Review, 1888. [5] Wilhelm Fucks . On mathmatical analysis of

  11. Anatomy of the obturator region: relations to a trans-obturator sling.

    PubMed

    Whiteside, James L; Walters, Mark D

    2004-01-01

    Our objective was to determine the relationships between a trans-obturator sling and anatomic structures within the obturator region. The obturator regions of six cadavers were dissected and distances from the mid-point of the ischiopubic ramus to the muscles, nerves, and vessels of the region were measured. A trans-obturator sling was placed and distances from the device to the same anatomic structures were determined. Four additional cadavers were dissected to determine the device route of passage. The obturator canal is on average 4.4 cm from the midpoint of the ischiopubic rami. The trans-obturator sling passes on average 2.4 cm inferior-medial to the obturator canal. The anterior and posterior divisions of the obturator nerve are on average 3.4 and 2.8 cm, respectively, from a passed trans-obturator device. The device passed on average 1.1 cm from the most medial branch of the obturator vessels. Vascular and nerve structures are within 1-3 cm of the path of any device passed through the obturator foramen. A trans-obturator sling risks injury to these structures, although the small caliber of the vessels and the confined space in which they would bleed make the consequences of injury uncertain.

  12. Characteristics of On-road Diesel Vehicles: Black Carbon Emissions in Chinese Cities Based on Portable Emissions Measurement.

    PubMed

    Zheng, Xuan; Wu, Ye; Jiang, Jingkun; Zhang, Shaojun; Liu, Huan; Song, Shaojie; Li, Zhenhua; Fan, Xiaoxiao; Fu, Lixin; Hao, Jiming

    2015-11-17

    Black carbon (BC) emissions from heavy-duty diesel vehicles (HDDVs) are rarely continuously measured using portable emission measurement systems (PEMSs). In this study, we utilize a PEMS to obtain real-world BC emission profiles for 25 HDDVs in China. The average fuel-based BC emissions of HDDVs certified according to Euro II, III, IV, and V standards are 2224 ± 251, 612 ± 740, 453 ± 584, and 152 ± 3 mg kg(-1), respectively. Notably, HDDVs adopting mechanical pump engines had significantly higher BC emissions than those equipped with electronic injection engines. Applying the useful features of PEMSs, we can relate instantaneous BC emissions to driving conditions using an operating mode binning methodology, and the average emission rates for Euro II to Euro IV diesel trucks can be constructed. From a macroscopic perspective, we observe that average speed is a significant factor affecting BC emissions and is well correlated with distance-based emissions (R(2) = 0.71). Therefore, the average fuel-based and distance-based BC emissions on congested roads are 40 and 125% higher than those on freeways. These results should be taken into consideration in future emission inventory studies.

  13. Optimization methods of pulse-to-pulse alignment using femtosecond pulse laser based on temporal coherence function for practical distance measurement

    NASA Astrophysics Data System (ADS)

    Liu, Yang; Yang, Linghui; Guo, Yin; Lin, Jiarui; Cui, Pengfei; Zhu, Jigui

    2018-02-01

    An interferometer technique based on temporal coherence function of femtosecond pulses is demonstrated for practical distance measurement. Here, the pulse-to-pulse alignment is analyzed for large delay distance measurement. Firstly, a temporal coherence function model between two femtosecond pulses is developed in the time domain for the dispersive unbalanced Michelson interferometer. Then, according to this model, the fringes analysis and the envelope extraction process are discussed. Meanwhile, optimization methods of pulse-to-pulse alignment for practical long distance measurement are presented. The order of the curve fitting and the selection of points for envelope extraction are analyzed. Furthermore, an averaging method based on the symmetry of the coherence function is demonstrated. Finally, the performance of the proposed methods is evaluated in the absolute distance measurement of 20 μ m with path length difference of 9 m. The improvement of standard deviation in experimental results shows that these approaches have the potential for practical distance measurement.

  14. Gravitational acceleration as a cue for absolute size and distance?

    NASA Technical Reports Server (NTRS)

    Hecht, H.; Kaiser, M. K.; Banks, M. S.

    1996-01-01

    When an object's motion is influenced by gravity, as in the rise and fall of a thrown ball, the vertical component of acceleration is roughly constant at 9.8 m/sec2. In principle, an observer could use this information to estimate the absolute size and distance of the object (Saxberg, 1987a; Watson, Banks, von Hofsten, & Royden, 1992). In five experiments, we examined people's ability to utilize the size and distance information provided by gravitational acceleration. Observers viewed computer simulations of an object rising and falling on a trajectory aligned with the gravitational vector. The simulated objects were balls of different diameters presented across a wide range of simulated distances. Observers were asked to identify the ball that was presented and to estimate its distance. The results showed that observers were much more sensitive to average velocity than to the gravitational acceleration pattern. Likewise, verticality of the motion and visibility of the trajectory's apex had negligible effects on the accuracy of size and distance judgments.

  15. An Experimental Study of Small-Scale Variability of Raindrop Size Distribution

    NASA Technical Reports Server (NTRS)

    Tokay, Ali; Bashor, Paul G.

    2010-01-01

    An experimental study of small-scale variability of raindrop size distributions (DSDs) has been carried out at Wallops Island, Virginia. Three Joss-Waldvogel disdrometers were operated at a distance of 0.65, 1.05, and 1.70 km in a nearly straight line. The main purpose of the study was to examine the variability of DSDs and its integral parameters of liquid water content, rainfall, and reflectivity within a 2-km array: a typical size of Cartesian radar pixel. The composite DSD of rain events showed very good agreement among the disdrometers except where there were noticeable differences in midsize and large drops in a few events. For consideration of partial beam filling where the radar pixel was not completely covered by rain, a single disdrometer reported just over 10% more rainy minutes than the rainy minutes when all three disdrometers reported rainfall. Similarly two out of three disdrometers reported5%more rainy minutes than when all three were reporting rainfall. These percentages were based on a 1-min average, and were less for longer averaging periods. Considering only the minutes when all three disdrometers were reporting rainfall, just over one quarter of the observations showed an increase in the difference in rainfall with distance. This finding was based on a 15-min average and was even less for shorter averaging periods. The probability and cumulative distributions of a gamma-fitted DSD and integral rain parameters between the three disdrometers had a very good agreement and no major variability. This was mainly due to the high percentage of light stratiform rain and to the number of storms that traveled along the track of the disdrometers. At a fixed time step, however, both DSDs and integral rain parameters showed substantial variability. The standard deviation (SD) of rain rate was near 3 mm/h, while the SD of reflectivity exceeded 3 dBZ at the longest separation distance. These standard deviations were at 6-min average and were higher at shorter averaging periods. The correlations decreased with increasing separation distance. For rain rate, the correlations were higher than previous gauge-based studies. This was attributed to the differences in data processing and the difference in rainfall characteristics in different climate regions. It was also considered that the gauge sampling errors could be a factor. In this regard, gauge measurements were simulated employing existing disdrometer dataset. While a difference was noticed in cumulative distribution of rain occurrence between the simulated gauge and disdrometer observations, the correlations in simulated gauge measurements did not differ from the disdrometer measurements.

  16. Modeling a Mathematical to Quantify the Degree of Emergency Department Crowding

    NASA Astrophysics Data System (ADS)

    Chang, Y.; Pan, C.; Wen, J.

    2012-12-01

    The purpose of this study is to deduce a function from the admissions/discharge rate of patient flow to estimate a "Critical Point" that provides a reference for warning systems in regards to crowding in the emergency department (ED) of a hospital or medical clinic. In this study, a model of "Input-Throughput-Output" was used in our established mathematical function to evaluate the critical point. The function was defined as ∂ρ/∂t=-K×∂ρ/∂x , where ρ= number of patients per unit distance (also called density), t= time, x= distance, K= distance of patients movement per unit time. Using the average K of ED crowding, we could initiate the warning system at appropriate time and plan necessary emergency response to facilitate the patient process more smoothly. It was concluded that ED crowding can be quantified using the average value of K, and the value can be used as a reference for medical staff to give optimal emergency medical treatment to patients. Therefore, additional practical work should be launched to collect more precise quantitative data.

  17. Streaming motions and kinematic distances to molecular clouds

    NASA Astrophysics Data System (ADS)

    Ramón-Fox, F. G.; Bonnell, Ian A.

    2018-02-01

    We present high-resolution smoothed particle hydrodynamics simulations of a region of gas flowing in a spiral arm and identify dense gas clouds to investigate their kinematics with respect to a Milky Way model. We find that, on average, the gas in the arms can have a net radial streaming motion of vR ≈ -9 km s-1 and rotate ≈ 6 km s-1 slower than the circular velocity. This translates to average peculiar motions towards the Galaxy centre and opposite to Galactic rotation. These results may be sensitive to the assumed spiral arm perturbation, which is ≈ 3 per cent of the disc potential in our model. We compare the actual distance and the kinematic estimate and we find that streaming motions introduce systematic offsets of ≈1 kpc. We find that the distance error can be as large as ±2 kpc, and the recovered cloud positions have distributions that can extend significantly into the inter-arm regions. We conclude that this poses a difficulty in tracing spiral arm structure in molecular cloud surveys.

  18. No clustering for linkage map based on low-copy and undermethylated microsatellites.

    PubMed

    Zhou, Yi; Gwaze, David P; Reyes-Valdés, M Humberto; Bui, Thomas; Williams, Claire G

    2003-10-01

    Clustering has been reported for conifer genetic maps based on hypomethylated or low-copy molecular markers, resulting in uneven marker distribution. To test this, a framework genetic map was constructed from three types of microsatellites: low-copy, undermethylated, and genomic. These Pinus taeda L. microsatellites were mapped using a three-generation pedigree with 118 progeny. The microsatellites were highly informative; of the 32 markers in intercross configuration, 29 were segregating for three or four alleles in the progeny. The sex-averaged map placed 51 of the 95 markers in 15 linkage groups at LOD > 4.0. No clustering or uneven distribution across the genome was observed. The three types of P. taeda microsatellites were randomly dispersed within each linkage group. The 51 microsatellites covered a map distance of 795 cM, an average distance of 21.8 cM between markers, roughly half of the estimated total map length. The minimum and maximum distances between any two bins was 4.4 and 45.3 cM, respectively. These microsatellites provided anchor points for framework mapping for polymorphism in P. taeda and other closely related hard pines.

  19. Forest cover influences dispersal distance of white-tailed deer

    USGS Publications Warehouse

    Long, E.S.; Diefenbach, D.R.; Rosenberry, C.S.; Wallingford, B.D.; Grund, M.D.

    2005-01-01

    Animal dispersal patterns influence gene flow, disease spread, population dynamics, spread of invasive species, and establishment of rare or endangered species. Although differences in dispersal distances among taxa have been reported, few studies have described plasticity of dispersal distance among populations of a single species. In 2002-2003, we radiomarked 308 juvenile (7- to 10-month-old), male white-tailed deer (Odocoileus virginianus) in 2 study areas in Pennsylvania. By using a meta-analysis approach, we compared dispersal rates and distances from these populations together with published reports of 10 other nonmigratory populations of white-tailed deer. Population density did not influence dispersal rate or dispersal distance, nor did forest cover influence dispersal rate. However, average (r2 = 0.94, P < 0.001, d.f. = 9) and maximum (r2 = 0.86, P = 0.001, d.f. = 7) dispersal distances of juvenile male deer were greater in habitats with less forest cover. Hence, dispersal behavior of this habitat generalist varies, and use of landscape data to predict population-specific dispersal distances may aid efforts to model population spread, gene flow, or disease transmission. ?? 2005 American Society of Mammalogists.

  20. A novel high-speed PLC communication modem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abraham, K.C.; Roy, S.

    1992-10-01

    In this paper an innovative design for power line carrier (PLC) communication using digitally modulated signals is presented. The major contribution consists of a new signal coupler to the power line that achieves a stable transmission bandwidth of 4 KHz on distribution lines over long distances. Preliminary field tests achieved half-duplex operation at 1.2 Kbaud over a distribution power line to the 120V network and back with a symbol error rate of about 2% using less than about 10 W of average transmitted power, which is considerably superior to the present state-of-the-art PLC modems. Full-duplex operation over 120/240V intra-building wiringmore » has also been field tested at 9.6 Kbaud over distances of 3000 ft. using 1W of average transmitted power.« less

  1. Effect of limb rotation on radiographic alignment in total knee arthroplasties.

    PubMed

    Radtke, Kerstin; Becher, Christoph; Noll, Yvonne; Ostermeier, Sven

    2010-04-01

    Even in a well-aligned total knee arthroplasty (TKA), limb rotation at the time of radiographic assessment will alter the measurement of alignment. This could influence the radiographic outcome of TKA. The purpose of this study was to evaluate the effect of limb rotation on radiographic alignment after TKA and to establish a re-calculation of this rotation by using existing radiographic landmarks. Synthetic femur and tibia (Sawbones), Inc. Vashon Island, WA) were used to create a TKA of the Triathlon knee prosthesis system (Stryker), Limerick, Ireland). The femoral alignment was 6.5 degrees valgus. The model was fixed in an upright stand. Five series of nine anteroposterior (AP) long leg radiographs were taken on a 30 cm x 120 cm plates in full extension with the limb rotated, in 5 degrees increments, from 20 degrees external rotation to 20 degrees internal rotation. After digitizing each radiograph (Scanner Hewlett Packard XJ 527), an observer measured the anatomic mechanical angle of the femur [AMA ( degrees )], the mechanical lateral proximal femur angle [mLPFA ( degrees )], the mechanical lateral distal femur angle [mLDFA ( degrees )], the mechanical medial proximal tibia angle [mMPTA ( degrees )] and the mechanical lateral distal tibia angle [mLDTA ( degrees )] using a digital measurement software (MediCAD, Hectec, Altfraunhofen, Germany). Besides, the observer measured the geometrical distances of the femoral component figured on the long leg radiograph. A ratio of one distance to another was measured (called femoral component distance ratio). The average radiographic anatomic alignment ranged from 6.827 degrees AMA (SD = 0.22 degrees ) in 20 degrees internal rotation to 4.627 degrees AMA (SD = 0.22 degrees ) in 20 degrees external rotation. Average mLPFA ( degrees ) ranged from 101.63 degrees (SD = 0.63) in 20 degrees internal rotation to 93.60 degrees (SD = 0.74 degrees ) in 20 degrees external rotation. Average mLDFA ( degrees ) ranged from 90.59 degrees (SD = 3.01 degrees ) in 20 degrees internal rotation to 86.76 degrees (SD = 0.36 degrees ) in 20 degrees external rotation. Average mMPTA ( degrees ) ranged from 90.35 degrees (SD = 0.81 degrees ) in 20 degrees internal rotation to 88.49 degrees (SD = 0.52 degrees ) in 20 degrees external rotation. Average mLDTA ( degrees ) ranged from 98.89 degrees (SD = 2.3 degrees ) in 20 degrees internal rotation to 90.53 degrees (SD = 3.39 degrees ) in 20 degrees external rotation. Without an application of limb rotation, the femoral component distance ratio was measured to be 0.89 (SD = 0.01), in 20 degrees internal rotation 0.63 (SD = 0.01) and in 20 degrees external rotation 1.16 (SD = 0.01). Limb rotation had a highly statistically significant effect on measured anatomic alignment and mechanical angles. A correlation between limb rotation, anatomic mechanical angle, mechanical angles measured at femur and tibia and the femoral component distance ratio was established. As the anatomic mechanical angle and the femoral component distance ratio change linearly in the range of 20 degrees internal and external limb rotation, a calculation of the femoral component distance ratio could be used to re-calculate the limb rotation at the time of radiographic assessment to evaluate the evidence of a long leg radiograph.

  2. Effect of high-speed running on hamstring strain injury risk.

    PubMed

    Duhig, Steven; Shield, Anthony J; Opar, David; Gabbett, Tim J; Ferguson, Cameron; Williams, Morgan

    2016-12-01

    Hamstring strain injuries (HSIs) are common within the Australian Football League (AFL) with most occurring during high-speed running (HSR). Therefore, this study investigated possible relationships between mean session running distances, session ratings of perceived exertion (s-RPE) and HSIs within AFL footballers. Global positioning system (GPS)-derived running distances and s-RPE for all matches and training sessions over two AFL seasons were obtained from one AFL team. All HSIs were documented and each player's running distances and s-RPE were standardised to their 2-yearly session average, then compared between injured and uninjured players in the 4 weeks (weeks -1, -2, -3 and -4) preceding each injury. Higher than 'typical' (ie, z=0) HSR session means were associated with a greater likelihood of HSI (week -1: OR=6.44, 95% CI=2.99 to 14.41, p<0.001; summed weeks -1 and -2: OR=3.06, 95% CI=2.03 to 4.75, p<0.001; summed weeks -1, -2 and -3: OR=2.22, 95% CI=1.66 to 3.04, p<0.001; and summed weeks -1, -2, -3 and -4: OR=1.96, 95% CI=1.54 to 2.51, p<0.001). However, trivial differences were observed between injured and uninjured groups for standardised s-RPE, total distance travelled and distances covered whilst accelerating and decelerating. Increasing AFL experience was associated with a decreased HSI risk (OR=0.77, 95% CI 0.57 to 0.97, p=0.02). Furthermore, HSR data modelling indicated that reducing mean distances in week -1 may decrease the probability of HSI. Exposing players to large and rapid increases in HSR distances above their 2-yearly session average increased the odds of HSI. However, reducing HSR in week -1 may offset HSI risk. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  3. Molecular dynamics studies of a DNA-binding protein: 2. An evaluation of implicit and explicit solvent models for the molecular dynamics simulation of the Escherichia coli trp repressor.

    PubMed Central

    Guenot, J.; Kollman, P. A.

    1992-01-01

    Although aqueous simulations with periodic boundary conditions more accurately describe protein dynamics than in vacuo simulations, these are computationally intensive for most proteins. Trp repressor dynamic simulations with a small water shell surrounding the starting model yield protein trajectories that are markedly improved over gas phase, yet computationally efficient. Explicit water in molecular dynamics simulations maintains surface exposure of protein hydrophilic atoms and burial of hydrophobic atoms by opposing the otherwise asymmetric protein-protein forces. This properly orients protein surface side chains, reduces protein fluctuations, and lowers the overall root mean square deviation from the crystal structure. For simulations with crystallographic waters only, a linear or sigmoidal distance-dependent dielectric yields a much better trajectory than does a constant dielectric model. As more water is added to the starting model, the differences between using distance-dependent and constant dielectric models becomes smaller, although the linear distance-dependent dielectric yields an average structure closer to the crystal structure than does a constant dielectric model. Multiplicative constants greater than one, for the linear distance-dependent dielectric simulations, produced trajectories that are progressively worse in describing trp repressor dynamics. Simulations of bovine pancreatic trypsin were used to ensure that the trp repressor results were not protein dependent and to explore the effect of the nonbonded cutoff on the distance-dependent and constant dielectric simulation models. The nonbonded cutoff markedly affected the constant but not distance-dependent dielectric bovine pancreatic trypsin inhibitor simulations. As with trp repressor, the distance-dependent dielectric model with a shell of water surrounding the protein produced a trajectory in better agreement with the crystal structure than a constant dielectric model, and the physical properties of the trajectory average structure, both with and without a nonbonded cutoff, were comparable. PMID:1304396

  4. Kinematic Analysis of Javelin Throw Performed by Wheelchair Athletes of Different Functional Classes

    PubMed Central

    Chow, John W.; Kuenster, Ann F.; Lim, Young-tae

    2003-01-01

    The purpose of this study was to identify those kinematic characteristics that are most closely related to the functional classification of a wheelchair athlete and measured distance of a javelin throw. Two S-VHS camcorders (60 field·s-1) were used to record the performance of 15 males of different classes. Each subject performed 6-10 throws and the best two legal throws from each subject were selected for analysis. Three-dimensional kinematics of the javelin and upper body segments at the instant of release and during the throw (delivery) were determined. The selection of kinematic parameters that were analyzed in this study was based on a javelin throw model showing the factors that determine the measured distance of a throw. The average of two throws for each subject was used to compute Spearman rank correlation coefficients between selected parameters and measured distance, and between selected parameters and the functional classification. The speeds and angles of the javelin at release, ranged from 9.1 to 14.7 m·s-1 and 29.6 to 35.8°, respectively, were smaller than those exhibited by elite male able-bodied throwers. As expected, the speed of the javelin at release was significantly correlated to both the classification (p<0.01) and measured distance (p<0.001). Of the segmental kinematic parameters, significant correlations were found between the trunk inclination at release and classification and between the angular speed at release and measured distance (p<0.01 for both). The angular speed of the shoulder girdle at release and the average angular speeds of the shoulder girdle during the delivery were significantly correlated to both the classification and measured distance (p<0.05). The results indicate that shoulder girdle movement during the delivery is an important determinant of classification and measured distance. PMID:24616609

  5. Calculated dipole moment and energy in collision of a hydrogen molecule and a hydrogen atom

    NASA Technical Reports Server (NTRS)

    Patch, R. W.

    1973-01-01

    Calculations were carried out using three Slater-type 1s orbitals in the orthogonalized valencebond theory of McWeeny. Each orbital exponent was optimized, the H2 internuclear distance was varied from 7.416 x 10 to the -11th power to 7.673 x 10 to the -11th power m (1.401 to 1.450 bohrs). The intermolecular distance was varied from 1 to 4 bohrs (0.5292 to 2.117 x 10 to the 10th power). Linear, scalene, and isosceles configurations were used. A weighted average of the interaction energies was taken for each intermolecular distance. Although energies are tabulated, the principal purpose was to calculate the electric dipole moment and its derivative with respect to H2 internuclear distance.

  6. Dependence of average inter-particle distance upon the temperature of neutrals in dusty plasma crystals

    NASA Astrophysics Data System (ADS)

    Nikolaev, V. S.; Timofeev, A. V.

    2018-01-01

    It is often suggested that inter-particle distance in stable dusty plasma structures decreases with cooling as a square root of neutral gas temperature. Deviations from this dependence (up to the increase at cryogenic temperatures) found in the experimental results for the pressures range 0.1-8.0 mbar and for the currents range 0.1-1.0 mA are given. Inter-particle distance dependences on the charge of particles, parameter of the trap and the screening length in surrounding plasma are obtained for different conditions from molecular dynamics simulations. They are well approximated by power functions in the mentioned range of parameters. It is found that under certain assumptions thermophoretical force is responsible for inter-particle distance increase at cryogenic temperatures.

  7. Differences in kata performance time and distance from a marker for experienced Shotokan karateka under normal sighted and blindfolded conditions.

    PubMed

    Layton, Clive; Avenell, Leon

    2002-08-01

    10 experienced Shotokan karateka were tested on performance time and distance from a marker on the five Heian kata under normal sighted and blind-folded conditions. Whilst each kata's line of movement is different, it is the intention to start and finish at the same location. Analysis showed that despite an average of 16.8 yr. of training, whilst timing was not significantly affected on four of the kata by subjects being deprived of the visual sense, the group's mean change in distance from an original marker was significant for performances on three of the kata.

  8. Real-world emissions and fuel consumption of diesel buses and trucks in Macao: From on-road measurement to policy implications

    NASA Astrophysics Data System (ADS)

    Wu, Xiaomeng; Zhang, Shaojun; Wu, Ye; Li, Zhenhua; Zhou, Yu; Fu, Lixin; Hao, Jiming

    2015-11-01

    A total of 13 diesel buses and 12 diesel trucks in Macao were tested using portable emission measurement systems (PEMS) including a SEMTECH-DS for gaseous emissions and a SEMTECH-PPMD for PM2.5. The average emission rates of gaseous pollutants and CO2 are developed with the operating mode defined by the instantaneous vehicle specific power (VSP) and vehicle speed. Both distance-based and fuel mass-based emission factors for gaseous pollutants (e.g., CO, THC and NOX) are further estimated under typical driving conditions. The average distance-based NOX emission of heavy-duty buses (HDBs) is higher than 13 g km-1. Considering the unfavorable conditions for selective reductions catalyst (SCR) systems, such as low-speed driving conditions, more effective technology options (e.g., dedicated natural gas buses and electric buses) should be considered by policy makers in Macao. We identified strong effects of the vehicle size, engine displacement and driving conditions on real-world CO2 emission factors and fuel consumption for diesel vehicles. Therefore, detailed profiles regarding vehicle specifications can reduce the uncertainty in their fleet-average on-road fuel consumption. In addition, strong correlations between relative emission factors and driving conditions indicated by the average speed of generated micro-trips are identified based on a micro-trip method. For example, distance-based emission factors of HDBs will increase by 39% for CO, 29% for THC, 43% for NOX and 26% for CO2 when the average speed decreases from 30 km h-1 to 20 km h-1. The mitigation of on-road emissions from diesel buses and trucks by improving traffic conditions through effective traffic and economic management measures is therefore required. This study demonstrates the important role of PEMS in understanding vehicle emissions and mitigation strategies from science to policy perspectives.

  9. SU-E-I-48: Comparison of CTDIw and Averaged CTDI Over X-Y Plane.

    PubMed

    Liang, Y; Emerson, S; Schultz, C

    2012-06-01

    The goal of this study is to investigate the accuracy of using CTDIw to estimate the averaged CTDI over x-y plane. We used a Siemens Sensation 16 slice scanner, a nested 3 piece CTDI phantom with diameters of 10, 16, and 32 cm for each piece, a CT pencil ion chamber, and aluminum oxide OSL dosimeters. In axial mode, we measured the exposure with ion chamber at the 3, 6, 9, and 12 o'clock positions at distances of 4, 7, and 15 cm from the center of a 32 cm CTDI phantom, as well as at the center of the phantom. Measurements were performed at 80, 100, 120, and 140 kVp on the adult abdomen, adult head, and pediatric body phantom, using only the distances of 0, 4, and 7 cm from the phantom center for the smaller 16 cm diameter phantom. We did similar measurements using nanoDot dosimeters and the 32 cm phantom at 120 kVp in helical mode using a pitch of 0.8, 1.0, and 1.2. The data obtained at four different outer clock positions was averaged and three models (linear, quadratic, and exponential) were used to fit exposure as a function of distance to the phantom center. We calculated the average CTDI over the x- y plane mathematically using the above models and compared the results with traditional CTDIw. In axial mode, the difference is within 6% for 32 cm phantom, with a slight increase in variance at low kVp, while the difference is within 1% for the 16 cm phantom. In helical mode with OSLs, the difference is within 2.5% for pitch 0.8-1.2. The current CTDIw provides an accurate estimate of the averaged CTDI over the x-y plane for both axial and helical modes. © 2012 American Association of Physicists in Medicine.

  10. Properties of star clusters - I. Automatic distance and extinction estimates

    NASA Astrophysics Data System (ADS)

    Buckner, Anne S. M.; Froebrich, Dirk

    2013-12-01

    Determining star cluster distances is essential to analyse their properties and distribution in the Galaxy. In particular, it is desirable to have a reliable, purely photometric distance estimation method for large samples of newly discovered cluster candidates e.g. from the Two Micron All Sky Survey, the UK Infrared Deep Sky Survey Galactic Plane Survey and VVV. Here, we establish an automatic method to estimate distances and reddening from near-infrared photometry alone, without the use of isochrone fitting. We employ a decontamination procedure of JHK photometry to determine the density of stars foreground to clusters and a galactic model to estimate distances. We then calibrate the method using clusters with known properties. This allows us to establish distance estimates with better than 40 per cent accuracy. We apply our method to determine the extinction and distance values to 378 known open clusters and 397 cluster candidates from the list of Froebrich, Scholz & Raftery. We find that the sample is biased towards clusters of a distance of approximately 3 kpc, with typical distances between 2 and 6 kpc. Using the cluster distances and extinction values, we investigate how the average extinction per kiloparsec distance changes as a function of the Galactic longitude. We find a systematic dependence that can be approximated by AH(l) [mag kpc-1] = 0.10 + 0.001 × |l - 180°|/° for regions more than 60° from the Galactic Centre.

  11. A simulation trainer for complex articular fracture surgery.

    PubMed

    Yehyawi, Tameem M; Thomas, Thaddeus P; Ohrt, Gary T; Marsh, J Lawrence; Karam, Matthew D; Brown, Thomas D; Anderson, Donald D

    2013-07-03

    The purposes of this study were (1) to develop a physical model to improve articular fracture reduction skills, (2) to develop objective assessment methods to evaluate these skills, and (3) to assess the construct validity of the simulation. A surgical simulation was staged utilizing surrogate tibial plafond fractures. Multiple three-segment radio-opacified polyurethane foam fracture models were produced from the same mold, ensuring uniform surgical complexity between trials. Using fluoroscopic guidance, five senior and seven junior orthopaedic residents reduced the fracture through a limited anterior window. The residents were assessed on the basis of time to completion, hand movements (tracked with use of a motion capture system), and quality of the obtained reduction. All but three of the residents successfully reduced and fixed the fracture fragments (one senior resident and two junior residents completed the reduction but were unsuccessful in fixating all fragments). Senior residents had an average time to completion of 13.43 minutes, an average gross articular step-off of 3.00 mm, discrete hand motions of 540 actions, and a cumulative hand motion distance of 79 m. Junior residents had an average time to completion of 14.75 minutes, an average gross articular step-off of 3.09 mm, discrete hand motions of 511 actions, and a cumulative hand motion distance of 390 m. The large difference in cumulative hand motion distance, despite comparable numbers of discrete hand motion events, indicates that senior residents were more precise in their hand motions. The present experiment establishes the basic construct validity of the simulation trainer. Further studies are required to demonstrate that this laboratory-based model for articular fracture reduction training, along with an objective assessment of performance, can be used to improve resident surgical skills.

  12. Genetic mapping of 15 human X chromosomal forensic short tandem repeat (STR) loci by means of multi-core parallelization.

    PubMed

    Diegoli, Toni Marie; Rohde, Heinrich; Borowski, Stefan; Krawczak, Michael; Coble, Michael D; Nothnagel, Michael

    2016-11-01

    Typing of X chromosomal short tandem repeat (X STR) markers has become a standard element of human forensic genetic analysis. Joint consideration of many X STR markers at a time increases their discriminatory power but, owing to physical linkage, requires inter-marker recombination rates to be accurately known. We estimated the recombination rates between 15 well established X STR markers using genotype data from 158 families (1041 individuals) and following a previously proposed likelihood-based approach that allows for single-step mutations. To meet the computational requirements of this family-based type of analysis, we modified a previous implementation so as to allow multi-core parallelization on a high-performance computing system. While we obtained recombination rate estimates larger than zero for all but one pair of adjacent markers within the four previously proposed linkage groups, none of the three X STR pairs defining the junctions of these groups yielded a recombination rate estimate of 0.50. Corroborating previous studies, our results therefore argue against a simple model of independent X chromosomal linkage groups. Moreover, the refined recombination fraction estimates obtained in our study will facilitate the appropriate joint consideration of all 15 investigated markers in forensic analysis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. Mapping the Rust Resistant Loci MXC3 and MER in P. trichocarpa and Assessing the Intermarker Linkage Disequilibrium in MXC3 Region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yin, Tongming; Difazio, Stephen P.; Gunter, Lee E

    In an attempt to elucidate the molecular mechanisms of Melampsora rust resistance in Populus trichocarpa, we have mapped two resistance loci, MXC3 and MER, and intensively characterized the flanking genomic sequence for the MXC3 locus and the level of linkage disequilibrium (LD) in natural populations. We used an interspecific backcross pedigree and a genetic map that was highly saturated with AFLP and SSR markers, and assembled shotgun-sequence data in the region containing markers linked to MXC3. The two loci were mapped to different linkage groups. Linkage disequilibrium for MXC3 was confined to two closely linked regions spanning 34 and 16more » kb, respectively. The MXC3 region also contained six disease-resistance candidate genes. The MER and MXC3 loci are clearly distinct, and may have different mechanisms of resistance, as different classes of putative resistance genes were present near each locus. The suppressed recombination previously observed in the MXC3 region was possibly caused by extensive hemizygous rearrangements confined to the original parent tree. The relatively low observed LD may facilitate association studies using candidate genes for rust resistance, but will probably inhibit marker-aided selection.« less

  14. Cost of thinning 50-year-old Douglas-fir for pulpwood at Voight Creek Experimental Forest.

    Treesearch

    Norman P. Worthington

    1961-01-01

    Analyses of time and cost data gathered on the Voight Creek Experimental Forest from six thinnings in a 50-year-old stand of Douglas-fir showed that average skidding distance and diameter of average tree cut were the chief factors affecting the production time in thinning these pulpwood stands. Cut per acre had negligible influence. Contractors' production...

  15. Center-to-Limb Variation of Deprojection Errors in SDO/HMI Vector Magnetograms

    NASA Astrophysics Data System (ADS)

    Falconer, David; Moore, Ronald; Barghouty, Nasser; Tiwari, Sanjiv K.; Khazanov, Igor

    2015-04-01

    For use in investigating the magnetic causes of coronal heating in active regions and for use in forecasting an active region’s productivity of major CME/flare eruptions, we have evaluated various sunspot-active-region magnetic measures (e.g., total magnetic flux, free-magnetic-energy proxies, magnetic twist measures) from HMI Active Region Patches (HARPs) after the HARP has been deprojected to disk center. From a few tens of thousand HARP vector magnetograms (of a few hundred sunspot active regions) that have been deprojected to disk center, we have determined that the errors in the whole-HARP magnetic measures from deprojection are negligibly small for HARPS deprojected from distances out to 45 heliocentric degrees. For some purposes the errors from deprojection are tolerable out to 60 degrees. We obtained this result by the following process. For each whole-HARP magnetic measure: 1) for each HARP disk passage, normalize the measured values by the measured value for that HARP at central meridian; 2) then for each 0.05 Rs annulus, average the values from all the HARPs in the annulus. This results in an average normalized value as a function of radius for each measure. Assuming no deprojection errors and that, among a large set of HARPs, the measure is as likely to decrease as to increase with HARP distance from disk center, the average of each annulus is expected to be unity, and, for a statistically large sample, the amount of deviation of the average from unity estimates the error from deprojection effects. The deprojection errors arise from 1) errors in the transverse field being deprojected into the vertical field for HARPs observed at large distances from disk center, 2) increasingly larger foreshortening at larger distances from disk center, and 3) possible errors in transverse-field-direction ambiguity resolution.From the compiled set of measured vales of whole-HARP magnetic nonpotentiality parameters measured from deprojected HARPs, we have examined the relation between each nonpotentiality parameter and the speed of CMEs from the measured active regions. For several different nonpotentiality parameters we find there is an upper limit to the CME speed, the limit increasing as the value of the parameter increases.

  16. Discrimination against Obese Exercise Clients: An Experimental Study of Personal Trainers.

    PubMed

    Fontana, Fabio; Bopes, Jonathan; Bendixen, Seth; Speed, Tyler; George, Megan; Mack, Mick

    2018-01-01

    The aim of the study was to compare exercise recommendations, attitudes, and behaviors of personal trainers toward clients of different weight statuses. Fifty-two personal trainers participated in the study. The data collection was organized into two phases. In phase one, trainers read a profile and watched the video displaying an interview of either an obese or an average-weight client. Profiles and video interviews were identical except for weight status. Then, trainers provided exercise recommendations and rated their attitude toward the client. In phase two, trainers personally met an obese or an average-weight mock client. Measures were duration and number of advices provided by the trainer to a question posed by the client and sitting distance between trainer and client. There were no significant differences in exercise intensity ( p = .94), duration of first session ( p = .65), and total exercise duration of first week ( p = .76) prescribed to the obese and average-weight clients. The attitude of the personal trainers toward the obese client were not significantly different from the attitude of personal trainers toward the average-weight client ( p = .58). The number of advices provided ( p = .49), the duration of the answer ( p = .55), and the distance personal trainers sat from the obese client ( p = .68) were not significantly different from the behaviors displayed toward the average-weight client. Personal trainers did not discriminate against obese clients in professional settings.

  17. Investigating the Effect of IMF Path Length on Pitch-angle Scattering of Strahl within 1 au

    NASA Astrophysics Data System (ADS)

    Graham, G. A.; Rae, I. J.; Owen, C. J.; Walsh, A. P.

    2018-03-01

    Strahl is the strongly field-aligned, beam-like population of electrons in the solar wind. Strahl width is observed to increase with distance from the Sun, and hence strahl electrons must be subject to in-transit scattering effects. Different energy relations have been both observed and modeled for both strahl width and the width increase with radial distance. Thus, there is much debate regarding what mechanism(s) scatter strahl. In this study, we use a novel method to investigate strahl evolution within 1 au by estimating the distance traveled by the strahl along the interplanetary magnetic field (IMF). We do this by implementing methods developed in previous studies, which make use of the onset of solar energetic particles at ∼1 au. Thus, we are able to obtain average strahl broadening in relation to electron energy and distance, while also taking into account the general effect of IMF topology and adiabatic focusing experienced by strahl. We find that average strahl width broadens with distance traveled along the IMF, which suggests that strahl width is related to the path length taken by the strahl from the Sun to 1 au. We also find that strahl pitch-angle width broadening per au along the IMF length increased with strahl energy, which suggests that the dominant strahl pitch-angle scattering mechanism likely has an inherent energy relation. Our pitch-angle broadening results provide a testable energy relation for the upcoming Parker Solar Probe and Solar Orbiter missions, which are both set to provide unprecedented new observations within 1 au.

  18. Dispersal, habitat differences, and comparative phylogeography of Southeast Asian seahorses (Syngnathidae: Hippocampus).

    PubMed

    Lourie, S A; Green, D M; Vincent, A C J

    2005-04-01

    Four distinct phylogeographical patterns across Southeast Asia were observed for four species of seahorse (genus Hippocampus) with differing ecologies. For all species, genetic differentiation (based on cytochrome b sequence comparisons) was significantly associated with sample site (Phi(ST) = 0.190-0.810, P < 0.0001) and with geographical distance (Mantel's r = 0.37-0.59, P < 0.019). Geographic locations of genetic breaks were inconsistent across species in 7/10 comparisons, although some similarities across species were also observed. The two shallow-water species (Hippocampus barbouri and Hippocampus kuda) have colonized the Sunda Shelf to a lesser degree than the two deeper-water species (Hippocampus spinosissimus and Hippocampus trimaculatus). In all species the presence of geographically restricted haplotypes in the Philippines could indicate past population fragmentation and/or long-distance colonization. A nested clade analysis (NCA) revealed that long-distance colonization and/or fragmentation were likely the dominant forces that structure populations of the two shallow-water species, whereas range expansion and restricted dispersal with isolation by distance were proportionally more important in the history of the two deeper-water species. H. trimaculatus has the most widespread haplotypes [average clade distance (D(c)) of nonsingleton haplotypes = 1169 km], indicating potentially high dispersal capabilities, whereas H. barbouri has the least widespread haplotypes (average D(c) = 67 km) indicating potentially lower dispersal capabilities. Pleistocene separation of marine basins and postglacial flooding of the Sunda Shelf are extrinsic factors likely to have contributed to the phylogeographical structure observed, whereas differences among the species appear to reflect their individual ecologies.

  19. Beyond Neighborhood Food Environments: Distance Traveled to Food Establishments in 5 US Cities, 2009–2011

    PubMed Central

    Han, Bing; Cohen, Deborah A.

    2015-01-01

    Introduction Accurate conceptualizations of neighborhood environments are important in the design of policies and programs aiming to improve access to healthy food. Neighborhood environments are often defined by administrative units or buffers around points of interest. An individual may eat and shop for food within or outside these areas, which may not reflect accessibility of food establishments. This article examines the relevance of different definitions of food environments. Methods We collected data on trips to food establishments using a 1-week food and travel diary and global positioning system devices. Spatial-temporal clustering methods were applied to identify homes and food establishments visited by study participants. Results We identified 513 visits to food establishments (sit-down restaurants, fast-food/convenience stores, malls or stores, groceries/supermarkets) by 135 participants in 5 US cities. The average distance between the food establishments and homes was 2.6 miles (standard deviation, 3.7 miles). Only 34% of the visited food establishments were within participants’ neighborhood census tract. Buffers of 1 or 2 miles around the home covered 55% to 65% of visited food establishments. There was a significant difference in the mean distances to food establishments types (P = .008). On average, participants traveled the longest distances to restaurants and the shortest distances to groceries/supermarkets. Conclusion Many definitions of the neighborhood food environment are misaligned with individual travel patterns, which may help explain the mixed findings in studies of neighborhood food environments. Neighborhood environments defined by actual travel activity may provide more insight on how the food environment influences dietary and food shopping choices. PMID:26247426

  20. STAR FORMATION IN DWARF GALAXIES OF THE NEARBY CENTAURUS A GROUP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cote, Stephanie; Draginda, Adam; Skillman, Evan D.

    2009-10-15

    We present H{alpha} narrow-band imaging of 17 dwarf irregular (dI) galaxies in the nearby Centaurus A Group. Although all large galaxies of the group are or recently have been through a period of enhanced star formation, the dIs have normal star formation rates (SFRs) and do not contain a larger fraction of dwarf starbursts than other nearby groups such as the Sculptor Group or the Local Group. Most of the galaxies in the group now have fairly accurately known distances, which enables us to obtain relative distances between dIs and larger galaxies of the group. We find that the dImore » SFRs do not depend on local environment, and in particular they do not show any correlation with the distance of the dI to the nearest large galaxy of the group. There is a clear morphology-density relation in the Centaurus A Group, similar to the Sculptor Group and Local Group, in the sense that dwarf ellipticals (dEs)/dwarf spheroidals (dSphs) tend to be at small distances from the more massive galaxies of the group, while dIs are on average at larger distances. We find four transition dwarfs in the Group, dwarfs that show characteristics of both dE/dSphs and dIs, and which contain cold gas but no current star formation. Interestingly, the transition dwarfs have an average distance to the more massive galaxies, which is intermediate between those of the dEs/dSphs and dIs and which is quite large: 0.54 {+-} 0.31 Mpc. This large distance poses some difficulty for the most popular scenarios proposed for transforming a dI into a dE/dSph (ram-pressure with tidal stripping or galaxy harassment). If the observed transition dwarfs are indeed missing links between dIs and dE/dSphs, their relative isolation makes it less likely to have been produced by these mechanisms. An inhomogeneous intergalactic medium containing higher density clumps would be able to ram-pressure strip the dIs at larger distances from the more massive galaxies of the group.« less

  1. Foveal Curvature and Asymmetry Assessed Using Optical Coherence Tomography.

    PubMed

    VanNasdale, Dean A; Eilerman, Amanda; Zimmerman, Aaron; Lai, Nicky; Ramsey, Keith; Sinnott, Loraine T

    2017-06-01

    The aims of this study were to use cross-sectional optical coherence tomography imaging and custom curve fitting software to evaluate and model the foveal curvature as a spherical surface and to compare the radius of curvature in the horizontal and vertical meridians and test the sensitivity of this technique to anticipated meridional differences. Six 30-degree foveal-centered radial optical coherence tomography cross-section scans were acquired in the right eye of 20 clinically normal subjects. Cross sections were manually segmented, and custom curve fitting software was used to determine foveal pit radius of curvature using the central 500, 1000, and 1500 μm of the foveal contour. Radius of curvature was compared across different fitting distances. Root mean square error was used to determine goodness of fit. The radius of curvature was compared between the horizontal and vertical meridians for each fitting distance. There radius of curvature was significantly different when comparing each of the three fitting distances (P < .01 for each comparison). The average radii of curvature were 970 μm (95% confidence interval [CI], 913 to 1028 μm), 1386 μm (95% CI, 1339 to 1439 μm), and 2121 μm (95% CI, 2066 to 2183) for the 500-, 1000-, and 1500-μm fitting distances, respectively. Root mean square error was also significantly different when comparing each fitting distance (P < .01 for each comparison). The average root mean square errors were 2.48 μm (95% CI, 2.41 to 2.53 μm), 6.22 μm (95% CI, 5.77 to 6.60 μm), and 13.82 μm (95% CI, 12.93 to 14.58 μm) for the 500-, 1000-, and 1500-μm fitting distances, respectively. The radius of curvature between the horizontal and vertical meridian radii was statistically different only in the 1000- and 1500-μm fitting distances (P < .01 for each), with the horizontal meridian being flatter than the vertical. The foveal contour can be modeled as a sphere with low curve fitting error over a limited distance and capable of detecting subtle foveal contour differences between meridians.

  2. A comparison of the relative biological effectiveness of low energy electronic brachytherapy sources in breast tissue: a Monte Carlo study.

    PubMed

    White, Shane A; Reniers, Brigitte; de Jong, Evelyn E C; Rusch, Thomas; Verhaegen, Frank

    2016-01-07

    Electronic brachytherapy sources use low energy photons to treat the tumor bed during or after breast-conserving surgery. The relative biological effectiveness of two electronic brachytherapy sources was explored to determine if spectral differences due to source design influenced radiation quality and if radiation quality decreased with distance in the breast. The RBE was calculated through the number of DNA double strand breaks (RBEDSB) using the Monte Carlo damage simulator (MCDS) in combination with other Monte Carlo electron/photon spectrum calculations. 50kVp photons from the Intrabeam (Carl Zeiss Surgical) and Axxent (Xoft) through 40-mm spherical applicators were simulated to account for applicator and tissue attenuation in a variety of breast tissue compositions. 40kVp Axxent photons were also simulated. Secondary electrons (known to be responsible for most DNA damage) spectra at different distance were inputted into MCDS to calculate the RBEDSB. All RBEDSB used a cobalt-60 reference. RBEDSB data was combined with corresponding average photon spectrum energy for the Axxent and applied to model-based average photon energy distributions to produce an RBEDSB map of an accelerated partial breast irradiation (APBI) patient. Both Axxent and Intrabeam 50kVp spectra were shown to have a comparable RBEDSB of between 1.4 and 1.6 at all distances in spite of progressive beam hardening. The Axxent 40kVp also demonstrated a similar RBEDSB at distances. Most RBEDSB variability was dependent on the tissue type as was seen in rib (RBEDSB  ≈  1.4), gland (≈1.55), adipose (≈1.59), skin (≈1.52) and lung (≈1.50). RBEDSB variability between both sources was within 2%. A correlation was shown between RBEDSB and average photon energy and used to produce an RBEDSB map of a dose distribution in an APBI patient dataset. Radiation quality is very similar between electronic brachytherapy sources studied. No significant reductions in RBEDSB were observed with increasing distance from the source.

  3. Comparative investigation of the solution species [U(CO3)5]6- and the crystal structure of Na6[U(CO3)5].12H2O.

    PubMed

    Hennig, Christoph; Ikeda-Ohno, Atsushi; Emmerling, Fanziska; Kraus, Werner; Bernhard, Gert

    2010-04-21

    The limiting U(IV) carbonate species in aqueous solution was investigated by comparing its structure parameters with those of the complex preserved in a crystal structure. The solution species prevails in aqueous solution of 0.05 M U(IV) and 1 M NaHCO(3) at pH 8.3. Single crystals of Na(6)[U(CO(3))(5)].12H(2)O were obtained directly from this mother solution. The U(IV) carbonate complex in the crystal structure was identified as a monomeric [U(CO(3))(5)](6-) anionic complex. The interatomic distances around the U(IV) coordination polyhedron show average distances of U-O = 2.461(8) A, U-C = 2.912(4) A and U-O(dist) = 4.164(6) A. U L(3)-edge EXAFS spectra were collected from the solid Na(6)[U(CO(3))(5)].12H(2)O and the corresponding solution. The first shell of the Fourier transforms (FTs) revealed, in both samples, a coordination of ten oxygen atoms at an average U-O distance of 2.45 +/- 0.02 A, the second shell originates from five carbon atoms with a U-C distance of 2.91 +/- 0.02 A, and the third shell was fit with single and multiple scattering paths of the distal oxygen at 4.17 +/- 0.02 A. These data indicate the identity of the [U(CO(3))(5)](6-) complex in solid and solution state. The high negative charge of the [U(CO(3))(5)](6-) anion is compensated by Na(+) cations. In solid state the Na(+) cations form a bridging network between the [U(CO(3))(5)](6-) units, while in liquid state the Na(+) cations seem to be located close to the anionic complex. The average metal-oxygen distances of the coordination polyhedron show a linear correlation to the radius contraction of the neighbouring actinide(IV) ions and indicate the equivalence of the [An(CO(3))(5)](6-) coordination within the series of thorium, uranium, neptunium and plutonium.

  4. Regional propagation characteristics and source parameters of earthquakes in northeastern North America

    USGS Publications Warehouse

    Boatwright, John

    1994-01-01

    The vertical components of the S wave trains recorded on the Eastern Canadian Telemetered Network (ECTN) from 1980 through 1990 have been spectrally analyzed for source, site, and propagation characteristics. The data set comprises some 1033 recordings of 97 earthquakes whose magnitudes range from M ≈ 3 to 6. The epicentral distances range from 15 to 1000 km, with most of the data set recorded at distances from 200 to 800 km. The recorded S wave trains contain the phases S, SmS, Sn, and Lg and are sampled using windows that increase with distance; the acceleration spectra were analyzed from 1.0 to 10 Hz. To separate the source, site, and propagation characteristics, an inversion for the earthquake corner frequencies, low-frequency levels, and average attenuation parameters is alternated with a regression of residuals onto the set of stations and a grid of 14 distances ranging from 25 to 1000 km. The iteration between these two parts of the inversion converges in about 60 steps. The average attenuation parameters obtained from the inversion were Q = 1997 ± 10 and γ = 0.998 ± 0.003. The most pronounced variation from this average attenuation is a marked deamplification of more than a factor of 2 at 63 km and 2 Hz, which shallows with increasing frequency and increasing distance out to 200 km. The site-response spectra obtained for the ECTN stations are generally flat. The source spectral shape assumed in this inversion provides an adequate spectral model for the smaller events (Mo < 3 × 1021 dyne-cm) in the data set, whose Brune stress drops range from 5 to 150 bars. For the five events in the data set with Mo ≧ 1023 dyne-cm, however, the source spectra obtained by regressing the residuals suggest that an ω2 spectrum is an inadequate model for the spectral shape. In particular, the corner frequencies for most of these large events appear to be split, so that the spectra exhibit an intermediate behavior (where |ü(ω)| is roughly proportional to ω).

  5. Using anatomical landmark to avoid phrenic nerve injury during balloon-based procedures in atrial fibrillation patients.

    PubMed

    Smith, Nicolina M; Segars, Larry; Kauffman, Travis; Olinger, Anthony B

    2017-12-01

    Atrial fibrillation (AF) is an arrhythmia which affects as many as 2.7 million Americans. AF should be treated, because it can lead to a four-to-fivefold increased risk of experiencing a stroke. The American College of Cardiology/American Heart Association guidelines for the treatment of drug refractory and symptomatic paroxysmal AF denote catheter ablation as the standard of care. The newest ablation treatment, cryoballoon, uses a cold balloon tip. The biggest risk factor associated with the cryoballoon ablation is phrenic nerve injury (PNI). The purpose of this study is to measure relevant distances from specific landmarks to the right phrenic nerve (RPN) to create a safe zone for physicians. Using 30 cadaveric specimens, we measured laterally from the right superior pulmonary vein orifice (RSPV) to the RPN at the level of the sixth thoracic vertebra and laterally from the lateral border of the sixth thoracic vertebral body (T6) to the RPN. The depth and width of the left atrium (LA) were also measured to establish a cross-sectional area of the LA. The cross-sectional area of the LA was then correlated with the averaged measurements to see if the area of the LA could be a predictor of the location of the RPN. The average distance from the RPN-RSPV was 9.6 mm (range 4.3-18.8 mm). The average RPN-T6 distance was 30.6 mm (range 13.7-49.9 mm). There was a non-significant trend that suggests as the size of the LA increases, the measured distances also increased. Using the lateral border of the sixth thoracic vertebra as a landmark, which can be viewed under fluoroscopy during the procedure, physicians can triangulate the distance to the RSPV and determine the approximate position of the RPN. Furthermore, physicians can perform a preoperative echocardiogram to determine the size of the LA to assist in determining the position of the RPN with the hopes of avoiding injury to the RPN.

  6. Astrometry With the Hubble Space Telescope: Trigonometric Parallaxes of Planetary Nebula Nuclei NGC 6853, NGC 7293, ABELL 31, and DeHt 5

    NASA Technical Reports Server (NTRS)

    Benedict, G. F.; McArthur, Barbara E.; Napiwotzki, Ralf; Harrison, Thomas E.; Harris, Hugh C.; Nelan, Edmund; Bond, Howard E; Patterson, Richard J.; Ciardullo, Robin

    2009-01-01

    We present absolute parallaxes and relative proper motions for the central stars of the planetary nebulae NGC 6853 (The Dumbbell), NGC 7293 (The Helix), Abell 31, and DeHt 5. This paper details our reduction and analysis using DeHt 5 as an example. We obtain these planetary nebula nuclei (PNNi) parallaxes with astrometric data from Fine Guidance Sensors FGS 1r and FGS 3, white-light interferometers on the Hubble Space Telescope. Proper motions, spectral classifications and VJHKT2M and DDO51 photometry of the stars comprising the astrometric reference frames provide spectrophotometric estimates of reference star absolute parallaxes. Introducing these into our model as observations with error, we determine absolute parallaxes for each PNN. Weighted averaging with previous independent parallax measurements yields an average parallax precision, sigma (sub pi)/ pi = 5%. Derived distances are: d(sub NGC6853) = 405(exp +28 sub -25) pc, d(sub NGC7293) = 216(exp +14 sub -12) pc, d(sub Abell31) = 621(exp +91 sub -70) pc, and d(sub DeHt5) = 345(exp +19 sub -17) pc. These PNNi distances are all smaller than previously derived from spectroscopic analyses of the central stars. To obtain absolute magnitudes from these distances requires estimates of interstellar extinction. We average extinction measurements culled from the literature, from reddening based on PNNi intrinsic colors derived from model SEDs, and an assumption that each PNN experiences the same rate of extinction as a function of distance as do the reference stars nearest (in angular separation) to each central star. We also apply Lutz-Kelker bias corrections. The absolute magnitudes and effective temperatures permit estimates of PNNi radii through both the Stefan-Boltzmann relation and Eddington fluxes. Comparing absolute magnitudes with post-AGB models provides mass estimates. Masses cluster around 0.57 solar Mass, close to the peak of the white dwarf mass distribution. Adding a few more PNNi with well-determined distances and masses, we compare all the PNNi with cooler white dwarfs of similar mass, and confirm, as expected, that PNNi have larger radii than white dwarfs that have reached their final cooling tracks.

  7. Properties of a new small-world network with spatially biased random shortcuts

    NASA Astrophysics Data System (ADS)

    Matsuzawa, Ryo; Tanimoto, Jun; Fukuda, Eriko

    2017-11-01

    This paper introduces a small-world (SW) network with a power-law distance distribution that differs from conventional models in that it uses completely random shortcuts. By incorporating spatial constraints, we analyze the divergence of the proposed model from conventional models in terms of fundamental network properties such as clustering coefficient, average path length, and degree distribution. We find that when the spatial constraint more strongly prohibits a long shortcut, the clustering coefficient is improved and the average path length increases. We also analyze the spatial prisoner's dilemma (SPD) games played on our new SW network in order to understand its dynamical characteristics. Depending on the basis graph, i.e., whether it is a one-dimensional ring or a two-dimensional lattice, and the parameter controlling the prohibition of long-distance shortcuts, the emergent results can vastly differ.

  8. 2- to 3-kHz continuum emissions as possible indications of global heliospheric 'breathing'

    NASA Technical Reports Server (NTRS)

    Grzedzielski, S.; Lazarus, A. J.

    1993-01-01

    The paper analyzes the main features of 2- to 3-kHz heliospheric emissions in the context of a general heliospheric 'breathing' as inferred from the Voyager 2 solar wind average ram pressure data. Triggers for the three 3-kHz emission events seen to date are suggested, and good agreement is obtained in timing and expected postshock frequency for termination shock distances of about 90 AU. It is suggested that the visibility of the individual 3-kHz events and their observed upward frequency drift are enhanced when the postulated global heliospheric expansion results in the formation of a transient, compressed external plasma barrier around the heliopause that prevents radiation escape for several months. The average termination shock distance is estimated to be in the range 80-90 AU.

  9. Streamwise Versus Spanwise Spacing of Obstacle Arrays: Parametrization of the Effects on Drag and Turbulence

    NASA Astrophysics Data System (ADS)

    Simón-Moral, Andres; Santiago, Jose Luis; Krayenhoff, E. Scott; Martilli, Alberto

    2014-06-01

    A Reynolds-averaged Navier-Stokes model is used to investigate the evolution of the sectional drag coefficient and turbulent length scales with the layouts of aligned arrays of cubes. Results show that the sectional drag coefficient is determined by the non-dimensional streamwise distance (sheltering parameter), and the non-dimensional spanwise distance (channelling parameter) between obstacles. This is different than previous approaches that consider only plan area density . On the other hand, turbulent length scales behave similarly to the staggered case (e. g. they are function of only). Analytical formulae are proposed for the length scales and for the sectional drag coefficient as a function of sheltering and channelling parameters, and implemented in a column model. This approach demonstrates good skill in the prediction of vertical profiles of the spatially-averaged horizontal wind speed.

  10. Evaluation of bone surrogates for indirect and direct ballistic fractures.

    PubMed

    Bir, Cynthia; Andrecovich, Chris; DeMaio, Marlene; Dougherty, Paul J

    2016-04-01

    The mechanism of injury for fractures to long bones has been studied for both direct ballistic loading as well as indirect. However, the majority of these studies have been conducted on both post-mortem human subjects (PMHS) and animal surrogates which have constraints in terms of storage, preparation and testing. The identification of a validated bone surrogate for use in forensic, medical and engineering testing would provide the ability to investigate ballistic loading without these constraints. Two specific bone surrogates, Sawbones and Synbone, were evaluated in comparison to PMHS for both direct and indirect ballistic loading. For the direct loading, the mean velocity to produce fracture was 121 ± 19 m/s for the PMHS, which was statistically different from the Sawbones (140 ± 7 m/s) and Synbone (146 ± 3 m/s). The average distance to fracture in the indirect loading was .70 cm for the PMHS. The Synbone had a statistically similar average distance to fracture (.61 cm, p=0.54) however the Sawbones average distance to fracture was statistically different (.41 cm, p<0.05). Fractures patterns were found to be comparable to the PMHS for tests conducted with Synbones, however the input parameters were slightly varied to produce similar results. The fractures patterns with the Sawbones were not found to be as comparable to the PMHS. An ideal bone surrogate for ballistic testing was not identified and future work is warranted. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. [Spatial analysis of road traffic accidents with fatalities in Spain, 2008-2011].

    PubMed

    Gómez-Barroso, Diana; López-Cuadrado, Teresa; Llácer, Alicia; Palmera Suárez, Rocío; Fernández-Cuenca, Rafael

    2015-09-01

    To estimate the areas of greatest density of road traffic accidents with fatalities at 24 hours per km(2)/year in Spain from 2008 to 2011, using a geographic information system. Accidents were geocodified using the road and kilometer points where they occurred. The average nearest neighbor was calculated to detect possible clusters and to obtain the bandwidth for kernel density estimation. A total of 4775 accidents were analyzed, of which 73.3% occurred on conventional roads. The estimated average distance between accidents was 1,242 meters, and the average expected distance was 10,738 meters. The nearest neighbor index was 0.11, indicating that there were aggregations of accidents in space. A map showing the kernel density was obtained with a resolution of 1 km(2), which identified the areas of highest density. This methodology allowed a better approximation to locating accident risks by taking into account kilometer points. The map shows areas where there was a greater density of accidents. This could be an advantage in decision-making by the relevant authorities. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  12. Genome size variation in the genus Avena.

    PubMed

    Yan, Honghai; Martin, Sara L; Bekele, Wubishet A; Latta, Robert G; Diederichsen, Axel; Peng, Yuanying; Tinker, Nicholas A

    2016-03-01

    Genome size is an indicator of evolutionary distance and a metric for genome characterization. Here, we report accurate estimates of genome size in 99 accessions from 26 species of Avena. We demonstrate that the average genome size of C genome diploid species (2C = 10.26 pg) is 15% larger than that of A genome species (2C = 8.95 pg), and that this difference likely accounts for a progression of size among tetraploid species, where AB < AC < CC (average 2C = 16.76, 18.60, and 21.78 pg, respectively). All accessions from three hexaploid species with the ACD genome configuration had similar genome sizes (average 2C = 25.74 pg). Genome size was mostly consistent within species and in general agreement with current information about evolutionary distance among species. Results also suggest that most of the polyploid species in Avena have experienced genome downsizing in relation to their diploid progenitors. Genome size measurements could provide additional quality control for species identification in germplasm collections, especially in cases where diploid and polyploid species have similar morphology.

  13. [Diagnosis of electron energy and comparative effects of OH, O or O3 on NO oxidation in pulsed corona discharge].

    PubMed

    Xuan, Jian-yong; Luo, Zhong-yang; Zhao, Lei; Jiang, Jian-ping; Gao, Xiang

    2012-05-01

    The spectrum of excited N2 molecules and ions was measured by optical emission spectroscopy in pulsed corona discharge with a wire-to-plate reactor. The ratio of emission intensities emitted by the excited molecules and ions of N2 was compared with numerical simulation to determine average electron energies and electric field distributions. Within 2 cm distance from wire electrode in horizontal and vertical directions, electric field and average electron energies appear to be in the ranges of 11.05 19.6 MV x m(-1) and 10.10-13.92 eV respectively; as the distance increases, average electron energies and electric field show a similar trend: first decrease and then increase. Chemically active species, such as OH, O and O3, can be generated through the energetic electron collisions with H2O and O2 directly or indirectly. For the NO oxidation, there is no coexistence of NO and O3, whereas there is a coexistence of NO and OH. NO is oxidized by O3 or O more efficiently than by OH radical.

  14. Optical frequency transfer via a 660 km underground fiber link using a remote Brillouin amplifier.

    PubMed

    Raupach, S M F; Koczwara, A; Grosche, G

    2014-11-03

    In long-distance, optical continuous-wave frequency transfer via fiber, remote bidirectional Er³ ⁺ -doped fiber amplifiers are commonly used to mitigate signal attenuation. We demonstrate for the first time the ultrastable transfer of an optical frequency using a remote fiber Brillouin amplifier, placed in a server room along the link. Using it as the only means of remote amplification, on a 660 km loop of installed underground fiber we bridge distances of 250 km and 160 km between amplifications. Over several days of uninterrupted measurement, we find an instability of the frequency transfer (Allan deviation of Λ-weighted data with 1 s gate time) of around 1 × 10(-19) and less for averaging times longer than 3000 s. The modified Allan deviation reaches 3 × 10(-19) at an averaging time of 100 s. Beyond 100 s it follows the interferometer noise floor, and for averaging times longer than 1000 s the modified Allan deviation is in the 10(-20) range. A conservative value of the overall accuracy is 1 × 10(-19)

  15. The possibility of applying spectral redundancy in DWDM systems on existing long-distance FOCLs for increasing the data transmission rate and decreasing nonlinear effects and double Rayleigh scattering without changes in the communication channel

    NASA Astrophysics Data System (ADS)

    Nekuchaev, A. O.; Shuteev, S. A.

    2014-04-01

    A new method of data transmission in DWDM systems along existing long-distance fiber-optic communication lines is proposed. The existing method, e.g., uses 32 wavelengths in the NRZ code with an average power of 16 conventional units (16 units and 16 zeros on the average) and transmission of 32 bits/cycle. In the new method, one of 124 wavelengths with a duration of one cycle each (at any time instant, no more than 16 obligatory different wavelengths) and capacity of 4 bits with an average power of 15 conventional units and rate of 64 bits/cycle is transmitted at every instant of a 1/16 cycle. The cross modulation and double Rayleigh scattering are significantly decreased owing to uniform distribution of power over time at different wavelengths. The time redundancy (forward error correction (FEC)) is about 7% and allows one to achieve a coding enhancement of about 6 dB by detecting and removing deletions and errors simultaneously.

  16. Unraveling the Tangles of Language Evolution

    NASA Astrophysics Data System (ADS)

    Petroni, F.; Serva, M.; Volchenkov, D.

    2012-07-01

    The relationships between languages molded by extremely complex social, cultural and political factors are assessed by an automated method, in which the distance between languages is estimated by the average normalized Levenshtein distance between words from the list of 200 meanings maximally resistant to change. A sequential process of language classification described by random walks on the matrix of lexical distances allows to represent complex relationships between languages geometrically, in terms of distances and angles. We have tested the method on a sample of 50 Indo-European and 50 Austronesian languages. The geometric representations of language taxonomy allows for making accurate interfaces on the most significant events of human history by tracing changes in language families through time. The Anatolian and Kurgan hypothesis of the Indo-European origin and the "express train" model of the Polynesian origin are thoroughly discussed.

  17. Evaluating Cumulative Ascent:. Mountain Biking Meets Mandelbrot

    NASA Astrophysics Data System (ADS)

    Rapaport, D. C.

    The problem of determining total distance ascended during a mountain bike trip is addressed. Altitude measurements are obtained from GPS receivers utilizing both GPS-based and barometric altitude data, with data averaging used to reduce fluctuations. The estimation process is sensitive to the degree of averaging, and is related to the well-known question of determining coastline length. Barometric-based measurements prove more reliable, due to their insensitivity to GPS altitude fluctuations.

  18. Accuracy and precision of 3D cephalometric landmarks from biorthogonal plain-film x rays

    NASA Astrophysics Data System (ADS)

    Dean, David; Palomo, Martin; Subramanyan, Krishna; Hans, Mark G.; Broadbent, B. H., Jr.; Moullas, Alexander; Macaraeg, Omar

    1998-06-01

    Three dimensional (3D) plain film radiographic cephalometric analysis of boney skull landmarks may be used for patient diagnosis, treatment planning, prosthetic design, intra- operatively, and outcome assessment. To test the accuracy and reliability of 50 cephalometric landmarks, three dry human skulls, with and without metallic markers affixed to the landmarks, were digitized in our 3dCEPH software by 4 operators. The average inter-operator variability about mean landmark position, across all operators, for all 3 skull image pairs, was 3.33 mm. Ten landmarks exhibiting least variability were 1.15 mm average distance from the mean, including: B point 0.69 mm, Lower Incisal Edge 0.85 mm, and Anterior Nasal Spine 0.90 mm. The average rms error from the metallic fiducials for these 4 operators across all 50 landmarks, and 3 skulls was 5.03 mm. The 10 landmarks with the least variability exhibited 2.01 mm average distance from the fiducial, including: B point 1.69 mm, upper incisal edge 1.71 mm, lower incisal edge 1.78 mm. Additional studies are needed to test the robusticity of the hypothesis of homologous anatomy. Homology of landmarks is important to cephalometric comparisons between image pairs representing patient and 'normative,' pre- and post-surgical alteration, and different ages of the same patient.

  19. Development and verification of a novel device for dental intra-oral 3D scanning using chromatic confocal technology

    NASA Astrophysics Data System (ADS)

    Zint, M.; Stock, K.; Graser, R.; Ertl, T.; Brauer, E.; Heyninck, J.; Vanbiervliet, J.; Dhondt, S.; De Ceuninck, P.; Hibst, R.

    2015-03-01

    The presented work describes the development and verification of a novel optical, powder-free intra-oral scanner based on chromatic confocal technology combined with a multifocal approach. The proof of concept for a chromatic confocal area scanner for intra-oral scanning is given. Several prototype scanners passed a verification process showing an average accuracy (distance deviation on flat surfaces) of less than 31μm +/- 21μm and a reproducibility of less than 4μm +/- 3μm. Compared to a tactile measurement on a full jaw model fitted with 4mm ceramic spheres the measured average distance deviation between the spheres was 49μm +/- 12μm for scans of up to 8 teeth (3- unit bridge, single Quadrant) and 104μm +/- 82μm for larger scans and full jaws. The average deviation of the measured sphere diameter compared to the tactile measurement was 27μm +/- 14μm. Compared to μCT scans of plaster models equipped with human teeth the average standard deviation on up to 3 units was less than 55μm +/- 49μm whereas the reproducibility of the scans was better than 22μm +/- 10μm.

  20. Distance and slope constraints: adaptation and variability in golf putting.

    PubMed

    Dias, Gonçalo; Couceiro, Micael S; Barreiros, João; Clemente, Filipe M; Mendes, Rui; Martins, Fernando M

    2014-07-01

    The main objective of this study is to understand the adaptation to external constraints and the effects of variability in a golf putting task. We describe the adaptation of relevant variables of golf putting to the distance to the hole and to the addition of a slope. The sample consisted of 10 adult male (33.80 ± 11.89 years), volunteers, right handed and highly skilled golfers with an average handicap of 10.82. Each player performed 30 putts at distances of 2, 3 and 4 meters (90 trials in Condition 1). The participants also performed 90 trials, at the same distances, with a constraint imposed by a slope (Condition 2). The results indicate that the players change some parameters to adjust to the task constraints, namely the duration of the backswing phase, the speed of the club head and the acceleration at the moment of impact with the ball. The effects of different golf putting distances in the no-slope condition on different kinematic variables suggest a linear adjustment to distance variation that was not observed when in the slope condition.

  1. The visual perception of distance ratios in physical space.

    PubMed

    Norman, J Farley; Adkins, Olivia C; Pedersen, Lauren E

    2016-06-01

    Past studies have consistently demonstrated that human observers cannot accurately perceive environmental distances. Even so, we obviously detect sufficient spatial information to meet the demands of everyday life. In the current experiment, ten younger adults (mean age was 21.8years) and ten older adults (mean age was 72.3years) estimated distance ratios in physical space. On any given trial, observers judged how long one distance interval was relative to another. The 18 stimulus ratios ranged from 1.0 to 9.5; the observers judged each stimulus ratio three times. The average correlation coefficient relating actual distance ratios to perceived ratios was identical (r=0.87) for both younger and older age groups. Despite this strong relationship between perception and reality, the judgments of many individual observers were inaccurate. For example, ten percent of the observers overestimated the stimulus ratios, while fifty percent underestimated the stimulus ratios. Although both under- and overestimation occurred in the current experiment, the results nevertheless demonstrate that human adults can reliably compare environmental distances in different directions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Estimated metabolic and mechanical demands during different small-sided games in elite soccer players.

    PubMed

    Gaudino, Paolo; Alberti, Giampietro; Iaia, F Marcello

    2014-08-01

    The present study examined the extent to which game format (possession play, SSG-P and game with regular goals and goalkeepers, SSG-G) and the number of players (5, 7 and 10 a-side) influence the physical demands of small-sided soccer games (SSGs) in elite soccer players. Training data were collected during the in-season period from 26 English Premier League outfield players using global positioning system technology. Total distance covered, distance at different speed categories and maximal speed were calculated. In addition, we focused on changes in velocity by reporting the number of accelerations and decelerations carried out during the SSGs (divided in two categories: moderate and high) and the absolute maximal values of acceleration and deceleration achieved. By taking into account these parameters besides speed and distance values, estimated energy expenditure and average metabolic power and distance covered at different metabolic power categories were calculated. All variables were normalized by time (i.e., 4min). The main findings were that the total distance, distances run at high speed (>14.4kmh(-1)) as well as absolute maximum velocity, maximum acceleration and maximum deceleration increased with pitch size (10v10>7v7>5v5; p<.05). Furthermore, total distance, very high (19.8-25.2kmh(-1)) and maximal (>25.2kmh(-1)) speed distances, absolute maximal velocity and maximum acceleration and deceleration were higher in SSG-G than in SSG-P (p<.001). On the other hand, the number of moderate (2-3ms(-2)) accelerations and decelerations as well as the total number of changes in velocity were greater as the pitch dimensions decreased (i.e., 5v5>7v7>10v10; p<.001) in both SSG-G and SSG-P. In addition, predicted energy cost, average metabolic power and distance covered at every metabolic power categories were higher in SSG-P compared to SSG-G and in big than in small pitch areas (p<.05). A detailed analysis of these drills is pivotal in contemporary football as it enables an in depth understanding of the workload imposed on each player which consequently has practical implications for the prescription of the adequate type and amount of stimulus during exercise training. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. The wild flora biodiversity in pesticide free bufferzones along old hedgerows.

    PubMed

    Andresen, L C; Nothlev, J; Kristensen, K; Navntoft, S; Johnsen, I

    2012-05-01

    The natural field margin ecotone from the field border and into a cropped field hosts a diversity of plant species. In conventional cropped fields, biodiversity suffers from fertilizer and pesticide application. In our study at Danish conventional spring-barley fields, we laid out bufferzones with no pesticide application spraying after sowing, with the widths: 24, 12, 6 and 4 m (and control) to the field edge hedgerow. Through one season: plant species number, biodiversity and evenness for each bufferzone at the distances: 18, 9, 5, 2 and 0 m from the hedgerow were significantly affected by distance to the hedge and by width of bufferzone. The bufferzones affected: species number (total of 92 weed species), species diversity (1.27 to 0.44) and species evenness index (0.63 to 0.87), and revealed that the bufferzone of 24 m gave the largest improvementof the field margin for plants. Decreasing the bufferzone widths provided smaller biodiversity and larger evenness of plants at distances larger than the buffer width: the distance at which diversity (Shannons) was reduced by half the difference between hedge- and field diversity was 1.2, 3.1, 6.7, 10.8 and 10.9 m in bufferwidth treatments of 0, 4, 6, 12 and 24 m; likewise, the half-way distance for Smiths and Wilsons evenness index was 1.2, 1.7, 5.4, 14.0 and 30.2 m in the bufferwidth treatments of 0, 4, 6,12 and 24 m. Based on modelled diversity and evenness indexes a positive effect of buffer was evident from 6 m bufferzone. The average diversity over the distances from 0 to 18 m was 0.66, 0.75, 0.98, 1.14 and 1.11 in bufferwidth treatments of 0, 4, 6, 12 and 24 m and the average evenness over the distances from 0 to 18 m was 0.82, 0.80, 0.74, 0.66 and 0.63, in bufferwidth treatments of 0, 4, 6, 12 and 24 m. Furthermore, the accumulated number of species revealed that a bufferzone width of at least 6 m was needed to significantly increase the species richness at all distances between 2 and 18 m. At 18 m distance, the accumulated number of species was 37.1, 39.7, 41.2, 42.4 and 42.7 in bufferwidth treatments of 0, 4, 6, 12 and 24 m.

  4. VizieR Online Data Catalog: Star clusters distances and extinctions (Buckner+, 2013)

    NASA Astrophysics Data System (ADS)

    Buckner, A. S. M.; Froebrich, D.

    2014-10-01

    Determining star cluster distances is essential to analyse their properties and distribution in the Galaxy. In particular, it is desirable to have a reliable, purely photometric distance estimation method for large samples of newly discovered cluster candidates e.g. from the Two Micron All Sky Survey, the UK Infrared Deep Sky Survey Galactic Plane Survey and VVV. Here, we establish an automatic method to estimate distances and reddening from near-infrared photometry alone, without the use of isochrone fitting. We employ a decontamination procedure of JHK photometry to determine the density of stars foreground to clusters and a galactic model to estimate distances. We then calibrate the method using clusters with known properties. This allows us to establish distance estimates with better than 40 percent accuracy. We apply our method to determine the extinction and distance values to 378 known open clusters and 397 cluster candidates from the list of Froebrich, Scholz & Raftery (2007MNRAS.374..399F, Cat. J/MNRAS/374/399). We find that the sample is biased towards clusters of a distance of approximately 3kpc, with typical distances between 2 and 6kpc. Using the cluster distances and extinction values, we investigate how the average extinction per kiloparsec distance changes as a function of the Galactic longitude. We find a systematic dependence that can be approximated by AH(l)[mag/kpc]=0.10+0.001x|l-180°|/° for regions more than 60° from the Galactic Centre. (1 data file).

  5. Ensemble Weight Enumerators for Protograph LDPC Codes

    NASA Technical Reports Server (NTRS)

    Divsalar, Dariush

    2006-01-01

    Recently LDPC codes with projected graph, or protograph structures have been proposed. In this paper, finite length ensemble weight enumerators for LDPC codes with protograph structures are obtained. Asymptotic results are derived as the block size goes to infinity. In particular we are interested in obtaining ensemble average weight enumerators for protograph LDPC codes which have minimum distance that grows linearly with block size. As with irregular ensembles, linear minimum distance property is sensitive to the proportion of degree-2 variable nodes. In this paper the derived results on ensemble weight enumerators show that linear minimum distance condition on degree distribution of unstructured irregular LDPC codes is a sufficient but not a necessary condition for protograph LDPC codes.

  6. [Health risks of long-distance air travel. Role of the general practitioner].

    PubMed

    Bazex, Jacques; Cabanis, Emmanuel Alain

    2010-06-01

    Air transport is seeing an increase in long-distance flights (12-16 hours average flight time), greater seating capacity, and a higher proportion of elderly, and hence more fragile, passengers. The French Academy of Medicine recommends that medical care be reinforced, particularly on long-distance flights, through the following measures: (i) passengers should be informed in advance of potential risks, through a Passenger's Guide, (ii) all future passengers should be encouraged to seek health advice and information from their general practitioner, (iii) flight crew members should receive training as "in-flight medical correspondents", and (iv) airlines and plane designers should reserve a "medical space" on the plane, equipped with appropriate medical materials.

  7. [Onyx embolization for treatment of dural arteriovenous fistula: comparison of long- distance versus routine injection method].

    PubMed

    He, Xiao-Yan; Zhang, Guo-Zhong; Li, Ming-Zhou; Wang, Gang; Liu, Dan; Qi, Song-Tao; Li, Wei-Guang; Feng, Wen-Feng

    2016-03-01

    To compare the efficacy, clinical characteristics, safety, injection time and radiation exposure of Onyx embolization using a long-distance injection method and routine injection method for management of dural arteriovenous fistula (DAVF). The clinical data were retrospectively analyzed in 59 patients with DAVF treated with Onyx embolization using long-distance injection method (28 patients) and routine injection method (31 patients). The efficacy, safety, injection time and radiation exposure during Onyx embolization were compared between the two injections methods. The average radiation dose exposure to the surgeon per procedure was significantly lower in the long-distance injection group than in the routine group. The injection time (P=0.53), injection volume (P=0.78), number of supply arteries (P=0.80), Cognard types (P=0.67), and effect of embolization (P=0.88) were all similar between the two groups. Endovaseular treatment of intracranial DAVF with Onyx embolization using the long-distance injection method is feasible, safe and effective and can reduce the radiation exposure to the surgeon.

  8. Post-release survival and movement of Western Grebes (Aechmophorus occidentalis) implanted with intracoelomic satellite transmitters

    USGS Publications Warehouse

    Mills, Kyra L.; Gaydos, Joseph K.; Fiorello, Christine V.; Whitmer, Emily; De La Cruz, Susan; Mulcahy, Daniel M.; Vilchis, L. Ignacio; Ziccardi, Michael H.

    2016-01-01

    The main goal of this study was to gain knowledge on post-release survival and movement of Western Grebes (Aechmophorus occidentalis) using a modified technique for implanting satellite transmitters. This technique had improved post-surgical survival in an earlier study. Nine Western Grebes, implanted with intracoelomic (within the body cavity) satellite transmitters with percutaneous antennae, were released close to their capture site in San Francisco Bay, California, USA. Eight survived at least 25 days (average number of transmittal days was 140.8), while two had transmitters that provided data for greater than 1 year (436 and 454 days). The average cumulative distance recorded for all Western Grebes (n = 9) was 829 km with two round-trip movements documented. One individual Western Grebe traveled a cumulative round-trip distance of 2,144 km in July and November 2011, while another individual traveled a round-trip distance of 1,514 km between 8 and 14 December 2011. This study provides a step forward in testing implantable satellite transmitters in Western Grebes and highlights the need to further improve tracking methods, potentially improving our understanding of their population threats.

  9. Structural study of the ammonium octafluoroneptunate, [NH 4] 4NpF 8

    DOE PAGES

    Poineau, Frederic; Silva, Chinthaka M.; Yeamans, Charles B.; ...

    2016-04-21

    The [NH 4] 4NpF 8 salt was prepared from the solid-state reaction of NpO 2 with NH 4HF 2 and characterized by powder X-ray diffraction and X-ray absorption fine structure spectroscopy. The diffraction results confirm the compound to be isostructural to [NH 4] 4UF 8 with the following lattice parameter (a = 13.054(4) Å, b = 6.681(2) Å, c = 13.676(5) Å, ß = 121.14 Å). For the first time, a Neptunium fluoride complex has been characterized by XAFS spectroscopy. The energy position of the white line and inflection of the XANES spectra of [NH 4] 4NpF 8 are consistentmore » with the presence of Np(IV). Adjustment of the EXAFS spectra indicates that the coordination number (7.4±1.5) and the average Np-F distance (2.26(1) Å) are consistent with the presence of the NpF8 dodecahedron. The average Np-F distance is ~0.02 Å shorter than the U-F distance in [NH 4] 4UF 8 and is a result of the actinide contraction.« less

  10. Quantifying Nucleic Acid Ensembles with X-ray Scattering Interferometry.

    PubMed

    Shi, Xuesong; Bonilla, Steve; Herschlag, Daniel; Harbury, Pehr

    2015-01-01

    The conformational ensemble of a macromolecule is the complete description of the macromolecule's solution structures and can reveal important aspects of macromolecular folding, recognition, and function. However, most experimental approaches determine an average or predominant structure, or follow transitions between states that each can only be described by an average structure. Ensembles have been extremely difficult to experimentally characterize. We present the unique advantages and capabilities of a new biophysical technique, X-ray scattering interferometry (XSI), for probing and quantifying structural ensembles. XSI measures the interference of scattered waves from two heavy metal probes attached site specifically to a macromolecule. A Fourier transform of the interference pattern gives the fractional abundance of different probe separations directly representing the multiple conformation states populated by the macromolecule. These probe-probe distance distributions can then be used to define the structural ensemble of the macromolecule. XSI provides accurate, calibrated distance in a model-independent fashion with angstrom scale sensitivity in distances. XSI data can be compared in a straightforward manner to atomic coordinates determined experimentally or predicted by molecular dynamics simulations. We describe the conceptual framework for XSI and provide a detailed protocol for carrying out an XSI experiment. © 2015 Elsevier Inc. All rights reserved.

  11. Automatic Approach for Lung Segmentation with Juxta-Pleural Nodules from Thoracic CT Based on Contour Tracing and Correction.

    PubMed

    Wang, Jinke; Guo, Haoyan

    2016-01-01

    This paper presents a fully automatic framework for lung segmentation, in which juxta-pleural nodule problem is brought into strong focus. The proposed scheme consists of three phases: skin boundary detection, rough segmentation of lung contour, and pulmonary parenchyma refinement. Firstly, chest skin boundary is extracted through image aligning, morphology operation, and connective region analysis. Secondly, diagonal-based border tracing is implemented for lung contour segmentation, with maximum cost path algorithm used for separating the left and right lungs. Finally, by arc-based border smoothing and concave-based border correction, the refined pulmonary parenchyma is obtained. The proposed scheme is evaluated on 45 volumes of chest scans, with volume difference (VD) 11.15 ± 69.63 cm 3 , volume overlap error (VOE) 3.5057 ± 1.3719%, average surface distance (ASD) 0.7917 ± 0.2741 mm, root mean square distance (RMSD) 1.6957 ± 0.6568 mm, maximum symmetric absolute surface distance (MSD) 21.3430 ± 8.1743 mm, and average time-cost 2 seconds per image. The preliminary results on accuracy and complexity prove that our scheme is a promising tool for lung segmentation with juxta-pleural nodules.

  12. Effect of pillow height on the biomechanics of the head-neck complex: investigation of the cranio-cervical pressure and cervical spine alignment

    PubMed Central

    Yang, Hui; Zhou, Yan; Lin, Jin

    2016-01-01

    Background While appropriate pillow height is crucial to maintaining the quality of sleep and overall health, there are no universal, evidence-based guidelines for pillow design or selection. We aimed to evaluate the effect of pillow height on cranio-cervical pressure and cervical spine alignment. Methods Ten healthy subjects (five males) aged 26 ± 3.6 years were recruited. The average height, weight, and neck length were 167 ± 9.3 cm, 59.6 ± 11.9 kg, and 12.9 ± 1.2 cm respectively. The subjects lay on pillows of four different heights (H0, 110 mm; H1, 130 mm; H2, 150 mm; and H3, 170 mm). The cranio-cervical pressure distribution over the pillow was recorded; the peak and average pressures for each pillow height were compared by one-way ANOVA with repeated measures. Cervical spine alignment was studied using a finite element model constructed based on data from the Visible Human Project. The coordinate of the center of each cervical vertebra were predicted for each pillow height. Three spine alignment parameters (cervical angle, lordosis distance and kyphosis distance) were identified. Results The average cranial pressure at pillow height H3 was approximately 30% higher than that at H0, and significantly different from those at H1 and H2 (p < 0.05). The average cervical pressure at pillow height H0 was 65% lower than that at H3, and significantly different from those at H1 and H2 (p < 0.05). The peak cervical pressures at pillow heights H2 and H3 were significantly different from that at H0 (p < 0.05). With respect to cervical spine alignment, raising pillow height from H0 to H3 caused an increase of 66.4% and 25.1% in cervical angle and lordosis distance, respectively, and a reduction of 43.4% in kyphosis distance. Discussion Pillow height elevation significantly increased the average and peak pressures of the cranial and cervical regions, and increased the extension and lordosis of the cervical spine. The cranio-cervical pressures and cervical spine alignment were height-specific, and they were believed to reflect quality of sleep. Our results provide a quantitative and objective evaluation of the effect of pillow height on the biomechanics of the head-neck complex, and have application in pillow design and selection. PMID:27635354

  13. Why GPS makes distances bigger than they are

    PubMed Central

    Ranacher, Peter; Brunauer, Richard; Trutschnig, Wolfgang; Van der Spek, Stefan; Reich, Siegfried

    2016-01-01

    ABSTRACT Global navigation satellite systems such as the Global Positioning System (GPS) is one of the most important sensors for movement analysis. GPS is widely used to record the trajectories of vehicles, animals and human beings. However, all GPS movement data are affected by both measurement and interpolation errors. In this article we show that measurement error causes a systematic bias in distances recorded with a GPS; the distance between two points recorded with a GPS is – on average – bigger than the true distance between these points. This systematic ‘overestimation of distance’ becomes relevant if the influence of interpolation error can be neglected, which in practice is the case for movement sampled at high frequencies. We provide a mathematical explanation of this phenomenon and illustrate that it functionally depends on the autocorrelation of GPS measurement error (C). We argue that C can be interpreted as a quality measure for movement data recorded with a GPS. If there is a strong autocorrelation between any two consecutive position estimates, they have very similar error. This error cancels out when average speed, distance or direction is calculated along the trajectory. Based on our theoretical findings we introduce a novel approach to determine C in real-world GPS movement data sampled at high frequencies. We apply our approach to pedestrian trajectories and car trajectories. We found that the measurement error in the data was strongly spatially and temporally autocorrelated and give a quality estimate of the data. Most importantly, our findings are not limited to GPS alone. The systematic bias and its implications are bound to occur in any movement data collected with absolute positioning if interpolation error can be neglected. PMID:27019610

  14. The effect of external non-driving factors, payment type and waiting and queuing on fatigue in long distance trucking.

    PubMed

    Williamson, Ann; Friswell, Rena

    2013-09-01

    The aim of this study was to explore the effects of external influences on long distance trucking, in particular, incentive-based remuneration systems and the need to wait or queue to load or unload on driver experiences of fatigue. Long distance truck drivers (n=475) were recruited at truck rest stops on the major transport corridors within New South Wales, Australia and asked to complete a survey by self-administration or interview. The survey covered demographics, usual working arrangements, details of the last trip and safety outcomes including fatigue experiences. On average drivers' last trip was over 2000 km and took 21.5 h to complete with an additional 6h of non-driving work. Incentive payments were associated with longer working hours, greater distances driven and higher fatigue for more drivers. Drivers required to wait in queues did significantly more non-driving work and experienced fatigue more often than those who did not. Drivers who were not paid to wait did the longest trips with average weekly hours above the legal working hours limits, had the highest levels of fatigue and the highest levels of interference by work with family life. In contrast, drivers who were paid to wait did significantly less work with shorter usual hours and shorter last trips. Multivariate analysis showed that incentive-based payment and unpaid waiting in queues were significant predictors of driver fatigue. The findings suggest that mandating payment of drivers for non-driving work including waiting would reduce the amount of non-driving work required for drivers and reduce weekly hours of work. In turn this would reduce driver fatigue and safety risk as well as enhancing the efficiency of the long distance road transport industry. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Novae as distance indicators

    NASA Technical Reports Server (NTRS)

    Ford, Holland C.; Ciardullo, Robin

    1988-01-01

    Nova shells are characteristically prolate with equatorial bands and polar caps. Failure to account for the geometry can lead to large errors in expansion parallaxes for individual novae. When simple prescriptions are used for deriving expansion parallaxes from an ensemble of randomly oriented prolate spheroids, the average distance will be too small by factors of 10 to 15 percent. The absolute magnitudes of the novae will be underestimated and the resulting distance scale will be too small by the same factors. If observations of partially resolved nova shells select for large inclinations, the systematic error in the resulting distance scale could easily be 20 to 30 percent. Extinction by dust in the bulge of M31 may broaden and shift the intrinsic distribution of maximum nova magnitudes versus decay rates. We investigated this possibility by projecting Arp's and Rosino's novae onto a composite B - 6200A color map of M31's bulge. Thirty two of the 86 novae projected onto a smooth background with no underlying structure due to the presence of a dust cloud along the line of sight. The distribution of maximum magnitudes versus fade rates for these unreddened novae is indistinguishable from the distribution for the entire set of novae. It is concluded that novae suffer very little extinction from the filamentary and patchy distribution of dust seen in the bulge of M31. Time average B and H alpha nova luminosity functions are potentially powerful new ways to use novae as standard candles. Modern CCD observations and the photographic light curves of M31 novae found during the last 60 years were analyzed to show that these functions are power laws. Consequently, unless the eruption times for novae are known, the data cannot be used to obtain distances.

  16. Consideration of driver home county prohibition and alcohol-related vehicle crashes.

    PubMed

    Schulte Gary, Sarah Lynn; Aultman-Hall, Lisa; McCourt, Matt; Stamatiadis, Nick

    2003-09-01

    This study examines the characteristics of alcohol-related crashes in wet versus dry counties in the state of Kentucky, USA and incorporates the location of driver residences through use of geographic information system (GIS) analysis. Between 1991 and 1997, 39344 alcohol-related crashes by Kentucky residents on Kentucky State roads were reported. The location of the crash and the home ZIP code from the driver's address were used to consider distance from home in the GIS. Analysis of the crash data revealed that a similar proportion of crashes in wet and dry counties are alcohol-related but that a higher proportion of dry counties residents are involved in an alcohol-related crash. However, when the distance from home variable is considered, several results suggest that dry county residents may be driving further when consuming alcohol. In part due to the rural nature of dry counties, drivers from dry counties have both alcohol-related and non-alcohol related crashes farther from their homes than residents from wet counties. Alcohol-related crashes by dry county residents in wet counties are the greatest average distance from home while crashes by wet county residents in wet counties are the smallest average distance. Drivers from dry counties over 21 years of age have alcohol-related crashes significantly farther from home than those under 21 who would not legally be admitted to drinking establishments in the wet counties. Furthermore, residents from dry counties that do not border wet counties have alcohol-related crashes on average farther from home than the border county residents. These last three results provide circumstantial evidence that some dry county drivers may be driving to wet counties to consume alcohol thus increasing impaired driving exposure. In conclusion, by considering crash location and driver residence, these findings indicate that county-level prohibition is not necessarily effective in improving highway safety.

  17. An evaluation of the physiological demands of elite rugby union using Global Positioning System tracking software.

    PubMed

    Cunniffe, Brian; Proctor, Wayne; Baker, Julien S; Davies, Bruce

    2009-07-01

    The current case study attempted to document the contemporary demands of elite rugby union. Players (n = 2) were tracked continuously during a competitive team selection game using Global Positioning System (GPS) software. Data revealed that players covered on average 6,953 m during play (83 minutes). Of this distance, 37% (2,800 m) was spent standing and walking, 27% (1,900 m) jogging, 10% (700 m) cruising, 14% (990 m) striding, 5% (320 m) high-intensity running, and 6% (420 m) sprinting. Greater running distances were observed for both players (6.7% back; 10% forward) in the second half of the game. Positional data revealed that the back performed a greater number of sprints (>20 km x h(-1)) than the forward (34 vs. 19) during the game. Conversely, the forward entered the lower speed zone (6-12 km x h(-1)) on a greater number of occasions than the back (315 vs. 229) but spent less time standing and walking (66.5 vs. 77.8%). Players were found to perform 87 moderate-intensity runs (>14 km x h(-1)) covering an average distance of 19.7 m (SD = 14.6). Average distances of 15.3 m (back) and 17.3 m (forward) were recorded for each sprint burst (>20 km x h(-1)), respectively. Players exercised at approximately 80 to 85% VO2max during the course of the game with a mean heart rate of 172 b x min(-1) ( approximately 88% HRmax). This corresponded to an estimated energy expenditure of 6.9 and 8.2 MJ, back and forward, respectively. The current study provides insight into the intense and physical nature of elite rugby using "on the field" assessment of physical exertion. Future use of this technology may help practitioners in design and implementation of individual position-specific training programs with appropriate management of player exercise load.

  18. Analysis of the choice of food products and the energy value of diets of female middle- and long-distance runners depending on the self-assessment of their nutritional habits

    PubMed

    Głąbska, Dominika; Jusińska, Marta

    2018-01-01

    Properly balanced diet is especially important in the case of young athletes, as it influences not only their physical development, but also influences results obtained during trainings and competitions. The aim of the study was to assess the choice of food products and the energy value of diets of female middleand long-distance runners, depending on the self-assessment of their nutritional habits. The study was conducted in the group of 40 female middle- and long-distance runners, aged 15-25, who declared average diet (n=15, 37.5%) or outstanding diet (n=25, 62.5%). Participants conducted three-day dietary record of the consumed dishes and drunk beverages, that was based on the self-reported data. The choice of products, the energy value of diets as well as macronutrients intake were compared depending on the self-assessment of the nutritional habits. Runners declaring outstanding diet were characterized by significantly lower intake of dairy beverages, than runners declaring average diet (p=0.0459), but simultaneously, by higher intake of mushrooms (p=0.0453). No difference of energy value of diets was stated between groups of runners depending on the self-assessment of their nutritional habits. Runners declaring outstanding diet were characterized by significantly lower intake of lactose, than runners declaring average diet (p=0.0119), but simultaneously, by higher intake of cholesterol (p=0.0307). The female middle- and long-distance runners analysed in the presented study do not assess the quality of their diet reliably, so they probably do not have the sufficient nutritional knowledge. There is a need to implement nutritional education among professional runners and their coaches, in order to improve the quality of diet of professional runners and, as a results maybe also to improve their sport results.

  19. Reinventing the wheel: comparison of two wheel cage styles for assessing mouse voluntary running activity.

    PubMed

    Seward, T; Harfmann, B D; Esser, K A; Schroder, E A

    2018-04-01

    Voluntary wheel cage assessment of mouse activity is commonly employed in exercise and behavioral research. Currently, no standardization for wheel cages exists resulting in an inability to compare results among data from different laboratories. The purpose of this study was to determine whether the distance run or average speed data differ depending on the use of two commonly used commercially available wheel cage systems. Two different wheel cages with structurally similar but functionally different wheels (electromechanical switch vs. magnetic switch) were compared side-by-side to measure wheel running data differences. Other variables, including enrichment and cage location, were also tested to assess potential impacts on the running wheel data. We found that cages with the electromechanical switch had greater inherent wheel resistance and consistently led to greater running distance per day and higher average running speed. Mice rapidly, within 1-2 days, adapted their running behavior to the type of experimental switch used, suggesting these running differences are more behavioral than due to intrinsic musculoskeletal, cardiovascular, or metabolic limits. The presence of enrichment or location of the cage had no detectable impact on voluntary wheel running. These results demonstrate that mice run differing amounts depending on the type of cage and switch mechanism used and thus investigators need to report wheel cage type/wheel resistance and use caution when interpreting distance/speed run across studies. NEW & NOTEWORTHY The results of this study highlight that mice will run different distances per day and average speed based on the inherent resistance present in the switch mechanism used to record data. Rapid changes in running behavior for the same mouse in the different cages demonstrate that a strong behavioral factor contributes to classic exercise outcomes in mice. Caution needs to be taken when interpreting mouse voluntary wheel running activity to include potential behavioral input and physiological parameters.

  20. Semiempirical Quantum Chemistry Model for the Lanthanides: RM1 (Recife Model 1) Parameters for Dysprosium, Holmium and Erbium

    PubMed Central

    Filho, Manoel A. M.; Dutra, José Diogo L.; Rocha, Gerd B.; Simas, Alfredo M.; Freire, Ricardo O.

    2014-01-01

    Complexes of dysprosium, holmium, and erbium find many applications as single-molecule magnets, as contrast agents for magnetic resonance imaging, as anti-cancer agents, in optical telecommunications, etc. Therefore, the development of tools that can be proven helpful to complex design is presently an active area of research. In this article, we advance a major improvement to the semiempirical description of lanthanide complexes: the Recife Model 1, RM1, model for the lanthanides, parameterized for the trications of Dy, Ho, and Er. By representing such lanthanide in the RM1 calculation as a three-electron atom with a set of 5 d, 6 s, and 6 p semiempirical orbitals, the accuracy of the previous sparkle models, mainly concentrated on lanthanide-oxygen and lanthanide-nitrogen distances, is extended to other types of bonds in the trication complexes’ coordination polyhedra, such as lanthanide-carbon, lanthanide-chlorine, etc. This is even more important as, for example, lanthanide-carbon atom distances in the coordination polyhedra of the complexes comprise about 30% of all distances for all complexes of Dy, Ho, and Er considered. Our results indicate that the average unsigned mean error for the lanthanide-carbon distances dropped from an average of 0.30 Å, for the sparkle models, to 0.04 Å for the RM1 model for the lanthanides; for a total of 509 such distances for the set of all Dy, Ho, and Er complexes considered. A similar behavior took place for the other distances as well, such as lanthanide-chlorine, lanthanide-bromine, lanthanide, phosphorus and lanthanide-sulfur. Thus, the RM1 model for the lanthanides, being advanced in this article, broadens the range of application of semiempirical models to lanthanide complexes by including comprehensively many other types of bonds not adequately described by the previous models. PMID:24497945

  1. Authorship Discovery in Blogs Using Bayesian Classification with Corrective Scaling

    DTIC Science & Technology

    2008-06-01

    4 2.3 W. Fucks ’ Diagram of n-Syllable Word Frequencies . . . . . . . . . . . . . . 5 3.1 Confusion Matrix for All Test Documents of 500...of the books which scholars believed he had. • Wilhelm Fucks discriminated between authors using the average number of syllables per word and average...distance between equal-syllabled words [8]. Fucks , too, concluded that a study such as his reveals a “possibility of a quantitative classification

  2. World citation and collaboration networks: uncovering the role of geography in science

    PubMed Central

    Pan, Raj Kumar; Kaski, Kimmo; Fortunato, Santo

    2012-01-01

    Modern information and communication technologies, especially the Internet, have diminished the role of spatial distances and territorial boundaries on the access and transmissibility of information. This has enabled scientists for closer collaboration and internationalization. Nevertheless, geography remains an important factor affecting the dynamics of science. Here we present a systematic analysis of citation and collaboration networks between cities and countries, by assigning papers to the geographic locations of their authors’ affiliations. The citation flows as well as the collaboration strengths between cities decrease with the distance between them and follow gravity laws. In addition, the total research impact of a country grows linearly with the amount of national funding for research & development. However, the average impact reveals a peculiar threshold effect: the scientific output of a country may reach an impact larger than the world average only if the country invests more than about 100,000 USD per researcher annually. PMID:23198092

  3. Hydrogen bonds in concreto and in computro

    NASA Astrophysics Data System (ADS)

    Stouten, Pieter F. W.; Kroon, Jan

    1988-07-01

    Molecular dynamics simulations of liquid water and liquid methanol have been carried out. For both liquids an effective pair potential was used. The models were fitted to the heat of vaporization, pressure and various radial distribution functions resulting from diffraction experiments on liquids. In both simulations 216 molecules were put in a cubic periodical ☐. The system was loosely coupled to a temperature bath and to a pressure bath. Following an initial equilibration period relevant data were sampled during 15 ps. The distributions of oxygen—oxygen distances in hydrogen bonds obtained from the two simulations are essentially the same. The distribution obtained from crystal data is somewhat different: the maximum has about the same position, but the curve is much narrower, which can be expected merely from the fact that diffraction experiments only supply average atomic positions and hence average interatomic distances. When thermal motion is taken into account a closer likeness is observed.

  4. World citation and collaboration networks: uncovering the role of geography in science

    NASA Astrophysics Data System (ADS)

    Pan, Raj Kumar; Kaski, Kimmo; Fortunato, Santo

    2012-11-01

    Modern information and communication technologies, especially the Internet, have diminished the role of spatial distances and territorial boundaries on the access and transmissibility of information. This has enabled scientists for closer collaboration and internationalization. Nevertheless, geography remains an important factor affecting the dynamics of science. Here we present a systematic analysis of citation and collaboration networks between cities and countries, by assigning papers to the geographic locations of their authors' affiliations. The citation flows as well as the collaboration strengths between cities decrease with the distance between them and follow gravity laws. In addition, the total research impact of a country grows linearly with the amount of national funding for research & development. However, the average impact reveals a peculiar threshold effect: the scientific output of a country may reach an impact larger than the world average only if the country invests more than about 100,000 USD per researcher annually.

  5. Optical properties of ion beam textured metals. [using copper, silicon, aluminum, titanium and stainless steels

    NASA Technical Reports Server (NTRS)

    Hudson, W. R.; Weigand, A. J.; Mirtich, M. J.

    1977-01-01

    Copper, silicon, aluminum, titanium and 316 stainless steel were textured by 1000 eV xenon ions from an 8 cm diameter electron bombardment ion source. Simultaneously sputter-deposited tantalum was used to facilitate the development of the surface microstructure. Scanning electron microscopy of the ion textured surfaces revealed two types of microstructure. Copper, silicon, and aluminum developed a cone structure with an average peak-to-peak distance ranging from 1 micron for silicon to 6 microns for aluminum. Titanium and 316 stainless steel developed a serpentine ridge structure. The average peak-to-peak distance for both of these materials was 0.5 micron. Spectral reflectance was measured using an integrating sphere and a holraum reflectometer. Total reflectance for air mass 0 and 2, solar absorptance and total emittance normalized for a 425 K black body were calculated from the reflectance measurements.

  6. Scanning the pressure-induced distortion of fingerprints.

    PubMed

    Mil'shtein, S; Doshi, U

    2004-01-01

    Fingerprint recognition technology is an important part of criminal investigations it is the basis of some security systems and an important tool of government operations such as the Immigration and Naturalization Services, registration procedures in the Armed Forces, and so forth. After the tragic events of September 11, 2001, the importance of reliable fingerprint recognition technology became even more obvious. In the current study, pressure-induced changes of distances between ridges of a fingerprint were measured. Using calibrated silicon pressure sensors we scanned the distribution of pressure across a finger pixel by pixel, and also generated maps of an average pressure distribution during fingerprinting. Emulating the fingerprinting procedure employed with widely used optical scanners, we found that on average the distance between ridges decreases by about 20% when a finger is positioned on a scanner. Controlled loading of a finger demonstrated that it is impossible to reproduce the same distribution of pressure across a given finger during repeated fingerprinting procedures.

  7. [Identification of common medicinal snakes in medicated liquor of Guangdong by COI barcode sequence].

    PubMed

    Liao, Jing; Chao, Zhi; Zhang, Liang

    2013-11-01

    To identify the common snakes in medicated liquor of Guangdong using COI barcode sequence,and to test the feasibility. The COI barcode sequences of collected medicinal snakes were amplified and sequenced. The sequences combined with the data from GenBank were analyzed for divergence and building a neighbor-joining(NJ) tree with MEGA 5.0. The genetic distance and NJ tree demonstrated that there were 241 variable sites in these species, and the average (A + T) content of 56.2% was higher than the average (G + C) content of 43.7%. The maximum interspecific genetic distance was 0.2568, and the minimum was 0. 1519. In the NJ tree,each species formed a monophyletic clade with bootstrap supports of 100%. DNA barcoding identification method based on the COI sequence is accurate and can be applied to identify the common medicinal snakes.

  8. End-to-end distance and contour length distribution functions of DNA helices

    NASA Astrophysics Data System (ADS)

    Zoli, Marco

    2018-06-01

    I present a computational method to evaluate the end-to-end and the contour length distribution functions of short DNA molecules described by a mesoscopic Hamiltonian. The method generates a large statistical ensemble of possible configurations for each dimer in the sequence, selects the global equilibrium twist conformation for the molecule, and determines the average base pair distances along the molecule backbone. Integrating over the base pair radial and angular fluctuations, I derive the room temperature distribution functions as a function of the sequence length. The obtained values for the most probable end-to-end distance and contour length distance, providing a measure of the global molecule size, are used to examine the DNA flexibility at short length scales. It is found that, also in molecules with less than ˜60 base pairs, coiled configurations maintain a large statistical weight and, consistently, the persistence lengths may be much smaller than in kilo-base DNA.

  9. Molecular phylogenetic trees - On the validity of the Goodman-Moore augmentation algorithm

    NASA Technical Reports Server (NTRS)

    Holmquist, R.

    1979-01-01

    A response is made to the reply of Nei and Tateno (1979) to the letter of Holmquist (1978) supporting the validity of the augmentation algorithm of Moore (1977) in reconstructions of nucleotide substitutions by means of the maximum parsimony principle. It is argued that the overestimation of the augmented numbers of nucleotide substitutions (augmented distances) found by Tateno and Nei (1978) is due to an unrepresentative data sample and that it is only necessary that evolution be stochastically uniform in different regions of the phylogenetic network for the augmentation method to be useful. The importance of the average value of the true distance over all links is explained, and the relative variances of the true and augmented distances are calculated to be almost identical. The effects of topological changes in the phylogenetic tree on the augmented distance and the question of the correctness of ancestral sequences inferred by the method of parsimony are also clarified.

  10. Error Estimation for the Linearized Auto-Localization Algorithm

    PubMed Central

    Guevara, Jorge; Jiménez, Antonio R.; Prieto, Jose Carlos; Seco, Fernando

    2012-01-01

    The Linearized Auto-Localization (LAL) algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs), using only the distance measurements to a mobile node whose position is also unknown. The LAL algorithm calculates the inter-beacon distances, used for the estimation of the beacons’ positions, from the linearized trilateration equations. In this paper we propose a method to estimate the propagation of the errors of the inter-beacon distances obtained with the LAL algorithm, based on a first order Taylor approximation of the equations. Since the method depends on such approximation, a confidence parameter τ is defined to measure the reliability of the estimated error. Field evaluations showed that by applying this information to an improved weighted-based auto-localization algorithm (WLAL), the standard deviation of the inter-beacon distances can be improved by more than 30% on average with respect to the original LAL method. PMID:22736965

  11. [Genetic relationship analysis of Ephedra intermedia from different habitat in Gansu by ISSR analysis].

    PubMed

    Zhu, Tian-Tian; Jin, Ling; Du, Tao; Cui, Zhi-Jia; Zhang, Xian-Fei; Wu, Di

    2013-09-01

    To investigate the genetic relationship of Ephedra intermedia from different habitats in Gansu. The genetic diversity and genetic relationship of E. intermedia from different habitats in Gansu were studied by ISSR molecular marker technique. Twelve ISSR primers were selected from 70 ISSR primers and used for ISSR amplification. Total 112 loci were amplified, in which 81 were polymorphic loci, the average percentage of polymorphie bands (PPB) was 72.32%. Clustering results indicated that the wild species and cultivating species were clustered into different group. The wild species, which had closer distance, were clustered into a group. E. intermedia of different habitats in Gansu have rich genetic diversities among species, it is the reason that E. intermedia has strong adaptability and wide distribution. Further, the genetic distance of E. intermedia is associated with geographical distance, the further distance can hinder the gene flow.

  12. The heterophoria of 3-5 year old children as a function of viewing distance and target type.

    PubMed

    Troyer, Mary E; Sreenivasan, Vidhyapriya; Peper, T J; Candy, T Rowan

    2017-01-01

    Heterophoria is the misalignment of the eyes in monocular viewing and represents the accuracy of vergence driven by all classical cues except disparity. It is challenging to assess restless children using clinical cover tests, and phoria in early childhood is poorly understood. Here we used eye tracking to assess phoria as a function of viewing distance and target in adults and young children, with comparison to clinical cover tests. Purkinje image tracking (MCS PowerRefractor) was used to record eye alignment in adults (19-28 years, N = 24) and typically developing children (3-5 years, N = 24). Objective unilateral and alternating cover tests were performed using an infrared filter while participants viewed a pseudo-randomised sequence of Lea symbols (0.18 logMAR; Snellen: 20/30 or 6/9) and animated cartoon movies at distances of 40 cm, 1 m, and 6 m. For the unilateral cover test, a 10 s binocular period preceded and followed 30 s of occlusion of the right eye. For the alternating cover test, a 10 s binocular period preceded and followed alternate covering of right and left eyes for 3-s each. Phoria was derived from the difference in weighted average binocular and monocular alignment. A masked prism-neutralised clinical cover test was performed for each of the conditions for comparison. Closer viewing distance resulted in greater exophoria for both children and adults (p < 0.001). Phorias were similar for adults and children for each viewing distance and target, with mean differences of less than 2 prism dioptres (pd). Overall, the average PowerRefractor phorias (pooled across protocols) for adults were 1.3, 2.3 and 3.8 pd exophoria and for children were 0.1 pd esophoria, 0.94 and 3.8 pd exophoria for the 6 m, 1 m and 40 cm distances respectively. The corresponding clinical cover test values were 0.7, 1.9, and 4.1 pd exophoria for adults and 0, 1.5 and 3.3 pd exophoria for the children. Refractive states were also similar (≤0.5 D difference) for viewing the Lea symbols or movie for any protocol tested. Phoria estimation can be challenging for a pre-school child. These data suggest that by 3-5 years of age objective eye-tracking measures in a typically developing group are adult-like at the range of distances tested, and that use of an animated movie produces similar average results to a small optotype (0.18 logMAR; Snellen 20/30 or 6/9). © 2016 The Authors Ophthalmic & Physiological Optics © 2016 The College of Optometrists.

  13. The accuracy of assessment of walking distance in the elective spinal outpatients setting.

    PubMed

    Okoro, Tosan; Qureshi, Assad; Sell, Beulah; Sell, Philip

    2010-02-01

    Self reported walking distance is a clinically relevant measure of function. The aim of this study was to define patient accuracy and understand factors that might influence perceived walking distance in an elective spinal outpatients setting. A prospective cohort study. 103 patients were asked to perform one test of distance estimation and 2 tests of functional distance perception using pre-measured landmarks. Standard spine specific outcomes included the patient reported claudication distance, Oswestry disability index (ODI), Low Back Outcome Score (LBOS), visual analogue score (VAS) for leg and back, and other measures. There are over-estimators and under-estimators. Overall, the accuracy to within 9.14 metres (m) (10 yards) was poor at only 5% for distance estimation and 40% for the two tests of functional distance perception. Distance: Actual distance 111 m; mean response 245 m (95% CI 176.3-314.7), Functional test 1 actual distance 29.2 m; mean response 71.7 m (95% CI 53.6-88.9) Functional test 2 actual distance 19.6 m; mean response 47.4 m (95% CI 35.02-59.95). Surprisingly patients over 60 years of age (n = 43) are twice as accurate with each test performed compared to those under 60 (n = 60) (average 70% overestimation compared to 140%; p = 0.06). Patients in social class I (n = 18) were more accurate than those in classes II-V (n = 85): There was a positive correlation between poor accuracy and increasing MZD (Pearson's correlation coefficient 0.250; p = 0.012). ODI, LBOS and other parameters measured showed no correlation. Subjective distance perception and estimation is poor in this population. Patients over 60 and those with a professional background are more accurate but still poor.

  14. The enhancement model of ICT competence for the teachers of SMP Terbuka in Central Java to support long distance learning program

    NASA Astrophysics Data System (ADS)

    Widowati, Trisnani; Purwanti, Dwi

    2017-03-01

    ICT-based learning for SMP Terbuka is a manifestation of the first pillar of DEPDIKNAS Strategic Plan 2005-2009, about the use of ICT as the facility of long distance learning. By implementing ICT-based learning, the communication between the teacher and the students is possible to happen although both parties are in differnet places. The problem in implementing ICT-based learning for SMP Terbuka is the low competence of the teachers in ICT mastery, because this research is aimed to formulate the enhancement model of ICT competence for the teachers of SMP Terbuka in Central Java to support long distance learning program. This research shows that Supervised-Teachers and Tutor Teachers Competence in ICT is still low with the average of Supervised-Teachers competence in operating Ms.Word application of 59.6%, Ms.Excel 55.40%, Power Point 43.40% and internet mastery of 41.8%; while the competence of Tutor Teachers is lower with the average of 40.40% in operating Ms. Word, 35.20% in Ms.Excel, 28.00% in Power Point, and 29% in internet mastery. It means that Supervised-Teachers understand ICT, but they do not master it; while Tutor Teachers have just understood ICT and have a low mastery in Ms.Word. The output of this research is: The new findings of the enhancement model of ICT competence for the teachers of SMP Terbuka in Central Java to support long distance learning program.

  15. Indirect estimates of natal dispersal distance from genetic data in a stream-dwelling fish (Mogurnda adspersa).

    PubMed

    Shipham, Ashlee; Schmidt, Daniel J; Hughes, Jane M

    2013-01-01

    Recent work has highlighted the need to account for hierarchical patterns of genetic structure when estimating evolutionary and ecological parameters of interest. This caution is particularly relevant to studies of riverine organisms, where hierarchical structure appears to be commonplace. Here, we indirectly estimate dispersal distance in a hierarchically structured freshwater fish, Mogurnda adspersa. Microsatellite and mitochondrial DNA (mtDNA) data were obtained for 443 individuals across 27 sites separated by an average of 1.3 km within creeks of southeastern Queensland, Australia. Significant genetic structure was found among sites (mtDNA Φ(ST) = 0.508; microsatellite F(ST) = 0.225, F'(ST) = 0.340). Various clustering methods produced congruent patterns of hierarchical structure reflecting stream architecture. Partial mantel tests identified contiguous sets of sample sites where isolation by distance (IBD) explained F(ST) variation without significant contribution of hierarchical structure. Analysis of mean natal dispersal distance (σ) within sets of IBD-linked sample sites suggested most dispersal occurs over less than 1 km, and the average effective density (D(e)) was estimated at 11.5 individuals km(-1); indicating sedentary behavior and small effective population size are responsible for the remarkable patterns of genetic structure observed. Our results demonstrate that Rousset's regression-based method is applicable to estimating the scale of dispersal in riverine organisms and that identifying contiguous populations that satisfy the assumptions of this model is achievable with genetic clustering methods and partial correlations.

  16. A Proposal for Automatic Fruit Harvesting by Combining a Low Cost Stereovision Camera and a Robotic Arm

    PubMed Central

    Font, Davinia; Pallejà, Tomàs; Tresanchez, Marcel; Runcan, David; Moreno, Javier; Martínez, Dani; Teixidó, Mercè; Palacín, Jordi

    2014-01-01

    This paper proposes the development of an automatic fruit harvesting system by combining a low cost stereovision camera and a robotic arm placed in the gripper tool. The stereovision camera is used to estimate the size, distance and position of the fruits whereas the robotic arm is used to mechanically pickup the fruits. The low cost stereovision system has been tested in laboratory conditions with a reference small object, an apple and a pear at 10 different intermediate distances from the camera. The average distance error was from 4% to 5%, and the average diameter error was up to 30% in the case of a small object and in a range from 2% to 6% in the case of a pear and an apple. The stereovision system has been attached to the gripper tool in order to obtain relative distance, orientation and size of the fruit. The harvesting stage requires the initial fruit location, the computation of the inverse kinematics of the robotic arm in order to place the gripper tool in front of the fruit, and a final pickup approach by iteratively adjusting the vertical and horizontal position of the gripper tool in a closed visual loop. The complete system has been tested in controlled laboratory conditions with uniform illumination applied to the fruits. As a future work, this system will be tested and improved in conventional outdoor farming conditions. PMID:24984059

  17. A proposal for automatic fruit harvesting by combining a low cost stereovision camera and a robotic arm.

    PubMed

    Font, Davinia; Pallejà, Tomàs; Tresanchez, Marcel; Runcan, David; Moreno, Javier; Martínez, Dani; Teixidó, Mercè; Palacín, Jordi

    2014-06-30

    This paper proposes the development of an automatic fruit harvesting system by combining a low cost stereovision camera and a robotic arm placed in the gripper tool. The stereovision camera is used to estimate the size, distance and position of the fruits whereas the robotic arm is used to mechanically pickup the fruits. The low cost stereovision system has been tested in laboratory conditions with a reference small object, an apple and a pear at 10 different intermediate distances from the camera. The average distance error was from 4% to 5%, and the average diameter error was up to 30% in the case of a small object and in a range from 2% to 6% in the case of a pear and an apple. The stereovision system has been attached to the gripper tool in order to obtain relative distance, orientation and size of the fruit. The harvesting stage requires the initial fruit location, the computation of the inverse kinematics of the robotic arm in order to place the gripper tool in front of the fruit, and a final pickup approach by iteratively adjusting the vertical and horizontal position of the gripper tool in a closed visual loop. The complete system has been tested in controlled laboratory conditions with uniform illumination applied to the fruits. As a future work, this system will be tested and improved in conventional outdoor farming conditions.

  18. An iterative method for the localization of a neutron source in a large box (container)

    NASA Astrophysics Data System (ADS)

    Dubinski, S.; Presler, O.; Alfassi, Z. B.

    2007-12-01

    The localization of an unknown neutron source in a bulky box was studied. This can be used for the inspection of cargo, to prevent the smuggling of neutron and α emitters. It is important to localize the source from the outside for safety reasons. Source localization is necessary in order to determine its activity. A previous study showed that, by using six detectors, three on each parallel face of the box (460×420×200 mm 3), the location of the source can be found with an average distance of 4.73 cm between the real source position and the calculated one and a maximal distance of about 9 cm. Accuracy was improved in this work by applying an iteration method based on four fixed detectors and the successive iteration of positioning of an external calibrating source. The initial positioning of the calibrating source is the plane of detectors 1 and 2. This method finds the unknown source location with an average distance of 0.78 cm between the real source position and the calculated one and a maximum distance of 3.66 cm for the same box. For larger boxes, localization without iterations requires an increase in the number of detectors, while localization with iterations requires only an increase in the number of iteration steps. In addition to source localization, two methods for determining the activity of the unknown source were also studied.

  19. The Impact of Proposed Changes in Liver Allocation Policy on Cold Ischemia Times and Organ Transportation Costs

    PubMed Central

    DuBay, D. A.; MacLennan, P. A.; Reed, R. D.; Fouad, M.; Martin, M.; Meeks, C. B.; Taylor, G.; Kilgore, M. L.; Tankersley, M.; Gray, S. H.; White, J. A.; Eckhoff, D. E.; Locke, J. E.

    2015-01-01

    Changes to the liver allocation system have been proposed to decrease regional variation in access to liver transplant. It is unclear what impact these changes will have on cold ischemia times (CITs) and donor transportation costs. Therefore, we performed a retrospective single center study (2008–2012) measuring liver procurement CIT and transportation costs. Four groups were defined: Local-within driving distance (Local-D, n = 262), Local-flight (Local-F, n = 105), Regional-flight <3 h (Regional <3h, n = 61) and Regional-Flight >3 h (Regional >3h, n = 53). The median travel distance increased in each group, varying from zero miles (Local-D), 196 miles (Local-F), 384 miles (Regional <3 h), to 1647 miles (Regional >3 h). Increasing travel distances did not significantly increase CIT until the flight time was >3 h. The average CIT ranged from 5.0 to 6.0 h for Local-D, Local-F and Regional <3h, but increased to 10 h for Regional >3h (p < 0.0001). Transportation costs increased with greater distance traveled: Local-D $101, Local-F $1993, Regional <3h $8324 and Regional >3 h $27 810 (p < 0.0001). With proposed redistricting, local financial modeling suggests that the average liver donor procurement transportation variable direct costs will increase from $2415 to $7547/liver donor, an increase of 313%. These findings suggest that further discussion among transplant centers and insurance providers is needed prior to policy implementation. PMID:25612501

  20. Nb K-edge x-ray absorption investigation of the pressure induced amorphization in A-site deficient double perovskite La1/3NbO3.

    PubMed

    Marini, C; Noked, O; Kantor, I; Joseph, B; Mathon, O; Shuker, R; Kennedy, B J; Pascarelli, S; Sterer, E

    2016-02-03

    Nb K-edge x-ray absorption spectroscopy is utilized to investigate the changes in the local structure of the A-site deficient double perovskite La1/3NbO3 which undergoes a pressure induced irreversible amorphization. EXAFS results show that with increasing pressure up to 7.5 GPa, the average Nb-O bond distance decreases in agreement with the expected compression and tilting of the NbO6 octahedra. On the contrary, above 7.5 GPa, the average Nb-O bond distance show a tendency to increase. Significant changes in the Nb K-edge XANES spectrum with evident low energy shift of the pre-peak and the absorption edge is found to happen in La1/3NbO3 above 6.3 GPa. These changes evidence a gradual reduction of the Nb cations from Nb(5+) towards Nb(4+) above 6.3 GPa. Such a valence change accompanied by the elongation of the average Nb-O bond distances in the octahedra, introduces repulsion forces between non-bonding adjacent oxygen anions in the unoccupied A-sites. Above a critical pressure, the Nb reduction mechanism can no longer be sustained by the changing local structure and amorphization occurs, apparently due to the build-up of local strain. EXAFS and XANES results indicate two distinct pressure regimes having different local and electronic response in the La1/3NbO3 system before the occurence of the pressure induced amorphization at  ∼14.5 GPa.

  1. The Lateral Decubitus Breast Boost: Description, Rationale, and Efficacy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ludwig, Michelle S., E-mail: mludwig@mdanderson.or; McNeese, Marsha D.; Buchholz, Thomas A.

    2010-01-15

    Purpose: To describe and evaluate the modified lateral decubitus boost, a breast irradiation technique. Patients are repositioned and resimulated for electron boost to minimize the necessary depth for the electron beam and optimize target volume coverage. Methods and Materials: A total of 2,606 patients were treated with post-lumpectomy radiation at our institution between January 1, 2000, and February 1, 2008. Of these, 231 patients underwent resimulation in the lateral decubitus position with electron boost. Distance from skin to the maximal depth of target volume was measured in both the original and boost plans. Age, body mass index (BMI), boost electronmore » energy, and skin reaction were evaluated. Results: Resimulation in the lateral decubitus position reduced the distance from skin to maximal target volume depth in all patients. Average depth reduction by repositioning was 2.12 cm, allowing for an average electron energy reduction of approximately 7 MeV. Mean skin entrance dose was reduced from about 90% to about 85% (p < 0.001). Only 14 patients (6%) experienced moist desquamation in the boost field at the end of treatment. Average BMI of these patients was 30.4 (range, 17.8-50.7). BMI greater than 30 was associated with more depth reduction by repositioning and increased risk of moist desquamation. Conclusions: The lateral decubitus position allows for a decrease in the distance from the skin to the target volume depth, improving electron coverage of the tumor bed while reducing skin entrance dose. This is a well-tolerated regimen for a patient population with a high BMI or deep tumor location.« less

  2. Extensive dispersal of Roanoke logperch (Percina rex) inferred from genetic marker data

    USGS Publications Warehouse

    Roberts, James H.; Angermeier, Paul; Hallerman, Eric M.

    2016-01-01

    The dispersal ecology of most stream fishes is poorly characterised, complicating conservation efforts for these species. We used microsatellite DNA marker data to characterise dispersal patterns and effective population size (Ne) for a population of Roanoke logperchPercina rex, an endangered darter (Percidae). Juveniles and candidate parents were sampled for 2 years at sites throughout the Roanoke River watershed. Dispersal was inferred via genetic assignment tests (ATs), pedigree reconstruction (PR) and estimation of lifetime dispersal distance under a genetic isolation-by-distance model. Estimates of Ne varied from 105 to 1218 individuals, depending on the estimation method. Based on PR, polygamy was frequent in parents of both sexes, with individuals spawning with an average of 2.4 mates. The sample contained 61 half-sibling pairs, but only one parent–offspring pair and no full-sib pairs, which limited our ability to discriminate natal dispersal of juveniles from breeding dispersal of their parents between spawning events. Nonetheless, all methods indicated extensive dispersal. The AT indicated unrestricted dispersal among sites ≤15 km apart, while siblings inferred by the PR were captured an average of 14 km and up to 55 km apart. Model-based estimates of median lifetime dispersal distance (6–24 km, depending on assumptions) bracketed AT and PR estimates, indicating that widely dispersed individuals do, on average, contribute to gene flow. Extensive dispersal of P. rex suggests that darters and other small benthic stream fishes may be unexpectedly mobile. Monitoring and management activities for such populations should encompass entire watersheds to fully capture population dynamics.

  3. Growth Oscillatory Zoning in Erythrite, Ideally Co3(AsO4)2·8H2O: Structural Variations in Vivianite-Group Minerals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antao, Sytle M.; Dhaliwal, Inayat

    The crystal structure of an oscillatory zoned erythrite sample from Aghbar mine, Bou Azzer, Morocco, was refined using synchrotron high-resolution powder X-ray diffraction (HRPXRD) data, Rietveld refinement, space group C2/m, and Z = 2. The crystal contains two sets of oscillatory zones that appear to have developed during epitaxial growth. The unit-cell parameters obtained are a = 10.24799(3) Å, b = 13.42490(7) Å, c = 4.755885(8) Å, β = 105.1116(3)°, and V = 631.680(4) Å3. The empirical formula for erythrite, obtained with electron-probe micro-analysis (EPMA), is [Co2.78Zn0.11Ni0.07Fe0.04]Σ3.00(AsO4)2·8H2O. Erythrite belongs to the vivianite-type structure that contains M1O2(H2O)4 octahedra and M22O6(H2O)4 octahedralmore » dimers that are linked by TO4 (T5+ = As or P) tetrahedra to form complex layers parallel to the (010) plane. These layers are connected by hydrogen bonds. The average [6] = 2.122(1) Å and average [6] = 2.088(1) Å. With space group C2/m, there are two solid solutions: M3(AsO4)2·8H2O and M3(PO4)2·8H2O where M2+ = Mg, Fe, Co, Ni, or Zn. In these As- and P-series, using data from this study and from the literature, we find that their structural parameters evolve linearly with V and in a nearly parallel manner despite of the large difference in size between P5+ (0.170 Å) and As5+ (0.355 Å) cations. Average [4], [6], and [6] distances increase linearly with V. The average distance is affected by M atoms, whereas the average distance is unaffected because it contains shorter and stronger P–O bonds. Although As- and P-series occur naturally, there is no structural reason why similar V-series vivianite-group minerals do not occur naturally or cannot be synthesized.« less

  4. Absolute distance measurement by dual-comb interferometry with multi-channel digital lock-in phase detection

    NASA Astrophysics Data System (ADS)

    Yang, Ruitao; Pollinger, Florian; Meiners-Hagen, Karl; Krystek, Michael; Tan, Jiubin; Bosse, Harald

    2015-08-01

    We present a dual-comb-based heterodyne multi-wavelength absolute interferometer capable of long distance measurements. The phase information of the various comb modes is extracted in parallel by a multi-channel digital lock-in phase detection scheme. Several synthetic wavelengths of the same order are constructed and the corresponding phases are averaged to deduce the absolute lengths with significantly reduced uncertainty. Comparison experiments with an incremental HeNe reference interferometer show a combined relative measurement uncertainty of 5.3 × 10-7 at a measurement distance of 20 m. Combining the advantage of synthetic wavelength interferometry and dual-comb interferometry, our compact and simple approach provides sufficient precision for many industrial applications.

  5. Nipple placement in simple mastectomy with free nipple grafting for severe gynecomastia.

    PubMed

    Murphy, T P; Ehrlichman, R J; Seckel, B R

    1994-11-01

    Severe gynecomastia with excessive skin is difficult to treat by only periareolar excision or suction-assisted lipectomy or both. In these patients, total mastectomy and free nipple grafting may be the best option. Placement of the nipple, however, has been arbitrary. With use of 20 "aesthetically perfect" men as models, standard nipple distances were identified. The average sternal notch-to-nipple measurement was 21 cm. In addition, two consistent ratios were identified. The nipple plane was located 0.33 times the distance from the sternal notch to the pubis, and the internipple distance was 0.23 times the chest circumference. With use of preoperatively obtained measurements of the sternal notch to pubis and chest circumference, accurate nipple placement can be accomplished.

  6. A new statistical distance scale for planetary nebulae

    NASA Astrophysics Data System (ADS)

    Ali, Alaa; Ismail, H. A.; Alsolami, Z.

    2015-05-01

    In the first part of the present article we discuss the consistency among different individual distance methods of Galactic planetary nebulae, while in the second part we develop a new statistical distance scale based on a calibrating sample of well determined distances. A set composed of 315 planetary nebulae with individual distances are extracted from the literature. Inspecting the data set indicates that the accuracy of distances is varying among different individual methods and also among different sources where the same individual method was applied. Therefore, we derive a reliable weighted mean distance for each object by considering the influence of the distance error and the weight of each individual method. The results reveal that the discussed individual methods are consistent with each other, except the gravity method that produces higher distances compared to other individual methods. From the initial data set, we construct a standard calibrating sample consists of 82 objects. This sample is restricted only to the objects with distances determined from at least two different individual methods, except few objects with trusted distances determined from the trigonometric, spectroscopic, and cluster membership methods. In addition to the well determined distances for this sample, it shows a lot of advantages over that used in the prior distance scales. This sample is used to recalibrate the mass-radius and radio surface brightness temperature-radius relationships. An average error of ˜30 % is estimated for the new distance scale. The newly distance scale is compared with the most widely used statistical scales in literature, where the results show that it is roughly similar to the majority of them within ˜±20 % difference. Furthermore, the new scale yields a weighted mean distance to the Galactic center of 7.6±1.35 kpc, which in good agreement with the very recent measure of Malkin 2013.

  7. Shifting Sand in Herschel Crater

    NASA Image and Video Library

    2011-11-17

    The eastern margin of a rippled dune in Herschel Crater on Mars moved an average distance of three meters about three yards between March 3, 2007 and December 1, 2010, in one of two images taken by NASA Mars Reconnaissance Orbiter.

  8. Evaluation of Traffic Density Parameters as an Indicator of Vehicle Emission-Related Near-Road Air Pollution: A Case Study with NEXUS Measurement Data on Black Carbon.

    PubMed

    Liu, Shi V; Chen, Fu-Lin; Xue, Jianping

    2017-12-15

    An important factor in evaluating health risk of near-road air pollution is to accurately estimate the traffic-related vehicle emission of air pollutants. Inclusion of traffic parameters such as road length/area, distance to roads, and traffic volume/intensity into models such as land use regression (LUR) models has improved exposure estimation. To better understand the relationship between vehicle emissions and near-road air pollution, we evaluated three traffic density-based indices: Major-Road Density (MRD), All-Traffic Density (ATD) and Heavy-Traffic Density (HTD) which represent the proportions of major roads, major road with annual average daily traffic (AADT), and major road with commercial annual average daily traffic (CAADT) in a buffered area, respectively. We evaluated the potential of these indices as vehicle emission-specific near-road air pollutant indicators by analyzing their correlation with black carbon (BC), a marker for mobile source air pollutants, using measurement data obtained from the Near-road Exposures and Effects of Urban Air Pollutants Study (NEXUS). The average BC concentrations during a day showed variations consistent with changes in traffic volume which were classified into high, medium, and low for the morning rush hours, the evening rush hours, and the rest of the day, respectively. The average correlation coefficients between BC concentrations and MRD, ATD, and HTD, were 0.26, 0.18, and 0.48, respectively, as compared with -0.31 and 0.25 for two commonly used traffic indicators: nearest distance to a major road and total length of the major road. HTD, which includes only heavy-duty diesel vehicles in its traffic count, gives statistically significant correlation coefficients for all near-road distances (50, 100, 150, 200, 250, and 300 m) that were analyzed. Generalized linear model (GLM) analyses show that season, traffic volume, HTD, and distance from major roads are highly related to BC measurements. Our analyses indicate that traffic density parameters may be more specific indicators of near-road BC concentrations for health risk studies. HTD is the best index for reflecting near-road BC concentrations which are influenced mainly by the emissions of heavy-duty diesel engines.

  9. Evaluation of Traffic Density Parameters as an Indicator of Vehicle Emission-Related Near-Road Air Pollution: A Case Study with NEXUS Measurement Data on Black Carbon

    PubMed Central

    Chen, Fu-Lin; Xue, Jianping

    2017-01-01

    An important factor in evaluating health risk of near-road air pollution is to accurately estimate the traffic-related vehicle emission of air pollutants. Inclusion of traffic parameters such as road length/area, distance to roads, and traffic volume/intensity into models such as land use regression (LUR) models has improved exposure estimation. To better understand the relationship between vehicle emissions and near-road air pollution, we evaluated three traffic density-based indices: Major-Road Density (MRD), All-Traffic Density (ATD) and Heavy-Traffic Density (HTD) which represent the proportions of major roads, major road with annual average daily traffic (AADT), and major road with commercial annual average daily traffic (CAADT) in a buffered area, respectively. We evaluated the potential of these indices as vehicle emission-specific near-road air pollutant indicators by analyzing their correlation with black carbon (BC), a marker for mobile source air pollutants, using measurement data obtained from the Near-road Exposures and Effects of Urban Air Pollutants Study (NEXUS). The average BC concentrations during a day showed variations consistent with changes in traffic volume which were classified into high, medium, and low for the morning rush hours, the evening rush hours, and the rest of the day, respectively. The average correlation coefficients between BC concentrations and MRD, ATD, and HTD, were 0.26, 0.18, and 0.48, respectively, as compared with −0.31 and 0.25 for two commonly used traffic indicators: nearest distance to a major road and total length of the major road. HTD, which includes only heavy-duty diesel vehicles in its traffic count, gives statistically significant correlation coefficients for all near-road distances (50, 100, 150, 200, 250, and 300 m) that were analyzed. Generalized linear model (GLM) analyses show that season, traffic volume, HTD, and distance from major roads are highly related to BC measurements. Our analyses indicate that traffic density parameters may be more specific indicators of near-road BC concentrations for health risk studies. HTD is the best index for reflecting near-road BC concentrations which are influenced mainly by the emissions of heavy-duty diesel engines. PMID:29244754

  10. Lineages with long durations are old and morphologically average: an analysis using multiple datasets.

    PubMed

    Liow, Lee Hsiang

    2007-04-01

    Lineage persistence is as central to biology as evolutionary change. Important questions regarding persistence include: why do some lineages outlive their relatives, neither becoming extinct nor evolving into separate lineages? Do these long-duration lineages have distinctive ecological or morphological traits that correlate with their geologic durations and potentially aid their survival? In this paper, I test the hypothesis that lineages (species and higher taxa) with longer geologic durations have morphologies that are more average than expected by chance alone. I evaluate this hypothesis for both individual lineages with longer durations and groups of lineages with longer durations, using more than 60 published datasets of animals with adequate fossil records. Analyses presented here show that groups of lineages with longer durations fall empirically into one of three theoretically possible scenarios, namely: (1) the morphology of groups of longer duration lineages is closer to the grand average of their inclusive group, that is, their relative morphological distance is smaller than expected by chance alone, when compared with rarified samples of their shorter duration relatives (a negative group morpho-duration distribution); (2) the relative morphological distance of groups of longer duration lineages is no different from rarified samples of their shorter duration relatives (a null group morpho-duration distribution); and (3) the relative morphological distance of groups of longer duration lineages is greater than expected when compared with rarified samples of their shorter duration relatives (a positive group morpho-duration distribution). Datasets exhibiting negative group morpho-duration distributions predominate. However, lineages with higher ranks in the Linnean hierarchy demonstrate positive morpho-duration distributions more frequently. The relative morphological distance of individual longer duration lineages is no different from that of rarified samples of their shorter duration relatives (a null individual morpho-duration distribution) for the majority of datasets studied. Contrary to the common idea that very persistent lineages are special or unique in some significant way, both the results from analyses of long-duration lineages as groups and individuals show that they are morphologically average. Persistent lineages often arise early in a group's history, even though there is no prior expectation for this tendency in datasets of extinct groups. The implications of these results for diversification histories and niche preemption are discussed.

  11. Indo-European languages tree by Levenshtein distance

    NASA Astrophysics Data System (ADS)

    Serva, M.; Petroni, F.

    2008-03-01

    The evolution of languages closely resembles the evolution of haploid organisms. This similarity has been recently exploited (Gray R. D. and Atkinson Q. D., Nature, 426 (2003) 435; Gray R. D. and Jordan F. M., Nature, 405 (2000) 1052) to construct language trees. The key point is the definition of a distance among all pairs of languages which is the analogous of a genetic distance. Many methods have been proposed to define these distances; one of these, used by glottochronology, computes the distance from the percentage of shared "cognates". Cognates are words inferred to have a common historical origin, and subjective judgment plays a relevant role in the identification process. Here we push closer the analogy with evolutionary biology and we introduce a genetic distance among language pairs by considering a renormalized Levenshtein distance among words with same meaning and averaging on all words contained in a Swadesh list (Swadesh M., Proc. Am. Philos. Soc., 96 (1952) 452). The subjectivity of process is consistently reduced and the reproducibility is highly facilitated. We test our method against the Indo-European group considering fifty different languages and the two hundred words of the Swadesh list for any of them. We find out a tree which closely resembles the one published in Gray and Atkinson (2003), with some significant differences.

  12. a Fast Method for Measuring the Similarity Between 3d Model and 3d Point Cloud

    NASA Astrophysics Data System (ADS)

    Zhang, Zongliang; Li, Jonathan; Li, Xin; Lin, Yangbin; Zhang, Shanxin; Wang, Cheng

    2016-06-01

    This paper proposes a fast method for measuring the partial Similarity between 3D Model and 3D point Cloud (SimMC). It is crucial to measure SimMC for many point cloud-related applications such as 3D object retrieval and inverse procedural modelling. In our proposed method, the surface area of model and the Distance from Model to point Cloud (DistMC) are exploited as measurements to calculate SimMC. Here, DistMC is defined as the weighted distance of the distances between points sampled from model and point cloud. Similarly, Distance from point Cloud to Model (DistCM) is defined as the average distance of the distances between points in point cloud and model. In order to reduce huge computational burdens brought by calculation of DistCM in some traditional methods, we define SimMC as the ratio of weighted surface area of model to DistMC. Compared to those traditional SimMC measuring methods that are only able to measure global similarity, our method is capable of measuring partial similarity by employing distance-weighted strategy. Moreover, our method is able to be faster than other partial similarity assessment methods. We demonstrate the superiority of our method both on synthetic data and laser scanning data.

  13. The Anatomical Distance of Functional Connections Predicts Brain Network Topology in Health and Schizophrenia

    PubMed Central

    Vértes, Petra E.; Stidd, Reva; Lalonde, François; Clasen, Liv; Rapoport, Judith; Giedd, Jay; Bullmore, Edward T.; Gogtay, Nitin

    2013-01-01

    The human brain is a topologically complex network embedded in anatomical space. Here, we systematically explored relationships between functional connectivity, complex network topology, and anatomical (Euclidean) distance between connected brain regions, in the resting-state functional magnetic resonance imaging brain networks of 20 healthy volunteers and 19 patients with childhood-onset schizophrenia (COS). Normal between-subject differences in average distance of connected edges in brain graphs were strongly associated with variation in topological properties of functional networks. In addition, a club or subset of connector hubs was identified, in lateral temporal, parietal, dorsal prefrontal, and medial prefrontal/cingulate cortical regions. In COS, there was reduced strength of functional connectivity over short distances especially, and therefore, global mean connection distance of thresholded graphs was significantly greater than normal. As predicted from relationships between spatial and topological properties of normal networks, this disorder-related proportional increase in connection distance was associated with reduced clustering and modularity and increased global efficiency of COS networks. Between-group differences in connection distance were localized specifically to connector hubs of multimodal association cortex. In relation to the neurodevelopmental pathogenesis of schizophrenia, we argue that the data are consistent with the interpretation that spatial and topological disturbances of functional network organization could arise from excessive “pruning” of short-distance functional connections in schizophrenia. PMID:22275481

  14. Maintaining vigorous activity attenuates 7-yr weight gain in 8340 runners.

    PubMed

    Williams, Paul T

    2007-05-01

    Body weight generally increases with aging in Western societies. Although training studies show that exercise produces acute weight loss, it is unclear whether the long-term maintenance of vigorous exercise attenuates the trajectory of age-related weight gain. Specifically, prior studies have not tested whether the maintenance of physical activity, in the absence of any change in activity, prevents weight gain. Prospective study of 6119 male and 2221 female runners whose running distances changed < 5 km x wk(-1) between baseline and follow-up surveys 7 yr later. On average, men who maintained modest (0-23 km x wk(-1)), intermediate (24-47 km x wk(-1)), or prolonged running distances (> or = 48 km x wk(-1)) all gained weight through age 64; however, those who maintained > or = 48 km x wk(-1) had one half the average annual weight gain of those who maintained < 24 km x wk(-1). For example, between the ages of 35 and 44 in men and 30 and 39 yr in women, those who maintained < 24 km x wk(-1) gained, on average, 2.1 and 2.9 kg more per decade than those averaging > 48 km x wk(-1). Age-related weight gain, and its attenuation by maintained exercise, were both greater in younger than in older men. Men's gains in waist circumference with age, and its attenuation by maintaining running, were the same in older and younger men. Regardless of age, women increased their body weight, waist circumference, and hip circumference over time, and these measurements were attenuated in proportion to their maintained running distance. In both sexes, running disproportionately prevented more extreme increases in weight. As they aged, men and women gained less weight in proportion to their levels of sustained vigorous activity. This long-term beneficial effect is in addition to the acute weight loss that occurs with increased activity.

  15. [Characteristics and its forming mechanism on grain size distribution of suspended matter at Changjiang Estuary].

    PubMed

    Pang, Chong-guang; Yu, Wei; Yang, Yang

    2010-03-01

    In July of 2008, under the natural condition of sea water, the Laser in-situ scattering and transmissometry (LISST-100X Type C) was used to measure grain size distribution spectrum and volume concentration of total suspended matter in the sea water, including flocs at different layers of 24 sampling stations at Changjiang Estuary and its adjacent sea. The characteristics and its forming mechanism on grain size distribution of total suspended matter were analyzed based on the observation data of LISST-100X Type C, and combining with the temperature, salinity and turbidity of sea water, simultaneously observed by Alec AAQ1183. The observation data showed that the average median grain size of total suspended matter was about 4.69 phi in the whole measured sea area, and the characteristics of grain size distribution was relatively poor sorted, wide kurtosis, and basically symmetrical. The conclusion could be drawn that vertically average volume concentration decreased with the distance from the coastline, while median grain size had an increase trend with the distance, for example, at 31.0 degrees N section, the depth-average median grain size had been increased from 11 microm up to 60 microm. With the increasing of distance from the coast, the concentration of fine suspended sediment reduced distinctly, nevertheless some relatively big organic matter or big flocs appeared in quantity, so its grain size would rise. The observation data indicated that the effective density was ranged from 246 kg/m3 to 1334 kg/m, with average was 613 kg/m3. When the concentration of total suspended matter was relatively high, median grain size of total suspended matter increased with the water depth, while effective density decreased with the depth, because of the faster settling velocity and less effective density of large flocs that of small flocs. As for station 37 and 44, their correlation coefficients between effective density and median grain size were larger than 0.9.

  16. Is a reduction in distance to nearest supermarket associated with BMI change among type 2 diabetes patients?

    PubMed

    Zhang, Y Tara; Laraia, Barbara A; Mujahid, Mahasin S; Blanchard, Samuel D; Warton, E Margaret; Moffet, Howard H; Karter, Andrew J

    2016-07-01

    We examined whether residing within 2 miles of a new supermarket opening was longitudinally associated with a change in body mass index (BMI). We identified 12 new supermarkets that opened between 2009 and 2010 in 8 neighborhoods. Using the Kaiser Permanente Northern California Diabetes Registry, we identified members with type 2 diabetes residing continuously in any of these neighborhoods 12 months prior to the first supermarket opening until 10 months following the opening of the last supermarket. Exposure was defined as a reduction (yes/no) in travel distance to the nearest supermarket as a result of a new supermarket opening. First difference regression models were used to estimate the impact of reduced supermarket distance on BMI, adjusting for longitudinal changes in patient and neighborhood characteristics. Among patients in the exposed group, new supermarket openings reduced travel distance to the nearest supermarket by 0.7 miles on average. However, reduced distance to nearest supermarket was not associated with BMI changes. Overall, we found no evidence that reduced supermarket distance was associated with reduced levels of obesity for residents with type 2 diabetes. Published by Elsevier Ltd.

  17. Is a reduction in distance to nearest supermarket associated with BMI change among type 2 diabetes patients?

    PubMed Central

    Zhang, Y. Tara; Laraia, Barbara A.; Mujahid, Mahasin S.; Blanchard, Samuel D.; Warton, E. Margaret; Moffet, Howard H.; Karter, Andrew J.

    2016-01-01

    We examined whether residing within 2 miles of a new supermarket opening was longitudinally associated with a change in body mass index (BMI). We identified 12 new supermarkets that opened between 2009–2010 in 8 neighborhoods. Using the Kaiser Permanente Northern California Diabetes Registry, we identified members with type 2 diabetes residing continuously in any of these neighborhoods 12 months prior to the first supermarket opening until 10 months following the opening of the last supermarket. Exposure was defined as a reduction (yes/no) in travel distance to the nearest supermarket as a result of a new supermarket opening. First difference regression models were used to estimate the impact of reduced supermarket distance on BMI, adjusting for longitudinal changes in patient and neighborhood characteristics. Among patients in the exposed group, new supermarket openings reduced travel distance to the nearest supermarket by 0.7 miles on average. However, reduced distance to nearest supermarket was not associated with BMI changes. Overall, we found no evidence that reduced supermarket distance was associated with reduced levels of obesity for residents with type 2 diabetes. PMID:27160530

  18. Laws of evolution of slip trace pattern and its parameters with deformation in [1.8.12] – single crystals of Ni{sub 3}Fe alloy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Teplyakova, Ludmila, E-mail: lat168@mail.ru; Koneva, Nina, E-mail: koneva@mail.ru; Kunitsyna, Tatyana, E-mail: kma11061990@mail.ru

    2016-01-15

    The slip trace pattern of Ni{sub 3}Fe alloy single crystals with the short range order oriented for a single slip were investigated on replica at different stages of deformation using the transmission diffraction electron microscopy method. The connection of staging with the formation of slip trace pattern and the change of its parameters were established. The number of local areas where two or more slip systems work is increased with the change of stages. In these conditions the character of slip localization in the primary slip system is changed from the packets to the homogeneous distribution. The distributions of themore » distances between slip traces and the shear power in slip traces were plotted. The correlation between the average value of the shear power in the primary slip traces and the average distance between them was revealed in this work. It was established that the rates of the average value growth of the relative local shear and the shear power in the slip traces reach the largest values at the transition stage.« less

  19. Effects of age and step length on joint kinetics during stepping task.

    PubMed

    Bieryla, Kathleen A; Buffinton, Christine

    2015-07-16

    Following a balance perturbation, a stepping response is commonly used to regain support, and the distance of the recovery step can vary. To date, no other studies have examined joint kinetics in young and old adults during increasing step distances, when participants are required to bring their rear foot forward. Therefore, the purpose of this study was to examine age-related differences in joint kinetics with increasing step distance. Twenty young and 20 old adults completed the study. Participants completed a step starting from double support, at an initial distance equal to the individual's average step length. The distance was increased by 10% body height until an unsuccessful attempt. A one-way, repeated measures ANOVA was used to determine the effects of age on joint kinetics during the maximum step distance. A two-way, repeated measures, mixed model ANOVA was used to determine the effects of age, step distance, and their interaction on joint kinetics during the first three step distances for all participants. Young adults completed a significantly longer step than old adults. During the maximum step, in general, kinetic measures were greater in the young than in the old. As step distance increased, all but one kinetic measure increased for both young and old adults. This study has shown the ability to discriminate between young and old adults, and could potentially be used in the future to distinguish between fallers and non-fallers. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Central stars of planetary nebulae in the Galactic bulge

    NASA Astrophysics Data System (ADS)

    Hultzsch, P. J. N.; Puls, J.; Méndez, R. H.; Pauldrach, A. W. A.; Kudritzki, R.-P.; Hoffmann, T. L.; McCarthy, J. K.

    2007-06-01

    Context: Optical high-resolution spectra of five central stars of planetary nebulae (CSPN) in the Galactic bulge have been obtained with Keck/HIRES in order to derive their parameters. Since the distance of the objects is quite well known, such a method has the advantage that stellar luminosities and masses can in principle be determined without relying on theoretical relations between both quantities. Aims: By alternatively combining the results of our spectroscopic investigation with evolutionary tracks, we obtain so-called spectroscopic distances, which can be compared with the known (average) distance of the bulge-CSPN. This offers the possibility to test the validity of model atmospheres and present date post-AGB evolution. Methods: We analyze optical H/He profiles of five Galactic bulge CSPN (plus one comparison object) by means of profile fitting based on state of the art non-LTE modeling tools, to constrain their basic atmospheric parameters (Teff, log g, helium abundance and wind strength). Masses and other stellar radius dependent quantities are obtained from both the known distances and from evolutionary tracks, and the results from both approaches are compared. Results: The major result of the present investigation is that the derived spectroscopic distances depend crucially on the applied reddening law. Assuming either standard reddening or values based on radio-Hβ extinctions, we find a mean distance of 9.0±1.6 kpc and 12.2±2.1 kpc, respectively. An “average extinction law” leads to a distance of 10.7±1.2 kpc, which is still considerably larger than the Galactic center distance of 8 kpc. In all cases, however, we find a remarkable internal agreement of the individual spectroscopic distances of our sample objects, within ±10% to ±15% for the different reddening laws. Conclusions: Due to the uncertain reddening correction, the analysis presented here cannot yet be regarded as a consistency check for our method, and a rigorous test of the CSPN evolution theory becomes only possible if this problem has been solved. The data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. Appendix A is only available in electronic form at http://www.aanda.org

  1. The Solar Swan Dive.

    ERIC Educational Resources Information Center

    Dilsaver, John S.; Siler, Joseph R.

    1991-01-01

    Solutions for a problem in which the time necessary for an object to fall into the sun from the average distance from the earth to the sun are presented. Both calculus- and noncalculus-based solutions are presented. A sample computer solution is included. (CW)

  2. Mottled duck (Anas fulvigula) movements in the Texas Chenier Plain Region

    USGS Publications Warehouse

    Moon, Jena A.; Haukos, David A.; Conway, Warren C.

    2015-01-01

    As a surrogate species for Strategic Habitat Conservation, the mottled duck (Anas fulgivula) is an indicator species to coastal marsh health and function. Currently, biologists have a relatively poor understanding of regional mottled duck movements. We outfitted adult female mottled ducks with solar satellite transmitters during summer 2009–2011. Movement patterns were measured among years and phenology, in relation to available habitat at the landscape level, and in association to potential disturbance. Movement distances were measured in ArcGIS and then evaluated using analysis of variance for independent variables of year, month, biological time period, and season. Average weekly distances traveled by mottled ducks were relatively short (<5,000m) compared to other waterfowl. Movement occurrence and distance were linked to biological season with longest distances documented during the molt period. Movements also differed among years, with drought conditions associated with longer movement distances. Magnitude of movements may be an indicator of habitat quality for mottled ducks in the Texas Chenier Plain Region. By focusing on providing large freshwater pools and fresh/intermediate marsh during the molt period, managers could positively impact mottled ducks.

  3. Polyproline and the “spectroscopic ruler” revisited with single-molecule fluorescence

    PubMed Central

    Schuler, Benjamin; Lipman, Everett A.; Steinbach, Peter J.; Kumke, Michael; Eaton, William A.

    2005-01-01

    To determine whether Förster resonance energy transfer (FRET) measurements can provide quantitative distance information in single-molecule fluorescence experiments on polypeptides, we measured FRET efficiency distributions for donor and acceptor dyes attached to the ends of freely diffusing polyproline molecules of various lengths. The observed mean FRET efficiencies agree with those determined from ensemble lifetime measurements but differ considerably from the values expected from Förster theory, with polyproline treated as a rigid rod. At donor–acceptor distances much less than the Förster radius R0, the observed efficiencies are lower than predicted, whereas at distances comparable to and greater than R0, they are much higher. Two possible contributions to the former are incomplete orientational averaging during the donor lifetime and, because of the large size of the dyes, breakdown of the point-dipole approximation assumed in Förster theory. End-to-end distance distributions and correlation times obtained from Langevin molecular dynamics simulations suggest that the differences for the longer polyproline peptides can be explained by chain bending, which considerably shortens the donor–acceptor distances. PMID:15699337

  4. How Different Marker Sets Affect Joint Angles in Inverse Kinematics Framework.

    PubMed

    Mantovani, Giulia; Lamontagne, Mario

    2017-04-01

    The choice of marker set is a source of variability in motion analysis. Studies exist which assess the performance of marker sets when direct kinematics is used, but these results cannot be extrapolated to the inverse kinematic framework. Therefore, the purpose of this study was to examine the sensitivity of kinematic outcomes to inter-marker set variability in an inverse kinematic framework. The compared marker sets were plug-in-gait, University of Ottawa motion analysis model and a three-marker-cluster marker set. Walking trials of 12 participants were processed in opensim. The coefficient of multiple correlations was very good for sagittal (>0.99) and transverse (>0.92) plane angles, but worsened for the transverse plane (0.72). Absolute reliability indices are also provided for comparison among studies: minimum detectable change values ranged from 3 deg for the hip sagittal range of motion to 16.6 deg of the hip transverse range of motion. Ranges of motion of hip and knee abduction/adduction angles and hip and ankle rotations were significantly different among the three marker configurations (P < 0.001), with plug-in-gait producing larger ranges of motion. Although the same model was used for all the marker sets, the resulting minimum detectable changes were high and clinically relevant, which warns for caution when comparing studies that use different marker configurations, especially if they differ in the joint-defining markers.

  5. Reliability and validity of a GPS-enabled iPhone "app" to measure physical activity.

    PubMed

    Benson, Amanda Clare; Bruce, Lyndell; Gordon, Brett Ashley

    2015-01-01

    This study assessed the validity and reliability of an iPhone "app" and two sport-specific global positioning system (GPS) units to monitor distance, intensity and contextual physical activity. Forty (23 female, 17 male) 18-55-year-olds completed two trials of six laps around a 400-m athletics track wearing GPSports Pro and WiSpi units (5 and 1 Hz) and an iPhone(TM) with a Motion X GPS(TM) "app" that used the inbuilt iPhone location services application programming interface to obtain its sampling rate (which is likely to be ≤1 Hz). Overall, the statistical agreement, assessed using t-tests and Bland-Altman plots, indicated an underestimation of the known track distance (2.400 km) and average speed by the Motion X GPS "app" and GPSports Pro while the GPSports WiSpi(TM) device overestimated these outcomes. There was a ≤3% variation between trials for distance and average speed when measured by any of the GPS devices. Thus, the smartphone "app" trialled could be considered as an accessible alternative to provide high-quality contextualised data to enable ubiquitous monitoring and modification of programmes to ensure appropriate intensity and type of physical activity is prescribed and more importantly adhered to.

  6. Voluntary resistance running induces increased hippocampal neurogenesis in rats comparable to load-free running.

    PubMed

    Lee, Min Chul; Inoue, Koshiro; Okamoto, Masahiro; Liu, Yu Fan; Matsui, Takashi; Yook, Jang Soo; Soya, Hideaki

    2013-03-14

    Recently, we reported that voluntary resistance wheel running with a resistance of 30% of body weight (RWR), which produces shorter distances but higher work levels, enhances spatial memory associated with hippocampal brain-derived neurotrophic factor (BDNF) signaling compared to wheel running without a load (WR) [17]. We thus hypothesized that RWR promotes adult hippocampal neurogenesis (AHN) as a neuronal substrate underlying this memory improvement. Here we used 10-week-old male Wistar rats divided randomly into sedentary (Sed), WR, and RWR groups. All rats were injected intraperitoneally with the thymidine analogue 5-Bromo-2'-deoxuridine (BrdU) for 3 consecutive days before wheel running. We found that even when the average running distance decreased by about half, the average work levels significantly increased in the RWR group, which caused muscular adaptation (oxidative capacity) for fast-twitch plantaris muscle without causing any negative stress effects. Additionally, immunohistochemistry revealed that the total BrdU-positive cells and newborn mature cells (BrdU/NeuN double-positive) in the dentate gyrus increased in both the WR and RWR groups. These results provide new evidence that RWR has beneficial effects on AHN comparable to WR, even with short running distances. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. Tetra-μ3-iodido-tetra­kis­[(tri-n-butyl­phosphane-κP)copper(I)

    PubMed Central

    Klenk, Simon; Frey, Wolfgang; Bubrin, Martina; Laschat, Sabine

    2014-01-01

    The title complex, [Cu4I4(C12H27P)4], crystallizes with six mol­ecules in the unit cell and with three independent one-third mol­ecule fragments, completed by application of the relevant symmetry operators, in the asymmetric unit. The tetranuclear copper core shows a tetrahedral geometry (site symmetry 3..). The I atoms also form a tetra­hedron, with I⋯I distances of 4.471 (1) Å. Both tetra­hedra show an orientation similar to that of a pair of self-dual platonic bodies. The edges of the I-tetra­hedral structure are capped to the face centers of the Cu-tetra­hedron and vice versa. The Cuface⋯I distances are 2.18 Å (averaged) and the Iface⋯Cu distances are 0.78 Å (averaged). As a geometric consequence of these properties there are eight distorted trigonal–bipyramidal polyhedra evident, wherein each trigonal face builds up the equatorial site and the opposite Cu⋯I positions form the axial site. As expected, the n-butyl moieties are highly flexible, resulting in large elongations of their anisotropic displacement parameters. Some C atoms of the n-butyl groups were needed to fix alternative discrete disordered positions. PMID:24826086

  8. Prediction of maximum earthquake intensities for the San Francisco Bay region

    USGS Publications Warehouse

    Borcherdt, Roger D.; Gibbs, James F.

    1975-01-01

    The intensity data for the California earthquake of April 18, 1906, are strongly dependent on distance from the zone of surface faulting and the geological character of the ground. Considering only those sites (approximately one square city block in size) for which there is good evidence for the degree of ascribed intensity, the empirical relation derived between 1906 intensities and distance perpendicular to the fault for 917 sites underlain by rocks of the Franciscan Formation is: Intensity = 2.69 - 1.90 log (Distance) (km). For sites on other geologic units intensity increments, derived with respect to this empirical relation, correlate strongly with the Average Horizontal Spectral Amplifications (AHSA) determined from 99 three-component recordings of ground motion generated by nuclear explosions in Nevada. The resulting empirical relation is: Intensity Increment = 0.27 +2.70 log (AHSA), and average intensity increments for the various geologic units are -0.29 for granite, 0.19 for Franciscan Formation, 0.64 for the Great Valley Sequence, 0.82 for Santa Clara Formation, 1.34 for alluvium, 2.43 for bay mud. The maximum intensity map predicted from these empirical relations delineates areas in the San Francisco Bay region of potentially high intensity from future earthquakes on either the San Andreas fault or the Hazard fault.

  9. A framework of multitemplate ensemble for fingerprint verification

    NASA Astrophysics Data System (ADS)

    Yin, Yilong; Ning, Yanbin; Ren, Chunxiao; Liu, Li

    2012-12-01

    How to improve performance of an automatic fingerprint verification system (AFVS) is always a big challenge in biometric verification field. Recently, it becomes popular to improve the performance of AFVS using ensemble learning approach to fuse related information of fingerprints. In this article, we propose a novel framework of fingerprint verification which is based on the multitemplate ensemble method. This framework is consisted of three stages. In the first stage, enrollment stage, we adopt an effective template selection method to select those fingerprints which best represent a finger, and then, a polyhedron is created by the matching results of multiple template fingerprints and a virtual centroid of the polyhedron is given. In the second stage, verification stage, we measure the distance between the centroid of the polyhedron and a query image. In the final stage, a fusion rule is used to choose a proper distance from a distance set. The experimental results on the FVC2004 database prove the improvement on the effectiveness of the new framework in fingerprint verification. With a minutiae-based matching method, the average EER of four databases in FVC2004 drops from 10.85 to 0.88, and with a ridge-based matching method, the average EER of these four databases also decreases from 14.58 to 2.51.

  10. Transformation of cyclodextrin glucanotransferase (CGTase) from aqueous suspension to fine solid particles via electrospraying.

    PubMed

    Saallah, Suryani; Naim, M Nazli; Mokhtar, Mohd Noriznan; Abu Bakar, Noor Fitrah; Gen, Masao; Lenggoro, I Wuled

    2014-10-01

    In this study, the potential of electrohydrodynamic atomization or electrospraying to produce nanometer-order CGTase particles from aqueous suspension was demonstrated. CGTase enzyme was prepared in acetate buffer solution (1% v/v), followed by electrospraying in stable Taylor cone-jet mode. The deposits were collected on aluminium foil (collector) at variable distances from the tip of spraying needle, ranging from 10 to 25 cm. The Coulomb fission that occurs during electrospraying process successfully transformed the enzyme to the solid state without any functional group deterioration. The functional group verification was conducted by FTIR analysis. Comparison between the deposit and the as-received enzyme in dry state indicates almost identical spectra. By increasing the distance of the collector from the needle tip, the average particle size of the solidified enzyme was reduced from 200±117 nm to 75±34 nm. The average particle sizes produced from the droplet fission were in agreement with the scaling law models. Enzyme activity analysis showed that the enzyme retained its initial activity after the electrospraying process. The enzyme particles collected at the longest distance (25 cm) demonstrated the highest enzyme activity, which indicates that the activity was controlled by the enzyme particle size. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Validation of Aircraft Noise Models at Lower Levels of Exposure

    NASA Technical Reports Server (NTRS)

    Page, Juliet A.; Plotkin, Kenneth J.; Carey, Jeffrey N.; Bradley, Kevin A.

    1996-01-01

    Noise levels around airports and airbases in the United States arc computed via the FAA's Integrated Noise Model (INM) or the Air Force's NOISEMAP (NMAP) program. These models were originally developed for use in the vicinity of airports, at distances which encompass a day night average sound level in decibels (Ldn) of 65 dB or higher. There is increasing interest in aircraft noise at larger distances from the airport. including en-route noise. To evaluate the applicability of INM and NMAP at larger distances, a measurement program was conducted at a major air carrier airport with monitoring sites located in areas exposed to an Ldn of 55 dB and higher. Automated Radar Terminal System (ARTS) radar tracking data were obtained to provide actual flight parameters and positive identification of aircraft. Flight operations were grouped according to aircraft type. stage length, straight versus curved flight tracks, and arrival versus departure. Sound exposure levels (SEL) were computed at monitoring locations, using the INM, and compared with measured values. While individual overflight SEL data was characterized by a high variance, analysis performed on an energy-averaging basis indicates that INM and similar models can be applied to regions exposed to an Ldn of 55 dB with no loss of reliability.

  12. Towards online iris and periocular recognition under relaxed imaging constraints.

    PubMed

    Tan, Chun-Wei; Kumar, Ajay

    2013-10-01

    Online iris recognition using distantly acquired images in a less imaging constrained environment requires the development of a efficient iris segmentation approach and recognition strategy that can exploit multiple features available for the potential identification. This paper presents an effective solution toward addressing such a problem. The developed iris segmentation approach exploits a random walker algorithm to efficiently estimate coarsely segmented iris images. These coarsely segmented iris images are postprocessed using a sequence of operations that can effectively improve the segmentation accuracy. The robustness of the proposed iris segmentation approach is ascertained by providing comparison with other state-of-the-art algorithms using publicly available UBIRIS.v2, FRGC, and CASIA.v4-distance databases. Our experimental results achieve improvement of 9.5%, 4.3%, and 25.7% in the average segmentation accuracy, respectively, for the UBIRIS.v2, FRGC, and CASIA.v4-distance databases, as compared with most competing approaches. We also exploit the simultaneously extracted periocular features to achieve significant performance improvement. The joint segmentation and combination strategy suggest promising results and achieve average improvement of 132.3%, 7.45%, and 17.5% in the recognition performance, respectively, from the UBIRIS.v2, FRGC, and CASIA.v4-distance databases, as compared with the related competing approaches.

  13. VizieR Online Data Catalog: The distance modulus of the LMC (Kovacs, 2000)

    NASA Astrophysics Data System (ADS)

    Kovacs, G.

    2000-11-01

    This table provides periods, intensity averaged V magnitudes and magnitude averaged V-Rc (Johnson V & Kron-Cousins R) colors of the MACHO LMC double-mode RR Lyrae variables employed in the above paper. For the calculation of the averages, an iterative 3-sigma condition was used to omit outliers. Further references (coordinates, amplitude ratios, etc.) to these variables can be found in Alcock et al. (1997ApJ...482...89A) and in Alcock et al. (2000, Cat. ). Trasformation to the standard system has been performed in accordance with Alcock et al. (1999PASP..111.1539A). (1 data file).

  14. SETI and SEH (Statistical Equation for Habitables)

    NASA Astrophysics Data System (ADS)

    Maccone, Claudio

    2011-01-01

    The statistics of habitable planets may be based on a set of ten (and possibly more) astrobiological requirements first pointed out by Stephen H. Dole in his book "Habitable planets for man" (1964). In this paper, we first provide the statistical generalization of the original and by now too simplistic Dole equation. In other words, a product of ten positive numbers is now turned into the product of ten positive random variables. This we call the SEH, an acronym standing for "Statistical Equation for Habitables". The mathematical structure of the SEH is then derived. The proof is based on the central limit theorem (CLT) of Statistics. In loose terms, the CLT states that the sum of any number of independent random variables, each of which may be arbitrarily distributed, approaches a Gaussian (i.e. normal) random variable. This is called the Lyapunov form of the CLT, or the Lindeberg form of the CLT, depending on the mathematical constraints assumed on the third moments of the various probability distributions. In conclusion, we show that The new random variable NHab, yielding the number of habitables (i.e. habitable planets) in the Galaxy, follows the lognormal distribution. By construction, the mean value of this lognormal distribution is the total number of habitable planets as given by the statistical Dole equation. But now we also derive the standard deviation, the mode, the median and all the moments of this new lognormal NHab random variable. The ten (or more) astrobiological factors are now positive random variables. The probability distribution of each random variable may be arbitrary. The CLT in the so-called Lyapunov or Lindeberg forms (that both do not assume the factors to be identically distributed) allows for that. In other words, the CLT "translates" into our SEH by allowing an arbitrary probability distribution for each factor. This is both astrobiologically realistic and useful for any further investigations. An application of our SEH then follows. The (average) distancebetween any two nearby habitable planets in the Galaxy may be shown to be inversely proportional to the cubic root of NHab. Then, in our approach, this distance becomes a new random variable. We derive the relevant probability density function, apparently previously unknown and dubbed "Maccone distribution" by Paul Davies in 2008. Data Enrichment Principle. It should be noticed that ANY positive number of random variables in the SEH is compatible with the CLT. So, our generalization allows for many more factors to be added in the future as long as more refined scientific knowledge about each factor will be known to the scientists. This capability to make room for more future factors in the SEH we call the "Data Enrichment Principle", and we regard it as the key to more profound future results in the fields of Astrobiology and SETI. A practical example is then given of how our SEH works numerically. We work out in detail the case where each of the ten random variables is uniformly distributed around its own mean value as given by Dole back in 1964 and has an assumed standard deviation of 10%. The conclusion is that the average number of habitable planets in the Galaxy should be around 100 million±200 million, and the average distance in between any couple of nearby habitable planets should be about 88 light years±40 light years. Finally, we match our SEH results against the results of the Statistical Drake Equation that we introduced in our 2008 IAC presentation. As expected, the number of currently communicating ET civilizations in the Galaxy turns out to be much smaller than the number of habitable planets (about 10,000 against 100 million, i.e. one ET civilization out of 10,000 habitable planets). And the average distance between any two nearby habitable planets turns out to be much smaller than the average distance between any two neighboring ET civilizations: 88 light years vs. 2000 light years, respectively. This means an ET average distance about 20 times higher than the average distance between any couple of adjacent habitable planets.

  15. Physics-based method to validate and repair flaws in protein structures

    PubMed Central

    Martin, Osvaldo A.; Arnautova, Yelena A.; Icazatti, Alejandro A.; Scheraga, Harold A.; Vila, Jorge A.

    2013-01-01

    A method that makes use of information provided by the combination of 13Cα and 13Cβ chemical shifts, computed at the density functional level of theory, enables one to (i) validate, at the residue level, conformations of proteins and detect backbone or side-chain flaws by taking into account an ensemble average of chemical shifts over all of the conformations used to represent a protein, with a sensitivity of ∼90%; and (ii) provide a set of (χ1/χ2) torsional angles that leads to optimal agreement between the observed and computed 13Cα and 13Cβ chemical shifts. The method has been incorporated into the CheShift-2 protein validation Web server. To test the reliability of the provided set of (χ1/χ2) torsional angles, the side chains of all reported conformations of five NMR-determined protein models were refined by a simple routine, without using NOE-based distance restraints. The refinement of each of these five proteins leads to optimal agreement between the observed and computed 13Cα and 13Cβ chemical shifts for ∼94% of the flaws, on average, without introducing a significantly large number of violations of the NOE-based distance restraints for a distance range ≤ 0.5 Ǻ, in which the largest number of distance violations occurs. The results of this work suggest that use of the provided set of (χ1/χ2) torsional angles together with other observables, such as NOEs, should lead to a fast and accurate refinement of the side-chain conformations of protein models. PMID:24082119

  16. Evaluation of the isometry of different points of the patella and femur for medial patellofemoral ligament reconstruction.

    PubMed

    Gobbi, Riccardo Gomes; Pereira, César Augusto Martins; Sadigursky, David; Demange, Marco Kawamura; Tírico, Luis Eduardo Passarelli; Pécora, José Ricardo; Camanho, Gilberto Luis

    2016-10-01

    The location of patellar and femoral fixation of the graft in medial patellofemoral ligament reconstructions has been widely discussed. This study aimed to assess the distances between different patellar and femoral fixation points to identify the least anisometric pairs of points. Ten cadaver knees were attached to an apparatus that simulated an active range of motion of 120°, with three metallic markers fixed onto the medial side of the patella, and seven markings onto the medial epicondyle. The examined points included the proximal patella pole (1), the patellar center (3), the midpoint between points 1 and 3 (2), a point directly on the epicondyle (6), points 5mm anterior (5) and posterior (7) to the epicondyle, points 5mm anterior to point 5 (4) and 5mm posterior to point 7 (8), and points 5mm proximal (9) and distal (10) to the epicondyle. The distances between patella and femur points were measured by a photogrammetry system at 15° intervals. The pair of points that exhibited the lowest average variability in distance, and hence was the most isometric, was the patella center combined with the anterior to the medial femoral epicondyle. The pairs of points that exhibited the highest average variability in distance, and hence were the least isometric, were the ones located distal or posterior to the medial femoral epicondyle, with less influence by the patellar location. Surgeons should avoid positioning the graft distally or posterior to the epicondyle due to the increase in anisometry. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Physics-based method to validate and repair flaws in protein structures.

    PubMed

    Martin, Osvaldo A; Arnautova, Yelena A; Icazatti, Alejandro A; Scheraga, Harold A; Vila, Jorge A

    2013-10-15

    A method that makes use of information provided by the combination of (13)C(α) and (13)C(β) chemical shifts, computed at the density functional level of theory, enables one to (i) validate, at the residue level, conformations of proteins and detect backbone or side-chain flaws by taking into account an ensemble average of chemical shifts over all of the conformations used to represent a protein, with a sensitivity of ∼90%; and (ii) provide a set of (χ1/χ2) torsional angles that leads to optimal agreement between the observed and computed (13)C(α) and (13)C(β) chemical shifts. The method has been incorporated into the CheShift-2 protein validation Web server. To test the reliability of the provided set of (χ1/χ2) torsional angles, the side chains of all reported conformations of five NMR-determined protein models were refined by a simple routine, without using NOE-based distance restraints. The refinement of each of these five proteins leads to optimal agreement between the observed and computed (13)C(α) and (13)C(β) chemical shifts for ∼94% of the flaws, on average, without introducing a significantly large number of violations of the NOE-based distance restraints for a distance range ≤ 0.5 , in which the largest number of distance violations occurs. The results of this work suggest that use of the provided set of (χ1/χ2) torsional angles together with other observables, such as NOEs, should lead to a fast and accurate refinement of the side-chain conformations of protein models.

  18. Relationships between Training Load, Salivary Cortisol Responses and Performance during Season Training in Middle and Long Distance Runners

    PubMed Central

    Balsalobre-Fernández, Carlos; Tejero-González, Carlos Mª; del Campo-Vecino, Juan

    2014-01-01

    Purpose Monitoring training from a multifactorial point of view is of great importance in elite endurance athletes. This study aims to analyze the relationships between indicators of training load, hormonal status and neuromuscular performance, and to compare these values with competition performance, in elite middle and long-distance runners. Method Fifteen elite middle and long-distance runners (12 men, 3 women; age = 26.3±5.1 yrs) were measured for training volume, training zone and session rate of perceived exertion (RPE) (daily), countermovement jump (CMJ) and salivary free cortisol (weekly) for 39 weeks (i.e., the whole season). Competition performance was also observed throughout the study, registering the season best and worst competitions. Results Season average salivary free cortisol concentrations correlate significantly with CMJ (r = −0.777) and RPE (r = 0.551). Also, weekly averages of CMJ significantly correlates with RPE (r = −0.426), distance run (r = −0.593, p<0.001) and training zone (r = 0.437, p<0.05). Finally, it was found that the CMJ (+8.5%, g = 0.65) and the RPE (−17.6%, g = 0.94) measured the week before the best competition performance of the season were significantly different compared with the measurement conducted the week before the season’s worst competition performance. Conclusions Monitoring weekly measurements of CMJ and RPE could be recommended to control training process of such athletes in a non-invasive, field-based, systematic way. PMID:25153137

  19. Comparing and combining distance-based and character-based approaches for barcoding turtles.

    PubMed

    Reid, B N; LE, M; McCord, W P; Iverson, J B; Georges, A; Bergmann, T; Amato, G; Desalle, R; Naro-Maciel, E

    2011-11-01

    Molecular barcoding can serve as a powerful tool in wildlife forensics and may prove to be a vital aid in conserving organisms that are threatened by illegal wildlife trade, such as turtles (Order Testudines). We produced cytochrome oxidase subunit one (COI) sequences (650 bp) for 174 turtle species and combined these with publicly available sequences for 50 species to produce a data set representative of the breadth of the order. Variability within the barcode region was assessed, and the utility of both distance-based and character-based methods for species identification was evaluated. For species in which genetic material from more than one individual was available (n = 69), intraspecific divergences were 1.3% on average, although divergences greater than the customary 2% barcode threshold occurred within 15 species. High intraspecific divergences could indicate species with a high degree of internal genetic structure or possibly even cryptic species, although introgression is also probable in some of these taxa. Divergences between species of the same genus were 6.4% on average; however, 49 species were <2% divergent from congeners. Low levels of interspecific divergence could be caused by recent evolutionary radiations coupled with the low rates of mtDNA evolution previously observed in turtles. Complementing distance-based barcoding with character-based methods for identifying diagnostic sets of nucleotides provided better resolution in several cases where distance-based methods failed to distinguish species. An online identification engine was created to provide character-based identifications. This study constitutes the first comprehensive barcoding effort for this seriously threatened order. © 2011 Blackwell Publishing Ltd.

  20. Disturbance Distance: Combining a process based ecosystem model and remote sensing data to map the vulnerability of U.S. forested ecosystems to potentially altered disturbance rates

    NASA Astrophysics Data System (ADS)

    Dolan, K. A.

    2015-12-01

    Disturbance plays a critical role in shaping the structure and function of forested ecosystems as well as the ecosystem services they provide, including but not limited to: carbon storage, biodiversity habitat, water quality and flow, and land atmosphere exchanges of energy and water. In addition, recent studies suggest that disturbance rates may increase in the future under altered climate and land use scenarios. Thus understanding how vulnerable forested ecosystems are to potential changes in disturbance rates is of high importance. This study calculated the theoretical threshold rate of disturbance for which forest ecosystems could no longer be sustained (λ*) across the Coterminous U.S. using an advanced process based ecosystem model (ED). Published rates of disturbance (λ) in 50 study sites were obtained from the North American Forest Disturbance (NAFD) program. Disturbance distance (λ* - λ) was calculated for each site by differencing the model based threshold under current climate conditions and average observed rates of disturbance over the last quarter century. Preliminary results confirm all sample forest sites have current average rates of disturbance below λ*, but there were interesting patterns in the recorded disturbance distances. In general western sites had much smaller disturbance distances, suggesting higher vulnerability to change, while eastern sites showed larger buffers. Ongoing work is being conducted to assess the vulnerability of these sites in the context of potential future changes by propagating scenarios of future climate and land-use change through the analysis.

  1. Attacking 22 entries in rugby union: running demands and differences between successful and unsuccessful entries.

    PubMed

    Tierney, P; Tobin, D P; Blake, C; Delahunt, E

    2017-12-01

    Global Positioning System (GPS) technology is commonly utilized in team sports, including rugby union. It has been used to describe the average running demands of rugby union. This has afforded an enhanced understanding of the physical fitness requirements for players. However, research in team sports has suggested that training players relative to average demands may underprepare them for certain scenarios within the game. To date, no research has investigated the running demands of attacking 22 entries in rugby union. Additionally, no research has been undertaken to determine whether differences exist in the running intensity of successful and unsuccessful attacking 22 entries in rugby union. The first aim of this study was to describe the running intensity of attacking 22 entries. The second aim of this study was to investigate whether differences exist in the running intensity of successful and unsuccessful attacking 22 entries. Running intensity was measured using meters per minute (m min -1 ) for (a) total distance, (b) running distance, (c) high-speed running distance, and (d) very high-speed running distance. This study provides normative data for the running intensity of attacking 22 entries in rugby union. Forwards achieved greater high-speed running intensity in successful (3.6 m min -1 ) compared to unsuccessful (1.8 m min -1 ) attacking 22 entries. Forwards should try and achieve greater high-speed running intensity in attacking 22 entries to increase the likelihood of successful outcomes during this period of gameplay. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Relationship of the actual thick intraocular lens optic to the thin lens equivalent.

    PubMed

    Holladay, J T; Maverick, K J

    1998-09-01

    To theoretically derive and empirically validate the relationship between the actual thick intraocular lens and the thin lens equivalent. Included in the study were 12 consecutive adult patients ranging in age from 54 to 84 years (mean +/- SD, 73.5 +/- 9.4 years) with best-corrected visual acuity better than 20/40 in each eye. Each patient had bilateral intraocular lens implants of the same style, placed in the same location (bag or sulcus) by the same surgeon. Preoperatively, axial length, keratometry, refraction, and vertex distance were measured. Postoperatively, keratometry, refraction, vertex distance, and the distance from the vertex of the cornea to the anterior vertex of the intraocular lens (AV(PC1)) were measured. Alternatively, the distance (AV(PC1)) was then back-calculated from the vergence formula used for intraocular lens power calculations. The average (+/-SD) of the absolute difference in the two methods was 0.23 +/- 0.18 mm, which would translate to approximately 0.46 diopters. There was no statistical difference between the measured and calculated values; the Pearson product-moment correlation coefficient from linear regression was 0.85 (r2 = .72, F = 56). The average intereye difference was -0.030 mm (SD, 0.141 mm; SEM, 0.043 mm) using the measurement method and +0.124 mm (SD, 0.412 mm; SEM, 0.124 mm) using the calculation method. The relationship between the actual thick intraocular lens and the thin lens equivalent has been determined theoretically and demonstrated empirically. This validation provides the manufacturer and surgeon additional confidence and utility for lens constants used in intraocular lens power calculations.

  3. Estimation of life times and diffusion distances of radicals involved in x- ray-induced DNA strand breaks of killing of mammalian cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roots, R; Okada, S

    1975-11-01

    We have used a mammalian tissue culture system to calculate the life times and diffusion distances in DNA scissions as well as cell killing for the three main products of water radiolysis: OH, H, and e$sup -$/sub aq/. Using various alcohols as radical scavengers, the average life time for OH in DNA single-strand breaks was calculated to be about 4 x 10$sup -9$ sec. Using the same data and published rate constants, the apparent life time of H atoms was calculated to vary from about 2 x 10$sup -7$ to 4 x 10$sup -6$ sec and, similarly, the calculated lifemore » time of the hydrated electron was found to vary more than was the case for OH. From these life times, the radical diffusion distances were estimated to be approximately 60 A for OH, which is reasonable, but the values for both H and e$sup -$/sub aq/ were unrealistically large, i.e., 880 to 4040 A for H and 9590 to 19,810 A for e$sup -$/sub aq/. In cell killing, the OH radical life time was estimated to be about 8.7 x 10$sup -9$ sec which gives an average diffusion distance for this radical of about 93 A. Our data support the idea that OH is the radical species primarily responsible for the indirect effect in radiation injury measured as DNA single-strand breaks or cell killing, and that H and e$sup -$/sub aq/ are not significantly involved. (auth)« less

  4. Increased vertebral bone mineral in response to reduced exercise in amenorrheic runners.

    PubMed

    Lindberg, J S; Powell, M R; Hunt, M M; Ducey, D E; Wade, C E

    1987-01-01

    Seven female runners found to have exercise-induced amenorrhea and decreased bone mineral were reevaluated after 15 months. During the 15-month period, four runners took supplemental calcium and reduced their weekly running distance by 43%, resulting in an average 5% increase in body weight, increased estradiol levels and eumenorrhea. Bone mineral content increased from 1.003+/-0.097 to 1.070+/-0.089 grams per cm.(2) Three runners continued to have amenorrhea, with no change in running distance or body weight. Estradiol levels remained abnormally low and there was no significant change in the bone mineral content, although all three took supplemental calcium. We found that early osteopenia associated with exercise-induced menstrual dysfunction improved when runners reduced their running distance, gained weight and became eumenorrheic.

  5. Assessment of Andragogical Attributes of Distance Learners

    NASA Astrophysics Data System (ADS)

    Hashim, Rugayah Gy; Ahmad, Hashim; Ahmad, Nor'aini

    The purpose of this research was to assess the andragogical attribute of adult students engaged in distance learning, specifically, with regards to the main construct, cognitive engagement versus academic achievement. Five hundred students were sampled and the response rate was 33.8%. From the analyses, the overall mean score for cognitive engagement is 3.75 from a scale of one to seven. The results indicated that knowledge gained through the e-distance learning is low and this evidence correlates to the average academic performance or CGPA of the respondents, which is between 2.50-2.99. The findings indicated a low level of integration and motivation in learning and consequently it is suggested that training programs and additional course revisions be integrated into the curriculum to ensure the chances of student success and reduce attrition rate.

  6. Point-to-point migration functions and gravity model renormalization: approaches to aggregation in spatial interaction modeling.

    PubMed

    Slater, P B

    1985-08-01

    Two distinct approaches to assessing the effect of geographic scale on spatial interactions are modeled. In the first, the question of whether a distance deterrence function, which explains interactions for one system of zones, can also succeed on a more aggregate scale, is examined. Only the two-parameter function for which it is found that distances between macrozones are weighted averaged of distances between component zones is satisfactory in this regard. Estimation of continuous (point-to-point) functions--in the form of quadrivariate cubic polynomials--for US interstate migration streams, is then undertaken. Upon numerical integration, these higher order surfaces yield predictions of interzonal and intrazonal movements at any scale of interest. Test of spatial stationarity, isotropy, and symmetry of interstate migration are conducted in this framework.

  7. Airborne space laser communication system and experiments

    NASA Astrophysics Data System (ADS)

    Li, Xiao-Ming; Zhang, Li-zhong; Meng, Li-Xin

    2015-11-01

    Airborne space laser communication is characterized by its high speed, anti-electromagnetic interference, security, easy to assign. It has broad application in the areas of integrated space-ground communication networking, military communication, anti-electromagnetic communication. This paper introduce the component and APT system of the airborne laser communication system design by Changchun university of science and technology base on characteristic of airborne laser communication and Y12 plan, especially introduce the high communication speed and long distance communication experiment of the system that among two Y12 plans. In the experiment got the aim that the max communication distance 144Km, error 10-6 2.5Gbps - 10-7 1.5Gbps capture probability 97%, average capture time 20s. The experiment proving the adaptability of the APT and the high speed long distance communication.

  8. 47 CFR 27.60 - TV/DTV interference protection criteria.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... average terrain, the distance to the radio path horizon will be calculated assuming smooth earth. If the... Section 27.60 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Technical Standards § 27.60 TV/DTV interference protection...

  9. Pokémon GO and Physical Activity in Asia: Multilevel Study.

    PubMed

    Ma, Ben D; Ng, Sai Leung; Schwanen, Tim; Zacharias, John; Zhou, Mudi; Kawachi, Ichiro; Sun, Guibo

    2018-06-15

    Physical activity has long been considered as an important component of a healthy lifestyle. Although many efforts have been made to promote physical activity, there is no effective global intervention for physical activity promotion. Some researchers have suggested that Pokémon GO, a location-based augmented reality game, was associated with a short-term increase in players' physical activity on a global scale, but the details are far from clear. The objective of our study was to study the relationship between Pokémon GO use and players' physical activity and how the relationship varies across players with different physical activity levels. We conducted a field study in Hong Kong to investigate if Pokémon GO use was associated with physical activity. Pokémon GO players were asked to report their demographics through a survey; data on their Pokémon GO behaviors and daily walking and running distances were collected from their mobile phones. Participants (n=210) were Hong Kong residents, aged 13 to 65 years, who played Pokémon GO using iPhone 5 or 6 series in 5 selected types of built environment. We measured the participants' average daily walking and running distances over a period of 35 days, from 14 days before to 21 days after game installation. Multilevel modeling was used to identify and examine the predictors (including Pokémon GO behaviors, weather, demographics, and built environment) of the relationship between Pokémon GO use and daily walking and running distances. The average daily walking and running distances increased by 18.1% (0.96 km, approximately 1200 steps) in the 21 days after the participants installed Pokémon GO compared with the average distances over the 14 days before installation (P<.001). However, this association attenuated over time and was estimated to disappear 24 days after game installation. Multilevel models indicated that Pokémon GO had a stronger and more lasting association among the less physically active players compared with the physically active ones (P<.001). Playing Pokémon GO in green space had a significant positive relationship with daily walking and running distances (P=.03). Moreover, our results showed that whether Pokémon GO was played, the number of days played, weather (total rainfall, bright sunshine, mean air temperature, and mean wind speed), and demographics (age, gender, income, education, and body mass index) were associated with daily walking and running distances. Pokémon GO was associated with a short-term increase in the players' daily walking and running distances; this association was especially strong among less physically active participants. Pokémon GO can build new links between humans and green space and encourage people to engage in physical activity. Our results show that location-based augmented reality games, such as Pokémon GO, have the potential to be a global public health intervention tool. ©Ben D Ma, Sai Leung Ng, Tim Schwanen, John Zacharias, Mudi Zhou, Ichiro Kawachi, Guibo Sun. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 15.06.2018.

  10. Energy cost of wheel running in house mice: implications for coadaptation of locomotion and energy budgets.

    PubMed

    Koteja, P; Swallow, J G; Carter, P A; Garland, T

    1999-01-01

    Laboratory house mice (Mus domesticus) that had experienced 10 generations of artificial selection for high levels of voluntary wheel running ran about 70% more total revolutions per day than did mice from random-bred control lines. The difference resulted primarily from increased average velocities rather than from increased time spent running. Within all eight lines (four selected, four control), females ran more than males. Average daily running distances ranged from 4.4 km in control males to 11.6 km in selected females. Whole-animal food consumption was statistically indistinguishable in the selected and control lines. However, mice from selected lines averaged approximately 10% smaller in body mass, and mass-adjusted food consumption was 4% higher in selected lines than in controls. The incremental cost of locomotion (grams food/revolution), computed as the partial regression slope of food consumption on revolutions run per day, did not differ between selected and control mice. On a 24-h basis, the total incremental cost of running (covering a distance) amounted to only 4.4% of food consumption in the control lines and 7.5% in the selected ones. However, the daily incremental cost of time active is higher (15.4% and 13.1% of total food consumption in selected and control lines, respectively). If wheel running in the selected lines continues to increase mainly by increases in velocity, then constraints related to energy acquisition are unlikely to be an important factor limiting further selective gain. More generally, our results suggest that, in small mammals, a substantial evolutionary increase in daily movement distances can be achieved by increasing running speed, without remarkable increases in total energy expenditure.

  11. Percutaneous CT-guided radiofrequency ablation of renal cell carcinoma: efficacy of organ displacement by injection of 5% dextrose in water into the retroperitoneum.

    PubMed

    Arellano, Ronald S; Garcia, Rodrigo G; Gervais, Debra A; Mueller, Peter R

    2009-12-01

    The objective of this study was to evaluate the effectiveness of CT-guided injection of 5% dextrose in water solution (D5W) into the retroperitoneum to displace organs adjacent to renal cell carcinoma. An interventional radiology database was searched to identify the cases of patients who underwent CT-guided percutaneous radiofrequency ablation of biopsy-proven renal cell carcinoma in which D5W was injected into the retroperitoneal space to displace structures away from the targeted renal tumor. The number of organs displaced and the distance between the renal tumor and adjacent organs before and after displacement with D5W were assessed. The cases of 135 patients with 139 biopsy-proven renal cell carcinomas who underwent 154 percutaneous CT-guided radiofrequency ablation procedures were found in the search. Thirty-one patients with 33 renal cell carcinomas underwent 36 ablation procedures after injection of D5W into the retroperitoneal space. Fifty-five organs were displaced away from renal cell carcinoma with this technique. The average distance between adjacent structures and renal cell carcinomas before displacement was 0.36 cm (range, 0.1-1.0 cm). The average distance between structures and adjacent renal cell carcinomas after displacement was 1.94 cm (range, 1.1-4.3 cm) (p < 0.0001). The average volume of D5W used to achieve organ displacement was 273.5 mL. No complications were associated with this technique. CT-guided injection of D5W into the retroperitoneum is an effective method for displacing vital structures away from renal cell carcinoma.

  12. Testing Metal-Poor Stellar Models and Isochrones with HST Parallaxes of Metal-Poor Stars

    NASA Astrophysics Data System (ADS)

    Chaboyer, B.; McArthur, B. E.; O'Malley, E.; Benedict, G. F.; Feiden, G. A.; Harrison, T. E.; McWilliam, A.; Nelan, E. P.; Patterson, R. J.; Sarajedini, A.

    2017-02-01

    Hubble Space Telescope (HST) fine guidance sensor observations were used to obtain parallaxes of eight metal-poor ([Fe/H] < -1.4) stars. The parallaxes of these stars determined by the new Hipparcos reduction average 17% accuracy, in contrast to our new HST parallaxes, which average 1% accuracy and have errors on the individual parallaxes ranging from 85 to 144 μas. These parallax data were combined with HST Advanced Camera for Surveys photometry in the F606W and F814W filters to obtain the absolute magnitudes of the stars with an accuracy of 0.02-0.03 mag. Six of these stars are on the main sequence (MS) (with -2.7 < [Fe/H] < -1.8) and are suitable for testing metal-poor stellar evolution models and determining the distances to metal-poor globular clusters (GCs). Using the abundances obtained by O’Malley et al., we find that standard stellar models using the VandenBerg & Clem color transformation do a reasonable job of matching five of the MS stars, with HD 54639 ([Fe/H] = -2.5) being anomalous in its location in the color-magnitude diagram. Stellar models and isochrones were generated using a Monte Carlo analysis to take into account uncertainties in the models. Isochrones that fit the parallax stars were used to determine the distances and ages of nine GCs (with -2.4 ≤ [Fe/H] ≤ -1.9). Averaging together the age of all nine clusters led to an absolute age of the oldest, most metal-poor GCs of 12.7 ± 1.0 Gyr, where the quoted uncertainty takes into account the known uncertainties in the stellar models and isochrones, along with the uncertainty in the distance and reddening of the clusters.

  13. Inferring properties of disordered chains from FRET transfer efficiencies

    NASA Astrophysics Data System (ADS)

    Zheng, Wenwei; Zerze, Gül H.; Borgia, Alessandro; Mittal, Jeetain; Schuler, Benjamin; Best, Robert B.

    2018-03-01

    Förster resonance energy transfer (FRET) is a powerful tool for elucidating both structural and dynamic properties of unfolded or disordered biomolecules, especially in single-molecule experiments. However, the key observables, namely, the mean transfer efficiency and fluorescence lifetimes of the donor and acceptor chromophores, are averaged over a broad distribution of donor-acceptor distances. The inferred average properties of the ensemble therefore depend on the form of the model distribution chosen to describe the distance, as has been widely recognized. In addition, while the distribution for one type of polymer model may be appropriate for a chain under a given set of physico-chemical conditions, it may not be suitable for the same chain in a different environment so that even an apparently consistent application of the same model over all conditions may distort the apparent changes in chain dimensions with variation of temperature or solution composition. Here, we present an alternative and straightforward approach to determining ensemble properties from FRET data, in which the polymer scaling exponent is allowed to vary with solution conditions. In its simplest form, it requires either the mean FRET efficiency or fluorescence lifetime information. In order to test the accuracy of the method, we have utilized both synthetic FRET data from implicit and explicit solvent simulations for 30 different protein sequences, and experimental single-molecule FRET data for an intrinsically disordered and a denatured protein. In all cases, we find that the inferred radii of gyration are within 10% of the true values, thus providing higher accuracy than simpler polymer models. In addition, the scaling exponents obtained by our procedure are in good agreement with those determined directly from the molecular ensemble. Our approach can in principle be generalized to treating other ensemble-averaged functions of intramolecular distances from experimental data.

  14. Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs.

    PubMed

    Cunningham, Daniel J; Shearer, David A; Carter, Neil; Drawer, Scott; Pollard, Ben; Bennett, Mark; Eager, Robin; Cook, Christian J; Farrell, John; Russell, Mark; Kilduff, Liam P

    2018-01-01

    The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5-40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. Accordingly, this study compared rolling average (ROLL) and fixed-time (FIXED) epochs for quantifying the peak movement demands of international rugby union match-play as a function of playing position. Elite players from three different squads (n = 119) were monitored using 10 Hz GPS during 36 matches played in the 2014-2017 seasons. Players categorised broadly as forwards and backs, and then by positional sub-group (FR: front row, SR: second row, BR: back row, HB: half back, MF: midfield, B3: back three) were monitored during match-play for peak values of high-speed running (>5 m·s-1; HSR) and relative distance covered (m·min-1) over 60-300 s using two types of sample-epoch (ROLL, FIXED). Irrespective of the method used, as the epoch length increased, values for the intensity of running actions decreased (e.g., For the backs using the ROLL method, distance covered decreased from 177.4 ± 20.6 m·min-1 in the 60 s epoch to 107.5 ± 13.3 m·min-1 for the 300 s epoch). For the team as a whole, and irrespective of position, estimates of fixed effects indicated significant between-method differences across all time-points for both relative distance covered and HSR. Movement demands were underestimated consistently by FIXED versus ROLL with differences being most pronounced using 60 s epochs (95% CI HSR: -6.05 to -4.70 m·min-1, 95% CI distance: -18.45 to -16.43 m·min-1). For all HSR time epochs except one, all backs groups increased more (p < 0.01) from FIXED to ROLL than the forward groups. Linear mixed modelling of ROLL data highlighted that for HSR (except 60 s epoch), SR was the only group not significantly different to FR. For relative distance covered all other position groups were greater than the FR (p < 0.05). The FIXED method underestimated both relative distance (~11%) and HSR values (up to ~20%) compared to the ROLL method. These differences were exaggerated for the HSR variable in the backs position who covered the greatest HSR distance; highlighting important consideration for those implementing the FIXED method of analysis. The data provides coaches with a worst-case scenario reference on the running demands required for periods of 60-300 s in length. This information offers novel insight into game demands and can be used to inform the design of training games to increase specificity of preparation for the most demanding phases of matches.

  15. Resolving the Discrepancy of Distance to M60, a Giant Elliptical Galaxy in Virgo

    NASA Astrophysics Data System (ADS)

    Lee, Myung Gyoon; Jang, In Sung

    2017-05-01

    There is a well-known discrepancy in the distance estimation of M60, a giant elliptical galaxy in Virgo; the planetary nebula luminosity function (PNLF) distance moduli for this galaxy are, on average, 0.4 mag smaller than the values based on the surface brightness fluctuation (SBF) in the literature. We present photometry of the resolved stars in an outer field of M60 based on deep F775W and F850LP images in the Hubble Space Telescope obtained as part of the Pure Parallel Program in the archive. Detected stars are mostly old red giants in the halo of M60. With this photometry, we determine a distance to M60 using the tip of the red giant branch (TRGB). A TRGB is detected at F850LP{}{TRGB}=26.70+/- 0.06 mag, in the luminosity function of the red giants. This value corresponds to F814W{}0,{TRGB}=27.13+/- 0.06 mag and {{QT}}{TRGB}=27.04+/- 0.07 mag, where QT is a color-corrected F814W magnitude. From this we derive a distance modulus, {(m-M)}0=31.05+/- 0.07({ran}) +/- 0.06({sys}) (d=16.23+/- 0.50({ran})+/- 0.42({sys}) Mpc). This value is 0.3 mag larger than the PNLF distances and 0.1 mag smaller than the SBF distances in the previous studies, which indicates that the PNLF distances to M60 reported in the literature have larger uncertainties than the suggested values.

  16. Comparing Global Positioning System (GPS) and Global Navigation Satellite System (GNSS) Measures of Team Sport Movements.

    PubMed

    Jackson, Benjamin M; Polglaze, Ted; Dawson, Brian; King, Trish; Peeling, Peter

    2018-02-21

    To compare data from conventional GPS and new GNSS-enabled tracking devices, and to examine the inter-unit reliability of GNSS devices. Inter-device differences between 10 Hz GPS and GNSS devices were examined during laps (n=40) of a simulated game circuit (SGC) and during elite hockey matches (n=21); GNSS inter-unit reliability was also examined during the SGC laps. Differences in distance values and measures in three velocity categories (low <3 m.s -1 ; moderate 3-5 m.s -1 ; high >5 m.s -1 ) and acceleration/deceleration counts (>1.46 m.s -2 and < -1.46 m.s -2 ) were examined using one-way ANOVA. Inter-unit GNSS reliability was examined using the coefficient of variation (CV) and intra-class correlation coefficient (ICC). Inter-device differences (P <0.05) were found for measures of peak deceleration, low-speed distance, % total distance at low speed, and deceleration count during the SGC, and for all measures except total distance and low-speed distance during hockey matches. Inter-unit (GNSS) differences (P <0.05) were not found. The CV was below 5% for total distance, average and peak speeds and distance and % total distance of low-speed running. The GNSS devices had a lower HDoP score than GPS devices in all conditions. These findings suggest that GNSS devices may be more sensitive than GPS in quantifying the physical demands of team sport movements, but further study into the accuracy of GNSS devices is required.

  17. Using Genealogical Mapping and Genetic Neighborhood Sizes to Quantify Dispersal Distances in the Neotropical Passerine, the Black-Capped Vireo

    PubMed Central

    Athrey, Giridhar; Lance, Richard F.; Leberg, Paul L.

    2015-01-01

    Dispersal is a key demographic process, ultimately responsible for genetic connectivity among populations. Despite its importance, quantifying dispersal within and between populations has proven difficult for many taxa. Even in passerines, which are among the most intensely studied, individual movement and its relation to gene flow remains poorly understood. In this study we used two parallel genetic approaches to quantify natal dispersal distances in a Neotropical migratory passerine, the black-capped vireo. First, we employed a strategy of sampling evenly across the landscape coupled with parentage assignment to map the genealogical relationships of individuals across the landscape, and estimate dispersal distances; next, we calculated Wright’s neighborhood size to estimate gene dispersal distances. We found that a high percentage of captured individuals were assigned at short distances within the natal population, and males were assigned to the natal population more often than females, confirming sex-biased dispersal. Parentage-based dispersal estimates averaged 2400m, whereas gene dispersal estimates indicated dispersal distances ranging from 1600–4200 m. Our study was successful in quantifying natal dispersal distances, linking individual movement to gene dispersal distances, while also providing a detailed look into the dispersal biology of Neotropical passerines. The high-resolution information was obtained with much reduced effort (sampling only 20% of breeding population) compared to mark-resight approaches, demonstrating the potential applicability of parentage-based approaches for quantifying dispersal in other vagile passerine species. PMID:26461257

  18. Application of agglomerative clustering for analyzing phylogenetically on bacterium of saliva

    NASA Astrophysics Data System (ADS)

    Bustamam, A.; Fitria, I.; Umam, K.

    2017-07-01

    Analyzing population of Streptococcus bacteria is important since these species can cause dental caries, periodontal, halitosis (bad breath) and more problems. This paper will discuss the phylogenetically relation between the bacterium Streptococcus in saliva using a phylogenetic tree of agglomerative clustering methods. Starting with the bacterium Streptococcus DNA sequence obtained from the GenBank, then performed characteristic extraction of DNA sequences. The characteristic extraction result is matrix form, then performed normalization using min-max normalization and calculate genetic distance using Manhattan distance. Agglomerative clustering technique consisting of single linkage, complete linkage and average linkage. In this agglomerative algorithm number of group is started with the number of individual species. The most similar species is grouped until the similarity decreases and then formed a single group. Results of grouping is a phylogenetic tree and branches that join an established level of distance, that the smaller the distance the more the similarity of the larger species implementation is using R, an open source program.

  19. Impact of long-range interactions on the disordered vortex lattice

    NASA Astrophysics Data System (ADS)

    Koopmann, J. A.; Geshkenbein, V. B.; Blatter, G.

    2003-07-01

    The interaction between the vortex lines in a type-II superconductor is mediated by currents. In the absence of transverse screening this interaction is long ranged, stiffening up the vortex lattice as expressed by the dispersive elastic moduli. The effect of disorder is strongly reduced, resulting in a mean-squared displacement correlator ≡<[u(R,L)-u(0,0)]2> characterized by a mere logarithmic growth with distance. Finite screening cuts the interaction on the scale of the London penetration depth λ and limits the above behavior to distances R<λ. Using a functional renormalization-group approach, we derive the flow equation for the disorder correlation function and calculate the disorder-averaged mean-squared relative displacement ∝ ln2σ(R/a0). The logarithmic growth (2σ=1) in the perturbative regime at small distances [A. I. Larkin and Yu. N. Ovchinnikov, J. Low Temp. Phys. 34, 409 (1979)] crosses over to a sub-logarithmic growth with 2σ=0.348 at large distances.

  20. Thirty-Second Walk Test: Expansion of Normative Data.

    PubMed

    Lieberstein, Michael; Weingarten, Goldie; Vialu, Carlo; Itzkowitz, Adina; Doyle, Maura; Covino, Frank; Kaplan, Sandra L

    2018-01-01

    To collect 30-second walk test (30sWT) normative data on a large, diverse sample of school children developing typically, ages 5 to 13 years, and describe the influences of gender, body mass index, and path shape on distance walked. Five physical therapists administered the 30sWT on 1223 children developing typically (boys = 517, girls = 706) from 20 urban schools. Average distances (standard deviation) ranged from 139.1 (20.3) to 163.0 (18.6) ft; children aged 10 years walked the farthest and those aged 5 years the shortest. Distance steadily increased from ages 5 to 10 years, steadily decreased from ages 11 to 13 years; children aged 8, 9, and 10 years had statistical but not functionally meaningful gender differences. Body mass index and path shape had no meaningful effects. Distance and velocities are similar to prior studies. This study updated 30sWT normative values with a large, ethnically diverse, urban sample developing typically. Norms may be useful as part of a comprehensive examination.

  1. Structural, morphological and mechanical properties of niobium nitride thin films grown by ion and electron beams emanated from plasma

    NASA Astrophysics Data System (ADS)

    Siddiqui, Jamil; Hussain, Tousif; Ahmad, Riaz; Umar, Zeeshan A.; Abdus Samad, Ubair

    2016-05-01

    The influence of variation in plasma deposition parameters on the structural, morphological and mechanical characteristics of the niobium nitride films grown by plasma-emanated ion and electron beams are investigated. Crystallographic investigation made by X-ray diffractometer shows that the film synthesized at 10 cm axial distance with 15 plasma focus shots (PFS) exhibits better crystallinity when compared to the other deposition conditions. Morphological analysis made by scanning electron microscope reveals a definite granular pattern composed of homogeneously distributed nano-spheroids grown as clustered particles for the film synthesized at 10 cm axial distance for 15 PFS. Roughness analysis demonstrates higher rms roughness for the films synthesized at shorter axial distance and by greater number of PFS. Maximum niobium atomic percentage (35.8) and maximum average hardness (19.4 ± 0.4 GPa) characterized by energy-dispersive spectroscopy and nano-hardness analyzer respectively are observed for film synthesized at 10 cm axial distance with 15 PFS.

  2. Which similarity measure is better for analyzing protein structures in a molecular dynamics trajectory?

    PubMed

    Cossio, Pilar; Laio, Alessandro; Pietrucci, Fabio

    2011-06-14

    An important step in the computer simulation of the dynamics of biomolecules is the comparison of structures in a trajectory by exploiting a measure of distance. This allows distinguishing structures which are geometrically similar from those which are different. By analyzing microseconds-long all-atom molecular dynamics simulations of a polypeptide, we find that a distance based on backbone dihedral angles performs very well in distinguishing structures that are kinetically correlated from those that are not, while the widely used C(α) root mean square distance performs more poorly. The root mean square difference between contact matrices turns out instead to be the metric providing the highest clustering coefficient, namely, according to this similarity measure, the neighbors of a structure are also, on average, neighbors among themselves. We also propose a combined distance measure which, for the system considered here, performs well both for distinguishing structures which are distant in time and for giving a consistent cluster analysis. This journal is © the Owner Societies 2011

  3. Influence of the effective lens position, as predicted by axial length and keratometry, on the near add power of multifocal intraocular lenses.

    PubMed

    Savini, Giacomo; Hoffer, Kenneth J; Lombardo, Marco; Serrao, Sebastiano; Schiano-Lomoriello, Domenico; Ducoli, Pietro

    2016-01-01

    To calculate the near focal distance of different multifocal intraocular lenses (IOLs) as a function of the 2 parameters that are measured before cataract surgery; that is, axial length (AL) and refractive corneal power (keratometry [K]). GB Bietti Foundation IRCCS, Rome, Italy. Noninterventional theoretical study. The IOL power for emmetropia was first calculated in an eye model with the AL ranging from 20 to 30 mm and K from 38 to 48 diopters (D). Then, the predicted myopic refraction for any given IOL add power (from +1.5 to +4.0 D) was calculated, and from this value the near focal distance was obtained. Calculations were also performed for the average eye (K = 43.81 D; AL = 23.65 mm). The near focal distance increased with increasing values of K and AL for each near power add. The near focal distance ranged between 53 cm and 72 cm (21 inches and 28 inches) for a multifocal IOL with +2.50 D, between 44 cm and 60 cm (17 inches and 24 inches) for a multifocal IOL with +3.00 D add, and between 33 cm and 44 cm (13 inches and 18 inches) for a multifocal IOL with +4.00 D add. In the average eye, the near focal distance ranges between 36 cm (near add power = 4.00 D) and 99 cm (near add power = 1.5 D). Longer eyes with steeper corneas showed the longest near focal distance and could experience more difficulties in focusing near objects after surgery. The opposite was true for short hyperopic eyes. Dr. Hoffer receives licensing fees for the commercial use of the registered trademark Hoffer from all biometry manufacturers using the Hoffer Q formula to ensure that it is programmed correctly and book royalties from Slack, Inc., for the textbook IOL Power. None of the authors has a financial or proprietary interest in any material or method mentioned. Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  4. Social dynamics in emergency evacuations: Disentangling crowd's attraction and repulsion effects

    NASA Astrophysics Data System (ADS)

    Haghani, Milad; Sarvi, Majid

    2017-06-01

    The social dynamics of crowds in emergency escape scenarios have been conventionally modelled as the net effect of virtual forces exerted by the crowd on each individual (as self-driven particles), with the magnitude of the influence formulated as decreasing functions of inter-individual distances and the direction of effect assumed to be transitioning from repulsion to attraction by distance. Here, we revisit this conventional assumption using laboratory experimental data. We show based on robust econometric hypothesis-testing methods that individuals' perception of other escapees differs based on whether those individuals are jamming around exit destinations or are on the move towards the destinations. Also, for moving crowds, it differs based on whether the escape destination chosen by the moving flow is visible or invisible to the individual. The presence of crowd jams around a destination, also the movement of crowd flows towards visible destinations are both perceived on average as repulsion (or disutility) effects (with the former showing significantly larger magnitude than the latter). The movement of crowd flows towards an invisible destination, however, is on average perceived as attraction (or utility) effect. Yet, further hypothesis testing showed that neither of those effects in isolation determines adequately whether an individual would merge with or diverge from the crowd. Rather, the social interaction factors act (at significant levels) in conjunction with the physical factors of the environments (including spatial distances to exit destinations and destinations' visibility). In brief, our finding disentangles the conditions under which individuals are more likely to show mass behaviour from the situations where they are more likely to break from the herd. It identifies two factors that moderate the perception of social interactions, ;crowds' jam/movement status; and ;environmental setup;. Our results particularly challenge the taxonomy of attraction-repulsion social interaction forces defined purely based on the distance of the individual to the surrounding crowd, by showing that crowds could be in far distance and yet be perceived as repulsion effect, or they could be in close distance and yet act as attraction effect.

  5. Contouring variability of human- and deformable-generated contours in radiotherapy for prostate cancer

    NASA Astrophysics Data System (ADS)

    Gardner, Stephen J.; Wen, Ning; Kim, Jinkoo; Liu, Chang; Pradhan, Deepak; Aref, Ibrahim; Cattaneo, Richard, II; Vance, Sean; Movsas, Benjamin; Chetty, Indrin J.; Elshaikh, Mohamed A.

    2015-06-01

    This study was designed to evaluate contouring variability of human-and deformable-generated contours on planning CT (PCT) and CBCT for ten patients with low-or intermediate-risk prostate cancer. For each patient in this study, five radiation oncologists contoured the prostate, bladder, and rectum, on one PCT dataset and five CBCT datasets. Consensus contours were generated using the STAPLE method in the CERR software package. Observer contours were compared to consensus contour, and contour metrics (Dice coefficient, Hausdorff distance, Contour Distance, Center-of-Mass [COM] Deviation) were calculated. In addition, the first day CBCT was registered to subsequent CBCT fractions (CBCTn: CBCT2-CBCT5) via B-spline Deformable Image Registration (DIR). Contours were transferred from CBCT1 to CBCTn via the deformation field, and contour metrics were calculated through comparison with consensus contours generated from human contour set. The average contour metrics for prostate contours on PCT and CBCT were as follows: Dice coefficient—0.892 (PCT), 0.872 (CBCT-Human), 0.824 (CBCT-Deformed); Hausdorff distance—4.75 mm (PCT), 5.22 mm (CBCT-Human), 5.94 mm (CBCT-Deformed); Contour Distance (overall contour)—1.41 mm (PCT), 1.66 mm (CBCT-Human), 2.30 mm (CBCT-Deformed); COM Deviation—2.01 mm (PCT), 2.78 mm (CBCT-Human), 3.45 mm (CBCT-Deformed). For human contours on PCT and CBCT, the difference in average Dice coefficient between PCT and CBCT (approx. 2%) and Hausdorff distance (approx. 0.5 mm) was small compared to the variation between observers for each patient (standard deviation in Dice coefficient of 5% and Hausdorff distance of 2.0 mm). However, additional contouring variation was found for the deformable-generated contours (approximately 5.0% decrease in Dice coefficient and 0.7 mm increase in Hausdorff distance relative to human-generated contours on CBCT). Though deformable contours provide a reasonable starting point for contouring on CBCT, we conclude that contours generated with B-Spline DIR require physician review and editing if they are to be used in the clinic.

  6. 42 CFR 456.522 - Content of request for variance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Review Plans: FFP, Waivers, and Variances for Hospitals and Mental Hospitals Ur Plan: Remote Facility Variances from Time..., mental hospital, and ICF located within a 50-mile radius of the facility; (e) The distance and average...

  7. Flare angles measured with ball gage

    NASA Technical Reports Server (NTRS)

    Cleghorn, D.; Wall, W. A.

    1968-01-01

    Precision tungsten carbide balls measure the internal angle of flared joints. Measurements from small and large balls in the flare throat to an external reference point are made. The difference in distances and diameters determine the average slope of the flare between the points of ball contact.

  8. 49 CFR 523.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... a functioning vehicle that has the primary load carrying device or container (or equivalent... the product of track width (measured in inches, calculated as the average of front and rear track.... For purposes of this definition, track width is the lateral distance between the centerlines of the...

  9. Distribution of Mercury Concentrations in Tree Rings and Surface Soils Adjacent to a Phosphate Fertilizer Plant in Southern Korea.

    PubMed

    Jung, Raae; Ahn, Young Sang

    2017-08-01

    This study aimed to determine mercury concentrations in tree rings and surface soils at distances of 4, 26 and 40 km from a fertilizer plant located in Yeosu City, Korea. Mercury concentrations in all tree rings were low prior to the establishment of the plant in 1977 and became elevated thereafter. The highest average mercury concentration in the tree rings was 11.96 ng g -1 at the Yeosu site located nearest to the plant, with the lowest average mercury concentration of 4.45 ng g -1 at the Suncheon site furthest away from the plant. In addition, the highest mercury content in the surface soil was 108.51 ng cm -3 at the Yeosu site, whereas the lowest mercury content in the surface soil was 31.47 ng cm -3 at the Suncheon site. The mercury levels decreased gradually with increasing distance from the plant.

  10. Study on Strata Behavior Regularity of 1301 Face in Thick Bedrock of Wei - qiang Coal Mine

    NASA Astrophysics Data System (ADS)

    Gu, Shuancheng; Yao, Boyu

    2017-09-01

    In order to ensure the safe and efficient production of the thick bedrock face, the rule of the strata behavior of the thick bedrock face is discussed through the observation of the strata pressure of the 1301 first mining face in Wei qiang coal mine. The initial face is to press the average distance of 50.75m, the periodic weighting is to press the average distance of 12.1m; during the normal mining period, although the upper roof can not be broken at the same time, but the pressure step is basically the same; the working face for the first weighting and periodical weighting is more obvious to the change of pressure step change, when the pressure of the working face is coming, the stent force increased significantly, but there are still part of the stent work resistance exceeds the rated working resistance, low stability, still need to strengthen management.

  11. Horizontal alignment of 5' -> 3' intergene distance segment tropy with respect to the gene as the conserved basis for DNA transcription.

    PubMed

    Sarin, Hemant

    2017-03-01

    To study the conserved basis for gene expression in comparative cell types at opposite ends of the cell pressuromodulation spectrum, the lymphatic endothelial cell and the blood microvascular capillary endothelial cell. The mechanism for gene expression is studied in terms of the 5' -> 3' direction paired point tropy quotients ( prpT Q s) and the final 5' -> 3' direction episodic sub-episode block sums split-integrated weighted average-averaged gene overexpression tropy quotient ( esebssiwaagoT Q ). The final 5' -> 3' esebssiwaagoT Q classifies an lymphatic endothelial cell overexpressed gene as a supra-pressuromodulated gene ( esebssiwaagoT Q ≥ 0.25 < 0.75) every time and classifies a blood microvascular capillary endothelial cell overexpressed gene every time as an infra-pressuromodulated gene ( esebssiwaagoT Q < 0.25) (100% sensitivity; 100% specificity). Horizontal alignment of 5' -> 3' intergene distance segment tropy wrt the gene is the basis for DNA transcription in the pressuromodulated state.

  12. Performance Analysis of Classification Methods for Indoor Localization in Vlc Networks

    NASA Astrophysics Data System (ADS)

    Sánchez-Rodríguez, D.; Alonso-González, I.; Sánchez-Medina, J.; Ley-Bosch, C.; Díaz-Vilariño, L.

    2017-09-01

    Indoor localization has gained considerable attention over the past decade because of the emergence of numerous location-aware services. Research works have been proposed on solving this problem by using wireless networks. Nevertheless, there is still much room for improvement in the quality of the proposed classification models. In the last years, the emergence of Visible Light Communication (VLC) brings a brand new approach to high quality indoor positioning. Among its advantages, this new technology is immune to electromagnetic interference and has the advantage of having a smaller variance of received signal power compared to RF based technologies. In this paper, a performance analysis of seventeen machine leaning classifiers for indoor localization in VLC networks is carried out. The analysis is accomplished in terms of accuracy, average distance error, computational cost, training size, precision and recall measurements. Results show that most of classifiers harvest an accuracy above 90 %. The best tested classifier yielded a 99.0 % accuracy, with an average error distance of 0.3 centimetres.

  13. Scaling and entropy in p-median facility location along a line

    NASA Astrophysics Data System (ADS)

    Gastner, Michael T.

    2011-09-01

    The p-median problem is a common model for optimal facility location. The task is to place p facilities (e.g., warehouses or schools) in a heterogeneously populated space such that the average distance from a person's home to the nearest facility is minimized. Here we study the special case where the population lives along a line (e.g., a road or a river). If facilities are optimally placed, the length of the line segment served by a facility is inversely proportional to the square root of the population density. This scaling law is derived analytically and confirmed for concrete numerical examples of three US interstate highways and the Mississippi River. If facility locations are permitted to deviate from the optimum, the number of possible solutions increases dramatically. Using Monte Carlo simulations, we compute how scaling is affected by an increase in the average distance to the nearest facility. We find that the scaling exponents change and are most sensitive near the optimum facility distribution.

  14. Principal components technique analysis for vegetation and land use discrimination. [Brazilian cerrados

    NASA Technical Reports Server (NTRS)

    Parada, N. D. J. (Principal Investigator); Formaggio, A. R.; Dossantos, J. R.; Dias, L. A. V.

    1984-01-01

    Automatic pre-processing technique called Principal Components (PRINCO) in analyzing LANDSAT digitized data, for land use and vegetation cover, on the Brazilian cerrados was evaluated. The chosen pilot area, 223/67 of MSS/LANDSAT 3, was classified on a GE Image-100 System, through a maximum-likehood algorithm (MAXVER). The same procedure was applied to the PRINCO treated image. PRINCO consists of a linear transformation performed on the original bands, in order to eliminate the information redundancy of the LANDSAT channels. After PRINCO only two channels were used thus reducing computer effort. The original channels and the PRINCO channels grey levels for the five identified classes (grassland, "cerrado", burned areas, anthropic areas, and gallery forest) were obtained through the MAXVER algorithm. This algorithm also presented the average performance for both cases. In order to evaluate the results, the Jeffreys-Matusita distance (JM-distance) between classes was computed. The classification matrix, obtained through MAXVER, after a PRINCO pre-processing, showed approximately the same average performance in the classes separability.

  15. Language distance and tree reconstruction

    NASA Astrophysics Data System (ADS)

    Petroni, Filippo; Serva, Maurizio

    2008-08-01

    Languages evolve over time according to a process in which reproduction, mutation and extinction are all possible. This is very similar to haploid evolution for asexual organisms and for the mitochondrial DNA of complex ones. Exploiting this similarity, it is possible, in principle, to verify hypotheses concerning the relationship among languages and to reconstruct their family tree. The key point is the definition of the distances among pairs of languages in analogy with the genetic distances among pairs of organisms. Distances can be evaluated by comparing grammar and/or vocabulary, but while it is difficult, if not impossible, to quantify grammar distance, it is possible to measure a distance from vocabulary differences. The method used by glottochronology computes distances from the percentage of shared 'cognates', which are words with a common historical origin. The weak point of this method is that subjective judgment plays a significant role. Here we define the distance of two languages by considering a renormalized edit distance among words with the same meaning and averaging over the two hundred words contained in a Swadesh list. In our approach the vocabulary of a language is the analogue of DNA for organisms. The advantage is that we avoid subjectivity and, furthermore, reproducibility of results is guaranteed. We apply our method to the Indo-European and the Austronesian groups, considering, in both cases, fifty different languages. The two trees obtained are, in many respects, similar to those found by glottochronologists, with some important differences as regards the positions of a few languages. In order to support these different results we separately analyze the structure of the distances of these languages with respect to all the others.

  16. Effects of the distance among multiple spreaders on the spreading

    NASA Astrophysics Data System (ADS)

    Hu, Z.-L.; Liu, J.-G.; Yang, G.-Y.; Ren, Z.-M.

    2014-04-01

    It is very important to investigate the multiple spreaders' effects since the spreading phenomenon is ubiquitous in many complex systems. In this letter, we investigate the effects of the distance among the initial multiple spreaders for regular networks and WS (Watts-Strogatz) small-world networks based on the SIR (Susceptible-Infected-Recovered) model. Assuming the epidemics can spread over the network, the theoretical and experimental results show that for regular networks the larger the distance between spreaders is, the more effective the spreading is. For WS networks, the spreading efficiency will decrease when the distance exceeds a certain value, and a larger connection probability and average degree will result in a smaller distance of the most effective spreading. A better spreading strategy using n spreaders is to choose either the highest k or ks nodes with the condition that there are not any pairs of the n spreaders linked directly (Kitsak M. et al., Nat. Phys., 6 (2010) 888). However, we find that the spreading will be more effective when the distances among the largest-degree spreaders increase. All these results are independent of the network size for the two initial spreaders case. This work may give new insights to explore more effective methods to inhibit the epidemic spreading or increase the information diffusion.

  17. Geometric effects resulting from the asymmetry of dipping fault: Hanging wall/ footwall effects

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Xie, Li-Li; Hu, Jin-Jun

    2008-05-01

    Root-mean-square distance D rms with characteristic of weighted-average is introduced in this article firstly. D rms can be used to capture the general proximity of a site to a dipping fault plane comparing with the rupture distance D rup and the seismogenic distance D seis. Then, using D rup, D seis and D rms, the hanging wall/footwall effects on the peak ground acceleration (PGA) during the 1999 Chi-Chi earthquake are evaluated by regression analysis. The logarithm residual shows that the PGA on hanging wall is much greater than that on footwall at the same D rup or D seis when the D rup or D seis is used as site-to-source distance measure. In contrast, there is no significant difference between the PGA on hanging wall and that on footwall at the same D rms when D rms is used. This result confirms that the hanging wall/footwall effect is mainly a geometric effect caused by the asymmetry of dipping fault. Therefore, the hanging wall/footwall effect on the near-fault ground motions can be ignored in the future attenuation analysis if the root-mean-square distance D rms is used as the site-to-source distance measure.

  18. Comparison of geographic methods to assess travel patterns of persons diagnosed with HIV in Philadelphia: how close is close enough?

    PubMed

    Eberhart, Michael G; Share, Amanda M; Shpaner, Mark; Brady, Kathleen A

    2015-02-01

    Travel distance to medical care has been assessed using a variety of geographic methods. Network analyses are less common, but may generate more accurate estimates of travel costs. We compared straight-line distances and driving distance, as well as average drive time and travel time on a public transit network for 1789 persons diagnosed with HIV between 2010 and 2012 to identify differences overall, and by distinct geographic areas of Philadelphia. Paired t-tests were used to assess differences across methods, and analysis of variance was used to assess between-group differences. Driving distances were significantly longer than straight-line distances (p<0.001) and transit times were significantly longer than driving times (p<0.001). Persons living in the northeast section of the city traveled greater distances, and at greater cost of time and effort, than persons in all other areas of the city (p<0.001). Persons living in the northwest section of the city traveled farther and longer than all other areas except the northeast (p<0.0001). Network analyses that include public transit will likely produce a more realistic estimate of the travel costs, and may improve models to predict medical care outcomes. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. SU-E-J-85: The Effect of Different Imaging Modalities On the Delineation of the True Spinal Cord for Spinal Stereotactic Body Radiation Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goddard, L; Brodin, P; Mani, K

    Purpose: SBRT allows the delivery of high dose radiation treatments to localized tumors while minimizing dose to surrounding tissues. Due to the large doses delivered, accurate contouring of organs at risk is essential. In this study, differences between the true spinal cord as seen using MRI and CT myelogram (CTM) have been assessed in patients with spinal metastases treated using SBRT. Methods: Ten patients were identified that have both a CTM and a MRI. Using rigid registration tools, the MRI was fused to the CTM. The thecal sac and true cord were contoured using each imaging modality. Images were exportedmore » and analyzed for similarity by computing the Dice similarity coefficient and the modified Hausdorff distance (greatest distance from a point in one set to the closest point in the other set). Results: The Dice coefficient was calculated for the thecal sac (0.81 ±0.06) and true cord (0.63 ±0.13). These two measures are correlated; however, some points show a low true cord overlap despite a high overlap for the thecal sac. The Hausdorff distance for structure comparisons was also calculated. For thecal sac structures, the average value, 1.6mm (±1.1), indicates good overlap. For true cord comparison, the average value, 0.3mm (±0.16), indicates very good overlap. The minimum Hausdorff distance between the true cord and thecal sac was on average 1.6mm (±0.9) Conclusion: The true cord position as seen in MRI and CTM is fairly constant, although care should be taken as large differences can be seen in individual patients. Avoidning the true cord in spine SBRT is critical, so the ability to visualize the true cord before performing SBRT to the vertebrae is essential. Here, CT myelogram appears an excellent, robust option, that can be obtained the day of treatment planning and is unaffected by uncertainties in image fusion.« less

  20. [Spatial patterns and influence factors of specialization in tea cultivation based on geographically weighted regression model: A case study of Anxi County of Fujian Province, China].

    PubMed

    Shui, Wei; DU, Yong; Chen, Yi Ping; Jian, Xiao Mei; Fan, Bing Xiong

    2017-04-18

    Anxi County, specializing in tea cultivation, was taken as a case in this research. Pearson correlation analysis, ordinary least squares model (OLS) and geographically weighted regression model (GWR) were used to select four primary influence factors of specialization in tea cultivation (i.e., the average elevation, net income per capita, proportion of agricultural population, and the distance from roads) by analyzing the specialization degree of each town of Anxi County. Meanwhile, the spatial patterns of specialization in tea cultivation of Anxi County were evaluated. The results indicated that specialization in tea cultivation of Anxi County showed an obvious spatial auto-correlation, and a spatial pattern with "low-middle-high" circle structure, which was similar to Von Thünen's circle structure model, appeared from the county town to its surrounding region. Meanwhile, GWR (0.624) had a better fitting degree than OLS (0.595), and GWR could reasonably expound the spatial data. Contrary to the agricultural location theory of Von Thünen's model, which indicated that distance from market was a determination factor, the specialization degree of tea cultivation in Anxi was mainly decided by natural conditions of mountain area, instead of the social factors. Specialization degree of tea cultivation was positively correlated with the average elevation, net income per capita and the proportion of agricultural population, while a negative correlation was found between the distance from roads and specialization degree of tea cultivation. Coefficients of regression between the specialization degree of tea cultivation and two factors (i.e., the average elevation and net income per capita) showed a spatial pattern of higher level in the north direction and lower level in the south direction. On the contrary, the regression coefficients for the proportion of agricultural population increased from south to north of Anxi County. Furthermore, regression coefficient for the distance from roads showed a spatial pattern of higher level in the northeast direction and lower level in the southwest direction of Anxi County.

  1. Copper vapor laser acoustic thermometry system

    DOEpatents

    Galkowski, Joseph J.

    1987-01-01

    A copper vapor laser (CVL) acoustic thermometry system is disclosed. The invention couples an acoustic pulse a predetermined distance into a laser tube by means of a transducer and an alumina rod such that an echo pulse is returned along the alumina rod to the point of entry. The time differential between the point of entry of the acoustic pulse into the laser tube and the exit of the echo pulse is related to the temperature at the predetermined distance within the laser tube. This information is processed and can provide an accurate indication of the average temperature within the laser tube.

  2. Modeling and control parameters for GMAW, short-circuiting transfer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cook, G.E.; DeLapp, D.R.; Barnett, R.J.

    1996-12-31

    Digital signal processing was used to analyze the electrical arc signals of the gas metal arc welding process with short-circuiting transfer. Among the features extracted were arc voltage and current (both average and peak values), short-circuiting frequency, arc period, shorting period, and the ratio of the arcing to shorting period. Additionally , a Joule heating model was derived which accurately predicted the melt-back distance during each short. The short-circuiting frequency, the ratio of the arc period to short periods, and the melt-back distance were found to be good indicators for monitoring and control of stable arc conditions.

  3. Further We Travel the Faster We Go.

    PubMed

    Varga, Levente; Kovács, András; Tóth, Géza; Papp, István; Néda, Zoltán

    2016-01-01

    The average travelling speed increases in a nontrivial manner with the travel distance. This leads to scaling-like relations on quite extended spatial scales, for all mobility modes taken together and also for a given mobility mode in part. We offer a wide range of experimental results, investigating and quantifying this universal effect and its measurable causes. The increasing travelling speed with the travel distance arises from the combined effects of: choosing the most appropriate travelling mode; the structure of the travel networks; the travel times lost in the main hubs, starting or target cities; and the speed limit of roads and vehicles.

  4. Evidence for a novel chemisorption bond: Formate (HCO/sub 2/) on Cu(100)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stoehr, J.; Outka, D.A.; Madix, R.J.

    1985-03-25

    Surface extended-x-ray-absorption fine-structure measurements reveal that formate (HCO/sub 2/) groups on Cu(100) chemisorb via the two oxygen atoms in adjacent fourfold hollow sites with an average O-Cu nearest-neighbor bond length of 2.38 +- 0.03 A. This distance is sig- nificantly (approx.0.4 A) longer than typical O-Cu bonds in bulk compounds and all known surface complexes. The unusually large O-Cu distance is attributed to a steric effect involving the C atom in HCO/sub 2/ and the nearest-neighbor Cu surface atoms.

  5. Digital live-tracking 3-dimensional minisensors for recording head orientation during image acquisition.

    PubMed

    de Paula, Leonardo Koerich; Ackerman, James L; Carvalho, Felipe de Assis Ribeiro; Eidson, Lindsey; Cevidanes, Lucia Helena Soares

    2012-01-01

    Our objective was to test the value of minisensors for recording unrestrained head position with 6 degrees of freedom during 3-dimensional stereophotogrammetry. Four 3-dimensional pictures (3dMD, Atlanta, Ga) were taken of 20 volunteers as follows: (1) in unrestrained head position, (2) a repeat of picture 1, (3) in unrestrained head position wearing a headset with 3-dimensional live tracking sensors (3-D Guidance trackSTAR; Ascension Technology, Burlington, Vt), and (4) a repeat of picture 3. The sensors were used to track the x, y, and z coordinates (pitch, roll, and yaw) of the head in space. The patients were seated in front of a mirror and asked to stand and take a walk between each acquisition. Eight landmarks were identified in each 3-dimensional picture (nasion, tip of nose, subnasale, right and left lip commissures, midpoints of upper and lower lip vermilions, soft-tissue B-point). The distances between correspondent landmarks were measured between pictures 1 and 2 and 3 and 4 with software. The Student t test was used to test differences between unrestrained head position with and without sensors. Interlandmark distances for pictures 1 and 2 (head position without the sensors) and pictures 3 and 4 (head position with sensors) were consistent for all landmarks, indicating that roll, pitch, and yaw of the head are controlled independently of the sensors. However, interlandmark distances were on average 17.34 ± 0.32 mm between pictures 1 and 2. Between pictures 3 and 4, the distances averaged 6.17 ± 0.15 mm. All interlandmark distances were significantly different between the 2 methods (P <0.001). The use of 3-dimensional live-tracking sensors aids the reproducibility of patient head positioning during repeated or follow-up acquisitions of 3-dimensional stereophotogrammetry. Even with sensors, differences in spatial head position between acquisitions still require additional registration procedures. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  6. Movements of wolves at the northern extreme of the species' range, including during four months of darkness

    USGS Publications Warehouse

    Mech, L.D.; Cluff, H.D.

    2011-01-01

    Information about wolf (Canis lupus) movements anywhere near the northern extreme of the species' range in the High Arctic (<75??N latitude) are lacking. There, wolves prey primarily on muskoxen (Ovibos moschatus) and must survive 4 months of 24 hr/day winter darkness and temperatures reaching -53 C. The extent to which wolves remain active and prey on muskoxen during the dark period are unknown, for the closest area where information is available about winter wolf movements is >2,250 km south. We studied a pack of ???20 wolves on Ellesmere Island, Nunavut, Canada (80??N latitude) from July 2009 through mid-April 2010 by collaring a lead wolf with a Global Positioning System (GPS)/Argos radio collar. The collar recorded the wolf's precise locations at 6:00 a.m. and 6:00 p.m. daily and transmitted the locations by satellite to our email. Straight-line distances between consecutive 12-hr locations varied between 0 and 76 km. Mean (SE) linear distance between consecutive locations (n = 554) was 11 (0.5) km. Total minimum distance traveled was 5,979 km, and total area covered was 6,640 km2, the largest wolf range reported. The wolf and presumably his pack once made a 263-km (straight-line distance) foray to the southeast during 19-28 January 2010, returning 29 January to 1 February at an average of 41 km/day straight-line distances between 12-hr locations. This study produced the first detailed movement information about any large mammal in the High Arctic, and the average movements during the dark period did not differ from those afterwards. Wolf movements during the dark period in the highest latitudes match those of the other seasons and generally those of wolves in lower latitudes, and, at least with the gross movements measurable by our methods, the 4-month period without direct sunlight produced little change in movements. ?? 2011 Mech, Cluff.

  7. Movements of wolves at the northern extreme of the species' range, including during four months of darkness

    USGS Publications Warehouse

    Mech, L. David; Cluff, H. Dean

    2011-01-01

    Information about wolf (Canis lupus) movements anywhere near the northern extreme of the species' range in the High Arctic (>75°N latitude) are lacking. There, wolves prey primarily on muskoxen (Ovibos moschatus) and must survive 4 months of 24 hr/day winter darkness and temperatures reaching -53 C. The extent to which wolves remain active and prey on muskoxen during the dark period are unknown, for the closest area where information is available about winter wolf movements is >2,250 km south. We studied a pack of ≥20 wolves on Ellesmere Island, Nunavut, Canada (80°N latitude) from July 2009 through mid-April 2010 by collaring a lead wolf with a Global Positioning System (GPS)/Argos radio collar. The collar recorded the wolf's precise locations at 6:00 a.m. and 6:00 p.m. daily and transmitted the locations by satellite to our email. Straight-line distances between consecutive 12-hr locations varied between 0 and 76 km. Mean (SE) linear distance between consecutive locations (n = 554) was 11 (0.5) km. Total minimum distance traveled was 5,979 km, and total area covered was 6,640 km2, the largest wolf range reported. The wolf and presumably his pack once made a 263-km (straight-line distance) foray to the southeast during 19–28 January 2010, returning 29 January to 1 February at an average of 41 km/day straight-line distances between 12-hr locations. This study produced the first detailed movement information about any large mammal in the High Arctic, and the average movements during the dark period did not differ from those afterwards. Wolf movements during the dark period in the highest latitudes match those of the other seasons and generally those of wolves in lower latitudes, and, at least with the gross movements measurable by our methods, the 4-month period without direct sunlight produced little change in movements.

  8. Extended depth of focus contact lenses vs. two commercial multifocals: Part 2. Visual performance after 1 week of lens wear.

    PubMed

    Bakaraju, Ravi C; Tilia, Daniel; Sha, Jennifer; Diec, Jennie; Chung, Jiyoon; Kho, Danny; Delaney, Shona; Munro, Anna; Thomas, Varghese

    To compare the visual performance of prototype contact lenses designed via deliberate manipulation of higher-order spherical aberrations to extend-depth-of-focus with two commercial multifocals, after 1 week of lens wear. In a prospective, participant-masked, cross-over, randomized, 1-week dispensing clinical-trial, 43 presbyopes [age: 42-63 years] each wore AIROPTIX Aqua multifocal (AOMF), ACUVUE OASYS for presbyopia (AOP) and extended-depth-of-focus prototypes (EDOF) appropriate to their add requirements. Measurements comprised high-contrast-visual-acuity (HCVA) at 6m, 70cm, 50cm and 40cm; low-contrast-visual-acuity (LCVA) and contrast-sensitivity (CS) at 6m and stereopsis at 40cm. A self-administered questionnaire on a numeric-rating-scale (1-10) assessed subjective visual performance comprising clarity-of-vision and lack-of-ghosting at various distances during day/night-viewing conditions and overall-vision-satisfaction. EDOF was significantly better than AOMF and AOP for HCVA averaged across distances (p≤0.038); significantly worse than AOMF for LCVA (p=0.021) and significantly worse than AOMF for CS in medium and high add-groups (p=0.006). None of these differences were clinically significant (≤2 letters). EDOF was significantly better than AOMF and AOP for mean stereoacuity (36 and 13 seconds-of-arc, respectively: p≤0.05). For clarity-of-vision, EDOF was significantly better than AOP at all distances and AOMF at intermediate and near (p≤0.028). For lack-of-ghosting averaged across distances, EDOF was significantly better than AOP (p<0.001) but not AOMF (p=0.186). EDOF was significantly better than AOMF and AOP for overall-vision-satisfaction (p≤0.024). EDOF provides better intermediate and near vision performance than either AOMF or AOP with no difference for distance vision after 1 week of lens wear. Copyright © 2017 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.

  9. Comparison of surface characteristics of retrieved cobalt-chromium femoral heads with and without ion implantation.

    PubMed

    McGrory, Brian J; Ruterbories, James M; Pawar, Vivek D; Thomas, Reginald K; Salehi, Abraham B

    2012-01-01

    Nitrogen ion implantation of CoCr is reported to produce increased surface hardness and a lower friction surface. Femoral heads with and without ion implantation retrieved from 1997 to 2003 were evaluated for surface roughness (average surface roughness [Ra], mean peak height [Rpm], and maximum distance from peak to valley [Rmax]), nanohardness, and the ion-treated layer thickness. The difference in average Rmax (P = .033) and average Rpm (P = .008) was statistically significant, but there was no correlation between the average or maximum roughness parameters (average surface roughness, Rmax, and Rpm) and time in vivo (P > .05). Overall, nanohardness was greater for the low-friction ion-treated heads (P < .001); and it decreased with increasing time in vivo (P = .01). Ion treatment produces an increased surface hardness, but the advantage of this increased hardness appears to dissipate over time in vivo. Copyright © 2012 Elsevier Inc. All rights reserved.

  10. The origin of consistent protein structure refinement from structural averaging.

    PubMed

    Park, Hahnbeom; DiMaio, Frank; Baker, David

    2015-06-02

    Recent studies have shown that explicit solvent molecular dynamics (MD) simulation followed by structural averaging can consistently improve protein structure models. We find that improvement upon averaging is not limited to explicit water MD simulation, as consistent improvements are also observed for more efficient implicit solvent MD or Monte Carlo minimization simulations. To determine the origin of these improvements, we examine the changes in model accuracy brought about by averaging at the individual residue level. We find that the improvement in model quality from averaging results from the superposition of two effects: a dampening of deviations from the correct structure in the least well modeled regions, and a reinforcement of consistent movements towards the correct structure in better modeled regions. These observations are consistent with an energy landscape model in which the magnitude of the energy gradient toward the native structure decreases with increasing distance from the native state. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. [Significance of lateral release in the therapy of patellar chondromalacia].

    PubMed

    Krüger, T; Göbel, F; Huschenbett, A; Hein, W

    2002-10-01

    A retrospective study was performed in 26 patients who underwent an operation for femoro-patellar pain due to a patellar chondromalacia with or without minor patellar dislocation/lateral pressure syndrome. The average age of the patients was 28.5 (15-39) years. 22 of the 26 patients revealed minor chondral damages of the stages 1 and 2 according to Outerbridge. In 12 patients ("lavage" group), an arthroscopic joint debridement only was carried out, while an additional open, lateral retinaculum release was made in 14 patients ("lateral release" group). The patella's distance of dislocation according to Hepp was reduced on an average of 3.0 (0-7) mm (p = 0.0019). The results of Bentley's score obtained during the follow-up interval on an average of 30.1 (9 to 60) months were almost identical for both groups. "Good" and "very good" results were achieved in the "lavage" group (83.3 %) and "lateral release" group (78.6 % of the patients). Lateral release should be used in cases of patellar decentration between 5 and 10 mm and adequate pain symptoms. The post-operative distance of dislocation should be less than 5 mm. Under such conditions and with minor chondral damage, a combined approach by using an arthroscopic joint debridement and open lateral release is promising to treat a patellar dislocation/lateral pressure syndrome.

  12. [Comparative analysis on the complete genome sequence of mumps epidemic strain and mumps vaccine strain S79 isolated in Zhejiang province, China between year 2005 and 2010].

    PubMed

    Zhang, Dong-Yan; Feng, Yan; Zhong, Shu-Ling; Lu, Yi-Yu; Zhuang, Fang-Cheng; Xu, Chang-Ping

    2012-03-01

    To compare the differences in the complete genome sequence between mumps epidemic strain and mumps vaccine strain S79 isolated in Zhejiang province. A total of 4 mumps epidemic strains, which were separated from Zhejiang province during 2005 to 2010, named as ZJ05-1, ZJ06-3, ZJ08-1 and ZJ10-1 were selected in the study. The complete genome sequences were amplified using RT-PCR. The genetic differences between vaccine strain S79 and other genotype strains were compared; while the genetic-distance was calculated and the evolution was analyzed. The biggest difference between the 4 epidemic strains and the vaccine strain S79 was found on the membrane associated protein gene; whose average nucleotide differential number was 42.5 +/- 3.0 and the average variant ratio was 13.6%; while the mean amino acid differential number was 12.8 +/- 1.5 and the average variant ratio was 22.4%. The smallest difference among the 4 epidemic strains and the vaccine strain was found in stromatin genes, whose average nucleotide differential number was 73.8 +/- 2.5 and the average variant ratio was 5.9%; while the mean amino acid differential number was 3.0 +/- 0.8 and the average variant ratio was 0.8%. The dn/ds value of the stromatin genes of the 4 epidemic strains reached the highest, as 0.6526; but without any positive pressure (dn/ds < 1, chi2 = 0.87, P > 0.05). There were mutations happened on the known antigen epitope, as 8th amino acid of membrane associated protein genes and on the 336th and 356th amino acid of hemagglutinin/neuraminidase proteins. Compared with the vaccine strain, the glycosylation sites of ZJ05-1, ZJ06-3, ZJ08-1 and ZJ10-1 increased 1, 1, 2 and 2 respectively. The complete amino acid sequence of all strains showed that there were 17 characteristic sites found on the genotype-F mumps strain. Within the complete genome, the genetic-distance between epidemic strains and vaccine strains in Zhejiang province (0.071) was significantly larger than the genetic-distance between strains in Yunnan province (0.013); the difference showing statistical significance (t = 4.14, P < 0.05). Except nucleocapsid protein genes, all the genes shared similar evolution tree. There were significant differences found in the genes between mumps epidemic strain and mumps vaccine in Zhejiang province.

  13. Simulated changes in water levels caused bypotential changes in pumping from shallow aquifersof Virginia Beach, Virginia

    USGS Publications Warehouse

    Smith, Barry S.

    2005-01-01

    A steady-state ground-water flow model of the southern watersheds of Virginia Beach, Virginia, was refined and used to simulate changes in aquifer water levels caused by potential changes in pumping in the Transition Area of Virginia Beach, Va., a 20-square mile planning zone that runs through the middle of the city. Cessation of dewatering at borrow pits, pumping to irrigate a golf course, pumping to irrigate lawns of a hypothetical neighborhood, and pumping to irrigate both the golf course and lawns of the hypothetical neighborhood were simulated. Simulated recoveries from cessation of dewatering of borrow pits were generally restricted to the immediate area of the pits. The simulated recoveries averaged about 20 feet (ft) near the center of the cells representing the active areas of the pits and 2 ft at the cells representing the extent of the pits. At a golf course, 4 hypothetical wells pumping 300,000 gallons per day (gal/d) from the Yorktown sand aquifer resulted in drawdowns averaging 10 ft in the pumping cells and 1 ft at a distance of 1.2 miles (mi) from the center of the pumping cells. The extent of the 1-ft drawdown was virtually the same as that simulated previously and reported in a permit application for the golf course. Simulated pumping of 150,000 gal/d from 4 cells in the confined sand aquifer representing a 40-acre neighborhood resulted in drawdowns averaging 7 ft in the pumping cells and 1 ft at a distance of 0.8 mi from the center of the cells. Simulated pumping of 300,000 gal/d from the same 4 cells resulted in drawdowns averaging 15 ft in the pumping cells and 1 ft at a distance of 1.4 mi from the center of the cells. Simulated pumping of 150,000 gal/d at the golf course and another 150,000 gal/d in the hypothetical neighborhood resulted in drawdowns that averaged 5 ft around the cells representing the golf course wells spaced 1,300 ft apart and 7 ft around the contiguous cells representing the 40-acre neighborhood. A drawdown of 1 ft encompassed most of the eastern half of the Transition Area.

  14. Progression of ash canopy thinning and dieback outward from the initial infestation of emerald ash borer (Coleoptera: Buprestidae) in southeastern Michigan.

    PubMed

    Smitley, David; Davis, Terrance; Rebek, Eric

    2008-10-01

    Our objective was to characterize the rate at which ash (Fraxinus spp.) trees decline in areas adjacent to the leading edge of visible ash canopy thinning due to emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae). Trees in southeastern Michigan were surveyed from 2003 to 2006 for canopy thinning and dieback by comparing survey trees with a set of 11 standard photographs. Freeways stemming from Detroit in all directions were used as survey transects. Between 750 and 1,100 trees were surveyed each year. A rapid method of sampling populations of emerald ash borer was developed by counting emerald ash borer emergence holes with binoculars and then felling trees to validate binocular counts. Approximately 25% of the trees surveyed for canopy thinning in 2005 and 2006 also were sampled for emerald ash borer emergence holes using binoculars. Regression analysis indicates that 41-53% of the variation in ash canopy thinning can be explained by the number of emerald ash borer emergence holes per tree. Emerald ash borer emergence holes were found at every site where ash canopy thinning averaged > 40%. In 2003, ash canopy thinning averaged 40% at a distance of 19.3 km from the epicenter of the emerald ash borer infestation in Canton. By 2006, the point at which ash trees averaged 40% canopy thinning had increased to a distance of 51.2 km away from Canton. Therefore, the point at which ash trees averaged 40% canopy thinning, a state of decline clearly visible to the average person, moved outward at a rate of 10.6 km/yr during this period.

  15. On estimating attenuation from the amplitude of the spectrally whitened ambient seismic field

    NASA Astrophysics Data System (ADS)

    Weemstra, Cornelis; Westra, Willem; Snieder, Roel; Boschi, Lapo

    2014-06-01

    Measuring attenuation on the basis of interferometric, receiver-receiver surface waves is a non-trivial task: the amplitude, more than the phase, of ensemble-averaged cross-correlations is strongly affected by non-uniformities in the ambient wavefield. In addition, ambient noise data are typically pre-processed in ways that affect the amplitude itself. Some authors have recently attempted to measure attenuation in receiver-receiver cross-correlations obtained after the usual pre-processing of seismic ambient-noise records, including, most notably, spectral whitening. Spectral whitening replaces the cross-spectrum with a unit amplitude spectrum. It is generally assumed that cross-terms have cancelled each other prior to spectral whitening. Cross-terms are peaks in the cross-correlation due to simultaneously acting noise sources, that is, spurious traveltime delays due to constructive interference of signal coming from different sources. Cancellation of these cross-terms is a requirement for the successful retrieval of interferometric receiver-receiver signal and results from ensemble averaging. In practice, ensemble averaging is replaced by integrating over sufficiently long time or averaging over several cross-correlation windows. Contrary to the general assumption, we show in this study that cross-terms are not required to cancel each other prior to spectral whitening, but may also cancel each other after the whitening procedure. Specifically, we derive an analytic approximation for the amplitude difference associated with the reversed order of cancellation and normalization. Our approximation shows that an amplitude decrease results from the reversed order. This decrease is predominantly non-linear at small receiver-receiver distances: at distances smaller than approximately two wavelengths, whitening prior to ensemble averaging causes a significantly stronger decay of the cross-spectrum.

  16. Transposition of branches of radial nerve innervating supinator to posterior interosseous nerve for functional reconstruction of finger and thumb extension in 4 patients with middle and lower trunk root avulsion injuries of brachial plexus.

    PubMed

    Wu, Xia; Cong, Xiao-Bing; Huang, Qi-Shun; Ai, Fang-Xin; Liu, Yu-Tian; Lu, Xiao-Cheng; Li, Jin; Weng, Yu-Xiong; Chen, Zhen-Bing

    2017-12-01

    This study aimed to investigate the reconstruction of the thumb and finger extension function in patients with middle and lower trunk root avulsion injuries of the brachial plexus. From April 2010 to January 2015, we enrolled in this study 4 patients diagnosed with middle and lower trunk root avulsion injuries of the brachial plexus via imaging tests, electrophysiological examinations, and clinical confirmation. Muscular branches of the radial nerve, which innervate the supinator in the forearm, were transposed to the posterior interosseous nerve to reconstruct the thumb and finger extension function. Electrophysiological findings and muscle strength of the extensor pollicis longus and extensor digitorum communis, as well as the distance between the thumb tip and index finger tip, were monitored. All patients were followed up for 24 to 30 months, with an average of 27.5 months. Motor unit potentials (MUP) of the extensor digitorum communis appeared at an average of 3.8 months, while MUP of the extensor pollicis longus appeared at an average of 7 months. Compound muscle action potential (CMAP) appeared at an average of 9 months in the extensor digitorum communis, and 12 months in the extensor pollicis longus. Furthermore, the muscle strength of the extensor pollicis longus and extensor digitorum communis both reached grade III at 21 months. Lastly, the average distance between the thumb tip and index finger tip was 8.8 cm at 21 months. In conclusion, for patients with middle and lower trunk injuries of the brachial plexus, transposition of the muscular branches of the radial nerve innervating the supinator to the posterior interosseous nerve for the reconstruction of thumb and finger extension function is practicable and feasible.

  17. Do stochastic inhomogeneities affect dark-energy precision measurements?

    PubMed

    Ben-Dayan, I; Gasperini, M; Marozzi, G; Nugier, F; Veneziano, G

    2013-01-11

    The effect of a stochastic background of cosmological perturbations on the luminosity-redshift relation is computed to second order through a recently proposed covariant and gauge-invariant light-cone averaging procedure. The resulting expressions are free from both ultraviolet and infrared divergences, implying that such perturbations cannot mimic a sizable fraction of dark energy. Different averages are estimated and depend on the particular function of the luminosity distance being averaged. The energy flux being minimally affected by perturbations at large z is proposed as the best choice for precision estimates of dark-energy parameters. Nonetheless, its irreducible (stochastic) variance induces statistical errors on Ω(Λ)(z) typically lying in the few-percent range.

  18. Increased Vertebral Bone Mineral in Response to Reduced Exercise in Amenorrheic Runners

    PubMed Central

    Lindberg, Jill S.; Hunt, Marjorie M.; Wade, Charles E.; Powell, Malcolm R.; Ducey, Diane E.

    1987-01-01

    Seven female runners found to have exercise-induced amenorrhea and decreased bone mineral were reevaluated after 15 months. During the 15-month period, four runners took supplemental calcium and reduced their weekly running distance by 43%, resulting in an average 5% increase in body weight, increased estradiol levels and eumenorrhea. Bone mineral content increased from 1.003±0.097 to 1.070±0.089 grams per cm.2 Three runners continued to have amenorrhea, with no change in running distance or body weight. Estradiol levels remained abnormally low and there was no significant change in the bone mineral content, although all three took supplemental calcium. We found that early osteopenia associated with exercise-induced menstrual dysfunction improved when runners reduced their running distance, gained weight and became eumenorrheic. ImagesFigure 1. PMID:3825107

  19. Bifocal Stereo for Multipath Person Re-Identification

    NASA Astrophysics Data System (ADS)

    Blott, G.; Heipke, C.

    2017-11-01

    This work presents an approach for the task of person re-identification by exploiting bifocal stereo cameras. Present monocular person re-identification approaches show a decreasing working distance, when increasing the image resolution to obtain a higher reidentification performance. We propose a novel 3D multipath bifocal approach, containing a rectilinear lens with larger focal length for long range distances and a fish eye lens of a smaller focal length for the near range. The person re-identification performance is at least on par with 2D re-identification approaches but the working distance of the approach is increased and on average 10% more re-identification performance can be achieved in the overlapping field of view compared to a single camera. In addition, the 3D information is exploited from the overlapping field of view to solve potential 2D ambiguities.

  20. Oxygen production rates for P/Halley over much of the 1985-1986 apparition

    NASA Technical Reports Server (NTRS)

    Spinrad, Hyron; Mccarthy, Patrick J.; Strauss, Michael A.

    1986-01-01

    Long slit CCD spectrophotometry of comet P/Halley in the visible region was used to measure the production rate of atomic oxygen during the 1985/86 apparition. The observations cover a large range of heliocentric distances, since the technique is applicable to apparently bright and faint comets. The cometary gas production rate for P/Halley increases rapidly with decreasing heliocentric distance toward perihelion and is systematicaly larger at a given heliocentric distance for the postperihelion observations. The average production rate for O1D on the day of the Giotto flyby is 4 times 10 to the 28th power atoms/sec giving an extrapolated total water production rate of 6 times 10 to the 29th power mols/sec. A method for comparing the absolute cometary gas production rates for different comets is discussed.

  1. Ab initio Potential Energy Surface for H-H2

    NASA Technical Reports Server (NTRS)

    Partridge, Harry; Bauschlicher, Charles W., Jr.; Stallcop, James R.; Levin, Eugene

    1993-01-01

    Ab initio calculations employing large basis sets are performed to determine an accurate potential energy surface for H-H2 interactions for a broad range of separation distances. At large distances, the spherically averaged potential determined from the calculated energies agrees well with the corresponding results determined from dispersion coefficients; the van der Waals well depth is predicted to be 75 +/- (mu)E(sub h). Large basis sets have also been applied to reexamine the accuracy of theoretical repulsive potential energy surfaces. Multipolar expansions of the computed H-H2 potential energy surface are reported for four internuclear separation distances (1.2, 1.401, 1.449, and 1.7a(sub 0) of the hydrogen molecule. The differential elastic scattering cross section calculated from the present results is compared with the measurements from a crossed beam experiment.

  2. Tin Valence and Local Environments in Silicate Glasses as Determined From X-ray Absorption Spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McKeown,D.; Buechele, A.; Gan, H.

    2008-01-01

    X-ray absorption spectroscopy (XAS) was used to characterize the tin (Sn) environments in four borosilicate glass nuclear waste formulations, two silicate float glasses, and three potassium aluminosilicate glasses. Sn K-edge XAS data of most glasses investigated indicate Sn4+O6 units with average Sn-O distances near 2.03 Angstroms. XAS data for a float glass fabricated under reducing conditions show a mixture of Sn4+O6 and Sn2+O4 sites. XAS data for three glasses indicate Sn-Sn distances ranging from 3.43 to 3.53 Angstroms, that suggest Sn4+O6 units linking with each other, while the 4.96 Angstroms Sn-Sn distance for one waste glass suggests clustering of unlinkedmore » Sn4+O6 units.« less

  3. Splash-cup plants accelerate raindrops to disperse seeds.

    PubMed

    Amador, Guillermo J; Yamada, Yasukuni; McCurley, Matthew; Hu, David L

    2013-02-01

    The conical flowers of splash-cup plants Chrysosplenium and Mazus catch raindrops opportunistically, exploiting the subsequent splash to disperse their seeds. In this combined experimental and theoretical study, we elucidate their mechanism for maximizing dispersal distance. We fabricate conical plant mimics using three-dimensional printing, and use high-speed video to visualize splash profiles and seed travel distance. Drop impacts that strike the cup off-centre achieve the largest dispersal distances of up to 1 m. Such distances are achieved because splash speeds are three to five times faster than incoming drop speeds, and so faster than the traditionally studied splashes occurring upon horizontal surfaces. This anomalous splash speed is because of the superposition of two components of momentum, one associated with a component of the drop's motion parallel to the splash-cup surface, and the other associated with film spreading induced by impact with the splash-cup. Our model incorporating these effects predicts the observed dispersal distance within 6-18% error. According to our experiments, the optimal cone angle for the splash-cup is 40°, a value consistent with the average of five species of splash-cup plants. This optimal angle arises from the competing effects of velocity amplification and projectile launching angle.

  4. Laser rangefinders for autonomous intelligent cruise control systems

    NASA Astrophysics Data System (ADS)

    Journet, Bernard A.; Bazin, Gaelle

    1998-01-01

    THe purpose of this paper is to show to what kind of application laser range-finders can be used inside Autonomous Intelligent Cruise Control systems. Even if laser systems present good performances the safety and technical considerations are very restrictive. As the system is used in the outside, the emitted average output power must respect the rather low level of 1A class. Obstacle detection or collision avoidance require a 200 meters range. Moreover bad weather conditions, like rain or fog, ar disastrous. We have conducted measurements on laser rangefinder using different targets and at different distances. We can infer that except for cooperative targets low power laser rangefinder are not powerful enough for long distance measurement. Radars, like 77 GHz systems, are better adapted to such cases. But in case of short distances measurement, range around 10 meters, with a minimum distance around twenty centimeters, laser rangefinders are really useful with good resolution and rather low cost. Applications can have the following of white lines on the road, the target being easily cooperative, detection of vehicles in the vicinity, that means car convoy traffic control or parking assistance, the target surface being indifferent at short distances.

  5. The association between commuter cycling and sickness absence.

    PubMed

    Hendriksen, Ingrid J M; Simons, Monique; Garre, Francisca Galindo; Hildebrandt, Vincent H

    2010-08-01

    To study the association between commuter cycling and all-cause sickness absence, and the possible dose-response relationship between absenteeism and the distance, frequency and speed of commuter cycling. Cross-sectional data about cycling in 1236 Dutch employees were collected using a self-report questionnaire. Company absenteeism records were checked over a one-year period (May 2007-April 2008). Propensity scores were used to make groups comparable and to adjust for confounders. Zero-inflated Poisson models were used to assess differences in absenteeism between cyclists and non-cyclists. The mean total duration of absenteeism over the study year was more than 1 day shorter in cyclists than in non-cyclists. This can be explained by the higher proportion of people with no absenteeism in the cycling group. A dose-response relationship was observed between the speed and distance of cycling and absenteeism. Compared to people who cycle a short distance (

  6. Advanced two-layer level set with a soft distance constraint for dual surfaces segmentation in medical images

    NASA Astrophysics Data System (ADS)

    Ji, Yuanbo; van der Geest, Rob J.; Nazarian, Saman; Lelieveldt, Boudewijn P. F.; Tao, Qian

    2018-03-01

    Anatomical objects in medical images very often have dual contours or surfaces that are highly correlated. Manually segmenting both of them by following local image details is tedious and subjective. In this study, we proposed a two-layer region-based level set method with a soft distance constraint, which not only regularizes the level set evolution at two levels, but also imposes prior information on wall thickness in an effective manner. By updating the level set function and distance constraint functions alternatingly, the method simultaneously optimizes both contours while regularizing their distance. The method was applied to segment the inner and outer wall of both left atrium (LA) and left ventricle (LV) from MR images, using a rough initialization from inside the blood pool. Compared to manual annotation from experience observers, the proposed method achieved an average perpendicular distance (APD) of less than 1mm for the LA segmentation, and less than 1.5mm for the LV segmentation, at both inner and outer contours. The method can be used as a practical tool for fast and accurate dual wall annotations given proper initialization.

  7. The relationship between traffic noise and insomnia among adult Japanese women

    NASA Astrophysics Data System (ADS)

    Sasazawa, Y.; Kawada, T.; Kiryu, Y.; Suzuki, S.

    2004-10-01

    To clarify the relationship between traffic noise and insomnia, the authors conducted a survey and measured the actual sound level of noise in an urban area. Questionnaires were distributed to adult women who lived within 150 m from two major roads and were completed by 648 of the 1286 subjects (50.4%). The area was divided into three zones according to distance from the road (more than 50, 20-50 and 0-19.9 m). Fifty-seven subjects (8.8%) were classified as having insomnia. Average values of sound level at distances of 20, 50, and 100 m from the major road were Leq 64.7, 57.1, and 51.8 dBA, respectively. Overall, there were no significant differences among the three zones in the prevalence of insomnia and no association between distance from the road and insomnia. However, the result from a sub-data set of the subjects who lived in the areas that showed decreasing noise level as the distance from the main road increased showed that distance from the road was associated with insomnia. This study suggests that researchers should consider the actual traffic situation and its sound level in epidemiological studies about the effects of traffic noise on insomnia.

  8. Effects of joint position on the distraction distance during grade III glenohumeral joint distraction in healthy individuals

    PubMed Central

    Park, Sam-Sik; Kim, Bo-Kyung; Moon, Ok-Kon; Choi, Wan-Suk

    2015-01-01

    [Purpose] The study investigated the effects of joint position on the distraction distance during Grade III glenohumeral joint distraction in healthy individuals. [Subjects and Methods] Twenty adults in their forties without shoulder disease were randomly divided into neutral position group (NPG; n = 7), resting position group (RPG; n = 7), and end range position group (ERPG; n = 6). After Kaltenborn Grade III distraction for 40s, the distance between glenoid fossa and humeral head was measured by ultrasound. [Results] The average distances between the humeral head and glenoid fossa before distraction were 2.86 ± 0.81, 3.21 ± 0.47, and 3.55 ± 0.59 mm for the NP, RP, and ERP groups. The distances after applying distraction were 3.12 ± 0.51, 3.86 ± 0.55, and 4.35 ± 0.32 mm. Between-group comparison after applying distraction revealed no significant differences between the NP and RP groups, while there was a statistically significant difference between the NP and RP groups, as well as between the NP and ERP groups. [Conclusion] Joint space was largest in ERP individuals when performing manual distraction. PMID:26644692

  9. Human-tracking strategies for a six-legged rescue robot based on distance and view

    NASA Astrophysics Data System (ADS)

    Pan, Yang; Gao, Feng; Qi, Chenkun; Chai, Xun

    2016-03-01

    Human tracking is an important issue for intelligent robotic control and can be used in many scenarios, such as robotic services and human-robot cooperation. Most of current human-tracking methods are targeted for mobile/tracked robots, but few of them can be used for legged robots. Two novel human-tracking strategies, view priority strategy and distance priority strategy, are proposed specially for legged robots, which enable them to track humans in various complex terrains. View priority strategy focuses on keeping humans in its view angle arrange with priority, while its counterpart, distance priority strategy, focuses on keeping human at a reasonable distance with priority. To evaluate these strategies, two indexes(average and minimum tracking capability) are defined. With the help of these indexes, the view priority strategy shows advantages compared with distance priority strategy. The optimization is done in terms of these indexes, which let the robot has maximum tracking capability. The simulation results show that the robot can track humans with different curves like square, circular, sine and screw paths. Two novel control strategies are proposed which specially concerning legged robot characteristics to solve human tracking problems more efficiently in rescue circumstances.

  10. X-ray investigation of molten crystal hydrates H2SO4(nH2O) and HNO3(nH2O)

    NASA Technical Reports Server (NTRS)

    Romanova, A. V.; Skryshevskiy, A. F.

    1979-01-01

    Integral analysis of the intensity of the electron density distribution curve in molten crystal hydrates provided by X-ray analysis, permits the following conclusions on the structure of the complex SO and NO ions, and the short-range order in the structure of the solution. The SO4 ion in the solution has a tetrahedral structure with an S to O distance equal to 1.5 A. For the NO3 in the solution, a planar triangular shape is probable, with an N to O distance equal to 1.2 A. Preferential distances between each of the oxygens of the SO ion and the nearest molecules of water proved near to the corresponding distances in solid crystal hydrates. For an (H2SO4)(H2O) solution, the average number of water molecules surrounding each oxygen atom of the SO4 (--) ion was on the order of 1.3 molecules. Hence the preferential distances between the water molecules and the oxygen atoms of the SO ion, and the preference of their mutual position, correspond to the fixed position of these same elements of the structure in the solid crystal hydrate.

  11. Genetic diversity assessment of anoxygenic photosynthetic bacteria by distance-based grouping analysis of pufM sequences.

    PubMed

    Zeng, Y H; Chen, X H; Jiao, N Z

    2007-12-01

    To assess how completely the diversity of anoxygenic phototrophic bacteria (APB) was sampled in natural environments. All nucleotide sequences of the APB marker gene pufM from cultures and environmental clones were retrieved from the GenBank database. A set of cutoff values (sequence distances 0.06, 0.15 and 0.48 for species, genus, and (sub)phylum levels, respectively) was established using a distance-based grouping program. Analysis of the environmental clones revealed that current efforts on APB isolation and sampling in natural environments are largely inadequate. Analysis of the average distance between each identified genus and an uncultured environmental pufM sequence indicated that the majority of cultured APB genera lack environmental representatives. The distance-based grouping method is fast and efficient for bulk functional gene sequences analysis. The results clearly show that we are at a relatively early stage in sampling the global richness of APB species. Periodical assessment will undoubtedly facilitate in-depth analysis of potential biogeographical distribution pattern of APB. This is the first attempt to assess the present understanding of APB diversity in natural environments. The method used is also useful for assessing the diversity of other functional genes.

  12. Evaluation of rockfish conservation area networks in the United States and Canada relative to the dispersal distance for black rockfish (Sebastes melanops)

    PubMed Central

    Lotterhos, Katie E; Dick, Stefan J; Haggarty, Dana R

    2014-01-01

    Marine reserves networks are implemented as a way to mitigate the impact of fishing on marine ecosystems. Theory suggests that a reserve network will function synergistically when connected by dispersal, but the scale of dispersal is often unknown. On the Pacific coast of the United States and Canada, both countries have recently implemented a number of rockfish conservation areas (RCAs) to protect exploited rockfish species, but no study has evaluated the connectivity within networks in each country or between the two countries. We used isolation-by-distance theory to estimate the scale of dispersal from microsatellite data in the black rockfish, Sebastes melanops, and compared this estimate with the distance between RCAs that would protect this species. Within each country, we found that the distance between RCAs was generally within the confidence intervals of mean dispersal per generation. The distance between these two RCA networks, however, was greater than the average dispersal per generation. The data were also consistent with a genetic break between southern Oregon and central Oregon. We discuss whether additional nearshore RCAs in southern Oregon and Washington would help promote connectivity between RCA's for shallow-water rockfishes. PMID:24567745

  13. A Formula for Planning and Predicting Postoperative Mammoplasty Results.

    PubMed

    Smithson, Mary G; Collawn, Sherry S; Mousa, Mina S; Bramel, Carly M

    2017-06-01

    For women with macromastia, reduction mammoplasty is a safe and effective solution to increasing quality of life through alleviating pain and improving aesthetics. This study developed a way to combine a surgeon's view of breast measurement (volume) with a patient's view of breast measurement (distance between nipple and notch, inframammary fold, or midline) to provide patients with a better understanding of expected surgical outcomes after breast reduction with a medial superior pedicle. An institutional review board approved retrospective chart review was performed on all medial superior pedicle reduction mammoplasties performed by a single surgeon at a university medical center from 2008 to 2016, and a total of 133 patients were identified. Measurements of interest for this study were nipple to sternal notch (N-S), nipple to inframammary fold (N-I), nipple to midline (N-M), and breast diameter (BD). The average bilateral change per measurement was calculated for each patient in centimeters. Change was averaged for left and right breasts for N-S, N-I, N-M, and BD per patient. Grams removed for left and right breasts were also averaged. Each measurement of average change was divided by the gram average and multiplied by 100 to obtain centimeter change per 100 grams. Individual patient measurements per type of measurement were averaged to achieve a final improvement reported in centimeters per 100 g tissue removed per breast. The average change in the N-S distance was calculated to be a decrease of 1.5 ± 0.8 cm/100 g of breast tissue removed. The average change in N-I was calculated to be an overall decrease of 0.7 ± 0.5 cm/100 g. The average change in N-M was calculated to be a decrease of 0.1 ± 0.3 cm/100 g. Finally, the average change in BD was calculated to be 0.0 ± 0.4 cm/100 g. A surgeon's expression of breast measurements in terms of volume can be difficult for a patient to understand and visualize. This study determined the impact volume has on length of typical breast measurements to increase patients' understanding of expected outcomes. In summary, patients can be told to expect to see a nipple elevation of 1.5 cm per 100 grams of breast tissue removed using this medial superior pedicle technique.

  14. A statistical model of false negative and false positive detection of phase singularities.

    PubMed

    Jacquemet, Vincent

    2017-10-01

    The complexity of cardiac fibrillation dynamics can be assessed by analyzing the distribution of phase singularities (PSs) observed using mapping systems. Interelectrode distance, however, limits the accuracy of PS detection. To investigate in a theoretical framework the PS false negative and false positive rates in relation to the characteristics of the mapping system and fibrillation dynamics, we propose a statistical model of phase maps with controllable number and locations of PSs. In this model, phase maps are generated from randomly distributed PSs with physiologically-plausible directions of rotation. Noise and distortion of the phase are added. PSs are detected using topological charge contour integrals on regular grids of varying resolutions. Over 100 × 10 6 realizations of the random field process are used to estimate average false negative and false positive rates using a Monte-Carlo approach. The false detection rates are shown to depend on the average distance between neighboring PSs expressed in units of interelectrode distance, following approximately a power law with exponents in the range of 1.14 to 2 for false negatives and around 2.8 for false positives. In the presence of noise or distortion of phase, false detection rates at high resolution tend to a non-zero noise-dependent lower bound. This model provides an easy-to-implement tool for benchmarking PS detection algorithms over a broad range of configurations with multiple PSs.

  15. An assessment of elephant home ranges and movement patterns during construction of Hulu Terengganu hydroelectric dam, Terengganu using GPS satellite collars

    NASA Astrophysics Data System (ADS)

    Magintan, D.; Shukorb, M. N.; Lihan, Tukimat; Campos, Ahimza-arceiz; Saaban, Salman; Husin, Shahril Mohd; Ahmad, Mohd Noh

    2016-11-01

    Home ranges and movement patterns of elephants during construction of hydroelectric dams were carried out in Hulu Terengganu, Terengganu, Peninsular Malaysia. Two elephants from two herds were captured, collared and released in the catchment area four to five months before inundation started in early October 2014. The two elephants were identified as Puah (female) and Sireh (male). The home range size of each individual during the construction of dams was estimated at 96.53 km2 for Puah and 367.99 km2 for Sireh. The monthly estimates of ranging for Puah was between 5.1 km2 and 38.4 km2 with average monthly ranging of 19.2 ± 4.7, while for Sireh, the monthly ranging estimates were between 20.6 km2 and 184.7 km2 with average monthly ranging at 79.9 ± 34.7. The movement mean rate (based on distance per day) for Puah and Sireh per day were 1.3 ± 0.1 km and 1.9 ± 0.1 km, respectively. Puah movement estimates for the first day after putting the collar was 0.88 km, whereas, the distance movement for Sireh on the first day after the collar was 0.02 km. The total distance travelled for Puah before inundation was 226.18 km, while Sireh covered 267.38 km.

  16. Agreement between methods of measurement of mean aortic wall thickness by MRI.

    PubMed

    Rosero, Eric B; Peshock, Ronald M; Khera, Amit; Clagett, G Patrick; Lo, Hao; Timaran, Carlos

    2009-03-01

    To assess the agreement between three methods of calculation of mean aortic wall thickness (MAWT) using magnetic resonance imaging (MRI). High-resolution MRI of the infrarenal abdominal aorta was performed on 70 subjects with a history of coronary artery disease who were part of a multi-ethnic population-based sample. MAWT was calculated as the mean distance between the adventitial and luminal aortic boundaries using three different methods: average distance at four standard positions (AWT-4P), average distance at 100 automated positions (AWT-100P), and using a mathematical computation derived from the total vessel and luminal areas (AWT-VA). Bland-Altman plots and Passing-Bablok regression analyses were used to assess agreement between methods. Bland-Altman analyses demonstrated a positive bias of 3.02+/-7.31% between the AWT-VA and the AWT-4P methods, and of 1.76+/-6.82% between the AWT-100P and the AWT-4P methods. Passing-Bablok regression analyses demonstrated constant bias between the AWT-4P method and the other two methods. Proportional bias was, however, not evident among the three methods. MRI methods of measurement of MAWT using a limited number of positions of the aortic wall systematically underestimate the MAWT value compared with the method that calculates MAWT from the vessel areas. Copyright (c) 2009 Wiley-Liss, Inc.

  17. Walking, running, and resting under time, distance, and average speed constraints: optimality of walk-run-rest mixtures.

    PubMed

    Long, Leroy L; Srinivasan, Manoj

    2013-04-06

    On a treadmill, humans switch from walking to running beyond a characteristic transition speed. Here, we study human choice between walking and running in a more ecological (non-treadmill) setting. We asked subjects to travel a given distance overground in a given allowed time duration. During this task, the subjects carried, and could look at, a stopwatch that counted down to zero. As expected, if the total time available were large, humans walk the whole distance. If the time available were small, humans mostly run. For an intermediate total time, humans often use a mixture of walking at a slow speed and running at a higher speed. With analytical and computational optimization, we show that using a walk-run mixture at intermediate speeds and a walk-rest mixture at the lowest average speeds is predicted by metabolic energy minimization, even with costs for transients-a consequence of non-convex energy curves. Thus, sometimes, steady locomotion may not be energy optimal, and not preferred, even in the absence of fatigue. Assuming similar non-convex energy curves, we conjecture that similar walk-run mixtures may be energetically beneficial to children following a parent and animals on long leashes. Humans and other animals might also benefit energetically from alternating between moving forward and standing still on a slow and sufficiently long treadmill.

  18. Walking, running, and resting under time, distance, and average speed constraints: optimality of walk–run–rest mixtures

    PubMed Central

    Long, Leroy L.; Srinivasan, Manoj

    2013-01-01

    On a treadmill, humans switch from walking to running beyond a characteristic transition speed. Here, we study human choice between walking and running in a more ecological (non-treadmill) setting. We asked subjects to travel a given distance overground in a given allowed time duration. During this task, the subjects carried, and could look at, a stopwatch that counted down to zero. As expected, if the total time available were large, humans walk the whole distance. If the time available were small, humans mostly run. For an intermediate total time, humans often use a mixture of walking at a slow speed and running at a higher speed. With analytical and computational optimization, we show that using a walk–run mixture at intermediate speeds and a walk–rest mixture at the lowest average speeds is predicted by metabolic energy minimization, even with costs for transients—a consequence of non-convex energy curves. Thus, sometimes, steady locomotion may not be energy optimal, and not preferred, even in the absence of fatigue. Assuming similar non-convex energy curves, we conjecture that similar walk–run mixtures may be energetically beneficial to children following a parent and animals on long leashes. Humans and other animals might also benefit energetically from alternating between moving forward and standing still on a slow and sufficiently long treadmill. PMID:23365192

  19. Evaluating near highway air pollutant levels and estimating emission factors: Case study of Tehran, Iran.

    PubMed

    Nayeb Yazdi, Mohammad; Delavarrafiee, Maryam; Arhami, Mohammad

    2015-12-15

    A field sampling campaign was implemented to evaluate the variation in air pollutants levels near a highway in Tehran, Iran (Hemmat highway). The field measurements were used to estimate road link-based emission factors for average vehicle fleet. These factors were compared with results of an in tunnel measurement campaign (in Resalat tunnel). Roadside and in-tunnel measurements of carbon monoxide (CO) and size-fractionated particulate matter (PM) were conducted during the field campaign. The concentration gradient diagrams showed exponential decay, which represented a substantial decay, more than 50-80%, in air pollutants level in a distance between 100 and 150meters (m) of the highway. The changes in particle size distribution by distancing from highway were also captured and evaluated. The results showed particle size distribution shifted to larger size particles by distancing from highway. The empirical emission factors were obtained by using the roadside and in tunnel measurements with a hypothetical box model, floating machine model, CALINE4, CT-EMFAC or COPERT. Average CO emission factors were estimated to be in a range of 4 to 12g/km, and those of PM10 were 0.1 to 0.2g/km, depending on traffic conditions. Variations of these emission factors under real working condition with speeds were determined. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Divine proportions in attractive and nonattractive faces.

    PubMed

    Pancherz, Hans; Knapp, Verena; Erbe, Christina; Heiss, Anja Melina

    2010-01-01

    To test Ricketts' 1982 hypothesis that facial beauty is measurable by comparing attractive and nonattractive faces of females and males with respect to the presence of the divine proportions. The analysis of frontal view facial photos of 90 cover models (50 females, 40 males) from famous fashion magazines and of 34 attractive (29 females, five males) and 34 nonattractive (13 females, 21 males) persons selected from a group of former orthodontic patients was carried out in this study. Based on Ricketts' method, five transverse and seven vertical facial reference distances were measured and compared with the corresponding calculated divine distances expressed in phi-relationships (f=1.618). Furthermore, transverse and vertical facial disproportion indices were created. For both the models and patients, all the reference distances varied largely from respective divine values. The average deviations ranged from 0.3% to 7.8% in the female groups of models and attractive patients with no difference between them. In the male groups of models and attractive patients, the average deviations ranged from 0.2% to 11.2%. When comparing attractive and nonattractive female, as well as male, patients, deviations from the divine values for all variables were larger in the nonattractive sample. Attractive individuals have facial proportions closer to the divine values than nonattractive ones. In accordance with the hypothesis of Ricketts, facial beauty is measurable to some degree. COPYRIGHT © 2009 BY QUINTESSENCE PUBLISHING CO, INC.

  1. Neutrino emission from nearby supernova progenitors

    NASA Astrophysics Data System (ADS)

    Yoshida, Takashi; Takahashi, Koh; Umeda, Hideyuki

    2016-05-01

    Neutrinos have an important role for energy loss process during advanced evolution of massive stars. Although the luminosity and average energy of neutrinos during the Si burning are much smaller than those of supernova neutrinos, these neutrinos are expected to be detected by the liquid scintillation neutrino detector KamLAND if a supernova explosion occurs at the distance of ~100 parsec. We investigate the neutrino emission from massive stars during advanced evolution. We calculate the evolution of the energy spectra of neutrinos produced through electron-positron pair-annihilation in the supernova progenitors with the initial mass of 12, 15, and 20 M ⊙ during the Si burning and core-collapse stages. The neutrino emission rate increases from ~ 1050 s-1 to ~ 1052 s-1. The average energy of electron-antineutrinos is about 1.25 MeV during the Si burning and gradually increases until the core-collapse. For one week before the supernova explosion, the KamLAND detector is expected to observe 12-24 and 6-13 v¯e events in the normal and inverted mass hierarchies, respectively, if a supernova explosion of a 12-20 M ⊙ star occurs at the distance of 200 parsec, corresponding to the distance to Betelgeuse. Observations of neutrinos from SN progenitors have a possibility to constrain the core structure and the evolution just before the core collapse of massive stars.

  2. Photo-induced morphological winding and unwinding motion of nanoscrolls composed of niobate nanosheets with a polyfluoroalkyl azobenzene derivative

    NASA Astrophysics Data System (ADS)

    Nabetani, Yu; Takamura, Hazuki; Uchikoshi, Akino; Hassan, Syed Zahid; Shimada, Tetsuya; Takagi, Shinsuke; Tachibana, Hiroshi; Masui, Dai; Tong, Zhiwei; Inoue, Haruo

    2016-06-01

    Photo-responsive nanoscrolls can be successfully fabricated by mixing a polyfluoroalkyl azobenzene derivative and a niobate nanosheet, which is exfoliated from potassium hexaniobate. In this study, we have found that the photo-responsive nanoscroll shows a morphological motion of winding and unwinding, which is basically due to the nanosheet sliding within the nanoscroll, by efficient photo-isomerization reactions of the intercalated azobenzene in addition to the interlayer distance change of the nanoscrolls. The relative nanosheet sliding of the nanoscroll is estimated to be ca. 280 nm from the AFM morphology analysis. The distance of the sliding motion is over 20 times that of the averaged nanosheet sliding in the azobenzene/niobate hybrid film reported previously. Photo-responsive nanoscrolls can be expected to be novel photo-activated actuators and artificial muscle model materials.Photo-responsive nanoscrolls can be successfully fabricated by mixing a polyfluoroalkyl azobenzene derivative and a niobate nanosheet, which is exfoliated from potassium hexaniobate. In this study, we have found that the photo-responsive nanoscroll shows a morphological motion of winding and unwinding, which is basically due to the nanosheet sliding within the nanoscroll, by efficient photo-isomerization reactions of the intercalated azobenzene in addition to the interlayer distance change of the nanoscrolls. The relative nanosheet sliding of the nanoscroll is estimated to be ca. 280 nm from the AFM morphology analysis. The distance of the sliding motion is over 20 times that of the averaged nanosheet sliding in the azobenzene/niobate hybrid film reported previously. Photo-responsive nanoscrolls can be expected to be novel photo-activated actuators and artificial muscle model materials. Electronic supplementary information (ESI) available: Fig. S1. Photo-isomerization reaction of nanoscrolls. See DOI: 10.1039/c6nr02177h

  3. Genomic Characterization Helps Dissecting an Outbreak of Listeriosis in Northern Italy.

    PubMed

    Comandatore, Francesco; Corbella, Marta; Andreoli, Giuseppina; Scaltriti, Erika; Aguzzi, Massimo; Gaiarsa, Stefano; Mariani, Bianca; Morganti, Marina; Bandi, Claudio; Fabbi, Massimo; Marone, Piero; Pongolini, Stefano; Sassera, Davide

    2017-07-06

    Listeria monocytogenes (Lm) is a bacterium widely distributed in nature and able to contaminate food processing environments, including those of dairy products. Lm is a primary public health issue, due to the very low infectious dose and the ability to produce severe outcomes, in particular in elderly, newborns, pregnant women and immunocompromised patients. In the period between April and July 2015, an increased number of cases of listeriosis was observed in the area of Pavia, Northern Italy. An epidemiological investigation identified a cheesemaking small organic farm as the possible origin of the outbreak. In this work we present the results of the retrospective epidemiological study that we performed using molecular biology and genomic epidemiology methods. The strains sampled from patients and those from the target farm's cheese were analyzed using PFGE and whole genome sequencing (WGS) based methods. The performed WGS based analyses included: a) in-silico MLST typing; b) SNPs calling and genetic distance evaluation; c) determination of the resistance and virulence genes profiles; d) SNPs based phylogenetic reconstruction. Three of the patient strains and all the cheese strains resulted to belong to the same phylogenetic cluster, in Sequence Type 29. A further accurate SNPs analysis revealed that two of the three patient strains and all the cheese strains were highly similar (0.8 SNPs of average distance) and exhibited a higer distance from the third patient isolate (9.4 SNPs of average distance). Despite the global agreement among the results of the PFGE and WGS epidemiological studies, the latter approach agree with epidemiological data in indicating that one the patient strains could have originated from a different source. This result highlights that WGS methods can allow to better.

  4. Genomic Characterization Helps Dissecting an Outbreak of Listeriosis in Northern Italy

    PubMed Central

    Comandatore, Francesco; Corbella, Marta; Andreoli, Giuseppina; Scaltriti, Erika; Aguzzi, Massimo; Gaiarsa, Stefano; Mariani, Bianca; Morganti, Marina; Bandi, Claudio; Fabbi, Massimo; Marone, Piero; Pongolini, Stefano; Sassera, Davide

    2017-01-01

    Introduction Listeria monocytogenes (Lm) is a bacterium widely distributed in nature and able to contaminate food processing environments, including those of dairy products. Lm is a primary public health issue, due to the very low infectious dose and the ability to produce severe outcomes, in particular in elderly, newborns, pregnant women and immunocompromised patients. Methods In the period between April and July 2015, an increased number of cases of listeriosis was observed in the area of Pavia, Northern Italy. An epidemiological investigation identified a cheesemaking small organic farm as the possible origin of the outbreak. In this work we present the results of the retrospective epidemiological study that we performed using molecular biology and genomic epidemiology methods. The strains sampled from patients and those from the target farm's cheese were analyzed using PFGE and whole genome sequencing (WGS) based methods. The performed WGS based analyses included: a) in-silico MLST typing; b) SNPs calling and genetic distance evaluation; c) determination of the resistance and virulence genes profiles; d) SNPs based phylogenetic reconstruction. Results Three of the patient strains and all the cheese strains resulted to belong to the same phylogenetic cluster, in Sequence Type 29. A further accurate SNPs analysis revealed that two of the three patient strains and all the cheese strains were highly similar (0.8 SNPs of average distance) and exhibited a higer distance from the third patient isolate (9.4 SNPs of average distance). Discussion Despite the global agreement among the results of the PFGE and WGS epidemiological studies, the latter approach agree with epidemiological data in indicating that one the patient strains could have originated from a different source. This result highlights that WGS methods can allow to better PMID:28856063

  5. Costs of Multidisciplinary Parenteral Nutrition Care Provided at a Distance via Mobile Tablets

    PubMed Central

    Kim, Heejung; Spaulding, Ryan; Werkowitch, Marilyn; Yadrich, Donna; Piamjariyakul, Ubolrat; Gilroy, Richard; Smith, Carol E.

    2014-01-01

    Background Determining the costs of healthcare delivery is a key step for providing efficient nutrition-based care. This analysis tabulates the costs of delivering home parenteral nutrition (HPN) interventions and clinical assessments through encrypted mobile technologies to increase patients’ access to healthcare providers, reduce their travel expenses, and allow early detection of infection and other complications. Methods A traditional cost-accounting method was used to tabulate all expenses related to mobile distance HPN clinic appointments, including (1) personnel time of multidisciplinary healthcare professionals, (2) supply of HPN intervention materials, and (3) equipment, connection, and delivery expenses. Results A total of 20 mobile distance clinic appointments were conducted for an average of 56 minutes each with 45 patients who required HPN infusion care. The initial setup costs included mobile tablet devices, 4G data plans, and personnel's time as well as intervention materials. The initial costs were on average $916.64 per patient, while the follow-up clinic appointments required $361.63 a month, with these costs continuing to decline as the equipment was used by multiple patients more frequently over time. Patients reported high levels of satisfaction with cost savings in travel expenses and rated the quality of care comparable to traditional in-person examinations. Conclusion This study provides important aspects of the initial cost tabulation for visual assessment for HPN appointments. These findings will be used to generate a decision algorithm for scheduling mobile distance clinic appointments intermittent with in-person visits to determine how to lower costs of nutrition assessments. To maximize the cost benefits, clinical trials must continue to collect clinical outcomes. PMID:25245253

  6. The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs.

    PubMed

    DuBay, D A; MacLennan, P A; Reed, R D; Fouad, M; Martin, M; Meeks, C B; Taylor, G; Kilgore, M L; Tankersley, M; Gray, S H; White, J A; Eckhoff, D E; Locke, J E

    2015-02-01

    Changes to the liver allocation system have been proposed to decrease regional variation in access to liver transplant. It is unclear what impact these changes will have on cold ischemia times (CITs) and donor transportation costs. Therefore, we performed a retrospective single center study (2008-2012) measuring liver procurement CIT and transportation costs. Four groups were defined: Local-within driving distance (Local-D, n = 262), Local-flight (Local-F, n = 105), Regional-flight <3 h (Regional <3 h, n = 61) and Regional-Flight >3 h (Regional >3 h, n = 53). The median travel distance increased in each group, varying from zero miles (Local-D), 196 miles (Local-F), 384 miles (Regional <3 h), to 1647 miles (Regional >3 h). Increasing travel distances did not significantly increase CIT until the flight time was >3 h. The average CIT ranged from 5.0 to 6.0 h for Local-D, Local-F and Regional <3 h, but increased to 10 h for Regional >3 h (p < 0.0001). Transportation costs increased with greater distance traveled: Local-D $101, Local-F $1993, Regional <3 h $8324 and Regional >3 h $27 810 (p < 0.0001). With proposed redistricting, local financial modeling suggests that the average liver donor procurement transportation variable direct costs will increase from $2415 to $7547/liver donor, an increase of 313%. These findings suggest that further discussion among transplant centers and insurance providers is needed prior to policy implementation. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

  7. Characteristics of interplanetary type II radio emission and the relationship to shock and plasma properties

    NASA Technical Reports Server (NTRS)

    Lengyel-Frey, D.; Stone, R. G.

    1989-01-01

    A large sample of type II events is the basis of the present study of the properties of interplanetary type II bursts' radio-emission properties. Type II spectra seem to be composed of fundamental and harmonic components of plasma emission, where the intensity of the fundamental component increases relative to the harmonic as the burst evolves with heliocentric distance; burst average flux density increases as a power of the associated shock's average velocity. Solar wind density structures may have a significant influence on type II bandwidths.

  8. CLUSFAVOR 5.0: hierarchical cluster and principal-component analysis of microarray-based transcriptional profiles

    PubMed Central

    Peterson, Leif E

    2002-01-01

    CLUSFAVOR (CLUSter and Factor Analysis with Varimax Orthogonal Rotation) 5.0 is a Windows-based computer program for hierarchical cluster and principal-component analysis of microarray-based transcriptional profiles. CLUSFAVOR 5.0 standardizes input data; sorts data according to gene-specific coefficient of variation, standard deviation, average and total expression, and Shannon entropy; performs hierarchical cluster analysis using nearest-neighbor, unweighted pair-group method using arithmetic averages (UPGMA), or furthest-neighbor joining methods, and Euclidean, correlation, or jack-knife distances; and performs principal-component analysis. PMID:12184816

  9. Design and Implementation of Pointer-Type Multi Meters Intelligent Recognition Device Based on ARM Platform

    NASA Astrophysics Data System (ADS)

    Cui, Yang; Luo, Wang; Fan, Qiang; Peng, Qiwei; Cai, Yiting; Yao, Yiyang; Xu, Changfu

    2018-01-01

    This paper adopts a low power consumption ARM Hisilicon mobile processing platform and OV4689 camera, combined with a new skeleton extraction based on distance transform algorithm and the improved Hough algorithm for multi meters real-time reading. The design and implementation of the device were completed. Experimental results shows that The average error of measurement was 0.005MPa, and the average reading time was 5s. The device had good stability and high accuracy which meets the needs of practical application.

  10. Seismic Study of the Dynamics of the Solar Subsurface from SoHO Observations

    NASA Technical Reports Server (NTRS)

    Korzennik, Sylvain G.; Wagner, William J. (Technical Monitor)

    2001-01-01

    In collaboration with Dr. Baudin, we have developed and refined the new observational methodology for local helioseismology known as time-distance analysis. Global helioseismology study the solar oscillations as a superposition of resonant modes, whose properties (mode frequencies) reflect the global structure of the sun (sound speed stratification, rotation rate, etc). In contrast, local helioseismology look at the solar oscillations as wave packets whose propagation will be affected by perturbations of the media sampled. These local perturbations (sound speed or velocity flows) will modify the propagation time, that in turn can be used as a diagnostic tool for a given region. From a data reduction perspective, the processing of solar dopplergrams that result in time-distance maps, i.e. propagation times as a function of distance between bounces at the surface, is radically different from the methodology used for global mode analysis. We have, in a first step, further develop the programs needed to carry out such analysis. We have then applied them to NMI data set, and explore the trade-off between various averaging and filtering approaches - steps required to improve the signal-to-noise ratio of correlation maps - and the resulting stability and precision of the fitted propagation times. While excessive averaging (whether over space, propagation distance, or time) will reduce the diagnostic potential of the method, insufficient averaging lead to unstable fits, or uncertainties so large as to hide the information we seek. In a second phase, we have developed the analysis methodology required to infer local properties from perturbation in time propagation. Namely, we have developed time-distance inversion techniques, with an emphasis on inferences of velocity flows from time anomalies. Note also that during the period covered by this grant, all the investigators on this proposal (i.e., Drs. Baudin, Eff-Darwich, Korzennik, and Noyes) took part in the organization of the SOHO 6 /GONG 99 Workshop: Structure and Dynamics of the Interior of the Sun and Sunlike Stars, held on June 1-4 1999 at the Boston Park Plaza Hotel in Boston, Massachusetts, USA. it was very well attended by more than 160 participants from 26 countries from all over the world. The proceedings were published in two volumes as ESA SP-418, with Sessions I-III in Volume 1, and Sessions IV-VI in Volume 2 (1,000 pages in total). The complete contents are also included in digital form on a CD-ROM included with Volume 1. This CD-ROM also contains additional multi-media material that complements some of the contributions.

  11. Development of a distance-to-roadway proximity metric to compare near-road pollutant levels to a central site monitor

    NASA Astrophysics Data System (ADS)

    Barzyk, Timothy M.; George, Barbara Jane; Vette, Alan F.; Williams, Ronald W.; Croghan, Carry W.; Stevens, Carvin D.

    The primary objective of the Detroit Exposure and Aerosol Research Study (DEARS) was to compare air pollutant concentrations measured at various neighborhoods, or exposure monitoring areas (EMAs), throughout a major metropolitan area to levels measured at a central site or community monitor. One of the EMAs was located near a busy freeway (annual average daily traffic (AADT) of ˜130,000) so that impacts of mobile sources could be examined. Air pollution concentrations from the roadway-proximate sites were compared to the central site monitor. The volatile organic compounds (VOCs) selected (benzene, toluene, ethylbenzene, m,p- and o-xylene, 1,3 butadiene, 1,3,5-trimethylbenzene and 4-ethyltoluene) are typically associated with mobile sources. Gradients were also evident that demonstrated the amplification of pollutant levels near the roadway compared to the community monitor. A novel distance-to-roadway proximity metric was developed to plot the measurements and model these gradients. Effective distance represents the actual distance an air parcel travels from the middle of a roadway to a site and varies as a function of wind direction, whereas perpendicular distance is a fixed distance oriented normal to the roadway. Perpendicular distance is often used as a proxy for exposures to traffic emissions in epidemiological studies. Elevated concentrations of all the compounds were found for both a summer and winter season. Effective distance was found to be a statistically significant ( p < 0.05) univariate predictor for concentrations of toluene, ethylbenzene, m,p-xylene and o-xylene for summer 2005. For each of these pollutants, effective distance yielded lower p-values than the corresponding perpendicular distance models, and model fit improved. Results demonstrate that this near-road EMA had elevated levels of traffic-related VOCs compared to the community monitor, and that effective distance was a more accurate predictor of the degree to which they were elevated as a function of distance. Effective distance produced a range of distance-to-roadway values for a single site based on wind direction, thus increasing the number and range of values that could be used to plot and predict relative differences in pollutant concentrations between two sites.

  12. Walking Behavior of Zoo Elephants: Associations between GPS-Measured Daily Walking Distances and Environmental Factors, Social Factors, and Welfare Indicators

    PubMed Central

    Holdgate, Matthew R.; Meehan, Cheryl L.; Hogan, Jennifer N.; Miller, Lance J.; Soltis, Joseph; Andrews, Jeff; Shepherdson, David J.

    2016-01-01

    Research with humans and other animals suggests that walking benefits physical health. Perhaps because these links have been demonstrated in other species, it has been suggested that walking is important to elephant welfare, and that zoo elephant exhibits should be designed to allow for more walking. Our study is the first to address this suggestion empirically by measuring the mean daily walking distance of elephants in North American zoos, determining the factors that are associated with variations in walking distance, and testing for associations between walking and welfare indicators. We used anklets equipped with GPS data loggers to measure outdoor daily walking distance in 56 adult female African (n = 33) and Asian (n = 23) elephants housed in 30 North American zoos. We collected 259 days of data and determined associations between distance walked and social, housing, management, and demographic factors. Elephants walked an average of 5.3 km/day with no significant difference between species. In our multivariable model, more diverse feeding regimens were correlated with increased walking, and elephants who were fed on a temporally unpredictable feeding schedule walked 1.29 km/day more than elephants fed on a predictable schedule. Distance walked was also positively correlated with an increase in the number of social groupings and negatively correlated with age. We found a small but significant negative correlation between distance walked and nighttime Space Experience, but no other associations between walking distances and exhibit size were found. Finally, distance walked was not related to health or behavioral outcomes including foot health, joint health, body condition, and the performance of stereotypic behavior, suggesting that more research is necessary to determine explicitly how differences in walking may impact elephant welfare. PMID:27414411

  13. Walking Behavior of Zoo Elephants: Associations between GPS-Measured Daily Walking Distances and Environmental Factors, Social Factors, and Welfare Indicators.

    PubMed

    Holdgate, Matthew R; Meehan, Cheryl L; Hogan, Jennifer N; Miller, Lance J; Soltis, Joseph; Andrews, Jeff; Shepherdson, David J

    2016-01-01

    Research with humans and other animals suggests that walking benefits physical health. Perhaps because these links have been demonstrated in other species, it has been suggested that walking is important to elephant welfare, and that zoo elephant exhibits should be designed to allow for more walking. Our study is the first to address this suggestion empirically by measuring the mean daily walking distance of elephants in North American zoos, determining the factors that are associated with variations in walking distance, and testing for associations between walking and welfare indicators. We used anklets equipped with GPS data loggers to measure outdoor daily walking distance in 56 adult female African (n = 33) and Asian (n = 23) elephants housed in 30 North American zoos. We collected 259 days of data and determined associations between distance walked and social, housing, management, and demographic factors. Elephants walked an average of 5.3 km/day with no significant difference between species. In our multivariable model, more diverse feeding regimens were correlated with increased walking, and elephants who were fed on a temporally unpredictable feeding schedule walked 1.29 km/day more than elephants fed on a predictable schedule. Distance walked was also positively correlated with an increase in the number of social groupings and negatively correlated with age. We found a small but significant negative correlation between distance walked and nighttime Space Experience, but no other associations between walking distances and exhibit size were found. Finally, distance walked was not related to health or behavioral outcomes including foot health, joint health, body condition, and the performance of stereotypic behavior, suggesting that more research is necessary to determine explicitly how differences in walking may impact elephant welfare.

  14. Relationship Between Maximum Aerobic Speed Performance and Distance Covered in Rugby Union Games.

    PubMed

    Swaby, Rick; Jones, Paul A; Comfort, Paul

    2016-10-01

    Swaby, R, Jones, PA, and Comfort, P. Relationship between maximum aerobic speed performance and distance covered in rugby union games. J Strength Cond Res 30(10): 2788-2793, 2016-Researchers have shown a clear relationship between aerobic fitness and the distance covered in professional soccer, although no research has identified such a relationship in rugby union. Therefore, the aim of the study was to identify whether there was a relationship between maximal aerobic speed (MAS) and the distance covered in rugby union games. Fourteen professional rugby union players (age = 26 ± 6 years, height = 1.90 ± 0.12 m, mass = 107.1 ± 24.1 kg) participated in this investigation. Each player performed a MAS test on 3 separate occasions during the preseason, to determine reliability and provide baseline data, and participated in 6 competitive games during the early stages of the season. Game data were collected using global positioning system technology. No significant difference (p > 0.05) in total distance covered was observed between games. Relationships between players' MAS and the average distance covered from 6 competitive games were explored using Pearson's correlation coefficients, with MAS performance showing a strong relationship with distance covered during match play (r = 0.746, p < 0.001). Significantly greater (p = 0.001, Cohen's d = 2.29) distances were covered by backs (6,544 ± 573 m) compared with the forwards (4,872 ± 857 m) during a game. Similarly, backs recorded a significantly (p = 0.001, Cohen's d = 2.20) higher MAS (4.9 ± 0.13 m·s) compared with the forwards (4.2 ± 0.43 m·s). Results of the study illustrate the importance of developing high levels of aerobic fitness to increase the distance that the athlete covers in the game.

  15. Correlation of the tibial tuberosity-trochlear groove distance with the Q-angle.

    PubMed

    Dickschas, Jörg; Harrer, Jörg; Bayer, Thomas; Schwitulla, Judith; Strecker, Wolf

    2016-03-01

    The Q-angle has been used for years to quantify lateralization of the patella. The tibial tuberosity-trochlea groove distance (TT-TG distance) was introduced to analyse patellar tracking. Does a significant correlation exist between these two parameters? Do other significant interrelations exist between the Q-angle/TT-TG distance, torsion of the femur and tibia, the frontal axis, overall leg length, gender, former patellar dislocation, BMI? One hundred knees in 55 patients with patellofemoral symptoms were included in a prospective study. All patients underwent clinical examination, including measurement of the Q-angle. A torsional CT was obtained from all patients. The correlation coefficient was 0.33/0.34 (left/right leg), showing that the TT-TG distance tends to rise in direct ratio to a rising Q-angle. Thus, a significant correlation was found (p = 0.017). Femoral and tibial torsion had a positive effect on the TT-TG distance, but showed no significant correlation. Leg length had a significant effect on the TT-TG distance (p = 0.04). The frontal axis had a nonsignificant influence on the Q-angle or TT-TG distance. On average, the Q-angle in women was 2.38° greater than it was in men, but the difference was not significant. A significant correlation was noted between the Q-angle and the TT-TG distance. Both depend on various parameters and must be assessed for the analysis of patellofemoral maltracking. The Q-angle did not differ significantly between men and women; thus, the conclusion is that no different ranges need not be used. Diagnostic study, Level III.

  16. Characteristics of lesser prairie-chicken (Tympanuchus pallidicinctus) long-distance movements across their distribution

    USGS Publications Warehouse

    Earl, Julia E.; Fuhlendorf, Samuel D.; Haukos, David A.; Tanner, Ashley M.; Elmore, Dwayne; Carleton, Scott A.

    2016-01-01

    Long-distance movements are important adaptive behaviors that contribute to population, community, and ecosystem connectivity. However, researchers have a poor understanding of the characteristics of long-distance movements for most species. Here, we examined long-distance movements for the lesser prairie-chicken (Tympanuchus pallidicinctus), a species of conservation concern. We addressed the following questions: (1) At what distances could populations be connected? (2) What are the characteristics and probability of dispersal movements? (3) Do lesser prairie-chickens display exploratory and round-trip movements? (4) Do the characteristics of long-distance movements vary by site? Movements were examined from populations using satellite GPS transmitters across the entire distribution of the species in New Mexico, Oklahoma, Kansas, and Colorado. Dispersal movements were recorded up to 71 km net displacement, much farther than hitherto recorded. These distances suggest that there may be greater potential connectivity among populations than previously thought. Dispersal movements were displayed primarily by females and had a northerly directional bias. Dispersal probabilities ranged from 0.08 to 0.43 movements per year for both sexes combined, although these movements averaged only 16 km net displacement. Lesser prairie-chickens displayed both exploratory foray loops and round-trip movements. Half of round-trip movements appeared seasonal, suggesting a partial migration in some populations. None of the long-distance movements varied by study site. Data presented here will be important in parameterizing models assessing population viability and informing conservation planning, although further work is needed to identify landscape features that may reduce connectivity among populations.

  17. How Do Changes in Speed Affect the Perception of Duration?

    ERIC Educational Resources Information Center

    Matthews, William J.

    2011-01-01

    Six experiments investigated how changes in stimulus speed influence subjective duration. Participants saw rotating or translating shapes in three conditions: constant speed, accelerating motion, and decelerating motion. The distance moved and average speed were the same in all three conditions. In temporal judgment tasks, the constant-speed…

  18. MODELING THE INFLUENCE OF ACTIVE SUBSLAB DEPRESSURIZATION (ASD) SYSTEMS ON AIRFLOWS IN SUBSLAB AGGREGATE BEDS

    EPA Science Inventory

    A simple model is presented that allows the pressure difference in a subslab aggregate layer to be estimated as a function of radial distance from the central suction point of an active subslab depressurization system by knowing the average size, thickness, porosity, and permeabi...

  19. Setting analyst: A practical harvest planning technique

    Treesearch

    Olivier R.M. Halleux; W. Dale Greene

    2001-01-01

    Setting Analyst is an ArcView extension that facilitates practical harvest planning for ground-based systems. By modeling the travel patterns of ground-based machines, it compares different harvesting settings based on projected average skidding distance, logging costs, and site disturbance levels. Setting Analyst uses information commonly available to consulting...

  20. Distance measurements from supernovae and dark energy constraints

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang Yun

    2009-12-15

    Constraints on dark energy from current observational data are sensitive to how distances are measured from Type Ia supernova (SN Ia) data. We find that flux averaging of SNe Ia can be used to test the presence of unknown systematic uncertainties, and yield more robust distance measurements from SNe Ia. We have applied this approach to the nearby+SDSS+ESSENCE+SNLS+HST set of 288 SNe Ia, and the 'Constitution' set of 397 SNe Ia. Combining the SN Ia data with cosmic microwave background anisotropy data from Wilkinson Microwave Anisotropy Probe 5 yr observations, the Sloan Digital Sky Survey baryon acoustic oscillation measurements, themore » data of 69 gamma-ray bursts (GRBs) , and the Hubble constant measurement from the Hubble Space Telescope project SHOES, we measure the dark energy density function X(z){identical_to}{rho}{sub X}(z)/{rho}{sub X}(0) as a free function of redshift (assumed to be a constant at z>1 or z>1.5). Without the flux averaging of SNe Ia, the combined data using the Constitution set of SNe Ia seem to indicate a deviation from a cosmological constant at {approx}95% confidence level at 0 < or apporx. z < or approx. 0.8; they are consistent with a cosmological constant at {approx}68% confidence level when SNe Ia are flux averaged. The combined data using the nearby+SDSS+ESSENCE+SNLS+HST data set of SNe Ia are consistent with a cosmological constant at 68% confidence level with or without flux averaging of SNe Ia, and give dark energy constraints that are significantly more stringent than that using the Constitution set of SNe Ia. Assuming a flat Universe, dark energy is detected at >98% confidence level for z{<=}0.75 using the combined data with 288 SNe Ia from nearby+SDSS+ESSENCE+SNLS+HST, independent of the assumptions about X(z{>=}1). We quantify dark energy constraints without assuming a flat Universe using the dark energy figure of merit for both X(z) and a dark energy equation-of-state linear in the cosmic scale factor.« less

  1. New approaches to spatially analyse primary health care usage patterns in rural South Africa.

    PubMed

    Tanser, F; Hosegood, V; Benzler, J; Solarsh, G

    2001-10-01

    To develop indices to quantitatively assess and understand the spatial usage patterns of health facilities in the Hlabisa district of South Africa. We mapped and interviewed more than 23 000 homesteads (approximately 200 000 people) in Hlabisa district, South Africa and spatially analysed their modal primary health usage patterns using a geographical information system. We generated contour maps of health service use and quantified the relationship between clinic catchments and distance-defined catchments using inclusion and exclusion error. We propose the distance usage index (DUI) as an overall spatial measure of clinic usage. This index is the sum of the distances from clinic to all client homesteads divided by the sum of the distances from clinic to all homesteads within its distance-defined catchment. The index encompasses inclusion, exclusion, and strength of patient attraction for each clinic. Eighty-seven per cent of homesteads use the nearest clinic. Residents of homesteads travel an average Euclidean distance of 4.72 km to attend clinics. There is a significant logarithmic relationship between distance from clinic and their use by homesteads (r(2)=0.774, P < 0.0001). The DUI values range between 31 and 198% (mean=110%, SD=43.7) for 12 clinics and highlight clinic usage patterns across the district. The DUI is a powerful and informative composite measure of clinic usage. The results of the study have important implications for health care provision in developing countries.

  2. Incorporation of physical constraints in optimal surface search for renal cortex segmentation

    NASA Astrophysics Data System (ADS)

    Li, Xiuli; Chen, Xinjian; Yao, Jianhua; Zhang, Xing; Tian, Jie

    2012-02-01

    In this paper, we propose a novel approach for multiple surfaces segmentation based on the incorporation of physical constraints in optimal surface searching. We apply our new approach to solve the renal cortex segmentation problem, an important but not sufficiently researched issue. In this study, in order to better restrain the intensity proximity of the renal cortex and renal column, we extend the optimal surface search approach to allow for varying sampling distance and physical separation constraints, instead of the traditional fixed sampling distance and numerical separation constraints. The sampling distance of each vertex-column is computed according to the sparsity of the local triangular mesh. Then the physical constraint learned from a priori renal cortex thickness is applied to the inter-surface arcs as the separation constraints. Appropriate varying sampling distance and separation constraints were learnt from 6 clinical CT images. After training, the proposed approach was tested on a test set of 10 images. The manual segmentation of renal cortex was used as the reference standard. Quantitative analysis of the segmented renal cortex indicates that overall segmentation accuracy was increased after introducing the varying sampling distance and physical separation constraints (the average true positive volume fraction (TPVF) and false positive volume fraction (FPVF) were 83.96% and 2.80%, respectively, by using varying sampling distance and physical separation constraints compared to 74.10% and 0.18%, respectively, by using fixed sampling distance and numerical separation constraints). The experimental results demonstrated the effectiveness of the proposed approach.

  3. The Near-infrared Optimal Distances Method Applied to Galactic Classical Cepheids Tightly Constrains Mid-infrared Period–Luminosity Relations

    NASA Astrophysics Data System (ADS)

    Wang, Shu; Chen, Xiaodian; de Grijs, Richard; Deng, Licai

    2018-01-01

    Classical Cepheids are well-known and widely used distance indicators. As distance and extinction are usually degenerate, it is important to develop suitable methods to robustly anchor the distance scale. Here, we introduce a near-infrared optimal distance method to determine both the extinction values of and distances to a large sample of 288 Galactic classical Cepheids. The overall uncertainty in the derived distances is less than 4.9%. We compare our newly determined distances to the Cepheids in our sample with previously published distances to the same Cepheids with Hubble Space Telescope parallax measurements and distances based on the IR surface brightness method, Wesenheit functions, and the main-sequence fitting method. The systematic deviations in the distances determined here with respect to those of previous publications is less than 1%–2%. Hence, we constructed Galactic mid-IR period–luminosity (PL) relations for classical Cepheids in the four Wide-Field Infrared Survey Explorer (WISE) bands (W1, W2, W3, and W4) and the four Spitzer Space Telescope bands ([3.6], [4.5], [5.8], and [8.0]). Based on our sample of hundreds of Cepheids, the WISE PL relations have been determined for the first time; their dispersion is approximately 0.10 mag. Using the currently most complete sample, our Spitzer PL relations represent a significant improvement in accuracy, especially in the [3.6] band which has the smallest dispersion (0.066 mag). In addition, the average mid-IR extinction curve for Cepheids has been obtained: {A}W1/{A}{K{{s}}}≈ 0.560, {A}W2/{A}{K{{s}}}≈ 0.479, {A}W3/{A}{K{{s}}}≈ 0.507, {A}W4/{A}{K{{s}}}≈ 0.406, {A}[3.6]/{A}{K{{s}}}≈ 0.481, {A}[4.5]/{A}{K{{s}}}≈ 0.469, {A}[5.8]/{A}{K{{s}}}≈ 0.427, and {A}[8.0]/{A}{K{{s}}}≈ 0.427 {mag}.

  4. Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs

    PubMed Central

    Cunningham, Daniel J.; Shearer, David A.; Carter, Neil; Drawer, Scott; Pollard, Ben; Bennett, Mark; Eager, Robin; Cook, Christian J.; Farrell, John; Russell, Mark

    2018-01-01

    The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5–40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. Accordingly, this study compared rolling average (ROLL) and fixed-time (FIXED) epochs for quantifying the peak movement demands of international rugby union match-play as a function of playing position. Elite players from three different squads (n = 119) were monitored using 10 Hz GPS during 36 matches played in the 2014–2017 seasons. Players categorised broadly as forwards and backs, and then by positional sub-group (FR: front row, SR: second row, BR: back row, HB: half back, MF: midfield, B3: back three) were monitored during match-play for peak values of high-speed running (>5 m·s-1; HSR) and relative distance covered (m·min-1) over 60–300 s using two types of sample-epoch (ROLL, FIXED). Irrespective of the method used, as the epoch length increased, values for the intensity of running actions decreased (e.g., For the backs using the ROLL method, distance covered decreased from 177.4 ± 20.6 m·min-1 in the 60 s epoch to 107.5 ± 13.3 m·min-1 for the 300 s epoch). For the team as a whole, and irrespective of position, estimates of fixed effects indicated significant between-method differences across all time-points for both relative distance covered and HSR. Movement demands were underestimated consistently by FIXED versus ROLL with differences being most pronounced using 60 s epochs (95% CI HSR: -6.05 to -4.70 m·min-1, 95% CI distance: -18.45 to -16.43 m·min-1). For all HSR time epochs except one, all backs groups increased more (p < 0.01) from FIXED to ROLL than the forward groups. Linear mixed modelling of ROLL data highlighted that for HSR (except 60 s epoch), SR was the only group not significantly different to FR. For relative distance covered all other position groups were greater than the FR (p < 0.05). The FIXED method underestimated both relative distance (~11%) and HSR values (up to ~20%) compared to the ROLL method. These differences were exaggerated for the HSR variable in the backs position who covered the greatest HSR distance; highlighting important consideration for those implementing the FIXED method of analysis. The data provides coaches with a worst-case scenario reference on the running demands required for periods of 60–300 s in length. This information offers novel insight into game demands and can be used to inform the design of training games to increase specificity of preparation for the most demanding phases of matches. PMID:29621279

  5. Relationships between weekly walking distance and adiposity in27,596 women are nonlinear with respect to both distance andadiposity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Paul T.

    2004-12-01

    The cross-sectional relationships of weekly walking distance to BMI, body circumferences, and bra cup sizes are reported for 27,596 women. The percent reductions between walking 40-50 km/wk and < 10km/wk were greatest for BMI, substantial for waist circumference and cupsize, and least for hip and chest circumferences. The relationships between distance and adiposity were nonlinear with respect to both the independent (quadratic function of distance) and dependent variables(slope and curvilinearity depending upon the percentile of BMI, circumference, or cup size). The slope relating adiposity to km/wk were greatest (most negative) in overweight sedentary women and least in lean active women.more » For example, compared to women averaging 10 km/wk, the slope of BMI versus km/wk was 43 percent less at 25 km/wk and 87 percent less at 40 km/wk in overweight women (95th BMI percentile), but negligible at all distances in lean women (5th BMI percentile). The greater estimated decrease in BMI per km/wk in walkers than runners was largely accounted for (over 75 percent) by the walkers greater adiposity. Thus classical representations of the relationship between adiposity and moderate physical activity are inadequate for either statistical analyses or descriptive purposes. The clinical implications of these results and their statistical ramifications are discussed.« less

  6. PREDICTING GAIA’S PARALLAX DISTANCE TO THE CYGNUS OB2 ASSOCIATION WITH ECLIPSING BINARIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kiminki, Daniel C.; Kobulnicky, Henry A.; Álvarez, Carlos A. Vargas

    2015-10-01

    The Cygnus OB2 Association is one of the nearest and largest collections of massive stars in the Galaxy. Situated at the heart of the “Cygnus X” complex of star-forming regions and molecular clouds, its distance has proven elusive owing to the ambiguous nature of kinematic distances along this ℓ ≃ 80° sightline and the heavy, patchy extinction. In an effort to refine the three-dimensional geometry of key Cygnus X constituents, we have measured distances to four eclipsing double-lined OB-type spectroscopic binaries that are probable members of Cyg OB2. We find distances of 1.33 ± 0.17, 1.32 ± 0.07, 1.44 ±more » 0.18, and 1.32 ± 0.13 kpc toward MT91 372, MT91 696, CPR2002 A36, and Schulte 3, respectively. We adopt a weighted average distance of 1.33 ± 0.06 kpc. This agrees well with spectrophotometric estimates for the Association as a whole and with parallax measurements of protostellar masers in the surrounding interstellar clouds, thereby linking the ongoing star formation in these clouds with Cyg OB2. We also identify Schulte 3C (O9.5V), a 4″ visual companion to the 4.75 day binary Schulte 3(A+B), as a previously unrecognized Association member.« less

  7. Inter-rater Reliability of Real-Time Ultrasound to Measure Acromiohumeral Distance.

    PubMed

    Mackenzie, Tanya Anne; Bdaiwi, Alya H; Herrington, Lee; Cools, Ann

    2016-07-01

    Real-time ultrasound (RTUS) has been suggested as a reliable measure of acromiohumeral distance. However, to date, no vigorous assessment and reporting of inter-rater reliability of this method has been performed with the shoulder in a neutral position or with active and passive arm abduction. To assess intrasession inter-rater reliability of using RTUS to measure acromiohumeral distance with the shoulder in a neutral position and with 60° active and passive abduction. Inter-rater intrasession reliability of repeated measures. Human performance laboratory. Twenty persons (12 male and 8 female) with an average age of 29.86 years (standard deviation, 7.8). In an inter-rater, intrasession study, RTUS was used to measure the acromiohumeral distance with the shoulder in a neutral position and with 60° of both active and passive abduction. Acromiohumeral distance. Intraclass correlation coefficient (ICC)2.1 scores ranged between 0.65-0.88 (standard error of the mean = 0.81-1.2 mm and minimal detectable differences with 95% confidence = 2.2-2.3 mm) for inter-rater intrasession reliability. RTUS was found to have fair to good inter-rater reliability as a tool to measure acromiohumeral distance with the shoulder in a neutral position and with 60° of both active and passive arm abduction. Copyright © 2016 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  8. Spatial variability in airborne pollen concentrations.

    PubMed

    Raynor, G S; Ogden, E C; Hayes, J V

    1975-03-01

    Tests were conducted to determine the relationship between airborne pollen concentrations and distance. Simultaneous samples were taken in 171 tests with sets of eight rotoslide samplers spaced from one to 486 M. apart in straight lines. Use of all possible pairs gave 28 separation distances. Tests were conducted over a 2-year period in urban and rural locations distant from major pollen sources during both tree and ragweed pollen seasons. Samples were taken at a height of 1.5 M. during 5-to 20-minute periods. Tests were grouped by pollen type, location, year, and direction of the wind relative to the line. Data were analyzed to evaluate variability without regard to sampler spacing and variability as a function of separation distance. The mean, standard deviation, coefficient of variation, ratio of maximum to the mean, and ratio of minimum to the mean were calculated for each test, each group of tests, and all cases. The average coefficient of variation is 0.21, the maximum over the mean, 1.39 and the minimum over the mean, 0.69. No relationship was found with experimental conditions. Samples taken at the minimum separation distance had a mean difference of 18 per cent. Differences between pairs of samples increased with distance in 10 of 13 groups. These results suggest that airborne pollens are not always well mixed in the lower atmosphere and that a sample becomes less representative with increasing distance from the sampling location.

  9. A reliable DNA barcode reference library for the identification of the North European shelf fish fauna.

    PubMed

    Knebelsberger, Thomas; Landi, Monica; Neumann, Hermann; Kloppmann, Matthias; Sell, Anne F; Campbell, Patrick D; Laakmann, Silke; Raupach, Michael J; Carvalho, Gary R; Costa, Filipe O

    2014-09-01

    Valid fish species identification is an essential step both for fundamental science and fisheries management. The traditional identification is mainly based on external morphological diagnostic characters, leading to inconsistent results in many cases. Here, we provide a sequence reference library based on mitochondrial cytochrome c oxidase subunit I (COI) for a valid identification of 93 North Atlantic fish species originating from the North Sea and adjacent waters, including many commercially exploited species. Neighbour-joining analysis based on K2P genetic distances formed nonoverlapping clusters for all species with a ≥99% bootstrap support each. Identification was successful for 100% of the species as the minimum genetic distance to the nearest neighbour always exceeded the maximum intraspecific distance. A barcoding gap was apparent for the whole data set. Within-species distances ranged from 0 to 2.35%, while interspecific distances varied between 3.15 and 28.09%. Distances between congeners were on average 51-fold higher than those within species. The validation of the sequence library by applying BOLDs barcode index number (BIN) analysis tool and a ranking system demonstrated high taxonomic reliability of the DNA barcodes for 85% of the investigated fish species. Thus, the sequence library presented here can be confidently used as a benchmark for identification of at least two-thirds of the typical fish species recorded for the North Sea. © 2014 John Wiley & Sons Ltd.

  10. Sublimation rates of carbon monoxide and carbon dioxide from comets at large heliocentric distances

    NASA Technical Reports Server (NTRS)

    Sekanina, Zdenek

    1992-01-01

    Using a simple model for outgassing from a small flat surface area, the sublimation rates of carbon monoxide and carbon dioxide, two species more volatile than water ice that are known to be present in comets, are calculated for a suddenly activated discrete source on the rotating nucleus. The instantaneous sublimation rate depends upon the comet's heliocentric distance and the Sun's zenith angle at the location of the source. The values are derived for the constants of CO and CO2 in an expression that yields the local rotation-averaged sublimation rate as a function of the comet's spin parameters and the source's cometocentric latitude.

  11. Robust state transfer in the quantum spin channel via weak measurement and quantum measurement reversal

    NASA Astrophysics Data System (ADS)

    He, Zhi; Yao, Chunmei; Zou, Jian

    2013-10-01

    Using the weak measurement (WM) and quantum measurement reversal (QMR) approach, robust state transfer and entanglement distribution can be realized in the spin-(1)/(2) Heisenberg chain. We find that the ultrahigh fidelity and long distance of quantum state transfer with certain success probability can be obtained using proper WM and QMR, i.e., the average fidelity of a general pure state from 80% to almost 100%, which is almost size independent. We also find that the distance and quality of entanglement distribution for the Bell state and the general Werner mixed state can be obviously improved by the WM and QMR approach.

  12. Further We Travel the Faster We Go

    PubMed Central

    Varga, Levente; Kovács, András; Tóth, Géza; Papp, István; Néda, Zoltán

    2016-01-01

    The average travelling speed increases in a nontrivial manner with the travel distance. This leads to scaling-like relations on quite extended spatial scales, for all mobility modes taken together and also for a given mobility mode in part. We offer a wide range of experimental results, investigating and quantifying this universal effect and its measurable causes. The increasing travelling speed with the travel distance arises from the combined effects of: choosing the most appropriate travelling mode; the structure of the travel networks; the travel times lost in the main hubs, starting or target cities; and the speed limit of roads and vehicles. PMID:26863605

  13. Fabrication of gradient optical filter containing anisotropic Bragg nanostructure.

    PubMed

    Cho, Bomin; Um, Sungyong; Woo, Hee-Gweon; Sohn, Honglae

    2011-08-01

    New gradient optical filters containing asymmetric Bragg structure were prepared from the distributed Bragg reflector (DBR) porous silicon (PSi). Anisotropic DBR PSi displaying a rainbow-colored reflection was generated by using an asymmetric etching configuration. Flexible anisotropic DBR PSi composite films were obtained by casting of polymer solution onto anisotropic DBR PSi thin films. The surface and cross-sectional images images of anisotropic DBR PSi composite films obtained with cold field emission scanning electron microscope indicated that the average pore size and the thickness of porous layer decreased as the lateral distance increased. As lateral distance increased, the reflection resonance shifted to shorter wavelength.

  14. A minimum distance estimation approach to the two-sample location-scale problem.

    PubMed

    Zhang, Zhiyi; Yu, Qiqing

    2002-09-01

    As reported by Kalbfleisch and Prentice (1980), the generalized Wilcoxon test fails to detect a difference between the lifetime distributions of the male and female mice died from Thymic Leukemia. This failure is a result of the test's inability to detect a distributional difference when a location shift and a scale change exist simultaneously. In this article, we propose an estimator based on the minimization of an average distance between two independent quantile processes under a location-scale model. Large sample inference on the proposed estimator, with possible right-censorship, is discussed. The mouse leukemia data are used as an example for illustration purpose.

  15. Department of the Air Force Environmental Statement. Construction and Operation of the West Coast OTH-B Radar System, Lake and Klamath Counties, Oregon; Modoc and Sacramento Counties, California; Pierce County, Washington; Elmore County, Idaho

    DTIC Science & Technology

    1984-02-01

    readily available. EXCEPTION: In the past decade, the Glenns Ferry, Hammett , Grandview, Bruneau, and Boise areas being within an hour or less driving...density, the exclusion fence would be located at a distance where the power density would not exceed 0.1 mW/cm2 . Consistent with Equation 19 on the...distances between 250 and 1,500 ft (per Equation 3, p. B-7). These values imply averaging over substantial periods of time, whereas individuals in aircraft

  16. Americas from the Moon

    NASA Image and Video Library

    2010-09-15

    The western hemisphere of our home planet Earth. North (upper left), Central, and South America (lower right) were nicely free of clouds when LRO pointed home on 9 August 2010 to acquire this beautiful view. LROC NAC E136013771. As LRO orbits the Moon every two hours sending down a stream of science data, it is easy to forget how close the Moon is to the Earth. The average distance between the two heavenly bodies is just 384,399 km (238,854 miles). Check your airline frequent flyer totals, perhaps you have already flown the distance to the Moon and back on a single airline. http://photojournal.jpl.nasa.gov/catalog/PIA13519

  17. Accuracy of assessing the level of impulse sound from distant sources.

    PubMed

    Wszołek, Tadeusz; Kłaczyński, Maciej

    2007-01-01

    Impulse sound events are characterised by ultra high pressures and low frequencies. Lower frequency sounds are generally less attenuated over a given distance in the atmosphere than higher frequencies. Thus, impulse sounds can be heard over greater distances and will be more affected by the environment. To calculate a long-term average immission level it is necessary to apply weighting factors like the probability of the occurrence of each weather condition during the relevant time period. This means that when measuring impulse noise at a long distance it is necessary to follow environmental parameters in many points along the way sound travels and also to have a database of sound transfer functions in the long term. The paper analyses the uncertainty of immission measurement results of impulse sound from cladding and destroying explosive materials. The influence of environmental conditions on the way sound travels is the focus of this paper.

  18. Estimating Genomic Distance from DNA Sequence Location in Cell Nuclei by a Random Walk Model

    NASA Astrophysics Data System (ADS)

    van den Engh, Ger; Sachs, Rainer; Trask, Barbara J.

    1992-09-01

    The folding of chromatin in interphase cell nuclei was studied by fluorescent in situ hybridization with pairs of unique DNA sequence probes. The sites of DNA sequences separated by 100 to 2000 kilobase pairs (kbp) are distributed in interphase chromatin according to a random walk model. This model provides the basis for calculating the spacing of sequences along the linear DNA molecule from interphase distance measurements. An interphase mapping strategy based on this model was tested with 13 probes from a 4-megabase pair (Mbp) region of chromosome 4 containing the Huntington disease locus. The results confirmed the locations of the probes and showed that the remaining gap in the published maps of this region is negligible in size. Interphase distance measurements should facilitate construction of chromosome maps with an average marker density of one per 100 kbp, approximately ten times greater than that achieved by hybridization to metaphase chromosomes.

  19. The Carnegie Hubble Program: The Distance and Structure of the SMC as Revealed by Mid-Infrared Observations of Cepheids

    NASA Technical Reports Server (NTRS)

    Scowcroft, Victoria; Freedman, Wendy L.; Madore, Barry F.; Monson, Andy; Persson, S. E.; Rich, Jeff; Seibert, Mark; Rigby, Jane R.

    2016-01-01

    Using Spitzer observations of classical Cepheids we have measured the true average distance modulus of the Small Magellanic Cloud (SMC) to be18.96 +/- 0.01 stat +/- 0.03sys mag (corresponding to 62+/- 0.3kpc), which is 0.48 +/- 0.01 mag more distant than the LMC. This is in agreement with previous results from Cepheid observations, as well as with measurements from other indicators such as RR Lyrae stars and the tip of the red giant branch. Utilizing the properties of the mid-infrared Leavitt Law we measured precise distances to individual Cepheids in the SMC, and have confirmed that the galaxy is tilted and elongated such that its eastern side is up to20 kpc closer than its western side. This is in agreement with the results from red clump stars and dynamical simulations of the Magellanic Clouds and Stream.

  20. Connecting the hadron mass scale to the fundamental mass scale of quantum chromodynamics

    DOE PAGES

    Deur, Alexandre; Brodsky, Stanley J.; de Teramond, Guy F.

    2015-10-01

    We establish an explicit connection between the long distance physics of confinement and the dynamical interactions of quarks and gluons at short distances and it has been a long-sought goal of quantum chromodynamics. Using holographic QCD, we derive a direct analytic relation between the scale κ which determines the masses of hadrons and the scale Λ s which controls the predictions of perturbative QCD at very short distances. The resulting prediction Λ s=0.341±0.032 GeV in the MS -scheme agrees well with the experimental average 0.339±0.016 GeV. We also derive a relation between Λs and the QCD string tension σ. Furthermore,more » this connection between the fundamental hadronic scale underlying the physics of quark confinement and the perturbative QCD scale controlling hard collisions can be carried out in any renormalization scheme.« less

  1. Analysis of the Variation of Energetic Electron Flux with Respect to Longitude and Distance Normal to the Magnetic Equatorial Plane for Galileo Energetic Particle Detector Data

    NASA Technical Reports Server (NTRS)

    Swimm, Randall; Garrett, Henry B.; Jun, Insoo; Evans, Robin W.

    2004-01-01

    In this study we examine ten-minute omni-directional averages of energetic electron data measured by the Galileo spacecraft Energetic Particle Detector (EPD). Count rates from electron channels B1, DC2, and DC3 are evaluated using a power law model to yield estimates of the differential electron fluxes from 1 MeV to 11 MeV at distances between 8 and 51 Jupiter radii. Whereas the orbit of the Galileo spacecraft remained close to the rotational equatorial plane of Jupiter, the approximately 11 degree tilt of the magnetic axis of Jupiter relative to its rotational axis allowed the EPD instrument to sample high energy electrons at limited distances normal to the magnetic equatorial plane. We present a Fourier analysis of the semi-diurnal variation of electron fluxes with longitude.

  2. Genetic mapping and identification of QTL for earliness in the globe artichoke/cultivated cardoon complex.

    PubMed

    Portis, Ezio; Scaglione, Davide; Acquadro, Alberto; Mauromicale, Giovanni; Mauro, Rosario; Knapp, Steven J; Lanteri, Sergio

    2012-05-23

    The Asteraceae species Cynara cardunculus (2n = 2x = 34) includes the two fully cross-compatible domesticated taxa globe artichoke (var. scolymus L.) and cultivated cardoon (var. altilis DC). As both are out-pollinators and suffer from marked inbreeding depression, linkage analysis has focussed on the use of a two way pseudo-test cross approach. A set of 172 microsatellite (SSR) loci derived from expressed sequence tag DNA sequence were integrated into the reference C. cardunculus genetic maps, based on segregation among the F1 progeny of a cross between a globe artichoke and a cultivated cardoon. The resulting maps each detected 17 major linkage groups, corresponding to the species' haploid chromosome number. A consensus map based on 66 co-dominant shared loci (64 SSRs and two SNPs) assembled 694 loci, with a mean inter-marker spacing of 2.5 cM. When the maps were used to elucidate the pattern of inheritance of head production earliness, a key commercial trait, seven regions were shown to harbour relevant quantitative trait loci (QTL). Together, these QTL accounted for up to 74% of the overall phenotypic variance. The newly developed consensus as well as the parental genetic maps can accelerate the process of tagging and eventually isolating the genes underlying earliness in both the domesticated C. cardunculus forms. The largest single effect mapped to the same linkage group in each parental maps, and explained about one half of the phenotypic variance, thus representing a good candidate for marker assisted selection.

  3. Measures of lexical distance between languages

    NASA Astrophysics Data System (ADS)

    Petroni, Filippo; Serva, Maurizio

    2010-06-01

    The idea of measuring distance between languages seems to have its roots in the work of the French explorer Dumont D’Urville (1832) [13]. He collected comparative word lists for various languages during his voyages aboard the Astrolabe from 1826 to 1829 and, in his work concerning the geographical division of the Pacific, he proposed a method for measuring the degree of relation among languages. The method used by modern glottochronology, developed by Morris Swadesh in the 1950s, measures distances from the percentage of shared cognates, which are words with a common historical origin. Recently, we proposed a new automated method which uses the normalized Levenshtein distances among words with the same meaning and averages on the words contained in a list. Recently another group of scholars, Bakker et al. (2009) [8] and Holman et al. (2008) [9], proposed a refined version of our definition including a second normalization. In this paper we compare the information content of our definition with the refined version in order to decide which of the two can be applied with greater success to resolve relationships among languages.

  4. Wound ballistic evaluation of the Taser® XREP ammunition.

    PubMed

    Kunz, Sebastian N; Adamec, Jiri; Zinka, Bettina; Münzel, Daniela; Noël, Peter B; Eichner, Simon; Manthei, Axel; Grove, Nico; Graw, M; Peschel, Oliver

    2013-01-01

    The Taser® eXtended Range Electronic Projectile (XREP®) is a wireless conducted electrical weapon (CEW) designed to incapacitate a person from a larger distance. The aim of this study was to analyze the ballistic injury potential of the XREP. Twenty rounds were fired from the Taser®X12 TM shotgun into ballistic soap covered with artificial skin and clothing at different shooting distances (1-25 m). One shot was fired at pig skin at a shooting distance of 10 m. The average projectile velocity was 67.0 m/s. The kinetic energy levels on impact varied from 28-52 J. Depending on the intermediate target, the projectiles penetrated up to 4.2 cm into the ballistic soap. On impact the nose assembly did not separate from the chassis, and no electrical activation was registered. Upon impact, a skin penetration of the XREP cannot be excluded. However, it is very unlikely at shooting distances of 10 m or more. Clothing and a high elasticity limit of the target body area can significantly reduce the penetration risk on impact.

  5. Reference equation for prediction of a total distance during six-minute walk test using Indonesian anthropometrics.

    PubMed

    Nusdwinuringtyas, Nury; Widjajalaksmi; Yunus, Faisal; Alwi, Idrus

    2014-04-01

    to develop a reference equation for prediction of the total distance walk using Indonesian anthropometrics of sedentary healthy subjects. Subsequently, the prediction obtained was compared to those calculated by the Caucasian-based Enright prediction equation. the cross-sectional study was conducted among 123 healthy Indonesian adults with sedentary life style (58 male and 65 female subjects in an age range between 18 and 50 years). Heart rate was recorded using Polar with expectation in the sub-maximal zone (120-170 beats per minute). The subjects performed two six-minute walk tests, the first one on a 15-meter track according to the protocol developed by the investigator. The second walk was carried out on Biodex®gait trainer as gold standard. an average total distance of 547±54.24 m was found, not significantly different from the gold standard of 544.72±54.11 m (p>0.05). Multiple regression analysis was performed to develop the new equation. the reference equation for prediction of the total distance using Indonesian anthropometrics is more applicable in Indonesia.

  6. Ultrasound monitoring of inter-knee distances during gait.

    PubMed

    Lai, Daniel T H; Wrigley, Tim V; Palaniswami, M

    2009-01-01

    Knee osteoarthritis is an extremely common, debilitating disease associated with pain and loss of function. There is considerable interest in monitoring lower limb alignment due to its close association with joint overload leading to disease progression. The effects of gait modifications that can lower joint loading are of particular interest. Here we describe an ultrasound-based system for monitoring an important aspect of dynamic lower limb alignment, the inter-knee distance during walking. Monitoring this gait parameter should facilitate studies in reducing knee loading, a primary risk factor of knee osteoarthritis progression. The portable device is composed of an ultrasound sensor connected to an Intel iMote2 equipped with Bluetooth wireless capability. Static tests and calibration results show that the sensor possesses an effective beam envelope of 120 degrees, with maximum distance errors of 10% at the envelope edges. Dynamic walking trials reveal close correlation of inter-knee distance trends between that measured by an optical system (Optotrak Certus NDI) and the sensor device. The maximum average root mean square error was found to be 1.46 cm. Future work will focus on improving the accuracy of the device.

  7. Influence of scanning parameters on the estimation accuracy of control points of B-spline surfaces

    NASA Astrophysics Data System (ADS)

    Aichinger, Julia; Schwieger, Volker

    2018-04-01

    This contribution deals with the influence of scanning parameters like scanning distance, incidence angle, surface quality and sampling width on the average estimated standard deviations of the position of control points from B-spline surfaces which are used to model surfaces from terrestrial laser scanning data. The influence of the scanning parameters is analyzed by the Monte Carlo based variance analysis. The samples were generated for non-correlated and correlated data, leading to the samples generated by Latin hypercube and replicated Latin hypercube sampling algorithms. Finally, the investigations show that the most influential scanning parameter is the distance from the laser scanner to the object. The angle of incidence shows a significant effect for distances of 50 m and longer, while the surface quality contributes only negligible effects. The sampling width has no influence. Optimal scanning parameters can be found in the smallest possible object distance at an angle of incidence close to 0° in the highest surface quality. The consideration of correlations improves the estimation accuracy and underlines the importance of complete stochastic models for TLS measurements.

  8. Astrometric observations of visual binaries using 26-inch refractor during 2007-2014 at Pulkovo

    NASA Astrophysics Data System (ADS)

    Izmailov, I. S.; Roshchina, E. A.

    2016-04-01

    We present the results of 15184 astrometric observations of 322 visual binaries carried out in 2007-2014 at Pulkovo observatory. In 2007, the 26-inch refractor ( F = 10413 mm, D = 65 cm) was equipped with the CCD camera FLI ProLine 09000 (FOV 12' × 12', 3056 × 3056 pixels, 0.238 arcsec pixel-1). Telescope automation and weather monitoring system installation allowed us to increase the number of observations significantly. Visual binary and multiple systems with an angular distance in the interval 1."1-78."6 with 7."3 on average were included in the observing program. The results were studied in detail for systematic errors using calibration star pairs. There was no detected dependence of errors on temperature, pressure, and hour angle. The dependence of the 26-inch refractor's scale on temperature was taken into account in calculations. The accuracy of measurement of a single CCD image is in the range of 0."0005 to 0."289, 0."021 on average along both coordinates. Mean errors in annual average values of angular distance and position angle are equal to 0."005 and 0.°04 respectively. The results are available here http://izmccd.puldb.ru/vds.htmand in the Strasbourg Astronomical Data Center (CDS). In the catalog, the separations and position angles per night of observation and annual average as well as errors for all the values and standard deviations of a single observation are presented. We present the results of comparison of 50 pairs of stars with known orbital solutions with ephemerides.

  9. Assessing conditions influencing the longitudinal distribution of exotic brown trout (Salmo trutta) in a mountain stream: a spatially-explicit modeling approach

    USGS Publications Warehouse

    Meredith, Christy S.; Budy, Phaedra; Hooten, Mevin B.; Oliveira Prates, Marcos

    2017-01-01

    Trout species often segregate along elevational gradients, yet the mechanisms driving this pattern are not fully understood. On the Logan River, Utah, USA, exotic brown trout (Salmo trutta) dominate at low elevations but are near-absent from high elevations with native Bonneville cutthroat trout (Onchorhynchus clarkii utah). We used a spatially-explicit Bayesian modeling approach to evaluate how abiotic conditions (describing mechanisms related to temperature and physical habitat) as well as propagule pressure explained the distribution of brown trout in this system. Many covariates strongly explained redd abundance based on model performance and coefficient strength, including average annual temperature, average summer temperature, gravel availability, distance from a concentrated stocking area, and anchor ice-impeded distance from a concentrated stocking area. In contrast, covariates that exhibited low performance in models and/or a weak relationship to redd abundance included reach-average water depth, stocking intensity to the reach, average winter temperature, and number of days with anchor ice. Even if climate change creates more suitable summer temperature conditions for brown trout at high elevations, our findings suggest their success may be limited by other conditions. The potential role of anchor ice in limiting movement upstream is compelling considering evidence suggesting anchor ice prevalence on the Logan River has decreased significantly over the last several decades, likely in response to climatic changes. Further experimental and field research is needed to explore the role of anchor ice, spawning gravel availability, and locations of historical stocking in structuring brown trout distributions on the Logan River and elsewhere.

  10. Three-dimensional adult male head and skull contours.

    PubMed

    Lee, Calvin; Loyd, Andre M; Nightingale, Roger; Myers, Barry S; Damon, Andrew; Bass, Cameron R

    2014-01-01

    Traumatic brain injury (TBI) is a major public health issue, affecting millions of people annually. Anthropomorphic test devices (ATDs) and finite element models (FEMs) provide a means of understanding factors leading to TBI, potentially reducing the occurrence. Thus, there is a need to ensure that these tools accurately model humans. For example, the Hybrid III was not based on 3-dimensional human head shape data. The objective of this study is to produce average head and skull contours for an average U.S. male that can be used for ATDs and FEMs. Computed tomography (CT) scans of adult male heads were obtained from a database provided by the University of Virginia Center for Applied Biomechanics. An orthographic viewer was used to extract head and skull contours from the CT scans. Landmarks were measured graphically using HyperMesh (Altair, HyperWorks). To determine the head occipital condyle (OC) centroid, surface meshes of the OCs were made and the centroid of the surfaces was calculated. The Hybrid III contour was obtained using a MicroScribe Digitizer (Solution Technologies, Inc., Oella, MD). Comparisons of the average male and ATD contours were performed using 2 methods: (1) the midsagittal and midcoronal ATD contours relative to the OC centroid were compared to the corresponding 1 SD range of the average male contours; (2) the ATD sagittal contour was translated relative to the average male sagittal contour to minimize the area between the 2 contours. Average male head and skull contours were created. Landmark measurements were made for the dorsum sellae, nasion skin, nasion bone, infraorbital foramen, and external auditory meatus, all relative to the OC centroid. The Hybrid III midsagittal contour was outside the 1 SD range for 15.2 percent of the average male head contour but only by a maximum distance of 1.5 mm, whereas the Hybrid III midcoronal head contour was outside the 1 SD range for 12.2 percent of the average male head contour by a maximum distance of 2 mm. Minimization of the area between the midsagittal contours resulted in only 2.3 mm of translation, corroborating the good correlation between the contours established by initial comparison. Three-dimensional average male head and skull contours were created and measurements of landmark locations were made. It was found that the 50th percentile male Hybrid III corresponds well to the average male head contour and validated its 3D shape. Average adult head and skull contours and landmark data are available for public research use at http://biomechanics.pratt.duke.edu/data .

  11. The Challenges of Online Courses for the Instructor

    ERIC Educational Resources Information Center

    Jacobs, Pearl

    2013-01-01

    Universities across the country are steadily increasing their use of online courses. Society's demand for lifelong learning will encourage the advancement of distance learning. Research tells us that today the average person changes careers every ten years. In addition, the U.S. Department of Labor estimates that about 10% of workers change jobs…

  12. Community Gardening Project: Meredith College Students Explore Sustainability, Organics

    ERIC Educational Resources Information Center

    Roubanis, Jody L.; Landis, William

    2007-01-01

    Consuming locally grown foods promotes sustainable development and individual wellness (Waters, 2006). In the United States, the average food product travels 2,000 miles before reaching the consumer (Schlosser, 2001). This distance between producer and consumer is one reason that today's youth lack an understanding of the origin of the food they…

  13. Academic Integrity in Web Based Distance Education

    ERIC Educational Resources Information Center

    Baron, Julie; Crooks, Steven M.

    2005-01-01

    This paper reviews the literature relative to academic dishonesty in WBDE settings assuming the average class size to be 30-50 students with the instructor filling the role of facilitator, concept expert, grader and mentor when necessary. It shows that some common stereotypes about academic integrity and WBDE are unsubstantiated. In addition, it…

  14. The skier: his characteristics and preferences

    Treesearch

    William A. Leuschner; Roscoe B. Herrington

    1971-01-01

    Skiers are young and becoming younger, with increasing proportions of unmarried and female skiers. Many are students and roughly half of the remainder earn their livings as professionals (doctor, lawyer, teacher). Skiers have higher-than average incomes. Most skiers never go away overnight to ski and seldom travel great distances. Forty percent of the skiers have skied...

  15. Io with Loki Plume on Bright Limb

    NASA Image and Video Library

    1996-06-03

    NASA's Voyager 1 image of Io showing active plume of Loki on limb. Heart-shaped feature southeast of Loki consists of fallout deposits from active plume Pele. The images that make up this mosaic were taken from an average distance of approximately 490,000 kilometers (340,000 miles). http://photojournal.jpl.nasa.gov/catalog/PIA00010

  16. 41 CFR 302-4.201 - How are my authorized en route travel days and per diem determined for relocation travel?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES PERMANENT CHANGE OF... driving distance shall be not less than an average of 300 miles per calendar day. An exception to the... handicapped; or for other reasons acceptable to the agency. ...

  17. New Cadets and Other College Freshmen: Class of 1985.

    DTIC Science & Technology

    1982-04-01

    secondary school and socioeconomic backgrounds, values, interests, and activity patterns, and are based on the American Council on Education’s yearly...Year Graduated from High School ................................ 6 9. Distance from Home to College .................................. 6 10. Parents...Activities During Past Year .................................... 14 II. SECONDARY SCHOOL PERFORMANCE 19. Average Grade in Secondary School

  18. A filament of energetic particles near the high-latitude dawn magnetopause

    NASA Technical Reports Server (NTRS)

    Lui, A. T. Y.; Williams, D. J.; Mcentire, R. W.; Christon, S. P.; Jacquey, C.; Angelopoulos, V.; Yamamoto, T.; Kokubun, S.; Frank, L. A.; Ackerson, K. L.

    1994-01-01

    The Geotail satelite detected a filament of tailward-streaming energetic particles spatially separated from the boundary layer of energetic particles at the high-latitude dawn magnetopause at a downstream distance of approximately 80 R(sub E) on October 27, 1992. During this event, the composition and charge states of energetic ions at energies above approximately 10 keV show significant intermix of ions from solar wind and ionospheric sources. Detailed analysis leads to the deduction that the filament was moving southward towards the neutral sheet at an average speed of approximately 80 km/s, implying an average duskward electric field of approximately 1 mV/m. Its north-south dimension was approximately 1 R(sub E) and it was associated with an earthward directed field-aligned current of approximately 5 mA/m. The filament was separated from the energetic particle boundary layer straddling the magnetopause by approximately 0.8 R(sub E) and was inferred to be detached from the boundary layer at downstream distance beyond approximately 70 R(sub E) in the distant tail.

  19. Do minority and poor neighborhoods have higher access to fast-food restaurants in the United States?

    PubMed Central

    James, Peter; Arcaya, Mariana C.; Parker, Devin M.; Tucker-Seeley, Reginald

    2016-01-01

    Background Disproportionate access to unhealthy foods in poor or minority neighborhoods may be a primary determinant of obesity disparities. We investigated whether fast-food access varies by Census block group (CBG) percent black and poverty. Methods We measured the average driving distance from each CBG population-weighted centroid to the five closest top ten fast-food chains and CBG percent black and percent below poverty Results Among 209,091 CBGs analyzed (95.1% of all US CBGs), CBG percent black was positively associated with fast-food access controlling for population density and percent poverty (average distance to fast food was 3.56 miles closer (95% CI: -3.64, -3.48) in CBGs with the highest versus lowest quartile of percentage of black residents). Poverty was not independently associated with fast-food access. The relationship between fast-food access and race was stronger in CBGs with higher levels of poverty (p for interaction <0.0001). Conclusions Predominantly black neighborhoods had higher access to fast-food while poverty was not an independent predictor of fast-food access. PMID:24945103

  20. Prediction of acoustic feature parameters using myoelectric signals.

    PubMed

    Lee, Ki-Seung

    2010-07-01

    It is well-known that a clear relationship exists between human voices and myoelectric signals (MESs) from the area of the speaker's mouth. In this study, we utilized this information to implement a speech synthesis scheme in which MES alone was used to predict the parameters characterizing the vocal-tract transfer function of specific speech signals. Several feature parameters derived from MES were investigated to find the optimal feature for maximization of the mutual information between the acoustic and the MES features. After the optimal feature was determined, an estimation rule for the acoustic parameters was proposed, based on a minimum mean square error (MMSE) criterion. In a preliminary study, 60 isolated words were used for both objective and subjective evaluations. The results showed that the average Euclidean distance between the original and predicted acoustic parameters was reduced by about 30% compared with the average Euclidean distance of the original parameters. The intelligibility of the synthesized speech signals using the predicted features was also evaluated. A word-level identification ratio of 65.5% and a syllable-level identification ratio of 73% were obtained through a listening test.

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