Sample records for average occurrence rate

  1. Occurrence rate of dipolarization fronts in the plasma sheet: Cluster observations

    NASA Astrophysics Data System (ADS)

    Xiao, Sudong; Zhang, Tielong; Wang, Guoqiang; Volwerk, Martin; Ge, Yasong; Schmid, Daniel; Nakamura, Rumi; Baumjohann, Wolfgang; Plaschke, Ferdinand

    2017-08-01

    We investigate the occurrence rate of dipolarization fronts (DFs) in the plasma sheet by taking full advantage of all four Cluster satellites (C1-4) from years 2001 to 2009. In total, we select 466 joint-observation DF events, in which 318, 282, 254, and 236 DFs are observed by C1, C2, C3, and C4, respectively. Our findings are as follows: (1) the maximum occurrence rate is ˜ 15.3 events per day at X ˜ 15 RE in the XY plane, and the average occurrence rate is ˜ 5.4 events per day over the whole observation period; (2) the occurrence rate on the dusk side of the plasma sheet is larger and decreases with increasing BXY/BLobe; (3) the occurrence rate within |Y| < 6 RE increases gradually from X ≈ -19 to -15 RE and then decreases from X ≈ -15 to -10 RE; (4) the occurrence rate when AE > 200 nT is much larger than that when AE < 200 nT, indicating that DFs preferentially occur during high geomagnetic activity. The magnetic pileup and earthward and duskward ion flows could contribute to the increases in the occurrence rate from X ≈ -19 to -15 RE. We suggest that both geomagnetic activity and multiple DFs contribute to the high occurrence rate of the DFs. In addition, the finite length of the DF in the dawn-dusk direction can affect the chance that a satellite observes the DF.

  2. Precipitation and the occurrence of lyme disease in the Northeastern United States

    USGS Publications Warehouse

    McCabe, G.J.; Bunnell, J.E.

    2004-01-01

    The occurrence of Lyme disease is a growing concern in the United States, and various studies have been performed to understand the factors related to Lyme disease occurrence. In the United States, Lyme disease has occurred most frequently in the northeastern United States. Positive correlations between the number of cases of Lyme disease reported in the northeastern United States during the 1992-2002 period indicate that late spring/early summer precipitation was a significant climate factor affecting the occurrence of Lyme disease. When late spring/early summer precipitation was greater than average, the occurrence of Lyme disease was above average, possibly due to increased tick activity and survival rate during wet conditions. Temperature did not seem to explain the variability in Lyme disease reports for the northeastern United States. ?? Mary Ann Liebert, Inc.

  3. An Estimate of North Atlantic Basin Tropical Cyclone Activity for 2008

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.

    2008-01-01

    The statistics of North Atlantic basin tropical cyclones for the interval 1945-2007 are examined and estimates are given for the frequencies of occurrence of the number of tropical cyclones, number of hurricanes, number of major hurricanes, number of category 4/5 hurricanes, and number of U.S. land-falling hurricanes for the 2008 hurricane season. Also examined are the variations of peak wind speed, average peak wind speed per storm, lowest pressure, average lowest pressure per storm, recurrence rate and duration of extreme events (El Nino and La Nina), the variation of 10-yr moving averages of parametric first differences, and the association of decadal averages of frequencies of occurrence of North Atlantic basin tropical cyclones against decadal averages of Armagh Observatory, Northern Ireland, annual mean temperature (found to be extremely important for number of tropical cyclones and number of hurricanes). Because the 2008 hurricane season seems destined to be one that is non-El Nino-related and is a post-1995 season, estimates of the frequencies of occurrence for the various subsets of storms should be above long-term averages.

  4. [Analysis of the characteristics of toxins in 6005 cases of acute poisoning in Guangxi].

    PubMed

    Jiang, Dong-fang; Zhang, Zhen-ming; Hu, De-hong; Liu, Qing-hua

    2013-07-01

    To investigate the toxin characteristics of toxins in patients of acute poisoning in the Guangxi area. A retrospective study was conducted. The data of acute poisoning cases and the causative toxins collected from 63 hospitals of Guangxi, including 36 city hospitals, 12 county hospitals, and 15 township health centers from January 2005 to December 2009 were collected. The data were descriptively analyzed and classified by year. A total of 6005 cases with acute poisoning induced by 532 kinds of poisons were enrolled. The 532 kinds of toxin were classified by high-occurrence (producing poisoning for 5 continuous years), low-occurrence (leading to poisoning for 2-4 continuous years) and newly occurred categories (leading to poisoning only in 1 year). The numbers of poisons of these 3 categories accounted for 10.15% (54 kinds), 29.70% (158 kinds), 60.15% (320 kinds) of total number of poisons, respectively. There were 4688 (78.07%), 780 (12.99%), and 537 (8.94%) cases for each category respectively. And the poisoning cases of each toxin involved from 8 to 837, 2 to 25, and 1 to 69 cases respectively. 77.78% (42/54) of high-occurrence poisons affect more than 20 cases, and 89.87% (142/158), 98.75% (316/320) of low-occurrence and new-occurrence poisons involved less than 10 cases. In the dynamic analyses for 5 years, frequency of toxin caused by high-occurrence, low-occurrence and newly occurred poisons in 5 years were 5 times, 2.6 times, and 1 time, respectively. The number of poisons caused by the high-occurrence toxin each year were same, but the average-annual growth rates of poison numbers caused by the low-occurrence and new-occurrence poisons each year were 17.61% and 20.10%. The average-annual growth rates of poisoning cases caused by the 3 categories of poisons were 14.08%, 16.53%, 31.96%, and the average-annual growth rates of poisoning cases caused by each categories were 10.28%, 1.13%, 11.45%, respectively. In the high-occurrence category, the poison species was least, the poisoning cases were most, the variety of the affected cases by each poison was largest, and the case involved by each toxin was increased by year. But in the newly occurred category, the poison constituent ratio was largest, but the poisoning population was the least, the disparity of each poison was least, and the toxin increased and the population affected each year were elevated. The characteristics of low-occurrence poison were between high-occurrence poison and newly occurred poison.

  5. The solar cycle variation of coronal mass ejections and the solar wind mass flux

    NASA Technical Reports Server (NTRS)

    Webb, David F.; Howard, Russell A.

    1994-01-01

    Coronal mass ejections (CMEs) are an important aspect of coronal physics and a potentially significant contributor to perturbations of the solar wind, such as its mass flux. Sufficient data on CMEs are now available to permit study of their longer-term occurrency patterns. Here we present the results of a study of CME occurrence rates over more than a complete 11-year solar sunspot cycle and a comparison of these rates with those of other activity related to CMEs and with the solar wind particle flux at 1 AU. The study includes an evaluation of correlations to the CME rates, which include instrument duty cycles, visibility functions, mass detection thresholds, and geometrical considerations. The main results are as follows: (1) The frequency of occurrence of CMEs tends to track the solar activity cycle in both amplitude and phase; (2) the CME rates from different instruments, when corrected for both duty cycles and visibility functions, are reasonably consistent; (3) considering only longer-term averages, no one class of solar activity is better correlated with CME rate than any other; (4) the ratio of the annualized CME to solar wind mass flux tends to track the solar cycle; and (5) near solar maximum, CMEs can provide a significant fraction (i.e., approximately equals 15%) of the average mass flux to the near-ecliptic solar wind.

  6. Intense methane ebullition from open water area of a shallow peatland lake on the eastern Tibetan Plateau.

    PubMed

    Zhu, Dan; Wu, Yan; Chen, Huai; He, Yixin; Wu, Ning

    2016-01-15

    Methane fluxes from a shallow peatland lake (3450 m a.s.l., 1.6 km(2) in area, maximum depth <1m) on eastern Tibetan Plateau were measured with floating chamber method during May to August, 2009. The overall average of methane emission rate during the study period was 34.71±29.15 mg CH4 m(-2) h(-1). The occurrence of ebullition among the overall methane flux from Lake Medo was about 74%. The average rate of ebullition was 32.45±28.31 mg CH4 m(-2) h(-1), which accounted for 93% of the overall average of methane emission. Significant seasonal variation was found for occurrence (P<0.05) and rate (P<0.01) of ebullition, both peaking synchronously in mid-summer. Both the occurrence and rate of ebullition were found positively related to sediment temperature but negatively related to lake water depth. The high methane production in the lake sediment was likely fueled by organic carbon loaded from surrounding peatlands to the lake. The shallowness of the water column could be another important favorable factor for methane-containing bubble formation in the sediment and their transportation to the atmosphere. The methane ebullition must have been enhanced by the low atmospheric pressure (ca. 672 hPa) in the high-altitude environment. For a better understanding on the mechanism of methane emission from alpine lakes, more lakes on the Tibetan Plateau should be studied in the future for their methane ebullition. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Global distribution of neutral wind shear associated with sporadic E layers derived from GAIA

    NASA Astrophysics Data System (ADS)

    Shinagawa, H.; Miyoshi, Y.; Jin, H.; Fujiwara, H.

    2017-04-01

    There have been a number of papers reporting that the statistical occurrence rate of the sporadic E (Es) layer depends not only on the local time and season but also on the geographical location, implying that geographical and seasonal dependence in vertical neutral wind shear is one of the factors responsible for the geographical and seasonal dependence in Es layer occurrences rate. To study the role of neutral wind shear in the global distribution of the Es layer occurrence rate, we employ a self-consistent atmosphere-ionosphere coupled model called GAIA (Ground-to-topside model of Atmosphere and Ionosphere for Aeronomy), which incorporates meteorological reanalysis data in the lower atmosphere. The average distribution of neutral wind shear in the lower thermosphere is derived for the June-August and December-February periods, and the global distribution of vertical ion convergence is obtained to estimate the Es layer occurrence rate. It is found that the local and seasonal dependence of neutral wind shear is an important factor in determining the dependence of the Es layer occurrence rate on geographical distribution and seasonal variation. However, there are uncertainties in the simulated vertical neutral wind shears, which have larger scales than the observed wind shear scales. Furthermore, other processes such as localization of magnetic field distribution, background metallic ion distribution, ionospheric electric fields, and chemical processes of metallic ions are also likely to make an important contribution to geographical distribution and seasonal variation of the Es occurrence rate.

  8. The relationship between seizures, interictal spikes and antiepileptic drugs.

    PubMed

    Goncharova, Irina I; Alkawadri, Rafeed; Gaspard, Nicolas; Duckrow, Robert B; Spencer, Dennis D; Hirsch, Lawrence J; Spencer, Susan S; Zaveri, Hitten P

    2016-09-01

    A considerable decrease in spike rate accompanies antiepileptic drug (AED) taper during intracranial EEG (icEEG) monitoring. Since spike rate during icEEG monitoring can be influenced by surgery to place intracranial electrodes, we studied spike rate during long-term scalp EEG monitoring to further test this observation. We analyzed spike rate, seizure occurrence and AED taper in 130 consecutive patients over an average of 8.9days (range 5-17days). We observed a significant relationship between time to the first seizure, spike rate, AED taper and seizure occurrence (F (3,126)=19.77, p<0.0001). A high spike rate was related to a longer time to the first seizure. Further, in a subset of 79 patients who experienced seizures on or after day 4 of monitoring, spike rate decreased initially from an on- to off-AEDs epoch (from 505.0 to 382.3 spikes per hour, p<0.00001), and increased thereafter with the occurrence of seizures. There is an interplay between seizures, spikes and AEDs such that spike rate decreases with AED taper and increases after seizure occurrence. The direct relationship between spike rate and AEDs and between spike rate and time to the first seizure suggests that spikes are a marker of inhibition rather than excitation. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  9. An Examination of Sunspot Number Rates of Growth and Decay in Relation to the Sunspot Cycle

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.; Hathaway, David H.

    2006-01-01

    On the basis of annual sunspot number averages, sunspot number rates of growth and decay are examined relative to both minimum and maximum amplitudes and the time of their occurrences using cycles 12 through present, the most reliably determined sunspot cycles. Indeed, strong correlations are found for predicting the minimum and maximum amplitudes and the time of their occurrences years in advance. As applied to predicting sunspot minimum for cycle 24, the next cycle, its minimum appears likely to occur in 2006, especially if it is a robust cycle similar in nature to cycles 17-23.

  10. An Investigation of Tic Suppression and the Rebound Effect in Tourette's Disorder

    ERIC Educational Resources Information Center

    Meidinger, Amy L.; Miltenberger, Raymond G.; Himle, Michael; Omvig, Matthew; Trainor, Casey; Crosby, Ross

    2005-01-01

    Many patients, parents of children with Tourettes disorder, and professionals have suggested that following a period of suppression, tics will rebound to a rate that will exceed the average rate of occurrence. At present, there are no empirical data to support or refute such an effect. This experiment utilized an A-B-A design with replication to…

  11. 76 FR 40222 - Airworthiness Directives; Turbomeca S.A. ARRIEL 2B and 2B1 Turboshaft Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... sufficient to reduce the stress margin of the blade to a level consistent with the rate of occurrences of... stress. Comments We gave the public the opportunity to participate in developing this AD. We received no... would take about 60 work-hours per product to comply with this AD. The average labor rate is $85 per...

  12. Cause of different local time distribution in the postsunset equatorial ionospheric irregularity occurrences between June and December solstices

    NASA Astrophysics Data System (ADS)

    Su, S.-Y.; Chao, C. K.; Liu, C. H.

    2009-04-01

    Global averaged postsunset equatorial ionospheric density irregularity occurrences observed by ROCSAT during the moderate to high solar activity years of 1999 to 2004 indicate a different local time distribution between June and December solstices. The irregularity occurrences during the December solstice show a faster increase rate to peak at 2100-2200 local time, while the irregularity occurrences during the June solstice have a slower increase rate and peak one hour later in local time than that in the December solstice. The cause of such different local time distributions is attributed to a large contrast in the time of zonal drift reversal and the magnitude of postsunset vertical drift observed by ROCSAT at longitudes of large magnetic declination in the two solstices. That is, a delay in the zonal drift reversal in association with a smaller postsunset vertical drift observed at longitudes of positive magnetic declination has greatly inhibited the irregularity occurrences during the June solstice in contrast to an earlier zonal drift reversal together with a large vertical drift occurring at longitudes of negative magnetic declination to accelerate the irregularity occurrences during the December solstice. We think that the different geomagnetic field strengths that existed between the longitudes of positive and negative magnetic declinations have played a crucial role in determining the different local time distributions of irregularity occurrences for the two solstices.

  13. Statistical short-term earthquake prediction.

    PubMed

    Kagan, Y Y; Knopoff, L

    1987-06-19

    A statistical procedure, derived from a theoretical model of fracture growth, is used to identify a foreshock sequence while it is in progress. As a predictor, the procedure reduces the average uncertainty in the rate of occurrence for a future strong earthquake by a factor of more than 1000 when compared with the Poisson rate of occurrence. About one-third of all main shocks with local magnitude greater than or equal to 4.0 in central California can be predicted in this way, starting from a 7-year database that has a lower magnitude cut off of 1.5. The time scale of such predictions is of the order of a few hours to a few days for foreshocks in the magnitude range from 2.0 to 5.0.

  14. Time series models on analysing mortality rates and acute childhood lymphoid leukaemia.

    PubMed

    Kis, Maria

    2005-01-01

    In this paper we demonstrate applying time series models on medical research. The Hungarian mortality rates were analysed by autoregressive integrated moving average models and seasonal time series models examined the data of acute childhood lymphoid leukaemia.The mortality data may be analysed by time series methods such as autoregressive integrated moving average (ARIMA) modelling. This method is demonstrated by two examples: analysis of the mortality rates of ischemic heart diseases and analysis of the mortality rates of cancer of digestive system. Mathematical expressions are given for the results of analysis. The relationships between time series of mortality rates were studied with ARIMA models. Calculations of confidence intervals for autoregressive parameters by tree methods: standard normal distribution as estimation and estimation of the White's theory and the continuous time case estimation. Analysing the confidence intervals of the first order autoregressive parameters we may conclude that the confidence intervals were much smaller than other estimations by applying the continuous time estimation model.We present a new approach to analysing the occurrence of acute childhood lymphoid leukaemia. We decompose time series into components. The periodicity of acute childhood lymphoid leukaemia in Hungary was examined using seasonal decomposition time series method. The cyclic trend of the dates of diagnosis revealed that a higher percent of the peaks fell within the winter months than in the other seasons. This proves the seasonal occurrence of the childhood leukaemia in Hungary.

  15. Air and wet bulb temperature lapse rates and their impact on snowmaking in a Pyrenean ski resort

    NASA Astrophysics Data System (ADS)

    López-Moreno, Juan Ignacio; Navarro-Serrano, F.; Azorín-Molina, C.; Sánchez-Navarrete, P.; Alonso-González, E.; Rico, I.; Morán-Tejeda, E.; Buisan, S.; Revuelto, J.; Pons, M.; Vicente-Serrano, S. M.

    2018-03-01

    A set of 17 air temperature and relative humidity sensors were used to analyze the temporal variability of surface air temperature (Tair), wet bulb temperature (Twb), and daily snowmaking hours (SM, number of hours per day with Twb < - 2 °C), lapse rates, and the occurrence of thermal inversions at the Formigal ski resort (Spanish Pyrenees) from December to March during three consecutive ski seasons (2012-2013, 2013-2014, and 2014-2015). The Tair and Twb lapse rates showed strong hourly and daily variability, with both exhibiting almost identical temporal fluctuations. The Twb exhibited average lapse rates that were slightly steeper (- 5.2 °C/km) than those observed for Tair (- 4.9 °C/km). The less steep lapse rates and most thermal inversions were observed in December. Days having less (more) steep Tair and Twb lapse rates were observed under low (high) wind speeds and high (low) relative humidity and air pressure. The temporal dynamics of the SM lapse rates was more complex, as this involved consideration of the average Tair in the ski resort, in addition to the driving factors of the spatio-temporal variability of Twb. Thus, on a number of cold (warm) days, snowmaking was feasible at all elevations at the ski resort, independently of the slopes of the lapse rates. The SM exhibited an average daily lapse rate of 8.2 h/km, with a progressive trend of increase from December to March. Weather types over the Iberian Peninsula tightly control the driving factors of the Tair, Twb, and SM lapse rates (wind speed, relative humidity, and Tair), so the slopes of the lapse rates and the frequency of inversions in relation to elevation for the three variables are very dependent on the occurrence of specific weather types. The less steep lapse rates occurred associated with advections from the southeast, although low lapse rates also occurred during advections from the east and south, and under anticyclonic conditions. The steepest Tair and Twb lapse rates were observed during north and northwest advections, while the steepest rates for SM were observed during days of cyclonic circulation and advections from the northeast.

  16. A Statistical Study on VLF Subionospheric Perturbations Associated with Major Earthquakes: A View from Focal Mechanism

    NASA Astrophysics Data System (ADS)

    Kawano, T.; Tatsuta, K.; Hobara, Y.

    2015-12-01

    Continuous monitoring of signal amplitudes of worldwide VLF transmitters is a powerful tool to study the lower ionospheric condition. Although, lower ionospheric perturbations prior to some of the major earthquakes have been reported for years, their occurrence and coupling mechanism between the ground and overlaying ionosphere prior to the earthquakes are not clear yet. In this paper, we carried out a statistical analysis based on the nighttime averaged signal amplitude data from the UEC's VLF/LF transmitter observation network. Two hundred forty three earthquakes were occurred within the 5th Fresnel zone of transmitter-receiver paths around Japan during the time period of 2007 to 2012. These earthquakes were characterized into three different groups based on the Centroid-Moment-Tensor (CMT) solution such as reverse fault type, normal fault type and stress slip type. The ionospheric anomaly was identified by a large change in the VLF/LF amplitude during nighttime. As a result, we found the ionospheric perturbations associated with both ground and sea earthquakes. Remarkably, the reverse fault type earthquakes have the highest occurrence rate of ionospheric perturbation among the three types both for sea (41%) and ground events (61%). The occurrence rates for normal type fault are 35% and 56% for sea and ground earthquakes respectively and the same for stress slip type are 39% and 20% for sea and ground earthquakes respectively. In both cases the occurrence rates are smaller than the reverse fault type. The clear difference of occurrence rate of the ionospheric perturbations may indicate that the coupling efficiency of seismic activity into the overlaying ionosphere is controlled by the pressure in the earth's crust. This gives us further physical insight of Lithosphere-Atmosphere-Ionosphere (LAI) coupling processes.

  17. Cardiopulmonary events during primary colonoscopy screening in an average risk population.

    PubMed

    Khalid-de Bakker, C A; Jonkers, D M; Hameeteman, W; de Ridder, R J; Masclee, A A; Stockbrügger, R W

    2011-04-01

    Large colorectal cancer screening studies using primary colonoscopy have reported a low risk of major complications. Studies on diagnostic and therapeutic colonoscopy have pointed to a frequent occurrence of(minor) cardiopulmonary events, and with the steady increase of colonoscopy screening, it is important to investigate their occurrence in colonoscopy screening. This study describes the frequency of bradycardia(pulse rate <60 min-1), hypotension (systolic blood pressure(SB P) <90 mmHg), hypoxaemia (blood oxygenation, SaO2<90%) and ECG changes during colonoscopy screening in an average-risk population (hospital personnel, n=214,mean age 54.0±3.8, 39.3% male), without significant comorbidity) and aims at identifying subject-related and/or endoscopic factors associated with their occurrence. All data were collected prospectively. During 214 consecutive primary screening colonoscopies under conscious sedation(midazolam and pethidine), on top of pulse rate and SaO2,blood pressure and a three-channel ECG were recorded every five minutes. No major complications or relevant ECG changes occurred. Hypoxaemia occurred in 119 (55.6%),hypotension in 19 (8.9%) and bradycardia in 12 subjects(5.6%). In multivariate analysis, the sedation level 3 increased the risk of hypoxaemia (OR 4.8, CI 1.7-13.7), and incomplete colonoscopy (OR 5.3, CI 1.6-18.1) was associated with hypotension. Subjects with bradycardia had a longer mean procedure time (38±12 vs. 29±12 min, p<0.05), which did not turn out as a risk factor in a multivariate analysis. Mainly procedure-related and not subject-related factors were found to be associated with the occurrence of cardiopulmonary events in primary colonoscopy screening in this relatively healthy screening population.

  18. [Role of placental apoptosis in fetal growth restriction].

    PubMed

    Liu, Yuan; Gao, Peng; Xie, Yingbo; Wang, Shuyun; Dai, Minsheng; Jiang, Sen

    2002-12-01

    To determine the relationship of placental cellular apoptosis and pathophysiology of fetal growth restriction (FGR). Placental samples were obtained from 18 pregnancies complicated by FGR and 14 normal pregnancies. Terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) and transmission electron microscopy were used to confirm the occurrence of apoptosis. In FGR group the placental apoptosis rate was (n = 18) 12.1 per thousand, the average placental weight was (236 +/- 24) g, the average birth weight was (2,071 +/- 428) g; In normal group (n = 14), the placental apoptosis rate was 7.3 per thousand, the average placental weight was (354 +/- 63) g, the average birth weight was (3,411 +/- 588) g (P < 0.05). The incidence of apoptosis was significantly higher in placental samples from pregnancies with FGR compared with normal placental samples (P < 0.05). Under transmission election microscopy, apoptosis was obviously compact and the chromatins were formed as mass. These results suggest that apoptosis may play a role in the pathophysiologic mechanisms of FGR.

  19. Psychometric Analysis of the Revised Memory and Behavior Problems Checklist: Factor Structure of Occurrence and Reaction Ratings

    PubMed Central

    Roth, David L.; Gitlin, Laura N.; Coon, David W.; Stevens, Alan B.; Burgio, Louis D.; Gallagher-Thompson, Dolores; Belle, Steven H.; Burns, Robert

    2008-01-01

    A modified version of the Revised Memory and Behavior Problems Checklist (RMBPC; L. Teri et al., 1992) was administered across 6 different sites to 1,229 family caregivers of community-dwelling adults with dementia. The total sample was divided randomly into 2 subsamples. Principal components analyses on occurrence responses and reaction ratings from the first subsample resulted in a 3-factor solution that closely resembled the originally proposed dimensions (memory-related problems, disruptive behaviors, and depression). Confirmatory factor analyses on data from the second subsample indicated adequate fit for the 3-factor model. Correlations with other caregiver and care-recipient measures supported the convergent and discriminant validity of the RMBPC measures. In addition, female caregivers and White caregivers reported more problems, on average, than male caregivers and African American caregivers, respectively. PMID:14692875

  20. 1954 midsummer fuel moistures in Oregon and Washington national forests compared with other years.

    Treesearch

    Owen P. Cramer

    1955-01-01

    For the third successive year mid-fire-season fuel moistures on national forests of Oregon and Washington averaged higher than in the preceding year, and forest flammability was correspondingly lower. Generally high fuel-moisture conditions during 1954 are reflected in fire occurrence, which approached an all-time low. Fuel-moisture ratings are based on the 25 lowest...

  1. Effects of Temperature and Strain Rate on Tensile Deformation Behavior of 9Cr-0.5Mo-1.8W-VNb Ferritic Heat-Resistant Steel

    NASA Astrophysics Data System (ADS)

    Guo, Xiaofeng; Weng, Xiaoxiang; Jiang, Yong; Gong, Jianming

    2017-09-01

    A series of uniaxial tensile tests were carried out at different strain rate and different temperatures to investigate the effects of temperature and strain rate on tensile deformation behavior of P92 steel. In the temperature range of 30-700 °C, the variations of flow stress, average work-hardening rate, tensile strength and ductility with temperature all show three temperature regimes. At intermediate temperature, the material exhibited the serrated flow behavior, the peak in flow stress, the maximum in average work-hardening rate, and the abnormal variations in tensile strength and ductility indicates the occurrence of DSA, whereas the sharp decrease in flow stress, average work-hardening rate as well as strength values, and the remarkable increase in ductility values with increasing temperature from 450 to 700 °C imply that dynamic recovery plays a dominant role in this regime. Additionally, for the temperature ranging from 550 to 650 °C, a significant decrease in flow stress values is observed with decreasing in strain rate. This phenomenon suggests the strain rate has a strong influence on flow stress. Based on the experimental results above, an Arrhenius-type constitutive equation is proposed to predict the flow stress.

  2. Beat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node Cells

    PubMed Central

    Monfredi, Oliver; Maltseva, Larissa A.; Spurgeon, Harold A.; Boyett, Mark R.; Lakatta, Edward G.; Maltsev, Victor A.

    2013-01-01

    Spontaneous, submembrane local Ca2+ releases (LCRs) generated by the sarcoplasmic reticulum in sinoatrial nodal cells, the cells of the primary cardiac pacemaker, activate inward Na+/Ca2+-exchange current to accelerate the diastolic depolarization rate, and therefore to impact on cycle length. Since LCRs are generated by Ca2+ release channel (i.e. ryanodine receptor) openings, they exhibit a degree of stochastic behavior, manifested as notable cycle-to-cycle variations in the time of their occurrence. Aim The present study tested whether variation in LCR periodicity contributes to intrinsic (beat-to-beat) cycle length variability in single sinoatrial nodal cells. Methods We imaged single rabbit sinoatrial nodal cells using a 2D-camera to capture LCRs over the entire cell, and, in selected cells, simultaneously measured action potentials by perforated patch clamp. Results LCRs begin to occur on the descending part of the action potential-induced whole-cell Ca2+ transient, at about the time of the maximum diastolic potential. Shortly after the maximum diastolic potential (mean 54±7.7 ms, n = 14), the ensemble of waxing LCR activity converts the decay of the global Ca2+ transient into a rise, resulting in a late, whole-cell diastolic Ca2+ elevation, accompanied by a notable acceleration in diastolic depolarization rate. On average, cells (n = 9) generate 13.2±3.7 LCRs per cycle (mean±SEM), varying in size (7.1±4.2 µm) and duration (44.2±27.1 ms), with both size and duration being greater for later-occurring LCRs. While the timing of each LCR occurrence also varies, the LCR period (i.e. the time from the preceding Ca2+ transient peak to an LCR’s subsequent occurrence) averaged for all LCRs in a given cycle closely predicts the time of occurrence of the next action potential, i.e. the cycle length. Conclusion Intrinsic cycle length variability in single sinoatrial nodal cells is linked to beat-to-beat variations in the average period of individual LCRs each cycle. PMID:23826247

  3. Accounting for occurrences: a new view of the use of contingency information in causal judgment.

    PubMed

    White, Peter A

    2008-01-01

    When people make causal judgments from contingency information, a principal aim is to account for occurrences of the outcome. When 2 causes are under consideration, the capacity of either to account for occurrences is judged from how likely the cause is to be present when the outcome occurs and from the rate at which the outcome occurs when that cause alone is present, which gives an estimate of the strength of the cause. These propositions are formalized in a weighted averaging model, which successfully predicted several judgmental phenomena not predicted by other models of causal judgment. These include a tendency for judgment of one cause (A) to be reduced as the number of occurrences of when only the other one (B) increases and a tendency for A to receive higher judgments than B if A is better able to account for occurrences than B is even if B has a higher contingency with the outcome than A does. Overshadowing, a tendency for judgments of B to be depressed if A has a higher contingency, is weak or absent when B is better able to account for occurrences than A. Results of several experiments support these and related predictions derived from the accounting for occurrences hypothesis. PsycINFO Database Record (c) 2008 APA, all rights reserved.

  4. Variations of radon concentration in the atmosphere. Gamma dose rate

    NASA Astrophysics Data System (ADS)

    Tchorz-Trzeciakiewicz, D. E.; Solecki, A. T.

    2018-02-01

    The purposes of research were following: observation and interpretation of variations of radon concentration in the atmosphere - vertical, seasonal, spatial and analysis of relation between average annual radon concentration and ground natural radiation and gamma dose rate. Moreover we wanted to check the occurrence of radon density currents and the possibility of radon accumulation at the foot of the spoil tip. The surveys were carried out in Okrzeszyn (SW Poland) in the area of the spoil tip formed during uranium mining that took place in 60's of 20th century. The measurements were carried out in 20 measurements points at three heights: 0.2 m, 1 m and 2 m a.g.l. using SSNTD LR-115. The survey lasted one year and detectors were exchanged at the beginning of every season. Uranium eU (ppm), thorium eTh (ppm) and potassium K (%) contents were measured using gamma ray spectrometer Exploranium RS-230, ambient gamma dose rate using radiometer RK-100. The average radon concentration on this area was 52.8 Bq m-3. The highest radon concentrations were noted during autumn and the lowest during winter. We observed vertical variations of radon concentration. Radon concentrations decreased with increase of height above ground level. The decrease of radon with increase of height a.g.l. had logarithmic character. Spatial variations of radon concentrations did not indicate the occurrence of radon density currents and accumulation of radon at the foot of the spoil tip. The analysis of relation between average radon concentrations and ground natural radiation (uranium and thorium content) or gamma dose rate revealed positive relation between those parameters. On the base of results mentioned above we suggested that gamma spectrometry measurements or even cheaper and simpler ambient gamma dose rate measurements can be a useful tool in determining radon prone areas. This should be confirmed by additional research.

  5. Climate change and occurrence of diarrheal diseases: evolving facts from Nepal.

    PubMed

    Bhandari, G P; Gurung, S; Dhimal, M; Bhusal, C L

    2012-09-01

    Climate change is becoming huge threat to health especially for those from developing countries. Diarrhea as one of the major diseases linked with changing climate. This study has been carried out to assess the relationship between climatic variables, and malaria and to find out the range of non-climatic factors that can confound the relationship of climate change and human health. It is a Retrospective study where data of past ten years relating to climate and disease (diarrhea) variable were analyzed. The study conducted trend analysis based on correlation. The climate related data were obtained from Department of Hydrology and Meteorology. Time Series analysis was also being conducted. The trend of number of yearly cases of diarrhea has been increasing from 1998 to 2001 after which the cases remain constant till 2006.The climate types in Jhapa vary from humid to per-humid based on the moisture index and Mega-thermal based on thermal efficiency. The mean annual temperature is increasing at an average of 0.04 °C/year with maximum temperature increasing faster than the minimum temperature. The annual total rainfall of Jhapa is decreasing at an average rate of -7.1 mm/year. Statistically significant correlation between diarrheal cases occurrence and temperature and rainfall has been observed. However, climate variables were not the significant predictors of diarrheal occurrence. The association among climate variables and diarrheal disease occurrence cannot be neglected which has been showed by this study. Further prospective longitudinal study adjusting influence of non-climatic factors is recommended.

  6. ERMiT: Estimating Post-Fire Erosion in Probabilistic Terms

    NASA Astrophysics Data System (ADS)

    Pierson, F. B.; Robichaud, P. R.; Elliot, W. J.; Hall, D. E.; Moffet, C. A.

    2006-12-01

    Mitigating the impact of post-wildfire runoff and erosion on life, property, and natural resources have cost the United States government tens of millions of dollars over the past decade. The decision of where, when, and how to apply the most effective mitigation treatments requires land managers to assess the risk of damaging runoff and erosion events occurring after a fire. The Erosion Risk Management Tool (ERMiT) is a web-based application that estimates erosion in probabilistic terms on burned and recovering forest, range, and chaparral lands. Unlike most erosion prediction models, ERMiT does not provide `average annual erosion rates;' rather, it provides a distribution of erosion rates with the likelihood of their occurrence. ERMiT combines rain event variability with spatial and temporal variabilities of hillslope burn severity, soil properties, and ground cover to estimate Water Erosion Prediction Project (WEPP) model input parameter values. Based on 20 to 40 individual WEPP runs, ERMiT produces a distribution of rain event erosion rates with a probability of occurrence for each of five post-fire years. Over the 5 years of modeled recovery, the occurrence probability of the less erodible soil parameters is increased and the occurrence probability of the more erodible soil parameters is decreased. In addition, the occurrence probabilities and the four spatial arrangements of burn severity (arrangements of overland flow elements (OFE's)), are shifted toward lower burn severity with each year of recovery. These yearly adjustments are based on field measurements made through post-fire recovery periods. ERMiT also provides rain event erosion rate distributions for hillslopes that have been treated with seeding, straw mulch, straw wattles and contour-felled log erosion barriers. Such output can help managers make erosion mitigation treatment decisions based on the probability of high sediment yields occurring, the value of resources at risk for damage, cost, and other management considerations.

  7. Foreshock occurrence rates before large earthquakes worldwide

    USGS Publications Warehouse

    Reasenberg, P.A.

    1999-01-01

    Global rates of foreshock occurrence involving shallow M ??? 6 and M ??? 7 mainshocks and M ??? 5 foreshocks were measured, using earthquakes listed in the Harvard CMT catalog for the period 1978-1996. These rates are similar to rates ones measured in previous worldwide and regional studies when they are normalized for the ranges of magnitude difference they each span. The observed worldwide rates were compared to a generic model of earthquake clustering, which is based on patterns of small and moderate aftershocks in California, and were found to exceed the California model by a factor of approximately 2. Significant differences in foreshock rate were found among subsets of earthquakes defined by their focal mechanism and tectonic region, with the rate before thrust events higher and the rate before strike-slip events lower than the worldwide average. Among the thrust events a large majority, composed of events located in shallow subduction zones, registered a high foreshock rate, while a minority, located in continental thrust belts, measured a low rate. These differences may explain why previous surveys have revealed low foreshock rates among thrust events in California (especially southern California), while the worldwide observations suggest the opposite: California, lacking an active subduction zone in most of its territory, and including a region of mountain-building thrusts in the south, reflects the low rate apparently typical for continental thrusts, while the worldwide observations, dominated by shallow subduction zone events, are foreshock-rich.

  8. Effects of overcast and foggy conditions on transpiration rates of Pinus patula trees along a chronosequence within the cloud belt of the Sierra madre Oriental, central Veracrusz, Mexico

    USDA-ARS?s Scientific Manuscript database

    Pinus patula is a native tree species of the montane cloud belt of central Veracruz, Mexico, and one of the most popular species for regional reforestation efforts, both within and outside its natural range of occurrence. Projected regional climate change is likely to cause a rise in the average clo...

  9. Health Effects of Exposure to Natural Arsenic in Groundwater and Coal in China: An Overview of Occurrence

    PubMed Central

    Yu, Guangqian; Sun, Dianjun; Zheng, Yan

    2007-01-01

    Between 2001 and 2005, 21,155 of 445,638 wells in 20,517 villages in 292 counties in 16 provinces from China, or 5% of wells, were found to contain > 50 μg/L arsenic (As) by field testing with the Merck As kit. We achieved quality assurance of analysis of at least 10% of the wells containing > 50 μg/L As using hydride generation atomic fluorescence spectrometry and silver dithiodicarbomate spectrometry. Our best estimate of the population exposed to > 50 μg/L As in drinking water was 582,769. This is probably an underestimate for China because of the limited area surveyed. In a survey of 135,492 individuals in eight provinces, we used the National Diagnosis Standard for Endemic Arsenicosis and identified 10,096 cases of arsenicosis with various degrees of skin lesions. The arsenicosis occurrence rate of 7.5% is likely an overestimate, because the survey focused more on known and suspected endemic areas of arsenicosis. The occurrence of arsenicosis correlates positively with the percentage of wells containing > 50 μg/L As, or at a ratio of 1 to 5%. Based on both the amount of As in well water and the rate of occurrence of arsenicosis, Shanxi province, Inner Mongolia autonomous region, and Jilin province are the top three areas in China as of 2005 for exposure to endemic As from drinking water. Our survey also identified exposure to high levels of As from wells in several provinces and from the indoor burning of coal containing high levels of As in Shaanxi province. These areas, however, have not had any reports of previous arsenicosis endemics. In the endemic areas, the average rate of occurrence of arsenicosis at advanced stages was 1.2%, possibly because of a long exposure time of > 20 years; the rate of occurrence increased to 2.7% when we included a high dose of As exposure from the indoor burning of coal. Mitigation to reduce As exposure remains a challenge in rural China. PMID:17450236

  10. Quality of Pinzgau bull spermatozoa following different periods of cryostorage.

    PubMed

    Chrenek, P; Spaleková, E; Olexikova, L; Makarevich, A; Kubovicova, E

    2017-04-01

    The aim of this work was to examine the influence of cryostorage duration of Pinzgau bull's insemination doses (IDs) on some sperm traits. The IDs were frozen by a slow freezing method and stored in liquid nitrogen for different periods: less than 8 years (group 1), 8-13 years (group 2) and 14-18 years (group 3). Motility (CASA), pathological sperm rate (Giemsa staining), apoptotic (Yo-Pro-1-positive) and necrotic (propidium iodide-positive) cell occurrence and fertilizing ability (penetration/fertilization test) of spermatozoa were evaluated post-thaw. The average post-thaw sperm motility in all examined groups was over 40%. No significant influence of storage length either on the sperm total motility or progressive movement was revealed. In each tested group the average rate of malformed spermatozoa did not exceed 20%. No effect of cryostorage length on the occurrence of apoptotic or necrotic sperm was noted. Similarly, penetrating/fertilizing ability of sperm did not differ among the groups, excepting differences in the rate of pronuclei (PN) formation. In group 1, 72.9% of eggs showed two visible PN following 20 h incubation with sperm, whilst in groups 2 and 3 only 67 and 54.5% of zygotes, respectively, had both PN at this time. These results revealed no influence of storage time on the bull spermatozoa in all parameters excepting the rate of PN formation. As high inter-male variability was observed in the susceptibility of bull sperm to cryostorage, individual differences should be taken into account when semen from individual bulls is to be stored for a long time.

  11. On the Impact Angle of Hurricane Sandy's New Jersey Landfall

    NASA Technical Reports Server (NTRS)

    Hall, Timothy M.; Sobel, Adam H.

    2013-01-01

    Hurricane Sandy's track crossed the New Jersey coastline at an angle closer to perpendicular than any previous hurricane in the historic record, one of the factors contributing to recordsetting peak-water levels in parts of New Jersey and New York. To estimate the occurrence rate of Sandy-like tracks, we use a stochastic model built on historical hurricane data from the entire North Atlantic to generate a large sample of synthetic hurricanes. From this synthetic set we calculate that under long-term average climate conditions, a hurricane of Sandy's intensity or greater (category 1+) makes NJ landfall at an angle at least as close to perpendicular as Sandy's at an average annual rate of 0.0014 yr-1 (95% confidence range 0.0007 to 0.0023); i.e., a return period of 714 years (95% confidence range 435 to 1429).

  12. Earthquake stress drops, ambient tectonic stresses and stresses that drive plate motions

    USGS Publications Warehouse

    Hanks, T.C.

    1977-01-01

    A variety of geophysical observations suggests that the upper portion of the lithosphere, herein referred to as the elastic plate, has long-term material properties and frictional strength significantly greater than the lower lithosphere. If the average frictional stress along the non-ridge margin of the elastic plate is of the order of a kilobar, as suggested by the many observations of the frictional strength of rocks at mid-crustal conditions of pressure and temperature, the only viable mechanism for driving the motion of the elastic plate is a basal shear stress of several tens of bars. Kilobars of tectonic stress are then an ambient, steady condition of the earth's crust and uppermost mantle. The approximate equality of the basal shear stress and the average crustal earthquake stress drop, the localization of strain release for major plate margin earthquakes, and the rough equivalence of plate margin slip rates and gross plate motion rates suggest that the stress drops of major plate margin earthquakes are controlled by the elastic release of the basal shear stress in the vicinity of the plate margin, despite the existence of kilobars of tectonic stress existing across vertical planes parallel to the plate margin. If the stress differences available to be released at the time of faulting are distributed in a random, white fasbion with a mean-square value determined by the average earthquake stress drop, the frequency of occurrence of constant stress drop earthquakes will be proportional to reciprocal faulting area, in accordance with empirically known frequency of occurrence statistics. ?? 1977 Birkha??user Verlag.

  13. Uncertainty in biological monitoring: a framework for data collection and analysis to account for multiple sources of sampling bias

    USGS Publications Warehouse

    Ruiz-Gutierrez, Viviana; Hooten, Melvin B.; Campbell Grant, Evan H.

    2016-01-01

    Biological monitoring programmes are increasingly relying upon large volumes of citizen-science data to improve the scope and spatial coverage of information, challenging the scientific community to develop design and model-based approaches to improve inference.Recent statistical models in ecology have been developed to accommodate false-negative errors, although current work points to false-positive errors as equally important sources of bias. This is of particular concern for the success of any monitoring programme given that rates as small as 3% could lead to the overestimation of the occurrence of rare events by as much as 50%, and even small false-positive rates can severely bias estimates of occurrence dynamics.We present an integrated, computationally efficient Bayesian hierarchical model to correct for false-positive and false-negative errors in detection/non-detection data. Our model combines independent, auxiliary data sources with field observations to improve the estimation of false-positive rates, when a subset of field observations cannot be validated a posteriori or assumed as perfect. We evaluated the performance of the model across a range of occurrence rates, false-positive and false-negative errors, and quantity of auxiliary data.The model performed well under all simulated scenarios, and we were able to identify critical auxiliary data characteristics which resulted in improved inference. We applied our false-positive model to a large-scale, citizen-science monitoring programme for anurans in the north-eastern United States, using auxiliary data from an experiment designed to estimate false-positive error rates. Not correcting for false-positive rates resulted in biased estimates of occupancy in 4 of the 10 anuran species we analysed, leading to an overestimation of the average number of occupied survey routes by as much as 70%.The framework we present for data collection and analysis is able to efficiently provide reliable inference for occurrence patterns using data from a citizen-science monitoring programme. However, our approach is applicable to data generated by any type of research and monitoring programme, independent of skill level or scale, when effort is placed on obtaining auxiliary information on false-positive rates.

  14. Hesitations in continuous tracking induced by a concurrent discrete task

    NASA Technical Reports Server (NTRS)

    Klapp, S. T.; Kelly, P. A.; Netick, A.

    1985-01-01

    Subjects performed a continuous visually-guided pursuit tracking task with the right hand. From time to time (intervals averaging 30 sec) an auditory tone appeared signaling the subjects to perform a discrete response with the left hand. The presence of this tone was frequently associated with a hesitation in right-hand tracking which lasted 1/3 sec or longer. The rate of occurrence of these hesitations was about the same when the left-hand response involved a choice between competing responses as when the left hand responded in a predetermined direction. Hesitations occurred for three different mechanical tracking manipulanda using different controlling muscles, and appeared to be due to freezing rather than to relaxation of muscular action. The rate of occurrence of hesitations declined with practice, and this improvement in right-hand performance was accompanied by an improvement in performance of the concurrent left-hand response. The presence of hesitations, and their reduction with practice, can be interpreted within several viewpoints.

  15. Insight into the Physical and Dynamical Processes that Control Rapid Increases in Total Flash Rate

    NASA Technical Reports Server (NTRS)

    Schultz, Christopher J.; Carey, Lawrence D.; Schultz, Elise V.; Blakeslee, Richard J.; Goodman, Steven J.

    2015-01-01

    Rapid increases in total lightning (also termed "lightning jumps") have been observed for many decades. Lightning jumps have been well correlated to severe and hazardous weather occurrence. The main focus of lightning jump work has been on the development of lightning algorithms to be used in real-time assessment of storm intensity. However, in these studies it is typically assumed that the updraft "increases" without direct measurements of the vertical motion, or specification of which updraft characteristic actually increases (e.g., average speed, maximum speed, or convective updraft volume). Therefore, an end-to-end physical and dynamical basis for coupling rapid increases in total flash rate to increases in updraft speed and volume must be understood in order to ultimately relate lightning occurrence to severe storm metrics. Herein, we use polarimetric, multi-Doppler, and lightning mapping array measurements to provide physical context as to why rapid increases in total lightning are closely tied to severe and hazardous weather.

  16. Influence of pulse repetition rate on percussion drilling of Ti-based alloy by picosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Kononenko, Taras V.; Freitag, Christian; Sovyk, Dmitry N.; Lukhter, Alexander B.; Skvortsov, Konstantin V.; Konov, Vitaly I.

    2018-04-01

    Percussion drilling of a Ti-based alloy with 8 ps laser pulses was investigated with emphasis on the influence of the pulse repetition rate (1-300 kHz) on the drilling process. Heat accumulation is found to be responsible for simultaneous significant rise of the average drilling rate, the occurrence of a rim around the hole entrance, as well as noticeable surface oxidation. This can be observed as soon as the repetition rate exceeds a certain critical value, which depends on the pulse energy applied. Dramatic rise of the recast layer thickness inside the growing hole was revealed for the limited range of the repetition rates around the lower boundary of the heat accumulation regime. Possible origins of this phenomenon are discussed.

  17. The location and rate of occurrence of near-Earth magnetotail reconnection as observed by Cluster and Geotail

    NASA Astrophysics Data System (ADS)

    Genestreti, K. J.; Fuselier, S. A.; Goldstein, J.; Nagai, T.; Eastwood, J. P.

    2014-12-01

    A statistical characterization of the location and rate of occurrence of magnetic reconnection in the near-Earth magnetotail is performed by analyzing the set of ion diffusion region (DR) observations made by the Cluster and Geotail spacecraft during solar maximum and the declining phase. The occurrence rate is analyzed in terms of its dependence on both XGSM* and YGSM* (where coordinates are in the solar wind aberrated geocentric solar magnetospheric system). Within the limits of the statistics available to this study, we find the purely XGSM* -dependent occurrence rate to be roughly constant over a large portion of the near-Earth magnetotail. In contrast, we find the purely YGSM* -dependent occurrence rate to be biased towards dusk with a local maximum between 0RE ≤YGSM* ≤ 5RE. The YGSM* -dependent occurrence rate is then used to construct a quasi-2D formulation of the DR occurrence rate, which has explicit dependence on XGSM* and implicit dependence on YGSM*. The quasi-2D occurrence rate is then used to examine the predicted ephemeris of the Magnetospheric MultiScale (MMS) spacecraft. We estimate that, during its near-Earth magnetotail survey phase, MMS will likely observe 11±4 DR events. • The occurrence rate of events is calculated as a function of XGSM and YGSM. • The occurrence rate is used to estimate the number of events MMS will observe.

  18. The epidemiology of homicidal strangulation in the City of Johannesburg, South Africa.

    PubMed

    Suffla, Shahnaaz; Seedat, Mohamed

    2016-01-01

    Studies that provide accurate descriptions of the occurrence of fatal strangulation events are limited, both in South Africa and elsewhere in the world. The current study describes the extent and distribution of female and male homicidal strangulation in the City of Johannesburg for the period 2001-2010. The study is a register-based cross sectional study of homicidal strangulation that draws on data recorded by the National Injury Mortality Surveillance System. Crude, unadjusted strangulation rates, and proportions of strangulation across specific circumstances of occurrence were computed for each year and aggregated in some instances. Results indicated fatal strangulation to be the fourth leading cause of homicide in the City of Johannesburg. A total of 334 strangulation homicides were recorded, representing an average annual strangulation homicide rate of 0.90 per 100,000 population. Gender disproportionality in victimisation was reflected in the average annual rate of 1.03 per 100,000 population for females and 0.74 per 100,000 population for males. The highest rates were recorded among the elderly, and amongst coloured females and white males. Temporal and spatial descriptions indicated that victims were strangled primarily during the day, over the weekday period, and in private locations. When the scene of death was considered by race and age group, results indicated the victimisation of white females and males in private places, and the elderly in private settings. The majority of strangulation victims tested negative for alcohol. The results highlight the need for multi-level prevention strategies that target specific risk groups and situations. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  19. Seizure prediction in hippocampal and neocortical epilepsy using a model-based approach

    PubMed Central

    Aarabi, Ardalan; He, Bin

    2014-01-01

    Objectives The aim of this study is to develop a model based seizure prediction method. Methods A neural mass model was used to simulate the macro-scale dynamics of intracranial EEG data. The model was composed of pyramidal cells, excitatory and inhibitory interneurons described through state equations. Twelve model’s parameters were estimated by fitting the model to the power spectral density of intracranial EEG signals and then integrated based on information obtained by investigating changes in the parameters prior to seizures. Twenty-one patients with medically intractable hippocampal and neocortical focal epilepsy were studied. Results Tuned to obtain maximum sensitivity, an average sensitivity of 87.07% and 92.6% with an average false prediction rate of 0.2 and 0.15/h were achieved using maximum seizure occurrence periods of 30 and 50 min and a minimum seizure prediction horizon of 10 s, respectively. Under maximum specificity conditions, the system sensitivity decreased to 82.9% and 90.05% and the false prediction rates were reduced to 0.16 and 0.12/h using maximum seizure occurrence periods of 30 and 50 min, respectively. Conclusions The spatio-temporal changes in the parameters demonstrated patient-specific preictal signatures that could be used for seizure prediction. Significance The present findings suggest that the model-based approach may aid prediction of seizures. PMID:24374087

  20. Arbuscular mycorrhizal fungi in the tree seedlings of two Australian rain forests: occurrence, colonization, and relationships with plant performance.

    PubMed

    Gehring, Catherine A; Connell, Joseph H

    2006-03-01

    The roots of rain forest plants are frequently colonized by arbuscular mycorrhizal fungi (AMF) that can promote plant growth in the nutrient poor soils characteristic of these forests. However, recent studies suggest that both the occurrence of AMF on rain forest plants and the dependence of rain forest plants on AMF can be highly variable. We examined the occurrence and levels of AMF colonization of some common seedling species in a tropical and a subtropical rain forest site in Queensland, Australia. We also used a long-term database to compare the growth and mortality rates of seedling species that rarely formed AMF with those that regularly formed AMF. In both forests, more than one-third of the seedling species rarely formed AMF associations, while 40% of species consistently formed AMF in the tropical site compared to 27% in the subtropical site. Consistent patterns of AMF occurrence were observed among plant families at the two sites. Variation among seedling species in AMF occurrence or colonization was not associated with differences in seed mass among species, variation in seedling size and putative age within a species, or lack of AMF inoculum in the soil. Comparisons of four seedling species growing both in the shaded understory and in small canopy gaps revealed an increase in AMF colonization in two of the four species in gaps, suggesting that light limitation partially explains the low occurrence of AMF. Seedling survival was significantly positively associated with seed biomass but not with AMF colonization. Furthermore, seedling species that regularly formed AMF and those that did not had similar rates of growth and survival, suggesting that mycorrhizal and nonmycorrhizal strategies were equivalent in these forests. Furthermore, the high numbers of seedlings that lacked AMF and the overall low rate of seedling growth (the average seedling required 6 years to double its height) suggest that most seedlings did not receive significant indirect benefits from AMF through connection to canopy trees via a common mycorrhizal network.

  1. Increasing molecular weight parameters of a helical polymer through polymerization in a chiral solvent.

    PubMed

    Holder, Simon J; Achilleos, Mariliz; Jones, Richard G

    2006-09-27

    In this communication, we will demonstrate that polymerization in a chiral solvent can affect the molecular weight distribution of the product by perturbing the balance of the P and M helical screw senses of the growing chains. Specifically, for the Wurtz-type synthesis of polymethylphenylsilane (PMPS) in either (R) or (S)-limonene, the weight-average molecular weight of the products (average Mw = 80 000) was twice that of PMPS synthesized in (R/S)-limonene (average Mw = 39 200). Peturbation of the helical segmentation along the polymer chains leads to a reduction in the rate of occurrence of a key termination step. This the first time that a chiral solvent has been demonstrated to have such an effect on a polymerization process in affecting molecular weight parameters in contrast to affecting tacticity.

  2. Residual Strahls in Solar Wind Electron Dropouts: Signatures of Magnetic Connection to the Sun, Disconnection, or Interchange Reconnection?

    NASA Technical Reports Server (NTRS)

    Crooker, N. U.; Pagel, C.

    2008-01-01

    A recent assessment of suprathermal electron heat flux dropouts (HFDs) in the solar wind eliminated 90% as possible signatures of field lines disconnected from the Sun at both ends (Pagel et al., 2005b). The primary reason for elimination was the presence of a residual field-aligned strahl presumably signaling field lines connected to the Sun. Using high-time-resolution data from the Wind spacecraft, this paper tests whether the residual strahls were an artifact of averaging over pitch angle distributions (PADs) with and without strahls. An automated search for PADs without strahls (flat PADs) yields an occurrence rate of only 14% within HFDs, but a detailed case study shows that these flat PADs are imbedded within intervals of nearly flat PADs, that is, PADS with residual strahls that cannot be artifacts of averaging. An attractive alternative is that the residual strahls result from intermixing of originally back-scattered fluxes (haloes) of unequal intensities on field lines that have either disconnected or interchange reconnected at the Sun. A reevaluation of reported streaming of higher-energy electrons in HFDs suggests a similar cause. While the high-time-resolution data show high variability of PAD profiles within HFDs, this paper reopens the possibility that a substantial fraction signal disconnection or interchange reconnection. Estimated occurrence rates of fields having undergone these processes based upon published HFD rates are of the same order of magnitude as the surprisingly low values of 1-5% recently predicted by a model of a balanced heliospheric flux budget (Owens and Crooker, 2007).

  3. Effect of Climatic Factors on Hand, Foot, and Mouth Disease in South Korea, 2010-2013.

    PubMed

    Kim, Bryan Inho; Ki, Hyunok; Park, Sunhee; Cho, Eunhi; Chun, Byung Chul

    2016-01-01

    Hand, foot, and mouth disease (HFMD) causes characteristic blisters and sores mainly in infants and children, and has been monitored in South Korea through sentinel surveillance since 2009. We described the patterns of HFMD occurrence and analyzed the effect of climatic factors on national HFMD incidence. Weekly clinically diagnosed HFMD case rates (per 1,000 outpatients) in sentinel sites and weekly climatic factors, such as average temperature, relative humidity, duration of sunshine, precipitation, and wind speed from 2010 to 2013, were used in this study. A generalized additive model with smoothing splines and climatic variables with time lags of up to 2 weeks were considered in the modeling process. To account for long-term trends and seasonality, we controlled for each year and their corresponding weeks. The autocorrelation issue was also adjusted by using autocorrelation variables. At an average temperature below 18°C, the HFMD rate increased by 10.3% for every 1°C rise in average temperature (95% confidence interval (CI): 8.4, 12.3%). We also saw a 6.6% increase in HFMD rate (95% CI: 3.6, 9.7%) with every 1% increase in relative humidity under 65%, with a 1.5% decrease in HFMD rate observed (95% CI: 0.4, 2.7%) with each 1% humidity increase above 65%. Modeling results have shown that average temperature and relative humidity are related to HFMD rate. Additional research on the environmental risk factors of HFMD transmission is required to understand the underlying mechanism between climatic factors and HFMD incidence.

  4. The Children, Intimate Relationships, and Conflictual Life Events (CIRCLE) interview for simultaneous measurement of intimate partner and parent to child aggression.

    PubMed

    Marshall, Amy D; Feinberg, Mark E; Jones, Damon E; Chote, Daniel R

    2017-08-01

    Despite substantial rates of parent to child aggression (PCA) and intimate partner aggression (IPA) co-occurrence within families, the co-occurrence of PCA and IPA within incidents of aggression has not previously been examined. To do so, we developed the Children, Intimate Relationships, and Conflictual Life Events (CIRCLE) interview to simultaneously measure incidents of psychological and physical PCA and IPA. The CIRCLE interview was administered quarterly for approximately 1 year to 109 women and 94 men from 111 couples with a first born child approximately 32 months of age at study initiation. Demonstrating the CIRCLE interview's ability to yield new knowledge about the nature of family aggression, we describe the frequency of aggressive incidents, the average number of aggressive behaviors within incidents, the daily occurrence of multiple aggressive incidents, and rates of within-incident PCA and IPA co-occurrence. With the exception of men's physical IPA, aggression scores derived from the CIRCLE interview exhibited a relatively high degree of interpartner reporting concordance, as well as structural validity and convergent validity with common aggression measures. Aggression reports via repeated testing were not influenced by social desirability or attempts to avoid aggression. Participants who perceived enhanced memory for aggression as a function of study participation reported increasing PCA and IPA frequencies over time. In the prediction of child conduct and emotional problems, the CIRCLE interview demonstrated predictive validity and incremental validity over traditional aggression measures. For the first time, within-incident co-occurrence of PCA and IPA was documented and shown to uniquely impact child outcomes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Rate of occurrence, gross appearance, and age relation of hyperostosis frontalis interna in females: a prospective autopsy study.

    PubMed

    Nikolić, Slobodan; Djonić, Danijela; Zivković, Vladimir; Babić, Dragan; Juković, Fehim; Djurić, Marija

    2010-09-01

    The aim of our study was to determine rate of occurrence and appearance of hyperostosis frontalis interna (HFI) in females and correlation of this phenomenon with ageing. The sample included 248 deceased females: 45 of them with different types of HFI, and 203 without HFI, average age 68.3 +/- 15.4 years (range, 19-93), and 58.2 +/- 20.2 years (range, 10-101), respectively. According to our results, the rate of HFI was 18.14%. The older the woman was, the higher the possibility of HFI occurring (Pearson correlation 0.211, N=248, P=0.001), but the type of HFI did not correlate with age (Pearson correlation 0.229, N=45, P=0.131). Frontal and temporal bone were significantly thicker in women with than in women without HFI (t= -10.490, DF=246, P=0.000, and t= -5.658, DF=246, P=0.000, respectively). These bones became thicker with ageing (Pearson correlation 0.178, N=248, P=0.005, and 0.303, N=248, P=0.000, respectively). The best predictors of HFI occurrence were respectively, frontal bone thickness, temporal bone thickness, and age(Wald. coeff.=35.487, P=0.000; Wald. coeff.=3.288, P=0.070, and Wald.coeff. =2.727, P =0.099). Diagnosis of HFI depends not only on frontal bone thickness, but also on waviness of internal plate of the frontal bone, as well as-the involvement of the inner bone surface.

  6. Rainfall-induced slope failures near Los Angeles detected by time series of high-resolution satellite imagery

    NASA Astrophysics Data System (ADS)

    McKinney, E.; Moon, S.

    2017-12-01

    Tectonically active, soil mantled, and often fire-scorched landscapes of the Los Angeles region are susceptible to slope failures, such as mudflow and landslides, during high-intensity precipitation events. During 2016-2017, this area received a precipitation rate that was 90 mm higher than the long-term precipitation rates averaged over 30 years. These precipitation rates were 24 % higher than the long-term averages and 245 % higher than those over the 2011-2016 period of drought. In this study, we examined the occurrences of slopes failures near Los Angeles in response to high rainfall rates over 2016-2017. We composited time series of high-resolution Planetscope satellite images with resolutions of 3 - 4 m/pixel for 4 selected locations after reviewing 190,000 km2 area in total. We mapped the surface changes by comparing satellite images before and after the winter 2016-2017. Preliminary analysis using spectral bands highlighted the surface changes made by mudflows, landslides, lake levels and land developments. We compared these changes across 2016-2017 with those over a period of recent drought (2011-2016) to assess the influence of high rainfall rates on slope failures.

  7. Metabolic rates of benthic deep-sea decapod crustaceans decline with increasing depth primarily due to the decline in temperature

    NASA Astrophysics Data System (ADS)

    Childress, J. J.; Cowles, D. L.; Favuzzi, J. A.; Mickel, T. J.

    1990-06-01

    The oxygen consumption rates of 11 species of benthic deep-sea decapod crustaceans were measured at a variety of temperatures to test the hypothesis that the metabolic rates of benthic crustaceans decline with increasing depth of occurrence only to the extent explained by the decline in temperature with depth. The species were captured at depths between 150 and 2000m off Southern California using an epibenthic beam trawl equipped with a thermally protecting cod-end to bring the animals to the surface uncontaminated by sediment and at the depth temperature. The data, combined with those for six species of shallower-living crustaceans from California waters, showed a significant decline in oxygen consumption rate with increased species' depths of occurrence, when the measurements were made at temperatures appropriate to each species' depth range. There was no significant relation between wet weight and depth of occurrence in these species. When the data were adjusted to 10°C using a moderate temperature effect factor (corresponding to Q10 values of 2-2.3 depending on the species and temperature range), the significant relationship between oxygen consumption rate and depth was lost, indicating that the observed decline with depth was due to the decline in temperature with depth. When the relationship between metabolic rate and depth of occurrence for the most active (carideans and penaeid) species were compared (ANCOVA) with that for the rest of the species, the active species had significantly higher rates. By combining this data set with data from the literature for a wide variety of shallow-living benthic decapod crustaceans, it was possible to create a data set of 35 species in which the effects of temperature, minimum depth of occurrence and body mass could be separated by multiple linear regression. This demonstrated highly significant effects of size and temperature, but no significant effect of depth for the entire data set and for the data set excluding penaeids and carideans. In contrast, the carideans showed a significant effect of depth on metabolic rate. This is discussed in terms of the adaptive and selective factors responsible for the well-known decline in metabolic rates of midwater crustaceans and fishes, an effect which does exceed the effect of temperature. It is suggested that the typical pattern for deeper living animals may be that metabolic rates on average vary as a function of depth due primarily to variation in temperature, except for the visually orienting pelagic groups (cephalopods, crustaceans and fishes). For those benthic forms which are particularly visually oriented and/or partially pelagic some significant depth-related decline in metabolism beyond that due to the decline in temperature is expected.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xi, P. W.; Lawrence Livermore National Laboratory, Livermore, California 94550; Xu, X. Q.

    We demonstrate that the occurrence of Edge-Localized-Modes (ELM) crashes does not depend only on the linear peeling-ballooning threshold, but also relies on nonlinear processes. Wave-wave interaction constrains the growth time of a mode, thus inducing a shift in the criterion for triggering an ELM crash. An ELM crash requires the P-B growth rate to exceed a critical value γ>γ{sub c}, where γ{sub c} is set by 1/τ{sup ¯}{sub c}, and τ{sup ¯}{sub c} is the averaged mode phase coherence time. For 0

  9. Epidemiology of Parkinson disease in the city of Kolkata, India

    PubMed Central

    Das, S.K.; Misra, A.K.; Ray, B.K.; Hazra, A.; Ghosal, M.K.; Chaudhuri, A.; Roy, T.; Banerjee, T.K.; Raut, D.K.

    2010-01-01

    Objective: No well-designed longitudinal study on Parkinson disease (PD) has been conducted in India. Therefore, we planned to determine the prevalence, incidence, and mortality rates of PD in the city of Kolkata, India, on a stratified random sample through a door-to-door survey. Method: This study was undertaken between 2003 to 2007 with a validated questionnaire by a team consisting of 4 trained field workers in 3 stages. Field workers screened the cases, later confirmed by a specialist doctor. In the third stage, a movement disorders specialist undertook home visits and reviewed all surviving cases after 1 year from last screening. Information on death was collected through verbal autopsy. A nested case-control study (1:3) was also undertaken to determine putative risk factors. The rates were age adjusted to the World Standard Population. Result: A total population of 100,802 was screened. The age-adjusted prevalence rate (PR) and average annual incidence rate were 52.85/100,000 and 5.71/100,000 per year, respectively. The slum population showed significantly decreased PR with age compared with the nonslum population. The adjusted average annual mortality rate was 2.89/100,000 per year. The relative risk of death was 8.98. The case-control study showed that tobacco chewing protected and hypertension increased PD occurrence. Conclusion: This study documented lower prevalence and incidence of PD as compared with Caucasian and a few Oriental populations. The mortality rates were comparable. The decreased age-specific PR among slum populations and higher relative risk of death need further probing. GLOSSARY AAIR = average annual incidence rate; AAMR = average annual mortality rate; CI = confidence interval; FSQ = family screening questionnaire; ICC = intraclass correlation coefficient; IR = incidence rate; MD = movement disorder; NSSO = National Sample Survey Organization; OR = odds ratio; PD = Parkinson disease; PPS = parkinsonism plus syndrome; PR = prevalence rate; PRM = Poisson regression modeling; RR = relative risk; SP = secondary parkinsonism; VA = verbal autopsy. PMID:20938028

  10. Solar Modulation of the MJO on Intraseasonal Time Scales

    NASA Astrophysics Data System (ADS)

    Hood, L. L.

    2017-12-01

    During the last two years, several groups have reported evidence for an influence of the stratospheric quasi-biennial oscillation (QBO) on the boreal winter Madden-Julian Oscillation (MJO). Specifically, DJF mean MJO amplitudes are somewhat larger on average during the easterly QBO phase at 50 hPa (QBOE) than during the westerly phase (QBOW). A possible mechanism is decreased static stability in the tropical lowermost stratosphere caused by increased upwelling associated with the QBO mean meridional circulation during periods of easterly vertical wind shear. It has also been recently proposed that interannual variability of the boreal winter MJO is influenced by tropical upwelling changes associated with the 11-year solar cycle. The modulation is such that MJO amplitudes are especially large under QBOE/SMIN conditions and especially small under QBOW/SMAX conditions (Hood, GRL, 2017). Here, evidence is presented of a modulation of MJO amplitudes under solar maximum conditions by solar variability on the time scale of the solar rotation period (about 27 days). Specifically, normalized occurrence rates of MJO events with amplitudes greater than a chosen threshold are calculated as a function of phase lag relative to peaks in solar UV flux occurring on the solar rotational time scale. All MJO phases and four solar maximum periods are considered (1979-83; 1989-93; 1999-03; 2011-15). The data are further edited to eliminate periods with relatively weak UV variations. About 130 strong "cycles" remain after editing. When MJO events with amplitudes greater than 1.5 are considered, significant reductions of MJO occurrence rates and associated increases in static stability in the tropical lower stratosphere over the warm pool region are obtained several days following solar UV peaks. The reductions in occurrence rate occur during the December to May period when the MJO is most active and are largest when the QBO is in its easterly phase. For example, under the latter conditions, the mean occurrence rate for MJO amplitudes greater than 2 is reduced from the long-term mean of about 21 per cent to about 7 per cent 2 to 4 days following the UV peak, significant at 95 per cent confidence as estimated from Monte Carlo simulations. Conversely, mean occurrence rates are significantly increased five to ten days following solar UV minima.

  11. On the dynamical behaviour of low-frequency earthquake swarms prior to a dome collapse of Soufrière Hill volcano, Montserrat

    NASA Astrophysics Data System (ADS)

    Hammer, C.; Neuberg, J. W.

    2009-03-01

    A series of low-frequency earthquake swarms prior to a dome collapse on Soufrière Hills volcano, Montserrat, are investigated with the emphasis on event rate and amplitude behaviour. In a single swarm, the amplitudes of consecutive events tend to increase with time, while the rate of event occurrence accelerates initially and then decelerates toward the end of the swarm. However, when consecutive swarms are considered, the average event rates seem to follow the material failure law, and the time of the dome collapse can be successfully estimated using the inverse event rate. These patterns in amplitude and event rate are interpreted as fluctuations in magma ascent velocity, which result in both the generation of low-frequency events as well as cyclic ground deformation accompanying the swarm activity.

  12. Full-scale studies of factors related to coliform regrowth in drinking water.

    PubMed

    LeChevallier, M W; Welch, N J; Smith, D B

    1996-07-01

    An 18-month survey of 31 water systems in North America was conducted to determine the factors that contribute to the occurrence of coliform bacteria in drinking water. The survey included analysis of assimilable organic carbon (AOC), coliforms, disinfectant residuals, and operational parameters. Coliform bacteria were detected in 27.8% of the 2-week sampling periods and were associated with the following factors: filtration, temperature, disinfectant type and disinfectant level, AOC level, corrosion control, and operational characteristics. Four systems in the study that used unfiltered surface water accounted for 26.6% of the total number of bacterial samples collected but 64.3% (1,013 of 1,576) of the positive coliform samples. The occurrence of coliform bacteria was significantly higher when water temperatures were > 15 degrees C. For filtered systems that used free chlorine, 0.97% of 33,196 samples contained coliform bacteria, while 0.51% of 35,159 samples from chloraminated systems contained coliform bacteria. The average density of coliform bacteria was 35 times higher in free-chlorinated systems than in chloraminated water (0.60 CFU/100 ml for free-chlorinated water compared with 0.017 CFU/100 ml for chloraminated water). Systems that maintained dead-end free chlorine levels of < 0.2 mg/liter or monochloramine levels of < 0.5 mg/liter had substantially more coliform occurrences than systems that maintained higher disinfectant residuals. Free-chlorinated systems with AOC levels greater than 100 micrograms/liter had 82% more coliform-positive samples and 19 times higher coliform levels than free-chlorinated systems with average AOC levels less than 99 micrograms/liter. Systems that maintained a phosphate-based corrosion inhibitor and limited the amount of unlined cast iron pipe had fewer coliform bacteria. Several operational characteristics of the treatment process or the distribution system were also associated with increased rates of coliform occurrence. The study concludes that the occurrence of coliform bacteria within a distribution system is dependent upon a complex interaction of chemical, physical, operational, and engineering parameters. No one factor could account for all of the coliform occurrences, and one must consider all of the parameters described above in devising a solution to the regrowth problem.

  13. Full-scale studies of factors related to coliform regrowth in drinking water.

    PubMed Central

    LeChevallier, M W; Welch, N J; Smith, D B

    1996-01-01

    An 18-month survey of 31 water systems in North America was conducted to determine the factors that contribute to the occurrence of coliform bacteria in drinking water. The survey included analysis of assimilable organic carbon (AOC), coliforms, disinfectant residuals, and operational parameters. Coliform bacteria were detected in 27.8% of the 2-week sampling periods and were associated with the following factors: filtration, temperature, disinfectant type and disinfectant level, AOC level, corrosion control, and operational characteristics. Four systems in the study that used unfiltered surface water accounted for 26.6% of the total number of bacterial samples collected but 64.3% (1,013 of 1,576) of the positive coliform samples. The occurrence of coliform bacteria was significantly higher when water temperatures were > 15 degrees C. For filtered systems that used free chlorine, 0.97% of 33,196 samples contained coliform bacteria, while 0.51% of 35,159 samples from chloraminated systems contained coliform bacteria. The average density of coliform bacteria was 35 times higher in free-chlorinated systems than in chloraminated water (0.60 CFU/100 ml for free-chlorinated water compared with 0.017 CFU/100 ml for chloraminated water). Systems that maintained dead-end free chlorine levels of < 0.2 mg/liter or monochloramine levels of < 0.5 mg/liter had substantially more coliform occurrences than systems that maintained higher disinfectant residuals. Free-chlorinated systems with AOC levels greater than 100 micrograms/liter had 82% more coliform-positive samples and 19 times higher coliform levels than free-chlorinated systems with average AOC levels less than 99 micrograms/liter. Systems that maintained a phosphate-based corrosion inhibitor and limited the amount of unlined cast iron pipe had fewer coliform bacteria. Several operational characteristics of the treatment process or the distribution system were also associated with increased rates of coliform occurrence. The study concludes that the occurrence of coliform bacteria within a distribution system is dependent upon a complex interaction of chemical, physical, operational, and engineering parameters. No one factor could account for all of the coliform occurrences, and one must consider all of the parameters described above in devising a solution to the regrowth problem. PMID:8779557

  14. Association Between Hospital Performance on Patient Safety and 30-Day Mortality and Unplanned Readmission for Medicare Fee-for-Service Patients With Acute Myocardial Infarction.

    PubMed

    Wang, Yun; Eldridge, Noel; Metersky, Mark L; Sonnenfeld, Nancy; Fine, Jonathan M; Pandolfi, Michelle M; Eckenrode, Sheila; Bakullari, Anila; Galusha, Deron H; Jaser, Lisa; Verzier, Nancy R; Nuti, Sudhakar V; Hunt, David; Normand, Sharon-Lise T; Krumholz, Harlan M

    2016-07-12

    Little is known regarding the relationship between hospital performance on adverse event rates and hospital performance on 30-day mortality and unplanned readmission rates for Medicare fee-for-service patients hospitalized for acute myocardial infarction (AMI). Using 2009-2013 medical record-abstracted patient safety data from the Agency for Healthcare Research and Quality's Medicare Patient Safety Monitoring System and hospital mortality and readmission data from the Centers for Medicare & Medicaid Services, we fitted a mixed-effects model, adjusting for hospital characteristics, to evaluate whether hospital performance on patient safety, as measured by the hospital-specific risk-standardized occurrence rate of 21 common adverse event measures for which patients were at risk, is associated with hospital-specific 30-day all-cause risk-standardized mortality and unplanned readmission rates for Medicare patients with AMI. The unit of analysis was at the hospital level. The final sample included 793 acute care hospitals that treated 30 or more Medicare patients hospitalized for AMI and had 40 or more adverse events for which patients were at risk. The occurrence rate of adverse events for which patients were at risk was 3.8%. A 1% point change in the risk-standardized occurrence rate of adverse events was associated with average changes in the same direction of 4.86% points (95% CI, 0.79-8.94) and 3.44% points (95% CI, 0.19-6.68) for the risk-standardized mortality and unplanned readmission rates, respectively. For Medicare fee-for-service patients discharged with AMI, hospitals with poorer patient safety performance were also more likely to have poorer performance on 30-day all-cause mortality and on unplanned readmissions. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  15. Performance Analysis of Occurrences January 1, 2011-December 31, 2011

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ludwig, M

    2012-03-16

    This report documents the analysis of the occurrences during the period January 1, 2011 through December 31, 2011. The report compares LLNL occurrences by reporting criteria and significance category to see if LLNL is reporting occurrences along similar percentages as other DOE sites. The three-year trends are analyzed. It does not include the analysis of the causes or the lessons learned from the occurrences, as they are analyzed separately. The number and types of occurrences that LLNL reports to DOE varies over time. This variation can be attributed to normally occurring changes in frequency; DOE's or LLNL's heightened interest inmore » a particular subject area; changes in LLNL processes; or emerging problems. Since all of the DOE sites use the same reporting criteria, it is helpful to understand if LLNL is consistent with or diverging from reporting at other sites. This section compares the normalized number of occurrences reported by LLNL and other DOE sites. In order to compare LLNL occurrence reports to occurrence reports from other DOE sites, we normalized (or standardized) the data from the sites. DOE sites vary widely in their budgets, populations, and scope of work and these variations may affect reporting frequency. In addition, reports are required for a wide range of occurrence types, some of which may not be applicable to all DOE sites. For example, one occurrence reporting group is Group 3, Nuclear Safety Basis, and not all sites have nuclear operations. Because limited information is available for all sites, the sites were normalized based on best available information. Site effort hours were extracted from the DOE Computerized Accident Incident Reporting System (CAIRS) and used to normalize (or standardize) the number of occurrences by site. Effort hours are those hours that employees normally work and do not include vacation, holiday hours etc. Sites are responsible for calculating their effort hours and ensuring entry into CAIRS. Out of the 30 DOE sites that reported occurrences into ORPS during January 2011 through December 2011, 28 had effort hours available in CAIRS. Two sites had not submitted effort hours data to CAIRS as of the time data was pulled for this report. In those two cases, third quarter data was used as an estimate of fourth quarter data. The use of estimated data may introduce minor errors in the average, median, and Pearson calculations. Using the effort hours and the frequency of occurrences by site, a rate of occurrence frequency per 100 FTE workers was calculated. This rate is similar to the injury/illness frequency rate: the number of injury/illness cases per 100 FTE workers. To validate that this rate was appropriate to use, we compared the effort hours and the frequency of occurrences by site to determine if a relationship exists between the two, e.g. the more effort hours a site has, the more occurrences they tend to have. This hypothesis was tested using the Pearson Correlation Coefficient Test. The correlation coefficient measures the strength of the linear relationship between effort hours and occurrence frequency. The Pearson Correlation Coefficient Test will determine if the true correlation coefficient is equal to zero (no relationship exists), or if the correlation coefficient is not equal to zero (a relationship exists). Values approaching 1.00 show a more positive correlation. Simple linear regression was also used to display a trend line and to test if a one-way relationship exists between effort hours predicting the number of occurrences a site will have. Using the Pearson Correlation test, for the NNSA sites, effort hours and the number of occurrences are significantly and positively correlated with a correlation coefficient of 0.90, as was also seen in the previous report (correlation coefficient of 0.67). All DOE sites are positively correlated with a coefficient of 0.85. As the effort hours increase, so does the number of occurrences and vice versa. Based on the results of the simple linear regression, effort hours were found to predict the number of occurrences.« less

  16. [Prediction model of human-caused fire occurrence in the boreal forest of northern China].

    PubMed

    Guo, Fu-tao; Su, Zhang-wen; Wang, Guang-yu; Wang, Qiang; Sun, Long; Yang, Ting-ting

    2015-07-01

    The Chinese boreal forest is an important forest resource in China. However, it has been suffering serious disturbances of forest fires, which were caused equally by natural disasters (e.g., lightning) and human activities. The literature on human-caused fires indicates that climate, topography, vegetation, and human infrastructure are significant factors that impact the occurrence and spread of human-caused fires. But the studies on human-caused fires in the boreal forest of northern China are limited and less comprehensive. This paper applied the spatial analysis tools in ArcGIS 10.0 and Logistic regression model to investigate the driving factors of human-caused fires. Our data included the geographic coordinates of human-caused fires, climate factors during year 1974-2009, topographic information, and forest map. The results indicated that distance to railway (x1) and average relative humidity (x2) significantly impacted the occurrence of human-caused fire in the study area. The logistic model for predicting the fire occurrence probability was formulated as P= 1/[11+e-(3.026-0.00011x1-0.047x2)] with an accuracy rate of 80%. The above model was used to predict the monthly fire occurrence during the fire season of 2015 based on the HADCM2 future weather data. The prediction results showed that the high risk of human-caused fire occurrence concentrated in the months of April, May, June and August, while April and May had higher risk of fire occurrence than other months. According to the spatial distribution of possibility of fire occurrence, the high fire risk zones were mainly in the west and southwest of Tahe, where the major railways were located.

  17. Fog at the Guarulhos International Airport from 1951 to 2015

    NASA Astrophysics Data System (ADS)

    França, Gutemberg Borges; do Carmo, Luiz Felipe Rodrigues; de Almeida, Manoel Valdonel; Albuquerque Neto, Francisco Leite

    2018-02-01

    This paper presents and discusses the fog occurrences before and after the construction of the Guarulhos International Airport, using data from 1951 to 2015. The analysis showed the following: (1) a total of 19,816 h of fog were registered. (2) The minimum average, mean and maximum average of the fog temperature had significantly increased after the airport was constructed from 1.2 to 6.9, 12.1 to 14.5 and 20.2 to 20.7 °C, respectively, due to the urban development around the airport during the study period. (3) The average fog hours per year decreased by approximately 73.1%, i.e., from 492 ± 84.45 to 132 ± 54.51 h per year. (4) Most of the fog events occurred due to longwave cooling on clear nights with relatively low wind speeds (characterizing radiation fog), with over 65% having duration of 2 h and occurring in the early hours of the day during March-September period. (5) The maximum probability of fog occurrence dropped about 10% from before to after the construction of the airport. Finally, two fog events are investigated using data collected during the fog evolution using atmospheric sounding profiles (from an acoustic sounder) and automatic meteorological stations and preliminary results showed that the values of cooling rate and turbulent kinetic energy play key roles in the onset and growth-dissipation phases of the fog, respectively.

  18. [Occurrence of quinolone and sulfonamide antibiotics in swine and cattle manures from large-scale feeding operations of Guangdong Province].

    PubMed

    Tai, Yi-Ping; Luo, Xiao-Dong; Mo, Ce-Hui; Li, Yan-Wen; Wu, Xiao-Lian; Liu, Xing-Yue

    2011-04-01

    The occurrence and distribution of four quinolones and four sulfonamides in swine and cattle feces sampled from twenty large-scale feeding operations in different areas of Guangdong province were detected using solid phase extraction (SPE) and high performance liquid chromatography (HPLC). Quinolone and sulfonamide compounds were observed in all pig dung samples. Their total concentrations ranged from 24.5 microg/kg to 1516.2 microg/kg (F. W.) with an average of 581.0 microg/kg and ranged from 1925.9-13399.5 microg/kg with an average of 4403.9 microg/kg respectively. The dominant compounds in pig feces were ciprofloxacin and enrofloxacin for quinolones and sulfamerazine and sulfamethoxazole for sulfonamides. Quinolone compounds which dominated with norfloxacin and ciprofloxacin were also observed in all cattle dung samples, its total concentrations ranged from 73.2 microg/kg to 1328.0 microg/kg which averaged 572.9 microg/kg. While the positive rates of sulfonamide compounds detected in cattle dung samples were above 90%, predominated by sulfamethoxazole and sulfamerazine. Concentration and distribution of both quinolone and sulfonamide compounds in swine and cattle dungs of different feeding operations varied greatly. Relatively high concentrations of the two kinds of antibiotics were found in both swine and cattle dungs from Guangzhou area, while sulfameter and sulfamethazine in cattle dungs from Foshan and Shenzhen areas were below the limit of detection.

  19. Sudden cardiac death rates in an Australian population: a data linkage study.

    PubMed

    Feng, Jia-Li; Hickling, Siobhan; Nedkoff, Lee; Knuiman, Matthew; Semsarian, Christopher; Ingles, Jodie; Briffa, Tom G

    2015-11-01

    The aim of the present study was to develop criteria to identify sudden cardiac death (SCD) and estimate population rates of SCD using administrative mortality and hospital morbidity records in Western Australia. Four criteria were developed using place, death within 24 h, principal and secondary diagnoses, underlying and associated cause of death, and/or occurrence of a post mortem to identify SCD. Average crude, age-standardised and age-specific rates of SCD were estimated using population person-linked administrative data. In all, 9567 probable SCDs were identified between 1997 and 2010, with one-third aged ≥ 35 years having no prior admission for cardiovascular disease. SCD was more frequent in men (62.1%). The estimated average annual crude SCD rate for the period was 34.6 per 100 000 person-years with an average annual age-standardised rate of 37.8 per 100 000 person-years. Age-specific standardised rates were 1.1 per 100 000 person-years and 70.7 per 100 000 person-years in people aged 1-34 and ≥ 35 years, respectively. Ischaemic heart disease (IHD) was recorded as the underlying cause of death in approximately 80% of patients aged ≥ 35 years, followed by valvular heart disease and heart failure. IHD was the most common cause of death in those aged 1-34 years, followed by unspecified cardiomyopathy and dysrhythmias. Administrative morbidity and mortality data can be used to estimate rates of SCD and therefore provide a suitable methodology for monitoring SCD over time. The findings highlight the magnitude of SCD and its potential for public health prevention.

  20. Aftershock occurrence rate decay for individual sequences and catalogs

    NASA Astrophysics Data System (ADS)

    Nyffenegger, Paul A.

    One of the earliest observations of the Earth's seismicity is that the rate of aftershock occurrence decays with time according to a power law commonly known as modified Omori-law (MOL) decay. However, the physical reasons for aftershock occurrence and the empirical decay in rate remain unclear despite numerous models that yield similar rate decay behavior. Key problems in relating the observed empirical relationship to the physical conditions of the mainshock and fault are the lack of studies including small magnitude mainshocks and the lack of uniformity between studies. We use simulated aftershock sequences to investigate the factors which influence the maximum likelihood (ML) estimate of the Omori-law p value, the parameter describing aftershock occurrence rate decay, for both individual aftershock sequences and "stacked" or superposed sequences. Generally the ML estimate of p is accurate, but since the ML estimated uncertainty is unaffected by whether the sequence resembles an MOL model, a goodness-of-fit test such as the Anderson-Darling statistic is necessary. While stacking aftershock sequences permits the study of entire catalogs and sequences with small aftershock populations, stacking introduces artifacts. The p value for stacked sequences is approximately equal to the mean of the individual sequence p values. We apply single-link cluster analysis to identify all aftershock sequences from eleven regional seismicity catalogs. We observe two new mathematically predictable empirical relationships for the distribution of aftershock sequence populations. The average properties of aftershock sequences are not correlated with tectonic environment, but aftershock populations and p values do show a depth dependence. The p values show great variability with time, and large values or changes in p sometimes precedes major earthquakes. Studies of teleseismic earthquake catalogs over the last twenty years have led seismologists to question seismicity models and aftershock sequence decay for deep sequences. For seven exceptional deep sequences, we conclude that MOL decay adequately describes these sequences, and little difference exists compared to shallow sequences. However, they do include larger aftershock populations compared to most deep sequences. These results imply that p values for deep sequences are larger than those for intermediate depth sequences.

  1. [Effects of N application on wheat powdery mildew occurrence, nitrogen accumulation and allocation in intercropping system].

    PubMed

    Zhu, Jin Hui; Dong, Yan; Xiao, Jing Xiu; Zheng, Yi; Tang, Li

    2017-12-01

    The main objective of this field experiment was to study the effects of wheat and faba bean intercropping on occurrence of wheat powdery mildew, nitrogen content, accumulation and allocation of wheat plant at 4 nitrogen levels of N 0 (0 kg·hm -2 ), N 1 (112.5 kg·hm -2 ), N 2 (225 kg·hm -2 ), N 3 (337.5 kg·hm -2 ), and to explore the relationship between N content, accumulation, allocation and the occurrence of wheat powdery mildew. The results showed that both monocropped and intercropped wheat yields increased with nitrogen application, with the highest yields of monocropped and intercropped wheat being 4146 kg·hm -2 and 4679 kg·hm -2 at N 2 le-vel, respectively. The occurrence and development of wheat powdery mildew become more severe with the increase of N application and area under disease progression curve (AUDPC) were averagely increased by 39.6%-55.6%(calculated with disease incidence, DI) and 92.5%-217.0% (calculated with disease severity index, DSI) with N 1 , N 2 and N 3 treatments. The disease severity index was more affected by nitrogen regulation than by disease incidence. The nitrogen content and accumulation of wheat plant were significantly increased by 8.4%-51.6% and 19.7%-133.7% with nitrogen application, but there was no significant effect on N allocation ratio. Compared with monocropped wheat, yield of intercropped wheat was averagely increased by 12%, whereas, the AUDPC(DI) and AUDPC(DSI) of intercropped wheat were averagely decreased by 11.5% and 30.7%, respectively. The control effect of the disease severity index by intercropping was better than disease incidence. The nitrogen content, accumulation and nitrogen allocation ratio in intercropped wheat leaves were significantly decreased by 6.6%-12.5%, 1.4%-6.9% and 9.0%-15.5% respectively at the peak infection stage of powdery mildew. Overall findings showed that the maximum rate of nitrogen application for wheat should not exceed 225 kg·hm -2 when taking into account both disease control and yield effect.

  2. The level crossing rates and associated statistical properties of a random frequency response function

    NASA Astrophysics Data System (ADS)

    Langley, Robin S.

    2018-03-01

    This work is concerned with the statistical properties of the frequency response function of the energy of a random system. Earlier studies have considered the statistical distribution of the function at a single frequency, or alternatively the statistics of a band-average of the function. In contrast the present analysis considers the statistical fluctuations over a frequency band, and results are obtained for the mean rate at which the function crosses a specified level (or equivalently, the average number of times the level is crossed within the band). Results are also obtained for the probability of crossing a specified level at least once, the mean rate of occurrence of peaks, and the mean trough-to-peak height. The analysis is based on the assumption that the natural frequencies and mode shapes of the system have statistical properties that are governed by the Gaussian Orthogonal Ensemble (GOE), and the validity of this assumption is demonstrated by comparison with numerical simulations for a random plate. The work has application to the assessment of the performance of dynamic systems that are sensitive to random imperfections.

  3. External cause-specific summaries of occupational fatal injuries. Part II: an analysis of years of potential life lost.

    PubMed

    Bailer, A John; Bena, James F; Stayner, Leslie T; Halperin, William E; Park, Robert M

    2003-03-01

    Fatal injury surveillance data provide an opportunity to assess the impact of occupational injuries and may indicate which industries or occupations are appreciably more hazardous than others, and thus should be given priority in public health intervention. Fatalities from the National Traumatic Occupational Fatality surveillance system served as the basis for examining external cause (E-code) specific impact summaries. Years of potential life lost (YPLL) were calculated for fatal injuries in the years 1983-1994. Industries and occupations were compared with respect to frequency of fatal injuries. In addition, injuries in categories of external causes are examined across all industries and occupations. Machinery, electric current, homicide, falls, and transportation-related are the external cause groups highlighted by high frequency/rate of occurrence. Electric current event groups are also characterized by high average YPLL. Poisoning, conflagration, and lightning were also identified in several occupations as having high associated average YPLL. The external-cause-specific analysis of average YPLL identified industries and occupations where, on average, younger workers were dying in fatal injuries. Noteworthy in this assessment were homicides and falls. The YPLL measure coupled with more commonly employed indices (e.g., rates) may provide a fuller description of the impact of occupational fatal injuries.

  4. Lexical association and false memory for words in two cultures.

    PubMed

    Lee, Yuh-shiow; Chiang, Wen-Chi; Hung, Hsu-Ching

    2008-01-01

    This study examined the relationship between language experience and false memory produced by the DRM paradigm. The word lists used in Stadler, et al. (Memory & Cognition, 27, 494-500, 1999) were first translated into Chinese. False recall and false recognition for critical non-presented targets were then tested on a group of Chinese users. The average co-occurrence rate of the list word and the critical word was calculated based on two large Chinese corpuses. List-level analyses revealed that the correlation between the American and Taiwanese participants was significant only in false recognition. More importantly, the co-occurrence rate was significantly correlated with false recall and recognition of Taiwanese participants, and not of American participants. In addition, the backward association strength based on Nelson et al. (The University of South Florida word association, rhyme and word fragment norms, 1999) was significantly correlated with false recall of American participants and not of Taiwanese participants. Results are discussed in terms of the relationship between language experiences and lexical association in creating false memory for word lists.

  5. A statistical model to estimate the local vulnerability to severe weather

    NASA Astrophysics Data System (ADS)

    Pardowitz, Tobias

    2018-06-01

    We present a spatial analysis of weather-related fire brigade operations in Berlin. By comparing operation occurrences to insured losses for a set of severe weather events we demonstrate the representativeness and usefulness of such data in the analysis of weather impacts on local scales. We investigate factors influencing the local rate of operation occurrence. While depending on multiple factors - which are often not available - we focus on publicly available quantities. These include topographic features, land use information based on satellite data and information on urban structure based on data from the OpenStreetMap project. After identifying suitable predictors such as housing coverage or local density of the road network we set up a statistical model to be able to predict the average occurrence frequency of local fire brigade operations. Such model can be used to determine potential hotspots for weather impacts even in areas or cities where no systematic records are available and can thus serve as a basis for a broad range of tools or applications in emergency management and planning.

  6. Rumen clearance rates in relation to the occurrence of alfalfa bloat in cattle. 1. Passage of water-soluble markers.

    PubMed

    Majak, W; Hall, J W; Rode, L M; Kalnin, C M

    1986-06-01

    Ruminal chlorophyll and rates of passage of two water-soluble markers were simultaneously determined in cattle with different susceptibilities to alfalfa bloat. The markers showed a slower rate of passage from the rumens of more susceptible cattle where the average half-lives for cobalt-ethylenediaminetetraacetic acid and chromium-ethylenediaminetetraacetic acid were 12 to 17 h. Average half-life of the markers was 8 h in the rumens of the less susceptible animals. In agreement, chloroplast particles in the liquid phase of rumen contents showed greater accumulation in animals susceptible to bloat, but many more observations were required to detect differences in chlorophyll among animals. This was partly due to the unhomogeneous dispersion of chloroplast fragments in the reticulorumen compared with the uniform distribution of the inert markers. Differences in rumen volumes (estimated from the quantity of marker administered and its initial concentration) were detected among animals, but these did not show a relationship to bloat susceptibility. In vitro studies indicated that alfalfa chloroplast particles were not readily degraded by rumen microorganisms. Our results support earlier conclusions on slower rates of salivation for cattle that bloat compared with those that do not.

  7. Vortex reconnection rate, and loop birth rate, for a random wavefield

    NASA Astrophysics Data System (ADS)

    Hannay, J. H.

    2017-04-01

    A time dependent, complex scalar wavefield in three dimensions contains curved zero lines, wave ‘vortices’, that move around. From time to time pairs of these lines contact each other and ‘reconnect’ in a well studied manner, and at other times tiny loops of new line appear from nowhere (births) and grow, or the reverse, existing loops shrink and disappear (deaths). These three types are known to be the only generic events. Here the average rate of their occurrences per unit volume is calculated exactly for a Gaussian random wavefield that has isotropic, stationary statistics, arising from a superposition of an infinity of plane waves in different directions. A simplifying ‘axis fixing’ technique is introduced to achieve this. The resulting formulas are proportional to the standard deviation of angular frequencies, and depend in a simple way on the second and fourth moments of the power spectrum of the plane waves. Reconnections turn out to be more common than births and deaths combined. As an expository preliminary, the case of two dimensions, where the vortices are points, is studied and the average rate of pair creation (and likewise destruction) per unit area is calculated.

  8. A hail climatology in Mongolia

    NASA Astrophysics Data System (ADS)

    Lkhamjav, Jambajamts; Jin, Han-Gyul; Lee, Hyunho; Baik, Jong-Jin

    2017-11-01

    The temporal and spatial characteristics of hail frequency in Mongolia are examined using the hail observation data from 61 meteorological observatories for 1984-2013. The annual number of hail days averaged over all observatories and the entire period is 0.74. It exhibits a decreasing trend, particularly since 1993 with a rate of decrease of 0.214 per decade. Hail occurrence is concentrated in summer, with 72% of the total hail days occurring in June, July, and August. Moreover, hail occurrence is concentrated in the afternoon and early evening, with 89% of the total hail events occurring between 1200 and 2100 local standard time (LST). Spatially, observatories where relatively frequent hail events are observed are concentrated in the north central region where almost all of the land is mountainous or covered by grassland, whereas relatively less frequent hail events are observed in the southern desert region. The relationship between hail frequency and thermodynamic factors including the convective available potential energy (CAPE), the temperature lapse rate between 700 and 500 hPa, the water vapor mixing ratio averaged over the lowest 100 hPa layer, and the freezing-level height is examined using the ERA-Interim reanalysis data. It is found that in summer, CAPE and the low-level water vapor mixing ratio are larger on hail days than on all days, but there is no clear relationship between hail frequency and the 700-500 hPa temperature lapse rate. It is also found that annually, CAPE and the low-level water vapor mixing ratio decrease, while the freezing-level height increases, which seems to be responsible for the annually decreasing trend of hail frequency in Mongolia.

  9. A hybrid NIRS-EEG system for self-paced brain computer interface with online motor imagery.

    PubMed

    Koo, Bonkon; Lee, Hwan-Gon; Nam, Yunjun; Kang, Hyohyeong; Koh, Chin Su; Shin, Hyung-Cheul; Choi, Seungjin

    2015-04-15

    For a self-paced motor imagery based brain-computer interface (BCI), the system should be able to recognize the occurrence of a motor imagery, as well as the type of the motor imagery. However, because of the difficulty of detecting the occurrence of a motor imagery, general motor imagery based BCI studies have been focusing on the cued motor imagery paradigm. In this paper, we present a novel hybrid BCI system that uses near infrared spectroscopy (NIRS) and electroencephalography (EEG) systems together to achieve online self-paced motor imagery based BCI. We designed a unique sensor frame that records NIRS and EEG simultaneously for the realization of our system. Based on this hybrid system, we proposed a novel analysis method that detects the occurrence of a motor imagery with the NIRS system, and classifies its type with the EEG system. An online experiment demonstrated that our hybrid system had a true positive rate of about 88%, a false positive rate of 7% with an average response time of 10.36 s. As far as we know, there is no report that explored hemodynamic brain switch for self-paced motor imagery based BCI with hybrid EEG and NIRS system. From our experimental results, our hybrid system showed enough reliability for using in a practical self-paced motor imagery based BCI. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Impulsive signals in the night ionosphere of Venus - Comparison of results obtained below the local electron gyro frequency with those above

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Von Dornum, M.; Scarf, F. L.

    1990-01-01

    Impulsive VLF signals at low altitudes in the night ionosphere of Venus occur both above and below the electron gyro frequency. The strength of the magnetic field has a very strong influence on the occurrence rates of these impulsive emissions at all frequencies. Above about one-quarter of the local electron gyro frequency the waves occur most frequently for strong magnetic fields and much less frequently for weak fields. However, below about one-quarter of the electron gyro frequency, the occurrence rate is much less sensitive to field strength. At all frequencies the occurrence rate depends little on the direction of the magnetic field. The occurrence rate is strongly dependent on local time especially above the electron gyro frequency. Here, the occurrence rate peaks sharply at 2100 LT. Below the local electron gyro frequency the occurrence rate also shows a maximum near 2100 LT but decreases much more slowly with increasing local time. The rate of occurrence of low frequency signals varies little with altitude but the occurrence of the higher frequency signals decreases rapidly. These properties are consistent with a broadband source of VLF waves in the Venus atmosphere such as would be provided by intracloud lightning.

  11. Moonquakes and lunar tectonism results from the Apollo passive seismic experiment.

    NASA Technical Reports Server (NTRS)

    Latham, G.; Ewing, M.; Dorman, J.; Lammlein, D.; Press, F.; Toksoz, N.; Sutton, G.; Duennebier, F.; Nakamura, Y.

    1972-01-01

    The natural seismicity of the moon appears to be very low relative to that of the earth. However, moonquakes do occur. They are detected by the stations of the Apollo seismic network at an average rate of 1800/yr at Station 14 and at lower rates at Stations 12 and 15. All of the moonquakes are small, and in the few cases for which the foci have been located, they occur at great depth (about 800 km). The frequency of occurrence of moonquakes is strongly correlated with lunar tides. The dynamic processes that generate quakes are clearly much less vigorous within the moon than they are within the earth.

  12. Occurrence of nitrosamines and their precursors in drinking water systems around mainland China.

    PubMed

    Bei, Er; Shu, Yuanyuan; Li, Shixiang; Liao, Xiaobin; Wang, Jun; Zhang, Xiaojian; Chen, Chao; Krasner, Stuart

    2016-07-01

    N-Nitrosamines (NAs) in drinking water have attracted considerable attention in recent years due to their high carcinogenicity, frequent occurrence, and their potential regulation. During the past three years, we have collected about 164 water samples of finished water, tap water, and source water from 23 provinces, 44 cities from large cities to small towns, and 155 sampling points all over China. The occurrence of NAs in the finished and tap water was much higher in China than that in the U.S. Nine NAs were measured and NDMA had the highest concentration. The occurrence of NDMA was in 33% of the finished waters of water treatment plants and in 41% of the tap waters. The average NDMA concentration in finished and tap waters was 11 and 13 ng/L, respectively. Formation potentials (FPs) of source waters were examined with an average NDMA FP of 66 ng/L. Large variations in NA occurrence were observed geographically in China and temporally in different seasons. The Yangtze River Delta area, one sub-area in East China, had the highest concentrations of NAs, where the average NDMA concentrations in the finished and tap water were 27 and 28.5 ng/L, respectively, and the average NDMA FP in the source water was 204 ng/L. NA control may be achieved by applying breakpoint free chlorination and/or advanced treatment of ozone - granular activated carbon process to remove the NA precursors before disinfection. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Investigation of the Performance of Safety Systems for Protection of the Elderly

    PubMed Central

    Augenstein, J.; Digges, K; Bahouth, G.; Dalmotas, D.; Perdeck, E.; Stratton, J.

    2005-01-01

    This study investigates injury occurrence for belted occupants as a function of age. An analysis of NASS/CDS 1997–2003 data was conducted to determine crash involvement rates and injury rates for front seat occupants versus mean occupant age. In frontal and near-side crashes, the average age of MAIS 3+ belted front seat occupants injured in crashes less severe than 15 mph is of the order of 50 years. The average age of the population exposed to crashes less severe than 15 mph is under 40 years old. The crash exposure and frequency if injuries to the elderly were both found to be the highest in low severity crashes. The chest is the most frequent body region injured for the elderly. These findings suggest the need for more benign safety systems to protect the elderly in low severity crashes. Design of safety systems for the elderly should give priority to reducing the chest loading in low severity frontal and near-side crashes. PMID:16179159

  14. Mercury - Its occurrence and economic trends

    USGS Publications Warehouse

    Bailey, Edgar H.; Smith, Roscoe M.

    1964-01-01

    price will be a predictable increase in production. If the price averages $300 a flask for 1 year or more, annual production may increase to a rate of 30,000-35,000 flasks in 1966 or 1967. If the price averages $400 a flask, production may increase to 45,000-50,000 flasks a year after a timelag of two or three years. New ore bodies would have to be found however, to attain these rates of production, and the mining of lower grade ores would be needed to sustain them for more than a few years. By 1966 the U.S. economy will require at least 67 000 flasks, and the domestic demand for mercury thereafter will continue to increase. The probability that domestic mines will continue to supply a fourth or more of the domestic consumption is dependent upon the price of mercury for the next few years. The outlook for the long-term supply is reassuring, but it is dependent, not only upon price, but upon continued progress in new techniques of discovery.

  15. Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery.

    PubMed

    Briggs, Patricia; Hawrylack, Helen; Mooney, Ruth

    2016-07-01

    Postoperative nausea is a common occurrence that is very uncomfortable for patients and may result in complications including pain, strain at the surgical site, aspiration, and possible dehiscence. Antiemetics used to manage the nausea cause many adverse reactions, such as dysrhythmias and/or drowsiness resulting in an unwillingness to ambulate or perform deep-breathing exercises. Previous studies have reported a decrease in nausea following the use of peppermint oil. Researchers obtained informed consent from 123 patients for this study; 34 (28%) of them experienced nausea and were offered a nasal inhaler that contained peppermint oil. The average nausea rating before the use of peppermint oil was 3.29 (SD, 1.0) on a scale of 0 to 5, with 5 being the greatest nausea. Two minutes later, the average nausea rating was 1.44 (SD, 1.3). Using paired t-tests, these differences were found to be statistically significant (P = 0.000). The researchers concluded that peppermint oil inhalation is a viable first-line treatment for nausea in postoperative cardiac surgery patients.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hepler, K.R.; Hansen, P.A.; Bernard, D.R.

    Five emigrating populations of Dolly Varden and cutthroat trout were intercepted in 1989-1991 during seaward migration to Prince William Sound following the Exxon Valdez oil spill; two into the spill area, three into non-spill areas. Study populations were comprised of tagged adults and subadults. Survival rates were estimated with log-linear models of capture histories of tagged fish. We used a two-stage simulation based on bootstrapping and Monte Carlo techniques to compare average survival rates in study populations that were and were not associated with spilled oil. Growth and survival rates were significantly lower in study populations associated with spilled oil.more » Results are consistent with the occurrence of a deleterious impact on growth and survival of emigrating species, although unable to be confirmed as results emanated from observation, not experiment.« less

  17. The day-to-day occurrence of equatorial plasma bubbles measured from Vanimo, Papua New Guinea

    NASA Astrophysics Data System (ADS)

    Carter, B. A.; Yizengaw, E.; Francis, M.; Terkildsen, M. B.; Marshall, R. A.; Norman, R.; Zhang, K.

    2013-12-01

    An analysis of the occurrence of Equatorial Plasma Bubbles (EPBs) detected using a ground-based Global Positioning System (GPS) receiver located at Vanimo in South-east Asia will be presented. The 3-year (2000-2002) dataset employed shows that the EPB occurrence maximizes (minimizes) during the equinoxes (solstices), in good agreement with previous findings. The low-latitude ionosonde station at Vanimo is used in conjunction with the GPS receiver in an analysis of the day-to-day EPB occurrence variability during the equinox period. A superposed epoch analysis of the ionosonde data reveals that the height, and the change in height, of the F layer is 1 standard deviation (1σ) larger on the days for which EPBs were detected, compared to non-EPB days. These results are interpreted using the generalized Rayleigh-Taylor (R-T) plasma instability growth rate, for which stronger upward drift of the lower-altitude F-layer plasma promotes faster growth of EPBs after sunset. These results are then compared to the results of the Thermosphere Ionosphere Electrodynamic General Circulation Model (TIEGCM), which surprisingly show strong similarities to the observations, despite only using geomagnetic and solar activity inputs. The TIEGCM is also used to directly calculate the hourly flux-tube integrated R-T growth rate. A superposed epoch analysis reveals that the modeled R-T growth rate is a little less than 1σ higher on average for EPB days compared to non-EPB days. The implication of this result is that the TIEGCM generates almost enough day-to-day variability in order to account for the day-to-day EPB occurrence observed during the equinox. This result isn't necessarily expected due to the model's limited altitude coverage of 100-700 km (depending on solar activity) and the lack of ionospheric observation inputs. It is thought that the remaining variability could originate from either lower altitudes (e.g. atmospheric gravity waves from the troposphere) or from higher altitudes (resulting from coupling with the magnetosphere and solar wind), or potentially both. It is concluded that the continuing advancement of numerical modeling of the thermosphere and ionosphere, coupled with altitudes above and below, is required to better understand the day-to-day EPB occurrence.

  18. Foreshock occurrence before large earthquakes

    USGS Publications Warehouse

    Reasenberg, P.A.

    1999-01-01

    Rates of foreshock occurrence involving shallow M ??? 6 and M ??? 7 mainshocks and M ??? 5 foreshocks were measured in two worldwide catalogs over ???20-year intervals. The overall rates observed are similar to ones measured in previous worldwide and regional studies when they are normalized for the ranges of magnitude difference they each span. The observed worldwide rates were compared to a generic model of earthquake clustering based on patterns of small and moderate aftershocks in California. The aftershock model was extended to the case of moderate foreshocks preceding large mainshocks. Overall, the observed worldwide foreshock rates exceed the extended California generic model by a factor of ???2. Significant differences in foreshock rate were found among subsets of earthquakes defined by their focal mechanism and tectonic region, with the rate before thrust events higher and the rate before strike-slip events lower than the worldwide average. Among the thrust events, a large majority, composed of events located in shallow subduction zones, had a high foreshock rate, while a minority, located in continental thrust belts, had a low rate. These differences may explain why previous surveys have found low foreshock rates among thrust events in California (especially southern California), while the worldwide observations suggests the opposite: California, lacking an active subduction zone in most of its territory, and including a region of mountain-building thrusts in the south, reflects the low rate apparently typical for continental thrusts, while the worldwide observations, dominated by shallow subduction zone events, are foreshock-rich. If this is so, then the California generic model may significantly underestimate the conditional probability for a very large (M ??? 8) earthquake following a potential (M ??? 7) foreshock in Cascadia. The magnitude differences among the identified foreshock-mainshock pairs in the Harvard catalog are consistent with a uniform distribution over the range of observation.

  19. Medium scale traveling ionospheric disturbances observed by detrended total electron content maps over South-Southeast of Brazil

    NASA Astrophysics Data System (ADS)

    Takahashi, H.; Figueiredo, C. A. O. B.; Wrasse, C. M.; Otsuka, Y.; Shiokawa, K.; Barros, D.

    2017-12-01

    Medium Scale Traveling Ionospheric Disturbances (MSTIDs) were studied using detrended Total Electron Content (dTEC) maps and keograms over South-Southeast of Brazil during the period from December 2012 to February 2016. In total 826 MSTIDs were observed and they present average values of horizontal wavelength, period, and horizontal phase velocity of 445.19 ± 106.70 km, 23.58 ± 3.65 min e 322.68 ± 80.95 m/s, respectively. The direction of propagation presented anisotropy depending on the season. In addition, the occurrences of MSTIDs were during the daytime between 11-15 LT in winter and other seasons near to solar terminator (17-19 LT). Furthermore, the seasonality of MSTIDs has a higher occurrence rate in winter. The MSTIDs characteristics also suggest that gravity wave activities in the thermosphere, mesosphere and troposphere could play an important role in generating the MSTIDs.

  20. Using satellite fire detection to calibrate components of the fire weather index system in Malaysia and Indonesia.

    PubMed

    Dymond, Caren C; Field, Robert D; Roswintiarti, Orbita; Guswanto

    2005-04-01

    Vegetation fires have become an increasing problem in tropical environments as a consequence of socioeconomic pressures and subsequent land-use change. In response, fire management systems are being developed. This study set out to determine the relationships between two aspects of the fire problems in western Indonesia and Malaysia, and two components of the Canadian Forest Fire Weather Index System. The study resulted in a new method for calibrating components of fire danger rating systems based on satellite fire detection (hotspot) data. Once the climate was accounted for, a problematic number of fires were related to high levels of the Fine Fuel Moisture Code. The relationship between climate, Fine Fuel Moisture Code, and hotspot occurrence was used to calibrate Fire Occurrence Potential classes where low accounted for 3% of the fires from 1994 to 2000, moderate accounted for 25%, high 26%, and extreme 38%. Further problems arise when there are large clusters of fires burning that may consume valuable land or produce local smoke pollution. Once the climate was taken into account, the hotspot load (number and size of clusters of hotspots) was related to the Fire Weather Index. The relationship between climate, Fire Weather Index, and hotspot load was used to calibrate Fire Load Potential classes. Low Fire Load Potential conditions (75% of an average year) corresponded with 24% of the hotspot clusters, which had an average size of 30% of the largest cluster. In contrast, extreme Fire Load Potential conditions (1% of an average year) corresponded with 30% of the hotspot clusters, which had an average size of 58% of the maximum. Both Fire Occurrence Potential and Fire Load Potential calibrations were successfully validated with data from 2001. This study showed that when ground measurements are not available, fire statistics derived from satellite fire detection archives can be reliably used for calibration. More importantly, as a result of this work, Malaysia and Indonesia have two new sources of information to initiate fire prevention and suppression activities.

  1. Long-term population dynamics of a managed burrowing owl colony

    USGS Publications Warehouse

    Barclay, John H.; Korfanta, Nicole M.; Kauffman, Matthew J.

    2011-01-01

    We analyzed the population dynamics of a burrowing owl (Athene cunicularia) colony at Mineta San Jose International Airport in San Jose, California, USA from 1990-2007. This colony was managed by using artificial burrows to reduce the occurrence of nesting owls along runways and within major airport improvement projects during the study period. We estimated annual reproduction in natural and artificial burrows and age-specific survival rates with mark-recapture techniques, and we estimated the relative contribution of these vital rates to population dynamics using a life table response experiment. The breeding colony showed 2 distinct periods of change: high population growth from 7 nesting pairs in 1991 to 40 pairs in 2002 and population decline to 17 pairs in 2007. Reproduction was highly variable: annual nesting success (pairs that raised =1 young) averaged 79% and ranged from 36% to 100%, whereas fecundity averaged 3.36 juveniles/pair and ranged from 1.43 juveniles/pair to 4.54 juveniles/pair. We estimated annual adult survival at 0.710 during the period of colony increase from 1996 to 2001 and 0.465 during decline from 2002 to 2007, but there was no change in annual survival of juveniles between the 2 time periods. Long-term population growth rate (lambda) estimated from average vital rates was lambdaa=1.072 with lambdai=1.288 during colony increase and lambdad=0.921 (DELTA lambda=0.368) during decline. A life table response experiment showed that change in adult survival rate during increasing and declining phases explained more than twice the variation in growth rate than other vital rates. Our findings suggest that management and conservation of declining burrowing owl populations should address factors that influence adult survival.

  2. Slow but not low: genomic comparisons reveal slower evolutionary rate and higher dN/dS in conifers compared to angiosperms.

    PubMed

    Buschiazzo, Emmanuel; Ritland, Carol; Bohlmann, Jörg; Ritland, Kermit

    2012-01-20

    Comparative genomics can inform us about the processes of mutation and selection across diverse taxa. Among seed plants, gymnosperms have been lacking in genomic comparisons. Recent EST and full-length cDNA collections for two conifers, Sitka spruce (Picea sitchensis) and loblolly pine (Pinus taeda), together with full genome sequences for two angiosperms, Arabidopsis thaliana and poplar (Populus trichocarpa), offer an opportunity to infer the evolutionary processes underlying thousands of orthologous protein-coding genes in gymnosperms compared with an angiosperm orthologue set. Based upon pairwise comparisons of 3,723 spruce and pine orthologues, we found an average synonymous genetic distance (dS) of 0.191, and an average dN/dS ratio of 0.314. Using a fossil-established divergence time of 140 million years between spruce and pine, we extrapolated a nucleotide substitution rate of 0.68 × 10(-9) synonymous substitutions per site per year. When compared to angiosperms, this indicates a dramatically slower rate of nucleotide substitution rates in conifers: on average 15-fold. Coincidentally, we found a three-fold higher dN/dS for the spruce-pine lineage compared to the poplar-Arabidopsis lineage. This joint occurrence of a slower evolutionary rate in conifers with higher dN/dS, and possibly positive selection, showcases the uniqueness of conifer genome evolution. Our results are in line with documented reduced nucleotide diversity, conservative genome evolution and low rates of diversification in conifers on the one hand and numerous examples of local adaptation in conifers on the other hand. We propose that reduced levels of nucleotide mutation in large and long-lived conifer trees, coupled with large effective population size, were the main factors leading to slow substitution rates but retention of beneficial mutations.

  3. Gender differences in co-occurrence of depressive and anger symptoms among adolescents in five Nordic countries.

    PubMed

    Asgeirsdottir, Bryndis Bjork; Sigfusdottir, Inga Dora

    2015-03-01

    The aim of this study was to carry out a comparative examination on gender differences in depressive and anger symptoms and their co-occurrence, using comparative self-report survey data from 16-19-year-old students in five Nordic countries. In total, 8038 adolescents participated in the study, 4183 females (52%) and 3855 males (48%) with an average age of 17.1 years. Analysis of Covariance (ANCOVA) was used to test for gender differences in symptoms for the sample as a whole and also for each country. Furthermore, partial bivariate correlation was carried out and followed up by ANCOVA to test for gender differences in the co-occurrence of depressive and anger symptoms in the five countries. The results indicated that, on average, adolescent females reported higher levels of depressive symptoms than males in all the countries under study and higher levels of anger symptoms in four out of five countries. The relationship between depressive and anger symptoms turned out to be stronger for females than males for all the countries under study, demonstrating higher co-occurrence of depressive and anger symptoms on average among females than males. The findings underline the need for attending to both depressive and anger symptoms among adolescents when designing mental health interventions and treatments as co-occurrence of both types of symptoms is common, particularly among females. © 2014 the Nordic Societies of Public Health.

  4. Atmospheric circulation and sounding-derived parameters associated with thunderstorm occurrence in Central Europe

    NASA Astrophysics Data System (ADS)

    Kolendowicz, Leszek; Taszarek, Mateusz; Czernecki, Bartosz

    2017-07-01

    The main objective of this study is to examine the influence of atmospheric circulation patterns and sounding-derived parameters on thunderstorm occurrence in Central Europe. Thunderstorm activity tends to increase as one moves from the north to the south of the research area. Maximal thunderstorm occurrence is observed in the summer months, while between October and March such activity is much lower. Thunderstorms are also more frequent in spring than in autumn. In the warm season, the occurrence of thunderstorm is associated with the presence of a trough associated with a low located over the North Sea and Scandinavia. In the cold season, the synoptic pattern indicates a strong zonal flow from the west with significantly higher horizontal pressure gradient compared to the warm season. Thunderstorms are more likely to form when the boundary layer's mixing ratios are higher than 8 g kg- 1. Deep convection is also more likely to occur when the vertical temperature lapse rates (between 800 and 500 hPa pressure layers) exceed 6 °C km- 1. During the cold season, considerably higher lapse rates are needed to produce thunderstorms. The values obtained for the convective available potential energy indicate that at least 50 J kg- 1 is needed to produce a thunderstorm during wintertime and 125 J kg- 1 during summertime. Cold season thunderstorms are formed with a lower instability but with a more dynamic wind field having an average value of deep layer shear that exceeds 20 ms- 1. The best parameter to distinguish thunderstorm from non-thunderstorm days for both winter and summer months is a combination of the square root of the convective available potential energy multiplied by the deep layer shear.

  5. Difference in occurrence of heterotopic ossification according to prosthesis type in the cervical artificial disc replacement.

    PubMed

    Yi, Seong; Kim, Keung Nyun; Yang, Moon Sul; Yang, Joong Won; Kim, Hoon; Ha, Yoon; Yoon, Do Heum; Shin, Hyun Chul

    2010-07-15

    Retrospective study of the difference of heterotopic ossification (HO) occurrence according to 3 different types of prosthesis. This study was designed to investigate the difference of HO occurrence according to different type of prosthesis. HO is defined as formation of the bone outside the skeletal system. Reported HO occurrence rate in cervical artificial disc replacement (ADR) was unexpectedly high and varied. But the influencing factors of HO in cervical ADR have not been elucidated well. The prosthesis-related factors for making difference of HO occurrence were investigated in this study. A total of 170 patients undergoing cervical arthroplasty with the Bryan cervical disc prosthesis (Medtroic Sofamor Danek, Memphis, TN), Mobi-C disc prosthesis (LDR Medical, Troyes, France), and ProDisc-C (Synthes, Inc., West Chester, PA) were included. Cervical lateral radiographs obtained before and after surgery were used to identify HO. Occurrence rate, occurrence-free period, location, and grade of HOs were investigated according to the different prosthesis. Each prosthesis group included patients as follows: Bryan disc, 81 patients; Mobi-C, 61 patients; and ProDisc-C, 28 patients. Overall HO rate was 40.6% (69 of 170 patients). Each HO occurrence rate by prosthesis was as follows: the Bryan disc group, 21.0%; Mobi-C group, 52.5%; and the ProDisc-C group, 71.4%. In the survival analysis, all patients showed 27.1 +/- 3.7 months as the median survival. The Bryan disc group showed statistically longer survival (48.4 +/- 7.4 months) than the other groups. Occurrence of HO is an inevitable postoperative complication after cervical ADR. The occurrence rate of HO was higher than our expectation. Moreover, definite differences in occurrence rate according to the prosthesis type were identified by this study.

  6. The evaluation of a rake method to quantify submersed vegetation in the Upper Mississippi River

    USGS Publications Warehouse

    Yin, Yao; Kreiling, Rebecca M.

    2011-01-01

    A long-handled, double-headed garden rake was used to collect submersed aquatic vegetation (SAV) and compared to in-boat visual inspection to record species presence at 67 individual sites. Six rake subsamples were taken at each site and a rake density rating was given to each species collected in the subsamples. Presence at the site, frequency of occurrence in the six rake samples, and additive density rating (the sum of the six rake density ratings) were quantified for each species at each site. The validity of the indices was tested against biomass data collected by clipping all remaining vegetation from the 67 sites. In the turbid water of the Mississippi River, visual inspection of SAV from boats was ineffective with only 27% of the species detected, while raking retrieved on average 70% of the total number of submersed species in the 67 sites. Presence of species at individual sites was correlated with biomass from Stuckenia pectinata, while frequency of occurrence and additive density rating were correlated with biomass for species with greater than 21 g of total biomass from all sites. The efficiency of the rake to collect biomass varied among species; only 18% of total biomass was captured via raking the site six times. Additive density rating as an index of abundance can be used to detect temporal changes in the same water body; however, cross-species comparison is not encouraged unless the efficiency of the rake has been determined for each species being compared.

  7. Climatic factors and community - associated methicillin-resistant Staphylococcus aureus skin and soft-tissue infections - a time-series analysis study.

    PubMed

    Sahoo, Krushna Chandra; Sahoo, Soumyakanta; Marrone, Gaetano; Pathak, Ashish; Lundborg, Cecilia Stålsby; Tamhankar, Ashok J

    2014-08-29

    Skin and soft tissue infections caused by Staphylococcus aureus (SA-SSTIs) including methicillin-resistant Staphylococcus aureus (MRSA) have experienced a significant surge all over the world. Changing climatic factors are affecting the global burden of dermatological infections and there is a lack of information on the association between climatic factors and MRSA infections. Therefore, association of temperature and relative humidity (RH) with occurrence of SA-SSTIs (n = 387) and also MRSA (n = 251) was monitored for 18 months in the outpatient clinic at a tertiary care hospital located in Bhubaneswar, Odisha, India. The Kirby-Bauer disk diffusion method was used for antibiotic susceptibility testing. Time-series analysis was used to investigate the potential association of climatic factors (weekly averages of maximum temperature, minimum temperature and RH) with weekly incidence of SA-SSTIs and MRSA infections. The analysis showed that a combination of weekly average maximum temperature above 33 °C coinciding with weekly average RH ranging between 55% and 78%, is most favorable for the occurrence of SA-SSTIs and MRSA and within these parameters, each unit increase in occurrence of MRSA was associated with increase in weekly average maximum temperature of 1.7 °C (p = 0.044) and weekly average RH increase of 10% (p = 0.097).

  8. [Oncomelania hupensis snail distribution in working areas of Yangtze River hydrologic agencies located in middle and lower reaches of Yangtze River in 2016].

    PubMed

    Min, Xu; Suo-Xin, Huang; Zheng-Yuan, Zhao; Ben-Jiao, Hu; Jun, Fu; Si-Min, Dai; Li-Hong, Wen

    2016-10-13

    To understand the Oncomelania hupensis snail distribution in the working areas of Yangtze River hydrologic agencies located in the middle and lower reaches of the Yangtze River in 2016, so as to provide the evidence for assessing the risk of schistosome infection of hydrological workers and establishing the control strategies. The suspicious environments with O. hupensis snails in the above working areas were selected as study areas, and the snail situation was surveyed by the system sampling method combined with the environmental sampling method. The survey data were collected and analyzed statistically. Totally 19 working areas from 17 hydrological agencies were selected as the investigation sites, among which, 10 working areas from 9 agencies were found with O. hupensis snail distribution. The constituent ratio of the areas with snails reached to 38.81% of the investigation areas, the occurrence rate of frames with snails was 3.08%, and the average density of living snails was 0.07 /0.1 m 2 . By comparison, the average density of living snails and occurrence rate of frames with snails in hydrological agencies under the jurisdiction of the Middle Reaches Administrative Bureau were the most serious among three administrative bureaus of the Yangtze River Water Resources Commission. There are various degrees of O. hupensis breeding in the working areas of hydrological agencies located in the middle and lower reaches of the Yangtze River, and the hydrological workers are facing with the risk of schistosome infection.

  9. A study of multi-GNSS ionospheric scintillation and cycle-slip over Hong Kong region for moderate solar flux conditions

    NASA Astrophysics Data System (ADS)

    Luo, Xiaomin; Liu, Zhizhao; Lou, Yidong; Gu, Shengfeng; Chen, Biyan

    2017-09-01

    This study presents the characteristics of Multiple Global Navigation Satellite System (Multi-GNSS) ionospheric scintillation and cycle-slip occurrence through the analysis of Multi-GNSS data collected by a newly installed receiver located at Sha Tin of Hong Kong from 6 October 2015 to 31 December 2016. This period of time was under a moderate solar activity condition with average sunspot number and F10.7 as 44 and 92, respectively. Considering the frequent occurrence of loss of lock in satellites measurements in the presence of ionospheric scintillation, a rate of geometry-free (ROGF) combination is proposed to take the time gap size between two data arcs into account in the cycle-slip detection. The results show that most ionospheric scintillation events and cycle-slips are observed from 20:00 LT to 0:00 LT. Under the strong scintillation (S4 > 0.6) conditions, it is found that the time series of wide-land (WL) ambiguity NWL and ROGF vary significantly and their range can reach more than 50 cycles and 0.1 m/s, respectively. However, the variations of the NWL and ROGF are generally small under weak scintillation (0.2 < S4 ≤ 0.6) or non-scintillation (S4 ≤ 0.2) conditions. A strong correlation of scintillation and cycle-slip occurrence is also verified by the daily and spatial statistics results. In addition, it is found that on average every 1000 strong scintillation events can result in 200, 124, and 171 cycle-slip occurrences in GPS, GLONASS, and BDS, respectively, whereas these values are 7, 12, and 12 per 1000 under weak scintillation conditions. This study suggests that cautions be taken when GNSS measurements are contaminated by the strong ionospheric scintillation in GNSS applications such as real-time kinematic (RTK) and precise point positioning (PPP).

  10. Occurrence of amyotrophic lateral sclerosis among Gulf War veterans.

    PubMed

    Horner, R D; Kamins, K G; Feussner, J R; Grambow, S C; Hoff-Lindquist, J; Harati, Y; Mitsumoto, H; Pascuzzi, R; Spencer, P S; Tim, R; Howard, D; Smith, T C; Ryan, M A K; Coffman, C J; Kasarskis, E J

    2003-09-23

    In response to Gulf War veterans' concerns of high rates of ALS, this investigation sought to determine if Gulf War veterans have an elevated rate of ALS. A nationwide epidemiologic case ascertainment study design was used to ascertain all occurrences of ALS for the 10-year period since August 1990 among active duty military and mobilized Reserves, including National Guard, who served during the Gulf War (August 2, 1990, through July 31, 1991). The diagnosis of ALS was confirmed by medical record review. Risk was assessed by the age-adjusted, average, annual 10-year cumulative incidence rate. Among approximately 2.5 million eligible military personnel, 107 confirmed cases of ALS were identified for an overall occurrence of 0.43 per 100,000 persons per year. A significant elevated risk of ALS occurred among all deployed personnel (RR = 1.92; 95% CL = 1.29, 2.84), deployed active duty military (RR = 2.15, 95% CL = 1.38, 3.36), deployed Air Force (RR = 2.68, 95% CL = 1.24, 5.78), and deployed Army (RR = 2.04; 95% CL = 1.10, 3.77) personnel. Elevated, but nonsignificant, risks were observed for deployed Reserves and National Guard (RR = 2.50; 95% CL = 0.88, 7.07), deployed Navy (RR = 1.48, 95% CL = 0.62, 3.57), and deployed Marine Corps (RR = 1.13; 95% CL = 0.27, 4.79) personnel. Overall, the attributable risk associated with deployment was 18% (95% CL = 4.9%, 29.4%). Military personnel who were deployed to the Gulf Region during the Gulf War period experienced a greater post-war risk of ALS than those who were not deployed to the Gulf.

  11. Source locations for impulsive electric signals seen in the night ionosphere of Venus

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Von Dornum, M.; Scarf, F. L.

    1989-01-01

    A mapping of the rate of occurrence of impulsive VLF noise bursts in Venus' dark low altitude ionosphere, which increases rapidly with decreasing altitude, as a function of latitude and longitude indicates enhanced occurrence rates over Atla. In a 30-sec observing period, there are impulsive signals 70 percent of the time at 160 km in the region of maximum occurrence; the occurrence rates, moreover, increase with decreasing latitude, so that the equatorial rate is of the order of 1.6 times that at 30 deg latitude. These phenomena are in keeping with lightning-generated wave sources.

  12. Limit on slip rate and timing of recent seismic ground-ruptures on the Jinghong fault, SE of the eastern Himalayan syntaxis

    NASA Astrophysics Data System (ADS)

    Shi, Xuhua; Weldon, Ray; Liu-Zeng, Jing; Wang, Yu; Weldon, Elise; Sieh, Kerry; Li, Zhigang; Zhang, Jinyu; Yao, Wenqian; Li, Zhanfei

    2018-06-01

    Quantifying slip rates and earthquake occurrence of active faults on the Shan Plateau, southeast of the eastern Himalayan syntaxis, is critical to assessing the seismic hazard and understanding the kinematics and geodynamics of this region. Most previous estimates of slip rates are averaged over either many millions of years using offset geological markers or decades using GPS. Well-constrained millennial slip rates of these faults remain sparse and constraints on recurrence rates of damaging earthquakes exist only for a few faults. Here we investigate the millennial slip rate and timing of recent earthquakes on the Jinghong fault, one of the geomorphically most significant sinistral-slip faults on the central Shan Plateau. We map and reconstruct fault offset (18 ± 5 m) of alluvial fan features at Manpa on the central Jinghong fault, using a 0.1 m-resolution digital surface model obtained from an unmanned aerial vehicle survey. We establish a slip rate, ≤2.5 ± 0.7 mm/yr over the past 7000 years, using pit-exposed stratigraphy. This millennial slip rate is consistent with rates averaged over both decadal and million-year timescales. Excavations at three sites near the town of Gelanghe on the northeastern Jinghong fault demonstrate 1) that the last seismic ground-rupture occurred between 482 and 889 cal yr BP, most likely in the narrower window 824-767 cal yr BP, if the lack of large earthquakes in the historical earthquake record is reliable, and 2) that multiple fault ruptures have occurred since 3618 cal yr BP. Combining this finding with a lack of large earthquakes in the 800-year-long Chinese historic record in this region, we suggest an average recurrence interval of seismic ground-ruptures on the order of 1000 years. This recurrence interval is consistent with the slip rate of the Jinghong fault and the size and earthquake frequency on other sinistral faults on the Shan Plateau.

  13. Estimation of Delta Wave by Mutual Information of Heartbeat During Sleep

    NASA Astrophysics Data System (ADS)

    Kurihara, Yosuke; Watanabe, Kajiro; Kobayashi, Kazuyuki; Tanaka, Hiroshi

    The quality of sleep is evaluated based on the sleep stages judged by R-K method or the manual of American Academy of Sleep Medicine. The brainwaves, eye movements, and chin EMG of sleeping subjects are used for the judgment. These methods above, however, require some electrodes to be attached to the head and the face to obtain the brainwaves, eye movements, and chin EMG, thus making the measurements troublesome to be held on a daily basis. If non-invasive measurements of brainwaves, eye movements, and chin EMG are feasible, or their equivalent data can be estimated through other bio-signals, the monitoring of the quality of daily sleeps, which influences the health condition, will be easy. In this paper, we discuss the appearance rate of delta wave occurrences, which is deeply related with the depth of sleep, can be estimated based on the average amount of mutual information calculated by pulse wave signals and body movements measured non-invasively by the pneumatic method. As a result, the root mean square error between the appearance rate of delta wave occurrences measured with a polysomnography and the estimated delta pulse was 14.93%.

  14. Statistics of co-occurring keywords in confined text messages on Twitter

    NASA Astrophysics Data System (ADS)

    Mathiesen, J.; Angheluta, L.; Jensen, M. H.

    2014-09-01

    Online social media such as the micro-blogging site Twitter has become a rich source of real-time data on online human behaviors. Here we analyze the occurrence and co-occurrence frequency of keywords in user posts on Twitter. From the occurrence rate of major international brand names, we provide examples of predictions of brand-user behaviors. From the co-occurrence rates, we further analyze the user-perceived relationships between international brand names and construct the corresponding relationship networks. In general the user activity on Twitter is highly intermittent and we show that the occurrence rate of brand names forms a highly correlated time signal.

  15. Correlation between femoral offset loss and dynamic hip screw cut-out complications after pertrochanteric fractures: a case-control study.

    PubMed

    Boukebous, Baptiste; Guillon, Pascal; Vandenbussche, Eric; Rousseau, Marc Antoine

    2018-04-27

    Screw-plates disassembly incidence after pertrochanteric fracture (PF) amounts to 1 and 16% among the elderly population. The main occurrence is early cervical screw cut-out. The population at highest risk of disassembly remains difficult to identify. The correlation between femoral offset loss and disassembly occurrence has never been surveyed. A radiological prognosis score for screw plate disassembly was defined to reflect trochanteric impaction (TI); it was based on a femoral offset ratio. Our single-centre retrospective case-control study surveyed patients suffering from Dynamic Hip Screw (DHS, Synthes ® ) disassembly following osteosynthesis of non-pathological osteoporotic PF between 2004 and 2014. All cases were categorised by age and gender and paired to three patients in the control group. The primary endpoint was TI measurement, corresponding to offset loss on the operated hip compared to healthy hip offset and expressed as a percentage. The measurement was done on an immediate postoperative X-ray. The secondary endpoints were tip apex distance (TAD) measurement, Ender and AO classifications, as well as postoperative weight-bearing prescription. Twenty-three cases and 69 controls were surveyed. The case group's average age was 87; 70% of the cases were women. The main disassembly occurrence delay was after 27 days. Average TI was 26% within the patients global group and 12% within the control group (p < 10 -5 ). Over a 21% impaction percentage, disassembly occurrence represents a greater risk: OR = 21.95% CI [5.4-104.3], p < 10 -5 . Ender 3 type fractures were the most frequent indication for surgery within the case group. Average TAD was 20 mm within the case group, and 17 mm within the control group (p = 0.03). The weight-bearing prescription rate was 52% within the control group and 21% within the case group (p = 0.014). 14.5% of the control group had a TI > 21%. Using the offset ratio tool, TI measurement was associated with a greater risk of DHS disassembly when it was higher than 21%. The exclusive use of a DHS device does not seem optimal for a TI > 21%. Weight-bearing may be prescribed for all the patients with a TI < 21%, provided good implant positioning is secured.

  16. Potential breeding distributions of U.S. birds predicted with both short-term variability and long-term average climate data

    Treesearch

    Brooke L. Bateman; Anna M. Pidgeon; Volker C. Radeloff; Curtis H. Flather; Jeremy VanDerWal; H. Resit Akcakaya; Wayne E. Thogmartin; Thomas P. Albright; Stephen J. Vavrus; Patricia J. Heglund

    2016-01-01

    Climate conditions, such as temperature or precipitation, averaged over several decades strongly affect species distributions, as evidenced by experimental results and a plethora of models demonstrating statistical relations between species occurrences and long-term climate averages. However, long-term averages can conceal climate changes that have occurred in...

  17. Interaction of light and gravitropism with nutation of hypocotyls of Arabidopsis thaliana seedlings

    NASA Technical Reports Server (NTRS)

    Orbovic, V.; Poff, K. L.

    1997-01-01

    Etiolated seedlings of Arabidopsis thaliana nutated under conditions of physiological darkness while about ten percent of monitored individuals exhibited regular elliptical nutation, circumnutation. Pre-irradiation with red light prevented occurrence of circumnutation without having an effect on the average rate of the nutational movement. Phototropic response of seedlings to unilateral blue light appeared to be superimposed over nutation. Throughout gravitropism, some seedlings continued to exhibit nutation suggesting that these two processes are independently controlled. Based on these results, we suggest that nutation in Arabidopsis probably is not controlled by the mechanism predicted by the theory of gravitropic overshoots.

  18. Crash test ratings and real-world frontal crash outcomes: a CIREN study.

    PubMed

    Ryb, Gabriel E; Burch, Cynthia; Kerns, Timothy; Dischinger, Patricia C; Ho, Shiu

    2010-05-01

    To establish whether the Insurance Institute for Highway Safety (IIHS) offset crash test ratings are linked to different mortality rates in real world frontal crashes. The study used Crash Injury Research Engineering Network drivers of age older than 15 years who were involved in frontal crashes. The Crash Injury Research Engineering Network is a convenience sample of persons injured in crashes with at least one Abbreviated Injury Scale score of 3+ injury or two Abbreviated Injury Scale score of 2+ injuries who were either treated at a Level I trauma center or died. Cases were grouped by IIHS crash test ratings (i.e., good, acceptable, marginal, poor, and not rated). Those rated marginal were excluded because of their small numbers. Mortality rates experienced by these ratings-based groups were compared using the Mantel-Haenszel chi test. Multiple logistic regression models were built to adjust for confounders (i.e., occupant, vehicular, and crash factors). A total of 1,226 cases were distributed within not rated (59%), poor (12%), average (16%), and good (14%) categories. Those rated good and average experienced a lower unadjusted mortality rate. After adjustment by confounders, those in vehicles rated good experienced a lower risk of death (adjusted OR 0.38 [0.16-0.90]) than those in vehicles rated poor. There was no significant effect for "acceptable" rating. Other factors influencing the occurrence of death were age, DeltaV >or=70 km/h, high body mass index, and lack of restraint use. After adjusting for occupant, vehicular, and crash factors, drivers of vehicles rated good by the IIHS experienced a lower risk of death in frontal crashes.

  19. The Occurrence Rate and Diameter of Arteries Traveling Near the Mandible and an Assessment of the Relative Hemorrhage Risk in Implant Surgery.

    PubMed

    Katsumi, Yuji; Takagi, Ritsuo; Ohshima, Hayato

    2016-10-01

    Bleeding in the floor of the mouth during implant surgery is attributed to arterial injuries in the sublingual space. This study aimed to assess the relative hemorrhage risk during implant surgery. We investigated the occurrence rate and diameter of submental and sublingual arteries with special reference to their relationship with the course patterns of these arteries using 26 human cadavers. Three types of arteries were distinguished: main duct (MD), mucoperiosteal branches (MB), and cortical branches (CB). The occurrence rate of MB and CB was significantly high at the central incisor region in the upper part of the mylohyoid muscle, whereas the diameter of the MB and CB was significantly smaller than the occurrence rate of MD at the incisor regions. The occurrence rate of MD in the submental artery was significantly higher at the lateral incisor, canine, and premolar regions in the lower parts, whereas the occurrence rate of MD was significantly lower at the second and third molars in the upper parts. The susceptibility of the submental artery to injury is suggested at the incisors, canine, premolars, and first molar regions during implant surgery. © 2015 Wiley Periodicals, Inc.

  20. Distal biceps tendon rupture reconstruction using muscle-splitting double-incision approach

    PubMed Central

    Tarallo, Luigi; Mugnai, Raffaele; Zambianchi, Francesco; Adani, Roberto; Catani, Fabio

    2014-01-01

    AIM: To evaluate the clinical and functional results after repair of distal biceps tendon tears, following the Morrey’s modified double-incision approach. METHODS: We retrospectively reviewed 47 patients with distal rupture of biceps brachii treated between 2003 and 2012 in our Orthopedic Department with muscle-splitting double-incision technique. Outcome measures included the Mayo elbow performance, the DASH questionnaire, patient’s satisfaction, elbow and forearm motion, grip strength and complications occurrence. RESULTS: At an average 18 mo follow-up (range, 7 mo-10 years) the average Mayo elbow performance and DASH score were respectively 97.2 and 4.8. The elbow flexion range was 94%, extension was -2°, supination was 93% and pronation 96% compared with the uninjured limb. The mean grip strength, expressed as percentage of respective contralateral limb, was 83%. The average patient satisfaction rating on a Likert scale (from 0 to 10) was 9.4. The following complications were observed: 3 cases of heterotopic ossification (6.4%), one (2.1%) re-rupture of the tendon at the site of reattachment and 2 cases (4.3%) of posterior interosseous nerve palsy. No complication required further surgical treatment. CONCLUSION: This technique allows an anatomic reattachment of distal biceps tendon at the radial tuberosity providing full functional recovery with low complication rate. PMID:25133147

  1. Implications of depleted flux tubes in the Jovian magnetosphere

    NASA Astrophysics Data System (ADS)

    Russell, C. T.; Kivelson, M. G.; Kurth, W. S.; Gurnett, D. A.

    2000-10-01

    A rare but persistent phenomenon in the jovian magnetosphere is the occurrence of apparently depleted flux tubes, whose magnetic pressures are significantly above ambient levels. These flux tubes occur about 0.25% of the observing time in the region of the Io torus in the Galileo high resolution data. The importance of these tubes is that they can return to the inner magnetosphere the magnetic flux that has been convected radially outward with the iogenic plasma to the tail. The paucity of these tubes is consistent with the expected flux return rates if the tubes are moving inward at an average rate of about 5-10 km/s in the torus. Depleted flux tubes have yet to be observed inside of the Io orbit where the plasma beta is lower than in the hot torus. Estimates of the plasma density outside the tube from plasma wave measurements enable the average perpendicular temperature to be obtained from the magnetic field change. Extrapolating this temperature back to Io, we obtain an average ion temperature of approximately 60 eV. These values are generally consistent with earlier Voyager observations but on the low side of their range of uncertainty, and agree quite well with contemporaneous Galileo measurements where these are available.

  2. Implications of Depleted flux Tubes in the Jovian Magnetosphere

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Kivelson, M. G.; Kurth, W. S.; Gurnett, D. A.

    2000-01-01

    A rare but persistent phenomenon in the jovian magnetosphere is the occurrence of apparently depleted flux tubes, whose magnetic pressures are significantly above ambient levels. These flux tubes occur about 0.25% of the observing time in the region of the Io torus in the Galileo high resolution data. The importance of these tubes is that they can return to the inner magnetosphere the magnetic flux that has been convected radially outward with the iogenic plasma to the tail. The paucity of these tubes is consistent with the expected flux return rates if the tubes are moving inward at an average rate of about 5-10 km/s in the torus. Depleted flux tubes have yet to be observed inside of the lo orbit where the plasma beta is lower than in the hot torus. Estimates of the plasma density outside the tube from plasma wave measurements enable the average perpendicular temperature to be obtained from the magnetic field change. Extrapolating this temperature back to lo, we obtain an average ion temperature of approximately 60 eV. These values are generally consistent with earlier Voyager observations but on the low side of their range of uncertainty, and agree quite well with contemporaneous Galileo measurements where these are available.

  3. Climatic Factors and Community — Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft-Tissue Infections — A Time-Series Analysis Study

    PubMed Central

    Sahoo, Krushna Chandra; Sahoo, Soumyakanta; Marrone, Gaetano; Pathak, Ashish; Lundborg, Cecilia Stålsby; Tamhankar, Ashok J.

    2014-01-01

    Skin and soft tissue infections caused by Staphylococcus aureus (SA-SSTIs) including methicillin-resistant Staphylococcus aureus (MRSA) have experienced a significant surge all over the world. Changing climatic factors are affecting the global burden of dermatological infections and there is a lack of information on the association between climatic factors and MRSA infections. Therefore, association of temperature and relative humidity (RH) with occurrence of SA-SSTIs (n = 387) and also MRSA (n = 251) was monitored for 18 months in the outpatient clinic at a tertiary care hospital located in Bhubaneswar, Odisha, India. The Kirby-Bauer disk diffusion method was used for antibiotic susceptibility testing. Time-series analysis was used to investigate the potential association of climatic factors (weekly averages of maximum temperature, minimum temperature and RH) with weekly incidence of SA-SSTIs and MRSA infections. The analysis showed that a combination of weekly average maximum temperature above 33 °C coinciding with weekly average RH ranging between 55% and 78%, is most favorable for the occurrence of SA-SSTIs and MRSA and within these parameters, each unit increase in occurrence of MRSA was associated with increase in weekly average maximum temperature of 1.7 °C (p = 0.044) and weekly average RH increase of 10% (p = 0.097). PMID:25177823

  4. Experimental investigation of false positive errors in auditory species occurrence surveys

    USGS Publications Warehouse

    Miller, David A.W.; Weir, Linda A.; McClintock, Brett T.; Grant, Evan H. Campbell; Bailey, Larissa L.; Simons, Theodore R.

    2012-01-01

    False positive errors are a significant component of many ecological data sets, which in combination with false negative errors, can lead to severe biases in conclusions about ecological systems. We present results of a field experiment where observers recorded observations for known combinations of electronically broadcast calling anurans under conditions mimicking field surveys to determine species occurrence. Our objectives were to characterize false positive error probabilities for auditory methods based on a large number of observers, to determine if targeted instruction could be used to reduce false positive error rates, and to establish useful predictors of among-observer and among-species differences in error rates. We recruited 31 observers, ranging in abilities from novice to expert, that recorded detections for 12 species during 180 calling trials (66,960 total observations). All observers made multiple false positive errors and on average 8.1% of recorded detections in the experiment were false positive errors. Additional instruction had only minor effects on error rates. After instruction, false positive error probabilities decreased by 16% for treatment individuals compared to controls with broad confidence interval overlap of 0 (95% CI: -46 to 30%). This coincided with an increase in false negative errors due to the treatment (26%; -3 to 61%). Differences among observers in false positive and in false negative error rates were best predicted by scores from an online test and a self-assessment of observer ability completed prior to the field experiment. In contrast, years of experience conducting call surveys was a weak predictor of error rates. False positive errors were also more common for species that were played more frequently, but were not related to the dominant spectral frequency of the call. Our results corroborate other work that demonstrates false positives are a significant component of species occurrence data collected by auditory methods. Instructing observers to only report detections they are completely certain are correct is not sufficient to eliminate errors. As a result, analytical methods that account for false positive errors will be needed, and independent testing of observer ability is a useful predictor for among-observer variation in observation error rates.

  5. Contamination levels of human pharmaceutical compounds in French surface and drinking water.

    PubMed

    Mompelat, S; Thomas, O; Le Bot, B

    2011-10-01

    The occurrence of 20 human pharmaceutical compounds and metabolites from 10 representative therapeutic classes was analysed from resource and drinking water in two catchment basins located in north-west France. 98 samples were analysed from 63 stations (surface water and drinking water produced from surface water). Of the 20 human pharmaceutical compounds selected, 16 were quantified in both the surface water and drinking water, with 22% of the values above the limit of quantification for surface water and 14% for drinking water). Psychostimulants, non-steroidal anti-inflammatory drugs, iodinated contrast media and anxiolytic drugs were the main therapeutic classes of human pharmaceutical compounds detected in the surface water and drinking water. The results for surface water were close to results from previous studies in spite of differences in prescription rates of human pharmaceutical compounds in different countries. The removal rate of human pharmaceutical compounds at 11 water treatment units was also determined. Only caffeine proved to be resistant to drinking water treatment processes (with a minimum rate of 5%). Other human pharmaceutical compounds seemed to be removed more efficiently (average elimination rate of over 50%) by adsorption onto activated carbon and oxidation/disinfection with ozone or chlorine (not taking account of the disinfection by-products). These results add to the increasing evidence of the occurrence of human pharmaceutical compounds in drinking water that may represent a threat to human beings exposed to a cocktail of human pharmaceutical compounds and related metabolites and by-products in drinking water.

  6. Application of passive sampling in assessing the occurrence and risk of antibiotics and endocrine disrupting chemicals in the Yangtze Estuary, China.

    PubMed

    Shi, X; Zhou, J L; Zhao, H; Hou, L; Yang, Y

    2014-09-01

    Polar organic chemical integrative sampler (POCIS) was used in assessing the occurrence and risk of 12 widely used antibiotics and 5 most potent endocrine disrupting chemicals (EDCs) in the Yangtze Estuary, China. During laboratory validation, the kinetics of pollutant uptake by POCIS were linear, and the sampling rates of most compounds were raised by flow rate and salinity, reaching the highest values at salinity 14‰. The sampling rates varied with the target compounds with the EDCs showing the highest values (overall average=0.123Ld(-1)), followed by chloramphenicols (0.100Ld(-1)), macrolides (0.089Ld(-1)), and finally sulfonamides (0.056Ld(-1)). Validation in the Yangtze Estuary in 2013 showed that the field sampling rates were significantly greater for all compounds except bisphenol A, in comparison to laboratory results, and high-frequency spot sampling is critical for fully validating the passive sampler. The field studies show that antibiotics were widely detected in the Yangtze Estuary, with concentrations varying from below quantification to 1613ngL(-1), suggesting their widespread use and persistence in estuarine waters. The dominating pollutants in July were sulfonamides with a total concentration of 258ngL(-1) and in October were macrolides with a total concentration of 350ngL(-1). The calculation of risk quotient suggested that sulfapyridine, sulfaquinoxaline and erythromycin-H2O may have caused medium damage to sensitive organisms such as fish. Copyright © 2014. Published by Elsevier Ltd.

  7. Silent Atrial Fibrillation in Elderly Pacemaker Users: A Randomized Trial Using Home Monitoring.

    PubMed

    Lima, Ceb; Martinelli, M; Peixoto, G L; Siqueira, S F; Wajngarten, Maurício; Silva, Rodrigo Tavares; Costa, Roberto; Filho, Roberto; Ramires, José Antônio Franchini

    2016-05-01

    Pacemaker with remote monitoring (PRM) may be useful for silent atrial fibrillation (AF) detection. The aims of this study were to evaluate the incidence of silent AF, the role of PRM, and to determine predictors of silent AF occurrence. Three hundred elderly patients with permanent pacemaker (PPM) were randomly assigned to the remote group (RG) or control group (CG). All patients received PPM with remote monitoring capabilities. Primary end point was AF occurrence rate and the secondary end points were time to AF detection and number of days with AF. During the average follow-up of 15.7±7.7 months, AF episodes were detected in 21.6% (RG = 24% vs CG = 19.3%, P = 0.36]. There was no difference in the time to detect the first AF episode. However, the median time to detect AF recurrence in the RG was lower than that in the CG (54 days vs 100 days, P = 0.004). The average number of days with AF was 16.0 and 51.2 in the RG and CG, respectively (P = 0.028). Predictors of silent AF were left atrial diameter (odds ratio [OR] 1.2; 95% CI = 1.1-1.3; P < 0.001) and diastolic dysfunction (OR 4.8; 95% CI = 1.6-14.0; P = 0.005). The incidence of silent AF is high in elderly patients with pacemaker; left atrial diameter and diastolic dysfunction were predictors of its occurrence. AF monitoring by means of pacemaker is a valuable tool for silent AF detection and continuous remote monitoring allows early AF recurrence detection and reduces the number of days with AF. © 2015 Wiley Periodicals, Inc.

  8. Chapter 30: Marbled Murrelet Populations of Washington — Marine Habitat Preferences and Variability of Occurrence

    Treesearch

    Steven M. Speich; Terrence R. Wahl

    1995-01-01

    Marbled Murrelets occur in Puget Sound marine habitats in relatively low numbers. The rates of occurrence of murrelets on censuses within marine habitats is generally low. Further analysis is required to determine if low occurrence rates are a general function of the movement of birds, or their consistent occurrence on particular censuses and not on others. Qualitative...

  9. Improving the Accuracy of Planet Occurrence Rates from Kepler Using Approximate Bayesian Computation

    NASA Astrophysics Data System (ADS)

    Hsu, Danley C.; Ford, Eric B.; Ragozzine, Darin; Morehead, Robert C.

    2018-05-01

    We present a new framework to characterize the occurrence rates of planet candidates identified by Kepler based on hierarchical Bayesian modeling, approximate Bayesian computing (ABC), and sequential importance sampling. For this study, we adopt a simple 2D grid in planet radius and orbital period as our model and apply our algorithm to estimate occurrence rates for Q1–Q16 planet candidates orbiting solar-type stars. We arrive at significantly increased planet occurrence rates for small planet candidates (R p < 1.25 R ⊕) at larger orbital periods (P > 80 day) compared to the rates estimated by the more common inverse detection efficiency method (IDEM). Our improved methodology estimates that the occurrence rate density of small planet candidates in the habitable zone of solar-type stars is {1.6}-0.5+1.2 per factor of 2 in planet radius and orbital period. Additionally, we observe a local minimum in the occurrence rate for strong planet candidates marginalized over orbital period between 1.5 and 2 R ⊕ that is consistent with previous studies. For future improvements, the forward modeling approach of ABC is ideally suited to incorporating multiple populations, such as planets, astrophysical false positives, and pipeline false alarms, to provide accurate planet occurrence rates and uncertainties. Furthermore, ABC provides a practical statistical framework for answering complex questions (e.g., frequency of different planetary architectures) and providing sound uncertainties, even in the face of complex selection effects, observational biases, and follow-up strategies. In summary, ABC offers a powerful tool for accurately characterizing a wide variety of astrophysical populations.

  10. Occurrence features of simultaneous H+- and He+-band EMIC emissions in the outer radiation belt

    NASA Astrophysics Data System (ADS)

    Fu, Song; He, Fengming; Gu, Xudong; Ni, Binbin; Xiang, Zheng; Liu, Jiang

    2018-04-01

    As an important loss mechanism of radiation belt electrons, electromagnetic ion cyclotron (EMIC) waves show up as three distinct frequency bands below the hydrogen (H+), helium (He+), and oxygen (O+) ion gyrofrequencies. Compared to O+-band EMIC waves, H+- and He+-band emissions generally occur more frequently and result in more efficient scattering removal of <∼5 MeV relativistic electrons. Therefore, knowledge about the occurrence of these two bands is important for understanding the evolution of the relativistic electron population. To evaluate the occurrence pattern and wave properties of H+- and He+-band EMIC waves when they occur concurrently, we investigate 64 events of multi-band EMIC emissions identified from high quality Van Allen Probes wave data. Our quantitative results demonstrate a strong occurrence dependence of the multi-band EMIC emissions on magnetic local time (MLT) and L-shell to mainly concentrate on the dayside region of L = ∼4-6. We also find that the average magnetic field amplitude of H+-band waves is larger than that of He+-band waves only when L < 4.5 and AE∗ < 300 nT, and He+-band emissions are more intense under all other conditions. In contrast to 5 events that have average H+-band amplitude over 2 nT, 19 events exhibit >2 nT He+-band amplitude, indicating that the He+-band waves can be more easily amplified than the H+-band waves under the same circumstances. For simultaneous occurrences of the two EMIC wave bands, their frequencies vary with L-shell and geomagnetic activity: the peak wave frequency of H+-band emissions varies between 0.25 and 0.8 fcp with the average between 0.25 and 0.6 fcp, while that of He+-band emissions varies between 0.03 and 0.23 fcp with the average between 0.05 and 0.15 fcp. These newly observed occurrence features of simultaneous H+- and He+-band EMIC emissions provide improved information to quantify the overall contribution of multi-band EMIC waves to the loss processes of radiation belt electrons.

  11. Workflow and intervention times of MR-guided focused ultrasound - Predicting the impact of new techniques.

    PubMed

    Loeve, Arjo J; Al-Issawi, Jumana; Fernandez-Gutiérrez, Fabiola; Langø, Thomas; Strehlow, Jan; Haase, Sabrina; Matzko, Matthias; Napoli, Alessandro; Melzer, Andreas; Dankelman, Jenny

    2016-04-01

    Magnetic resonance guided focused ultrasound surgery (MRgFUS) has become an attractive, non-invasive treatment for benign and malignant tumours, and offers specific benefits for poorly accessible locations in the liver. However, the presence of the ribcage and the occurrence of liver motion due to respiration limit the applicability MRgFUS. Several techniques are being developed to address these issues or to decrease treatment times in other ways. However, the potential benefit of such improvements has not been quantified. In this research, the detailed workflow of current MRgFUS procedures was determined qualitatively and quantitatively by using observation studies on uterine MRgFUS interventions, and the bottlenecks in MRgFUS were identified. A validated simulation model based on discrete events simulation was developed to quantitatively predict the effect of new technological developments on the intervention duration of MRgFUS on the liver. During the observation studies, the duration and occurrence frequencies of all actions and decisions in the MRgFUS workflow were registered, as were the occurrence frequencies of motion detections and intervention halts. The observation results show that current MRgFUS uterine interventions take on average 213min. Organ motion was detected on average 2.9 times per intervention, of which on average 1.0 actually caused a need for rework. Nevertheless, these motion occurrences and the actions required to continue after their detection consumed on average 11% and up to 29% of the total intervention duration. The simulation results suggest that, depending on the motion occurrence frequency, the addition of new technology to automate currently manual MRgFUS tasks and motion compensation could potentially reduce the intervention durations by 98.4% (from 256h 5min to 4h 4min) in the case of 90% motion occurrence, and with 24% (from 5h 19min to 4h 2min) in the case of no motion. In conclusion, new tools were developed to predict how intervention durations will be affected by future workflow changes and by the introduction of new technology. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Temporal and Spatial Patterns of Preferential Flow Occurrence in the Shale Hills Catchment: From the Hillslope to the Catchment Scales

    NASA Astrophysics Data System (ADS)

    Liu, H.; Lin, H.

    2013-12-01

    Understanding temporal and spatial patterns of preferential flow (PF) occurrence is important in revealing hillslope and catchment hydrologic and biogeochemical processes. Quantitative assessment of the frequency and control of PF occurrence in the field, however, has been limited, especially at the landscape scale of hillslope and catchment. By using 5.5-years' (2007-2012) real-time soil moisture at 10 sites response to 323 precipitation events, we tested the temporal consistency of PF occurrence at the hillslope scale in the forested Shale Hills Catchment; and by using 25 additional sites with at least 1-year data (2011-2012), we evaluated the spatial patterns of PF occurrence across the catchment. To explore the potential effects of PF occurrence on catchment hydrology, wavelet analysis was performed on the recorded time series of hydrological signals (i.e., precipitation, soil moisture, catchment discharge). Considerable temporal consistence was observed in both the frequency and the main controls of PF occurrence at the hillslope scale, which was attributed largely to the statistical stability of precipitation pattern over the monitoring period and the relatively stable subsurface preferential pathways. Preferential flow tended to occur more often in response to intense rainfall events, and favored the conditions at dry hilltop or wet valley floor sites. When upscaling to the entire catchment, topographic control on the PF occurrence was amplified remarkably, leading to the identification of a subsurface PF network in the catchment. Higher frequency of PF occurrence was observed at the valley floor (average 48%), hilltop (average 46%), and swales/hillslopes near the stream (average 40%), while the hillslopes in the eastern part of the catchment were least likely to experience PF (0-20%). No clear relationship, however, was observed between terrain attributes and PF occurrence, because the initiation and persistency of PF in this catchment was controlled jointly by complex interactions among landform units, soil types, initial soil moisture, precipitation features, and season. Through the wavelet method (coherence spectrum and phase differences), dual-pore filtering effects of soil system were proven, rendering it possible to further infer characteristic properties of the underlying hydrological processes in the subsurface. We found that preferential flow dominates the catchment discharge response at short-time periods (< 3 days), while the matrix flow may dominate the discharge response at the time scales of around 10-12 days. The temporal and spatial patterns of PF occurrence revealed in this study can help advance the modeling and prediction of complex PF dynamics in this and other similar landscapes.

  13. Occurrence of tetracycline-resistant fecal coliforms and their resistance genes in an urban river impacted by municipal wastewater treatment plant discharges.

    PubMed

    Zhang, Chong-Miao; Du, Cong; Xu, Huan; Miao, Yan-Hui; Cheng, Yan-Yan; Tang, Hao; Zhou, Jin-Hong; Wang, Xiao-Chang

    2015-01-01

    Antibiotic resistance of fecal coliforms in an urban river poses great threats to both human health and the environment. To investigate the occurrence and distribution of antibiotic resistant bacteria in an urban river, water samples were collected from the Chanhe River in Xi'an, China. After membrane filtration of water samples, the tetracycline resistance rate of fecal coliforms and their resistance genes were detected by plating and polymerase chain reaction (PCR), respectively. We found that fecal coliforms were generally resistant to tetracycline and saw average resistance rates of 44.7%. The genes tetA and tetB were widely detected, and their positive rate was 60%-100% and 40%-90%, respectively. We found few strains containing tetC, tetK, tetQ and tetX, and we did not identify any strains containing tetG, tetM or tetO. The prevalence of tetA and tetB over other genes indicated that the main mechanism for resistance to tetracycline is by changes to the efflux pump. Our analysis of the types and proportion of tetracycline resistance genes in the Chanhe River at locations upstream and downstream of the urban center suggests that the increased number of tetracycline-resistant fecal coliforms and spatial variation of tetracycline resistance genes diversity were related to municipal wastewater treatment plant discharge.

  14. The remarkable geographical pattern of gastric cancer mortality in Ecuador.

    PubMed

    Montero-Oleas, Nadia; Núñez-González, Solange; Simancas-Racines, Daniel

    2017-12-01

    This study was aimed to describe the gastric cancer mortality trend, and to analyze the spatial distribution of gastric cancer mortality in Ecuador, between 2004 and 2015. Data were collected from the National Institute of Statistics and Census (INEC) database. Crude gastric cancer mortality rates, standardized mortality ratios (SMRs) and indirect standardized mortality rates (ISMRs) were calculated per 100,000 persons. For time trend analysis, joinpoint regression was used. The annual percentage rate change (APC) and the average annual percent change (AAPC) was computed for each province. Spatial age-adjusted analysis was used to detect high risk clusters of gastric cancer mortality, from 2010 to 2015, using Kulldorff spatial scan statistics. In Ecuador, between 2004 and 2015, gastric cancer caused a total of 19,115 deaths: 10,679 in men and 8436 in women. When crude rates were analyzed, a significant decline was detected (AAPC: -1.8%; p<0.001). ISMR also decreased, but this change was not statistically significant (APC: -0.53%; p=0.36). From 2004 to 2007 and from 2008 to 2011 the province with the highest ISMR was Carchi; and, from 2012 to 2015, was Cotopaxi. The most likely high occurrence cluster included Bolívar, Los Ríos, Chimborazo, Tungurahua, and Cotopaxi provinces, with a relative risk of 1.34 (p<0.001). There is a substantial geographic variation in gastric cancer mortality rates among Ecuadorian provinces. The spatial analysis indicates the presence of high occurrence clusters throughout the Andes Mountains. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Monosynaptic EPSPs elicited by single interneurones and spindle afferents in trigeminal motoneurones of anaesthetized rats.

    PubMed Central

    Grimwood, P D; Appenteng, K; Curtis, J C

    1992-01-01

    1. Our aim has been to quantify the monosynaptic connections of trigeminal interneurones and spindle afferents onto jaw-elevator motoneurones as a step towards identifying common features in organization of monosynaptic inputs onto motoneurones. We have used the intracellular variant of the spike-triggered averaging method to examine the connections of single identified trigeminal interneurones and jaw-elevator muscle spindle afferents onto single jaw-elevator motoneurones. The interneurones examined lay in the region immediately caudal to the trigeminal motor nucleus. The experiments were performed on rats anaesthetized with pentobarbitone, paralysed and artificially ventilated. 2. Ten EPSPs and eight IPSPs were obtained from examining the connections of seventeen interneurones to thirty-six motoneurones, suggesting a functional connectivity of 50% for individual interneurones onto elevator motoneurones. Fourteen EPSPs were obtained from examining the connections of thirteen spindle afferents onto twenty-seven motoneurones, giving a functional connectivity of 52% for individual spindle afferents onto elevator motoneurones. The amplitudes of the EPSPs elicited by interneurones ranged from 7-48 microV (mean = 17, S.D. = 12.5, n = 10) and from 7 to 289 microV (mean = 64, S.D. = 76.0, n = 14) for the spindle-mediated EPSPs; the difference in the two means was not significant (P = 0.07). 3. However, the amplitude of averaged responses obtained by signal averaging methods are dependent on the assumption that the postsynaptic response occurs following every impulse in the presynaptic neurone. We therefore estimated the percentage of sweeps which contained EPSPs triggered by the presynaptic neurone under study. In essence the method used consisted of visual inspection of the individual sweeps comprising an average in order to assess the occurrence of EPSPs within six separate time windows, each of duration +/- 0.3 ms. Five windows were placed at randomly selected times on average and were used to provide an estimate of the frequency of occurrence of randomly triggered EPSPs. The sixth window was centred on the start of the averaged EPSP and the frequency of occurrence of randomly triggered EPSPs was subtracted from the frequency of occurrence of EPSPs in this window to produce an estimate of the incidence of EPSPs triggered by the presynaptic neurone under study. 4. Values of the incidence of occurrence of EPSPs triggered by the presynaptic neurones ranged from 4.3 to 92% for the fifteen averaged EPSPs which could be analysed in this manner (two elicited by interneurones and thirteen by spindle afferents).(ABSTRACT TRUNCATED AT 400 WORDS) PMID:1484366

  16. Correlation Analysis of Cocoa Consumption Data with Worldwide Incidence Rates of Testicular Cancer and Hypospadias

    PubMed Central

    Giannandrea, Fabrizio

    2009-01-01

    The underlying reasons for the increasing occurrence of male reproductive diseases (MRD) such as hypospadias, cryptorchidism, and testicular cancer (TC) over the last decades are still unknown. It has been hypothesized that the risk of MRD is determined in utero and that pregnancy dietary intake could also affect MRD risk in the offspring. Various studies in animals reported that cocoa and theobromine, the main stimulant of cocoa, exert toxic effects on the testis, inducing testicular atrophy and impaired sperm quality. A correlation analysis was conducted to examine the possible role of cocoa consumption on the occurrence of selected MRD during the prenatal and early life period of cases. The incidence rates between 1998–2002 of TC in 18 countries obtained from Cancer Incidence in Five Continents were correlated with the average per-capita consumption of cocoa (kg/capita/year) (FAOSTAT-Database) in these countries from 1965 to 1980, i.e. the period corresponding to the early life of TC cases. In order to test the above correlation in the case of hypospadias, the mean prevalence at birth in 20 countries (1999–2003) with average per-capita consumption of cocoa in these countries in the same period corresponding to pregnancy were used. The consumption of cocoa in the period 1965–80, was most closely correlated with the incidence of TC in young adults (r=0.859; p<0.001). An analogous significant correlation was also observed between early cocoa consumption and the prevalence rates of hypospadias in the period 1999–2003 (r=0.760; p<0.001). Although the ecological approach used in this study cannot provide an answer on the causal relationship between consumption of cocoa in early life and TC and hypospadias, the results are suggestive and indicate the need of further analytic studies to investigate the role of individual exposure to cocoa, particularly during the prenatal and in early life of the patients. PMID:19440400

  17. Correlation analysis of cocoa consumption data with worldwide incidence rates of testicular cancer and hypospadias.

    PubMed

    Giannandrea, Fabrizio

    2009-02-01

    The underlying reasons for the increasing occurrence of male reproductive diseases (MRD) such as hypospadias, cryptorchidism, and testicular cancer (TC) over the last decades are still unknown. It has been hypothesized that the risk of MRD is determined in utero and that pregnancy dietary intake could also affect MRD risk in the offspring. Various studies in animals reported that cocoa and theobromine, the main stimulant of cocoa, exert toxic effects on the testis, inducing testicular atrophy and impaired sperm quality. A correlation analysis was conducted to examine the possible role of cocoa consumption on the occurrence of selected MRD during the prenatal and early life period of cases. The incidence rates between 1998-2002 of TC in 18 countries obtained from Cancer Incidence in Five Continents were correlated with the average per-capita consumption of cocoa (kg/capita/year) (FAOSTAT-Database) in these countries from 1965 to 1980, i.e. the period corresponding to the early life of TC cases. In order to test the above correlation in the case of hypospadias, the mean prevalence at birth in 20 countries (1999-2003) with average per-capita consumption of cocoa in these countries in the same period corresponding to pregnancy were used. The consumption of cocoa in the period 1965-80, was most closely correlated with the incidence of TC in young adults (r=0.859; p<0.001). An analogous significant correlation was also observed between early cocoa consumption and the prevalence rates of hypospadias in the period 1999-2003 (r=0.760; p<0.001). Although the ecological approach used in this study cannot provide an answer on the causal relationship between consumption of cocoa in early life and TC and hypospadias, the results are suggestive and indicate the need of further analytic studies to investigate the role of individual exposure to cocoa, particularly during the prenatal and in early life of the patients.

  18. [X-ray characteristics of sacroiliac joint disorders and its clinical significance].

    PubMed

    Shi, Ning-Ning; Shen, Guo-Quan; He, Shui-Yong; Guo, Ru-bao

    2013-02-01

    To study the X-ray characteristics of sacroiliac joint disorders and its clinical significance,so as to provide clinical diagnosis basis for Tuina treatment of sacroiliac joint disorder. From July 2009 to March 2011,104 patients with sacroiliac joint disorder were reviewed,including 64 males and 40 females,ranging in age from 18 to 81 years, with an average of (45.39 +/- 1.30) years. The duration of the disease ranged from 1 to 144 months,with an average of (12.64 +/- 2.19) months. One hundred and four pelvic plain films and 97 lumbar spine lateral films of the patients with sacroiliac joint disorder were taken. On the lateral X-ray of lumbar,the sacral horizontal angles (lumbosacral angle) were measured; and on the X-ray of pelvis,the vertical distance of two side iliac crest (iliac crest difference), the distance from lateral border to medial margin of two hips (hip width),the clip angle between sacral spin connection and vertical axis were measured,and then the data were analyzed. The mean difference of iliac crest was (10.34+/-0.73) mm; the mean width difference of hip'was (6.73+/-1.01) mm; and the mean difference of the iliac crest was larger than that of mean difference of hip (P<0.01). The occurrence rate of inequal width of hip was higher(P<0.01). The mean abnormal lumbosacral angle was (7.29 +/- 1.86) degrees,and the mean angle of sacral crest tilting to left or right was (3.18 +/- 0.47) degrees; the mean abnormal lumbosacral angle was larger than that of angle of sacral crest tilting to left or right (P<0.01), and the occurrence rate of sacral crest tilting to left or right was higher

  19. How Often Do Thermally Excited 630.0 nm Emissions Occur in the Polar Ionosphere?

    NASA Astrophysics Data System (ADS)

    Kwagala, Norah Kaggwa; Oksavik, Kjellmar; Lorentzen, Dag A.; Johnsen, Magnar G.

    2018-01-01

    This paper studies thermally excited emissions in the polar ionosphere derived from European Incoherent Scatter Svalbard radar measurements from the years 2000-2015. The peak occurrence is found around magnetic noon, where the radar observations show cusp-like characteristics. The ionospheric, interplanetary magnetic field and solar wind conditions favor dayside magnetic reconnection as the dominant driving process. The thermal emissions occur 10 times more frequently on the dayside than on the nightside, with an average intensity of 1-5 kR. For typical electron densities in the polar ionosphere (2 × 1011 m-3), we find the peak occurrence rate to occur for extreme electron temperatures (>3000 K), which is consistent with assumptions in literature. However, for extreme electron densities (>5 × 1011 m-3), we can now report on a completely new population of thermal emissions that may occur at much lower electron temperatures (˜2300 K). The empirical atmospheric model (NRLMSISE-00) suggests that the latter population is associated with enhanced neutral atomic oxygen densities.

  20. Occurrence of Deoxynivalenol and Zearalenone in Commercial Fish Feed: An Initial Study

    PubMed Central

    Pietsch, Constanze; Kersten, Susanne; Burkhardt-Holm, Patricia; Valenta, Hana; Dänicke, Sven

    2013-01-01

    The control of mycotoxins is a global challenge not only in human consumption but also in nutrition of farm animals including aquatic species. Fusarium toxins, such as deoxynivalenol (DON) and zearalenone (ZEN), are common contaminants of animal feed but no study reported the occurrence of both mycotoxins in fish feed so far. Here, we report for the first time the occurrence of DON and ZEN in samples of commercial fish feed designed for nutrition of cyprinids collected from central Europe. A maximal DON concentration of 825 μg kg−1 feed was found in one feed whereas average values of 289 μg kg−1 feed were noted. ZEN was the more prevalent mycotoxin but the concentrations were lower showing an average level of 67.9 μg kg−1 feed. PMID:23325300

  1. Three-Dimensional Dendrite Growth Within the Shrouds of Single Crystal Blades of a Nickel-Based Superalloy

    NASA Astrophysics Data System (ADS)

    Wang, Fu; Wu, Zining; Huang, Can; Ma, Dexin; Jakumeit, Jürgen; Bührig-Polaczek, Andreas

    2017-12-01

    The effect of withdrawal rates on the three-dimensional dendrite growth within the shrouds of single crystal blades during directional solidification was studied by both experiments and numerical simulations. The results showed that at given withdrawal rates, the dendrite pattern within the shrouds comprised three zones: primary dendrite zone, secondary dendrite spread zone, and a higher-order dendrite branched zone. With increasing withdrawal rate, the average primary dendrite arm spacing in the primary dendrite zone and the average secondary dendrite arm spacings in both the secondary dendrite spread zone and the higher-order dendrite branched zone were reduced. Independent of the variation in withdrawal rate, two analogous dendrite growth routes were observed within the shrouds of the employed blade geometry. These routes originated from the primary dendrites in the primary dendrite zone and filled in the shrouds by directly spreading secondary or successively branching higher-order dendrites. Except for a withdrawal rate of 6 mm min-1, these dendrites impinged at the shroud's highest extremity and could be explained by the simulated moving isotherms. As the withdrawal rate was increased to 2.5 mm min-1, undercooling and contraction stress-related equiaxed grains were observed in the interdendritic region at the lowest shroud extremity. With increasing withdrawal rate, the amount of the defects was increased. Since the defects destroy the integrity of single crystal blades, the solidification condition within the shroud should be controlled to avoid their occurrence. Along the dendrite growth route, an accumulated misorientation of the dendrites was observed. At the same positions, this accumulation increased with increasing withdrawal rate.

  2. The Occurrence Rate of Hot Jupiters

    NASA Astrophysics Data System (ADS)

    Rampalli, Rayna; Catanzarite, Joseph; Batalha, Natalie M.

    2017-01-01

    As the first kind of exoplanet to be discovered, hot Jupiters have always been objects of interest. Despite being prevalent in radial velocity and ground-based surveys, they were found to be much rarer based on Kepler observations. These data show a pile-up at radii of 9-22 Rearth and orbital periods of 1-10 days. Computing accurate occurrence rates can lend insight into planet-formation and migration-theories. To get a more accurate look, the idea of reliability was introduced. Each hot Jupiter candidate was assigned a reliability based on its location in the galactic plane and likelihood of being a false positive. Numbers were updated if ground-based follow-up indicated a candidate was indeed a false positive. These reliabilities were introduced into an occurrence rate calculation and yielded about a 12% decrease in occurrence rate for each period bin examined and a 25% decrease across all the bins. To get a better idea of the cause behind the pileup, occurrence rates based on parent stellar metallicity were calculated. As expected from previous work, higher metallicity stars yield higher occurrence rates. Future work includes examining period distributions in both the high metallicity and low metallicity sample for a better understanding and confirmation of the pile-up effect.

  3. Solar Flare Occurrence Rate and Probability in Terms of the Sunspot Classification Supplemented with Sunspot Area and Its Changes

    NASA Astrophysics Data System (ADS)

    Lee, K.; Moon, Y.; Lee, J.; Na, H.; Lee, K.

    2013-12-01

    We investigate the solar flare occurrence rate and daily flare probability in terms of the sunspot classification supplemented with sunspot area and its changes. For this we use the NOAA active region data and GOES solar flare data for 15 years (from January 1996 to December 2010). We consider the most flare-productive 11 sunspot classes in the McIntosh sunspot group classification. Sunspot area and its changes can be a proxy of magnetic flux and its emergence/cancellation, respectively. We classify each sunspot group into two sub-groups by its area: 'Large' and 'Small'. In addition, for each group, we classify it into three sub-groups according to sunspot area changes: 'Decrease', 'Steady', and 'Increase'. As a result, in the case of compact groups, their flare occurrence rates and daily flare probabilities noticeably increase with sunspot group area. We also find that the flare occurrence rates and daily flare probabilities for the 'Increase' sub-groups are noticeably higher than those for the other sub-groups. In case of the (M + X)-class flares in the ';Dkc' group, the flare occurrence rate of the 'Increase' sub-group is three times higher than that of the 'Steady' sub-group. The mean flare occurrence rates and flare probabilities for all sunspot groups increase with the following order: 'Decrease', 'Steady', and 'Increase'. Our results statistically demonstrate that magnetic flux and its emergence enhance the occurrence of major solar flares.

  4. Slow but not low: genomic comparisons reveal slower evolutionary rate and higher dN/dS in conifers compared to angiosperms

    PubMed Central

    2012-01-01

    Background Comparative genomics can inform us about the processes of mutation and selection across diverse taxa. Among seed plants, gymnosperms have been lacking in genomic comparisons. Recent EST and full-length cDNA collections for two conifers, Sitka spruce (Picea sitchensis) and loblolly pine (Pinus taeda), together with full genome sequences for two angiosperms, Arabidopsis thaliana and poplar (Populus trichocarpa), offer an opportunity to infer the evolutionary processes underlying thousands of orthologous protein-coding genes in gymnosperms compared with an angiosperm orthologue set. Results Based upon pairwise comparisons of 3,723 spruce and pine orthologues, we found an average synonymous genetic distance (dS) of 0.191, and an average dN/dS ratio of 0.314. Using a fossil-established divergence time of 140 million years between spruce and pine, we extrapolated a nucleotide substitution rate of 0.68 × 10-9 synonymous substitutions per site per year. When compared to angiosperms, this indicates a dramatically slower rate of nucleotide substitution rates in conifers: on average 15-fold. Coincidentally, we found a three-fold higher dN/dS for the spruce-pine lineage compared to the poplar-Arabidopsis lineage. This joint occurrence of a slower evolutionary rate in conifers with higher dN/dS, and possibly positive selection, showcases the uniqueness of conifer genome evolution. Conclusions Our results are in line with documented reduced nucleotide diversity, conservative genome evolution and low rates of diversification in conifers on the one hand and numerous examples of local adaptation in conifers on the other hand. We propose that reduced levels of nucleotide mutation in large and long-lived conifer trees, coupled with large effective population size, were the main factors leading to slow substitution rates but retention of beneficial mutations. PMID:22264329

  5. Some limitations of frequency as a component of risk: an expository note.

    PubMed

    Cox, Louis Anthony

    2009-02-01

    Students of risk analysis are often taught that "risk is frequency times consequence" or, more generally, that risk is determined by the frequency and severity of adverse consequences. But is it? This expository note reviews the concepts of frequency as average annual occurrence rate and as the reciprocal of mean time to failure (MTTF) or mean time between failures (MTBF) in a renewal process. It points out that if two risks (represented as two (frequency, severity) pairs for adverse consequences) have identical values for severity but different values of frequency, then it is not necessarily true that the one with the smaller value of frequency is preferable-and this is true no matter how frequency is defined. In general, there is not necessarily an increasing relation between the reciprocal of the mean time until an event occurs, its long-run average occurrences per year, and other criteria, such as the probability or expected number of times that it will happen over a specific interval of interest, such as the design life of a system. Risk depends on more than frequency and severity of consequences. It also depends on other information about the probability distribution for the time of a risk event that can become lost in simple measures of event "frequency." More flexible descriptions of risky processes, such as point process models can avoid these limitations.

  6. Rocky mountain spotted fever hospitalizations among American Indians.

    PubMed

    Demma, Linda J; Holman, Robert C; Mikosz, Christina A; Curns, Aaron T; Swerdlow, David L; Paisano, Edna L; Cheek, James E

    2006-09-01

    To describe the epidemiology of Rocky Mountain spotted fever (RMSF) among American Indians/Alaska Natives (AI/ANs), we conducted a retrospective analysis of hospitalization records with an RMSF diagnosis using Indian Health Service (IHS) hospital discharge data for calendar years 1980-2003. A total of 261 RMSF hospitalizations were reported among AIs, for an average annual hospitalization rate of 1.21 per 100,000 persons; two deaths were reported (0.8%). Most hospitalizations (88.5%) occurred in the Southern Plains region, where the rate was 4.23 per 100,000 persons. Children 1-4 years of age had the highest age-specific hospitalization rate of 2.50 per 100,000 persons. The overall annual RMSF hospitalization rate declined during the study period. Understanding the epidemiology of RMSF among AI/ANs and educating IHS/tribal physicians on the diagnosis of tick-borne diseases remain important for the prompt treatment of RMSF and the reduction of the disease occurrence among AI/ANs, particularly in high-risk areas.

  7. Heart rate prediction for coronary artery disease patients (CAD): Results of a clinical pilot study.

    PubMed

    Müller-von Aschwege, Frerk; Workowski, Anke; Willemsen, Detlev; Müller, Sebastian M; Hein, Andreas

    2015-01-01

    This paper describes the results of a pilot study with cardiac patients based on information that can be derived from a smartphone. The idea behind the study is to design a model for estimating the heart rate of a patient before an outdoor walking session for track planning, as well as using the model for guidance during an outdoor session. The model allows estimation of the heart rate several minutes in advance to guide the patient and avoid overstrain before its occurrence. This paper describes the first results of the clinical pilot study with cardiac patients taking β-blockers. 9 patients have been tested on a treadmill and during three outdoor sessions each. The results have been derived and three levels of improvement have been tested by cross validation. The overall result is an average Median Absolute Deviation (MAD) of 4.26 BPM between measured heart rate and smartphone sensor based model estimation.

  8. Phytomass in southwest Alaska.

    Treesearch

    Bert R. Mead

    2000-01-01

    Phytomass tables are presented for southwest Alaska. The methods used to estimate plant weight and occurrence in the river basin are described and discussed. Average weight is shown for each sampled species of tree, shrub, grass, forb, lichen, and moss in 19 forest and 48 nonforest vegetation types. Species frequency of occurrence and species constancy within the type...

  9. Survival analysis of postoperative nausea and vomiting in patients receiving patient-controlled epidural analgesia.

    PubMed

    Lee, Shang-Yi; Hung, Chih-Jen; Chen, Chih-Chieh; Wu, Chih-Cheng

    2014-11-01

    Postoperative nausea and vomiting as well as postoperative pain are two major concerns when patients undergo surgery and receive anesthetics. Various models and predictive methods have been developed to investigate the risk factors of postoperative nausea and vomiting, and different types of preventive managements have subsequently been developed. However, there continues to be a wide variation in the previously reported incidence rates of postoperative nausea and vomiting. This may have occurred because patients were assessed at different time points, coupled with the overall limitation of the statistical methods used. However, using survival analysis with Cox regression, and thus factoring in these time effects, may solve this statistical limitation and reveal risk factors related to the occurrence of postoperative nausea and vomiting in the following period. In this retrospective, observational, uni-institutional study, we analyzed the results of 229 patients who received patient-controlled epidural analgesia following surgery from June 2007 to December 2007. We investigated the risk factors for the occurrence of postoperative nausea and vomiting, and also assessed the effect of evaluating patients at different time points using the Cox proportional hazards model. Furthermore, the results of this inquiry were compared with those results using logistic regression. The overall incidence of postoperative nausea and vomiting in our study was 35.4%. Using logistic regression, we found that only sex, but not the total doses and the average dose of opioids, had significant effects on the occurrence of postoperative nausea and vomiting at some time points. Cox regression showed that, when patients consumed a higher average dose of opioids, this correlated with a higher incidence of postoperative nausea and vomiting with a hazard ratio of 1.286. Survival analysis using Cox regression showed that the average consumption of opioids played an important role in postoperative nausea and vomiting, a result not found by logistic regression. Therefore, the incidence of postoperative nausea and vomiting in patients cannot be reliably determined on the basis of a single visit at one point in time. Copyright © 2014. Published by Elsevier Taiwan.

  10. Cross-species transmission potential between wild pigs, livestock, poultry, wildlife, and humans: Implications for disease risk management in North America

    USGS Publications Warehouse

    Miller, Ryan S.; Sweeney, Steven J.; Slootmaker, Chris; Grear, Daniel A.; DiSalvo, Paul A.; Kiser, Deborah; Shwiff, Stephanie A.

    2017-01-01

    Cross-species disease transmission between wildlife, domestic animals and humans is an increasing threat to public and veterinary health. Wild pigs are increasingly a potential veterinary and public health threat. Here we investigate 84 pathogens and the host species most at risk for transmission with wild pigs using a network approach. We assess the risk to agricultural and human health by evaluating the status of these pathogens and the co-occurrence of wild pigs, agriculture and humans. We identified 34 (87%) OIE listed swine pathogens that cause clinical disease in livestock, poultry, wildlife, and humans. On average 73% of bacterial, 39% of viral, and 63% of parasitic pathogens caused clinical disease in other species. Non-porcine livestock in the family Bovidae shared the most pathogens with swine (82%). Only 49% of currently listed OIE domestic swine diseases had published wild pig surveillance studies. The co-occurrence of wild pigs and farms increased annually at a rate of 1.2% with as much as 57% of all farms and 77% of all agricultural animals co-occurring with wild pigs. The increasing co-occurrence of wild pigs with livestock and humans along with the large number of pathogens shared is a growing risk for cross-species transmission.

  11. Cross-species transmission potential between wild pigs, livestock, poultry, wildlife, and humans: implications for disease risk management in North America.

    PubMed

    Miller, Ryan S; Sweeney, Steven J; Slootmaker, Chris; Grear, Daniel A; Di Salvo, Paul A; Kiser, Deborah; Shwiff, Stephanie A

    2017-08-10

    Cross-species disease transmission between wildlife, domestic animals and humans is an increasing threat to public and veterinary health. Wild pigs are increasingly a potential veterinary and public health threat. Here we investigate 84 pathogens and the host species most at risk for transmission with wild pigs using a network approach. We assess the risk to agricultural and human health by evaluating the status of these pathogens and the co-occurrence of wild pigs, agriculture and humans. We identified 34 (87%) OIE listed swine pathogens that cause clinical disease in livestock, poultry, wildlife, and humans. On average 73% of bacterial, 39% of viral, and 63% of parasitic pathogens caused clinical disease in other species. Non-porcine livestock in the family Bovidae shared the most pathogens with swine (82%). Only 49% of currently listed OIE domestic swine diseases had published wild pig surveillance studies. The co-occurrence of wild pigs and farms increased annually at a rate of 1.2% with as much as 57% of all farms and 77% of all agricultural animals co-occurring with wild pigs. The increasing co-occurrence of wild pigs with livestock and humans along with the large number of pathogens shared is a growing risk for cross-species transmission.

  12. Bone cancer occurrence among beagles given 239Pu as young adults.

    PubMed

    Lloyd, R D; Taylor, G N; Angus, W; Bruenger, F W; Miller, S C

    1993-01-01

    The occurrence of skeletal malignancies has been documented among 234 young adult beagles given single intravenous injections of monomeric 239Pu citrate. Occurrence has also been documented among 132 comparable control group animals surviving the minimum latent time period of 2.79 y for radiation-induced bone cancer, who were maintained for lifespan observation. Injected amounts ranged from about 0.02-106 kBq kg-1 body mass with factors of 2 or 3 between dose levels. There were 84 radiographically apparent bone tumors in 76 plutonium-injected dogs and one tumor in a control group dog. Most of these were osteosarcomas except for seven chondrosarcomas, one liposarcoma, and one plasma cell myeloma of bone. The relationship between percent of dogs at any dose level with bone malignancy and average skeletal dose at the presumed time of tumor initiation of 1 y before death appeared to be linear below about 1.3 Gy average skeletal dose. The observed data can be approximated by the expression A = 0.76 + 75 D, where A = percent of dogs with bone cancer at any dose level, D = average skeletal dose in Gy (for doses up to 1.3 Gy) at tumor initiation, and 0.76 represents the percent tumor response in the control animals not given plutonium. Similar analysis of our corresponding data for beagles given 226Ra, excluding the two highest dose levels (approximately 100% occurrence), yielded the expression A = 0.76 + 4.7 D, where D = the average skeletal dose in Gy (for doses up to 20 Gy) at 1 y before death. The ratio of coefficients indicates the effectiveness for bone cancer induction of 239Pu relative to 226Ra, or [(75 +/- 22.5)(4.7 +/- 0.47)-1] = 16 +/- 5 for a single, brief intake of either nuclide into blood.

  13. El Niño-Southern Oscillation, local weather and occurrences of dengue virus serotypes

    NASA Astrophysics Data System (ADS)

    Huang, Xiaodong; Clements, Archie C. A.; Williams, Gail; Devine, Gregor; Tong, Shilu; Hu, Wenbiao

    2015-11-01

    Severe dengue fever is usually associated with secondary infection by a dengue virus (DENV) serotype (1 to 4) that is different to the serotype of the primary infection. Dengue outbreaks only occur following importations of DENV in Cairns, Australia. However, the majority of imported cases do not result in autochthonous transmission in Cairns. Although DENV transmission is strongly associated with the El Niño-Southern Oscillation (ENSO) climate cycle and local weather conditions, the frequency and potential risk factors of infections with the different DENV serotypes, including whether or not they differ, is unknown. This study used a classification tree model to identify the hierarchical interactions between Southern Oscillation Index (SOI), local weather factors, the presence of imported serotypes and the occurrence of the four autochthonous DENV serotypes from January 2000-December 2009 in Cairns. We found that the 12-week moving average of SOI and the 2-week moving average of maximum temperature were the most important factors influencing the variation in the weekly occurrence of the four DENV serotypes, the likelihoods of the occurrence of the four DENV serotypes may be unequal under the same environmental conditions, and occurrence may be influenced by changes in global and local environmental conditions in Cairns.

  14. Treatment refusal and premature termination in psychotherapy, pharmacotherapy, and their combination: A meta-analysis of head-to-head comparisons.

    PubMed

    Swift, Joshua K; Greenberg, Roger P; Tompkins, Kelley A; Parkin, Susannah R

    2017-03-01

    The purpose of this meta-analysis was to examine rates of treatment refusal and premature termination for pharmacotherapy alone, psychotherapy alone, pharmacotherapy plus psychotherapy, and psychotherapy plus pill placebo treatments. A systematic review of the literature resulted in 186 comparative trials that included a report of treatment refusal and/or premature termination for at least 2 of the 4 treatment conditions. The data from these studies were pooled using a random-effects analysis. Odds Ratio effect sizes were then calculated to compare the rates between treatment conditions, once across all studies and then again for specific client disorder categories. An average treatment refusal rate of 8.2% was found across studies. Clients who were assigned to pharmacotherapy were 1.76 times more likely to refuse treatment compared with clients who were assigned psychotherapy. Differences in refusal rates for pharmacotherapy and psychotherapy were particularly evident for depressive disorders, panic disorder, and social anxiety disorder. On average, 21.9% of clients prematurely terminated their treatment. Across studies, clients who were assigned to pharmacotherapy were 1.20 times more likely to drop out compared with clients who were assigned to psychotherapy. Pharmacotherapy clients with anorexia/bulimia and depressive disorders dropped out at higher rates compared with psychotherapy clients with these disorders. Treatment refusal and dropout are significant problems in both psychotherapy and pharmacotherapy and providers of these treatments should seek to employ strategies to reduce their occurrence. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  15. Monthly and Seasonal Cloud Cover Patterns at the Manila Observatory (14.64°N, 121.08°E)

    NASA Astrophysics Data System (ADS)

    Antioquia, C. T.; Lagrosas, N.; Caballa, K.

    2014-12-01

    A ground based sky imaging system was developed at the Manila Observatory in 2012 to measure cloud occurrence and to analyse seasonal variation of cloud cover over Metro Manila. Ground-based cloud occurrence measurements provide more reliable results compared to satellite observations. Also, cloud occurrence data aid in the analysis of radiation budget in the atmosphere. In this study, a GoPro Hero 2 with almost 180o field of view is employed to take pictures of the atmosphere. These pictures are taken continuously, having a temporal resolution of 1min. Atmospheric images from April 2012 to June 2013 (excluding the months of September, October, and November 2012) were processed to determine cloud cover. Cloud cover in an image is measured as the ratio of the number of pixels with clouds present in them to the total number of pixels. The cloud cover values were then averaged over each month to know its monthly and seasonal variation. In Metro Manila, the dry season occurs in the months of November to May of the next year, while the wet season occurs in the months of June to October of the same year. Fig 1 shows the measured monthly variation of cloud cover. No data was collected during the months of September (wherein the camera was used for the 7SEAS field campaign), October, and November 2012 (due to maintenance and repairs). Results show that there is high cloud cover during the wet season months (80% on average) while there is low cloud cover during the dry season months (62% on average). The lowest average cloud cover for a wet season month occurred in June 2012 (73%) while the highest average cloud cover for a wet season month occurred in June 2013 (86%). The variations in cloud cover average in this season is relatively smaller compared to that of the dry season wherein the lowest average cloud cover in a month was during April 2012 (38%) while the highest average cloud cover in a month was during January 2013 (77%); minimum and maximum averages being 39% apart. During the wet season, the cloud occurrence is mainly due to tropical storms, Southwest Monsoon, and local convection processes. In the dry season, less cloud is formed because of cold dry air from Northeast Monsoon (December to February) and generally dry and hot weather (March to May). Regular data collection has been implemented for further long term data analysis.

  16. Crisis occurrence and resolution in patients with severe and persistent mental illness: the contribution of suicidality.

    PubMed

    Links, Paul S; Eynan, Rahel; Ball, Jeffrey S; Barr, Aiala; Rourke, Sean

    2005-01-01

    Assertive community treatment appears to have limited impact on the risk of suicide in persons with severe and persistent mental illness (SPMI). This exploratory prospective study attempts to understand this observation by studying the contribution of suicidality to the occurrence of crisis events in patients with SPMI. Specifically, an observer-rated measure of the need for hospitalization, the Crisis Triage Rating Scale, was completed at baseline, crisis occurrence, and resolution to determine how much the level of suicidality contributed to the deemed level of crisis. Second, observer-ratings of suicidal ideation, the Modified Scale for Suicide Ideation, and psychopathology and suicidality, Brief Psychiatric Rating Scale, were measured at baseline, crisis occurrence, and resolution. A self-report measure of distress, the Symptom Distress Scale, was completed at baseline, crisis occurrence, and resolution. Finally, the patients' crisis experiences were recorded qualitatively to compare with quantitative measures of suicidality. Almost 40% of the subjects experienced crisis events and more than a quarter of these events were judged to be severe enough to warrant the need for hospitalization. Our findings suggest that elevation of psychiatric symptoms is a major contributor to the crisis occurrences of individuals with SPMI; although the risk of suicide may have to be conceived as somewhat separate from crisis occurrence.

  17. High pressure jet injection of viscous solutions for endoscopic submucosal dissection (ESD): first clinical experience.

    PubMed

    Pioche, Mathieu; Lépilliez, Vincent; Déprez, Pierre; Giovannini, Marc; Caillol, Fabrice; Piessevaux, Hubert; Rivory, Jérôme; Guillaud, Olivier; Ciocîrlan, Mihai; Salmon, Damien; Lienhart, Isabelle; Lafon, Cyril; Saurin, Jean-Christophe; Ponchon, Thierry

    2015-08-01

    Long lasting elevation is a key factor during endoscopic submucosal dissection (ESD) and can be obtained by water jet injection of saline solution or by viscous macromolecular solutions. In a previous animal study, we assessed the Nestis Enki II system to combine jet injection and viscous solutions. In the present work, we used this combination in humans in different sites of the digestive tract. We retrospectively report all of the consecutive ESD procedures performed with jet injection of viscous solutions in four centers. Information was collected about the lesion, the procedure, the histological result, and the outcomes for the patient. In total, 45 resections were completed by six operators: five experts and one beginner with only one previous experience in human ESD. Lesions were located in the esophagus (10), the stomach (11), the duodenum (1), the colon (1) and the rectum (22). Average maximal lesion diameter was 4.8 cm (SD 2.4, range 2 - 11 cm), average lesion surface area was 19.8 cm(2) (SD 17.7, range 2.2 - 72 cm(2)), and average duration of procedure was 79.9 min (SD 50.3 min, range 19 - 225 min). ESD could be conducted while the endoscope was retroflexed at its maximum in 26 cases. Four adverse events were observed: two diminutive perforations and two delayed bleeding occurrences treated conservatively. The R0 resection rate was 91.1 %. The catheter was obstructed in six occurrences of bleeding. Endoscopic submucosal dissection using high pressure injection of viscous macromolecular solutions is safe and effective in different parts of the digestive tract. It does not impede working with the endoscope in the maximal retroflexed position.

  18. Combining Site Occupancy, Breeding Population Sizes and Reproductive Success to Calculate Time-Averaged Reproductive Output of Different Habitat Types: An Application to Tricolored Blackbirds

    PubMed Central

    Holyoak, Marcel; Meese, Robert J.; Graves, Emily E.

    2014-01-01

    In metapopulations in which habitat patches vary in quality and occupancy it can be complicated to calculate the net time-averaged contribution to reproduction of particular populations. Surprisingly, few indices have been proposed for this purpose. We combined occupancy, abundance, frequency of occurrence, and reproductive success to determine the net value of different sites through time and applied this method to a bird of conservation concern. The Tricolored Blackbird (Agelaius tricolor) has experienced large population declines, is the most colonial songbird in North America, is largely confined to California, and breeds itinerantly in multiple habitat types. It has had chronically low reproductive success in recent years. Although young produced per nest have previously been compared across habitats, no study has simultaneously considered site occupancy and reproductive success. Combining occupancy, abundance, frequency of occurrence, reproductive success and nest failure rate we found that that large colonies in grain fields fail frequently because of nest destruction due to harvest prior to fledging. Consequently, net time-averaged reproductive output is low compared to colonies in non-native Himalayan blackberry or thistles, and native stinging nettles. Cattail marshes have intermediate reproductive output, but their reproductive output might be improved by active management. Harvest of grain-field colonies necessitates either promoting delay of harvest or creating alternative, more secure nesting habitats. Stinging nettle and marsh colonies offer the main potential sources for restoration or native habitat creation. From 2005–2011 breeding site occupancy declined 3x faster than new breeding colonies were formed, indicating a rapid decline in occupancy. Total abundance showed a similar decline. Causes of variation in the value for reproduction of nesting substrates and factors behind continuing population declines merit urgent investigation. The method we employ should be useful in other metapopulation studies for calculating time-averaged reproductive output for different sites. PMID:24817307

  19. Does Stress Result in You Exercising Less? Or Does Exercising Result in You Being Less Stressed? Or is it Both?

    PubMed Central

    Burg, Matthew M.; Schwartz, Joseph E.; Kronish, Ian M.; Diaz, Keith M.; Alcantara, Carmela; Duer-Hefele, Joan; Davidson, Karina W.

    2017-01-01

    Background Psychosocial stress contributes to heart disease in part by adversely affecting maintenance of health behaviors, while exercise can reduce stress. Assessing the bi-directional relationship between stress and exercise has been limited by lack of real-time data, and theoretical and statistical models. This lack may hinder efforts to promote exercise maintenance. Purpose We test the bi-directional relationship between stress and exercise using real-time data for the average person, and the variability – individual differences – in this relationship. Methods A single cohort randomized controlled experiment. Healthy young adults (n=79) who reported only intermittent exercise, completed 12 months of stress monitoring by ecological momentary assessment (at the beginning of, end of, and during the day), and continuous activity monitoring by Fitbit. A random coefficients linear mixed model was used to predict end-of-day stress from the occurrence/non-occurrence of exercise that day; a logistic mixed model was used to predict the occurrence/non-occurrence of exercise from ratings of anticipated stress. Separate regression analyses were also performed for each participant. Sensitivity analysis tested all models, restricted to the first 180 days of observation (prior to randomization). Results We found a significant average inverse (i.e., negative) effect of exercise on stress and of stress on exercise. There was significant between-person variability. Of N=69, exercise was associated with a stress reduction for 15, a stress increase for 2, and no change for the remainder. We also found that an increase in anticipated stress reported the previous night or that morning was associated with a significant 20–22% decrease (OR=0.78–0.80) in the odds of exercising that day. Of N=69, this increase in stress reduced the likelihood of exercise for 17, increased the odds for 1, and had no effect for the remainder. We were unable to identify psychosocial factors that moderate the individual differences in these effects. Conclusions The relationship of stress to exercise can be uni- or bi-directional, and varies from person to person. A precision medicine approach may improve exercise uptake. PMID:28290065

  20. Ground water in the carbonate rocks of the Franklin area, Tennessee

    USGS Publications Warehouse

    Zurawski, Ann; Burchett, C.R.

    1980-01-01

    A study of ground water in the Franklin area, Tennessee, was undertaken to fill a growing need for information on ground-water occurrence in the carbonate rocks of central Tennessee. Fifteen drilling sites were selected that had one or more of the following characteristics: medium- to thick-bedded limestones within 200 feet of land surface, structural lows, significant streamflow gains and losses, elongated sinkholes, straight stream reaches, linear features or other surface indications of solution cavities at depth. The 15 test wells produced from less than 1 to about 600 gallons per minute and had an average yield of 68 gallons per minute, measured while pumping the wells with compressed air. The average driller-reported yield for the area is five gallons per minute. Specific capacities for the four highest yielding wells ranged from 0.6 to 357 gallons per minute per foot of drawdown after 8 hours of pumping at rates ranging from 70 to 225 gallons per minute. Additional drilling at two sites revealed extensive solution openings. At one site, drawdown in five observation wells did not exceed 8.5 feet during 48 hours of pumping at an average rate of 502 gallons per minute. Raw water in the test wells meets most drinking-water standards and is of rather uniform quality from well to well and throughout the year. (USGS)

  1. Accounting for occurrences: an explanation for some novel tendencies in causal judgment from contingency information.

    PubMed

    White, Peter A

    2009-06-01

    Contingency information is information about empirical associations between possible causes and outcomes. In the present research, it is shown that, under some circumstances, there is a tendency for negative contingencies to lead to positive causal judgments and for positive contingencies to lead to negative causal judgments. If there is a high proportion of instances in which a candidate cause (CC) being judged is present, these tendencies are predicted by weighted averaging models of causal judgment. If the proportion of such instances is low, the predictions of weighted averaging models break down. It is argued that one of the main aims of causal judgment is to account for occurrences of the outcome. Thus, a CC is not given a high causal judgment if there are few or no occurrences of it, regardless of the objective contingency. This argument predicts that, if there is a low proportion of instances in which a CC is present, causal judgments are determined mainly by the number of Cell A instances (i.e., CC present, outcome occurs), and that this explains why weighted averaging models fail to predict judgmental tendencies under these circumstances. Experimental results support this argument.

  2. Spatial and seasonal responses of precipitation in the Ganges and Brahmaputra river basins to ENSO and Indian Ocean dipole modes: implications for flooding and drought

    USGS Publications Warehouse

    Pervez, Md Shahriar; Henebry, Geoffry M.

    2015-01-01

    We evaluated the spatial and seasonal responses of precipitation in the Ganges and Brahmaputra basins as modulated by the El Niño Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) modes using Global Precipitation Climatology Centre (GPCC) full data reanalysis of monthly global land-surface precipitation data from 1901 to 2010 with a spatial resolution of 0.5° × 0.5°. The GPCC monthly total precipitation climatology targeting the period 1951–2000 was used to compute gridded monthly anomalies for the entire time period. The gridded monthly anomalies were averaged for the years influenced by combinations of climate modes. Occurrences of El Niño alone significantly reduce (88% of the long-term average (LTA)) precipitation during the monsoon months in the western and southeastern Ganges Basin. In contrast, occurrences of La Niña and co-occurrences of La Niña and negative IOD events significantly enhance (110 and 109% of LTA in the Ganges and Brahmaputra Basin, respectively) precipitation across both basins. When El Niño co-occurs with positive IOD events, the impacts of El Niño on the basins' precipitation diminishes. When there is no active ENSO or IOD events (occurring in 41 out of 110 years), precipitation remains below average (95% of LTA) in the agriculturally intensive areas of Haryana, Uttar Pradesh, Rajasthan, Madhya Pradesh, and Western Nepal in the Ganges Basin, whereas precipitation remains average to above average (104% of LTA) across the Brahmaputra Basin. This pattern implies that a regular water deficit is likely, especially in the Ganges Basin, with implications for the agriculture sector due to its reliance on consistent rainfall for successful production. Historically, major droughts occurred during El Niño and co-occurrences of El Niño and positive IOD events, while major flooding occurred during La Niña and co-occurrences of La Niña and negative IOD events in the basins. This observational analysis will facilitate well-informed decision making in minimizing natural hazard risks and climate impacts on agriculture, and supports development of strategies ensuring optimized use of water resources in best management practice under a changing climate.

  3. Enhanced HTS hit selection via a local hit rate analysis.

    PubMed

    Posner, Bruce A; Xi, Hualin; Mills, James E J

    2009-10-01

    The postprocessing of high-throughput screening (HTS) results is complicated by the occurrence of false positives (inactive compounds misidentified as active by the primary screen) and false negatives (active compounds misidentified as inactive by the primary screen). An activity cutoff is frequently used to select "active" compounds from HTS data; however, this approach is insensitive to both false positives and false negatives. An alternative method that can minimize the occurrence of these artifacts will increase the efficiency of hit selection and therefore lead discovery. In this work, rather than merely using the activity of a given compound, we look at the presence and absence of activity among all compounds in its "chemical space neighborhood" to give a degree of confidence in its activity. We demonstrate that this local hit rate (LHR) analysis method outperforms hit selection based on ranking by primary screen activity values across ten diverse high throughput screens, spanning both cell-based and biochemical assay formats of varying biology and robustness. On average, the local hit rate analysis method was approximately 2.3-fold and approximately 1.3-fold more effective in identifying active compounds and active chemical series, respectively, than selection based on primary activity alone. Moreover, when applied to finding false negatives, this method was 2.3-fold better than ranking by primary activity alone. In most cases, novel hit series were identified that would have otherwise been missed. Additional uses of and observations regarding this HTS analysis approach are also discussed.

  4. Occurrence rate of ion upflow and downflow observed by the Poker Flat Incoherent Scatter Radar (PFISR)

    NASA Astrophysics Data System (ADS)

    Zou, S.; Lu, J.; Varney, R. H.

    2017-12-01

    This study aims to investigate the occurrence rate of ion upflow and downflow events in the auroral ionosphere, using a full 3-year (2011-2013) dataset collected by the Poker Flat Incoherent Scatter Radar (PFISR) at 65.5° magnetic latitude. Ion upflow and downflow events are defined if there are three consecutive data points larger/smaller than 100/-100 m/s in the ion field-aligned velocity altitude profile. Their occurrence rates have been evaluated as a function of magnetic local time (MLT), season, geomagnetic activity, solar wind and interplanetary magnetic field (IMF). We found that the ion upflows are twice more likely to occur on the nightside than the dayside, and have slightly higher occurrence rate near Fall equinox. In contrast, the ion downflow events are more likely to occur in the afternoon sector but also during Fall equinox. In addition, the occurrence rate of ion upflows on the nightside increases when the aurora electrojet index (AE) and planetary K index (Kp) increase, while the downflows measured on the dayside clearly increase as the AE and Kp increase. In general, the occurrence rate of ion upflows increases with enhanced solar wind and IMF drivers. This correlation is particularly strong between the upflows on the nightside and the solar wind dynamic pressure and IMF Bz. The lack of correlation of upflows on the dayside with these parameters is due to the location of PFISR, which is usually equatorward of the dayside auroral zone and within the nightside auroral zone under disturbed conditions. The occurrence rate of downflow at all MLTs does not show strong dependence on the solar wind and IMF conditions. However, it occurs much more frequently on the dayside when the IMF By is strongly positive, i.e., >10 nT and the IMF Bz is strongly negative, i.e., < -10 nT. We suggest that the increased occurrence rate of downflows on the dayside is associated with dayside storm-enhanced density and the plume.

  5. Smoking in top-grossing movies--United States, 2010.

    PubMed

    2011-07-15

    The National Cancer Institute has concluded that studies indicate a causal relationship between exposure to depictions of smoking in movies and youth smoking initiation. Adolescents in the top quartile of exposures to onscreen tobacco incidents have been found to be approximately twice as likely to begin smoking as those in the bottom quartile. The 2010 U.S. Department of Health and Human Services strategic plan to reduce tobacco use includes reducing youth exposure to onscreen smoking. To monitor tobacco use in movies, Thumbs Up! Thumbs Down! (TUTD), a project of Breathe California of Sacramento-Emigrant Trails, counts occurrences of tobacco incidents in U.S. top-grossing movies each year. This report updates a previous report with the latest TUTD findings. In 2010, the number of onscreen tobacco incidents in youth-rated (G, PG, or PG-13) movies continued a downward trend, decreasing 71.6% from 2,093 incidents in 2005 to 595 in 2010. Similarly, the average number of incidents per youth-rated movie decreased 66.2%, from 20.1 in 2005 to 6.8 in 2010. The degree of decline, however, varied substantially by motion picture company. The three companies with published policies designed to reduce tobacco use in their movies had an average decrease in tobacco incidents of 95.8%, compared with an average decrease of 41.7% among the three major motion picture companies and independents without policies. This finding indicates that an enforceable policy aimed at reducing tobacco use in youth-rated movies can lead to substantially fewer tobacco incidents in movies and help prevent adolescent initiation of smoking.

  6. Detection of cough signals in continuous audio recordings using hidden Markov models.

    PubMed

    Matos, Sergio; Birring, Surinder S; Pavord, Ian D; Evans, David H

    2006-06-01

    Cough is a common symptom of many respiratory diseases. The evaluation of its intensity and frequency of occurrence could provide valuable clinical information in the assessment of patients with chronic cough. In this paper we propose the use of hidden Markov models (HMMs) to automatically detect cough sounds from continuous ambulatory recordings. The recording system consists of a digital sound recorder and a microphone attached to the patient's chest. The recognition algorithm follows a keyword-spotting approach, with cough sounds representing the keywords. It was trained on 821 min selected from 10 ambulatory recordings, including 2473 manually labeled cough events, and tested on a database of nine recordings from separate patients with a total recording time of 3060 min and comprising 2155 cough events. The average detection rate was 82% at a false alarm rate of seven events/h, when considering only events above an energy threshold relative to each recording's average energy. These results suggest that HMMs can be applied to the detection of cough sounds from ambulatory patients. A postprocessing stage to perform a more detailed analysis on the detected events is under development, and could allow the rejection of some of the incorrectly detected events.

  7. Observations of the interplanetary magnetic field between 0.46 and 1 A.U. by the Mariner 10 spacecraft. Ph.D. Thesis - Catholic Univ. of Am.

    NASA Technical Reports Server (NTRS)

    Behannon, K. W.

    1976-01-01

    Almost continuous measurement of the interplanetary magnetic field (IMF) at a sampling rate of 25 vectors/sec was performed by the magnetic field experiment onboard the Mariner 10 spacecraft during the period November 3, 1973 to April 14, 1974, comprising approximately 5-2/3 solar rotations and extending in radial distance from the sun from 1 to 0.46 AU. A clearly discernible two-sector pattern of field polarity was observed during the last 3-1/2 months of the period, with the dominant polarity toward the sun below the solar equatorial plane. Two compound high-speed solar wind streams were also present during this period, one in each magnetic field sector. Relative fluctuations of the field in magnitude and direction were found to have large time variations, but on average the relative magnitude fluctuations were approximately constant over the range of heliocentric distance covered while the relative directional fluctuations showed a slight decrease on average with increasing distance. The occurrence rate of directional discontinuities was also found to decrease with increasing radial distance from the sun.

  8. Birth-cohort patterns of mortality from ulcerative colitis and peptic ulcer.

    PubMed

    Sonnenberg, Amnon

    2008-10-01

    The aim was to follow the time trends of mortality from ulcerative colitis and compare them with those of gastric and duodenal ulcer. Mortality data from 21 different countries between 1941 and 2004 were analyzed. The age-specific death rates of each individual country, as well as the average age-specific rates of all countries, were plotted against the periods of birth and death. The average trends of mortality from ulcerative colitis, gastric and duodenal ulcer reveal distinctive and unique birth-cohort patterns of all three diseases. Similar to both types of peptic ulcer, the risk of developing ulcerative colitis started to rise in successive generations born during the second half of the 19(th) century. It peaked shortly before the turn of the century and has continued to decline since then. The rise and fall in the occurrence of ulcerative colitis preceded those of both ulcer types. The birth-cohort pattern indicates that exposure to the relevant risk factors of ulcerative colitis occurs during early life. As the model of H. pylori and its associated birth-cohort patterns of gastric and duodenal ulcer suggest, an enteric infection provides a possible explanation for such temporal trends of ulcerative colitis as well.

  9. Quantifying temporal isolation: a modelling approach assessing the effect of flowering time differences on crop-to-weed pollen flow in sunflower

    PubMed Central

    Roumet, Marie; Cayre, Adeline; Latreille, Muriel; Muller, Marie-Hélène

    2015-01-01

    Flowering time divergence can be a crucial component of reproductive isolation between sympatric populations, but few studies have quantified its actual contribution to the reduction of gene flow. In this study, we aimed at estimating pollen-mediated gene flow between cultivated sunflower and a weedy conspecific sunflower population growing in the same field and at quantifying, how it is affected by the weeds' flowering time. For that purpose, we extended an existing mating model by including a temporal distance (i.e. flowering time difference between potential parents) effect on mating probabilities. Using phenological and genotypic data gathered on the crop and on a sample of the weedy population and its offspring, we estimated an average hybridization rate of approximately 10%. This rate varied strongly from 30% on average for weeds flowering at the crop flowering peak to 0% when the crop finished flowering and was affected by the local density of weeds. Our result also suggested the occurrence of other factors limiting crop-to-weed gene flow. This level of gene flow and its dependence on flowering time might influence the evolutionary fate of weedy sunflower populations sympatric to their crop relative. PMID:25667603

  10. Estimation of sediment deposits in the Ghézala reservoir in northern Tunisia

    NASA Astrophysics Data System (ADS)

    Mathlouthi, Majid; Lebdi, Fethi

    2018-04-01

    The control of sedimentation in a reservoir provides a global evaluation of the process of erosion and transportation of sediment. Knowledge of sedimentation is useful for reservoir management. Bathymetric surveys can be used to assess the silting volume of dams. The results of two surveys of the Ghézala dam reservoir in northern Tunisia are available. The measurements provide initial information about the quantity and variability of silting and the mechanism of sediment deposition. According to the results of measurements, the average annual specific sediment yield of the Ghézala dam watershed is estimated at 1851 t km-2 yr-1. The annual average sediment volume trapped varies from 23 000 m3 in 1993 to 66 692 m3 in 2011. The sedimentation rates increases from 0.20 to 0.57 % overtime. The results indicate interdependence between the specific erosion rates and the occurrence of soils on steep slopes. The pressure exerted on the soil by plowing as well as overgrazing to meet the needs of the population of this area has exposed the soil to continued deterioration manifested by increased erosion endangering the only source of revenue for the area.

  11. Mapping the accretion disc of the short period eclipsing binary SDSS J0926+3624

    NASA Astrophysics Data System (ADS)

    Schlindwein, Wagner; Baptista, Raymundo

    2018-05-01

    We report the analysis of time-series of optical photometry of SDSS J0926+3624 collected with the Liverpool Robotic Telescope between 2012 February and March while the object was in quiescence. We combined our median eclipse timing with those in the literature to revise the ephemeris and confirm that the binary period is increasing at a rate \\dot{P}=(3.2 ± 0.4)× 10^{-13} s/s. The light curves show no evidence of either the orbital hump produced by a bright spot at disc rim or of superhumps; the average out-of-eclipse brightness level is consistently lower than previously reported. The eclipse map from the average light curve shows a hot white dwarf surrounded by a faint, cool accretion disc plus enhanced emission along the gas stream trajectory beyond the impact point at the outer disc rim, suggesting the occurrence of gas stream overflow/penetration at that epoch. We estimate a disc mass input rate of \\dot{M}=(9 ± 1)× 10^{-12} M_⊙ yr^{-1}, more than an order of magnitude lower than that expected from binary evolution with conservative mass transfer.

  12. Model Simulation of Ionosphere Electron Density with Dynamic Transportation and Mechanism of Sporadic E Layers in Lower Part of Ionosphere

    NASA Astrophysics Data System (ADS)

    Lin, Y. C.; Chu, Y. H.

    2015-12-01

    There are many physical theories responsible for explanation the generation mechanism of sporadic E (Es) plasma irregularities. In middle latitude, it's generally believed that sporadic E layers occur in vertical ion convergent areas driven by horizontal neutral wind shear. The sporadic E layers appear characteristic of abundant metallic ion species (i.e., Fe+, Mg+, Na+), that lifetime are longer than molecular ions by a factor of several orders, have been demonstrated by rocket-borne mass spectrometric measurements. On the basic of the GPS Radio Occultation (RO), using the scintillations of the GPS signal-to-noise ratio and intense fluctuation of excess phase, the global and seasonal sporadic E layers occurrence rates could be retrieved. In our previous study we found there is averaged 10 kilometers shift in height between the COSMIC-retrieved sporadic E layer occurrence rate and the sporadic E occurrence rate modeled from considering the convergence/divergence of Fe+ vertical flux. There are many reasons that maybe result in the altitude differences, e.g., tidal wind with phase shift, electric field driven force, iron species distributions. In this research, the quantitative analyses for electric field drives Es layers translations in vertical direction are presented. The tidal wind driven sporadic E layers have been simulating by modeling several nonmetallic ions (O+(4S), O+(2D), O+(2p), N+, N2+, O2+, NO+) and metallic ions (Fe+, FeO2+, FeN2+, FeO+) with wind shear transportation. The simulation result shows the Fe+ particles accumulate at zonal wind shear convergent regions and form the thin sporadic E layers. With the electric field taking into account, the whole shape of sporadic E layers vertical shift 2~5 km that depending on what magnitude and direction of electric field is added.

  13. Incidence of narcolepsy before and after MF59-adjuvanted influenza A(H1N1)pdm09 vaccination in South Korean soldiers.

    PubMed

    Kim, Woo Jung; Lee, Sang Don; Lee, Eun; Namkoong, Kee; Choe, Kang-Won; Song, Joon Young; Cheong, Hee Jin; Jeong, Hye Won; Heo, Jung Yeon

    2015-09-11

    Previous reports mostly from Europe suggested an association between an occurrence of narcolepsy and an influenza A(H1N1)pdm09 vaccine adjuvanted with AS03 (Pandemrix(®)). During the 2009 H1N1 pandemic vaccination campaign, the Korean military performed a vaccination campaign with one type of influenza vaccine containing MF59-adjuvants. This study was conducted to investigate the background incidence rate of narcolepsy in South Korean soldiers and the association of the MF59-adjuvanted vaccine with the occurrence of narcolepsy in a young adult group. To assess the incidence of narcolepsy, we retrospectively reviewed medical records of suspicious cases of narcolepsy in 2007-2013 in the whole 20 military hospitals of the Korean military. The screened cases were classified according to the Brighton Collaboration case definition of narcolepsy. After obtaining the number of confirmed cases of narcolepsy per 3 months in 2007-2013, we compared the crude incidence rate of narcolepsy before and after the vaccination campaign. We included 218 narcolepsy suspicious cases in the initial review, which were screened by the diagnostic code on the computerized disease registry in 2007-2013. Forty-one cases were finally diagnosed with narcolepsy in 2007-2013 (male sex, 95%; median age, 21 years). The average background incidence rate of narcolepsy in Korean soldiers was 0.91 cases per 100,000 persons per year. During the 9 months before vaccination implementation (April to December 2009), 6 narcolepsy cases occurred, whereas during the next 9 months (January to September 2010) including the 3-month vaccination campaign, 5 cases occurred. The incidence of narcolepsy in South Korean soldiers was not increased after the pandemic vaccination campaign using the MF59-adjuvanted vaccine. Our results suggest that the MF59-adjuvanted H1N1 vaccine did not contribute to the occurrence of narcolepsy in this young adult group. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. [Greenhouse gardeners and sickness absence. A questionnaire study among greenhouse gardeners in Aarhus region].

    PubMed

    Pallesen, Ellen; Nielsen, Claus Vinther; Drews, Birgit Mammen

    2007-02-26

    The aim of the study was to examine sickness absence and risk factors for sickness absence in a population of greenhouse gardeners in the county of Arhus. The study was cross sectional and based on data from questionnaires sent to all employees and greenhouse gardens in the county. Greenhouse gardeners had an average of four days of sickness absence a year. Self-rated health was poorer than average of the Danish population in general. Female gender, age below 40 years, troublesome relationships to family and friends, "poor" physical working environment and job insecurity were all predictors for increased risk of sickness absence lasting more than two weeks a year. Sickness absence was low compared to the average of the Danish labour market. Considering poorer self-rated health and frequent occurrence of some of the above-mentioned predictors for increased risk of sickness absence--female gender, age below 40 years and for women, high exposure to "poor" physical working environment--an average sickness absence of only four days was a puzzle. The data from the study were not sufficient to explain this paradox. It might be due to compensating factors at work or at a personal level. It might be due to information bias, as sickness absence could be underestimated, but agreement between reported sickness absence from employees and greenhouse gardens diminished that probability. It might have been a consequence of selection bias, the "healthy workers'" effect. Employees with considerable sickness absence might have been dismissed for long-term absence or might have quit the job because they were not able to cope with it.

  15. Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3-16 years from multiple raters in six cohorts in the EU-ACTION project.

    PubMed

    Bartels, Meike; Hendriks, Anne; Mauri, Matteo; Krapohl, Eva; Whipp, Alyce; Bolhuis, Koen; Conde, Lucia Colodro; Luningham, Justin; Fung Ip, Hill; Hagenbeek, Fiona; Roetman, Peter; Gatej, Raluca; Lamers, Audri; Nivard, Michel; van Dongen, Jenny; Lu, Yi; Middeldorp, Christel; van Beijsterveldt, Toos; Vermeiren, Robert; Hankemeijer, Thomas; Kluft, Cees; Medland, Sarah; Lundström, Sebastian; Rose, Richard; Pulkkinen, Lea; Vuoksimaa, Eero; Korhonen, Tellervo; Martin, Nicholas G; Lubke, Gitta; Finkenauer, Catrin; Fanos, Vassilios; Tiemeier, Henning; Lichtenstein, Paul; Plomin, Robert; Kaprio, Jaakko; Boomsma, Dorret I

    2018-05-29

    Childhood aggression and its resulting consequences inflict a huge burden on affected children, their relatives, teachers, peers and society as a whole. Aggression during childhood rarely occurs in isolation and is correlated with other symptoms of childhood psychopathology. In this paper, we aim to describe and improve the understanding of the co-occurrence of aggression with other forms of childhood psychopathology. We focus on the co-occurrence of aggression and other childhood behavioural and emotional problems, including other externalising problems, attention problems and anxiety-depression. The data were brought together within the EU-ACTION (Aggression in Children: unravelling gene-environment interplay to inform Treatment and InterventiON strategies) project. We analysed the co-occurrence of aggression and other childhood behavioural and emotional problems as a function of the child's age (ages 3 through 16 years), gender, the person rating the behaviour (father, mother or self) and assessment instrument. The data came from six large population-based European cohort studies from the Netherlands (2x), the UK, Finland and Sweden (2x). Multiple assessment instruments, including the Child Behaviour Checklist (CBCL), the Strengths and Difficulties Questionnaire (SDQ) and Multidimensional Peer Nomination Inventory (MPNI), were used. There was a good representation of boys and girls in each age category, with data for 30,523 3- to 4-year-olds (49.5% boys), 20,958 5- to 6-year-olds (49.6% boys), 18,291 7- to 8-year-olds (49.0% boys), 27,218 9- to 10-year-olds (49.4% boys), 18,543 12- to 13-year-olds (48.9% boys) and 10,088 15- to 16-year-olds (46.6% boys). We replicated the well-established gender differences in average aggression scores at most ages for parental ratings. The gender differences decreased with age and were not present for self-reports. Aggression co-occurred with the majority of other behavioural and social problems, from both externalising and internalising domains. At each age, the co-occurrence was particularly prevalent for aggression and oppositional and ADHD-related problems, with correlations of around 0.5 in general. Aggression also showed substantial associations with anxiety-depression and other internalizing symptoms (correlations around 0.4). Co-occurrence for self-reported problems was somewhat higher than for parental reports, but we found neither rater differences, nor differences across assessment instruments in co-occurrence patterns. There were large similarities in co-occurrence patterns across the different European countries. Finally, co-occurrence was generally stable across age and sex, and if any change was observed, it indicated stronger correlations when children grew older. We present an online tool to visualise these associations as a function of rater, gender, instrument and cohort. In addition, we present a description of the full EU-ACTION projects, its first results and the future perspectives.

  16. Using NDVI to assess departure from average greenness and its relation to fire business

    Treesearch

    Robert E. Burgan; Roberta A. Hartford; Jeffery C. Eidenshink

    1996-01-01

    A new satellite-derived vegetation greenness map, departure from average, is designed to compare current-year vegetation greenness with average greenness for the same time of year. Live-fuel condition as portrayed on this map, and the calculated 1,000-hour fuel moistures, are compared to fire occurrence and area burned in Montana and Idaho during the 1993 and 1994 fire...

  17. Combining high-throughput sequencing with fruit body surveys reveals contrasting life-history strategies in fungi

    PubMed Central

    Ovaskainen, Otso; Schigel, Dmitry; Ali-Kovero, Heini; Auvinen, Petri; Paulin, Lars; Nordén, Björn; Nordén, Jenni

    2013-01-01

    Before the recent revolution in molecular biology, field studies on fungal communities were mostly confined to fruit bodies, whereas mycelial interactions were studied in the laboratory. Here we combine high-throughput sequencing with a fruit body inventory to study simultaneously mycelial and fruit body occurrences in a community of fungi inhabiting dead wood of Norway spruce. We studied mycelial occurrence by extracting DNA from wood samples followed by 454-sequencing of the ITS1 and ITS2 regions and an automated procedure for species identification. In total, we detected 198 species as mycelia and 137 species as fruit bodies. The correlation between mycelial and fruit body occurrences was high for the majority of the species, suggesting that high-throughput sequencing can successfully characterize the dominating fungal communities, despite possible biases related to sampling, PCR, sequencing and molecular identification. We used the fruit body and molecular data to test hypothesized links between life history and population dynamic parameters. We show that the species that have on average a high mycelial abundance also have a high fruiting rate and produce large fruit bodies, leading to a positive feedback loop in their population dynamics. Earlier studies have shown that species with specialized resource requirements are rarely seen fruiting, for which reason they are often classified as red-listed. We show with the help of high-throughput sequencing that some of these species are more abundant as mycelium in wood than what could be expected from their occurrence as fruit bodies. PMID:23575372

  18. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat

    PubMed Central

    Bryła, Marcin; Ksieniewicz-Woźniak, Edyta; Waśkiewicz, Agnieszka; Szymczyk, Krystyna; Jędrzejczak, Renata

    2018-01-01

    The presence of mycotoxins in cereal grain is a very important food safety factor. The occurrence of “masked” mycotoxins has been intensively investigated in recent years. In this study, the occurrence of nivalenol, deoxynivalenol-3-glucoside, and deoxynivalenol in 92 samples of winter wheat from Polish cultivars was determined. The frequency of the occurrence of deoxynivalenol and nivalenol in the samples was 83% and 70%, respectively. The average content of the analytes was: for deoxynivalenol 140.2 µg/kg (10.5–1265.4 µg/kg), for nivalenol 35.0 µg/kg (5.1–372.5 µg/kg). Deoxynivalenol-3-glucoside, the formation of which is connected with the biotransformation pathway in plants, was present in 27% of tested wheat samples; its average content was 41.9 µg/kg (15.8–137.5 µg/kg). The relative content of deoxynivalenol-3-glucoside (DON-3G) compared to deoxynivalenol (DON) in positive samples was 4–37%. Despite the high frequency of occurrence of these mycotoxins, the quality of wheat from the 2016 season was good. The maximum content of DON, as defined in EU regulations (1250 µg/kg), was exceeded in only one sample. Nevertheless, the presence of a glycosidic derivative of deoxynivalenol can increase the risk to food safety, as it can be hydrolyzed by intestinal microflora. PMID:29438296

  19. Cold-induced bradycardia in man during sleep in Arctic winter nights

    NASA Astrophysics Data System (ADS)

    Buguet, A. G. C.

    1987-03-01

    Two young male Caucasians volunteered for a study on the effects of cold exposure during night sleep in winter in the Arctic. The 14-day experiment was divided in three consecutive periods, baseline (2 nights), cold exposure (10 night) and recovery (2 nights). Both baseline and recovery data were obtained in neutral thermal conditions in a laboratory. The subjects slept in a sleeping bag under an unheated tent during the cold exposure. Apart from polysomnographic and body temperature recordings, electrocardiograms were taken through a telemetric system for safety purposes. Heart rates were noted at 5-min intervals and averaged hourly. In both environmental conditions, heart rate decreased within the first two hours of sleep. Comparison of the data obtained during cold exposure vs. thermal neutrality revealed lower values of heart rate in the cold, while body temperatures remained within normal range. This cold-induced bradycardia supervening during night sleep is discussed in terms of the occurrence of a vagal reflex preventing central blood pressure to rise.

  20. Regional Differences in Tropical Lightning Distributions.

    NASA Astrophysics Data System (ADS)

    Boccippio, Dennis J.; Goodman, Steven J.; Heckman, Stan

    2000-12-01

    Observations from the National Aeronautics and Space Administration Optical Transient Detector (OTD) and Tropical Rainfall Measuring Mission (TRMM)-based Lightning Imaging Sensor (LIS) are analyzed for variability between land and ocean, various geographic regions, and different (objectively defined) convective `regimes.' The bulk of the order-of-magnitude differences between land and ocean regional flash rates are accounted for by differences in storm spacing (density) and/or frequency of occurrence, rather than differences in storm instantaneous flash rates, which only vary by a factor of 2 on average. Regional variability in cell density and cell flash rates closely tracks differences in 85-GHz microwave brightness temperatures. Monotonic relationships are found with the gross moist stability of the tropical atmosphere, a large-scale `adjusted state' parameter. This result strongly suggests that it will be possible, using TRMM observations, to objectively test numerical or theoretical predictions of how mesoscale convective organization interacts with the larger-scale environment. Further parameters are suggested for a complete objective definition of tropical convective regimes.

  1. Annual Rates on Seismogenic Italian Sources with Models of Long-Term Predictability for the Time-Dependent Seismic Hazard Assessment In Italy

    NASA Astrophysics Data System (ADS)

    Murru, Maura; Falcone, Giuseppe; Console, Rodolfo

    2016-04-01

    The present study is carried out in the framework of the Center for Seismic Hazard (CPS) INGV, under the agreement signed in 2015 with the Department of Civil Protection for developing a new model of seismic hazard of the country that can update the current reference (MPS04-S1; zonesismiche.mi.ingv.it and esse1.mi.ingv.it) released between 2004 and 2006. In this initiative, we participate with the Long-Term Stress Transfer (LTST) Model to provide the annual occurrence rate of a seismic event on the entire Italian territory, from a Mw4.5 minimum magnitude, considering bins of 0.1 magnitude units on geographical cells of 0.1° x 0.1°. Our methodology is based on the fusion of a statistical time-dependent renewal model (Brownian Passage Time, BPT, Matthews at al., 2002) with a physical model which considers the permanent effect in terms of stress that undergoes a seismogenic source in result of the earthquakes that occur on surrounding sources. For each considered catalog (historical, instrumental and individual seismogenic sources) we determined a distinct rate value for each cell of 0.1° x 0.1° for the next 50 yrs. If the cell falls within one of the sources in question, we adopted the respective value of rate, which is referred only to the magnitude of the event characteristic. This value of rate is divided by the number of grid cells that fall on the horizontal projection of the source. If instead the cells fall outside of any seismic source we considered the average value of the rate obtained from the historical and the instrumental catalog, using the method of Frankel (1995). The annual occurrence rate was computed for any of the three considered distributions (Poisson, BPT and BPT with inclusion of stress transfer).

  2. A Data Analytics Approach to Discovering Unique Microstructural Configurations Susceptible to Fatigue

    NASA Astrophysics Data System (ADS)

    Jha, S. K.; Brockman, R. A.; Hoffman, R. M.; Sinha, V.; Pilchak, A. L.; Porter, W. J.; Buchanan, D. J.; Larsen, J. M.; John, R.

    2018-05-01

    Principal component analysis and fuzzy c-means clustering algorithms were applied to slip-induced strain and geometric metric data in an attempt to discover unique microstructural configurations and their frequencies of occurrence in statistically representative instantiations of a titanium alloy microstructure. Grain-averaged fatigue indicator parameters were calculated for the same instantiation. The fatigue indicator parameters strongly correlated with the spatial location of the microstructural configurations in the principal components space. The fuzzy c-means clustering method identified clusters of data that varied in terms of their average fatigue indicator parameters. Furthermore, the number of points in each cluster was inversely correlated to the average fatigue indicator parameter. This analysis demonstrates that data-driven methods have significant potential for providing unbiased determination of unique microstructural configurations and their frequencies of occurrence in a given volume from the point of view of strain localization and fatigue crack initiation.

  3. Use of Climatological Data in Weather Insurance.

    NASA Astrophysics Data System (ADS)

    Changnon, Stanley A.; Changnon, Joyce M.

    1990-05-01

    There are three major types of crop-related weather insurance: hail, all perlis, and rain insurance. The development of rates is an exercise in applied climatology, and the importance of the historical data selected for assessing risk (and developing rates) is revealed by the problems encountered by firms insuring against deficient summer rainfall during the drought of 1988. Extensive purchase of premiums costing $9 million for coverage ($400 million) in the Midwest occurred with buyers (farmers) apparently aware during May and June 1988 that an unusually dry event was in progress. The levels of loss (50% or less of average June-August rainfall) offered by insurance firms were exceeded throughout the Midwest. The firms attempted to refund the record number of premiums accepted in June, and in turn, 8000 farmers filed a class-action suit against the firms for failure to accept premiums and to provide coverage. The insurance firms ultimately settled by agreeing to pay $48 million in claims. The coverage offered was based on the most recent 25 years of data, and this unusually wet period did not represent the longer-term likelihood of areally extensive dry summers. Uses of climatic data by the insurance industry include planning for the occurrence of such extreme event considerations, plus point vs area probabilities of these anomalous events; choosing the periods to select for routinely establishing new rates (rerating is typically done an 2- to 10-year cycles); and for determining the averages most appropriate to use for rate levels and sales considerations.

  4. Statistical Signs of Social Influence on Suicides

    PubMed Central

    Melo, Hygor Piaget M.; Moreira, André A.; Batista, Élcio; Makse, Hernán A.; Andrade, José S.

    2014-01-01

    By treating the suicide as a social fact, Durkheim envisaged that suicide rates should be determined by the connections between people and society. Under the same framework, he considered that crime is bound up with the fundamental conditions of all social life. The social effect on the occurrence of homicides has been previously substantiated, and confirmed here, in terms of a superlinear scaling relation: by doubling the population of a Brazilian city results in an average increment of 135% in the number of homicides, rather than the expected isometric increase of 100%, as found, for example, for the mortality due to car crashes. Here we present statistical signs of the social influence on the suicide occurrence in cities. Differently from homicides (superlinear) and fatal events in car crashes (isometric), we find sublinear scaling behavior between the number of suicides and city population, with allometric power-law exponents, β = 0.84 ± 0.02 and 0.87 ± 0.01, for all cities in Brazil and US counties, respectively. Also for suicides in US, but using the Metropolitan Statistical Areas (MSAs), we obtain β = 0.88 ± 0.01. PMID:25174706

  5. Statistical Signs of Social Influence on Suicides

    NASA Astrophysics Data System (ADS)

    Melo, Hygor Piaget M.; Moreira, André A.; Batista, Élcio; Makse, Hernán A.; Andrade, José S.

    2014-09-01

    By treating the suicide as a social fact, Durkheim envisaged that suicide rates should be determined by the connections between people and society. Under the same framework, he considered that crime is bound up with the fundamental conditions of all social life. The social effect on the occurrence of homicides has been previously substantiated, and confirmed here, in terms of a superlinear scaling relation: by doubling the population of a Brazilian city results in an average increment of 135% in the number of homicides, rather than the expected isometric increase of 100%, as found, for example, for the mortality due to car crashes. Here we present statistical signs of the social influence on the suicide occurrence in cities. Differently from homicides (superlinear) and fatal events in car crashes (isometric), we find sublinear scaling behavior between the number of suicides and city population, with allometric power-law exponents, β = 0.84 +/- 0.02 and 0.87 +/- 0.01, for all cities in Brazil and US counties, respectively. Also for suicides in US, but using the Metropolitan Statistical Areas (MSAs), we obtain β = 0.88 +/- 0.01.

  6. Occurrence of four Anaplasma species with veterinary and public health significance in sheep, northwestern China.

    PubMed

    Yang, Jifei; Han, Rong; Niu, Qingli; Liu, Zhijie; Guan, Guiquan; Liu, Guangyuan; Luo, Jianxun; Yin, Hong

    2018-01-01

    The members of the genus Anaplasma are important tick-borne rickettsial bacteria of veterinary and public health significance. Domestic ruminants are important reservoir hosts for several Anaplasma species. In this study, the occurrence of Anaplasma spp. was investigated by PCR in domestic small ruminants from Gansu, northwestern China. The results showed a high prevalence of Anaplasma spp. (46.2%, 201/435) in sheep. The average infection rates were 5.7%, 24.4%, 28.0% and 18.2% for A. ovis, A. bovis, A. phagocytophilum and A. capra, respectively. Coinfection of different Anaplasma species occurred in 96 (22.1%) sheep. The infections of Anaplasma species in sheep were confirmed by sequencing of msp4, 16S rRNA and gltA genes. Sequence analysis revealed a novel A. capra genotype in sheep that was distinct from the isolates identified from patients in northeastern China. This study gives the first insight of presence of four distinct Anaplasma species with veterinary and medical significance in sheep in northwestern China. Copyright © 2017. Published by Elsevier GmbH.

  7. Statistical signs of social influence on suicides.

    PubMed

    Melo, Hygor Piaget M; Moreira, André A; Batista, Élcio; Makse, Hernán A; Andrade, José S

    2014-09-01

    By treating the suicide as a social fact, Durkheim envisaged that suicide rates should be determined by the connections between people and society. Under the same framework, he considered that crime is bound up with the fundamental conditions of all social life. The social effect on the occurrence of homicides has been previously substantiated, and confirmed here, in terms of a superlinear scaling relation: by doubling the population of a Brazilian city results in an average increment of 135% in the number of homicides, rather than the expected isometric increase of 100%, as found, for example, for the mortality due to car crashes. Here we present statistical signs of the social influence on the suicide occurrence in cities. Differently from homicides (superlinear) and fatal events in car crashes (isometric), we find sublinear scaling behavior between the number of suicides and city population, with allometric power-law exponents, β = 0.84 ± 0.02 and 0.87 ± 0.01, for all cities in Brazil and US counties, respectively. Also for suicides in US, but using the Metropolitan Statistical Areas (MSAs), we obtain β = 0.88 ± 0.01.

  8. Sulphur dioxide (SO2) emissions during the 2014-15 Fogo eruption, Cape Verde

    NASA Astrophysics Data System (ADS)

    Barrancos, José; Dionis, Samara; Quevedo, Roberto; Fernandes, Paulo; Rodríguez, Fátima; Pérez, Nemesio M.; Silva, Sónia; Cardoso, Nadir; Hernández, Pedro A.; Melián, Gladys V.; Padrón, Eleazar; Padilla, Germán; Asensio-Ramos, María; Calvo, David; Semedo, Helio; Alfama, Vera

    2015-04-01

    A new eruption started at Fogo volcanic island on November 23, 2014, an active stratovolcano, located in the SW of the Cape Verde Archipelago; rising over 6 km from the 4000m deep seafloor to the Pico do Fogo summit at 2829m above sea level (m.a.s.l.). Since settlement in the 15th century, 27 eruptions have been identified through analysis of incomplete written records (Ribeiro, 1960), with average time intervals of 20 yr and average duration of two months. The eruptions were mostly effusive (Hawaiian to Strombolian), with rare occurrences of highly explosive episodes including phreatomagmatic events (Day et al., 1999). This study reports sulphur dioxide (SO2) emission rate variations observed throughout the 2014-15 Fogo eruption, Cape Verde. More than 100 measurements of SO2 emission rate have been carried out in a daily basis by ITER/INVOLCAN/UNICV/OVCV/SNPC research team since November 28, 2014, five days after the eruption onset, by means of a miniDOAS using the traverse method with a car. The daily deviation obtained of the data is around 15%. Estimated SO2 emission rates ranged from 12,476 ± 981 to 492 ± 27 tons/day during the 2014-15 Fogo eruption until January 1, 2015. During this first five days of measurements, the observed SO2 emission rates were high with an average rate of 11,100 tons/day. On December 3, 2014 the SO2 emission rate dropped to values close to 4,000 tons/day, whereas few days later, on December 10, 2014, an increase to values close to 11,000 tons/day was recorded. Since then, SO2 emission rate has shown decrease trend to values close to 1,300 tons/day until December 21, 2014. The average of the observed SO2 emission rate was about 2,000 tons/day from December 21, 2014 to January 1, 2015, without detecting a specific either increasing or decreasing trend of the SO2 emission rate. The objective of this report is to clarify relations between the SO2 emission rate and surface eruptive activity during the 2014-15 Fogo eruption. Day, S. J., Heleno da Silva, S. I. N., and Fonseca, J. F. B. D.: A past giant lateral collapse and present-day flank instability of Fogo, Cape Verde Islands, J. Volcanol. Geotherm. Res., 94, 191-218, 1999. Ribeiro, O.: A ilha do Fogo e as suas erupções, 12a edição, Memórias, Série Geográfica, J. Inv. Ultramar, 1960.

  9. Mid-Type M Dwarf Planet Occurrence Rates

    NASA Astrophysics Data System (ADS)

    Hardegree-Ullman, Kevin; Cushing, Michael; Muirhead, Philip Steven

    2018-01-01

    Planet occurrence rates increase toward later spectral types; therefore, M dwarf systems are our most promising targets in the search for exoplanets. Stars in the original Kepler field were primarily characterized from photometry alone, resulting in large uncertainties (~30%) for properties of late-type stars like M dwarfs. Planet occurrence rate calculations require precise measurements of stellar radii, which can be constrained to ~10% using temperatures and metallicities derived from spectra. These measurements need to be performed on a statistically significant population of stars, including systems with and without planets. Using WIYN, the Discovery Channel Telescope, and IRTF, we have gathered spectra of about half of the ~550 probable mid-type M dwarfs in the Kepler field. Our observations have led to better constraints on stellar parameters and new planet occurrence rates for mid-type M dwarfs. We gratefully acknowledge support from the NASA-NSF Exoplanet Observational Research partnership, the National Optical Astronomy Observatory, and the NASA Exoplanet Science Institute.

  10. The mean time-limited crash rate of stock price

    NASA Astrophysics Data System (ADS)

    Li, Yun-Xian; Li, Jiang-Cheng; Yang, Ai-Jun; Tang, Nian-Sheng

    2017-05-01

    In this article we investigate the occurrence of stock market crash in an economy cycle. Bayesian approach, Heston model and statistical-physical method are considered. Specifically, Heston model and an effective potential are employed to address the dynamic changes of stock price. Bayesian approach has been utilized to estimate the Heston model's unknown parameters. Statistical physical method is used to investigate the occurrence of stock market crash by calculating the mean time-limited crash rate. The real financial data from the Shanghai Composite Index is analyzed with the proposed methods. The mean time-limited crash rate of stock price is used to describe the occurrence of stock market crash in an economy cycle. The monotonous and nonmonotonous behaviors are observed in the behavior of the mean time-limited crash rate versus volatility of stock for various cross correlation coefficient between volatility and price. Also a minimum occurrence of stock market crash matching an optimal volatility is discovered.

  11. ASA grade and Charlson Comorbidity Index of spinal surgery patients: correlation with complications and societal costs.

    PubMed

    Whitmore, Robert G; Stephen, James H; Vernick, Coleen; Campbell, Peter G; Yadla, Sanjay; Ghobrial, George M; Maltenfort, Mitchell G; Ratliff, John K

    2014-01-01

    The Charlson Comorbidity Index (CCI) and the American Society of Anesthesiologists (ASA) Physical Status Classification System (ASA grade) are useful for predicting morbidity and mortality for a variety of disease processes. To evaluate CCI and ASA grade as predictors of complications after spinal surgery and examine the correlation between these comorbidity indices and the cost of care. Prospective observational study. All patients undergoing any spine surgery at a single academic tertiary center over a 6-month period. Direct health-care costs estimated from diagnosis related group and Current Procedural Terminology (CPT) codes. Demographic data, including all patient comorbidities, procedural data, and all complications, occurring within 30 days of the index procedure were prospectively recorded. Charlson Comorbidity Index was calculated from International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes and ASA grades determined from the operative record. Diagnosis related group and CPT codes were captured for each patient. Direct costs were estimated from a societal perspective using Medicare rates of reimbursement. A multivariable analysis was performed to assess the association of the CCI and ASA grade to the rate of complication and direct health-care costs. Two hundred twenty-six cases were analyzed. The average CCI score for the patient cohort was 0.92, and the average ASA grade was 2.65. The CCI and ASA grade were significantly correlated, with Spearman ρ of 0.458 (p<.001). Both CCI and ASA grade were associated with increasing body mass index (p<.01) and increasing patient age (p<.0001). Increasing CCI was associated with an increasing likelihood of occurrence of any complication (p=.0093) and of minor complications (p=.0032). Increasing ASA grade was significantly associated with an increasing likelihood of occurrence of a major complication (p=.0035). Increasing ASA grade showed a significant association with increasing direct costs (p=.0062). American Society of Anesthesiologists and CCI scores are useful comorbidity indices for the spine patient population, although neither was completely predictive of complication occurrence. A spine-specific comorbidity index, based on ICD-9-CM coding that could be easily captured from patient records, and which is predictive of patient likelihood of complications and mortality, would be beneficial in patient counseling and choice of operative intervention. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. The Precipitation Characteristics of ISCCP Tropical Weather States

    NASA Technical Reports Server (NTRS)

    Lee, Dongmin; Oreopoulos, Lazaros; Huffman, George J.; Rossow, William B.; Kang, In-Sik

    2011-01-01

    We examine the daytime precipitation characteristics of the International Satellite Cloud Climatology Project (ISCCP) weather states in the extended tropics (35 deg S to 35 deg N) for a 10-year period. Our main precipitation data set is the TRMM Multisatellite Precipitation Analysis 3B42 data set, but Global Precipitation Climatology Project daily data are also used for comparison. We find that the most convective weather state (WS1), despite an occurrence frequency below 10%, is the most dominant state with regard to surface precipitation, producing both the largest mean precipitation rates when present and the largest percent contribution to the total precipitation of the tropical zone of our study; yet, even this weather state appears to not precipitate about half the time. WS1 exhibits a modest annual cycle of domain-average precipitation rate, but notable seasonal shifts in its geographic distribution. The precipitation rates of the other weather states tend to be stronger when occurring before or after WS1. The relative contribution of the various weather states to total precipitation is different between ocean and land, with WS1 producing more intense precipitation on average over ocean than land. The results of this study, in addition to advancing our understanding of the current state of tropical precipitation, can serve as a higher order diagnostic test on whether it is distributed realistically among different weather states in atmospheric models.

  13. Rogue waves of the Kundu-Eckhaus equation in a chaotic wave field.

    PubMed

    Bayindir, Cihan

    2016-03-01

    In this paper we study the properties of the chaotic wave fields generated in the frame of the Kundu-Eckhaus equation (KEE). Modulation instability results in a chaotic wave field which exhibits small-scale filaments with a free propagation constant, k. The average velocity of the filaments is approximately given by the average group velocity calculated from the dispersion relation for the plane-wave solution; however, direction of propagation is controlled by the β parameter, the constant in front of the Raman-effect term. We have also calculated the probabilities of the rogue wave occurrence for various values of propagation constant k and showed that the probability of rogue wave occurrence depends on k. Additionally, we have showed that the probability of rogue wave occurrence significantly depends on the quintic and the Raman-effect nonlinear terms of the KEE. Statistical comparisons between the KEE and the cubic nonlinear Schrödinger equation have also been presented.

  14. [Human mercury exposure and irregular menstrual cycles in relation to artisanal gold mining in Colombia].

    PubMed

    Rodríguez-Villamizar, Laura Andrea; Jaimes, Diana Carolina; Manquián-Tejos, Adelaida; Sánchez, Luz Helena

    2015-08-01

    Artisanal mining commonly extracts gold with an amalgamation process that uses mercury. The reproductive effects from exposure to elemental mercury used in gold mining have not been sufficiently studied. To evaluate the effect of the exposure to elemental mercury used in gold mining on menstrual cycle regularity and the occurrence of miscarriages in Colombia. An analytical cross-sectional study was conducted. The participants were female residents of gold mining districts, with a history of exposure to elemental mercury. Menstrual regularity and the occurrence of miscarriages were compared between these women and an unexposed group. Exposure and outcome variables were registered based on a questionnaire which was evaluated for its test-retest reproducibility. Prevalence rates were calculated using a binomial model and goodness-of-fit was evaluated. A total of 72 women exposed to mercury and 121 unexposed women participated. The average time of exposure to mercury among exposed women was 19.58 ± 9.53 years. The adjusted prevalence of irregular menstruation over the last six months was higher in the group of women chronically exposed to mercury vapors (PR=1.59, 95% CI 0.93-2.73), while there was no difference in the proportion of women with a history of miscarriages. Exposure to elemental mercury used in artisanal gold mining may be associated with a higher prevalence of irregular menstrual cycles but not with the occurrence of miscarriage.

  15. Occurrence of multiple mycotoxins and other fungal metabolites in animal feed and maize samples from Egypt using LC-MS/MS.

    PubMed

    Abdallah, Mohamed F; Girgin, Gözde; Baydar, Terken; Krska, Rudolf; Sulyok, Michael

    2017-10-01

    The present study aimed to investigate the occurrence of multiple toxic fungal and bacterial metabolites in 156 animal feed (n = 77) and maize (n = 79) samples collected from three regions in Upper Egypt. The target analytes were quantified using the 'dilute and shoot' approach, followed by a liquid chromatography tandem mass spectrometry analysis. In total, 115 fungal and bacterial metabolites were detected in both matrices, including the regulated mycotoxins in the European Union, in addition to the modified forms such as deoxynivalenol-3-glucosid. Furthermore, some Fusarium, Alternaria, Aspergillus and Penicillum metabolites beside other fungal and bacterial metabolites were detected for the first time in Egypt. All of the samples were contaminated with at least four toxins. On average, 26 different metabolites were detected per sample with a trend of more metabolites in feed than in maize. The maximum number of analytes observed per samples was 54 analytes at maximum concentrations ranging from 0.04 µg kg -1 for tentoxin to 25 040 µg kg -1 for kojic acid. According to the international standards, the contamination rates in the investigated regions were not alarming, except for AFB1 in maize. The necessity of further and continuous monitoring is highly recommended to establish a database for mycotoxin occurrence. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  16. Occurrence of acidic pharmaceuticals and personal care products in Turia River Basin: from waste to drinking water.

    PubMed

    Carmona, Eric; Andreu, Vicente; Picó, Yolanda

    2014-06-15

    The occurrence of 21 acidic pharmaceuticals, including illicit drugs, and personal care products (PPCPs) in waste, surface and drinking water and in sediments of the Turia River Basin (Valencia, Spain) was studied. A liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the determination of these PPCPs with electrospray (ESI) in negative ionization (NI) mode. Ammonium fluoride in the mobile phase improved ionization efficiency by an average increase in peak area of 5 compared to ammonium formate or formic acid. All studied compounds were detected and their concentration was waste water>surface water>drinking water. PPCPs were in waste water treatment plants (WWTPs) influents up to 7.26μgL(-1), dominated by ibuprofen, naproxen and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCOOH). WWTPs were highly effective in removing most of them, with an average removal rate of >90%. PPCPs were still detected in effluents in the 6.72-940ngL(-1) range, with the THCOOH, triclocarban, gemfibrozil and diclofenac as most prevalent. Similarly, diclofenac, gemfibrozil, ibuprofen, naproxen and propylparaben were detected quite frequently from the low ngL(-1) range to 7μgL(-1) in the surface waters of Turia River. Ibuprofen, methylparaben, salicylic acid and tetrahydrocannabinol (THC) were at concentrations up to 0.85ngg(-1) d.w. in sediments. The discharge of WWTP as well as of non-treated waters to this river is a likely explanation for the significant amount of PPCPs detected in surface waters and sediments. Mineral and tap waters also presented significant amounts (approx. 100ngL(-1)) of ibuprofen, naproxen, propylparaben and butylparaben. The occurrence at trace levels of several PPCPs in drinking water raises concerns about possible implications for human health. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Icing Frequencies Experienced During Climb and Descent by Fighter-Interceptor Aircraft

    NASA Technical Reports Server (NTRS)

    Perkins, Porter J.

    1958-01-01

    Data and analyses are presented on the relative frequencies of occurrence and severity of icing cloud layers encountered by jet aircraft in the climb and descent phases of flights to high altitudes. Fighter-interceptor aircraft operated by the Air Defense Command (USAF) at bases in the Duluth and Seattle areas collected the data with icing meters installed for a l-year period. The project was part of an extensive program conducted by the NACA to collect Icing cloud data for evaluating the icing problem relevant to routine operations. The average frequency of occurrence of icing was found to be about 5 percent of the number of climbs and descents during 1 year of operations The icing encounters were predominantly in the low and middle cloud layers, decreasing above 15,000 feet to practically none above 25,000 feet. The greatest thickness of ice that would accumulate on any aircraft component (as indicated by the accretion on a small object) was measured with the icing meters. The ice thicknesses on a small sensing probe averaged less than 1/32 inch and did not exceed 1/2 inch. Such accumulations are relatively small when compared with those that can form during horizontal flight in icing clouds. The light accretions resulted from relatively steep angles of flight through generally thin cloud layers. Because of the limited statistical reliability of the results, an analysis was made using previous statistics on icing clouds below an altitude of 20,000 feet to determine the general icing severity probabilities. The calculations were made using adiabatic lifting as a basis to establish the liquid-water content. Probabilities of over-all ice accretions on a small object as a function of airspeed and rate of climb were computed from the derived water contents. These results were then combined with the probability of occurrence of icing in order to give the icing severity that can be expected for routine aircraft operations.

  18. [Effect of integrated control of schistosomiasis in Shashi District from 2009 to 2013].

    PubMed

    Liu, Jin-Ming; Liao, Xian-Chao

    2014-10-01

    To evaluate the effect of integrated schistosomiasis control in Shashi District from 2009 to 2013, so as to provide the evidence for the development and adjustment of schistosomiasis control strategies. The data of integrated schistosomiasis control from 2009 to 2013 were collected and analyzed for the epidemic situations of human, livestock and Oncomelania hupensis snails. From 2009 to 2013, the infection rates of human and cattle decreased from 2.24% and 1.92% to 0.63% and 0, with decrease rates of 71.88% and 100%, respectively; the area with snails decreased from 760.40 hm2 to 715.08 hm2, with a decrease rate of 5.69%; the occurrence rate of frames with living snails and the average density of living snails decreased from 26.32% and 0.67 snail/0.1 m2 to 18.30% and 0.53 snail/0.1 mi2, with decrease rates of 30.47% and 20.90%, respectively. No infected living snails were found from 2012 to 2013. The integrated schistosomiasis prevention and control strategies with emphasis on infectious source control could effectively reduce the infection rates of human and cattle as well as the snail situation.

  19. Biases in Planet Occurrence Caused by Unresolved Binaries in Transit Surveys

    NASA Astrophysics Data System (ADS)

    Bouma, L. G.; Masuda, Kento; Winn, Joshua N.

    2018-06-01

    Wide-field surveys for transiting planets, such as the NASA Kepler and TESS missions, are usually conducted without knowing which stars have binary companions. Unresolved and unrecognized binaries give rise to systematic errors in planet occurrence rates, including misclassified planets and mistakes in completeness corrections. The individual errors can have different signs, making it difficult to anticipate the net effect on inferred occurrence rates. Here, we use simplified models of signal-to-noise limited transit surveys to try and clarify the situation. We derive a formula for the apparent occurrence rate density measured by an observer who falsely assumes all stars are single. The formula depends on the binary fraction, the mass function of the secondary stars, and the true occurrence of planets around primaries, secondaries, and single stars. It also takes into account the Malmquist bias by which binaries are over-represented in flux-limited samples. Application of the formula to an idealized Kepler-like survey shows that for planets larger than 2 R ⊕, the net systematic error is of order 5%. In particular, unrecognized binaries are unlikely to be the reason for the apparent discrepancies between hot-Jupiter occurrence rates measured in different surveys. For smaller planets the errors are potentially larger: the occurrence of Earth-sized planets could be overestimated by as much as 50%. We also show that whenever high-resolution imaging reveals a transit host star to be a binary, the planet is usually more likely to orbit the primary star than the secondary star.

  20. Impact of sleep duration on seizure frequency in adults with epilepsy: a sleep diary study.

    PubMed

    Cobabe, Maurine M; Sessler, Daniel I; Nowacki, Amy S; O'Rourke, Colin; Andrews, Noah; Foldvary-Schaefer, Nancy

    2015-02-01

    Prolonged sleep deprivation activates epileptiform EEG abnormalities and seizures in people with epilepsy. Few studies have addressed the effect of chronic partial sleep deprivation on seizure occurrence in populations with epilepsy. We tested the primary hypothesis that partial sleep deprivation over 24- and 72-hour periods increases seizure occurrence in adults with epilepsy. Forty-four subjects completed a series of self-reported instruments, as well as 1-month sleep and seizure diaries, to characterize their sleep and quality of life. Diaries were used to determine the relationship between seizure occurrence and total sleep time 24 and 72h before seizure occurrence using random effects models and a logistic regression model fit by generalized estimating equations. A total of 237 seizures were recorded during 1295 diary days, representing 5.5±7.0 (mean±SD) seizures per month. Random effects models for 24- and 72-hour total sleep times showed no clinically or statistically significant differences in the total sleep time between preseizure periods and seizure-free periods. The average 24-hour total sleep time during preseizure 24-hour periods was 8min shorter than that during seizure-free periods (p=0.51). The average 72-hour total sleep time during preseizure periods was 20min longer than that during seizure-free periods (p=0.86). The presence of triggers was a significant predictor of seizure occurrence, with stress/anxiety noted most often as a trigger. Mean total sleep time was 9h, and subjects took an average of 12±10 naps per month, having a mean duration of 1.9±1.2h. Daytime sleepiness, fatigue, and insomnia symptoms were commonly reported. Small degrees of sleep loss were not associated with seizure occurrence in our sample of adults with epilepsy. Our results also include valuable observations of the altered sleep times and frequent napping habits of adults with refractory epilepsy and the potential contribution of these habits to quality of life and seizure control. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Does garbage in diet improve Glaucous Gull reproductive output?

    USGS Publications Warehouse

    Powell, Abby N.; Weiser, Emily L.

    2010-01-01

    Anthropogenic subsidies are used by a variety of predators in areas developed for human use or residence. If subsidies promote population growth, these predators can have a negative effect on local prey species. The Glaucous Gull (Larus hyperboreus) is an abundant predator in northern Alaska that is believed to benefit from garbage as a supplemental food source, but this supposition has never been tested. In summer 2008 and 2009, we recorded the Glaucous Gull's diet and reproduction at 10 breeding colonies in northern Alaska. Colonies were in industrial, residential, and undeveloped areas and ranged from 5 to 75 km from the nearest landfill. By colony, garbage occurred in zero to 85% of pellets and food remains produced during the chick-rearing period, and the average number of chicks fledged per pair ranged from zero to 2.9. Random-forest analysis indicated that percent occurrence of garbage in the diet was the second most important factor (after number of eggs per pair) explaining variance in fledging rate. There was a significant positive correlation between percent occurrence of garbage in the diet and fledging rate in each year. If this correlation reflects a causal relationship, it suggests that human development that increases gulls' access to garbage could result in increased local gull populations. Such an increase could affect the gulls' natural prey species, including at least 14 species of shorebirds and waterfowl of conservation concern.

  2. Molluscicidal potential of Heterorhabditis baujardi (Rhabditida: Heterorhabditidae), strain LPP7, on Lymnaea columella (Gastropoda: Pulmonata): An alternative for biological control of fasciolosis.

    PubMed

    Tunholi, Victor Menezes; Lorenzoni, P O; da Silva, Ygor Henrique; Tunholi-Alves, Vinícius Menezes; Boeloni, Jankerle Neves; da Silva, Maria Aparecida; Monteiro, Caio Oliveira; Prata, M C A; Pinheiro, J; Martins, Isabella Vilhena Freire

    2017-09-01

    This study elucidated for the first time, under laboratory conditions, the susceptibility of Lymnaea columella to infective juveniles of Heterorhabditis baujardi LPP7. Exposure to the nematodes induced an average mortality rate of 66.66% in the population of L. columella, with the highest values attained from the second week after exposure onward. In addition, all the reproductive parameters analyzed (total number of eggs, number of egg masses, number of eggs laid/snail, embryo hatching rate and content of galactogen stored in the albumen gland) changed as a result of the infection. The results indicate the occurrence of the phenomenon of parasitic castration in L. columella infected by H. baujardi LPP7, probably through depletion of energy reserves such as galactogen, necessary to meet the intense metabolic demands of the nematode's larval stages. Finally, histopathological analysis demonstrated an intense process of cell disorganization, characterized by the occurrence of granulomatous inflammatory reactions in tissues of exposed snails, induced by the spoliative action of the bacteria/nematode. The results suggest the use of H. baujardi LPP7 as an alternative for biological control of the population of this intermediate host, and thus of the diseases in whose epidemiological chain it participates, especially fasciolosis, in line with the recommendations of the World Health Organization (WHO). Copyright © 2017. Published by Elsevier B.V.

  3. Lunar mare volcanism - Stratigraphy, eruption conditions, and the evolution of secondary crusts

    NASA Technical Reports Server (NTRS)

    Head, James W., III; Wilson, Lionel

    1992-01-01

    Recent developments in the geological analysis of lunar mare volcanism are reviewed. Analysis of returned samples and photogeological and remote sensing studies shows that mare volcanism began prior to the end of heavy bombardment (the period of cryptomare formation), in pre-Nectarian times, and continued until the Copernical Period, the total duration approaching 3.5-4 Ga. Stratigraphic analysis shows that the flux was not constant, but peaked in early lunar history, during the Imbrian Period. Average volcanic output rate during this period was about 0.01 cu cm/a. Volcanic landforms indicate that many eruptions were of high volume and long duration. Some eruptions associated with sinuous rills may have lasted a year and emplaced 1000 cu km of lava, representing the equivalent in one year of about 70,000 yr at the average flux. The occurrence of farside maria within craters whose diameter is generally near to or less than the thickness of the crust may be accounted for by the difference between local and regional compensation.

  4. Cloud Occurrence Measurements Over Sea during the 2nd 7 Southeast Asian Studies (7SEAS) Field Campaign in Palawan Archipelago

    NASA Astrophysics Data System (ADS)

    Antioquia, C. T.; Uy, S. N.; Caballa, K.; Lagrosas, N.

    2014-12-01

    Ground based sky imaging cameras have been used to measure cloud cover over an area to aid in radiation budget models. During daytime, certain clouds tend to help decrease atmospheric temperature by obstructing sunrays in the atmosphere. Thus, the detection of clouds plays an important role in the formulation of radiation budget in the atmosphere. In this study, a wide angled sky imager (GoPro Hero 2) was brought on board M/Y Vasco to detect and quantity cloud occurrence over sea during the 2nd 7SEAS field campaign. The camera is just a part of a number of scientific instruments used to measure weather, aerosol chemistry and solar radiation among others. The data collection started during the departure from Manila Bay on 05 September 2012 and went on until the end of the cruise (29 September 2012). The camera was placed in a weather-proof box that is then affixed on a steel mast where other instruments are also attached during the cruise. The data has a temporal resolution of 1 minute, and each image is 500x666 pixels in size. Fig. 1a shows the track of the ship during the cruise. The red, blue, hue, saturation, and value of the pixels are analysed for cloud occurrence. A pixel is considered to "contain" thick cloud if it passes all four threshold parameters (R-B, R/B, R-B/R+B, HSV; R is the red pixel color value, blue is the blue pixel color value, and HSV is the hue saturation value of the pixel) and considered thin cloud if it passes two or three parameters. Fig. 1b shows the daily analysis of cloud occurrence. Cloud occurrence here is quantified as the ratio of the pixels with cloud to the total number of pixels in the data image. The average cloud cover for the days included in this dataset is 87%. These measurements show a big contrast when compared to cloud cover over land (Manila Observatory) which is usually around 67%. During the duration of the cruise, only one day (September 6) has an average cloud occurrence below 50%; the rest of the days have averages of 66% or higher - 98% being the highest. This result would then give a general trend of how cloud occurrences over land and over sea differ in the South East Asian region. In this study, these cloud occurrences come from local convection and clouds brought about by Southwest Monsoon winds.

  5. Cow characteristics and their association with udder health after different dry period lengths.

    PubMed

    van Hoeij, R J; Lam, T J G M; de Koning, D B; Steeneveld, W; Kemp, B; van Knegsel, A T M

    2016-10-01

    Shortening or omitting the dry period (DP) in dairy cows is of interest because of potential beneficial effects on energy balance and metabolic health. Reported effects of a short or omitted dry period on udder health are ambiguous. This study aimed to evaluate the effect of no DP (0d), a short DP (30d), or a conventional DP (60 d) on the occurrence of intramammary infections (IMI) during the precalving period and on somatic cell counts (SCC), elevations of SCC (SCC≥200,000 cells/mL), and clinical mastitis in the subsequent lactation. The study also aimed to analyze which prepartum cow characteristics are associated with udder health after different DP lengths. Holstein-Friesian dairy cows (n=167) were randomly assigned to a DP length (0, 30, or 60 d). Cows with a 0-d DP had a greater occurrence of chronic IMI and a lower occurrence of cured IMI during the precalving period than cows with a 30-d or 60-d DP. Postpartum average SCC for lactation was greater in cows with a 0-d DP than in cows with a 30-d or 60-d DP. The number of cows with at least 1 elevation of SCC, the number of elevations of SCC per affected cow, the number of cows treated for clinical mastitis, and the number of cases of mastitis per affected cow did not differ among DP lengths. Cow characteristics related to postpartum average SCC for lactation were DP length, parity, and the following interactions: DP length with prepartum elevation of SCC, DP length with fat- and protein-corrected milk (FPCM) reduction between 150 and 67d prepartum, DP length with parity and with average SCC for lactation, and last FPCM before the conventional drying-off day with average SCC for lactation. Cows with prepartum parity 1 had a lower occurrence of at least 1 elevation of SCC in subsequent lactation compared with cows with parity >2. Last SCC before the conventional drying-off day was positively associated with occurrence of clinical mastitis in the subsequent lactation. In this study, DP length was not a risk factor for either elevation of SCC or occurrence of clinical mastitis in the subsequent lactation. The identified cow characteristics could be used in a decision support model to optimize DP length for individual cows. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  6. Environmental dose rate distribution along the Romanian Black Sea shore

    NASA Astrophysics Data System (ADS)

    Duliu, Octavian G.; Margineanu, Romul M.; Blebea-Apostu, Ana-Maria; Gomoiu, Claudia; Bercea, Sorin

    2013-04-01

    The radiometric investigation of the natural radioactivity dose rate distribution along the most important Romanian Black Sea tourist resorts showed values between 34 and 54 nSv/h, lower than the 59 nSv/h, the average background reported for the entire Romanian territory. At the same time we have noticed that the experimental dose rates monotonously increase northward, reaching a maximum in the vicinity of Vadu and Corbu beaches, both on the southern part of the Chituc sandbank. Concurrent gamma ray spectrometric measurements, performed at the Slanic-Prahova Low-Background Radiation Laboratory for sand samples collected from the same location, have shown that the natural radionuclides have a major contribution to background radiation while anthropogenic Cs-137 plays, 26 years after Chernobyl catastrophe, a negligible role. The experimental values of activity concentrations of all radionuclides present in sand samples were used to calculate the corresponding values of dose rates to which, by adding the contribution of cosmic rays, we have obtained values coincident, within experimental uncertainties, with the experimental ones. At the same time, on Chituc sandbank, a transverse profile of dose rate distribution revealed the presence of some local maxima, two to thee times higher then the average ones. Subsequent gamma ray spectrometry showed an increased content of natural radionuclides, most probably due to a local accumulation of heavy minerals, a common occurrence in the vicinity of river deltas, in our case the Danube Delta. In such a way, the monitoring of local dose rate distribution could be very useful not only in attesting the environmental quality of various resorts and beaches, but also, in signaling the presence of heavy minerals, with beneficent economic consequences.

  7. Evolution of lightning in an isolated hailstorm of moderate size in the tropics

    NASA Astrophysics Data System (ADS)

    Kamra, A. K.; Pawar, S. D.

    2007-10-01

    Evolution of lightning activity in a tropical hailstorm of moderate size that developed in the premonsoon season at Pune (18°32'N, 73°51'E, 559 m above sea level) is studied from the measurements of surface electric field, the Maxwell current and thunder. Total flash rate is counted from the electric field record, and the cloud-to-ground (CG) flash rate is estimated from the visual observations. Precise timings of their occurrence were confirmed from the observations of overshoot in the Maxwell current records. The storm exhibited an almost constant rate of one CG flash every 1 to 2 min over the whole life time of the storm. The ratio of intracloud (IC) to CG flashes (IC/CG) increased with the increase in total flash rate. In the convective stage of the storm, field changes from consecutive flashes were generally found to alternate in polarity. Moreover, in this stage, field changes occur in pairs, the first field change of each pair being of negative polarity and the second one of positive polarity. The two field changes in a pair occur with an average time difference of 14.3 ± 8.4 s while two consecutive pairs appear after 29.3 ± 9.1 s. In between the convective and mature stages, our observations suggest the occurrence of the phenomenon of rain gush and the field excursion associated with falling precipitation. Development of the mature stage was marked with rapid transitions in the surface electric field and the Maxwell current polarities from negative to positive. Further, total flash rate and IC/CG ratio sharply increase, and the lightning-induced electric field changes become almost exclusively of negative polarity. Observations suggest possibly a lifting up of the charging region in mature stage of the storm. The dissipating stage of the storm witnessed hail and rain showers, sharp transition of electric field and the Maxwell current from positive to negative polarity and occurrence of a few positive CG discharges. Our observations are consistent with the general belief that that some lightning flashes, by neutralizing and depositing charge in the region of opposite polarity, change the charge distribution so as to trigger another discharge in the storm.

  8. 10 CFR 140.92 - Appendix B-Form of indemnity agreement with licensees furnishing insurance policies as proof of...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Commission. 2.(a) For facilities designed for producing substantial amounts of electricity and having a rated... nuclear occurrence or series of occurrences at the location or in the course of transportation causing... radioactive material. (b) Any occurrence including an extraordinary nuclear occurrence or series of...

  9. 10 CFR 140.92 - Appendix B-Form of indemnity agreement with licensees furnishing insurance policies as proof of...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Commission. 2.(a) For facilities designed for producing substantial amounts of electricity and having a rated... nuclear occurrence or series of occurrences at the location or in the course of transportation causing... radioactive material. (b) Any occurrence including an extraordinary nuclear occurrence or series of...

  10. 10 CFR 140.92 - Appendix B-Form of indemnity agreement with licensees furnishing insurance policies as proof of...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Commission. 2.(a) For facilities designed for producing substantial amounts of electricity and having a rated... nuclear occurrence or series of occurrences at the location or in the course of transportation causing... radioactive material. (b) Any occurrence including an extraordinary nuclear occurrence or series of...

  11. 10 CFR 140.92 - Appendix B-Form of indemnity agreement with licensees furnishing insurance policies as proof of...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Commission. 2.(a) For facilities designed for producing substantial amounts of electricity and having a rated... nuclear occurrence or series of occurrences at the location or in the course of transportation causing... radioactive material. (b) Any occurrence including an extraordinary nuclear occurrence or series of...

  12. 10 CFR 140.92 - Appendix B-Form of indemnity agreement with licensees furnishing insurance policies as proof of...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commission. 2.(a) For facilities designed for producing substantial amounts of electricity and having a rated... nuclear occurrence or series of occurrences at the location or in the course of transportation causing... radioactive material. (b) Any occurrence including an extraordinary nuclear occurrence or series of...

  13. Congenital Microphthalmia, Anophthalmia and Coloboma among Live Births in Denmark.

    PubMed

    Roos, Laura; Jensen, Hanne; Grønskov, Karen; Holst, René; Tümer, Zeynep

    2016-10-01

    This study aims to quantify the occurrence of the congenital eye malformations anophthalmia (AO), microphthalmia (MO) and coloboma among liveborn infants in Denmark, and to estimate the rate of chromosomal abnormalities in this group of patients. A cohort of patients born in 1995-2012 with diagnoses of MO/AO or coloboma was identified from the Danish National Patient Registry (DNPR), and their ocular and extra-ocular diagnoses were reviewed. In order to assess the occurrence of chromosomal abnormalities in the cohort, the data were cross-referenced with the Danish Cytogenetic Central Registry (DCCR). We identified 415 patients with MO/AO/coloboma in the DNPR. The total number of live births from 1995-2012 was 1,174,299, and the average birth prevalence of MO/AO/coloboma was 3.6/10,000 live births and of MO/AO was 1.2/10,000 live births. Extra-ocular abnormalities were observed in 32.1% of MO/AO cases and 21.7% of coloboma cases. Chromosome analysis was performed in 36.1% of the cohort, and 14.7% of cases had an abnormal karyotype. In 8.7% of the cohort, a chromosome microarray analysis was performed, and in 44.4% of cases, a possibly pathogenic copy number variation was observed. The birth prevalence of MO/AO/coloboma in Denmark has been steady at 3.6/10,000 live births during the last 17 years. The rate of syndromic cases was lower compared to other studies. A relatively high rate of pathogenic chromosomal aberrations was observed, suggesting an important role for cytogenetic analysis in this group of patients.

  14. Preliminary Development and Evaluation of Lightning Jump Algorithms for the Real-Time Detection of Severe Weather

    NASA Technical Reports Server (NTRS)

    Schultz, Christopher J.; Petersen, Walter A.; Carey, Lawrence D.

    2009-01-01

    Previous studies have demonstrated that rapid increases in total lightning activity (intracloud + cloud-to-ground) are often observed tens of minutes in advance of the occurrence of severe weather at the ground. These rapid increases in lightning activity have been termed "lightning jumps." Herein, we document a positive correlation between lightning jumps and the manifestation of severe weather in thunderstorms occurring across the Tennessee Valley and Washington D.C. A total of 107 thunderstorms were examined in this study, with 69 of the 107 thunderstorms falling into the category of non-severe, and 38 into the category of severe. From the dataset of 69 isolated non-severe thunderstorms, an average peak 1 minute flash rate of 10 flashes/min was determined. A variety of severe thunderstorm types were examined for this study including an MCS, MCV, tornadic outer rainbands of tropical remnants, supercells, and pulse severe thunderstorms. Of the 107 thunderstorms, 85 thunderstorms (47 non-severe, 38 severe) from the Tennessee Valley and Washington D.C tested 6 lightning jump algorithm configurations (Gatlin, Gatlin 45, 2(sigma), 3(sigma), Threshold 10, and Threshold 8). Performance metrics for each algorithm were then calculated, yielding encouraging results from the limited sample of 85 thunderstorms. The 2(sigma) lightning jump algorithm had a high probability of detection (POD; 87%), a modest false alarm rate (FAR; 33%), and a solid Heidke Skill Score (HSS; 0.75). A second and more simplistic lightning jump algorithm named the Threshold 8 lightning jump algorithm also shows promise, with a POD of 81% and a FAR of 41%. Average lead times to severe weather occurrence for these two algorithms were 23 minutes and 20 minutes, respectively. The overall goal of this study is to advance the development of an operationally-applicable jump algorithm that can be used with either total lightning observations made from the ground, or in the near future from space using the GOES-R Geostationary Lightning Mapper.

  15. Mars Atmospheric CO2 Condensation Above the North and South Poles as Revealed by Radio Occultation, Climate Sounder, and Laser Ranging Observations

    NASA Technical Reports Server (NTRS)

    Hu, Renyu; Cahoy, Kerri; Zuber, Maria T.

    2012-01-01

    We study the condensation of CO2 in Mars atmosphere using temperature profilesretrieved from radio occultation measurements from Mars Global Surveyor (MGS) as wellas the climate sounding instrument onboard the Mars Reconnaissance Orbiter (MRO),and detection of reflective clouds by the MGS Mars Orbiter Laser Altimeter (MOLA). Wefind 11 events in 1999 where MGS temperature profiles indicate CO2 condensation andMOLA simultaneously detects reflective clouds. We thus provide causal evidence thatMOLA non-ground returns are associated with CO2 condensation, which strongly indicatestheir nature being CO2 clouds. The MGS and MRO temperature profiles together revealthe seasonal expansion and shrinking of the area and the vertical extent of atmosphericsaturation. The occurrence rate of atmospheric saturation is maximized at high latitudes inthe middle of winter. The atmospheric saturation in the northern polar region exhibits moreintense seasonal variation than in the southern polar region. In particular, a shrinking ofsaturation area and thickness from LS 270 to 300 in 2007 is found; this is probablyrelated to a planet-encircling dust storm. Furthermore, we integrate the condensation areaand the condensation occurrence rate to estimate cumulative masses of CO2 condensatesdeposited onto the northern and southern seasonal polar caps. The precipitation flux isapproximated by the particle settling flux which is estimated using the impulse responses ofMOLA filter channels. With our approach, the total atmospheric condensation mass canbe estimated from these observational data sets with average particle size as the onlyfree parameter. By comparison with the seasonal polar cap masses inferred from thetime-varying gravity of Mars, our estimates indicate that the average condensate particleradius is 822 mm in the northern hemisphere and 413 mm in the southern hemisphere.Our multi-instrument data analysis provides new constraints on modeling the global climateof Mars.

  16. Mars atmospheric CO2 condensation above the north and south poles as revealed by radio occultation, climate sounder, and laser ranging observations

    NASA Astrophysics Data System (ADS)

    Hu, Renyu; Cahoy, Kerri; Zuber, Maria T.

    2012-07-01

    We study the condensation of CO2 in Mars' atmosphere using temperature profiles retrieved from radio occultation measurements from Mars Global Surveyor (MGS) as well as the climate sounding instrument onboard the Mars Reconnaissance Orbiter (MRO), and detection of reflective clouds by the MGS Mars Orbiter Laser Altimeter (MOLA). We find 11 events in 1999 where MGS temperature profiles indicate CO2 condensation and MOLA simultaneously detects reflective clouds. We thus provide causal evidence that MOLA non-ground returns are associated with CO2 condensation, which strongly indicates their nature being CO2 clouds. The MGS and MRO temperature profiles together reveal the seasonal expansion and shrinking of the area and the vertical extent of atmospheric saturation. The occurrence rate of atmospheric saturation is maximized at high latitudes in the middle of winter. The atmospheric saturation in the northern polar region exhibits more intense seasonal variation than in the southern polar region. In particular, a shrinking of saturation area and thickness from LS ˜ 270° to ˜300° in 2007 is found; this is probably related to a planet-encircling dust storm. Furthermore, we integrate the condensation area and the condensation occurrence rate to estimate cumulative masses of CO2 condensates deposited onto the northern and southern seasonal polar caps. The precipitation flux is approximated by the particle settling flux which is estimated using the impulse responses of MOLA filter channels. With our approach, the total atmospheric condensation mass can be estimated from these observational data sets with average particle size as the only free parameter. By comparison with the seasonal polar cap masses inferred from the time-varying gravity of Mars, our estimates indicate that the average condensate particle radius is 8-22 μm in the northern hemisphere and 4-13 μm in the southern hemisphere. Our multi-instrument data analysis provides new constraints on modeling the global climate of Mars.

  17. VizieR Online Data Catalog: Planet occurrence rates calculated for KOIs (Mulders+, 2015)

    NASA Astrophysics Data System (ADS)

    Mulders, G. D.; Pascucci, I.; Apai, D.

    2016-03-01

    Planet occurrence rates are calculated using the methodology described in Mulders et al. (2015ApJ...798..112M). We use the planet candidate sample from Mullally et al. (2015, J/ApJS/217/31). (1 data file).

  18. Impact of repeated ivermectin treatments against onchocerciasis on the transmission of loiasis: an entomologic evaluation in central Cameroon.

    PubMed

    Kouam, Marc K; Tchatchueng-Mbougua, Jules B; Demanou, Maurice; Boussinesq, Michel; Pion, Sébastien D S; Kamgno, Joseph

    2013-09-27

    Annual community-directed treatment with ivermectin (CDTI) have been carried out since 1999 in the Lekie division (central region of Cameroon where most cases of Loa-related post ivermectin severe adverse events were reported) as part of the joined activities of the African Programme for Onchocerciasis Control (APOC) and Mectizan® Donation Program (MDP). As large-scale administration of ivermetine was demonstrated to be an efficient means to control loiasis transmission, it was hypothesized that CDTI would have lowered or halted the transmission of Loa loa in the Lekie division after 13 years of annual drug administration, indicating a possible reduction in the occurrence of Loa-related post-ivermectin severe adverse events. A 4-month entomologic study was carried out from March to June 2012 in the Lekie division to evaluate the impact of 13 years of CDTI on the transmission of L. loa whose baseline data were recorded in 1999-2000. There was a significant reduction in the infection rate for Chrysops silacea and C. dimidiata from 6.8 and 9% in 1999-2000 to 3 and 3.6% in 2012, respectively. The differences in the infective rate (IR) (percentage of flies harboring head L3 larvae), potential infective rate (PIR) (percentage of flies bearing L3 larvae), mean head L3 larvae load (MHL3) (average L3 per infective fly) and mean fly L3 larvae load (MFL3) (average L3 per potentially infective fly) for both C. silacea and C. dimidiata were not significantly different between the two investigation periods. The biting density (BD) was almost three-fold higher in 2012 for C. silacea but not for C. dimidiata. The transmission potential (TP) which is a function of the BD, was higher in the present study than in the baseline investigation for each species. The infection rate remaining high, the high TP and the stability observed in the IR, PIR, MHL3 and MFL3 after 13 years of CDTI suggest that transmission of L. loa is still active. This is an indication that the risk of occurrence of severe adverse events such as fatal encephalopathies is still present, especially for heavily microfilaria-loaded people taken ivermectin for the first time.

  19. Impact of repeated ivermectin treatments against onchocerciasis on the transmission of loiasis: an entomologic evaluation in central Cameroon

    PubMed Central

    2013-01-01

    Background Annual community-directed treatment with ivermectin (CDTI) have been carried out since 1999 in the Lekie division (central region of Cameroon where most cases of Loa-related post ivermectin severe adverse events were reported) as part of the joined activities of the African Programme for Onchocerciasis Control (APOC) and Mectizan® Donation Program (MDP). As large-scale administration of ivermetine was demonstrated to be an efficient means to control loiasis transmission, it was hypothesized that CDTI would have lowered or halted the transmission of Loa loa in the Lekie division after 13 years of annual drug administration, indicating a possible reduction in the occurrence of Loa-related post-ivermectin severe adverse events. Methods A 4-month entomologic study was carried out from March to June 2012 in the Lekie division to evaluate the impact of 13 years of CDTI on the transmission of L. loa whose baseline data were recorded in 1999–2000. Results There was a significant reduction in the infection rate for Chrysops silacea and C. dimidiata from 6.8 and 9% in 1999–2000 to 3 and 3.6% in 2012, respectively. The differences in the infective rate (IR) (percentage of flies harboring head L3 larvae), potential infective rate (PIR) (percentage of flies bearing L3 larvae), mean head L3 larvae load (MHL3) (average L3 per infective fly) and mean fly L3 larvae load (MFL3) (average L3 per potentially infective fly) for both C. silacea and C. dimidiata were not significantly different between the two investigation periods. The biting density (BD) was almost three-fold higher in 2012 for C. silacea but not for C. dimidiata. The transmission potential (TP) which is a function of the BD, was higher in the present study than in the baseline investigation for each species. Conclusion The infection rate remaining high, the high TP and the stability observed in the IR, PIR, MHL3 and MFL3 after 13 years of CDTI suggest that transmission of L. loa is still active. This is an indication that the risk of occurrence of severe adverse events such as fatal encephalopathies is still present, especially for heavily microfilaria-loaded people taken ivermectin for the first time. PMID:24289520

  20. Wind Magnetic Clouds for the Period 2013 - 2015: Model Fitting, Types, Associated Shock Waves, and Comparisons to Other Periods

    NASA Astrophysics Data System (ADS)

    Lepping, R. P.; Wu, C.-C.; Berdichevsky, D. B.; Szabo, A.

    2018-04-01

    We give the results of parameter fitting of the magnetic clouds (MCs) observed by the Wind spacecraft for the three-year period 2013 to the end of 2015 (called the "Present" period) using the MC model of Lepping, Jones, and Burlaga ( J. Geophys. Res. 95, 11957, 1990). The Present period is almost coincident with the solar maximum of the sunspot number, which has a broad peak starting in about 2012 and extending to almost 2015. There were 49 MCs identified in the Present period. The modeling gives MC quantities such as size, axial attitude, field handedness, axial magnetic-field strength, center time, and closest-approach vector. Derived quantities are also estimated, such as axial magnetic flux, axial current density, and total axial current. Quality estimates are assigned representing excellent, fair/good, and poor. We provide error estimates on the specific fit parameters for the individual MCs, where the poor cases are excluded. Model-fitting results that are based on the Present period are compared to the results of the full Wind mission from 1995 to the end of 2015 (Long-term period), and compared to the results of two other recent studies that encompassed the periods 2007 - 2009 and 2010 - 2012, inclusive. We see that during the Present period, the MCs are, on average, slightly slower, slightly weaker in axial magnetic field (by 8.7%), and larger in diameter (by 6.5%) than those in the Long-term period. However, in most respects, the MCs in the Present period are significantly closer in characteristics to those of the Long-term period than to those of the two recent three-year periods. However, the rate of occurrence of MCs for the Long-term period is 10.3 year^{-1}, whereas this rate for the Present period is 16.3 year^{-1}, similar to that of the period 2010 - 2012. Hence, the MC occurrence rate has increased appreciably in the last six years. MC Type (N-S, S-N, All N, All S, etc.) is assigned to each MC; there is an inordinately large percentage of All S, by about a factor of two compared to that of the Long-term period, indicating many strongly tipped MCs. In 2005, there was a distinct change in variability and average value (viewed at 1/2 year averages) of the duration, MC speed, axial magnetic field strength, axial magnetic flux, and total current to lower values. In the Present period, upstream shocks occur for 43% of the 49 cases; for comparison, the Long-term rate is 56%.

  1. No association of moon phase with stroke occurrence.

    PubMed

    Ruuskanen, Jori O; Sipilä, Jussi O T; Rautava, Päivi; Kytö, Ville

    2018-05-23

    Stroke occurrence shows strong correlations with sleep disorders and even subtle sleep disturbances have been shown to affect ischemic stroke (IS) occurrence. Chronobiology also exerts effects, like the morning surge in IS occurrence. Lunar cycles have also been shown to affect sleep and other physiological processes, but studies on moon phases and its possible association with occurrence of stroke are rare and nonconclusive. Therefore, we studied the effects of moon phases on stroke hospitalizations and in-hospital mortality nationwide in Finland in 2004-2014. All patients aged ≥18 years with IS or intracerebral hemorrhage (ICH) as primary discharge diagnosis were included. Daily number of admissions was treated as a response variable while moon phase, year and astronomical season were independent variables in Poisson regression modeling. We found no association between moon phases and stroke occurrence. The overall occurrence rates did not vary between different moon phases for IS or ICH (p = 0.61 or higher). There were no differences between moon phases in daily admission rates among men, women, young and old patients for any of the stroke subtypes. There was no difference in in-hospital mortality with regard to moon phase for IS or ICH overall (p = 0.19 or higher), nor in subgroup analyses. There were no significant interactions between moon phase and astronomical season for stroke occurrence or in-hospital mortality. To conclude, in this over a decade-long nationwide study including a total of 46 million person years of follow-up, we found no association between moon phases and occurrence or in-hospital mortality rates of IS or intracerebral hemorrhage.

  2. Can arsenic occurrence rate in bedrock aquifers be predicted?

    USGS Publications Warehouse

    Yang, Qiang; Jung, Hun Bok; Marvinney, Robert G.; Culbertson, Charles W.; Zheng, Yan

    2012-01-01

    A high percentage (31%) of groundwater samples from bedrock aquifers in the greater Augusta area, Maine was found to contain greater than 10 μg L–1 of arsenic. Elevated arsenic concentrations are associated with bedrock geology, and more frequently observed in samples with high pH, low dissolved oxygen, and low nitrate. These associations were quantitatively compared by statistical analysis. Stepwise logistic regression models using bedrock geology and/or water chemistry parameters are developed and tested with external data sets to explore the feasibility of predicting groundwater arsenic occurrence rates (the percentages of arsenic concentrations higher than 10 μg L–1) in bedrock aquifers. Despite the under-prediction of high arsenic occurrence rates, models including groundwater geochemistry parameters predict arsenic occurrence rates better than those with bedrock geology only. Such simple models with very few parameters can be applied to obtain a preliminary arsenic risk assessment in bedrock aquifers at local to intermediate scales at other localities with similar geology.

  3. Time-dependent Occurrence Rate of Electromagnetic Cyclotron Waves in the Solar Wind: Evidence for the Effect of Alpha Particles?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, G. Q.; Feng, H. Q.; Wu, D. J.

    Previous studies revealed that electromagnetic cyclotron waves (ECWs) near the proton cyclotron frequency exist widely in the solar wind, and the majority of ECWs are left-handed (LH) polarized waves. Using the magnetic field data from the STEREO mission, this Letter carries out a survey of ECWs over a long period of 7 years and calculates the occurrence rates of ECWs with different polarization senses. Results show that the occurrence rate is nearly a constant for the ECWs with right-handed polarization, but it varies significantly for the ECWs with LH polarization. Further investigation of plasma conditions reveals that the LH ECWsmore » take place preferentially in a plasma characterized by higher temperature, lower density, and larger velocity. Some considerable correlations between the occurrence rate of LH ECWs and the properties of ambient plasmas are discussed. The present research may provide evidence for the effect of alpha particles on the generation of ECWs.« less

  4. Can arsenic occurrence rates in bedrock aquifers be predicted?

    PubMed Central

    Yang, Qiang; Jung, Hun Bok; Marvinney, Robert G.; Culbertson, Charles W.; Zheng, Yan

    2012-01-01

    A high percentage (31%) of groundwater samples from bedrock aquifers in the greater Augusta area, Maine was found to contain greater than 10 µg L−1 of arsenic. Elevated arsenic concentrations are associated with bedrock geology, and more frequently observed in samples with high pH, low dissolved oxygen, and low nitrate. These associations were quantitatively compared by statistical analysis. Stepwise logistic regression models using bedrock geology and/or water chemistry parameters are developed and tested with external data sets to explore the feasibility of predicting groundwater arsenic occurrence rates (the percentages of arsenic concentrations higher than 10 µg L−1) in bedrock aquifers. Despite the under-prediction of high arsenic occurrence rates, models including groundwater geochemistry parameters predict arsenic occurrence rates better than those with bedrock geology only. Such simple models with very few parameters can be applied to obtain a preliminary arsenic risk assessment in bedrock aquifers at local to intermediate scales at other localities with similar geology. PMID:22260208

  5. The occurrence and wave properties of EMIC waves observed by the Magnetospheric Multiscale (MMS) mission

    NASA Astrophysics Data System (ADS)

    Wang, X. Y.; Huang, S. Y.; Allen, R. C.; Fu, H. S.; Deng, X. H.; Zhou, M.; Burch, J. L.; Torbert, R. B.

    2017-08-01

    Electromagnetic ion cyclotron (EMIC) waves can precipitate the ring current ions and relativistic electrons and heat the cold electrons in the magnetosphere. This requires comprehensive knowledge of the occurrence and wave properties of EMIC waves. In the present study, we used the data from one new mission, the Magnetospheric Multiscale (MMS) mission launched in March 2015, to investigate the occurrence and wave properties of H+-band and He+-band EMIC waves in the magnetosphere. Our statistical results show the following: (1) H+-band EMIC waves mostly occur in the higher L-shells (L > 5) while He+-band EMIC waves are mostly observed in the lower L-shells (L < 6). (2) The occurrence rate of H+-band EMIC waves in the dayside is higher than that in the nightside. The highest peak of occurrence rate of H+-band EMIC waves is in the postnoon sector (5-8 L-shells), and the secondary peak lies in the small area of the dawn sector. (3) The wave power spectral density peaks in the postnoon and predusk sectors, while the wave normal angles are largest in the dawn sector. (4) Linear and right-hand polarized H+-band EMIC waves are mainly in the regions of peak occurrence, while linear polarized waves are seen to also dominate outside of the regions of peak occurrence. The highest occurrence rate of linear polarized He+-band EMIC waves is observed in the dawn sector. We discussed the results and compared with previous findings.

  6. Traumatic brain injury and co-occurring problems in prison populations: A systematic review.

    PubMed

    O'Rourke, Conall; Linden, Mark A; Lohan, Maria; Bates-Gaston, Jackie

    2016-01-01

    A growing body of epidemiological research suggests high rates of traumatic brain injury (TBI) in prisoners. The aim of this review is to systematically explore the literature surrounding the rates of TBI and their co-occurrences in a prison population. Six electronic databases were systematically searched for articles published between 1980-2014. Studies were screened for inclusion based on pre-determined criteria by two researchers who independently performed data extraction. Study quality was appraised based on a modified quality assessment tool. Twenty-six studies were included in this review. Quality assessment ranged from 20% (poor) to 80% (good), with an overall average of 60%. Twenty-four papers included TBI prevalence rates, which ranged from 5.69-88%. Seventeen studies explored co-occurring factors including rates of aggression (n = 7), substance abuse (n = 9), anxiety and depression (n = 5), neurocognitive deficits (n = 4) and psychiatric conditions (n = 3). The high degree of variation in TBI rates may be attributed to the inconsistent way in which TBI was measured, with only seven studies using valid and reliable screening tools. Additionally, gaps in the literature surrounding personality outcomes in prisoners with TBI, female prisoners with TBI and qualitative outcomes were found.

  7. Drinking Context and Intimate Partner Violence: Evidence From the California Community Health Study of Couples

    PubMed Central

    Cunradi, Carol B.; Mair, Christina; Todd, Michael; Remer, Lillian

    2012-01-01

    Objective: Couples in which one or both partners is a heavy or problem drinker are at elevated risk for intimate partner violence (IPV), yet little is known about the extent to which each partner’s drinking in different contexts (volume consumed per setting in bars, parties, at home, or in public places) increases the likelihood that partner aggression will occur. This study examined associations between the volume consumed in different settings by each partner and the occurrence and frequency of IPV. Method: We obtained a geographic sample of married or cohabiting couples residing in 50 medium to large California cities. Cross-sectional survey data were collected via confidential telephone interviews (60% response rate). Logistic and negative binomial regression analyses were based on 1,585 couples who provided information about past-12-month IPV, drinking contexts (number of times attended, proportion of drinking occasions when attended, average number of drinks), frequency of intoxication, and psychosocial and demographic factors. Drinking context–IPV associations for each partner were adjusted for the other partner’s volume for that context and other covariates. Results: Male partner’s volume per setting for bars and parks or public places was associated with the occurrence and frequency of male-to-female IPV and female-to-male IPV. Male’s volume per setting for quiet evening at home was associated with the occurrence of female-to-male IPV; female partner’s volume for this setting was associated with the frequency of male-to-female IPV and female-to-male IPV. Conclusions: Among couples in the general population, each partner’s drinking in certain contexts is an independent risk factor for the occurrence and frequency of partner aggression. PMID:22846237

  8. The solar cycle variation of the rates of CMEs and related activity

    NASA Technical Reports Server (NTRS)

    Webb, David F.

    1991-01-01

    Coronal mass ejections (CMEs) are an important aspect of the physics of the corona and heliosphere. This paper presents results of a study of occurrence frequencies of CMEs and related activity tracers over more than a complete solar activity cycle. To properly estimate occurrence rates, observed CME rates must be corrected for instrument duty cycles, detection efficiencies away from the skyplane, mass detection thresholds, and geometrical considerations. These corrections are evaluated using CME data from 1976-1989 obtained with the Skylab, SMM and SOLWIND coronagraphs and the Helios-2 photometers. The major results are: (1) the occurrence rate of CMEs tends to track the activity cycle in both amplitude and phase; (2) the corrected rates from different instruments are reasonably consistent; and (3) over the long term, no one class of solar activity tracer is better correlated with CME rate than any other (with the possible exception of type II bursts).

  9. Influence of environment and climate on occurrence of the cixiid planthopper Hyalesthes obsoletus, the vector of the grapevine disease 'bois noir'.

    PubMed

    Panassiti, Bernd; Breuer, Michael; Marquardt, Stacey; Biedermann, Robert

    2013-12-01

    Species distribution models (SDMs), which are well established in many fields of biological research, are still uncommon in the agricultural risk analysis of pest insects. To exemplify the use of SDMs, we investigated the influence of environmental factors on the occurrence of Hyalesthes obsoletus Signoret (Hemiptera: Cixiidae). The planthopper is the only known vector of the grapevine yellows disease 'bois noir'. The study was conducted in 145 locations in the Baden region of southwest Germany. The planthopper was surveyed on host plant patches, consisting of stinging nettle and/or bindweeds. We used a stratified modelling framework where (1) species presence-absence data were related to an extensive environmental dataset using logistic regressions; and (2) different types of average models were developed based on an information theoretic method. The results show that the incidence of H. obsoletus is associated to above- as well as below-ground environmental factors, particularly to the amount of fine soil and average annual precipitation. This result was consistent across all average models. The relative importance of other environmental variables was dependent upon the average model under consideration and thus may vary according to their intended use, either the explanation of habitat requirements or the prediction and mapping of occurrence risks. The study showed that SDMs offer a quantification of species' habitat requirements and thus, could represent a valuable tool for pest management purposes. By providing examples of current issues of grapevine pests in viticulture, we discuss the use of SDMs in agricultural risk analysis and highlight their advantages and caveats.

  10. Nano- and femtosecond UV laser pulses to immobilize biomolecules onto surfaces with preferential orientation

    NASA Astrophysics Data System (ADS)

    Lettieri, S.; Avitabile, A.; Della Ventura, B.; Funari, R.; Ambrosio, A.; Maddalena, P.; Valadan, M.; Velotta, R.; Altucci, C.

    2014-10-01

    By relying on the photonic immobilization technique of antibodies onto surfaces, we realized portable biosensors for light molecules based on the use of quartz crystal microbalances, given the linear dependence of the method on the laser pulse intensity. Here, we compare the quality of the anchoring method when using nanosecond (260 nm, 25 mJ/pulse, 5 ns, 10 Hz rep. rate) and femtosecond (258 nm, 25 μJ/pulse, 150 fs, 10 kHz rep. rate) laser source, delivering the same energy to the sample with the same average power. As a reference, we also tethered untreated antibodies by means of the passive adsorption. The results are striking: When the antibodies are irradiated with the femtosecond pulses, the deposition on the gold plate is much more ordered than in the other two cases. The effects of UV pulses irradiation onto the antibodies are also analyzed by measuring absorption and fluorescence and suggest the occurrence of remarkable degradation when nanosecond pulses are used likely induced by a larger thermal coupling. In view of the high average power required to activate the antibodies for the achievement of the photonic immobilization technique, we conclude that femtosecond rather than nanosecond laser pulses have to be used.

  11. Does Stress Result in You Exercising Less? Or Does Exercising Result in You Being Less Stressed? Or Is It Both? Testing the Bi-directional Stress-Exercise Association at the Group and Person (N of 1) Level.

    PubMed

    Burg, Matthew M; Schwartz, Joseph E; Kronish, Ian M; Diaz, Keith M; Alcantara, Carmela; Duer-Hefele, Joan; Davidson, Karina W

    2017-12-01

    Psychosocial stress contributes to heart disease in part by adversely affecting maintenance of health behaviors, while exercise can reduce stress. Assessing the bi-directional relationship between stress and exercise has been limited by lack of real-time data and theoretical and statistical models. This lack may hinder efforts to promote exercise maintenance. We test the bi-directional relationship between stress and exercise using real-time data for the average person and the variability-individual differences-in this relationship. An observational study was conducted within a single cohort randomized controlled experiment. Healthy young adults, (n = 79) who reported only intermittent exercise, completed 12 months of stress monitoring by ecological momentary assessment (at the beginning of, end of, and during the day) and continuous activity monitoring by Fitbit. A random coefficients linear mixed model was used to predict end-of-day stress from the occurrence/non-occurrence of exercise that day; a logistic mixed model was used to predict the occurrence/non-occurrence of exercise from ratings of anticipated stress. Separate regression analyses were also performed for each participant. Sensitivity analysis tested all models, restricted to the first 180 days of observation (prior to randomization). We found a significant average inverse (i.e., negative) effect of exercise on stress and of stress on exercise. There was significant between-person variability. Of N = 69, exercise was associated with a stress reduction for 15, a stress increase for 2, and no change for the remainder. We also found that an increase in anticipated stress reported the previous night or that morning was associated with a significant 20-22% decrease (OR = 0.78-0.80) in the odds of exercising that day. Of N = 69, this increase in stress reduced the likelihood of exercise for 17, increased the odds for 1, and had no effect for the remainder. We were unable to identify psychosocial factors that moderate the individual differences in these effects. The relationship of stress to exercise can be uni- or bi-directional and varies from person to person. A precision medicine approach may improve exercise uptake.

  12. 13 CFR 123.3 - How are disaster declarations made?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the disaster occurrence. When a Governor certifies with respect to a drought or to below average water... period meet or exceed the U.S. Drought Monitor (USDM) standard of “severe” (Intensity level D-2 to D-4). The USDM may be found at http://drought.unl.edu/dm/monitor. With respect to below average water levels...

  13. 13 CFR 123.3 - How are disaster declarations made?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the disaster occurrence. When a Governor certifies with respect to a drought or to below average water... period meet or exceed the U.S. Drought Monitor (USDM) standard of “severe” (Intensity level D-2 to D-4). The USDM may be found at http://drought.unl.edu/dm/monitor. With respect to below average water levels...

  14. 13 CFR 123.3 - How are disaster declarations made?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the disaster occurrence. When a Governor certifies with respect to a drought or to below average water... period meet or exceed the U.S. Drought Monitor (USDM) standard of “severe” (Intensity level D-2 to D-4). The USDM may be found at http://drought.unl.edu/dm/monitor. With respect to below average water levels...

  15. 13 CFR 123.3 - How are disaster declarations made?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the disaster occurrence. When a Governor certifies with respect to a drought or to below average water... period meet or exceed the U.S. Drought Monitor (USDM) standard of “severe” (Intensity level D-2 to D-4). The USDM may be found at http://drought.unl.edu/dm/monitor. With respect to below average water levels...

  16. 13 CFR 123.3 - How are disaster declarations made?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the disaster occurrence. When a Governor certifies with respect to a drought or to below average water... period meet or exceed the U.S. Drought Monitor (USDM) standard of “severe” (Intensity level D-2 to D-4). The USDM may be found at http://drought.unl.edu/dm/monitor. With respect to below average water levels...

  17. [Occurrence and survival condition of lung cancer with different histologies among residents in Pudong new area].

    PubMed

    Chen, Hanyi; Yang, Chen; Yan, Bei; Sun, Lianghong; Wu, Zheng; Li, Xiaopan; Zhang, Meiyu; Li, Xiaoli; Yang, Liming

    2014-03-01

    Different histologies of lung cancer vary in occurrence and prognosis. This study aims to analyze the incidence and occurrence trend of lung cancer and investigate the survival rate and its influential factors among lung cancer patients with different histologies. Permanent residents were recruited between 2002 and 2009 in Pudong New Area (former Nanhui Area and former Pudong Area), Shanghai, China. Annual percent changes were estimated by a linear regression of the logarithm on the incidence rates for eight years. Survival rates were calculated and compared by using life-table analysis and Log-rank test, respectively. The standardized incidence rates of lung cancer were 52.28 and 18.86 per 100,000 in males and females, respectively. The median survival time was 410.72 days for specific classified lung cancer. The incidence rates of adenocarcinoma ranked the highest and showed an upward tendency (P<0.05). Patients with small cell lung cancer showed the worst survival condition. The survival condition in males with squamous cell lung cancer living in former Nanhui Area was better compared with those living in former Pudong Area. Lung cancers with different histologies demonstrated different occurrence trends and survival rates. Gender, age, and living area influence the survival rates of lung cancer with different histologies.

  18. Mortality of employees of the Atomic Weapons Establishment, 1951-82.

    PubMed Central

    Beral, V.; Fraser, P.; Carpenter, L.; Booth, M.; Brown, A.; Rose, G.

    1988-01-01

    A total of 22,552 workers employed by the Atomic Weapons Establishment between 1951 and 1982 were followed up for an average of 18.6 years. Of the 3115 who died, 865 (28%) died of cancer. Mortality was 23% lower than the national average for all causes of death and 18% lower for cancer. These low rates were consistent with the findings in other workforces in the nuclear industry and reflect, at least in part, the selection of healthy people to work in the industry and the disproportionate recruitment of people from the higher social classes. At some time during their employment 9389 (42%) of the workers were monitored for exposure to radiation, the average cumulative whole body exposure to external radiation being 7.8 mSv. Their mortality was generally similar to that of other employees, even when exposures were lagged by 10 years. The rate ratio after a 10 year lag in workers with a radiation record compared with other workers was 1.01 (95% confidence interval 0.92 to 1.10) for all causes of death and 1.06 (0.89 to 1.27) for all malignant neoplasms. The only significant differences were for prostatic cancer (rate ratio 2.23; 95% confidence interval 1.13 to 4.40) and for cancers of ill defined and secondary sites (rate ratio 2.37; 1.23 to 4.56). Cancers of lymphatic and haemopoietic tissues were notable for their low occurrence in the study population, with only four deaths from leukaemia and two from multiple myeloma in workers with a radiation record, 9.16 and 3.55 deaths respectively being expected on the basis of national rates. Among workers who had a radiation record 3742 (40%) were also monitored for possible internal exposure to plutonium, 3044 (32%) to uranium, 1562 (17%) to tritium, 638 (7%) to polonium, and 281 (3%) to actinium. In these workers mortality from malignant neoplasms as a whole was not increased, but after a 10 year lag death rates from prostatic and renal cancers were generally more than twice the national average, these excesses arising in a small group of workers monitored for exposure to multiple radionuclides. Though mortality from lung cancer in workers monitored for exposure to plutonium was below the national average, it was some two thirds higher than in other radiation workers, the excess being of borderline statistical significance. Mortality from malignant neoplasms as a whole showed a weak and non-significant increasing trend with increasing level of cumulative whole body exposure to external radiation. When the exposures were lagged by 10 years the trend became stronger and significant, the estimated increase in relative risk per 10 mSv being 7.6% (95% confidence interval 0.4% to 15.3%). This trend was confined almost entirely to workers who were also monitored for exposure to radionuclides (p<0.001), the main contributions coming from lung cancer and prostatic cancer. Exposures of the lung and prostate from internal sources of radiation were not quantified, except for the contribution from tritium. It was therefore not possible to assess the extent to which the associations were due to internally deposited radionuclides rather than external exposure. The finding for prostatic cancer taken in conjunction with the results of other studies suggest a specific occupational hazard in a small group of workers in the nuclear industry who had comparatively high exposures to external radiation and who were also monitored for internal exposure to multiple radionuclides. Research is needed to discover whether any of the radionuclides and other substances concerned are concentrated in the prostate. The occurrence of lung cancer in this workforce requires further investigation taking into account smoking habits and tissue doses from inhaled radionuclides. PMID:3142540

  19. Relationship between road traffic accidents and conflicts recorded by drive recorders.

    PubMed

    Lu, Guangquan; Cheng, Bo; Kuzumaki, Seigo; Mei, Bingsong

    2011-08-01

    Road traffic conflicts can be used to estimate the probability of accident occurrence, assess road safety, or evaluate road safety programs if the relationship between road traffic accidents and conflicts is known. To this end, we propose a model for the relationship between road traffic accidents and conflicts recorded by drive recorders (DRs). DRs were installed in 50 cars in Beijing to collect records of traffic conflicts. Data containing 1366 conflicts were collected in 193 days. The hourly distributions of conflicts and accidents were used to model the relationship between accidents and conflicts. To eliminate time series and base number effects, we defined and used 2 parameters: average annual number of accidents per 10,000 vehicles per hour and average number of conflicts per 10,000 vehicles per hour. A model was developed to describe the relationship between the two parameters. If A(i) = average annual number of accidents per 10,000 vehicles per hour at hour i, and E(i) = average number of conflicts per 10,000 vehicles per hour at hour i, the relationship can be expressed as [Formula in text] (α>0, β>0). The average number of traffic accidents increases as the number of conflicts rises, but the rate of increase decelerates as the number of conflicts increases further. The proposed model can describe the relationship between road traffic accidents and conflicts in a simple manner. According to our analysis, the model fits the present data.

  20. A stability analysis of AVE-4 severe weather soundings

    NASA Technical Reports Server (NTRS)

    Johnson, D. L.

    1982-01-01

    The stability and vertical structure of an average severe storm sounding, consisting of both thermodynamic and wind vertical profiles, were investigated to determine if they could be distinguished from an average lag sounding taken 3 to 6 hours prior to severe weather occurrence. The term average is defined here to indicate the arithmetic mean of a parameter, as a function of altitude, determined from a large number of available observations taken either close to severe weather occurrence, or else more than 3 hours before it occurs. The investigative computations were also done to help determine if a severe storm forecast or index could possibly be used or developed. These mean vertical profiles of thermodynamic and wind parameters as a function of severity of the weather, determined from manually digitized radar (MDR) categories are presented. Profile differences and stability index differences are presented along with the development of the Johnson Lag Index (JLI) which is determined entirely upon environmental vertical parameter differences between conditions 3 hours prior to severe weather, and severe weather itself.

  1. The Mw 7.7 Bhuj earthquake: Global lessons for earthquake hazard in intra-plate regions

    USGS Publications Warehouse

    Schweig, E.; Gomberg, J.; Petersen, M.; Ellis, M.; Bodin, P.; Mayrose, L.; Rastogi, B.K.

    2003-01-01

    The Mw 7.7 Bhuj earthquake occurred in the Kachchh District of the State of Gujarat, India on 26 January 2001, and was one of the most damaging intraplate earthquakes ever recorded. This earthquake is in many ways similar to the three great New Madrid earthquakes that occurred in the central United States in 1811-1812, An Indo-US team is studying the similarities and differences of these sequences in order to learn lessons for earthquake hazard in intraplate regions. Herein we present some preliminary conclusions from that study. Both the Kutch and New Madrid regions have rift type geotectonic setting. In both regions the strain rates are of the order of 10-9/yr and attenuation of seismic waves as inferred from observations of intensity and liquefaction are low. These strain rates predict recurrence intervals for Bhuj or New Madrid sized earthquakes of several thousand years or more. In contrast, intervals estimated from paleoseismic studies and from other independent data are significantly shorter, probably hundreds of years. All these observations together may suggest that earthquakes relax high ambient stresses that are locally concentrated by rheologic heterogeneities, rather than loading by plate-tectonic forces. The latter model generally underlies basic assumptions made in earthquake hazard assessment, that the long-term average rate of energy released by earthquakes is determined by the tectonic loading rate, which thus implies an inherent average periodicity of earthquake occurrence. Interpreting the observations in terms of the former model therefore may require re-examining the basic assumptions of hazard assessment.

  2. Numerical investigation on the implications of spring temperature and discharge rate with respect to the geothermal background in a fault zone

    NASA Astrophysics Data System (ADS)

    Jiang, Zhenjiao; Xu, Tianfu; Mariethoz, Gregoire

    2018-04-01

    Geothermal springs are some of the most obvious indicators of the existence of high-temperature geothermal resources in the subsurface. However, geothermal springs can also occur in areas of low average subsurface temperatures, which makes it difficult to assess exploitable zones. To address this problem, this study quantitatively analyzes the conditions associated with the formation of geothermal springs in fault zones, and numerically investigates the implications that outflow temperature and discharge rate from geothermal springs have on the geothermal background in the subsurface. It is concluded that the temperature of geothermal springs in fault zones is mainly controlled by the recharge rate from the country rock and the hydraulic conductivity in the fault damage zone. Importantly, the topography of the fault trace on the land surface plays an important role in determining the thermal temperature. In fault zones with a permeability higher than 1 mD and a lateral recharge rate from the country rock higher than 1 m3/day, convection plays a dominant role in the heat transport rather than thermal conduction. The geothermal springs do not necessarily occur in the place having an abnormal geothermal background (with the temperature at certain depth exceeding the temperature inferred by the global average continental geothermal gradient of 30 °C/km). Assuming a constant temperature (90 °C here, to represent a normal geothermal background in the subsurface at a depth of 3,000 m), the conditions required for the occurrence of geothermal springs were quantitatively determined.

  3. Use of Self-Expanding Stents for the Treatment of Vertebral Artery Ostial Stenosis: a Single Center Experience

    PubMed Central

    Chung, Sun Young; Choi, Jin Woo; Choi, Byung Se; In, Hyun Sin; Kim, Sun Mi; Choi, Choong Gon; Kim, Sang Joon; Suh, Dae Chul

    2010-01-01

    Objective To evaluate our early experience using self-expanding stents to treat atherosclerotic vertebral artery ostial stenosis (VAOS), with respect to technical feasibility and clinical and imaging follow-up results. Materials and Methods A total of 20 lesions in 20 patients underwent stenting of the VAOS using a self-expanding stent (Precise RX; Cordis Neurovascular, Miami Lakes, FL). Two patients were asymptomatic. We analyzed the technical success rate, causes of technical failure, occurrence of any vascular or neurological event, and the occurrence of any neurological abnormality or in-stent restenosis (ISR) seen on follow-up. The imaging follow-up was performed with Doppler ultrasound (DUS) as a primary screening modality. Results One instance of technical failure was caused by failure of the guidewire passage. The stent diameter was 5 mm, and post-stenting balloon dilatations were necessary in all cases. Stent misplacement requiring placement of an additional stent occurred in four cases. Following a 14.8 month average clinical follow-up time, two patients showed anterior circulation ischemia, which was not attributed to the VAOS we treated. Following a 13.7 month average DUS follow-up, five patients showed a mild degree of diffuse or focal intimal thickening in the stent lumen; however, none of the stenosis showed luminal loss of more than 50% and no stent fracture was noted. Conclusion The use of self-expanding stents for treating VAOS was technically feasible and helped to improve artery patency during our limited follow-up interval. PMID:20191062

  4. Ionospheric irregularities over Bahir Dar, Ethiopia during selected geomagnetic storms

    NASA Astrophysics Data System (ADS)

    Kassa, Tsegaye; Damtie, Baylie

    2017-07-01

    We have analyzed the effect of geomagnetic storms on the occurrence of ionospheric irregularities by considering seven case studies in the period of 2013-2014 over Bahir Dar, Ethiopia (11° N , 38° E). We inferred the irregularity indices from GPS phase fluctuation by computing the median of 1-min rate of change of total electron content (fp) along the ray paths from all satellites observed. The Fp -index was calculated as an hourly average fp -index values along the ray paths from all satellites observed during each hour. Our results revealed that the irregularity level was inhibited during post sunset hours of the main phase of the storms we considered. On average, the irregularity index has dropped from 400 (0.4 TECU/min) during quiet time to 50 (0.05 TECU/min) on disturbed time with an amount of 350 (0.35 TECU/min). However, in some of the cases, immediately after the onset of the storm, we observed the enhancement of irregularities. We found that only the observations on 01 June 2013 and 19 February 2014 exhibited a correspondence of the time of occurrence of the minimum of the Dst-index with inhibition of irregularities noted by other researchers. Our observations of the enhancement of irregularities on 17 March 2013 and 19 February 2014 can partly be explained by the orientation of the IMF BZ . Other measurements such as neutral wind, electric field are required to explain the observations on 29 June 2013, 06 July 2013, 09 November 2013 and 27 February 2014.

  5. Analysis of extreme precipitation characteristics in low mountain areas based on three-dimensional copulas—taking Kuandian County as an example

    NASA Astrophysics Data System (ADS)

    Wang, Cailin; Ren, Xuehui; Li, Ying

    2017-04-01

    We defined the threshold of extreme precipitation using detrended fluctuation analysis based on daily precipitation during 1955-2013 in Kuandian County, Liaoning Province. Three-dimensional copulas were introduced to analyze the characteristics of four extreme precipitation factors: the annual extreme precipitation day, extreme precipitation amount, annual average extreme precipitation intensity, and extreme precipitation rate of contribution. The results show that (1) the threshold is 95.0 mm, extreme precipitation events generally occur 1-2 times a year, the average extreme precipitation intensity is 100-150 mm, and the extreme precipitation amount is 100-270 mm accounting for 10 to 37 % of annual precipitation. (2) The generalized extreme value distribution, extreme value distribution, and generalized Pareto distribution are suitable for fitting the distribution function for each element of extreme precipitation. The Ali-Mikhail-Haq (AMH) copula function reflects the joint characteristics of extreme precipitation factors. (3) The return period of the three types has significant synchronicity, and the joint return period and co-occurrence return period have long delay when the return period of the single factor is long. This reflects the inalienability of extreme precipitation factors. The co-occurrence return period is longer than that of the single factor and joint return period. (4) The single factor fitting only reflects single factor information of extreme precipitation but is unrelated to the relationship between factors. Three-dimensional copulas represent the internal information of extreme precipitation factors and are closer to the actual. The copula function is potentially widely applicable for the multiple factors of extreme precipitation.

  6. Time Correlations of Lightning Flash Sequences in Thunderstorms Revealed by Fractal Analysis

    NASA Astrophysics Data System (ADS)

    Gou, Xueqiang; Chen, Mingli; Zhang, Guangshu

    2018-01-01

    By using the data of lightning detection and ranging system at the Kennedy Space Center, the temporal fractal and correlation of interevent time series of lightning flash sequences in thunderstorms have been investigated with Allan factor (AF), Fano factor (FF), and detrended fluctuation analysis (DFA) methods. AF, FF, and DFA methods are powerful tools to detect the time-scaling structures and correlations in point processes. Totally 40 thunderstorms with distinguishing features of a single-cell storm and apparent increase and decrease in the total flash rate were selected for the analysis. It is found that the time-scaling exponents for AF (αAF) and FF (αFF) analyses are 1.62 and 0.95 in average, respectively, indicating a strong time correlation of the lightning flash sequences. DFA analysis shows that there is a crossover phenomenon—a crossover timescale (τc) ranging from 54 to 195 s with an average of 114 s. The occurrence of a lightning flash in a thunderstorm behaves randomly at timescales <τc but shows strong time correlation at scales >τc. Physically, these may imply that the establishment of an extensive strong electric field necessary for the occurrence of a lightning flash needs a timescale >τc, which behaves strongly time correlated. But the initiation of a lightning flash within a well-established extensive strong electric field may involve the heterogeneities of the electric field at a timescale <τc, which behave randomly.

  7. Inverse relationship between ambient temperature and admissions for diabetic ketoacidosis and hyperglycemic hyperosmolar state: A 14-year time-series analysis.

    PubMed

    Lu, Chin-Li; Chang, Hsin-Hui; Chen, Hua-Fen; Ku, Li-Jung Elizabeth; Chang, Ya-Hui; Shen, Hsiu-Nien; Li, Chung-Yi

    2016-09-01

    This study aimed to investigate the association of admissions for diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) with ambient temperature and season, respectively in patients with diabetes mellitus (DM), after excluding known co-morbidities that predispose onset of acute hyperglycemia events. This was a time series correlation analysis based on medical claims of 40,084 and 33,947 episodes of admission for DKA and HHS, respectively over a 14-year period in Taiwan. These episodes were not accompanied by co-morbidities known to trigger incidence of DKA and HHS. Monthly temperature averaged from 19 meteorological stations across Taiwan was correlated with monthly rate of admission for DKA or HHS, respectively, using the 'seasonal Autoregressive Integrated Moving Average' (seasonal ARIMA) regression method. There was an inverse relationship between ambient temperature and rates of admission for DKA (β=-0.035, p<0.001) and HHS (β=-0.016, p<0.001), despite a clear decline in rates of DKA/HHS admission in the second half of the study period. We also noted that winter was significantly associated with increased rates of both DKA (β=0.364, p<0.001) and HHS (β=0.129, p<0.05) admissions, as compared with summer. On the other hand, fall was associated with a significantly lower rate of HHS admission (β=-0.016, p<0.05). Further stratified analyses according to sex and age yield essentially similar results. It is suggested that meteorological data can be used to raise the awareness of acute hyperglycemic complication risk for both patients with diabetes and clinicians to further avoid the occurrence of DKA and HHS. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Selenium in edible mushrooms.

    PubMed

    Falandysz, Jerzy

    2008-01-01

    Selenium is vital to human health. This article is a compendium of virtually all the published data on total selenium concentrations, its distribution in fruitbody, bioconcentration factors, and chemical forms in wild-grown, cultivated, and selenium-enriched mushrooms worldwide. Of the 190 species reviewed (belonging to 21 families and 56 genera), most are considered edible, and a few selected data relate to inedible mushrooms. Most of edible mushroom species examined until now are selenium-poor (< 1 microg Se/g dry weight). The fruitbody of some species of wild-grown edible mushrooms is naturally rich in selenium; their occurrence data are reviewed, along with information on their suitability as a dietary source of selenium for humans, the impact of cooking and possible leaching out, the significance of traditional mushroom dishes, and the element's absorption rates and co-occurrence with some potentially problematic elements. The Goat's Foot (Albatrellus pes-caprae) with approximately 200 microg Se/g dw on average (maximum up to 370 microg/g dw) is the richest one in this element among the species surveyed. Several other representatives of the genus Albatrellus are also abundant in selenium. Of the most popular edible wild-grown mushrooms, the King Bolete (Boletus edulis) is considered abundant in selenium as well; on average, it contains approximately 20 microg Se/g dw (maximum up to 70 microg/g dw). Some species of the genus Boletus, such as B. pinicola, B. aereus, B. aestivalis, B. erythropus, and B. appendiculus, can also accumulate considerable amounts of selenium. Some other relatively rich sources of selenium include the European Pine Cone Lepidella (Amanita strobiliformis), which contains, on average, approximately 20 microg Se/g dw (up to 37 microg/g dw); the Macrolepiota spp., with an average range of approximately 5 to < 10 microg/g dw (an exception is M. rhacodes with < 10 microg/g dw); and the Lycoperdon spp., with an average of approximately 5 microg Se/g dw. For several wild-grown species of the genus Agaricus, the selenium content ( approximately 5 microg/g dw) is much greater than that from cultivated Champignon Mushroom; these include A. bisporus, A. bitorquis, A. campestris, A. cesarea, A. campestris, A. edulis, A. macrosporus, and A. silvaticus. A particularly rich source of selenium could be obtained from selenium-enriched mushrooms that are cultivated on a substrate fortified with selenium (as inorganic salt or selenized-yeast). The Se-enriched Champignon Mushroom could contain up to 30 or 110 microg Se/g dw, while the Varnished Polypore (Ganoderma lucidum) could contain up to 72 microg Se/g dw. An increasingly growing database on chemical forms of selenium of mushrooms indicates that the seleno-compounds identified in carpophore include selenocysteine, selenomethionine, Se-methylselenocysteine, selenite, and several unidentified seleno-compounds; their proportions vary widely. Some aspects of environmental selenium occurrence and human body pharmacokinetics and nutritional needs will also be briefly discussed in this review.

  9. Characterization of the Temporal Clustering of Flood Events across the Central United States in terms of Climate States

    NASA Astrophysics Data System (ADS)

    Mallakpour, Iman; Villarini, Gabriele; Jones, Michael; Smith, James

    2016-04-01

    The central United States is a region of the country that has been plagued by frequent catastrophic flooding (e.g., flood events of 1993, 2008, 2013, and 2014), with large economic and social repercussions (e.g., fatalities, agricultural losses, flood losses, water quality issues). The goal of this study is to examine whether it is possible to describe the occurrence of flood events at the sub-seasonal scale in terms of variations in the climate system. Daily streamflow time series from 774 USGS stream gage stations over the central United States (defined here to include North Dakota, South Dakota, Nebraska, Kansas, Missouri, Iowa, Minnesota, Wisconsin, Illinois, West Virginia, Kentucky, Ohio, Indiana, and Michigan) with a record of at least 50 years and ending no earlier than 2011 are used for this study. We use a peak-over-threshold (POT) approach to identify flood peaks so that we have, on average two events per year. We model the occurrence/non-occurrence of a flood event over time using regression models based on Cox processes. Cox processes are widely used in biostatistics and can be viewed as a generalization of Poisson processes. Rather than assuming that flood events occur independently of the occurrence of previous events (as in Poisson processes), Cox processes allow us to account for the potential presence of temporal clustering, which manifests itself in an alternation of quiet and active periods. Here we model the occurrence/non-occurrence of flood events using two climate indices as climate time-varying covariates: the North Atlantic Oscillation (NAO) and the Pacific-North American pattern (PNA). The results of this study show that NAO and/or PNA can explain the temporal clustering in flood occurrences in over 90% of the stream gage stations we considered. Analyses of the sensitivity of the results to different average numbers of flood events per year (from one to five) are also performed and lead to the same conclusions. The findings of this work highlight that variations in the climate system play a critical role in explaining the occurrence of flood events at the sub-seasonal scale over the central United States.

  10. Modifying exposure to smoking depicted in movies: a novel approach to preventing adolescent smoking.

    PubMed

    Sargent, James D; Dalton, Madeline A; Heatherton, Todd; Beach, Mike

    2003-07-01

    Most behavioral approaches to adolescent smoking address the behavior directly. We explore an indirect approach: modifying exposure to portrayals of smoking in movies. To describe adolescents' exposure to smoking in movies and to examine factors that could modify such exposure. Occurrences of smoking were counted in each of 601 popular movies. Four thousand nine hundred ten northern New England junior high school students were asked to report which movies they had seen from a randomly generated subsample of 50 films, and responses were used to estimate exposure to the entire sample. Analysis The outcome variable was exposure to movie smoking, defined as the number of smoking occurrences seen. Risk factors for exposure included access to movies (movie channels, videotape use, and movie theater); parenting (R [restricted]-rated movie restrictions, television restrictions, parenting style); and characteristics of the child (age, sex, school performance, sensation-seeking propensity, rebelliousness, and self-esteem). We used multiple regression to assess the association between risk factors and exposure to movie smoking. Subjects had seen an average of 30% of the movie sample (interquartile range, 20%-44%), from which they were exposed to 1160 (interquartile range, 640-1970) occurrences of smoking. In a multivariate model, exposure to movie smoking increased (all P values <.001) by about 10% for each additional movie channel and for every 2 videos watched per week. Exposure increased by 30% for those going to the movie theater more than once per month compared with those who did not go at all. Parent restriction on viewing R-rated movies resulted in a 50% reduction in exposure to movie smoking. There was no association between parenting style and exposure to movie smoking. Much of the protective effect of parent R-rated movie restriction on adolescent smoking was mediated through lower exposure to movie smoking. Adolescents see thousands of smoking depictions in movies, and this influences their attitudes and behavior. Exposure to movie smoking is reduced when parents limit movie access. Teaching parents to monitor and enforce movie access guidelines could reduce adolescent smoking in an indirect, yet powerful, manner.

  11. Multiple paternity and sporophytic inbreeding depression in a dioicous moss species.

    PubMed

    Szövényi, P; Ricca, M; Shaw, A J

    2009-11-01

    Multiple paternity (polyandry) frequently occurs in flowering plants and animals and is assumed to have an important function in the evolution of reproductive traits. Polyandry in bryophytes may occur among multiple sporophytes of a female gametophyte; however, its occurrence and extent is unknown. In this study we investigate the occurrence and extent of multiple paternity, spatial genetic structure, and sporophytic inbreeding depression in natural populations of a dioicous bryophyte species, Sphagnum lescurii, using microsatellite markers. Multiple paternity is prevalent among sporophytes of a female gametophyte and male genotypes exhibit significant skew in paternity. Despite significant spatial genetic structure in the population, suggesting frequent inbreeding, the number of inbred and outbred sporophytes was balanced, resulting in an average fixation coefficient and population level selfing rate of zero. In line with the prediction of sporophytic inbreeding depression sporophyte size was significantly correlated with the level of heterozygosity. Furthermore, female gametophytes preferentially supported sporophytes with higher heterozygosity. These results indicate that polyandry provides the opportunity for postfertilization selection in bryophytes having short fertilization distances and spatially structured populations facilitating inbreeding. Preferential maternal support of the more heterozygous sporophytes suggests active inbreeding avoidance that may have significant implications for mating system evolution in bryophytes.

  12. Occurrence, composition and ecological restoration of organic pollutants in water environment of South Canal, China

    NASA Astrophysics Data System (ADS)

    Wang, Y. Z.; Lin, C.; Zhou, X. S.; Zhang, Y.; Han, C. G.

    2017-08-01

    Ecological restoration of polluted river water was carried out in South Canal by adding microbial water purifying agents and biological compound enzymes. The objective of present study was to investigate the ecological restoration effect of organic pollutants by this efficient immobilized microbial technologies, analysis the occurrence and composition of organic pollutants including fifteen persistent organochlorine pesticides (OCPs), seventeen polycyclic aromatic hydrocarbons (PAHs) and eighteen organophosphorus pesticides (OPPs) both in natural water environment and ecological restoration area of South Canal, China. Results showed that the total concentrations of OCPs ranged from 1.11 to 1.78 ng·L-1, PAHs from 52.76 to 60.28 ng·L-1, and OPPs from 6.51 to 17.50 ng·L-1. Microbial water purifying agents and biological compound enzymes essentially had no effects on biological degradation of OCPs and PAHs in the river, but could remove OPPs with degradation rates ranging from 19.6% to 62.8% (35.2% in average). Degradation mechanisms of microbial water purifying agents and biological compound enzymes on OCPs, PAHs and OPPs remained to be further studied. This technology has a certain value in practical ecological restoration of organic pollutants in rivers and lakes.

  13. Case-Control Study of Injury Intervention for Preschool Children in Henggang, Shenzhen.

    PubMed

    Wang, Hong; Liu, Yi-Xin; Deng, Wen-Jiao; Yang, Wei-Jian; Wang, Fang

    2015-10-01

    To explore effective interventions for child accidental injury prevention and to reduce the incidence of injury. Cluster random sampling method was adopted, and children in 19 kindergartens in Henggang, Shenzhen and their parents were selected as the objects of study. Nineteen kindergartens were randomly divided into intervention group and control group to carry out the injury intervention case-control study. Through a series of interventions, there were certain effects. After the end of the project, the injury incidence rates of the intervention group and the control group were 4.91%, 10.64%, and the difference was significant; the average costs of treatment for injuries of the intervention group and the control group were 168.4 Yuan and 206.8 Yuan, and the difference was statistically significant; compared with before the implementation of the project, the rate of various types of injuries after the end of the project declined, in which, the rate of mechanical injury, pet bites, accidental falls, burns, and traffic accidents decreased significantly. The differences were significant. Injury interventions can effectively prevent and control the occurrence of injury.

  14. Identifying seizure clusters in patients with psychogenic nonepileptic seizures.

    PubMed

    Baird, Grayson L; Harlow, Lisa L; Machan, Jason T; Thomas, Dave; LaFrance, W C

    2017-08-01

    The present study explored how seizure clusters may be defined for those with psychogenic nonepileptic seizures (PNES), a topic for which there is a paucity of literature. The sample was drawn from a multisite randomized clinical trial for PNES; seizure data are from participants' seizure diaries. Three possible cluster definitions were examined: 1) common clinical definition, where ≥3 seizures in a day is considered a cluster, along with two novel statistical definitions, where ≥3 seizures in a day are considered a cluster if the observed number of seizures statistically exceeds what would be expected relative to a patient's: 1) average seizure rate prior to the trial, 2) observed seizure rate for the previous seven days. Prevalence of clusters was 62-68% depending on cluster definition used, and occurrence rate of clusters was 6-19% depending on cluster definition. Based on these data, clusters seem to be common in patients with PNES, and more research is needed to identify if clusters are related to triggers and outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Giant Planet Occurrence Rate as a Function of Stellar Mass

    NASA Astrophysics Data System (ADS)

    Reffert, Sabine; Bergmann, Christoph; Quirrenbach, Andreas; Trifonov, Trifon; Künstler, Andreas

    2013-07-01

    For over 12 years we have carried out a Doppler survey at Lick Observatory, identifying 15 planets and 20 candidate planets in a sample of 373 G and K giant stars. We investigate giant planet occurrence rate as a function of stellar mass and metallicity in this sample, which covers the mass range from about 1 to 3.5-5.0 solar masses. We confirm the presence of a strong planet-metallicity correlation in our giant star sample, which is fully consistent with the well-known planet-metallicity correlation for main-sequence stars. Furthermore, we find a very strong dependence of the giant planet occurrence rate on stellar mass, which we fit with a gaussian distribution. Stars with masses of about 1.9 solar masses have the highest probability of hosting a giant planet, whereas the planet occurrence rate drops rapidly for masses larger than 2.5 to 3.0 solar masses. We do not find any planets around stars more massive than 2.7 solar masses, although we have 113 stars with masses between 2.7 and 5.0 solar masses in our sample (planet occurrence rate in that mass range: 0% +1.6% at 68.3% confidence). This result is not due to a bias related to planet detectability as a function of stellar mass. We conclude that larger mass stars do not form giant planets which are observable at orbital distances of a few AU today. Possible reasons include slower growth rate due to the snow-line being located further out, longer migration timescale and faster disk depletion.

  16. Invasive Cancer Incidence, 2004-2013, and Deaths, 2006-2015, in Nonmetropolitan and Metropolitan Counties - United States.

    PubMed

    Henley, S Jane; Anderson, Robert N; Thomas, Cheryll C; Massetti, Greta M; Peaker, Brandy; Richardson, Lisa C

    2017-07-07

    Previous reports have shown that persons living in nonmetropolitan (rural or urban) areas in the United States have higher death rates from all cancers combined than persons living in metropolitan areas. Disparities might vary by cancer type and between occurrence and death from the disease. This report provides a comprehensive assessment of cancer incidence and deaths by cancer type in nonmetropolitan and metropolitan counties. 2004-2015. Cancer incidence data from CDC's National Program of Cancer Registries and the National Cancer Institute's Surveillance, Epidemiology, and End Results program were used to calculate average annual age-adjusted incidence rates for 2009-2013 and trends in annual age-adjusted incidence rates for 2004-2013. Cancer mortality data from the National Vital Statistics System were used to calculate average annual age-adjusted death rates for 2011-2015 and trends in annual age-adjusted death rates for 2006-2015. For 5-year average annual rates, counties were classified into four categories (nonmetropolitan rural, nonmetropolitan urban, metropolitan with population <1 million, and metropolitan with population ≥1 million). For the trend analysis, which used annual rates, these categories were combined into two categories (nonmetropolitan and metropolitan). Rates by county classification were examined by sex, age, race/ethnicity, U.S. census region, and cancer site. Trends in rates were examined by county classification and cancer site. During the most recent 5-year period for which data were available, nonmetropolitan rural areas had lower average annual age-adjusted cancer incidence rates for all anatomic cancer sites combined but higher death rates than metropolitan areas. During 2006-2015, the annual age-adjusted death rates for all cancer sites combined decreased at a slower pace in nonmetropolitan areas (-1.0% per year) than in metropolitan areas (-1.6% per year), increasing the differences in these rates. In contrast, annual age-adjusted incidence rates for all cancer sites combined decreased approximately 1% per year during 2004-2013 both in nonmetropolitan and metropolitan counties. This report provides the first comprehensive description of cancer incidence and mortality in nonmetropolitan and metropolitan counties in the United States. Nonmetropolitan rural counties had higher incidence of and deaths from several cancers related to tobacco use and cancers that can be prevented by screening. Differences between nonmetropolitan and metropolitan counties in cancer incidence might reflect differences in risk factors such as cigarette smoking, obesity, and physical inactivity, whereas differences in cancer death rates might reflect disparities in access to health care and timely diagnosis and treatment. Many cancer cases and deaths could be prevented, and public health programs can use evidence-based strategies from the U.S. Preventive Services Task Force and Advisory Committee for Immunization Practices (ACIP) to support cancer prevention and control. The U.S. Preventive Services Task Force recommends population-based screening for colorectal, female breast, and cervical cancers among adults at average risk for these cancers and for lung cancer among adults at high risk; screening adults for tobacco use and excessive alcohol use, offering counseling and interventions as needed; and using low-dose aspirin to prevent colorectal cancer among adults considered to be at high risk for cardiovascular disease based on specific criteria. ACIP recommends vaccination against cancer-related infectious diseases including human papillomavirus and hepatitis B virus. The Guide to Community Preventive Services describes program and policy interventions proven to increase cancer screening and vaccination rates and to prevent tobacco use, excessive alcohol use, obesity, and physical inactivity.

  17. Potential breeding distributions of U.S. birds predicted with both short-term variability and long-term average climate data.

    PubMed

    Bateman, Brooke L; Pidgeon, Anna M; Radeloff, Volker C; Flather, Curtis H; VanDerWal, Jeremy; Akçakaya, H Resit; Thogmartin, Wayne E; Albright, Thomas P; Vavrus, Stephen J; Heglund, Patricia J

    2016-12-01

    Climate conditions, such as temperature or precipitation, averaged over several decades strongly affect species distributions, as evidenced by experimental results and a plethora of models demonstrating statistical relations between species occurrences and long-term climate averages. However, long-term averages can conceal climate changes that have occurred in recent decades and may not capture actual species occurrence well because the distributions of species, especially at the edges of their range, are typically dynamic and may respond strongly to short-term climate variability. Our goal here was to test whether bird occurrence models can be predicted by either covariates based on short-term climate variability or on long-term climate averages. We parameterized species distribution models (SDMs) based on either short-term variability or long-term average climate covariates for 320 bird species in the conterminous USA and tested whether any life-history trait-based guilds were particularly sensitive to short-term conditions. Models including short-term climate variability performed well based on their cross-validated area-under-the-curve AUC score (0.85), as did models based on long-term climate averages (0.84). Similarly, both models performed well compared to independent presence/absence data from the North American Breeding Bird Survey (independent AUC of 0.89 and 0.90, respectively). However, models based on short-term variability covariates more accurately classified true absences for most species (73% of true absences classified within the lowest quarter of environmental suitability vs. 68%). In addition, they have the advantage that they can reveal the dynamic relationship between species and their environment because they capture the spatial fluctuations of species potential breeding distributions. With this information, we can identify which species and guilds are sensitive to climate variability, identify sites of high conservation value where climate variability is low, and assess how species' potential distributions may have already shifted due recent climate change. However, long-term climate averages require less data and processing time and may be more readily available for some areas of interest. Where data on short-term climate variability are not available, long-term climate information is a sufficient predictor of species distributions in many cases. However, short-term climate variability data may provide information not captured with long-term climate data for use in SDMs. © 2016 by the Ecological Society of America.

  18. Does garbage in the diet improve reproductive output of Glaucous Gulls

    USGS Publications Warehouse

    Weiser, E.L.; Powell, A.N.

    2010-01-01

    Anthropogenic subsidies are used by a variety of predators in areas developed for human use or residence. If subsidies promote population growth, these predators can have a negative effect on local prey species. The Glaucous Gull (Larus hyperboreus) is an abundant predator in northern Alaska that is believed to benefit from garbage as a supplemental food source, but this supposition has never been tested. In summer 2008 and 2009, we recorded the Glaucous Gull's diet and reproduction at 10 breeding colonies in northern Alaska. Colonies were in industrial, residential, and undeveloped areas and ranged from 5 to 75 km from the nearest landfill. By colony, garbage occurred in zero to 85% of pellets and food remains produced during the chick-rearing period, and the average number of chicks fledged per pair ranged from zero to 2.9. Random-forest analysis indicated that percent occurrence of garbage in the diet was the second most important factor (after number of eggs per pair) explaining variance in fledging rate. There was a significant positive correlation between percent occurrence of garbage in the diet and fledging rate in each year. If this correlation reflects a causal relationship, it suggests that human development that increases gulls' access to garbage could result in increased local gull populations. Such an increase could affect the gulls' natural prey species, including at least 14 species of shorebirds and waterfowl of conservation concern. ?? The Cooper Ornithological Society 2010.

  19. QBO/solar modulation of the boreal winter Madden-Julian oscillation: A prediction for the coming solar minimum

    NASA Astrophysics Data System (ADS)

    Hood, Lon L.

    2017-04-01

    The Madden-Julian oscillation (MJO), also known as the 30-60 day oscillation, is the strongest of the intraseasonal climate oscillations in the tropics and has significant derivative effects on extratropical circulation and intraseasonal climate. It has recently been shown that the stratospheric quasi-biennial oscillation (QBO) modulates the amplitude of the boreal winter MJO such that MJO amplitudes are larger on average during the easterly phase (QBOE) than during the westerly phase (QBOW). A major possible mechanism is the decrease in static stability in the lowermost stratosphere under QBOE conditions resulting from relative upwelling associated with the QBO-induced meridional circulation. Here evidence is presented that tropical upwelling changes related to the 11 year solar cycle also modulate the boreal winter MJO. Based on 37.3 years of MJO amplitude data, the largest amplitudes and occurrence rates, and the weakest static stabilities in the tropical lower stratosphere, occur during the QBOE phase under solar minimum (SMIN) conditions while the smallest amplitudes and strongest static stabilities occur during the QBOW phase under solar maximum (SMAX) conditions. Conversely, when the QBO and solar forcings are opposed (QBOW/SMIN and QBOE/SMAX), the difference in occurrence rates becomes statistically insignificant. During the coming solar minimum, at least one additional winter in the QBOE/SMIN category should occur (possibly as early as 2017/2018) during which especially large MJO amplitudes are expected and an initial test of these results will be possible.

  20. Low-Frequency Plasma Waves in Saturn's Magnetosphere: A Comprehensive Analysis of Magnetometer Data from the Cassini Era (2004-2017)

    NASA Astrophysics Data System (ADS)

    Meeks, Z. C.; Simon, S.; Kabanovic, S.; Liuzzo, L.

    2017-12-01

    Based on all available Cassini magnetic field data sets collected between 2004 and 2017, we construct a three-dimensional map of ion cyclotron waves (ICWs) in the Saturnian magnetosphere. First, we survey the magnetometer data for ICWs, which can be applied to constrain the local ion production rate, as well as the mass of the newly-generated ions. We find that the occurrence rate of ion cyclotron waves decreases according to a Fermi-Dirac-like profile w.r.t. radial distance, with only few waves observed beyond the orbit of Rhea. In the north-south direction, the ICW amplitude decreases non-linearly with no waves occurring farther than two Saturnian radii from the equatorial plane. The ICWs are generated in a narrow band (extension 0.3 Saturn radii) around the planet's equatorial plane and then propagate away from the magnetic equator in both hemispheres. We derive an analytical expression for the three-dimensional shape of the region populated by ICWs. We also analyze the distribution of mirror mode waves in Saturn's equatorial magnetosphere. We find that this wave mode occurs independent of Local Time. In radial direction, we identify a transition region between L=5.5 and L=6.5 where a drastic drop of ion cyclotron wave occurrence is juxtaposed with the emergence of the mirror mode wave. On average, the dilute atmospheres around Dione and Rhea have no statistically significant impact on either the ICWs or the mirror mode waves. We then apply hybrid (kinetic ions, fluid electrons) modeling to study the generation of ion cyclotron waves (ICWs) in Saturn's equatorial magnetosphere and to convert the observed ICW amplitudes into a profile of the local ion production rate. Previously, this conversion has been done exclusively at the orbit of Enceladus (Cowee et al. (2009)), but we expand this survey to the complete occurrence realm of ion cyclotron waves in Saturn's equatorial magnetosphere (between L=3.5 and L=9.5). In doing so, we provide a relationship between the observed ion cyclotron wave amplitude and ion production rate between the orbits of Enceladus and Rhea, which we use to characterize the sources of plasma in the Saturnian system.

  1. Relationships between climate, soil moisture and phenology of the woody cover in two sites located along the West African latitudinal gradient

    NASA Astrophysics Data System (ADS)

    Seghieri, Josiane; Vescovo, Aude; Padel, Karine; Soubie, Remy; Arjounin, Marc; Boulain, Nicolas; de Rosnay, Patricia; Galle, Sylvie; Gosset, Marielle; Mouctar, Abakar H.; Peugeot, Christophe; Timouk, Franck

    2009-08-01

    SummaryThe study quantifies the relationships at local scale between phenology and determinants of climate and soil water resources at two sites located along the latitudinal gradient of West Africa, one in the central Sahel (Mali), the other in the Sudanian bioclimatic zone (Benin). The aim is to improve our knowledge on possible vegetation response to possible climate change. Within the Sudanian site, average annual rainfall is 1200 mm, extending from April to October, while, in the Sahelian site, it is 370 mm, occurring from June to September. Physical data were collected from the African Monsoon Multidisciplinary Analysis research programme. The phenology of the dominant species was monitored in four types of vegetation cover at the wetter site, and in three types of vegetation cover at the drier site. For each sampled plant, leafing, flowering and fruiting were recorded as binary variables in terms of the presence/absence of phenophases. A small proportion of the variability of each phenophase occurrence is explained by the logit models. However, rainfall rise is significantly linked to leafing probability increase in the Sahelian site but not in the Sudanian site. Day length extension and temperature decrease are significantly correlated with an increase in leafing in the Sudanian site, but not in the Sahelian. On both sites, the increase in cumulative rainfall is not found to be linked to an increased probability of reproductive phenophases (negative or non-significant relationships). Air temperature is positively correlated with flowering rate in the Sudanian site, but, all other factors being constant, no climate factors are found to be highly significant of flowering occurrence in the Sahel. Fruiting probability is positively correlated mainly with temperature within the Sahelian site. Leafing occurrence is positively correlated with soil moisture in the 0-1 m layer for the Sudanian site, but not for the Sahelian site. Significant relationships between fruiting occurrence and soil moisture may reflect a prior selection of plants on fruiting period that maximizes seed dispersion and germination differently at the two sites. While vegetative and reproduction schedules may be determined by specific genetic factors, the physical environment controls the possibility of their expression. Reduction of the rainfall amount and intensity may increase reproduction rates in wet areas. Although this factor should decrease leafing rate, it does not influence reproduction at dry sites, except through the decrease in air humidity. In wetter areas, increasing temperature may reduce leafing, but may increase reproduction rates. Cover reduction may have an impact on local physical factors and, consequently, probably also affects vegetation phenology.

  2. An anomalous Pt-Pd occurrence below the JM reef, Stillwater Complex, Montana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McIlveen, C.L.

    1993-04-01

    The late Archean Stillwater Complex, in south-central Montana, consists of the Basal, Ultramafic, and Banded series. The Lower Banded series contains several anomalous platinum-group element (PGE) occurrences, with the JM reef having the highest values (an average of 6,250 ppb Pt and 24,000 ppb Pd) and greatest lateral persistence. The Coors anomaly, below the reef, is near the middle of the complex. This zone contains bronzite cumulates which range from 100--14,600 ppb Pt, with an average of 1,250 ppb. Pt:Pd ratios in the Coors zone average 1:1.7, compared to 1:3.8 in the reef. Sulfides associated with the PGE's show immisciblemore » textures indicating a magmatic origin similar to the reef. The anomaly lies approximately 200 m below the reef along the Banded-Ultramafic series contact where the Gabbronorite 1 zone is virtually absent. Layering between the reef and the Ultramafic series bronzitite is irregular and thin compared to the normal 400-m thickness exposed elsewhere in the complex. Bronzitites which contain the PGE's are podiform and often pegmatoidal. Norites adjacent to the bronzities also tend to be pegmatoidal and sulfide-bearing, but contain an average of only 75 ppb Pt. Microprobe analyses of bronzites in this zone show abruptly lower Mg/(Mg + Fe) of 0.77 compared to 0.83 in the uppermost bronzitite. The disrupted layering and thinning in the Coors area may have formed by slumping, scouring, or thermal erosion in the cumulate pile during crystallization. Coors mineralization may have developed through processes similar to those in the JM reef. However, occurrence of the coors mineralization with irregular layering and higher PGE ratios suggest an origin different than that in the reef.« less

  3. Static versus dynamic fracturing in shallow carbonate fault zones

    NASA Astrophysics Data System (ADS)

    Fondriest, M.; Doan, M. L.; Aben, F. M.; Fusseis, F.; Mitchell, T. M.; Di Toro, G.

    2015-12-01

    Moderate to large earthquakes often nucleate within and propagate through carbonates in the shallow crust, therefore several field and experimental studies were recently aimed to constrain earthquake-related deformation processes within carbonate fault rocks. In particular, the occurrence of thick belts (10-100s m) of low-strain fault-related breccias (average size of rock fragments >1 cm), which is relatively common within carbonate damage zones, was generally interpreted as resulting from the quasi-static growth of fault zones rather than from the cumulative effect of multiple earthquake ruptures. Here we report the occurrence of up to hundreds of meters thick belts of intensely fragmented dolostones along the major transpressive Foiana Fault Zone (Italian Southern Alps) which was exhumed from < 2 km depth. Such dolostones are reduced into fragments ranging from few centimeters down to few millimeters in size with ultrafine-grained layers in proximity to the principal slip zones. Preservation of the original bedding indicates a lack of significant shear strain in the fragmented dolostones which seem to have been shattered in situ. To investigate the origin of the in-situ shattered rocks, the host dolostones were deformed in uniaxial compression both under quasi-static loading (strain rate ~10-3 s-1) and dynamic loading (strain rate >50 s-1). Dolostones deformed up to failure under low-strain rate were affected by single to multiple discrete (i.e. not interconnected) extensional fractures sub-parallel to the loading direction. Dolostones deformed under high-strain rate were shattered above a strain rate threshold of ~200 s-1(strain >1.2%) while they were split in few fragments or were macroscopically intact for lower strain rates. Experimentally shattered dolostones were reduced into a non-cohesive material with most rock fragments a few millimeters in size and elongated parallel to the loading direction. Fracture networks were investigated by X-ray microtomography showing that low- and high-strain rate damage patterns are different with the latter being similar to that of natural in-situ shattered dolostones. In-situ shattered dolostones are thus interpreted as the product of off-fault dynamic stress wave loading and can potentially be used to constrain coseismic energy release in fault zones.

  4. Development of Chinese reference man deformable surface phantom and its application to the influence of physique on electromagnetic dosimetry

    NASA Astrophysics Data System (ADS)

    Yu, D.; Wang, M.; Liu, Q.

    2015-09-01

    A reference man is a theoretical individual that represents the average anatomical structure and physiological and metabolic features of a specific group of people and has been widely used in radiation safety research. With the help of an advantage in deformation, the present work proposed a Chinese reference man adult-male polygon-mesh surface phantom based on the Visible Chinese Human segment image dataset by surface rendering and deforming. To investigate the influence of physique on electromagnetic dosimetry in humans, a series of human phantoms with 10th, 50th and 90th body mass index and body circumference percentile physiques for Chinese adult males were further constructed by deforming the Chinese reference man surface phantom. All the surface phantoms were then voxelized to perform electromagnetic field simulation in a frequency range of 20 MHz to 3 GHz using the finite-difference time-domain method and evaluate the whole-body average and organ average specific absorption rate and the ratios of absorbed energy in skin, fat and muscle to the whole body. The results indicate thinner physique leads to higher WBSAR and the volume of subcutaneous fat, the penetration depth of the electromagnetic field in tissues and standing-wave occurrence may be the influence factors of physique on electromagnetic dosimetry.

  5. [Application of central lymph node dissection to surgical operation for clinical stage n0 papillary thyroid carcinoma].

    PubMed

    Hu, Wei; Shi, Jun-Yi; Sheng, Yuan; Ll, Li

    2008-03-01

    The treatment for papillary thyroid carcinoma (PTC) without cervical lymph node metastasis (cN0) is controversial. This study was to explore a suitable method to dissect cervical lymph nodes for stage cN0 PTC patients. Eighty-four stage cN0 PTC patients, diagnosed by B ultrasound or cervical MRI from 2005--2006, were randomly divided into two groups. Thyroidectomy and ipsilateral central lymph node dissection were performed in Group A, while only thyroidectomy was performed in Group B. Each group contained 42 patients. Both groups took thyroxin tablets after operation. An average of 3 lymph nodes were found in each case of Group A, and the lymph node metastasis rate was 47.62%. The occurrence rates of complications were not significantly different between the two groups (P<0.05). Thyroidectomy plus ipsilateral central lymph node dissection is recommended for the treatment of stage cN0 PTC. It can also avoid damage of recurrent laryngeal nerve in re-dissection.

  6. Acute pesticide poisoning among children in South Korea: findings from National Health Insurance claims data, 2006-2009.

    PubMed

    Lee, Won Jin; Ko, Yousun; Cha, Eun Shil

    2014-02-01

    The aim of this study was to estimate the incidence of acute pesticide poisoning among children in South Korea and describe the related epidemiologic characteristics. We evaluated the age-standardized rates of incidence of pesticide poisoning among children in South Korea from 2006 through 2009 using National Health Insurance claims data. A total of 1232 children aged 0-14 years were identified from the acute pesticide poisoning cases reported across South Korea during the study period. The annual average age-standardized rate of incidence from acute pesticide poisoning was 3.6 per 100 000. The majority of the cases were identified in the categories of the 1-4-year-old age-group (56.5%), outpatients (80.0%), single-day visit to a hospital (70.4%) and summer occurrence (43.3%). Acute pesticide poisoning is prevalent among children in South Korea; therefore, intervention efforts are needed to reduce the cases of pesticide poisoning among children.

  7. Forearm vasodilatation following release of venous congestion

    PubMed Central

    Caro, C. G.; Foley, T. H.; Sudlow, M. F.

    1970-01-01

    1. The volume rate of forearm blood flow was measured with a mercury-in-rubber strain gauge, or with a water-filled plethysmograph, from 1 sec after termination of a 2-3 min period of venous congestion. 2. When congesting pressure had been less than 18 mm Hg, average post-congestion flow (five subjects) was constant during approx. 10 sec and not significantly different from resting flow. 3. When congesting pressure had been 30 mm Hg, average post-congestion flow (eight subjects) was 26% higher than resting, during 3-4 sec after release of congestion, but rose to 273% of resting during 4-6 sec after release of congestion. 4. In other studies forearm vascular resistance had been found normal or increased during such venous congestion, and theoretical studies here indicated that passive mechanical factors could not account for the delayed occurrence of high post-congestion flow. 5. It appears, therefore, that the forearm vascular bed dilates actively shortly after release of substantial venous congestion. It would seem more likely that a myogenic mechanism, rather than a metabolic one, is responsible. PMID:5532541

  8. Properties of the Second Outburst of the Bursting Pulsar (GRO J1744-28) as Observed with BATSE

    NASA Technical Reports Server (NTRS)

    Woods, P.; Kouveliotou, C.; vanParadijs, J.; Briggs, M. S.; Wilson, C. A.; Deal, K. J.; Harmon, B. A.; Fishman, G. J.; Lewin, W. H.; Kommers, J.

    1998-01-01

    One year after its discovery, the Bursting Pulsar (GRO J1744-28) went into outburst again, displaying the hard X-ray bursts and pulsations that make this source unique. We report on Burst and Transient Source Experiment (BATSE) observations of both the persistent and burst emission for this second outburst and draw comparisons to the first. The second outburst was smaller than the first in both duration and peak luminosity. The persistent flux, burst peak flux and burst fluence were all reduced in amplitude by a factor approximately 1.7. Despite these differences, the average burst occurrence rate and average burst durations were roughly the same through each outburst. Similar to the first outburst, no spectral evolution was found within bursts and the parameter alpha was very small at the start of the outburst (alpha = 2.1 +/- 1.7 on 1996 December 2). Although no spectral evolution was found within individual bursts, we find evidence for a small (20%) variation of the spectral temperature during the course of the second outburst.

  9. FIRES: Fire Information Retrieval and Evaluation System - A program for fire danger rating analysis

    Treesearch

    Patricia L. Andrews; Larry S. Bradshaw

    1997-01-01

    A computer program, FIRES: Fire Information Retrieval and Evaluation System, provides methods for evaluating the performance of fire danger rating indexes. The relationship between fire danger indexes and historical fire occurrence and size is examined through logistic regression and percentiles. Historical seasonal trends of fire danger and fire occurrence can be...

  10. Climatology of contribution-weighted tropical rain rates based on TRMM 3B42

    NASA Astrophysics Data System (ADS)

    Venugopal, V.; Wallace, J. M.

    2016-10-01

    The climatology of annual mean tropical rain rate is investigated based on merged Tropical Rainfall Measuring Mission (TRMM) 3B42 data. At 0.25° × 0.25° spatial resolution, and 3-hourly temporal resolution, half the rain is concentrated within only ˜1% of the area of the tropics at any given instant. When plotted as a function of logarithm of rain rate, the cumulative contribution of rate-ranked rain occurrences to the annual mean rainfall in each grid box is S shaped and its derivative, the contribution-weighted rain rate spectrum, is Gaussian shaped. The 50% intercept of the cumulative contribution R50 is almost equivalent to the contribution-weighted mean logarithmic rain rate RL¯ based on all significant rain occurrences. The spatial patterns of R50 and RL¯ are similar to those obtained by mapping the fraction of the annual accumulation explained by rain occurrences with rates above various specified thresholds. The geographical distribution of R50 confirms the existence of patterns noted in prior analyses based on TRMM precipitation radar data and reveals several previously unnoticed features.

  11. Anxiety, depression, and PTSD following cardiac arrest: a systematic review of the literature.

    PubMed

    Wilder Schaaf, Kathryn P; Artman, Laura K; Peberdy, Mary Ann; Walker, William C; Ornato, Joseph P; Gossip, Michelle R; Kreutzer, Jeffrey S

    2013-07-01

    Identify the occurrence rate of post-arrest psychological distress; evaluate methodological approaches; suggest future research priorities; address clinical implications. The electronic databases PubMed/MEDLINE and PsychInfo/APA PsycNET were utilized to search for terms including 'Cardiac Arrest', 'Therapeutic Hypothermia' and 'Depression', 'Anxiety', 'Quality of Life', 'Posttraumatic Stress Disorder (PTSD)', 'Psychological Outcomes', 'Hospital Anxiety and Depression Scale (HADS)', and 'Beck Depression Inventory (BDI)'. High rates of psychological distress have been reported after OHCA. Specifically, incidence rates of depression have ranged from 14% to 45%; anxiety rates have ranged from 13% to 61%; PTSD rates reportedly range from 19% to 27%. Variability between studies is likely attributable to methodological variations relating to measures used, time since arrest, and research setting. Given the occurrence rate of psychological distress after OHCA, psychological screening and early intervention seems indicated in the cardiac arrest population. Further studies are needed to better establish occurrence rates in both inpatient and outpatient settings, determine appropriate measures and normative cut off scores, and decide on the most appropriate method of intervention. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  12. Observation of classroom social communication: do children with fetal alcohol spectrum disorders spend their time differently than their typically developing peers?

    PubMed

    Olswang, Lesley B; Svensson, Liselotte; Astley, Susan

    2010-12-01

    In this research, the authors examined how social communication profiles during classroom activities differed between children with fetal alcohol spectrum disorders (FASD) and typically developing pair-matched peers. Twelve pairs of children were observed in their classrooms 20 min a day for 4 days across 2 weeks. Coders documented classroom social communication by recording performance on handheld computers using the Social Communication Coding System (L. B. Olswang, L. Svensson, T. E. Coggins, J. Beilinson, & A. L. Donaldson, 2006). The Social Communication Coding System consists of 6 behavioral dimensions (prosocial/engaged, passive/disengaged, irrelevant, hostile/coercive, assertive, and adult seeking) that account for all verbal and nonverbal productions during a specified timeframe. The frequency of occurrence and duration of each dimension (as measured by proportion of time and average length of time spent performing each dimension) were recorded. Children with FASD had significantly more occurrences of passive/disengaged and irrelevant behavior, and the proportion and average length of time in these behaviors were larger and longer than those of their peers. Further, children with FASD had significantly more occurrences of prosocial/engaged behavior; however, the proportion and average length of time that they spent being prosocial were smaller and shorter than those of their peers. Implications Results suggest children with mild FASD performed differently than their peers in regard to classroom social communication, which was consistent with parent and teacher behavioral reports.

  13. Occurrence of carboxylic acids in different steps of two drinking-water treatment plants using different disinfectants.

    PubMed

    Jurado-Sánchez, Beatriz; Ballesteros, Evaristo; Gallego, Mercedes

    2014-03-15

    The occurrence of 35 aliphatic and aromatic carboxylic acids within two full scale drinking-water treatment plants was evaluated for the first time in this research. At the intake of each plant (raw water), the occurrence of carboxylic acids varied according to the quality of the water source although in both cases 13 acids were detected at average concentrations of 6.9 and 4.7 μg/L (in winter). In the following steps in each treatment plant, the concentration patterns of these compounds differed depending on the type of disinfectant applied. Thus, after disinfection by chloramination, the levels of the acids remained almost constant (average concentration, 6.3 μg/L) and four new acids were formed (butyric, 2-methylbutyric, 3-hydroxybenzoic and 2-nitrobenzoic) at low levels (1.1-5 μg/L). When ozonation/chlorination was used, the total concentration of the carboxylic acids in the raw water sample (4.7 μg/L) increased up to 6 times (average concentration, 26.3 μg/L) after disinfection and 6 new acids (mainly aromatic) were produced at high levels (3.5-100 μg/L). Seasonal variations of the carboxylic acids under study showed that in both plants, maximum levels of all the analytes were reached in the coldest months (autumn and winter), aromatic acids only being found in those seasons. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Multiplets: Their behavior and utility at dacitic and andesitic volcanic centers

    USGS Publications Warehouse

    Thelen, W.; Malone, S.; West, M.

    2011-01-01

    Multiplets, or groups of earthquakes with similar waveforms, are commonly observed at volcanoes, particularly those exhibiting unrest. Using triggered seismic data from the 1980-1986 Mount St. Helens (MSH) eruption, we have constructed a catalog of multiplet occurrence. Our analysis reveals that the occurrence of multiplets is related, at least in part, to the viscosity of the magma. We also constructed catalogs of multiplet occurrence using continuous seismic data from the 2004 eruption at MSH and 2007 eruption at Bezymianny Volcano, Russia. Prior to explosions at MSH in 2004 and Bezymianny in 2007, the multiplet proportion of total seismicity (MPTS) declined, while the average amplitudes and standard deviations of the average amplitude increased. The life spans of multiplets (time between the first and last event) were also shorter prior to explosions than during passive lava extrusion. Dome-forming eruptions that include a partially solidified plug, like MSH (1983-1986 and 2004-2008), often possess multiplets with longer life spans and MPTS values exceeding 50%. Conceptually, the relatively unstable environment prior to explosions is characterized by large and variable stress gradients brought about by rapidly changing overpressures within the conduit. We infer that such complex stress fields affect the number of concurrent families, MPTS, average amplitude, and standard deviation of the amplitude of the multiplets. We also argue that multiplet detection may be an important new monitoring tool for determining the timing of explosions and in forecasting the type of eruption.

  15. Occurrence of heterotrophic and coliform bacteria in liquid hand soaps from bulk refillable dispensers in public facilities.

    PubMed

    Chattman, Marisa; Gerba, Sheri L; Maxwell, Charles P

    2011-03-01

    The goal of the study discussed in this article was to determine the occurrence of heterotrophic and coliform bacteria in liquid soap from bulk refillable dispensers, obtained from restrooms in a variety of public facilities. A total of 541 samples was collected from five U.S. cities. Liquid soap from dispensers in public areas was found to contain heterotrophic and coliform bacterial numbers averaging more than 106 CFU/mL in 24.8% of the dispensers.

  16. The value of time-averaged serum high-sensitivity C-reactive protein in prediction of mortality and dropout in peritoneal dialysis patients.

    PubMed

    Liu, Shou-Hsuan; Chen, Chao-Yu; Li, Yi-Jung; Wu, Hsin-Hsu; Lin, Chan-Yu; Chen, Yung-Chang; Chang, Ming-Yang; Hsu, Hsiang-Hao; Ku, Cheng-Lung; Tian, Ya-Chung

    2017-01-01

    C-reactive protein (CRP) is a useful biomarker for prediction of long-term outcomes in patients undergoing chronic dialysis. This observational cohort study evaluated whether the time-averaged serum high-sensitivity CRP (HS-CRP) level was a better predictor of clinical outcomes than a single HS-CRP level in patients undergoing peritoneal dialysis (PD). We classified 335 patients into three tertiles according to the time-averaged serum HS-CRP level and followed up regularly from January 2010 to December 2014. Clinical outcomes such as cardiovascular events, infection episodes, newly developed malignancy, encapsulating peritoneal sclerosis (EPS), dropout (death plus conversion to hemodialysis), and mortality were assessed. During a 5-year follow-up, 164 patients (49.0%) ceased PD; this included 52 patient deaths (15.5%), 100 patients (29.9%) who converted to hemodialysis, and 12 patients (3.6%) who received a kidney transplantation. The Kaplan-Meier survival analysis and log-rank test revealed a significantly worse survival accumulation in patients with high time-average HS-CRP levels. A multivariate Cox regression analysis revealed that a higher time-averaged serum HS-CRP level, older age, and the occurrence of cardiovascular events were independent mortality predictors. A higher time-averaged serum HS-CRP level, the occurrence of cardiovascular events, infection episodes, and EPS were important predictors of dropout. The receiver operating characteristic analysis verified that the value of the time-average HS-CRP level in predicting the 5-year mortality and dropout was superior to a single serum baseline HS-CRP level. This study shows that the time-averaged serum HS-CRP level is a better marker than a single baseline measurement in predicting the 5-year mortality and dropout in PD patients.

  17. Influence of stellar multiplicity on planet formation. II. Planets are less common in multiple-star systems with separations smaller than 1500 AU

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Ji; Fischer, Debra A.; Xie, Ji-Wei

    2014-08-20

    Almost half of the stellar systems in the solar neighborhood are made up of multiple stars. In multiple-star systems, planet formation is under the dynamical influence of stellar companions, and the planet occurrence rate is expected to be different from that of single stars. There have been numerous studies on the planet occurrence rate of single star systems. However, to fully understand planet formation, the planet occurrence rate in multiple-star systems needs to be addressed. In this work, we infer the planet occurrence rate in multiple-star systems by measuring the stellar multiplicity rate for planet host stars. For a subsamplemore » of 56 Kepler planet host stars, we use adaptive optics (AO) imaging and the radial velocity (RV) technique to search for stellar companions. The combination of these two techniques results in high search completeness for stellar companions. We detect 59 visual stellar companions to 25 planet host stars with AO data. Three stellar companions are within 2'' and 27 within 6''. We also detect two possible stellar companions (KOI 5 and KOI 69) showing long-term RV acceleration. After correcting for a bias against planet detection in multiple-star systems due to flux contamination, we find that planet formation is suppressed in multiple-star systems with separations smaller than 1500 AU. Specifically, we find that compared to single star systems, planets in multiple-star systems occur 4.5 ± 3.2, 2.6 ± 1.0, and 1.7 ± 0.5 times less frequently when a stellar companion is present at a distance of 10, 100, and 1000 AU, respectively. This conclusion applies only to circumstellar planets; the planet occurrence rate for circumbinary planets requires further investigation.« less

  18. Sporadic emission of ultra high energy gamma rays from Crab pulsar

    NASA Astrophysics Data System (ADS)

    Bhat, P. N.; Gupta, S. K.; Ramana Murthy, P. V.; Sreekantan, B. V.; Tonwar, S. C.; Vishwanath, P. R.

    A 24 hr emission variability of the Crab pulsar was examined. The data were gathered in the energy range up to 500 GeV using the Oota Atmospheric Cerenkov array. Analysis proceeded in terms of one second curves with retention of only those data within 5 sigma of the nominal values. The mean time between events was about 125 msec, while some microbursts occurred at a rate of one per 0.5 msec and could happen twice within a minute (macroburst). A coincidence of pulse occurrence and phase was noted. Phasograms were generated for the events coming from the Crab pulsar, which displayed peak emissions for only 0.0001 of the observing time. It is concluded that traditional averaging analysis can mask periods of intense emissions.

  19. Mass loss at Saturn: The contribution of plasmoids

    NASA Astrophysics Data System (ADS)

    Kivelson, M.; Jia, X.; Jackman, C. M.

    2017-12-01

    Jia and Kivelson (2012) showed that an MHD simulation of Saturn's magnetosphere including rotating field-aligned currents generates a plasmoid on each rotation period. For southern summer conditions, plasmoids form through reconnection in the tail near midnight at a rotation phase for which the core magnetic field perturbation points towards the planet in the LT sector of the release. After release, they move northward and outward in the post midnight sector. Mass loss is found to be dominated by plasmoid release, and to compare closely to the mass source rate; much of the outward mass flux is found in the 0300-0900 LT sector. However, studies of plasmoid signatures in Cassini magnetometer data conclude that releases do not occur each rotation period and infer mass loss rates far smaller than Saturn's mass source rate (Jackman et al., 2014). Studies based on plasma data also infer loss rates smaller than the source rate from Enceladus (Thomsen, 2013). The simulation suggests that plasmoid occurrence frequency depends strongly on local time and latitude. Indeed, in regions near the equator and near midnight, where plasmoids are present in the simulation, the occurrence frequency of plasmoid releases inferred from magnetometer data is higher than elsewhere (Jackman et al., 2016; Smith et al., 2016), with occurrence probability peaking at the phase predicted by the simulation. We consider how the observational limitations should be modified to establish mass loss rates and plasmoid occurrence frequency.

  20. Orogen-scale uplift in the central Italian Apennines drives episodic behaviour of earthquake faults

    PubMed Central

    Cowie, P. A.; Phillips, R. J.; Roberts, G. P.; McCaffrey, K.; Zijerveld, L. J. J.; Gregory, L. C.; Faure Walker, J.; Wedmore, L. N. J.; Dunai, T. J.; Binnie, S. A.; Freeman, S. P. H. T.; Wilcken, K.; Shanks, R. P.; Huismans, R. S.; Papanikolaou, I.; Michetti, A. M.; Wilkinson, M.

    2017-01-01

    Many areas of the Earth’s crust deform by distributed extensional faulting and complex fault interactions are often observed. Geodetic data generally indicate a simpler picture of continuum deformation over decades but relating this behaviour to earthquake occurrence over centuries, given numerous potentially active faults, remains a global problem in hazard assessment. We address this challenge for an array of seismogenic faults in the central Italian Apennines, where crustal extension and devastating earthquakes occur in response to regional surface uplift. We constrain fault slip-rates since ~18 ka using variations in cosmogenic 36Cl measured on bedrock scarps, mapped using LiDAR and ground penetrating radar, and compare these rates to those inferred from geodesy. The 36Cl data reveal that individual faults typically accumulate meters of displacement relatively rapidly over several thousand years, separated by similar length time intervals when slip-rates are much lower, and activity shifts between faults across strike. Our rates agree with continuum deformation rates when averaged over long spatial or temporal scales (104 yr; 102 km) but over shorter timescales most of the deformation may be accommodated by <30% of the across-strike fault array. We attribute the shifts in activity to temporal variations in the mechanical work of faulting. PMID:28322311

  1. Is There a CME Rate Floor? CME and Magnetic Flux Values for the Last Four Solar Cycle Minima

    NASA Astrophysics Data System (ADS)

    Webb, D. F.; Howard, R. A.; St. Cyr, O. C.; Vourlidas, A.

    2017-12-01

    The recent prolonged activity minimum has led to the question of whether there is a base level of the solar magnetic field evolution that yields a “floor” in activity levels and also in the solar wind magnetic field strength. Recently, a flux transport model coupled with magneto-frictional simulations has been used to simulate the continuous magnetic field evolution in the global solar corona for over 15 years, from 1996 to 2012. Flux rope eruptions in the simulations are estimated (Yeates), and the results are in remarkable agreement with the shape of the SOlar Heliospheric Observatory/Large Angle and Spectrometric Coronagraph Experiment coronal mass ejection (CME) rate distribution. The eruption rates at the two recent minima approximate the observed-corrected CME rates, supporting the idea of a base level of solar magnetic activity. In this paper, we address this issue by comparing annual averages of the CME occurrence rates during the last four solar cycle minima with several tracers of the global solar magnetic field. We conclude that CME activity never ceases during a cycle, but maintains a base level of 1 CME every 1.5 to ∼3 days during minima. We discuss the sources of these CMEs.

  2. Orogen-scale uplift in the central Italian Apennines drives episodic behaviour of earthquake faults.

    PubMed

    Cowie, P A; Phillips, R J; Roberts, G P; McCaffrey, K; Zijerveld, L J J; Gregory, L C; Faure Walker, J; Wedmore, L N J; Dunai, T J; Binnie, S A; Freeman, S P H T; Wilcken, K; Shanks, R P; Huismans, R S; Papanikolaou, I; Michetti, A M; Wilkinson, M

    2017-03-21

    Many areas of the Earth's crust deform by distributed extensional faulting and complex fault interactions are often observed. Geodetic data generally indicate a simpler picture of continuum deformation over decades but relating this behaviour to earthquake occurrence over centuries, given numerous potentially active faults, remains a global problem in hazard assessment. We address this challenge for an array of seismogenic faults in the central Italian Apennines, where crustal extension and devastating earthquakes occur in response to regional surface uplift. We constrain fault slip-rates since ~18 ka using variations in cosmogenic 36 Cl measured on bedrock scarps, mapped using LiDAR and ground penetrating radar, and compare these rates to those inferred from geodesy. The 36 Cl data reveal that individual faults typically accumulate meters of displacement relatively rapidly over several thousand years, separated by similar length time intervals when slip-rates are much lower, and activity shifts between faults across strike. Our rates agree with continuum deformation rates when averaged over long spatial or temporal scales (10 4  yr; 10 2  km) but over shorter timescales most of the deformation may be accommodated by <30% of the across-strike fault array. We attribute the shifts in activity to temporal variations in the mechanical work of faulting.

  3. Exposure to daily ambient particulate polycyclic aromatic hydrocarbons and cough occurrence in adult chronic cough patients: A longitudinal study

    NASA Astrophysics Data System (ADS)

    Anyenda, Enoch Olando; Higashi, Tomomi; Kambayashi, Yasuhiro; Thao, Nguyen Thi Thu; Michigami, Yoshimasa; Fujimura, Masaki; Hara, Johsuke; Tsujiguchi, Hiromasa; Kitaoka, Masami; Asakura, Hiroki; Hori, Daisuke; Yamada, Yohei; Hayashi, Koichiro; Hayakawa, Kazuichi; Nakamura, Hiroyuki

    2016-09-01

    The specific components of airborne particulates responsible for adverse health effects have not been conclusively identified. We conducted a longitudinal study on 88 adult patients with chronic cough to evaluate whether exposure to daily ambient levels of particulate polycyclic aromatic hydrocarbons (PAH) has relationship with cough occurrence. Study participants were recruited at Kanazawa University Hospital, Japan and were physician-diagnosed to at least have asthma, cough variant asthma and/or atopic cough during 4th January to 30th June 2011. Daily cough symptoms were collected by use of cough diaries and simultaneously, particulate PAH content in daily total suspended particles collected on glass fiber filters were determined by high performance liquid chromatography coupled with fluorescence detector. Population averaged estimates of association between PAH exposure and cough occurrence for entire patients and subgroups according to doctor's diagnosis were performed using generalized estimating equations. Selected adjusted odds ratios for cough occurrence were 1.088 (95% confidence interval (CI): 1.031, 1.147); 1.209 (95% CI: 1.060, 1.379) per 1 ng/m3 increase for 2-day lag and 6-day moving average PAH exposure respectively. Likewise, 5 ring PAH had higher odds in comparison to 4 ring PAH. On the basis of doctor's diagnosis, non-asthma group had slightly higher odds ratio 1.127 (95% CI: 1.033, 1.228) per 1 ng/m3 increase in 2-day lag PAH exposure. Our findings suggest that ambient PAH exposure is associated with cough occurrence in adult chronic cough patients. The association may be stronger in non-asthma patients and even at low levels although there is need for further study with a larger sample size of respective diagnosis and inclusion of co-pollutants.

  4. The global landslide distribution in the 2015-16 El Nino event

    NASA Astrophysics Data System (ADS)

    Petley, D. N.; Froude, M.

    2016-12-01

    It is commonly perceived that the global landslide distribution is heavily influenced by the El Nino / La Nina cycle, and that strong El Nino events are associated with a higher than average occurrence of landslides in many areas. Thus, for example, the very intense 1997-98 El Nino event coincided with high incidence of landslides in parts of North America and South America, and elsewhere. However, there is comparatively little systematic analysis on a global basis. The 2015-16 El Nino event was the most intense since 1997-98, and had been anticipated to generate significant landslide impacts. The occurrence of landslides worldwide through the 2015-16 El Nino has been examined using the author's landslide fatality database, which has been compiled since 2002. The data indicates that 2015 was a year with an unusually small number of rainfall-induced landslides, significantly below the long term average and with unusually low consequences. This is primarily because of two key factors: first, the South Asian monsoon was anomalously weak, resulting in low landslide impacts in the Himalayas. Second, the occurrence of intense landfalling tropical cyclones across East Asia was also unusually low. The combined effect of these two sets of meteorological conditions was low landslide occurrence across Asia. Landslide occurrence across the Americas was also low. On the other hand, 2016 is proving to be an unusually intense landslide year. In particular, intense rainfall associated with early part of the South Asian monsoon has resulted in very widespread landsliding across South Asia. This paper examines the lessons that can be learnt from an improved understanding the relationship between El Nino events and global landslide impacts, and reflects upon the capability to anticipate the impacts of future large El Nino events.

  5. Anthrax and the geochemistry of soils in the contiguous United States

    USGS Publications Warehouse

    Griffin, Dale W.; Silvestri, Erin E.; Bowling, Charlena Y.; Boe, Timothy; Smith, David B.; Nichols, Tonya L.

    2014-01-01

    Soil geochemical data from sample sites in counties that reported occurrences of anthrax in wildlife and livestock since 2000 were evaluated against counties within the same states (MN, MT, ND, NV, OR, SD and TX) that did not report occurrences. These data identified the elements, calcium (Ca), manganese (Mn), phosphorus (P) and strontium (Sr), as having statistically significant differences in concentrations between county type (anthrax occurrence versus no occurrence). Tentative threshold values of the lowest concentrations of each of these elements (Ca = 0.43 wt %, Mn = 142 mg/kg, P = 180 mg/kg and Sr = 51 mg/kg) and average concentrations (Ca = 1.3 wt %, Mn = 463 mg/kg, P = 580 mg/kg and Sr = 170 mg/kg) were identified from anthrax-positive counties as prospective investigative tools in determining whether an outbreak had “potential” or was “likely” at any given geographic location in the contiguous United States.

  6. Stability and Occurrence Rate Constraints on the Planetary Sculpting Hypothesis for “Transitional” Disks

    NASA Astrophysics Data System (ADS)

    Dong, Ruobing; Dawson, Rebekah

    2016-07-01

    Transitional disks, protoplanetary disks with deep and wide central gaps, may be the result of planetary sculpting. By comparing numerical planet-opening-gap models with observed gaps, we find systems of 3-6 giant planets are needed in order to open gaps with the observed depths and widths. We explore the dynamical stability of such multi-planet systems using N-body simulations that incorporate prescriptions for gas effects. We find they can be stable over a typical disk lifetime, with the help of eccentricity damping from the residual gap gas that facilitates planets locking into mean motion resonances. However, in order to account for the occurrence rate of transitional disks, the planet sculpting scenario demands gap-opening-friendly disk conditions, in particular, a disk viscosity α ≲ 0.001. In addition, the demography of giant planets at ˜3-30 au separations, poorly constrained by current data, has to largely follow occurrence rates extrapolated outward from radial velocity surveys, not the lower occurrence rates extrapolated inward from direct imaging surveys. Even with the most optimistic occurrence rates, transitional disks cannot be a common phase that most gas disks experience at the end of their life, as popularly assumed, simply because there are not enough planets to open these gaps. Finally, as consequences of demanding almost all giant planets at large separations participate in transitional disk sculpting, the majority of such planets must form early and end up in a chain of mean motion resonances at the end of disk lifetime.

  7. Climatology of successive equatorial plasma bubbles observed by GPS ROTI over Malaysia

    NASA Astrophysics Data System (ADS)

    Buhari, S. M.; Abdullah, M.; Yokoyama, T.; Otsuka, Y.; Nishioka, M.; Hasbi, A. M.; Bahari, S. A.; Tsugawa, T.

    2017-02-01

    The occurrence rate of the equatorial plasma bubble (EPB) with season, solar activity, and geomagnetic conditions are investigated using long-term data sets of Malaysia Real-Time Kinematics Network (MyRTKnet) from 2008 to 2013. The rate of TEC (total electron content) change index (ROTI) in 5 min was derived from MyRTKnet data to detect the EPB with scale sizes around tens of kilometers. Then, the daily east-west cross sections of 2-D ROTI maps were used to examine the EPB features over 100°E-119°E longitudes. The EPBs tend to occur successively in one night along the observational coverage of MyRTKnet during equinoxes in high solar activity years. The perturbations in a form of wavelike structures along the observed longitudes might be responsible for the development of successive EPBs due to high growth rate of the Rayleigh-Taylor instability (RTI) process. On the contrary, the occurrence of successive EPBs is infrequent and the occurrence day of EPB remains active during equinoctial months in low solar activity years. The small growth rate of the RTI process during low solar activity years might require a strong seed perturbation to generate the EPB structure. The occurrence probability of the EPB was found to be similar during quiet and disturbed geomagnetic conditions. The results imply that the strong perturbations play an important role in the development of the EPB in low solar activity years. Nonetheless, the high growth rate of the RTI could cause the successive occurrence of the EPB in high solar activity years.

  8. Clostridium difficile infection after colorectal surgery: a rare but costly complication.

    PubMed

    Damle, Rachelle N; Cherng, Nicole B; Flahive, Julie M; Davids, Jennifer S; Maykel, Justin A; Sturrock, Paul R; Sweeney, W Brian; Alavi, Karim

    2014-10-01

    The incidence and virulence of Clostridium difficile infection (CDI) are on the rise. The characteristics of patients who develop CDI following colorectal resection have been infrequently studied. We utilized the University HealthSystem Consortium database to identify adult patients undergoing colorectal surgery between 2008 and 2012. We examined the patient-related risk factors for CDI and 30-day outcomes related to its occurrence. A total of 84,648 patients met our inclusion criteria, of which the average age was 60 years and 50% were female. CDI occurred in 1,266 (1.5%) patients during the years under study. The strongest predictors of CDI were emergent procedure, inflammatory bowel disease (IBD), and major/extreme APR-DRG severity of illness score. CDI was associated with a higher rate of complications, intensive care unit (ICU) admission, longer preoperative inpatient stay, 30-day readmission rate, and death within 30 days compared to non-CDI patients. Cost of the index stay was, on average, $14,130 higher for CDI patients compared with non-CDI patients. Emergent procedures, higher severity of illness, and inflammatory bowel disease are significant risk factors for postoperative CDI in patients undergoing colorectal surgery. Once established, CDI is associated with worse outcomes and higher costs. The poor outcomes of these patients and increased costs highlight the importance of prevention strategies targeting high-risk patients.

  9. Multiple neoplasms among cervical cancer patients in the material of the lower Silesian cancer registry.

    PubMed

    Izmajłowicz, Barbara; Kornafel, Jan; Błaszczyk, Jerzy

    2014-01-01

    According to the definition by the International Agency for Research on Cancer (IARC), primary multiple neoplasms are two or more neoplasms of different histopathological build in one organ, or two or more tumors occurring in one patient, regardless of the time of their occurrence (synchronic - up to 6 months, metachronous - after 6 months), coming from an organ or a tissue and not being an infiltration from another neoplasm, a relapse or a metastasis. It was the aim of the study to analyze the frequency of the occurrence of multiple neoplasms among patients suffering from uterine cervix cancer, with a special interest in coexistent neoplasms, the time of their occurrence and total 5-year survivals. The data from the Lower Silesian Cancer Registry concerning the years 1984-2009 formed the material of the present study. 5.3% of all cervix neoplasms occurred as multiple cancers. Cervix neoplasms were 13.4% of multiple neoplasms. On average, cervical cancer occurred as a subsequent cancer in 6 patients yearly (60.7% of the occurrences of cervical cancer were in the period of 5 years following treatment for the first neoplasm). 5-year survival in patients suffering from primarily multiple cervix neoplasms constituted 57% and was convergent with the results for all patients suffering from cervical cancer. Cervical cancer as the first neoplasm occurred in 287 patients, on average in 11 patients annually. In the period of the first 5 years after the treatment of cervical cancer, there were 42.8% occurrences of other cancers. Cervical neoplasms most frequently coexisted with cancers of the breast, lung and large intestine. The frequency of the occurrence of multiple neoplasm among cervical cancer patients is increasing. Most frequently they coexist with other tobacco-related neoplasms, those related to HPV infections and with secondary post-radiation neoplasms. These facts should be taken into consideration during post-treatment observation and when directing diagnostic and prophylactic tests. Synchronic neoplasms require detailed diagnostics and planning of treatment by a team of specialists. The occurrence of primary multiple cervical neoplasms does not worsen the prognosis as compared to patients suffering exclusively from cervical cancer.

  10. A statistical analysis of equatorial plasma bubble structures based on an all-sky airglow imager network in China

    NASA Astrophysics Data System (ADS)

    Sun, Longchang; Xu, Jiyao; Wang, Wenbin; Yuan, Wei; Li, Qinzeng; Jiang, Chaowei

    2016-11-01

    This paper investigates the statistical features of equatorial plasma bubbles (EPBs) using airglow images from 2012 to 2014 from a ground-based network of four imagers in the equatorial region of China. It is found that (1) EPBs mainly occur during 21:00-00:00 local time (LT) in equinoxes. There is an asymmetry in occurrence rates between March (June) and September equinoxes (December solstices). (2) Most EPBs occur in groups of two to six depletions. The distance between adjacent EPB depletions is 100-700 km, and the average is 200-300 km. The zonal extension of an EPB group is usually less than 1500 km but can reach 3000 km. (3) EPBs usually have a maximum drift velocity near 100 m/s at 21:00-22:00 LT in 9.5° ± 1.5° geomagnetic latitude and then decrease to 50-70 m/s toward sunrise. (4) The averaged westward tilt angle of most EPBs (with respect to the geographic north-south) increased from 5°-10° to 23°-30° with LT between 20:00 and 03:00 LT, then decreasing to 10°-20° toward sunrise. (5) When 90 < F10.7 < 140, the maximum magnetic latitudinal extension (PMLE) is usually lower than 15.0° (apex height 725 km), but it can reach 23.0° (apex height 1330 km) when F10.7 > 140. The maximum PMLE increases by 3.4°-5.5° when F10.7 changes from 90 to 190. (6) The EPB occurrence patterns and zonal drift velocities are significantly different from those at Kolhapur, India, which locates west to our stations by 20.0°-32.0° in longitude.

  11. Seismic sample areas defined from incomplete catalogues: an application to the Italian territory

    NASA Astrophysics Data System (ADS)

    Mulargia, F.; Tinti, S.

    1985-11-01

    The comprehensive understanding of earthquake source-physics under real conditions requires the study not of single faults as separate entities but rather of a seismically active region as a whole, accounting for the interaction among different structures. We define "seismic sample area" the most convenient region to be used as a natural laboratory for the study of seismic source physics. This coincides with the region where the average large magnitude seismicity is the highest. To this end, time and space future distributions of large earthquakes are to be estimated. Using catalog seismicity as an input, the rate of occurrence is not constant but appears generally biased by incompleteness in some parts of the catalog and possible nonstationarities in seismic activity. We present a statistical procedure which is capable, under a few mild assumptions, of both detecting nonstationarities in seismicity and finding the incomplete parts of a seismic catalog. The procedure is based on Kolmogorov-Smirnov nonparametric statistics, and can be applied without a priori assuming the parent distribution of the events. The efficiency of this procedure allows the analysis of small data sets. An application to the Italian territory is presented, using the most recent version of the ENEL seismic catalog. Seismic activity takes place in six well defined areas but only five of them have a number of events sufficient for analysis. Barring a few exceptions, seismicity is found stationary throughout the whole catalog span 1000-1980. The eastern Alps region stands out as the best "sample area", with the highest average probability of event occurrence per time and area unit. Final objective of this characterization is to stimulate a program of intensified research.

  12. Decreased N2O reduction by low soil pH causes high N2O emissions in a riparian ecosystem.

    PubMed

    Van den Heuvel, R N; Bakker, S E; Jetten, M S M; Hefting, M M

    2011-05-01

    Quantification of harmful nitrous oxide (N(2)O) emissions from soils is essential for mitigation measures. An important N(2)O producing and reducing process in soils is denitrification, which shows deceased rates at low pH. No clear relationship between N(2)O emissions and soil pH has yet been established because also the relative contribution of N(2)O as the denitrification end product decreases with pH. Our aim was to show the net effect of soil pH on N(2)O production and emission. Therefore, experiments were designed to investigate the effects of pH on NO(3)(-) reduction, N(2)O production and reduction and N(2) production in incubations with pH values set between 4 and 7. Furthermore, field measurements of soil pH and N(2)O emissions were carried out. In incubations, NO(3)(-) reduction and N(2) production rates increased with pH and net N(2)O production rate was highest at pH 5. N(2)O reduction to N(2) was halted until NO(3)(-) was depleted at low pH values, resulting in a built up of N(2)O. As a consequence, N(2)O:N(2) production ratio decreased exponentially with pH. N(2)O reduction appeared therefore more important than N(2)O production in explaining net N(2)O production rates. In the field, a negative exponential relationship for soil pH against N(2)O emissions was observed. Soil pH could therefore be used as a predictive tool for average N(2)O emissions in the studied ecosystem. The occurrence of low pH spots may explain N(2)O emission hotspot occurrence. Future studies should focus on the mechanism behind small scale soil pH variability and the effect of manipulating the pH of soils. © 2011 Blackwell Publishing Ltd.

  13. A novel symptom cluster analysis among ambulatory HIV/AIDS patients in Uganda.

    PubMed

    Namisango, Eve; Harding, Richard; Katabira, Elly T; Siegert, Richard J; Powell, Richard A; Atuhaire, Leonard; Moens, Katrien; Taylor, Steve

    2015-01-01

    Symptom clusters are gaining importance given HIV/AIDS patients experience multiple, concurrent symptoms. This study aimed to: determine clusters of patients with similar symptom combinations; describe symptom combinations distinguishing the clusters; and evaluate the clusters regarding patient socio-demographic, disease and treatment characteristics, quality of life (QOL) and functional performance. This was a cross-sectional study of 302 adult HIV/AIDS outpatients consecutively recruited at two teaching and referral hospitals in Uganda. Socio-demographic and seven-day period symptom prevalence and distress data were self-reported using the Memorial Symptom Assessment Schedule. QOL was assessed using the Medical Outcome Scale and functional performance using the Karnofsky Performance Scale. Symptom clusters were established using hierarchical cluster analysis with squared Euclidean distances using Ward's clustering methods based on symptom occurrence. Analysis of variance compared clusters on mean QOL and functional performance scores. Patient subgroups were categorised based on symptom occurrence rates. Five symptom occurrence clusters were identified: Cluster 1 (n=107), high-low for sensory discomfort and eating difficulties symptoms; Cluster 2 (n=47), high-low for psycho-gastrointestinal symptoms; Cluster 3 (n=71), high for pain and sensory disturbance symptoms; Cluster 4 (n=35), all high for general HIV/AIDS symptoms; and Cluster 5 (n=48), all low for mood-cognitive symptoms. The all high occurrence cluster was associated with worst functional status, poorest QOL scores and highest symptom-associated distress. Use of antiretroviral therapy was associated with all high symptom occurrence rate (Fisher's exact=4, P<0.001). CD4 count group below 200 was associated with the all high occurrence rate symptom cluster (Fisher's exact=41, P<0.001). Symptom clusters have a differential, affect HIV/AIDS patients' self-reported outcomes, with the subgroup experiencing high-symptom occurrence rates having a higher risk of poorer outcomes. Identification of symptom clusters could provide insights into commonly co-occurring symptoms that should be jointly targeted for management in patients with multiple complaints.

  14. Glove perforation rate in open lung surgery.

    PubMed

    Hollaus, P H; Lax, F; Janakiev, D; Wurnig, P N; Pridun, N S

    1999-04-01

    In open lung surgery the surgical access is encircled by the ribs, which should result in a high glove perforation rate compared with other surgical specialities. Prospectively the surgeon, first and second assistant and the scrub nurse wore double standard latex gloves during 100 thoracotomies. Parameters recorded were: procedure performed, number of perforations, localization of perforation, the seniority of the surgeon, manoeuvre performed at the moment of perforation, immediate cause of perforation, operation time, performance of rib resection during thoracotomy and time of occurrence of the first three perforations. One thousand, six hundred and seventy-three gloves (902 outer, 771 inner) were tested. In 78 operations perforations occurred. There were 150 outer glove perforations (8.9%, 0-8, mean 1.23), 19 inner glove perforations (1.13%, 0-2, mean 0.19). Cutaneous blood exposure was prevented in 78% of all operations and in 87% of all perforations. The perforation rate for the surgeon, the scrub nurse, the first and the second assistant were 61.2, 40.4, 9.7 and 3.1% of all operations, respectively. Rib resection and a duration of more than 2 h resulted in a significant rise of glove perforation rate (P<0.05). The personal experience of the surgeon and the type of operation did not correlate with glove perforation. The immediate cause leading to perforation was named in only 17 cases (13.7%) and comprised contact with bone (seven), a needle stitch (seven) and a production flaw (three). Leaks were localized mostly on the first finger (18%),second finger, (39%) palm and dorsum of the hand (16%). The average occurrence of all first perforations was 38.7 min (range 3-190) after the beginning of surgery, the second after 63.2 min (range 10-195). Fifty-four first perforations (50.5%) were found during the first 30 min of the operation. The reported perforation rate of 78% lies in the highest range of reported perforation rates in different surgical specialities. Double gloving effectively prevented cutaneous blood exposure and thus should become a routine for the thoracic surgeon to prevent transmission of infectious diseases from the patient to the surgeon.

  15. Temporal slip rate variability in the Lower Rhine Embayment, Northwest Europe

    NASA Astrophysics Data System (ADS)

    Gold, Ryan; Kuebler, Simon; Friedrich, Anke

    2016-04-01

    Low strain regions may be characterized by long periods of seismic quiescence, punctuated by periods of clustered earthquake activity. This type of non-periodic recurrence behavior challenges accurate seismic hazard analysis. The Lower Rhine Embayment in the German-Belgium-Netherland border region presents a unique opportunity to characterize the long-term record of faulting to evaluate the periodicity of earthquake occurrence in a low strain region. The Lower Rhine Embayment is covered by a high-resolution record of Quaternary terraces associated with the Rhine and Maas (Meuse) Rivers and their tributaries. These terraces are cut by numerous NW-trending faults and record cumulative displacements that exceed 100 m in numerous locations. In this study, we exploit this rich record of faulted fluvial terraces and find convincing evidence for temporally varying rates of Quaternary fault movement across the Lower Rhine Embayment. First, we document a significant increase in vertical fault slip rates since 700 ka, compared to the average slip rate since the start of the Quaternary using the top and base of the Main Terrace, respectively. Increases in slip rate exceed 500% along many of the faults, including the Swist/Erft, Stockheim, Viersen, Sandgewand, and Kirspenich fault systems. This increase in fault slip rate corresponds to a regional period of increased tectonic uplift of the Rhenish Massif, increased volcanism in Eifel, and incision of the Rhine River. In a second and related analysis, we synthesize terrace offset and age information from the Feldbiss fault system along the western boundary of the Lower Rhine Embayment, which transects a flight of Quaternary terraces associated with the Mass river. This analysis reveals evidence for secular variation in slip rate. In particular, we identify two periods of higher slip rate (800-400 ka and 130-100 ka), where fault slip rate exceeds the longer-term average slip rate of 0.04-0.05 mm/yr by as much as a factor of two. These results show that in the Lower Rhine Embayment low-strain region, the tempo of strain release (and therefore earthquakes) is non-steady. This variable slip behavior should be incorporated into future efforts to characterize seismic hazard across the region.

  16. 17 CFR 240.15c3-1g - Conditions for ultimate holding companies of certain brokers or dealers (Appendix G to 17 CFR 240...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... that: (A) The stock does not have a maturity date; (B) The stock cannot be redeemed at the option of... G; (B) Subordinated debt if the original weighted average maturity of the subordinated debt is at... weighted average maturity of at least five years and that cannot be accelerated, except upon the occurrence...

  17. Forest Fire Occurrence in Southern Counties, 1966-1975

    Treesearch

    M.L. Doolittle

    1977-01-01

    Forest fire occurrence data for individual protection units generally are unavailable outside particular state organization. Number of fires, area protected and fire occurrence rate (fires per 1,000,000 acres) from 1966 to 1975, are presented in tables for the 993 counties under protection in 13 southern states. These data are compared with data for the preceeding...

  18. Convective Cloud Towers and Precipitation Initiation, Frequency and Intensity

    NASA Astrophysics Data System (ADS)

    Vant-hull, B.; Mahani, S. E.; Autones, F.; Rabin, R.; Mecikalski, J. R.; Khanbilvardi, R.

    2012-12-01

    : Geosynchronous satellite retrieval of precipitation is desirable because it would provide continuous observation throughout most of the globe in regions where radar data is not available. In the current work the distribution of precipitation rates is examined as a function of cloud tower area and cloud top temperature. A thunderstorm tracking algorithm developed at Meteo-France is used to track cumulus towers that are matched up with radar data at 5 minute 1 km resolution. It is found that roughly half of the precipitation occurs in the cloud mass that surrounds the towers, and when a tower is first detected the precipitation is already in progress 50% of the time. The average density of precipitation per area is greater as the towers become smaller and colder, yet the averaged shape of the precipitation intensity distribution is remarkably constant in all convective situations with cloud tops warmer than 220 K. This suggests that on average all convective precipitation events look the same, unaffected by the higher frequency of occurrence per area inside the convective towers. Only once the cloud tops are colder than 220 K does the precipitation intensity distribution become weighted towards higher instantaneous intensities. Radar precipitation shown in shades of green to blue, lightning in orange; black diamonds are coldest points in each tower. Ratio of number of pixels of given precipitation inside versus outside the convective towers, for various average cloud top temperatures. A flat plot indicates the distribution of rainfall inside and outside the towers has the same shape.

  19. Spatial and temporal variability in rates of landsliding in seismically active mountain ranges

    NASA Astrophysics Data System (ADS)

    Parker, R.; Petley, D.; Rosser, N.; Densmore, A.; Gunasekera, R.; Brain, M.

    2012-04-01

    Where earthquake and precipitation driven disasters occur in steep, mountainous regions, landslides often account for a large proportion of the associated damage and losses. This research addresses spatial and temporal variability in rates of landslide occurrence in seismically active mountain ranges as a step towards developing better regional scale prediction of losses in such events. In the first part of this paper we attempt to explain reductively the variability in spatial rates of landslide occurrence, using data from five major earthquakes. This is achieved by fitting a regression-based conditional probability model to spatial probabilities of landslide occurrence, using as predictor variables proxies for spatial patterns of seismic ground motion and modelled hillslope stability. A combined model for all earthquakes performs well in hindcasting spatial probabilities of landslide occurrence as a function of readily-attainable spatial variables. We present validation of the model and demonstrate the extent to which it may be applied globally to derive landslide probabilities for future earthquakes. In part two we examine the temporal behaviour of rates of landslide occurrence. This is achieved through numerical modelling to simulate the behaviour of a hypothetical landscape. The model landscape is composed of hillslopes that continually weaken, fail and reset in response to temporally-discrete forcing events that represent earthquakes. Hillslopes with different geometries require different amounts of weakening to fail, such that they fail and reset at different temporal rates. Our results suggest that probabilities of landslide occurrence are not temporally constant, but rather vary with time, irrespective of changes in forcing event magnitudes or environmental conditions. Various parameters influencing the magnitude and temporal patterns of this variability are identified, highlighting areas where future research is needed. This model has important implications for landslide hazard and risk analysis in mountain areas as existing techniques usually assume that susceptibility to failure does not change with time.

  20. THE OCCURRENCE RATE OF SMALL PLANETS AROUND SMALL STARS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dressing, Courtney D.; Charbonneau, David, E-mail: cdressing@cfa.harvard.edu

    We use the optical and near-infrared photometry from the Kepler Input Catalog to provide improved estimates of the stellar characteristics of the smallest stars in the Kepler target list. We find 3897 dwarfs with temperatures below 4000 K, including 64 planet candidate host stars orbited by 95 transiting planet candidates. We refit the transit events in the Kepler light curves for these planet candidates and combine the revised planet/star radius ratios with our improved stellar radii to revise the radii of the planet candidates orbiting the cool target stars. We then compare the number of observed planet candidates to themore » number of stars around which such planets could have been detected in order to estimate the planet occurrence rate around cool stars. We find that the occurrence rate of 0.5-4 R{sub Circled-Plus} planets with orbital periods shorter than 50 days is 0.90{sup +0.04}{sub -0.03} planets per star. The occurrence rate of Earth-size (0.5-1.4 R{sub Circled-Plus }) planets is constant across the temperature range of our sample at 0.51{sub -0.05}{sup +0.06} Earth-size planets per star, but the occurrence of 1.4-4 R{sub Circled-Plus} planets decreases significantly at cooler temperatures. Our sample includes two Earth-size planet candidates in the habitable zone, allowing us to estimate that the mean number of Earth-size planets in the habitable zone is 0.15{sup +0.13}{sub -0.06} planets per cool star. Our 95% confidence lower limit on the occurrence rate of Earth-size planets in the habitable zones of cool stars is 0.04 planets per star. With 95% confidence, the nearest transiting Earth-size planet in the habitable zone of a cool star is within 21 pc. Moreover, the nearest non-transiting planet in the habitable zone is within 5 pc with 95% confidence.« less

  1. The distribution, occurrence and environmental effect of mercury in Chinese coals

    USGS Publications Warehouse

    Zheng, Lingyun; Liu, Gaisheng; Chou, C.-L.

    2007-01-01

    Mercury (Hg) is a toxic, persistent, and globally distributed pollutant due to its characteristic properties such as low melting and boiling points, conversion between chemical forms and participation in biological cycles. During combustion mercury in coal is almost totally emitted to the atmosphere. With a huge amount of coal consumed, coal combustion is one of the main anthropogenic sources of this element in the environment. In this study, Hg data of 1699 coal samples of China has been compiled, and the concentration, distribution, modes of occurrence, and the impact of Hg emissions on the environment are investigated. Most Chinese coals have Hg content in the range of 0.1 to 0.3??ppm, with an average of 0.19??ppm, which is slightly higher than the average Hg content of world coals and is close to that of the U.S. coals. The Hg content in coals varies in different coal basins, geological ages and coal ranks. The most likely mode of occurrences of Hg in high-sulfur and high Hg content coals is as solid solution in pyrite. But in low-sulfur coals, modes of occurrence of Hg are variable, and the organic-bound and sulfide-bound Hg may dominate. Silicate-bound Hg may be the main form in some coals because of magmatic intrusion. Mercury emissions during coal combustion have resulted in serious environmental contamination in China, particularly in the northeastern and southwestern China, where a high Hg content in the atmosphere occurs. ?? 2007 Elsevier B.V. All rights reserved.

  2. No support for Heincke's law in hagfish (Myxinidae): lack of an association between body size and the depth of species occurrence.

    PubMed

    Schumacher, E L; Owens, B D; Uyeno, T A; Clark, A J; Reece, J S

    2017-08-01

    This study tests for interspecific evidence of Heincke's law among hagfishes and advances the field of research on body size and depth of occurrence in fishes by including a phylogenetic correction and by examining depth in four ways: maximum depth, minimum depth, mean depth of recorded specimens and the average of maximum and minimum depths of occurrence. Results yield no evidence for Heincke's law in hagfishes, no phylogenetic signal for the depth at which species occur, but moderate to weak phylogenetic signal for body size, suggesting that phylogeny may play a role in determining body size in this group. © 2017 The Fisheries Society of the British Isles.

  3. Species biogeography predicts drought responses in a seasonally dry tropical forest

    NASA Astrophysics Data System (ADS)

    Schwartz, N.; Powers, J. S.; Vargas, G.; Xu, X.; Smith, C. M.; Brodribb, T.; Werden, L. K.; Becknell, J.; Medvigy, D.

    2017-12-01

    The timing, distribution, and amount of rainfall in the seasonal tropics have shifted in recent years, with consequences for seasonally dry tropical forests (SDTF). SDTF are sensitive to changing rainfall regimes and drought conditions, but sensitivity to drought varies substantially across species. One potential explanation of species differences is that species that experience dry conditions more frequently throughout their range will be better able to cope with drought than species from wetter climates, because species from drier climates will be better adapted to drought. An El-Niño induced drought in 2015 presented an opportunity to assess species-level differences in mortality in SDTF, and to ask whether the ranges of rainfall conditions species experience and the average rainfall regimes in species' ranges predict differences in mortality rates in Costa Rican SDTF. We used field plot data from northwest Costa Rica to determine species' level mortality rates. Mortality rates ranged substantially across species, with some species having no dead individuals to as high as 50% mortality. To quantify rainfall conditions across species' ranges, we used species occurrence data from the Global Biodiversity Information Facility, and rainfall data from the Chelsa climate dataset. We found that while the average and range of mean annual rainfall across species ranges did not predict drought-induced mortality in the field plots, across-range averages of the seasonality index, a measure of rainfall seasonality, was strongly correlated with species-level drought mortality (r = -0.62, p < 0.05), with species from more strongly seasonal climates experiencing less severe drought mortality. Furthermore, we found that the seasonality index was a stronger predictor of mortality than any individual functional trait we considered. This result shows that species' biogeography may be an important factor for how species will respond to future drought, and may be a more integrative predictor than individual functional traits.

  4. Characteristics of magnetic clouds/magnetic-cloud-like structures during the years 1995-2003

    NASA Astrophysics Data System (ADS)

    Wu, C. C.; Lepping, R.

    Using nine years of solar wind plasma and magnetic field data we investigated the characteristics of both magnetic clouds MCs and magnetic cloud like structures MCLs during 1995-2003 A MCL structure is an event which was identified by an automatic scheme Lepping et al 2005 with the same criteria as for a MC but is not identifiable as a flux rope by using the MC Burlaga 1981 fitting model developed by Lepping et al 1990 The average occurrence rate is sim 9 5 for MCs and sim 13 6 for MCLs per year for the overall period of interest and there were 82 MCs and 122 MCLs identified during this period The characteristics of MCs and MCL structures are as follows 1 The averaged duration Dt of MCs is 21 1 hour which is 40 longer than MCLs Dt 15 hrs 2 The averaged Bz min minimum Bz found in MC MCL is -10 2 nT for MCs and -6 nT for MCLs 3 The averaged Dst min minimum Dst caused by MC MCL is -82 nT for MCs and -37 nT for MCLs 4 The average of the solar wind velocity is 453 km s for MCs and 413 km s for MCLs 5 The average of the thermal speed is 24 6 km s for MCs and 27 7 km s for MCLs 6 The average of the magnetic field intensity is 12 7 nT for MCs and 9 8 nT for MCLs and 7 The average of the solar wind density is 9 4 cm -3 for MCs and 6 3 cm -3 for MCLs The longer duration more intense magnetic field and higher solar wind speed and denisty of MCs compared to those of the MCLs might be the major reason for generally causing geomagnetic storms with higher

  5. Peculiar alexithymic traits in burning mouth syndrome: case-control study.

    PubMed

    Marino, Roberto; Picci, Rocco Luigi; Ferro, Giovanni; Carezana, Claudio; Gandolfo, Sergio; Pentenero, Monica

    2015-11-01

    The present case-control study aims to assess the occurrence of alexithymic traits in burning mouth syndrome (BMS) subjects and to correlate alexithymic traits to anxious and depressive traits in BMS subjects. Prospectively enrolled BMS and control subjects were administered the 20-item Toronto Alexithymia Scale (TAS-20). Anxiety and depressive traits were assessed using the Hamilton Anxiety Rating Scale and the Montgomery and Asberg Depression Rating Scale. Occurrence of alexithymic traits was compared between BMS and control subjects. Correlation tests were used to measure the importance of alexithymic traits related to demographic characteristics, pain intensity (VAS score), and to the other psychometric scores. Fifty-eight BMS subjects (46 females and 12 males) had a mean TAS-20 score significantly higher when compared to controls (p < 0.001; r = 0.72), corresponding to an occurrence rate of alexithymic traits of 79.3 versus 6.9%. Alexithymic traits in BMS subjects were just related to depressive traits (p = 0.02; ρ = 0.31). The high occurrence of alexithymia in BMS is an adjunctive issue in favor of its multifactorial pathogenesis, with a not negligible role for somatization. Clinicians should be aware of the high occurrence of alexithymic traits among BMS subjects as such traits may affect the doctor-patient relationship.

  6. Using an autologistic regression model to identify spatial risk factors and spatial risk patterns of hand, foot and mouth disease (HFMD) in Mainland China

    PubMed Central

    2014-01-01

    Background There have been large-scale outbreaks of hand, foot and mouth disease (HFMD) in Mainland China over the last decade. These events varied greatly across the country. It is necessary to identify the spatial risk factors and spatial distribution patterns of HFMD for public health control and prevention. Climate risk factors associated with HFMD occurrence have been recognized. However, few studies discussed the socio-economic determinants of HFMD risk at a space scale. Methods HFMD records in Mainland China in May 2008 were collected. Both climate and socio-economic factors were selected as potential risk exposures of HFMD. Odds ratio (OR) was used to identify the spatial risk factors. A spatial autologistic regression model was employed to get OR values of each exposures and model the spatial distribution patterns of HFMD risk. Results Results showed that both climate and socio-economic variables were spatial risk factors for HFMD transmission in Mainland China. The statistically significant risk factors are monthly average precipitation (OR = 1.4354), monthly average temperature (OR = 1.379), monthly average wind speed (OR = 1.186), the number of industrial enterprises above designated size (OR = 17.699), the population density (OR = 1.953), and the proportion of student population (OR = 1.286). The spatial autologistic regression model has a good goodness of fit (ROC = 0.817) and prediction accuracy (Correct ratio = 78.45%) of HFMD occurrence. The autologistic regression model also reduces the contribution of the residual term in the ordinary logistic regression model significantly, from 17.25 to 1.25 for the odds ratio. Based on the prediction results of the spatial model, we obtained a map of the probability of HFMD occurrence that shows the spatial distribution pattern and local epidemic risk over Mainland China. Conclusions The autologistic regression model was used to identify spatial risk factors and model spatial risk patterns of HFMD. HFMD occurrences were found to be spatially heterogeneous over the Mainland China, which is related to both the climate and socio-economic variables. The combination of socio-economic and climate exposures can explain the HFMD occurrences more comprehensively and objectively than those with only climate exposures. The modeled probability of HFMD occurrence at the county level reveals not only the spatial trends, but also the local details of epidemic risk, even in the regions where there were no HFMD case records. PMID:24731248

  7. Study of ionospheric irregularities from Kolhapur (16.4°N, 74.2°E)

    NASA Astrophysics Data System (ADS)

    Sharma, A. K.; Chavan, G. A.; Gaikwad, H. P.; Gurav, O. B.; Nade, D. P.; Nikte, S. S.; Ghodpage, R. N.; Patil, P. T.

    2018-04-01

    The paper reports night time observations of ionospheric irregularities made through amplitude scintillation of 251 MHz signal at Kolhapur (16.4°N, 74.2°E), an equatorial Appleton anomaly region using spaced antenna system. Monthly and night time percentage of occurrence of scintillations, during increasing solar cycle from January 2011 to August 2015, is discussed. The parameters such as-maximum cross-correlation function (CI), Fade Rate are also studied. The percentage occurrence is observed to be higher in post sunset period and during equinoctial months than in winter and summer months. Scintillation occurrence is observed to be suppressed during increasing solar activity. CI shows seasonal changes. Percentage of occurrence of CI ≥ 0.5 decreases with increase in solar activity and fade rate also shows solar activity dependence.

  8. Separate Vertical Wirings for the Extra-articular Fractures of the Distal Pole of the Patella.

    PubMed

    Kim, Young Mo; Yang, Jun Young; Kim, Kyung Cheon; Kang, Chan; Joo, Yong Bum; Lee, Woo Yong; Hwang, Jung Mo

    2011-12-01

    To evaluate the usefulness of separate vertical wirings for extra-articular fracture of distal pole of patella. We have analyzed the clinical results of 18 cases that underwent separate vertical wirings for extra-articular fracture of distal pole of the patella from March 2005 to March 2010, by using the range of motion and Bostman score. Occurrence of complication was also evaluated. Additionally, by taking simple radiographs, the correlation between the postoperative degree of anterior transposition of bone fragment and the time of bone fusion, preoperative length of bone fragment, and occurrence of comminuted fracture were investigated. It took an average of 13.8 weeks for radiological bone union after separate vertical wiring fixation. Flexion contracture was an average of 0.8 degrees and further flexion was an average of 127.6°, and Bostman score was an average of 27.5 points (excellent in 12 cases, and good in 6 cases). On the first postoperative year, average flexion contracture was 0.6 degrees and further flexion was an average of 136.3°, which exhibited increased joint motion and recovery to normal range of motion, and Bostman score was an average of 28.7 points (excellent in 16 cases, and good in 2 cases). There was no statistically significant difference between the preoperative bone fragment length and presence of comminution, and degree of anterior transposition of bone fragment after fracture union on simple radiograph (p=0.175, p=0.146). We were able to obtain satisfactory clinical results, while preserving the bone fragment by separate vertical wiring fixation for extra-articular fracture of distal pole of patella. Moreover, the method is easy to perform, which is also considered as a useful surgical method for extra-articular fracture of distal pole of patella.

  9. Graduation of fertility schedules: an analysis of fertility patterns in London in the 1980s and an application to fertility forecasts.

    PubMed

    Congdon, P

    1990-08-01

    London's average total fertility rate (TFR) stood at 1.75. Using a cluster analysis to compare the 1985-1987 fertility patterns of different boroughs of London, demographers learned that 5 natural groupings occurred. 4 boroughs in a central London cluster have the distinction of having a low TFR (1.38) and late fertility (average age of 29.58 years). The researchers attributed these occurrences to the high levels of employment and career attachment and low rates of marriage among women in this cluster. 2 inner city boroughs constituted the smallest cluster and had the largest TFR (2.37), mainly due to high numbers of births to the ethnic minorities. The largest cluster consisted of 12 boroughs located mainly along the periphery with 2 centrally located boroughs (TFR, 1.79). Some of the upper class outer boroughs characterized another cluster with a TFR of 1.61. Another cluster made up of inner and outer boroughs in east and southeast London had a ample proportion of manual worker (TFR, 2.04). Social class most likely accounted for the contrast in TFRs between the 2 aformentioned clusters. Demographers observed that cyclical fluctuation of fertility occurred as opposed to secular trends. Due to these fluctuations, demographers used autoregressive moving average forecast models to time series of the fertility variables in London since 1952. They also applied structural time series models which included regression variables and the influence of cyclical and/or trend behavior. The results showed that large cohorts and the increase in female economic activity caused a delay in the modal age of births and a reduction in the number of births.

  10. Permutation entropy analysis of heart rate variability for the assessment of cardiovascular autonomic neuropathy in type 1 diabetes mellitus.

    PubMed

    Carricarte Naranjo, Claudia; Sanchez-Rodriguez, Lazaro M; Brown Martínez, Marta; Estévez Báez, Mario; Machado García, Andrés

    2017-07-01

    Heart rate variability (HRV) analysis is a relevant tool for the diagnosis of cardiovascular autonomic neuropathy (CAN). To our knowledge, no previous investigation on CAN has assessed the complexity of HRV from an ordinal perspective. Therefore, the aim of this work is to explore the potential of permutation entropy (PE) analysis of HRV complexity for the assessment of CAN. For this purpose, we performed a short-term PE analysis of HRV in healthy subjects and type 1 diabetes mellitus patients, including patients with CAN. Standard HRV indicators were also calculated in the control group. A discriminant analysis was used to select the variables combination with best discriminative power between control and CAN patients groups, as well as for classifying cases. We found that for some specific temporal scales, PE indicators were significantly lower in CAN patients than those calculated for controls. In such cases, there were ordinal patterns with high probabilities of occurrence, while others were hardly found. We posit this behavior occurs due to a decrease of HRV complexity in the diseased system. Discriminant functions based on PE measures or probabilities of occurrence of ordinal patterns provided an average of 75% and 96% classification accuracy. Correlations of PE and HRV measures showed to depend only on temporal scale, regardless of pattern length. PE analysis at some specific temporal scales, seem to provide additional information to that obtained with traditional HRV methods. We concluded that PE analysis of HRV is a promising method for the assessment of CAN. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Dynamical and statistical phenomena of circulation and heat transfer in periodically forced rotating turbulent Rayleigh-Bénard convection

    NASA Astrophysics Data System (ADS)

    Sterl, Sebastian; Li, Hui-Min; Zhong, Jin-Qiang

    2016-12-01

    In this paper, we present results from an experimental study into turbulent Rayleigh-Bénard convection forced externally by periodically modulated unidirectional rotation rates. We find that the azimuthal rotation velocity θ ˙(t ) and thermal amplitude δ (t ) of the large-scale circulation (LSC) are modulated by the forcing, exhibiting a variety of dynamics including increasing phase delays and a resonant peak in the amplitude of θ ˙(t ) . We also focus on the influence of modulated rotation rates on the frequency of occurrence η of stochastic cessation or reorientation events, and on the interplay between such events and the periodically modulated response of θ ˙(t ) . Here we identify a mechanism by which η can be amplified by the modulated response, and these normally stochastic events can occur with high regularity. We provide a modeling framework that explains the observed amplitude and phase responses, and we extend this approach to make predictions for the occurrence of cessation events and the probability distributions of θ ˙(t ) and δ (t ) during different phases of a modulation cycle, based on an adiabatic approach that treats each phase separately. Last, we show that such periodic forcing has consequences beyond influencing LSC dynamics, by investigating how it can modify the heat transport even under conditions where the Ekman pumping effect is predominant and strong enhancement of heat transport occurs. We identify phase and amplitude responses of the heat transport, and we show how increased modulations influence the average Nusselt number.

  12. Phylogenetic fields through time: temporal dynamics of geographical co-occurrence and phylogenetic structure within species ranges

    PubMed Central

    Carotenuto, Francesco; Diniz-Filho, José Alexandre F.

    2016-01-01

    Species co-occur with different sets of other species across their geographical distribution, which can be either closely or distantly related. Such co-occurrence patterns and their phylogenetic structure within individual species ranges represent what we call the species phylogenetic fields (PFs). These PFs allow investigation of the role of historical processes—speciation, extinction and dispersal—in shaping species co-occurrence patterns, in both extinct and extant species. Here, we investigate PFs of large mammalian species during the last 3 Myr, and how these correlate with trends in diversification rates. Using the fossil record, we evaluate species' distributional and co-occurrence patterns along with their phylogenetic structure. We apply a novel Bayesian framework on fossil occurrences to estimate diversification rates through time. Our findings highlight the effect of evolutionary processes and past climatic changes on species' distributions and co-occurrences. From the Late Pliocene to the Recent, mammal species seem to have responded in an individualistic manner to climate changes and diversification dynamics, co-occurring with different sets of species from different lineages across their geographical ranges. These findings stress the difficulty of forecasting potential effects of future climate changes on biodiversity. PMID:26977061

  13. Phylogenetic fields through time: temporal dynamics of geographical co-occurrence and phylogenetic structure within species ranges.

    PubMed

    Villalobos, Fabricio; Carotenuto, Francesco; Raia, Pasquale; Diniz-Filho, José Alexandre F

    2016-04-05

    Species co-occur with different sets of other species across their geographical distribution, which can be either closely or distantly related. Such co-occurrence patterns and their phylogenetic structure within individual species ranges represent what we call the species phylogenetic fields (PFs). These PFs allow investigation of the role of historical processes--speciation, extinction and dispersal--in shaping species co-occurrence patterns, in both extinct and extant species. Here, we investigate PFs of large mammalian species during the last 3 Myr, and how these correlate with trends in diversification rates. Using the fossil record, we evaluate species' distributional and co-occurrence patterns along with their phylogenetic structure. We apply a novel Bayesian framework on fossil occurrences to estimate diversification rates through time. Our findings highlight the effect of evolutionary processes and past climatic changes on species' distributions and co-occurrences. From the Late Pliocene to the Recent, mammal species seem to have responded in an individualistic manner to climate changes and diversification dynamics, co-occurring with different sets of species from different lineages across their geographical ranges. These findings stress the difficulty of forecasting potential effects of future climate changes on biodiversity. © 2016 The Author(s).

  14. Road Traffic Injury Trends in the City of Valledupar, Colombia. A Time Series Study from 2008 to 2012

    PubMed Central

    Rodríguez, Jorge Martín; Peñaloza, Rolando Enrique; Moreno Montoya, José

    2015-01-01

    Objective To analyze the behavior temporal of road-traffic injuries (RTI) in Valledupar, Colombia from January 2008 to December 2012. Methodology An observational study was conducted based on records from the Colombian National Legal Medicine and Forensic Sciences Institute regional office in Valledupar. Different variables were analyzed, such as the injured person’s sex, age, education level, and type of road user; the timeframe, place and circumstances of crashes and the vehicles associated with the occurrence. Furthermore, a time series analysis was conducted using an auto-regressive integrated moving average. Results There were 105 events per month on an average, 64.9% of RTI involved men; 82.3% of the persons injured were from 18 to 59 years of age; the average age was 35.4 years of age; the road users most involved in RTI were motorcyclists (69%), followed by pedestrians (12%). 70% had up to upper-secondary education. Sunday was the day with the most RTI occurrences; 93% of the RTI occurred in the urban area. The time series showed a seasonal pattern and a significant trend effect. The modeling process verified the existence of both memory and extrinsic variables related. Conclusions An RTI occurrence pattern was identified, which showed an upward trend during the period analyzed. Motorcyclists were the main road users involved in RTI, which suggests the need to design and implement specific measures for that type of road user, from regulations for graduated licensing for young drivers to monitoring road user behavior for the promotion of road safety. PMID:26657887

  15. Road Traffic Injury Trends in the City of Valledupar, Colombia. A Time Series Study from 2008 to 2012.

    PubMed

    Rodríguez, Jorge Martín; Peñaloza, Rolando Enrique; Moreno Montoya, José

    2015-01-01

    To analyze the behavior temporal of road-traffic injuries (RTI) in Valledupar, Colombia from January 2008 to December 2012. An observational study was conducted based on records from the Colombian National Legal Medicine and Forensic Sciences Institute regional office in Valledupar. Different variables were analyzed, such as the injured person's sex, age, education level, and type of road user; the timeframe, place and circumstances of crashes and the vehicles associated with the occurrence. Furthermore, a time series analysis was conducted using an auto-regressive integrated moving average. There were 105 events per month on an average, 64.9% of RTI involved men; 82.3% of the persons injured were from 18 to 59 years of age; the average age was 35.4 years of age; the road users most involved in RTI were motorcyclists (69%), followed by pedestrians (12%). 70% had up to upper-secondary education. Sunday was the day with the most RTI occurrences; 93% of the RTI occurred in the urban area. The time series showed a seasonal pattern and a significant trend effect. The modeling process verified the existence of both memory and extrinsic variables related. An RTI occurrence pattern was identified, which showed an upward trend during the period analyzed. Motorcyclists were the main road users involved in RTI, which suggests the need to design and implement specific measures for that type of road user, from regulations for graduated licensing for young drivers to monitoring road user behavior for the promotion of road safety.

  16. Wiring Damage Analyses for STS OV-103

    NASA Technical Reports Server (NTRS)

    Thomas, Walter, III

    2006-01-01

    This study investigated the Shuttle Program s belief that Space Transportation System (STS) wiring damage occurrences are random, that is, a constant occurrence rate. Using Problem Reporting and Corrective Action (PRACA)-derived data for STS Space Shuttle OV-103, wiring damage was observed to increase over the vehicle s life. Causal factors could include wiring physical deterioration, maintenance and inspection induced damage, and inspection process changes resulting in more damage events being reported. Induced damage effects cannot be resolved with existent data. Growth analysis (using Crow-AMSAA, or CA) resolved maintenance/inspection effects (e.g., heightened awareness) on all wire damages and indicated an overall increase since Challenger Return-to-Flight (RTF). An increasing failure or occurrence rate per flight cycle was seen for each wire damage mode; these (individual) rates were not affected by inspection process effects, within statistical error.

  17. Linking Satellite Derived Land Surface Temperature with Cholera: A Case Study for South Sudan

    NASA Astrophysics Data System (ADS)

    Aldaach, H. S. V.; Jutla, A.; Akanda, A. S.; Colwell, R. R.

    2014-12-01

    A sudden onset of cholera in South Sudan, in April 2014 in Northern Bari in Juba town resulted in more than 400 cholera cases after four weeks of initial outbreak with a case of fatality rate of CFR 5.4%. The total number of reported cholera cases for the period of April to July, 2014 were 5,141 including 114 deaths. With the limited efficacy of cholera vaccines, it is necessary to develop mechanisms to predict cholera occurrence and thereafter devise intervention strategies for mitigating impacts of the disease. Hydroclimatic processes, primarily precipitation and air temperature are related to epidemic and episodic outbreak of cholera. However, due to coarse resolution of both datasets, it is not possible to precisely locate the geographical location of disease. Here, using Land Surface Temperature (LST) from MODIS sensors, we have developed an algorithm to identify regions susceptible for cholera. Conditions for occurrence of cholera were detectable at least one month in advance in South Sudan and were statistically sensitive to hydroclimatic anomalies of land surface and air temperature, and precipitation. Our results indicate significant spatial and temporal averaging required to infer usable information from LST over South Sudan. Preliminary results that geographically location of cholera outbreak was identifiable within 1km resolution of the LST data.

  18. Simulations of wind erosion along the Qinghai-Tibet Railway in north-central Tibet

    NASA Astrophysics Data System (ADS)

    Jiang, Yingsha; Gao, Yanhong; Dong, Zhibao; Liu, Benli; Zhao, Lin

    2018-06-01

    Wind erosion along the Qinghai-Tibet Railway causes sand hazard and poses threats to the safety of trains and passengers. A coupled land-surface erosion model (Noah-MPWE) was developed to simulate the wind erosion along the railway. Comparison with the data from the 137Cs isotope analysis shows that this coupled model could simulate the mean erosion amount reasonably. The coupled model was then applied to eight sites along the railway to investigate the wind-erosion distribution and variations from 1979 to 2012. Factors affecting wind erosion spatially and temporally were assessed as well. Majority wind erosion occurs in the non-monsoon season from December to April of the next year except for the site located in desert. The region between Wudaoliang and Tanggula has higher wind erosion occurrences and soil lose amount because of higher frequency of strong wind and relatively lower soil moisture than other sites. Inter-annually, all sites present a significant decreasing trend of annual soil loss with an average rate of -0.18 kg m-2 a-1 in 1979-2012. Decreased frequency of strong wind, increased precipitation and soil moisture contribute to the reduction of wind erosion in 1979-2012. Snow cover duration and vegetation coverage also have great impact on the occurrence of wind erosion.

  19. Individual and Combined Occurrence of Mycotoxins in Feed Ingredients and Complete Feeds in China.

    PubMed

    Ma, Rui; Zhang, Lei; Liu, Meng; Su, Yong-Teng; Xie, Wen-Mei; Zhang, Ni-Ya; Dai, Jie-Fan; Wang, Yun; Rajput, Shahid Ali; Qi, De-Sheng; Karrow, Niel Alexander; Sun, Lv-Hui

    2018-03-07

    The objective of this study was to investigate the individual and combined contamination of aflatoxin B₁ (AFB₁), zearalenone (ZEN) and deoxynivalenol (DON) in feedstuffs from different Provinces of China between 2016 and 2017. A total of 1569 samples, including 742 feed ingredients and 827 complete pig feed samples, were collected from various regions of China for mycotoxins analysis. The results showed that individual occurrence rates of AFB₁, ZEN, and DON were more than 83.3%, 88%, and 74.5%, respectively, in all the tested samples. DON was the most prevalent contaminant, followed by ZEN and AFB₁, with the average concentrations ranging from 450.0-4381.5 μg/kg, 2.3-729.2 μg/kg, and 1.3-10.0 μg/kg, respectively. Notable, 38.2%, 10.8%, and 0.6% of complete pig feeds were contaminated with DON, ZEN, and AFB₁ over China's regulatory limits, respectively. Moreover, over 75.0% analyzed samples were co-contaminated with two or three mycotoxins. In conclusion, the current study revealed that the feedstuffs in China were severely contaminated with DON, followed by ZEN and AFB₁ during the past two years. These findings highlight the importance of monitoring mycotoxins in livestock feed and implementing feed management and bioremediation strategies to reduce mycotoxin exposure.

  20. Bioenergetics assessment of fish and crayfish consumption by river otter (Lontra canadensis): integrating prey availability, diet, and field metabolic rate

    USGS Publications Warehouse

    Dekar, Matthew P.; Magoulick, Daniel D.; Beringer, J.

    2010-01-01

    River otters (Lontra canadensis) are important predators in aquatic ecosystems, but few studies quantify their prey consumption. We trapped crayfish monthly as an index of availability and collected otter scat for diet analysis in the Ozark Mountains of northwestern Arkansas, USA. We measured otter daily energy expenditure (DEE) with the doubly labeled water method to develop a bioenergetics model for estimating monthly prey consumption. Meek's crayfish (Orconectes meeki) catch-per-unit-effort was positively related to stream temperature, indicating that crayfish were more available during warmer months. The percentage frequency of occurrence for crayfish in scat samples peaked at 85.0% in summer and was lowest (42.3%) in winter. In contrast, the percentage occurrence of fish was 13.3% in summer and 57.7% in winter. Estimates of DEE averaged 4738 kJ·day-1 for an otter with a body mass of 7842 g. Total biomass consumption ranged from 35 079 to 52 653 g·month-1 (wet mass), corresponding to a high proportion of fish and crayfish in the diet, respectively. Otter consumption represents a large fraction of prey production, indicating potentially strong effects of otters on trophic dynamics in stream ecosystems.

  1. Does probability of occurrence relate to population dynamics?

    USGS Publications Warehouse

    Thuiller, Wilfried; Münkemüller, Tamara; Schiffers, Katja H.; Georges, Damien; Dullinger, Stefan; Eckhart, Vincent M.; Edwards, Thomas C.; Gravel, Dominique; Kunstler, Georges; Merow, Cory; Moore, Kara; Piedallu, Christian; Vissault, Steve; Zimmermann, Niklaus E.; Zurell, Damaris; Schurr, Frank M.

    2014-01-01

    Hutchinson defined species' realized niche as the set of environmental conditions in which populations can persist in the presence of competitors. In terms of demography, the realized niche corresponds to the environments where the intrinsic growth rate (r) of populations is positive. Observed species occurrences should reflect the realized niche when additional processes like dispersal and local extinction lags do not have overwhelming effects. Despite the foundational nature of these ideas, quantitative assessments of the relationship between range-wide demographic performance and occurrence probability have not been made. This assessment is needed both to improve our conceptual understanding of species' niches and ranges and to develop reliable mechanistic models of species geographic distributions that incorporate demography and species interactions.The objective of this study is to analyse how demographic parameters (intrinsic growth rate r and carrying capacity K ) and population density (N ) relate to occurrence probability (Pocc ). We hypothesized that these relationships vary with species' competitive ability. Demographic parameters, density, and occurrence probability were estimated for 108 tree species from four temperate forest inventory surveys (Québec, western USA, France and Switzerland). We used published information of shade tolerance as indicators of light competition strategy, assuming that high tolerance denotes high competitive capacity in stable forest environments.Interestingly, relationships between demographic parameters and occurrence probability did not vary substantially across degrees of shade tolerance and regions. Although they were influenced by the uncertainty in the estimation of the demographic parameters, we found that r was generally negatively correlated with Pocc, while N, and for most regions K, was generally positively correlated with Pocc. Thus, in temperate forest trees the regions of highest occurrence probability are those with high densities but slow intrinsic population growth rates. The uncertain relationships between demography and occurrence probability suggests caution when linking species distribution and demographic models.

  2. Risk of Alcohol-Impaired Driving Recidivism Among First Offenders and Multiple Offenders

    PubMed Central

    Zador, Paul L.; Ahlin, Eileen M.; Howard, Jan M.; Frissell, Kevin C.; Duncan, G. Doug

    2010-01-01

    Objectives. We sought to determine the statewide impact of having prior alcohol-impaired driving violations of any type on the rate of first occurrence or recidivism among drivers with 0, 1, 2, or 3 or more prior violations in Maryland. Methods. We analyzed more than 100 million driver records from 1973 to 2004 and classified all Maryland drivers into 4 groups: those with 0, 1, 2, or 3 or more prior violations. The violation rates for approximately 21 million drivers in these 4 groups were compared for the study period 1999 to 2004. Results. On average, there were 3.4, 24.3, 35.9, and 50.8 violations per 1000 drivers a year among those with 0, 1, 2, or 3 or more priors, respectively. The relative risks for men compared with women among these groups of drivers were 3.8, 1.2, 1.0, and 1.0, respectively. Conclusions. The recidivism rate among first offenders more closely resembles that of second offenders than of nonoffenders. Men and women are at equal risk of recidivating once they have had a first violation documented. Any alcohol-impaired driving violation, not just convictions, is a marker for future recidivism. PMID:19846687

  3. Improving SysSim's Planetary Occurrence Rate Estimates

    NASA Astrophysics Data System (ADS)

    Ashby, Keir; Ragozzine, Darin; Hsu, Danley; Ford, Eric B.

    2017-10-01

    Kepler's catalog of thousands of transiting planet candidates enables statistical characterization of the underlying planet occurrence rates as a function of period and radius. Due to geometric factors and general noise in measurements, we know that many planets--especially those with a small-radius and/or long-period--were not observed by Kepler.To account for Kepler's detection criteria, Hsu et al. 2017 expanded on work in Lissuaer et al. 2011 to develop the Planetary System Simulator or "SysSim". SysSim uses a forward model to generate simulated catalogs of exoplanet systems, determine which of those simulated planets would have been seen by Kepler in the presence of uncertainties, and then compares those “observed planets” to those actually seen by Kepler. It then uses Approximate Bayesian Computation to infer the posterior probability distributions of the input parameters used to generate the forward model. In Hsu et al. 2017, we focused on matching the observed frequency of planets by solving for the underlying occurrence rate for each bin in a 2-dimensional grid of radius and period. After summarizing the results of Hsu et al. 2017, we show new results that investigate the effect on occurrence rates from including more accurate completeness products (from the Kepler DR25 analysis) into SysSim.

  4. 10Be erosion rates controlled by normal fault activity through incision and landslide occurrence

    NASA Astrophysics Data System (ADS)

    Roda-Boluda, Duna; D'Arcy, Mitch; Whittaker, Alex; Gheorghiu, Delia; Rodes, Angel

    2017-04-01

    Quantifying erosion rates, and how they compare to rock uplift rates, is fundamental for understanding the evolution of relief and the associated sediment fluxes. The competing effects of rock uplift and erosion are clearly captured by river incision and landsliding, but linking these four important landscape processes remains a major challenge. We address these questions using field data from southern Italy, and quantify the geomorphic response to tectonic forcing. We present 15 new 10Be catchment-averaged erosion rates, collected from catchments along five active normal faults with excellent slip rate constraints. We find that erosion rates are strongly controlled by fault slip rates and that this relationship is mediated by the degree of catchment incision and landslide activity. We find that 10Be samples from low-relief, unincised areas above knickpoints yield consistent erosion rates of ˜ 0.12 mm/yr, while samples collected below knickpoints have erosion rates of ˜ 0.2 - 1.0 mm/yr. This comparison allows us to quantify the impact that transient incisional response has on erosion rates. We demonstrate that in this area incision is associated with frequent, shallow landsliding, and we show that the volumes of landslides stored in the catchments are highly correlated with 10Be-derived sediment flux estimates, suggesting that landslides are likely to be a major contributor to erosional fluxes. Despite widespread landsliding, CRN samples from the studied catchments do provide reliable estimates of catchment-averaged erosion rates, as these are consistent with fault throw patterns and rates. We suggest that this is because landslides are frequent, small and shallow, and are stored on the hillslopes for up to ˜ 103 yrs, representing the integrated record of landsliding over several seismic cycles; and test this hypothesis using a numerical model of landsliding and CRN dynamics. Our results show that adequate CRN mixing can occur through runoff as landslides are stored on the hillslopes, as long as landslide recurrence intervals are short, which is supported by the erosion rate magnitudes and previous landslide studies in the area. This study contributes to our understanding of erosion and sediment supply in tectonically-active areas, and offers novel insights into the use of CRN to infer erosion rates in areas of intense landslide activity.

  5. The GIS Database of floods in Northern Portugal, between 1865 and 2011

    NASA Astrophysics Data System (ADS)

    Santos, Monica; Bateira, Carlos; Hermenegildo, Carlos; Matos, Fátima

    2014-05-01

    Natural hazards, such as floods, cause considerable damage to the human life, material and functional damages every year. Thus, we created a GIS (Geographic Information System) database of floods recorded in the Northern Region of Portugal between 1865 and 2011. The research focused on the study of occurrences in newspapers of national and regional reference that caused some kind of damage. The results show that of the total of 1867 records in 147 years in analysis, 27% of occurrences have resulted in direct consequences on the population, i.e., killed, injured, missing, displaced or evacuated. These occurrences, 65% correspond to river flooding, 16% to flash floods and 18% to urban flooding. In period of analyses, there were 201 killed, 58 injured, 34 missing, 1813 evacuated, and 15924 displaced. By the natural breaks method of classification of data, we can divide the data series into 3 classes: until 1930, 1931-1971 and 1972-2011. Until 1930, the average number of occurrences per year is 5. Thereafter, until 1971, there was a significant increase for 24 occurrences per year. In the period 1972-2011, the average number of occurrences is 13.5 per year. The entire series, we highlight the years 1909, 1939, 1955 and 2001 with over 80 occurrences / year. We applied the Mann-Kendall (Kendall, 1976; Salmi, Määttä, Anttila, Ruoho-Airola, & Amnell, 2002) non-parametric test to detect long term trends in the occurrences. In order to estimate the magnitude of the trends, we used the algorithm that corresponds to an extension of the original test put forward by Theil (1950) and Sen (1968)(Sen, 1968). The results suggest a small upward trend, statistically significant, between 1865 and 2011, an increase of 0,066 occurrences per year. However, this general trend presents significant oscillations, when analysed over shorter periods of time. In terms of geographical distribution, the urban centres and the areas along major rivers concentrate most of the occurrences. The biggest number of occurrences occurs in Oporto metropolitan area, followed by the Braga, Ponte de Lima and Viana do Castelo municipalities. The Douro river basin is the watershed with more occurrences. This database is primarily intended to support the development of studies on the risk associated with these occurrences, analysing their spatial and temporal distribution, the susceptibility of the territories and the vulnerability of the elements exposed. References Kendall, S. . (1976). Time Series (Oxford Univ. Press ed.). New York. Salmi, T., Määttä, A., Anttila, P., Ruoho-Airola, T. , & Amnell, T. . (2002). Detecting Trends of Annual Values of Atmospheric Pollutants by the Mann-Kendall Test and Sen's Slope Estimates - The Excel Template Application MAKESENS (Vol. Publications on Air Quality ). Helsinki: Finnish Meteorological Institute. Sen, P.K. (1968). Estimates of the regression coefficient based on Kendall's tau. J. Am. Stat. Assoc., 63, 1379-1389. Theil, H. (1950). A rank-invariant method of linear and polynomial regression analysis. I, II, III. Nederl. Akad. Wetensch. Proc., 53, 386-392, 521-525, 1397-1412.

  6. Viral Hepatitis in the United States Navy and Marine Corps 1

    PubMed Central

    Alexander, Charles E.

    1976-01-01

    Two analyses of the Navy and Marine Corps experience with viral hepatitis are reported. The first is longitudinal in nature and shows that over the past 100 years the syndrome has been common and at a relatively steady rate of 100-400 cases/100,000 average strength/year. The second is an examination of cases in calendar year 1974 for demographic, geographic, and occupational patterns. There is a strong inverse relationship between disease occurrence and age. Each type of viral hepatitis shows a distinct geographic distribution. Navy personnel in health-related occupations had a greater risk of acquiring viral hepatitis than did other persons on active duty. Differences among other occupational groups were found, but valid interpretations could not be made because of the small numbers of cases in each category. PMID:960729

  7. Sporadic emission of ultra high energy gamma rays from Crab pulsar

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhat, P.N.; Gupta, S.K.; Ramana Murthy, P.V.

    1984-01-01

    A 24 hr emission variability of the Crab pulsar was examined. The data were gathered in the energy range up to 500 GeV using the Oota Atmospheric Cerenkov array. Analysis proceeded in terms of one second curves with retention of only those data within 5 sigma of the nominal values. The mean time between events was about 125 msec, while some microbursts occurred at a rate of one per 0.5 msec and could happen twice within a minute (macroburst). A coincidence of pulse occurrence and phase was noted. Phasograms were generated for the events coming from the Crab pulsar, whichmore » displayed peak emissions for only 0.0001 of the observing time. It is concluded that traditional averaging analysis can mask periods of intense emissions. 7 references.« less

  8. Predicting the Occurrence of Oxygenation Impairment in Patients with Type-B Acute Aortic Dissection

    PubMed Central

    Tomita, Kazunori; Hata, Noritake; Kobayashi, Nobuaki; Shinada, Takuro; Shirakabe, Akihiro

    2014-01-01

    Complicated respiratory failure requiring mechanical ventilation in patients with type-B acute aortic dissection (AAD) has been previously reported, and inflammatory reactions have been found to be associated with the occurrence of oxygenation impairment (OI). However, the possibility of predicting the occurrence of OI in patients with type-B AAD has not yet been evaluated. This study was performed to investigate the possibility of predicting the occurrence of OI in type-B AAD. In this study, 79 type-B AAD patients were enrolled to investigate the possibility of predicting the occurrence of OI. OI was defined as Po 2/Fio 2 ≤ 200. Patient characteristics, type of AAD, vital signs on admission, and the presence of inflammatory reactions obtained on admission day were evaluated. OI occurred in 39 patients (49%) on hospital day 2.5 ± 1.4 on average. Younger age, male gender, nonslender frame (body mass index ≥ 22 kg/m2), a relatively high maximum body temperature on the admission day (≥ 36.5°C), DeBakey IIIb type, patent false lumen, and lower Po 2/Fio 2 on admission were found to be associated with the occurrence of OI. Multivariate analysis revealed that nonslender frame, relatively high body temperature on the admission day, and lower Po 2/Fio 2 on admission were reliable for predicting the occurrence of oxygen impairment. The occurrence of OI in type-B AAD can be predicted in the clinical setting. PMID:24627618

  9. Neural pulse frequency modulation of an exponentially correlated Gaussian process

    NASA Technical Reports Server (NTRS)

    Hutchinson, C. E.; Chon, Y.-T.

    1976-01-01

    The effect of NPFM (Neural Pulse Frequency Modulation) on a stationary Gaussian input, namely an exponentially correlated Gaussian input, is investigated with special emphasis on the determination of the average number of pulses in unit time, known also as the average frequency of pulse occurrence. For some classes of stationary input processes where the formulation of the appropriate multidimensional Markov diffusion model of the input-plus-NPFM system is possible, the average impulse frequency may be obtained by a generalization of the approach adopted. The results are approximate and numerical, but are in close agreement with Monte Carlo computer simulation results.

  10. Accounting for Occurrences: A New View of the Use of Contingency Information in Causal Judgment

    ERIC Educational Resources Information Center

    White, Peter A.

    2008-01-01

    When people make causal judgments from contingency information, a principal aim is to account for occurrences of the outcome. When 2 causes are under consideration, the capacity of either to account for occurrences is judged from how likely the cause is to be present when the outcome occurs and from the rate at which the outcome occurs when that…

  11. The effect of high medical expenses on household income in South Korea: a longitudinal study using propensity score matching.

    PubMed

    Choi, Jae Woo; Park, Eun Cheol; Yoo, Ki Bong; Lee, Sang Gyu; Jang, Sung In; Kim, Tae Hyun

    2015-09-10

    Almost 97% of the Korean population is covered by National Health Insurance and are entitled to receive the same level of insurance benefits, regardless of how much each enrollee contributes to the system. However, the percentage of out-of-pocket payments is still high. This study examines whether the incurrence of high medical expenses affects household income. We use the Korea Welfare Panel and select 4,962 households to measure repeatedly over 5 years. Using propensity score matching, we set households with medical expenses of three times the annual average as "occurrence households" while "non-occurrence households" are those below the cut-off but with all other factors, such as income, held constant. We analyze whether the income of occurrence households differs significantly from the comparison group using a linear mixed effect model. After the occurrence of high medical expenditure, occurrence households (n = 825) had US$ 1,737 less income than non-occurrence households. In addition, the income of households (n = 200) that incurred high medical costs repeatedly for 2 years was US$ 3,598 lower than the non-occurrence group. Although it is important for the government to focus on medical assistance for households that have medical expense burdens, it needs to consider providing income indemnity insurance to protect them.

  12. A low computation cost method for seizure prediction.

    PubMed

    Zhang, Yanli; Zhou, Weidong; Yuan, Qi; Wu, Qi

    2014-10-01

    The dynamic changes of electroencephalograph (EEG) signals in the period prior to epileptic seizures play a major role in the seizure prediction. This paper proposes a low computation seizure prediction algorithm that combines a fractal dimension with a machine learning algorithm. The presented seizure prediction algorithm extracts the Higuchi fractal dimension (HFD) of EEG signals as features to classify the patient's preictal or interictal state with Bayesian linear discriminant analysis (BLDA) as a classifier. The outputs of BLDA are smoothed by a Kalman filter for reducing possible sporadic and isolated false alarms and then the final prediction results are produced using a thresholding procedure. The algorithm was evaluated on the intracranial EEG recordings of 21 patients in the Freiburg EEG database. For seizure occurrence period of 30 min and 50 min, our algorithm obtained an average sensitivity of 86.95% and 89.33%, an average false prediction rate of 0.20/h, and an average prediction time of 24.47 min and 39.39 min, respectively. The results confirm that the changes of HFD can serve as a precursor of ictal activities and be used for distinguishing between interictal and preictal epochs. Both HFD and BLDA classifier have a low computational complexity. All of these make the proposed algorithm suitable for real-time seizure prediction. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. T he Analysis of the seasonal variations of equatorial plasma bubble, occurrence observed from Oukaimeden Observatory, Morroco

    NASA Astrophysics Data System (ADS)

    Amine, Lagheryeb; Zouhair, Benkhaldoun; Jonathan, Makela; Mohamed, Kaab; Aziza, Bounhir; Brian, Hardin; Dan, Fisher; Tmuthy, Duly

    2016-04-01

    T he Analysis of the seasonal variations of equatorial plasma bubble, occurrence using the 630.0 nm airglow images collected by the PICASSO imager deployed at the Oukkaimden observatory in Morocco. Data have been taken since November 2013 to december 2015. We show the monthly average of appearance of EPBs. A maximum probability for bubble development is seen in the data in January and between late February and early March. We also observe that there are a maximum period of appearance where the plasma is observed (3-5 nights successivies) and we will discuss its connection with the solar activity in storm time. Future analysis will compare the probability of bubble occurrence in our site with the data raised in other observation sites.

  14. 47 CFR 64.1900 - Nondominant interexchange carrier certifications regarding geographic rate averaging and rate...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certifications regarding geographic rate averaging and rate integration requirements. 64.1900 Section 64.1900... Rate Averaging and Rate Integration Requirements § 64.1900 Nondominant interexchange carrier certifications regarding geographic rate averaging and rate integration requirements. (a) A nondominant provider...

  15. 47 CFR 64.1900 - Nondominant interexchange carrier certifications regarding geographic rate averaging and rate...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certifications regarding geographic rate averaging and rate integration requirements. 64.1900 Section 64.1900... Rate Averaging and Rate Integration Requirements § 64.1900 Nondominant interexchange carrier certifications regarding geographic rate averaging and rate integration requirements. (a) A nondominant provider...

  16. 47 CFR 64.1900 - Nondominant interexchange carrier certifications regarding geographic rate averaging and rate...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certifications regarding geographic rate averaging and rate integration requirements. 64.1900 Section 64.1900... Rate Averaging and Rate Integration Requirements § 64.1900 Nondominant interexchange carrier certifications regarding geographic rate averaging and rate integration requirements. (a) A nondominant provider...

  17. 47 CFR 64.1900 - Nondominant interexchange carrier certifications regarding geographic rate averaging and rate...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... certifications regarding geographic rate averaging and rate integration requirements. 64.1900 Section 64.1900... Rate Averaging and Rate Integration Requirements § 64.1900 Nondominant interexchange carrier certifications regarding geographic rate averaging and rate integration requirements. (a) A nondominant provider...

  18. 47 CFR 64.1900 - Nondominant interexchange carrier certifications regarding geographic rate averaging and rate...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... certifications regarding geographic rate averaging and rate integration requirements. 64.1900 Section 64.1900... Rate Averaging and Rate Integration Requirements § 64.1900 Nondominant interexchange carrier certifications regarding geographic rate averaging and rate integration requirements. (a) A nondominant provider...

  19. Negative-Pressure Wound Therapy in the Management of High-Grade Ventral Hernia Repairs.

    PubMed

    Rodriguez-Unda, Nelson; Soares, Kevin C; Azoury, Saïd C; Baltodano, Pablo A; Hicks, Caitlin W; Burce, Karen K; Cornell, Peter; Cooney, Carisa M; Eckhauser, Frederic E

    2015-11-01

    Despite improved operative techniques, open ventral hernia repair (VHR) surgery in high-risk, potentially contaminated patients remains challenging. As previously reported by our group, the use of a modified negative-pressure wound therapy system (hybrid-VAC or HVAC) in patients with grade 2 hernias is associated with lower surgical site occurrence (SSO) and surgical site infection (SSI) rates. Accordingly, the authors aim to evaluate whether the HVAC would similarly improve surgical site outcomes following VHR in patients with grade 3 hernias. A 4-year retrospective review (2011-2014) was conducted of all consecutive, modified ventral hernia working group (VHWG) grade 3 hernia repairs with HVAC closure performed by a single surgeon (FEE) at a single institution. Operative data and 90-day outcomes were evaluated. Overall outcomes (e.g., recurrence, reoperation, mortality) were reviewed for the study group. A total of 117 patients with an average age of 56.7 ± 11.9 years were classified as grade 3 hernias and underwent open VHR with subsequent HVAC closure. Fifty patients were male (42.7 %), the mean BMI was 35.2 (±9.5), and 60.7 % had a history of prior hernia repair. The average fascial defect size was 201.5 (±167.3) cm(2) and the mean length of stay was 14.2 (±9.3) days. Ninety-day outcomes showed an SSO rate of 20.7 % and an SSI rate of 5.2 %. The overall hernia recurrence rate was 4.2 % (n=6) with a mean follow-up of 11 ± 7.3 months. Modified VHWG grade 3 ventral hernias are associated with significant morbidity. In our series utilizing the HVAC system after VHR, the observed rate of SSO and SSI compared favorably to reported series. Further prospective cost-effective studies are warranted to validate these findings.

  20. Spatial correlation of hydrometeor occurrence, reflectivity, and rain rate from CloudSat

    NASA Astrophysics Data System (ADS)

    Marchand, Roger

    2012-03-01

    This paper examines the along-track vertical and horizontal structure of hydrometeor occurrence, reflectivity, and column rain rate derived from CloudSat. The analysis assumes hydrometeors statistics in a given region are horizontally invariant, with the probability of hydrometeor co-occurrence obtained simply by determining the relative frequency at which hydrometeors can be found at two points (which may be at different altitudes and offset by a horizontal distance, Δx). A correlation function is introduced (gamma correlation) that normalizes hydrometeor co-occurrence values to the range of 1 to -1, with a value of 0 meaning uncorrelated in the usual sense. This correlation function is a generalization of the alpha overlap parameter that has been used in recent studies to describe the overlap between cloud (or hydrometeor) layers. Examples of joint histograms of reflectivity at two points are also examined. The analysis shows that the traditional linear (or Pearson) correlation coefficient provides a useful one-to-one measure of the strength of the relationship between hydrometeor reflectivity at two points in the horizontal (that is, two points at the same altitude). While also potentially useful in the vertical direction, the relationship between reflectivity values at different altitudes is not as well described by the linear correlation coefficient. The decrease in correlation of hydrometeor occurrence and reflectivity with horizontal distance, as well as precipitation occurrence and column rain rate, can be reasonably well fit with a simple two-parameter exponential model. In this paper, the North Pacific and tropical western Pacific are examined in detail, as is the zonal dependence.

  1. Climatology of the Occurrence Rate and Amplitudes of Local Time Distinguished Equatorial Plasma Depletions Observed by Swarm Satellite

    NASA Astrophysics Data System (ADS)

    Wan, Xin; Xiong, Chao; Rodriguez-Zuluaga, Juan; Kervalishvili, Guram N.; Stolle, Claudia; Wang, Hui

    2018-04-01

    In this study, we developed an autodetection technique for the equatorial plasma depletions (EPDs) and their occurrence and depletion amplitudes based on in situ electron density measurements gathered by Swarm A satellite. For the first time, comparisons are made among the detected EPDs and their amplitudes with the loss of Global Positioning System (GPS) signal of receivers onboard Swarm A, and the Swarm Level-2 product, Ionospheric Bubble Index (IBI). It has been found that the highest rate of EPD occurrence takes place generally between 2200 and 0000 magnetic local time (MLT), in agreement with the IBI. However, the largest amplitudes of EPD are detected earlier at about 1900-2100 MLT. This coincides with the moment of higher background electron density and the largest occurrence of GPS signal loss. From a longitudinal perspective, the higher depletion amplitude is always witnessed in spatial bins with higher background electron density. At most longitudes, the occurrence rate of postmidnight EPDs is reduced compared to premidnight ones; while more postmidnight EPDs are observed at African longitudes. CHAMP observations confirm this point regardless of high or low solar activity condition. Further by comparing with previous studies and the plasma vertical drift velocity from ROCSAT-1, we suggest that while the F region vertical plasma drift plays a key role in dominating the occurrence of EPDs during premidnight hours, the postmidnight EPDs are the combined results from the continuing of former EPDs and newborn EPDs, especially during June solstice. And these newborn EPDs during postmidnight hours seem to be less related to the plasma vertical drift.

  2. Satellite observations for describing fire patterns and climate-related fire drivers in the Brazilian savannas

    NASA Astrophysics Data System (ADS)

    Verola Mataveli, Guilherme Augusto; Siqueira Silva, Maria Elisa; Pereira, Gabriel; da Silva Cardozo, Francielle; Shinji Kawakubo, Fernando; Bertani, Gabriel; Cezar Costa, Julio; de Cássia Ramos, Raquel; Valéria da Silva, Viviane

    2018-01-01

    In the Brazilian savannas (Cerrado biome) fires are natural and a tool for shifting land use; therefore, temporal and spatial patterns result from the interaction of climate, vegetation condition and human activities. Moreover, orbital sensors are the most effective approach to establish patterns in the biome. We aimed to characterize fire, precipitation and vegetation condition regimes and to establish spatial patterns of fire occurrence and their correlation with precipitation and vegetation condition in the Cerrado. The Cerrado was first and second biome for the occurrence of burned areas (BA) and hotspots, respectively. Occurrences are higher during the dry season and in the savanna land use. Hotspots and BA tend to decrease, and concentrate in the north, but more intense hotspots are not necessarily located where concentration is higher. Spatial analysis showed that averaged and summed values can hide patterns, such as for precipitation, which has the lowest average in August, but minimum precipitation in August was found in 7 % of the Cerrado. Usually, there is a 2-3-month lag between minimum precipitation and maximum hotspots and BA, while minimum VCI and maximum hotspots and BA occur in the same month. Hotspots and BA are better correlated with VCI than precipitation, qualifying VCI as an indicator of the susceptibility of vegetation to ignition.

  3. Spatial patterns of frequent floods in Switzerland

    NASA Astrophysics Data System (ADS)

    Schneeberger, Klaus; Rössler, Ole; Weingartner, Rolf

    2017-04-01

    Information about the spatial characteristics of high and extreme streamflow is often needed for an accurate analysis of flood risk and effective co-ordination of flood related activities, such as flood defence planning. In this study we analyse the spatial dependence of frequent floods in Switzerland across different scales. Firstly, we determine the average length of high and extreme flow events for 56 runoff time series of Swiss rivers. Secondly, a dependence measure expressing the probability that streamflow peaks are as high as peaks at a conditional site is used to describe and map the spatial extend of joint occurrence of frequent floods across Switzerland. Thirdly, we apply a cluster analysis to identify groups of sites that are likely to react similarly in terms of joint occurrence of high flow events. The results indicate that a time interval with a length of 3 days seems to be most appropriate to characterise the average length of high streamflow events across spatial scales. In the main Swiss basins, high and extreme streamflows were found to be asymptotically independent. In contrast, at the meso-scale distinct flood regions, which react similarly in terms of occurrence of frequent flood, were found. The knowledge about these regions can help to optimise flood defence planning or to estimate regional flood risk properly.

  4. Statistical study of auroral omega bands

    NASA Astrophysics Data System (ADS)

    Partamies, Noora; Weygand, James M.; Juusola, Liisa

    2017-09-01

    The presence of very few statistical studies on auroral omega bands motivated us to test-use a semi-automatic method for identifying large-scale undulations of the diffuse aurora boundary and to investigate their occurrence. Five identical all-sky cameras with overlapping fields of view provided data for 438 auroral omega-like structures over Fennoscandian Lapland from 1996 to 2007. The results from this set of omega band events agree remarkably well with previous observations of omega band occurrence in magnetic local time (MLT), lifetime, location between the region 1 and 2 field-aligned currents, as well as current density estimates. The average peak emission height of omega forms corresponds to the estimated precipitation energies of a few keV, which experienced no significant change during the events. Analysis of both local and global magnetic indices demonstrates that omega bands are observed during substorm expansion and recovery phases that are more intense than average substorm expansion and recovery phases in the same region. The omega occurrence with respect to the substorm expansion and recovery phases is in a very good agreement with an earlier observed distribution of fast earthward flows in the plasma sheet during expansion and recovery phases. These findings support the theory that omegas are produced by fast earthward flows and auroral streamers, despite the rarity of good conjugate observations.

  5. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly.

    PubMed

    Chen, Liwei; Zhang, Zhenzhen; Chen, Wen; Whelton, Paul K; Appel, Lawrence J

    2016-07-01

    To determine the effect of sodium (Na) reduction on occurrence of headaches. In the Trial of Nonpharmacologic Interventions in the Elderly, 975 men and woman (aged 60-80 years) with hypertension were randomized to a Na-reduction intervention or control group and were followed for up to 36 months. The study was conducted between 1992 and 1995 at 4 clinical centers (Johns Hopkins University, Wake Forest University School of Medicine, Robert Wood Johnson Medical School, and the University of Tennessee). Mean difference in Na excretion between the Na-reduction intervention and control group was significant at each follow-up visit (P < .001) with an average difference of 38.8 millimoles per 24 hours. The occurrence of headaches was significantly lower in the Na-reduction intervention group (10.5%) compared with control (14.3%) with a hazard ratio of 0.59 (95% confidence interval = 0.40, 0.88; P = .009). The risk of headaches was significantly associated with average level of Na excretion during follow-up, independent of most recent blood pressure. The relationship appeared to be nonlinear with a spline relationship and a knot at 150 millimoles per 24 hours. Reduced sodium intake, currently recommended for blood pressure control, may also reduce the occurrence of headaches in older persons with hypertension.

  6. On statistical irregularity of stratospheric warming occurrence during northern winters

    NASA Astrophysics Data System (ADS)

    Savenkova, Elena N.; Gavrilov, Nikolai M.; Pogoreltsev, Alexander I.

    2017-10-01

    Statistical analysis of dates of warming events observed during the years 1981-2016 at different stratospheric altitudes reveals their non-uniform distributions during northern winter months with maxima at the beginning of January, at the end of January - beginning of February and at the end of February. Climatology of zonal-mean zonal wind, deviations of temperature from its winter-averaged values, and planetary wave (PW) characteristics at high and middle northern latitudes in the altitude range from the ground up to 60 km is studied using the database of meteorological reanalysis MERRA. Climatological temperature deviations averaged over the 60-90°N latitudinal bands reveal cooler and warmer layers descending due to seasonal changes during the polar night. PW amplitudes and upward Eliassen-Palm fluxes averaged over 36 years have periodical maxima with the main maximum at the beginning of January at altitudes 40-50 km. During the above-mentioned intervals of more frequent occurrence of stratospheric warming events, maxima of PW amplitudes and Eliassen-Palm fluxes, also minima of eastward winds in the high-latitude northern stratosphere have been found. Climatological intra-seasonal irregularities of stratospheric warming dates could indicate reiterating phases of stratospheric vacillations in different years.

  7. The Relationship between Occurrence Timing of Dispensing Errors and Subsequent Danger to Patients under the Situation According to the Classification of Drugs by Efficacy.

    PubMed

    Tsuji, Toshikazu; Nagata, Kenichiro; Kawashiri, Takehiro; Yamada, Takaaki; Irisa, Toshihiro; Murakami, Yuko; Kanaya, Akiko; Egashira, Nobuaki; Masuda, Satohiro

    2016-01-01

    There are many reports regarding various medical institutions' attempts at the prevention of dispensing errors. However, the relationship between occurrence timing of dispensing errors and subsequent danger to patients has not been studied under the situation according to the classification of drugs by efficacy. Therefore, we analyzed the relationship between position and time regarding the occurrence of dispensing errors. Furthermore, we investigated the relationship between occurrence timing of them and danger to patients. In this study, dispensing errors and incidents in three categories (drug name errors, drug strength errors, drug count errors) were classified into two groups in terms of its drug efficacy (efficacy similarity (-) group, efficacy similarity (+) group), into three classes in terms of the occurrence timing of dispensing errors (initial phase errors, middle phase errors, final phase errors). Then, the rates of damage shifting from "dispensing errors" to "damage to patients" were compared as an index of danger between two groups and among three classes. Consequently, the rate of damage in "efficacy similarity (-) group" was significantly higher than that in "efficacy similarity (+) group". Furthermore, the rate of damage is the highest in "initial phase errors", the lowest in "final phase errors" among three classes. From the results of this study, it became clear that the earlier the timing of dispensing errors occurs, the more severe the damage to patients becomes.

  8. [International focuses in the studies of chronic pelvic pain syndrome: A social network analysis].

    PubMed

    Wen, Li-Jie; Pan, Xian-Wei; Yang, Bo

    2016-10-01

    To analyze the internationally published literature relevant to chronic pelvic pain syndrome (CPPS) using bibliometrics and social network analysis, and investigate the current status and focuses of CPPS studies. We identified 692 publications on CPPS by searching PubMed up to December 2015, extracted their subject headings, calculated the frequencies of the headings, and constructed a co-occurrence network of the high-frequency (≥10) subject headings. Then we studied the features and structure of the co-occurrence network by analyzing its attributes and topological structure. The density of the constructed co-occurrence network was 0.111, with an average distance of 2.886 and a clustering coefficient of 0.685. Its low density, long average distance and high clustering coefficient indicated that it was a sparse network, with a slow speed of information spreading among nodes but a strong potential coherence, which suggested that the current topics in the study of CPPS were scattered and weakly correlated, with a high possibility of being integrated. Based on the topological structure of the co-occurrence network, the topics in the study of CPPS were divided into six aspects: diagnosis and classification, drug therapy, treatment, etiology, microbiology, psychology, and epidemiology, the more important of which were diagnosis and classification, drug therapy, treatment and etiology. A system has been formed in the studies of CPPS, focusing on the diagnosis, drug therapy, and etiology of the disease. However, the research topics are relatively scattered and frequently repeated. Therefore, more attention should be paid to the macrocosmic guidance and rational coordination of the researches on CPPS.

  9. Analysis of weather changes in the region of Surabaya in 2015 and 2016 using water vapor data from GPS and Terra MODIS satellite image

    NASA Astrophysics Data System (ADS)

    Cahyadi, M. N.; Audah, S.; Mutia, N.; Aliyan, S. A.

    2017-07-01

    Sea surface temperature conditions in the territorial waters of Indonesia can be used as one indicator of a lot or least the content of water vapor in the atmosphere. It is closely related to the process of cloud formation in the region of Indonesia. Surabaya is the capital of the Indonesia's second largest potential for the occurrence of global warming due to climate change around the region. Global warming has the consequence of occurrence of climate variability, with marked by changes in temperature, and rainfall, as well as runoff of water. Monitoring the space-based Global Positioning System (GPS) and remote sensing satellite data such as Terra MODIS can be used in the field of meteorology. That is to measured the level of water vapor globally, with the approach of the amount of precipitable water vapor (PWV) in the atmosphere layer. It can be seen humidity conditions and the potential occurrence of rainfall in an area. The PWV value obtained from GPS processing had range 25.13 mm - 32.87 mm; average value is 27.38 mm and standard deviation is 2.018 mm. Based on the diurnal variation of the PWV GPS indicates that the climatic conditions in the area of Surabaya in 2015 showed the dry season, this is because the average values of PWV pretty low that occurred in July-September. But in September 2015 the PWV value occurrence an increase in water vapor and can be estimated that in the next month will be approaching rainy season.

  10. Year to year variation of rainfall rate and rainfall regime in Ota, southwest Nigeria for the year 2012 to 2015

    NASA Astrophysics Data System (ADS)

    Omotosho, T. V.; Ometan, O. O.; Akinwumi, S. A.; Adewusi, O. M.; Boyo, A. O.; Singh, M. S. J.

    2017-05-01

    The tropics is characterized to have convective type of rainfall which has high occurrence of rainfall compared to the temperate regions of the world. In this paper, the accumulation of rainfall in Ota, Southwest, Nigeria (6° 42 N, 3° 14 E) has been analysed to present the one-minute rainfall rate and the predominant type of rainfall. Four years’ data used for this study was taken using the Davis Wireless vantage Pro2 weather station at Covenant University, Ota, Ogun State. The data collected were used to analyse the one-minute rainfall rate and different types of rainfall predominant in this region. For the prediction and modelling of rain attenuation at microwave frequencies for a region like the Nigeria at various percentage of time, one-minute rainfall rate is required. Nigeria falls into the P zone of 114 mm/hr. as per International Telecommunication Union - Recommendation (ITU-R). The analysis carried out indicated that the measured yearly averaged maximum one-minute rainfall rate for 2012, 2013, 2014 and 2015 are 157.7 mm/h, 148.0 mm/h, 241.2 mm/h and 157.3 mm/h respectively. It also indicated that the drizzle type of rainfall is predominant in contrast to established fact that thunderstorm occurs more in the tropics.

  11. Preferred Hosts for Short-Period Exoplanets

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2015-12-01

    In an effort to learn more about how planets form around their host stars, a team of scientists has analyzed the population of Kepler-discovered exoplanet candidates, looking for trends in where theyre found.Planetary OccurrenceSince its launch in 2009, Kepler has found thousands of candidate exoplanets around a variety of star types. Especially intriguing is the large population of super-Earths and mini-Neptunes planets with masses between that of Earth and Neptune that have short orbital periods. How did they come to exist so close to their host star? Did they form in situ, or migrate inwards, or some combination of both processes?To constrain these formation mechanisms, a team of scientists led by Gijs Mulders (University of Arizona and NASAs NExSS coalition) analyzed the population of Kepler planet candidates that have orbital periods between 2 and 50 days.Mulders and collaborators used statistical reconstructions to find the average number of planets, within this orbital range, around each star in the Kepler field. They then determined how this planet occurrence rate changed for different spectral types and therefore the masses of the host stars: do low-mass M-dwarf stars host more or fewer planets than higher-mass, main-sequence F, G, or K stars?Challenging ModelsAuthors estimates for the occurrence rate for short-period planets of different radii around M-dwarfs (purple) and around F, G, and K-type stars (blue). [Mulders et al. 2015]The team found that M dwarfs, compared to F, G, or K stars, host about half as many large planets with orbital periods of P 50 days. But, surprisingly, they host significantly more small planets, racking up an average of 3.5 times the number of planets in the size range of 12.8 Earth-radii.Could it be that M dwarfs have a lower total mass of planets, but that mass is distributed into more, smaller planets? Apparently not: the authors show that the mass of heavy elements trapped in short-orbital-period planets is higher for M dwarfs than for the larger F, G and K stars.All of this goes contrary to expectation, because we know that protostellar disks, from which planets form, are more massive around larger-mass stars. So why is there more heavy-element mass trapped in planetary systems with low stellar mass?This outcome isnt predicted by either in situ or migration planet formation theories. The authors instead propose that the distribution could be explained if the inward drift of planetary building blocks either dust grains or protoplanets turns out to be more efficient around lower-mass stars.CitationGijs D. Mulders et al 2015 ApJ 814 130. doi:10.1088/0004-637X/814/2/130

  12. Acquisition of peak responding: what is learned?

    PubMed

    Balci, Fuat; Gallistel, Charles R; Allen, Brian D; Frank, Krystal M; Gibson, Jacqueline M; Brunner, Daniela

    2009-01-01

    We investigated how the common measures of timing performance behaved in the course of training on the peak procedure in C3H mice. Following fixed interval (FI) pre-training, mice received 16 days of training in the peak procedure. The peak time and spread were derived from the average response rates while the start and stop times and their relative variability were derived from a single-trial analysis. Temporal precision (response spread) appeared to improve in the course of training. This apparent improvement in precision was, however, an averaging artifact; it was mediated by the staggered appearance of timed stops, rather than by the delayed occurrence of start times. Trial-by-trial analysis of the stop times for individual subjects revealed that stops appeared abruptly after three to five sessions and their timing did not change as training was prolonged. Start times and the precision of start and stop times were generally stable throughout training. Our results show that subjects do not gradually learn to time their start or stop of responding. Instead, they learn the duration of the FI, with robust temporal control over the start of the response; the control over the stop of response appears abruptly later.

  13. Acquisition of peak responding: What is learned?

    PubMed Central

    Balci, Fuat; Gallistel, Charles R.; Allen, Brian D.; Frank, Krystal M.; Gibson, Jacqueline M.; Brunner, Daniela

    2009-01-01

    We investigated how the common measures of timing performance behaved in the course of training on the peak procedure in C3H mice. Following fixed interval (FI) pre-training, mice received 16 days of training in the peak procedure. The peak time and spread were derived from the average response rates while the start and stop times and their relative variability were derived from a single-trial analysis. Temporal precision (response spread) appeared to improve in the course of training. This apparent improvement in precision was, however, an averaging artifact; it was mediated by the staggered appearance of timed stops, rather than by the delayed occurrence of start times. Trial-by-trial analysis of the stop times for individual subjects revealed that stops appeared abruptly after three to five sessions and their timing did not change as training was prolonged. Start times and the precision of start and stop times were generally stable throughout training. Our results show that subjects do not gradually learn to time their start or stop of responding. Instead, they learn the duration of the FI, with robust temporal control over the start of the response; the control over the stop of response appears abruptly later. PMID:18950695

  14. Invasive Cancer Incidence, 2004–2013, and Deaths, 2006–2015, in Nonmetropolitan and Metropolitan Counties — United States

    PubMed Central

    Anderson, Robert N.; Thomas, Cheryll C.; Massetti, Greta M.; Peaker, Brandy; Richardson, Lisa C.

    2017-01-01

    Problem/Condition Previous reports have shown that persons living in nonmetropolitan (rural or urban) areas in the United States have higher death rates from all cancers combined than persons living in metropolitan areas. Disparities might vary by cancer type and between occurrence and death from the disease. This report provides a comprehensive assessment of cancer incidence and deaths by cancer type in nonmetropolitan and metropolitan counties. Reporting Period 2004–2015. Description of System Cancer incidence data from CDC’s National Program of Cancer Registries and the National Cancer Institute’s Surveillance, Epidemiology, and End Results program were used to calculate average annual age-adjusted incidence rates for 2009–2013 and trends in annual age-adjusted incidence rates for 2004–2013. Cancer mortality data from the National Vital Statistics System were used to calculate average annual age-adjusted death rates for 2011–2015 and trends in annual age-adjusted death rates for 2006–2015. For 5-year average annual rates, counties were classified into four categories (nonmetropolitan rural, nonmetropolitan urban, metropolitan with population <1 million, and metropolitan with population ≥1 million). For the trend analysis, which used annual rates, these categories were combined into two categories (nonmetropolitan and metropolitan). Rates by county classification were examined by sex, age, race/ethnicity, U.S. census region, and cancer site. Trends in rates were examined by county classification and cancer site. Results During the most recent 5-year period for which data were available, nonmetropolitan rural areas had lower average annual age-adjusted cancer incidence rates for all anatomic cancer sites combined but higher death rates than metropolitan areas. During 2006–2015, the annual age-adjusted death rates for all cancer sites combined decreased at a slower pace in nonmetropolitan areas (-1.0% per year) than in metropolitan areas (-1.6% per year), increasing the differences in these rates. In contrast, annual age-adjusted incidence rates for all cancer sites combined decreased approximately 1% per year during 2004–2013 both in nonmetropolitan and metropolitan counties. Interpretation This report provides the first comprehensive description of cancer incidence and mortality in nonmetropolitan and metropolitan counties in the United States. Nonmetropolitan rural counties had higher incidence of and deaths from several cancers related to tobacco use and cancers that can be prevented by screening. Differences between nonmetropolitan and metropolitan counties in cancer incidence might reflect differences in risk factors such as cigarette smoking, obesity, and physical inactivity, whereas differences in cancer death rates might reflect disparities in access to health care and timely diagnosis and treatment. Public Health Action Many cancer cases and deaths could be prevented, and public health programs can use evidence-based strategies from the U.S. Preventive Services Task Force and Advisory Committee for Immunization Practices (ACIP) to support cancer prevention and control. The U.S. Preventive Services Task Force recommends population-based screening for colorectal, female breast, and cervical cancers among adults at average risk for these cancers and for lung cancer among adults at high risk; screening adults for tobacco use and excessive alcohol use, offering counseling and interventions as needed; and using low-dose aspirin to prevent colorectal cancer among adults considered to be at high risk for cardiovascular disease based on specific criteria. ACIP recommends vaccination against cancer-related infectious diseases including human papillomavirus and hepatitis B virus. The Guide to Community Preventive Services describes program and policy interventions proven to increase cancer screening and vaccination rates and to prevent tobacco use, excessive alcohol use, obesity, and physical inactivity. PMID:28683054

  15. The relationship of large fire occurrence with drought and fire danger indices in the western USA, 1984-2008: The role of temporal scale

    Treesearch

    Karin L. Riley; John T. Abatzoglou; Isaac C. Grenfell; Anna E. Klene; Faith Ann Heinsch

    2013-01-01

    The relationship between large fire occurrence and drought has important implications for fire prediction under current and future climates. This study’s primary objective was to evaluate correlations between drought and fire-danger- rating indices representing short- and long-term drought, to determine which had the strongest relationships with large fire occurrence...

  16. An Overview of Three-year JEM-GLIMS Nadir Observations of Lightning and TLEs

    NASA Astrophysics Data System (ADS)

    Sato, M.; Ushio, T.; Morimoto, T.; Adachi, T.; Kikuchi, H.; Suzuki, M.; Yamazaki, A.; Takahashi, Y.; Inan, U.; Linscott, I.; Hobara, Y.

    2015-12-01

    JEM-GLIMS nadir observations of lightning and TLEs at the ISS started from November 2012 and successfully ended on August 2015. For three-year observation period, JEM-GLIMS succeeded in detecting over 8,000 lightning events and 670 TLEs. The detected optical emissions of sprites showed clear horizontal displacement with the range of 10-20 km from the peak location of the +CG emissions and from the +CG locations detected by NLDN and WWLLN. Using VITF electric field waveform data, source locations of VHF pulses excited by the parent CG discharges are estimated. It is found that the possible VHF source locations were mostly located within the area of the parent lightning emissions. These facts may imply that the center region of the neutralized charge by CG discharges in the thundercloud located near the return stroke point and that the some seed conditions were established in advance at the sprite location before the occurrence of sprites. The global occurrence distributions and rates of lightning discharges and TLEs are also estimated. The estimated mean global occurrence rate of lightning discharges is ~1.5 events/s, which is smaller number than that derived from MicroLab-1/OTD and TRMM/LIS measurements. This may be originated in the fact that JEM-GLISM detected only intense lightning optical events due to the high threshold level for the event triggering. To the contrary, the estimated mean global occurrence rate of TLEs is ~9.8 events/min, which is two times higher than the ISUAL result. It is likely that JEM-GLIMS could detect dimmer optical emissions of TLEs than ISUAL since the distance between the JEM-GLIMS instruments and TLEs is much closer. At the presentation, we will summarize the results derived from three-year JEM-GLIMS nadir observations. We will discuss possible occurrence conditions of sprites, properties of global occurrence rates of lightning and TLEs, and their LT dependences more in detail.

  17. Climate analysis of tornadoes in China

    NASA Astrophysics Data System (ADS)

    Yao, Yeqing; Yu, Xiaoding; Zhang, Yijun; Zhou, Zijiang; Xie, Wusan; Lu, Yanyu; Yu, Jinlong; Wei, Lingxiang

    2015-06-01

    Based on analysis of historical tornado observation data provided by the primary network of national weather stations in China for the period from 1960 to 2009, it is found that most tornadoes in China (85%) occurred over plains. Specifically, large numbers of tornado occurrences are found in the Northeast Plain, the North China Plain, the middle-lower Yangtze Plain, and the Pearl River Delta Plain. A flat underlying surface is conducive to tornado occurrence, while the latitudal variation of tornado occurrence in China is not so obvious. Tornadoes mainly occur in summer, and the highest frequency is in July. Note that the beginning and the time span of tornado outbreaks are different in North and South China. Tornadoes occur during May-September in South China (south of 25°N), June-September in Northeast China (north of 40°N), July-September in the middle-lower Yangtze Plain, and July-August in North China (between 25° and 40°N). More than 80% of total tornadoes occurred during the above periods for the specific regions. The 1960s and 1970s have seen about twice the average number of tornadoes (7.5 times per year) compared to the mean for 1960-2009. The most frequent occurrence of tornado was in the early and mid 1960s; there were large fluctuations in the 1970s; and the number of tornadoes in the 1980s approached the 50-yr average. Tornado occurrences gradually decreased in the late 1980s, and an abrupt change with dramatic decrease occurred in 1994. The decrease in the tornado occurrence frequency is consistent with the simultaneous climatic change in the meteorological elements that are favorable for tornado formation. Tornado formation requires large vertical wind shear and sufficient atmospheric moisture content near the ground. Changes in the vertical wind shear at both 0-1 and 0-6 km appear to be one important factor that results in the decrease in tornado formation. The changing tendency of relative humidity also has contributed to the decrease in tornado formation in China.

  18. A prospective 8 week trial of nasal interfaces vs. a novel oral interface (Oracle) for treatment of obstructive sleep apnea hypopnea syndrome.

    PubMed

    Khanna, Ritu; Kline, Lewis R

    2003-07-01

    To compare efficacy, compliance rates, and side effects of a new strapless oral interface, the Oracle, with available nasal masks over 8 weeks of use for the treatment of obstructive sleep apnea hypopnea syndrome (OSAHS). A total of 38 patients with OSAHS (respiratory disturbance index (RDI) >/=15/h) were enrolled after the diagnostic polysomnogram for subsequent continuous positive airway pressure (CPAP) therapy. After randomization, therapeutic pressures during a titration study were determined for 21 patients in the oral group and 17 patients in the nasal group. Comparisons for nasal and oral interfaces were made for baseline patient characteristics, average hours of CPAP use, side effects from therapy, and among questionnaires evaluating patients' subjective responses to therapy at months 1 and 2. No significant difference was observed in the average hours of CPAP use between the oral (4.5+/-2.1; 5.5+/-2.6) and nasal groups (4.0+/-2.6; 4.8+/-2.5) for either month 1 or 2 (P>0.05). The dropout rates were similar for both groups after 8 weeks of therapy. However, patients in the nasal group had higher occurrences of side effects such as nasal congestion, dryness, and air leaks, whereas patients in the oral group experienced more oral dryness and gum pain. Oral delivery of CPAP with the Oracle is an effective and suitable alternative for patients with OSAHS.

  19. [Population in the northern border area. Urban dynamism and binational interrelation].

    PubMed

    Ham Chande, R

    1988-01-01

    The 3300 km border between Mexico and the US constitutes the geopolitical separation between an underdeveloped country on the 1 hand and 1 of the most technologically and economically powerful countries in the world on the other. The border region is characterized by the contrasts on either side of the border and by the strong interrelation between both sides. Vast streams of persons, merchandise, money, services, communications, and cultural influences flow from 1 side to the other. The border region as a seat of population has a recent history. The border was defined in near current form only in the mid-19th century, when the expansionist tendencies of the US encountered a vast area of very sparse population. In 1900, the principal localities of the border zone had only about 39,000 inhabitants, of whom fewer than 5000 lived west of Ciudad Juarez. Between 1910-20, the population of the border region increased from 53,000 to 96,000 as a result of migrants fleeing the ravages of the revolution. The population of the border region was estimated at 3.826 million in 1988, resulting from rates of growth above Mexico's national average. Settlement in the area has depended on events and conditions in Mexico and on such US occurrences as Prohibition, the Great Depression, the 2nd World War, the Bracero program, and the Program of Border Industrialization. 82% of the border population lives in urban zones, partly because of lack of water. 80% of the urban population is concentrated in 6 cities, Juarez, Tijuana, Mexicali, Nuevo Laredo, Reynosa, and Matamoros. Much of the population of the 6 cities is composed of persons born elsewhere. The border area also has a large floating population of undocumented migrants in transit to or from the US. The high rates of urbanization and of binational interaction are reflected in demographic dynamics. In 1979, 71% of women in union in the border area vs 54% in the rest of Mexico had used contraception, and the infant mortality rate was 10% below the national average. In the 20-29 cohort there were 88 men per 100 women, reflecting male emigration and female inmigration. The rate of economic participation was higher than the national average, per capita production was greater, and unemployment rates were lower.

  20. [Maternal diabetes--normalized perinatal mortality, but still high fetal growth].

    PubMed

    Hellesen, H B; Vikane, E; Lie, R T; Irgens, L M

    1996-11-30

    Studies suggest that maternal diabetes can cause both placental insufficiency and exaggerated foetal growth. Pregnant mothers with diabetes have suffered high risk of losing their child. Data from the Medical Birth Registry of Norway show a decrease in the still birth rate from 16th week of gestation from 115.7 per 1,000 in 1967-75 to 12.8 in 1986-92 in the diabetes groups. The relative risks were 7.8 and 1.4 respectively for the two time periods. The early neonatal mortality rate decreased correspondingly. The proportion of Caesarean sections in mothers with diabetes, and the proportion of children with low birth weight or born prematurely also increased in the diabetes group. However, children in the diabetes group were on average still as big at gestational age in the most recent period as in the first period. Our data suggest that the improved metabolic control of maternal diabetes has reduced the occurrence and degree of placental insufficiency, with inherent decreases in mortality and risk of complications, but without reducing the foetal growth-stimulating effect of maternal diabetes.

  1. Nitrogen removal via nitrite in a partial nitrification sequencing batch biofilm reactor treating high strength ammonia wastewater and its greenhouse gas emission.

    PubMed

    Wei, Dong; Zhang, Keyi; Ngo, Huu Hao; Guo, Wenshan; Wang, Siyu; Li, Jibin; Han, Fei; Du, Bin; Wei, Qin

    2017-04-01

    In present study, the feasibility of partial nitrification (PN) process achievement and its greenhouse gas emission were evaluated in a sequencing batch biofilm reactor (SBBR). After 90days' operation, the average effluent NH 4 + -N removal efficiency and nitrite accumulation rate of PN-SBBR were high of 98.2% and 87.6%, respectively. Both polysaccharide and protein contents were reduced in loosely bound extracellular polymeric substances (LB-EPS) and tightly bound EPS (TB-EPS) during the achievement of PN-biofilm. Excitation-emission matrix spectra implied that aromatic protein-like, tryptophan protein-like and humic acid-like substances were the main compositions of both kinds of EPS in seed sludge and PN-biofilm. According to typical cycle, the emission rate of CO 2 had a much higher value than that of N 2 O, and their total amounts per cycle were 67.7 and 16.5mg, respectively. Free ammonia (FA) played a significant role on the inhibition activity of nitrite-oxidizing bacteria and the occurrence of nitrite accumulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Exploring exoplanet populations with NASA's Kepler Mission

    NASA Astrophysics Data System (ADS)

    Batalha, Natalie M.

    2014-09-01

    The Kepler Mission is exploring the diversity of planets and planetary systems. Its legacy will be a catalog of discoveries sufficient for computing planet occurrence rates as a function of size, orbital period, star type, and insolation flux. The mission has made significant progress toward achieving that goal. Over 3,500 transiting exoplanets have been identified from the analysis of the first 3 y of data, 100 planets of which are in the habitable zone. The catalog has a high reliability rate (85-90% averaged over the period/radius plane), which is improving as follow-up observations continue. Dynamical (e.g., velocimetry and transit timing) and statistical methods have confirmed and characterized hundreds of planets over a large range of sizes and compositions for both single- and multiple-star systems. Population studies suggest that planets abound in our galaxy and that small planets are particularly frequent. Here, I report on the progress Kepler has made measuring the prevalence of exoplanets orbiting within one astronomical unit of their host stars in support of the National Aeronautics and Space Administration's long-term goal of finding habitable environments beyond the solar system.

  3. Biogenic amine content, histamine-forming bacteria, and adulteration of pork in tuna sausage products.

    PubMed

    Kung, Hsien-Feng; Tsai, Yung-Hsiang; Chang, Shih-Chih; Hong, Tang-Yao

    2012-10-01

    Twenty-five tuna sausage products were purchased from retail markets in Taiwan. The rates of occurrence of biogenic amines, histamine-forming bacteria, and adulteration by pork and poultry were determined. The average content of various biogenic amines in all tested samples was less than 2.0 mg/100 g (<0.05 to 1.85 mg/100 g). Thirteen histamine-producing bacterial strains isolated from tested samples produced 12.1 to 1,261 ppm of histamine in Trypticase soy broth supplemented with 1.0% L-histidine. Among them, Raoultella ornithinolytica (one strain), Enterobacter aerogenes (one strain), and Staphylococcus pasteuri (two strains) were identified as prolific histamine formers. PCR assay revealed that the adulteration rates were 80% (20 of 25) and 4% (1 of 25) for pork and poultry, respectively, in tuna sausage. The fish species in the tuna sausage samples were identified as Thunnus albacares for 22 samples (88%), Thunnus alalunga for 1 sample (4%), and Thunnus thynnus for 1 sample (4%), whereas the remaining sample was identified as Makaira nigricans (blue marlin).

  4. Evidence of recent volcanic activity on the ultraslow-spreading Gakkel ridge.

    PubMed

    Edwards, M H; Kurras, G J; Tolstoy, M; Bohnenstiehl, D R; Coakley, B J; Cochran, J R

    2001-02-15

    Seafloor spreading is accommodated by volcanic and tectonic processes along the global mid-ocean ridge system. As spreading rate decreases the influence of volcanism also decreases, and it is unknown whether significant volcanism occurs at all at ultraslow spreading rates (<1.5 cm yr(-1)). Here we present three-dimensional sonar maps of the Gakkel ridge, Earth's slowest-spreading mid-ocean ridge, located in the Arctic basin under the Arctic Ocean ice canopy. We acquired this data using hull-mounted sonars attached to a nuclear-powered submarine, the USS Hawkbill. Sidescan data for the ultraslow-spreading (approximately 1.0 cm yr(-1)) eastern Gakkel ridge depict two young volcanoes covering approximately 720 km2 of an otherwise heavily sedimented axial valley. The western volcano coincides with the average location of epicentres for more than 250 teleseismic events detected in 1999, suggesting that an axial eruption was imaged shortly after its occurrence. These findings demonstrate that eruptions along the ultraslow-spreading Gakkel ridge are focused at discrete locations and appear to be more voluminous and occur more frequently than was previously thought.

  5. Exploring exoplanet populations with NASA's Kepler Mission.

    PubMed

    Batalha, Natalie M

    2014-09-02

    The Kepler Mission is exploring the diversity of planets and planetary systems. Its legacy will be a catalog of discoveries sufficient for computing planet occurrence rates as a function of size, orbital period, star type, and insolation flux. The mission has made significant progress toward achieving that goal. Over 3,500 transiting exoplanets have been identified from the analysis of the first 3 y of data, 100 planets of which are in the habitable zone. The catalog has a high reliability rate (85-90% averaged over the period/radius plane), which is improving as follow-up observations continue. Dynamical (e.g., velocimetry and transit timing) and statistical methods have confirmed and characterized hundreds of planets over a large range of sizes and compositions for both single- and multiple-star systems. Population studies suggest that planets abound in our galaxy and that small planets are particularly frequent. Here, I report on the progress Kepler has made measuring the prevalence of exoplanets orbiting within one astronomical unit of their host stars in support of the National Aeronautics and Space Administration's long-term goal of finding habitable environments beyond the solar system.

  6. Speech waveform perturbation analysis: a perceptual-acoustical comparison of seven measures.

    PubMed

    Askenfelt, A G; Hammarberg, B

    1986-03-01

    The performance of seven acoustic measures of cycle-to-cycle variations (perturbations) in the speech waveform was compared. All measures were calculated automatically and applied on running speech. Three of the measures refer to the frequency of occurrence and severity of waveform perturbations in special selected parts of the speech, identified by means of the rate of change in the fundamental frequency. Three other measures refer to statistical properties of the distribution of the relative frequency differences between adjacent pitch periods. One perturbation measure refers to the percentage of consecutive pitch period differences with alternating signs. The acoustic measures were tested on tape recorded speech samples from 41 voice patients, before and after successful therapy. Scattergrams of acoustic waveform perturbation data versus an average of perceived deviant voice qualities, as rated by voice clinicians, are presented. The perturbation measures were compared with regard to the acoustic-perceptual correlation and their ability to discriminate between normal and pathological voice status. The standard deviation of the distribution of the relative frequency differences was suggested as the most useful acoustic measure of waveform perturbations for clinical applications.

  7. Fuel processor temperature monitoring and control

    DOEpatents

    Keskula, Donald H.; Doan, Tien M.; Clingerman, Bruce J.

    2002-01-01

    In one embodiment, the method of the invention monitors one or more of the following conditions: a relatively low temperature value of the gas stream; a relatively high temperature value of the gas stream; and a rate-of-change of monitored temperature. In a preferred embodiment, the rate of temperature change is monitored to prevent the occurrence of an unacceptably high or low temperature condition. Here, at least two temperatures of the recirculating gas stream are monitored over a period of time. The rate-of-change of temperature versus time is determined. Then the monitored rate-of-change of temperature is compared to a preselected rate-of-change of value. The monitoring of rate-of-change of temperature provides proactive means for preventing occurrence of an unacceptably high temperature in the catalytic reactor.

  8. The Clinical and Economic Impact of Exacerbations of Chronic Obstructive Pulmonary Disease: A Cohort of Hospitalized Patients

    PubMed Central

    Blasi, Francesco; Cesana, Giancarlo; Conti, Sara; Chiodini, Virginio; Aliberti, Stefano; Fornari, Carla; Mantovani, Lorenzo Giovanni

    2014-01-01

    Background Chronic Obstructive Pulmonary Disease (COPD) is a common disease with significant health and economic consequences. This study assesses the burden of COPD in the general population, and the influence of exacerbations (E-COPD) on disease progression and costs. Methods This is a secondary data analysis of healthcare administrative databases of the region of Lombardy, in northern Italy. The study included ≥ 40 year-old patients hospitalized for a severe E-COPD (index event) during 2006. Patients were classified in relation to the number and type of E-COPD experienced in a three-year pre-index period. Subjects were followed up until December 31st, 2009, collecting data on healthcare resource use and vital status. Results 15857 patients were enrolled –9911 males, mean age: 76 years (SD 10). Over a mean follow-up time of 2.4 years (1.36), 81% of patients had at least one E-COPD with an annual rate of 3.2 exacerbations per person-year and an all-cause mortality of 47%. A history of exacerbation influenced the occurrence of new E-COPD and mortality after discharge for an E-COPD. On average, the healthcare system spent 6725€ per year per person (95%CI 6590–6863). Occurrence and type of exacerbations drove the direct healthcare cost. Less than one quarter of patients presented claims for pulmonary function tests. Conclusions COPD imposes a substantial burden on healthcare systems, mainly attributable to the type and occurrence of E-COPD, or in other words, to the exacerbator phenotypes. A more tailored approach to the management of COPD patients is required. PMID:24971791

  9. A new assessment method of outdoor tobacco smoke (OTS) exposure

    NASA Astrophysics Data System (ADS)

    Cho, Hyeri; Lee, Kiyoung

    2014-04-01

    Outdoor tobacco smoke (OTS) is concerned due to potential health effects. An assessment method of OTS exposure is needed to determine effects of OTS and validate outdoor smoking policies. The objective of this study was to develop a new method to assess OTS exposure. This study was conducted at 100 bus stops including 50 centerline bus stops and 50 roadside bus stops in Seoul, Korea. Using real-time aerosol monitor, PM2.5 was measured for 30 min at each bus stop in two seasons. ‘Peak analysis' method was developed to assess short term PM2.5 exposure by OTS. The 30-min average PM2.5 exposure at each bus stop was associated with season and bus stop location but not smoking activity. The PM2.5 peak occurrence rate by the peak analysis method was significantly associated with season, bus stop location, observed smoking occurrence, and the number of buses servicing a route. The PM2.5 peak concentration was significantly associated with season, smoking occurrence, and the number of buses servicing a route. When a smoker was standing still at the bus stop, magnitude of peak concentrations were significantly higher than when the smoker walking-through the bus stop. People were exposed to high short-term PM2.5 peak levels at bus stops, and the magnitude of peak concentrations were highest when a smoker was located close to the monitor. The magnitude of peak concentration was a good indicator helped distinguish nearby OTS exposure. Further research using ‘peak analysis' is needed to measure smoking-related exposure to PM2.5 in other outdoor locations.

  10. On numerical heat transfer characteristic study of flat surface subjected to variation in geometric thickness

    NASA Astrophysics Data System (ADS)

    Umair, Siddique Mohammed; Kolawale, Abhijeet Rangnath; Bhise, Ganesh Anurath; Gulhane, Nitin Parashram

    Thermal management in the looming world of electronic packaging system is the most prior and conspicuous issue as far as the working efficiency of the system is concerned. The cooling in such systems can be achieved by impinging air jet over the heat sink as jet impingement cooling is one of the cooling technologies which are widely studied now. Here the modulation in impinging and geometric parameters results in the establishment of the characteristic cooling rate over the target surface. The characteristic cooling curve actually resembles non-uniformity in cooling rate. This non-uniformity favors the area average heat dissipation rate. In order to study the non-uniformity in cooling characteristic, the present study takes an initiative in plotting the local Nusselt number magnitude against the non-dimensional radial distance of the different thickness of target surfaces. For this, the steady temperature distribution over the target surface under the impingement of air jet is being determined numerically. The work is completely inclined towards the determination of critical value of geometric thickness below which the non-uniformity in the Nusselt profile starts. This is done by numerically examining different target surfaces under constant Reynolds number and nozzle-target spacing. The occurrences of non-uniformity in Nusselt profile contributes to over a 42% enhancement in area average Nusselt magnitude. The critical value of characteristic thickness (t/d) reported in the present investigation approximate to 0.05. Below this value, the impingement of air jet generates a discrete pressure zones over the target surface in the form of pressure spots. As a result of this, the air flowing in contact with the target surface experiences a damping potential, in due of which it gets more time and contact with the surface to dissipate heat.

  11. Decline in temperature and humidity increases the occurrence of influenza in cold climate.

    PubMed

    Jaakkola, Kari; Saukkoriipi, Annika; Jokelainen, Jari; Juvonen, Raija; Kauppila, Jaana; Vainio, Olli; Ziegler, Thedi; Rönkkö, Esa; Jaakkola, Jouni Jk; Ikäheimo, Tiina M

    2014-03-28

    Both temperature and humidity may independently or jointly contribute to the risk of influenza infections. We examined the relations between the level and decrease of temperature, humidity and the risk of influenza A and B virus infections in a subarctic climate. We conducted a case-crossover study among military conscripts (n = 892) seeking medical attention due to respiratory symptoms during their military training period and identified 66 influenza A and B cases by PCR or serology. Meteorological data such as measures of average and decline in ambient temperature and absolute humidity (AH) during the three preceding days of the onset (hazard period) and two reference periods, prior and after the onset were obtained. The average temperature preceding the influenza onset was -6.8 ± 5.6°C and AH 3.1 ± 1.3 g/m3. A decrease in both temperature and AH during the hazard period increased the occurrence of influenza so that a 1°C decrease in temperature and 0.5 g decrease per m3 in AH increased the estimated risk by 11% [OR 1.11 (1.03 to 1.20)] and 58% [OR 1.58 (1.28 to 1.96)], respectively. The occurrence of influenza infections was positively associated with both the average temperature [OR 1.10 per 1°C (95% confidence interval 1.02 to 1.19)] and AH [OR 1.25 per g/m3 (1.05 to 1.49)] during the hazard period prior to onset. Our results demonstrate that a decrease rather than low temperature and humidity per se during the preceding three days increase the risk of influenza episodes in a cold climate.

  12. Decline in temperature and humidity increases the occurrence of influenza in cold climate

    PubMed Central

    2014-01-01

    Background Both temperature and humidity may independently or jointly contribute to the risk of influenza infections. We examined the relations between the level and decrease of temperature, humidity and the risk of influenza A and B virus infections in a subarctic climate. Methods We conducted a case-crossover study among military conscripts (n = 892) seeking medical attention due to respiratory symptoms during their military training period and identified 66 influenza A and B cases by PCR or serology. Meteorological data such as measures of average and decline in ambient temperature and absolute humidity (AH) during the three preceding days of the onset (hazard period) and two reference periods, prior and after the onset were obtained. Results The average temperature preceding the influenza onset was −6.8 ± 5.6°C and AH 3.1 ± 1.3 g/m3. A decrease in both temperature and AH during the hazard period increased the occurrence of influenza so that a 1°C decrease in temperature and 0.5 g decrease per m3 in AH increased the estimated risk by 11% [OR 1.11 (1.03 to 1.20)] and 58% [OR 1.58 (1.28 to 1.96)], respectively. The occurrence of influenza infections was positively associated with both the average temperature [OR 1.10 per 1°C (95% confidence interval 1.02 to 1.19)] and AH [OR 1.25 per g/m3 (1.05 to 1.49)] during the hazard period prior to onset. Conclusion Our results demonstrate that a decrease rather than low temperature and humidity per se during the preceding three days increase the risk of influenza episodes in a cold climate. PMID:24678699

  13. An analysis of the influence of the local effects of climatic and hydrological factors affecting new malaria cases in riverine areas along the Rio Negro and surrounding Puraquequara Lake, Amazonas, Brazil.

    PubMed

    Coutinho, Paulo Eduardo Guzzo; Candido, Luiz Antonio; Tadei, Wanderli Pedro; da Silva Junior, Urbano Lopes; Correa, Honorly Katia Mestre

    2018-04-26

    A study was conducted at three sampling regions along the Rio Negro and surrounding Puraquequara Lake, Amazonas, Brazil. The aim was to determine the influence of the local effects of climatic and hydrological variables on new malaria cases. Data was gathered on the river level, precipitation, air temperature, and the number of new cases of autochthonous malaria between January 2003 and December 2013. Monthly averages, time series decompositions, cross-correlations, and multiple regressions revealed different relationships at each location. The sampling region in the upper Rio Negro indicated no statistically significant results. However, monthly averages suggest that precipitation and air temperature correlate positively with the occurrence of new cases of malaria. In the mid Rio Negro and Puraquequara Lake, the river level positively correlated, and temperature negatively correlated with new transmissions, while precipitation correlated negatively in the mid Rio Negro and positively on the lake. Overall, the river level is a key variable affecting the formation of breeding sites, while precipitation may either develop or damage them. A negative temperature correlation is associated with the occurrence of new annual post-peak cases of malaria, when the monthly average exceeds 28.5 °C. This suggests that several factors contribute to the occurrence of new malaria cases as higher temperatures are reached at the same time as precipitation and the river levels are lowest. Differences between signals and correlation lags indicate that local characteristics have an impact on how different variables influence the disease vector's life cycle, pathogens, and consequently, new cases of malaria.

  14. A lower occurrence rate of bright X-ray flares in SN-GRBs than z < 1 GRBs: evidence of energy partitions?

    NASA Astrophysics Data System (ADS)

    Mu, Hui-Jun; Gu, Wei-Min; Mao, Jirong; Liu, Tong; Hou, Shu-Jin; Lin, Da-Bin; Wang, Junfeng; Fang, Taotao; Liang, En-Wei

    2018-05-01

    The occurrence rates of bright X-ray flares in z < 1 gamma-ray bursts (GRBs) with or without observed supernovae (SNe) association were compared. Our Sample I: the z < 1 long GRBs (LGRBs) with SNe association (SN-GRBs) and with early Swift/X-Ray Telescope (XRT) observations, consists of 18 GRBs, among which only two GRBs have bright X-ray flares. Our Sample II: for comparison, all the z < 1 LGRBs without observed SNe association and with early Swift/XRT observations, consists of 45 GRBs, among which 16 GRBs present bright X-ray flares. Thus, the study indicates a lower occurrence rate of bright X-ray flares in Sample I (11.1%) than in Sample II (35.6%). In addition, if dim X-ray fluctuations are included as flares, then 16.7% of Sample I and 55.6% of Sample II are found to have flares, again showing the discrepancy between these two samples. We examined the physical origin of these bright X-ray flares and found that most of them are probably related to the central engine reactivity. To understand the discrepancy, we propose that such a lower occurrence rate of flares in the SN-GRB sample may hint at an energy partition among the GRB, SNe, and X-ray flares under a saturated energy budget of massive star explosion.

  15. Reliability and comparison of gain values with occurrence of saccades in the EyeSeeCam video head impulse test (vHIT).

    PubMed

    Korsager, Leise Elisabeth Hviid; Schmidt, Jesper Hvass; Faber, Christian; Wanscher, Jens Højberg

    2016-12-01

    The vHIT (video head impulse test) investigates the vestibular function in two ways: a VOR (vestibulo-ocular reflex) gain value and a head impulse diagram. From the diagram covert and overt saccades can be detected. Evaluation of the vestibular function based on vHIT depends on both parameters. There is a lack of knowledge regarding the reliability of the two parameters. The objective was to investigate the reliability of vHIT by comparing gain values between examiners on the same subjects, and to see how differences affected the occurrence of saccades. 25 subjects who had undergone cochlear implant (CI) surgery. Subjects were tested using the vHIT by two of four different examiners. Two judges interpreted the occurrence of saccades in the diagram. VOR gain values and the occurrence of saccades in the diagram. Differences in gain values between examiners varied from 0.2 to 0.58 with an average of 0.14 (95 % CI 0.12-0.16) on the right ear and 0.17 (95 % CI 0.15-0.19) on the left ear. Occurrences of saccades in the same patient were reproduced in 93 % of the cases by all examiners. Kappa's coefficient on the occurrence of saccades was 0.83. Interclass correlation coefficient (ICC) of the gain values between examiners ranged from 0.62 to 0.70. Differences in gain values amongst examiners did not seem to affect the occurrence of saccades in the same patient. The occurrence of saccades, therefore, seems to be more reliable than the gain value in the evaluation of the vestibular function. Interpretation of vHIT results should, therefore, first depend on the occurrence of saccades and second on the gain value.

  16. [PULMONARY COMPLICATIONS IN CHILDREN, OPERATED ON FOR INBORN HEART FAILURES IN THE ARTIFICIAL BLOOD CIRCULATION ENVIRONMENT].

    PubMed

    Moshkivska, L V; Nastenko, E A; Golovenko, O S; Lazoryshynets, V V

    2015-11-01

    The risk factors of pulmonary complications occurrence were analyzed in children, operated on for inborn heart failures in atrificial blood circulation environment. Pulmonary complications rate and the risk factors of their occurrence were analyzed.

  17. Estimating effects of improved drinking water and sanitation on cholera.

    PubMed

    Leidner, Andrew J; Adusumilli, Naveen C

    2013-12-01

    Demand for adequate provision of drinking-water and sanitation facilities to promote public health and economic growth is increasing in the rapidly urbanizing countries of the developing world. With a panel of data on Asia and Africa from 1990 to 2008, associations are estimated between the occurrence of cholera outbreaks, the case rates in given outbreaks, the mortality rates associated with cholera and two disease control mechanisms, drinking-water and sanitation services. A statistically significant and negative effect is found between drinking-water services and both cholera case rates as well as cholera-related mortality rates. A relatively weak statistical relationship is found between the occurrence of cholera outbreaks and sanitation services.

  18. Aerobic Exercise during Pregnancy and Presence of Fetal-Maternal Heart Rate Synchronization

    PubMed Central

    Van Leeuwen, Peter; Gustafson, Kathleen M.; Cysarz, Dirk; Geue, Daniel; May, Linda E.; Grönemeyer, Dietrich

    2014-01-01

    It has been shown that short-term direct interaction between maternal and fetal heart rates may take place and that this interaction is affected by the rate of maternal respiration. The aim of this study was to determine the effect of maternal aerobic exercise during pregnancy on the occurrence of fetal-maternal heart rate synchronization. Methods In 40 pregnant women at the 36th week of gestation, 21 of whom exercised regularly, we acquired 18 min. RR interval time series obtained simultaneously in the mothers and their fetuses from magnetocardiographic recordings. The time series of the two groups were examined with respect to their heart rate variability, the maternal respiratory rate and the presence of synchronization epochs as determined on the basis of synchrograms. Surrogate data were used to assess whether the occurrence of synchronization was due to chance. Results In the original data, we found synchronization occurred less often in pregnancies in which the mothers had exercised regularly. These subjects also displayed higher combined fetal-maternal heart rate variability and lower maternal respiratory rates. Analysis of the surrogate data showed shorter epochs of synchronization and a lack of the phase coordination found between maternal and fetal beat timing in the original data. Conclusion The results suggest that fetal-maternal heart rate coupling is present but generally weak. Maternal exercise has a damping effect on its occurrence, most likely due to an increase in beat-to-beat differences, higher vagal tone and slower breathing rates. PMID:25162592

  19. Aerobic exercise during pregnancy and presence of fetal-maternal heart rate synchronization.

    PubMed

    Van Leeuwen, Peter; Gustafson, Kathleen M; Cysarz, Dirk; Geue, Daniel; May, Linda E; Grönemeyer, Dietrich

    2014-01-01

    It has been shown that short-term direct interaction between maternal and fetal heart rates may take place and that this interaction is affected by the rate of maternal respiration. The aim of this study was to determine the effect of maternal aerobic exercise during pregnancy on the occurrence of fetal-maternal heart rate synchronization. In 40 pregnant women at the 36th week of gestation, 21 of whom exercised regularly, we acquired 18 min. RR interval time series obtained simultaneously in the mothers and their fetuses from magnetocardiographic recordings. The time series of the two groups were examined with respect to their heart rate variability, the maternal respiratory rate and the presence of synchronization epochs as determined on the basis of synchrograms. Surrogate data were used to assess whether the occurrence of synchronization was due to chance. In the original data, we found synchronization occurred less often in pregnancies in which the mothers had exercised regularly. These subjects also displayed higher combined fetal-maternal heart rate variability and lower maternal respiratory rates. Analysis of the surrogate data showed shorter epochs of synchronization and a lack of the phase coordination found between maternal and fetal beat timing in the original data. The results suggest that fetal-maternal heart rate coupling is present but generally weak. Maternal exercise has a damping effect on its occurrence, most likely due to an increase in beat-to-beat differences, higher vagal tone and slower breathing rates.

  20. Incidence of mesothelioma in Lombardy, Italy: exposure to asbestos, time patterns and future projections.

    PubMed

    Mensi, Carolina; De Matteis, Sara; Dallari, Barbara; Riboldi, Luciano; Bertazzi, Pier Alberto; Consonni, Dario

    2016-09-01

    In Italy, asbestos has been extensively used from 1945 to 1992. We evaluated the impact of exposure to asbestos on occurrence of malignant mesothelioma (MM) in the Lombardy Region, Northwest Italy, the most populated and industrialised Italian region. From the Lombardy Mesothelioma Registry, we selected all incident cases of MM diagnosed between 2000 and 2012. We described sources of exposure to asbestos and examined time trends of MM rates. Using Poisson age-cohort models, we derived projections of burden of MM in the Lombardy population for the period 2013-2029. In 2000-2012, we recorded 4442 cases of MM (2850 men, 1592 women). Occupational exposure to asbestos was more frequent in men (73.6%) than in women (38.2%). Non-occupational exposure was found for 13.6% of women and 3.6% of men. The average number of cases of MM per year was still increasing (+3.6% in men, +3.3% in women). Incidence rates were still increasing in individuals aged 65+ years and declining in younger people. A maximum of 417 cases of MM (267 men, 150 women) are expected in 2019. We forecast there will be 6832 more cases (4397 in men, 2435 in women) in the period 2013-2029, for a total of 11 274 cases of MM (7247 in men, 4027 in women) in 30 years. This study documented a high burden of MM in both genders in the Lombardy Region, reflecting extensive occupational (mainly in men) and non-occupational (mainly in women) exposure to asbestos in the past. Incidence rates are still increasing; a downturn in occurrence of MM is expected to occur after 2019. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. [Correlation of insulin-like growth factor-1 (IGF-1) to angiogenesis of breast cancer in IGF-1-deficient mice].

    PubMed

    Tang, Hong-Bo; Ren, Yu-Ping; Zhang, Jun; Ma, Shi-Hui; Gao, Feng; Wu, Yi-Ping

    2007-11-01

    Insulin-like growth factors (IGFs) play important roles in the development and progression of tumors. But the mechanism of tumorigenesis in relation to IGF-1 is unclear yet. This study was to explore the correlation of circulating IGF-1 level to the angiogenesis of breast cancer in IGF-1-deficient mice. The liver-specific IGF-1-deficient (LID) mice and control mice were injected with 7,12-dimethybenz(a)anthracene (DMBA) to develop breast cancer. Ginsenoside Rg3 was used to intervene tumor growth. The occurrence rates of breast cancer were compared. The expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) was detected by immunohistochemistry. The occurrence rate of breast cancer was 66.67% in untreated control mice, 33.33% in untreated LID mice, 36.00% in Rg3-treated control mice, and 12.00% in Rg3-treated LID mice. The tumor size was (0.79+/-0.20) cm in untreated control mice, (0.37+/-0.08) cm in untreated LID mice, (0.32+/-0.08) cm in Rg3-treated control mice, and (0.15+/-0.05) cm in Rg3-treated LID mice. The average light density and positive rate of VEGF were the highest in untreated control mice (0.34+/-0.10 and 0.04+/-0.02, P<0.05), and the lowest in Rg3-treated LID mice (0.13+/-0.03 and 0.01+/-0.00, P<0.05). The MVD was 31.9+/-5.3 in untreated control mice, 26.8+/-4.9 in untreated LID mice, 20.1+/-4.9 in Rg3-treated control mice, and 14.4+/-4.9 in Rg3-treated LID mice. Circulating IGF-1 plays a role in the onset and development of breast cancer. Degrading serum IGF-1 level could inhibit angiogenesis and growth of breast cancer. Rg3 could promote this effect.

  2. Prevalence and Risk Factors for Early Seizure in Patients with Traumatic Brain Injury: Analysis from National Trauma Data Bank.

    PubMed

    Majidi, Shahram; Makke, Yamane; Ewida, Amr; Sianati, Bahareh; Qureshi, Adnan I; Koubeissi, Mohamad Z

    2017-08-01

    Traumatic brain injury (TBI) is a well-known risk factor for seizures. We aimed to identify the frequency and risk factors for seizure occurrence during hospitalization for TBI. We used ICD-9-CM codes to identify patients 18 years of age or older from the National Trauma Data Bank who were admitted with TBI. We also used ICD-9-CM codes to identify the subset who had seizures during hospitalization. Patient demographics, comorbidities, Glasgow Coma Scale (GCS) score, Injury Severity Score Abbreviated Injury Scale (ISSAIS), in-hospital complications, and discharge disposition were compared in the seizure group (SG) and no-seizure group (NSG). A total of 1559 patients had in-hospital seizures, comprising 0.4% of all patients admitted with TBI. The mean age of SG was 3 years older than NSG [51 vs. 48; p < 0.0001]. African-American ethnicity (20 vs. 12%, p < 0.0001) and moderate TBI (8 vs. 4%, p < 0.0001) were more common in SG. History of alcohol dependence was more common in the SG (25 vs. 11%, p < 0.0001). Fall was the most common mechanism of injury in SG (56 vs. 36% in NSG; p < 0.0001). Subdural hematoma was more common in SG (31 vs. 21%, p < 0.0001). SG had higher rates of pneumonia, ARDS, acute kidney injury, and increased ICP. The average length of hospital stay was significantly higher in SG (10 vs. 6 days, p < 0.0001), and these patients had higher rate of discharge to nursing facility (32 vs. 25%, p < 0.0001). In-hospital seizures occur in 0.4% of all TBI patients. Although infrequent, seizure occurrence is associated with higher rates of hospital complications such as pneumonia and ARDS and is an independent predictor of longer hospital stay and worse hospital outcome.

  3. Tobacco imagery in Bollywood films: 2006–2008

    PubMed Central

    Nazar, Gaurang P; Gupta, Vinay K; Millett, Christopher; Arora, Monika

    2013-01-01

    Objective To estimate exposure to tobacco imagery in youth-rated Bollywood films, and examine the results in light of recent developments in India's film rating system. Methods Content coding of 44 top grossing Bollywood films (including 38 youth-rated films) released during 2006–2008 was undertaken to estimate tobacco occurrences and impressions. Results Out of the 38 youth-rated (U and U/A) films coded, 50% contained tobacco imagery. Mean tobacco occurrences were 1.9, 2.9 and 13.7 per U, U/A and adult (A) rated films, respectively. Top grossing youth-rated films delivered 1.91 billion tobacco impressions to Indian cinema audiences. Conclusions Half the youth-rated Bollywood films contain tobacco imagery resulting in large population level exposure in India, relative to other countries. Measures to reduce youth exposure to tobacco imagery through films, such as restricting access through the rating system, will complement other tobacco control measures. PMID:27326073

  4. The co-occurrence of aggression and self-harm: systematic literature review.

    PubMed

    O'Donnell, Orla; House, Allan; Waterman, Mitch

    2015-04-01

    Epidemiological research supports an association between aggression and self-harm through data on the frequency with which individuals exhibit both behaviours. Unbiased evidence, however, is needed to draw conclusions about the nature and extent of co-occurrence. Systematic review of published studies was undertaken to evaluate whether or not the frequency with which aggression and self-harm co-occur is beyond that which would be expected by chance. Outcome measures included: (a) between-group differences on a standardised aggression/self-harm measure - the groups defined by scores on a measure of the other behaviour; (b) correlations between the two behaviours; (c) co-occurrence rates in populations defined by the presence of either behaviour; (d) co-occurrence rates in populations not defined by either behaviour. Odds ratios were calculated for studies presenting complete frequency data. 123 studies, some yielding more than one type of result, met the inclusion criteria. Most case-control studies found elevated levels of aggression in self-harming populations (or self-harm in aggressive populations) compared to controls. The majority of correlational, co-occurrence rate, and odds ratio data found aggression and self-harm to be associated. Results were subject to descriptive synthesis only and thus, unable to report an overall effect size. Evidence suggests that aggression and self-harm frequently co-occur. Such evidence necessitates more theoretical discussion and associated research on the source and nature of co-occurrence. Nonetheless, individuals who present with one behaviour may be considered an 'at-risk' group in terms of exhibiting the other. Such evidence holds implications for practice (e.g. risk assessment). Copyright © 2015. Published by Elsevier B.V.

  5. A character network study of two Sci-Fi TV series

    NASA Astrophysics Data System (ADS)

    Tan, M. S. A.; Ujum, E. A.; Ratnavelu, K.

    2014-03-01

    This work is an analysis of the character networks in two science fiction television series: Stargate and Star Trek. These networks are constructed on the basis of scene co-occurrence between characters to indicate the presence of a connection. Global network structure measures such as the average path length, graph density, network diameter, average degree, median degree, maximum degree, and average clustering coefficient are computed as well as individual node centrality scores. The two fictional networks constructed are found to be quite similar in structure which is astonishing given that Stargate only ran for 18 years in comparison to the 48 years for Star Trek.

  6. The Rise of Flowering Plants and Land Surface Physics: The Cretaceous and Eocene Were Different

    NASA Astrophysics Data System (ADS)

    Upchurch, G. R.; Feild, T.

    2010-12-01

    The Cretaceous and Eocene have served as the poster children of past greenhouse climates. One difference between the two time periods is that angiosperms (flowering plants) underwent a major diversification and rise to dominance during the mid-Cretaceous to Paleocene. Flowering plants differ from all other living and fossil plants in having significantly higher rates of transpiration and photosynthesis, which in modern leaves correlate with the density of venation (Dv), a feature that can be measured directly from fossils. This increase in Dv, coupled with an increase in the abundance of angiosperms, is thought to have had major impact on the climate system. This is, in part, because transpiration plays an important role in determining the ratio of sensible to latent heat flux from the land surface and in determining precipitation rate in regions such as the equatorial rainforest. Analysis of Dv in fossil leaves indicates two phases of increase in transpiration rate for angiosperms during the Cretaceous-Paleocene. The oldest known angiosperms (Aptian-early Albian) have a low Dv characteristic of extant and fossil ferns and gymnosperms. At this time angiosperms are low-stature plants of minor importance in terms of relative abundance and diversity (<5%). The first phase of Dv increase occurs during the Late Albian to Cenomanian, where average Dv is 40% greater than that of conifers and ferns, and maximum Dv reaches levels characteristic of many trees from the temperate zone. This first phase coincides with the first local dominance of angiosperms, the first occurrence of moderate to large angiosperm trees (up to 1 m in diameter) , and the first common occurrence of angiosperms in the Arctic. The second phase of Dv increase occurs during the Maastrichtian to Paleocene, where average Dv reaches levels characteristic of modern tropical forests and maximum Dv reaches the level found in highly productive modern vegetation. This second phase coincides with the rise to dominance of angiosperms in regional vegetation, a corresponding decline of conifers and ferns, and the modernization of hydraulic architecture in angiosperm wood. The full implications of these changes in land cover have yet to be explored with Earth System models, especially outside the tropics. However, under similar LAI and pCO2, Cretaceous vegetation would have made a greater contribution to global warming than Eocene vegetation through greater sensible heating of the land surface and possibly reduced liquid clouds due to decreased transpiration.

  7. Ambient Air Pollution and Apnea and Bradycardia in High-Risk Infants on Home Monitors

    PubMed Central

    Klein, Mitchel; Flanders, W. Dana; Mulholland, James A.; Freed, Gary; Tolbert, Paige E.

    2011-01-01

    Background: Evidence suggests that increased ambient air pollution concentrations are associated with health effects, although relatively few studies have specifically examined infants. Objective: We examined associations of daily ambient air pollution concentrations with central apnea (prolonged pauses in breathing) and bradycardia (low heart rate) events among infants prescribed home cardiorespiratory monitors. Methods: The home monitors record the electrocardiogram, heart rate, and respiratory effort for detected apnea and bradycardia events in high-risk infants [primarily premature and low birth weight (LBW) infants]. From August 1998 through December 2002, 4,277 infants had 8,960 apnea event-days and 29,450 bradycardia event-days in > 179,000 days of follow-up. We assessed the occurrence of apnea and bradycardia events in relation to speciated particulate matter and gaseous air pollution levels using a 2-day average of air pollution (same day and previous day), adjusting for temporal trends, temperature, and infant age. Results: We observed associations between bradycardia and 8-hr maximum ozone [odds ratio (OR) = 1.049 per 25-ppb increase; 95% confidence interval (CI), 1.021–1.078] and 1-hr maximum nitrogen dioxide (OR =1.025 per 20-ppb increase; 95% CI, 1.000–1.050). The association with ozone was robust to different methods of control for time trend and specified correlation structure. In secondary analyses, associations of apnea and bradycardia with pollution were generally stronger in infants who were full term and of normal birth weight than in infants who were both premature and LBW. Conclusions: These results suggest that higher air pollution concentrations may increase the occurrence of apnea and bradycardia in high-risk infants. PMID:21447453

  8. Long-term effects of good handling practices during the pre-weaning period of crossbred dairy heifer calves.

    PubMed

    Silva, Luciana Pontes; Sant'Anna, Aline Cristina; Silva, Lívia Carolina Magalhães; Paranhos da Costa, Mateus José Rodrigues

    2017-01-01

    The aim of this study was to determine whether applying good practices of handling during the pre-weaning period have long-term effects on behavioral and physiological indicators, health status, and average daily gain (ADG) of crossbred Bos taurus × Bos indicus heifer calves. During the pre-weaning period, 98 crossbred of Holstein × Gir heifer calves were allotted into three treatments: (1) good practices of handling + brushing (GPB; n = 25), (2) good practices of handling (GP; n = 25), and (3) control (n = 48). Every 2 months, four evaluation periods (EV 1 to EV 4 ) were conducted to record data. Behavioral indicators comprised time to drive (TD), flight speed (FS), flight distance (FD), and composite reactivity score (CRS). Physiological indicators of acute stress during handling comprised respiratory and heart rates. Health status comprised data regarding occurrence of most common diseases (i.e., pneumonia and anaplasmosis). Collected data were analyzed by using a linear mixed model for repeated measures, Tukey's test, and chi-squared procedures. Treatment influenced (P < 0.05) TD, FS, and FD but not CRS (P = 0.78). From EV 1 to EV 3 , the control calves had the lowest TD. The GPB group had lower FS than the control but did not differ from GP. The GPB group had lower FD means than the other two groups in EV 2 , EV 3 , and EV 4 . No differences (P > 0.05) due to treatment were observed on heart and respiratory rates, ADG, or occurrence of pneumonia and anaplasmosis. It was concluded that adoption of good practices of handling during pre-weaning period may lead to long-term positive effects.

  9. Yasuní--a hotspot for jaguars Panthera onca (Carnivora: Felidae)? Camera-traps and jaguar activity at Tiputini Biodiversity Station, Ecuador.

    PubMed

    Blake, John G; Mosquera, Diego; Guerra, Jaime; Loiselle, Bette A; Romo, David; Swing, John Kelly

    2014-06-01

    Jaguars (Panthera onca) are the largest predator in lowland forests of Amazonia but there have been few studies on their occurrence and activity in such forests. Here, we used camera traps to document the occurrence and activity of jaguars within a local area (-650ha) of lowland forest of Eastern Ecuador, over two sample periods (2005-2008, 7 222 trap days; 2010-2012, 6 199 trap days). We accumulated 151 independent photos of jaguars (189 total photographs) that represented 21 different individuals, including 11 males (114 photographs), seven females (32 photographs), and three that could not be assigned to a sex. Individual jaguars varied in the number of months they were recorded in the area; ten were photographed in only one month; five were photographed over periods of 8 to 22 months; and five from 45 to 81 months. Capture rates across all camera stations averaged 10.6/1 000 trap days; capture rates did not differ between the two sample periods. Male jaguars were more active during the day (06:00am-18:00pm; 71% of photographs), whereas females were equally active during the day and night. Monthly activity was variable but showed no consistent pattern. Although the study area is much smaller than typical home ranges of jaguars, the area is clearly visited by a large number of different individuals, some of whom repeatedly visit the area, indicating that it forms part of their home range. Other individuals likely were simply passing through the area. Based on the number of jaguars recorded during this study, it is clear that the region is an important area for conservation. Continued protection will be needed to ensure that populations ofjaguars and other species remain viable.

  10. Effect of osteopathic manipulative treatment on gastrointestinal function and length of stay of preterm infants: an exploratory study

    PubMed Central

    2011-01-01

    Background Organizational improvement of neonatal intensive care units requires strict monitoring of preterm infants, including routine assessment of physiological functions of the gastrointestinal system and optimized procedures for the definition of appropriate discharge timing. Methods We conducted a prospective study on the effect of osteopathic manipulative treatment in a cohort of N = 350 consecutive premature infants admitted to a neonatal intensive care unit without any major complication between 2005 and 2008. In addition to ordinary care, N = 162 subjects received osteopathic treatment. Endpoints of the study were differences between study and control groups in terms of excessive length of stay and gastrointestinal symptoms, defined as the upper quartiles in the distribution of the overall population. Statistical analysis was based on crude and adjusted odds ratios from multivariate logistic regression. Results Baseline characteristics were evenly distributed across treated/control groups, except for the rate of infants unable to be oral fed at admission, significantly higher among those undergoing osteopathic care (p = .03). Osteopathic treatment was significantly associated with a reduced risk of an average daily occurrence of gut symptoms per subject above .44 (OR = 0.45; 0.26-0.74). Gestational age lower or equal to 32 weeks, birth weight lower or equal to 1700 grams and no milk consumption at admission were associated with higher rates of length of stay in the unit of at least 28 days, while osteopathic treatment significantly reduced such risk (OR = 0.22;0.09-0.51). Conclusions In a population of premature infants, osteopathic manipulative treatment showed to reduce a high occurrence of gastrointestinal symptoms and an excessive length of stay in the NICU. Randomized control studies are needed to generalize these results to a broad population of high risk newborns. PMID:21711535

  11. Midlatitude detection of ELF whistlers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sentman, D.D.; Ehring, D.A.

    1994-02-01

    Narrow-band, whistlerlike magnetic events distinguished by nearly monochromatic signals decreasing in frequency with time have been observed for the first time at midlatitudes in the ELF band. Measurements performed during September 3 to October 5, 1985 at Table Mountain, California (34.4{degrees}N, 117.7{degrees}W), show that the frequency and dispersion characteristics of these events are similar to events detected at auroral latitudes, including a narrow-band magnetic signal monotonically decreasing in frequency from 120 to 60 Hz over a 40 s interval with a mean center frequency of approximately 90 Hz. No echoes were observed. Maximum amplitudes of the magnetic signals ranged frommore » just above the approximately 1 pT Hz{sup {minus}1/2} floor of the ambient background to roughly 20 pT Hz{sup {minus}1/2}. The polarization was predominantly linear in the geographic east-west direction. The midlatitude ELF whistlers reported here have a significantly lower average daily rate of occurrence than those reported for auroral latitudes. However, as with the high-latitude events, they displayed an occurrence rate that is maximum during local daytime. Following Heacock, it is suggested that a possible source for these events is whistler mode lion roars occurring in field-aligned ducts of enhanced cold plasma densities in the magnetosheath into the polar cusp, the waves may propagate to the Earth through the cusp acting as a waveguide. Although lightning is usually considered to be the dominant source of ELF noise in the Earth ionosphere cavity, magnetosheath ELF noise coupled into the cavity at high latitudes may represent an additional source. The fractional intensities of the natural ELF noise power within the cavity that are generated by this mechanism are presently unknown. 28 refs., 5 figs., 1 tab.« less

  12. A survey for rhinitis in an automotive ring manufacturing plant.

    PubMed

    Park, Dong-Uk; Jin, Ku-Won; Koh, Dong-Hee; Kim, Byung-Kyu; Kim, Kyu-Sang; Park, Doo-Yong

    2008-08-01

    We report findings regarding otolaryngologist-confirmed rhinitis, current exposure to MWF aerosols, fungi, and endotoxins for workers in a plant manufacturing automobile piston rings. Questionnaire data showed that 61.5% of 187 workers exhibited rhinitis-related symptoms. Rhinitis was confirmed in 99 of 115 workers whom were medically examined. Otolaryngologist-confirmed rhinitis was present in 10 of 19 grinding workers (52.6%), 67 of 142 production workers (47.2%), and 22 of 26 quality control (QC) workers (84.6%). These rates are much higher than the rates of rhinitis-related symptoms in automobile plants and other occupational settings and quite high even allowing for the common occurrence of rhinitis in the general population. We found that rhinitis could develop even in workers exposed to less than 0.5mg/m(3) MWF aerosol. The average exposure to fungi exceeded 10 x 10(3) CFU/m(3), a level higher than that reported for other automobile plants. Although we were unable to identify significant risk factors for rhinitis using only the physician-confirmed rhinitis cases, this study concludes that exposure to MWF aerosol, which would include microbes and metals, could contribute to a high occurrence of rhinitis in grinding and production workers. Forty-nine workers (63.6%) of 77 rhinitis patients in grinding and production operations were determined to handle synthetic MWF directly. For QC workers, for whom the prevalence of physician-confirmed rhinitis was highest, exposure to a low level of MWF aerosol, including specific microbe species we couldn't identify, bright light, dry air, and certain work characteristics during inspection are possible risk factors for development of rhinitis. Further studies including identification of fungi species should be conducted so a firm conclusion can be made regarding the development of rhinitis in QC manufacturing plant workers.

  13. OCCURRENCE OF A NEW GENERATION OF DISINFECTION BY-PRODUCTS

    EPA Science Inventory

    A survey of disinfection by-product (DBP) occurrence in the United States was conducted at 12 drinking water treatment plants. In addition to currently regulated DBPs, more than 50 DBPs that rated a high priority for potential toxicity were studied. These priority DBPs included...

  14. Subjective response of people to simulated sonic booms in their homes

    NASA Technical Reports Server (NTRS)

    McCurdy, David A.; Brown, Sherilyn A.; Hilliard, R. David

    2004-01-01

    In order to determine the effect of the number of sonic boom occurrences on annoyance, a computer-based system was developed for studying the subjective response of people to the occurrence of simulated sonic booms in their homes. The system provided a degree of control over the noise exposure not found in community surveys and a degree of situational realism not available in the laboratory. A system was deployed for eight weeks in each of 33 homes. Each day from 4 to 63 sonic booms were played as the test subject went about his or her normal activities. At the end of the day, the test subjects rated their annoyance to the sonic booms heard during the day. The sonic booms consisted of different combinations of waveforms, levels, and occurrence rates. The experiment confirmed that the increase in annoyance resulting from multiple occurrences can be modeled by the addition of the term "10 * log(number of occurrences)" to the sonic boom level. Of several noise metrics considered, perceived level was the best annoyance predictor. Comparisons of the subjective responses to the different sonic boom waveforms found no differences that were not accounted for by the noise metrics.

  15. Detecting Anthropogenic Disturbance on Weathering and Erosion Processes

    NASA Astrophysics Data System (ADS)

    Vanacker, V.; Schoonejans, J.; Bellin, N.; Ameijeiras-Mariño, Y.; Opfergelt, S.; Christl, M.

    2014-12-01

    Anthropogenic disturbance of natural vegetation can profoundly alter the physical, chemical and biological processes within soils. Rapid removal of topsoil during intense farming can result in an imbalance between soil production through chemical weathering and physical erosion, with direct implications on local biogeochemical cycling. However, the feedback mechanisms between soil erosion, chemical weathering and biogeochemical cycling in response to anthropogenic forcing are not yet fully understood. In this paper, we analyze dynamic soil properties for a rapidly changing anthropogenic landscape in the Spanish Betic Cordillera; and focus on the coupling between physical erosion, soil production and soil chemical weathering. Modern erosion rates were quantified through analysis of sediment deposition volumes behind check dams, and represent catchment-average erosion rates over the last 10 to 50 years. Soil production rates are derived from in-situ produced 10Be nuclide concentrations, and represent long-term flux rates. In each catchment, soil chemical weathering intensities were calculated for two soil-regolith profiles. Although Southeast Spain is commonly reported as the European region that is most affected by land degradation, modern erosion rates are low (140 t ha-1 yr-1). About 50 % of the catchments are losing soils at a rate of less than 60 t km-2 yr-1. Our data show that modern erosion rates are roughly of the same magnitude as the long-term or cosmogenically-derived erosion rates in the Betic Cordillera. Soils developed on weathered metamorphic rocks have no well-developed profile characteristics, and are generally thin and stony. Nevertheless, soil chemical weathering intensities are high; and question the occurrence of past soil truncation.

  16. Occurrence of 210Po in marine macroalgae inhabiting a coastal nuclear zone, southeast coast of India.

    PubMed

    Praveen Pole, R P; Feroz Khan, M; Godwin Wesley, S

    2017-04-01

    The activity concentration of 210 Po in 26 species of marine macroalgae found along coast near to a nuclear installation in southeast coast of India was studied. Phaeophytes were found to accumulate the maximum 210 Po concentration and chlorophytes the minimum. The average 210 Po activity concentration values in the three groups were 6.2 ± 2.5 Bq kg -1 (Chlorophyta), 14.4 ± 5.2 Bq kg -1 (Phaeophyta) and 11.3 ± 3.9 Bq kg -1 (Rhodophyta). A statistically significant variation in accumulation was found between groups (p < 0.05). The un-weighted dose rate to these algae due to 210 Po was calculated to be well below the benchmark dose limit of 10 μGy h -1 . Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Spatiotemporal Co-occurrence of Flanders and West Nile Viruses Within Culex Populations in Shelby County, Tennessee.

    PubMed

    Lucero, D E; Carlson, T C; Delisle, J; Poindexter, S; Jones, T F; Moncayo, A C

    2016-05-01

    West Nile virus (WNV) and Flanders virus (FLAV) can cocirculate in Culex mosquitoes in parts of North America. A large dataset of mosquito pools tested for WNV and FLAV was queried to understand the spatiotemporal relationship between these two viruses in Shelby County, TN. We found strong evidence of global clustering (i.e., spatial autocorrelation) and overlapping of local clustering (i.e., Hot Spots based on Getis Ord Gi*) of maximum likelihood estimates (MLE) of infection rates (IR) during 2008-2013. Temporally, FLAV emerges and peaks on average 10.2 wk prior to WNV based on IR. Higher levels of WNV IR were detected within 3,000 m of FLAV-positive pool buffers than outside these buffers. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Burden and trends of type-specific human papillomavirus infections and related diseases in the latin america and Caribbean region.

    PubMed

    Parkin, D Maxwell; Almonte, Maribel; Bruni, Laia; Clifford, Gary; Curado, Maria-Paula; Piñeros, Marion

    2008-08-19

    We present the burden of human papillomavirus (HPV)-related cancers (cancers of the cervix, anogenital region, oral cavity and pharynx) in terms of incidence and mortality, for the countries of the Latin America and Caribbean region. The region is a high-risk area for cancer of the cervix and, although incidence has declined since the 1960s, projected demographic changes imply that the actual burden of new cases will increase by more than 75% in the next 20 years, while the average and at diagnosis will increase. Approximately 65% of cervical cancer cases and 50% of the high risk lesions are associated with HPV-16 and 18. Incidence rates of other HPV-related cancers are significantly lower. The paper also describes the estimated impact of genital warts and the limited data available on the occurrence of HPV infections of the upper aerodigestive tract in the region.

  19. Methods for Estimating Magnitude and Frequency of Floods in Rural Basins in the Southeastern United States: South Carolina

    USGS Publications Warehouse

    Feaster, Toby D.; Gotvald, Anthony J.; Weaver, J. Curtis

    2009-01-01

    For more than 50 years, the U.S. Geological Survey (USGS) has been developing regional regression equations that can be used to estimate flood magnitude and frequency at ungaged sites. Flood magnitude relates to the volume of flow that occurs over some period of time and usually is presented in cubic feet per second. Flood frequency relates to the probability of occurrence of a flood; that is, on average, what is the likelihood that a flood with a specified magnitude will occur in any given year (1 percent chance, 10 percent chance, 50 percent chance, and so on). Such flood estimates are needed for the efficient design of bridges, highway embankments, levees, and other structures near streams. In addition, these estimates are needed for the effective planning and management of land and water resources, to protect lives and property in flood-prone areas, and to determine flood-insurance rates.

  20. Exploration and Trapping of Mortal Random Walkers

    NASA Astrophysics Data System (ADS)

    Yuste, S. B.; Abad, E.; Lindenberg, Katja

    2013-05-01

    Exploration and trapping properties of random walkers that may evanesce at any time as they walk have seen very little treatment in the literature, and yet a finite lifetime is a frequent occurrence, and its effects on a number of random walk properties may be profound. For instance, whereas the average number of distinct sites visited by an immortal walker grows with time without bound, that of a mortal walker may, depending on dimensionality and rate of evanescence, remain finite or keep growing with the passage of time. This number can in turn be used to calculate other classic quantities such as the survival probability of a target surrounded by diffusing traps. If the traps are immortal, the survival probability will vanish with increasing time. However, if the traps are evanescent, the target may be spared a certain death. We analytically calculate a number of basic and broadly used quantities for evanescent random walkers.

  1. Iatrogenic bile duct strictures: a review of 22 cases.

    PubMed

    Ersumo, Tessema

    2003-10-01

    The incidence of iatrogenic bile duct strictures in Ethiopia appears to be increasing. Of 27 patients that sustained bile duct injuries at open cholecystectomy, admitted during May 1996 to December 2002, 22 cases of bile duct strictures are presented to evaluate outcome of treatment. The mean age was 40 years, 15 females. Twenty-one were referrals. The usual presenting features were biliary peritonitis and jaundice. The average time lapse between the original surgery and admission to hospital was eight months. About 73% had Bismuth grade III-IV strictures and all patients underwent Roux-en-Y hepatico-jejunostomy. Postoperatively, biliary-cutaneous fistula, recurrent ascending cholangitis and wound infection were observed frequently. The overall mortality rate was 13.6%. Bile duct injuries and strictures occur in young productive age groups. Prevention of the occurrence of bile duct injury and its progression to a devastating stricture reduces morbidity and mortality.

  2. The radiation protection problems of high altitude and space flight

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fry, R.J.M.

    1993-04-01

    This paper considers the radiation environment in aircraft at high altitudes and spacecraft in low earth orbit and in deep space and the factors that influence the dose equivalents. Altitude, latitude and solar cycle are the major influences for flights below the radiation belts. In deep space, solar cycle and the occurrence of solar particle events are the factors of influence. The major radiation effects of concern are cancer and infertility in males. In high altitude aircraft the radiation consists mainly of protons and neutrons, with neutrons contributing about half the equivalent dose. The average dose rate at altitudes ofmore » transcontinental flights that approach the polar regions are greater by a factor of about 2.5 than on routes at low latitudes. Current estimates of does to air crews suggest they are well within the ICRP (1990) recommended dose limits for radiation workers.« less

  3. Assuring Life in Composite Systems

    NASA Technical Reports Server (NTRS)

    Chamis, Christos c.

    2008-01-01

    A computational simulation method is presented to assure life in composite systems by using dynamic buckling of smart composite shells as an example. The combined use of composite mechanics, finite element computer codes, and probabilistic analysis enable the effective assessment of the dynamic buckling load of smart composite shells. A universal plot is generated to estimate the dynamic buckling load of composite shells at various load rates and probabilities. The shell structure is also evaluated with smart fibers embedded in the plies right below the outer plies. The results show that, on the average, the use of smart fibers improved the shell buckling resistance by about 9% at different probabilities and delayed the buckling occurrence time. The probabilistic sensitivities results indicate that uncertainties in the fiber volume ratio and ply thickness have major effects on the buckling load. The uncertainties in the electric field strength and smart material volume fraction have moderate effects and thereby in the assured life of the shell.

  4. Calibration of a texture-based model of a ground-water flow system, western San Joaquin Valley, California

    USGS Publications Warehouse

    Phillips, Steven P.; Belitz, Kenneth

    1991-01-01

    The occurrence of selenium in agricultural drain water from the western San Joaquin Valley, California, has focused concern on the semiconfined ground-water flow system, which is underlain by the Corcoran Clay Member of the Tulare Formation. A two-step procedure is used to calibrate a preliminary model of the system for the purpose of determining the steady-state hydraulic properties. Horizontal and vertical hydraulic conductivities are modeled as functions of the percentage of coarse sediment, hydraulic conductivities of coarse-textured (Kcoarse) and fine-textured (Kfine) end members, and averaging methods used to calculate equivalent hydraulic conductivities. The vertical conductivity of the Corcoran (Kcorc) is an additional parameter to be evaluated. In the first step of the calibration procedure, the model is run by systematically varying the following variables: (1) Kcoarse/Kfine, (2) Kcoarse/Kcorc, and (3) choice of averaging methods in the horizontal and vertical directions. Root mean square error and bias values calculated from the model results are functions of these variables. These measures of error provide a means for evaluating model sensitivity and for selecting values of Kcoarse, Kfine, and Kcorc for use in the second step of the calibration procedure. In the second step, recharge rates are evaluated as functions of Kcoarse, Kcorc, and a combination of averaging methods. The associated Kfine values are selected so that the root mean square error is minimized on the basis of the results from the first step. The results of the two-step procedure indicate that the spatial distribution of hydraulic conductivity that best produces the measured hydraulic head distribution is created through the use of arithmetic averaging in the horizontal direction and either geometric or harmonic averaging in the vertical direction. The equivalent hydraulic conductivities resulting from either combination of averaging methods compare favorably to field- and laboratory-based values.

  5. On the Importance of Cycle Minimum in Sunspot Cycle Prediction

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.; Hathaway, David H.; Reichmann, Edwin J.

    1996-01-01

    The characteristics of the minima between sunspot cycles are found to provide important information for predicting the amplitude and timing of the following cycle. For example, the time of the occurrence of sunspot minimum sets the length of the previous cycle, which is correlated by the amplitude-period effect to the amplitude of the next cycle, with cycles of shorter (longer) than average length usually being followed by cycles of larger (smaller) than average size (true for 16 of 21 sunspot cycles). Likewise, the size of the minimum at cycle onset is correlated with the size of the cycle's maximum amplitude, with cycles of larger (smaller) than average size minima usually being associated with larger (smaller) than average size maxima (true for 16 of 22 sunspot cycles). Also, it was found that the size of the previous cycle's minimum and maximum relates to the size of the following cycle's minimum and maximum with an even-odd cycle number dependency. The latter effect suggests that cycle 23 will have a minimum and maximum amplitude probably larger than average in size (in particular, minimum smoothed sunspot number Rm = 12.3 +/- 7.5 and maximum smoothed sunspot number RM = 198.8 +/- 36.5, at the 95-percent level of confidence), further suggesting (by the Waldmeier effect) that it will have a faster than average rise to maximum (fast-rising cycles have ascent durations of about 41 +/- 7 months). Thus, if, as expected, onset for cycle 23 will be December 1996 +/- 3 months, based on smoothed sunspot number, then the length of cycle 22 will be about 123 +/- 3 months, inferring that it is a short-period cycle and that cycle 23 maximum amplitude probably will be larger than average in size (from the amplitude-period effect), having an RM of about 133 +/- 39 (based on the usual +/- 30 percent spread that has been seen between observed and predicted values), with maximum amplitude occurrence likely sometime between July 1999 and October 2000.

  6. Effect of daily fluctuations in ambient temperature on reproductive failure traits of Landrace and Yorkshire sows under Thai tropical environmental conditions.

    PubMed

    Jaichansukkit, Teerapong; Suwanasopee, Thanathip; Koonawootrittriron, Skorn; Tummaruk, Padet; Elzo, Mauricio A

    2017-03-01

    The aim of this study was to determine the effects of daily ranges and maximum ambient temperatures, and other risk factors on reproductive failure of Landrace (L) and Yorkshire (Y) sows under an open-house system in Thailand. Daily ambient temperatures were added to information on 35,579 litters from 5929 L sows and 1057 Y sows from three commercial herds. The average daily temperature ranges (ADT) and the average daily maximum temperatures (PEAK) in three gestation periods from the 35th day of gestation to parturition were classified. The considered reproductive failure traits were the occurrences of mummified fetuses (MM), stillborn piglets (STB), and piglet death losses (PDL) and an indicator trait for number of piglets born alive below the population mean (LBA). A multiple logistic regression model included farrowing herd-year-season (HYS), breed group of sow (BG), parity group (PAR), number of total piglets born (NTB), ADT1, ADT2, ADT3, PEAK1, PEAK2, and PEAK3 as fixed effects, while random effects were animal, repeated observations, and residual. Yorkshire sows had a higher occurrence of LBA than L sows (P = 0.01). The second to fifth parities sows had lower reproductive failures than other parities. The NTB regression coefficients of log-odds were positive (P < 0.01) for all traits. Narrower ranges of ADT3 increased the occurrence of MM, STB, and PDL (P < 0.01), while higher PEAK3 increased the occurrence of MM, STB, PDL, and LBA (P < 0.001). To reduce the risk of reproductive failures, particularly late in gestation, producers would need to closely monitor their temperature management strategies.

  7. Statistical downscaling of general-circulation-model- simulated average monthly air temperature to the beginning of flowering of the dandelion (Taraxacum officinale) in Slovenia

    NASA Astrophysics Data System (ADS)

    Bergant, Klemen; Kajfež-Bogataj, Lučka; Črepinšek, Zalika

    2002-02-01

    Phenological observations are a valuable source of information for investigating the relationship between climate variation and plant development. Potential climate change in the future will shift the occurrence of phenological phases. Information about future climate conditions is needed in order to estimate this shift. General circulation models (GCM) provide the best information about future climate change. They are able to simulate reliably the most important mean features on a large scale, but they fail on a regional scale because of their low spatial resolution. A common approach to bridging the scale gap is statistical downscaling, which was used to relate the beginning of flowering of Taraxacum officinale in Slovenia with the monthly mean near-surface air temperature for January, February and March in Central Europe. Statistical models were developed and tested with NCAR/NCEP Reanalysis predictor data and EARS predictand data for the period 1960-1999. Prior to developing statistical models, empirical orthogonal function (EOF) analysis was employed on the predictor data. Multiple linear regression was used to relate the beginning of flowering with expansion coefficients of the first three EOF for the Janauary, Febrauary and March air temperatures, and a strong correlation was found between them. Developed statistical models were employed on the results of two GCM (HadCM3 and ECHAM4/OPYC3) to estimate the potential shifts in the beginning of flowering for the periods 1990-2019 and 2020-2049 in comparison with the period 1960-1989. The HadCM3 model predicts, on average, 4 days earlier occurrence and ECHAM4/OPYC3 5 days earlier occurrence of flowering in the period 1990-2019. The analogous results for the period 2020-2049 are a 10- and 11-day earlier occurrence.

  8. Rapid extraction of image texture by co-occurrence using a hybrid data structure

    NASA Astrophysics Data System (ADS)

    Clausi, David A.; Zhao, Yongping

    2002-07-01

    Calculation of co-occurrence probabilities is a popular method for determining texture features within remotely sensed digital imagery. Typically, the co-occurrence features are calculated by using a grey level co-occurrence matrix (GLCM) to store the co-occurring probabilities. Statistics are applied to the probabilities in the GLCM to generate the texture features. This method is computationally intensive since the matrix is usually sparse leading to many unnecessary calculations involving zero probabilities when applying the statistics. An improvement on the GLCM method is to utilize a grey level co-occurrence linked list (GLCLL) to store only the non-zero co-occurring probabilities. The GLCLL suffers since, to achieve preferred computational speeds, the list should be sorted. An improvement on the GLCLL is to utilize a grey level co-occurrence hybrid structure (GLCHS) based on an integrated hash table and linked list approach. Texture features obtained using this technique are identical to those obtained using the GLCM and GLCLL. The GLCHS method is implemented using the C language in a Unix environment. Based on a Brodatz test image, the GLCHS method is demonstrated to be a superior technique when compared across various window sizes and grey level quantizations. The GLCHS method required, on average, 33.4% ( σ=3.08%) of the computational time required by the GLCLL. Significant computational gains are made using the GLCHS method.

  9. 75 FR 62544 - Proposed Collection; Comment Request; the Atherosclerosis Risk in Communities Study (ARIC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... medical records, and interviews with doctors and family to identify disease occurrence. Interviewers will contact doctors and hospitals to ascertain participants' cardiovascular events. Information gathered will be used to further describe the risk factors, occurrence rates, and consequences of cardiovascular...

  10. An analysis of reported cases of leishmaniasis in the southern Ecuadorian Amazon region, 1986-2012.

    PubMed

    Olalla, Hector R; Velez, Lenin N; Kato, Hirotomo; Hashiguchi, Kazue; Caceres, Abraham G; Gomez, Eduardo A; Zambrano, Flavio C; Romero-Álvarez, Daniel A; Guevara, Angel G; Hashiguchi, Yoshihisa

    2015-06-01

    An analysis of reported cases of cutaneous leishmaniasis (CL) was performed using the data registered in the southern Ecuadorian Amazon region during 27 years from 1986 to 2012. The cases/subjects with both the suspected CL lesions and the amastigote-positive results were recruited for the analysis. The yearly occurrence of cases showed a markedly higher number during the six years, 1988 and 1993. After 1994 when the insecticide spraying campaign using helicopter in 1993-1994, the number dropped remarkably. Then, the yearly occurrence gradually fluctuated from 101 cases in 1996 to 11 in 2009, maintaining a low number of cases after the campaign. The monthly occurrence of cases showed a markedly high number during March and August, suggesting a correlation to the rainy season (months) in the areas. A statistical significance was found between the monthly average number of the CL case and the average precipitation (p=0.01474). It was suggested that the time of transmission of CL would depend on the rainy seasons at each endemic area of Ecuador, which has a diverse climatic feature depending on the geographic regions. Such information at given leishmaniasis-endemic areas of Ecuador would be important for the future planning of the disease control. Molecular analysis and characterization of clinical samples revealed the presence of Leishmania (Viannia) braziliensis. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly

    PubMed Central

    Chen, Liwei; Zhang, Zhenzhen; Chen, Wen; Whelton, Paul K.; Appel, Lawrence J.

    2016-01-01

    Objectives To determine the effect of sodium (Na) reduction on occurrence of headaches. Methods In the Trial of Nonpharmacologic Interventions in the Elderly, 975 men and woman (aged 60–80 years) with hypertension were randomized to a Na-reduction intervention or control group and were followed for up to 36 months. The study was conducted between 1992 and 1995 at 4 clinical centers (Johns Hopkins University, Wake Forest University School of Medicine, Robert Wood Johnson Medical School, and the University of Tennessee). Results Mean difference in Na excretion between the Na-reduction intervention and control group was significant at each follow-up visit (P < .001) with an average difference of 38.8 millimoles per 24 hours. The occurrence of headaches was significantly lower in the Na-reduction intervention group (10.5%) compared with control (14.3%) with a hazard ratio of 0.59 (95% confidence interval = 0.40, 0.88; P = .009). The risk of headaches was significantly associated with average level of Na excretion during follow-up, independent of most recent blood pressure. The relationship appeared to be nonlinear with a spline relationship and a knot at 150 millimoles per 24 hours. Conclusions Reduced sodium intake, currently recommended for blood pressure control, may also reduce the occurrence of headaches in older persons with hypertension. PMID:27077348

  12. Climate anomalies associated with the occurrence of rockfalls at high-elevation in the Italian Alps

    NASA Astrophysics Data System (ADS)

    Paranunzio, Roberta; Laio, Francesco; Chiarle, Marta; Nigrelli, Guido; Guzzetti, Fausto

    2016-09-01

    Climate change is seriously affecting the cryosphere in terms, for example, of permafrost thaw, alteration of rain / snow ratio, and glacier shrinkage. There is concern about the increasing number of rockfalls at high elevation in the last decades. Nevertheless, the exact role of climate parameters in slope instability at high elevation has not been fully explored yet. In this paper, we investigate 41 rockfalls listed in different sources (newspapers, technical reports, and CNR IRPI archive) in the elevation range 1500-4200 m a.s.l. in the Italian Alps between 1997 and 2013 in the absence of an evident trigger. We apply and improve an existing data-based statistical approach to detect the anomalies of climate parameters (temperature and precipitation) associated with rockfall occurrences. The identified climate anomalies have been related to the spatiotemporal distribution of the events. Rockfalls occurred in association with significant temperature anomalies in 83 % of our case studies. Temperature represents a key factor contributing to slope failure occurrence in different ways. As expected, warm temperatures accelerate snowmelt and permafrost thaw; however, surprisingly, negative anomalies are also often associated with slope failures. Interestingly, different regional patterns emerge from the data: higher-than-average temperatures are often associated with rockfalls in the Western Alps, while in the Eastern Alps slope failures are mainly associated with colder-than-average temperatures.

  13. Precipitation data considerations for evaluating subdaily changes in rainless periods due to climate change

    USDA-ARS?s Scientific Manuscript database

    Quantifying magnitudes and frequencies of rainless times between storms (TBS), or storm occurrence, is required for generating continuous sequences of precipitation for modeling inputs to small watershed models for conservation studies. Two parameters characterize TBS, minimum TBS (MTBS) and averag...

  14. Catastrophic health expenditure in households with chronic disease patients: A pre-post comparison of the New Health Care Reform in Shaanxi Province, China

    PubMed Central

    Xu, Yongjian; Ma, Jie; Wu, Na; Fan, Xiaojing; Zhang, Tao; Zhou, Zhongliang; Ren, Jianping; Chen, Gang

    2018-01-01

    Introduction In 2009, China officially launched the New Health Care Reform (NHCR). One important purpose of the reform was to reduce financial burden of health care through health insurance expansion and health care provider regulations. This study aimed to provide evidence on the effect of the NHCR reform on catastrophic health expenditure (CHE) by comparing the occurrence and inequality of CHE among households with chronic diseases patients before and after the reform. Methods This study used the subset of data from the 2008 and 2013 National Health Services Survey conducted in Shaanxi Province. Our sample included households with chronic diseases patients and excluded observations with key variables missing. The final sample size was 1942 households in 2008 and 7704 households in 2013. We defined CHE occurrence following the definition of the World Health Organization (WHO). The income-related inequality in CHE was measured by the concentration index. A multi-level logistic regression model was used in the study to explore the influence of the NHCR on CHE occurrence, controlling for important covariates. Results From 2008 to 2013, the occurrence rate of CHE in rural areas declined from 29.15% to 23.62%. However, the CHE rate in urban areas increased from 19.18% to 24.95%. The interaction term between year and rural/urban location was statistically significant, confirming that the influence of the NHCR on the CHE occurrence rates were heterogeneous between rural and urban areas. As for the CHE inequality, the concentration index in rural areas decreased from -0.4572 to -0.5499 with a p-value less than 0.05. This implied that the CHE occurrence inequality was increased after the implementation of the NHCR. Conclusion Our study suggested that the implementation of the NHCR might not have been effective in reducing the CHE occurrence for households with chronic disease patients. Although the occurrence of CHE of rural households had decreased, the occurrence of CHE in urban areas was higher than before. In addition, the income inequality of CHE occurrence was greater in 2013 compared to that in 2008 in rural areas. Although the reform resulted in higher insurance coverage and higher government expenditure in health care, the financial burden of health care on households did not necessarily improve. Further efforts on developing the current health insurance system and optimizing the hierarchical health care system are required to improve the protection against CHE. PMID:29547654

  15. Individual and Combined Occurrence of Mycotoxins in Feed Ingredients and Complete Feeds in China

    PubMed Central

    Ma, Rui; Zhang, Lei; Liu, Meng; Su, Yong-Teng; Xie, Wen-Mei; Zhang, Ni-Ya; Dai, Jie-Fan; Wang, Yun; Qi, De-Sheng; Karrow, Niel Alexander; Sun, Lv-Hui

    2018-01-01

    The objective of this study was to investigate the individual and combined contamination of aflatoxin B1 (AFB1), zearalenone (ZEN) and deoxynivalenol (DON) in feedstuffs from different Provinces of China between 2016 and 2017. A total of 1569 samples, including 742 feed ingredients and 827 complete pig feed samples, were collected from various regions of China for mycotoxins analysis. The results showed that individual occurrence rates of AFB1, ZEN, and DON were more than 83.3%, 88%, and 74.5%, respectively, in all the tested samples. DON was the most prevalent contaminant, followed by ZEN and AFB1, with the average concentrations ranging from 450.0–4381.5 μg/kg, 2.3–729.2 μg/kg, and 1.3–10.0 μg/kg, respectively. Notable, 38.2%, 10.8%, and 0.6% of complete pig feeds were contaminated with DON, ZEN, and AFB1 over China’s regulatory limits, respectively. Moreover, over 75.0% analyzed samples were co-contaminated with two or three mycotoxins. In conclusion, the current study revealed that the feedstuffs in China were severely contaminated with DON, followed by ZEN and AFB1 during the past two years. These findings highlight the importance of monitoring mycotoxins in livestock feed and implementing feed management and bioremediation strategies to reduce mycotoxin exposure. PMID:29518909

  16. Negative Cognitive Styles Synergistically Predict Suicidal Ideation in Bipolar Spectrum Disorders: A Three-Year Prospective Study

    PubMed Central

    Stange, Jonathan P.; Hamilton, Jessica L.; Burke, Taylor A.; Kleiman, Evan M.; O’Garro-Moore, Jared K.; Seligman, Nicole D.; Abramson, Lyn Y.; Alloy, Lauren B.

    2015-01-01

    Rates of suicidal ideation and behavior are extremely high in Bipolar Spectrum Disorders (BSDs). However, relatively little work has evaluated potentially synergistic relationships between cognitive and emotion-regulatory processes proposed by theoretical models of suicidality in BSDs. The present study evaluated whether negative cognitive style and subtypes of rumination would exacerbate the impact of self-criticism on suicidal ideation in a prospective study of individuals with BSDs. Seventy-two young adults with BSDs (bipolar II, bipolar NOS, or cyclothymia) completed diagnostic interviews and trait measures of self-criticism, negative cognitive style, and brooding and reflective rumination at a baseline assessment. The occurrence of suicidal ideation was assessed as part of diagnostic interviews completed every four months for an average of three years of follow-up. Negative cognitive style and reflective rumination strengthened the association between self-criticism and the prospective occurrence of suicidal ideation across follow-up. Individuals with high levels of self-criticism in conjunction with negative cognitive style or reflective rumination were most likely to experience the onset of suicidal ideation. Self-criticism may work synergistically with negative cognitive style and rumination to confer risk for suicidal ideation in bipolar spectrum disorders. These results support theoretical models of suicidality in BSDs and indicate that evaluating and understanding negative cognitive styles may help to identify individuals who are at risk for suicide. PMID:25660736

  17. Prevalence of Skin Tears in Elderly Patients: A Retrospective Chart Review of Incidence Reports in 6 Long-term Care Facilities.

    PubMed

    Hawk, Joyce; Shannon, Mary

    2018-04-01

    The incidence and prevalence of skin tears in long-term care (LTC) facilities has not been well established. To ascertain the point prevalence of reported skin tears, a retrospective review of incident reports was performed in 6 LTC facilities in western Pennsylvania from November 1, 2016 through December 31, 2016. Report data, including resident age; gender; mobility limitations; skin tear location, number, and cause (if known); occurrence time (7 am to 3 pm, 3 pm to 11 pm, or 11 pm to 7 am nursing shift); and history of previous skin tears, were abstracted. All data were entered into a statistical analysis program and analyzed using descriptive statistics. Period prevalence was used to determine prevalence rate; an independent t test was used to compare the presence of skin tears between genders. Differences between location and cause of skin tears were evaluated using a multinomial test of related proportions. A test of proportions was used to evaluate skin tear occurrence time (nursing shift) differences. The overall point prevalence rate was 9% (N = 1253 residents) ranging from 6 to 28 skin tears per facility. The average age of residents with a skin tear (n = 119) was 83.5 years. The majority (111, 93%) had mobility limitations. Falls accounted for 38 skin tears (31.9%), followed by propelling in a wheelchair (18, 15.1%; X2 =7.14; P = .008). Forearm skin tears (37, 31.1%) occurred significantly more frequently than lower leg skin tears (19, 16%; P = .016). Significantly more skin tears occurred during the 7 am to 3 pm shift (47, 39.5%) and 3 pm to 11 pm shift (49, 41.2%) than during the 11 pm to 7 am shift (23, 19.3%; X2 = 5.78; P <.01). The results of this study confirm skin tears are a significant problem among elderly residents in LTC, especially because the reported rate is likely lower than the actual rate. Research to further elucidate the incidence and prevalence of skin tears and associated risk factors is needed to help develop evidence-based risk assessment, classification systems, treatment guidelines, and preventive measures.

  18. Year-long evaluation on the occurrence and fate of pharmaceuticals, personal care products, and endocrine disrupting chemicals in an urban drinking water treatment plant.

    PubMed

    Padhye, Lokesh P; Yao, Hong; Kung'u, Francis T; Huang, Ching-Hua

    2014-03-15

    The occurrence and removal of thirty representative pharmaceutical and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in an urban drinking water treatment plant (DWTP) were investigated for a period of one year to evaluate current system's treatment efficacy and assess occurrence of PPCPs and EDCs in finished drinking water. Results showed that the average total PPCPs and EDCs concentration in the surface water source was around 360 ng/L (median concentration = 340 ng/L) with 57% coefficient of variation (CV). The median concentrations of most of the individual PPCPs and EDCs in the surface water were below 15 ng/L except for N,N-diethyltoluamide (DEET) and nonylphenol, which were at 122 and 83 ng/L, respectively. The compounds DEET, nonylphenol, ibuprofen, triclosan, atrazine, tris(2-chloroethyl)-phosphate (TCEP), bisphenol-A, and caffeine (in the order of decreasing median concentration) were among twenty compounds detected at least once in the surface water, while all of the above detected compounds, except two, were also detected in the finished drinking water. The average total PPCPs and EDCs concentration in the finished drinking water was around 98 ng/L (median concentration = 96 ng/L) with 66% CV. The median concentrations of most detected PPCPs and EDCs in drinking water were below 5 ng/L except for DEET and nonylphenol, which were at 12 and 20 ng/L, respectively. There was a strong correlation (r = 0.97) between PPCPs and EDCs' concentrations in the source water and in the drinking water over the one-year study period when data points from two sampling events with unusual removals were excluded. Individual water treatment unit processes showed greater temporal variations of PPCPs and EDCs removal efficiencies than the overall treatment processes. The removal efficiencies also varied greatly among different PPCPs and EDCs. The average removal for total PPCPs and EDCs was 76 ± 18% at the DWTP, with ozonation showing the highest removal efficiency. Based on the similar occurrence and removal trends observed as that of total PPCPs and EDCs in this study, DEET and nonylphenol can be considered as potential indicator compounds for predicting the occurrence and removal of total PPCPs and EDCs in surface water. No strong correlations could be found between total PPCPs and EDCs removal and the removal of suspended solids, turbidity, or organic carbon. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Human pharmaceuticals in Portuguese rivers: The impact of water scarcity in the environmental risk.

    PubMed

    Pereira, André M P T; Silva, Liliana J G; Laranjeiro, Célia S M; Meisel, Leonor M; Lino, Celeste M; Pena, Angelina

    2017-12-31

    Pharmaceuticals occurrence and environmental risk assessment were assessed in Portuguese surface waters, evaluating the impact of wastewater treatment plants (WWTPs) and river flow rates. Twenty three pharmaceuticals from 6 therapeutic groups, including metabolites and 1 transformation product, were analysed in 72 samples collected from 20 different sites, upstream and downstream the selected WWTPs, in two different seasons. Analysis was performed by solid phase extraction followed by liquid chromatography coupled to tandem mass spectroscopy. Pharmaceuticals were detected in 27.8% of the samples. Selective serotonin reuptake inhibitors (SSRIs), anti-inflammatories and antibiotics presented the highest detection frequencies (27.8, 23.6 and 23.6%, respectively) and average concentrations (37.9, 36.1 and 33.5ngL -1 , respectively). When assessing the impact of WWTPs, an increase of 21.4% in the average concentrations was observed in the samples located downstream these facilities, when compared with the upstream samples. Increased detection frequencies and concentrations were observed at lower flow rates, both when comparing summer and winter campaigns and by evaluating the different rivers. Risk quotients (RQs) higher than one were found for two pharmaceuticals, concerning two trophic levels. However, since Iberian rivers are highly influenced by water scarcity, in drought periods, the flow rates in these rivers can decrease at least ten times from the lowest value observed in the sampling campaigns. In these conditions, RQs higher than 1 would be observed for 5 pharmaceuticals, additionally, all the detected pharmaceuticals (11) would present RQs higher than 0.1. These results emphasize that the river flow rate represents an important parameter influencing pharmaceuticals concentrations, highlighting the ecotoxicological pressure, especially due to water scarcity in drought periods. This should be a priority issue in the environmental policies for minimizing its impact in the aquatic environment. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Projections of Rapidly Rising Temperatures over Africa Under Low Mitigation

    NASA Technical Reports Server (NTRS)

    Engelbrecht, Francois; Adegoke, Jimmy; Bopape, Mary-Jane; Naidoo, Mogesh; Garland, Rebecca; Thatcher, Marcus; McGregor, John; Katzfe, Jack; Werner, Micha; Ichoku, Charles; hide

    2015-01-01

    An analysis of observed trends in African annual-average near-surface temperatures over the last five decades reveals drastic increases, particularly over parts of the subtropics and central tropical Africa. Over these regions, temperatures have been rising at more than twice the global rate of temperature increase. An ensemble of high-resolution downscalings, obtained using a single regional climate model forced with the sea-surface temperatures and sea-ice fields of an ensemble of global circulation model (GCM) simulations, is shown to realistically represent the relatively strong temperature increases observed in subtropical southern and northern Africa. The amplitudes of warming are generally underestimated, however. Further warming is projected to occur during the 21st century, with plausible increases of 4-6 C over the subtropics and 3-5 C over the tropics by the end of the century relative to present-day climate under the A2 (a low mitigation) scenario of the Special Report on Emission Scenarios. High impact climate events such as heat-wave days and high fire-danger days are consistently projected to increase drastically in their frequency of occurrence. General decreases in soil-moisture availability are projected, even for regions where increases in rainfall are plausible, due to enhanced levels of evaporation. The regional downscalings presented here, and recent GCM projections obtained for Africa, indicate that African annual-averaged temperatures may plausibly rise at about 1.5 times the global rate of temperature increase in the subtropics, and at a somewhat lower rate in the tropics. These projected increases although drastic, may be conservative given the model underestimations of observed temperature trends. The relatively strong rate of warming over Africa, in combination with the associated increases in extreme temperature events, may be key factors to consider when interpreting the suitability of global mitigation targets in terms of African climate change and climate change adaptation in Africa.

  1. Use of anticoagulant or antiplatelet agents is not related to epistaxis in patients undergoing transnasal endoscopy

    PubMed Central

    Kobayashi, Yoshiya; Komazawa, Yoshinori; Yuki, Mika; Ishitobi, Hitomi; Nagaoka, Makoto; Takahashi, Yoshiko; Nakashima, Sayaka; Shizuku, Toshihiro; Kinoshita, Yoshikazu

    2018-01-01

    Background and study aims  Unsedated transnasal endoscopy (uTNE) has become accepted as a safe and tolerable method for upper gastrointestinal tact examinations. Epistaxis is 1 of the major complications of TNE, though its risk factors have not been elucidated. Generally, patients administered an anticoagulant or antiplatelet drug are considered to have an increased risk of epistaxis during TNE. Here, we investigated risk factors of epistaxis in patients undergoing uTNE, with focus on those who received antithrombotic agents. Patients and methods  We enrolled 6860 patients (average age 55.6 ± 12.97 years; 3405 males, 3455 females) who underwent uTNE and received the same preparations for the procedure. Epistaxis was evaluated using endoscopic images obtained while withdrawing the scope through the nostril. We also noted current use of medications including anticoagulant or antiplatelet agents prior to the endoscopic examination. Results  Epistaxis occurred in 3.6 % of the enrolled patients (245/6860), and that rate was significantly higher in younger patients (average age 49.31 ± 11.8 years for epistaxis group vs. 55.83 ± 13.0 years for no epistaxis group, P  < 0.01) as well as females (4.78 % vs. 2.35 %, P  < 0.01). The odds ratio for occurrence of epistaxis was 2.31 (95 %CI: 1.746 – 3.167) in the younger patients and 2.02 (95 % CI: 1.542 – 2.659) in females. In contrast, there was no significant difference for rate of epistaxis between patients with and without treatment with an antithrombotic agent (3.0 % vs. 3.6 %). Conclusions  The rate of epistaxis was higher in younger and female patients. Importantly, that rate was not significantly increased in patients who were administered an antithrombotic agent. PMID:29344570

  2. Environmentally critical elements in channel and cleaned samples of Illinois coals

    USGS Publications Warehouse

    Demir, I.; Ruch, R.R.; Damberger, H.H.; Harvey, R.D.; Steele, J.D.; Ho, K.K.

    1998-01-01

    Sixteen trace and minor elements that occur in coal are listed among 189 substances identified as 'hazardous air pollutants' (HAPs) in the US Clean Air Act Amendments of 1990. We investigated the occurrence and cleanability of the 16 HAPs in Illinois coals, as a contribution to the discussion about the potential effect of pending environmental regulations on the future use of these coals in power generation. The average ash content of the samples of conventionally cleaned as-shipped coals is about 20% lower than that of standard channel samples. Conventional cleaning reduces the average concentrations of As, Cd, Co, Hg, Mn, Ni, Pb, Sb and Th in the as-shipped coals by more than 20% relative to channel samples. Thus, basing assessments of health risks from emissions of HAPs during coal combustion on channel samples without appropriate adjustment would overestimate the risk. Additional cleaning by froth-flotation reduces the ash content of finely-ground as-shipped coals by as much as 76% at an 80% combustibles recovery. Although the average froth-flotation cleanability for the majority of HAPs is less than that for ash, the cleanabilities in some individual cases approaches, or even exceeds, the cleanability for ash, depending on the modes of occurrences of the elements. ?? 1997 Elsevier Science Ltd.

  3. Market Correlation Structure Changes Around the Great Crash: A Random Matrix Theory Analysis of the Chinese Stock Market

    NASA Astrophysics Data System (ADS)

    Han, Rui-Qi; Xie, Wen-Jie; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

    The correlation structure of a stock market contains important financial contents, which may change remarkably due to the occurrence of financial crisis. We perform a comparative analysis of the Chinese stock market around the occurrence of the 2008 crisis based on the random matrix analysis of high-frequency stock returns of 1228 Chinese stocks. Both raw correlation matrix and partial correlation matrix with respect to the market index in two time periods of one year are investigated. We find that the Chinese stocks have stronger average correlation and partial correlation in 2008 than in 2007 and the average partial correlation is significantly weaker than the average correlation in each period. Accordingly, the largest eigenvalue of the correlation matrix is remarkably greater than that of the partial correlation matrix in each period. Moreover, each largest eigenvalue and its eigenvector reflect an evident market effect, while other deviating eigenvalues do not. We find no evidence that deviating eigenvalues contain industrial sectorial information. Surprisingly, the eigenvectors of the second largest eigenvalues in 2007 and of the third largest eigenvalues in 2008 are able to distinguish the stocks from the two exchanges. We also find that the component magnitudes of the some largest eigenvectors are proportional to the stocks’ capitalizations.

  4. Spatial distribution and source apportionment of PFASs in surface sediments from five lake regions, China.

    PubMed

    Qi, Yanjie; Huo, Shouliang; Xi, Beidou; Hu, Shibin; Zhang, Jingtian; He, Zhuoshi

    2016-03-07

    Perfluoroalkyl substances (PFASs) have been found in environment globally. However, studies on PFAS occurrence in sediments of lakes or reservoirs remain relatively scarce. In this study, two hundred and sixty-two surface sediment samples were collected from forty-eight lakes and two reservoirs all over China. Average PFAS concentrations in surface sediments from each lake or reservoir varied from 0.086 ng/g dw to 5.79 ng/g dw with an average of 1.15 ng/g dw. Among five lake regions, average PFAS concentrations for the lakes from Eastern Plain Region were the highest. Perfluorooctanoic acid, perfluoroundecanoic acid and perfluorooctane sulfonic acid (PFOS) were the predominant PFASs in surface sediments. The significant positive correlations between PFAS concentrations and total organic carbon, total nitrogen and total phosphorus contents in sediments revealed the influences of sedimentary characteristics on PFAS occurrence. A two-dimensional hierarchical cluster analysis heat map was depicted to analyze the possible origins of sediments and individual PFAS. The food-packaging, textile, electroplating, firefighting and semiconductor industry emission sources and the precious metals and coating industry emission sources were identified as the main sources by two receptor models, with contributions of 77.7 and 22.3% to the total concentrations of C4-C14- perfluoroalkyl carboxylic acids and PFOS, respectively.

  5. Spatial distribution and source apportionment of PFASs in surface sediments from five lake regions, China

    NASA Astrophysics Data System (ADS)

    Qi, Yanjie; Huo, Shouliang; Xi, Beidou; Hu, Shibin; Zhang, Jingtian; He, Zhuoshi

    2016-03-01

    Perfluoroalkyl substances (PFASs) have been found in environment globally. However, studies on PFAS occurrence in sediments of lakes or reservoirs remain relatively scarce. In this study, two hundred and sixty-two surface sediment samples were collected from forty-eight lakes and two reservoirs all over China. Average PFAS concentrations in surface sediments from each lake or reservoir varied from 0.086 ng/g dw to 5.79 ng/g dw with an average of 1.15 ng/g dw. Among five lake regions, average PFAS concentrations for the lakes from Eastern Plain Region were the highest. Perfluorooctanoic acid, perfluoroundecanoic acid and perfluorooctane sulfonic acid (PFOS) were the predominant PFASs in surface sediments. The significant positive correlations between PFAS concentrations and total organic carbon, total nitrogen and total phosphorus contents in sediments revealed the influences of sedimentary characteristics on PFAS occurrence. A two-dimensional hierarchical cluster analysis heat map was depicted to analyze the possible origins of sediments and individual PFAS. The food-packaging, textile, electroplating, firefighting and semiconductor industry emission sources and the precious metals and coating industry emission sources were identified as the main sources by two receptor models, with contributions of 77.7 and 22.3% to the total concentrations of C4-C14- perfluoroalkyl carboxylic acids and PFOS, respectively.

  6. 47 CFR 64.1801 - Geographic rate averaging and rate integration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Geographic rate averaging and rate integration. 64.1801 Section 64.1801 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... Rate Integration § 64.1801 Geographic rate averaging and rate integration. (a) The rates charged by...

  7. Multi-hazard Assessment and Scenario Toolbox (MhAST): A Framework for Analyzing Compounding Effects of Multiple Hazards

    NASA Astrophysics Data System (ADS)

    Sadegh, M.; Moftakhari, H.; AghaKouchak, A.

    2017-12-01

    Many natural hazards are driven by multiple forcing variables, and concurrence/consecutive extreme events significantly increases risk of infrastructure/system failure. It is a common practice to use univariate analysis based upon a perceived ruling driver to estimate design quantiles and/or return periods of extreme events. A multivariate analysis, however, permits modeling simultaneous occurrence of multiple forcing variables. In this presentation, we introduce the Multi-hazard Assessment and Scenario Toolbox (MhAST) that comprehensively analyzes marginal and joint probability distributions of natural hazards. MhAST also offers a wide range of scenarios of return period and design levels and their likelihoods. Contribution of this study is four-fold: 1. comprehensive analysis of marginal and joint probability of multiple drivers through 17 continuous distributions and 26 copulas, 2. multiple scenario analysis of concurrent extremes based upon the most likely joint occurrence, one ruling variable, and weighted random sampling of joint occurrences with similar exceedance probabilities, 3. weighted average scenario analysis based on a expected event, and 4. uncertainty analysis of the most likely joint occurrence scenario using a Bayesian framework.

  8. Atmospheric oxidation of 1,3-butadiene: characterization of gas and aerosol reaction products and implication for PM2.5

    NASA Astrophysics Data System (ADS)

    Jaoui, M.; Lewandowski, M.; Docherty, K.; Offenberg, J. H.; Kleindienst, T. E.

    2014-06-01

    Secondary organic aerosol (SOA) was generated by irradiating 1,3-butadiene (13BD) in the presence of H2O2 or NOx. Experiments were conducted in a smog chamber operated in either flow or batch mode. A filter/denuder sampling system was used for simultaneously collecting gas- and particle-phase products. The chemical composition of the gas phase and SOA was analyzed using derivative-based methods (BSTFA, BSTFA + PFBHA, or DNPH) followed by gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography (HPLC) analysis of the derivative compounds. The analysis showed the occurrence of more than 60 oxygenated organic compounds in the gas and particle phases, of which 31 organic monomers were tentatively identified. The major identified products include glyceric acid, d-threitol, erythritol, d-threonic acid, meso-threonic acid, erythrose, malic acid, tartaric acid, and carbonyls including glycolaldehyde, glyoxal, acrolein, malonaldehyde, glyceraldehyde, and peroxyacryloyl nitrate (APAN). Some of these were detected in ambient PM2.5 samples and could potentially serve as organic markers of 1,3-butadiene (13BD). Furthermore, a series of oligoesters were detected and found to be produced from esterification reactions among compounds bearing alcoholic groups and compounds bearing acidic groups. Time profiles are provided for selected compounds. SOA was analyzed for organic mass to organic carbon (OM / OC) ratio, effective enthalpy of vaporization (ΔHvapeff), and aerosol yield. The average OM / OC ratio and SOA density were 2.7 ± 0.09 and 1.2 ± 0.05, respectively. The average ΔHvapeff was 26.1 ± 1.5 kJ mol-1, a value lower than that of isoprene SOA. The average laboratory SOA yield measured in this study at aerosol mass concentrations between 22.5 and 140.2 μg m-3 was 0.025 ± 0.011, a value consistent with the literature (0.021-0.178). While the focus of this study has been examination of the particle-phase measurements, the gas-phase photooxidation products have also been examined. The contribution of SOA products from 13BD oxidation to ambient PM2.5 was investigated by analyzing a series of ambient PM2.5 samples collected in several locations around the United States. In addition to the occurrence of several organic compounds in field and laboratory samples, glyceric acid, d-threitol, erythritol, erythrose, and threonic acid were found to originate only from the oxidation of 13BD based on our previous experiments involving chamber oxidation of a series of hydrocarbons. Initial attempts have been made to quantify the concentrations of these compounds. The average concentrations of these compounds in ambient PM2.5 samples from the California Research at the Nexus of Air Quality and Climate Change (CalNex) study ranged from 0 to approximately 14.1 ng m-3. The occurrence of several other compounds in both laboratory and field samples suggests that SOA originating from 13BD oxidation could contribute to the ambient aerosol mainly in areas with high 13BD emission rates.

  9. Atmospheric oxidation of 1,3-butadiene: characterization of gas and aerosol reaction products and implications for PM2.5

    NASA Astrophysics Data System (ADS)

    Jaoui, M.; Lewandowski, M.; Docherty, K.; Offenberg, J. H.; Kleindienst, T. E.

    2014-12-01

    Secondary organic aerosol (SOA) was generated by irradiating 1,3-butadiene (13BD) in the presence of H2O2 or NOx. Experiments were conducted in a smog chamber operated in either flow or batch mode. A filter/denuder sampling system was used for simultaneously collecting gas- and particle-phase products. The chemical composition of the gas phase and SOA was analyzed using derivative-based methods (BSTFA, BSTFA + PFBHA, or DNPH) followed by gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography (HPLC) analysis of the derivative compounds. The analysis showed the occurrence of more than 60 oxygenated organic compounds in the gas and particle phases, of which 31 organic monomers were tentatively identified. The major identified products include glyceric acid, d-threitol, erythritol, d-threonic acid, meso-threonic acid, erythrose, malic acid, tartaric acid, and carbonyls including glycolaldehyde, glyoxal, acrolein, malonaldehyde, glyceraldehyde, and peroxyacryloyl nitrate (APAN). Some of these were detected in ambient PM2.5 samples, and could potentially serve as organic markers of 13BD. Furthermore, a series of oligoesters were detected and found to be produced through chemical reactions occurring in the aerosol phase between compounds bearing alcoholic groups and compounds bearing acidic groups. SOA was analyzed for organic mass to organic carbon (OM /OC) ratio, effective enthalpy of vaporization (Δ Hvapeff), and aerosol yield. The average OM /OC ratio and SOA density were 2.7 ± 0.09 and 1.2 ± 0.05, respectively. The average Δ Hvapeff was -26.08 ± 1.46 kJ mol-1, a value lower than that of isoprene SOA. The average laboratory SOA yield measured in this study at aerosol mass concentrations between 22.5 and 140.2 μg m-3 was 0.025 ± 0.011, a value consistent with the literature (0.021-0.178). While the focus of this study has been examination of the particle-phase measurements, the gas-phase photooxidation products have also been examined. The contribution of SOA products from 13BD oxidation to ambient PM2.5 was investigated by analyzing a series of ambient PM2.5 samples collected in several locations around the United States. In addition to the occurrence of several organic compounds in field and laboratory samples, glyceric acid, d-threitol, erythritol, erythrose, and threonic acid were found to originate only from the oxidation of 13BD based on our previous experiments involving chamber oxidation of a series of hydrocarbons. Initial attempts have been made to quantify the concentrations of these compounds. The average concentrations of these compounds in ambient PM2.5 samples from the California Research at the Nexus of Air Quality and Climate Change (CalNex) study ranged from 0 to approximately 14.1 ng m-3. The occurrence of several other compounds in both laboratory and field samples suggests that SOA originating from 13BD oxidation could contribute to the ambient aerosol mainly in areas with high 13BD emission rates.

  10. Dobutamine stress MRI. Part II. Risk stratification with dobutamine cardiovascular magnetic resonance in patients suspected of myocardial ischemia.

    PubMed

    Kuijpers, Dirkjan; van Dijkman, Paul R M; Janssen, Caroline H C; Vliegenthart, Rozemarijn; Zijlstra, Felix; Oudkerk, Matthijs

    2004-11-01

    The aim of this study was to determine the prognostic value of dobutamine cardiovascular magnetic resonance (CMR) in patients suspected of myocardial ischemia. Clinical data and dobutamine-CMR results were analyzed in 299 consecutive patients. Follow-up data were analyzed in categories of risk levels defined by the history of coronary artery disease and presence of rest wall motion abnormalities (RWMA). Major adverse cardiac events (MACE) as evaluated end points included cardiac death, nonfatal myocardial infarction and clinically indicated coronary revascularization. Follow-up was completed in 214 (99%) patients with a negative dobutamine-CMR study (no signs of inducible myocardial ischemia) with an average of 24 months. The patients with a negative dobutamine-CMR study and RWMA showed a significantly higher annual MACE rate (18%) than the patients without RWMA (0.56%) ( P<0.001). Patients without RWMA showed an annual MACE rate of 2% when they had a history of coronary artery disease and <0.1% without a previous coronary event ( P<0.001). Dobutamine-CMR showed a positive and negative predictive value of 95 and 93%, respectively. The cardiovascular occurrence-free survival rate was 96.2%. In patients suspected of myocardial ischemia, dobutamine-CMR is able to assess risk levels for coronary events with high accuracy.

  11. Geodetic measurement of deformation in the central Mojave Desert, California

    NASA Technical Reports Server (NTRS)

    Sauber, Jeanne; Solomon, Sean C.; Thatcher, Wayne

    1986-01-01

    Data from triangulation and trilateration surveys made during 1934-1982 are used to calculate shear strain rates in the central Mojave Desert of California. For the region between the Helendale and Camp Rock faults the shear strain rate was determined to be 0.16 + or - 0.03 microstrain/yr, with maximum right-lateral shear strain occurring on a plane oriented N41 deg W + or - 5 deg. If this deformation is due to right-lateral motion across the northwest trending local faults, the average shear straining corresponds to a relative displacement of 6.7 + or - 1.3 mm/yr across this portion of the network, accounting for about 12 percent of the predicted 56 mm/yr of relative motion between the North Atlantic and Pacific plates. From the Camp Rock fault eastward across the network there is a transition from significant to very low strain rates. Examination of nine focal mechanisms and their relation to the local geology and the strain data suggests that most of the long-term displacement occurs on the major northwest trending faults oriented nearly along the direction of relative motion between the North American and Pacific plates. Secondary faulting, controlled by a Coulomb-Anderson failure mechanism or by slip on preexisting faults can account for the occurrence of earthquakes on faults of other orientations.

  12. Vertical migration of aggregated aerobic and anaerobic ammonium oxidizers enhances oxygen uptake in a stagnant water layer.

    PubMed

    Vlaeminck, Siegfried E; Dierick, Katleen; Boon, Nico; Verstraete, Willy

    2007-07-01

    Ammonium can be removed as dinitrogen gas by cooperating aerobic and anaerobic ammonium-oxidizing bacteria (AerAOB and AnAOB). The goal of this study was to verify putative mutual benefits for aggregated AerAOB and AnAOB in a stagnant freshwater environment. In an ammonium fed water column, the biological oxygen consumption rate was, on average, 76 kg O(2) ha(-1) day(-1). As the oxygen transfer rate of an abiotic control column was only 17 kg O(2) ha(-1) day(-1), biomass activity enhanced the oxygen transfer. Increasing the AnAOB gas production increased the oxygen consumption rate with more than 50% as a result of enhanced vertical movement of the biomass. The coupled decrease in dissolved oxygen concentration increased the diffusional oxygen transfer from the atmosphere in the water. Physically preventing the biomass from rising to the upper water layer instantaneously decreased oxygen and ammonium consumption and even led to the occurrence of some sulfate reduction. Floating of the biomass was further confirmed to be beneficial, as this allowed for the development of a higher AerAOB and AnAOB activity, compared to settled biomass. Overall, the results support mutual benefits for aggregated AerAOB and AnAOB, derived from the biomass uplifting effect of AnAOB gas production.

  13. Myxomatosis: the occurrence of antibody to a soluble antigen of myxoma virus in wild rabbits, Oryctolagus cuniculus (L.), in Victoria, Australia.

    PubMed Central

    Edmonds, J. W.; Shepherd, R. C.; Nolan, I. F.

    1978-01-01

    The occurrence of antibody of myxoma virus in wild rabbits following epizootics is highest in the semi-arid north-west of Victoria and lowest in temperate southern Victoria. Occurrence ranges up to about 90% in the north-west and to about 70% in the south except on the Western Plains where epizootics are rare and antibody occurrence seldom exceeds 30%. The establishment of the European rabbit flea may be changing the pattern of occurrence of antibody in the north-west by causing spring outbreaks of myxomatosis. It is suggested that the effects of the replacement of a simple recurring system of epizootic and breeding season several months apart by the occurrence of myxomatosis twice in the same year, once coincident with the breeding season, will be complex. The occurrence of detectable antibody may be less dependent on the infection rate and may be dependent to some extent on the relative timing of spring myxomatosis and the breeding season. PMID:701788

  14. Myxomatosis: the occurrence of antibody to a soluble antigen of myxoma virus in wild rabbits, Oryctolagus cuniculus (L.), in Victoria, Australia.

    PubMed

    Edmonds, J W; Shepherd, R C; Nolan, I F

    1978-10-01

    The occurrence of antibody of myxoma virus in wild rabbits following epizootics is highest in the semi-arid north-west of Victoria and lowest in temperate southern Victoria. Occurrence ranges up to about 90% in the north-west and to about 70% in the south except on the Western Plains where epizootics are rare and antibody occurrence seldom exceeds 30%. The establishment of the European rabbit flea may be changing the pattern of occurrence of antibody in the north-west by causing spring outbreaks of myxomatosis. It is suggested that the effects of the replacement of a simple recurring system of epizootic and breeding season several months apart by the occurrence of myxomatosis twice in the same year, once coincident with the breeding season, will be complex. The occurrence of detectable antibody may be less dependent on the infection rate and may be dependent to some extent on the relative timing of spring myxomatosis and the breeding season.

  15. Characteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients.

    PubMed

    Nakagawa, Kenichiro; Koike, Tomoyuki; Iijima, Katsunori; Saito, Masahiro; Kikuchi, Hiroki; Hatta, Waku; Ara, Nobuyuki; Uno, Kaname; Asano, Naoki; Shimosegawa, Tooru

    2015-12-21

    To clarify the pathogenesis of gastroesophageal reflux disease symptoms in non-erosive reflux disease (NERD) patients. Thirty-five NERD patients with persistent symptoms, despite taking rabeprazole 10 mg twice daily for at least 8 wk, were included in this study. All patients underwent 24 h combined impedance - pH on rabeprazole. The symptom index (SI) was considered to be positive if ≥ 50%, and proximal reflux episodes were determined when reflux reached 15 cm above the proximal margin of the lower esophageal sphincter. In 14 (40%) SI-positive patients, with liquid weakly acid reflux, the occurrence rate of reflux symptoms was significantly more frequent in proximal reflux episodes (46.7%) than in distal ones (5.7%) (P < 0.001). With liquid acid reflux, there were no significant differences in the occurrence rate of reflux symptoms between proximal reflux episodes (38.5%) and distal ones (20.5%) (NS). With mixed liquid-gas weakly acid reflux, the occurrence rate of reflux symptoms in proximal reflux episodes was significantly more frequent (31.0%) than in distal reflux ones (3.3%) (P < 0.001). With mixed liquid-gas acid reflux, there were no significant differences in the occurrence rate of reflux symptoms between proximal reflux episodes (29.4%) and distal ones (14.3%) (NS). The proximal extent of weakly acidic liquid and mixed liquid-gas reflux is a major factor associated with reflux perception in SI-positive patients on proton pump inhibitor therapy.

  16. Characteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients

    PubMed Central

    Nakagawa, Kenichiro; Koike, Tomoyuki; Iijima, Katsunori; Saito, Masahiro; Kikuchi, Hiroki; Hatta, Waku; Ara, Nobuyuki; Uno, Kaname; Asano, Naoki; Shimosegawa, Tooru

    2015-01-01

    AIM: To clarify the pathogenesis of gastroesophageal reflux disease symptoms in non-erosive reflux disease (NERD) patients. METHODS: Thirty-five NERD patients with persistent symptoms, despite taking rabeprazole 10 mg twice daily for at least 8 wk, were included in this study. All patients underwent 24 h combined impedance - pH on rabeprazole. The symptom index (SI) was considered to be positive if ≥ 50%, and proximal reflux episodes were determined when reflux reached 15 cm above the proximal margin of the lower esophageal sphincter. RESULTS: In 14 (40%) SI-positive patients, with liquid weakly acid reflux, the occurrence rate of reflux symptoms was significantly more frequent in proximal reflux episodes (46.7%) than in distal ones (5.7%) (P < 0.001). With liquid acid reflux, there were no significant differences in the occurrence rate of reflux symptoms between proximal reflux episodes (38.5%) and distal ones (20.5%) (NS). With mixed liquid-gas weakly acid reflux, the occurrence rate of reflux symptoms in proximal reflux episodes was significantly more frequent (31.0%) than in distal reflux ones (3.3%) (P < 0.001). With mixed liquid-gas acid reflux, there were no significant differences in the occurrence rate of reflux symptoms between proximal reflux episodes (29.4%) and distal ones (14.3%) (NS). CONCLUSION: The proximal extent of weakly acidic liquid and mixed liquid-gas reflux is a major factor associated with reflux perception in SI-positive patients on proton pump inhibitor therapy. PMID:26715820

  17. Modeling nonbreeding distributions of shorebirds and waterfowl in response to climate change

    USGS Publications Warehouse

    Reese, Gordon; Skagen, Susan K.

    2017-01-01

    To identify areas on the landscape that may contribute to a robust network of conservation areas, we modeled the probabilities of occurrence of several en route migratory shorebirds and wintering waterfowl in the southern Great Plains of North America, including responses to changing climate. We predominantly used data from the eBird citizen-science project to model probabilities of occurrence relative to land-use patterns, spatial distribution of wetlands, and climate. We projected models to potential future climate conditions using five representative general circulation models of the Coupled Model Intercomparison Project 5 (CMIP5). We used Random Forests to model probabilities of occurrence and compared the time periods 1981–2010 (hindcast) and 2041–2070 (forecast) in “model space.” Projected changes in shorebird probabilities of occurrence varied with species-specific general distribution pattern, migration distance, and spatial extent. Species using the western and northern portion of the study area exhibited the greatest likelihoods of decline, whereas species with more easterly occurrences, mostly long-distance migrants, had the greatest projected increases in probability of occurrence. At an ecoregional extent, differences in probabilities of shorebird occurrence ranged from −0.015 to 0.045 when averaged across climate models, with the largest increases occurring early in migration. Spatial shifts are predicted for several shorebird species. Probabilities of occurrence of wintering Mallards and Northern Pintail are predicted to increase by 0.046 and 0.061, respectively, with northward shifts projected for both species. When incorporated into partner land management decision tools, results at ecoregional extents can be used to identify wetland complexes with the greatest potential to support birds in the nonbreeding season under a wide range of future climate scenarios.

  18. Attitudes of Mashhad Public Hospital's Nurses and Midwives toward the Causes and Rates of Medical Errors Reporting.

    PubMed

    Mobarakabadi, Sedigheh Sedigh; Ebrahimipour, Hosein; Najar, Ali Vafaie; Janghorban, Roksana; Azarkish, Fatemeh

    2017-03-01

    Patient's safety is one of the main objective in healthcare services; however medical errors are a prevalent potential occurrence for the patients in treatment systems. Medical errors lead to an increase in mortality rate of the patients and challenges such as prolonging of the inpatient period in the hospitals and increased cost. Controlling the medical errors is very important, because these errors besides being costly, threaten the patient's safety. To evaluate the attitudes of nurses and midwives toward the causes and rates of medical errors reporting. It was a cross-sectional observational study. The study population was 140 midwives and nurses employed in Mashhad Public Hospitals. The data collection was done through Goldstone 2001 revised questionnaire. SPSS 11.5 software was used for data analysis. To analyze data, descriptive and inferential analytic statistics were used. Standard deviation and relative frequency distribution, descriptive statistics were used for calculation of the mean and the results were adjusted as tables and charts. Chi-square test was used for the inferential analysis of the data. Most of midwives and nurses (39.4%) were in age range of 25 to 34 years and the lowest percentage (2.2%) were in age range of 55-59 years. The highest average of medical errors was related to employees with three-four years of work experience, while the lowest average was related to those with one-two years of work experience. The highest average of medical errors was during the evening shift, while the lowest were during the night shift. Three main causes of medical errors were considered: illegibile physician prescription orders, similarity of names in different drugs and nurse fatigueness. The most important causes for medical errors from the viewpoints of nurses and midwives are illegible physician's order, drug name similarity with other drugs, nurse's fatigueness and damaged label or packaging of the drug, respectively. Head nurse feedback, peer feedback, fear of punishment or job loss were considered as reasons for under reporting of medical errors. This research demonstrates the need for greater attention to be paid to the causes of medical errors.

  19. Outcome and cervical metastatic spread of squamous cell cancer of the buccal mucosa, a retrospective analysis of the past 25 years.

    PubMed

    Sagheb, Keyvan; Blatt, Sebastian; Kraft, Ina Sophie; Zimmer, Stefanie; Rahimi-Nedjat, Roman-Kia; Al-Nawas, Bilal; Walter, Christian

    2017-07-01

    Because of the low proportion of squamous cell carcinomas (SCCs) of the buccal mucosa within the carcinomas of the oral cavity in the Western population, data concerning metastatic pattern are sparse. Therefore, this retrospective study is focusing on the occurrence of cervical metastases (CM) and the overall outcome of this tumor entity. From January 1988 to October 2013, 113 patients were treated in the Department of Oral and Maxillofacial Surgery, Mainz, for an oral SCC of the cheek. Metastatic pattern and clinical parameters that are possibly associated with an increased risk for CM as well as overall outcome were analyzed. The average follow-up was 48 months (range: 1-248 months). A total of 55 (49%) patients were female and 58 (51%) male, with an average age of 65 ± 13 years (♀68 ± 14 years; ♂63 ± 11 years). In total, 55% of the patients either smoked and/or consumed alcohol. In total, 34% of the patients had a stage III or IV tumor, with overall 23% having CM at the time of diagnosis. During the follow-up, 50% (n = 56) of the patients developed a relapse after 12 months (median). Tumor size (P = 0.002*) and grading (P < 0.001*) are significantly associated with the occurrence of CM. Metastases (P = 0.008*) and advanced tumor size (P = 0.018) had an influence on the survival, whereas the relapse had no significant influence (P = 0.928). Five-year survival rate was 80%. SCC of the buccal mucosa shows aggressive behavior with a considerably high proportion of relapse. Since overall outcome is significantly decreased by the cervical metastatic pattern, a selective, ipsilateral neck dissection for this patient group is recommended as the primary management. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. 48 CFR 9904.416-60 - Illustrations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... physical units of property and the average potential loss per unit is relatively low, the actual losses in...-insurance charge for such losses, then any difference between the self-insurance charge and actual losses in... potential loss per occurrence is limited, the actual losses in any cost accounting period may be expected...

  1. A Scheme for Text Analysis Using Fortran.

    ERIC Educational Resources Information Center

    Koether, Mary E.; Coke, Esther U.

    Using string-manipulation algorithms, FORTRAN computer programs were designed for analysis of written material. The programs measure length of a text and its complexity in terms of the average length of words and sentences, map the occurrences of keywords or phrases, calculate word frequency distribution and certain indicators of style. Trials of…

  2. Theater-Level Stochastic Air-to-Air Engagement Modeling via Event Occurrence Networks Using Piecewise Polynomial Approximation

    DTIC Science & Technology

    2001-09-01

    diagnosis natural language understanding circuit fault diagnosis pattern recognition machine vision nancial auditing map learning sensor... ACCA ACCB A ights degree of command and control FCC value is assumed to be the average of all the ACC values of the aircraft in the

  3. Pan-Planets: Searching for hot Jupiters around cool dwarfs

    NASA Astrophysics Data System (ADS)

    Obermeier, C.; Koppenhoefer, J.; Saglia, R. P.; Henning, Th.; Bender, R.; Kodric, M.; Deacon, N.; Riffeser, A.; Burgett, W.; Chambers, K. C.; Draper, P. W.; Flewelling, H.; Hodapp, K. W.; Kaiser, N.; Kudritzki, R.-P.; Magnier, E. A.; Metcalfe, N.; Price, P. A.; Sweeney, W.; Wainscoat, R. J.; Waters, C.

    2016-03-01

    The Pan-Planets survey observed an area of 42 sq deg. in the galactic disk for about 165 h. The main scientific goal of the project is the detection of transiting planets around M dwarfs. We establish an efficient procedure for determining the stellar parameters Teff and log g of all sources using a method based on SED fitting, utilizing a three-dimensional dust map and proper motion information. In this way we identify more than 60 000 M dwarfs, which is by far the largest sample of low-mass stars observed in a transit survey to date. We present several planet candidates around M dwarfs and hotter stars that are currently being followed up. Using Monte Carlo simulations we calculate the detection efficiency of the Pan-Planets survey for different stellar and planetary populations. We expect to find 3.0+3.3-1.6 hot Jupiters around F, G, and K dwarfs with periods lower than 10 days based on the planet occurrence rates derived in previous surveys. For M dwarfs, the percentage of stars with a hot Jupiter is under debate. Theoretical models expect a lower occurrence rate than for larger main sequence stars. However, radial velocity surveys find upper limits of about 1% due to their small sample, while the Kepler survey finds a occurrence rate that we estimate to be at least 0.17b(+0.67-0.04) %, making it even higher than the determined fraction from OGLE-III for F, G and K stellar types, 0.14 (+0.15-0.076) %. With the large sample size of Pan-Planets, we are able to determine an occurrence rate of 0.11 (+0.37-0.02) % in case one of our candidates turns out to be a real detection. If, however, none of our candidates turn out to be true planets, we are able to put an upper limit of 0.34% with a 95% confidence on the hot Jupiter occurrence rate of M dwarfs. This limit is a significant improvement over previous estimates where the lowest limit published so far is 1.1% found in the WFCAM Transit Survey. Therefore we cannot yet confirm the theoretical prediction of a lower occurrence rate for cool stars. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  4. RELATIONSHIPs among Geomagnetic storms, interplanetary shocks, magnetic clouds, and SUNSPOT NUMBER during 1995-2012

    NASA Astrophysics Data System (ADS)

    Berdichevsky, D. B.; Lepping, R. P.; Wu, C. C.

    2015-12-01

    During 1995-2012 Wind recorded 168 magnetic clouds (MCs), 197 magnetic cloud-like structures (MCLs), and 358 interplanetary (IP) shocks. Ninety four MCs and 56 MCLs had upstream shock waves. The following features are found: (i) Averages of solar wind speed, interplanetary magnetic field (IMF), duration (<Δt>), strength of Bzmin, and intensity of the associated geomagnetic storm/activity (Dstmin) for MCs with upstream shock waves (MCSHOCK) are higher (or stronger) than those averages for the MCs without upstream shock waves (MCNO-SHOCK). (ii) The <Δt> of MCSHOCK events (≈19.6 hr) is 9% longer than that for MCNO-SHOCK events (≈17.9 hr). (iii) For the MCSHOCK events, the average duration of the sheath (<ΔtSHEATH>) is 12.1 hrs. These findings could be very useful for space weather predictions, i.e. IP shocks driven by MCs are expected to arrive at Wind (or at 1 AU) about ~12 hours ahead of the front of the MCs on average. (iv) The occurrence frequency of IP shocks is well associated with sunspot number (SSN). The average intensity of geomagnetic storms measured by for MCSHOCK and MCNOSHOCK events is -102 and -31 nT, respectively. The is -78, -70, and -35 nT for the 358 IP shocks, 168 MCs, and 197 MCLs, respectively. These results imply that IP shocks, when they occur with MCs/MCLs, must play an important role in the strength of geomagnetic storms. We speculate as to why this is so. Yearly occurrence frequencies of MCSHOCK and IP shocks are well correlated with solar activity (e.g., SSN). Choosing the right Dstmin estimating formula for predicting the intensity of MC-associated geomagnetic storms is crucial for space weather predictions.

  5. Recent (circa 1998 to 2011) channel-migration rates of selected streams in Indiana

    USGS Publications Warehouse

    Robinson, Bret A.

    2013-01-01

    An investigation was completed to document recent (circa 1998 to 2011) channel-migration rates at 970 meander bends along 38 of the largest streams in Indiana. Data collection was completed by using the Google Earth™ platform and, for each selected site, identifying two images with capture dates separated by multiple years. Within each image, the position of the meander-bend cutbank was measured relative to a fixed local landscape feature visible in both images, and an average channel-migration rate was calculated at the point of maximum cutbank displacement. From these data it was determined that 65 percent of the measured sites have recently been migrating at a rate less than 1 ft/yr, 75 percent of the sites have been migrating at a rate less than 10 ft/yr, and while some sites are migrating in excess of 20 ft/yr, these occurrences are rare. In addition, it is shown that recent channel-migration activity is not evenly distributed across Indiana. For the stream reaches studied, far northern and much of far southern Indiana are drained by streams that recently have been relatively stationary. At the same time, this study shows that most of the largest streams in west-central Indiana and many of the largest streams in east-central Indiana have shown significant channel-migration activity during the recent past. It is anticipated that these results will support several fluvial-erosion-hazard mitigation activities currently being undertaken in Indiana.

  6. Quantifying the Availability of Vertebrate Hosts to Ticks: A Camera-Trapping Approach

    PubMed Central

    Hofmeester, Tim R.; Rowcliffe, J. Marcus; Jansen, Patrick A.

    2017-01-01

    The availability of vertebrate hosts is a major determinant of the occurrence of ticks and tick-borne zoonoses in natural and anthropogenic ecosystems and thus drives disease risk for wildlife, livestock, and humans. However, it remains challenging to quantify the availability of vertebrate hosts in field settings, particularly for medium-sized to large-bodied mammals. Here, we present a method that uses camera traps to quantify the availability of warm-bodied vertebrates to ticks. The approach is to deploy camera traps at questing height at a representative sample of random points across the study area, measure the average photographic capture rate for vertebrate species, and then correct these rates for the effective detection distance. The resulting “passage rate” is a standardized measure of the frequency at which vertebrates approach questing ticks, which we show is proportional to contact rate. A field test across twenty 1-ha forest plots in the Netherlands indicated that this method effectively captures differences in wildlife assemblage composition between sites. Also, the relative abundances of three life stages of the sheep tick Ixodes ricinus from drag sampling were correlated with passage rates of deer, which agrees with the known association with this group of host species, suggesting that passage rate effectively reflects the availability of medium- to large-sized hosts to ticks. This method will facilitate quantitative studies of the relationship between densities of questing ticks and the availability of different vertebrate species—wild as well as domesticated species—in natural and anthropogenic settings. PMID:28770219

  7. RENEW v3.2 user's manual, maintenance estimation simulation for Space Station Freedom Program

    NASA Technical Reports Server (NTRS)

    Bream, Bruce L.

    1993-01-01

    RENEW is a maintenance event estimation simulation program developed in support of the Space Station Freedom Program (SSFP). This simulation uses reliability and maintainability (R&M) and logistics data to estimate both average and time dependent maintenance demands. The simulation uses Monte Carlo techniques to generate failure and repair times as a function of the R&M and logistics parameters. The estimates are generated for a single type of orbital replacement unit (ORU). The simulation has been in use by the SSFP Work Package 4 prime contractor, Rocketdyne, since January 1991. The RENEW simulation gives closer estimates of performance since it uses a time dependent approach and depicts more factors affecting ORU failure and repair than steady state average calculations. RENEW gives both average and time dependent demand values. Graphs of failures over the mission period and yearly failure occurrences are generated. The averages demand rate for the ORU over the mission period is also calculated. While RENEW displays the results in graphs, the results are also available in a data file for further use by spreadsheets or other programs. The process of using RENEW starts with keyboard entry of the R&M and operational data. Once entered, the data may be saved in a data file for later retrieval. The parameters may be viewed and changed after entry using RENEW. The simulation program runs the number of Monte Carlo simulations requested by the operator. Plots and tables of the results can be viewed on the screen or sent to a printer. The results of the simulation are saved along with the input data. Help screens are provided with each menu and data entry screen.

  8. Temporal factors in motor-vehicle crash deaths: Ten years later.

    PubMed

    Weast, Rebecca

    2018-06-01

    To assess trends in traffic fatalities on several temporal scales: year to year, by month, by day of week, and by time of day, to determine why some times correspond with higher rates of crash deaths, and to assess how these trends relate to age, the role of the deceased, and alcohol consumption. Traffic fatalities were identified using the Fatality Analysis Reporting System (FARS) for 1998 through 2014 and assessed for their time of occurrence. Three days that, on average, contained particularly high numbers of crash deaths were then assessed in greater detail, considering the age of the deceased, role of the deceased (vehicle occupant, bicyclist, motorcyclist, or pedestrian), and the blood alcohol content of either the driver (for passenger vehicle occupants) or the deceased. Annual crash fatality totals were much lower in 2014 than in 1998, but the decrease was not steady; a marked drop in crash deaths occurred after 2007 and continued until 2014. On average the most fatalities per day occurred in July and August (116 per day), followed closely by June, September, and October. During the week, the greatest number of fatalities on average occur on weekend days, and during the day the most fatalities tend to occur between the hours of 3p.m. and 7p.m. Holidays like Independence Day and New Year's Day show elevated crash fatalities, and a greater percentage of these crashes involved alcohol, when compared with adjacent days. Certain days and times of year stand out as posing an elevated crash risk, and even with the decrease in average daily fatalities over the past decade, these days and times of year have remained consistent. These results indicate focused areas for continued efforts to reduce fatal crashes. Copyright © 2018 National Safety Council and Elsevier Ltd. All rights reserved.

  9. Angular measurement system

    NASA Technical Reports Server (NTRS)

    Currie, J. R.; Kissel, R. R.

    1986-01-01

    A system for the measurement of shaft angles is disclosed wherein a synchro resolver is sequentially pulsed, and alternately, a sine and then a cosine representative voltage output of it are sampled. Two like type, sine or cosine, succeeding outputs (V sub S1, V sub S2) are averaged and algebraically related to the opposite type output pulse (V sub c) occurring between the averaged pulses to provide a precise indication of the angle of a shaft coupled to the resolver at the instant of the occurrence of the intermediately occurring pulse (V sub c).

  10. [Anxiety disorders and influence factors in adolescent patients with cleft lip and palate].

    PubMed

    Liu, Chao; Ran, Hao; Jiang, Chang-wei; Zhou, Meng

    2015-10-01

    To investigate the anxiety disorders and influence factors that occur in adolescent patients with cleft lip and palate and to provide theoretical foundation for mental intervention. A total of 120 adolescent patients with cleft lip and palate were investigated using a general information questionnaire, the self-rating anxiety scale, and the social support rating scale (SSRS). The influence factors of anxiety disorders were analyzed. The effective questionnaires were 119. The occurrence rate of anxiety disorder in adolescent patients was 49.6% (59/119), and the occurrence rates of mild, moderate, and severe anxieties were 41.2% (49/119), 7.6% (9/119), and 0.8% (1/119), respectively. The gender, residential area, disease category, family status (one child or no children), and incidence rate of anxiety disorder in patients were statistically different (P<0.05). The SSRS scores of patients with anxiety disorder were lower than those of patients without anxiety disorder (P<0.05). Multiple regression analysis showed that gender and social support were predictive factors of the occurrence of anxiety disorder (R=0.318). A high anxiety disorder rate occurred in adolescent patients with cleft lip and palate. dender and social support were important influencing factors for anxiety disorder. In the after-mental intervention, considerable attention should be given to the anxiety disorders of patients and improve their mental health.

  11. Sediment-deposition rates and organic compounds in bottom sediment at four sites in Lake Mead, Nevada, May 1998

    USGS Publications Warehouse

    Covay, K.J.; Beck, D.A.

    2001-01-01

    In May 1998 the U.S. Geological Survey, in cooperation with the University of Nevada, Las Vegas, investigated rates of sediment deposition and concentrations of selected synthetic organic compounds at four sites in Lake Mead. Sediment cores were extracted from two sites (one shallow and one deep) in Las Vegas Bay, from one site in the Overton Arm, and from one site near the historic confluence of the Colorado and Virgin Rivers. The sediment cores were age-dated using cesium-137 and were analyzed for the presence of organochlorine compounds (pesticides and degradation products, polychlorinated biphenyls, dioxins, and furans) and for semivolatile organic compounds (polycyclic aromatic hydrocarbons and phenols). Sediment-deposition rates after impoundment of the Colorado River by Hoover Dam were determined by measuring the accumulation of mass during three different periods: (1) from the approximate impoundment date for each site (1935-37) to the initial occurrence of cesium-137 in the atmosphere (1952); (2) from 1952 to the maximum concentration of cesium-137 in the atmosphere (1964); and (3) from 1964 to the collection date of the sample (1998). Sediment-deposition rates for the entire post-impoundment period (1935-98) averaged 1.45 (g/cm2)/yr (grams per square centimeter per year) at the Las Vegas Bay shallow site, 1.25 (g/cm2)/yr at the Las Vegas Bay deep site, 0.80 (g/cm2)/yr at the Overton Arm site, and 0.65 (g/cm2)/yr at the Colorado and Virgin Rivers confluence site. Sediment-deposition rates after impoundment of the Colorado River by Hoover Dam were determined by measuring the accumulation of mass during three different periods: (1) from the approximate impoundment date for each site (1935-37) to the initial occurrence of cesium-137 in the atmosphere (1952); (2) from 1952 to the maximum concentration of cesium-137 in the atmosphere (1964); and (3) from 1964 to the collection date of the sample (1998). Sediment-deposition rates for the entire post-impoundment period (1935-98) averaged 1.45 (g/cm2)/yr (grams per square centimeter per year) at the Las Vegas Bay shallow site, 1.25 (g/cm2)/yr at the Las Vegas Bay deep site, 0.80 (g/cm2)/yr at the Overton Arm site, and 0.65 (g/cm2)/yr at the Colorado and Virgin Rivers confluence site. Total numbers of synthetic organic compounds detected in sediment samples were 48 at the Las Vegas Bay shallow site, 57 at the Las Vegas Bay deep site, 26 at the Overton Arm site, and 31 at the Colorado and Virgin Rivers confluence site. The most commonly detected organochlorine pesticide and polychlorinated biphenyl compounds were dichlorodiphenyldichloroethane and dichlorodiphenyldichloroethylene. The most commonly detected dioxin compounds were tetrachlorodibenzo-p-dioxin and octochlorodibenzo-p-dioxin. The most commonly detected furan compounds were tetrachlorodibenzofuran and octochlorodibenzofuran. The most commonly detected polycyclic aromatic hydrocarbons included perylene, benzo[g,h,i]perylene, 2,6-dimethylnaphthalene, and indeno[1,2,3-c,d]pyrene. The most commonly detected phenol compound was phenol.

  12. Landscape, demographic and climatic associations with human West Nile virus occurrence regionally in 2012 in the United States of America.

    PubMed

    DeGroote, John P; Sugumaran, Ramanathan; Ecker, Mark

    2014-11-01

    After several years of low West Nile virus (WNV) occurrence in the United States of America (USA), 2012 witnessed large outbreaks in several parts of the country. In order to understand the outbreak dynamics, spatial clustering and landscape, demographic and climatic associations with WNV occurrence were investigated at a regional level in the USA. Previous research has demonstrated that there are a handful of prominent WNV mosquito vectors with varying ecological requirements responsible for WNV transmission in the USA. Published range maps of these important vectors were georeferenced and used to define eight functional ecological regions in the coterminous USA. The number of human WNV cases and human populations by county were attained in order to calculate a WNV rate for each county in 2012. Additionally, a binary value (high/low) was calculated for each county based on whether the county WNV rate was above or below the rate for the region it fell in. Global Moran's I and Anselin Local Moran's I statistics of spatial association were used per region to examine and visualize clustering of the WNV rate and the high/low rating. Spatial data on landscape, demographic and climatic variables were compiled and derived from a variety of sources and then investigated in relation to human WNV using both Spearman rho correlation coefficients and Poisson regression models. Findings demonstrated significant spatial clustering of WNV and substantial inter-regional differences in relationships between WNV occurrence and landscape, demographic and climatically related variables. The regional associations were consistent with the ecologies of the dominant vectors for those regions. The large outbreak in the Southeast region was preceded by higher than normal winter and spring precipitation followed by dry and hot conditions in the summer.

  13. Temporal and Spatial Analysis of Neural Tube Defects and Detection of Geographical Factors in Shanxi Province, China

    PubMed Central

    He, Lei; Wang, Jinfeng; Liu, Xin; Zhang, Ningxu; Xu, Bing

    2016-01-01

    Background Neural tube defects (NTDs) are congenital birth defects that occur in the central nervous system, and they have the highest incidence among all birth defects. Shanxi Province in China has the world’s highest rate of NTDs. Since the 1990s, China’s government has worked on many birth defect prevention programs to reduce the occurrence of NTDs, such as pregnancy planning, health education, genetic counseling, antenatal ultrasonography and serological screening. However, the rate of NTDs in Shanxi Province is still higher than the world’s average morbidity rate after intervention. In addition, Shanxi Province has abundant coal reserves, and is the largest coal production province in China. The objectives of this study are to determine the temporal and spatial variation of the NTD rate in rural areas of Shanxi Province, China, and identify geographical environmental factors that were associated with NTDs in the risk area. Methods In this study, Heshun County and Yuanping County in Shanxi Province, which have high incidence of NTDs, were selected as the study areas. Two paired sample T test was used to analyze the changes in the risk of NTDs from the time dimension. Ripley’s k function and spatial filtering were combined with geographic information system (GIS) software to study the changes in the risk of NTDs from the spatial dimension. In addition, geographical detectors were used to identify the risk geographical environmental factors of NTDs in the study areas, especially the areas close to the coal sites and main roads. Results In both Heshun County and Yuanping County, the incidence of NTDs was significantly (P<0.05) reduced after intervention. The results from spatial analysis showed that significant spatial heterogeneity existed in both counties. NTD clusters were still identified in areas close to coal sites and main roads after interventions. This study also revealed that the elevation, fault and soil types always had a larger influence on the incidence of NTDs in our study areas. In addition, distance to the river was a risk factor of NTDs in areas close to the coal sites and main roads. Conclusion The existing interventions may have played an important role to reduce the incidence of NTDs. However, there is still spatial heterogeneity in both counties after using the traditional intervention methods. The government needs to take more measures to strengthen the environmental restoration to prevent the occurrence of NTDs, especially those areas close to coal sites and main roads. The outcome of this research provides an important theoretical basis and technical support for the government to prevent the occurrence of NTDs. PMID:27100082

  14. Exposure of Secondary School Adolescents from Argentina and Mexico to Smoking Scenes in Movies: a Population-based Estimation.

    PubMed

    Salgado, María V; Pérez, Adriana; Abad-Vivero, Erika N; Thrasher, James F; Sargent, James D; Mejía, Raúl

    2016-04-01

    Smoking scenes in movies promote adolescent smoking onset; thus, the analysis of the number of images of smoking in movies really reaching adolescents has become a subject of increasing interest. The aim of this study was to estimate the level of exposure to images of smoking in movies watched by adolescents in Argentina and Mexico. First-year secondary school students from Argentina and Mexico were surveyed. One hundred highest-grossing films from each year of the period 2009-2013 (Argentina) and 2010-2014 (Mexico) were analyzed. Each participant was assigned a random sample of 50 of these movies and was asked if he/she had watched them. The total number of adolescents who had watched each movie in each country was estimated and was multiplied by the number of smoking scenes (occurrences) in each movie to obtain the number of gross smoking impressions seen by secondary school adolescents from each country. Four-hundred and twenty-two movies were analyzed in Argentina and 433 in Mexico. Exposure to more than 500 million smoking impressions was estimated for adolescents in each country, averaging 128 and 121 minutes of smoking scenes seen by each Argentine and Mexican adolescent, respectively. Although 15, 16 and 18-rated movies had more smoking scenes in average, movies rated for younger teenagers were responsible for the highest number of smoking scenes watched by the students (67.3% in Argentina and 54.4% in Mexico) due to their larger audience. At the population level, movies aimed at children are responsible for the highest tobacco burden seen by adolescents.

  15. Integrating occurrence and detectability patterns based on interview data: a case study for threatened mammals in Equatorial Guinea

    USGS Publications Warehouse

    Martínez-Martí, Chele; Jiménez-Franco, María V.; Royle, J. Andrew; Palazón, José A.; Calvo, José F.

    2016-01-01

    Occurrence models that account for imperfect detection of species are increasingly used for estimating geographical range, for determining species-landscape relations and to prioritize conservation actions worldwide. In 2010, we conducted a large-scale survey in Río Muni, the mainland territory of Equatorial Guinea, which aimed to estimate the probabilities of occurrence and detection of threatened mammals based on environmental covariates, and to identify priority areas for conservation. Interviews with hunters were designed to record presence/absence data of seven species (golden cat, leopard, forest elephant, forest buffalo, western gorilla, chimpanzee and mandrill) in 225 sites throughout the region. We fitted single season occupancy models and recently developed models which also include false positive errors (i.e. species detected in places where it actually does not occur), which should provide more accurate estimates for most species, which are susceptible to mis-identification. Golden cat and leopard had the lowest occurrence rates in the region, whereas primates had the highest rates. All species, except gorilla, were affected negatively by human settlements. The southern half of Río Muni showed the highest occurrence of the species studied, and conservation strategies for ensuring the persistence of threatened mammals should be focused on this area.

  16. Integrating occurrence and detectability patterns based on interview data: a case study for threatened mammals in Equatorial Guinea.

    PubMed

    Martínez-Martí, Chele; Jiménez-Franco, María V; Royle, J Andrew; Palazón, José A; Calvo, José F

    2016-09-26

    Occurrence models that account for imperfect detection of species are increasingly used for estimating geographical range, for determining species-landscape relations and to prioritize conservation actions worldwide. In 2010, we conducted a large-scale survey in Río Muni, the mainland territory of Equatorial Guinea, which aimed to estimate the probabilities of occurrence and detection of threatened mammals based on environmental covariates, and to identify priority areas for conservation. Interviews with hunters were designed to record presence/absence data of seven species (golden cat, leopard, forest elephant, forest buffalo, western gorilla, chimpanzee and mandrill) in 225 sites throughout the region. We fitted single season occupancy models and recently developed models which also include false positive errors (i.e. species detected in places where it actually does not occur), which should provide more accurate estimates for most species, which are susceptible to mis-identification. Golden cat and leopard had the lowest occurrence rates in the region, whereas primates had the highest rates. All species, except gorilla, were affected negatively by human settlements. The southern half of Río Muni showed the highest occurrence of the species studied, and conservation strategies for ensuring the persistence of threatened mammals should be focused on this area.

  17. Integrating occurrence and detectability patterns based on interview data: a case study for threatened mammals in Equatorial Guinea

    PubMed Central

    Martínez-Martí, Chele; Jiménez-Franco, María V.; Royle, J. Andrew; Palazón, José A.; Calvo, José F.

    2016-01-01

    Occurrence models that account for imperfect detection of species are increasingly used for estimating geographical range, for determining species-landscape relations and to prioritize conservation actions worldwide. In 2010, we conducted a large-scale survey in Río Muni, the mainland territory of Equatorial Guinea, which aimed to estimate the probabilities of occurrence and detection of threatened mammals based on environmental covariates, and to identify priority areas for conservation. Interviews with hunters were designed to record presence/absence data of seven species (golden cat, leopard, forest elephant, forest buffalo, western gorilla, chimpanzee and mandrill) in 225 sites throughout the region. We fitted single season occupancy models and recently developed models which also include false positive errors (i.e. species detected in places where it actually does not occur), which should provide more accurate estimates for most species, which are susceptible to mis-identification. Golden cat and leopard had the lowest occurrence rates in the region, whereas primates had the highest rates. All species, except gorilla, were affected negatively by human settlements. The southern half of Río Muni showed the highest occurrence of the species studied, and conservation strategies for ensuring the persistence of threatened mammals should be focused on this area. PMID:27666671

  18. A Gridded Climatology of Clouds over Land (1971-1996) and Ocean (1954-2008) from Surface Observations Worldwide (NDP-026E)*

    DOE Data Explorer

    Hahn, C. J. [University of Arizona; Warren, S. G. [University of Washington

    2007-01-01

    Surface synoptic weather reports from ships and land stations worldwide were processed to produce a global cloud climatology which includes: total cloud cover, the amount and frequency of occurrence of nine cloud types within three levels of the troposphere, the frequency of occurrence of clear sky and of precipitation, the base heights of low clouds, and the non-overlapped amounts of middle and high clouds. Synoptic weather reports are made every three hours; the cloud information in a report is obtained visually by human observers. The reports used here cover the period 1971-96 for land and 1954-2008 for ocean. This digital archive provides multi-year monthly, seasonal, and annual averages in 5x5-degree grid boxes (or 10x10-degree boxes for some quantities over the ocean). Daytime and nighttime averages, as well as the diurnal average (average of day and night), are given. Nighttime averages were computed using only those reports that met an "illuminance criterion" (i.e., made under adequate moonlight or twilight), thus minimizing the "night-detection bias" and making possible the determination of diurnal cycles and nighttime trends for cloud types. The phase and amplitude of the first harmonic of both the diurnal cycle and the annual cycle are given for the various cloud types. Cloud averages for individual years are also given for the ocean for each of 4 seasons, and for each of the 12 months (daytime-only averages for the months). [Individual years for land are not gridded, but are given for individual stations in a companion data set, CDIAC's NDP-026D).] This analysis used 185 million reports from 5388 weather stations on continents and islands, and 50 million reports from ships; these reports passed a series of quality-control checks. This analysis updates (and in most ways supercedes) the previous cloud climatology constructed by the authors in the 1980s. Many of the long-term averages described here are mapped on the University of Washington, Department of Atmospheric Sciences Web site. The Online Cloud Atlas containing NDP-026E data is available via the University of Washington.

  19. Attributing Changing Rates of Temperature Record Breaking to Anthropogenic Influences

    NASA Astrophysics Data System (ADS)

    King, Andrew D.

    2017-11-01

    Record-breaking temperatures attract attention from the media, so understanding how and why the rate of record breaking is changing may be useful in communicating the effects of climate change. A simple methodology designed for estimating the anthropogenic influence on rates of record breaking in a given time series is proposed here. The frequency of hot and cold record-breaking temperature occurrences is shown to be changing due to the anthropogenic influence on the climate. Using ensembles of model simulations with and without human-induced forcings, it is demonstrated that the effect of climate change on global record-breaking temperatures can be detected as far back as the 1930s. On local scales, a climate change signal is detected more recently at most locations. The anthropogenic influence on the increased occurrence of hot record-breaking temperatures is clearer than it is for the decreased occurrence of cold records. The approach proposed here could be applied in rapid attribution studies of record extremes to quantify the influence of climate change on the rate of record breaking in addition to the climate anomaly being studied. This application is demonstrated for the global temperature record of 2016 and the Central England temperature record in 2014.

  20. Submarine groundwater discharge in the Sarasota Bay system: Its assessment and implications for the nearshore coastal environment

    NASA Astrophysics Data System (ADS)

    Mwashote, B. M.; Murray, M.; Burnett, W. C.; Chanton, J.; Kruse, S.; Forde, A.

    2013-02-01

    A study was conducted from July 2002 through June 2006 in order to assess the significance of submarine groundwater discharge (SGD) to Sarasota Bay (SB), Florida. The assessment approaches used in this study included manual seepage meters, geochemical tracers (radon, 222Rn and methane, CH4), and subseafloor resistivity measurements. The estimated SGD advection rates in the SB system were found to range from 0.7 to 24.0 cm/day, except for some isolated hot spot occurrences where higher rates were observed. In general, SGD estimates were relatively higher (5.9-24.0 cm/day) in the middle and south regions of the bay compared to the north region (0.7-5.9 cm/day). Average dissolved inorganic nutrient concentrations within the SB water column ranged: 0.1-11 μM (NO2+NO3), 0.1-9.1 μM (NH4) and 0.2-1.4 μM (PO4). The average N/P ratio was higher in the north compared to the middle and south regions of the bay. On average, we conservatively estimate that about 27% of the total N in the SB system was derived via SGD. The prevalence of shallow embayed areas in the SB system and the presence of numerous septic tanks in the surrounding settlements enhanced the potential effects of nutrient rich seepages. Statistical comparison of the quantitative approaches revealed a good agreement between SGD estimates from manual seepage meters and those derived from the 222Rn model (p=0.67; α=0.05; n=18). CH4 was found to be useful for qualitative SGD assessments. CH4 and 222Rn were correlated (r2=0.31; α=0.05; n=54). Large scale resistivity surveys showed spatial variability that correlates more clearly with lithology than with SGD patterns.

  1. Pain and Injury Associated with Powerlifting Training in Visually Impaired Athletes.

    ERIC Educational Resources Information Center

    Haykowsky, Mark J.; Warburton, Darren E. R.

    1999-01-01

    This study assessed occurrence and level of pain and injury history associated with powerlifting training in 11 adults with visual impairments. Powerlifting training was associated with an elevated occurrence of pain in shoulders, elbows, lower back, and knee regions. Injury rate, however, was lower than for athletes without visual impairments.…

  2. [Social capital, violent deaths, and cancer mortality in Colombia: a population approach].

    PubMed

    Idrovo, Alvaro Javier

    2006-01-01

    In Colombia there are evidences that social capital (SC) is associated with greater rates of violent crime ("perverse" SC). This study explores the relation between SC, violent deaths (1973-1996), and the accumulated occurrence of cancer deaths (1990-1996). An ecologic study with the 33 Colombian departments was carried out. Correlations between violent deaths (inverse proxy of SC), the internal displacement ratio, and the mortality rates by each type of cancer. With robust regressions the effect of violent deaths ("perverse" SC) on the occurrence of mortality cancer were explored, adjusting by economic convergence or polarization (1960-1995), and the internal displacement ratio until 1996. Positive correlations (p < 0.05) between violent deaths ("perverse "CS) and all types of cancer, except breast and lung among men, were observed. In all the cases statistically significant associations were observed, after adjust by departments' economic convergence/polarization and internal displacement. This study shows a direct relation between violent deaths on the occurrence of cancer. The findings obtained here suggest an inverted U shape relation between SC and disease occurrence.

  3. Credible occurrence probabilities for extreme geophysical events: earthquakes, volcanic eruptions, magnetic storms

    USGS Publications Warehouse

    Love, Jeffrey J.

    2012-01-01

    Statistical analysis is made of rare, extreme geophysical events recorded in historical data -- counting the number of events $k$ with sizes that exceed chosen thresholds during specific durations of time $\\tau$. Under transformations that stabilize data and model-parameter variances, the most likely Poisson-event occurrence rate, $k/\\tau$, applies for frequentist inference and, also, for Bayesian inference with a Jeffreys prior that ensures posterior invariance under changes of variables. Frequentist confidence intervals and Bayesian (Jeffreys) credibility intervals are approximately the same and easy to calculate: $(1/\\tau)[(\\sqrt{k} - z/2)^{2},(\\sqrt{k} + z/2)^{2}]$, where $z$ is a parameter that specifies the width, $z=1$ ($z=2$) corresponding to $1\\sigma$, $68.3\\%$ ($2\\sigma$, $95.4\\%$). If only a few events have been observed, as is usually the case for extreme events, then these "error-bar" intervals might be considered to be relatively wide. From historical records, we estimate most likely long-term occurrence rates, 10-yr occurrence probabilities, and intervals of frequentist confidence and Bayesian credibility for large earthquakes, explosive volcanic eruptions, and magnetic storms.

  4. Occurrence of infectious laryngotracheitis outbreaks in commercial layer hens detected by ELISA.

    PubMed

    Aras, Zeki; Yavuz, Orhan; Sanioğlu Gölen, Gökçenur

    2018-02-09

    Infectious laryngotracheitis (ILT) is an acute respiratory disease of chickens and a cause of great economic loss in commercial layers. The aims of this study were to investigate the prevalence of ILT in the field outbreaks and to compare the characteristics of ILT-infected and free flocks of commercial layers. A total of 625 blood serum samples were collected from 25 different layer flocks. The presence of antibodies against infectious laryngotracheitis virus (ILTV) in each sample was determined by ELISA. Of the 625 serum samples, 266 (42.56%) were found to be positive for ILTV antibodies. A total of 16 (64%) flocks were detected ILT positive by ELISA method. The mortality of infected flocks was statistically higher (P < 0.05) than uninfected flocks. The egg production of positive flocks was lower than that of the free flocks, but this difference was not statistically significant. The average live weight of hens in infected flocks was lower (P > 0.05) than hens in free flocks. In conclusion, the results of this study indicated a high prevalence of ILT infection in the commercial layer flocks in Konya region, Turkey. In outbreaks, ILT significantly increased the mortality rate and decreased the average live weight in layer hens.

  5. Spread-F occurrences and relationships with foF2 and h'F at low- and mid-latitudes in China

    NASA Astrophysics Data System (ADS)

    Wang, Ning; Guo, Lixin; Zhao, Zhenwei; Ding, Zonghua; Lin, Leke

    2018-04-01

    Ionospheric irregularities are an important phenomenon in scientific studies and applications of radio-wave propagation. Spread-F echoes in ionograms are a type of high-frequency band irregularities that include frequency spread-F (FSF), range spread-F (RSF), and mixed spread-F (MSF) events. In this study, we obtained spread-F data from four ionosondes at low- and mid-latitudes near the 120°E chain in China during the 23rd solar cycle. We used these data to investigate spread-F occurrence percentages and variations with local time, season, latitude, and solar activity. The four ionosondes were located at Haikou (HK) (20°N, 110.34°E), Guangzhou (GZ) (23.14°N, 113.36°E), Beijing (BJ) (40.11°N, 116.28°E), and Changchun (CC) (43.84°N, 125.28°E). We also present possible correlations between spread-Fs and other ionospheric parameters, such as the critical frequency of the F2-layer (foF2) and the virtual height of the bottom-side F-layer (h'F). In particular, we investigated the possible threshold of the foF2 affecting the FSF and the relationship between the h'F and the RSF. The main conclusions are as follows: (a) the FSF occurrence percentages were anti-correlated with solar activity at all four sites; meanwhile, RSF occurrence rates increased with the increase in solar activity at HK, but not at the other three sites; (b) FSF occurrence rates were larger at the mid-latitudes than expected, while FSFs occurred more often after midnight; (c) the highest FSF occurrence rates mostly appeared during the summer months, while RSFs occurred mostly in the equinoctial months of 2000-2002 at HK and GZ; (d) a lower foF2 was suitable for FSF events; nevertheless, h'F and RSF occurrences satisfied the parabolic relationship; (e) the foF2 thresholds for FSFs were 15, 14, 7.6, and 7.8 MHz at HK, GZ, BJ, and CC, respectively. The h'Fs occurring between 240 and 290 km were more favorable for RSF occurrences. These results are important for understanding ionospheric irregularity variations in eastern Asia and for improving space weather modeling and forecasting capabilities[Figure not available: see fulltext.] .

  6. Scrap tyre pyrolysis: Modified chemical percolation devolatilization (M-CPD) to describe the influence of pyrolysis conditions on product yields.

    PubMed

    Tan, Vincent; De Girolamo, Anthony; Hosseini, Tahereh; Alhesan, Jameel Aljariri; Zhang, Lian

    2018-03-16

    This paper attempts to develop a modified chemical percolation devolatilization (M-CPD) model that can include heat transfer, primary pyrolysis and the secondary cracking reactions of volatiles together to describe the pyrolysis of waste scrap tyre chip, as well as to examine the influence of operating conditions on the scrap tyre pyrolysis product yields. Such a study has yet to be conducted in the past, thereby leading to a large knowledge gap failing to understand the pyrolysis of the coarse feedstock appropriately. To validate the developed model, a number of operating parameters including reactor configurations, carrier gas compositions (argon and argon blended with CO 2 and/or steam), scrap tyre chip size (0.5-15.0 mm), terminal pyrolysis temperature (400-800 °C) and heating rate (10 °C/min and 110 °C/min) were examined in a lab-scale fixed-bed pyrolyser, with a particular focus on the secondary cracking extents of the liquid tar. Through both experimental investigation and modelling approach, it was found that significant secondary cracking extent occurred upon the increase in the feedstock size, heating rate and residence time. Upon the fast pyrolysis, the average temperature gap between the centres of the coarse particle and reactor wall could reach a maximum of 115 °C for the tyre chips of 6-15 mm. Consequently, its primary volatiles underwent the secondary cracking reaction at an overall extent of 17% at a terminal temperature of 600 °C and a fast heating rate of 110 °C/min. Consequently, the yield of light gases including methane was increased remarkably. The flow rate of inert carrier gas was also influential in the secondary cracking, in which a maximum tar yield (54 wt%) was reached at a carrier gas flow rate of 1.5  L/min. This indicates the occurrence of secondary cracking has been largely minimised. At a pyrolysis temperature of 600 °C, the addition of CO 2 in the carrier gas had an insignificant effect on the product yield distribution under the slow heating scheme. In contrast, the addition of steam resulted in a slight increase of carbon monoxide, presumably due to the occurrence of gasification reaction. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Genome size analyses of Pucciniales reveal the largest fungal genomes.

    PubMed

    Tavares, Sílvia; Ramos, Ana Paula; Pires, Ana Sofia; Azinheira, Helena G; Caldeirinha, Patrícia; Link, Tobias; Abranches, Rita; Silva, Maria do Céu; Voegele, Ralf T; Loureiro, João; Talhinhas, Pedro

    2014-01-01

    Rust fungi (Basidiomycota, Pucciniales) are biotrophic plant pathogens which exhibit diverse complexities in their life cycles and host ranges. The completion of genome sequencing of a few rust fungi has revealed the occurrence of large genomes. Sequencing efforts for other rust fungi have been hampered by uncertainty concerning their genome sizes. Flow cytometry was recently applied to estimate the genome size of a few rust fungi, and confirmed the occurrence of large genomes in this order (averaging 225.3 Mbp, while the average for Basidiomycota was 49.9 Mbp and was 37.7 Mbp for all fungi). In this work, we have used an innovative and simple approach to simultaneously isolate nuclei from the rust and its host plant in order to estimate the genome size of 30 rust species by flow cytometry. Genome sizes varied over 10-fold, from 70 to 893 Mbp, with an average genome size value of 380.2 Mbp. Compared to the genome sizes of over 1800 fungi, Gymnosporangium confusum possesses the largest fungal genome ever reported (893.2 Mbp). Moreover, even the smallest rust genome determined in this study is larger than the vast majority of fungal genomes (94%). The average genome size of the Pucciniales is now of 305.5 Mbp, while the average Basidiomycota genome size has shifted to 70.4 Mbp and the average for all fungi reached 44.2 Mbp. Despite the fact that no correlation could be drawn between the genome sizes, the phylogenomics or the life cycle of rust fungi, it is interesting to note that rusts with Fabaceae hosts present genomes clearly larger than those with Poaceae hosts. Although this study comprises only a small fraction of the more than 7000 rust species described, it seems already evident that the Pucciniales represent a group where genome size expansion could be a common characteristic. This is in sharp contrast to sister taxa, placing this order in a relevant position in fungal genomics research.

  8. Genome size analyses of Pucciniales reveal the largest fungal genomes

    PubMed Central

    Tavares, Sílvia; Ramos, Ana Paula; Pires, Ana Sofia; Azinheira, Helena G.; Caldeirinha, Patrícia; Link, Tobias; Abranches, Rita; Silva, Maria do Céu; Voegele, Ralf T.; Loureiro, João; Talhinhas, Pedro

    2014-01-01

    Rust fungi (Basidiomycota, Pucciniales) are biotrophic plant pathogens which exhibit diverse complexities in their life cycles and host ranges. The completion of genome sequencing of a few rust fungi has revealed the occurrence of large genomes. Sequencing efforts for other rust fungi have been hampered by uncertainty concerning their genome sizes. Flow cytometry was recently applied to estimate the genome size of a few rust fungi, and confirmed the occurrence of large genomes in this order (averaging 225.3 Mbp, while the average for Basidiomycota was 49.9 Mbp and was 37.7 Mbp for all fungi). In this work, we have used an innovative and simple approach to simultaneously isolate nuclei from the rust and its host plant in order to estimate the genome size of 30 rust species by flow cytometry. Genome sizes varied over 10-fold, from 70 to 893 Mbp, with an average genome size value of 380.2 Mbp. Compared to the genome sizes of over 1800 fungi, Gymnosporangium confusum possesses the largest fungal genome ever reported (893.2 Mbp). Moreover, even the smallest rust genome determined in this study is larger than the vast majority of fungal genomes (94%). The average genome size of the Pucciniales is now of 305.5 Mbp, while the average Basidiomycota genome size has shifted to 70.4 Mbp and the average for all fungi reached 44.2 Mbp. Despite the fact that no correlation could be drawn between the genome sizes, the phylogenomics or the life cycle of rust fungi, it is interesting to note that rusts with Fabaceae hosts present genomes clearly larger than those with Poaceae hosts. Although this study comprises only a small fraction of the more than 7000 rust species described, it seems already evident that the Pucciniales represent a group where genome size expansion could be a common characteristic. This is in sharp contrast to sister taxa, placing this order in a relevant position in fungal genomics research. PMID:25206357

  9. Occurrence of graft-versus-host disease increases mortality after umbilical cord blood transplantation for acute myeloid leukaemia: a report from Eurocord and the ALWP of the EBMT.

    PubMed

    Baron, F; Ruggeri, A; Beohou, E; Labopin, M; Mohty, M; Sanz, J; Vigouroux, S; Furst, S; Bosi, A; Chevallier, P; Cornelissen, J J; Michallet, M; Sierra, J; Karakasis, D; Savani, B N; Gluckman, E; Nagler, A

    2018-02-01

    The efficacy of umbilical cord blood transplantation (UCBT) as treatment for acute myeloid leukaemia (AML) relies on immune-mediated graft-versus-leukaemia effects. Previous studies have suggested a strong association between graft-versus-host disease (GVHD) occurrence and graft-versus-leukaemia effects after allogeneic hematopoietic cell transplantation. Here, we evaluated the kinetics of relapse rate in correlation with GVHD occurrence after UCBT. The kinetics of relapse rate over time in correlation to GVHD occurrence were assessed by calculating the relapse rate per patient-year within sequential 90-day intervals. The impact of GVHD on relapse and mortality was further studied in multivariate Cox models handling GVHD as a time-dependent covariate. The study included data from 1068 patients given single (n = 567) or double (n = 501) UCBT. The proportion of patients with grade II, III and IV acute GVHD was 20%, 7% and 4%, respectively. At 2 years, the cumulative incidence of chronic GVHD was 42%, the cumulative incidence of relapse was 32%, and overall survival was 32% as well. Relapse rates declined gradually over time during the first 30 months after transplantation. There was a possible suggestion that grade II-IV acute (HR = 0.8, P = 0.1) and chronic (HR = 0.65, P = 0.1) GVHD decreased relapse risk. However, grade II-IV acute GVHD significantly increased early (the first 18 months after UCBT) mortality (HR = 1.3, P = 0.02), whilst chronic GVHD increased each early (HR = 2.7, P < 0.001) and late (HR = 4.9, P < 0.001) mortality after UCBT. The occurrence of grade II-IV acute or chronic GVHD each increases overall mortality after UCBT for AML mitigating the possible graft-versus-leukemia effect of GVHD. © 2017 The Association for the Publication of the Journal of Internal Medicine.

  10. Modelling the effects of environmental conditions on the acoustic occurrence and behaviour of Antarctic blue whales

    PubMed Central

    Shabangu, Fannie W.; Yemane, Dawit; Stafford, Kathleen M.; Ensor, Paul; Findlay, Ken P.

    2017-01-01

    Harvested to perilously low numbers by commercial whaling during the past century, the large scale response of Antarctic blue whales Balaenoptera musculus intermedia to environmental variability is poorly understood. This study uses acoustic data collected from 586 sonobuoys deployed in the austral summers of 1997 through 2009, south of 38°S, coupled with visual observations of blue whales during the IWC SOWER line-transect surveys. The characteristic Z-call and D-call of Antarctic blue whales were detected using an automated detection template and visual verification method. Using a random forest model, we showed the environmental preferences pattern, spatial occurrence and acoustic behaviour of Antarctic blue whales. Distance to the southern boundary of the Antarctic Circumpolar Current (SBACC), latitude and distance from the nearest Antarctic shores were the main geographic predictors of blue whale call occurrence. Satellite-derived sea surface height, sea surface temperature, and productivity (chlorophyll-a) were the most important environmental predictors of blue whale call occurrence. Call rates of D-calls were strongly predicted by the location of the SBACC, latitude and visually detected number of whales in an area while call rates of Z-call were predicted by the SBACC, latitude and longitude. Satellite-derived sea surface height, wind stress, wind direction, water depth, sea surface temperatures, chlorophyll-a and wind speed were important environmental predictors of blue whale call rates in the Southern Ocean. Blue whale call occurrence and call rates varied significantly in response to inter-annual and long term variability of those environmental predictors. Our results identify the response of Antarctic blue whales to inter-annual variability in environmental conditions and highlighted potential suitable habitats for this population. Such emerging knowledge about the acoustic behaviour, environmental and habitat preferences of Antarctic blue whales is important in improving the management and conservation of this highly depleted species. PMID:28222124

  11. Modelling the effects of environmental conditions on the acoustic occurrence and behaviour of Antarctic blue whales.

    PubMed

    Shabangu, Fannie W; Yemane, Dawit; Stafford, Kathleen M; Ensor, Paul; Findlay, Ken P

    2017-01-01

    Harvested to perilously low numbers by commercial whaling during the past century, the large scale response of Antarctic blue whales Balaenoptera musculus intermedia to environmental variability is poorly understood. This study uses acoustic data collected from 586 sonobuoys deployed in the austral summers of 1997 through 2009, south of 38°S, coupled with visual observations of blue whales during the IWC SOWER line-transect surveys. The characteristic Z-call and D-call of Antarctic blue whales were detected using an automated detection template and visual verification method. Using a random forest model, we showed the environmental preferences pattern, spatial occurrence and acoustic behaviour of Antarctic blue whales. Distance to the southern boundary of the Antarctic Circumpolar Current (SBACC), latitude and distance from the nearest Antarctic shores were the main geographic predictors of blue whale call occurrence. Satellite-derived sea surface height, sea surface temperature, and productivity (chlorophyll-a) were the most important environmental predictors of blue whale call occurrence. Call rates of D-calls were strongly predicted by the location of the SBACC, latitude and visually detected number of whales in an area while call rates of Z-call were predicted by the SBACC, latitude and longitude. Satellite-derived sea surface height, wind stress, wind direction, water depth, sea surface temperatures, chlorophyll-a and wind speed were important environmental predictors of blue whale call rates in the Southern Ocean. Blue whale call occurrence and call rates varied significantly in response to inter-annual and long term variability of those environmental predictors. Our results identify the response of Antarctic blue whales to inter-annual variability in environmental conditions and highlighted potential suitable habitats for this population. Such emerging knowledge about the acoustic behaviour, environmental and habitat preferences of Antarctic blue whales is important in improving the management and conservation of this highly depleted species.

  12. First Study on the Occurrence Frequency of Equatorial Plasma Bubbles over West Africa Using an All-Sky Airglow Imager and GNSS Receivers

    NASA Astrophysics Data System (ADS)

    Okoh, Daniel; Rabiu, Babatunde; Shiokawa, Kazuo; Otsuka, Yuichi; Segun, Bolaji; Falayi, Elijah; Onwuneme, Sylvester; Kaka, Rafiat

    2017-12-01

    This is the first paper that reports the occurrence frequency of equatorial plasma bubbles and their dependences of local time, season, and geomagnetic activity based on airglow imaging observations at West Africa. The all-sky imager, situated in Abuja (Geographic: 8.99°N, 7.38°E; Geomagnetic: 1.60°S), has a 180° fisheye view covering almost the entire airspace of Nigeria. Plasma bubbles are observed for 70 nights of the 147 clear-sky nights from 9 June 2015 to 31 January 2017. Differences between nighttime and daytime ROTIs were also computed as a proxy of plasma bubbles using Global Navigation Satellite Systems (GNSS) receivers within the coverage of the all-sky imager. Most plasma bubble occurrences are found during equinoxes and least occurrences during solstices. The occurrence rate of plasma bubbles was highest around local midnight and lower for hours farther away. Most of the postmidnight plasma bubbles were observed around the months of December to March, a period that coincides with the harmattan period in Nigeria. The on/off status of plasma bubble in airglow and GNSS observations were in agreement for 67.2% of the total 768 h, while we suggest several reasons responsible for the remaining 32.8% when the airglow and GNSS bubble status are inconsistent. A majority of the plasma bubbles were observed under relatively quiet geomagnetic conditions (Dst ≥ -40 and Kp ≤ 3), but there was no significant pattern observed in the occurrence rate of plasma bubbles as a function of geomagnetic activity. We suggest that geomagnetic activities could have either suppressed or promoted the occurrence of plasma bubbles.

  13. Rate and Risk of Anterior Cruciate Ligament Injury Among Sportswomen in Slovenia

    PubMed Central

    Vauhnik, Renata; Morrissey, Matthew C.; Rutherford, Olga M.; Turk, Zmago; Pilih, Iztok A.; Perme, Maja Pohar

    2011-01-01

    Abstract Context: Anterior cruciate ligament (ACL)-injury rate is greater among female athletes than among male athletes. Objective: To investigate the rate and risk of ACL injury among Slovenian sportswomen playing professional basketball, team handball, or volleyball. Design: Prospective cohort study. Setting: The Slovenian National Organizations of basketball, team handball, and volleyball. Patients or Other Participants: During the 2003–2004 season, we prospectively followed 585 Slovenian sportswomen registered in the Slovenian National Organizations of basketball, team handball, and volleyball. Main Outcome Measure(s): We asked sportswomen and coaches to document the occurrence of every significant traumatic knee injury requiring medical attention. Injury rate and injury risk were calculated for sportswomen in each sport group. To calculate injury rate, we estimated the average exposure of each sportswoman during the research period. Results: During the 2003–2004 season, 585 Slovenian sportswomen sustained 12 ACL injuries. The ACL-injury risk was different in athletes participating in the various sports, with basketball players having the greatest ACL-injury risk and volleyball players having the lowest ACL-injury risk (P  =  .04). The risk of ACL injury among Slovenian sportswomen was 2.1 per 100 athletes (95% confidence interval  =  0.9, 3.2), whereas the rate of ACL injury was 0.037 per 1000 exposure hours (95% confidence interval  =  0.016, 0.06). Conclusions: Overall differences in injury risk were found among sports, but no differences were noted among divisions within sports. No differences for injury rate were observed between or within sports. The rate and risk of ACL injury among Slovenian sportswomen are high, with basketball players having the greatest ACL-injury risk. PMID:21214356

  14. Statistical characteristics of locally generated ESF during equinoctial months over Sanya

    NASA Astrophysics Data System (ADS)

    Meng, Xing; Fang, Hanxian; Li, Guozhu; Weng, Libin

    2018-05-01

    Understanding the local generation rate of equatorial spread-F (ESF) is important for forecasting ionospheric scintillation. Using the GPS ionospheric scintillation/TEC and VHF radar data during March-April and September-October from 2010 to 2014, the occurrence of ionospheric scintillation, TEC fast fluctuation, and backscatter plume were studied. Through analyzing the simultaneous occurrence of ionospheric scintillation, TEC fast fluctuation and backscatter plume, the local generation rate of ESF over Sanya was investigated. The results show that the monthly generation rate varies between 0% and 68%. A significant equinoctial asymmetry of local generation rate of ESF can be found in 2010, 2013 and 2014. The local generation rate of ESF increases from 2010 to 2014 during March-April, while it does not have similar trend during September-October. The plasma vertical drift influenced by solar activity has a significant impact on the monthly generation rate. The equinoctial asymmetry of plasma vertical drift may contribute a lot to the equinoctial asymmetry of the generation rate of ESF.

  15. Probabilistic model for quick detection of dissimilar binary images

    NASA Astrophysics Data System (ADS)

    Mustafa, Adnan A. Y.

    2015-09-01

    We present a quick method to detect dissimilar binary images. The method is based on a "probabilistic matching model" for image matching. The matching model is used to predict the probability of occurrence of distinct-dissimilar image pairs (completely different images) when matching one image to another. Based on this model, distinct-dissimilar images can be detected by matching only a few points between two images with high confidence, namely 11 points for a 99.9% successful detection rate. For image pairs that are dissimilar but not distinct-dissimilar, more points need to be mapped. The number of points required to attain a certain successful detection rate or confidence depends on the amount of similarity between the compared images. As this similarity increases, more points are required. For example, images that differ by 1% can be detected by mapping fewer than 70 points on average. More importantly, the model is image size invariant; so, images of any sizes will produce high confidence levels with a limited number of matched points. As a result, this method does not suffer from the image size handicap that impedes current methods. We report on extensive tests conducted on real images of different sizes.

  16. Expansion rate and geometry of floating vegetation mats on the margins of thermokarst lakes, northern Seward Peninsula, Alaska, USA

    USGS Publications Warehouse

    Parsekian, A.D.; Jones, Benjamin M.; Jones, M.; Grosse, G.; Walter, Anthony K.M.; Slater, L.

    2011-01-01

    Investigations on the northern Seward Peninsula in Alaska identified zones of recent (<50years) permafrost collapse that led to the formation of floating vegetation mats along thermokarst lake margins. The occurrence of floating vegetation mat features indicates rapid degradation of near-surface permafrost and lake expansion. This paper reports on the recent expansion of these collapse features and their geometry is determined using geophysical and remote sensing measurements. The vegetation mats were observed to have an average thickness of 0.57m and petrophysical modeling indicated that gas content of 1.5-5% enabled floatation above the lake surface. Furthermore, geophysical investigation provides evidence that the mats form by thaw and subsidence of the underlying permafrost rather than terrestrialization. The temperature of the water below a vegetation mat was observed to remain above freezing late in the winter. Analysis of satellite and aerial imagery indicates that these features have expanded at maximum rates of 1-2myr-1 over a 56year period. Including the spatial coverage of floating 'thermokarst mats' increases estimates of lake area by as much as 4% in some lakes. ?? 2011 John Wiley & Sons, Ltd.

  17. Exploring exoplanet populations with NASA’s Kepler Mission

    PubMed Central

    Batalha, Natalie M.

    2014-01-01

    The Kepler Mission is exploring the diversity of planets and planetary systems. Its legacy will be a catalog of discoveries sufficient for computing planet occurrence rates as a function of size, orbital period, star type, and insolation flux. The mission has made significant progress toward achieving that goal. Over 3,500 transiting exoplanets have been identified from the analysis of the first 3 y of data, 100 planets of which are in the habitable zone. The catalog has a high reliability rate (85–90% averaged over the period/radius plane), which is improving as follow-up observations continue. Dynamical (e.g., velocimetry and transit timing) and statistical methods have confirmed and characterized hundreds of planets over a large range of sizes and compositions for both single- and multiple-star systems. Population studies suggest that planets abound in our galaxy and that small planets are particularly frequent. Here, I report on the progress Kepler has made measuring the prevalence of exoplanets orbiting within one astronomical unit of their host stars in support of the National Aeronautics and Space Administration’s long-term goal of finding habitable environments beyond the solar system. PMID:25049406

  18. Using satellite-based measurements to explore ...

    EPA Pesticide Factsheets

    New particle formation (NPF) can potentially alter regional climate by increasing aerosol particle (hereafter particle) number concentrations and ultimately cloud condensation nuclei. The large scales on which NPF is manifest indicate potential to use satellite-based (inherently spatially averaged) measurements of atmospheric conditions to diagnose the occurrence of NPF and NPF characteristics. We demonstrate the potential for using satellite-measurements of insolation (UV), trace gas concentrations (sulfur dioxide (SO2), nitrogen dioxide (NO2), ammonia (NH3), formaldehyde (HCHO), ozone (O3)), aerosol optical properties (aerosol optical depth (AOD), Ångström exponent (AE)), and a proxy of biogenic volatile organic compound emissions (leaf area index (LAI), temperature (T)) as predictors for NPF characteristics: formation rates, growth rates, survival probabilities, and ultrafine particle (UFP) concentrations at five locations across North America. NPF at all sites is most frequent in spring, exhibits a one-day autocorrelation, and is associated with low condensational sink (AOD×AE) and HCHO concentrations, and high UV. However, there are important site-to-site variations in NPF frequency and characteristics, and in which of the predictor variables (particularly gas concentrations) significantly contribute to the explanatory power of regression models built to predict those characteristics. This finding may provide a partial explanation for the reported spatia

  19. Evaluation of a buried vertical well leachate recirculation system for municipal solid waste landfills.

    PubMed

    Kadambala, Ravi; Powell, Jon; Singh, Karamjit; Townsend, Timothy G

    2016-12-01

    Vertical liquids addition systems have been used at municipal landfills as a leachate management method and to enhance biostabilization of waste. Drawbacks of these systems include a limitation on pressurized injection and the occurrence of seepage. A novel vertical well system that employed buried wells constructed below a lift of compacted waste was operated for 153 days at a landfill in Florida, USA. The system included 54 wells installed in six clusters of nine wells connected with a horizontally-oriented manifold system. A cumulative volume of 8430 m 3 of leachate was added intermittently into the well clusters over the duration of the project with no incidence of surface seeps. Achievable average flow rates ranged from 9.3 × 10 -4 m 3 s -1 to 14.2 × 10 -4 m 3 s -1 , which was similar to or greater than flow rates achieved in a previous study using traditional vertical wells at the same landfill site. The results demonstrated that pressurized liquids addition in vertical wells at municipal solid waste landfills can be achieved while avoiding typical operational and maintenance issues associated with seeps. © The Author(s) 2016.

  20. Kinematic and Microphysical Significance of Lightning Jumps versus Non-Jump Increases in Total Flash Rate

    PubMed Central

    Schultz, Christopher J.; Carey, Lawrence D.; Schultz, Elise V.; Blakeslee, Richard J.

    2017-01-01

    Thirty-nine thunderstorms are examined using multiple-Doppler, polarimetric and total lightning observations to understand the role of mixed phase kinematics and microphysics in the development of lightning jumps. This sample size is larger than those of previous studies on this topic. The principal result of this study is that lightning jumps are a result of mixed phase updraft intensification. Larger increases in intense updraft volume (≥ 10 m s−1) and larger changes in peak updraft speed are observed prior to lightning jump occurrence when compared to other non-jump increases in total flash rate. Wilcoxon-Mann-Whitney Rank Sum testing yields p-values ≤0.05, indicating statistical independence between lightning jump and non-jump distributions for these two parameters. Similar changes in mixed phase graupel mass magnitude are observed prior to lightning jumps and non-jump increases in total flash rate. The p-value for graupel mass change is p=0.096, so jump and non-jump distributions for graupel mass change are not found statistically independent using the p=0.05 significance level. Timing of updraft volume, speed and graupel mass increases are found to be 4 to 13 minutes in advance of lightning jump occurrence. Also, severe storms without lightning jumps lack robust mixed phase updrafts, demonstrating that mixed phase updrafts are not always a requirement for severe weather occurrence. Therefore, the results of this study show that lightning jump occurrences are coincident with larger increases in intense mixed phase updraft volume and peak updraft speed than smaller non-jump increases in total flash rate. PMID:29158622

  1. Kinematic and Microphysical Significance of Lightning Jumps versus Non-Jump Increases in Total Flash Rate.

    PubMed

    Schultz, Christopher J; Carey, Lawrence D; Schultz, Elise V; Blakeslee, Richard J

    2017-02-01

    Thirty-nine thunderstorms are examined using multiple-Doppler, polarimetric and total lightning observations to understand the role of mixed phase kinematics and microphysics in the development of lightning jumps. This sample size is larger than those of previous studies on this topic. The principal result of this study is that lightning jumps are a result of mixed phase updraft intensification. Larger increases in intense updraft volume (≥ 10 m s -1 ) and larger changes in peak updraft speed are observed prior to lightning jump occurrence when compared to other non-jump increases in total flash rate. Wilcoxon-Mann-Whitney Rank Sum testing yields p-values ≤0.05, indicating statistical independence between lightning jump and non-jump distributions for these two parameters. Similar changes in mixed phase graupel mass magnitude are observed prior to lightning jumps and non-jump increases in total flash rate. The p-value for graupel mass change is p=0.096, so jump and non-jump distributions for graupel mass change are not found statistically independent using the p=0.05 significance level. Timing of updraft volume, speed and graupel mass increases are found to be 4 to 13 minutes in advance of lightning jump occurrence. Also, severe storms without lightning jumps lack robust mixed phase updrafts, demonstrating that mixed phase updrafts are not always a requirement for severe weather occurrence. Therefore, the results of this study show that lightning jump occurrences are coincident with larger increases in intense mixed phase updraft volume and peak updraft speed than smaller non-jump increases in total flash rate.

  2. Kinematic and Microphysical Significance of Lightning Jumps Versus Non-Jump Increases in Total Flash Rate

    NASA Technical Reports Server (NTRS)

    Schultz, Christopher J.; Carey, Lawrence D.; Schultz, Elise V.; Blakeslee, Richard J.

    2017-01-01

    Thirty-nine thunderstorms are examined using multiple-Doppler, polarimetric and total lightning observations to understand the role of mixed phase kinematics and microphysics in the development of lightning jumps. This sample size is larger than those of previous studies on this topic. The principal result of this study is that lightning jumps are a result of mixed phase updraft intensification. Larger increases in intense updraft volume greater than or equal to 10 m(sup -1) and larger changes in peak updraft speed are observed prior to lightning jump occurrence when compared to other non-jump increases in total ash rate. Wilcoxon-Mann-Whitney Rank Sum testing yields p-values 0.05, indicating statistical independence between lightning jump and non-jump distributions for these two parameters. Similar changes in mixed phase graupel mass magnitude are observed prior to lightning jumps and non-jump increases in total ash rate. The p-value for graupel mass change is p=0.096, so jump and non-jump distributions for graupel mass change are not found statistically independent using the p=0.05 significance level. Timing of updraft volume, speed and graupel mass increases are found to be 4 to 13 minutes in advance of lightning jump occurrence. Also, severe storms without lightning jumps lack robust mixed phase updrafts, demonstrating that mixed phase updrafts are not always a requirement for severe weather occurrence. Therefore, the results of this study show that lightning jump occurrences are coincident with larger increases in intense mixed phase updraft volume and peak updraft speed than smaller non-jump increases in total ash rate.

  3. One-Hertz Waves at Mars: MAVEN Observations

    NASA Astrophysics Data System (ADS)

    Ruhunusiri, Suranga; Halekas, J. S.; Espley, J. R.; Eparvier, F.; Brain, D.; Mazelle, C.; Harada, Y.; DiBraccio, G. A.; Thiemann, E. M. B.; Larson, D. E.; Mitchell, D. L.; Jakosky, B. M.; Sulaiman, A. H.

    2018-05-01

    We perform a survey of 1-Hz waves at Mars utilizing Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft observations for a Martian year. We find that the 1-Hz wave occurrence rate shows an apparent variation caused by masking of the waves by background turbulence during the times when the background turbulence levels are high. To correct for this turbulence masking, we select waves that occur in time intervals where the background turbulence levels are low. We find that the extreme ultraviolet flux does not affect the wave occurrence rate significantly, suggesting that the newly born pickup ions originating in the Mars's exosphere contribute minimally to the 1-Hz wave generation. We find that the wave occurrence rates are higher for low Mach numbers and low beta values than for high Mach numbers and high beta values. Further, we find that a high percentage of 1-Hz waves satisfy the group-standing condition, which suggests that a high percentage of the waves seen as monochromatic waves in the spacecraft frame can be broadband waves in the solar wind frame that have group velocities nearly equal and opposite to the solar wind velocity. We infer that the wave occurrence rate trends with the Mach number and proton beta are a consequence of how the Mach numbers and beta values influence the wave generation and damping or how those parameters affect the group-standing condition. Finally, we find that the 1-Hz waves are equally likely to be found in both the quasi-parallel and the quasi-perpendicular foreshock regions.

  4. Correcting Estimates of the Occurrence Rate of Earth-like Exoplanets for Stellar Multiplicity

    NASA Astrophysics Data System (ADS)

    Cantor, Elliot; Dressing, Courtney D.; Ciardi, David R.; Christiansen, Jessie

    2018-06-01

    One of the most prominent questions in the exoplanet field has been determining the true occurrence rate of potentially habitable Earth-like planets. NASA’s Kepler mission has been instrumental in answering this question by searching for transiting exoplanets, but follow-up observations of Kepler target stars are needed to determine whether or not the surveyed Kepler targets are in multi-star systems. While many researchers have searched for companions to Kepler planet host stars, few studies have investigated the larger target sample. Regardless of physical association, the presence of nearby stellar companions biases our measurements of a system’s planetary parameters and reduces our sensitivity to small planets. Assuming that all Kepler target stars are single (as is done in many occurrence rate calculations) would overestimate our search completeness and result in an underestimate of the frequency of potentially habitable Earth-like planets. We aim to correct for this bias by characterizing the set of targets for which Kepler could have detected Earth-like planets. We are using adaptive optics (AO) imaging to reveal potential stellar companions and near-infrared spectroscopy to refine stellar parameters for a subset of the Kepler targets that are most amenable to the detection of Earth-like planets. We will then derive correction factors to correct for the biases in the larger set of target stars and determine the true frequency of systems with Earth-like planets. Due to the prevalence of stellar multiples, we expect to calculate an occurrence rate for Earth-like exoplanets that is higher than current figures.

  5. Development of a fire weather index using meteorological observations within the Northeast United States

    Treesearch

    Michael J. Erickson; Joseph J. Charney; Brian A. Colle

    2016-01-01

    A fire weather index (FWI) is developed using wildfire occurrence data and Automated Surface Observing System weather observations within a subregion of the northeastern United States (NEUS) from 1999 to 2008. Average values of several meteorological variables, including near-surface temperature, relative humidity, dewpoint, wind speed, and cumulative daily...

  6. An Experimental Study of Small-Scale Variability of Raindrop Size Distribution

    NASA Technical Reports Server (NTRS)

    Tokay, Ali; Bashor, Paul G.

    2010-01-01

    An experimental study of small-scale variability of raindrop size distributions (DSDs) has been carried out at Wallops Island, Virginia. Three Joss-Waldvogel disdrometers were operated at a distance of 0.65, 1.05, and 1.70 km in a nearly straight line. The main purpose of the study was to examine the variability of DSDs and its integral parameters of liquid water content, rainfall, and reflectivity within a 2-km array: a typical size of Cartesian radar pixel. The composite DSD of rain events showed very good agreement among the disdrometers except where there were noticeable differences in midsize and large drops in a few events. For consideration of partial beam filling where the radar pixel was not completely covered by rain, a single disdrometer reported just over 10% more rainy minutes than the rainy minutes when all three disdrometers reported rainfall. Similarly two out of three disdrometers reported5%more rainy minutes than when all three were reporting rainfall. These percentages were based on a 1-min average, and were less for longer averaging periods. Considering only the minutes when all three disdrometers were reporting rainfall, just over one quarter of the observations showed an increase in the difference in rainfall with distance. This finding was based on a 15-min average and was even less for shorter averaging periods. The probability and cumulative distributions of a gamma-fitted DSD and integral rain parameters between the three disdrometers had a very good agreement and no major variability. This was mainly due to the high percentage of light stratiform rain and to the number of storms that traveled along the track of the disdrometers. At a fixed time step, however, both DSDs and integral rain parameters showed substantial variability. The standard deviation (SD) of rain rate was near 3 mm/h, while the SD of reflectivity exceeded 3 dBZ at the longest separation distance. These standard deviations were at 6-min average and were higher at shorter averaging periods. The correlations decreased with increasing separation distance. For rain rate, the correlations were higher than previous gauge-based studies. This was attributed to the differences in data processing and the difference in rainfall characteristics in different climate regions. It was also considered that the gauge sampling errors could be a factor. In this regard, gauge measurements were simulated employing existing disdrometer dataset. While a difference was noticed in cumulative distribution of rain occurrence between the simulated gauge and disdrometer observations, the correlations in simulated gauge measurements did not differ from the disdrometer measurements.

  7. Sand mining impacts on long-term dune erosion in southern Monterey Bay

    USGS Publications Warehouse

    Thornton, E.B.; Sallenger, Abby; Sesto, Juan Conforto; Egley, L.; McGee, Timothy; Parsons, Rost

    2006-01-01

    Southern Monterey Bay was the most intensively mined shoreline (with sand removed directly from the surf zone) in the U.S. during the period from 1906 until 1990, when the mines were closed following hypotheses that the mining caused coastal erosion. It is estimated that the yearly averaged amount of mined sand between 1940 and 1984 was 128,000 m3/yr, which is approximately 50% of the yearly average dune volume loss during this period. To assess the impact of sand mining, erosion rates along an 18 km range of shoreline during the times of intensive sand mining (1940–1990) are compared with the rates after sand mining ceased (1990–2004). Most of the shoreline is composed of unconsolidated sand with extensive sand dunes rising up to a height of 46 m, vulnerable to the erosive forces of storm waves. Erosion is defined here as a recession of the top edge of the dune. Recession was determined using stereo-photogrammetry, and LIDAR and GPS surveys. Long-term erosion rates vary from about 0.5 m/yr at Monterey to 1.5 m/yr in the middle of the range, and then decrease northward. Erosion events are episodic and occur when storm waves and high tides coincide, allowing swash to undercut the dune and resulting in permanent recession. Erosion appears to be correlated with the occurrence of El Niños. The calculated volume loss of the dune in southern Monterey Bay during the 1997–98 El Niño winter was 1,820,000 m3, which is almost seven times the historical annual mean dune erosion of 270,000 m3/yr. The alongshore variation in recession rates appears to be a function of the alongshore gradient in mean wave energy and depletions by sand mining. After cessation of sand mining in 1990, the erosion rates decreased at locations in the southern end of the bay but have not significantly changed at other locations.

  8. Acceptability of residential development in a regional landscape: Potential effects on wildlife occupancy patterns

    USGS Publications Warehouse

    Bettigole, Charles A.; Donovan, Therese; Manning, Robert; Austin, John; Long, Robert

    2014-01-01

    The conversion of natural lands to developed uses may pose the single greatest human threat to global terrestrial biodiversity. Continued human growth and development over the next century will further exacerbate these effects of habitat loss and fragmentation. Natural resource managers are tasked with managing wildlife as a public trust, yet often have little say in land use decisions. Generally speaking, decision makers could benefit from an understanding of what different regulations mean in terms of wildlife distribution. In a previous paper (Bettigole et al., 2013), we surveyed town residents throughout Vermont to measure how respondents feel about a range of development levels within their town boundaries. We estimated the “social carrying capacity for development” – orSKd – for 251 towns in Vermont. SKd provides an estimate of the level of developed land cover classes that town residents deem “acceptable” within their town boundaries. In this paper, we design a framework for linking the town-specific SKd estimates with the wildlife distribution patterns for three wide-ranging mammalian species: American black bear (Ursus americanus), fisher (Martes pennanti), and bobcat (Lynx rufus). We simulated landscape conditions at SKd for each town in Vermont, and then used existing occupancy models for the three target species to spatially map and compare occupancy rates in the baseline year 2000 with occupancy rates at SKd. With nearly 90% of Vermont towns willing to increase developed landcover classes within town boundaries compared to baseline levels, significant state-wide changes in occupancy rates were predicted for all three focal species. Average occupancy rates declined by −15.9% and −3.1% for black bear and bobcats, respectively. Average occupancy rates for fisher increased by 9.0%. This study provides a method for linking development standards within a town with wildlife occurrence. Across towns, the methodology spatially identifies areas that may be at risk of future development, as well as identifying areas where wildlife distribution patterns may face future change as a result of increased human population growth and development.

  9. Occurrence of illicit drugs in two wastewater treatment plants in the South of Italy.

    PubMed

    Cosenza, Alida; Maida, Carmelo Massimo; Piscionieri, Donatella; Fanara, Serena; Di Gaudio, Francesca; Viviani, Gaspare

    2018-05-01

    In this study the occurrence and the behavior of illicit drugs and their metabolites have been investigated for two wastewater treatment plants (WWTPs) (namely, WWTP-1 and WWTP-2) located in Sicily (island of Italy). Samples were analyzed for methamphetamine, cocaine (COC), 3,4-methylenedioxymethamphetamine (MDMA), methadone (METH), 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), 3,4-methylenedioxy amphetamine (MDA); 3,4-methylenedioxy ethylamphetamine (MDEA), 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THC-COOH) and Benzoylecgonine (BEG). The BEG, COC, MOR and THC-COOH were found at the highest concentration in both WWTPs. The Wastewater-based epidemiology calculation for BEG, COC, cannabinoids and THC-COOH was performed. On average, for both plants, population consumes 1.6 and 23.4 dose 1000 inh -1 day -1 of cocaine and cannabis, respectively. For WWTP-1 negative removals of illicit drugs were observed. For WWTP-2 the following average removal efficiencies were obtained: BEG (77.85%), COC (92.34%), CODEINE (64.75%), MOR (90.16%) and THC-COOH (68.64%). Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. Pilonidal sinus in Japan maritime self-defense force at Yokosuka.

    PubMed

    Chijiwa, Tsuyoshi; Suganuma, Toshiyuki; Takigawa, Toshimichi; Edogawa, Seiji; Inoue, Kimitoshi; Yanagida, Shigeki; Hatada, Junichi

    2006-07-01

    Pilonidal sinus is known to be common among soldiers but not among Asian individuals. Few reports have discussed the occurrence of pilonidal sinus in the navy. We analyzed the incidence and etiological factors of 12 cases (11 patients, with 1 recurrence) of pilonidal sinus diagnosed between 1998 and 2004 in Japan Self-Defense Force Hospital Yokosuka. All patients were male, and all lesions were in the sacral area. The patients' average age and body mass index were 29.1 years and 27.4, respectively. The surgical procedures used were primary closures (10 cases, 83.3%) and flaps (two cases, 16.7%), and the number of postoperative hospital days averaged 11.8. Pilonidal sinus was not found to be significantly common among Japan Self-Defense Force personnel in general (7 of 11 patients with pilonidal sinus; not significant); however, it was significantly more common among the crew members of Japan Self-Defense Force ships (seven of seven patients; p < 0.05), which suggests that the on-board lifestyle contributes to the occurrence of pilonidal sinus.

  11. Fumonisins B₁, B₂ and B₃ in corn products, wheat flour and corn oil marketed in Shandong province of China.

    PubMed

    Li, Fenghua; Jiang, Dafeng; Zheng, Fengjia; Chen, Jindong; Li, Wei

    2015-01-01

    In this study a total of 522 samples were collected from Shandong province of China in 2014 and analysed for the occurrence of fumonisin B1 (FB1), FB2 and FB3 by isotope dilution ultrahigh performance liquid chromatography-tandem mass spectrometry. Fumonisins were detected in 98.1% of the corn products, with the average total level of 369.2 μg kg(-1). The individual average values of FB1, FB2 and FB3 in corn products were 268.3, 53.7 and 47.2 μg kg(-1), respectively. The simultaneous occurrence of FB1, FB2 and FB3 was observed in 76.7% of the corn products. Especially, the results demonstrated that the difference in the contamination levels for fumonisins in these three types of corn products was apparent. In addition, 6.2% of the wheat flour samples were contaminated with FB1, with concentrations ranging from 0.3 to 34.6 µg kg(-1). No FB2 or FB3 was detected in wheat flour. In corn oil samples no fumonisins were detected.

  12. Operational Failures and Interruptions in Hospital Nursing

    PubMed Central

    Tucker, Anita L; Spear, Steven J

    2006-01-01

    Objective To describe the work environment of hospital nurses with particular focus on the performance of work systems supplying information, materials, and equipment for patient care. Data Sources Primary observation, semistructured interviews, and surveys of hospital nurses. Study Design We sampled a cross-sectional group of six U.S. hospitals to examine the frequency of work system failures and their impact on nurse productivity. Data Collection We collected minute-by-minute data on the activities of 11 nurses. In addition, we conducted interviews with six of these nurses using questions related to obstacles to care. Finally, we created and administered two surveys in 48 nursing units, one for nurses and one for managers, asking about the frequency of specific work system failures. Principal Findings Nurses we observed experienced an average of 8.4 work system failures per 8-hour shift. The five most frequent types of failures, accounting for 6.4 of these obstacles, involved medications, orders, supplies, staffing, and equipment. Survey questions asking nurses how frequently they experienced these five categories of obstacles yielded similar frequencies. For an average 8-hour shift, the average task time was only 3.1 minutes, and in spite of this, nurses were interrupted mid-task an average of eight times per shift. Conclusions Our findings suggest that nurse effectiveness can be increased by creating improvement processes triggered by the occurrence of work system failures, with the goal of reducing future occurrences. Second, given that nursing work is fragmented and unpredictable, designing processes that are robust to interruption can help prevent errors. PMID:16704505

  13. 26 CFR 1.989(b)-1 - Definition of weighted average exchange rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Definition of weighted average exchange rate. 1... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Export Trade Corporations § 1.989(b)-1 Definition of weighted average exchange rate. For purposes of section 989(b)(3) and (4), the term “weighted average exchange rate...

  14. Association of time of occurrence of electrical heart storms with environmental physical activity.

    PubMed

    Stoupel, Eliiyahu; Kusniec, Jairo; Golovchiner, Gregory; Abramson, Evgeny; Kadmon, Udi; Strasberg, Boris

    2014-08-01

    Many publications in recent decades have reported a temporal link between medical events and environmental physical activity. The aim of this study was to analyze the time of occurrence of electrical heart storms against levels of cosmological parameters. The sample included 82 patients (71 male) with ischemic cardiomyopathy treated with an implantable cardioverter defibrillator at a tertiary medical center in 1999-2012 (5,114 days). The time of occurrence of all electrical heart storms, defined as three or more events of ventricular tachycardia or ventricular fibrillation daily, was recorded from the defibrillator devices. Findings were analyzed against data on solar, geomagnetic, and cosmic ray (neutron) activity for the same time period obtained from space institutions in the United States and Russia. Electrical storms occurred in all months of the year, with a slight decrease in July, August, and September. Most events took place on days with lower-than-average levels of solar and geomagnetic activity and higher-than-average levels of cosmic ray (neutron) activity. There was a significant difference in mean daily cosmic ray activity between the whole observation period and the days of electrical storm activity (P = 0.0001). These data extend earlier findings on the association of the timing of cardiac events and space weather parameters to the most dangerous form of cardiac arrhythmia-electric storms. Further studies are needed to delineate the pathogenetic mechanism underlying this association. ©2014 Wiley Periodicals, Inc.

  15. A new cloud and aerosol layer detection method based on micropulse lidar measurements

    NASA Astrophysics Data System (ADS)

    Zhao, Chuanfeng; Wang, Yuzhao; Wang, Qianqian; Li, Zhanqing; Wang, Zhien; Liu, Dong

    2014-06-01

    This paper introduces a new algorithm to detect aerosols and clouds based on micropulse lidar measurements. A semidiscretization processing technique is first used to inhibit the impact of increasing noise with distance. The value distribution equalization method which reduces the magnitude of signal variations with distance is then introduced. Combined with empirical threshold values, we determine if the signal waves indicate clouds or aerosols. This method can separate clouds and aerosols with high accuracy, although differentiation between aerosols and clouds are subject to more uncertainties depending on the thresholds selected. Compared with the existing Atmospheric Radiation Measurement program lidar-based cloud product, the new method appears more reliable and detects more clouds with high bases. The algorithm is applied to a year of observations at both the U.S. Southern Great Plains (SGP) and China Taihu sites. At the SGP site, the cloud frequency shows a clear seasonal variation with maximum values in winter and spring and shows bimodal vertical distributions with maximum occurrences at around 3-6 km and 8-12 km. The annual averaged cloud frequency is about 50%. The dominant clouds are stratiform in winter and convective in summer. By contrast, the cloud frequency at the Taihu site shows no clear seasonal variation and the maximum occurrence is at around 1 km. The annual averaged cloud frequency is about 15% higher than that at the SGP site. A seasonal analysis of cloud base occurrence frequency suggests that stratiform clouds dominate at the Taihu site.

  16. Indoor radon risk associated to post-tectonic biotite granites from Vila Pouca de Aguiar pluton, northern Portugal.

    PubMed

    Martins, L M O; Gomes, M E P; Teixeira, R J S; Pereira, A J S C; Neves, L J P F

    2016-11-01

    At Vila Pouca de Aguiar area, northern Portugal, crops out a post-tectonic Variscan granite pluton, related with the Régua-Vila Real-Verín fault zone, comprising three types of biotite granites. Among these granites, PSG granite yield the highest average contents of U, probably due to its enrichment in accessory U-bearing minerals such as zircon. In the proximity of faults and joints, these granites are often affected by different degrees of hydrothermal alteration, forming reddish altered rocks, commonly known as "episyenites". These altered rocks are probably associated to the occurrence of hydrothermal processes, which led to uranium enrichment in the most advanced stages of episyenitization. In these granites, both average gamma absorbed dose rates in outdoor and indoor air are higher than those of the world average. Furthermore, even in the worst usage scenario, all these granites can be used as a building material, since their annual effective doses are similar to the limit defined by the European Commission. The geometric mean of radon activity of 91 dwellings located at the Vila Pouca de Aguiar pluton is 568Bqm(-3), exceeding that of other northern Portuguese granites. Measurements carried out during a winter season, indicate that 62.6% of the analysed dwellings yield higher indoor radon average values than the Portuguese legislation limit (400Bqm(-3)), and annual effective doses due higher than the world's average value (1.2mSvy(-1)). The interaction of geogenic, architectural and anthropogenic features is crucial to explain the variance in the geometric mean of radon activity of dwellings from Vila Pouca de Aguiar pluton, but the role of geologic faults is probably the most important decisive factor to increase the indoor radon concentration in dwellings. Hence, the development of awareness campaigns in order to inform population about the incurred radiological risks to radon exposure are highly recommended for this specific area. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Burst of ULF Electric Field Recorded by DEMETER Possibly Related to the Series of Earthquakes Occurred during the Tsunami Over the Indian Region (P19)

    NASA Astrophysics Data System (ADS)

    Gwal, A. K.; Shrivastava, A.

    2006-11-01

    ak_gwal@yahoo.co.in The scientists have found that the accumulation of tectonic energy is localized in certain places and is not universal. Taking into account this hypothesis the authors have studied the sequence of occurrence rate of the earthquakes (M≥5) in the South-East Asian region, as the chronological data related to the occurrence of earthquakes collected in that region for last five years i.e. from 2001 to 2005 have revealed that the disastrous tsunami events which took place on 26th December, 2004 as an effect of Sumatra earthquake( M=9) have increased the occurrence of earthquake frequency for a longer period (which might be due to adjustment of tectonic plates). Observing these facts i.e. sudden enhancement in occurrence rate of earthquakes, the authors have availed this opportunity to further explore the concept of seismoelectromagnetic-ionospheric phenomena, which still needs a lot of statistical evidences, comprising tremendous amount of data to establish it. In this paper the authors have tried to analyze the chain of observations made and data collected and stored month wise w.e.f. 26th December, 2004 to 31st March, 2005 in the region, using DEMETER satellite. Further, efforts have also been made to provide the statistical analysis of the ionospheric variability caused due to detected electromagnetic burst in ULF frequency ranges in the context of natural variability in order to distinguish the variability introduced by other sources. In brief, it could be concluded that there is possibility of getting the electromagnetic precursors in the ionosphere at different frequency ranges due to excess release of tectonic energy as a result of occurrence rate of the earthquakes in the region.

  18. Survey of Ionospheric Pc3-5 ULF Wave Signatures in SuperDARN High Time Resolution Data

    NASA Astrophysics Data System (ADS)

    Shi, X.; Ruohoniemi, J. M.; Baker, J. B. H.; Lin, D.; Bland, E. C.; Hartinger, M. D.; Scales, W. A.

    2018-05-01

    Ionospheric signatures of ultralow frequency (ULF) wave in the Pc3-5 band (1.7-40.0 mHz) were surveyed using ˜6-s resolution data from Super Dual Auroral Radar Network (SuperDARN) radars in the Northern Hemisphere from 2010 to 2016. Numerical experiments were conducted to derive wave period-dependent thresholds for automated detection of ULF waves using the Lomb-Scargle periodogram technique. The spatial occurrence distribution, frequency characteristics, seasonal effects, solar wind condition, and geomagnetic activity level dependence have been studied. Pc5 wave events were found to dominate at high and polar latitudes with a most probable frequency of 2.08 ± 0.07 mHz, while Pc3-4 waves were relatively more common at midlatitudes on the nightside with a most probable frequency of 11.39 ± 0.14 mHz. At high latitudes, the occurrence rate of Pc4-5 waves maximizes in the dusk sector and during winter. These events tend to occur during low geomagnetic activity and northward interplanetary magnetic field. For the category of radially bounded but longitudinally extended Pc4 events in the duskside ionosphere, an internal driving source is suggested. At midlatitudes, the poloidal Pc3-4 occurrence rate maximizes premidnight and during equinox. This tendency becomes more prominent with increasing auroral electrojet (AE) index and during southward interplanetary magnetic field, which suggests that many of these events are Pi2 and Pc3-4 pulsations associated with magnetotail dynamics during active geomagnetic intervals. The overall occurrence rate of Pc3-5 wave events is lowest in summer, which suggests that the ionospheric conductivity plays a role in controlling ULF wave occurrence.

  19. Reducing Adverse Effects During Drug Development: The Example of Lesogaberan and Paresthesia.

    PubMed

    Rydholm, Hans; von Corswant, Christian; Denison, Hans; Jensen, Jörgen M; Lehmann, Anders; Ruth, Magnus; Söderlind, Erik; Aurell-Holmberg, Ann

    2016-04-01

    Lesogaberan, a γ-aminobutyric acid (GABA)B receptor agonist, was developed for the treatment of gastroesophageal reflux disease in patients with a partial response to proton pump inhibitor therapy. A high prevalence of paresthesia was observed in healthy individuals after dosing with lesogaberan in early-phase clinical trials. The aim of this review was to gain further insight into paresthesia caused by lesogaberan by summarizing the relevant preclinical and clinical data. This study was a narrative review of the literature and unpublished data. The occurrence of paresthesia may depend on the route or rate of drug administration; several studies were conducted to test this hypothesis, and formulations were developed to minimize the occurrence of paresthesia. Phase I clinical studies showed that, in healthy individuals, paresthesia occurred soon after administration of lesogaberan in a dose-dependent manner regardless of the route of administration. The occurrence of paresthesia could be decreased by fractionating the dose or reducing the rate of administration. These findings suggest that the initial rate of absorption plays an important part in the development of paresthesia. Modified-release formulations minimize the occurrence of paresthesia while retaining the anti-reflux activity of the drug, as measured by esophageal pH and the number of transient lower esophageal sphincter relaxations. The development of lesogaberan was halted because the effect on gastroesophageal reflux disease symptoms observed in Phase II studies was not considered clinically meaningful in the target patient population. Nevertheless, it is an example of successful formulation development designed to minimize the occurrence of a compound's adverse effect while retaining its pharmacodynamic action. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.

  20. Effects of urbanization on the occurrence of Batrachochytrium dendrobatidis: do urban environments provide refuge from the amphibian chytrid fungus?

    Treesearch

    Daniel Saenz; Taylor L. Hall; Matthew A. Kwiatkowski

    2015-01-01

    Batrachochytrium dendrobatidis (Bd) is a widespread pathogenic fungus that is known to cause the disease, chytridiomycosis, which can be lethal to many amphibians. We compared occurrence rates on spring peepers (Pseudacris crucifer) in urban and forested breeding sites in eastern Texas, USA. All study sites were at...

  1. Spatial distribution and source apportionment of PFASs in surface sediments from five lake regions, China

    PubMed Central

    Qi, Yanjie; Huo, Shouliang; Xi, Beidou; Hu, Shibin; Zhang, Jingtian; He, Zhuoshi

    2016-01-01

    Perfluoroalkyl substances (PFASs) have been found in environment globally. However, studies on PFAS occurrence in sediments of lakes or reservoirs remain relatively scarce. In this study, two hundred and sixty-two surface sediment samples were collected from forty-eight lakes and two reservoirs all over China. Average PFAS concentrations in surface sediments from each lake or reservoir varied from 0.086 ng/g dw to 5.79 ng/g dw with an average of 1.15 ng/g dw. Among five lake regions, average PFAS concentrations for the lakes from Eastern Plain Region were the highest. Perfluorooctanoic acid, perfluoroundecanoic acid and perfluorooctane sulfonic acid (PFOS) were the predominant PFASs in surface sediments. The significant positive correlations between PFAS concentrations and total organic carbon, total nitrogen and total phosphorus contents in sediments revealed the influences of sedimentary characteristics on PFAS occurrence. A two-dimensional hierarchical cluster analysis heat map was depicted to analyze the possible origins of sediments and individual PFAS. The food-packaging, textile, electroplating, firefighting and semiconductor industry emission sources and the precious metals and coating industry emission sources were identified as the main sources by two receptor models, with contributions of 77.7 and 22.3% to the total concentrations of C4-C14- perfluoroalkyl carboxylic acids and PFOS, respectively. PMID:26947748

  2. Variability of chlorination by-product occurrence in water of indoor and outdoor swimming pools.

    PubMed

    Simard, Sabrina; Tardif, Robert; Rodriguez, Manuel J

    2013-04-01

    Swimming is one of the most popular aquatic activities. Just like natural water, public pool water may contain microbiological and chemical contaminants. The purpose of this study was to study the presence of chemical contaminants in swimming pools, in particular the presence of disinfection by-products (DBPs) such as trihalomethanes (THMs), haloacetic acids (HAAs) and inorganic chloramines (CAMi). Fifty-four outdoor and indoor swimming pools were investigated over a period of one year (monthly or bi-weekly sampling, according to the type of pool) for the occurrence of DBPs. The results showed that DBP levels in swimming pools were greater than DBP levels found in drinking water, especially for HAAs. Measured concentrations of THMs (97.9 vs 63.7 μg/L in average) and HAAs (807.6 vs 412.9 μg/L in average) were higher in outdoor pools, whereas measured concentrations of CAMi (0.1 vs 0.8 mg/L in average) were higher in indoor pools. Moreover, outdoor pools with heated water contained more DBPs than unheated pools. Finally, there was significant variability in tTHM, HAA9 and CAMi levels in pools supplied by the same municipal drinking water network, suggesting that individual pool characteristics (number of swimmers) and management strategies play a major role in DBP formation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Programmable noise bandwidth reduction by means of digital averaging

    NASA Technical Reports Server (NTRS)

    Poklemba, John J. (Inventor)

    1993-01-01

    Predetection noise bandwidth reduction is effected by a pre-averager capable of digitally averaging the samples of an input data signal over two or more symbols, the averaging interval being defined by the input sampling rate divided by the output sampling rate. As the averaged sample is clocked to a suitable detector at a much slower rate than the input signal sampling rate the noise bandwidth at the input to the detector is reduced, the input to the detector having an improved signal to noise ratio as a result of the averaging process, and the rate at which such subsequent processing must operate is correspondingly reduced. The pre-averager forms a data filter having an output sampling rate of one sample per symbol of received data. More specifically, selected ones of a plurality of samples accumulated over two or more symbol intervals are output in response to clock signals at a rate of one sample per symbol interval. The pre-averager includes circuitry for weighting digitized signal samples using stored finite impulse response (FIR) filter coefficients. A method according to the present invention is also disclosed.

  4. Occurrence of regulated and non-regulated disinfection by-products in small drinking water systems.

    PubMed

    Guilherme, Stéphanie; Rodriguez, Manuel J

    2014-12-01

    The occurrence of regulated and non-regulated disinfection by-products (DBPs) was investigated in the drinking water of small systems in two provinces in Canada, Newfoundland and Labrador (NL) and Quebec (QC), through an intensive sampling program. Sixteen DBPs were studied: four trihalomethanes (THMs), five haloacetic acids (HAAs), four haloacetonitriles (HANs), one halonitromethane, chloropikrin (CPK) and two haloketones (HKs). Average measured concentrations of these compounds were much higher than those reported in the literature for medium and large systems. The measured average value for THMs was 75 μg L(-1) (Stdv=69μgL(-1)); HAAs, 77 μg L(-1) (Stdv=75 μg L(-1)); HANs, 2.5 μg L(-1) (Stdv=1.8 μg L(-1)); CPK, 0.4 μg L(-1) (Stdv=0.3 μg L(-1)) and HKs, 6.0 μg L(-1) (Stdv=4.5 μg L(-1)). The gap (some 10 times difference) between the average levels of regulated DBPs (THMs, HAAs) and non-regulated DBPs (HANs, CPK and HKs) is comparable to that observed in large systems where the occurrence of the same compounds has been reported. Generally, investigated DBPs followed a comparable seasonal evolution during the year: they decreased between the fall and winter and then increased to eventually reach a maximum in late summer. This trend was less observable in NL than in QC. However, observed seasonal fluctuations of DBPs were less considerable than those observed in medium and large systems located in similar temperate environments reported in the literature. Spatial variations from the plant to the extremities were high and comparable to those observed in large systems, which is surprising, considering the smaller size of distribution networks supplying small communities. Generally speaking, the results support the premise that problems associated with implementing treatment that removes DBP precursors in water submitted to chlorination can increase population exposure to these contaminants in small systems. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Spatial and seasonal responses of precipitation in the Ganges and Brahmaputra river basins to ENSO and Indian Ocean dipole modes: implications for flooding and drought

    NASA Astrophysics Data System (ADS)

    Pervez, M. S.; Henebry, G. M.

    2014-02-01

    We evaluated the spatial and temporal responses of precipitation in the basins as modulated by the El Niño Southern Oscillation (ENSO) and Indian Ocean (IO) dipole modes using observed precipitation records at 43 stations across the Ganges and Brahmaputra basins from 1982 to 2010. Daily observed precipitation records were extracted from Global Surface Summary of the Day dataset and spatial and monthly anomalies were computed. The anomalies were averaged for the years influenced by climate modes combinations. Occurrences of El Niño alone significantly reduced (60% and 88% of baseline in the Ganges and Brahmaputra basins, respectively) precipitation during the monsoon months in the northwestern and central Ganges basin and across the Brahmaputra basin. In contrast, co-occurrence of La Niña and a positive IO dipole mode significantly enhanced (135% and 160% of baseline, respectively) precipitation across both basins. During the co-occurrence of neutral phases in both climate modes (occurring 13 out of 28 yr), precipitation remained below average to average in the agriculturally extensive areas of Haryana, Uttar Pradesh, Bihar, eastern Nepal, and the Rajshahi district in Bangladesh in the Ganges basin and northern Bangladesh, Meghalaya, Assam, and Arunachal Pradesh in the Brahmaputra basin. This pattern implies that a regular water deficit is likely in these areas with implications for the agriculture sector due to its reliance on consistent rainfall for successful production. Major flooding and drought occurred as a consequence of the interactive effects of the ENSO and IO dipole modes, with the sole exception of extreme precipitation and flooding during El Niño events. This observational analysis will facilitate well informed decision making in minimizing natural hazard risks and climate impacts on agriculture, and supports development of strategies ensuring optimized use of water resources in best management practice under changing climate.

  6. Evidence for enhanced debris flow activity in the Northern Calcareous Alps since the 1980s (Plansee, Austria)

    NASA Astrophysics Data System (ADS)

    Dietrich, Andreas; Krautblatter, Michael

    2016-04-01

    From 1950 to 2011 almost 80.000 people lost their lives through the occurrence of debris flow events (Dowling and Santi, 2014). Debris flows occur in all alpine regions due to intensive rainstorms and mobilisable loose debris. Due to their susceptible lithology, the Northern Calcareous Alps are affected by a double digit number of major hazard events per year. Some authors hypothesised a relation between an increasing frequency of heavy rainstorms and an increasing occurrence of landslides in general (Beniston and Douglas, 1996) and debris flows in special (Pelfini and Santilli, 2008), but yet there is only limited evidence. The Plansee catchment in the Ammergauer Alps consists of intensely jointed Upper Triassic Hauptdolomit lithology and therefore shows extreme debris flow activity. To investigate this activity in the last decades, the temporal and spatial development of eight active debris flow fans is examined with GIS and field mapping. The annual rates since the late 1940s are inferred accurately by using aerial photos from 1947, 1952, 1971, 1979, 1987, 2000 and 2010. These rates are compared to the mean Holocene/Lateglacial debris flow volume derived from the most prominent cone. The contact with the underlying till is revealed by electrical resistivity tomography (ERT). It shows that the mean annual debris flow volume has increased there by a factor of 10 from 1947-1952 (0.23 ± 0.07 10³m³/yr) to 1987-2000 (2.41 ± 0.66 10³m³/yr). A similar trend can be seen on all eight fans: mean post-1980 rates exceed pre-1980 rates by a factor of more than three. This increasing debris flow activity coincides with an enhanced rainstorm (def. 35 mm/d) frequency recorded at the nearest meteorological station. Since 1921 the frequency of heavy rainstorms has increased there on average by 10% per decade. Recent debris flow rates are also 2-3 times higher compared to mean Holocene/Lateglacial rates. Furthermore, we state a strong correlation between the non-vegetated catchment area and the annual debris flow volume. This might indicate a decadal positive feedback between enhanced rainstorm frequency and the occurrence of debris flows. The study contributes to a better understanding of the sensitivity of alpine catchments to heavy rainfall events in the context of climate change. Beniston, M., Douglas, G.F., 1996. Impacts of climate change on mountain regions. In: Watson, R.T., Zinyowera, M.C., Moss, R.H., Dokken, D.J. (Eds.), Climate Change 1995. Impacts, Adaptations and Mitigation of Climate Change: Scientific-Technical Analysis. Cambridge Univ. Press, Cambridge, pp. 191-213. Dowling, C.A., Santi, P.M., 2014. Debris flows and their toll on human life: a global analysis of debris-flow fatalities from 1950 to 2011. Nat. Hazards 71, 203-227. doi: 10.1007/s11069-013-0907-4 Pelfini, M., Santilli, M., 2008. Frequency of debris flows and their relation with precipitation: A case study in the Central Alps, Italy. Geomorphology 101, 721-730. doi:10.1016/j.geomorph.2008.04.002

  7. Pathogen and antimicrobial resistance profiles of culture-proven neonatal sepsis in Southwest China, 1990-2014.

    PubMed

    Lu, Qi; Zhou, Min; Tu, Yan; Yao, Yao; Yu, Jialin; Cheng, Shupeng

    2016-10-01

    Neonatal sepsis (NS) sustains high mortality and morbidity in China, but data on the epidemiology and antimicrobial resistance patterns of NS pathogens are limited. The clinical features, aetiology and antimicrobial resistance of culture-proven NS were analysed over a period of 25 years in the metropolitan city of Chongqing in Southwest China. The occurrence rates of neonatal early-onset sepsis (EOS) were found to gradually decrease while late-onset sepsis (LOS) was kept stable from 1990 to 2014. Although coagulase-negative staphylococcus (CoNS) sepsis accounted for most infections, the occurrence rates of CoNS sepsis gradually decreased, especially in EOS. Escherichia coli and Klebsiella were common Gram-negative bacteria. The occurrence rates of E. coli and Klebsiella remained stable in EOS; however, in LOS, those had increased mildly, especially from 2009 to 2014. Although a high-degree resistance to common first- and second-line antimicrobials was observed for the main causative pathogens of NS, the gentamicin-resistance rate declined gradually from the year 2003. Similarly, the ceftazidime-resistance rate of E. coli dropped gradually from the year 2007. The alarmingly high degree of antibiotic resistance calls for urgent evaluation and development of antibiotic policy and protocols for the treatment of NS. Clinicians should strictly control the antibiotics use, decrease invasive manipulations and shorten hospitalisation to prevent LOS. © 2016 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  8. Mesoscale Convective Complexes (MCCs) over the Indonesian Maritime Continent during the ENSO events

    NASA Astrophysics Data System (ADS)

    Trismidianto; Satyawardhana, H.

    2018-05-01

    This study analyzed the mesoscale convective complexes (MCCs) over the Indonesian Maritime Continent (IMC) during the El Niño/Southern Oscillation (ENSO) events for the the15-year period from 2001 to 2015. The MCCs identified by infrared satellite imagery that obtained from the Himawari generation satellite data. This study has reported that the frequencies of the MCC occurrences at the El Niño and La Niña were higher than that of neutral conditions during DJF. Peak of MCC occurrences during DJF at La Niña and neutral condition is in February, while El Niño is in January. ENSO strongly affects the occurrence of MCC during the DJF season. The existences of the MCC were also accompanied by increased rainfall intensity at the locations of the MCC occurrences for all ENSO events. During JJA seasons, the MCC occurrences are always found during neutral conditions, El Niño and La Niña in Indian Ocean. MCC occurring during the JJA season on El Niño and neutral conditions averaged much longer than during the DJF season. In contrast, MCCs occurring in La Niña conditions during the JJA season are more rapidly extinct than during the DJF. It indicates that the influence of MCC during La Niña during the DJF season is stronger than during the JJA season.

  9. Comparing Average Levels and Peak Occurrence of Overnight Sound in the Medical Intensive Care Unit on A-weighted and C-weighted Decibel Scales

    PubMed Central

    Knauert, Melissa; Jeon, Sangchoon; Murphy, Terrence E.; Yaggi, H. Klar; Pisani, Margaret A.; Redeker, Nancy S.

    2016-01-01

    Purpose Sound levels in the intensive care unit (ICU) are universally elevated and are believed to contribute to sleep and circadian disruption. The purpose of this study is to compare overnight ICU sound levels and peak occurrence on A- versus C-weighted scales. Materials and Methods This was a prospective observational study of overnight sound levels in 59 medical ICU patient rooms. Sound level was recorded every 10 seconds on A- and C-weighted decibel scales. Equivalent sound level (Leq) and sound peaks were reported for full and partial night periods. Results The overnight A-weighted Leq of 53.6 dBA was well above World Health Organization (WHO) recommendations; overnight C-weighted Leq was 63.1 dBC (no WHO recommendations). Peak sound occurrence ranged from 1.8 to 23.3 times per hour. Illness severity, mechanical ventilation and delirium were not associated with Leq or peak occurrence. Leq and peak measures for A- and C-weighted decibel scales were significantly different from each other. Conclusions Sound levels in the medical ICU are high throughout the night. Patient factors were not associated with Leq or peak occurrence. Significant discordance between A- and C-weighted values suggests that low frequency sound is a meaningful factor in the medical ICU environment. PMID:27546739

  10. Experience with intubated patients does not affect the accidental extubation rate in pediatric intensive care units and intensive care nurseries.

    PubMed

    Frank, B S; Lewis, R J

    1997-06-01

    Accidental extubation is a potentially serious event for pediatric or neonatal patients with respiratory failure, especially in clinical settings in which personnel capable of performing reintubation may not be readily available. Thus the rate of accidental extubation in small intensive care units that operate without 24-hour in-house physician availability may be an important quality assurance indicator. The objective of this study were to determine the accidental extubation rate at a single small pediatric intensive care unit (PICU) and compare it with published reports. This study was carried out in a six-bed PICU at Washoe Medical Center in Reno, Nevada, with a relatively low level of patient acuity, as measured by PRISM score and the frequency of intubation, and without 24-hour in-house physician availability. All intubated patients admitted during the 5-year period from January 1, 1989 to December 31, 1993 were included. The primary outcome measure was the occurrence of accidental extubation. We observed only two accidental extubations in 1,749 intubated-patient-days (IPD) (0.114 accidental extubations/100 IPD [95% confidence interval 0.014-0.413 accidental extubations/ 100 IPD]). This rate of accidental extubation was compared with data in published reports from neonatal intensive care units (NICUs) and PICUs, which ranged from 0.14 accidental extubations/100 IPD to 4.36 accidental extubations/100 IPD. The dependence of the observed accidental extubation rate on unit size and institutional experience with intubated patients, as measured by the average number of intubated patients, was examined. We found no evidence that the accidental extubation rate is higher in smaller units or units with less institutional experience. Low rates can be achieved in small units with low acuity.

  11. Crimean-Congo hemorrhagic fever and its relationship with climate factors in southeast Iran: a 13-year experience.

    PubMed

    Ansari, Hossein; Shahbaz, Babak; Izadi, Shahrokh; Zeinali, Mohammad; Tabatabaee, Seyyed Mehdi; Mahmoodi, Mahmood; Holakouie Naieni, Kourosh; Mansournia, Mohammad Ali

    2014-06-11

    Crimean-Congo hemorrhagic fever (CCHF) is endemic in southeast Iran. In this study we present the epidemiological features of CCHF and its relationship with climate factors in over a 13-year span. Surveillance system data of CCHF from 2000 to 2012 were obtained from the Province Health Centre of Zahedan University of Medical Sciences in southeast Iran. The climate data were obtained from the climate organization. The seasonal auto-regression integrated moving average (SARIMA) model was used for time series analysis to produce a model as applicable as possible in predicting the variations in the occurrence of the disease. Between 2000 and 2012, 647 confirmed CCHF cases were reported from Sistan-va-Baluchistan province. The total case fatality rate was about 10.0%. Climate variables including mean temperature (°C), accumulated rainfall (mm), and maximum relative humidity (%) were significantly correlated with monthly incidence of CCHF (p <0.05). There was no clear pattern of decline in the reported number of cases within the study's time span. The first spike in the number of CCHF cases in Iran occurred after the first surge of the disease in Pakistan. This study shows the potential of climate indicators as predictive factors in modeling the occurrence of CCHF, even though it has to be appreciated whether there is any need for a practically applicable model. There are also other factors, such as entomological indicators and virological finding that must be considered.

  12. 42 CFR 447.255 - Related information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... assurances described in § 447.253(a), the following information: (a) The amount of the estimated average... which that estimated average rate increased or decreased relative to the average payment rate in effect... and, to the extent feasible, long-term effect the change in the estimated average rate will have on...

  13. Activity Parameters of Subthalamic Nucleus Neurons Selectively Predict Motor Symptom Severity in Parkinson's Disease

    PubMed Central

    Gulberti, Alessandro; Zittel, Simone; Tudor Jones, Adam A.; Fickel, Ulrich; Münchau, Alexander; Köppen, Johannes A.; Gerloff, Christian; Westphal, Manfred; Buhmann, Carsten; Hamel, Wolfgang; Engel, Andreas K.

    2014-01-01

    Parkinson's disease (PD) is a heterogeneous disorder that leads to variable expression of several different motor symptoms. While changes in firing rate, pattern, and oscillation of basal ganglia neurons have been observed in PD patients and experimental animals, there is limited evidence linking them to specific motor symptoms. Here we examined this relationship using extracellular recordings of subthalamic nucleus neurons from 19 PD patients undergoing surgery for deep brain stimulation. For each patient, ≥10 single units and/or multi-units were recorded in the OFF medication state. We correlated the proportion of neurons displaying different activities with preoperative Unified Parkinson's Disease Rating Scale subscores (OFF medication). The mean spectral power at sub-beta frequencies and percentage of units oscillating at beta frequencies were positively correlated with the axial and limb rigidity scores, respectively. The percentage of units oscillating at gamma frequency was negatively correlated with the bradykinesia scores. The mean intraburst rate was positively correlated with both bradykinesia and axial scores, while the related ratio of interspike intervals below/above 10 ms was positively correlated with these symptoms and limb rigidity. None of the activity parameters correlated with tremor. The grand average of all the significantly correlated subthalamic nucleus activities accounted for >60% of the variance of the combined bradykinetic-rigid and axial scores. Our results demonstrate that the occurrence of alterations in the rate and pattern of basal ganglia neurons could partly underlie the variability in parkinsonian phenotype. PMID:24790198

  14. In situ experimental study of carbon monoxide generation by gasoline-powered electric generator in an enclosed space.

    PubMed

    Wang, Liangzhu; Emmerich, Steven J; Persily, Andrew K

    2010-12-01

    On the basis of currently available data, approximately 97% of generator-related carbon monoxide (CO) fatalities are caused by operating currently marketed, carbureted spark-ignited gasoline-powered generators (not equipped with emission controls) in enclosed spaces. To better understand and to reduce the occurrence of these fatalities, research is needed to quantify CO generation rates, develop and test CO emission control devices, and evaluate CO transport and exposure when operating a generator in an enclosed space. As a first step in these efforts, this paper presents measured CO generation rates from a generator without any emission control devices operating in an enclosed space under real weather conditions. This study expands on previously published information from the U.S. Consumer Product Safety Commission. Thirteen separate tests were conducted under different weather conditions at half and full generator load settings. It was found that the CO level in the shed reached a maximum value of 29,300 +/- 580 mg/m3, whereas the oxygen (O2) was depleted to a minimum level of 16.2 +/- 0.02% by volume. For the test conditions of real weather and generator operation, the CO generation and the O2 consumption could be expressed as time-averaged generation/consumption rates. It was also found that the CO generation and O2 consumption rates can be correlated to the O2 levels in the space and the actual load output from the generator. These correlations are shown to agree well with the measurements.

  15. [Clinical analysis of 942 cases of Kawasaki disease].

    PubMed

    Zhang, Wei; Li, Qiu; Zhao, Xiao-dong; Tang, Xue-mei; Wang, Xiao-gang; Wang, Mo; Wu, Dao-qi; Ou, Qian; Yang, Xi-qiang

    2006-05-01

    The study was designed to investigate the clinical characteristics and the effects of therapeutic proposal on Kawasaki disease (KD). Clinical features, diagnosis and treatment for totally 942 patients with KD hospitalized during Jan, 2000 to Dec, 2004 were reviewed. Clinical features of typical and incomplete KD were compared. Also, influential factors for KD resistant to intravenous immune globulin (IVIG) therapy were analyzed. Five hundred and ten cases were followed up for analyzing the prognosis of coronary artery lesion (CAL). (1) 774 cases were diagnosed as typical KD, and 168 cases as incomplete KD. The incidence of infants with incomplete KD was higher than that of infants with typical KD (18.5% vs. 10.1%, P < 0.01). As compared with typical KD, the cases of incomplete KD had a long duration of fever before final diagnosis [(7.7 +/- 2.9) d vs. (7.0 +/- 2.4) d, P < 0.01], high hemoglobin level [Hb, (106.6 +/- 13.4) g/L vs. (103.5 +/- 12.3) g/L, P < 0.01], high hematocrit [Hct, (32.0 +/- 4.3)% vs. (31.0 +/- 4.0)%, P < 0.01], and high prevalence of CAL (23.8% vs. 16.8%, P < 0.05), respectively. The occurrence rate and emerging time of clinical manifestations in incomplete KD and in typical KD were presented, respectively: non-exudative conjunctivitis [occurrence rate, 64.9% vs. 93.5%; emerging time, (4.4 +/- 1.4) d vs. (4.0 +/- 1.6) d, respectively (P < 0.05 or P < 0.01)], erythema and cracking of lips [occurrence rate, 50.6% vs. 94.8%; emerging time, (4.9 +/- 1.4) d vs. (4.5 +/- 1.6) d, respectively (P < 0.05 or P < 0.01)], rash [occurrence rate, 35.1% vs. 87.7%; emerging time, (3.9 +/- 1.9) d vs. (3.4 +/- 1.7) d, respectively (P < 0.05 or P < 0.01)], erythema and edema of extremity [occurrence rate, 26.8% vs. 71.4%; emerging time, (6.7 +/- 1.5) d vs. (5.3 +/- 1.7) d, respectively (P < 0.01)], cervical lymphadenopathy [occurrence rate, 34.5% vs. 68.0%; emerging time, (4.3 +/- 2.5) d vs. (3.6 +/- 2.2) d, respectively (P < 0.05 or P < 0.01)], strawberry tongue [occurrence rate, 31.0% vs. 59.8%; emerging time, (5.6 +/- 2.2) d vs. (4.9 +/- 1.8) d, respectively (P < 0.05 or P < 0.01)], membranous desquamation of fingertips [occurrence rate, 34.5% vs. 56.3%; emerging time, (11.7 +/- 3.3) d vs. (10.3 +/- 2.7) d, respectively (P < 0.01)], and desquamation peri-anus [occurrence rate, 42.9% vs. 50.0%; emerging time, (6.7 +/- 2.7) d vs. (6.9 +/- 2.5) d, respectively (P > 0.05)]. Except for peri-anus desquamation, other clinical manifestations in incomplete KD were sporadical as compared to typical KD. (2) Six per cent (51/857) of cases were resistant to the IVIG therapy. As compared to the group responding to IVIG therapy, high prevalence of CAL (31.4% vs. 17.1%, P < 0.05), long fever duration [(10.6 +/- 3.9) d vs. (7.5 +/- 2.3) d, P < 0.01], low Hb level [(99.9 +/- 14.1) g/L vs. (104.3 +/- 12.4) g/L, P < 0.01], low Hct [(30.1 +/- 4.5)% vs. (31.2 +/- 4.0)%, P < 0.05], low platelet [PLT, (256.9 +/- 142.4) x 10(9)/L vs. (309.7 +/- 131.5) x 10(9)/L, P < 0.05], and low albumin level [ALB, (27.8 +/- 8.4) g/L vs. (33.5 +/- 6.7) g/L, P < 0.01] were found in the group resistant to IVIG therapy, respectively. (3) In patients who received IVIG 1 g/kg and 2 g/kg, the recovery rates from CAL were 83.1% and 89.7% (P > 0.05), respectively. The prevalence of CAL in those without CAL in acute and subacute stages was 0.9% and 3.5% (P > 0.05), respectively, during 2 year-follow-up period. (1) Infants appeared to have more chances to suffer from incomplete KD. Incomplete KD had high prevalence of CAL. The peri-anus desquamation might be an important clue for early diagnosis of incomplete KD. (2) In acute stage, the influential factors for KD resistance to IVIG therapy included prolonged fever, non-elevated PLT, and persistent decrease in Hb, Hct and ALB levels. (3) Children receiving IVIG 1 g/kg and 2 g/kg had the similar effects on recovery and prevention from CAL within the first two years after KD onset.

  16. Plasma protein and supplemental isoleucine in milk replacers for dairy calves.

    PubMed

    Vasquez, K M; Morrison, S Y; Campbell, J M; Drackley, J K

    2017-01-01

    We measured the effects of milk replacers containing 0, 33, 66, or 100% of the total replaceable whey protein as bovine plasma protein (PP), without or with Ile supplementation, on the intake, growth, and health of 124 male Holstein calves for 35d. Milk replacers were formulated to contain 18% crude protein and 20% fat, with contents of Lys and Met equalized. When fed to calves at 1.5% of body weight (dry matter basis) under thermoneutral conditions, diets were predicted to allow average daily gains of 0.55kg/d based on metabolizable energy or 0.40kg/d based on apparent digestible protein. Protein supply was more limiting than energy so that differences in protein use could be detected. Dry matter intakes decreased with increased PP, irrespective of Ile supplementation. Final body weights decreased linearly with increasing PP, regardless of Ile supplementation. Average daily gain tended to be affected in a quadratic manner as PP increased, either with or without Ile supplementation; average daily gain and gain-feed ratio were greatest for calves fed diets containing 33% PP and lowest for calves fed 100% PP. The analyzed Lys content in the milk replacers was variable compared with formulated values, and this may have affected growth results. However, the gain-Lys ratio was affected by an interaction of the linear effect of increasing PP with Ile supplementation: it decreased with increasing PP but was improved by supplementation with Ile for calves fed 100% PP. Body measurements decreased with increasing PP inclusion; only decreased heart girth was reversed with Ile supplementation. The lowest and highest inclusion of PP, regardless of Ile supplementation, decreased the occurrence of scours compared with the control diet (all whey protein). Calves fed the lowest and highest PP without Ile supplementation also had fewer total days of scours in the first 21d. In addition, calves fed 100% PP without supplementation of Ile had fewer days of medication compared with the control diet. Even at the highest PP inclusion, average daily gain was minimally affected if Ile was supplemented. Growth rates, gain-feed ratio, and gain-Lys ratio were decreased at higher PP inclusion, but Ile overcame part of the reduction in gain-Lys ratio for 100% PP. Additional titration studies will have to be conducted to determine optimal PP inclusion rates, with a focus on supplementation of potentially limiting essential AA, as well as effects at higher growth rates. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  17. Forecasting dengue hemorrhagic fever cases using ARIMA model: a case study in Asahan district

    NASA Astrophysics Data System (ADS)

    Siregar, Fazidah A.; Makmur, Tri; Saprin, S.

    2018-01-01

    Time series analysis had been increasingly used to forecast the number of dengue hemorrhagic fever in many studies. Since no vaccine exist and poor public health infrastructure, predicting the occurrence of dengue hemorrhagic fever (DHF) is crucial. This study was conducted to determine trend and forecasting the occurrence of DHF in Asahan district, North Sumatera Province. Monthly reported dengue cases for the years 2012-2016 were obtained from the district health offices. A time series analysis was conducted by Autoregressive integrated moving average (ARIMA) modeling to forecast the occurrence of DHF. The results demonstrated that the reported DHF cases showed a seasonal variation. The SARIMA (1,0,0)(0,1,1)12 model was the best model and adequate for the data. The SARIMA model for DHF is necessary and could applied to predict the incidence of DHF in Asahan district and assist with design public health maesures to prevent and control the diseases.

  18. 77 FR 71601 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... in certain circumstances, e.g., recall of the device, the occurrence of unanticipated adverse effects... Annual Reporting Burden \\1\\ Number of Average Activity/21 CFR Section Number of responses per Total annual burden per Total hours respondents respondent responses response Waivers--812.10 1 1 1 1 1 IDE...

  19. Prevalence and Co-Occurrence of Addictive Behaviors among Russian and Spanish Youth: A Replication Study

    ERIC Educational Resources Information Center

    Tsai, Jennifer; Huh, Jimi; Idrisov, Bulat; Galimov, Artur; Espada, Jose P.; Gonzálvez, María T.; Sussman, Steve

    2016-01-01

    Recently, an addiction matrix measure was assessed among U.S. former alternative high school youth. This presentation seeks to examine the generalizability of findings using this measure among Russian and Spanish high school adolescents. Latent class analysis was used to explore addiction subgroups among adolescents in Russia (average age = 16.27;…

  20. Understanding the Adoption of Ada: Results of an Industry Survey

    DTIC Science & Technology

    1990-05-01

    the next event. Arrival of the data and occurrence of events is not under the control of the software. 7% Online software must respond within human...Better than Average 1 2 3 4 5 6 7 D/K N/A SEI-90-SR-10 47 ,L Section C. CompetItors and the Maret for (APPLICATION AREA

Top