Sample records for average reorientation time

  1. Fundamental experiments on hydride reorientation in zircaloy

    NASA Astrophysics Data System (ADS)

    Colas, Kimberly B.

    In the current study, an in-situ X-ray diffraction technique using synchrotron radiation was used to follow directly the kinetics of hydride dissolution and precipitation during thermomechanical cycles. This technique was combined with conventional microscopy (optical, SEM and TEM) to gain an overall understanding of the process of hydride reorientation. Thus this part of the study emphasized the time-dependent nature of the process, studying large volume of hydrides in the material. In addition, a micro-diffraction technique was also used to study the spatial distribution of hydrides near stress concentrations. This part of the study emphasized the spatial variation of hydride characteristics such as strain and morphology. Hydrided samples in the shape of tensile dog-bones were used in the time-dependent part of the study. Compact tension specimens were used during the spatial dependence part of the study. The hydride elastic strains from peak shift and size and strain broadening were studied as a function of time for precipitating hydrides. The hydrides precipitate in a very compressed state of stress, as measured by the shift in lattice spacing. As precipitation proceeds the average shift decreases, indicating average stress is reduced, likely due to plastic deformation and morphology changes. When nucleation ends the hydrides follow the zirconium matrix thermal contraction. When stress is applied below the threshold stress for reorientation, hydrides first nucleate in a very compressed state similar to that of unstressed hydrides. After reducing the average strain similarly to unstressed hydrides, the average hydride strain reaches a constant value during cool-down to room temperature. This could be due to a greater ease of deforming the matrix due to the applied far-field strain which would compensate for the strains due to thermal contraction. Finally when hydrides reorient, the average hydride strains become tensile during the first precipitation regime and remain constant in the tensile direction during the second precipitation regime. This could be due to the fact that the face of reoriented hydride platelet is in compression once these platelets have grown to a sufficient size. The second goal of this study was to perform a spatially resolved study of the effect of a stress concentration such as a notch or a crack on hydride reorientation. Using SEM and image analysis, it was found that a sharp crack induces a different hydride microstructure than a blunt notch. In the case of sharp crack, hydrides are more localized and align more with the defect than for blunt notches. The hydride connectivity also increases close to a stress concentration which will assist in crack propagation during DHC. Using TEM, the microstructure of hydrides grown near crack tips were observed to be similar to that of circumferential hydrides grown in the bulk. The orientation relationship studied with SEM and micro-X-ray diffraction was found to be in most cases δ(111)// α(0002) for hydrides grown both near and far from stress concentrations. Using the same micro-X-ray diffraction technique local hydride and matrix elastic strains were measured and observed to vary significantly from grain to grain. It was however observed that hydrides grown close to the stress concentration are in tension in the face of the platelet, similar to reoriented hydrides, while those grown far from the stress concentration are in tension, similar to circumferential hydrides. The orders of magnitude of the measured strains in the hydrides and the zirconium matrix compared well to those predicted by finite element models. This study shows that it is possible to study hydride dissolution and precipitation in-situ using time-dependent techniques. It was found that the precipitation temperature is lowered by hydride reorientation. The evolution of hydride strains during precipitation was found to be different for unstressed, stressed and reoriented hydrides. The reoriented hydride fraction and connectivity increase with number of cycles which could lead to more dangerous microstructure for storage of spent fuel. Pre-existing cracks were also found to affect hydride connectivity and morphology which directly impacts DHC and fuel integrity. (Abstract shortened by UMI.).

  2. Reorientation Timescales and Pattern Dynamics for Titan's Dunes: Does the Tail Wag the Dog or the Dragon?

    NASA Astrophysics Data System (ADS)

    Hayes, A. G.; Ewing, R. C.; Cassini Radar Science Team, T.

    2011-12-01

    Fields of bedform patterns persist across many orders of magnitude, from cm-scale sub-aqueous current ripples to km-scale aeolian dunes, and form with surprisingly little difference in expression despite a range of formative environments. Because of the remarkable similarity between and among patterns, extracting information about climate and environment from these patterns is a challenge. For example, crest orientation is not diagnostic of a particular flow regime; similar patterns form under many different flow configurations. On Titan, these challenges have played out with many attempts to reconcile dune-field patterns with modeled and expected wind regimes. We propose that thinking about the change in dune orientation, rather than the orientation itself, can provide new insights on the long-term stability of the dune-field patterns and the formative wind regime. In this work, we apply the re-orientation model presented by Werner and Kocurek [Geology, 1997] to the equatorial dune fields of Titan. We measure variations in pattern parameters (crest spacing, crest length and defect density, which is the number of defect pairs per total crest length) both within and between Titan's dune fields to describe pattern maturity and identify areas where changes in dune orientation are likely to occur (or may already be occurring). Measured defect densities are similar to Earth's largest linear dune fields, such as the Namib Sand Sea and the Simpson Desert. We use measured defect densities in the Werner and Kocurek model to estimate crestline reorientation rates. We find reorientation timescales varying from ten to a hundred thousand times the average migration timescale (time to migrate a bedform one meter, ~1 Titan year according to Tokano (Aeolian Research, 2010)). Well organized patterns have the longest reorientation time scales (~10^5 migration timescales), while the topographically or spatially isolated patches of dunes show the shortest reorientation times (~10^3 migration timescales). In addition, comparisons between spacing and defect density of Titan's dunes and some of the largest fields observed on Earth and Mars reveal that dune patterns on all three planets are geometrically similar, suggesting that growth and organization share common pattern dynamics. Our results suggest that Titan's dunes may react to gross bedform transport averaged over orbital timescales, relaxing the requirement that a single modern wind regime is required to produce the observed pattern.

  3. Reorientations of the large-scale flow in turbulent convection in a cube

    NASA Astrophysics Data System (ADS)

    Foroozani, N.; Niemela, J. J.; Armenio, V.; Sreenivasan, K. R.

    2017-03-01

    Large-eddy simulations of turbulent Rayleigh-Bénard convection were conducted for a fluid of Prandtl number Pr=0.7 confined in a cube, for Rayleigh numbers of 106 and 108. The model solves the unsteady Navier-Stokes equations under the Boussinesq approximation, using a dynamic Smagorinsky model with a Lagrangian averaging technique for the subgrid terms. Under fully developed conditions the flow topology is characterized by a large-scale circulation (LSC) developing in a plane containing one of the diagonals of the cell, while two counter-rotating vortices consequently develop in the other diagonal plane, resulting in a strong inflow at the horizontal midplane. This flow structure is not static, with the LSC undergoing nonperiodic reorientations, or switching, between the two diagonal planes; hence, we supplement the observations of the three-dimensional time-averaged flow structures with single point measurements (time series) to shed light on the dynamics of the reorientations. For all observations, this switching results from a lateral rotation of the LSC in which some finite time spent in a transient state where the large-scale circulation is parallel to one set of side walls; there are, importantly, no observations consistent with so-called cessations of the LSC, in which it decays and then reforms in another plane without such a rotation. The average switching rate for the LSC is in excellent agreement with the results of Bai et al. [K. Bai, D. Ji, and E. Brown, Phys. Rev. E 93, 023117 (2016), 10.1103/PhysRevE.93.023117].

  4. Reorientations of the large-scale flow in turbulent convection in a cube.

    PubMed

    Foroozani, N; Niemela, J J; Armenio, V; Sreenivasan, K R

    2017-03-01

    Large-eddy simulations of turbulent Rayleigh-Bénard convection were conducted for a fluid of Prandtl number Pr=0.7 confined in a cube, for Rayleigh numbers of 10^{6} and 10^{8}. The model solves the unsteady Navier-Stokes equations under the Boussinesq approximation, using a dynamic Smagorinsky model with a Lagrangian averaging technique for the subgrid terms. Under fully developed conditions the flow topology is characterized by a large-scale circulation (LSC) developing in a plane containing one of the diagonals of the cell, while two counter-rotating vortices consequently develop in the other diagonal plane, resulting in a strong inflow at the horizontal midplane. This flow structure is not static, with the LSC undergoing nonperiodic reorientations, or switching, between the two diagonal planes; hence, we supplement the observations of the three-dimensional time-averaged flow structures with single point measurements (time series) to shed light on the dynamics of the reorientations. For all observations, this switching results from a lateral rotation of the LSC in which some finite time spent in a transient state where the large-scale circulation is parallel to one set of side walls; there are, importantly, no observations consistent with so-called cessations of the LSC, in which it decays and then reforms in another plane without such a rotation. The average switching rate for the LSC is in excellent agreement with the results of Bai et al. [K. Bai, D. Ji, and E. Brown, Phys. Rev. E 93, 023117 (2016)PLEEE81539-375510.1103/PhysRevE.93.023117].

  5. Reorientation Timescales and Pattern Dynamics for Titan's Dunes: Does the Tail Wag the Dog or the Dragon?

    NASA Astrophysics Data System (ADS)

    Ewing, R. C.; Hayes, A. G.; McCormick, C.; Ballard, C.; Troy, S. A.

    2012-04-01

    Fields of bedform patterns persist across many orders of magnitude, from cm-scale sub-aqueous current ripples to km-scale aeolian dunes, and form with surprisingly little difference in expression despite a range of formative environments. Because of the remarkable similarity among bedform patterns, extracting information about climate and environment from these patterns is a challenge. For example, crestline orientation is not diagnostic of a particular flow regime; similar patterns form under many different flow configurations. On Titan, these challenges have played out with many attempts to reconcile dune crestline orientation with modeled and expected wind regimes. We propose that thinking about the time-scale of the change in dune orientation, rather than the orientation itself, can provide new insights on the long-term stability of the dune-field patterns and the formative wind regime. In this work, we apply the crestline re-orientation model developed by Werner and Kocurek [Geology, 1997] to the equatorial dune fields of Titan. We use Cassini Synthetic Aperture Radar images processed through a de-noising algorithm recently developed by Lucas et al. [LPSC, 2012] to measure variations in pattern parameters (crest spacing, crest length and defect density, which is the number of defect pairs per total crest length) both within and between Titan's dune fields to describe pattern maturity and identify areas where changes in dune orientation are likely to occur (or may already be occurring). Measured defect densities are similar to Earth's largest linear dune fields, such as the Namib Sand Sea and the Simpson Desert. We use measured defect densities in the Werner and Kocurek model to estimate crestline reorientation rates. We find reorientation timescales varying from ten to a hundred thousand times the average migration timescale (time to migrate a bedform one meter, ~1 Titan year according to Tokano (Aeolian Research, 2010)). Well-organized patterns have the longest reorientation time scales (~105 migration timescales), while the topographically or spatially isolated patches of dunes show the shortest reorientation times (~103 migration timescales). In addition, comparisons between spacing and defect density reveal that the well-organized patterns plot along an expected trend with Earth and Mars' largest, well-organized fields. Patterns on Earth and Mars that have been degraded and broken by environmental change fall off this trend and similarly, so do the isolated dune patterns on Titan fall suggesting changing environmental conditions such as wind regime and/or sediment availability have influenced the dunes on Titan. Crestline orientations in these areas suggest star and crescentic (barchans) morphologies in addition to linear dunes. Our results suggest that Titan's dunes may react to gross bedform transport averaged over orbital timescales, relaxing the requirement that a single modern wind regime is necessary to produce the observed well-organized dune patterns. We find signals of environmental change within the smallest patterns suggesting that the dunes may be recently reoriented or are reorienting to one component of a longer timescale wind regime with a duty cycle that persists over many seasonal cycles.

  6. Probe for high resolution NMR with sample reorientation

    DOEpatents

    Pines, Alexander; Samoson, Ago

    1990-01-01

    An improved NMR probe and method are described which substantially improve the resolution of NMR measurements made on powdered or amorphous or otherwise orientationally disordered samples. The apparatus mechanically varies the orientation of the sample such that the time average of two or more sets of spherical harmonic functions are zero.

  7. Probe for high resolution NMR with sample reorientation

    DOEpatents

    Pines, A.; Samoson, A.

    1990-02-06

    An improved NMR probe and method are described which substantially improve the resolution of NMR measurements made on powdered or amorphous or otherwise orientationally disordered samples. The apparatus mechanically varies the orientation of the sample such that the time average of two or more sets of spherical harmonic functions are zero. 8 figs.

  8. Orientational dynamics in a room temperature ionic liquid: Are angular jumps predominant?

    NASA Astrophysics Data System (ADS)

    Das, Suman; Mukherjee, Biswaroop; Biswas, Ranjit

    2018-05-01

    Reorientational dynamics of the constituent ions in a room temperature ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]), are explored via molecular dynamics simulations, and several features of orientation dynamics are summarized. The anion, [PF6]-, not only exhibits a higher propensity to orientation jumps than the cation, [BMIM]+ but also accesses a wider jump angle distribution and larger peak-angle. Jump and waiting time distributions for both the ions depict power-law dependences, suggesting temporally heterogeneous dynamics for the medium. This heterogeneity feature is further highlighted by the finding that the simulated first rank (ℓ = 1) and second rank (ℓ = 2) average reorientational correlation times reflect a severe break-down of Debye's ℓ(ℓ + 1) law for orientational diffusion in an isotropic homogeneous medium. Simulated average H-bond lifetime resides between the mean orientation jump and waiting times, while the structural H-bond relaxation suggests, as in normal liquids, a pronounced presence of translational motion of the partnering ions. Average simulated jump trajectories reveal a strong rotation-translation coupling and indicate relatively larger changes in spatial and angular arrangements for the anion during an orientation jump. In fact, a closer inspection of all these results points toward more heterogeneous dynamics for [PF6]- than [BMIM]+. This is a new observation and may simply be linked to the ion-size. However, such a generalization warrants further study.

  9. Low gravity reorientation in a scale-model Centaur liquid-hydrogen tank

    NASA Technical Reports Server (NTRS)

    Salzman, J. A.; Masica, W. J.; Lacovic, R. F.

    1973-01-01

    An experiment was conducted to investigate the process of liquid reorientation from one end of a scale-model Centaur liquid-hydrogen tank to the other end by means of low-level accelerations. Prior to reorientation, the liquid was stabilized at the top of the tank at a Bond number of 15. Tanks both with and without ring baffles and with tank radii of 5.5 and 7.0 centimeters were used in the study. Reorientation acceleration values were varied to obtain Bond numbers of 200 and 450. Liquid fill levels of 20 and 70 percent were used. From the data in this study, relations were developed to estimate reorientation event times in unbaffled tanks through the point of final liquid clearing from the top of the tank. The insertion of ring baffles drastically changed the reorientation flow profiles but resulted in only minor differences in the times of tank-top uncovering and liquid collection.

  10. Oscillatory dynamics in the dorsal and ventral attention networks during the reorienting of attention.

    PubMed

    Proskovec, Amy L; Heinrichs-Graham, Elizabeth; Wiesman, Alex I; McDermott, Timothy J; Wilson, Tony W

    2018-05-01

    The ability to reorient attention within the visual field is central to daily functioning, and numerous fMRI studies have shown that the dorsal and ventral attention networks (DAN, VAN) are critical to such processes. However, despite the instantaneous nature of attentional shifts, the dynamics of oscillatory activity serving attentional reorientation remain poorly characterized. In this study, we utilized magnetoencephalography (MEG) and a Posner task to probe the dynamics of attentional reorienting in 29 healthy adults. MEG data were transformed into the time-frequency domain and significant oscillatory responses were imaged using a beamformer. Voxel time series were then extracted from peak voxels in the functional beamformer images. These time series were used to quantify the dynamics of attentional reorienting, and to compute dynamic functional connectivity. Our results indicated strong increases in theta and decreases in alpha and beta activity across many nodes in the DAN and VAN. Interestingly, theta responses were generally stronger during trials that required attentional reorienting relative to those that did not, while alpha and beta oscillations were more dynamic, with many regions exhibiting significantly stronger responses during non-reorienting trials initially, and the opposite pattern during later processing. Finally, stronger functional connectivity was found following target presentation (575-700 ms) between bilateral superior parietal lobules during attentional reorienting. In sum, these data show that visual attention is served by multiple cortical regions within the DAN and VAN, and that attentional reorienting processes are often associated with spectrally-specific oscillations that have largely distinct spatiotemporal dynamics. © 2018 Wiley Periodicals, Inc.

  11. Large Angle Satellite Attitude Maneuvers

    NASA Technical Reports Server (NTRS)

    Cochran, J. E.; Junkins, J. L.

    1975-01-01

    Two methods are proposed for performing large angle reorientation maneuvers. The first method is based upon Euler's rotation theorem; an arbitrary reorientation is ideally accomplished by rotating the spacecraft about a line which is fixed in both the body and in space. This scheme has been found to be best suited for the case in which the initial and desired attitude states have small angular velocities. The second scheme is more general in that a general class of transition trajectories is introduced which, in principle, allows transfer between arbitrary orientation and angular velocity states. The method generates transition maneuvers in which the uncontrolled (free) initial and final states are matched in orientation and angular velocity. The forced transition trajectory is obtained by using a weighted average of the unforced forward integration of the initial state and the unforced backward integration of the desired state. The current effort is centered around practical validation of this second class of maneuvers. Of particular concern is enforcement of given control system constraints and methods for suboptimization by proper selection of maneuver initiation and termination times. Analogous reorientation strategies which force smooth transition in angular momentum and/or rotational energy are under consideration.

  12. Structure and dynamics of water in nonionic reverse micelles: a combined time-resolved infrared and small angle x-ray scattering study.

    PubMed

    van der Loop, Tibert H; Panman, Matthijs R; Lotze, Stephan; Zhang, Jing; Vad, Thomas; Bakker, Huib J; Sager, Wiebke F C; Woutersen, Sander

    2012-07-28

    We study the structure and reorientation dynamics of nanometer-sized water droplets inside nonionic reverse micelles (water/Igepal-CO-520/cyclohexane) with time-resolved mid-infrared pump-probe spectroscopy and small angle x-ray scattering. In the time-resolved experiments, we probe the vibrational and orientational dynamics of the O-D bonds of dilute HDO:H(2)O mixtures in Igepal reverse micelles as a function of temperature and micelle size. We find that even small micelles contain a large fraction of water that reorients at the same rate as water in the bulk, which indicates that the polyethylene oxide chains of the surfactant do not penetrate into the water volume. We also observe that the confinement affects the reorientation dynamics of only the first hydration layer. From the temperature dependent surface-water dynamics, we estimate an activation enthalpy for reorientation of 45 ± 9 kJ mol(-1) (11 ± 2 kcal mol(-1)), which is close to the activation energy of the reorientation of water molecules in ice.

  13. Reorientation Histories of the Terrestrial Planets

    NASA Astrophysics Data System (ADS)

    Keane, J. T.; Matsuyama, I.

    2016-12-01

    The nature of how a planet spins is controlled by the planet's inertia tensor. In a minimum energy rotation state, planets spin about the maximum principal axis of inertia. Yet, the orientation of this axis is not often constant with time. The redistribution of mass within a planet due to both interior processes (e.g. convection, intrusive volcanism) and surface processes (e.g. extrusive volcanism, impacts) can significantly alter the planet's inertia tensor, resulting in the reorientation of the planet. This form of reorientation is also known as true polar wander. Reorientation can directly alter the topography and gravity field of a planet, generate tectonic stresses, change the insolation geometry (affecting climate and volatile stability), and modify the orientation of the planet's magnetic field. Yet, despite its significance, the reorientation histories of many planets is not well constrained. In this work, we present a new technique for using spacecraft-derived, orbital gravity measurements to directly quantify how individual large geologic features reoriented Mercury, Venus, the Moon, and Mars. When coupled with the geologic record for these respective planets, this enables us to determine the reorientation history for each planet. These mark the first comprehensive, multi-episode reorientation chronologies for these planets. The reorientation histories for the Moon and Mercury are similar; the orientation of both planets is strongly controlled by the presence of large remnant bulges (tidal/rotational for the Moon, and likely thermal for Mercury), but significantly modulated by subsequent, large impacts and volcanic events—resulting in 15° of total reorientation after their formation. Mars experienced larger reorientation due to the formation of the Tharsis rise, punctuated by smaller reorientation events from large impacts. Lastly, Venus's diminutive remnant figure and large volcanic edifices result in the largest possible reorientation events, but the exact reorientation chronology is clouded by the uncertainties of Venus's geologic record. The methodology presented here is completely general, and can be applied to any future global gravity maps of other planets or planetary satellites.

  14. Ultrafast inter- and intramolecular vibrational energy transfer between molecules at interfaces studied by time- and polarization-resolved SFG spectroscopy.

    PubMed

    Yamamoto, Susumu; Ghosh, Avishek; Nienhuys, Han-Kwang; Bonn, Mischa

    2010-10-28

    We present experimental results on femtosecond time-resolved surface vibrational spectroscopy aimed at elucidating the sub-picosecond reorientational dynamics of surface molecules. The approach, which relies on polarization- and time-resolved surface sum frequency generation (SFG), provides a general means to monitor interfacial reorientational dynamics through vibrations inherent in surface molecules in their electronic ground state. The technique requires an anisotropic vibrational excitation of surface molecules using orthogonally polarized infrared excitation light. The decay of the resulting anisotropy is followed in real-time. We employ the technique to reveal the reorientational dynamics of vibrational transition dipoles of long-chain primary alcohols on the water surface, and of water molecules at the water-air interface. The results demonstrate that, in addition to reorientational motion of specific molecules or molecular groups at the interface, inter- and intramolecular energy transfer processes can serve to scramble the initial anisotropy very efficiently. In the two exemplary cases demonstrated here, energy transfer occurs much faster than reorientational motion of interfacial molecules. This has important implications for the interpretation of static SFG spectra. Finally, we suggest experimental schemes and strategies to decouple effects resulting from energy transfer from those associated with surface molecular motion.

  15. Water reorientation in the hydration shells of hydrophilic and hydrophobic solutes

    NASA Astrophysics Data System (ADS)

    Laage, Damien; Stirnemann, Guillaume; Hynes, James T.

    2010-06-01

    We discuss some key aspects of our recent theoretical work on water reorientation dynamics, which is important in a wide range of phenomena, including aqueous phase chemical reactions, protein folding, and drug binding to proteins and DNA. It is shown that, contrary to the standard conception that these dynamics are diffusional, the reorientation of a water molecule occurs by sudden, large amplitude angular jumps. The mechanism involves the exchange of one hydrogen bond for another by the reorienting water, and the process can be fruitfully viewed as a chemical reaction. The results for reorientation times, which can be well described analytically, are discussed in the context of the molecular level interpretation of recent ultrafast infrared spectroscopic results, focusing on the concepts of structure making/breaking and solvent ‘icebergs’.

  16. Removing the barrier to the calculation of activation energies: Diffusion coefficients and reorientation times in liquid water.

    PubMed

    Piskulich, Zeke A; Mesele, Oluwaseun O; Thompson, Ward H

    2017-10-07

    General approaches for directly calculating the temperature dependence of dynamical quantities from simulations at a single temperature are presented. The method is demonstrated for self-diffusion and OH reorientation in liquid water. For quantities which possess an activation energy, e.g., the diffusion coefficient and the reorientation time, the results from the direct calculation are in excellent agreement with those obtained from an Arrhenius plot. However, additional information is obtained, including the decomposition of the contributions to the activation energy. These results are discussed along with prospects for additional applications of the direct approach.

  17. Water dynamics in large and small reverse micelles: From two ensembles to collective behavior

    PubMed Central

    Moilanen, David E.; Fenn, Emily E.; Wong, Daryl; Fayer, Michael D.

    2009-01-01

    The dynamics of water in Aerosol-OT reverse micelles are investigated with ultrafast infrared spectroscopy of the hydroxyl stretch. In large reverse micelles, the dynamics of water are separable into two ensembles: slow interfacial water and bulklike core water. As the reverse micelle size decreases, the slowing effect of the interface and the collective nature of water reorientation begin to slow the dynamics of the core water molecules. In the smallest reverse micelles, these effects dominate and all water molecules have the same long time reorientational dynamics. To understand and characterize the transition in the water dynamics from two ensembles to collective reorientation, polarization and frequency selective infrared pump-probe experiments are conducted on the complete range of reverse micelle sizes from a diameter of 1.6–20 nm. The crossover between two ensemble and collective reorientation occurs near a reverse micelle diameter of 4 nm. Below this size, the small number of confined water molecules and structural changes in the reverse micelle interface leads to homogeneous long time reorientation. PMID:19586114

  18. Planar reorientation of a free-free beam in space using embedded electromechanical actuators

    NASA Technical Reports Server (NTRS)

    Kolmanovsky, Ilya V.; Mcclamroch, N. Harris

    1993-01-01

    It is demonstrated that the planar reorientation of a free-free beam in zero gravity space can be accomplished by periodically changing the shape of the beam using embedded electromechanical actuators. The dynamics which determine the shape of the free-free beam is assumed to be characterized by the Euler-Bernoulli equation, including material damping, with appropriate boundary conditions. The coupling between the rigid body motion and the flexible motion is explained using the angular momentum expression which includes rotatory inertia and kinematically exact effects. A control scheme is proposed where the embedded actuators excite the flexible motion of the beam so that it rotates in the desired sense with respect to a fixed inertial reference. Relations are derived which relate the average rotation rate to the amplitudes and the frequencies of the periodic actuation signal and the properties of the beam. These reorientation maneuvers can be implemented by using feedback control.

  19. Time course and auxin sensitivity of cortical microtubule reorientation in maize roots

    NASA Technical Reports Server (NTRS)

    Blancaflor, E. B.; Hasenstein, K. H.

    1995-01-01

    The kinetics of MT [microtubule] reorientation in primary roots of Zea mays cv. Merit, were examined 15, 30, 45, and 60 min after horizontal positioning. Confocal microscopy of longitudinal tissue sections showed no change in MT orientation 15 and 30 min after horizontal placement. However, after 45 and 60 min, MTs of the outer 4-5 cortical cell layers along the lower side were reoriented. In order to test whether MT reorientation during graviresponse is caused by an auxin gradient, we examined the organization of MTs in roots that were incubated for 1 h in solutions containing 10(-9) to 10(-6) M IAA. IAA treatment at 10(-8) M or less showed no major or consistent changes but 10(-7) M IAA resulted in MT reorientation in the cortex. The auxin effect does not appear to be acid-induced since benzoic acid (10(-5) M) did not cause MT reorientation. The region closest to the maturation zone was most sensitive to IAA. The data indicate that early stages of gravity induced curvature occur in the absence of MT reorientation but sustained curvature leads to reoriented MTs in the outer cortex. Growth inhibition along the lower side of graviresponding roots appears to result from asymmetric distribution of auxin following gravistimulation.

  20. Slow molecular dynamics of water in a lyotropic complex fluid studied by deuterium conventional and spin-lattice relaxometry NMR.

    PubMed

    Rodríguez, C R; Pusiol, D J; Figueiredo Neto, A M; Seitter, R-O

    2002-03-01

    A nuclear magnetic resonance study of protons and deuterons in the mesomorphic phases of the micellar lyotropic mixture potassium laurate/1-decanol/heavy water is reported. The slow dynamical behavior of water molecules has been investigated with deuterons spin-lattice relaxation dispersion in the Larmor frequency range 10(3)

  1. The persistence of the gravity signal in flax roots

    NASA Astrophysics Data System (ADS)

    Hasenstein, Karl H.

    Although the presentation time of gravitropism has been studied, no data exist as to how long a reorientation stimulus affects the gravitropic response of a root. We tested the duration of gravitropic curvature in roots of Linum usitatissimum after reversing a one hour, 90 degree gravistimulus by increasing time intervals in vertical orientation before clinorotating the roots and acquiring infrared digital images. Clinorotation was performed either parallel or perpendicular to the gravity vector. Under either condition the gravistimulus affected curvature during clinorotation only between two to three minutes. Maximal curvature after one minute of vertical reorientation was 15 degrees within one hour. After three minutes in vertical orientation the observed curvature was not statistically different from vertically growing roots. In both orientations, maximum curvature occurred after 1hr. Perpendicular (horizontal) clinorotation showed decreasing curvature with increasing reorientation time. Parallel (vertical) clinorotation resulted in greater variability to the reorientation time. These data indicate that the gravity stimulus operates essentially memory free and that clinorotation affects the gravity response. Therefore all aspects of clinorotation need to be studied before an assessment of clinostats for the simulation of microgravity is possible and a time limit for memory effects of mechanostimulation can be determined.

  2. Post-electroconvulsive therapy recovery and reorientation time with methohexital and ketamine: a randomized, longitudinal cross-over design trial

    PubMed Central

    Yen, Tony; Khafaja, Mohamad; Lam, Nicholas; Crumbacher, James; Schrader, Ronald; Rask, John; Billstrand, Mary; Rothfork, Jacob; Abbott, Christopher C.

    2014-01-01

    Objectives Methohexital, a barbiturate anesthetic commonly used for electroconvulsive therapy (ECT), possesses dose-dependent anticonvulsant properties, and its use can interfere with effective seizure therapy in patients with high seizure thresholds. Ketamine, a NMDA-antagonist with epileptogenic properties not broadly used for ECT inductions, is a commonly used induction agent for general anesthesia. Recent studies suggest that the use of ketamine is effective in allowing successful ECT treatment in patients with high seizure thresholds without an increase in side-effects. In this preliminary study, we directly compared the recovery and re-orientation times of subjects receiving ketamine and methohexital for ECTs. Methods Twenty patients were randomized in a cross-over design to receive methohexital and ketamine for ECT inductions in alternating fashion for six trials. Primary outcome measures were recovery time (voluntary movement, respiratory effort, blood pressure, consciousness, and O2 saturation) and re-orientation time. Secondary outcome measures were individual recovery variables, side-effect occurrence, and seizure duration. Results: Overall recovery time was not significantly different between the two treatment arms (F(1,17) = 0.72, P = 0.41). Re-orientation time was faster in the methohexital arm (F(1,17) = 9.23, P = 0.007). Conclusion Ketamine inductions resulted in higher number of side-effects, higher subject dropout rates, and a longer reorientation time with respect to methohexital inductions. No significant difference in post-anesthesia recovery time was found between the ketamine and methohexital arms. Intolerability to ketamine affected a significant proportion of subjects, and suggests that ketamine should remain as an alternative or adjunctive agent for patients with high seizure thresholds. PMID:24755722

  3. Raman study of the molecular motions of pivalic acid: the liquid—plastic phase transition

    NASA Astrophysics Data System (ADS)

    Balevičius, V.; Orel, B.; Hadži, D.

    Raman spectra of pivalic acid in the plastic and liquid phase have been measured. The reorientational correlation times have been evaluated from the ν asCH, νCO and νCC bands as a function of temperature. The reorientational correlation time corresponding to ν as CH and νCC bands is τ < 10 -11 s whilst for the νCO band τ = 4ps ( T = 20°C). The calculated activation energy is 26 KJ mol -1. The reorientation of the carboxylic groups which may be assisted by the proton transfer along the hydrogen bonds in dimers is discussed.

  4. Time-dependent solution for reorientation of rotating tidally deformed visco-elastic bodies

    NASA Astrophysics Data System (ADS)

    Hu, Haiyang; van der Wal, Wouter; Vermeersen, Bert

    2017-04-01

    Many icy satellites or planets contain features which suggest a (past) reorientation of the body, such as the tiger stripes on Enceladus and the heart-shaped Sputnik Planum on Pluto. Most of these icy bodies are tidally locked and this creates a large tidal bulge which is about three times of its centrifugal (equatorial) bulge. To study the reorientation of such rotating tidally deformed body is complicated and most previous studies apply the so-called fluid limit method. The fluid limit approach ignores the viscous response of the body and assumes that it immediately reaches its fluid limit when simulating the reorientation due to a changing load. As a result, this method can only simulate cases when the change in the load is much slower than the dominant viscous modes of the body. For other kinds of load, for instance, a Heaviside load due to an impact which creates an instant relocation of mass, it does not give us a prediction of how the reorientation is accomplished (e.g. How fast? Along which path?). We establish a new method which can give an accurate time-dependent solution for reorientation of rotating tidally deformed bodies. Our method can be applied both semi-analytically or numerically (with finite element method) to include features such as lateral heterogeneity or non-linear material. We also present an extension of our method to simulate the effect of a fossil bulge. With our method, we show that reorientation of a tidally deformed body driven by a positive mass anomaly near the poles has a preference for rotating around the tidal axis instead of towards it, contrary to predictions in previous studies. References Hu, H., W. van der Wal and L.L.A. Vermeersen (2017). A numerical method for reorientation of rotating tidally deformed visco-elastic bodies. Journal of Geophysical Research: Planets, doi:10.1002/2016JE005114, 2016JE005114. Matsuyama, I. and Nimmo, F. (2007). Rotational stability of tidally deformed planetary bodies. Journal of Geophysical Research: Planets, 112(E11).

  5. Optimal chemotaxis in intermittent migration of animal cells

    NASA Astrophysics Data System (ADS)

    Romanczuk, P.; Salbreux, G.

    2015-04-01

    Animal cells can sense chemical gradients without moving and are faced with the challenge of migrating towards a target despite noisy information on the target position. Here we discuss optimal search strategies for a chaser that moves by switching between two phases of motion ("run" and "tumble"), reorienting itself towards the target during tumble phases, and performing persistent migration during run phases. We show that the chaser average run time can be adjusted to minimize the target catching time or the spatial dispersion of the chasers. We obtain analytical results for the catching time and for the spatial dispersion in the limits of small and large ratios of run time to tumble time and scaling laws for the optimal run times. Our findings have implications for optimal chemotactic strategies in animal cell migration.

  6. High-resolution 2-D Bragg diffraction reveal heterogeneous domain transformation behavior in a bulk relaxor ferroelectric

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pramanick, Abhijit, E-mail: apramani@cityu.edu.hk; Stoica, Alexandru D.; An, Ke

    2016-08-29

    In-situ measurement of fine-structure of neutron Bragg diffraction peaks from a relaxor single-crystal using a time-of-flight instrument reveals highly heterogeneous mesoscale domain transformation behavior under applied electric fields. It is observed that only ∼25% of domains undergo reorientation or phase transition contributing to large average strains, while at least 40% remain invariant and exhibit microstrains. Such insights could be central for designing new relaxor materials with better performance and longevity. The current experimental technique can also be applied to resolve complex mesoscale phenomena in other functional materials.

  7. INTRAMOLECULAR MOTION AND REORIENTATIONAL BARRIERS IN 9-FLUORENONE, 4-METHYL-9-FLUORENONE AND 4,5-DIMETHYL-9-FLUORENONE

    EPA Science Inventory

    Carbon-13 nuclear magnetic resonance spin-lattice relaxation times and nuclear Overhauser enhancements were measured as functions of temperature for the hydrogen-bearing carbons in 9-fluorenone, 4-methyl-9-fluorenone, and 4,5-dimethyl-9-fluorenone. Reorientational diffusion const...

  8. Attitude stabilization of a rigid spacecraft using two momentum wheel actuators

    NASA Technical Reports Server (NTRS)

    Krishnan, Hariharan; Mcclamroch, N. Harris; Reyhanoglu, Mahmut

    1993-01-01

    It is well known that three momentum wheel actuators can be used to control the attitude of a rigid spacecraft and that arbitrary reorientation maneuvers of the spacecraft can be accomplished using smooth feedback. If failure of one of the momentum wheel actuators occurs, it is demonstrated that two momentum wheel actuators can be used to control the attitude of a rigid spacecraft and that arbitrary reorientation maneuvers of the spacecraft can be accomplished. Although the complete spacecraft equations are not controllable, the spacecraft equations are small time locally controllable in a reduced nonlinear sense. The reduced spacecraft dynamics cannot be asymptotically stabilized to any equilibrium attitude using a time-variant continuous feedback control law, but discontinuous feedback control strategies are constructed which stabilize any equilibrium attitude of the spacecraft in finite time. Consequently, reorientation of the spacecraft can be accomplished using discontinuous feedback control.

  9. Use of Geometry for Spatial Reorientation in Children Applies Only to Symmetric Spaces

    ERIC Educational Resources Information Center

    Lew, Adina R.; Gibbons, Bryony; Murphy, Caroline; Bremner, J. Gavin

    2010-01-01

    Proponents of the geometric module hypothesis argue that following disorientation, many species reorient by use of macro-environment geometry. It is suggested that attention to the surface layout geometry of natural terrain features may have been selected for over evolutionary time due to the enduring and unambiguous location information it…

  10. Leadership and Organization in Education: Time for a Re-Orientation?

    ERIC Educational Resources Information Center

    Glatter, Ron

    2006-01-01

    The article raises issues about the current direction of the field of educational leadership and management. It argues that we should consider a re-orientation of the field in order to renew its concern with ideas connected with organization, which include viewing organizations as complex adaptive systems and taking an institutional perspective.…

  11. Sexual reorientation therapy: an orthodox perspective.

    PubMed

    Carlton, Clark

    2004-01-01

    This article evaluates the phenomenon of sexual reorientation therapy from the standpoint of Orthodox Christian theology. It is argued that homosexual desire is the product of the fall of mankind and cannot be considered "normal." At the same time, however, reorientation therapies, whether secular or Christian, are inherently reductionistic and fail to address the underlying spiritual pathologies involved in homosexual desire (or any other deep-seated passion). The purpose of therapeia in the Orthodox Church is the psycho-somatic transfiguration of the whole person into the image of Christ, not merely the cessation of homosexual activity or the "reidentification" of one's "lifestyle."

  12. {sup 1}H and {sup 19}F spin-lattice relaxation and CH{sub 3} or CF{sub 3} reorientation in molecular solids containing both H and F atoms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beckmann, Peter A., E-mail: pbeckman@brynmawr.edu; Rheingold, Arnold L.

    2016-04-21

    The dynamics of methyl (CH{sub 3}) and fluoromethyl (CF{sub 3}) groups in organic molecular (van der Waals) solids can be exploited to survey their local environments. We report solid state {sup 1}H and {sup 19}F spin-lattice relaxation experiments in polycrystalline 3-trifluoromethoxycinnamic acid, along with an X-ray diffraction determination of the molecular and crystal structure, to investigate the intramolecular and intermolecular interactions that determine the properties that characterize the CF{sub 3} reorientation. The molecule is of no particular interest; it simply provides a motionless backbone (on the nuclear magnetic resonance (NMR) time scale) to investigate CF{sub 3} reorientation occurring on themore » NMR time scale. The effects of {sup 19}F–{sup 19}F and {sup 19}F–{sup 1}H spin-spin dipolar interactions on the complicated nonexponential NMR relaxation provide independent inputs into determining a model for CF{sub 3} reorientation. As such, these experiments provide much more information than when only one spin species (usually {sup 1}H) is present. In Sec. IV, which can be read immediately after the Introduction without reading the rest of the paper, we compare the barrier to CH{sub 3} and CF{sub 3} reorientation in seven organic solids and separate this barrier into intramolecular and intermolecular components.« less

  13. Spatial reorientation experiments for NMR of solids and partially oriented liquids.

    PubMed

    Martin, Rachel W; Kelly, John E; Collier, Kelsey A

    2015-11-01

    Motional reorientation experiments are extensions of Magic Angle Spinning (MAS) where the rotor axis is changed in order to average out, reintroduce, or scale anisotropic interactions (e.g. dipolar couplings, quadrupolar interactions or chemical shift anisotropies). This review focuses on Variable Angle Spinning (VAS), Switched Angle Spinning (SAS), and Dynamic Angle Spinning (DAS), all of which involve spinning at two or more different angles sequentially, either in successive experiments or during a multidimensional experiment. In all of these experiments, anisotropic terms in the Hamiltonian are scaled by changing the orientation of the spinning sample relative to the static magnetic field. These experiments vary in experimental complexity and instrumentation requirements. In VAS, many one-dimensional spectra are collected as a function of spinning angle. In SAS, dipolar couplings and/or chemical shift anisotropies are reintroduced by switching the sample between two different angles, often 0° or 90° and the magic angle, yielding a two-dimensional isotropic-anisotropic correlation spectrum. Dynamic Angle Spinning (DAS) is a related experiment that is used to simultaneously average out the first- and second-order quadrupolar interactions, which cannot be accomplished by spinning at any unique rotor angle in physical space. Although motional reorientation experiments generally require specialized instrumentation and data analysis schemes, some are accessible with only minor modification of standard MAS probes. In this review, the mechanics of each type of experiment are described, with representative examples. Current and historical probe and coil designs are discussed from the standpoint of how each one accomplishes the particular objectives of the experiment(s) it was designed to perform. Finally, applications to inorganic materials and liquid crystals, which present very different experimental challenges, are discussed. The review concludes with perspectives on how motional reorientation experiments can be applied to current problems in chemistry, molecular biology, and materials science, given the many advances in high-field NMR magnets, fast spinning, and sample preparation realized in recent years. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Dynamic solvophobic effect and its cooperativity in the hydrogen-bonding liquids studied by dielectric and nuclear magnetic resonance relaxation.

    PubMed

    Yamaguchi, Tsuyoshi; Furuhashi, Hiroki; Matsuoka, Tatsuro; Koda, Shinobu

    2008-12-25

    The reorientational relaxation of solvent molecules in the mixture of nonpolar solutes and hydrogen-bonding liquids including water, alcohols, and amides are studied by dielectric and 2H-nuclear magnetic resonance (NMR) spin-lattice relaxations. The retardation of the reorientational motion of the solvent by weak solute-solvent interaction is observed in all the solvent systems. On the other hand, no clear correlation between the strength of the solute-solvent interaction and the slowing down of the solvent motion is found in N,N-dimethylacetamide, which suggests the importance of the hydrogen bonding in the dynamic solvophobic effect. The cooperativity of the reorientational relaxation is investigated by the comparison between the collective relaxation measured by the dielectric spectroscopy and the single-molecular reorientation determined by NMR. The modification of the dielectric relaxation time caused by the dissolution of the solute is larger than that of the single-molecular reorientational relaxation time in all the solvents studied here. The effect of the static correlation between the dipole moments of different molecules is calculated from the static dielectric constant, and the effect of the dynamic correlation is estimated. The difference in the effects of the solutes on the collective and single-molecular reorientational relaxation is mainly ascribed to the dynamic cooperativity in the cases of water and alcohols, which is consistent with the picture on the dynamic solvophobicity derived by our previous theoretical analysis (Yamaguchi, T.; Matsuoka, T.; Koda, S. J. Chem. Phys. 2004, 120, 7590). On the other hand, the static correlation plays the principal role in the case of N-methylformamide.

  15. Liquid hydrogen slosh waves excited by constant reverse gravity acceleration of geyser initiation

    NASA Technical Reports Server (NTRS)

    Hung, R. J.; Shyu, K. L.; Lee, C. C.

    1992-01-01

    The requirement to settle or to position liquid fuel over the outlet end of the spacecraft propellant tank before main engine restart poses a microgravity fluid behavior problem. Resettlement or reorientation of liquid propellant can be accomplished by providing the optimal acceleration to the spacecraft such that the propellant is reoriented over the tank outlet. In this study slosh wave excitation induced by the resettling flowfield during the course of liquid reorientation with the initiation of geyser for liquid-filled levels of 30, 50, 65, 70, and 80 percent have been studied. Characteristics of slosh waves with various frequencies excited are discussed. Slosh wave excitations will affect the fluid stress distribution exerted on the container wall and shift the fluid mass distribution inside the container, which imposes the time-dependent variations in the moment of inertia of the container. This information is important for the spacecraft control during the course of liquid reorientation.

  16. Tectonic tests of proposed polar wander paths for Mars and the moon

    NASA Technical Reports Server (NTRS)

    Grimm, R. E.; Solomon, S. C.

    1986-01-01

    A comparison of the lithospheric stress field predicted for rapid global reorientations against observed tectonic features is used to test the polar wander paths proposed for Mars by Schultz and Lutz-Garihan (1981). A calculation of the reorientation stresses leads to the suggestion that the formation of normal faults or graben in broad regions around the former rotation poles should be the minimum tectonic signature of a reorientation that generates lithospheric stresses in excess of the extensional strength of near-surface material. It is concluded that polar wander of the magnitude and timing envisioned by Schultz and Lutz-Garihan did not occur.

  17. Vibrations and reorientations of H2O molecules in [Sr(H2O)6]Cl2 studied by Raman light scattering, incoherent inelastic neutron scattering and proton magnetic resonance.

    PubMed

    Hetmańczyk, Joanna; Hetmańczyk, Lukasz; Migdał-Mikuli, Anna; Mikuli, Edward; Florek-Wojciechowska, Małgorzata; Harańczyk, Hubert

    2014-04-24

    Vibrational-reorientational dynamics of H2O ligands in the high- and low-temperature phases of [Sr(H2O)6]Cl2 was investigated by Raman Spectroscopy (RS), proton magnetic resonance ((1)H NMR), quasielastic and inelastic incoherent Neutron Scattering (QENS and IINS) methods. Neutron powder diffraction (NPD) measurements, performed simultaneously with QENS, did not indicated a change of the crystal structure at the phase transition (detected earlier by differential scanning calorimetry (DSC) at TC(h)=252.9 K (on heating) and at TC(c)=226.5K (on cooling)). Temperature dependence of the full-width at half-maximum (FWHM) of νs(OH) band at ca. 3248 cm(-1) in the RS spectra indicated small discontinuity in the vicinity of phase transition temperature, what suggests that the observed phase transition may be associated with a change of the H2O reorientational dynamics. However, an activation energy value (Ea) for the reorientational motions of H2O ligands in both phases is nearly the same and equals to ca. 8 kJ mol(-1). The QENS peaks, registered for low temperature phase do not show any broadening. However, in the high temperature phase a small QENS broadening is clearly visible, what implies that the reorientational dynamics of H2O ligands undergoes a change at the phase transition. (1)H NMR line is a superposition of two powder Pake doublets, differentiated by a dipolar broadening, suggesting that there are two types of the water molecules in the crystal lattice of [Sr(H2O)6]Cl2 which are structurally not equivalent average distances between the interacting protons are: 1.39 and 1.18 Å. However, their reorientational dynamics is very similar (τc=3.3⋅10(-10) s). Activation energies for the reorientational motion of these both kinds of H2O ligands have nearly the same values in an experimental error limit: and equal to ca. 40 kJ mole(-1). The phase transition is not seen in the (1)H NMR spectra temperature dependencies. Infrared (IR), Raman (RS) and inelastic incoherent neutron scattering (IINS) spectra were calculated by the DFT method and quite a good agreement with the experimental data was obtained. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Modeling of pulsed propellant reorientation

    NASA Technical Reports Server (NTRS)

    Patag, A. E.; Hochstein, J. I.; Chato, D. J.

    1989-01-01

    Optimization of the propellant reorientation process can provide increased payload capability and extend the service life of spacecraft. The use of pulsed propellant reorientation to optimize the reorientation process is proposed. The ECLIPSE code was validated for modeling the reorientation process and is used to study pulsed reorientation in small-scale and full-scale propellant tanks. A dimensional analysis of the process is performed and the resulting dimensionless groups are used to present and correlate the computational predictions for reorientation performance.

  19. Optimal switching between geocentric and egocentric strategies in navigation

    PubMed Central

    Mahadevan, L.

    2016-01-01

    Animals use a combination of egocentric navigation driven by the internal integration of environmental cues, interspersed with geocentric course correction and reorientation. These processes are accompanied by uncertainty in sensory acquisition of information, planning and execution. Inspired by observations of dung beetle navigational strategies that show switching between geocentric and egocentric strategies, we consider the question of optimal reorientation rates for the navigation of an agent moving along a preferred direction in the presence of multiple sources of noise. We address this using a model that takes the form of a correlated random walk at short time scales that is punctuated by reorientation events leading to a biased random walks at long time scales. This allows us to identify optimal alternation schemes and characterize their robustness in the context of noisy sensory acquisition as well as performance errors linked with variations in environmental conditions and agent–environment interactions. PMID:27493769

  20. Low speed maneuvering flight of the rose-breasted cockatoo (Eolophus roseicapillus). II. Inertial and aerodynamic reorientation.

    PubMed

    Hedrick, T L; Usherwood, J R; Biewener, A A

    2007-06-01

    The reconfigurable, flapping wings of birds allow for both inertial and aerodynamic modes of reorientation. We found evidence that both these modes play important roles in the low speed turning flight of the rose-breasted cockatoo Eolophus roseicapillus. Using three-dimensional kinematics recorded from six cockatoos making a 90 degrees turn in a flight corridor, we developed predictions of inertial and aerodynamic reorientation from estimates of wing moments of inertia and flapping arcs, and a blade-element aerodynamic model. The blade-element model successfully predicted weight support (predicted was 88+/-17% of observed, N=6) and centripetal force (predicted was 79+/-29% of observed, N=6) for the maneuvering cockatoos and provided a reasonable estimate of mechanical power. The estimated torque from the model was a significant predictor of roll acceleration (r(2)=0.55, P<0.00001), but greatly overestimated roll magnitude when applied with no roll damping. Non-dimensional roll damping coefficients of approximately -1.5, 2-6 times greater than those typical of airplane flight dynamics (approximately -0.45), were required to bring our estimates of reorientation due to aerodynamic torque back into conjunction with the measured changes in orientation. Our estimates of inertial reorientation were statistically significant predictors of the measured reorientation within wingbeats (r(2) from 0.2 to 0.37, P<0.0005). Components of both our inertial reorientation and aerodynamic torque estimates correlated, significantly, with asymmetries in the activation profile of four flight muscles: the pectoralis, supracoracoideus, biceps brachii and extensor metacarpi radialis (r(2) from 0.27 to 0.45, P<0.005). Thus, avian flight maneuvers rely on production of asymmetries throughout the flight apparatus rather than in a specific set of control or turning muscles.

  1. Maintenance of electrostatic stabilization in altered tubulin lateral contacts may facilitate formation of helical filaments in foraminifera.

    PubMed

    Bassen, David M; Hou, Yubo; Bowser, Samuel S; Banavali, Nilesh K

    2016-08-19

    Microtubules in foraminiferan protists (forams) can convert into helical filament structures, in which longitudinal intraprotofilament interactions between tubulin heterodimers are thought to be lost, while lateral contacts across protofilaments are still maintained. The coarse geometric features of helical filaments are known through low-resolution negative stain electron microscopy (EM). In this study, geometric restraints derived from these experimental data were used to generate an average atomic-scale helical filament model, which anticipated a modest reorientation in the lateral tubulin heterodimer interface. Restrained molecular dynamics (MD) simulations of the nearest neighbor interactions combined with a Genalized Born implicit solvent model were used to assess the lateral, longitudinal, and seam contacts in 13-3 microtubules and the reoriented lateral contacts in the helical filament model. This electrostatic analysis suggests that the change in the lateral interface in the helical filament does not greatly diminish the lateral electrostatic interaction. After longitudinal dissociation, the 13-3 seam interaction is much weaker than the reoriented lateral interface in the helical filament model, providing a plausible atomic-detail explanation for seam-to-lateral contact transition that enables the transition to a helical filament structure.

  2. Maintenance of electrostatic stabilization in altered tubulin lateral contacts may facilitate formation of helical filaments in foraminifera

    NASA Astrophysics Data System (ADS)

    Bassen, David M.; Hou, Yubo; Bowser, Samuel S.; Banavali, Nilesh K.

    2016-08-01

    Microtubules in foraminiferan protists (forams) can convert into helical filament structures, in which longitudinal intraprotofilament interactions between tubulin heterodimers are thought to be lost, while lateral contacts across protofilaments are still maintained. The coarse geometric features of helical filaments are known through low-resolution negative stain electron microscopy (EM). In this study, geometric restraints derived from these experimental data were used to generate an average atomic-scale helical filament model, which anticipated a modest reorientation in the lateral tubulin heterodimer interface. Restrained molecular dynamics (MD) simulations of the nearest neighbor interactions combined with a Genalized Born implicit solvent model were used to assess the lateral, longitudinal, and seam contacts in 13-3 microtubules and the reoriented lateral contacts in the helical filament model. This electrostatic analysis suggests that the change in the lateral interface in the helical filament does not greatly diminish the lateral electrostatic interaction. After longitudinal dissociation, the 13-3 seam interaction is much weaker than the reoriented lateral interface in the helical filament model, providing a plausible atomic-detail explanation for seam-to-lateral contact transition that enables the transition to a helical filament structure.

  3. Growth and microtubule orientation of Zea mays roots subjected to osmotic stress

    NASA Technical Reports Server (NTRS)

    Blancaflor, E. B.; Hasenstein, K. H.

    1995-01-01

    Previous work has shown that microtubule (MT) reorientation follows the onset of growth inhibition on the lower side of graviresponding roots, indicating that growth reduction can occur independently of MT reorientation. To test this observation further, we examined whether the reduction in growth in response to osmotic stress is correlated with MT reorientation. The distribution and rate of growth in maize roots exposed to 350 mOsm sorbitol and KCl or 5 mM Mes/Tris buffer were measured with a digitizer. After various times roots were processed for indirect immunofluorescence microscopy. Application of sorbitol or KCl had no effect on the organization of MTs in the apical 2 mm of the root but resulted in striking and different effects in the basal region of the root. Sorbitol treatment caused rapid appearance of oval to circular holes in the microtubular array that persisted for at least 9 h. Between 30 min and 4 h of submersion in KCl, MTs in cortical cells 4 mm and farther from the quiescent center began to reorient oblique to the longitudinal axis. After 9 h, the alignment of MTs had shifted to parallel to the root axis but MTs of the epidermal cells remained transverse. In KCl-treated roots MT reorientation appeared to follow a pattern of development similar to that in controls but without elongation. Our data provide additional evidence that MT reorientation is not the cause but a consequence of growth inhibition.

  4. Reorientation and Swimming Stability in Sea Urchin Larvae

    NASA Astrophysics Data System (ADS)

    Wheeler, J.; Chan, K. Y. K.; Anderson, E.; Helfrich, K. R.; Mullineaux, L. S.; Sengupta, A.; Stocker, R.

    2016-02-01

    Many benthic marine invertebrates have two-phase life histories, relying on planktonic larval stages for dispersal and exchange of individuals between adult populations. The dispersal of planktonic larvae is determined by two factors: passive advection by the ambient flow and active motility. By modifying dispersal and ultimately settlement, larval motility influences where and when individuals recruit into benthic communities. Despite its ecological relevance, our understanding of larval motility and behavior in the plankton remains limited, especially regarding the interactions of larval motility and ambient turbulence. As most larvae are smaller than the Kolmogorov scale, they experience ocean turbulence in part as a time-changing viscous torque produced by local fluid shear. This torque causes larval reorientation, impacting swimming direction and potentially dispersal at the macroscale. It is therefore paramount to understand the mechanisms of larval reorientation and the stability of larvae against reorientation. Here we report on the larval reorientation behavior of the sea urchins Arbacia punctulata and Heliocidaris crassispina. Both species have life histories characterized by ontogenetic changes to internal density structure and morphology, which we hypothesized to impact stability. To test this hypothesis, we performed "flip chamber" experiments, in which larvae swim freely in a small chamber that is intermittently inverted, mimicking the overturning experienced by larvae in turbulence. We investigated the role of larval age, body size, species, morphology (number of arms), and motility (live versus dead) on the reorientation dynamics. Our work contributes to a more mechanistic understanding of the role of hydrodynamics in the motility and transport of planktonic larvae.

  5. Rotational and translational dynamics and their relation to hydrogen bond lifetimes in an ionic liquid by means of NMR relaxation time experiments and molecular dynamics simulation

    NASA Astrophysics Data System (ADS)

    Strate, Anne; Neumann, Jan; Overbeck, Viviane; Bonsa, Anne-Marie; Michalik, Dirk; Paschek, Dietmar; Ludwig, Ralf

    2018-05-01

    We report a concerted theoretical and experimental effort to determine the reorientational dynamics as well as hydrogen bond lifetimes for the doubly ionic hydrogen bond +OH⋯O- in the ionic liquid (2-hydroxyethyl)trimethylammonium bis(trifluoromethylsulfonyl)imide [Ch][NTf2] by using a combination of NMR relaxation time experiments, density functional theory (DFT) calculations, and molecular dynamics (MD) simulations. Due to fast proton exchange, the determination of rotational correlation times is challenging. For molecular liquids, 17O-enhanced proton relaxation time experiments have been used to determine the rotational correlation times for the OH vectors in water or alcohols. As an alternative to those expensive isotopic substitution experiments, we employed a recently introduced approach which is providing access to the rotational dynamics from a single NMR deuteron quadrupolar relaxation time experiment. Here, the deuteron quadrupole coupling constants (DQCCs) are obtained from a relation between the DQCC and the δ1H proton chemical shifts determined from a set of DFT calculated clusters in combination with experimentally determined proton chemical shifts. The NMR-obtained rotational correlation times were compared to those obtained from MD simulations and then related to viscosities for testing the applicability of popular hydrodynamic models. In addition, hydrogen bond lifetimes were derived, using hydrogen bond population correlation functions computed from MD simulations. Here, two different time domains were observed: The short-time contributions to the hydrogen lifetimes and the reorientational correlation times have roughly the same size and are located in the picosecond range, whereas the long-time contributions decay with relaxation times in the nanosecond regime and are related to rather slow diffusion processes. The computed average hydrogen bond lifetime is dominated by the long-time process, highlighting the importance and longevity of hydrogen-bonded ion pairs in these ionic liquids.

  6. Mechanistic analysis of the search behaviour of Caenorhabditis elegans

    PubMed Central

    Salvador, Liliana C. M.; Bartumeus, Frederic; Levin, Simon A.; Ryu, William S.

    2014-01-01

    A central question in movement research is how animals use information and movement to promote encounter success. Current random search theory identifies reorientation patterns as key to the compromise between optimizing encounters for both nearby and faraway targets, but how the balance between intrinsic motor programmes and previous environmental experience determines the occurrence of these reorientation behaviours remains unknown. We used high-resolution tracking and imaging data to describe the complete motor behaviour of Caenorhabditis elegans when placed in a novel environment (one in which food is absent). Movement in C. elegans is structured around different reorientation behaviours, and we measured how these contributed to changing search strategies as worms became familiar with their new environment. This behavioural transition shows that different reorientation behaviours are governed by two processes: (i) an environmentally informed ‘extrinsic’ strategy that is influenced by recent experience and that controls for area-restricted search behaviour, and (ii) a time-independent, ‘intrinsic’ strategy that reduces spatial oversampling and improves random encounter success. Our results show how movement strategies arise from a balance between intrinsic and extrinsic mechanisms, that search behaviour in C. elegans is initially determined by expectations developed from previous environmental experiences, and which reorientation behaviours are modified as information is acquired from new environments. PMID:24430127

  7. The relationship between reorientational molecular motions and phase transitions in [Mg(H{sub 2}O){sub 6}](BF{sub 4}){sub 2}, studied with the use of {sup 1}H and {sup 19}F NMR and FT-MIR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mikuli, Edward, E-mail: mikuli@chemia.uj.edu.pl; Hetmańczyk, Joanna; Grad, Bartłomiej

    2015-02-14

    A {sup 1}H and {sup 19}F nuclear magnetic resonance study of [Mg(H{sub 2}O){sub 6}](BF{sub 4}){sub 2} has confirmed the existence of two phase transitions at T{sub c1} ≈ 257 K and T{sub c2} ≈ 142 K, detected earlier by the DSC method. These transitions were reflected by changes in the temperature dependences of both proton and fluorine of second moments M{sub 2}{sup H} and M{sub 2}{sup F} and of spin-lattice relaxation times T{sub 1}{sup H} and T{sub 1}{sup F}. The study revealed anisotropic reorientations of whole [Mg(H{sub 2}O){sub 6}]{sup 2+} cations, reorientations by 180° jumps of H{sub 2}O ligands, andmore » aniso- and isotropic reorientations of BF{sub 4}{sup −} anions. The activation parameters for these motions were obtained. It was found that the phase transition at T{sub c1} is associated with the reorientation of the cation as a whole unit around the C{sub 3} axis and that at T{sub c2} with isotropic reorientation of the BF{sub 4}{sup −} anions. The temperature dependence of the full width at half maximum value of the infrared band of ρ{sub t}(H{sub 2}O) mode (at ∼596 cm{sup −1}) indicated that in phases I and II, all H{sub 2}O ligands in [Mg(H{sub 2}O){sub 6}]{sup 2+} perform fast reorientational motions (180° jumps) with a mean value of activation energy equal to ca 10 kJ mole{sup −1}, what is fully consistent with NMR results. The phase transition at T{sub c1} is associated with a sudden change of speed of fast (τ{sub R} ≈ 10{sup −12} s) reorientational motions of H{sub 2}O ligands. Below T{sub c2} (in phase III), the reorientations of certain part of the H{sub 2}O ligands significantly slow down, while others continue their fast reorientation with an activation energy of ca 2 kJ mole{sup −1}. This fast reorientation cannot be evidenced in NMR relaxation experiments. Splitting of certain IR bands connected with H{sub 2}O ligands at the observed phase transitions suggests a reduction of the symmetry of the octahedral [Mg(H{sub 2}O){sub 6}]{sup 2+} complex cation.« less

  8. Structure, spectroscopy and dynamics of layered H2O and CO2 ices

    USGS Publications Warehouse

    ,; Plattner, Nuria; Meuwly, Markus

    2012-01-01

    Molecular dynamics simulations of structural, spectroscopic and dynamical properties of mixed water–carbon dioxide (H2O–CO2) ices are discussed over temperature ranges relevant to atmospheric and astrophysical conditions. The simulations employ multipolar force fields to represent electrostatic interactions which are essential for spectroscopic and dynamical investigations. It is found that at the water/CO2 interface the water surface acts as a template for the CO2 component. The rotational reorientation times in both bulk phases agree well with experimental observations. A pronounced temperature effect on the CO2 reorientation time is observed between 100 K and 200 K. At the interface, water reorientation times are nearly twice as long compared to water in the bulk. The spectroscopy of such ices is rich in the far-infrared region of the spectrum and can be related to translational and rotational modes. Furthermore, spectroscopic signatures mediated across the water/CO2 interface are found in this frequency range (around 440 cm−1). These results will be particularly important for new airborne experiments such as planned for SOFIA.

  9. Anisotropic 2H-nuclear magnetic resonance spin-lattice relaxation in cerebroside- and phospholipid-cholesterol bilayer membranes.

    PubMed

    Siminovitch, D J; Ruocco, M J; Olejniczak, E T; Das Gupta, S K; Griffin, R G

    1988-09-01

    The axially symmetric powder pattern 2H-nuclear magnetic resonance (NMR) lineshapes observed in the liquid crystalline phase of pure lipid or lipid/cholesterol bilayers are essentially invariant to temperature, or, equivalently, to variations in the correlation times characterizing C-2H bond reorientations. In either of these melted phases, where correlation times for C-2H bond motions are shorter than 10(-7) s, information on the molecular dynamics of the saturated hydrocarbon chain would be difficult to obtain using lineshape analyses alone, and one must resort to other methods, such as the measurement of 2H spin-lattice relaxation rates, in order to obtain dynamic information. In pure lipid bilayers, the full power of the spin-lattice relaxation technique has yet to be realized, since an important piece of information, namely the orientation dependence of the 2H spin-lattice relaxation rates is usually lost due to orientational averaging of T1 by rapid lateral diffusion. Under more favorable circumstances, such as those encountered in the lipid/cholesterol mixtures of this study, the effects of orientational averaging by lateral diffusion are nullified, due to either a marked reduction (by at least an order of magnitude) in the diffusion rate, or a marked increase in the radii of curvature of the liposomes. In either case, the angular dependence of 2H spin-lattice relaxation is accessible to experimental study, and can be used to test models of molecular dynamics in these systems. Simulations of the partially recovered lineshapes indicate that the observed T1 anisotropies are consistent with large amplitude molecular reorientation of the C-2H bond among a finite number of sites. Furthermore, from the observed orientation dependence of the 2H spin-lattice relaxation rates, we conclude that order director fluctuations cannot provide the dominant relaxation pathway for acyl chain deuterons.

  10. How do ants make sense of gravity? A Boltzmann Walker analysis of Lasius niger trajectories on various inclines.

    PubMed

    Khuong, Anaïs; Lecheval, Valentin; Fournier, Richard; Blanco, Stéphane; Weitz, Sébastian; Bezian, Jean-Jacques; Gautrais, Jacques

    2013-01-01

    The goal of this study is to describe accurately how the directional information given by support inclinations affects the ant Lasius niger motion in terms of a behavioral decision. To this end, we have tracked the spontaneous motion of 345 ants walking on a 0.5×0.5 m plane canvas, which was tilted with 5 various inclinations by [Formula: see text] rad ([Formula: see text] data points). At the population scale, support inclination favors dispersal along uphill and downhill directions. An ant's decision making process is modeled using a version of the Boltzmann Walker model, which describes an ant's random walk as a series of straight segments separated by reorientation events, and was extended to take directional influence into account. From the data segmented accordingly ([Formula: see text] segments), this extension allows us to test separately how average speed, segments lengths and reorientation decisions are affected by support inclination and current walking direction of the ant. We found that support inclination had a major effect on average speed, which appeared approximately three times slower on the [Formula: see text] incline. However, we found no effect of the walking direction on speed. Contrastingly, we found that ants tend to walk longer in the same direction when they move uphill or downhill, and also that they preferentially adopt new uphill or downhill headings at turning points. We conclude that ants continuously adapt their decision making about where to go, and how long to persist in the same direction, depending on how they are aligned with the line of maximum declivity gradient. Hence, their behavioral decision process appears to combine klinokinesis with geomenotaxis. The extended Boltzmann Walker model parameterized by these effects gives a fair account of the directional dispersal of ants on inclines.

  11. How Do Ants Make Sense of Gravity? A Boltzmann Walker Analysis of Lasius niger Trajectories on Various Inclines

    PubMed Central

    Khuong, Anaïs; Lecheval, Valentin; Fournier, Richard; Blanco, Stéphane; Weitz, Sébastian; Bezian, Jean-Jacques; Gautrais, Jacques

    2013-01-01

    The goal of this study is to describe accurately how the directional information given by support inclinations affects the ant Lasius niger motion in terms of a behavioral decision. To this end, we have tracked the spontaneous motion of 345 ants walking on a 0.5×0.5 m plane canvas, which was tilted with 5 various inclinations by rad ( data points). At the population scale, support inclination favors dispersal along uphill and downhill directions. An ant's decision making process is modeled using a version of the Boltzmann Walker model, which describes an ant's random walk as a series of straight segments separated by reorientation events, and was extended to take directional influence into account. From the data segmented accordingly ( segments), this extension allows us to test separately how average speed, segments lengths and reorientation decisions are affected by support inclination and current walking direction of the ant. We found that support inclination had a major effect on average speed, which appeared approximately three times slower on the incline. However, we found no effect of the walking direction on speed. Contrastingly, we found that ants tend to walk longer in the same direction when they move uphill or downhill, and also that they preferentially adopt new uphill or downhill headings at turning points. We conclude that ants continuously adapt their decision making about where to go, and how long to persist in the same direction, depending on how they are aligned with the line of maximum declivity gradient. Hence, their behavioral decision process appears to combine klinokinesis with geomenotaxis. The extended Boltzmann Walker model parameterized by these effects gives a fair account of the directional dispersal of ants on inclines. PMID:24204636

  12. Continuous reorientation of synchronous terrestrial planets due to mantle convection

    NASA Astrophysics Data System (ADS)

    Leconte, Jérémy

    2018-03-01

    Many known rocky exoplanets are thought to have been spun down by tidal interactions to a state of synchronous rotation, in which a planet's period of rotation is equal to that of its orbit around its host star. Investigations into atmospheric and surface processes occurring on such exoplanets thus commonly assume that day and night sides are fixed with respect to the surface over geological timescales. Here we use an analytical model to show that true polar wander—where a planetary body's spin axis shifts relative to its surface because of changes in mass distribution—can continuously reorient a synchronous rocky exoplanet. As occurs on Earth, we find that even weak mantle convection in a rocky exoplanet can produce density heterogeneities within the mantle sufficient to reorient the planet. Moreover, we show that this reorientation is made very efficient by the slower rotation rate of a synchronous planet when compared with Earth, which limits the stabilizing effect of rotational and tidal deformations. Furthermore, a relatively weak lithosphere limits its ability to support remnant loads and stabilize against reorientation. Although uncertainties exist regarding the mantle and lithospheric evolution of these worlds, we suggest that the axes of smallest and largest moment of inertia of synchronous exoplanets with active mantle convection change continuously over time, but remain closely aligned with the star-planet and orbital axes, respectively.

  13. Reorientation-effect measurement of the first 2+ state in 12C: Confirmation of oblate deformation

    NASA Astrophysics Data System (ADS)

    Kumar Raju, M.; Orce, J. N.; Navrátil, P.; Ball, G. C.; Drake, T. E.; Triambak, S.; Hackman, G.; Pearson, C. J.; Abrahams, K. J.; Akakpo, E. H.; Al Falou, H.; Churchman, R.; Cross, D. S.; Djongolov, M. K.; Erasmus, N.; Finlay, P.; Garnsworthy, A. B.; Garrett, P. E.; Jenkins, D. G.; Kshetri, R.; Leach, K. G.; Masango, S.; Mavela, D. L.; Mehl, C. V.; Mokgolobotho, M. J.; Ngwetsheni, C.; O'Neill, G. G.; Rand, E. T.; Sjue, S. K. L.; Sumithrarachchi, C. S.; Svensson, C. E.; Tardiff, E. R.; Williams, S. J.; Wong, J.

    2018-02-01

    A Coulomb-excitation reorientation-effect measurement using the TIGRESS γ-ray spectrometer at the TRIUMF/ISAC II facility has permitted the determination of the 〈 21+ ‖ E 2 ˆ ‖21+ 〉 diagonal matrix element in 12C from particle-γ coincidence data and state-of-the-art no-core shell model calculations of the nuclear polarizability. The nuclear polarizability for the ground and first-excited (21+) states in 12C have been calculated using chiral NN N4LO500 and NN+3NF350 interactions, which show convergence and agreement with photo-absorption cross-section data. Predictions show a change in the nuclear polarizability with a substantial increase between the ground state and first excited 21+ state at 4.439 MeV. The polarizability of the 21+ state is introduced into the current and previous Coulomb-excitation reorientation-effect analyses of 12C. Spectroscopic quadrupole moments of QS (21+) = + 0.053 (44) eb and QS (21+) = + 0.08 (3) eb are determined, respectively, yielding a weighted average of QS (21+) = + 0.071 (25) eb, in agreement with recent ab initio calculations. The present measurement confirms that the 21+ state of 12C is oblate and emphasizes the important role played by the nuclear polarizability in Coulomb-excitation studies of light nuclei.

  14. Reorientation from Altered States: Please, More Carefully.

    ERIC Educational Resources Information Center

    Heikkinen, Charles A.

    1989-01-01

    Claims counselors too often appear to forget to reorient clients from altered states of consciousness used in counseling and that failure to reorient can result in unnecessary discomfort for clients. Provides suggestions for when and how to reorient to avoid unwanted, lingering aftereffects. (Author/ABL)

  15. Macroscopic Magnetization Control by Symmetry Breaking of Photoinduced Spin Reorientation with Intense Terahertz Magnetic Near Field

    NASA Astrophysics Data System (ADS)

    Kurihara, Takayuki; Watanabe, Hiroshi; Nakajima, Makoto; Karube, Shutaro; Oto, Kenichi; Otani, YoshiChika; Suemoto, Tohru

    2018-03-01

    We exploit an intense terahertz magnetic near field combined with femtosecond laser excitation to break the symmetry of photoinduced spin reorientation paths in ErFeO3 . We succeed in aligning macroscopic magnetization reaching up to 80% of total magnetization in the sample to selectable orientations by adjusting the time delay between terahertz and optical pump pulses. The spin dynamics are well reproduced by equations of motion, including time-dependent magnetic potential. We show that the direction of the generated magnetization is determined by the transient direction of spin tilting and the magnetic field at the moment of photoexcitation.

  16. Performance evaluation of the inverse dynamics method for optimal spacecraft reorientation

    NASA Astrophysics Data System (ADS)

    Ventura, Jacopo; Romano, Marcello; Walter, Ulrich

    2015-05-01

    This paper investigates the application of the inverse dynamics in the virtual domain method to Euler angles, quaternions, and modified Rodrigues parameters for rapid optimal attitude trajectory generation for spacecraft reorientation maneuvers. The impact of the virtual domain and attitude representation is numerically investigated for both minimum time and minimum energy problems. Owing to the nature of the inverse dynamics method, it yields sub-optimal solutions for minimum time problems. Furthermore, the virtual domain improves the optimality of the solution, but at the cost of more computational time. The attitude representation also affects solution quality and computational speed. For minimum energy problems, the optimal solution can be obtained without the virtual domain with any considered attitude representation.

  17. Model-free estimation of the effective correlation time for C–H bond reorientation in amphiphilic bilayers: {sup 1}H–{sup 13}C solid-state NMR and MD simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferreira, Tiago Mendes, E-mail: tiago.ferreira@fkem1.lu.se; Physical Chemistry, Lund University, P.O. Box 124, SE-221 00 Lund; Ollila, O. H. Samuli

    2015-01-28

    Molecular dynamics (MD) simulations give atomically detailed information on structure and dynamics in amphiphilic bilayer systems on timescales up to about 1 μs. The reorientational dynamics of the C–H bonds is conventionally verified by measurements of {sup 13}C or {sup 2}H nuclear magnetic resonance (NMR) longitudinal relaxation rates R{sub 1}, which are more sensitive to motional processes with correlation times close to the inverse Larmor frequency, typically around 1-10 ns on standard NMR instrumentation, and are thus less sensitive to the 10-1000 ns timescale motion that can be observed in the MD simulations. We propose an experimental procedure for atomicallymore » resolved model-free estimation of the C–H bond effective reorientational correlation time τ{sub e}, which includes contributions from the entire range of all-atom MD timescales and that can be calculated directly from the MD trajectories. The approach is based on measurements of {sup 13}C R{sub 1} and R{sub 1ρ} relaxation rates, as well as {sup 1}H−{sup 13}C dipolar couplings, and is applicable to anisotropic liquid crystalline lipid or surfactant systems using a conventional solid-state NMR spectrometer and samples with natural isotopic composition. The procedure is demonstrated on a fully hydrated lamellar phase of 1-palmitoyl-2-oleoyl-phosphatidylcholine, yielding values of τ{sub e} from 0.1 ns for the methyl groups in the choline moiety and at the end of the acyl chains to 3 ns for the g{sub 1} methylene group of the glycerol backbone. MD simulations performed with a widely used united-atom force-field reproduce the τ{sub e}-profile of the major part of the acyl chains but underestimate the dynamics of the glycerol backbone and adjacent molecular segments. The measurement of experimental τ{sub e}-profiles can be used to study subtle effects on C–H bond reorientational motions in anisotropic liquid crystals, as well as to validate the C–H bond reorientation dynamics predicted in MD simulations of amphiphilic bilayers such as lipid membranes.« less

  18. The role of surface charging during the coadsorption of mercaptohexanol to DNA layers on gold: direct observation of desorption and layer reorientation.

    PubMed

    Arinaga, K; Rant, U; Tornow, M; Fujita, S; Abstreiter, G; Yokoyama, N

    2006-06-20

    We study the coadsorption of mercaptohexanol onto preimmobilized oligonucleotide layers on gold. Monitoring the position of the DNA relative to the surface by optical means directly shows the mercaptohexanol-induced desorption of DNA and the reorientation of surface-tethered strands in situ and in real time. By simultaneously recording the electrochemical electrode potential, we are able to demonstrate that changes in the layer conformation are predominantly of electrostatic origin and can be reversed by applying external bias to the substrate.

  19. Effect of light wavelength on motility and magnetic sensibility of the magnetotactic multicellular prokaryote 'Candidatus Magnetoglobus multicellularis'.

    PubMed

    de Azevedo, Lyvia Vidinho; de Barros, Henrique Lins; Keim, Carolina Neumann; Acosta-Avalos, Daniel

    2013-09-01

    'Candidatus Magnetoglobus multicellularis' is a magnetotactic microorganism composed of several bacterial cells. Presently, it is the best known multicellular magnetotactic prokaryote (MMP). Recently, it has been observed that MMPs present a negative photoresponse to high intensity ultraviolet and violet-blue light. In this work, we studied the movement of 'Candidatus Magnetoglobus multicellularis' under low intensity light of different wavelengths, measuring the average velocity and the time to reorient its trajectory when the external magnetic field changes its direction (U-turn time). Our results show that the mean average velocity is higher for red light (628 nm) and lower for green light (517 nm) as compared to yellow (596 nm) and blue (469 nm) light, and the U-turn time decreased for green light illumination. The light wavelength velocity dependence can be understood as variation in flagella rotation speed, being increased by the red light and decreased by the green light relative to yellow and blue light. It is suggested that the dependence of the U-turn time on light wavelength can be considered a form of light-dependent magnetotaxis, because this time represents the magnetic sensibility of the magnetotactic microorganisms. The cellular and molecular mechanisms for this light-dependent velocity and magnetotaxis are unknown and deserve further studies to understand the biochemical interactions and the ecological roles of the different mechanisms of taxis in MMPs.

  20. Rotational reorientation dynamics of Aerosol-OT reverse micelles formed in near-critical propane

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heitz, M.P.; Bright, F.V.

    1996-06-01

    The rotational reorientation kinetics of two fluorescent solutes (rhodamine 6G, R6G, and rhodamine 101, R101) have been determined in sodium bis(2-ethylhexyl) sulfosuccinate (Aerosol-OT, AOT) reverse micelles formed in liquid and near-critical propane. We show that the amount of water loading ([water]/[AOT], R), continuous phase density, and temperature all influence the solute rotational dynamics. In all cases, the decay of anisotropy data (i.e., frequency-dependent differential polarized phase angle and polarized modulation ratio) are well described by a bi-exponential decay law. We find that the faster rotational correlation times are similar to but slightly less than the values predicted for an individualmore » AOT reverse micelle rotating in propane. The recovered rotational correlation times range from 200 to 500 ps depending on experimental conditions. This faster rotational process is explained in terms of lateral diffusion of the fluorophore along the water/headgroup interfacial region within the reverse micelle. The recovered values for the slower rotational correlation times range from 7 to 18 ns. These larger rotational reorientation times are assigned to varying micelle-micelle (i.e., tail-tail) interactions in the low-density, highly compressible fluid region. We also quantify the contribution of the reverse micellar {open_quotes}aggregate{close_quotes} to the total decay of anisotropy. {copyright} {ital 1996} {ital Society for Applied Spectroscopy}« less

  1. Effects of Angular Frequency During Clinorotation on Mesenchymal Stem Cell Morphology and Migration

    NASA Technical Reports Server (NTRS)

    Luna, Carlos; Yew, Alvin G.; Hsieh, Adam H.

    2015-01-01

    Background/Objectives: Ground-based microgravity simulation can reproduce the apparent effects of weightlessness in spaceflight using clinostats that continuously reorient the gravity vector on a specimen, creating a time-averaged nullification of gravity. In this work, we investigated the effects of clinorotation speed on the morphology, cytoarchitecture, and migration behavior of human mesenchymal stem cells (hMSCs). Methods: We compared cell responses at clinorotation speeds of 0, 30, 60, and 75 rpm over 8 hours in a recently developed lab-on-chip-based clinostat system. Time lapse light microscopy was used to visualize changes in cell morphology during and after cessation of clinorotation. Cytoarchitecture was assessed by actin and vinculin staining, and chemotaxis was examined using time lapse light microscopy of cells in NGF (100 ng/ml) gradients. Results: Among clinorotated groups, cell area distributions indicated a greater inhibition of cell spreading with higher angular frequency (p is less than 0.005), though average cell area at 30 rpm after 8 hours became statistically similar to control (p = 0.794). Cells at 75rpm clinorotation remained viable and were able to re-spread after clinorotation. In chemotaxis chambers clinorotation did not alter migration patterns in elongated cells, but most clinorotated cells exhibited cell retraction, which strongly compromised motility.

  2. Modelling and analysis of bacterial tracks suggest an active reorientation mechanism in Rhodobacter sphaeroides

    PubMed Central

    Rosser, Gabriel; Baker, Ruth E.; Armitage, Judith P.; Fletcher, Alexander G.

    2014-01-01

    Most free-swimming bacteria move in approximately straight lines, interspersed with random reorientation phases. A key open question concerns varying mechanisms by which reorientation occurs. We combine mathematical modelling with analysis of a large tracking dataset to study the poorly understood reorientation mechanism in the monoflagellate species Rhodobacter sphaeroides. The flagellum on this species rotates counterclockwise to propel the bacterium, periodically ceasing rotation to enable reorientation. When rotation restarts the cell body usually points in a new direction. It has been assumed that the new direction is simply the result of Brownian rotation. We consider three variants of a self-propelled particle model of bacterial motility. The first considers rotational diffusion only, corresponding to a non-chemotactic mutant strain. Two further models incorporate stochastic reorientations, describing ‘run-and-tumble’ motility. We derive expressions for key summary statistics and simulate each model using a stochastic computational algorithm. We also discuss the effect of cell geometry on rotational diffusion. Working with a previously published tracking dataset, we compare predictions of the models with data on individual stopping events in R. sphaeroides. This provides strong evidence that this species undergoes some form of active reorientation rather than simple reorientation by Brownian rotation. PMID:24872500

  3. Self-Reorientation Following Colorectal Cancer Treatment - A Grounded Theory Study.

    PubMed

    Johansson, Ann-Caroline B; Axelsson, Malin; Berndtsson, Ina; Brink, Eva

    2015-01-01

    After colorectal cancer (CRC) treatment, people reorganize life in ways that are consistent with their understanding of the illness and their expectations for recovery. Incapacities and abilities that have been lost can initiate a need to reorient the self. To the best of our knowledge, no studies have explicitly focused on the concept of self-reorientation after CRC treatment. The aim of the present study was therefore to explore self-reorientation in the early recovery phase after CRC surgery. Grounded theory analysis was undertaken, using the method presented by Charmaz. The present results explained self-reorientation as the individual attempting to achieve congruence in self-perception. A congruent self-perception meant bringing together the perceived self and the self that was mirrored in the near environs. The results showed that societal beliefs and personal explanations are essential elements of self-reorientation, and that it is therefore important to make them visible.

  4. Microtubule array reorientation in response to hormones does not involve changes in microtubule nucleation modes at the periclinal cell surface

    PubMed Central

    Atkinson, Samantha; Kirik, Angela; Kirik, Viktor

    2014-01-01

    Aligned microtubule arrays spatially organize cell division, trafficking, and determine the direction of cell expansion in plant cells. In response to changes in environmental and developmental signals, cells reorganize their microtubule arrays into new configurations. Here, we tested the role of microtubule nucleation during hormone-induced microtubule array reorientation. We have found that in the process of microtubule array reorientation the ratios between branching, parallel, and de-novo nucleations remained constant, suggesting that the microtubule reorientation mechanism does not involve changes in nucleation modes. In the ton2/fass mutant, which has reduced microtubule branching nucleation frequency and decreased nucleation activity of the γ-tubulin complexes, microtubule arrays were able to reorient. Presented data suggest that reorientation of microtubules into transverse arrays in response to hormones does not involve changes in microtubule nucleation at the periclinal cell surface PMID:25135522

  5. Water tribology on graphene.

    PubMed

    N'guessan, Hartmann E; Leh, Aisha; Cox, Paris; Bahadur, Prashant; Tadmor, Rafael; Patra, Prabir; Vajtai, Robert; Ajayan, Pulickel M; Wasnik, Priyanka

    2012-01-01

    Classical experiments show that the force required to slide liquid drops on surfaces increases with the resting time of the drop, t(rest), and reaches a plateau typically after several minutes. Here we use the centrifugal adhesion balance to show that the lateral force required to slide a water drop on a graphene surface is practically invariant with t(rest). In addition, the drop's three-phase contact line adopts a peculiar micrometric serrated form. These observations agree well with current theories that relate the time effect to deformation and molecular re-orientation of the substrate surface. Such molecular re-orientation is non-existent on graphene, which is chemically homogenous. Hence, graphene appears to provide a unique tribological surface test bed for a variety of liquid drop-surface interactions.

  6. Managerial strategies to reorient hospitals towards health promotion: lessons from organisational theory.

    PubMed

    Röthlin, Florian

    2013-01-01

    Reorienting health services towards health promotion is one of the major health promotion strategies stipulated by the Ottawa Charter). Important contradictions, tensions and barriers to health promotion implementation associated with organisational structures have, thus far, been underexposed in the hospital health promotion discourse. This paper aims at identifying risks and the chances for hospital management to strategically and sustainably reorient their hospitals towards health promotion. The paper combines theories and findings from organisational science and management studies as well as from capacity development in the form of a narrative literature review. The aim is to focus on the conditions hospitals, as organisational systems with a highly professionalised workforce, provide for a strategically managed reorientation towards health promotion. Models and principles helping managers to navigate the difficulties and complexities of health promotion reorientation will be suggested. Hospital managers have to deal with genuine obstacles in the complexity and structural formation of hospital organisations. Against this background, continuous management support, a transformative leadership style, participative strategic management and expert governance can be considered important organisational capacities for the reorientation towards a new concept such as health promotion. This paper discusses managerial strategies, effective structural transformations and important organisational capacities that can contribute to a sustainable reorientation of hospitals towards health promotion. It supports hospital managers in exploring their chances of facilitating and effectively supporting a sustainable health promotion reorientation of their hospitals. The paper provides an innovative approach where the focus is on enhanced possibilities for hospital managers to strategically manage the reorientation towards health promotion.

  7. Dynamics of a Room Temperature Ionic Liquid in Supported Ionic Liquid Membranes vs the Bulk Liquid: 2D IR and Polarized IR Pump-Probe Experiments.

    PubMed

    Shin, Jae Yoon; Yamada, Steven A; Fayer, Michael D

    2017-01-11

    Supported ionic liquid membranes (SILMs) are membranes that have ionic liquids impregnated in their pores. SILMs have been proposed for advanced carbon capture materials. Two-dimensional infrared (2D IR) and polarization selective IR pump-probe (PSPP) techniques were used to investigate the dynamics of reorientation and spectral diffusion of the linear triatomic anion, SeCN - , in poly(ether sulfone) (PES) membranes and room-temperature ionic liquid (RTIL), 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EmimNTf 2 ). The dynamics in the bulk EmimNTf 2 were compared to its dynamics in the SILM samples. Two PES membranes, PES200 and PES30, have pores with average sizes, ∼300 nm and ∼100 nm, respectively. Despite the relatively large pore sizes, the measurements reveal that the reorientation of SeCN - and the RTIL structural fluctuations are substantially slower in the SILMs than in the bulk liquid. The complete orientational randomization, slows from 136 ps in the bulk to 513 ps in the PES30. 2D IR measurements yield three time scales for structural spectral diffusion (SSD), that is, the time evolution of the liquid structure. The slowest decay constant increases from 140 ps in the bulk to 504 ps in the PES200 and increases further to 1660 ps in the PES30. The results suggest that changes at the interface propagate out and influence the RTIL structural dynamics even more than a hundred nanometers from the polymer surface. The differences between the IL dynamics in the bulk and in the membranes suggest that studies of bulk RTIL properties may be poor guides to their use in SILMs in carbon capture applications.

  8. Visually-induced reorientation illusions as a function of age.

    PubMed

    Howard, I P; Jenkin, H L; Hu, G

    2000-09-01

    We reported previously that supine subjects inside a furnished room who are tilted 90 degrees may experience themselves and the room as upright to gravity. We call this the levitation illusion because it creates sensations similar to those experienced in weightlessness. It is an example of a larger class of novel static reorientation illusions that we have explored. Stationary subjects inside a furnished room rotating about a horizontal axis experience complete self rotation about the roll or pitch axis. We call this a dynamic reorientation illusion. We have determined the incidence of static and dynamic reorientation illusions in subjects ranging in age from 9 to 78 yr. Some 90% of subjects of all ages experienced the dynamic reorientation illusion but the percentage of subjects experiencing static reorientation illusions increased with age. We propose that the dynamic illusion depends on a primitive mechanism of visual-vestibular interaction but that static reorientation illusions depend on learned visual cues to the vertical arising from the perceived tops and bottoms of familiar objects and spatial relationships between objects. Older people become more dependent on visual polarity to compensate for loss in vestibular sensitivity. Of 9 astronauts, 4 experienced the levitation illusion. The relationship between susceptibility to reorientation illusions on Earth and in space has still to be determined. We propose that the Space Station will be less disorienting if pictures of familiar objects line the walls.

  9. Nonurgent patients in the emergency department? A French formula to prevent misuse

    PubMed Central

    2010-01-01

    Background Overcrowding in emergency department (EDs) is partly due to the use of EDs by nonurgent patients. In France, the authorities responded to the problem by creating primary care units (PCUs): alternative structures located near hospitals. The aims of the study were to assess the willingness of nonurgent patients to be reoriented to a PCU and to collect the reasons that prompted them to accept or refuse. Methods We carried out a cross sectional survey on patients' use of EDs. The study was conducted in a French hospital ED. Patients were interviewed about their use of health services, ED visits, referrals, activities of daily living, and insurance coverage status. Patients' medical data were also collected. Results 85 patients considered nonurgent by a triage nurse were asked to respond to a questionnaire. Sex ratio was 1.4; mean age was 36.3 +/- 11.7 years. Most patients went to the ED autonomously (76%); one third (31.8%) had consulted a physician. The main reasons for using the ED were difficulty to get an appointment with a general practitioner (22.3%), feelings of pain (68.5%), and the availability of medical services in the ED, like imaging, laboratory tests, and drug prescriptions (37.6%). Traumatisms and wounds were the main medical reasons for going to the ED (43.5%). More than two-thirds of responders (68%) were willing to be reoriented towards PCUs. In the multivariate analysis, only employment and the level of urgency perceived by the patient were associated with the willingness to accept reorientation. Employed persons were 4.5 times more likely to accept reorientation (OR = 4.5 CI (1.6-12.9)). Inversely, persons who perceived a high level of urgency were the least likely to accept reorientation (OR = 0.9 CI (0.8-0.9). Conclusions Our study provides information on the willingness of ED patients to accept reorientation and shows the limits of its feasibility. Alternative structures such as PCUs near the ED seem to respond appropriately to the growing demands of nonurgent patients. Reorientation, however, will be successful only if the new structures adapt their opening hours to the needs of nonurgent patients and if their physicians can perform specific technical skills. PMID:20230602

  10. Time-dependent combinatory effects of active mechanical loading and passive topographical cues on cell orientation.

    PubMed

    Wang, Qian; Huang, Hanyang; Wei, Kang; Zhao, Yi

    2016-10-01

    Mechanical stretching and topographical cues are both effective mechanical stimulations for regulating cell morphology, orientation, and behaviors. The competition of these two mechanical stimulations remains largely underexplored. Previous studies have suggested that a small cyclic mechanical strain is not able to reorient cells that have been pre-aligned by relatively large linear microstructures, but can reorient those pre-aligned by small linear micro/nanostructures if the characteristic dimension of these structures is below a certain threshold. Likewise, for micro/nanostructures with a given characteristic dimension, the strain must exceed a certain magnitude to overrule the topographic cues. There are however no in-depth investigations of such "thresholds" due to the lack of close examination of dynamic cell orientation during and shortly after the mechanical loading. In this study, the time-dependent combinatory effects of active and passive mechanical stimulations on cell orientation are investigated by developing a micromechanical stimulator. The results show that the cells pre-aligned by linear micro/nanostructures can be altered by cyclic in-plane strain, regardless of the structure size. During the loading, the micro/nanostructures can resist the reorientation effects by cyclic in-plane strain while the resistive capability (measured by the mean orientation angle change and the reorientation speed) increases with the increasing characteristic dimension. The micro/nanostructures also can recover the cell orientation after the cessation of cyclic in-plane strain, while the recovering capability increases with the characteristic dimension. The previously observed thresholds are largely dependent on the observation time points. In order to accurately evaluate the combinatory effects of the two mechanical stimulations, observations during the active loading with a short time interval or endpoint observations shortly after the loading are preferred. This study provides a microengineering solution to investigate the time-dependent combinatory effects of the active and passive mechanical stimulations and is expected to enhance our understanding of cell responses to complex mechanical environments. Biotechnol. Bioeng. 2016;113: 2191-2201. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Modeling of impulsive propellant reorientation

    NASA Technical Reports Server (NTRS)

    Hochstein, John I.; Patag, Alfredo E.; Chato, David J.

    1988-01-01

    The impulsive propellant reorientation process is modeled using the (Energy Calculations for Liquid Propellants in a Space Environment (ECLIPSE) code. A brief description of the process and the computational model is presented. Code validation is documented via comparison to experimentally derived data for small scale tanks. Predictions of reorientation performance are presented for two tanks designed for use in flight experiments and for a proposed full scale OTV tank. A new dimensionless parameter is developed to correlate reorientation performance in geometrically similar tanks. Its success is demonstrated.

  12. Self-diffusion studies by intra- and inter-molecular spin-lattice relaxometry using field-cycling: Liquids, plastic crystals, porous media, and polymer segments.

    PubMed

    Kimmich, Rainer; Fatkullin, Nail

    2017-08-01

    Field-cycling NMR relaxometry is a well-established technique for probing molecular dynamics in a frequency range from typically a few kHz up to several tens of MHz. For the interpretation of relaxometry data, it is quite often assumed that the spin-lattice relaxation process is of an intra-molecular nature so that rotational fluctuations dominate. However, dipolar interactions as the main type of couplings between protons and other dipolar species without quadrupole moments can imply appreciable inter-molecular contributions. These fluctuate due to translational displacements and to a lesser degree also by rotational reorientations in the short-range limit. The analysis of the inter-molecular proton spin-lattice relaxation rate thus permits one to evaluate self-diffusion variables such as the diffusion coefficient or the mean square displacement on a time scale from nanoseconds to several hundreds of microseconds. Numerous applications to solvents, plastic crystals and polymers will be reviewed. The technique is of particular interest for polymer dynamics since inter-molecular spin-lattice relaxation diffusometry bridges the time scales of quasi-elastic neutron scattering and field-gradient NMR diffusometry. This is just the range where model-specific intra-coil mechanisms are assumed to occur. They are expected to reveal themselves by characteristic power laws for the time-dependence of the mean-square segment displacement. These can be favorably tested on this basis. Results reported in the literature will be compared with theoretical predictions. On the other hand, there is a second way for translational diffusion phenomena to affect the spin-lattice relaxation dispersion. If rotational diffusion of molecules is restricted, translational diffusion properties can be deduced even from molecular reorientation dynamics detected by intra-molecular spin-lattice relaxation. This sort of scenario will be relevant for adsorbates on surfaces or polymer segments under entanglement and chain connectivity constraints. Under such conditions, reorientations will be correlated with translational displacements leading to the so-called RMTD relaxation process (reorientation mediated by translational displacements). Applications to porous glasses, protein solutions, lipid bilayers, and clays will be discussed. Finally, we will address the intriguing fact that the various time limits of the segment mean-square displacement of polymers in some cases perfectly reproduce predictions of the tube/reptation model whereas the reorientation dynamics suggests strongly deviating power laws. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Quasi-elastic (QENS) and inelastic neutron scattering (INS) on hexamethylbenzene

    NASA Astrophysics Data System (ADS)

    Krawczyk, J.; Mayer, J.; Natkaniec, I.; Nowina Konopka, M.; Pawlukojć; Steinsvoll, O.; Janik, J. A.

    2005-05-01

    The Quasi-elastic Neutron scattering (QENS) spectra of polycrystalline hexamethylbenzene (HMB) were measured for temperatures from 10 K to room temperature (phase III and phase II) for momentum transfer 1.9 Å -1. The Inelastic Neutron scattering (INS) and QENS spectra for momentum transfer 0.5-2.9 Å -1 were measured at T=20, 100 and 130 K for energy transfer up to 200 meV. The low-resolution diffraction patterns, used as the phase indicator, were also obtained. In the phase III (below 117 K), we see practically no quasi-elastic broadening. In phase II, the broadening changes with the temperature are in good agreement with the Arrhenius law. The estimated activation barrier to reorientation is 6 kJ/mol. The fitted mean time between instantaneous 120° jumps of CH 3 groups changes from 10 -11 s at T=130 K to 2×10 -13 s at room temperature. On the basis of EISF versus momentum transfer dependency it is hardly possible to decide what is the geometry of the reorientation. Both reorientation of the CH 3 groups around the three-fold symmetry axis and reorientation of the whole molecule around the six-fold symmetry axis of the benzene ring could describe our results, the former being more probable. The measured INS spectra are compared with the quantum chemical ab initio calculations performed for an isolated HMB molecule.

  14. Spinning in the Scanner: Neural Correlates of Virtual Reorientation

    ERIC Educational Resources Information Center

    Sutton, Jennifer E.; Joanisse, Marc F.; Newcombe, Nora S.

    2010-01-01

    Recent studies have used spatial reorientation task paradigms to identify underlying cognitive mechanisms of navigation in children, adults, and a range of animal species. Despite broad interest in this task across disciplines, little is known about the brain bases of reorientation. We used functional magnetic resonance imaging to examine neural…

  15. In situ neutron diffraction study of twin reorientation and pseudoplastic strain in Ni-Mn-Ga single crystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stoica, Alexandru Dan

    2011-01-01

    Twin variant reorientation in single-crystal Ni-Mn-Ga during quasi-static mechanical compression was studied using in situ neutron diffraction. The volume fraction of reoriented twin variants for different stress amplitudes were obtained from the changes in integrated intensities of high-order neutron diffraction peaks. It is shown that, during compressive loading, {approx}85% of the twins were reoriented parallel to the loading direction resulting in a maximum pseudoplasticstrain of {approx}5.5%, which is in agreement with measured macroscopic strain.

  16. Twin-variant reorientation strain in Ni-Mn-Ga single crystal during quasi-static mechanical compression

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pramanick, Abhijit; An, Ke; Stoica, Alexandru Dan

    2011-01-01

    Twin variant reorientation in single crystal Ni-Mn-Ga during quasi-static mechanical compression was studied using in-situ neutron diffraction. The volume fraction of reoriented twin variants for different stress amplitudes were obtained from the changes in integrated intensities of high-order neutron diffraction peaks. It is shown that during compressive loading, ~85% of the twins were reoriented parallel to the loading direction resulting in a maximum macroscopic strain of ~5.5%, which is in agreement with measured macroscopic strain.

  17. Sudden jump in VAP spurs QI to cut rate to near zero.

    PubMed

    2005-07-01

    New device allows staff to brush ventilated patients' teeth three times a day. Just-in-time training for teams includes reorientation to cause/effect diagrams, control charts. Benchmarking data helps earn trust, business support of high-volume payer.

  18. Thermal stratification hinders gyrotactic micro-organism rising in free-surface turbulence

    NASA Astrophysics Data System (ADS)

    Lovecchio, Salvatore; Zonta, Francesco; Marchioli, Cristian; Soldati, Alfredo

    2017-05-01

    Thermal stratification in water bodies influences the exchange of heat, momentum, and chemical species across the air-water interface by modifying the sub-surface turbulence characteristics. Turbulence modifications may in turn prevent small motile algae (phytoplankton, in particular) from reaching the heated surface. We examine how different regimes of stable thermal stratification affect the motion of these microscopic organisms (modelled as gyrotactic self-propelling cells) in a free-surface turbulent channel flow. This archetypal setup mimics an environmentally plausible situation that can be found in lakes and oceans. Results from direct numerical simulations of turbulence coupled with Lagrangian tracking reveal that rising of bottom-heavy self-propelling cells depends strongly on the strength of stratification, especially near the thermocline where high temperature and velocity gradients occur: Here hydrodynamic shear may disrupt directional cell motility and hamper near-surface accumulation. For all gyrotactic re-orientation times considered in this study (spanning two orders of magnitude), we observe a reduction of the cell rising speed and temporary confinement under the thermocline: If re-orientation is fast, cells eventually trespass the thermocline within the simulated time span; if re-orientation is slow, confinement lasts much longer because cells align in the streamwise direction and their vertical swimming is practically annihilated.

  19. Engineering fibrin-based tissue constructs from myofibroblasts and application of constraints and strain to induce cell and collagen reorganization.

    PubMed

    de Jonge, Nicky; Baaijens, Frank P T; Bouten, Carlijn V C

    2013-10-28

    Collagen content and organization in developing collagenous tissues can be influenced by local tissue strains and tissue constraint. Tissue engineers aim to use these principles to create tissues with predefined collagen architectures. A full understanding of the exact underlying processes of collagen remodeling to control the final tissue architecture, however, is lacking. In particular, little is known about the (re)orientation of collagen fibers in response to changes in tissue mechanical loading conditions. We developed an in vitro model system, consisting of biaxially-constrained myofibroblast-seeded fibrin constructs, to further elucidate collagen (re)orientation in response to i) reverting biaxial to uniaxial static loading conditions and ii) cyclic uniaxial loading of the biaxially-constrained constructs before and after a change in loading direction, with use of the Flexcell FX4000T loading device. Time-lapse confocal imaging is used to visualize collagen (re)orientation in a nondestructive manner. Cell and collagen organization in the constructs can be visualized in real-time, and an internal reference system allows us to relocate cells and collagen structures for time-lapse analysis. Various aspects of the model system can be adjusted, like cell source or use of healthy and diseased cells. Additives can be used to further elucidate mechanisms underlying collagen remodeling, by for example adding MMPs or blocking integrins. Shape and size of the construct can be easily adapted to specific needs, resulting in a highly tunable model system to study cell and collagen (re)organization.

  20. Is Language Necessary for Human Spatial Reorientation? Reconsidering Evidence from Dual Task Paradigms

    ERIC Educational Resources Information Center

    Ratliff, Kristin R.; Newcombe, Nora S.

    2008-01-01

    Being able to reorient to the spatial environment after disorientation is a basic adaptive challenge. There is clear evidence that reorientation uses geometric information about the shape of the surrounding space. However, there has been controversy concerning whether use of geometry is a modular function, and whether use of features is dependent…

  1. An analytical study of reduced-gravity liquid reorientation using a simplified marker and cell technique

    NASA Technical Reports Server (NTRS)

    Betts, W. S., Jr.

    1972-01-01

    A computer program called HOPI was developed to predict reorientation flow dynamics, wherein liquids move from one end of a closed, partially filled, rigid container to the other end under the influence of container acceleration. The program uses the simplified marker and cell numerical technique and, using explicit finite-differencing, solves the Navier-Stokes equations for an incompressible viscous fluid. The effects of turbulence are also simulated in the program. HOPI can consider curved as well as straight walled boundaries. Both free-surface and confined flows can be calculated. The program was used to simulate five liquid reorientation cases. Three of these cases simulated actual NASA LeRC drop tower test conditions while two cases simulated full-scale Centaur tank conditions. It was concluded that while HOPI can be used to analytically determine the fluid motion in a typical settling problem, there is a current need to optimize HOPI. This includes both reducing the computer usage time and also reducing the core storage required for a given size problem.

  2. Human sperm pattern of movement during chemotactic re-orientation towards a progesterone source

    PubMed Central

    Blengini, Cecilia Soledad; Teves, Maria Eugenia; Uñates, Diego Rafael; Guidobaldi, Héctor Alejandro; Gatica, Laura Virginia; Giojalas, Laura Cecilia

    2011-01-01

    Human spermatozoa may chemotactically find out the egg by following an increasing gradient of attractant molecules. Although human spermatozoa have been observed to show several of the physiological characteristics of chemotaxis, the chemotactic pattern of movement has not been easy to describe. However, it is apparent that chemotactic cells may be identified while returning to the attractant source. This study characterizes the pattern of movement of human spermatozoa during chemotactic re-orientation towards a progesterone source, which is a physiological attractant candidate. By means of videomicroscopy and image analysis, a chemotactic pattern of movement was identified as the spermatozoon returned towards the source of a chemotactic concentration of progesterone (10 pmol l−1). First, as a continuation of its original path, the spermatozoon swims away from the progesterone source with linear movement and then turns back with a transitional movement that can be characterized by an increased velocity and decreased linearity. This sperm behaviour may help the spermatozoon to re-orient itself towards a progesterone source and may be used to identify the few cells that are undergoing chemotaxis at a given time. PMID:21765441

  3. Microtubule bundling plays a role in ethylene-mediated cortical microtubule reorientation in etiolated Arabidopsis hypocotyls.

    PubMed

    Ma, Qianqian; Sun, Jingbo; Mao, Tonglin

    2016-05-15

    The gaseous hormone ethylene is known to regulate plant growth under etiolated conditions (the 'triple response'). Although organization of cortical microtubules is essential for cell elongation, the underlying mechanisms that regulate microtubule organization by hormone signaling, including ethylene, are ambiguous. In the present study, we demonstrate that ethylene signaling participates in regulation of cortical microtubule reorientation. In particular, regulation of microtubule bundling is important for this process in etiolated hypocotyls. Time-lapse analysis indicated that selective stabilization of microtubule-bundling structures formed in various arrays is related to ethylene-mediated microtubule orientation. Bundling events and bundle growth lifetimes were significantly increased in oblique and longitudinal arrays, but decreased in transverse arrays in wild-type cells in response to ethylene. However, the effects of ethylene on microtubule bundling were partially suppressed in a microtubule-bundling protein WDL5 knockout mutant (wdl5-1). This study suggests that modulation of microtubule bundles that have formed in certain orientations plays a role in reorienting microtubule arrays in response to ethylene-mediated etiolated hypocotyl cell elongation. © 2016. Published by The Company of Biologists Ltd.

  4. Diffusion and spectroscopy of water and lipids in fully hydrated dimyristoylphosphatidylcholine bilayer membranes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, J.; Martí, J., E-mail: jordi.marti@upc.edu; Calero, C.

    2014-03-14

    Microscopic structure and dynamics of water and lipids in a fully hydrated dimyristoylphosphatidylcholine phospholipid lipid bilayer membrane in the liquid-crystalline phase have been analyzed with all-atom molecular dynamics simulations based on the recently parameterized CHARMM36 force field. The diffusive dynamics of the membrane lipids and of its hydration water, their reorientational motions as well as their corresponding spectral densities, related to the absorption of radiation, have been considered for the first time using the present force field. In addition, structural properties such as density and pressure profiles, a deuterium-order parameter, surface tension, and the extent of water penetration in themore » membrane have been analyzed. Molecular self-diffusion, reorientational motions, and spectral densities of atomic species reveal a variety of time scales playing a role in membrane dynamics. The mechanisms of lipid motion strongly depend on the time scale considered, from fast ballistic translation at the scale of picoseconds (effective diffusion coefficients of the order of 10{sup −5} cm{sup 2}/s) to diffusive flow of a few lipids forming nanodomains at the scale of hundreds of nanoseconds (diffusion coefficients of the order of 10{sup −8} cm{sup 2}/s). In the intermediate regime of sub-diffusion, collisions with nearest neighbors prevent the lipids to achieve full diffusion. Lipid reorientations along selected directions agree well with reported nuclear magnetic resonance data and indicate two different time scales, one about 1 ns and a second one in the range of 2–8 ns. We associated the two time scales of reorientational motions with angular distributions of selected vectors. Calculated spectral densities corresponding to lipid and water reveal an overall good qualitative agreement with Fourier transform infrared spectroscopy experiments. Our simulations indicate a blue-shift of the low frequency spectral bands of hydration water as a result of its interaction with lipids. We have thoroughly analyzed the physical meaning of all spectral features from lipid atomic sites and correlated them with experimental data. Our findings include a “wagging of the tails” frequency around 30 cm{sup −1}, which essentially corresponds to motions of the tail-group along the instantaneous plane formed by the two lipid tails, i.e., in-plane oscillations are clearly of bigger importance than those along the normal-to-the plane direction.« less

  5. Dual reorientation relaxation routes of water molecules in oxyanion’s hydration shell: A molecular geometry perspective

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xie, Wen Jun; Yang, Yi Isaac; Gao, Yi Qin, E-mail: gaoyq@pku.edu.cn

    2015-12-14

    In this study, we examine how complex ions such as oxyanions influence the dynamic properties of water and whether differences exist between simple halide anions and oxyanions. Nitrate anion is taken as an example to investigate the hydration properties of oxyanions. Reorientation relaxation of its hydration water can occur through two different routes: water can either break its hydrogen bond with the nitrate to form one with another water or switch between two oxygen atoms of the same nitrate. The latter molecular mechanism increases the residence time of oxyanion’s hydration water and thus nitrate anion slows down the translational motionmore » of neighbouring water. But it is also a “structure breaker” in that it accelerates the reorientation relaxation of hydration water. Such a result illustrates that differences do exist between the hydration of oxyanions and simple halide anions as a result of different molecular geometries. Furthermore, the rotation of the nitrate solute is coupled with the hydrogen bond rearrangement of its hydration water. The nitrate anion can either tilt along the axis perpendicularly to the plane or rotate in the plane. We find that the two reorientation relaxation routes of the hydration water lead to different relaxation dynamics in each of the two above movements of the nitrate solute. The current study suggests that molecular geometry could play an important role in solute hydration and dynamics.« less

  6. Geometry Three Ways: An fMRI Investigation of Geometric Information Processing during Reorientation

    ERIC Educational Resources Information Center

    Sutton, Jennifer E.; Twyman, Alexandra D.; Joanisse, Marc F.; Newcombe, Nora S.

    2012-01-01

    The geometry formed by the walls of a room is known to be a potent cue in reorientation, yet little is known about the use of geometric information gleaned from other contexts. We used functional magnetic resonance imaging to examine neural activity in adults while reorienting in 3 different environments: the typical rectangular walled room, a…

  7. Reorienting with terrain slope and landmarks.

    PubMed

    Nardi, Daniele; Newcombe, Nora S; Shipley, Thomas F

    2013-02-01

    Orientation (or reorientation) is the first step in navigation, because establishing a spatial frame of reference is essential for a sense of location and heading direction. Recent research on nonhuman animals has revealed that the vertical component of an environment provides an important source of spatial information, in both terrestrial and aquatic settings. Nonetheless, humans show large individual and sex differences in the ability to use terrain slope for reorientation. To understand why some participants--mainly women--exhibit a difficulty with slope, we tested reorientation in a richer environment than had been used previously, including both a tilted floor and a set of distinct objects that could be used as landmarks. This environment allowed for the use of two different strategies for solving the task, one based on directional cues (slope gradient) and one based on positional cues (landmarks). Overall, rather than using both cues, participants tended to focus on just one. Although men and women did not differ significantly in their encoding of or reliance on the two strategies, men showed greater confidence in solving the reorientation task. These facts suggest that one possible cause of the female difficulty with slope might be a generally lower spatial confidence during reorientation.

  8. Molecular dynamics of 17α- and 21-hydroxy progesterone studied by NMR. Relation between molecule conformation and height of the barrier for methyl group reorientations in steroid compounds

    NASA Astrophysics Data System (ADS)

    Szyczewski, A.; Hołderna-Natkaniec, K.

    2005-01-01

    For the two steroid compounds 17αOH-progesterone and 21OH-progesterone, the activation energies of reorientations of the methyl groups have been determined. Their values together with results of the quantum chemical calculations permitted establishment of the sequence of the onset of the methyl group reorientations about the three-fold symmetry axis of the C-C bond. On the basis of the asymmetry parameters, the conformations of the hitherto studied pregnane derivatives and testosterone have been determined. It has been found that the conformation of ring A has dominant effect on the activation energies of the reorientation of C(19)H 3. The reorientation of the methyl group C(18)H 3 significantly depends on the conformation of the side chain 17β (torsional angle C(13)-C(17)-C(20)-O(20)) and the distance between C18 and O20. The study has proved that the 1H NMR method in combination with the quantum chemistry calculations and inelastic incoherent neutron scattering (IINS) are effective for prediction of the sequence of the methyl group reorientations about the three-fold symmetry axis.

  9. Switching of bacterial adhesion to a glycosylated surface by reversible reorientation of the carbohydrate ligand.

    PubMed

    Weber, Theresa; Chandrasekaran, Vijayanand; Stamer, Insa; Thygesen, Mikkel B; Terfort, Andreas; Lindhorst, Thisbe K

    2014-12-22

    The surface recognition in many biological systems is guided by the interaction of carbohydrate-specific proteins (lectins) with carbohydrate epitopes (ligands) located within the unordered glycoconjugate layer (glycocalyx) of cells. Thus, for recognition, the respective ligand has to reorient for a successful matching event. Herein, we present for the first time a model system, in which only the orientation of the ligand is altered in a controlled manner without changing the recognition quality of the ligand itself. The key for this orientational control is the embedding into an interfacial system and the use of a photoswitchable mechanical joint, such as azobenzene. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. An analytical study of reduced-gravity propellant settling

    NASA Technical Reports Server (NTRS)

    Bradshaw, R. D.; Kramer, J. L.; Masica, W. J.

    1974-01-01

    Full-scale propellant reorientation flow dynamics for the Centaur D-1T fuel tank were analyzed. A computer code using the simplified marker and cell technique was modified to include the capability for a variable-grid mesh configuration. Use of smaller cells near the boundary, near baffles, and in corners provides improved flow resolution. Two drop tower model cases were simulated to verify program validity: one case without baffles, the other with baffles and geometry identical to Centaur D-1T. Flow phenomena using the new code successfully modeled drop tower data. Baffles are a positive factor in the settling flow. Two full-scale Centaur D-1T cases were simulated using parameters based on the Titan/Centaur proof flight. These flow simulations indicated the time to clear the vent area and an indication of time to orient and collect the propellant. The results further indicated the complexity of the reorientation flow and the long time period required for settling.

  11. Real-Time Observation of Organic Cation Reorientation in Methylammonium Lead Iodide Perovskites.

    PubMed

    Bakulin, Artem A; Selig, Oleg; Bakker, Huib J; Rezus, Yves L A; Müller, Christian; Glaser, Tobias; Lovrincic, Robert; Sun, Zhenhua; Chen, Zhuoying; Walsh, Aron; Frost, Jarvist M; Jansen, Thomas L C

    2015-09-17

    The introduction of a mobile and polarized organic moiety as a cation in 3D lead-iodide perovskites brings fascinating optoelectronic properties to these materials. The extent and the time scales of the orientational mobility of the organic cation and the molecular mechanism behind its motion remain unclear, with different experimental and computational approaches providing very different qualitative and quantitative description of the molecular dynamics. Here we use ultrafast 2D vibrational spectroscopy of methylammonium (MA) lead iodide to directly resolve the rotation of the organic cations within the MAPbI3 lattice. Our results reveal two characteristic time constants of motion. Using ab initio molecular dynamics simulations, we identify these as a fast (∼300 fs) "wobbling-in-a-cone" motion around the crystal axis and a relatively slow (∼3 ps) jump-like reorientation of the molecular dipole with respect to the iodide lattice. The observed dynamics are essential for understanding the electronic properties of perovskite materials.

  12. Capturing the effect of [PF3(C2F5)3]-vs. [PF6]-, flexible anion vs. rigid, and scaled charge vs. unit on the transport properties of [bmim]+-based ionic liquids: a comparative MD study.

    PubMed

    Kowsari, Mohammad H; Ebrahimi, Soraya

    2018-05-16

    Comprehensive molecular dynamics simulations are performed to study the average single-particle dynamics and the transport properties of 1-butyl-3-methylimidazolium hexafluorophosphate, [bmim][PF6], and 1-butyl-3-methylimidazolium tris(pentafluoroethyl)trifluorophosphate, [bmim][FAP], ionic liquids (ILs) at 400 K. We applied one of the most widely used nonpolarizable all-atom force fields for ILs, both with the original unit (±1) charges on each ion and with the partial charges uniformly scaled to 80-85%, taking into account the average polarizability and tracing the experimentally compatible transport properties. In all simulations, [bmim]+ was considered to be flexible, while the effect of a flexible vs. rigid structure of the anions and the effect of two applied charge sets on the calculated properties were separately investigated in detail. The simulation results showed that replacing [PF6]- with [FAP]-, considering anion flexibility, and applying the charge-scaled model significantly enhanced the ionic self-diffusion, ionic conductivity, inverse viscosity, and hyper anion preference (HAP). Both of the calculated self-diffusion coefficients from the long-time linear slope of the mean-square displacement (MSD) and from the integration of the velocity autocorrelation function (VACF) for the centers of mass of the ions were used for evaluation of the ionic transference number, HAP, ideal Nernst-Einstein ionic conductivity (σNE), and the Stokes-Einstein viscosity. In addition, for quantification of the degree of complicated ionic association (known as the Nernst-Einstein deviation parameter, Δ) and ionicity phenomena in the two studied ILs, the ionic conductivity was determined more rigorously by the Green-Kubo integral of the electric-current autocorrelation function (ECACF), and then the σGK/σNE ratio was evaluated. It was found that the correlated motion of the (cationanion) neighbors in [bmim][FAP] is smaller than in [bmim][PF6]. The relaxation times of the normalized reorientational autocorrelation functions were computed to gain a deep, molecular-level insight into the rotational motion of the ions. The geometric shape of the ion is a key factor in determining its reorientational dynamics. [bmim]+ shows faster translational and slower rotational dynamics in contrast to [PF6]-.

  13. Reorientation of rotating fluid in microgravity environment with and without gravity jitters

    NASA Technical Reports Server (NTRS)

    Hung, R. J.; Lee, C. C.; Shyu, K. L.

    1990-01-01

    In a spacecraft design, the requirements of settled propellant are different for tank pressurization, engine restart, venting, or propellant transfer. The requirement to settle or to position liquid fuel over the outlet end of the spacecraft propellant tank prior main engine restart poses a microgravity fluid behavior problem. In this paper, the dynamical behavior of liquid propellant, fluid reorientation, and propellant resettling have been carried out through the execution of supercomputer CRAY X-MP to simulate the fluid management in a microgravity environment. Results show that the resettlement of fluid can be accomplished more efficiently for fluid in rotating tank than in nonrotating tank, and also better performance for gravity jitters imposed on fluid settlement than without gravity jitters based on the amount of time needed to carry out resettlement period of time between the initiation and termination of geysering.

  14. Molecular dynamics of solid cortisol studied by NMR

    NASA Astrophysics Data System (ADS)

    Andrew, E. R.

    Polycrystalline cortisol (hydrocortisone; 11β,17α,21-trihydroxy-4-preg- nene-3,20-dione; C21H30O5) has been investigated by continuous and pulse proton NMR methods between 78 and 400 K at Larmor frequencies of 7, 25 and 60 MHz. A reduced value of second moment was found above 90 K and is ascribed to reorientation of two methyl groups. A single asymmetric minimum was found in the temperature dependence of the spin-lattice relaxation times and this also is attributed to reorientation of two methyl groups. The asymmetry suggests an asymmetric distribution of correlation times of the motion. Using the Cole-Davidson distribution, the best computer fit yields the following parameters characterizing the motion: Ea = 11ṡ8 ± 0ṡ1 kJ mol-1, τ0 = 4ṡ6 ± 0ṡ4) x 10-13s, distribution parameter δ = 0ṡ62.

  15. Coupled jump rotational dynamics in aqueous nitrate solutions.

    PubMed

    Banerjee, Puja; Yashonath, Subramanian; Bagchi, Biman

    2016-12-21

    A nitrate ion (NO 3 - ) with its trigonal planar geometry and charges distributed among nitrogen and oxygen atoms can couple to the extensive hydrogen bond network of water to give rise to unique dynamical characteristics. We carry out detailed atomistic simulations and theoretical analyses to investigate these aspects and report certain interesting findings. We find that the nitrate ions in aqueous potassium nitrate solution exhibit large amplitude rotational jump motions that are coupled to the hydrogen bond rearrangement dynamics of the surrounding water molecules. The jump motion of nitrate ions bears certain similarities to the Laage-Hynes mechanism of rotational jump motions of tagged water molecules in neat liquid water. We perform a detailed atomic-level investigation of hydrogen bond rearrangement dynamics of water in aqueous KNO 3 solution to unearth two distinct mechanisms of hydrogen bond exchange that are instrumental to promote these jump motions of nitrate ions. As observed in an earlier study by Xie et al., in the first mechanism, after breaking a hydrogen bond with nitrate ion, water forms a new hydrogen bond with a water molecule, whereas the second mechanism involves just a switching of hydrogen bond between the two oxygen atoms of the same nitrate ion (W. J. Xie et al., J. Chem. Phys. 143, 224504 (2015)). The magnitude as well as nature of the reorientational jump of nitrate ion for the two mechanisms is different. In the first mechanism, nitrate ion predominantly undergoes out-of-plane rotation, while in the second mechanism, in-plane reorientation of NO 3 - is favourable. These have been deduced by computing the torque on the nitrate ion during the hydrogen bond switching event. We have defined and computed the time correlation function for coupled reorientational jump of nitrate and water and obtained the associated relaxation time which is also different for the two mechanisms. These results provide insight into the relation between the coupled reorientational jump dynamics of solute and solvent molecules.

  16. Predicting Retrograde Autobiographical Memory Changes Following Electroconvulsive Therapy: Relationships between Individual, Treatment, and Early Clinical Factors.

    PubMed

    Martin, Donel M; Gálvez, Verònica; Loo, Colleen K

    2015-06-19

    Loss of personal memories experienced prior to receiving electroconvulsive therapy is common and distressing and in some patients can persist for many months following treatment. Improved understanding of the relationships between individual patient factors, electroconvulsive therapy treatment factors, and clinical indicators measured early in the electroconvulsive therapy course may help clinicians minimize these side effects through better management of the electroconvulsive therapy treatment approach. In this study we examined the associations between the above factors for predicting retrograde autobiographical memory changes following electroconvulsive therapy. Seventy-four depressed participants with major depressive disorder were administered electroconvulsive therapy 3 times per week using either a right unilateral or bitemporal electrode placement and brief or ultrabrief pulse width. Verbal fluency and retrograde autobiographical memory (assessed using the Columbia Autobiographical Memory Interview - Short Form) were tested at baseline and after the last electroconvulsive therapy treatment. Time to reorientation was measured immediately following the third and sixth electroconvulsive therapy treatments. Results confirmed the utility of measuring time to reorientation early during the electroconvulsive therapy treatment course as a predictor of greater retrograde amnesia and the importance of assessing baseline cognitive status for identifying patients at greater risk for developing later side effects. With increased number of electroconvulsive therapy treatments, older age was associated with increased time to reorientation. Consistency of verbal fluency performance was moderately correlated with change in Columbia Autobiographical Memory Interview - Short Form scores following right unilateral electroconvulsive therapy. Electroconvulsive therapy treatment techniques associated with lesser cognitive side effects should be particularly considered for patients with lower baseline cognitive status or older age. © The Author 2015. Published by Oxford University Press on behalf of CINP.

  17. Predicting Retrograde Autobiographical Memory Changes Following Electroconvulsive Therapy: Relationships between Individual, Treatment, and Early Clinical Factors

    PubMed Central

    Gálvez, Verònica; Loo, Colleen K.

    2015-01-01

    Background: Loss of personal memories experienced prior to receiving electroconvulsive therapy is common and distressing and in some patients can persist for many months following treatment. Improved understanding of the relationships between individual patient factors, electroconvulsive therapy treatment factors, and clinical indicators measured early in the electroconvulsive therapy course may help clinicians minimize these side effects through better management of the electroconvulsive therapy treatment approach. In this study we examined the associations between the above factors for predicting retrograde autobiographical memory changes following electroconvulsive therapy. Methods: Seventy-four depressed participants with major depressive disorder were administered electroconvulsive therapy 3 times per week using either a right unilateral or bitemporal electrode placement and brief or ultrabrief pulse width. Verbal fluency and retrograde autobiographical memory (assessed using the Columbia Autobiographical Memory Interview – Short Form) were tested at baseline and after the last electroconvulsive therapy treatment. Time to reorientation was measured immediately following the third and sixth electroconvulsive therapy treatments. Results: Results confirmed the utility of measuring time to reorientation early during the electroconvulsive therapy treatment course as a predictor of greater retrograde amnesia and the importance of assessing baseline cognitive status for identifying patients at greater risk for developing later side effects. With increased number of electroconvulsive therapy treatments, older age was associated with increased time to reorientation. Consistency of verbal fluency performance was moderately correlated with change in Columbia Autobiographical Memory Interview – Short Form scores following right unilateral electroconvulsive therapy. Conclusions: Electroconvulsive therapy treatment techniques associated with lesser cognitive side effects should be particularly considered for patients with lower baseline cognitive status or older age. PMID:26091817

  18. Children's use of geometry for reorientation.

    PubMed

    Lee, Sang Ah; Spelke, Elizabeth S

    2008-09-01

    Research on navigation has shown that humans and laboratory animals recover their sense of orientation primarily by detecting geometric properties of large-scale surface layouts (e.g. room shape), but the reasons for the primacy of layout geometry have not been clarified. In four experiments, we tested whether 4-year-old children reorient by the geometry of extended wall-like surfaces because such surfaces are large and perceived as stable, because they serve as barriers to vision or to locomotion, or because they form a single, connected geometric figure. Disoriented children successfully reoriented by the shape of an arena formed by surfaces that were short enough to see and step over. In contrast, children failed to reorient by the shape of an arena defined by large and stable columns or by connected lines on the floor. We conclude that preschool children's reorientation is not guided by the functional relevance of the immediate environmental properties, but rather by a specific sensitivity to the geometric properties of the extended three-dimensional surface layout.

  19. Rotational-path decomposition based recursive planning for spacecraft attitude reorientation

    NASA Astrophysics Data System (ADS)

    Xu, Rui; Wang, Hui; Xu, Wenming; Cui, Pingyuan; Zhu, Shengying

    2018-02-01

    The spacecraft reorientation is a common task in many space missions. With multiple pointing constraints, it is greatly difficult to solve the constrained spacecraft reorientation planning problem. To deal with this problem, an efficient rotational-path decomposition based recursive planning (RDRP) method is proposed in this paper. The uniform pointing-constraint-ignored attitude rotation planning process is designed to solve all rotations without considering pointing constraints. Then the whole path is checked node by node. If any pointing constraint is violated, the nearest critical increment approach will be used to generate feasible alternative nodes in the process of rotational-path decomposition. As the planning path of each subdivision may still violate pointing constraints, multiple decomposition is needed and the reorientation planning is designed as a recursive manner. Simulation results demonstrate the effectiveness of the proposed method. The proposed method has been successfully applied in two SPARK microsatellites to solve onboard constrained attitude reorientation planning problem, which were developed by the Shanghai Engineering Center for Microsatellites and launched on 22 December 2016.

  20. Young Children's Use of Features to Reorient Is More than Just Associative: Further Evidence against a Modular View of Spatial Processing

    ERIC Educational Resources Information Center

    Newcombe, Nora S.; Ratliff, Kristin R.; Shallcross, Wendy L.; Twyman, Alexandra D.

    2010-01-01

    Proponents of a geometric module have argued that instances of young children's use of features as well as geometry to reorient can be explained by a two-stage process. In this model, only the first stage is a true reorientation, accomplished by using geometric information alone; features are considered in a second stage using association (Lee,…

  1. Mass imprisonment and the life course revisited: Cumulative years spent imprisoned and marked for working-age black and white men.

    PubMed

    Patterson, Evelyn J; Wildeman, Christopher

    2015-09-01

    Over the last 40 years, imprisonment has become a common stage in the life-course for low-skilled and minority men, with implications not only for inequality among adult men but also for inequality more broadly. Unfortunately, all research documenting how increases in imprisonment have transformed the life-course of poor, minority men has neglected to estimate how much time black and white men on average spend imprisoned or marked as an ex-prisoner. In this article, we fill this gap by using multistate life tables to estimate what share of their working lives (18-64) black and white men will spend imprisoned and marked as ex-prisoners. Our estimates imply that white men spend on average 0.33 years of their working lives imprisoned and 2.31 years marked, while black men spend on average 1.79 years of their working lives imprisoned and 11.14 years marked. This implies that black men spend on average one-third of their working lives either imprisoned or having been freed but marked by the penal system. For the 32.2% of black men who ever experience imprisonment (Bonczar, 2003), moreover, these estimates imply that they spend on average 5.56 years imprisoned, corresponding to 13.4% of their working lives. Taken together, these findings imply a dramatic reorientation of the life course for black men, as one-third of the black male population will spend one-seventh of their working life in prison. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Europium III binding and the reorientation of magnetically aligned bicelles: insights from deuterium NMR spectroscopy.

    PubMed Central

    Crowell, K J; Macdonald, P M

    2001-01-01

    Solid-state deuterium ((2)H) NMR spectroscopy was used to study the reorientation of magnetically ordered bicelles in the presence of the paramagnetic lanthanide Eu(3+). Bicelles were composed of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) plus 1,2-dihexanoyl-sn-glycero-3-phosphocholine plus either the anionic lipid 1,2-dimyristoyl-sn-3-phosphoglycerol, or the cationic lipid 1,2-dimyristoyl-3-trimethyl ammonium propane. Alignment of the bicelles in the magnetic field produced (2)H NMR spectra consisting of a pair of quadrupole doublets, one from the alpha-deuterons and one from the beta-deuterons of DMPC-alpha,beta-d(4). Eu(3+) addition induced the appearance of a second set of quadrupole doublets, having approximately twice the quadrupolar splittings of the originals, and growing progressively in intensity with increasing Eu(3+), at the expense of the intensity of the originals. The new resonances were attributed to bicelles having a parallel alignment with respect to the magnetic field, as opposed to the perpendicular alignment preferred in the absence of Eu(3+). Therefore, the equilibrium degree and kinetics of reorientation could be evaluated from the (2)H NMR spectra. For more cationic initial surface charges, higher amounts of added Eu(3+) were required to induce a given degree of reorientation. However, the equilibrium degree of bicellar reorientation was found to depend solely on the amount of bound Eu(3+), regardless of the bicelle composition. The kinetics of reorientation were a function of lipid concentration. At high lipid concentration, a single fast rate of reorientation (minutes) described the approach to the equilibrium degree of orientation. At lower lipid concentrations, two rates processes were discernible: one fast (minutes) and one slow (hours). The data indicate, therefore, that bicelle reorientation is a phase transition made critical by bicelle-bicelle interactions. PMID:11423411

  3. Paleomagnetic Reorientation of Structural Elements in Drill Cores: an example from Tolhuaca Geothermal Field

    NASA Astrophysics Data System (ADS)

    Perez-Flores, P.; Veloso, E. E.; Cembrano, J. M.; Sánchez, P.; Iriarte, S.; Lohmar, S.

    2013-12-01

    Reorientation of mesoscopic faults, veins and fractures recovered from drilling is critical to construct reliable structural models that can account for their architecture and deformation regime. However, oriented cores are expensive and time consuming to drill. Some techniques achieve reorientation by introducing tools into the borehole. Problems arise when boreholes are unstable or collapse. One alternative technique allowing reorientation is to obtain reliable paleomagnetic vectors to reorient each core piece after drilling. Here, we present stable and reliable remnant magnetic vectors calculated from the Tol-1 core to analyze the geometry of the fracture network and its relationship to regional tectonic. Tol-1 core is a vertical, 1073 m deep geothermal well, drilled at the Tolhuaca Geothermal Field in the Southern Volcanic Zone of the Andes by MRP Geothermal Chile Ltda (formerly GGE Chile SpA) in 2009. The core consists of basaltic/andesitic volcanic rocks with subordinate pyroclastic/volcaniclastic units, with probable Pleistocene age. Fault planes with slickenlines and mineral fiber kinematic indicators are common in the upper 700 m of the core. Calcite, quartz and calcite-quartz veins are recognized along of entire core, whereas epidote-quartz and calcite-epidote veins occur in the last 350 m, minor chlorite, anhydrite and clay-minerals are present. Orientations of structural features in the core were measured with a goniometer using the core's axis and a false north for each piece; hence, orientation data has a false strike but a real dip. To achieve total reorientation of the pieces, we collected 200 standard-size paleomagnetic specimens, ensuring that at least four of them were recovered from continuous pieces. Thermal (up to 700°C) and alternating field demagnetization (up to 90mT on steps of 2mT) methods were used to isolate a stable remnant magnetization (RM) vector, and each technique yielded similar results. RM vectors were recovered between 0 to 25mT, and between 0 to 625°C. The declination of RM vectors was used to bring pieces to a common anchor orientation calculated through the Geocentric Axial Dipole Model (GAD). The paleomagnetic technique proved to be reliable to reorient the Tol-1 core. Structural analyses along the core show N50-60E-striking preferential vein orientation. In addition, N40-50E- and N60-70W-striking preferential fault orientations were identified. Kinematic analysis of fault-slip data shows a N60E-striking bulk fault plane solution with normal strain regime. The veins and faults orientation show strain axes compatible with published regional stress field (σmax N238E).

  4. ORNL Interim Progress Report on Hydride Reorientation CIRFT Tests

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Jy-An John; Yan, Yong; Wang, Hong

    A systematic study of H. B. Robinson (HBR) high burnup spent nuclear fuel (SNF) vibration integrity was performed in Phase I project under simulated transportation environments, using the Cyclic Integrated Reversible-Bending Fatigue Tester (CIRFT) hot cell testing technology developed at Oak Ridge National Laboratory in 2013–14. The data analysis on the as-irradiated HBR SNF rods demonstrated that the load amplitude is the dominant factor that controls the fatigue life of bending rods. However, previous studies have shown that the hydrogen content and hydride morphology has an important effect on zirconium alloy mechanical properties. To address the effect of radial hydridesmore » in SNF rods, in Phase II a test procedure was developed to simulate the effects of elevated temperatures, pressures, and stresses during transfer-drying operations. Pressurized and sealed fuel segments were heated to the target temperature for a preset hold time and slow-cooled at a controlled rate. The procedure was applied to both non-irradiated/prehydrided and high-burnup Zircaloy-4 fueled cladding segments using the Nuclear Regulatory Commission-recommended 400°C maximum temperature limit at various cooling rates. Before testing high-burnup cladding, four out-of-cell tests were conducted to optimize the hydride reorientation (R) test condition with pre-hydride Zircaloy-4 cladding, which has the same geometry as the high burnup fuel samples. Test HR-HBR#1 was conducted at the maximum hoop stress of 145 MPa, at a 400°C maximum temperature and a 5°C/h cooling rate. On the other hand, thermal cycling was performed for tests HR-HBR#2, HR-HBR#3, and HR-HBR#4 to generate more radial hydrides. It is clear that thermal cycling increases the ratio of the radial hydride to circumferential hydrides. The internal pressure also has a significant effect on the radial hydride morphology. This report describes a procedure and experimental results of the four out-of-cell hydride reorientation tests of hydrided Zircaloy-4 cladding, which served as a guideline to prepare in-cell hydride reorientation samples with high burnup HBR fuel segments. This report also provides the Phase II CIRFT test data for the hydride reorientation irradiated samples. The variations in fatigue life are provided in terms of moment, equivalent stress, curvature, and equivalent strain for the tested SNFs. The CIRFT results appear to indicate that hydride reoriented treatment (HRT) have a negative effect on fatigue life, in addition to hydride reorientation effect. For HR4 specimen that had no pressurization procedure applied, the thermal annealing treatment alone showed a negative impact on the fatigue life compared to the HBR rod.« less

  5. Gravitaxis of Euglena gracilis depends only partially on passive buoyancy

    NASA Astrophysics Data System (ADS)

    Richter, Peter R.; Schuster, Martin; Lebert, Michael; Streb, Christine; Häder, Donat-Peter

    In darkness, the unicellular freshwater flagellate Euglena gracilis shows a pronounced negative gravitactic behavior, and the cells swim actively upward in the water column. Up to now it was unclear whether this behavior is based on a passive (physical) alignment mechanism (e.g., buoyancy due to a fore-aft asymmetry of the cell body) or on an active physiological mechanism. A sounding rocket experiment was performed in which the effect of sub-1g-accelerations (0.05, 0.08, 0.12, and 0.2g) on untreated living cells and immobilized (fixation with liquid nitrogen) cells was observed. By means of computerized image analysis the angles of the cells long axis with respect to the acceleration vector were analyzed in order to calculate and compare the reorientation kinetics of the immobilized cells versus that of the controls. In both groups, the reorientation kinetics depended on the dose, but the reorientation of the living cells was about five times faster than that of the immobilized cells. This indicates that in young cells gravitaxis can be explained by a physical mechanism only to a small extend. In older cultures, in which the cells often have a drop shaped cell body, the physical reorientation is considerably faster, and a more pronounced influence of passive alignment caused by fore/aft asymmetry (drag-gravity model) can not be excluded. In addition to these results, Euglena gracilis cells seem to respond very sensitively to small accelerations when they are applied after a longer microgravity period. The data indicate that gravitactic orientation occurred at an acceleration as low as 0.05g.

  6. A reorientation strategy for reducing delirium in the critically ill. Results of an interventional study.

    PubMed

    Colombo, R; Corona, A; Praga, F; Minari, C; Giannotti, C; Castelli, A; Raimondi, F

    2012-09-01

    A wide variability in the approach towards delirium prevention and treatment in the critically ill results from the dearth of prospective randomised studies. We launched a two-stage prospective observational study to assess delirium epidemiology, risk factors and impact on patient outcome, by enrolling all patients admitted to our Intensive Care Unit (ICU) over a year. The first step - from January to June 2008 was the observational phase, whereas the second one from July to December 2008 was interventional. All the patients admitted to our ICU were recruited but those with pre-existing cognitive disorders, dementia, psychosis and disability after stroke were excluded from the data analysis. Delirium assessment was performed according with Confusion Assessment Method for the ICU twice per day after sedation interruption. During phase 2, patients underwent both a re-orientation strategy and environmental, acoustic and visual stimulation. We admitted a total of respectively 170 (I-ph) and 144 patients (II-ph). The delirium occurrence was significantly lower in (II-ph) 22% vs. 35% in (I-ph) (P=0.020). A Cox's Proportional Hazard model found the applied reorientation strategy as the strongest protective predictors of delirium: (HR 0.504, 95% C.I. 0.313-0.890, P=0.034), whereas age (HR 1.034, 95% CI: 1.013-1.056, P=0.001) and sedation with midazolam plus opiate (HR 2.145, 95% CI: 2.247-4.032, P=0.018) were negative predictors. A timely reorientation strategy seems to be correlated with significantly lower occurrence of delirium.

  7. Planar reorientation maneuvers of space multibody systems using internal controls

    NASA Technical Reports Server (NTRS)

    Reyhanoglu, Mahmut; Mcclamroch, N. H.

    1992-01-01

    In this paper a reorientation maneuvering strategy for an interconnection of planar rigid bodies in space is developed. It is assumed that there are no exogeneous torques, and torques generated by joint motors are used as means of control so that the total angular momentum of the multibody system is a constant, assumed to be zero in this paper. The maneuver strategy uses the nonintegrability of the expression for the angular momentum. We demonstrate that large-angle maneuvers can be designed to achieve an arbitrary reorientation of the multibody system with respect to an inertial frame. The theoretical background for carrying out the required maneuvers is briefly summarized. Specifications and computer simulations of a specific reorientation maneuver, and the corresponding control strategies, are described.

  8. Recovery and recrystalization kinetics of cold-worked Zircaloy-4 plate and tubing (LWBR Development Program)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katz, O.M.

    1968-02-01

    Empirical kinetic equations were derived to describe the recovery region between 550 and 1020/sup 0/F for times to 4000 hours for 15 to 78% cold-worked Zircaloy-4 plate and tubing. The properties studied were electrical resistivity and X-ray line sharpening. Recrystallization kinetics were described with sigmoidal curves derived from X-ray intensity and microhardness data. Light, replica, and transmission electron microscopy and selected-area electron diffraction were used to postulate recovery and recrystallization mechanisms. From a structural aspect, the annealing process in cold-worked Zircaloy-4 is visualized as a dislocation climb and annihilation process to the limit allowed by the size of the deformationmore » subcells, a reorientation of the subgrain material into a recrystallization texture, a growth of reoriented cells located in the most highly worked bands, and a consumption of less favorably strained and/or oriented cells by the high-angle boundaries of the reoriented cells. Comparison of 15 and 73% cold-worked tubing showed the activation energy to be less (21 versus 60 kcal/mol) and the subcell size greater (8000A versus 1000A) for the 15% cold-worked material. (NSA 22: 21698)« less

  9. Planned Axial Reorientation Investigation on Sloshsat

    NASA Technical Reports Server (NTRS)

    Chato, David J.

    2000-01-01

    This paper details the design and logic of an experimental investigation to study axial reorientation in low gravity. The Sloshsat free-flyer is described. The planned axial reorientation experiments and test matrixes are presented. Existing analytical tools are discussed. Estimates for settling range from 64 to 1127 seconds. The planned experiments are modelled using computational fluid dynamics. These models show promise in reducing settling estimates and demonstrate the ability of pulsed high thrust settling to emulate lower thrust continuous firing.

  10. Shear alters motility of Escherichia coli

    NASA Astrophysics Data System (ADS)

    Molaei, Mehdi; Jalali, Maryam; Sheng, Jian

    2013-11-01

    Understanding of locomotion of microorganisms in shear flows drew a wide range of interests in microbial related topics such as biological process including pathogenic infection and biophysical interactions like biofilm formation on engineering surfaces. We employed microfluidics and digital holography microscopy to study motility of E. coli in shear flows. We controlled the shear flow in three different shear rates: 0.28 s-1, 2.8 s-1, and 28 s-1 in a straight channel with the depth of 200 μm. Magnified holograms, recorded at 15 fps with a CCD camera over more than 20 minutes, are analyzed to obtain 3D swimming trajectories and subsequently used to extract shear responses of E.coli. Thousands of 3-D bacterial trajectories are tracked. The change of bacteria swimming characteristics including swimming velocity, reorientation, and dispersion coefficient are computed directly for individual trajectory and ensemble averaged over thousands of realizations. The results show that shear suppresses the bacterial dispersions in bulk but promote dispersions near the surface contrary to those in quiescent flow condition. Ongoing analyses are focusing to quantify effect of shear rates on tumbling frequency and reorientation of cell body, and its implication in locating the hydrodynamic mechanisms for shear enhanced angular scattering. NIH, NSF, GoMRI.

  11. 2D-HB-Network at the air-water interface: A structural and dynamical characterization by means of ab initio and classical molecular dynamics simulations

    NASA Astrophysics Data System (ADS)

    Pezzotti, Simone; Serva, Alessandra; Gaigeot, Marie-Pierre

    2018-05-01

    Following our previous work where the existence of a special 2-Dimensional H-Bond (2D-HB)-Network was revealed at the air-water interface [S. Pezzotti et al., J. Phys. Chem. Lett. 8, 3133 (2017)], we provide here a full structural and dynamical characterization of this specific arrangement by means of both Density Functional Theory based and Force Field based molecular dynamics simulations. We show in particular that water at the interface with air reconstructs to maximize H-Bonds formed between interfacial molecules, which leads to the formation of an extended and non-interrupted 2-Dimensional H-Bond structure involving on average ˜90% of water molecules at the interface. We also show that the existence of such an extended structure, composed of H-Bonds all oriented parallel to the surface, constrains the reorientional dynamics of water that is hence slower at the interface than in the bulk. The structure and dynamics of the 2D-HB-Network provide new elements to possibly rationalize several specific properties of the air-water interface, such as water surface tension, anisotropic reorientation of interfacial water under an external field, and proton hopping.

  12. Neural correlates of adolescents' viewing of parents' and peers' emotions: Associations with risk-taking behavior and risky peer affiliations.

    PubMed

    Saxbe, Darby; Del Piero, Larissa; Immordino-Yang, Mary Helen; Kaplan, Jonas; Margolin, Gayla

    2015-01-01

    Social reorientation from parents to same-age peers is normative in adolescence, but the neural correlates of youths' socioemotional processing of parents and peers have not been explored. In the current study, 22 adolescents (average age 16.98) underwent neuroimaging (functional magnetic resonance imaging) while viewing and rating emotions shown in brief video clips featuring themselves, their parents, or an unfamiliar peer. Viewing self vs. other and parents vs. the peer activated regions in the medial prefrontal cortex, replicating prior findings that this area responds to self-relevant stimuli, including familiar and not just similar others. Viewing the peer compared with parents elicited activation in posterior 'mentalizing' structures, the precuneus, posterior cingulate cortex (PCC), bilateral posterior superior temporal sulcus and right temporoparietal junction, as well as the ventral striatum and bilateral amygdala and hippocampus. Relative activations in the PCC and precuneus to the peer vs. the parent were related both to reported risk-taking behavior and to affiliations with more risk-taking peers. The results suggest neural correlates of the adolescent social reorientation toward peers and away from parents that may be associated with adolescents' real-life risk-taking behaviors and social relationships.

  13. Giant magnetostriction effect near onset of spin reorientation in MnBi

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Y.; Ryan, P. J.; McGuire, Michael A.

    In materials undergoing spontaneous symmetry breaking transitions, the emergence of multiple competing order parameters is pervasive. Employing in-field x-ray diffraction, we investigate the temperature and magnetic field dependence of the crystallographic structure of MnBi, elucidating the microscopic interplay between lattices and spin. The hexagonal phase of MnBi undergoes a spin reorientation transition (TSR), whereby the easy axis direction changes from the c axis to the basal plane. Across TSR, an abrupt symmetry change is accompanied by a clear sign change in the magnetostrictive coefficient, revealing that this transition corresponds to the onset of the spin reorientation. In the vicinity ofmore » TSR, a significantly larger in-plane magnetostrictive effect is observed, presenting the emergence of an intermediate phase that is highly susceptible to an applied magnetic field. X-ray linear dichroism shows that asymmetric Bi and Mn p orbitals do not play a role in the spin reorientation. Furthermore, this work suggests that the spin reorientation is caused by structural modification rather than changes in the local electronic configuration, providing a strategy for manipulating the magnetic anisotropy by external strain.« less

  14. Giant magnetostriction effect near onset of spin reorientation in MnBi

    DOE PAGES

    Choi, Y.; Ryan, P. J.; McGuire, Michael A.; ...

    2018-05-11

    In materials undergoing spontaneous symmetry breaking transitions, the emergence of multiple competing order parameters is pervasive. Employing in-field x-ray diffraction, we investigate the temperature and magnetic field dependence of the crystallographic structure of MnBi, elucidating the microscopic interplay between lattices and spin. The hexagonal phase of MnBi undergoes a spin reorientation transition (TSR), whereby the easy axis direction changes from the c axis to the basal plane. Across TSR, an abrupt symmetry change is accompanied by a clear sign change in the magnetostrictive coefficient, revealing that this transition corresponds to the onset of the spin reorientation. In the vicinity ofmore » TSR, a significantly larger in-plane magnetostrictive effect is observed, presenting the emergence of an intermediate phase that is highly susceptible to an applied magnetic field. X-ray linear dichroism shows that asymmetric Bi and Mn p orbitals do not play a role in the spin reorientation. Furthermore, this work suggests that the spin reorientation is caused by structural modification rather than changes in the local electronic configuration, providing a strategy for manipulating the magnetic anisotropy by external strain.« less

  15. Are we ready for sexual reorientation therapy in the U.S. military? A response to David W. Lutz.

    PubMed

    Hierholzer, Robert

    2004-01-01

    In his paper "The Catholic Church, the American Military, and Homosexual Reorientation Therapy," David W. Lutz ultimately concludes that it is "appropriate, and highly ethical" for the American military to offer reorientation therapy to help homosexuals overcome "the vice of sodomy." The major thrust of his paper, however, is to call for abandonment of the "Don't Ask/Don't Tell" policy currently in place in the military. Lutz's paper covers much ground, and this review begins by examining whether such a wide view is necessary for the ultimate conclusions. It goes on to ask whether Lutz has omitted to mention important considerations bearing on this issue, and whether Lutz's call for the introduction of reorientation therapy is a serious call or a symbolic response to homosexual activities. Lutz fails to address essential issues such as the actual experiences of other nations having homosexuals in the military, and issues regarding what constitutes "reorientation therapy," the latter leading to questions about how such a therapy would actually be implemented.

  16. Giant magnetostriction effect near onset of spin reorientation in MnBi

    NASA Astrophysics Data System (ADS)

    Choi, Y.; Ryan, P. J.; McGuire, M. A.; Sales, B. C.; Kim, J.-W.

    2018-05-01

    In materials undergoing spontaneous symmetry breaking transitions, the emergence of multiple competing order parameters is pervasive. Employing in-field x-ray diffraction, we investigate the temperature and magnetic field dependence of the crystallographic structure of MnBi, elucidating the microscopic interplay between lattices and spin. The hexagonal phase of MnBi undergoes a spin reorientation transition (TSR), whereby the easy axis direction changes from the c axis to the basal plane. Across TSR, an abrupt symmetry change is accompanied by a clear sign change in the magnetostrictive coefficient, revealing that this transition corresponds to the onset of the spin reorientation. In the vicinity of TSR, a significantly larger in-plane magnetostrictive effect is observed, presenting the emergence of an intermediate phase that is highly susceptible to an applied magnetic field. X-ray linear dichroism shows that asymmetric Bi and Mn p orbitals do not play a role in the spin reorientation. This work suggests that the spin reorientation is caused by structural modification rather than changes in the local electronic configuration, providing a strategy for manipulating the magnetic anisotropy by external strain.

  17. Reorientational Dynamics of Enzymes Adsorbed on Quartz: A Temperature-Dependent Time-Resolved TIRF Anisotropy Study

    PubMed Central

    Czeslik, C.; Royer, C.; Hazlett, T.; Mantulin, W.

    2003-01-01

    The preservation of enzyme activity and protein binding capacity upon protein adsorption at solid interfaces is important for biotechnological and medical applications. Because these properties are partly related to the protein flexibility and mobility, we have studied the internal dynamics and the whole-body reorientational rates of two enzymes, staphylococcal nuclease (SNase) and hen egg white lysozyme, over the temperature range of 20–80°C when the proteins are adsorbed at the silica/water interface and, for comparison, when they are dissolved in buffer. The data were obtained using a combination of two experimental techniques, total internal reflection fluorescence spectroscopy and time-resolved fluorescence anisotropy measurements in the frequency domain, with the protein Trp residues as intrinsic fluorescence probes. It has been found that the internal dynamics and the whole-body rotation of SNase and lysozyme are markedly reduced upon adsorption over large temperature ranges. At elevated temperatures, both protein molecules appear completely immobilized and the fractional amplitudes for the whole-body rotation, which are related to the order parameter for the local rotational freedom of the Trp residues, remain constant and do not approach zero. This behavior indicates that the angular range of the Trp reorientation within the adsorbed proteins is largely restricted even at high temperatures, in contrast to that of the dissolved proteins. The results of this study thus provide a deeper understanding of protein activity at solid surfaces. PMID:12668461

  18. Spin reorientation of a nonsymmetric body with energy dissipation

    NASA Technical Reports Server (NTRS)

    Cenker, R. J.

    1973-01-01

    Stable rotating semi-rigid bodies were demonstrated analytically, and verified in flights such as Explorer 1 and ATS-5 satellites. The problem arises from the two potential orientations which the final spin vector can take after large angle reorientation from minor to major axis, i.e., along the positive or negative axis of the maximum inertia. Reorientation of a satellite initially spinning about the minor axis using an energy dissipation device may require that the final spin orientation be controlled. Examples of possible applications are the Apogee Motor Assembly with Paired Satellites (AMAPS) configuration, where proper orientation of the thruster is required; and reorientation of ATS-5, where the spin sensitive nature of the despin device (yo-yo mechanism) requires that the final spin vector point is a specified direction.

  19. Computational prediction of propellant reorientation

    NASA Technical Reports Server (NTRS)

    Hochstein, John I.

    1987-01-01

    Viewgraphs from a presentation on computational prediction of propellant reorientation are given. Information is given on code verification, test conditions, predictions for a one-quarter scale cryogenic tank, pulsed settling, and preliminary results.

  20. Is Solute Rotation in an Ionic Liquid Influenced by the Addition of Glucose?

    PubMed

    Maurya, Rajan; Naithani, Sudhanshu; Bandyopadhyay, Dibyendu; Choudhury, Niharendu; Dutt, G B

    2017-12-07

    Fluorescence anisotropy measurements and molecular dynamics (MD) simulations have been performed to understand the specific interactions of two structurally similar nondipolar solutes, 2,5-dimethyl-1,4-dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole (DMDPP) and 1,4-dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole (DPP), with neat 1-butyl-3-methylimidazolium dicyanamide ([BMIM][N(CN) 2 ]) and also in the presence of glucose. It has been observed that the measured reorientation times of DMDPP in neat [BMIM][N(CN) 2 ] follow the predictions of the Stokes-Einstein-Debye hydrodynamic theory with slip boundary condition. Addition of glucose (0.075 and 0.15 mole fraction) has no bearing on the rotational diffusion of the solute apart from the viscosity related effects. In contrast, the reorientation times of DPP in neat [BMIM][N(CN) 2 ] obey stick boundary condition as the hydrogen bond donating solute experiences specific interactions with the dicyanamide anion. No influence of the additive can be noticed on the rotational diffusion of DPP at 0.075 mole fraction of glucose. However, at 0.15 mole fraction of glucose, the reorientation times of the solute at a given viscosity and temperature decrease by 15-40% compared to those obtained in the neat ionic liquid. MD simulations indicate that each DPP molecule hydrogen bonds with two dicyanamide anions in neat ionic liquid. The simulations also reveal that, at 0.15 mole fraction of glucose, the concentration of anions hydrogen bonded to glucose increases significantly; therefore, the percentage of solute molecules that can form hydrogen bonds with two dicyanamide anions decreases to 84, which leads to faster rotation of DPP.

  1. High Resolution NMR Studies of Encapsulated Proteins In Liquid Ethane

    PubMed Central

    Peterson, Ronald W.; Lefebvre, Brian G.; Wand, A. Joshua

    2005-01-01

    Many of the difficulties presented by large, aggregation-prone, and membrane proteins to modern solution NMR spectroscopy can be alleviated by actively seeking to increase the effective rate of molecular reorientation. An emerging approach involves encapsulating the protein of interest within the protective shell of a reverse micelle, and dissolving the resulting particle in a low viscosity fluid, such as the short chain alkanes. Here we present the encapsulation of proteins with high structural fidelity within reverse micelles dissolved in liquid ethane. The addition of appropriate co-surfactants can significantly reduce the pressure required for successful encapsulation. At these reduced pressures, the viscosity of the ethane solution is low enough to provide sufficiently rapid molecular reorientation to significantly lengthen the spin-spin NMR relaxation times of the encapsulated protein. PMID:16028922

  2. Photoinduced random molecular reorientation by nonradiative energy relaxation: An experimental test

    NASA Astrophysics Data System (ADS)

    Manzo, C.; Paparo, D.; Marrucci, L.

    2004-11-01

    By measuring the time-resolved fluorescence depolarization as a function of light excitation wavelength we address the question of a possible photoinduced orientational randomization of amino-anthraquinone dyes in liquid solutions. We find no significant dependence within the experimental uncertainties of both the initial molecule anisotropy and of the subsequent rotational diffusion dynamics on the photon energy. This indicates that this effect, if present, must be very small. A simple model of photoinduced local heating and corresponding enhanced rotational diffusion is in accordance with this result. This null result rules out some recent proposals that photoinduced local heating may contribute significantly to molecular reorientation effects in different materials. A small but statistically significant effect of photon energy is instead found in the excited-state lifetime of the dye.

  3. From environment to sustainable development: China's strategies for ESD in basic education

    NASA Astrophysics Data System (ADS)

    Zhang, Tiedao

    2010-06-01

    This paper intends to provide an overview of the reorientation of education in China in the period 1998-2009 with regard to development issues. During this time, the focus has shifted gradually from the environment and health to education for sustainable development. The article centres on highlighting the main interventions and strategies adopted by China's schools to make this reorientation possible, including: the introduction of new visions of sustainable development and project planning; the establishment of organisational mechanisms and capacity-building measures for their implementation in the field; the integration of ESD into teaching and learning processes; the maintenance of an action-research mechanism for innovations; and the sharing of lessons with both the national and the international community in order to make the implementation of ESD more effective.

  4. Could giant basin-forming impacts have killed Martian dynamo?

    PubMed Central

    Kuang, W; Jiang, W; Roberts, J; Frey, H V

    2014-01-01

    The observed strong remanent crustal magnetization at the surface of Mars suggests an active dynamo in the past and ceased to exist around early to middle Noachian era, estimated by examining remagnetization strengths in extant and buried impact basins. We investigate whether the Martian dynamo could have been killed by these large basin-forming impacts, via numerical simulation of subcritical dynamos with impact-induced thermal heterogeneity across the core-mantle boundary. We find that subcritical dynamos are prone to the impacts centered on locations within 30° of the equator but can easily survive those at higher latitudes. Our results further suggest that magnetic timing places a strong constraint on postimpact polar reorientation, e.g., a minimum 16° polar reorientation is needed if Utopia is the dynamo killer. PMID:26074641

  5. Could Giant Basin-Forming Impacts Have Killed Martian Dynamo?

    NASA Technical Reports Server (NTRS)

    Kuang, W.; Jiang, W.; Roberts, J.; Frey, H. V.

    2014-01-01

    The observed strong remanent crustal magnetization at the surface of Mars suggests an active dynamo in the past and ceased to exist around early to middle Noachian era, estimated by examining remagnetization strengths in extant and buried impact basins. We investigate whether the Martian dynamo could have been killed by these large basin-forming impacts, via numerical simulation of subcritical dynamos with impact-induced thermal heterogeneity across the core-mantle boundary. We find that subcritical dynamos are prone to the impacts centered on locations within 30 deg of the equator but can easily survive those at higher latitudes. Our results further suggest that magnetic timing places a strong constraint on postimpact polar reorientation, e.g., a minimum 16 deg polar reorientation is needed if Utopia is the dynamo killer.

  6. Could giant basin-forming impacts have killed Martian dynamo?

    PubMed

    Kuang, W; Jiang, W; Roberts, J; Frey, H V

    2014-11-28

    The observed strong remanent crustal magnetization at the surface of Mars suggests an active dynamo in the past and ceased to exist around early to middle Noachian era, estimated by examining remagnetization strengths in extant and buried impact basins. We investigate whether the Martian dynamo could have been killed by these large basin-forming impacts, via numerical simulation of subcritical dynamos with impact-induced thermal heterogeneity across the core-mantle boundary. We find that subcritical dynamos are prone to the impacts centered on locations within 30° of the equator but can easily survive those at higher latitudes. Our results further suggest that magnetic timing places a strong constraint on postimpact polar reorientation, e.g., a minimum 16° polar reorientation is needed if Utopia is the dynamo killer.

  7. Integration of orientation, clinorotation, and sensitivity in the graviresponse

    NASA Astrophysics Data System (ADS)

    Hasenstein, Karl H.; John, Susan

    Gravitropism describes the response of plants to some acceleration and typically involves amy-loplast displacement. Despite numerous studies, opinions diverge on the perception threshold and persistence of the stimulus. Short-term reorientation in the gravity field and superim-posed mechanostimulation (clinorotation) has the potential to reveal the duration (half-life) of mechanostimulation or memory persistence. Although clinorotation is commonly used to compensate the effect of continuous gravity stimulation, it adds long-term mechanostimulation to short-term reorientation. The constantly changing gravity vector is likely to interfere with curvature and root development. Especially sensitive are columella cells and entire layers have been shown to undergo programmed cell death upon clinorotation. It is unknown to what extent this response depends on the onset, speed, or duration of clinorotation. To determine the susceptibility of the graviresponse on clinorotation, we studied the effects of the rate (0.5 to 5 rpm) of rotation of reoriented flax roots (placed horizontally for 5, 10, or 15 min). Seedlings were kept in the dark, clinorotated either parallel or perpendicular to the root axis and imaged after each rotation by an infrared video camera. Horizontal clinorotation did not affect root growth rate (0.78±0.05 mm/h) but vertical clinorotation reduced root growth by more than 10%. The rate of clinorotation did not affect growth for either condition. However, maximal curvature for vertical clinorotation decreased with increasing rate of rotation and produced straight roots at 5 rpm. Horizontal clinorotation increased curvature with increasing reorienta-tion time and resulted in curvature that increased with the rotation rate. Thus, clinorotation changes the graviresponse but introduces secondary effects that depend on rate and direction of rotation.

  8. Factors influencing superimposition error of 3D cephalometric landmarks by plane orientation method using 4 reference points: 4 point superimposition error regression model.

    PubMed

    Hwang, Jae Joon; Kim, Kee-Deog; Park, Hyok; Park, Chang Seo; Jeong, Ho-Gul

    2014-01-01

    Superimposition has been used as a method to evaluate the changes of orthodontic or orthopedic treatment in the dental field. With the introduction of cone beam CT (CBCT), evaluating 3 dimensional changes after treatment became possible by superimposition. 4 point plane orientation is one of the simplest ways to achieve superimposition of 3 dimensional images. To find factors influencing superimposition error of cephalometric landmarks by 4 point plane orientation method and to evaluate the reproducibility of cephalometric landmarks for analyzing superimposition error, 20 patients were analyzed who had normal skeletal and occlusal relationship and took CBCT for diagnosis of temporomandibular disorder. The nasion, sella turcica, basion and midpoint between the left and the right most posterior point of the lesser wing of sphenoidal bone were used to define a three-dimensional (3D) anatomical reference co-ordinate system. Another 15 reference cephalometric points were also determined three times in the same image. Reorientation error of each landmark could be explained substantially (23%) by linear regression model, which consists of 3 factors describing position of each landmark towards reference axes and locating error. 4 point plane orientation system may produce an amount of reorientation error that may vary according to the perpendicular distance between the landmark and the x-axis; the reorientation error also increases as the locating error and shift of reference axes viewed from each landmark increases. Therefore, in order to reduce the reorientation error, accuracy of all landmarks including the reference points is important. Construction of the regression model using reference points of greater precision is required for the clinical application of this model.

  9. Shifting attention in viewer- and object-based reference frames after unilateral brain injury.

    PubMed

    List, Alexandra; Landau, Ayelet N; Brooks, Joseph L; Flevaris, Anastasia V; Fortenbaugh, Francesca C; Esterman, Michael; Van Vleet, Thomas M; Albrecht, Alice R; Alvarez, Bryan D; Robertson, Lynn C; Schendel, Krista

    2011-06-01

    The aims of the present study were to investigate the respective roles that object- and viewer-based reference frames play in reorienting visual attention, and to assess their influence after unilateral brain injury. To do so, we studied 16 right hemisphere injured (RHI) and 13 left hemisphere injured (LHI) patients. We used a cueing design that manipulates the location of cues and targets relative to a display comprised of two rectangles (i.e., objects). Unlike previous studies with patients, we presented all cues at midline rather than in the left or right visual fields. Thus, in the critical conditions in which targets were presented laterally, reorienting of attention was always from a midline cue. Performance was measured for lateralized target detection as a function of viewer-based (contra- and ipsilesional sides) and object-based (requiring reorienting within or between objects) reference frames. As expected, contralesional detection was slower than ipsilesional detection for the patients. More importantly, objects influenced target detection differently in the contralesional and ipsilesional fields. Contralesionally, reorienting to a target within the cued object took longer than reorienting to a target in the same location but in the uncued object. This finding is consistent with object-based neglect. Ipsilesionally, the means were in the opposite direction. Furthermore, no significant difference was found in object-based influences between the patient groups (RHI vs. LHI). These findings are discussed in the context of reference frames used in reorienting attention for target detection. Published by Elsevier Ltd.

  10. The reorientation of cell nucleus promotes the establishment of front-rear polarity in migrating fibroblasts.

    PubMed

    Maninová, Miloslava; Klímová, Zuzana; Parsons, J Thomas; Weber, Michael J; Iwanicki, Marcin P; Vomastek, Tomáš

    2013-06-12

    The establishment of cell polarity is an essential step in the process of cell migration. This process requires precise spatiotemporal coordination of signaling pathways that in most cells create the typical asymmetrical profile of a polarized cell with nucleus located at the cell rear and the microtubule organizing center (MTOC) positioned between the nucleus and the leading edge. During cell polarization, nucleus rearward positioning promotes correct microtubule organizing center localization and thus the establishment of front-rear polarity and directional migration. We found that cell polarization and directional migration require also the reorientation of the nucleus. Nuclear reorientation is manifested as temporally restricted nuclear rotation that aligns the nuclear axis with the axis of cell migration. We also found that nuclear reorientation requires physical connection between the nucleus and cytoskeleton mediated by the LINC (linker of nucleoskeleton and cytoskeleton) complex. Nuclear reorientation is controlled by coordinated activity of lysophosphatidic acid (LPA)-mediated activation of GTPase Rho and the activation of integrin, FAK (focal adhesion kinase), Src, and p190RhoGAP signaling pathway. Integrin signaling is spatially induced at the leading edge as FAK and p190RhoGAP are predominantly activated or localized at this location. We suggest that integrin activation within lamellipodia defines cell front, and subsequent FAK, Src, and p190RhoGAP signaling represents the polarity signal that induces reorientation of the nucleus and thus promotes the establishment of front-rear polarity. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Prison Industries: Turning Warehouses into Factories with Fences.

    ERIC Educational Resources Information Center

    Burger, Warren E.

    1985-01-01

    Chief Justice Burger urges elected representatives and public administrators to rethink corrections policy and to study the costs and benefits of prison industries. A long-time advocate of prison industries, Chief Justice Burger reviews recent public-private sector ventures to reorient corrections policy. (Author/CT)

  12. Reoriention of diprotonated DABCO (1,4-Diazabicyclo[2.2.2]octane) cation and proton transfer in organic ferroelectric adduct DABCO-2(2-Chlorobenzoic acid)

    NASA Astrophysics Data System (ADS)

    Asaji, Tetsuo

    2018-05-01

    Temperature dependences of 1H NMR as well as 35Cl NQR spin-lattice relaxation times T1 were investigated of a ferroelectric molecular adduct with Tc = 323 K, in which 1,4-diazabicyclo[2.2.2]octane (DABCO) is sandwiched between two 2-chlorobenzoic acid (2-ClBA). The NQR frequencies clearly show that proton transfer from 2-ClBA to DABCO is occurred and the molecular adduct consists of diprotonated DABCO cation and two 2-chlorobenzoate anions. The correlation time of reorientational motion of the diprotonated DABCO molecule was determined as a function of temperature. The activation energy Ea of the motion was estimated as 22 kJ mol-1 below Tc. The steep decrease of the NQR T1 with Ea = 50 kJ mol-1, observed above ca. 280 K in the ferroelectric phase, suggests a slow fluctuation of electric field gradient at chlorine nucleus.

  13. Organization of cortical microtubules in graviresponding maize roots

    NASA Technical Reports Server (NTRS)

    Blancaflor, E. B.; Hasenstein, K. H.

    1993-01-01

    Immunofluorescence labeling of cortical microtubules (MTs) was used to investigate the relationship between MT arrangement and changes in growth rate of the upper and lower sides of horizontally placed roots of maize (Zea mays L. cv. Merit). Cap cells and cells of the elongation zone of roots grown vertically in light or darkness showed MT arrangements that were transverse (perpendicular) to the growth direction. Microtubules of cells basal to the elongation zone typically showed oblique orientation. Two hours after horizontal reorientation, cap cells of gravicompetent, light-grown and curving roots contained MTs parallel to the gravity vector. The MT arrangement on the upper side of the elongation zone remained transverse but the MTs of the outer four to five layers of cortical cells along the lower side of the elongation zone showed reorientation parallel to the axis of the root. The MTs of the lower epidermis retained their transverse orientation. Dark-grown roots did not curve and did not show reorientation of MTs in cells of the root cap or elongation zone. The data indicate that MT depolymerization and reorientation is correlated with reduction in growth rate, and that MT reorientation is one of the steps of growth control of graviresponding roots.

  14. Free energy barrier for melittin reorientation from a membrane-bound state to a transmembrane state.

    PubMed

    Irudayam, Sheeba J; Pobandt, Tobias; Berkowitz, Max L

    2013-10-31

    An important step in a phospholipid membrane pore formation by melittin antimicrobial peptide is a reorientation of the peptide from a surface into a transmembrane conformation. Experiments measure the fraction of peptides in the surface state and the transmembrane state, but no computational study exists that quantifies the free energy curve for the reorientation. In this work we perform umbrella sampling simulations to calculate the potential of mean force (PMF) for the reorientation of melittin from a surface-bound state to a transmembrane state and provide a molecular level insight in understanding the peptide-lipid properties that influence the existence of the free energy barrier. The PMFs were calculated for a peptide to lipid (P/L) ratio of 1/128 and 4/128. We observe that the free energy barrier is reduced when the P/L ratio increases. In addition, we study the cooperative effect; specifically we investigate if the reorientation barrier is smaller for a second melittin, given that another neighboring melittin was already in the transmembrane orientation. We observe that indeed the barrier of the PMF curve is reduced in this case, thus confirming the presence of a cooperative effect.

  15. Molecular motions of [Beta]-carotene and a carotenoporphyrin dyad in solution. A carbon-13 NMR spin-lattice relaxation time study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, S.; Swindle, S.L.; Smith, S.K.

    1995-03-09

    Analysis of [sup 13]C NMR spin-lattice relaxation times (T[sub 1]) yields information concerning both overall tumbling of molecules in solution and internal rotations about single bonds. Relaxation time and nuclear Overhauser effect data have been obtained for [Beta]-carotene and two related molecules, squalane and squalene, for zinc meso-tetraphenylporphyrin, and for a dyad consisting of a porphyrin covalently linked to a carotenoid polyene through a trimethylene bridge. Squalane and squalene, which lack conjugated double bonds, behave essentially as limp string, with internal rotations at least as rapid as overall isotropic tumbling motions. In contrast, [Beta]-carotene reorients as a rigid rod, withmore » internal motions which are too slow to affect relaxation times. Modeling it as an anisotropic rotor yields a rotational diffusion coefficient for motion about the major axis which is 14 times larger than that for rotation about axes perpendicular to that axis. The porphyrin reorients more nearly isotropically and features internal librational motions about the single bonds to the phenyl groups. The relaxation time data for the carotenoporphyrin are consistent with internal motions similar to those of a medieval military flail. 31 refs., 3 figs., 5 tabs.« less

  16. Study of spin-ordering and spin-reorientation transitions in hexagonal manganites through Raman spectroscopy

    PubMed Central

    Chen, Xiang-Bai; Hien, Nguyen Thi Minh; Han, Kiok; Nam, Ji-Yeon; Huyen, Nguyen Thi; Shin, Seong-Il; Wang, Xueyun; Cheong, S. W.; Lee, D.; Noh, T. W.; Sung, N. H.; Cho, B. K.; Yang, In-Sang

    2015-01-01

    Spin-wave (magnon) scattering, when clearly observed by Raman spectroscopy, can be simple and powerful for studying magnetic phase transitions. In this paper, we present how to observe magnon scattering clearly by Raman spectroscopy, then apply the Raman method to study spin-ordering and spin-reorientation transitions of hexagonal manganite single crystal and thin films and compare directly with the results of magnetization measurements. Our results show that by choosing strong resonance condition and appropriate polarization configuration, magnon scattering can be clearly observed, and the temperature dependence of magnon scattering can be simple and powerful quantity for investigating spin-ordering as well as spin-reorientation transitions. Especially, the Raman method would be very helpful for investigating the weak spin-reorientation transitions by selectively probing the magnons in the Mn3+ sublattices, while leaving out the strong effects of paramagnetic moments of the rare earth ions. PMID:26300075

  17. Transport and dielectric properties of water and the influence of coarse-graining: Comparing BMW, SPC/E, and TIP3P models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braun, Daniel; Boresch, Stefan; Steinhauser, Othmar

    Long-term molecular dynamics simulations are used to compare the single particle dipole reorientation time, the diffusion constant, the viscosity, and the frequency-dependent dielectric constant of the coarse-grained big multipole water (BMW) model to two common atomistic three-point water models, SPC/E and TIP3P. In particular, the agreement between the calculated viscosity of BMW and the experimental viscosity of water is satisfactory. We also discuss contradictory values for the static dielectric properties reported in the literature. Employing molecular hydrodynamics, we show that the viscosity can be computed from single particle dynamics, circumventing the slow convergence of the standard approaches. Furthermore, our datamore » indicate that the Kivelson relation connecting single particle and collective reorientation time holds true for all systems investigated. Since simulations with coarse-grained force fields often employ extremely large time steps, we also investigate the influence of time step on dynamical properties. We observe a systematic acceleration of system dynamics when increasing the time step. Carefully monitoring energy/temperature conservation is found to be a sufficient criterion for the reliable calculation of dynamical properties. By contrast, recommended criteria based on the ratio of fluctuations of total vs. kinetic energy are not sensitive enough.« less

  18. Aqueous solvation from the water perspective.

    PubMed

    Ahmed, Saima; Pasti, Andrea; Fernández-Terán, Ricardo J; Ciardi, Gustavo; Shalit, Andrey; Hamm, Peter

    2018-06-21

    The response of water re-solvating a charge-transfer dye (deprotonated Coumarin 343) after photoexcitation has been measured by means of transient THz spectroscopy. Two steps of increasing THz absorption are observed, a first ∼10 ps step on the time scale of Debye relaxation of bulk water and a much slower step on a 3.9 ns time scale, the latter of which reflecting heating of the bulk solution upon electronic relaxation of the dye molecules from the S 1 back into the S 0 state. As an additional reference experiment, the hydroxyl vibration of water has been excited directly by a short IR pulse, establishing that the THz signal measures an elevated temperature within ∼1 ps. This result shows that the first step upon dye excitation (10 ps) is not limited by the response time of the THz signal; it rather reflects the reorientation of water molecules in the solvation layer. The apparent discrepancy between the relatively slow reorientation time and the general notion that water is among the fastest solvents with a solvation time in the sub-picosecond regime is discussed. Furthermore, non-equilibrium molecular dynamics simulations have been performed, revealing a close-to-quantitative agreement with experiment, which allows one to disentangle the contribution of heating to the overall THz response from that of water orientation.

  19. On the growth mechanisms of polar (100) surfaces of ceria on copper (100)

    NASA Astrophysics Data System (ADS)

    Hackl, Johanna; Duchoň, Tomáš; Gottlob, Daniel M.; Cramm, Stefan; Veltruská, Kateřina; Matolín, Vladimír; Nemšák, Slavomír; Schneider, Claus M.

    2018-05-01

    We present a study of temperature dependent growth of nano-sized ceria islands on a Cu (100) substrate. Low-energy electron microscopy, micro-electron diffraction, X-ray absorption spectroscopy, and photoemission electron microscopy are used to determine the morphology, shape, chemical state, and crystal structure of the grown islands. Utilizing real-time observation capabilities, we reveal a three-way interaction between the ceria, substrate, and local oxygen chemical potential. The interaction manifests in the reorientation of terrace boundaries on the Cu (100) substrate, characteristic of the transition between oxidized and metallic surface. The reorientation is initiated at nucleation sites of ceria islands, whose growth direction is influenced by the proximity of the terrace boundaries. The grown ceria islands were identified as fully stoichiometric CeO2 (100) surfaces with a (2 × 2) reconstruction.

  20. Effect of CorrelatedRotational Noise

    NASA Astrophysics Data System (ADS)

    Hancock, Benjamin; Wagner, Caleb; Baskaran, Aparna

    The traditional model of a self-propelled particle (SPP) is one where the body axis along which the particle travels reorients itself through rotational diffusion. If the reorientation process was driven by colored noise, instead of the standard Gaussian white noise, the resulting statistical mechanics cannot be accessed through conventional methods. In this talk we present results comparing three methods of deriving the statistical mechanics of a SPP with a reorientation process driven by colored noise. We illustrate the differences/similarities in the resulting statistical mechanics by their ability to accurately capture the particles response to external aligning fields.

  1. Neural correlates of adolescents’ viewing of parents’ and peers’ emotions: Associations with risk-taking behavior and risky peer affiliations

    PubMed Central

    Saxbe, Darby; Del Piero, Larissa; Immordino-Yang, Mary Helen; Kaplan, Jonas; Margolin, Gayla

    2015-01-01

    Social reorientation from parents to same-age peers is normative in adolescence, but the neural correlates of youths’ socioemotional processing of parents and peers have not been explored. In the current study, twenty-two adolescents (average age 16.98) underwent neuroimaging (fMRI) while viewing and rating emotions shown in brief video clips featuring themselves, their parents, or an unfamiliar peer. Viewing self vs. other and parents vs. the peer activated regions in the medial prefrontal cortex (mPFC), replicating prior findings that this area responds to self-relevant stimuli, including familiar and not just similar others (Kreinen, Tu, & Buckner, 2010). Viewing the peer compared with parents elicited activation in posterior ‘mentalizing’ structures, the precuneus, posterior cingulate cortex (PCC), bilateral pSTS and right TPJ, as well as the ventral striatum and bilateral amygdala and hippocampus. Relative activations in the PCC and precuneus to the peer vs. the parent were related both to reported risk-taking behavior and to affiliations with more risk-taking peers. The results suggest neural correlates of the adolescent social reorientation towards peers and away from parents that may be associated with adolescents’ real-life risk-taking behaviors and social relationships. PMID:25874749

  2. Fluorescence quenching studies of potential-dependent DNA reorientation dynamics at glassy carbon electrode surfaces.

    PubMed

    Li, Qin; Cui, Chenchen; Higgins, Daniel A; Li, Jun

    2012-09-05

    The potential-dependent reorientation dynamics of double-stranded DNA (ds-DNA) attached to planar glassy carbon electrode (GCE) surfaces were investigated. The orientation state of surface-bound ds-DNA was followed by monitoring the fluorescence from a 6-carboxyfluorescein (FAM6) fluorophore covalently linked to the distal end of the DNA. Positive potentials (i.e., +0.2 V vs open circuit potential, OCP) caused the ds-DNA to align parallel to the electrode surface, resulting in strong dipole-electrode quenching of FAM6 fluorescence. Switching of the GCE potential to negative values (i.e., -0.2 V vs OCP) caused the ds-DNA to reorient perpendicular to the electrode surface, with a concomitant increase in FAM6 fluorescence. In addition to the very fast (submilliseconds) dynamics of the initial reorientation process, slow (0.1-0.9 s) relaxation of FAM6 fluorescence to intermediate levels was also observed after potential switching. These dynamics have not been previously described in the literature. They are too slow to be explained by double layer charging, and chronoamperometry data showed no evidence of such effects. Both the amplitude and rate of the dynamics were found to depend upon buffer concentration, and ds-DNA length, demonstrating a dependence on the double layer field. The dynamics are concluded to arise from previously undetected complexities in the mechanism of potential-dependent ds-DNA reorientation. The possible origins of these dynamics are discussed. A better understanding of these dynamics will lead to improved models for potential-dependent ds-DNA reorientation at electrode surfaces and will facilitate the development of advanced electrochemical devices for detection of target DNAs.

  3. Use of geometric properties of landmark arrays for reorientation relative to remote cities and local objects.

    PubMed

    Mou, Weimin; Nankoo, Jean-François; Zhou, Ruojing; Spetch, Marcia L

    2014-03-01

    Five experiments investigated how human adults use landmark arrays in the immediate environment to reorient relative to the local environment and relative to remote cities. Participants learned targets' directions with the presence of a proximal 4 poles forming a rectangular shape and an array of more distal poles forming a rectangular shape. Then participants were disoriented and pointed to targets with the presence of the proximal poles or the distal poles. Participants' orientation was estimated by the mean of their pointing error across targets. The targets could be 7 objects in the immediate local environment in which the poles were located or 7 cities around Edmonton (Alberta, Canada) where the experiments occurred. The directions of the 7 cities could be learned from reading a map first and then from pointing to the cities when the poles were presented. The directions of the 7 cities could also be learned from viewing labels of cities moving back and forth in the specific direction in the immediate local environment in which the poles were located. The shape of the array of the distal poles varied in salience by changing the number of poles on each edge of the rectangle (2 vs. 34). The results showed that participants regained their orientation relative to local objects using the distal poles with 2 poles on each edge; participants could not reorient relative to cities using the distal pole array with 2 poles on each edge but could reorient relative to cities using the distal pole array with 34 poles on each edge. These results indicate that use of cues in reorientation depends not only on the cue salience but also on which environment people need to reorient to.

  4. Young children's use of features to reorient is more than just associative: further evidence against a modular view of spatial processing.

    PubMed

    Newcombe, Nora S; Ratliff, Kristin R; Shallcross, Wendy L; Twyman, Alexandra D

    2010-01-01

    Proponents of a geometric module have argued that instances of young children's use of features as well as geometry to reorient can be explained by a two-stage process. In this model, only the first stage is a true reorientation, accomplished by using geometric information alone; features are considered in a second stage using association (Lee, Shusterman & Spelke, 2006). This account is contradicted by the data from two experiments. Experiment 1a sets the stage for Experiment 1b by showing that young children use geometric information to reorient in a complex geometric figure without a single principal axis of symmetry (an octagon). In such a figure, there are two sets of geometrically congruent corners, with four corners in each set. The addition of a colored wall leads to the existence of three geometrically congruent but, crucially, all unmarked corners; using the colored wall to distinguish among them could not be done associatively. In Experiment 1b, both 3- and 5-year-old children showed true non-associative reorientation using features by performing at above-chance levels on all-white trials. Experiment 2 used a paradigm without distinctive geometry, modeled on Lee et al. (2006), involving an equilateral triangle of hiding places located within a circular enclosure, but with a large stable feature rather than a small moveable one. Four-year-olds (the age group studied by Lee et al.) used features at above-chance levels. Thus, features can be used to reorient, in a way not dependent on association, in contradiction to the two-stage version of the modular view.

  5. Physical strain-mediated microtubule reorientation in the epidermis of gravitropically or phototropically stimulated maize coleoptiles.

    PubMed

    Fischer, K; Schopfer, P

    1998-07-01

    During gravitropic and phototropic curvature of the maize coleoptile, the cortical microtubules (MTs) adjacent to the outer epidermal cell wall assume opposite orientations at the two sides of the organ. Starting from a uniformly random pattern during straight growth in darkness, the MTs reorientate perpendicularly to the organ axis at the outer (faster growing) side and parallel to the organ axis at the inner (slower growing) side. As similar reorientations can be induced during straight growth by increasing or decreasing the effective auxin concentration, it has been proposed that these reorientations may be used as a diagnostic test for assessing the auxin status of the epidermal cells during tropic curvature. This idea was tested by determining the MT orientations in the coleoptile of intact maize seedlings in which the gravitropic or phototropic curvature was prevented or inversed by an appropriate mechanical counterforce. Forces that just prevented the coleoptile from curving in a gravity or light field prevented reorientations of the MTs. Forces strong enough to overcompensate the tropic stimuli by enforcing curvature in the opposite direction induced reorientations of the MTs opposite to those produced by tropic stimulation. These results show that the MTs at the outer surface of the coleoptile respond to changes in mechanical tissue strain rather than to gravitropic or phototropic stimuli and associated changes at the level of auxin or any other element in the signal transduction chain between perception of tropic stimuli and asymmetric growth response. It is proposed that cortical MTs can act as strain gauges in a positive feed-back regulatory circle utilized for amplification and stabilization of environmentally induced changes in the direction of elongation growth.

  6. Is language necessary for human spatial reorientation? Reconsidering evidence from dual task paradigms.

    PubMed

    Ratliff, Kristin R; Newcombe, Nora S

    2008-03-01

    Being able to reorient to the spatial environment after disorientation is a basic adaptive challenge. There is clear evidence that reorientation uses geometric information about the shape of the surrounding space. However, there has been controversy concerning whether use of geometry is a modular function, and whether use of features is dependent on human language. A key argument for the role of language comes from shadowing findings where adults engaged in a linguistic task during reorientation ignored a colored wall feature and only used geometric information to reorient [Hermer-Vazquez, L., Spelke, E., & Katsnelson, A. (1999). Sources of flexibility in human cognition: Dual task studies of space and language. Cognitive Psychology, 39, 3-36]. We report three studies showing: (a) that the results of Hermer-Vazques et al. [Hermer-Vazquez, L., Spelke, E., & Katsnelson, A. (1999). Sources of flexibility in human cognition: Dual task studies of space and language. Cognitive Psychology, 39, 3-36] are obtained in incidental learning but not with explicit instructions, (b) that a spatial task impedes use of features at least as much as a verbal shadowing task, and (c) that neither secondary task impedes use of features in a room larger than that used by Hermer-Vazquez et al. These results suggest that language is not necessary for successful use of features in reorientation. In fact, whether or not there is an encapsulated geometric module is currently unsettled. The current findings support an alternative to modularity; the adaptive combination view hypothesizes that geometric and featural information are utilized in varying degrees, dependent upon the certainty and variance with which the two kinds of information are encoded, along with their salience and perceived usefulness.

  7. Time-lapse analysis of gravitropism in Ceratodon protonemata

    NASA Technical Reports Server (NTRS)

    Young, J. C.; Sack, F. D.

    1992-01-01

    The tip cell of the protonema of the moss Ceratodon purpureus (Hedw.) Brid. is negatively gravitropic when grown in the dark on supplemented agar. Gravitropism, plastid distribution, and plastid movement were studied in living cells using time-lapse video microscopy and infrared light. A wrong-way (downward) curvature preceded upward curvature and was detected as early as 2 minutes after reorientation. Upward curvature began 30-45 minutes after reorientation to the horizontal. Cell division temporarily reversed upward curvature, but did not inhibit wrong-way curvature. Since significant amyloplast sedimentation always occurred before the start of upward curvature, it is possible that these amyloplasts function as statoliths for upward curvature. However, no significant amyloplast sedimentation occurred before wrong-way curvature. Thus, this early phase of gravitropism cannot require plastid sedimentation for gravity sensing. Most plastids moved within and between zones, and plastid zonation was highly dynamic. Plastids moved toward the apex and toward the base of the cell at rates much slower than cytoplasmic streaming. Despite the dynamic nature of plastid movement and zonation, during upward curvature the distance between sedimented plastids and the apex stayed constant. Time-lapse analysis has revealed intriguing events not readily seen previously using destructive sampling.

  8. Run-and-tumble-like motion of active colloids in viscoelastic media

    NASA Astrophysics Data System (ADS)

    Lozano, Celia; Ruben Gomez-Solano, Juan; Bechinger, Clemens

    2018-01-01

    Run-and-tumble motion is a prominent locomotion strategy employed by many living microorganisms. It is characterized by straight swimming intervals (runs), which are interrupted by sudden reorientation events (tumbles). In contrast, directional changes of synthetic microswimmers (active particles) are caused by rotational diffusion, which is superimposed with their translational motion and thus leads to rather continuous and slow particle reorientations. Here we demonstrate that active particles can also perform a swimming motion where translational and orientational changes are disentangled, similar to run-and-tumble. In our system, such motion is realized by a viscoelastic solvent and a periodic modulation of the self-propulsion velocity. Experimentally, this is achieved using light-activated Janus colloids, which are illuminated by a time-dependent laser field. We observe a strong enhancement of the effective translational and rotational motion when the modulation time is comparable to the relaxation time of the viscoelastic fluid. Our findings are explained by the relaxation of the elastic stress, which builds up during the self-propulsion, and is suddenly released when the activity is turned off. In addition to a better understanding of active motion in viscoelastic surroundings, our results may suggest novel steering strategies for synthetic microswimmers in complex environments.

  9. Fluidization, resolidification, and reorientation of the endothelial cell in response to slow tidal stretches

    PubMed Central

    Krishnan, Ramaswamy; Canović, Elizabeth Peruski; Iordan, Andreea L.; Rajendran, Kavitha; Manomohan, Greeshma; Pirentis, Athanassios P.; Smith, Michael L.; Butler, James P.; Fredberg, Jeffrey J.

    2012-01-01

    Mechanical stretch plays an important role in regulating shape and orientation of the vascular endothelial cell. This morphological response to stretch is basic to angiogenesis, neovascularization, and vascular homeostasis, but mechanism remains unclear. To elucidate mechanisms, we used cell mapping rheometry to measure traction forces in primary human umbilical vein endothelial cells subjected to periodic uniaxial stretches. Onset of periodic stretch of 10% strain amplitude caused a fluidization response typified by attenuation of traction forces almost to zero. As periodic stretch continued, the prompt fluidization response was followed by a slow resolidification response typified by recovery of the traction forces, but now aligned along the axis perpendicular to the imposed stretch. Reorientation of the cell body lagged reorientation of the traction forces, however. Together, these observations demonstrate that cellular reorientation in response to periodic stretch is preceded by traction attenuation by means of cytoskeletal fluidization and subsequent traction recovery transverse to the stretch direction by means of cytoskeletal resolidification. PMID:22700796

  10. Optimal reorientation of asymmetric underactuated spacecraft using differential flatness and receding horizon control

    NASA Astrophysics Data System (ADS)

    Cai, Wei-wei; Yang, Le-ping; Zhu, Yan-wei

    2015-01-01

    This paper presents a novel method integrating nominal trajectory optimization and tracking for the reorientation control of an underactuated spacecraft with only two available control torque inputs. By employing a pseudo input along the uncontrolled axis, the flatness property of a general underactuated spacecraft is extended explicitly, by which the reorientation trajectory optimization problem is formulated into the flat output space with all the differential constraints eliminated. Ultimately, the flat output optimization problem is transformed into a nonlinear programming problem via the Chebyshev pseudospectral method, which is improved by the conformal map and barycentric rational interpolation techniques to overcome the side effects of the differential matrix's ill-conditions on numerical accuracy. Treating the trajectory tracking control as a state regulation problem, we develop a robust closed-loop tracking control law using the receding-horizon control method, and compute the feedback control at each control cycle rapidly via the differential transformation method. Numerical simulation results show that the proposed control scheme is feasible and effective for the reorientation maneuver.

  11. Microgravity liquid propellant management

    NASA Technical Reports Server (NTRS)

    Hung, R. J.

    1990-01-01

    The requirement to settle or to position liquid fluid over the outlet end of a spacecraft propellant tank prior to main engine restart, poses a microgravity fluid behavior problem. Resettlement or reorientation of liquid propellant can be accomplished by providing optimal acceleration to the spacecraft such that the propellant is reoriented over the tank outlet without any vapor entrainment, any excessive geysering, or any other undersirable fluid motion for the space fluid management under microgravity environment. The most efficient technique is studied for propellant resettling through the minimization of propellant usage and weight penalties. Both full scale and subscale liquid propellant tank of Space Transfer Vehicle were used to simulate flow profiles for liquid hydrogen reorientation over the tank outlet. In subscale simulation, both constant and impulsive resettling acceleration were used to simulate the liquid flow reorientation. Comparisons between the constant reverse gravity acceleration and impulsive reverse gravity acceleration to be used for activation of propellant resettlement shows that impulsive reverse gravity thrust is superior to constant reverse gravity thrust.

  12. The Response of the Left Ventral Attentional System to Invalid Targets and its Implication for the Spatial Neglect Syndrome: a Multivariate fMRI Investigation.

    PubMed

    Silvetti, Massimo; Lasaponara, Stefano; Lecce, Francesca; Dragone, Alessio; Macaluso, Emiliano; Doricchi, Fabrizio

    2016-12-01

    In humans, invalid visual targets that mismatch spatial expectations induced by attentional cues are considered to selectively engage a right hemispheric "reorienting" network that includes the temporal parietal junction (TPJ), the inferior frontal gyrus (IFG), and the medial frontal gyrus (MFG). However, recent findings suggest that this hemispheric dominance is not absolute and that it is rather observed because the TPJ and IFG areas in the left hemisphere are engaged both by invalid and valid cued targets. Because of this, the BOLD response of the left hemisphere to invalid targets is usually cancelled out by the standard "invalid versus valid" contrast used in functional magnetic resonance imaging investigations of spatial attention. Here, we used multivariate pattern recognition analysis (MVPA) to gain finer insight into the role played by the left TPJ and IFG in reorienting to invalid targets. We found that in left TPJ and IFG blood oxygen level-dependent (BOLD) responses to invalid and valid targets were associated to different patterns of neural activity, possibly reflecting the presence of functionally distinct neuronal populations. Pattern segregation was significant at group level, it was present in almost all of the participants to the study and was observed both for targets in the left and right side of space. A control whole-brain MVPA ("Searchlight" analysis) confirmed the results obtained in predefined regions of interest and highlighted that also other areas, that is, superior parietal and frontal-polar cortex, show different patterns of BOLD response to valid and invalid targets. These results confirm and expand previous evidence highlighting the involvement of the left hemisphere in reorienting of visual attention (Doricchi et al. 2010; Dragone et al. 2015). These findings suggest that asymmetrical reorienting deficits suffered by right brain damaged patients with left spatial neglect, who have severe impairments in contralesional reorienting and less severe impairments in ipsilesional reorienting, are due to preserved reorienting abilities in the intact left hemisphere. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Reorienting the GWOT to Win the Moral Level of War

    DTIC Science & Technology

    2006-05-25

    50 Giovanna Borradori, Philosophy In A Time of Terror: Dialogues with Juergen Habermas and Jacques Derrida (Chicago: The University of...60 BIBLIOGRAPHY Borradori, Giovanna. Philosophy In A Time of Terror: Dialogues with Juergen Habermas and Jacques Derrida . Chicago: The University of...will, last for decades. 17 Deregulating the State’s Monopoly on War In the 18th Century, Jean- Jacques Rousseau presented his theory of the Social

  14. Accessible GPS: Reorientation and Target Location among Users with Visual Impairments

    ERIC Educational Resources Information Center

    Ponchillia, Paul E.; Rak, Eniko C.; Freeland, Amy L.; LaGrow, Steven J.

    2007-01-01

    This article presents the results of two single-subject experiments that were designed to determine consumers' ability to use a BrailleNote GPS. The participants decreased their mean orientation time from 6 minutes to 45 seconds and increased their target-location efficiency fourfold with BGPS than without BGPS. Additional results and implications…

  15. Every Other Day. Keynote Address.

    ERIC Educational Resources Information Center

    Tiller, Tom

    Schools need to be reoriented and restructured so that what is taught and learned, and the way in which it is taught and learned, are better integrated with young people's real-world experiences. Many indicators suggest that the meaningful aspects of school have been lost in the encounter with modern times. The title of this address--"Every…

  16. Colleges Urged to Instill "Charitable Impulse" in Students, Inspire Them to Reorient Public Policy as Well as Donate Their Time and Money.

    ERIC Educational Resources Information Center

    McMillen, Liz

    1987-01-01

    The president of the Council on Foundations, James A. Joseph, urges educators to develop volunteers who can eliminate the causes of social problems. Colleges and universities are in a special position to instill a sense of social responsibility in students. (MLW)

  17. Proliferation of Small Arms and Light Weapons in West Africa: Implications for Subregional Security

    DTIC Science & Technology

    2007-06-15

    recruits for violent or rebel organizations. He employs the analogy of Sierra Leone where despite disarmament, the unemployed youths 21 still...infrastructure and the people’s corrupted psychic will take along time to be reoriented. More so, the future of the nation will continue to be

  18. Reimagining Environmental Education within Academia: Storytelling and Dialogue as Lived Ecofeminist Politics

    ERIC Educational Resources Information Center

    Piersol, Laura; Timmerman, Nora

    2017-01-01

    During this time of ecological crises, ecofeminist theory and practice is vital for challenging ecological and social injustice. We begin this article by briefly unpacking the critique of essentialism that has had a silencing and divisive effect on the field of ecofeminism. Through this exploration we reorient away from essentializing or…

  19. Epitaxial Ni-Mn-Ga films deposited on SrTiO{sub 3} and evidence of magnetically induced reorientation of martensitic variants at room temperature

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heczko, O.; Thomas, M.; Buschbeck, J.

    2008-02-18

    Epitaxial Ni-Mn-Ga films were grown on SrTiO{sub 3} by sputter deposition. The films deposited at 673 K are ferromagnetic and martensitic at room temperature. Pole figure measurements indicate that the twinned orthorhombic martensite microstructure of the film has a lower symmetry compared to bulk. Magnetically induced reorientation or magnetic shape memory effect is indicated by magnetization curve measurements. Though the overall extension of the film is constrained by a rigid substrate, the reorientation is possible due to the additional degree of freedom in the orthorhombic phase.

  20. NMR (Nuclear Magnetic Resonance) of solid biopolymers

    NASA Technical Reports Server (NTRS)

    Andrew, E. R.

    1983-01-01

    It has been possible through the study of proton relaxation in solid proteins and related molecules to identify and characterize the following molecular motions which contribute to relaxation: (1) methyl group reorientation; (2) segmental motion; (3) side chain motion; (4) proline ring puckering; and (5) water molecule reorientation.

  1. Educating Academic Staff to Reorient Curricula in ESD

    ERIC Educational Resources Information Center

    Biasutti, Michele; Makrakis, Vassilios; Concina, Eleonora; Frate, Sara

    2018-01-01

    Purpose: The purpose of this paper is to present a professional development experience for higher education academic staff within the framework of an international Tempus project focused on reorienting university curricula to address sustainability. The project included revising curricula to phase sustainable development principles into university…

  2. Differential white matter involvement associated with distinct visuospatial deficits after right hemisphere stroke.

    PubMed

    Carter, Alex R; McAvoy, Mark P; Siegel, Joshua S; Hong, Xin; Astafiev, Serguei V; Rengachary, Jennifer; Zinn, Kristi; Metcalf, Nicholas V; Shulman, Gordon L; Corbetta, Maurizio

    2017-03-01

    Visuospatial attention depends on the integration of multiple processes, and people with right hemisphere lesions after a stroke may exhibit severe or no visuospatial deficits. The anatomy of core components of visuospatial attention is an area of intense interest. Here we examine the relationship between the disruption of core components of attention and lesion distribution in a heterogeneous group (N = 70) of patients with right hemisphere strokes regardless of the presence of clinical neglect. Deficits of lateralized spatial orienting, measured as the difference in reaction times for responding to visual targets in the contralesional or ipsilesional visual field, and deficits in re-orienting attention, as measured by the difference in reaction times for invalidly versus validly cued targets, were measured using a computerized spatial orienting task. Both measures were related through logistic regression and a novel ridge regression method to anatomical damage measured with magnetic resonance imaging. While many regions were common to both deficit maps, a deficit in lateralized spatial orienting was more associated with lesions in the white matter underlying the posterior parietal cortex, and middle and inferior frontal gyri. A deficit in re-orienting of attention toward unattended locations was associated with lesions in the white matter of the posterior parietal cortex, insular cortex and less so with white matter involvement of the anterior frontal lobe. An hodological analysis also supports this partial dissociation between the white matter tracts that are damaged in lateralized spatial biases versus impaired re-orienting. Our results underscore that the integrity of fronto-parietal white matter tracts is crucial for visuospatial attention and that different attention components are mediated by partially distinct neuronal substrates. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Analysis of the rivets from the RMS Titanic using experimental and theoretical techniques

    NASA Astrophysics Data System (ADS)

    Hooper, Jennifer Jo

    Earlier studies of Titanic wrought iron rivets revealed an anisotropic, inhomogeneous composite material composed of glassy iron silicate (slag) particles embedded in a ferrite matrix. Micrographs indicated a directional character to the slag "stringers" that follows the method of processing---aligned parallel to the shaft in the center of the rivet, but oriented perpendicular to the shaft within the inner section of each head. It was proposed that the re-orientation of large slag particles in the rivet head weakened this region, predisposing the rivets to fail as a result of collision with the iceberg. Using quantitative metallography, mechanical testing, and a combination of modeling techniques, this hypothesis was tested using 35 Titanic rivets and additional contemporary wrought iron. Results revealed that the wrought iron microstructure showed a high slag content that was very coarse and unevenly distributed. Results from micro structural, chemical and mechanical analysis, as well as supporting historical evidence, suggested that two types of rivets, both wrought iron and steel, were used on the Titanic. Tensile testing results indicated that the longitudinal orientation in wrought iron possesses an average of 20% higher tensile strength and nearly four times the ductility of the transverse orientation. Results for Titanic rivet steel suggest a 100MPa enhancement in yield strength and tensile strength over wrought iron. Sequential imaging during mechanical testing, supported by micromechanical modeling predictions, indicated that the mechanical behavior of wrought iron is strongly affected by the orientation, distribution and content of slag within the matrix. Finite element analysis of a wrought iron rivet with anisotropic properties demonstrated that, because of poor ductility produced by the re-orientation of slag within the head, a Titanic rivet could not withstand a 5mm displacement of the hull's steel plates. Due to its low ultimate tensile strength, the wrought iron rivet would fail after an additional load that is 2.5 times less than that required for the steel rivet failure. This evidence suggests that as a result of the collision with the iceberg, failure at the junction of the head and shaft caused "popping" of rivet's heads and the opening of riveted seams.

  4. Gravitropism of cut shoots is mediated by oxidative processes: A physiological and molecular study

    NASA Astrophysics Data System (ADS)

    Philosoph-Hadas, Sonia; Friedman, Haya; Meir, Shimon

    2012-07-01

    The signal transduction events occurring during shoot gravitropism are mediated through amyloplasts sedimentation, reorientation of actin filaments in the endodermis, and differential changes in level and action of auxin, associated with differential growth leading to shoot curvature. Since increase in reactive oxygen species (ROS) was shown to be associated with growth, we examined the possible use of antioxidants in controlling the gravitropic response, via their interaction with events preceding shoot bending. Reoriented snapdragon (Antirrhinum majus L.) spikes and tomato (Solanum lycopersicum cv. MicroTom) shoots showed a visual upward bending after a lag period of 3 or 5 h, respectively, which was inhibited by the antioxidants N-acetyl-cysteine (NAC) and reduced glutathione (GSH). This suggests the involvement of oxidative reactions in the process. The two antioxidants prevented the sedimentation of amyloplasts to the bottom of the endodermis cells following 0.5-5 h of snapdragon shoot reorientation, suggesting that oxidative reactions are involved already at a very early signal perception stage prior to the visual bending. In addition, a differential distribution in favor of the lower shoot side of various oxidative elements, including H2O2 concentrations and activity of the NADPH-oxidase enzyme, was observed during reorientation of snapdragon spikes. Application of the two antioxidants reduced the levels of these elements and abolished their differential distribution across the shoot. On the other hand, the activity of the antioxidative enzyme, superoxide dismutase (SOD), which was not differentially distributed across the shoot, increased significantly following application of the two antioxidants. The auxin redistribution in reoriented shoots was analyzed using transgenic tomato plants expressing the GUS reporter gene under the Aux/IAA4 promoter (a generous gift of M. Bouzayen, France). GUS response, detected in control shoots 4 h after their reorientation in favor of the lower shoot side was completely eliminated in the NAC-treated shoots, in which the bending response was inhibited. These results suggest that the gravitropic-induced asymmetric auxin redistribution precedes shoot bending, and NAC inhibits this response by abolishing the auxin gradient across the shoot. Our microarray analysis of tomato shoots, using the Affymetrix Tomato GeneChip, revealed differential changes in expression of 266 genes, occurring during the initial 0.5-5 h of shoot reorientation prior to bending. The differential changes in expression of auxin-related genes in favor of the lower shoot side occurred already following 0.5 h of reorientation, while those of cell wall-related genes, associated with shoot bending, occurred only 3 h following shoot reorientation. Among the identified genes, 11 genes were related to auxin, and 36 genes were associated with oxidative processes, demonstrating the involvement of ROS in early events of shoot gravitropism. Taken together, our results suggest that ROS mediate the early gravity-induced amyloplast sedimentation required for signal perception, as well as the lateral auxin movement across the shoot, which is necessary for the auxin asymmetric distribution leading to shoot upward bending.

  5. (Not) Keeping the stem straight: a proteomic analysis of maritime pine seedlings undergoing phototropism and gravitropism.

    PubMed

    Herrera, Raul; Krier, Catherine; Lalanne, Celine; Ba, El Hadji Maodo; Stokes, Alexia; Salin, Franck; Fourcaud, Thierry; Claverol, Stéphane; Plomion, Christophe

    2010-10-06

    Plants are subjected to continuous stimuli from the environment and have evolved an ability to respond through various growth and development processes. Phototropism and gravitropism responses enable the plant to reorient with regard to light and gravity. We quantified the speed of maritime pine seedlings to reorient with regard to light and gravity over 22 days. Seedlings were inclined at 15, 30 and 45 degrees with vertical plants as controls. A lateral light source illuminated the plants and stem movement over time was recorded. Depending on the initial angle of stem lean, the apical response to the lateral light source differed. In control and 15° inclined plants, the apex turned directly towards the light source after only 2 h. In plants inclined at 30° and 45°, the apex first reoriented in the vertical plane after 2 h, then turned towards the light source after 24 h. Two-dimensional gel electrophoresis coupled with mass spectrometry was then used to describe the molecular response of stem bending involved in photo- and gravi-tropism after 22 hr and 8 days of treatment. A total of 486 spots were quantitatively analyzed using image analysis software. Significant changes were determined in the protein accumulation of 68 protein spots. Early response gravitropic associated proteins were identified, which are known to function in energy related and primary metabolism. A group of thirty eight proteins were found to be involved in primary metabolism and energy related metabolic pathways. Degradation of Rubisco was implicated in some protein shifts. Our study demonstrates a rapid gravitropic response in apices of maritime pine seedlings inclined >30°. Little or no response was observed at the stem bases of the same plants. The primary gravitropic response is concomitant with a modification of the proteome, consisting of an over accumulation of energy and metabolism associated proteins, which may allow the stem to reorient rapidly after bending.

  6. (Not) Keeping the stem straight: a proteomic analysis of maritime pine seedlings undergoing phototropism and gravitropism

    PubMed Central

    2010-01-01

    Background Plants are subjected to continuous stimuli from the environment and have evolved an ability to respond through various growth and development processes. Phototropism and gravitropism responses enable the plant to reorient with regard to light and gravity. Results We quantified the speed of maritime pine seedlings to reorient with regard to light and gravity over 22 days. Seedlings were inclined at 15, 30 and 45 degrees with vertical plants as controls. A lateral light source illuminated the plants and stem movement over time was recorded. Depending on the initial angle of stem lean, the apical response to the lateral light source differed. In control and 15° inclined plants, the apex turned directly towards the light source after only 2 h. In plants inclined at 30° and 45°, the apex first reoriented in the vertical plane after 2 h, then turned towards the light source after 24 h. Two-dimensional gel electrophoresis coupled with mass spectrometry was then used to describe the molecular response of stem bending involved in photo- and gravi-tropism after 22 hr and 8 days of treatment. A total of 486 spots were quantitatively analyzed using image analysis software. Significant changes were determined in the protein accumulation of 68 protein spots. Early response gravitropic associated proteins were identified, which are known to function in energy related and primary metabolism. A group of thirty eight proteins were found to be involved in primary metabolism and energy related metabolic pathways. Degradation of Rubisco was implicated in some protein shifts. Conclusions Our study demonstrates a rapid gravitropic response in apices of maritime pine seedlings inclined >30°. Little or no response was observed at the stem bases of the same plants. The primary gravitropic response is concomitant with a modification of the proteome, consisting of an over accumulation of energy and metabolism associated proteins, which may allow the stem to reorient rapidly after bending. PMID:20925929

  7. Power-induced evolution and increased dimensionality of nonlinear modes in reorientational soft matter.

    PubMed

    Laudyn, Urszula A; Jung, Paweł S; Zegadło, Krzysztof B; Karpierz, Miroslaw A; Assanto, Gaetano

    2014-11-15

    We demonstrate the evolution of higher order one-dimensional guided modes into two-dimensional solitary waves in a reorientational medium. The observations, carried out at two different wavelengths in chiral nematic liquid crystals, are in good agreement with a simple nonlocal nonlinear model.

  8. Viscosity, relaxation time, and dynamics within a model asphalt of larger molecules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Derek D.; Greenfield, Michael L., E-mail: greenfield@egr.uri.edu

    2014-01-21

    The dynamics properties of a new “next generation” model asphalt system that represents SHRP AAA-1 asphalt using larger molecules than past models is studied using molecular simulation. The system contains 72 molecules distributed over 12 molecule types that range from nonpolar branched alkanes to polar resins and asphaltenes. Molecular weights range from 290 to 890 g/mol. All-atom molecular dynamics simulations conducted at six temperatures from 298.15 to 533.15 K provide a wealth of correlation data. The modified Kohlrausch-Williams-Watts equation was regressed to reorientation time correlation functions and extrapolated to calculate average rotational relaxation times for individual molecules. The rotational relaxationmore » rate of molecules decreased significantly with increasing size and decreasing temperature. Translational self-diffusion coefficients followed an Arrhenius dependence. Similar activation energies of ∼42 kJ/mol were found for all 12 molecules in the model system, while diffusion prefactors spanned an order of magnitude. Viscosities calculated directly at 533.15 K and estimated at lower temperatures using the Debye-Stokes-Einstein relationship were consistent with experimental data for asphalts. The product of diffusion coefficient and rotational relaxation time showed only small changes with temperature above 358.15 K, indicating rotation and translation that couple self-consistently with viscosity. At lower temperatures, rotation slowed more than diffusion.« less

  9. Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution.

    PubMed

    Hu, Chen; Fang, Jianwen; Borchardt, Ronald T; Schowen, Richard L; Kuczera, Krzysztof

    2008-04-01

    S-Adenosyl-L-homocysteine hydrolase (SAHH) is an enzyme regulating intracellular methylation reactions. The homotetrameric SAHH exists in an open conformation in absence of substrate, while enzyme:inhibitor complexes crystallize in the closed conformation, in which the ligands are engulfed by the protein due to an 18 degrees domain reorientation within each of the four subunits. We present a microscopic description of the structure and dynamics of the substrate-free, NAD(+)-bound SAHH in solution, based on a 15-ns molecular dynamics simulation in explicit solvent. In the trajectory, the four cofactor-binding domains formed a relatively rigid core with structure very similar to the crystal conformation. The four substrate-binding domains, located at the protein exterior, also retained internal structures similar to the crystal, while undergoing large amplitude rigid-body reorientations. The trajectory domain motions exhibited two interesting properties. First, within each subunit the domains fluctuated between open and closed conformations, while at the tetramer level 80% of the domain motions were perpendicular to the direction of the open-to-closed structural transition. Second, the domain reorientations in solution could be represented as a sum of two components, faster, with 20-50 ps correlation time and 3-4 degrees amplitude, and slower, with 8-23 ns correlation time and amplitude of 14-22 degrees . The faster motion is similar to the 1.5 cm(-1) frequency hinge-bending vibrations found in our recent normal mode analysis (Wang et al., Biochemistry 2005;44:7228-7239). The slower motion agrees with fluorescence anisotropy decay measurements, which detected a 10-20 ns domain reorientation of ca. 26 degrees amplitude in the substrate-free enzyme (Wang et al., Biochemistry 2006;45:7778-7786). Our simulations are thus in excellent agreement with experimental data. The simulations allow us to assign the observed nanosecond fluorescence anisotropy signal to fluctuations in domain orientations, and indicate that the microscopic mechanism of the motion involves rotational diffusion within a cone of 10-20 degrees . Overall, our simulation results complement the existing experimental data and provide important new insights into SAHH domain motions in solution, which play a crucial role in the catalytic mechanism of SAHH. (c) 2007 Wiley-Liss, Inc.

  10. A comprehensive study of layer-specific morphological changes in the microstructure of carotid arteries under uniaxial load.

    PubMed

    Krasny, Witold; Morin, Claire; Magoariec, Hélène; Avril, Stéphane

    2017-07-15

    The load bearing properties of large blood vessels are principally conferred by collagen and elastin networks and their microstructural organization plays an important role in the outcomes of various arterial pathologies. In particular, these fibrous networks are able to rearrange and reorient spatially during mechanical deformations. In this study, we investigate for the first time whether these well-known morphological rearrangements are the same across the whole thickness of blood vessels, and subsequently if the underlying mechanisms that govern these rearrangements can be predicted using affine kinematics. To this aim, we submitted rabbit carotid samples to uniaxial load in three distinct deformation directions, while recording live images of the 3D microstructure using multiphoton microscopy. Our results show that the observed realignment of collagen and elastin in the media layer, along with elastin of the adventitia layer, remained limited to small angles that can be predicted by affine kinematics. We show also that collagen bundles of fibers in the adventitia layer behaved in significantly different fashion. They showed a remarkable capacity to realign in the direction of the load, whatever the loading direction. Measured reorientation angles of the fibers were significantly higher than affine predictions. This remarkable property of collagen bundles in the adventitia was never observed before, it shows that the medium surrounding collagen in the adventitia undergoes complex deformations challenging traditional hyperelastic models based on mixture theories. The biomechanical properties of arteries are conferred by the rearrangement under load of the collagen and elastin fibers making up the arterial microstructure. Their kinematics under deformation is not yet characterized for all fiber networks. In this respect we have submitted samples of arterial tissue to uniaxial tension, simultaneously to confocal imaging of their microstructure. Our method allowed identifying for the first time the remarkable ability of adventitial collagen fibers to reorient in the direction of the load, achieving reorientation rotations that exceeded those predicted by affine kinematics, while all other networks followed the affine kinematics. Our results highlight new properties of the microstructure, which might play a role in the outcomes of vascular pathologies like aneurysms. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  11. Social and Non-Social Cueing of Visuospatial Attention in Autism and Typical Development

    ERIC Educational Resources Information Center

    Pruett, John R.; LaMacchia, Angela; Hoertel, Sarah; Squire, Emma; McVey, Kelly; Todd, Richard D.; Constantino, John N.; Petersen, Steven E.

    2011-01-01

    Three experiments explored attention to eye gaze, which is incompletely understood in typical development and is hypothesized to be disrupted in autism. Experiment 1 (n = 26 typical adults) involved covert orienting to box, arrow, and gaze cues at two probabilities and cue-target times to test whether reorienting for gaze is endogenous, exogenous,…

  12. Effects of ultra-vacuum and space environment on contact ohmic resistance: LDEF experiment AO 138-11

    NASA Technical Reports Server (NTRS)

    Assie, Jean-Pierre; Perotto, Alfred

    1992-01-01

    The FRECOPA experimentation of chemical resistance of electrical connector contacts, as described, has evidenced the detrimental time variations of nickel plated conductors and gilded copper contacts, irrespective of crimping storage or metal peening conditions. With a view to reorient aluminum technology a silvered aluminum conductor/gilded aluminum contact solution was evaluated.

  13. From Environment to Sustainable Development: China's Strategies for ESD in Basic Education

    ERIC Educational Resources Information Center

    Zhang, Tiedao

    2010-01-01

    This paper intends to provide an overview of the reorientation of education in China in the period 1998-2009 with regard to development issues. During this time, the focus has shifted gradually from the environment and health to education for sustainable development. The article centres on highlighting the main interventions and strategies adopted…

  14. Why Size Counts: Children's Spatial Reorientation in Large and Small Enclosures

    ERIC Educational Resources Information Center

    Learmonth, Amy E.; Newcombe, Nora S.; Sheridan, Natalie; Jones, Meredith

    2008-01-01

    When mobile organisms are spatially disoriented, for instance by rapid repetitive movement, they must re-establish orientation. Past research has shown that the geometry of enclosing spaces is consistently used for reorientation by a wide variety of species, but that non-geometric features are not always used. Based on these findings, some…

  15. Reorientation in a Rhombic Environment: No Evidence for an Encapsulated Geometric Module

    ERIC Educational Resources Information Center

    Hupbach, A.; Nadel, L.

    2005-01-01

    Reorientation behavior of young children has been described as dependent upon a geometric module that is incapable of interacting with landmark information. Whereas previous studies typically used rectangular spaces that provided geometric information about distance, we used a rhombic space that allowed us to explore the way children use geometric…

  16. Blade motion and nutrient flux to the kelp, Eisenia arborea.

    PubMed

    Denny, Mark; Roberson, Loretta

    2002-08-01

    Marine algae rely on currents and waves to replenish the nutrients required for photosynthesis. The interaction of algal blades with flow often involves dynamic reorientations of the blade surface (pitching and flapping) that may in turn affect nutrient flux. As a first step toward understanding the consequences of blade motion, we explore the effect of oscillatory pitching on the flux to a flat plate and to two morphologies of the kelp Eisenia arborea. In slow flow (equivalent to a water velocity of 2.7 cm s(-1)), pitching increases the time-averaged flux to both kelp morphologies, but not to the plate. In fast flow (equivalent to 20 cm s(-1) in water), pitching has negligible effect on flux regardless of shape. For many aspects of flux, the flat plate is a reliable model for the flow-protected algal blade, but predictions made from the plate would substantially underestimate the flux to the flow-exposed blade. These measurements highlight the complexities of flow-related nutrient transport and the need to understand better the dynamic interactions among nutrient flux, blade motion, blade morphology, and water flow.

  17. Scientific and technical training in the Soviet Union

    NASA Technical Reports Server (NTRS)

    Spearman, M. L.

    1983-01-01

    Specific features and observations on the Soviet educational system and areas of apparent effectiveness are presented, noting that the literacy rate is over 98 percent in 1982. Educational goals are reoriented every five years to match with other projections of five-year plans. The Soviet constitution established strong educational goals, including schools, correspondence courses, lectures in native tongues, free tuition, and vocational training. The educational pattern from pre-school through graduate school lasts over 28 yr and contains two 2-yr periods of work, confined to specialties after graduate school. Mathematics is emphasized, as are physics, Marxism, and a foreign language. Approximately 300,000 engineers were graduated in the Soviet Union in 1982, compared with the 20-yr U.S. average of 50,000/yr. About 2/3 of Soviet engineers participate in defense work, a number which is four times the total number of U.S. engineers. It is asserted that the continual indoctrination, organization, and practical work experience will guarantee that the Soviet state will remain a dominant force in the world as long as centralized state control can be carried out.

  18. Do hydrodynamic interactions affect the swim pressure?

    PubMed

    Burkholder, Eric W; Brady, John F

    2018-05-09

    We study the motion of a spherical active Brownian particle (ABP) of size a, moving with a fixed speed U0, and reorienting on a time scale τR in the presence of a confining boundary. Because momentum is conserved in the embedding fluid, we show that the average force per unit area on the boundary equals the bulk mechanical pressure P∞ = p∞f + Π∞, where p∞f is the fluid pressure and Π∞ is the particle pressure; this is true for active and passive particles alike regardless of how the particles interact with the boundary. As an example, we investigate how hydrodynamic interactions (HI) change the particle-phase pressure at the wall, and find that Πwall = n∞(kBT + ζ(Δ)U0l(Δ)/6), where ζ is the (Stokes) drag on the swimmer, l = U0τR is the run length, and Δ is the minimum gap size between the particle and the wall; as Δ → ∞ this is the familiar swim pressure [Takatori et al., Phys. Rev. Lett., 2014, 113, 1-5].

  19. A morphometric analysis of the redistribution of organelles in columella cells of horizontally-oriented roots of Zea mays

    NASA Technical Reports Server (NTRS)

    Moore, R.

    1986-01-01

    In order to determine what structural changes in graviperceptive cells are associated with onset of root gravicurvature, the redistribution of organelles in columella cells of horizontally-oriented, graviresponding roots of Zea mays has been quantified. Root gravicurvature began by 15 min after reorientation, and did not involve significant changes in the (i) volume of individual columella cells or amyloplasts, (ii) relative volume of any cellular organelle, (iii) number of amyloplasts per columella cell, or (iv) surface area of cellular location of endoplasmic reticulum. Sedimentation of amyloplasts began within 1 to 2 min after reorientation, and was characterized by an intensely staining area of cytoplasm adjacent to the sedimenting amyloplasts. By 5 min after reorientation, amyloplasts were located in the lower distal corner of columella cells, and, by 15 min after reorientation, overlaid the entire length of the lower cell wall. No consistent contact between amyloplasts and any cellular structure was detected at any stage of gravicurvature. Centrally-located nuclei initially migrated upward in columella cells of horizontally-oriented roots, after which they moved to the proximal ends of the cells by 15 min after reorientation. No significant pattern of redistribution of vacuoles, mitochondria, dictyosomes, or hyaloplasm was detected that correlated with the onset of gravicurvature. These results indicate that amyloplasts and nuclei are the only organelles whose movements correlate positively with the onset of gravicurvature by primary roots of this cultivar of Zea mays.

  20. Angles No Longer Weigh In: The Effect of Geometric Cue Directness on Reorientation

    ERIC Educational Resources Information Center

    Huang, Zhenzhen; Hu, Qingfen; Shao, Yi

    2017-01-01

    Previous research in spatial reorientation, which only presented the target location in the corner, has found that adults weighed angles more than wall lengths. We proposed that in previous research, angular cues were available for direct use whereas length cues had to be associated with the left/right sense. We thus investigated whether the…

  1. The World Is Not Flat: Can People Reorient Using Slope?

    ERIC Educational Resources Information Center

    Nardi, Daniele; Newcombe, Nora S.; Shipley, Thomas F.

    2011-01-01

    Studies of spatial representation generally focus on flat environments and visual input. However, the world is not flat, and slopes are part of most natural environments. In a series of 4 experiments, we examined whether humans can use a slope as a source of allocentric, directional information for reorientation. A target was hidden in a corner of…

  2. Education for Sustainability in University Studies: A Model for Reorienting the Curriculum

    ERIC Educational Resources Information Center

    Junyent, Merce; de Ciurana, Anna M. Geli

    2008-01-01

    A decisive factor for achieving a culture of sustainability is university training for future professionals. The aim of this article is to bring new elements to the process of reorienting university studies towards sustainability. Presented here is the ACES model (Curriculum Greening of Higher Education, acronym in Spanish), which is the result of…

  3. Medium-frequency impulsive-thrust-activated liquid hydrogen reorientation with Geyser

    NASA Technical Reports Server (NTRS)

    Hung, R. J.; Shyu, K. L.

    1992-01-01

    Efficient technique are studied for accomplishing propellant resettling through the minimization of propellant usage through impulsive thrust. A comparison between the use of constant-thrust and impulsive-thrust accelerations for the activation of propellant resettlement shows that impulsive thrust is superior to constant thrust for liquid reorientation in a reduced-gravity environment. This study shows that when impulsive thrust with 0.1-1.0-, and 10-Hz frequencies for liquid-fill levels in the range between 30-80 percent is considered, the selection of 1.0-Hz-frequency impulsive thrust over the other frequency ranges of impulsive thrust is the optimum. Characteristics of the slosh waves excited during the course of 1.0-Hz-frequency impulsive-thrust liquid reorientation were also analyzed.

  4. Peak broadening and peak shift pole figures investigations by STRESS-SPEC diffractometer at FRM II

    NASA Astrophysics Data System (ADS)

    Gan, W. M.; Randau, C.; Hofmann, M.; Brokmeier, H. G.; Mueller, M.; Schreyer, A.

    2012-02-01

    This paper studied for the first time peak intensity, peak position and FHWM pole figures with one time measurement at the neutron diffractometer STRESS-SPEC via in-situ tensile deformation on austenitic steel. Fibre distribution with its evolution from central tensile direction to normal direction of these three kinds of pole figures was obtained. Variation of peak position and FWHM can be correlated to the reorientation of the texture component.

  5. A New Type of ECT Stimuli: Burst Stimulus ECT.

    PubMed

    Aksay, S S; Bumb, J M; Janke, C; Kranaster, L; Sartorius, A

    2015-11-01

    Pulse width in electroconvulsive therapy has significant influence on effectiveness and side effects. While shorter pulses are beneficial for cognitive performance, there is still a debate about a negative impact on ECT efficacy at least for ultra-brief pulse durations. We report a first patient treated with burst stimulus ECT, i. e., with 4 consecutive 250-µs pulses, separated by another 250 µs. Within the same patient we compared 6 classical vs. 6 burst stimulus ECT sessions. In all cases a typical tonic-clonic seizure was observed. Seizure parameters like concordance, coherence and mid-ictal amplitude increased numerically, but not significantly with burst ECT. The time needed to show a reorientation was significantly shortened with burst stimuli (30 min vs. 14 min, p=0.007). In conclusion we present the first case of ECT in a single patient comparing "classical" single stimulus pulses vs. burst stimulus ECT. The new burst stimulus was better tolerated regarding reorientation time after the treatment, while parameters of seizure quality remained basically unchanged. Whether burst stimulus ECT has the potential to improve ECT quality by reducing side effects without losing efficacy has to be investigated in clinical trials. © Georg Thieme Verlag KG Stuttgart · New York.

  6. The Influence of Cue Reliability and Cue Representation on Spatial Reorientation in Young Children

    ERIC Educational Resources Information Center

    Lyons, Ian M.; Huttenlocher, Janellen; Ratliff, Kristin R.

    2014-01-01

    Previous studies of children's reorientation have focused on cue representation (e.g., whether cues are geometric) as a predictor of performance but have not addressed cue reliability (the regularity of the relation between a given cue and an outcome) as a predictor of performance. Here we address both factors within the same series of…

  7. Use of Geometric Properties of Landmark Arrays for Reorientation Relative to Remote Cities and Local Objects

    ERIC Educational Resources Information Center

    Mou, Weimin; Nankoo, Jean-François; Zhou, Ruojing; Spetch, Marcia L.

    2014-01-01

    Five experiments investigated how human adults use landmark arrays in the immediate environment to reorient relative to the local environment and relative to remote cities. Participants learned targets' directions with the presence of a proximal 4 poles forming a rectangular shape and an array of more distal poles forming a rectangular shape. Then…

  8. Children Reorient Using the Left/Right Sense of Coloured Landmarks at 18-24 Months

    ERIC Educational Resources Information Center

    Nardini, Marko; Atkinson, Janette; Burgess, Neil

    2008-01-01

    In previous studies, children disoriented in small enclosures used room shape, but not wall colors, to find hidden objects. Their reorientation was said to depend solely on a "geometric module" informationally encapsulated with respect to color. We argue that previous studies did not fully evaluate children's use of color owing to a bias in the…

  9. The overlap between false belief and spatial reorientation in the temporo-parietal junction: The role of input modality and task.

    PubMed

    Özdem, Ceylan; Brass, Marcel; Van der Cruyssen, Laurens; Van Overwalle, Frank

    2017-04-01

    Neuroimaging research has demonstrated that the temporo-parietal junction (TPJ) is activated when unexpected stimuli appear in spatial reorientation tasks as well as during thinking about the beliefs of other people triggered by verbal scenarios. While the role of potential common component processes subserved by the TPJ has been extensively studied to explain this common activation, the potential confounding role of input modality (spatial vs. verbal) has been largely ignored. To investigate the role of input modality apart from task processes, we developed a novel spatial false belief task based on moving shapes. We explored the overlap in TPJ activation across this novel task and traditional tasks of spatial reorientation (Posner) and verbal belief (False Belief vs. Photo stories). The results show substantial overlap across the same spatial input modality (both reorientation and false belief) as well as across the common task process (verbal and spatial belief), but no triple overlap. This suggests the potential for an overarching function of the TPJ, with some degree of specialization in different subregions due to modality, function and connectivity. The results are discussed with respect to recent theoretical models of the TPJ.

  10. Diapir-induced reorientation of Saturn's moon Enceladus.

    PubMed

    Nimmo, Francis; Pappalardo, Robert T

    2006-06-01

    Enceladus is a small icy satellite of Saturn. Its south polar region consists of young, tectonically deformed terrain and has an anomalously high heat flux. This heat flux is probably due to localized tidal dissipation within either the ice shell or the underlying silicate core. The surface deformation is plausibly due to upwelling of low-density material (diapirism) as a result of this tidal heating. Here we show that the current polar location of the hotspot can be explained by reorientation of the satellite's rotation axis because of the presence of a low-density diapir. If the diapir is in the ice shell, then the shell must be relatively thick and maintain significant rigidity (elastic thickness greater than approximately 0.5 km); if the diapir is in the silicate core, then Enceladus cannot possess a global subsurface ocean, because the core must be coupled to the overlying ice for reorientation to occur. The reorientation generates large (approximately 10 MPa) tectonic stress patterns that are compatible with the observed deformation of the south polar region. We predict that the distribution of impact craters on the surface will not show the usual leading hemisphere-trailing hemisphere asymmetry. A low-density diapir also yields a potentially observable negative gravity anomaly.

  11. Re-evaluating the role of TPJ in attentional control: Contextual updating?☆

    PubMed Central

    Geng, Joy J.; Vossel, Simone

    2013-01-01

    The right temporo-parietal junction (TPJ) is widely considered as part of a network that reorients attention to task-relevant, but currently unattended stimuli (Corbetta and Shulman, 2002). Despite the prevalence of this theory in cognitive neuroscience, there is little direct evidence for the principal hypothesis that TPJ sends an early reorientation signal that “circuit breaks” attentional processing in regions of the dorsal attentional network (e.g., the frontal eye fields) or is completely right lateralized during attentional processing. In this review, we examine both functional neuroimaging work on TPJ in the attentional literature as well as anatomical findings. We first critically evaluate the idea that TPJ reorients attention and is right lateralized; we then suggest that TPJ signals might rather reflect post-perceptual processes involved in contextual updating and adjustments of top-down expectations; and then finally discuss how these ideas relate to the electrophysiological (P300) literature, and to TPJ findings in other cognitive and social domains. We conclude that while much work is needed to define the computational functions of regions encapsulated as TPJ, there is now substantial evidence that it is not specialized for stimulus-driven attentional reorienting. PMID:23999082

  12. Magnetism of Ho 1-xTb xAl₂ alloys: Critical dependence of a first-order transition on Tb concentration

    DOE PAGES

    Khan, Mahmud; Mudryk, Ya.; Gschneidner, K. A.; ...

    2011-12-27

    HoAl₂ exhibits a first-order spin reorientation transition at 20 K, which is manifested as a sharp peak in the heat capacity. When Ho is partially replaced by only 5% of Tb, the sharp heat-capacity peak in Ho 1-xTb xAl₂ (x = 0.05) disappears, and then reappears again for x ≥ 0.07. For x = 0.05, the anomaly corresponding to the spin reorientation transition is barely seen in the heat capacity, but as x exceeds 0.07 the weak anomaly transforms to a sharp peak. The spin reorientation transition temperature increases to 29 K for x = 0.05, and as x increasesmore » further the transition shifts to lower temperature and returns to ~20 K for x = 0.25. The transition is no longer observed when x exceeds 0.60. Temperature-dependent x-ray powder-diffraction data confirm the first-order nature of the spin reorientation transition for the alloy with x = 0.40, and indicate that the compound retains the room-temperature cubic structure within the sensitivity of the technique. Experimental observations are discussed considering the easy magnetization directions of HoAl₂ and TbAl₂.« less

  13. FIELD DEPENDENCE OF THE SPIN REORIENTATION TEMPERATURE IN MICRO AND NANOCRYSTALLINE FORMS OF Nd{sub 2}Fe{sub 14}B.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LEWIS,L.H.; HARLAND,C.L.

    2002-08-18

    Insight into the anisotropy behavior of Nd{sub 2}Fe{sub 14}B may be obtained by measurements of the spin reorientation temperature T{sub S} where the overall magnetocrystalline anisotropy changes to allow the magnetic moment to relax from an easy axis to an easy cone configuration. DC magnetization measurements made at various applied fields on sintered and nanocrystalline forms of Nd{sub 2}Fe{sub 14}B indicate a T{sub S} that remains constant for the sintered sample but is strongly field-dependent for the nanocrystalline forms of the material. Specifically, T{sub S} decreases with decreasing applied fields of strengths 5 T, 1 T and 0.01 T. Amore » simple model that minimizes the total energy of the system leads to the conclusion that the spin reorientation temperature is insensitive to applied field. Therefore it is concluded that the apparent decrease in the system's spin reorientation temperatures with decrease in measuring field can be attributed to the nanoscale structure of the system and a difference in the anisotropy constants compared to their bulk values.« less

  14. Electron paramagnetic resonance studies of slowly tumbling vanadyl spin probes in nematic liquid crystals

    NASA Technical Reports Server (NTRS)

    Bruno, G. V.; Harrington, J. K.; Eastman, M. P.

    1978-01-01

    An analysis of EPR line shapes by the method of Polnaszek, Bruno, and Freed is made for slowly tumbling vanadyl spin probes in viscous nematic liquid crystals. The use of typical vanadyl complexes as spin probes for nematic liquid crystals is shown to simplify the theoretical analysis and the subsequent interpretation. Rotational correlation times tau and orientational ordering parameters S sub Z where slow tumbling effects are expected to be observed in vanadyl EPR spectra are indicated in a plot. Analysis of the inertial effects on the probe reorientation, which are induced by slowly fluctuating torque components of the local solvent structure, yield quantitative values for tau and S sub Z. The weakly ordered probe VOAA is in the slow tumbling region and displays these inertial effects throughout the nematic range of BEPC and Phase V. VOAA exhibits different reorientation behavior near the isotropic-nematic transition temperature than that displayed far below this transition temperature.

  15. Versatile low-Reynolds-number swimmer with three-dimensional maneuverability.

    PubMed

    Jalali, Mir Abbas; Alam, Mohammad-Reza; Mousavi, SeyyedHossein

    2014-11-01

    We design and simulate the motion of a swimmer, the Quadroar, with three-dimensional translation and reorientation capabilities in low-Reynolds-number conditions. The Quadroar is composed of an I-shaped frame whose body link is a simple linear actuator and four disks that can rotate about the axes of flange links. The time symmetry is broken by a combination of disk rotations and the one-dimensional expansion or contraction of the body link. The Quadroar propels on forward and transverse straight lines and performs full three-dimensional reorientation maneuvers, which enable it to swim along arbitrary trajectories. We find continuous operation modes that propel the swimmer on planar and three-dimensional periodic and quasiperiodic orbits. Precessing quasiperiodic orbits consist of slow lingering phases with cardioid or multiloop turns followed by directional propulsive phases. Quasiperiodic orbits allow the swimmer to access large parts of its neighboring space without using complex control strategies. We also discuss the feasibility of fabricating a nanoscale Quadroar by photoactive molecular rotors.

  16. Curvature induced L-defects in water conduction in carbon nanotubes.

    PubMed

    Zimmerli, Urs; Gonnet, Pedro G; Walther, Jens H; Koumoutsakos, Petros

    2005-06-01

    We conduct molecular dynamics simulations to study the effect of the curvature induced static dipole moment of small open-ended single-walled carbon nanotubes (CNTs) immersed in water. This dipole moment generates a nonuniform electric field, changing the energy landscape in the CNT and altering the water conduction process. The CNT remains practically filled with water at all times, whereas intermittent filling is observed when the dipole term is not included. In addition, the dipole moment induces a preferential orientation of the water molecules near the end regions of the nanotube, which in turn causes a reorientation of the water chain in the middle of the nanotube. The most prominent feature of this reorientation is an L-defect in the chain of water molecules inside the CNT. The analysis of the water energetics and structural characteristics inside and in the vicinity of the CNT helps to identify the role of the dipole moment and to suggest possible mechanisms for controlled water and proton transport at the nanoscale.

  17. Control of spin ambiguity during reorientation of an energy dissipating body

    NASA Technical Reports Server (NTRS)

    Kaplan, M. H.; Cenker, R. J.

    1973-01-01

    A quasi-rigid body initially spinning about its minor principal axis and experiencing energy dissipation will enter a tumbling mode and eventually reorient itself such that stable spin about its major principal axis is achieved. However, in this final state the body may be spinning in a positive or negative sense with respect to its major axis and aligned in a positive or negative sense with the inertially fixed angular momentum vector. This ambiguity can be controlled only through an active system. The associated dynamical formulations and simulations of uncontrolled reorientations are presented. Three control schemes are discussed and results offered for specific examples. These schemes include displacement of internal masses, spinning up of internal inertia, and reaction jets, all of which have demonstrated the ability to control spin ambiguity.

  18. Spin reorientation transition and near room-temperature multiferroic properties in a W-type hexaferrite SrZn{sub 1.15}Co{sub 0.85}Fe{sub 16}O{sub 27}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Song, Y. Q.; Fang, Y.; Wang, L. Y.

    2014-03-07

    In this Letter, we investigate the magnetic and multiferroic properties of a W-type hexaferrite SrZn{sub 1.15}Co{sub 0.85}Fe{sub 16}O{sub 27}. Due to the strong planar contribution to the anisotropy provided by Co{sup 2+} ions, this hexaferrite shows a spin reorientation transition from easy-axis to easy-cone at 302 K, which is different from the onset temperature of ferroelectric polarization, 275 K. By applying magnetic field, a remarkable drop of polarization is observed, suggesting a large magnetoelectric effect in this multiferroics. The difference between spin reorientation and ferroelectric phase transition temperature as well as the origin of magnetoelectric effect are discussed.

  19. Spin reorientations in Tb-Fe films grown on polyimide substrates

    NASA Astrophysics Data System (ADS)

    Maneesh, K. Sai; Arout Chelvane, J.; Talapatra, A.; Basumatary, Himalay; Mohanty, J.; Kamat, S. V.

    2018-02-01

    This paper reports the effect of film thickness and rapid thermal annealing on the spin reorientations in Tb-Fe films grown on flexible polyimide substrates. Magnetization studies indicated that the spins reorient from in-plane to out-of-plane direction with increase in film thicknesses. This was confirmed by magnetic force microscopy studies which showed weak featureless contrast for films deposited with lower thickness and a strong out-of-plane contrast for films grown with higher thicknesses. On subsequent rapid thermal annealing all the Tb-Fe films exhibited in-plane magnetic anisotropy. The results were explained based on competition between uniaxial and shape anisotropies, nature of residual stresses as well as nucleation of crystalline Fe phase in an amorphous Tb-Fe matrix on rapid thermal annealing.

  20. GIPAW (gauge including projected augmented wave) and local dynamics in 13C and 29Si solid state NMR: the study case of silsesquioxanes (RSiO1.5)8.

    PubMed

    Gervais, Christel; Bonhomme-Coury, Laure; Mauri, Francesco; Babonneau, Florence; Bonhomme, Christian

    2009-08-28

    Octameric silsesquioxanes (RSiO(1.5))(8) are versatile and interesting nano building blocks, suitable for the synthesis of nanocomposites with controlled porosity. In this paper, we revisit the (29)Si and (13)C solid state NMR spectroscopy for this class of materials, by using GIPAW (gauge including projected augmented wave) first principles calculations [Pickard & Mauri, Phys. Rev. B, 2001, 63, 245101]. Full tensorial data, including the chemical shift anisotropies (CSA) and the absolute orientation of the corresponding principal axes systems (PAS), were calculated. Subsequent averaging of the calculated tensors (due to fast reorientation of the R groups around the Si-C bonds) allowed for the interpretation of the strong reduction of CSA and dipolar couplings for these derivatives. Good agreement was observed between the averaged calculated data and the experimental parameters. Interesting questions related to the interplay between X-ray crystallography and solid state NMR are raised and will be emphasized.

  1. Improvement/Maintenance and Reorientation as Central Features of Coping with Major Life Change and Loss: Contributions of Three Life-Span Theories

    ERIC Educational Resources Information Center

    Boerner, Kathrin; Jopp, Daniela

    2007-01-01

    This article focuses on the common and unique contributions of three major life-span theories in addressing improvement/maintenance and reorientation, which represent central processes of coping with major life change and loss. For this purpose, we review and compare the dual-process model of assimilative and accommodative coping, the model of…

  2. Hydride reorientation and its impact on ambient temperature mechanical properties of high burn-up irradiated and unirradiated recrystallized Zircaloy-2 nuclear fuel cladding with an inner liner

    NASA Astrophysics Data System (ADS)

    Auzoux, Q.; Bouffioux, P.; Machiels, A.; Yagnik, S.; Bourdiliau, B.; Mallet, C.; Mozzani, N.; Colas, K.

    2017-10-01

    Precipitation of radial hydrides in zirconium-based alloy cladding concomitant with the cooling of spent nuclear fuel during dry storage can potentially compromise cladding integrity during its subsequent handling and transportation. This paper investigates hydride reorientation and its impact on ductility in unirradiated and irradiated recrystallized Zircaloy-2 cladding with an inner liner (cladding for boiling water reactors) subjected to hydride reorientation treatments. Cooling from 400 °C, hydride reorientation occurs in recrystallized Zircaloy-2 with liner at a lower effective stress in irradiated samples (below 40 MPa) than in unirradiated specimens (between 40 and 80 MPa). Despite significant hydride reorientation, unirradiated recrystallized Zircaloy-2 with liner cladding containing ∼200 wppm hydrogen shows a high diametral strain at fracture (>15%) during burst tests at ambient temperature. This ductile behavior is due to (1) the lower yield stress of the recrystallized cladding materials in comparison to hydride fracture strength (corrected by the compression stress arising from the precipitation) and (2) the hydride or hydrogen-depleted zone as a result of segregation of hydrogen into the liner layer. In irradiated Zircaloy-2 with liner cladding containing ∼340 wppm hydrogen, the conservation of some ductility during ring tensile tests at ambient temperature after reorientation treatment at 400 °C with cooling rates of ∼60 °C/h is also attributed to the existence of a hydride-depleted zone. Treatments at lower cooling rates (∼6 °C/h and 0.6 °C/h) promote greater levels of hydrogen segregation into the liner and allow for increased irradiation defect annealing, both of which result in a significant increase in ductility. Based on this investigation, given the very low cooling rates typical of dry storage systems, it can be concluded that the thermal transients associated with dry storage should not degrade, and more likely should actually improve, ductility of recrystallized Zircaloy-2 cladding with inner liner with such hydrogen content.

  3. Rotational diffusion of nondipolar and charged solutes in alkyl-substituted imidazolium triflimides: effect of C2 methylation on solute rotation.

    PubMed

    Prabhu, Sugosh R; Dutt, G B

    2014-08-07

    Rotational diffusion of a nondipolar solute 2,5-dimethyl-1,4-dioxo-3,6-diphenylpyrrolo[3,4-c]pyrrole (DMDPP) and a charged solute rhodamine 110 (R110) has been investigated in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([BMIM][Tf2N]) and 1-butyl-2,3-dimethylimidazolium bis(trifluoromethylsulfonyl)imide ([BMMIM][Tf2N]) to understand the influence of the C2 methylation on solute rotation. The measured reorientation times of the nondipolar solute DMDPP are similar in both the ionic liquids and follow Stokes-Einstein-Debye hydrodynamic theory with slip hydrodynamics. In contrast, rotational diffusion of the charged solute R110 in [BMIM][Tf2N] obeys stick hydrodynamics due to specific interactions with the anion of the ionic liquid. Nevertheless, the intriguing result of this study is that the reorientation times of R110 in [BMMIM][Tf2N] deviate significantly from the predictions of stick hydrodynamics, especially at ambient temperatures. The solute-solvent boundary condition parameter Cobs, which is defined as the ratio of the measured reorientation time to the one calculated using the SED theory with stick boundary condition, for R110 is lower by a factor of 2 in [BMMIM][Tf2N] compared to [BMIM][Tf2N] at 298 K. Upon increasing the temperature, Cobs gradually increases and eventually matches with that obtained in [BMIM][Tf2N] at 348 K. It has been well established that methylation of the C2 position in [BMMIM][Tf2N] switches off the main hydrogen-bonding interaction between the anion and the cation, but increases the Coulombic interactions. As a consequence of the enhanced interionic interactions between the cation and anion of the ionic liquid, specific interactions between R110 and [Tf2N] diminish leading to the faster rotation of the solute. However, such an influence is not apparent in case of DMDPP as it does not experience specific interactions with either the cation or the anion of these ionic liquids.

  4. Paleomagnetic and oxygen isotopic evidence for long term diagenesis in radiolarian chert, Pindos Mountains, Greece

    NASA Astrophysics Data System (ADS)

    Baltuck, Miriam

    1987-02-01

    Paleomagnetics was used in an attempt to improve chronostratigraphy in the Middle and Upper Jurassic radiolarian chert and siliceous mudstone of the Pindos Zone, Greece. Remanent magnetism studies showed strong magnetic intensity but scattered orientation. Orientation of some pressure solution features in the radiolarities indicates their formation under horizontal pressure, a condition which in Pindos geologic history would only have occurred during early Cretaceous or Cenozoic tectonics, indicating very late diagenesis in these parts of the section. From time of deposition to later time at which diagenesis can be documented, the Earth's magnetic field would have reversed many times. Remagnetization during solution-precipitation steps of silica diagenesis could complicate the rock magnetics. Oxygen isotopic and major element analyses of radiolarite lithologies show a systematic variation of rate of silica diagenesis in different host lithologies, thus solution-precipitation would occur at widely differing times throughout the section lithologies. If the dissolution of the silica cement were physically to free magnetic material from an earlier orientation, the result could be a partial shift toward alignment with the ambient magnetic field. Alternatively, complete reorientation of particles could have occurred at varying times in different parts of the section as a function of host lithology. During the northward movement and clockwise rotation of the Apulian subplate (including Pindos) these different lithologies could completely reorient during different stages of silica diagenesis, locking the orientation of iron magnetic moments into alignment with the ambient magnetic field at time of precipitation to result in a strong intensity but scattered orientation of Pindos rock magnetics.

  5. Reorienting programme budgeting and marginal analysis (PBMA) towards disinvestment.

    PubMed

    Mortimer, Duncan

    2010-10-14

    Remarkable progress has been made over the past 40 years in developing rational, evidence-based mechanisms for the allocation of health resources. Much of this progress has centred on mechanisms for commissioning new medical devices and pharmaceuticals. The attention of fund-managers and policy-makers is only now turning towards development of mechanisms for decommissioning, disinvesting or redeploying resources from currently funded interventions. While Programme Budgeting and Marginal Analysis would seem well-suited to this purpose, past applications include both successes and failures in achieving disinvestment and resource release. Drawing on recent successes/failures in achieving disinvestment and resource release via PBMA, this paper identifies four barriers/enablers to disinvestment via PBMA: (i) specification of the budget constraint, (ii) scope of the programme budget, (iii) composition and role of the advisory group, and (iv) incentives for/against contributing to a 'shift list' of options for disinvestment and resource release. A number of modifications to the PBMA process are then proposed with the aim of reorienting PBMA towards disinvestment. The reoriented model is differentiated by four features: (i) hard budget constraint with budgetary pressure; (ii) programme budgets with broad scope but specific investment proposals linked to disinvestment proposals with similar input requirements; (iii) advisory/working groups that include equal representation of sectional interests plus additional members with responsibility for advocating in favour of disinvestment, (iv) 'shift lists' populated and developed prior to 'wish lists' and investment proposals linked to disinvestment proposals within a relatively narrow budget area. While the argument and evidence presented here suggest that the reoriented model will facilitate disinvestment and resource release, this remains an empirical question. Likewise, further research will be required to determine whether or not the re-oriented model sacrifices feasibility and acceptability to obtain its hypothesised greater emphasis on disinvestment.

  6. Comparison of Anion Reorientational Dynamics in MCB 9 H 10 and M 2 B 10 H 10 (M = Li, Na) via Nuclear Magnetic Resonance and Quasielastic Neutron Scattering Studies

    DOE PAGES

    Soloninin, Alexei V.; Dimitrievska, Mirjana; Skoryunov, Roman V.; ...

    2016-12-13

    The disordered phases of the 1-carba-closo-decaborates LiCB9H10 and NaCB9H10 exhibit the best solid-state ionic conductivities to date among all known polycrystalline competitors, likely facilitated in part by the highly orientationally mobile CB9H10- anions. We have undertaken both NMR and quasielastic neutron scattering (QENS) measurements to help characterize the monovalent anion reorientational mobilities and mechanisms associated with these two compounds and to compare their anion reorientational behaviors with those for the divalent B10H102- anions in the related Li2B10H10 and Na2B10H10 compounds. NMR data show that the transition from the low-T ordered to the high-T disordered phase for both LiCB9H10 and NaCB9H10more » is accompanied by a nearly two-orders-of-magnitude increase in the reorientational jump rate of CB9H10- anions. QENS measurements of the various disordered compounds indicate anion jump correlation frequencies on the order of 1010-1011 s-1 and confirm that NaCB9H10 displays jump frequencies about 60% to 120% higher than those for LiCB9H10 and Na2B10H10 at comparable temperatures. The Q-dependent quasielastic scattering suggests similar small-angular-jump reorientational mechanisms for the different disordered anions, changing from more uniaxial in character at lower temperatures to more multidimensional at higher temperatures, although still falling short of full three-dimensional rotational diffusion below 500 K within the nanosecond neutron window.« less

  7. Reorienting programme budgeting and marginal analysis (PBMA) towards disinvestment

    PubMed Central

    2010-01-01

    Background Remarkable progress has been made over the past 40 years in developing rational, evidence-based mechanisms for the allocation of health resources. Much of this progress has centred on mechanisms for commissioning new medical devices and pharmaceuticals. The attention of fund-managers and policy-makers is only now turning towards development of mechanisms for decommissioning, disinvesting or redeploying resources from currently funded interventions. While Programme Budgeting and Marginal Analysis would seem well-suited to this purpose, past applications include both successes and failures in achieving disinvestment and resource release. Discussion Drawing on recent successes/failures in achieving disinvestment and resource release via PBMA, this paper identifies four barriers/enablers to disinvestment via PBMA: (i) specification of the budget constraint, (ii) scope of the programme budget, (iii) composition and role of the advisory group, and (iv) incentives for/against contributing to a 'shift list' of options for disinvestment and resource release. A number of modifications to the PBMA process are then proposed with the aim of reorienting PBMA towards disinvestment. Summary The reoriented model is differentiated by four features: (i) hard budget constraint with budgetary pressure; (ii) programme budgets with broad scope but specific investment proposals linked to disinvestment proposals with similar input requirements; (iii) advisory/working groups that include equal representation of sectional interests plus additional members with responsibility for advocating in favour of disinvestment, (iv) 'shift lists' populated and developed prior to 'wish lists' and investment proposals linked to disinvestment proposals within a relatively narrow budget area. While the argument and evidence presented here suggest that the reoriented model will facilitate disinvestment and resource release, this remains an empirical question. Likewise, further research will be required to determine whether or not the re-oriented model sacrifices feasibility and acceptability to obtain its hypothesised greater emphasis on disinvestment. PMID:20942972

  8. The world is not flat: can people reorient using slope?

    PubMed

    Nardi, Daniele; Newcombe, Nora S; Shipley, Thomas F

    2011-03-01

    Studies of spatial representation generally focus on flat environments and visual input. However, the world is not flat, and slopes are part of most natural environments. In a series of 4 experiments, we examined whether humans can use a slope as a source of allocentric, directional information for reorientation. A target was hidden in a corner of a square, featureless enclosure tilted at a 5° angle. Finding it required using the vestibular, kinesthetic, and visual cues associated with the slope gradient. In Experiment 1, the overall sample performed above chance, showing that slope is sufficient for reorientation in a real environment. However, a sex difference emerged; men outperformed women by 1.4 SDs because they were more likely to use a slope-based strategy. In Experiment 2, attention was drawn to the slope, and participants were prompted to rely on it to solve the task; however, men still outperformed women, indicating a greater ability to use slope. In Experiment 3, we excluded the possibility that women's disadvantage was due to wearing heeled footwear. In Experiment 4, women required more time than men to identify the uphill direction of the slope gradient; this suggests that, in a bottom-up fashion, a perceptual or attentional difficulty underlies women's disadvantage in the ability to use slope and their decreased reliance on this cue. Overall, a bi-coordinate representation was used to find the goal: The target was encoded primarily with respect to the vertical axis and secondarily with respect to the orthogonal axis of the slope. 2011 APA, all rights reserved

  9. Tidal reorientation and the fracturing of Jupiter's moon Europa

    USGS Publications Warehouse

    McEwen, A.S.

    1986-01-01

    The most striking characteristic of Europa is the network of long linear albedo markings over the surface, suggestive of global-scale tectonic processes. Various explanations for the fractures have been proposed: Freezing and expansion of an early liquid water ocean1, planetary expansion due to dehydration of hydrated silicates2, localization by weak points in the crust generated by impacts3, and a combination of stresses due to planetary volume change and tidal distortions from orbital recession and orbital eccentricity4,5. Calculations by Yoder6 and Greenberg and Weidenschilling7 have shown that Europa may rotate slightly more rapidly than the synchronous rate, with a rotation period (reorientation through 360??) ranging from 20 to >103 yr if a liquid mantle is present, or up to 1010 yr if the satellite is essentially solid7. Helfen-stein and Parmentier8 modelled the stresses due to nonsynchronous rotation, and concluded that this could explain the long fractures in part of the anti-jovian hemisphere. In this note, I present a global map of lineaments with long arc lengths (>20?? or 550 km), and compare the lineament orientations to the tensile stress trajectories due to tidal distortions (changes in the lengths of three principal semiaxes) and to nonsynchronous rotation (longitudinal reorientation of two of the principal semiaxes). An excellent orthogonal fit to the lineaments is achieved by the stresses due to nonsynchronous rotation with the axis radial to Jupiter located 25?? east of its present position. This fit suggests that nonsynchronous rotation occurred at some time in Europa's history. ?? 1986 Nature Publishing Group.

  10. Room-temperature observation and current control of skyrmions in Pt/Co/Os/Pt thin films

    NASA Astrophysics Data System (ADS)

    Tolley, R.; Montoya, S. A.; Fullerton, E. E.

    2018-04-01

    We report the observation of room-temperature magnetic skyrmions in Pt/Co/Os/Pt thin-film heterostructures and their response to electric currents. The magnetic properties are extremely sensitive to inserting thin Os layers between the Co-Pt interface, resulting in reduced saturation magnetization, magnetic anisotropy, and Curie temperature. The observed skyrmions exist in a narrow temperature, applied-field and layer-thickness range near the spin-reorientation transition from perpendicular to in-plane magnetic anisotropy. The skyrmions have an average diameter of 2.3 μ m and transport measurements demonstrate these features can be displaced by means of spin-orbit torques with current densities as low as J =2 ×108A / m2 and display a skyrmion Hall effect.

  11. Variable structure control of spacecraft reorientation maneuvers

    NASA Technical Reports Server (NTRS)

    Sira-Ramirez, H.; Dwyer, T. A. W., III

    1986-01-01

    A Variable Structure Control (VSC) approach is presented for multi-axial spacecraft reorientation maneuvers. A nonlinear sliding surface is proposed which results in an asymptotically stable, ideal linear sliding motion of Cayley-Rodriques attitude parameters. By imposing a desired equivalent dynamics on the attitude parameters, the approach is devoid of optimal control considerations. The single axis case provides a design scheme for the multiple axes design problem. Illustrative examples are presented.

  12. Plastid sedimentation kinetics in roots of wild-type and starch-deficient mutants of Arabidopsis

    NASA Technical Reports Server (NTRS)

    MacCleery, S. A.; Kiss, J. Z.

    1999-01-01

    Sedimentation and movement of plastids in columella cells of the root cap were measured in seedlings of wild-type, a reduced starch mutant, and a starchless mutant of Arabidopsis. To assay for sedimentation, we used both linear measurements and the change of angle from the cell center as indices in vertical and reoriented plants with the aid of computer-assisted image analysis. Seedlings were fixed at short periods after reorientation, and plastid sedimentation correlated with starch content in the three strains of Arabidopsis. Amyloplasts of wild-type seedlings showed the greatest sedimentation, whereas plastids of the starchless mutant showed no significant sedimentation in the vertically grown and reoriented seedlings. Because previous research has shown that a full complement of starch is needed for full gravitropic sensitivity, this study correlates increased sensitivity with plastid sedimentation. However, although plastid sedimentation contributed to gravisensitivity, it was not required, because the gravitropic starchless mutant had plastids that did not sediment. This is the first study, to our knowledge, to measure plastid sedimentation in Arabidopsis roots after reorientation of seedlings. Taken together, the results of this study are consistent with the classic plastid-based and protoplast-based models of graviperception and suggest that multiple systems of perception exist in plant cells.

  13. Differences between appetitive and aversive reinforcement on reorientation in a spatial working memory task.

    PubMed

    Golob, Edward J; Taube, Jeffrey S

    2002-10-17

    Tasks using appetitive reinforcers show that following disorientation rats use the shape of an arena to reorient, and cannot distinguish two geometrically similar corners to obtain a reward, despite the presence of a prominent visual cue that provides information to differentiate the two corners. Other studies show that disorientation impairs performance on certain appetitive, but not aversive, tasks. This study evaluated whether rats would make similar geometric errors in a working memory task that used aversive reinforcement. We hypothesized that in a task that used aversive reinforcement rats that were initially disoriented would not reorient by arena shape and thus make similar geometric errors. Tests were performed in a rectangular arena having one polarizing cue. In the appetitive condition water consumption was the reward. The aversive condition was a water maze task with reinforcement provided by escape to a hidden platform. In the aversive condition rats returned to the reinforced corner significantly more often than in the dry condition, and did not favor the diagonally opposite corner. Results show that rats can use cues besides arena shape to reorient in an aversive reinforcement condition. These findings may also reflect different strategies, with an escape/homing strategy in the wet condition and a foraging strategy in the dry condition.

  14. Pacific tectonics: Eastern-Pacific "stationarity" of EPR and causative association with Equator

    NASA Astrophysics Data System (ADS)

    Bostrom, R. C.

    2003-04-01

    The fundamentals of present-day Pacific tectonics are observed to be: its N/S mirror-symmetry about the Equator, displayed by the major transforms; its E/W asymmetry, represented by the western motion of the world's largest plate, originating in the eastern Equatorial Pacific; and correspondingly, development of the globally most voluminous subduction, at the western Pacific margin. The configuration seen at present is maintained at a fundamental level. The maximum in convective upwelling develops as coalescing plumes in the Galapagos region in the eastern Pacific. This has been found (Lonsdale 1988; McGuire and Hilde 2002; Chen and Lin 2002) to produce steady westward propagation of the Nazca/Cocos axis. Continually renewed, it determines the orientation and locus of a quasi-stationary EPR, centered on the Equator. Magnetic dating of boundaries in satellite gravity images records the Cenozoic history of the EPR, namely re-orientation in consequence of slow counter-clockwise re-orientation of the Equator. Relative to the present, during Maastrichtian times both Equator and plate motion were aligned WNW, recorded paleomagnetically and by features in the western, older part of the Pacific crust. Material subducted at that time accumulated principally beneath the SE Asia margin. Its slow heating is believed to play a role in the deep-seated activity and back-arc spreading associated with latter-day convergence in that region. The mechanism primarily responsible for the Pacific regime may be that mantle convection is not immune, as is generally tacitly supposed, to the minute westward tilt (c. 0.36°) under which it takes place. The latter, now astronomically quantifiable without tidal identification, represents the attraction component of water and solid-Earth masses which averaged over unit day lags the direction of purely geocentric g. Under gravity minutely E/W asymmetric, convection as always promoting the most efficient dissipative configuration, favors disproportionately large surface-west displacement, maximum at the contemporary Equator (=west limb of EPR upwelling). Some conclusions are a), that it is no longer adequate to model global convection assuming that angular momentum is conserved internally; in reality a considerable part is exported, here measured by expansion of the lunar orbit; and b), that the tectonics of an Earth simultaneously under vigorous convection and in asynchronous rotation relative to the mass center of Kuiper's Earth-Moon double planet, differs fundamentally from the regime developing within a fictitious isolated planet.

  15. The Modulation of Exogenous Spatial Cueing on Spatial Stroop Interference: Evidence of a Set for "Cue-Target Event Segregation"

    ERIC Educational Resources Information Center

    Funes, Maria Jesus; Lupianez, Juan; Milliken, Bruce

    2008-01-01

    Two experiments are reported that test whether the modulation of exogenous cuing effects by the presence of a distractor at the location opposite the target (altering the time course of cueing effects, Lupianez et al., 1999, 2001) is due to the fast reorienting of attention or to a set for preventing the integration of the cue and the target…

  16. Two-dimensional nature of the active Brownian motion of catalytic microswimmers at solid and liquid interfaces

    NASA Astrophysics Data System (ADS)

    Dietrich, Kilian; Renggli, Damian; Zanini, Michele; Volpe, Giovanni; Buttinoni, Ivo; Isa, Lucio

    2017-06-01

    Colloidal particles equipped with platinum patches can establish chemical gradients in H2O2-enriched solutions and undergo self-propulsion due to local diffusiophoretic migration. In bulk (3D), this class of active particles swim in the direction of the surface heterogeneities introduced by the patches and consequently reorient with the characteristic rotational diffusion time of the colloids. In this article, we present experimental and numerical evidence that planar 2D confinements defy this simple picture. Instead, the motion of active particles both on solid substrates and at flat liquid-liquid interfaces is captured by a 2D active Brownian motion model, in which rotational and translational motion are constrained in the xy-plane. This leads to an active motion that does not follow the direction of the surface heterogeneities and to timescales of reorientation that do not match the free rotational diffusion times. Furthermore, 2D-confinement at fluid-fluid interfaces gives rise to a unique distribution of swimming velocities: the patchy colloids uptake two main orientations leading to two particle populations with velocities that differ up to one order of magnitude. Our results shed new light on the behavior of active colloids in 2D, which is of interest for modeling and applications where confinements are present.

  17. Noise amplification of plant gravisensing

    NASA Astrophysics Data System (ADS)

    Ma, Zhong; Hasenstein, Karl H.

    A common problem in sensory physiology is the detection of weak signals, such as that produced by the repositioning of statoliths (amyloplasts) in gravisensing cells, from a noisy background. As in other studied biological mechanosensory systems, it is conceivable that the gravisensing process may be amplified by stochastic resonance and nonlinear noise-assisted effects. We therefore investigated the possible dependency of gravisensing on vibrational or thermodynamic noise by examining the effect of external oscillation and temperature on the rate of gravitropic curvature in flax (Linum usitatissimum L.) roots. Roots were oscillated for 15 min prior to or during gravistimulation, either parallel or perpendicular to the root axis. The effect of oscillation was dependent on its direction as well as frequency and amplitude. Initial curvature was most effectively enhanced by vertical oscillations of 5 Hz and 0.5 mm amplitude prior to reorientation. Vertically oscillated roots reached half-maximal curvature 32 min after reorientation, about 18 min earlier than non-oscillated roots. The enhancing effect of vibration on curvature subsided with a half-time of about 20 min. The temperature dependency of the graviresponse indicated that thermodynamic noise also impacted gravity perception. For vibrations and temperature studies, the presentation times decreased almost 6-fold. Our data indicate that gravisensing may depend on or be enhanced by thermodynamic or mechanical noise.

  18. Observation of multiple dielectric relaxations in BaTiO3-Bi(Li1/3Ti2/3)O3 ceramics

    NASA Astrophysics Data System (ADS)

    Zhou, Changrong; Feteira, Antonio

    2017-11-01

    Dense (1 - x)BaTiO3- xBi(Li1/3Ti2/3)O3 ceramics were fabricated by the solid state reaction route. Powder X-ray diffraction analyses revealed an increase in the unit cell volume with increasing x and a change on the average crystal structure from tetragonal (space group P4mm) to cubic ( Pm\\bar{3}m ) at x > 0.10. Raman spectroscopy analyses corroborated a change of symmetry, but also showed the local structure for x > 0.10 to be inconsistent with the centrosymmetric ( Pm\\bar{3}m ) space group. The dielectric measurements revealed for the first time, to our knowledge, a double relaxor behaviour in a BaTiO3-based solid solution. Basically, with increasing x, the sharp ferroelectric anomaly at the Curie temperature ( T c) shifts towards lower temperatures until a relaxor-type response is observed, but simultaneously, another relaxation emerges above T c. The first arises from poor coupling between polar nanoregions, whereas the later obeys the Arrhenius Law and may be associated either with a defect-dipole reorientation or a Skanavi-type mechanism.

  19. NMR detection of pH-dependent histidine-water proton exchange reveals the conduction mechanism of a transmembrane proton channel.

    PubMed

    Hu, Fanghao; Schmidt-Rohr, Klaus; Hong, Mei

    2012-02-29

    The acid-activated proton channel formed by the influenza M2 protein is important for the life cycle of the virus. A single histidine, His37, in the M2 transmembrane domain (M2TM) is responsible for pH activation and proton selectivity of the channel. Recent studies suggested three models for how His37 mediates proton transport: a shuttle mechanism involving His37 protonation and deprotonation, a H-bonded imidazole-imidazolium dimer model, and a transporter model involving large protein conformational changes in synchrony with proton conduction. Using magic-angle-spinning (MAS) solid-state NMR spectroscopy, we examined the proton exchange and backbone conformational dynamics of M2TM in a virus-envelope-mimetic membrane. At physiological temperature and pH, (15)N NMR spectra show fast exchange of the imidazole (15)N between protonated and unprotonated states. To quantify the proton exchange rates, we measured the (15)N T(2) relaxation times and simulated them for chemical-shift exchange and fluctuating N-H dipolar fields under (1)H decoupling and MAS. The exchange rate is 4.5 × 10(5) s(-1) for Nδ1 and 1.0 × 10(5) s(-1) for Nε2, which are approximately synchronized with the recently reported imidazole reorientation. Binding of the antiviral drug amantadine suppressed both proton exchange and ring motion, thus interfering with the proton transfer mechanism. By measuring the relative concentrations of neutral and cationic His as a function of pH, we determined the four pK(a) values of the His37 tetrad in the viral membrane. Fitting the proton current curve using the charge-state populations from these pK(a)'s, we obtained the relative conductance of the five charge states, which showed that the +3 channel has the highest time-averaged unitary conductance. At physiologically relevant pH, 2D correlation spectra indicated that the neutral and cationic histidines do not have close contacts, ruling out the H-bonded dimer model. Moreover, a narrowly distributed nonideal helical structure coexists with a broadly distributed ideal helical conformation without interchange on the sub-10 ms time scale, thus excluding the transporter model in the viral membrane. These data support the shuttle mechanism of proton conduction, whose essential steps involve His-water proton exchange facilitated by imidazole ring reorientations. © 2011 American Chemical Society

  20. Efficient Reorientation Maneuvers for Spacecraft with Multiple Articulated Payloads

    NASA Technical Reports Server (NTRS)

    Mcclamroch, N. Harris

    1993-01-01

    A final report is provided which describes the research program during the period 3 Mar. 1992 to 3 Jun. 1993. A summary of the technical research questions that were studied and of the main results that were obtained is given. The specific outcomes of the research program, including both educational impacts as well as research publications, are listed. The research is concerned with efficient reorientation maneuvers for spacecraft with multiple articulated payloads.

  1. ISS Expedition 18 Synchronized Position Hold,Engage,Reorient,Experimental Satellites (SPHERES)

    NASA Image and Video Library

    2008-10-26

    ISS018-E-005214 (26 Oct. 2008) --- This close-up view shows three bowling-ball-sized free-flying satellites called Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) in the Destiny laboratory of the International Space Station. SPHERES were designed to test control algorithms for spacecraft by performing autonomous rendezvous and docking maneuvers inside the station. The results are important for multi-body control and in designing constellation and array spacecraft configurations.

  2. First principles and metadynamics study of the spin-reorientation transition in Fe/Au(001) films

    NASA Astrophysics Data System (ADS)

    Nagyfalusi, B.; Udvardi, L.; Szunyogh, L.

    2017-10-01

    Based on first principles calculations, we investigate the magnetic anisotropy and spin reorientation transition (SRT) for Fe n /Au(001) (n=2,3) films. The SRT occurs at three atomic layer of Fe in agreement with experiments due to competing on-site and two-site anisotropy. We also study the temperature dependence of the magnetic anisotropy energy (MAE) by means of metadynamics Monte Carlo simulations.

  3. Initiation of geyser during the resettlement of cryogenic liquid under impulsive reverse gravity acceleration in microgravity environment

    NASA Technical Reports Server (NTRS)

    Hung, R. J.; Shyu, K. L.

    1991-01-01

    The requirement to settle or to position liquid fluid over the outlet end of spacecraft propellant tank prior to main engine restart poses a microgravity fluid behavior problem. Resettlement or reorientation of liquid propellant can be accomplished by providing optimal acceleration to the spacecraft such that the propellant is reoriented over the tank outlet without any vapor entrainment, any excessive geysering, or any other undesirable fluid motion for the space fluid management under microgravity environment. The purpose of present study is to investigate most efficient technique for propellant resettling through the minimization of propellant usage and weight penalties. Comparison between the constant reverse gravity acceleration and impulsive reverse gravity acceleration to be used for the activation of propellant resettlement, it shows that impulsive reverse gravity thrust is superior to constant reverse gravity thrust for liquid reorientation in a reduced gravity environment.

  4. Periacetabular osteotomy: a review of swiss experience.

    PubMed

    Büchler, Lorenz; Beck, Martin

    2014-12-01

    Symptomatic dysplasia of the hip and acetabular retroversion are possible causes of osteoarthritis in the young adult. Surgical management with reorientation of the acetabulum allows causal therapy of the deformity and preservation of the native hip joint. The Ganz' periacetabular osteotomy permits a free 3-dimensional reorientation of the acetabulum and respects the blood supply of the acetabular fragment. The posterior column remains intact with a stable fixation of the acetabular fragment and a preserved shape of the true pelvis. There is a significant learning curve with severe complications in up to 30 % of cases. Good results can be expected in the long-term follow-up if performed with correct indication at young age in hips with preserved joint cartilage and proper reorientation of the acetabular fragment. Overall survivorship is superior to the natural course of hip dysplasia with a preserved hip joint in 61 % after 20 years.

  5. Hydraulic fracture orientation and production/injection induced reservoir stress changes in diatomite waterfloods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wright, C.A.; Conant, R.A.; Golich, G.M.

    1995-12-31

    This paper summarizes the (preliminary) findings from extensive field studies of hydraulic fracture orientation in diatomite waterfloods and related efforts to monitor the induced surface subsidence. Included are case studies from the Belridge and Lost Hills diatomite reservoirs. The primary purpose of the paper is to document a large volume of tiltmeter hydraulic fracture orientation data that demonstrates waterflood-induced fracture reorientation--a phenomenon not previously considered in waterflood development planning. Also included is a brief overview of three possible mechanisms for the observed waterflood fracture reorientation. A discussion section details efforts to isolate the operative mechanism(s) from the most extensive casemore » study, as well as suggesting a possible strategy for detecting and possibly mitigating some of the adverse effects of production/injection induced reservoir stress changes--reservoir compaction and surface subsidence as well as fracture reorientation.« less

  6. Paleomagnetic reorientation of San Andreas Fault Observatory at Depth (SAFOD) core

    USGS Publications Warehouse

    Pares, J.M.; Schleicher, A.M.; van der Pluijm, B.A.; Hickman, S.

    2008-01-01

    We present a protocol for using paleomagnetic analysis to determine the absolute orientation of core recovered from the SAFOD borehole. Our approach is based on determining the direction of the primary remanent magnetization of a spot core recovered from the Great Valley Sequence during SAFOD Phase 2 and comparing its direction to the expected reference field direction for the Late Cretaceous in North America. Both thermal and alternating field demagnetization provide equally resolved magnetization, possibly residing in magnetite, that allow reorientation. Because compositionally similar siltstones and fine-grained sandstones were encountered in the San Andreas Fault Zone during Stage 2 rotary drilling, we expect that paleomagnetic reorientation will yield reliable core orientations for continuous core acquired from directly within and adjacent to the San Andreas Fault during SAFOD Phase 3, which will be key to interpretation of spatial properties of these rocks. Copyright 2008 by the American Geophysical Union.

  7. Experimental Study on the Anisotropic Stress-Strain Behavior of Polycrystalline Ni-Mn-Ga in Directional Solidification

    NASA Astrophysics Data System (ADS)

    Teng, Yao; Shi, Tao; Zhu, Yuping; Li, Zongbin; Deng, Tao; Bai, Guonan

    2016-03-01

    A polycrystalline Ni-Mn-Ga ferromagnetic shape memory alloy produced by directional solidification is the subject of this research paper. The compressive stress-strain curves of the material for different cutting angles to the solidification direction are tested. The martensite Young's modulus, macroscopic reorientation strain, and phase transition critical stress are analyzed experimentally. The results show that mechanical behaviors in the loading-unloading cycle of the material present nonlinear and anisotropic characteristics, which are all closely related to the material's orientation to the solidification direction. The martensite Young's modulus, macroscopic reorientation strain, and phase transition critical stress achieve maximum values in the solidification direction. A 50° orientation to the solidification direction is the cut-off direction of the mechanical properties, where the martensite Young's modulus and reorientation start critical stress reach minimum values. The present study is expected to provide sound guidance for practical applications.

  8. Longitudinal change in the neural bases of adolescent social self-evaluations: effects of age and pubertal development.

    PubMed

    Pfeifer, Jennifer H; Kahn, Lauren E; Merchant, Junaid S; Peake, Shannon J; Veroude, Kim; Masten, Carrie L; Lieberman, Matthew D; Mazziotta, John C; Dapretto, Mirella

    2013-04-24

    Self-evaluations undergo significant transformation during early adolescence, developing in parallel with the heightened complexity of teenagers' social worlds. Intuitive theories of adolescent development, based in part on animal work, suggest that puberty is associated with neural-level changes that facilitate a "social reorientation" (Nelson et al., 2005). However, direct tests of this hypothesis using neuroimaging are limited in humans. This longitudinal fMRI study examined neurodevelopmental trajectories associated with puberty, self-evaluations, and the presumed social reorientation during the transition from childhood to adolescence. Participants (N = 27, mean age = 10.1 and 13.1 years at time points one and two, respectively) engaged in trait evaluations of two targets (the self and a familiar fictional other), across two domains of competence (social and academic). Responses in ventromedial PFC increased with both age and pubertal development during self-evaluations in the social domain, but not in the academic domain. These results suggest that changes in social self-evaluations are intimately connected with biology, not just peer contexts, and provide important empirical support for the relationship between neurodevelopment, puberty, and social functioning.

  9. Brassinosteroid control of shoot gravitropism interacts with ethylene and depends on auxin signaling components.

    PubMed

    Vandenbussche, Filip; Callebert, Pieter; Zadnikova, Petra; Benkova, Eva; Van Der Straeten, Dominique

    2013-01-01

    To reach favorable conditions for photosynthesis, seedlings grow upward when deprived of light upon underground germination. To direct their growth, they use their negative gravitropic capacity. Negative gravitropism is under tight control of multiple hormones. By counting the number of standing plants in a population or by real time monitoring of the reorientation of gravistimulated seedlings of Arabidopsis thaliana, we evaluated the negative gravitropism of ethylene or brassinosteroid (BR) treated plants. Meta-analysis of transcriptomic data on AUX/IAA genes was gathered, and subsequent mutant analysis was performed. Ethylene and BR have opposite effects in regulating shoot gravitropism. Lack of BR enhances gravitropic reorientation in 2-d-old seedlings, whereas ethylene does not. Lack of ethylene signaling results in enhanced BR sensitivity. Ethylene and BRs regulate overlapping sets of AUX/IAA genes. BRs regulate a wider range of auxin signaling components than ethylene. Upward growth in seedlings depends strongly on the internal hormonal balance. Endogenous ethylene stimulates, whereas BRs reduce negative gravitropism in a manner that depends on the function of different, yet overlapping sets of auxin signaling components.

  10. Effects of inversion on plastid position and gravitropism in Ceratodon protonemata

    NASA Technical Reports Server (NTRS)

    Schwuchow, J.; Sack, F. D.

    1993-01-01

    When dark-grown tip cells of protonemata of the moss Ceratodon purpureus are turned to the horizontal, plastids first sediment towards gravity in a specific zone and then the tip curves upward. To determine whether gravitropism and plastid sedimentation occur in other orientations, protonemata were reoriented to angles other than 90 degrees. Qualitative and quantitative light microscopic observations show that plastid sedimentation along the cell axis occurs in both upright and inverted cells. However, only some plastids fall and sedimentation is incomplete; plastids remain distributed throughout the length of the cell, and those plastids that sediment do not fall all the way to the bottom of the cell. Tip cells are gravitropic regardless of stimulation angle, and as in higher plants, the maximal rate of initial curvature is in response to a 120 degrees reorientation. Infrared videomicroscopy, time-lapse studies of living, inverted protonemata indicate that amyloplast sedimentation precedes upward curvature. Together, these data further support (i) the hypothesis that amyloplast sedimentation functions in gravitropic sensing in these cells, and (ii) the idea that gravity affected the evolution of cell organization.

  11. Statics and dynamics of free and hydrogen-bonded OH groups at the air/water interface.

    PubMed

    Vila Verde, Ana; Bolhuis, Peter G; Campen, R Kramer

    2012-08-09

    We use classical atomistic molecular dynamics simulations of two water models (SPC/E and TIP4P/2005) to investigate the orientation and reorientation dynamics of two subpopulations of OH groups belonging to water molecules at the air/water interface at 300 K: those OH groups that donate a hydrogen bond (called "bonded") and those that do not (called "free"). Free interfacial OH groups reorient in two distinct regimes: a fast regime from 0 to 1 ps and a slow regime thereafter. Qualitatively similar behavior was reported by others for free OH groups near extended hydrophobic surfaces. In contrast, the net reorientation of bonded OH groups occurs at a rate similar to that of bulk water. This similarity in reorientation rate results from compensation of two effects: decreasing frequency of hydrogen-bond breaking/formation (i.e., hydrogen-bond exchange) and faster rotation of intact hydrogen bonds. Both changes result from the decrease in density at the air/water interface relative to the bulk. Interestingly, because of the presence of capillary waves, the slowdown of hydrogen-bond exchange is significantly smaller than that reported for water near extended hydrophobic surfaces, but it is almost identical to that reported for water near small hydrophobic solutes. In this sense water at the air/water interface has characteristics of water of hydration of both small and extended hydrophobic solutes.

  12. Psychological symptoms and spatial orientation during the first 3 months after acute unilateral vestibular lesion.

    PubMed

    Gómez-Alvarez, Fatima B; Jáuregui-Renaud, Kathrine

    2011-02-01

    We undertook this study to assess the correlation between the results of simple tests of spatial orientation and the occurrence of common psychological symptoms during the first 3 months after an acute, unilateral, peripheral, vestibular lesion. Ten vestibular patients were selected and accepted to participate in the study. During a 3-month follow-up, we recorded the static visual vertical (VV), the estimation error of reorientation in the yaw plane and the responses to a standardized questionnaire of balance symptoms, the Dizziness Handicap Inventory (DHI), the depersonalization/derealization inventory by Cox and Swinson (DD), the Dissociative Experiences Scale (DES), the 12-item General Health Questionnaire (GHQ-12), the Zung Instrument for Anxiety Disorders and the Hamilton Depression Rating Scale. At week 1, all patients showed a VV >2° and failed to reorient themselves effectively. They reported several balance symptoms and handicap as well as DD symptoms, including attention/concentration difficulties; 80% of the patients had a Hamilton score ≥8. At this time the balance symptom score correlated with the DHI. After 3 months, all scores decreased. Multiple regression analysis of the differences from baseline showed that the DD score difference was related to the difference on the balance score, the reorientation error and the DHI score (p <0.01). No other linear relationships were observed (p >0.5). During the acute phase of a unilateral, peripheral, vestibular lesion, patients may show poor spatial orientation concurrent with DD symptoms including attention/concentration difficulties, and somatic depression symptoms. After vestibular rehabilitation, DD symptoms decrease as the spatial orientation improves, even if somatic symptoms of depression persist. Copyright © 2011 IMSS. Published by Elsevier Inc. All rights reserved.

  13. Conformational flexibility of arginine-82 as source for the heterogeneous and pH-dependent kinetics of the primary proton transfer step in the bacteriorhodopsin photocycle: An electrostatic model

    NASA Astrophysics Data System (ADS)

    Scharnagl, Christina; Fischer, Sighart F.

    1996-11-01

    We use equilibrium thermodynamic concepts to relate protein conformational and protonation substates and their pH-dependent population to kinetic schemes for the rise of the M intermediate in the photocycle of bacteriorhodopsin. Conformational flexibility of arginine R82 is described by a two-state model. The analysis accounts for the electrostatic coupling between its orientation and hydrogen ion titration and presents a structural basis for the linkage between the protonation states of the primary proton acceptor, aspartate D85, and the extracellular release group, glutamate E204. We find that the charge state of D85 is a significant determinant for the orientation of R82. The molecular model predicts the following: the primary proton transfer to D85 can be described by a kinetic scheme with two heterogeneous substates. They control the event with different activation parameters due to the reorientation of R82 away from the chromophore binding site. Their population depends on the external pH and the proton exchange equilibrium between the membrane buried residues and the bulk aqueous solvent. Proton transfer in the physiologic pH range is strongly activated and followed by the reorientation of R82 which shifts the equilibrium toward complete transfer. In the alkaline pH region a different mechanism operates, which involves the increased population of a substate with already reoriented R82 as a consequence of the deprotonation of E204, leading to accelerated proton transfer. Assuming full proton exchange equilibrium with the bulk water on the millisecond time scale leads to an increased population of substates which are non-productive for proton transfer.

  14. Synchronized Position Hold, Engage, Reorient, Experimental Satellites

    NASA Technical Reports Server (NTRS)

    Miller, David W.; Wilson, Edward; How, Jonathan; Sanenz-Otero, Alvar; Chamitoff, Gregory

    2009-01-01

    Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) are bowling-ball sized spherical satellites. They will be used inside the space station to test a set of well-defined instructions for spacecraft performing autonomous rendezvous and docking maneuvers. Three free-flying spheres will fly within the cabin of the station, performing flight formations. Each satellite is self-contained with power, propulsion, computers and navigation equipment. The results are important for satellite servicing, vehicle assembly and formation flying spacecraft configurations. SPHERES is a testbed for formation flying by satellites, the theories and calculations that coordinate the motion of multiple bodies maneuvering in microgravity. To achieve this inside the ISS cabin, bowling-ball-sized spheres perform various maneuvers (or protocols), with one to three spheres operating simultaneously . The Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) experiment will test relative attitude control and station-keeping between satellites, re-targeting and image plane filling maneuvers, collision avoidance and fuel balancing algorithms, and an array of geometry estimators used in various missions. SPHERES consists of three self-contained satellites, which are 18 sided polyhedrons that are 0.2 meter in diameter and weigh 3.5 kilograms. Each satellite contains an internal propulsion system, power, avionics, software, communications, and metrology subsystems. The propulsion system uses CO2, which is expelled through the thrusters. SPHERES satellites are powered by AA batteries. The metrology subsystem provides real-time position and attitude information. To simulate ground station-keeping, a laptop will be used to transmit navigational data and formation flying algorithms. Once these data are uploaded, the satellites will perform autonomously and hold the formation until a new command is given.

  15. Self-Assembly, Surface Activity and Structure of n-Octyl-β-D-thioglucopyranoside in Ethylene Glycol-Water Mixtures

    PubMed Central

    Ruiz, Cristóbal Carnero; Molina-Bolívar, José Antonio; Hierrezuelo, José Manuel; Liger, Esperanza

    2013-01-01

    The effect of the addition of ethylene glycol (EG) on the interfacial adsorption and micellar properties of the alkylglucoside surfactant n-octyl-β-d-thioglucopyranoside (OTG) has been investigated. Critical micelle concentrations (cmc) upon EG addition were obtained by both surface tension measurements and the pyrene 1:3 ratio method. A systematic increase in the cmc induced by the presence of the co-solvent was observed. This behavior was attributed to a reduction in the cohesive energy of the mixed solvent with respect to pure water, which favors an increase in the solubility of the surfactant with EG content. Static light scattering measurements revealed a decrease in the mean aggregation number of the OTG micelles with EG addition. Moreover, dynamic light scattering data showed that the effect of the surfactant concentration on micellar size is also controlled by the content of the co-solvent in the system. Finally, the effect of EG addition on the microstructure of OTG micelles was investigated using the hydrophobic probe Coumarin 153 (C153). Time-resolved fluorescence anisotropy decay curves of the probe solubilized in micelles were analyzed using the two-step model. The results indicate a slight reduction of the average reorientation time of the probe molecule with increasing EG in the mixed solvent system, thereby suggesting a lesser compactness induced by the presence of the co-solvent. PMID:23385232

  16. Self-assembly, surface activity and structure of n-octyl-β-D-thioglucopyranoside in ethylene glycol-water mixtures.

    PubMed

    Ruiz, Cristóbal Carnero; Molina-Bolívar, José Antonio; Hierrezuelo, José Manuel; Liger, Esperanza

    2013-02-05

    The effect of the addition of ethylene glycol (EG) on the interfacial adsorption and micellar properties of the alkylglucoside surfactant n-octyl-β-D-thioglucopyranoside (OTG) has been investigated. Critical micelle concentrations (cmc) upon EG addition were obtained by both surface tension measurements and the pyrene 1:3 ratio method. A systematic increase in the cmc induced by the presence of the co-solvent was observed. This behavior was attributed to a reduction in the cohesive energy of the mixed solvent with respect to pure water, which favors an increase in the solubility of the surfactant with EG content. Static light scattering measurements revealed a decrease in the mean aggregation number of the OTG micelles with EG addition. Moreover, dynamic light scattering data showed that the effect of the surfactant concentration on micellar size is also controlled by the content of the co-solvent in the system. Finally, the effect of EG addition on the microstructure of OTG micelles was investigated using the hydrophobic probe Coumarin 153 (C153). Time-resolved fluorescence anisotropy decay curves of the probe solubilized in micelles were analyzed using the two-step model. The results indicate a slight reduction of the average reorientation time of the probe molecule with increasing EG in the mixed solvent system, thereby suggesting a lesser compactness induced by the presence of the co-solvent.

  17. Decentralizing Centralized Control: Reorienting a Fundamental Tenet for Resilient Air Operation

    DTIC Science & Technology

    2008-05-22

    Forward Air Controller FBIS Foreign Broadcast Information Service FCC Functional Component Commander FM Field Manual GBU - 39 Guided Bomb Unit - 39...Diameter Bomb ( GBU - 39 ) TEG Test and Evaluation Group TST Time Sensitive Target UAV Unmanned Aerial Vehicle USAF United States Air Force USAFWS United...www.afmc.af.mil/news/story.asp?id=123017916 (accessed November 11, 2007). Recent fielding of the GBU - 39 , Small Diameter Bomb (SDB), enables a

  18. SPHERES test

    NASA Image and Video Library

    2013-07-05

    ISS036-E-015549 (5 July 2013) --- In the International Space Station’s Kibo laboratory, NASA astronaut Chris Cassidy, Expedition 36 flight engineer, watches as he devotes some time with the long-running SPHERES experiment, also known as Synchronized Position Hold Engage and Reorient Experimental Satellites. The experiment is run in conjunction with students who program bowling ball-sized satellites using algorithms. The free-floating satellites are programmed to perform maneuvers potentially influencing the design of future missions.

  19. `Membership Has Its Privileges': Status Incentives and Categorical Inequality in Education

    PubMed Central

    Domina, Thurston; Penner, Andrew M.; Penner, Emily K.

    2015-01-01

    Prizes – formal systems that publicly allocate rewards for exemplary behavior – play an increasingly important role in a wide array of social settings, including education. In this paper, we evaluate a prize system designed to boost achievement at two high schools by assigning students color-coded ID cards based on a previously low stakes test. Average student achievement on this test increased in the ID card schools beyond what one would expect from contemporaneous changes in neighboring schools. However, regression discontinuity analyses indicate that the program created new inequalities between students who received low-status and high-status ID cards. These findings indicate that status-based incentives create categorical inequalities between prize winners and others even as they reorient behavior toward the goals they reward. PMID:27213170

  20. Enabling health systems transformation: what progress has been made in re-orienting health services?

    PubMed

    Wise, Marilyn; Nutbeam, Don

    2007-01-01

    The Ottawa Charter has been remarkably influential in guiding the development of the goals and concepts of health promotion, and in shaping global public health practice in the past 20 years. However, of the five action areas identified in the Ottawa Charter, it appears that there has been little systematic attention to the challenge of re-orienting health services, and less than optimal progress in practice. The purposes of re-orienting health services as proposed in the Ottawa Charter were to achieve a better balance in investment between prevention and treatment, and to include a focus on population health outcomes alongside the focus on individual health outcomes. However, there is little evidence that a re-orientation of health services in these terms has occurred systematically anywhere in the world. This is in spite of the fact that direct evidence of the need to re-orient health services and of the potential benefits of doing so has grown substantially since 1986. Patient education, preventive care (screening, immunisation), and organisational and environmental changes by health organisations have all been found to have positive health and environmental outcomes. However, evidence of effectiveness has not been sufficient, on its own, to sway community preferences and political decisions. The lack of progress points to the need for significant re-thinking of the approaches we have adopted to date. The paper proposes a number of ways forward. These include working effectively in partnership with the communities we want to serve to mobilise support for change, and to reinforce this by working more effectively at influencing broader public opinion through the media. The active engagement of clinical health professionals is also identified as crucial to achieving sustainable change. Finally we recognize that by working in partnership with like-minded advocacy organizations, the IUHPE could put its significant knowledge and experience to work in leading action to transform health care systems to make a major contribution to the improvement of public health.

  1. Pluto followed its heart: reorientation and faulting of Pluto due to volatile loading in Sputnik Planum

    NASA Astrophysics Data System (ADS)

    Tuttle Keane, James; Matsuyama, Isamu; Kamata, Shunichi; Steckloff, Jordan

    2016-10-01

    The New Horizons flyby of Pluto revealed the dwarf planet to be a strikingly diverse, geologically active world. Perhaps the most intriguing feature on the New Horizons encounter hemisphere is Sputnik Planum—a 1000 km diameter, probable impact basin, filled with several kilometers of actively convecting volatile ices (N2, CH4, CO). One salient characteristic of Sputnik Planum is its curious alignment with the Pluto-Charon tidal axis. The alignment of large geologic features with principal axis of inertia (such as the tidal axis) is the hallmark of global reorientation, i.e. true polar wander. Here we show that the present location of Sputnik Planum is a natural consequence of loading of 1-2 km of volatile ices within the Sputnik Planum basin. Larger volatile ice thicknesses (like those inferred from studies of ice convection within Sputnik Planum) betray an underlying negative gravity anomaly associated with the basin. As Pluto reoriented in response to the loading of volatile ices within Sputnik Planum, stresses accumulated within the lithosphere (as each geographic location experiences a change in tidal/rotational potential). These reorientation stresses, coupled with loading stresses, and stresses from the freezing of a subsurface ocean resulted in the fracturing of Pluto's lithosphere in a characteristic, global pattern of extensional faults. Our predicted pattern of extensional faults due to this reorientation closely replicates the observed distribution of faults on Pluto (more so than global expansion, orbit migration, de-spinning, or loading alone). Sputnik Planum likely formed ~60° northwest of its present location, and was loaded with volatile ices over millions of years due to seasonal volatile transport cycles. This result places Pluto in a truly unique category of planetary bodies where volatiles are not only controlling surface geology and atmospheric processes, but they are also directly controlling the orientation of the entire dwarf planet. Pluto's past, present, and future orientation is controlled by complicated feedbacks between volatile transport, insolation, and interior structure.

  2. Fragmented Perception: Slower Space-Based but Faster Object-Based Attention in Recent-Onset Psychosis with and without Schizophrenia

    PubMed Central

    Smid, Henderikus G. O. M.; Bruggeman, Richard; Martens, Sander

    2013-01-01

    Background Schizophrenia is associated with impairments of the perception of objects, but how this affects higher cognitive functions, whether this impairment is already present after recent onset of psychosis, and whether it is specific for schizophrenia related psychosis, is not clear. We therefore tested the hypothesis that because schizophrenia is associated with impaired object perception, schizophrenia patients should differ in shifting attention between objects compared to healthy controls. To test this hypothesis, a task was used that allowed us to separately observe space-based and object-based covert orienting of attention. To examine whether impairment of object-based visual attention is related to higher order cognitive functions, standard neuropsychological tests were also administered. Method Patients with recent onset psychosis and normal controls performed the attention task, in which space- and object-based attention shifts were induced by cue-target sequences that required reorienting of attention within an object, or reorienting attention between objects. Results Patients with and without schizophrenia showed slower than normal spatial attention shifts, but the object-based component of attention shifts in patients was smaller than normal. Schizophrenia was specifically associated with slowed right-to-left attention shifts. Reorienting speed was significantly correlated with verbal memory scores in controls, and with visual attention scores in patients, but not with speed-of-processing scores in either group. Conclusions deficits of object-perception and spatial attention shifting are not only associated with schizophrenia, but are common to all psychosis patients. Schizophrenia patients only differed by having abnormally slow right-to-left visual field reorienting. Deficits of object-perception and spatial attention shifting are already present after recent onset of psychosis. Studies investigating visual spatial attention should take into account the separable effects of space-based and object-based shifting of attention. Impaired reorienting in patients was related to impaired visual attention, but not to deficits of processing speed and verbal memory. PMID:23536901

  3. Fragmented perception: slower space-based but faster object-based attention in recent-onset psychosis with and without Schizophrenia.

    PubMed

    Smid, Henderikus G O M; Bruggeman, Richard; Martens, Sander

    2013-01-01

    Schizophrenia is associated with impairments of the perception of objects, but how this affects higher cognitive functions, whether this impairment is already present after recent onset of psychosis, and whether it is specific for schizophrenia related psychosis, is not clear. We therefore tested the hypothesis that because schizophrenia is associated with impaired object perception, schizophrenia patients should differ in shifting attention between objects compared to healthy controls. To test this hypothesis, a task was used that allowed us to separately observe space-based and object-based covert orienting of attention. To examine whether impairment of object-based visual attention is related to higher order cognitive functions, standard neuropsychological tests were also administered. Patients with recent onset psychosis and normal controls performed the attention task, in which space- and object-based attention shifts were induced by cue-target sequences that required reorienting of attention within an object, or reorienting attention between objects. Patients with and without schizophrenia showed slower than normal spatial attention shifts, but the object-based component of attention shifts in patients was smaller than normal. Schizophrenia was specifically associated with slowed right-to-left attention shifts. Reorienting speed was significantly correlated with verbal memory scores in controls, and with visual attention scores in patients, but not with speed-of-processing scores in either group. deficits of object-perception and spatial attention shifting are not only associated with schizophrenia, but are common to all psychosis patients. Schizophrenia patients only differed by having abnormally slow right-to-left visual field reorienting. Deficits of object-perception and spatial attention shifting are already present after recent onset of psychosis. Studies investigating visual spatial attention should take into account the separable effects of space-based and object-based shifting of attention. Impaired reorienting in patients was related to impaired visual attention, but not to deficits of processing speed and verbal memory.

  4. Characterization of poly(2-hydroxyethyl methacrylate) (PHEMA) contact lens using the Langmuir monolayer technique.

    PubMed

    Nogueira, N; Conde, O; Miñones, M; Trillo, J M; Miñones, J

    2012-11-01

    The behavior of poly(2-hydroxyethyl methacrylate) (PHEMA) polymer monolayer spread on water was studied under various experimental conditions. The influence of subphase pH and temperature, compression speed, elapsed time from the deposit of the monolayer and the recording of the surface pressure-area (π-A) isotherms, as well as the number of polymer molecules deposited at the air/water surface (surface concentration) was studied. The obtained results show that PHEMA exhibits a very stable monolayer given that it is unaffected by modifications in the majority of these variables. Only the elapsed time between the spreading of the monolayer and the beginning of compression causes a small change in the π-A isotherms that consists in an increase in the area occupied by the film. This is attributed to the greater unfolding with time of the polymer's monomers at the air/water interface. The plateau that appears on π-A curves of the PHEMA monolayer is attributed to the reorientation of their hydroxyethyl polar groups through their C-O-C bonds, as well as to the reorientation of the ethylene (CH(2)) groups that link the monomers, which provokes a folding of the polymer's chains causing an accordion configuration. The existence of this structure is confirmed by the presence of numerous noise peaks in the relative thickness versus time curve corresponding to this region. In the same fashion, the images observed from Brewster angle microscopy (BAM) reveal the existence of light-dark "bands" relative to the different regions of this particular structure. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Involuntary Capture and Voluntary Reorienting of Attention Decline in Middle-Aged and Old Participants

    PubMed Central

    Correa-Jaraba, Kenia S.; Cid-Fernández, Susana; Lindín, Mónica; Díaz, Fernando

    2016-01-01

    The main aim of this study was to examine the effects of aging on event-related brain potentials (ERPs) associated with the automatic detection of unattended infrequent deviant and novel auditory stimuli (Mismatch Negativity, MMN) and with the orienting to these stimuli (P3a component), as well as the effects on ERPs associated with reorienting to relevant visual stimuli (Reorienting Negativity, RON). Participants were divided into three age groups: (1) Young: 21–29 years old; (2) Middle-aged: 51–64 years old; and (3) Old: 65–84 years old. They performed an auditory-visual distraction-attention task in which they were asked to attend to visual stimuli (Go, NoGo) and to ignore auditory stimuli (S: standard, D: deviant, N: novel). Reaction times (RTs) to Go visual stimuli were longer in old and middle-aged than in young participants. In addition, in all three age groups, longer RTs were found when Go visual stimuli were preceded by novel relative to deviant and standard auditory stimuli, indicating a distraction effect provoked by novel stimuli. ERP components were identified in the Novel minus Standard (N-S) and Deviant minus Standard (D-S) difference waveforms. In the N-S condition, MMN latency was significantly longer in middle-aged and old participants than in young participants, indicating a slowing of automatic detection of changes. The following results were observed in both difference waveforms: (1) the P3a component comprised two consecutive phases in all three age groups—an early-P3a (e-P3a) that may reflect the orienting response toward the irrelevant stimulation and a late-P3a (l-P3a) that may be a correlate of subsequent evaluation of the infrequent unexpected novel or deviant stimuli; (2) the e-P3a, l-P3a, and RON latencies were significantly longer in the Middle-aged and Old groups than in the Young group, indicating delay in the orienting response to and the subsequent evaluation of unattended auditory stimuli, and in the reorienting of attention to relevant (Go) visual stimuli, respectively; and (3) a significantly smaller e-P3a amplitude in Middle-aged and Old groups, indicating a deficit in the orienting response to irrelevant novel and deviant auditory stimuli. PMID:27065004

  6. Efficient reorientation of a deformable body in space: A free-free beam example

    NASA Technical Reports Server (NTRS)

    Kolmanovsky, Ilya V.; Mcclamroch, N. Harris

    1993-01-01

    It is demonstrated that the planar reorientation of a free-free beam in zero gravity space can be accomplished by periodically changing the shape of the beam using internal actuators. A control scheme is proposed in which electromechanical actuators excite the flexible motion of the beam so that it rotates in the desired manner with respect to a fixed inertial reference. The results can be viewed as an extension of previous work to a distributed parameter case.

  7. Achieving giant magnetically induced reorientation of martensitic variants in magnetic shape-memory Ni-Mn-Ga Films by microstructure engineering.

    PubMed

    Ranzieri, Paolo; Campanini, Marco; Fabbrici, Simone; Nasi, Lucia; Casoli, Francesca; Cabassi, Riccardo; Buffagni, Elisa; Grillo, Vincenzo; Magén, Cesar; Celegato, Federica; Barrera, Gabriele; Tiberto, Paola; Albertini, Franca

    2015-08-26

    Giant magnetically induced twin variant reorientation, comparable in intensity with bulk single crystals, is obtained in epitaxial magnetic shape-memory thin films. It is found to be tunable in intensity and spatial response by the fine control of microstructural patterns at the nanoscopic and microscopic scales. A thorough experimental study (including electron holography) allows a multiscale comprehension of the phenomenon. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Modulation of attentional networks by food-related disinhibition.

    PubMed

    Hege, Maike A; Stingl, Krunoslav T; Veit, Ralf; Preissl, Hubert

    2017-07-01

    The risk of weight gain is especially related to disinhibition, which indicates the responsiveness to external food stimuli with associated disruptions in eating control. We adapted a food-related version of the attention network task and used functional magnetic resonance imaging to study the effects of disinhibition on attentional networks in 19 normal-weight participants. High disinhibition scores were associated with a rapid reorienting response to food pictures after invalid cueing and with an enhanced alerting effect of a warning cue signalizing the upcoming appearance of a food picture. Imaging data revealed activation of a right-lateralized ventral attention network during reorienting. The faster the reorienting and the higher the disinhibition score, the less activation of this network was observed. The alerting contrast showed activation in visual, temporo-parietal and anterior sites. These modulations of attentional networks by food-related disinhibition might be related to an attentional bias to energy dense and palatable food and increased intake of food in disinhibited individuals. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Reorientation of Sputnik Planitia implies a subsurface ocean on Pluto.

    PubMed

    Nimmo, F; Hamilton, D P; McKinnon, W B; Schenk, P M; Binzel, R P; Bierson, C J; Beyer, R A; Moore, J M; Stern, S A; Weaver, H A; Olkin, C B; Young, L A; Smith, K E

    2016-12-01

    The deep nitrogen-covered basin on Pluto, informally named Sputnik Planitia, is located very close to the longitude of Pluto's tidal axis and may be an impact feature, by analogy with other large basins in the Solar System. Reorientation of Sputnik Planitia arising from tidal and rotational torques can explain the basin's present-day location, but requires the feature to be a positive gravity anomaly, despite its negative topography. Here we argue that if Sputnik Planitia did indeed form as a result of an impact and if Pluto possesses a subsurface ocean, the required positive gravity anomaly would naturally result because of shell thinning and ocean uplift, followed by later modest nitrogen deposition. Without a subsurface ocean, a positive gravity anomaly requires an implausibly thick nitrogen layer (exceeding 40 kilometres). To prolong the lifetime of such a subsurface ocean to the present day and to maintain ocean uplift, a rigid, conductive water-ice shell is required. Because nitrogen deposition is latitude-dependent, nitrogen loading and reorientation may have exhibited complex feedbacks.

  10. Reorientation of Sputnik Planitia implies a subsurface ocean on Pluto

    NASA Astrophysics Data System (ADS)

    Nimmo, F.; Hamilton, D. P.; McKinnon, W. B.; Schenk, P. M.; Binzel, R. P.; Bierson, C. J.; Beyer, R. A.; Moore, J. M.; Stern, S. A.; Weaver, H. A.; Olkin, C. B.; Young, L. A.; Smith, K. E.; Moore, J. M.; McKinnon, W. B.; Spencer, J. R.; Beyer, R.; Binzel, R. P.; Buie, M.; Buratti, B.; Cheng, A.; Cruikshank, D.; Ore, C. Dalle; Earle, A.; Gladstone, R.; Grundy, W.; Howard, A. D.; Lauer, T.; Linscott, I.; Nimmo, F.; Parker, J.; Porter, S.; Reitsema, H.; Reuter, D.; Roberts, J. H.; Robbins, S.; Schenk, P. M.; Showalter, M.; Singer, K.; Strobel, D.; Summers, M.; Tyler, L.; White, O. L.; Umurhan, O. M.; Banks, M.; Barnouin, O.; Bray, V.; Carcich, B.; Chaikin, A.; Chavez, C.; Conrad, C.; Hamilton, D. P.; Howett, C.; Hofgartner, J.; Kammer, J.; Lisse, C.; Marcotte, A.; Parker, A.; Retherford, K.; Saina, M.; Runyon, K.; Schindhelm, E.; Stansberry, J.; Steffl, A.; Stryk, T.; Throop, H.; Tsang, C.; Verbiscer, A.; Winters, H.; Zangari, A.; Stern, S. A.; Weaver, H. A.; Olkin, C. B.; Young, L. A.; Smith, K. E.

    2016-12-01

    The deep nitrogen-covered basin on Pluto, informally named Sputnik Planitia, is located very close to the longitude of Pluto’s tidal axis and may be an impact feature, by analogy with other large basins in the Solar System. Reorientation of Sputnik Planitia arising from tidal and rotational torques can explain the basin’s present-day location, but requires the feature to be a positive gravity anomaly, despite its negative topography. Here we argue that if Sputnik Planitia did indeed form as a result of an impact and if Pluto possesses a subsurface ocean, the required positive gravity anomaly would naturally result because of shell thinning and ocean uplift, followed by later modest nitrogen deposition. Without a subsurface ocean, a positive gravity anomaly requires an implausibly thick nitrogen layer (exceeding 40 kilometres). To prolong the lifetime of such a subsurface ocean to the present day and to maintain ocean uplift, a rigid, conductive water-ice shell is required. Because nitrogen deposition is latitude-dependent, nitrogen loading and reorientation may have exhibited complex feedbacks.

  11. Transient increase in the levels of gamma-tubulin complex in reorientation of cortical microtubules by gravity in azuki bean epicotyls

    NASA Astrophysics Data System (ADS)

    Soga, Kouichi; Kotake, Toshihisa; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    Azuki bean (Vigna angularis Ohwi et Ohashi) seedlings were exposed to centrifugal hypergravity, and the changes in the orientation of cortical microtubules and the expression of genes cording γ-tubulin complex (VaTUBG and VaSpc98p) were examined. By 300 g treatment, the percentage of cells with transverse microtubules was decreased, while that with longitudinal microtubules was increased in epicotyls. Hypergravity increased the expression of VaTUBG and VaSpc98p transiently. Also, the expression of both genes was increased transiently by removal of hypergravity stimulus. Lanthanum and gadolinium ions, potential blockers of mechanosensitive calcium ion-permeable channels (mechanoreceptors), nullified reorientation of microtubules as well as up-regulation of expression of VaTUBG and VaSpc98p by hypergravity. These results suggest that mechanoreceptors on the plasma membrane may perceive the gravity signal, which leads to reorientation of cortical microtubules by transiently stimulating the formation of γ-tubulin complex.

  12. A theoretical investigation of soliton induced supercontinuum generation in liquid core photonic crystal fiber and dual core optical fiber

    NASA Astrophysics Data System (ADS)

    Porsezian, K.; Nithyanandan, K.; Vasantha Jayakantha Raja, R.; Ganapathy, R.

    2013-07-01

    The supercontinuum generation (SCG) in liquid core photonic crystal fiber (LCPCF) with versatile nonlinear response and the spectral broadening in dual core optical fiber is presented. The analysis is presented in two phase, phase I deals with the SCG in LCPCF with the effect of saturable nonlinearity and re-orientational nonlinearity. We identify and discuss the generic nature of the saturable nonlinearity and reorientational nonlinearity in the SCG, using suitable model. For the physical explanation, modulational instability and soliton fission techniques is implemented to investigate the impact of saturable nonlinear response and slow nonlinear response, respectively. It is observed that the saturable nonlinearity inevitably suppresses the MI and the subsequent SCG. On the other hand, the re-orientational nonlinearity contributes to the slow nonlinear response in addition to the conventional fast response due to the electronic contribution. The phase II features the exclusive investigation of the spectral broadening in the dual core optical fiber.

  13. Features of Relaxation of a Stress Tensor in the Microscopic Volume of Nematic Phase under the Action of a Strong Electric Field

    NASA Astrophysics Data System (ADS)

    Zakharov, A. V.

    2018-02-01

    A numerical study of new regimes of reorientation of director field n̂, velocity v, and components of stress tensor σ ij ( ij = x, y, z) of nematic liquid crystal (LC) encapsulated in a rectangular channel under the action of a strong electric field E directed at angle α ( {˜{π }/{2}} ) to the horizontal surfaces bounding the LC channel is proposed. The numerical calculations performed in the framework of nonlinear generalization of the classical Eriksen-Leslie theory have shown that at certain relations between the torques and momenta affecting the unit LC volume and E ≫ E th, transition periodic structures can emerge during reorientation of n̂, if the corresponding distortion mode has the fastest response, and, thus, suppress all other modes. Rotating domains originating within this process decrease the energy dissipation rate and create more favorable regimes of the director field reorientation, as compared with the uniform rotational displacement.

  14. Intragranular twinning, detwinning, and twinning-like lattice reorientation in magnesium alloys

    DOE PAGES

    Wu, Wei; Gao, Yanfei; Oak Ridge National Lab.; ...

    2016-09-11

    We present that deformation twinning plays a critical role on improving metals or alloys ductility, especially for hexagonal close-packed materials with low symmetry crystal structure. A rolled Mg alloy was selected as a model system to investigate the extension twinning behaviors and characteristics of parent-twin interactions by nondestructive in situ 3D synchrotron X-ray microbeam diffraction. Besides twinning- detwinning process, the twinning-like lattice reorientation process was captured within an individual grain inside a bulk material during the strain reversal. The distributions of parent, twin, and reorientated grains and sub-micron level strain variation across the twin boundary are revealed. A theoretical calculationmore » of the lattice strain confirms that the internal strain distribution in parent and twinned grains correlates with the experimental setup, grain orientation of parent, twin, and surrounding grains, as well as the strain path changes. In conclusion, the study suggests a novel deformation mechanism within the hexagonal close-packed structure that cannot be determined from surface-based characterization methods.« less

  15. Spin-reorientation transitions in the Cairo pentagonal magnet Bi 4 Fe 5 O 13 F

    DOE PAGES

    Tsirlin, Alexander A.; Rousochatzakis, Ioannis; Filimonov, Dmitry; ...

    2017-09-19

    Here, we show that interlayer spins play a dual role in the Cairo pentagonal magnet Bi 4Fe 5O 13F, on one hand mediating the three-dimensional magnetic order, and on the other driving spin-reorientation transitions both within and between the planes. The corresponding sequence of magnetic orders unraveled by neutron diffraction and Mössbauer spectroscopy features two orthogonal magnetic structures described by opposite local vector chiralities, and an intermediate, partly disordered phase with nearly collinear spins. A similar collinear phase has been predicted theoretically to be stabilized by quantum fluctuations, but Bi 4Fe 5O 13F is very far from the relevant parametermore » regime. While the observed in-plane reorientation cannot be explained by any standard frustration mechanism, our ab initio band-structure calculations reveal strong single-ion anisotropy of the interlayer Fe 3+ spins that turns out to be instrumental in controlling the local vector chirality and the associated interlayer order.« less

  16. Spin-reorientation transitions in the Cairo pentagonal magnet Bi4Fe5O13F

    NASA Astrophysics Data System (ADS)

    Tsirlin, Alexander A.; Rousochatzakis, Ioannis; Filimonov, Dmitry; Batuk, Dmitry; Frontzek, Matthias; Abakumov, Artem M.

    2017-09-01

    We show that interlayer spins play a dual role in the Cairo pentagonal magnet Bi4Fe5O13F , on one hand mediating the three-dimensional magnetic order, and on the other driving spin-reorientation transitions both within and between the planes. The corresponding sequence of magnetic orders unraveled by neutron diffraction and Mössbauer spectroscopy features two orthogonal magnetic structures described by opposite local vector chiralities, and an intermediate, partly disordered phase with nearly collinear spins. A similar collinear phase has been predicted theoretically to be stabilized by quantum fluctuations, but Bi4Fe5O13F is very far from the relevant parameter regime. While the observed in-plane reorientation cannot be explained by any standard frustration mechanism, our ab initio band-structure calculations reveal strong single-ion anisotropy of the interlayer Fe3 + spins that turns out to be instrumental in controlling the local vector chirality and the associated interlayer order.

  17. Spontaneous reorientations of meta-atoms and electromagnetic spatial solitons in a liquid metacrystal.

    PubMed

    Zharov, Alexander A; Zharov, Alexander A; Zharova, Nina A

    2014-08-01

    We show that transverse electromagnetic waves propagating along an external static electric field in liquid metacrystal (LMC) can provoke spontaneous rearrangement of elongated meta-atoms that changes the direction of the anisotropy axis of the LMC. This kind of instability may reorient the meta-atoms from the equilibrium state parallel to a static field to the state along a high-frequency field and back at the different threshold intensities of electromagnetic waves in such a way that bistability in the system takes place. Reorientation of meta-atoms causes a change in the effective refraction index of LMC that creates, in turn, the conditions for the formation of bright spatial solitons. Such spatial solitons are the self-consistent domains of redirected meta-atoms with trapped photons. We find that the instability thresholds as well as energy flux captured by the spatial soliton can be easily managed by variation of the static electric field applied to the LMC. We study the effects of soliton excitation and collisions via numerical simulations.

  18. Influence of hydride orientation on fracture toughness of CWSR Zr-2.5%Nb pressure tube material between RT and 300 °C

    NASA Astrophysics Data System (ADS)

    Sharma, Rishi K.; Sunil, Saurav; Kumawat, B. K.; Singh, R. N.; Tewari, Asim; Kashyap, B. P.

    2017-05-01

    An experimental setup was designed, fabricated and used to form radial hydrides in Zr-2.5%Nb alloy pressure tube spool. The design of setup was based on ensuring a hoop stress in the spool greater than threshold stress for reorientation of hydrides in this alloy, which was achieved by manipulating the thermal expansion coefficient of the plunger and pressure tube material and diametral interference between them. The experimental setup was loaded on a universal testing machine (UTM) fitted with an environmental chamber and subjected to a temperature cycle for the stress reorientation treatment. The metallographic examination of the hydrogen charged spools subjected to stress re-orientation treatment using this set up revealed formation of predominantly radial hydrides. The variation of fracture toughness of material containing radial hydride with test temperature showed typical 'S' curve behavior with transition temperatures more than that of the material containing circumferential hydride.

  19. Look up: Human adults use vertical height cues in reorientation.

    PubMed

    Du, Yu; Spetch, Marcia L; Mou, Weimin

    2016-11-01

    Numerous studies have shown that people and other animals readily use horizontal geometry (distance and directional information) to reorient, and these cues sometimes dominate over other cues when reorienting in navigable environments. Our study investigated whether horizontal cues (distance/angle) dominate over vertical cues (wall height) when they are in conflict. Adult participants learned two locations (opposite corners) in either a rectangular room (with distance information) or a rhombus room (with angle information). Both training rooms had 2 opposite high walls as height cues. On each trial, participants were disoriented and then asked to locate the correct corners. In testing, the rooms were modified to provide (a) distance or angle cues only, (b) height cues only, and (c) both height and horizontal cues in conflict. Participants located the correct corners successfully with horizontal (distance/angle) or height cues alone. On conflict tests, participants did not show preference for the horizontal information (distance/angle) over the height cues. The results are discussed in terms of the geometric module theory and the adaptive combination theory.

  20. SPHERES HALO

    NASA Image and Video Library

    2017-06-23

    iss052e006482 (6/23/2017) --- Astronaut Peggy Whitson is photographed during a test session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) Halo investigation in the Kibo module. The SPHERES Halo investigation studies the possibility of launching several separate components and then attaching them once they are in space. The investigation upgrades the International Space Station’s fleet of SPHERES to enable each SPHERE to communicate with six external objects at the same time, testing new control and remote assembly methods.

  1. Polymorphic phase transitions and molecular motion in pyridinium chlorochromate

    NASA Astrophysics Data System (ADS)

    Pajaķ, Z.; Szafrańska, B.; Czarnecki, P.; Mayer, J.; Kozak, A.

    1997-08-01

    DTA, DSC, NMR and dielectric studies have been performed for pyridinium chlorochromate over a wide temperature range. A sequence of four solid-solid phase transitions was discovered. The in-plane complex reorientation of the cation is described by a three-well potential model with two correlation times. At higher temperatures one observes simultaneous cation tumbling and diffusion. Thus existence of a new ionic plastic phase is revealed. The domain structure observed suggests ferroelastic properties of the compound.

  2. SPHERES Zero Robotics Session

    NASA Image and Video Library

    2013-05-23

    ISS036-E-003308(23 May 2013) --- Onboard the International Space Station, Expedition 36 Flight Engineer Chris Cassidy, NASA astronaut, watches from just out of frame as he devotes some time with the long-running SPHERES experiment, also known as Synchronized Position Hold Engage and Reorient Experimental Satellites. The experiment is run in conjunction with students who program bowling ball-sized satellites using algorithms. The free-floating satellites are programmed to perform maneuvers potentially influencing the design of future missions.

  3. Reorientation and faulting of Pluto due to volatile loading within Sputnik Planitia.

    PubMed

    Keane, James T; Matsuyama, Isamu; Kamata, Shunichi; Steckloff, Jordan K

    2016-12-01

    Pluto is an astoundingly diverse, geologically dynamic world. The dominant feature is Sputnik Planitia-a tear-drop-shaped topographic depression approximately 1,000 kilometres in diameter possibly representing an ancient impact basin. The interior of Sputnik Planitia is characterized by a smooth, craterless plain three to four kilometres beneath the surrounding rugged uplands, and represents the surface of a massive unit of actively convecting volatile ices (N 2 , CH 4 and CO) several kilometres thick. This large feature is very near the Pluto-Charon tidal axis. Here we report that the location of Sputnik Planitia is the natural consequence of the sequestration of volatile ices within the basin and the resulting reorientation (true polar wander) of Pluto. Loading of volatile ices within a basin the size of Sputnik Planitia can substantially alter Pluto's inertia tensor, resulting in a reorientation of the dwarf planet of around 60 degrees with respect to the rotational and tidal axes. The combination of this reorientation, loading and global expansion due to the freezing of a possible subsurface ocean generates stresses within the planet's lithosphere, resulting in a global network of extensional faults that closely replicate the observed fault networks on Pluto. Sputnik Planitia probably formed northwest of its present location, and was loaded with volatiles over million-year timescales as a result of volatile transport cycles on Pluto. Pluto's past, present and future orientation is controlled by feedbacks between volatile sublimation and condensation, changing insolation conditions and Pluto's interior structure.

  4. Reorientation and faulting of Pluto due to volatile loading within Sputnik Planitia

    NASA Astrophysics Data System (ADS)

    Keane, James T.; Matsuyama, Isamu; Kamata, Shunichi; Steckloff, Jordan K.

    2016-12-01

    Pluto is an astoundingly diverse, geologically dynamic world. The dominant feature is Sputnik Planitia—a tear-drop-shaped topographic depression approximately 1,000 kilometres in diameter possibly representing an ancient impact basin. The interior of Sputnik Planitia is characterized by a smooth, craterless plain three to four kilometres beneath the surrounding rugged uplands, and represents the surface of a massive unit of actively convecting volatile ices (N2, CH4 and CO) several kilometres thick. This large feature is very near the Pluto-Charon tidal axis. Here we report that the location of Sputnik Planitia is the natural consequence of the sequestration of volatile ices within the basin and the resulting reorientation (true polar wander) of Pluto. Loading of volatile ices within a basin the size of Sputnik Planitia can substantially alter Pluto’s inertia tensor, resulting in a reorientation of the dwarf planet of around 60 degrees with respect to the rotational and tidal axes. The combination of this reorientation, loading and global expansion due to the freezing of a possible subsurface ocean generates stresses within the planet’s lithosphere, resulting in a global network of extensional faults that closely replicate the observed fault networks on Pluto. Sputnik Planitia probably formed northwest of its present location, and was loaded with volatiles over million-year timescales as a result of volatile transport cycles on Pluto. Pluto’s past, present and future orientation is controlled by feedbacks between volatile sublimation and condensation, changing insolation conditions and Pluto’s interior structure.

  5. Dynamics of glass-forming di-n-butyl phthalate as studied by NMR.

    PubMed

    Szcześniak, E; Głowinkowski, S; Suchański, W; Jurga, S

    1997-04-01

    Spin-lattice relaxation times T1 and nuclear Overhauser effect (NOE) enhancement factors for the individual ring carbons in di-n-butyl phthalate (DBF) show that the reorientational correlation function corresponding to the global dynamics in supercooled liquid can be described by a Davidson-Cole distribution. Measurements of proton spin-lattice relaxation times T1 and T1p, as well as 1H NMR spectra at temperatures below the glass transition temperature, Tg, reveal that the same distribution holds also for description of local dynamics in glassy DBF. The activation parameters of the motions detected are derived.

  6. Correlations of low-field NMR and variable-field NMR parameters with osteoarthritis in human articular cartilage under load.

    PubMed

    Rössler, Erik; Mattea, Carlos; Saarakkala, Simo; Lehenkari, Petri; Finnilä, Mikko; Rieppo, Lassi; Karhula, Sakari; Nieminen, Miika T; Stapf, Siegfried

    2017-08-01

    NMR experiments carried out at magnetic fields below 1 T provide new relaxation parameters unavailable with conventional clinical scanners. Contrast of T 1 generally becomes larger towards low fields, as slow molecular reorientation processes dominate relaxation at the corresponding Larmor frequencies. This advantage has to be considered in the context of lower sensitivity and frequently reduced spatial resolution. The layered structure of cartilage is one example where a particularly strong variation of T 1 across the tissue occurs, being affected by degenerative diseases such as osteoarthritis (OA). Furthermore, the presence of 1 H- 14  N cross-relaxation, leading to so-called quadrupolar dips in the 1 H relaxation time dispersion, provide insight into the concentration and mobility of proteoglycans and collagen in cartilage, both being affected by OA. In this study, low-field imaging and variable-field NMR relaxometry were combined for the first time for tissue samples, employing unidirectional load to probe the mechanical properties. 20 human knee cartilage samples were placed in a compression cell, and studied by determining relaxation profiles without and with applied pressure (0.6 MPa) at 50 μm in-plane resolution, and comparing with volume-averaged T 1 dispersion. Samples were subsequently stored in formalin, prepared for histology and graded according to the Mankin score system. Quadrupolar dips and thickness change under load showed the strongest correlation with Mankin grade. Average T 1 and change of maximum T 1 under load, as well as its position, correlate with thickness and thickness change. Furthermore, T 1 (ω) above 25 mT was found to correlate with thickness change. While volume-averaged T 1 is not a suitable indicator for OA, its change due to mechanical load and its extreme values are suggested as biomarkers available in low-field MRI systems. The shape of the dispersion T 1 (ω) represents a promising access to understanding and quantifying molecular dynamics in tissue, pointing toward future in vivo tissue studies. Copyright © 2017 John Wiley & Sons, Ltd.

  7. Phase polymorphism of novel [Ru(NH{sub 3}){sub 6}](ClO{sub 4}){sub 3}—Comparison with [Ru(NH{sub 3}){sub 6}](BF{sub 4}){sub 3}. Part II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dołęga, Diana, E-mail: dolega@chemia.uj.edu.pl; Mikuli, Edward, E-mail: mikuli@chemia.uj.edu.pl; Górska, Natalia, E-mail: natalia.gorska@uj.edu.pl

    2013-08-15

    [Ru(NH{sub 3}){sub 6}](ClO{sub 4}){sub 3} undergoes two phase transitions at: T{sub C1}=290.3 K and T{sub C2}=74.8 K , thus exhibits three crystalline phases in the temperature range of 5–310 K. For the detected phase transitions, thermal effects were determined. Fourier transform far- and middle-infrared spectra (FT-FIR and FT-MIR), recorded at 8–350 K, suggest that reorientational motions of the NH{sub 3} ligands are very fast (τ{sub R}≈10{sup −12} s above T{sub C1}) and are significantly slowed down below T{sub C2}. X-ray single crystal diffraction (XRSCD) measurements revealed that in the high temperature phase (above T{sub C1}) the compound belongs to themore » cubic Fm3{sup ¯}m (No. 225) space group, whereas in the intermediate phase the unit cell parameter doubles and the space group is Ia3{sup ¯}(No. 206). {sup 1}H NMR studies revealed that the following reorientational motions are liberated during heating: three-fold reorientation of NH{sub 3} ligands, three-fold reorientation of the entire [Ru(NH{sub 3}){sub 6}]{sup 3+} cation, and isotropic reorientation of this cation. In the high temperature phase I the cations perform isotropic reorientations with the estimated activation energy equal to ca. 30.1 kJ mol{sup −1}. Comparison with adequate results obtained earlier for [Ru(NH{sub 3}){sub 6}](BF{sub 4}){sub 3} and for other similar compounds was made and general regularities were drawn. - Graphical abstract: Molar heat capacities obtained for [Ru(NH{sub 3}){sub 6}](ClO{sub 4}){sub 3} at temperatures between 5 and 310 K. Molecular structure of [Ru(NH{sub 3}){sub 6}]{sup 3+} and two types of ClO{sub 4}{sup -} varying in dynamic disorder at 293 K. Highlights: • Two solid phase transitions have been found in [Ru(NH{sub 3}){sub 6}](ClO{sub 4}){sub 3}. • The transitions are triggered by the hydrogen bond interactions between NH{sub 3} ligands and ClO{sub 4}{sup −} anions. • The complex is a highly dynamically disordered crystal across a wide temperature range.« less

  8. Large isosymmetric reorientation of oxygen octahedra rotation axes in epitaxially strained perovskites.

    PubMed

    Rondinelli, James M; Coh, Sinisa

    2011-06-10

    Using first-principles density functional theory calculations, we discover an anomalously large biaxial strain-induced octahedral rotation axis reorientation in orthorhombic perovskites with tendency towards rhombohedral symmetry. The transition between crystallographically equivalent (isosymmetric) structures with different octahedral rotation magnitudes originates from strong strain-octahedral rotation coupling available to perovskites and the energetic hierarchy among competing octahedral tilt patterns. By elucidating these criteria, we suggest many functional perovskites would exhibit the transition in thin film form, thus offering a new landscape in which to tailor highly anisotropic electronic responses.

  9. Developments and Validations of Fully Coupled CFD and Practical Vortex Transport Method for High-Fidelity Wake Modeling in Fixed and Rotary Wing Applications

    NASA Technical Reports Server (NTRS)

    Anusonti-Inthra, Phuriwat

    2010-01-01

    A novel Computational Fluid Dynamics (CFD) coupling framework using a conventional Reynolds-Averaged Navier-Stokes (BANS) solver to resolve the near-body flow field and a Particle-based Vorticity Transport Method (PVTM) to predict the evolution of the far field wake is developed, refined, and evaluated for fixed and rotary wing cases. For the rotary wing case, the RANS/PVTM modules are loosely coupled to a Computational Structural Dynamics (CSD) module that provides blade motion and vehicle trim information. The PVTM module is refined by the addition of vortex diffusion, stretching, and reorientation models as well as an efficient memory model. Results from the coupled framework are compared with several experimental data sets (a fixed-wing wind tunnel test and a rotary-wing hover test).

  10. Active suppression after involuntary capture of attention.

    PubMed

    Sawaki, Risa; Luck, Steven J

    2013-04-01

    After attention has been involuntarily captured by a distractor, how is it reoriented toward a target? One possibility is that attention to the distractor passively fades over time, allowing the target to become attended. Another possibility is that the captured location is actively suppressed so that attention can be directed toward the target location. The present study investigated this issue with event-related potentials (ERPs), focusing on the N2pc component (a neural measure of attentional deployment) and the Pd component (a neural measure of attentional suppression). Observers identified a color-defined target in a search array, which was preceded by a task-irrelevant cue array. When the cue array contained an item that matched the target color, this item captured attention (as measured both behaviorally and with the N2pc component). This capture of attention was followed by active suppression (indexed by the Pd component), and this was then followed by a reorienting of attention toward the target in the search array (indexed by the N2pc component). These findings indicate that the involuntary capture of attention by a distractor is followed by an active suppression process that presumably facilitates the subsequent voluntary orienting of attention to the target.

  11. Impact evaluation of a health promotion-focused organisational development strategy on a health service's capacity to deliver comprehensive primary health care.

    PubMed

    Costello, Michelle; Taylor, Jane; O'Hara, Lily

    2015-01-01

    A comprehensive primary health care approach is required to address complex health issues and reduce inequities. However, there has been limited uptake of this approach by health services nationally or internationally. Reorienting health services towards becoming more health promoting provides a mechanism to support the delivery of comprehensive primary health care. The aim of this study was to determine the impact of a health promotion-focused organisational development strategy on the capacity of a primary health care service to deliver comprehensive primary health care. A questionnaire and semistructured individual interviews were used to collect quantitative and qualitative impact evaluation data, respectively, from 13 health service staff across three time points with regard to 37 indicators of organisational capacity. There were significant increases in mean scores for 31 indicators, with effect sizes ranging from moderate to nearly perfect. A range of key enablers and barriers to support the delivery of comprehensive primary health care was identified. In conclusion, an organisational development strategy to reorient health services towards becoming more health promoting may increase the capacity to deliver comprehensive primary health care.

  12. Mode-coupling theoretical analysis of transport and relaxation properties of liquid dimethylimidazolium chloride

    NASA Astrophysics Data System (ADS)

    Yamaguchi, T.; Koda, S.

    2010-03-01

    The mode-coupling theory for molecular liquids based on the interaction-site model is applied to a representative molecular ionic liquid, dimethylimidazolium chloride, and dynamic properties such as shear viscosity, self-diffusion coefficients, reorientational relaxation time, electric conductivity, and dielectric relaxation spectrum are analyzed. Molecular dynamics (MD) simulation is also performed on the same system for comparison. The theory captures the characteristics of the dynamics of the ionic liquid qualitatively, although theoretical relaxation times are several times larger than those from the MD simulation. Large relaxations are found in the 100 MHz region in the dispersion of the shear viscosity and the dielectric relaxation, in harmony with various experiments. The relaxations of the self-diffusion coefficients are also found in the same frequency region. The dielectric relaxation spectrum is divided into the contributions of the translational and reorientational modes, and it is demonstrated that the relaxation in the 100 MHz region mainly stems from the translational modes. The zero-frequency electric conductivity is close to the value predicted by the Nernst-Einstein equation in both MD simulation and theoretical calculation. However, the frequency dependence of the electric conductivity is different from those of self-diffusion coefficients in that the former is smaller than the latter in the gigahertz-terahertz region, which is compensated by the smaller dispersion of the former in the 100 MHz region. The analysis of the theoretical calculation shows that the difference in their frequency dependence is due to the different contribution of the short- and long-range liquid structures.

  13. Hydration-Dependent Dynamical Modes in Xyloglucan from Molecular Dynamics Simulation of 13C NMR Relaxation Times and Their Distributions.

    PubMed

    Chen, Pan; Terenzi, Camilla; Furó, István; Berglund, Lars A; Wohlert, Jakob

    2018-05-15

    Macromolecular dynamics in biological systems, which play a crucial role for biomolecular function and activity at ambient temperature, depend strongly on moisture content. Yet, a generally accepted quantitative model of hydration-dependent phenomena based on local relaxation and diffusive dynamics of both polymer and its adsorbed water is still missing. In this work, atomistic-scale spatial distributions of motional modes are calculated using molecular dynamics simulations of hydrated xyloglucan (XG). These are shown to reproduce experimental hydration-dependent 13 C NMR longitudinal relaxation times ( T 1 ) at room temperature, and relevant features of their broad distributions, which are indicative of locally heterogeneous polymer reorientational dynamics. At low hydration, the self-diffusion behavior of water shows that water molecules are confined to particular locations in the randomly aggregated XG network while the average polymer segmental mobility remains low. Upon increasing water content, the hydration network becomes mobile and fully accessible for individual water molecules, and the motion of hydrated XG segments becomes faster. Yet, the polymer network retains a heterogeneous gel-like structure even at the highest level of hydration. We show that the observed distribution of relaxations times arises from the spatial heterogeneity of chain mobility that in turn is a result of heterogeneous distribution of water-chain and chain-chain interactions. Our findings contribute to the picture of hydration-dependent dynamics in other macromolecules such as proteins, DNA, and synthetic polymers, and hold important implications for the mechanical properties of polysaccharide matrixes in plants and plant-based materials.

  14. [Theories on the mode of action of desensitization].

    PubMed

    Klimek, L; Reske-Kunz, A B; Saloga, J

    1999-01-01

    Specific immunotherapy (SIT) has been practised successfully for about 80 years. In classic immunotherapy, an allergen-extract is repeatedly injected subcutaneously in increasing doses. A large number of clinically controlled studies have proved the efficacy of this kind of immunotherapy, while its mode of action is not precisely known yet. A successful SIT leads to an impairment of allergic symptoms (symptom score), and a concordant decrease in drug use. Furthermore, a reduced reactivity in specific dermal, nasal and bronchial provocation tests is induced as well as a diminished unspecific reagibility in the affected tissues. Several studies showed reduced values for allergen-specific IgE (serum) that followed an initial increase. A reduced immigration of eosinophils was found, both after provocation with allergen and during the pollen season, as well as diminished values of markers for the activity of eosinophils, e.g. eosinophil cationic protein (ECP). Also, a reduced allergen-induced histamine-liberation from mast cells and basophils has been reported. The underlying mechanism for these effects of SIT might be a reorientation of the allergen-induced lymphokine-production to a dominant TH1-cytokine-profile. Because the relation between the quantity of IL-4 and its regulator IFN-gamma controls the extent of IgE-synthesis by B-cells, the reorientation leads to a diminished production of IgE. IFN-gamma inhibits the differentiation of TH2-cells; by this less TH2-cells are present to help B-cells to produce IgE-antibodies, and to induce the differentiation of mast cells and basophils as well as immigration, differentiation and activation of eosinophils. Thus, the positive effects of SIT can be explained by the reorientation T-cell lymphokine profile. The mechanism under discussion for explaining this reorientation include: 1) an increased differentiation of allergen-specific CD4+ precursor-cells or a reorientation of established TH2-cells to the production of IFN-gamma, 2) the differentiation of IFN-gamma-producing CD8+ T-cells and of T-cells with receptors for T-cell-antigenes of the gamma, delta-type; and 3) the induction of an energy in TH2-cells.

  15. Bed structure and bedload transport: Sediment grain reorientation in response to high and low flows in an experimental flume

    NASA Astrophysics Data System (ADS)

    Gurer, M.; Sullivan, S.; Masteller, C.

    2016-12-01

    Bedload is a regime of sediment transport that occurs when particles roll, hop, or bounce downstream. This mode of transport represents an important portion of the sediment load in a gravel river. Despite numerous studies focused on bedload transport, it still remains difficult to predict accurately due to the complex arrangement of riverbed particles. The formation of gravel clusters, stones being imbricated, or streamlined, and other interlocked arrangements, as well as grains armoring the bed, all tend to stabilize gravel channels and decrease bed mobility. Typically, the development of bed structure usually occurs as sediment moves downstream. However, it is unclear that gravel bed structure can be developed during weaker flows that do not generate significant sediment transport. We examine how individual sediment grains reorient themselves during low flow conditions, in the absence of sediment transport, and during high flow conditions, as bedload transport occurs. We then perform flume experiments where we expose a gravel bed to varying durations of low flow and raise the water level, simulating a flood and transporting sediment. We also compare the long-axis orientations of grains before and after each low flow period and transport. We find that sediment grains reorient themselves differently during low and high flows. During low flow, grains appear to reorient themselves with the long-axes towards cross-stream direction, or perpendicular to the flow, with longer duration flows resulting in more pronounced cross-stream orientation. During high flow, grains orient themselves with their long-axes facing downstream or parallel to the flow, similar to imbricated grains observed in the sedimentary record. Further, when transport occurs, we find that median grain orientation is strongly correlated with bedload transport rates (R^2 = 0.98). We also observe that median grain orientations more perpendicular to downstream flow result in reduced transport rates. This new result suggests that the low flow reorientation of grains perpendicular to downstream flow drives observed differences in bedload transport during high flows. We conclude that low flow periods are important for the creation of bed structure and the stabilization of gravel river channels.

  16. Zero-Field Spin Structure and Spin Reorientations in Layered Organic Antiferromagnet, κ-(BEDT-TTF)2Cu[N(CN)2]Cl, with Dzyaloshinskii-Moriya Interaction

    NASA Astrophysics Data System (ADS)

    Ishikawa, Rui; Tsunakawa, Hitoshi; Oinuma, Kohsuke; Michimura, Shinji; Taniguchi, Hiromi; Satoh, Kazuhiko; Ishii, Yasuyuki; Okamoto, Hiroyuki

    2018-06-01

    Detailed magnetization measurements enabled us to claim that the layered organic insulator κ-(BEDT-TTF)2Cu[N(CN)2]Cl [BEDT-TTF: bis(ethylenedithio)tetrathiafulvalene] with the Dzyaloshinskii-Moriya interaction has an antiferromagnetic spin structure with the easy axis being the crystallographic c-axis and the net canting moment parallel to the a-axis at zero magnetic field. This zero-field spin structure is significantly different from that proposed in the past studies. The assignment was achieved by arguments including a correction of the direction of the weak ferromagnetism, reinterpretations of magnetization behaviors, and reasoning based on known high-field spin structures. We suggest that only the contributions of the strong intralayer antiferromagnetic interaction, the moderately weak Dzyaloshinskii-Moriya interaction, and the very weak interlayer ferromagnetic interaction can realize this spin structure. On the basis of this model, characteristic magnetic-field dependences of the magnetization can be interpreted as consequences of intriguing spin reorientations. The first reorientation is an unusual spin-flop transition under a magnetic field parallel to the b-axis. Although the existence of this transition is already known, the interpretation of what happens at this transition has been significantly revised. We suggest that this transition can be regarded as a spin-flop phenomenon of the local canting moment. We also claim that half of the spins rotate by 180° at this transition, in contrast to the conventional spin flop transition. The second reorientation is the gradual rotation of the spins during the variation of the magnetic field parallel to the c-axis. In this process, all the spins rotate around the Dzyaloshinskii-Moriya vectors by 90°. The results of our simulation based on the classical spin model well reproduce these spin reorientation behaviors, which strongly support our claimed zero-field spin structure. The present study highlights the intriguing low-field magnetic properties of this material and may evoke further research on the low-field magnetism in this class of materials.

  17. Electrophysiological correlates of stimulus-driven reorienting deficits after interference with right parietal cortex during a spatial attention task: a TMS-EEG study

    PubMed Central

    Capotosto, Paolo; Corbetta, Maurizio; Romani, Gian Luca; Babiloni, Claudio

    2013-01-01

    Transcranial magnetic stimulation (TMS) interference over right intraparietal sulcus (IPS) causally disrupts behaviorally and electroencephalographic (EEG) rhythmic correlates of endogenous spatial orienting prior to visual target presentation (Capotosto et al. 2009; 2011). Here we combine data from our previous studies to examine whether right parietal TMS during spatial orienting also impairs stimulus-driven re-orienting or the ability to efficiently process unattended stimuli, i.e. stimuli outside the current focus of attention. Healthy subjects (N=24) performed a Posner spatial cueing task while their EEG activity was being monitored. Repetitive TMS (rTMS) was applied for 150 milliseconds (ms) simultaneously to the presentation of a central arrow directing spatial attention to the location of an upcoming visual target. Right IPS-rTMS impaired target detection, especially for stimuli presented at unattended locations; it also caused a modulation of the amplitude of parieto-occipital positive ERPs peaking at about 480 ms (P3) post-target. The P3 significantly decreased for unattended targets, and significantly increased for attended targets after right IPS-rTMS as compared to Sham stimulation. Similar effects were obtained for left IPS stimulation albeit in a smaller group of subjects. We conclude that disruption of anticipatory processes in right IPS has prolonged effects that persist during target processing. The P3 decrement may reflect interference with post-decision processes that are part of stimulus-driven re-orienting. Right IPS is a node of functional interaction between endogenous spatial orienting and stimulus-driven re-orienting processes in human vision. PMID:22905824

  18. Molecular dynamics simulations on PGLa using NMR orientational constraints.

    PubMed

    Sternberg, Ulrich; Witter, Raiker

    2015-11-01

    NMR data obtained by solid state NMR from anisotropic samples are used as orientational constraints in molecular dynamics simulations for determining the structure and dynamics of the PGLa peptide within a membrane environment. For the simulation the recently developed molecular dynamics with orientational constraints technique (MDOC) is used. This method introduces orientation dependent pseudo-forces into the COSMOS-NMR force field. Acting during a molecular dynamics simulation these forces drive molecular rotations, re-orientations and folding in such a way that the motional time-averages of the tensorial NMR properties are consistent with the experimentally measured NMR parameters. This MDOC strategy does not depend on the initial choice of atomic coordinates, and is in principle suitable for any flexible and mobile kind of molecule; and it is of course possible to account for flexible parts of peptides or their side-chains. MDOC has been applied to the antimicrobial peptide PGLa and a related dimer model. With these simulations it was possible to reproduce most NMR parameters within the experimental error bounds. The alignment, conformation and order parameters of the membrane-bound molecule and its dimer were directly derived with MDOC from the NMR data. Furthermore, this new approach yielded for the first time the distribution of segmental orientations with respect to the membrane and the order parameter tensors of the dimer systems. It was demonstrated the deuterium splittings measured at the peptide to lipid ratio of 1/50 are consistent with a membrane spanning orientation of the peptide.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Josefsson, Gabriella; Gamstedt, E. Kristofer; Ahvenainen, Patrik

    The mechanical performance of materials reinforced by cellulose nanofibrils is highly affected by the orientation of these fibrils. This paper investigates the nanofibril orientation distribution of films of partly oriented cellulose nanofibrils. Stripes of hydrogel films were subjected to different amount of strain and, after drying, examined with X-ray diffraction to obtain the orientation of the nanofibrils in the films, caused by the stretching. The cellulose nanofibrils had initially a random in-plane orientation in the hydrogel films and the strain was applied to the films before the nanofibrils bond tightly together, which occurs during drying. The stretching resulted in amore » reorientation of the nanofibrils in the films, with monotonically increasing orientation towards the load direction with increasing strain. Estimation of nanofibril reorientation by X-ray diffraction enables quantitative comparison of the stretch-induced orientation ability of different cellulose nanofibril systems. The reorientation of nanofibrils as a consequence of an applied strain is also predicted by a geometrical model of deformation of nanofibril hydrogels. Conversely, in high-strain cold-drawing of wet cellulose nanofibril materials, the enhanced orientation is promoted by slipping of the effectively stiff fibrils.« less

  20. Single crystal growth, magnetic and thermal properties of perovskite YFe0.6Mn0.4O3 single crystal

    NASA Astrophysics Data System (ADS)

    Xie, Tao; Shen, Hui; Zhao, Xiangyang; Man, Peiwen; Wu, Anhua; Su, Liangbi; Xu, Jiayue

    2016-11-01

    High quality YFe0.6Mn0.4O3 single crystal was grown by floating zone technique using a four-mirror-image-furnace under flowing air. Powder X-ray diffraction gives well evidence that the specimen has an orthorhombic structure, with space group Pbnm. Temperature dependence of the magnetizations of YFe0.6Mn0.4O3 single crystal were studied under ZFC and FC modes in the temperature range from 5 K to 400 K. A clear spin reorientation transition behavior (Γ4→Γ1) is observed in the temperature range of 322-316 K, due to the substitution of Mn at the Fe site of YFeO3. Its Néel temperature is around 385 K. Moreover, the spin reorientation is verified by the change of magnetic hysteresis loops of the sample along [001] axis in the temperature range of 50-385 K. The thermal properties of the sample were measured by the differential scanning calorimeter (DSC) from 300 K to 500 K, which also clearly appear anomaly in the spin reorientation region.

  1. Intragranular twinning, detwinning, and twinning-like lattice reorientation in magnesium alloys

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Wei; Gao, Yanfei; Li, Nan

    2016-12-01

    Deformation twinning plays a critical role on improving metals or alloys ductility, especially for hexagonal close-packed materials with low symmetry crystal structure. A rolled Mg alloy was selected as a model system to investigate the extension twinning behaviors and characteristics of parent-twin interactions by nondestructive in situ 3D synchrotron X-ray microbeam diffraction. Besides twinning-detwinning process, the "twinning-like" lattice reorientation process was captured within an individual grain inside a bulk material during the strain reversal. The distributions of parent, twin, and reorientated grains and sub-micron level strain variation across the twin boundary are revealed. A theoretical calculation of the lattice strainmore » confirms that the internal strain distribution in parent and twinned grains correlates with the experimental setup, grain orientation of parent, twin, and surrounding grains, as well as the strain path changes. The study suggests a novel deformation mechanism within the hexagonal close-packed structure that cannot be determined from surface-based characterization methods. (C) 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.« less

  2. Magnetic spin structure and magnetoelectric coupling in BiFeO{sub 3}-BaTiO{sub 3} multilayer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lazenka, Vera, E-mail: Vera.Lazenka@fys.kuleuven.be; Modarresi, Hiwa; Bisht, Manisha

    2015-02-23

    Magnetic spin structures in epitaxial BiFeO{sub 3} single layer and an epitaxial BaTiO{sub 3}/BiFeO{sub 3} multilayer thin film have been studied by means of nuclear resonant scattering of synchrotron radiation. We demonstrate a spin reorientation in the 15 × [BaTiO{sub 3}/BiFeO{sub 3}] multilayer compared to the single BiFeO{sub 3} thin film. Whereas in the BiFeO{sub 3} film, the net magnetic moment m{sup →} lies in the (1–10) plane, identical to the bulk, m{sup →} in the multilayer points to different polar and azimuthal directions. This spin reorientation indicates that strain and interfaces play a significant role in tuning the magnetic spin order.more » Furthermore, large difference in the magnetic field dependence of the magnetoelectric coefficient observed between the BiFeO{sub 3} single layer and multilayer can be associated with this magnetic spin reorientation.« less

  3. Nd-ordering-driven Mn spin reorientation and magnetization reversal in the magnetostructurally coupled compound NdMn O3

    NASA Astrophysics Data System (ADS)

    Kumar, A.; Yusuf, S. M.; Ritter, C.

    2017-07-01

    A detailed neutron diffraction study on NdMn O3 infers that the low temperature transition at 15 K is due to the ordering of Nd sublattice moment with a (0 ,-Fy,0 ) type spin arrangement. Interestingly, the ordering of the Nd sublattice drives a reorientation (by 180∘) of the net ferromagnetic moment of the Mn sublattice along the b axis. Such a Mn spin reorientation from (Ax,Fy,0 ) (with an antiferromagnetic ordering temperature of 73 K) to (Ax,-Fy,0 ) at 15 K, explains the magnetization reversal phenomenon present in this perovskite compound at 15 K. Moreover at 15 K, significant crystallographic structural distortions in terms of temperature variations of lattice parameters and bond angles are found. A sign change in the temperature variation of magnetic entropy is also found at 15 K. The present study signifies the role of rare-earth (Nd) moment ordering in tuning various physical properties, such as magnetocaloric and magnetoelastic of the larger size (>0.912 Å ) R ion based R Mn O3 compounds.

  4. Otolithic and extraocular muscle proprioceptive influences on the spatial organization of the vestibulo- and cervico-ocular quick phases.

    PubMed

    Pettorossi, V E; Manni, E; Errico, P; Ferraresi, A; Bortolami, R

    1997-03-01

    The cervico-ocular reflex (COR) was studied alone or in combination with the vestibulo-ocular reflex (VOR) in the rabbit. Step stimulations of the body with respect to the fixed head induced small slow compensatory responses followed by large compensatory quick phases (QP). These responses remained aligned with the horizon at different head pitch angles. The QP reorientation in space was due to the gravity influence on the otolithic receptors. The vestibular induced QPs exhibit a similar pattern. Because of this reorientation, the reduction of the amplitude of the vestibular induced QPs, due to the addition of the COR, was maintained even at different static head positions. The electrolytic lesion of the ophthalmic branch of the trigeminal nerve deeply affected the space orientation of the COR. In particular, the cervically induced compensatory QPs of the eye ipsilateral to the lesion showed a remarkable variability of their trajectories and they lost space reorientation. These findings suggest that the coordinate system controlling the QPs is influenced by signals originating from both head position in space and eye position in the orbit.

  5. Electric control of magnetization reorientation in FeRh /BaTiO3 mediated by a magnetic phase transition

    NASA Astrophysics Data System (ADS)

    Odkhuu, Dorj

    2017-10-01

    Employing first-principles calculations we predict magnetization reorientation in FeRh films epitaxially grown on BaTiO3 by reversing the electric polarization or applying the strain effect, which is associated with the recently discovered voltage-induced interfacial magnetic-phase transition by R. O. Cherifi et al. [Nat. Mater. 13, 345 (2014), 10.1038/nmat3870]. We propose that this transition from antiferromagnetic to ferromagnetic phase is the results of the mutual mechanisms of the polarization-reversal-induced volume/strain expansion in the interfacial FeRh layers and the competition between direct and indirect exchange interactions. These mechanisms are mainly driven by the ferroelectrically driven hybridization between Fe and Ti 3 d orbital states at the interface. Such a strong hybridization can further involve Rh 4 d states with large spin-orbit coupling, which, rather than the Fe 3 d orbitals, is responsible for magnetization reorientation at the magnetic-phase transition. These findings point toward the feasibility of electric field control of magnetization switching associated with the magnetic-phase transition in an antiferromagnet structure.

  6. Health promotion and health systems: some unfinished business.

    PubMed

    Ziglio, Erio; Simpson, Sarah; Tsouros, Agis

    2011-12-01

    One of the five action domains in the Ottawa Charter was Reorienting Health Services. In this paper, we reflect on why progress in this domain has been somewhat lethargic, particularly compared with some of the other action domains, and why now it is important to renew our commitment to this domain. Reorienting health services has been largely overlooked and opportunities missed, although good exceptions do exist. The occasion of the 25th anniversary of the Ottawa Charter represents an important opportunity for health promotion to: (i) renew its active voice in current policy debate and action and (ii) enhance achievements made to date by improving our efforts to advocate, enable and mediate for the reorientation of health services and systems. We outline six steps to reactivate and invest more in this action domain so as to be in a better position to promote health equitably and sustainably in today's fast changing world. Though our experience is mainly based in the European context, we hope that our reflections will be of some value to countries outside of this region.

  7. White matter structure in loneliness: preliminary findings from diffusion tensor imaging.

    PubMed

    Tian, Yin; Liang, Shanshan; Yuan, Zhen; Chen, Sifan; Xu, Peng; Yao, Dezhong

    2014-08-06

    A pilot study was carried out to determine individual differences in perceived loneliness using diffusion tensor imaging. To the best of our knowledge, this is the first preliminary diffusion tensor imaging evidence that the ventral attention network, generally activated by attentional reorienting, was also related to loneliness. Image reconstruction results indicated significantly decreased fractional anisotropy of white matter fibers and that associated nodes of the ventral attention network are highly correlated with increased loneliness ratings. By providing evidence on the structural level, our findings suggested that attention-reorienting capabilities play an important role in shaping an individual's loneliness.

  8. Reorienting health systems to meet the demand for consumer health solutions.

    PubMed

    Buckeridge, David L

    2014-01-01

    There is a clear and pronounced gap between the demand for and access to consumer health solutions. Existing health information systems and broader health system factors such as funding models are reasons for this gap. There are strong arguments from the perspectives of the consumer and population health for closing this gap, but the case from the perspective of the current health system is mixed. Closing the gap will require a concerted effort to reorient health information systems and funding models to support online access by consumers to health information and health services.

  9. Slosh wave excitation due to cryogenic liquid reorientation in space-based propulsion system

    NASA Technical Reports Server (NTRS)

    Hung, R. J.; Shyu, K. L.; Lee, C. C.

    1991-01-01

    The objective of the cryogenic fluid management of the spacecraft propulsion system is to develop the technology necessary for acquistion or positioning of liquid and vapor within a tank in reduced gravity to enable liquid outflow or vapor venting. In this study slosh wave excitation induced by the resettling flow field activated by 1.0 Hz medium frequency impulsive reverse gravity acceleration during the course of liquid fluid reorientation with the initiation of geyser for liquid filled levels of 30, 50, and 80 percent have been studied. Characteristics of slosh waves with various frequencies excited are discussed.

  10. The contribution of reorientational nonlinearity of CS2 liquid in supercontinuum generation

    NASA Astrophysics Data System (ADS)

    Porsezian, K.; Raja, R. Vasantha Jayakantha; Husakou, Anton; Hermann, Joachim

    2011-08-01

    We aim to study the nonlinear optical phenomena with femtosecond pulse propagation in liquid-core photonic crystal fibers filled with CS2. In particular, we intend to study the effect of slow nonlinearity due to reorientational contribution of liquid molecules on broadband supercontinuum generation in the femtosecond regime using appropriately modified nonlinear Schrödinger equation. We show that the response of the slow nonlinearity enhances broadening of the pulse and changes the dynamics of the generated solitons. To analyse the quality of the pulse, the stability analysis and coherence of the SCG are studied numerically.

  11. Dynamic Isovector Reorientation of Deuteron as a Probe to Nuclear Symmetry Energy.

    PubMed

    Ou, Li; Xiao, Zhigang; Yi, Han; Wang, Ning; Liu, Min; Tian, Junlong

    2015-11-20

    We present the calculations on a novel reorientation effect of deuteron attributed to isovector interaction in the nuclear field of heavy target nuclei. The correlation angle determined by the relative momentum vector of the proton and the neutron originating from the breakup deuteron, which is experimentally detectable, exhibits significant dependence on the isovector nuclear potential but is robust against the variation of the isoscaler sector. In terms of sensitivity and cleanness, the breakup reactions induced by the polarized deuteron beam at about 100 MeV/u provide a more stringent constraint to the symmetry energy at subsaturation densities.

  12. Theoretical study of electronic transfer current rate at dye-sensitized solar cells

    NASA Astrophysics Data System (ADS)

    AL-Agealy, Hadi J. M.; AlMaadhede, Taif Saad; Hassooni, Mohsin A.; Sadoon, Abbas K.; Ashweik, Ahmed M.; Mahdi, Hind Abdlmajeed; Ghadhban, Rawnaq Qays

    2018-05-01

    In this research, we present a theoretical study of electronic transfer kinetics rate in N719/TiO2 and N719/ZnO dye-sensitized solar cells (DSSC) systems using a simple model depending on the postulate of quantum mechanics theory. The evaluation of the electronic transition current rate in DSSC systems are function of many parameters such that; the reorientation transition energies ΛSe m D y e , the transition coupling parameter ℂT(0), potential exponential effect e-(E/C-EF ) kBT , unit cell volume VSem, and temperature T. Furthermore, the analysis of electronic transfer current rate in N719/TiO2 and N719/ZnO systems show that the rate upon dye-sensitization solar cell increases with increases of transition coupling parameter, decreasing potential that building at interface a results of different material in this devices and increasing with reorientation transition energy. On the other hand, we can find the electronic transfer behavior is dependent of the dye absorption spectrum and mainly depending on the reorientation of transition energy. The replacement of the solvents in both DSSC system caused increasing of current rates dramatically depending on polarity of solvent in subset devices. This change in current rate of electron transfer were attributed to much more available of recombination sites introduced by the solvents medium. The electronic transfer current dynamics are shown to occurs in N719/TiO2 system faster many time compare to ocuures at N719/ZnO system, this indicate that TiO2 a is a good and active material compare with ZnO to using in dye sensitized solar cell devices. In contrast, the large current rate in N719/TiO2 comparing to ZnO of N719/ZnO systems indicate that using TiO2 with N719 dye lead to increasing the efficiency of DSSC.

  13. A high-fat high-sugar diet-induced impairment in place-recognition memory is reversible and training-dependent.

    PubMed

    Tran, Dominic M D; Westbrook, R Frederick

    2017-03-01

    A high-fat high-sugar (HFHS) diet is associated with cognitive deficits in people and produces spatial learning and memory deficits in rodents. Notable, such diets rapidly impair place-, but not object-recognition memory in rats within one week of exposure. Three experiments examined whether this impairment was reversed by removal of the diet, or prevented by pre-diet training. Experiment 1 showed that rats switched from HFHS to chow recovered from the place-recognition impairment that they displayed while on HFHS. Experiment 2 showed that control rats ("Untrained") who were exposed to an empty testing arena while on chow, were impaired in place-recognition when switched to HFHS and tested for the first time. However, rats tested ("Trained") on the place and object task while on chow, were protected from the diet-induce deficit and maintained good place-recognition when switched to HFHS. Experiment 3 examined the conditions of this protection effect by training rats in a square arena while on chow, and testing them in a rectangular arena while on HFHS. We have previously demonstrated that chow rats, but not HFHS rats, show geometry-based reorientation on a rectangular arena place-recognition task (Tran & Westbrook, 2015). Experiment 3 assessed whether rats switched to the HFHS diet after training on the place and object tasks in a square area, would show geometry-based reorientation in a rectangular arena. The protective benefit of training was replicated in the square arena, but both Untrained and Trained HFHS failed to show geometry-based reorientation in the rectangular arena. These findings are discussed in relation to the specificity of the training effect, the role of the hippocampus in diet-induced deficits, and their implications for dietary effects on cognition in people. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Reorientational dynamics in molecular liquids as revealed by dynamic light scattering: from boiling point to glass transition temperature.

    PubMed

    Schmidtke, B; Petzold, N; Kahlau, R; Rössler, E A

    2013-08-28

    We determine the reorientational correlation time τ of a series of molecular liquids by performing depolarized light scattering experiments (double monochromator, Fabry-Perot interferometry, and photon correlation spectroscopy). Correlation times in the range 10(-12) s-100 s are compiled, i.e., the full temperature interval between the boiling point and the glass transition temperature T(g) is covered. We focus on low-T(g) liquids for which the high-temperature limit τ ≅ 10(-12) s is easily accessed by standard spectroscopic equipment (up to 440 K). Regarding the temperature dependence three interpolation formulae of τ(T) with three parameters each are tested: (i) Vogel-Fulcher-Tammann equation, (ii) the approach recently discussed by Mauro et al. [Proc. Natl. Acad. Sci. U.S.A. 106, 19780 (2009)], and (iii) our approach decomposing the activation energy E(T) in a constant high temperature value E∞ and a "cooperative part" E(coop)(T) depending exponentially on temperature [Schmidtke et al., Phys. Rev. E 86, 041507 (2012)]. On the basis of the present data, approaches (i) and (ii) are insufficient as they do not provide the correct crossover to the high-temperature Arrhenius law clearly identified in the experimental data while approach (iii) reproduces the salient features of τ(T). It allows to discuss the temperature dependence of the liquid's dynamics in terms of a E(coop)(T)/E∞ vs. T/E∞ plot and suggests that E∞ controls the energy scale of the glass transition phenomenon.

  15. Direct in situ measurement of coupled magnetostructural evolution in a ferromagnetic shape memory alloy and its theoretical modeling

    DOE PAGES

    Pramanick, Abhijit; Shapiro, Steve M.; Glavic, Artur; ...

    2015-10-14

    In this study, ferromagnetic shape memory alloys (FSMAs) have shown great potential as active components in next generation smart devices due to their exceptionally large magnetic-field-induced strains and fast response times. During application of magnetic fields in FSMAs, as is common in several magnetoelastic smart materials, there occurs simultaneous rotation of magnetic moments and reorientation of twin variants, resolving which, although critical for design of new materials and devices, has been difficult to achieve quantitatively with current characterization methods. At the same time, theoretical modeling of these phenomena also faced limitations due to uncertainties in values of physical properties suchmore » as magnetocrystalline anisotropy energy (MCA), especially for off-stoichiometric FSMA compositions. Here, in situ polarized neutron diffraction is used to measure directly the extents of both magnetic moments rotation and crystallographic twin-reorientation in an FSMA single crystal during the application of magnetic fields. Additionally, high-resolution neutron scattering measurements and first-principles calculations based on fully relativistic density functional theory are used to determine accurately the MCA for the compositionally disordered alloy of Ni 2Mn 1.14Ga 0.86. The results from these state-of-the-art experiments and calculations are self-consistently described within a phenomenological framework, which provides quantitative insights into the energetics of magnetostructural coupling in FSMAs. Based on the current model, the energy for magnetoelastic twin boundaries propagation for the studied alloy is estimated to be ~150kJ/m 3.« less

  16. Grafting of PMMA brushes layer on Cu surface to create a stable superhydrophobic surface

    NASA Astrophysics Data System (ADS)

    Zhang, Junhong; Cai, Junyan; Li, Ming

    2016-11-01

    In this paper, poly(methyl methacrylate) (PMMA) brushes were grafted on Cu micro-cone structured substrate by a simple one-step cathodic electro-initiated polymerization method which was carried out in aqueous solution at room temperature in the open air. The PMMA brushes were continuous, uniform and thickness-controllable, and it covalently bonded to the Cu surface. In the brushes, nitrophenyl moieties acted as cross-linker between PMMA chains. After removed from the solution followed by treated with water, the PMMA brushes (basically a hydrophilic material)/micro-cone structured Cu surface was hydrophilic with water contact angle (CA) of 74.4°. However, it exhibited superhydrophobicity by treating it in the acetone. The conversion from hydrophilic surface to superhydrophobic one may due to rearrangement of nitrophenyl moieties and PMMA chains at the topmost of the brushes. In addition, its water CA increased with grafting time of the brushes from 145° to about 166°, because there was no available space in thinner film for group reorientation. The surface was conversed to hydrophilic again after treated with hot water, but it was still superhydrophobic after treated in water at room temperature. This revealed that the group reorientation also easily occurred in hot water like in the acetone. More importantly, the surface retained good superhydrophobic stability in acidic environment and in long-time storage. Furthermore, the superhydrophobic surface had excellent resistance that can provide effective protection for the bare Cu substrate.

  17. Enhanced anatomical calibration in human movement analysis.

    PubMed

    Donati, Marco; Camomilla, Valentina; Vannozzi, Giuseppe; Cappozzo, Aurelio

    2007-07-01

    The representation of human movement requires knowledge of both movement and morphology of bony segments. The determination of subject-specific morphology data and their registration with movement data is accomplished through an anatomical calibration procedure (calibrated anatomical systems technique: CAST). This paper describes a novel approach to this calibration (UP-CAST) which, as compared with normally used techniques, achieves better repeatability, a shorter application time, and can be effectively performed by non-skilled examiners. Instead of the manual location of prominent bony anatomical landmarks, the description of which is affected by subjective interpretation, a large number of unlabelled points is acquired over prominent parts of the subject's bone, using a wand fitted with markers. A digital model of a template-bone is then submitted to isomorphic deformation and re-orientation to optimally match the above-mentioned points. The locations of anatomical landmarks are automatically made available. The UP-CAST was validated considering the femur as a paradigmatic case. Intra- and inter-examiner repeatability of the identification of anatomical landmarks was assessed both in vivo, using average weight subjects, and on bare bones. Accuracy of the identification was assessed using the anatomical landmark locations manually located on bare bones as reference. The repeatability of this method was markedly higher than that reported in the literature and obtained using the conventional palpation (ranges: 0.9-7.6 mm and 13.4-17.9, respectively). Accuracy resulted, on average, in a maximal error of 11 mm. Results suggest that the principal source of variability resides in the discrepancy between subject's and template bone morphology and not in the inter-examiner differences. The UP-CAST anatomical calibration could be considered a promising alternative to conventional calibration contributing to a more repeatable 3D human movement analysis.

  18. Three-Axis Time-Optimal Attitude Maneuvers of a Rigid-Body

    NASA Astrophysics Data System (ADS)

    Wang, Xijing; Li, Jisheng

    With the development trends for modern satellites towards macro-scale and micro-scale, new demands are requested for its attitude adjustment. Precise pointing control and rapid maneuvering capabilities have long been part of many space missions. While the development of computer technology enables new optimal algorithms being used continuously, a powerful tool for solving problem is provided. Many papers about attitude adjustment have been published, the configurations of the spacecraft are considered rigid body with flexible parts or gyrostate-type systems. The object function always include minimum time or minimum fuel. During earlier satellite missions, the attitude acquisition was achieved by using the momentum ex change devices, performed by a sequential single-axis slewing strategy. Recently, the simultaneous three-axis minimum-time maneuver(reorientation) problems have been studied by many researchers. It is important to research the minimum-time maneuver of a rigid spacecraft within onboard power limits, because of potential space application such as surveying multiple targets in space and academic value. The minimum-time maneuver of a rigid spacecraft is a basic problem because the solutions for maneuvering flexible spacecraft are based on the solution to the rigid body slew problem. A new method for the open-loop solution for a rigid spacecraft maneuver is presented. Having neglected all perturbation torque, the necessary conditions of spacecraft from one state to another state can be determined. There is difference between single-axis with multi-axis. For single- axis analytical solution is possible and the switching line passing through the state-space origin belongs to parabolic. For multi-axis, it is impossible to get analytical solution due to the dynamic coupling between the axes and must be solved numerically. Proved by modern research, Euler axis rotations are quasi-time-optimal in general. On the basis of minimum value principles, a research for reorienting an inertial syrnmetric spacecraft with time cost function from an initial state of rest to a final state of rest is deduced. And the solution to it is stated below: Firstly, the essential condition for solving the problem is deduced with the minimum value principle. The necessary conditions for optimality yield a two point boundary-value problem (TPBVP), which, when solved, produces the control history that minimize time performance index. In the nonsingular control, the solution is the' bang-bang maneuver. The control profile is characterized by Saturated controls for the entire maneuver. The singular control maybe existed. It is only singular in mathematics. According to physical principle, the bigger the mode of the control torque is, the shorter the time is. So saturated controls are used in singular control. Secondly, the control parameters are always in maximum, so the key problem is to determine switch point thus original problem is changed to find the changing time. By the use of adjusting the switch on/off time, the genetic algorithm, which is a new robust method is optimized to determine the switch features without the gyroscopic coupling. There is improvement upon the traditional GA in this research. The homotopy method to find the nonlinear algebra is based on rigorous topology continuum theory. Based on the idea of the homotopy, the relaxation parameters are introduced, and the switch point is figured out with simulated annealing. Computer simulation results using a rigid body show that the new method is feasible and efficient. A practical method of computing approximate solutions to the time-optimal control- switch times for rigid body reorientation has been developed.

  19. Reversal magnetization, spin reorientation, and exchange bias in YCr O3 doped with praseodymium

    NASA Astrophysics Data System (ADS)

    Durán, A.; Escamilla, R.; Escudero, R.; Morales, F.; Verdín, E.

    2018-01-01

    Crystal structure, thermal properties, and magnetic properties were studied systematically in Y1 -xP rxCr O3 with 0.0 ≤x ≤0.3 compositions. Magnetic susceptibility and specific-heat measurements show an increase in the antiferromagnetic transition temperature (TN) as Pr is substituted in the Y sites and notable magnetic features are observed below TN. Strong coupling between magnetic and crystalline parameters is observed in a small range of Pr compositions. A small perturbation in the lattice parameters by a Pr ion is sufficient to induce a spin-reorientation transition followed by magnetization reversal to finally induce the exchange-bias effect. The spin-reorientation temperature (TSR) is increased from 35 to 149 K for 0.025 ≤x ≤0.1 compositions. It is found that the Cr spin sublattice rotates continuously from TSR to a new spin configuration at lower temperature. In addition, magnetization reversal is observed at T*˜35 K for x =0.05 up to T*˜63 K for x =0.20 composition. The M -H curves show a negative exchange-bias effect induced by Pr ions, which are observed below 100 K and are more intense at 5 K. At 10 K, the magnetic contribution of the specific heat as well as the ZFC magnetization show the rise of a peak with increasing Pr content. The magnetic anomaly could be associated with the freezing of the Pr magnetic moment randomly distributed at the 4 c crystallographic site. A clear correspondence between spin reorientation, magnetization reversal, and exchange-bias anisotropy with the tilting and octahedral distortion is also discussed.

  20. Cyclic stretch-induced stress fiber dynamics - Dependence on strain rate, Rho-kinase and MLCK

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Chin-Fu; Haase, Candice; Deguchi, Shinji

    2010-10-22

    Research highlights: {yields} Cyclic stretch induces stress fiber disassembly, reassembly and fusion perpendicular to the direction of stretch. {yields} Stress fiber disassembly and reorientation were not induced at low stretch frequency. {yields} Stretch caused actin fiber formation parallel to stretch in distinct locations in cells treated with Rho-kinase and MLCK inhibitors. -- Abstract: Stress fiber realignment is an important adaptive response to cyclic stretch for nonmuscle cells, but the mechanism by which such reorganization occurs is not known. By analyzing stress fiber dynamics using live cell microscopy, we revealed that stress fiber reorientation perpendicular to the direction of cyclic uniaxialmore » stretching at 1 Hz did not involve disassembly of the stress fiber distal ends located at focal adhesion sites. Instead, these distal ends were often used to assemble new stress fibers oriented progressively further away from the direction of stretch. Stress fiber disassembly and reorientation were not induced when the frequency of stretch was decreased to 0.01 Hz, however. Treatment with the Rho-kinase inhibitor (Y27632) reduced stress fibers to thin fibers located in the cell periphery which bundled together to form thick fibers oriented parallel to the direction of stretching at 1 Hz. In contrast, these thin fibers remained diffuse in cells subjected to stretch at 0.01 Hz. Cyclic stretch at 1 Hz also induced actin fiber formation parallel to the direction of stretch in cells treated with the myosin light chain kinase (MLCK) inhibitor ML-7, but these fibers were located centrally rather than peripherally. These results shed new light on the mechanism by which stress fibers reorient in response to cyclic stretch in different regions of the actin cytoskeleton.« less

  1. Communication: Heterogeneous water dynamics on a clathrate hydrate lattice detected by multidimensional oxygen nuclear magnetic resonance

    NASA Astrophysics Data System (ADS)

    Adjei-Acheamfour, Mischa; Storek, Michael; Böhmer, Roland

    2017-05-01

    Previous deuteron nuclear magnetic resonance studies revealed conflicting evidence regarding the possible motional heterogeneity of the water dynamics on the hydrate lattice of an ice-like crystal. Using oxygen-17 nuclei as a sensitive quadrupolar probe, the reorientational two-time correlation function displays a clear nonexponentiality. To check whether this dispersive behavior is a consequence of dynamic heterogeneity or rather of an intrinsic nonexponentiality, a multidimensional, four-time magnetic resonance experiment was devised that is generally applicable to strongly quadrupolarly perturbed half-integer nuclei such as oxygen-17. Measurements of an appropriate four-time function demonstrate that it is possible to select a subensemble of slow water molecules. Its mean time scale is compared to theoretical predictions and evidence for significant motional heterogeneity is found.

  2. Expanded Safety and Efficacy Data for a New Method of Performing Electroconvulsive Therapy

    PubMed Central

    Sahlem, Gregory L.; Short, E. Baron; Kerns, Suzanne; Snipes, Jon; DeVries, William; Fox, James B.; Burns, Carol; Schmidt, Matthew; Nahas, Ziad H.; George, Mark S.; Sackeim, Harold A.

    2016-01-01

    Objective Electroconvulsive therapy (ECT) is the most rapid and effective antidepressant treatment but with concerns about cognitive adverse effects. A new form of ECT, focal electrically administered seizure therapy (FEAST), was designed to increase the focality of stimulation and better match stimulus parameters with neurophysiology. We recently reported on the safety and feasibility of FEAST in a cohort (n = 17) of depressed patients. We now report on the safety, feasibility, preliminary efficacy, and cognitive effects of FEAST in a new cohort. Methods Open-label FEAST was administered to 20 depressed adults (6 men; 3 with bipolar disorder; age 49.1 ± 10.6 years). Clinical and cognitive assessments were obtained at baseline and end of course. Time to orientation recovery was assessed at each treatment. Nonresponders switched to conventional ECT. Results Participants tolerated the treatment well with no dropouts. Five patients (25%) transitioned from FEAST to conventional ECT due to inadequate response. After FEAST (mean, 9.3 ± 3.5 sessions; range, 4–14), there was a 58.1% ± 36.0% improvement in Hamilton Rating Scale for Depression scores compared with that in the baseline (P < 0.0001); 13 (65%) of 20 patients met response criteria, and 11 (55%) of 20 met remission criteria. Patients achieved reorientation (4 of 5 items) in 4.4 ± 3.0 minutes (median, 4.5 minutes), timed from eyes opening. There was no deterioration in neuropsychological measures. Conclusions These findings provide further support for the safety and efficacy of FEAST. The remission and response rates were in the range found using conventional ECT, and the time to reorientation may be quicker. However, without a randomized comparison group, conclusions are tentative. PMID:27379790

  3. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059344 (10 July 2014) --- In the International Space Station’s Kibo laboratory, NASA astronaut Reid Wiseman (left) and European Space Agency astronaut Alexander Gerst, both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  4. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059467 (10 July 2014) --- In the International Space Station's Kibo laboratory, European Space Agency astronaut Alexander Gerst and NASA astronaut Reid Wiseman (mostly obscured), both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  5. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059478 (10 July 2014) --- In the International Space Station's Kibo laboratory, European Space Agency astronaut Alexander Gerst (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  6. An acoustic on-chip goniometer for room temperature macromolecular crystallography.

    PubMed

    Burton, C G; Axford, D; Edwards, A M J; Gildea, R J; Morris, R H; Newton, M I; Orville, A M; Prince, M; Topham, P D; Docker, P T

    2017-12-05

    This paper describes the design, development and successful use of an on-chip goniometer for room-temperature macromolecular crystallography via acoustically induced rotations. We present for the first time a low cost, rate-tunable, acoustic actuator for gradual in-fluid sample reorientation about varying axes and its utilisation for protein structure determination on a synchrotron beamline. The device enables the efficient collection of diffraction data via a rotation method from a sample within a surface confined droplet. This method facilitates efficient macromolecular structural data acquisition in fluid environments for dynamical studies.

  7. Direct evidence of detwinning in polycrystalline Ni-Mn-Ga ferromagnetic shape memory alloys during deformation.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nie, Z. H.; Lin Peng, R.; Johansson, S.

    2008-01-01

    In situ time-of-flight neutron diffraction and high-energy x-ray diffraction techniques were used to reveal the preferred reselection of martensite variants through a detwinning process in polycrystalline Ni-Mn-Ga ferromagnetic shape memory alloys under uniaxial compressive stress. The variant reorientation via detwinning during loading can be explained by considering the influence of external stress on the grain/variant orientation-dependent distortion energy. These direct observations of detwinning provide a good understanding of the deformation mechanisms in shape memory alloys.

  8. Thermocapillary reorientation of Janus drops

    NASA Astrophysics Data System (ADS)

    Rosales, Rodolfo; Saenz, Pedro

    2017-11-01

    Janus drops, named after the Ancient Roman two-faced god, are liquid drops formed from two immiscible fluids. Experimental observations indicate that a Janus drop may re-orientate in response to an applied external thermal gradient due to the Marangoni effect. Depending on the angle between the interior interface and the direction of the temperature gradient, disparities in the physical properties of the constituent liquids may lead to asymmetries in the thermocapillary flow. As a result, the drop will move along a curved path until a torque-free configuration is achieved, point after which it will continue on a straight trajectory. Here, we present the results of a theoretical investigation of this realignment phenomenon in the Stokes regime and in the limit of non-deformable interfaces. A 3D semi-analytical method in terms of polar spherical harmonics is developed to characterize and rationalize the hydrodynamic response (forces and torques), flow (velocity and temperature distribution) and trajectory of a Janus drop moving during the temperature-driven reorientation process. Furthermore, we discuss how this phenomenon may be exploited to develop dynamically reconfigurable micro-lenses. This work was partially supported by the US National Science Foundation through Grants DMS-1614043 and DMS-1719637.

  9. Symmetry-lowering lattice distortion at the spin reorientation in MnBi single crystals

    DOE PAGES

    McGuire, Michael A.; Cao, Huibo; Chakoumakos, Bryan C.; ...

    2014-11-18

    Here we report structural and physical properties determined by measurements on large single crystals of the anisotropic ferromagnet MnBi. The findings support the importance of magnetoelastic effects in this material. X-ray diffraction reveals a structural phase transition at the spin reorientation temperature T SR = 90 K. The distortion is driven by magneto-elastic coupling, and upon cooling transforms the structure from hexagonal to orthorhombic. Heat capacity measurements show a thermal anomaly at the crystallographic transition, which is suppressed rapidly by applied magnetic fields. Effects on the transport and anisotropic magnetic properties of the single crystals are also presented. Increasing anisotropymore » of the atomic displacement parameters for Bi with increasing temperature above T SR is revealed by neutron diffraction measurements. It is likely that this is directly related to the anisotropic thermal expansion in MnBi, which plays a key role in the spin reorientation and magnetocrystalline anisotropy. Finally, the identification of the true ground state crystal structure reported here may be important for future experimental and theoretical studies of this permanent magnet material, which have to date been performed and interpreted using only the high temperature structure.« less

  10. Reorienting in Virtual 3D Environments: Do Adult Humans Use Principal Axes, Medial Axes or Local Geometry?

    PubMed Central

    Ambosta, Althea H.; Reichert, James F.; Kelly, Debbie M.

    2013-01-01

    Studies have shown that animals, including humans, use the geometric properties of environments to orient. It has been proposed that orientation is accomplished primarily by encoding the principal axes (i.e., global geometry) of an environment. However, recent research has shown that animals use local information such as wall length and corner angles as well as local shape parameters (i.e., medial axes) to orient. The goal of the current study was to determine whether adult humans reorient according to global geometry based on principal axes or whether reliance is on local geometry such as wall length and sense information or medial axes. Using a virtual environment task, participants were trained to select a response box located at one of two geometrically identical corners within a featureless rectangular-shaped environment. Participants were subsequently tested in a transformed L-shaped environment that allowed for a dissociation of strategies based on principal axes, medial axes and local geometry. Results showed that participants relied primarily on a medial axes strategy to reorient in the L-shaped test environment. Importantly, the search behaviour of participants could not be explained by a principal axes-based strategy. PMID:24223869

  11. Quadratic electroabsorption studies of molecular motion in dye-doped polymers

    NASA Astrophysics Data System (ADS)

    Poga, Constantina; Kuzyk, Mark G.; Dirk, Carl W.

    1993-02-01

    This paper reports on quadratic electroabsorption studies of thin-film solid solutions of squarylium dye molecules in poly(methylmethacrylate) polymer with the aim of understanding the role of electronic and reorientational mechanisms in the third-order nonlinear-optical susceptibility. We present a generalized theory of the quadratic electrooptic response that includes both electronic mechanisms and molecular reorientation and show that the ratio of two independent third-order susceptibility tensor components, namely (chi) (3)3333/(chi) (3)1133, determines the relative contribution of each mechanism. Based on these theoretical results, we have designed and built an experiment that determines this ratio as a function of temperature and wavelength. Results show that at room temperature and near the first electronic transition wavelength, the response is dominated by the electronic mechanism, and that the reorientational contribution dominates when the sample is heated above its glass transition temperature. Furthermore, results show that, off-resonance, the sign of the imaginary part of the third-order susceptibility is positive. Quadratic electroabsorption is thus shown to be a versatile tool for measuring the imaginary part of the third-order nonlinear-optical susceptibility which yields information about the interaction of polymer and dopant molecule.

  12. Mechanism of dynamic reorientation of cortical microtubules due to mechanical stress.

    PubMed

    Muratov, Alexander; Baulin, Vladimir A

    2015-12-01

    Directional growth caused by gravitropism and corresponding bending of plant cells has been explored since 19th century, however, many aspects of mechanisms underlying the perception of gravity at the molecular level are still not well known. Perception of gravity in root and shoot gravitropisms is usually attributed to gravisensitive cells, called statocytes, which exploit sedimentation of macroscopic and heavy organelles, amyloplasts, to sense the direction of gravity. Gravity stimulus is then transduced into distal elongation zone, which is several mm far from statocytes, where it causes stretching. It is suggested that gravity stimulus is conveyed by gradients in auxin flux. We propose a theoretical model that may explain how concentration gradients and/or stretching may indirectly affect the global orientation of cortical microtubules, attached to the cell membrane and induce their dynamic reorientation perpendicular to the gradients. In turn, oriented microtubule arrays direct the growth and orientation of cellulose microfibrils, forming part of the cell external skeleton and determine the shape of the cell. Reorientation of microtubules is also observed in reaction to light in phototropism and mechanical bending, thus suggesting universality of the proposed mechanism. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. I. Depolarized Light Scattering Studies of Rotational - Coupling in Liquids Composed of Small Anisotropic Molecules. I. Investigation of the Coupling Between Reorientation and Longitudinal Modes in the Brillouin Spectra of Liquids Composed of Anisotropic Molecules.

    NASA Astrophysics Data System (ADS)

    O'Steen, Byron Lance

    Part I. In an attempt to better understand the molecular interactions governing the behaviour of the coupling parameter R measured in light scattering experiments, the depolarized (I(,vh)) spectra for a series of liquids composed of small aromatic molecules, very similar in size and shape, have been measured. The molecules studied here were generally monosubstituted benzene and pyridine derivatives. All were found to exhibit the doublet structure indicative of dynamic coupling between molecular reorientation and shear modes, or more simply, rotational-translational coupling. The degree of this coupling is measured by a parameter R(O(LESSTHEQ) R(LESSTHEQ) 1) which is often though of as the fraction of the shear viscosity attributable to reorientational motion. From the depolarized spectra the coupling parameter R, collective reorientation frequency, and low frequency shear viscosity were determined. The values of R were found to vary from 0.24 to 0.55 for the liquids studied here. This range is nearly as broad as that observed in all previous studies, which have included such diverse molecules as carbon disulfide, tri-phenyl phosphite, and the highly anisotropic liquid crystal MBBA. This suggests that size and shape considerations, or steric forces, are not the primary factor in determining the degree of rotational-translational coupling as measured by light scattering. If this is indeed the case then other non-steric interactions must be producing the observed variation in R. With this in mind, we have examined possible electrostatic interactions. A simple correlation with dipole moment was not found to exist. Instead it appears that the variation in R can only be understood by consideration of the detailed molecular charge distribution. This is determined to a large extent by resonance interactions with the aromatic ring which are generally reflected in the change of dipole moment from the aliphatic compound (CH(,3)-R) to its aromatic analog (C(,6)H(,5)-R). Based upon resonance structure arguments and our own experimental results, it is concluded that the anomolously large R values found for pyridine from the I(,HH) depolarized spectrum might well be correct and the more orthodox I(,VH) measurements in error. If this assertion is indeed correct, then the reliability of rotational-translational coupling measurements by I(,VH) depolarized light scattering must be considered questionable for weakly scattering molecules such as pyridine. Part II. The coupling of reorientational motion to longitudinal modes was investigated by studying the Brillouin spectra of aniline and p-anisaldehyde over a wide range of scattering angles. The primary goal of these studies was to attempt to confirm the microscopic theory of orientational relaxation in the polarized spectrum. Theoretically it has been shown that for symmetric tops the coupling between longitudinal modes and reorientation in the polarized spectrum is identical to that between shear modes and reorientation in the depolarized spectrum. Thus the Brillouin scattering studies performed here also provide an internal check on the consistency of the 2-variable molecular theory for depolarized scattering and the corresponding theory of orientational relaxation in the Brillouin spectrum. Aniline and p-anisaldehyde were chosen for this investigation since their depolarized spectra at the temperature of interest are well described by the simple 2-variable molecular theory coupling shear modes to orientation. The collective reorientation frequency for both liquids could easily be varied in the low gigahertz range by operating at temperatures near the freezing point. Thus the effects of orientational relaxation in the propagation of longitudinal waves (1-10 GHz) should be observable in an angular study of the Brillouin spectra. Moderate viscosites and large rotational-translational couplings also made these liquids attractive from an experimental standpoint since these quantities determine the relaxation strength. Our strengths for attenuation and velocity of the longitudinal waves demonstrate that there is indeed relaxation in the shear viscosity as predicted by theory. However, shear relaxation in addition to that due to reorientational motion is indicated by the (kappa)-dependence of the attenuation results. This stands as an apparent contradiction to the depolarized results which suggest that only orientational relaxation should be important under these conditions. Since the different relaxation effects cannot be unambiguously separated here, a detailed confirmation of orientational relaxation theory could not be obtained.

  14. [Formula: see text]A longitudinal analysis of the attention networks in 6- to 11-year-old children.

    PubMed

    Lewis, Frances C; Reeve, Robert A; Johnson, Katherine A

    2018-02-01

    Attention is critical for everyday functioning. Posner and Petersen's model of attention describes three neural networks involved in attention control-the alerting network for arousal, the orienting network for selecting sensory input and reorienting attention, and the executive network for the regulatory control of attention. No longitudinal research has examined relative change in these networks in children. A modified version of the attention network task (ANT) was used to examine changes in the three attention networks, three times over 12 months, in 114 6-, 8- and 10-year-olds. Findings showed that the alerting network continued to develop over this period, the orienting network had stabilized by 6 years, and the conflict network had largely stabilized by 7 years. The reorienting of attention was also assessed using invalid cues, which showed a similar developmental trajectory to the orienting attention network and had stabilized by 6 years. The results confirm that age 6 to 7 years is a critical period in the development of attention, in particular executive attention. The largest improvement over the evaluation period was between 6 and 7 years; however, subtle changes were found in attention beyond 8 years of age.

  15. Accumulation of actin in subsets of pioneer growth cone filopodia in response to neural and epithelial guidance cues in situ

    PubMed Central

    1993-01-01

    Directed outgrowth of neural processes must involve transmission of signals from the tips of filopodia to the central region of the growth cone. Here, we report on the distribution and dynamics of one possible element in this process, actin, in live growth cones which are reorienting in response to in situ guidance cues. In grasshopper embryonic limbs, pioneer growth cones respond to at least three types of guidance cues: a limb axis cue, intermediate target cells, and a circumferential band of epithelial cells. With time-lapse imaging of intracellularly injected rhodamine-phalloidin and rhodamine-actin, we monitored the distribution of actin during growth cone responses to these cues. In distal limb regions, accumulation of actin in filopodia and growth cone branches accompanies continued growth, while reduction of actin accompanies withdrawal. Where growth cones are reorienting to intermediate target cells, or along the circumferential epithelial band, actin selectively accumulates in the proximal regions of those filopodia that have contacted target cells or are extending along the band. Actin accumulations can be retrogradely transported along filopodia, and can extend into the central region of the growth cone. These results suggest that regulation and translocation of actin may be a significant element in growth cone steering. PMID:8227150

  16. Reduced gravitropism in hypocotyls of starch-deficient mutants of Arabidopsis

    NASA Technical Reports Server (NTRS)

    Kiss, J. Z.; Guisinger, M. M.; Miller, A. J.; Stackhouse, K. S.

    1997-01-01

    Gravitropism was examined in dark- and light-grown hypocotyls of wild-type (WT), two reduced starch mutants (ACG 20 and ACG 27), and a starchless mutant (ACG 21) of Arabidopsis. In addition, the starch content of these four strains was studied with light and electron microscopy. Based on time course of curvature and orientation studies, the graviresponse in hypocotyls is proportional to the amount of starch in a genotype. Furthermore, starch mutations seem to primarily affect gravitropism rather than differential growth since both phototropic curvature and growth rates among the four genotypes are approximately equal. Our results suggest that gravity perception may require a greater plastid mass in hypocotyls compared to roots. The kinetics of gravitropic curvature also was compared following reorientation at 45 degrees, 90 degrees, and 135 degrees. As has been reported for other plant species, the optimal angle of reorientation is 135 degrees for WT Arabidopsis and the two reduced starch mutants, but the magnitude of curvature of the starchless mutant appears to be independent of the initial angle of displacement. Taken together, the results of the present study and our previous experiments with roots of the same four genotypes [Kiss et al. (1996) Physiol. Plant. 97: 237] support a plastid-based hypothesis for gravity perception in plants.

  17. Adaptation of orientation vectors of otolith-related central vestibular neurons to gravity.

    PubMed

    Eron, Julia N; Cohen, Bernard; Raphan, Theodore; Yakushin, Sergei B

    2008-09-01

    Behavioral experiments indicate that central pathways that process otolith-ocular and perceptual information have adaptive capabilities. Because polarization vectors of otolith afferents are directly related to the electro-mechanical properties of the hair cell bundle, it is unlikely that they change their direction of excitation. This indicates that the adaptation must take place in central pathways. Here we demonstrate for the first time that otolith polarization vectors of canal-otolith convergent neurons in the vestibular nuclei have adaptive capability. A total of 10 vestibular-only and vestibular-plus-saccade neurons were recorded extracellularly in two monkeys before and after they were in side-down positions for 2 h. The spatial characteristics of the otolith input were determined from the response vector orientation (RVO), which is the projection of the otolith polarization vector, onto the head horizontal plane. The RVOs had no specific orientation before animals were in side-down positions but moved toward the gravitational axis after the animals were tilted for extended periods. Vector reorientations varied from 0 to 109 degrees and were linearly related to the original deviation of the RVOs from gravity in the position of adaptation. Such reorientation of central polarization vectors could provide the basis for changes in perception and eye movements related to prolonged head tilts relative to gravity or in microgravity.

  18. Behavior learning in differential games and reorientation maneuvers

    NASA Astrophysics Data System (ADS)

    Satak, Neha

    The purpose of this dissertation is to apply behavior learning concepts to incomplete- information continuous time games. Realistic game scenarios are often incomplete-information games in which the players withhold information. A player may not know its opponent's objectives and strategies prior to the start of the game. This lack of information can limit the player's ability to play optimally. If the player can observe the opponent's actions, it can better optimize its achievements by taking corrective actions. In this research, a framework to learn an opponent's behavior and take corrective actions is developed. The framework will allow a player to observe the opponent's actions and formulate behavior models. The developed behavior model can then be utilized to find the best actions for the player that optimizes the player's objective function. In addition, the framework proposes that the player plays a safe strategy at the beginning of the game. A safe strategy is defined in this research as a strategy that guarantees a minimum pay-off to the player independent of the other player's actions. During the initial part of the game, the player will play the safe strategy until it learns the opponent's behavior. Two methods to develop behavior models that differ in the formulation of the behavior model are proposed. The first method is the Cost-Strategy Recognition (CSR) method in which the player formulates an objective function and a strategy for the opponent. The opponent is presumed to be rational and therefore will play to optimize its objective function. The strategy of the opponent is dependent on the information available to the opponent about other players in the game. A strategy formulation presumes a certain level of information available to the opponent. The previous observations of the opponent's actions are used to estimate the parameters of the formulated behavior model. The estimated behavior model predicts the opponent's future actions. The second method is the Direct Approximation of Value Function (DAVF) method. In this method, unlike the CSR method, the player formulates an objective function for the opponent but does not formulates a strategy directly; rather, indirectly the player assumes that the opponent is playing optimally. Thus, a value function satisfying the HJB equation corresponding to the opponent's cost function exists. The DAVF method finds an approximate solution for the value function based on previous observations of the opponent's control. The approximate solution to the value function is then used to predict the opponent's future behavior. Game examples in which only a single player is learning its opponent's behavior are simulated. Subsequently, examples in which both players in a two-player game are learning each other's behavior are simulated. In the second part of this research, a reorientation control maneuver for a spinning spacecraft will be developed. This will aid the application of behavior learning and differential games concepts to the specific scenario involving multiple spinning spacecraft. An impulsive reorientation maneuver with coasting will be analytically designed to reorient the spin axis of the spacecraft using a single body fixed thruster. Cooperative maneuvers of multiple spacecraft optimizing fuel and relative orientation will be designed. Pareto optimality concepts will be used to arrive at mutually agreeable reorientation maneuvers for the cooperating spinning spacecraft.

  19. Rotational dynamics of imidazolium-based ionic liquids: do the nature of the anion and the length of the alkyl chain influence the dynamics?

    PubMed

    Prabhu, Sugosh R; Dutt, G B

    2014-11-20

    The rotational dynamics of 1-alkyl-3-methylimidazolium-based ionic liquids has been investigated by monitoring their inherent fluorescence with the intent to unravel the characteristics of the emitting species. For this purpose, temperature-dependent fluorescence anisotropies of 1-alkyl-3-methylimidazolium (alkyl = ethyl and hexyl) ionic liquids with anions such as tris(pentafluoroethyl)trifluorophosphate ([FAP]), bis(trifluoromethylsulfonyl)imide ([Tf2N]), tetrafluoroborate ([BF4]), and hexafluorophosphate ([PF6]) have been measured. It has been observed that the reorientation times (τr) of the ionic liquids with an ethyl chain scale linearly with viscosity and were found to be independent of the nature of the anion. The experimentally measured τr values are a factor of 3 longer than the ones calculated for 1-ethyl-3-methylimidazolium cation using the Stokes-Einstein-Debye (SED) hydrodynamic theory with stick boundary condition, which suggests that the emitting species is not the imidazolium moiety but some kind of associated species. The reorientation times of ionic liquids with a hexyl chain, in contrast, follow the trend τr([FAP]) > τr([Tf2N]) = τr([BF4]) > τr([PF6]) at a given viscosity (η) and temperature (T). The ability of the ionic liquids with longer alkyl chains to form the organized structure appears to be responsible for the observed behavior considering the fact that significant deviations from linearity have been noticed in the τr versus η/T plots for strongly associating anions [BF4] and [PF6], especially at ambient temperatures.

  20. An evaluation of a public health nutrition workforce development intervention for the nutrition and dietetics workforce.

    PubMed

    Palermo, C; Hughes, R; McCall, L

    2010-06-01

    Workforce development is a key element for building the capacity to effectively address priority population nutrition issues. On-the-job learning and mentoring have been proposed as strategies for practice improvement in public health nutrition; however, there is limited evidence for their effectiveness. An evaluation of a mentoring circle workforce development intervention was undertaken. Thirty-two novice public health nutritionists participated in one of three mentoring circles for 2 h, every 6 weeks, over a 7-month period. Pre- and post-intervention qualitative (questionnaire, interview, mentor diary) and quantitative (competence, time working in public health nutrition) data were collected. The novice public health nutritionists explained the intervention facilitated sharing of ideas and strategies and promoted reflective practice. They articulated the important attributes of the mentor in the intervention as having experience in and a passion for public health, facilitating a trusting relationship and providing effective feedback. Participants reported a gain in competency and had an overall mean increase in self-reported competence of 15% (range 3-48% change; P < 0.05) across a broad range of competency elements. Many participants described re-orienting their practice towards population prevention, with quantifiable increases in work time allocated to preventive work post-intervention. Mentoring supported service re-orientation and competency development in public health nutrition. The nature of the group learning environment and the role and qualities of the mentor were important elements contributing to the interventions effects. Mentoring circles offer a potentially effective strategy for workforce development in nutrition and dietetics.

  1. Prospective-pricing strategies for hospital and departmental effectiveness: the physician's response.

    PubMed

    Shapleigh, C

    1985-10-01

    Physician-practice patterns are discussed, and programs of decentralization designed to reduce ancillary use are described. The New England Medical Center (NEMC) conducted a study with two other major hospitals in Boston comparing physician-practice patterns for patients who had had carotid endarterectomies. The indications for surgery for these patients did not appear to be different among the hospitals; however, average charges and length of stay varied considerably. Operating-room time and postoperative management also varied substantially. Strategies to change physician-practice patterns must address the issues of incentives to physicians and hospitals. At NEMC, a program of decentralization is being implemented that involves physician participation in budgeting hospital resources. A program of product pricing has been developed, whereby the NEMC offers an HMO a fixed price for certain kinds of cases upon admission. A daily use report was started to report resource use for specific cases compared with annual medians for that type of case. Case types from many different surgical specialties are involved. The reports show physicians the difference between the actual and expected costs in terms of variances. The NEMC has reoriented its budgeting process to include clinical divisions. Clinical services are planning to budget the use of intermediate products across different cost centers. The clinical budgeting program makes the planning process more objective, lowers the use of ancillary services, and reduces costs.

  2. Analysis of the trajectory of Drosophila melanogaster in a circular open field arena.

    PubMed

    Valente, Dan; Golani, Ilan; Mitra, Partha P

    2007-10-24

    Obtaining a complete phenotypic characterization of a freely moving organism is a difficult task, yet such a description is desired in many neuroethological studies. Many metrics currently used in the literature to describe locomotor and exploratory behavior are typically based on average quantities or subjectively chosen spatial and temporal thresholds. All of these measures are relatively coarse-grained in the time domain. It is advantageous, however, to employ metrics based on the entire trajectory that an organism takes while exploring its environment. To characterize the locomotor behavior of Drosophila melanogaster, we used a video tracking system to record the trajectory of a single fly walking in a circular open field arena. The fly was tracked for two hours. Here, we present techniques with which to analyze the motion of the fly in this paradigm, and we discuss the methods of calculation. The measures we introduce are based on spatial and temporal probability distributions and utilize the entire time-series trajectory of the fly, thus emphasizing the dynamic nature of locomotor behavior. Marginal and joint probability distributions of speed, position, segment duration, path curvature, and reorientation angle are examined and related to the observed behavior. The measures discussed in this paper provide a detailed profile of the behavior of a single fly and highlight the interaction of the fly with the environment. Such measures may serve as useful tools in any behavioral study in which the movement of a fly is an important variable and can be incorporated easily into many setups, facilitating high-throughput phenotypic characterization.

  3. Origin of spin reorientation transitions in antiferromagnetic MnPt-based alloys

    NASA Astrophysics Data System (ADS)

    Chang, P.-H.; Zhuravlev, I. A.; Belashchenko, K. D.

    2018-04-01

    Antiferromagnetic MnPt exhibits a spin reorientation transition (SRT) as a function of temperature, and off-stoichiometric Mn-Pt alloys also display SRTs as a function of concentration. The magnetocrystalline anisotropy in these alloys is studied using first-principles calculations based on the coherent potential approximation and the disordered local moment method. The anisotropy is fairly small and sensitive to the variations in composition and temperature due to the cancellation of large contributions from different parts of the Brillouin zone. Concentration and temperature-driven SRTs are found in reasonable agreement with experimental data. Contributions from specific band-structure features are identified and used to explain the origin of the SRTs.

  4. Early mammalian development under conditions of reorientation relative to the gravity vector

    NASA Technical Reports Server (NTRS)

    Wolgemuth, D. J.; Grills, G. S.

    1985-01-01

    A clinostat was used to assess the effects of reorientation relative to the gravity vector on mammalian germ cells cultured in vitro. Previous studies using this system revealed an inhibition of meiotic maturation of mouse oocytes. In the present study, the effects of clinostat rotation on in vitro fertilization were examined. The frequency of fertilization of experimental cultures did not vary from that of the clinostat vertical control cultures at either of the rotation rates examined. Importantly, no abnormalities of fertilization, such as parthenogenetic activation, fragmentation, or polyspermy were seen. It is concluded that the initial events of fertilization were unaffected by this treatment, although the developmental potential of these embryos remains to be assessed.

  5. Role of space charges on light-induced effects in nematic liquid crystals doped by methyl red.

    PubMed

    Lucchetti, L; Simoni, F

    2014-03-01

    We show that both the extraordinarily large nonlinear response and the light-induced permanent reorientation in liquid crystals doped by the azo dye methyl red originates from the same phenomenon of modification of the charge density on the irradiated surface. The demonstration is done by applying ac voltage to the samples, showing that in this case no permanent anchoring is possible. The measurements confirm the role of photoisomerization that gives a transient contribution to the actual reorientation process only in the high dose regime. This result allows us to draw a picture for light-induced effects that might be applied to a large class of compounds.

  6. Thickness driven spin reorientation transition of epitaxial LaCrO3 films

    NASA Astrophysics Data System (ADS)

    Park, Junho; Kim, Dong-Hwan; Lee, Doopyo; Ko, Kyung-Tae; Hyun Song, Jong; Kim, Jae-Young; Koo, Tae-Yeong; Lee, Seung Ran; Park, Jae-Hoon

    2018-03-01

    We grew fully strained epitaxial LaCrO3 (LCO) films on SrTiO3(001) under layer-by-layer control up to the film thickness of t = 130 nm using a pulsed laser deposition method. The spin axis of the antiferromagnetic LCO film was systematically examined as a function of t by using Cr L2,3-edge x-ray magnetic linear dichroism (XMLD). The XMLD results manifest a spin reorientation transition (SRT) across a transition thickness of tT ˜ 60 nm. This SRT is well explained in terms of two competing magnetic anisotropy energies of the surface/interface (KS) and the LCO film itself (KV).

  7. Structural relaxation processes in polyethylene glycol/CCl4 solutions by Brillouin scattering.

    PubMed

    Pochylski, M; Aliotta, F; Błaszczak, Z; Gapiński, J

    2005-03-10

    We present results of a Brillouin scattering experiment on solutions of poly(ethylene glycol) of mean molecular mass 600 g/mol (PEG600) in CCl4. The relaxation process detected has been assigned to conformational rearrangements of the polymeric chains, triggered by reorientation of the side groups. The concentration dependencies of the hypersound velocity and normalized absorption are compared against the indications from several models proposed in the literature. The concentration evolution of the system is described in terms of two distinct regimes. At high polymer content, the system is dominated by the structure of the dense polymer, where polymer-polymer interactions, together with excluded volume effects, induce the existence of a preferred local arrangement resulting in a narrow distribution of the relaxation times, with the average value of the relaxation time following a simple Arrhenius temperature dependence. As the concentration decreases, the original structure of the hydrogen bonded polymer network is destroyed, and a number of different local configuration coexist, giving rise to a wider distribution of relaxation times or to a multiple relaxation. At low concentrations, the experimental data are well fitted assuming a Vogel-Fulker-Tammon behavior for the average relaxation time. In addition, the observed deviation from the ideal behavior for the refractive index and the density suggests that CCl4 does not behave as an inert solvent, and due to polarization effects, it can develop local hetero-associated structures via electrostatic interaction with the O-H end groups of the polymeric chains. The hypothesis has been successfully tested by fitting the concentration behavior of the hypersonic velocity to a recent three-component model, suitable to describe the concentration dependence of sound velocity in moderately interacting fluids. The indication of the model furnishes a very high value for the association constant of the PEG600, confirming the literature indication that, in polymeric systems capable of developing long liner aggregates via hydrogen bonding interaction, the Brillouin probe is insensitive to the true length of the polymeric chains. The Brillouin scattering experiment just sees an effective hydrogen bonded aggregate that is huge relative to the length of the single polymeric chain and becomes sensitive only to the density fluctuations of the local segmental motions.

  8. Spatial Temperature Mapping within Polymer Nanocomposites Undergoing Ultrafast Photothermal Heating via Gold Nanorods

    PubMed Central

    Maity, Somsubhra; Wu, Wei-Chen; Xu, Chao; Tracy, Joseph B.; Gundogdu, Kenan; Bochinski, Jason R.; Clarke, Laura I.

    2015-01-01

    Heat emanates from gold nanorods (GNRs) under ultrafast optical excitation of the localized surface plasmon resonance. The steady state nanoscale temperature distribution formed within a polymer matrix embedded with GNRs undergoing pulsed femtosecond photothermal heating is determined experimentally using two independent ensemble optical techniques. Physical rotation of the nanorods reveals the average local temperature of the polymer melt in the immediate spatial volume surrounding them while fluorescence of homogeneously-distributed perylene molecules monitors temperature over sample regions at larger distances from the GNRs. Polarization-sensitive fluorescence measurements of the perylene probes provide an estimate of the average size of the quasi-molten region surrounding each nanorod (that is, the boundary between softened polymer and solid material as the temperature decreases radially away from each particle) and distinguishes the steady state temperature in the solid and melt regions. Combining these separate methods enables nanoscale spatial mapping of the average steady state temperature distribution caused by ultrafast excitation of the GNRs. These observations definitively demonstrate the presence of a steady-state temperature gradient and indicate that localized heating via the photothermal effect within materials enables nanoscale thermal manipulations without significantly altering the bulk sample temperature in these systems. These quantitative results are further verified by reorienting nanorods within a solid polymer nanofiber without inducing any morphological changes to the highly temperature-sensitive nanofiber surface. Temperature differences of 70 – 90 °C were observed over a distances of ~100 nm. PMID:25379775

  9. Spin reorientation transition and hard magnetic properties of MnBi intermetallic compound

    NASA Astrophysics Data System (ADS)

    Suzuki, K.; Wu, X.; Ly, V.; Shoji, T.; Kato, A.; Manabe, A.

    2012-04-01

    The effects of mechanical grinding (MG) on the crystallite size, the spin reorientation transition temperature (TSR) and the hard magnetic properties in melt-spun low temperature phase (LTP) MnBi have been investigated in order to understand the origin of magnetic hardening induced by MG. The room-temperature coercive field (μ0Hcj) is enhanced dramatically from 0.08 T before MG to 1.5 T after MG for 43.2 ks while TSR is concurrently suppressed from 110 to 38 K. The coercive force exhibits positive temperature dependence approximately 50-60 K above TSR and the lowered TSR after MG could result in magnetic hardening at room temperature. The room-temperature coercive force of LTP-MnBi is highly dependent on the crystallite size (D) and is found to be described phenomenologically by the following relationship: μ0Hcj = μ0Ha(δ/D)n, where μ0Ha is ˜ 4 T, the Bloch wall width δ is 7 nm, and the exponent n is approximately 0.7. Our results suggest that the grain refinement is the primary origin of the hardening effect induced by MG with a possible minor hardening effect due to the suppression of the spin reorientation transition temperature.

  10. 3D modelling of the flow of self-compacting concrete with or without steel fibres. Part II: L-box test and the assessment of fibre reorientation during the flow

    NASA Astrophysics Data System (ADS)

    Deeb, R.; Kulasegaram, S.; Karihaloo, B. L.

    2014-12-01

    The three-dimensional Lagrangian particle-based smooth particle hydrodynamics method described in Part I of this two-part paper is used to simulate the flow of self-compacting concrete (SCC) with and without steel fibres in the L-box configuration. As in Part I, the simulation of the SCC mixes without fibres emphasises the distribution of large aggregate particles of different sizes throughout the flow, whereas the simulation of high strength SCC mixes which contain steel fibres is focused on the distribution of fibres and their orientation during the flow. The capabilities of this methodology are validated by comparing the simulation results with the L-box test carried out in the laboratory. A simple method is developed to assess the reorientation and distribution of short steel fibres in self-compacting concrete mixes during the flow. The reorientation of the fibres during the flow is used to estimate the fibre orientation factor (FOF) in a cross section perpendicular to the principal direction of flow. This estimation procedure involves the number of fibres cut by the section and their inclination to the cutting plane. This is useful to determine the FOF in practical image analysis on cut sections.

  11. Amyloplasts and Vacuolar Membrane Dynamics in the Living Graviperceptive Cell of the Arabidopsis Inflorescence StemW⃞

    PubMed Central

    Saito, Chieko; Morita, Miyo T.; Kato, Takehide; Tasaka, Masao

    2005-01-01

    We developed an adequate method for the in vivo analysis of organelle dynamics in the gravity-perceptive cell (endodermis) of the Arabidopsis thaliana inflorescence stem, revealing behavior of amyloplasts and vacuolar membranes in those cells. Amyloplasts in the endodermis showed saltatory movements even before gravistimulation by reorientation, and these movements were confirmed as microfilament dependent. From our quantitative analysis in the wild type, the gravity-oriented movement of amyloplasts mainly occurred during 0 to 3 min after gravistimulation by reorientation, supporting findings from our previous physiological study. Even after microfilament disruption, the gravity-oriented movement of amyloplasts remained. By contrast, in zig/sgr4 mutants, where a SNARE molecule functioning in vacuole biogenesis has been disrupted, the movement of amyloplasts in the endodermis is severely restricted both before and after gravistimulation by reorientation. Here, we describe vacuolar membrane behavior in these cells in the wild-type, actin filament–disrupted, and zig/sgr4 mutants and discuss its putatively important features for the perception of gravity. We also discuss the data on the two kinds of movements of amyloplasts that may play an important role in gravitropism: (1) the leading edge amyloplasts and (2) the en mass movement of amyloplasts. PMID:15689424

  12. Electric-field-induced structural changes in multilayer piezoelectric actuators during electrical and mechanical loading

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Esteves, Giovanni; Fancher, Chris M.; Röhrig, Sören

    The effects of electrical and mechanical loading on the behavior of domains and phases in Multilayer Piezoelectric Actuators (MAs) is studied using in situ high-energy X-ray diffraction (XRD) and macroscopic property measurements. Rietveld refinement is carried out on measured diffraction patterns using a two-phase tetragonal (P4mm) and rhombohedral (R3m) model. Applying an electric field promotes the rhombohedral phase, while increasing compressive uniaxial pre-stress prior to electric field application favors the tetragonal phase. The competition between electrical and mechanical energy leads to a maximal difference between electric-field-induced phase fractions at 70 MPa pre-stress. Additionally, the available volume fraction of non-180° domainmore » reorientation that can be accessed during electric field application increases with compressive pre-stress up to 70 MPa. The origin for enhanced strain and polarization with applied pre-stress is attributed to a combination of enhanced non-180° domain reorientation and electric-field-induced phase transitions. The suppression of both the electric-field-induced phase transitions and domain reorientation at high pre-stresses (>70 MPa) is attributed to a large mechanical energy barrier, and alludes to the competition of the electrical and mechanical energy within the MA during applied stimuli.« less

  13. A positively gravitropic mutant mirrors the wild-type protonemal response in the moss Ceratodon purpureus

    NASA Technical Reports Server (NTRS)

    Wagner, T. A.; Cove, D. J.; Sack, F. D.

    1997-01-01

    Wild-type Ceratodon purpureus (Hedw.) Brid. protonemata grow up in the dark by negative gravitropism. When upright wild-type protonemata are reoriented 90 degrees, they temporarily grow down soon after reorientation ("initial reversal") and also prior to cytokinesis ("mitotic reversal"). A positively gravitropic mutant designated wrong- way response (wwr-1) has been isolated by screening ultraviolet light-mutagenized Ceratodon protonemata. Protonemata of wwr-l reoriented from the vertical to the horizontal grow down with kinetics comparable to those of the wild-type. Protonemata of wwr-1 also show initial and mitotic reversals where they temporarily grow up. Thus, the direction of gravitropism, initial reversal, and mitotic reversal are coordinated though each are opposite in wwr-1 compared to the wild-type. Normal plastid zonation is still maintained in dark-grown wwr-1 apical cells, but the plastids are more numerous and plastid sedimentation is more pronounced. In addition, wwr-1 apical cells are wider and the tips greener than in the wild-type. These data suggest that a functional WWR gene product is not necessary for the establishment of some gravitropic polarity, for gravitropism, or for the coordination of the reversals. Thus, the WWR protein may normally transduce information about cell orientation.

  14. Using Neutron Diffraction to Investigate Texture Evolution During Consolidation of Deuterated Triaminotrinitrobenzene (d-TATB) Explosive Powder

    DOE PAGES

    Luscher, Darby J.; Yeager, John D.; Clausen, Bjørn; ...

    2017-05-14

    Triaminotrinitrobenzene (TATB) is a highly anisotropic molecular crystal used in several plastic-bonded explosive (PBX) formulations. A complete understanding of the orientation distribution of TATB particles throughout a PBX charge is required to understand spatially variable, anisotropic macroscale properties of the charge. Although texture of these materials can be measured after they have been subjected to mechanical or thermal loads, measuring texture evolution in situ is important in order to identify mechanisms of crystal deformation and reorientation used to better inform thermomechanical models. Neutron diffraction measurements were used to estimate crystallographic reorientation while deuterated TATB (d-TATB) powder was consolidated into amore » cylindrical pellet via a uniaxial die-pressing operation at room temperature. Both the final texture of the pressed pellet and the in situ evolution of texture during pressing were measured, showing that the d-TATB grains reorient such that (001) poles become preferentially aligned with the pressing direction. A compaction model is used to predict the evolution of texture in the pellet during the pressing process, finding that the original model overpredicted the texture strength compared to these measurements. The theory was extended to account for initial particle shape and pore space, bringing the results into good agreement with the data.« less

  15. Using Neutron Diffraction to Investigate Texture Evolution During Consolidation of Deuterated Triaminotrinitrobenzene (d-TATB) Explosive Powder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luscher, Darby J.; Yeager, John D.; Clausen, Bjørn

    Triaminotrinitrobenzene (TATB) is a highly anisotropic molecular crystal used in several plastic-bonded explosive (PBX) formulations. A complete understanding of the orientation distribution of TATB particles throughout a PBX charge is required to understand spatially variable, anisotropic macroscale properties of the charge. Although texture of these materials can be measured after they have been subjected to mechanical or thermal loads, measuring texture evolution in situ is important in order to identify mechanisms of crystal deformation and reorientation used to better inform thermomechanical models. Neutron diffraction measurements were used to estimate crystallographic reorientation while deuterated TATB (d-TATB) powder was consolidated into amore » cylindrical pellet via a uniaxial die-pressing operation at room temperature. Both the final texture of the pressed pellet and the in situ evolution of texture during pressing were measured, showing that the d-TATB grains reorient such that (001) poles become preferentially aligned with the pressing direction. A compaction model is used to predict the evolution of texture in the pellet during the pressing process, finding that the original model overpredicted the texture strength compared to these measurements. The theory was extended to account for initial particle shape and pore space, bringing the results into good agreement with the data.« less

  16. Liquid propellant reorientation in a low-gravity environment

    NASA Technical Reports Server (NTRS)

    Sumner, I. E.

    1978-01-01

    An existing empirical analysis relating to the reorientation of liquids in cylindrical tanks due to propulsive settling in a low gravity environment was extended to include the effects of geyser formation in the Weber number range from 4 to 10. Estimates of the minimum velocity increment required to be imposed on the propellant tank to achieve liquid reorientation were made. The resulting Bond numbers, based on tank radius, were found to be in the range from 3 to 5, depending upon the initial liquid fill level, with higher Bond number required for high initial fill levels. The resulting Weber numbers, based on tank radius and the velocity of the liquid leading edge, were calculated to be in the range from 6.5 to 8.5 for cylindrical tanks having a fineness ratio of 2.0, with Weber numbers of somewhat greater values for longer cylindrical tanks. It, therefore, appeared to be advantageous to allow small geysers to form and then dissipate into the surface of the collected liquid in order to achieve the minimum velocity increment. The Bond numbers which defined the separation between regions in which geyser formation did and did not occur due to propulsive settling in a spherical tank configuration ranged from 2 to 9 depending upon the liquid fill level.

  17. Electric-field-induced structural changes in multilayer piezoelectric actuators during electrical and mechanical loading

    DOE PAGES

    Esteves, Giovanni; Fancher, Chris M.; Röhrig, Sören; ...

    2017-04-08

    The effects of electrical and mechanical loading on the behavior of domains and phases in Multilayer Piezoelectric Actuators (MAs) is studied using in situ high-energy X-ray diffraction (XRD) and macroscopic property measurements. Rietveld refinement is carried out on measured diffraction patterns using a two-phase tetragonal (P4mm) and rhombohedral (R3m) model. Applying an electric field promotes the rhombohedral phase, while increasing compressive uniaxial pre-stress prior to electric field application favors the tetragonal phase. The competition between electrical and mechanical energy leads to a maximal difference between electric-field-induced phase fractions at 70 MPa pre-stress. Additionally, the available volume fraction of non-180° domainmore » reorientation that can be accessed during electric field application increases with compressive pre-stress up to 70 MPa. The origin for enhanced strain and polarization with applied pre-stress is attributed to a combination of enhanced non-180° domain reorientation and electric-field-induced phase transitions. The suppression of both the electric-field-induced phase transitions and domain reorientation at high pre-stresses (>70 MPa) is attributed to a large mechanical energy barrier, and alludes to the competition of the electrical and mechanical energy within the MA during applied stimuli.« less

  18. Towards Ultra-High Resolution Fibre Tract Mapping of the Human Brain – Registration of Polarised Light Images and Reorientation of Fibre Vectors

    PubMed Central

    Palm, Christoph; Axer, Markus; Gräßel, David; Dammers, Jürgen; Lindemeyer, Johannes; Zilles, Karl; Pietrzyk, Uwe; Amunts, Katrin

    2009-01-01

    Polarised light imaging (PLI) utilises the birefringence of the myelin sheaths in order to visualise the orientation of nerve fibres in microtome sections of adult human post-mortem brains at ultra-high spatial resolution. The preparation of post-mortem brains for PLI involves fixation, freezing and cutting into 100-μm-thick sections. Hence, geometrical distortions of histological sections are inevitable and have to be removed for 3D reconstruction and subsequent fibre tracking. We here present a processing pipeline for 3D reconstruction of these sections using PLI derived multimodal images of post-mortem brains. Blockface images of the brains were obtained during cutting; they serve as reference data for alignment and elimination of distortion artefacts. In addition to the spatial image transformation, fibre orientation vectors were reoriented using the transformation fields, which consider both affine and subsequent non-linear registration. The application of this registration and reorientation approach results in a smooth fibre vector field, which reflects brain morphology. PLI combined with 3D reconstruction and fibre tracking is a powerful tool for human brain mapping. It can also serve as an independent method for evaluating in vivo fibre tractography. PMID:20461231

  19. Rethinking the role of the rTPJ in attention and social cognition in light of the opposing domains hypothesis: findings from an ALE-based meta-analysis and resting-state functional connectivity

    PubMed Central

    Kubit, Benjamin; Jack, Anthony I.

    2013-01-01

    The right temporo-parietal junction (rTPJ) has been associated with two apparently disparate functional roles: in attention and in social cognition. According to one account, the rTPJ initiates a “circuit-breaking” signal that interrupts ongoing attentional processes, effectively reorienting attention. It is argued this primary function of the rTPJ has been extended beyond attention, through a process of evolutionarily cooption, to play a role in social cognition. We propose an alternative account, according to which the capacity for social cognition depends on a network which is both distinct from and in tension with brain areas involved in focused attention and target detection: the default mode network (DMN). Theory characterizing the rTPJ based on the area's purported role in reorienting may be falsely guided by the co-occurrence of two distinct effects in contiguous regions: activation of the supramarginal gyrus (SMG), associated with its functional role in target detection; and the transient release, during spatial reorienting, of suppression of the angular gyrus (AG) associated with focused attention. Findings based on meta-analysis and resting functional connectivity are presented which support this alternative account. We find distinct regions, possessing anti-correlated patterns of resting connectivity, associated with social reasoning (AG) and target detection (SMG) at the rTPJ. The locus for reorienting was spatially intermediate between the AG and SMG and showed a pattern of connectivity with similarities to social reasoning and target detection seeds. These findings highlight a general methodological concern for brain imaging. Given evidence that certain tasks not only activate some areas but also suppress activity in other areas, it is suggested that researchers need to distinguish two distinct putative mechanisms, either of which may produce an increase in activity in a brain area: functional engagement in the task vs. release of suppression. PMID:23847497

  20. Ultra-slow dynamics in low density amorphous ice revealed by deuteron NMR: indication of a glass transition.

    PubMed

    Löw, Florian; Amann-Winkel, Katrin; Loerting, Thomas; Fujara, Franz; Geil, Burkhard

    2013-06-21

    The postulated glass-liquid transition of low density amorphous ice (LDA) is investigated with deuteron NMR stimulated echo experiments. Such experiments give access to ultra-slow reorientations of water molecules on time scales expected for structural relaxation of glass formers close to the glass-liquid transition temperature. An involved data analysis is necessary to account for signal contributions originating from a gradual crystallization to cubic ice. Even if some ambiguities remain, our findings support the view that pressure amorphized LDA ices are of glassy nature and undergo a glass-liquid transition before crystallization.

  1. Sleep Loss, Circadian Mismatch, and Abnormalities in Reorienting of Attention in Night Workers with Shift Work Disorder

    PubMed Central

    Gumenyuk, Valentina; Howard, Ryan; Roth, Thomas; Korzyukov, Oleg; Drake, Christopher L.

    2014-01-01

    Study Objectives: Permanent night-shift workers may develop shift-work disorder (SWD). In the current study, we evaluated neurophysiological and behavioral indices of distractibility across times prior to the night shift (T1), during night hours (T2), and after acute sleep deprivation (T3) in permanent hospital night workers with and without SWD. Methods: Ten asymptomatic night workers (NW) and 18 NW with SWD participated in a 25-h sleep deprivation study. Circadian phase was evaluated by dim-light salivary melatonin onset (DLMO). Objective sleepiness was evaluated using the Multiple Sleep Latency Test (MSLT). Electrophysiological distractibility was evaluated by brain event-related potentials (ERP), whereas behavioral distractibility was evaluated by performance on a visual task in an auditory-visual distraction paradigm. Statistical analyses: Comparisons of ERP results were performed by repeated-measures analysis of variance, and t-tests were used where appropriate. A Mann-Whitney U test was used for comparison of variables (MLST, Stanford Sleepiness Scale, and DLMO) that deviated from normal. Results: First, in the SWD group, the reorienting negativity ERP amplitude was significantly attenuated compared to that in the NW group. Second, the SWD group had shorter MSLT during night shift hours (4.8 ± 4.9 min) compared to that in NW (7.8 ± 3.7 min; U = 47; z = -2.1; P < 0.03). Third, NW with SWD had a DLMO at 20:27 ± 5.0 h, whereas healthy NW had a DLMO at 05:00 ± 3.4 h (U = 43.5; z = -2.22, P < 0.03). Finally, acute sleep deprivation impaired behavioral performance and the P3a ERP in both groups. Conclusions: Our results demonstrate specific deficits in neurophysiological activity in the attentional domain among the shift-work disorder group relative to night workers. Citation: Gumenyuk V; Howard R; Roth T; Korzyukov O; Drake CL. Sleep loss, circadian mismatch, and abnormalities in reorienting of attention in night workers with shift work disorder. SLEEP 2014;37(3):545-556. PMID:24587577

  2. Temperature evolution of the local order parameter in relaxor ferroelectrics (1 - x)PMN-xPZT

    NASA Astrophysics Data System (ADS)

    Gridnev, S. A.; Glazunov, A. A.; Tsotsorin, A. N.

    2005-09-01

    The temperature dependence of the local order parameter and relaxation time distribution function have been determined in (1 - x)PMN-xPZT ceramic samples via dielectric permittivity. Above the Burns temperature, the permittivity was found to follow the Currie-Weiss law, and with temperature decreasing the deviation was observed to increase. A local order parameter was calculated from the dielectric data using a modified Landau-Devonshire approach. These results are compared to the distribution function of relaxation times. It was found that a glasslike freezing of reorientable polar clusters occurs in the temperature range of diffuse relaxor transition. The evolution of the studied system to more ordered state arises from the increased PZT content.

  3. Elastic and inelastic scattering for the 10B+58Ni system at near-barrier energies

    NASA Astrophysics Data System (ADS)

    Scarduelli, V.; Crema, E.; Guimarães, V.; Abriola, D.; Arazi, A.; de Barbará, E.; Capurro, O. A.; Cardona, M. A.; Gallardo, J.; Hojman, D.; Martí, G. V.; Pacheco, A. J.; Rodrígues, D.; Yang, Y. Y.; Deshmukh, N. N.; Paes, B.; Lubian, J.; Mendes Junior, D. R.; Morcelle, V.; Monteiro, D. S.

    2017-11-01

    Full angular distributions of the 10B elastically and inelastically scattered by 58Ni have been measured at different energies around the Coulomb barrier. The elastic and inelastic scattering of 10B on a medium mass target has been measured for the first time. The obtained angular distributions have been analyzed in terms of large-scale coupled reaction channel calculations, where several inelastic transitions of the projectile and the target, as well as the most relevant one- and two-step transfer reactions have been included in the coupling matrix. The roles of the spin reorientation, the spin-orbit interaction, and the large ground-state deformation of the 10B, in the reaction mechanism, were also investigated. The real part of the interaction potential between projectile and target was represented by a parameter-free double-folding potential, whereas no imaginary potential at the surface was considered. In this sense, the theoretical calculations were parameter free and their results were compared to experimental data to investigate the relative importance of the different reaction channels. A striking influence of the ground-state spin reorientation of the 10B nucleus was found, while all transfer reactions investigated had a minimum contribution to the dynamics of the system. Finally, the large static deformation of the 10B and the spin-orbit coupling can also play an important role in the system studied.

  4. Gelation And Mechanical Response of Patchy Rods

    NASA Astrophysics Data System (ADS)

    Kazem, Navid; Majidi, Carmel; Maloney, Craig

    We perform Brownian Dynamics simulations to study the gelation of suspensions of attractive, rod-like particles. We show that details of the particle-particle interactions can dramatically affect the dynamics of gelation and the structure and mechanics of the networks that form. If the attraction between the rods is perfectly smooth along their length, they will collapse into compact bundles. If the attraction is sufficiently corrugated or patchy, over time, a rigid space spanning network forms. We study the structure and mechanical properties of the networks that form as a function of the fraction of the surface that is allowed to bind. Surprisingly, the structural and mechanical properties are non-monotonic in the surface coverage. At low coverage, there are not a sufficient number of cross-linking sites to form networks. At high coverage, rods bundle and form disconnected clusters. At intermediate coverage, robust networks form. The elastic modulus and yield stress are both non-monotonic in the surface coverage. The stiffest and strongest networks show an essentially homogeneous deformation under strain with rods re-orienting along the extensional axis. Weaker, clumpy networks at high surface coverage exhibit relatively little re-orienting with strong non-affine deformation. These results suggest design strategies for tailoring surface interactions between rods to yield rigid networks with optimal properties. National Science Foundation and the Air Force Office of Scientific Research.

  5. Computations on metric maps in mammals: getting oriented and choosing a multi-destination route.

    PubMed

    Gallistel, C R; Cramer, A E

    1996-01-01

    The capacity to construct a cognitive map is hypothesized to rest on two foundations: (1) dead reckoning (path integration); (2) the perception of the direction and distance of terrain features relative to the animal. A map may be constructed by combining these two sources of positional information, with the result that the positions of all terrain features are represented in the coordinate framework used for dead reckoning. When animals need to become reoriented in a mapped space, results from rats and human toddlers indicate that they focus exclusively on the shape of the perceived environment, ignoring non-geometric features such as surface colors. As a result, in a rectangular space, they are misoriented half the time even when the two ends of the space differ strikingly in their appearance. In searching for a hidden object after becoming reoriented, both kinds of subjects search on the basis of the object's mapped position in the space rather than on the basis of its relationship to a goal sign (e.g. a distinctive container or nearby marker), even though they have demonstrably noted the relationship between the goal and the goal sign. When choosing a multidestination foraging route, vervet monkeys look at least three destinations ahead, even though they are only capable of keeping a maximum of six destinations in mind at once.

  6. Unilateral reorientation of microtubules at the outer epidermal wall during photo- and gravitropic curvature of maize coleoptiles and sunflower hypocotyls.

    PubMed

    Nick, P; Bergfeld, R; Schafer, E; Schopfer, P

    1990-05-01

    Auxin (indole-3-acetic acid) controls the orientation of cortical microtubes (MT) at the outer wall of the outer epidermis of growing maize coleoptiles (Bergfeld, R., Speth, V., Schopfer, P., 1988, Bot. Acta 101, 57-67). A detailed time course of MT reorientation, determined by labeling MT with fluorescent antibodies, revealed that the auxin-mediated movement of MT from the longitudinal to the transverse direction starts after less than 15 min and is completed after 60 min. This response was used for a critical test of the functional involvement of auxin in tropic curvature. It was found that phototropic (first phototropic curvature) as well as gravitropic bending are correlated with a change of MT orientation from transverse to longitudinal at the slower-growing organ flank whereas the transverse MT orientation is maintained (or even augmented) at the faster-growing organ flank. These directional changes are confined to the MT subjacent to the outer epidermal wall. The same basic results were obtained with sunflower hypocotyls subjected to phototropic or gravitropic stimulation. It is concluded that auxin is, in fact, involved in asymmetric growth leading to tropic curvature. However, our results do not allow us to discriminate between an uneven distribution of endogenous auxin or an even distribution of auxin, the activity of which is modulated by an unevenly distributed inhibitor of auxin action.

  7. Hybrid thrusters and reaction wheels strategy for large angle rapid reorientation with high precision

    NASA Astrophysics Data System (ADS)

    Ye, Dong; Sun, Zhaowei; Wu, Shunan

    2012-08-01

    The quaternion-based, high precision, large angle rapid reorientation of rigid spacecraft is the main problem investigated in this study. The operation is accomplished via a hybrid thrusters and reaction wheels strategy where thrusters are engaged in providing a primary maneuver torque in open loop, while reaction wheels provide fine control torque to achieve high precision in closed-loop control. The inaccuracy of thrusters is handled by a variable structure control (VSC). In addition, a signum function is mixed in the switching surface in VSC to produce a maneuver to the reference attitude trajectory in a shortest distance. Detailed proofs and numerical simulation examples are presented to illustrate all the technical aspects of this work.

  8. The CFVib Experiment: Control of Fluids in Microgravity with Vibrations

    NASA Astrophysics Data System (ADS)

    Fernandez, J.; Sánchez, P. Salgado; Tinao, I.; Porter, J.; Ezquerro, J. M.

    2017-10-01

    The Control of Fluids in Microgravity with Vibrations (CFVib) experiment was selected for the 2016 Fly Your Thesis! programme as part of the 65th ESA Parabolic Flight Campaign. The aim of the project is to observe the potentially complex behaviour of vibrated liquids in weightless environments and to investigate the extent to which small-amplitude vibrations can be used to influence and control this behaviour. Piezoelectric materials are used to generate high-frequency vibrations to drive surface waves and large-scale reorientation of the interface. The theory of vibroequilibria, which treats the quasi-stationary surface configurations achieved by this reorientation, was used to predict interesting parameter regimes and interpret fluid behaviour. Here we describe the scientific motivation, objectives, and design of the experiment.

  9. Effect of head group orientation on phospholipid assembly

    NASA Astrophysics Data System (ADS)

    Paul, Tanay; Saha, Jayashree

    2017-06-01

    The relationship between bilayer stability and lipid head group orientation is reported. In this work, molecular-dynamics simulations are performed to analyze the structure-property relationship of lipid biomembranes, taking into account coarse-grained model lipid interactions. The work explains the molecular scale mechanism of the phase behavior of lipid systems due to ion-lipid or anesthetic-lipid interactions, where reorientations of dipoles play a key role in modifying lipid phases and thereby alter biomembrane function. Our study demonstrates that simple dipolar reorientation is indeed sufficient in tuning a bilayer to a randomly flipped nonbilayer lamellar phase. This study may be used to assess the impact of changes in lipid phase characteristics on biomembrane structure due to the presence of anesthetics and ions.

  10. Velocity changes, long runs, and reversals in the Chromatium minus swimming response.

    PubMed Central

    Mitchell, J G; Martinez-Alonso, M; Lalucat, J; Esteve, I; Brown, S

    1991-01-01

    The velocity, run time, path curvature, and reorientation angle of Chromatium minus were measured as a function of light intensity, temperature, viscosity, osmotic pressure, and hydrogen sulfide concentration. C. minus changed both velocity and run time. Velocity decreased with increasing light intensity in sulfide-depleted cultures and increased in sulfide-replete cultures. The addition of sulfide to cultures grown at low light intensity (10 microeinsteins m-2 s-1) caused mean run times to increase from 10.5 to 20.6 s. The addition of sulfide to cultures grown at high light intensity (100 microeinsteins m-2 s-1) caused mean run times to decrease from 15.3 to 7.7 s. These changes were maintained for up to an hour and indicate that at least some members of the family Chromatiaceae simultaneously modulate velocity and turning frequency for extended periods as part of normal taxis. Images PMID:1991736

  11. Real-time maneuver optimization of space-based robots in a dynamic environment: Theory and on-orbit experiments

    NASA Astrophysics Data System (ADS)

    Chamitoff, Gregory E.; Saenz-Otero, Alvar; Katz, Jacob G.; Ulrich, Steve; Morrell, Benjamin J.; Gibbens, Peter W.

    2018-01-01

    This paper presents the development of a real-time path-planning optimization approach to controlling the motion of space-based robots. The algorithm is capable of planning three dimensional trajectories for a robot to navigate within complex surroundings that include numerous static and dynamic obstacles, path constraints and performance limitations. The methodology employs a unique transformation that enables rapid generation of feasible solutions for complex geometries, making it suitable for application to real-time operations and dynamic environments. This strategy was implemented on the Synchronized Position Hold Engage Reorient Experimental Satellite (SPHERES) test-bed on the International Space Station (ISS), and experimental testing was conducted onboard the ISS during Expedition 17 by the first author. Lessons learned from the on-orbit tests were used to further refine the algorithm for future implementations.

  12. The structure and dynamics of rat apo-cellular retinol-binding protein II in solution: comparison with the X-ray structure.

    PubMed

    Lu, J; Lin, C L; Tang, C; Ponder, J W; Kao, J L; Cistola, D P; Li, E

    1999-03-05

    The structure and dynamics of rat apo-cellular retinol binding protein II (apo-CRBP II) in solution has been determined by multidimensional NMR analysis of uniformly enriched recombinant rat 13C, 15N-apo-CRBP II and 15N-apo-CRBP II. The final ensemble of 24 NMR structures has been calculated from 3274 conformational restraints or 24.4 restraints/residue. The average root-mean-square deviation of the backbone atoms for the final 24 structures relative to their mean structure is 1.06 A. Although the average solution structure is very similar to the crystal structure, it differs at the putative entrance to the binding cavity, which is formed by the helix-turn-helix motif, the betaC-betaD turn and the betaE-betaF turn. The mean coordinates of the main-chain atoms of amino acid residues 28-38 are displaced in the solution structure relative to the crystal structure. The side-chain of F58, located on the betaC-betaD turn, is reoriented such that it interacts with L37 and no longer blocks entry into the ligand-binding pocket. Residues 28-35, which form the second helix of the helix-turn-helix motif in the crystal structure, do not exhibit a helical conformation in the solution structure. The solution structure of apo-CRBP II exhibits discrete regions of backbone disorder which are most pronounced at residues 28-32, 37-38 and 73-76 in the betaE-betaF turn as evaluated by the consensus chemical shift index, the root-mean-square deviation, amide 1H exchange rates and 15N relaxation studies. These studies indicate that fluctuations in protein conformation occur on the microseconds to ms time-scale in these regions of the protein. Some of these exchange processes can be directly observed in the three-dimensional 15N-resolved NOESY spectrum. These results suggest that in solution, apo-CRBP II undergoes conformational changes on the microseconds to ms time-scale which result in increased access to the binding cavity. Copyright 1999 Academic Press.

  13. 360° deterministic magnetization rotation in a three-ellipse magnetoelectric heterostructure

    NASA Astrophysics Data System (ADS)

    Kundu, Auni A.; Chavez, Andres C.; Keller, Scott M.; Carman, Gregory P.; Lynch, Christopher S.

    2018-03-01

    A magnetic dipole-coupled magnetoelectric heterostructure comprised of three closely spaced ellipse shapes was designed and shown to be capable of achieving deterministic in-plane magnetization rotation. The design approach used a combination of conventional micromagnetic simulations to obtain preliminary configurations followed by simulations using a fully strain-coupled, time domain micromagnetic code for a detailed assessment of performance. The conventional micromagnetic code has short run times and was used to refine the ellipse shape and orientation, but it does not accurately capture the effects of the strain gradients present in the piezoelectric and magnetostrictive layers that contribute to magnetization reorientation. The fully coupled code was used to assess the effects of strain and magnetic field gradients on precessional switching in the side ellipses and on the resulting dipole-field driven magnetization reorientation in the center ellipse. The work led to a geometry with a CoFeB ellipse (125 nm × 95 nm × 4 nm) positioned between two smaller CoFeB ellipses (75 nm × 50 nm × 4 nm) on a 500 nm PZT-5H film substrate clamped at its bottom surface. The smaller ellipses were oriented at 45° and positioned at 70° and 250° about the central ellipse due to the film deposition on a thick substrate. A 7.3 V pulse applied to the PZT for 0.22 ns produced 180° switching of the magnetization in the outer ellipses that then drove switching in the center ellipse through dipole-dipole coupling. Full 360° deterministic rotation was achieved with a second pulse. The temporal response of the resulting design is discussed.

  14. Change of focus: from intensive care towards organ donation.

    PubMed

    Meyer, Käthe; Bjørk, Ida T

    2008-02-01

    To progress from identifying a potential organ donor to implementing the actual organ donation effectively is a challenging process for all involved. The nurses might find the change of focus difficult, as the donor organ acquisition process often starts before the relatives had been informed and have had the time to reorient themselves about the severe situation of the patient and have been briefed on the option of organ donation. The purpose was to investigate the hospital-based education in organ donation at the 28 Norwegian donor hospitals, and elicit the needs of the intensive care nurses for imparting of required knowledge and support in shifting their focus from intensive care towards the process of organ procurement. Hospital-based education and guidelines in organ donation were analyzed by scrutinizing the documents available. Eleven units were found to have their own guidelines and only three hospitals had organ donation in their educational programme. Intensive care nurses at three hospitals participated in focus groups. The main finding was the need for collaboration and mutual understanding within the treatment team. Nurses expounded the multiple responsibilities that they discharged during the course of intensive care. In reorienting their focus from intensive care to donor organ procurement, the time of death was explained as the crucial turning point. The knowledge of intensive care staff and professional competence were crucial in winning the relatives' trust and were central in the communication processes. Donor hospitals should implement systematic training and debriefing, where both nurses and physicians contribute to this process. Well-prepared protocols for organ donation at hospitals can define responsibilities assigned to different members of the donor organ acquisition team.

  15. Age-related modifications in steering behaviour: effects of base-of-support constraints at the turn point.

    PubMed

    Paquette, Maxime R; Fuller, Jason R; Adkin, Allan L; Vallis, Lori Ann

    2008-09-01

    This study investigated the effects of altering the base of support (BOS) at the turn point on anticipatory locomotor adjustments during voluntary changes in travel direction in healthy young and older adults. Participants were required to walk at their preferred pace along a 3-m straight travel path and continue to walk straight ahead or turn 40 degrees to the left or right for an additional 2-m. The starting foot and occasionally the gait starting point were adjusted so that participants had to execute the turn using a cross-over step with a narrow BOS or a lead-out step with a wide BOS. Spatial and temporal gait variables, magnitudes of angular segmental movement, and timing and sequencing of body segment reorientation were similar despite executing the turn with a narrow or wide BOS. A narrow BOS during turning generated an increased step width in the step prior to the turn for both young and older adults. Age-related changes when turning included reduced step velocity and step length for older compared to young adults. Age-related changes in the timing and sequencing of body segment reorientation prior to the turn point were also observed. A reduction in walking speed and an increase in step width just prior to the turn, combined with a delay in motion of the center of mass suggests that older adults used a more cautious combined foot placement and hip strategy to execute changes in travel direction compared to young adults. The results of this study provide insight into mobility constraints during a common locomotor task in older adults.

  16. Face specificity and the role of metal adatoms in molecular reorientation at surfaces

    NASA Astrophysics Data System (ADS)

    Perry, C. C.; Haq, S.; Frederick, B. G.; Richardson, N. V.

    1998-07-01

    Using reflection absorption infrared spectroscopy (RAIRS), the coverage-dependent reorientation of the benzoate species on the (110) and (111) faces of copper is compared and contrasted. Whereas on Cu(110) benzoate reorients from a flat-lying to an upright orientation with increasing coverage, on Cu(111), at all coverages, benzoate is aligned normal to the surface. The formation of periodic, flat-lying copper-benzoate structures has been attributed to the availability of metal adatoms, which differs dramatically between the (111) and (110) faces. We discuss the face specificity of molecular orientation by comparing calculated formation energies of adatom vacancies from ledges and kink sites on (100), (110) and (111) faces. Further support for this model is given by the evaporation of sodium, either by pre- or post-dosing, onto low-coverage benzoate/Cu(111), which induces benzoate to convert from a perpendicular to a parallel orientation. Likewise, coevaporation of Cu while dosing benzoic acid onto the Cu(111) surface also results in a majority of flat-lying benzoate species. Finally, for adsorption on the p(2×1)O/Cu(110) reconstruction, benzoate occurs only as the upright species, which is consistent with reducing the copper mobility and availability on the (110) face. We therefore suggest the possible role of metal adatoms as a new mechanism in controlling adsorbate orientation and therefore face specificity in surface reactions.

  17. Topographical Organization of Attentional, Social, and Memory Processes in the Human Temporoparietal Cortex123

    PubMed Central

    Webb, Taylor W.; Kelly, Yin T.; Graziano, Michael S. A.

    2016-01-01

    Abstract The temporoparietal junction (TPJ) is activated in association with a large range of functions, including social cognition, episodic memory retrieval, and attentional reorienting. An ongoing debate is whether the TPJ performs an overarching, domain-general computation, or whether functions reside in domain-specific subdivisions. We scanned subjects with fMRI during five tasks known to activate the TPJ, probing social, attentional, and memory functions, and used data-driven parcellation (independent component analysis) to isolate task-related functional processes in the bilateral TPJ. We found that one dorsal component in the right TPJ, which was connected with the frontoparietal control network, was activated in all of the tasks. Other TPJ subregions were specific for attentional reorienting, oddball target detection, or social attribution of belief. The TPJ components that participated in attentional reorienting and oddball target detection appeared spatially separated, but both were connected with the ventral attention network. The TPJ component that participated in the theory-of-mind task was part of the default-mode network. Further, we found that the BOLD response in the domain-general dorsal component had a longer latency than responses in the domain-specific components, suggesting an involvement in distinct, perhaps postperceptual, computations. These findings suggest that the TPJ performs both domain-general and domain-specific computations that reside within spatially distinct functional components. PMID:27280153

  18. Indonesia Country Analysis Brief

    EIA Publications

    2015-01-01

    Indonesia is reorienting energy production from serving primarily export markets to meeting its growing domestic consumption. Indonesia's energy industry has faced challenges in recent years from regulatory uncertainty and inadequate investment.

  19. A feasibility study of a new method for electrically producing seizures in man: focal electrically administered seizure therapy [FEAST].

    PubMed

    Nahas, Ziad; Short, Baron; Burns, Carol; Archer, Melanie; Schmidt, Matthew; Prudic, Joan; Nobler, Mitchell S; Devanand, D P; Fitzsimons, Linda; Lisanby, Sarah H; Payne, Nancy; Perera, Tarique; George, Mark S; Sackeim, Harold A

    2013-05-01

    Electroconvulsive therapy (ECT) remains the most effective acute treatment for severe major depression, but with significant risk of adverse cognitive effects. Unidirectional electrical stimulation with a novel electrode placement and geometry (Focal Electrically Administered Seizure Therapy (FEAST)) has been proposed as a means to initiate seizures in prefrontal cortex prior to secondary generalization. As such, it may have fewer cognitive side effects than traditional ECT. We report on its first human clinical application. Seventeen unmedicated depressed adults (5 men; 3 bipolar disorder; age 53 ± 16 years) were recruited after being referred for ECT. Open-label FEAST was administered with a modified spECTrum 5000Q device and a traditional ECT dosing regimen until patients clinically responded. Clinical and cognitive assessments were obtained at baseline, and end of course. Time to orientation recovery, a predictor of long-term amnestic effects, was assessed at each treatment. Nonresponders to FEAST were transitioned to conventional ECT. One patient withdrew from the study after a single titration session. After the course of FEAST (median 10 sessions), there was a 46.1 ± 35.5% improvement in Hamilton Rating Scale for Depression (HRSD24) scores compared to baseline (33.1 ± 6.8, 16.8 ± 10.9; P < 0.0001). Eight of 16 patients met response criteria (50% decrease in HRSD24) and 5/16 met remission criteria (HRSD24 ≤ 10). Patients achieved full re-orientation (4 of 5 items) in 5.5 ± 6.4 min (median = 3.6), timed from when their eyes first opened after treatment. In this feasibility study, FEAST produced clinically meaningful antidepressant improvement, with relatively short time to reorientation. Our preliminary work first in primates and now depressed adults demonstrates that FEAST is feasible, safe, well-tolerated and, if efficacy can be optimized, has potential to replace traditional ECT. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Domain-general neural correlates of dependency formation: Using complex tones to simulate language.

    PubMed

    Brilmayer, Ingmar; Sassenhagen, Jona; Bornkessel-Schlesewsky, Ina; Schlesewsky, Matthias

    2017-08-01

    There is an ongoing debate whether the P600 event-related potential component following syntactic anomalies reflects syntactic processes per se, or if it is an instance of the P300, a domain-general ERP component associated with attention and cognitive reorientation. A direct comparison of both components is challenging because of the huge discrepancy in experimental designs and stimulus choice between language and 'classic' P300 experiments. In the present study, we develop a new approach to mimic the interplay of sequential position as well as categorical and relational information in natural language syntax (word category and agreement) in a non-linguistic target detection paradigm using musical instruments. Participants were instructed to (covertly) detect target tones which were defined by instrument change and pitch rise between subsequent tones at the last two positions of four-tone sequences. We analysed the EEG using event-related averaging and time-frequency decomposition. Our results show striking similarities to results obtained from linguistic experiments. We found a P300 that showed sensitivity to sequential position and a late positivity sensitive to stimulus type and position. A time-frequency decomposition revealed significant effects of sequential position on the theta band and a significant influence of stimulus type on the delta band. Our results suggest that the detection of non-linguistic targets defined via complex feature conjunctions in the present study and the detection of syntactic anomalies share the same underlying processes: attentional shift and memory based matching processes that act upon multi-feature conjunctions. We discuss the results as supporting domain-general accounts of the P600 during natural language comprehension. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Commentary: Reconsidering the Role of Context in Diabetes Prevention

    PubMed Central

    Mezuk, Briana; Concha, Jeannie B.; Perrin, Paul; Green, Tiffany

    2017-01-01

    A substantial gap remains between what we know about type 2 diabetes prevention and our ability to apply that knowledge in socially disadvantaged populations at highest risk. This gap results, in part, from a lack of integration between epidemiologic science and social psychology theory, particularly regarding the intersections of stress, self-regulatory health behaviors, and the biological mechanisms underlying the development of diabetes. In this commentary, we describe the utility of a theoretical framework that focuses on the intersection of biological, psychosocial, and environmental contexts as they apply to diabetes disparities, and how such a framework could inform a translational research agenda to reorient prevention efforts to address these inequalities. Such reorientation is needed to ensure that the implementation of prevention efforts does not inadvertently widen diabetes disparities. PMID:28115823

  2. Nematicons and Their Electro-Optic Control: Light Localization and Signal Readdressing via Reorientation in Liquid Crystals

    PubMed Central

    Piccardi, Armando; Alberucci, Alessandro; Assanto, Gaetano

    2013-01-01

    Liquid crystals in the nematic phase exhibit substantial reorientation when the molecules are driven by electric fields of any frequencies. Exploiting such a response at optical frequencies, self-focusing supports transverse localization of light and the propagation of self-confined beams and waveguides, namely “nematicons”. Nematicons can guide other light signals and interact with inhomogeneities and other beams. Moreover, they can be effectively deviated by using the electro-optic response of the medium, leading to several strategies for voltage-controlled reconfiguration of light-induced guided-wave circuits and signal readdressing. Hereby, we outline the main features of nematicons and review the outstanding progress achieved in the last twelve years on beam self-trapping and electro-optic readdressing. PMID:24108367

  3. Tidal reorientation and the fracturing of Jupiter's moon Europa

    NASA Technical Reports Server (NTRS)

    Mcewen, A. S.

    1986-01-01

    The lineaments on Europa are discussed in terms of the orientation of the lineaments relative to the tensile stress trajectories due to tidal distortions and to nonsynchronous rotation. The cracks are noticeable by their darker albedo compared to the presumed water ice surrounding them. The stress trajectories for tidal distortion of a thin elastic shell are superimposed on Mercator projection maps of the lineaments. It is shown that the lineaments are mainly oriented at high angles to the tensile stress trajectories that would be expected for regularly occurring nonsynchronous rotation, i.e., extensional fractures would appear. The reorientation motions which would cause the fractures are estimated. It is suggested that the fractures occur episodically to release stresses built up on the tensile surface of the crust during the continuous nonsynchronous rotation of Europa.

  4. Experimental study of transient liquid motion in orbiting spacecraft

    NASA Technical Reports Server (NTRS)

    Berry, R. L.; Tegart, J. R.

    1975-01-01

    The results are presented of a twofold study of transient liquid motion such as that which will be experienced during orbital maneuvers by space tug. A test program was conducted in a low-g test facility involving twenty-two drops. Biaxial, low-g accelerations were applied to an instrumented, model propellant tank during free-fall testing, and forces exerted during liquid reorientation were measured and recorded. Photographic records of the liquid reorientation were also made. The test data were used to verify a mechanical analog which portrays the liquid as a point mass moving on an ellipsoidal constraint surface. The mechanical analog was coded into a FORTRAN IV digital computer program: LAMPS, Large AMPlitude Slosh. Test/analytical correlation indicates that the mechanical analog is capable of predicting the overall force trends measured during testing.

  5. Distribution of self-propelled organisms in fluid flows

    NASA Astrophysics Data System (ADS)

    Neufeld, Zoltan

    2006-11-01

    We study the distribution of microorganisms represented as self-propelled particles in a moving fluid medium. The particles are advected by the flow and, in addition, they swim in a direction controlled by external factors. Two cases are considered: 1. passive spheroidal particles, that swim with constant speed but the swimming direction is reoriented by the viscous torque acting on the spheroid due to the local velocity field, and 2. chemotactic particles, whose swimming speed is oriented and proportional to the gradient of the concentration of a chemoattractant. We show that the combined effects of chaotic mixing and chemotaxis or flow reorientation leads to aggregation of the particles along a complex manifold. We analyse the properties of the aggregates and the efficiency of chemotaxis in flows with strongly non-uniform fluctuating distribution of the chemottractant.

  6. Stereological analysis of gravitropism in protonemata of the moss Ceratodon

    NASA Technical Reports Server (NTRS)

    Walker, L. M.; Sack, F. D.

    1997-01-01

    Apical cells of dark-grown protonemata of the moss Cerotodon purpureus are negatively gravitropic. Previous light microscopy has shown that reorientation to the horizontal induces amyloplast sedimentation and redistribution of microtubules. To determine whether other components become redistributed laterally or axially, the apical 35 micrometers of both vertical and horizontal apical cells were compared stereologically using transmission electron microscopy. Reorientation to the horizontal changed the longitudinal distributions of tubular ER, Golgi stacks, and vesicles but not cisternal ER, mitochondria, and plastids. Only plastids showed a statistically significant lateral redistribution after horizontal placement. Qualitative examination of the sedimentation zone showed plastids sedimented close to peripherally located ER with vacuoles displaced above plastids. These results argue against a model where differential tip growth results from a redistribution of Golgi stacks or exocytic vesicles.

  7. Guarding against emerging epidemics: addressing HIV and AIDS among culturally and linguistically diverse communities in NSW.

    PubMed

    McMahon, Tadgh; Moreton, Renee J; Luisi, Barbara N

    2010-01-01

    In Australia, people from culturally and linguistically diverse backgrounds, largely born in low- and middle-income countries, accounted for 24% of HIV notifications in the period 2004-2008. NSW has one of the most culturally diverse communities in Australia and is also the most popular destination for both permanent and temporary migrants. Consequently people from culturally and linguistically diverse backgrounds have recently been recognised as a priority in the NSW HIV/AIDS Strategy. The National Health and Medical Research Council provides a cultural competency framework for re-orienting public health and health promotion programs to better meet the needs of these communities. It is being applied to re-orientate the HIV response in NSW. Examples of how this framework can be implemented are provided.

  8. Reverse Launch Abort System Parachute Architecture Trade Study

    NASA Technical Reports Server (NTRS)

    Litton, Daniel K.; O'Keefe, Stephen A.; Winski, Richard G.

    2011-01-01

    This study investigated a potential Launch Abort System (LAS) Concept of Operations and abort parachute architecture. The purpose of the study was to look at the concept of jettisoning the LAS tower forward (Reverse LAS or RLAS) into the free-stream flow rather than after reorienting to a heatshield forward orientation. A hypothesized benefit was that due to the compressed timeline the dynamic pressure at main line stretch would be substantially less. This would enable the entry parachutes to be designed and sized based on entry loading conditions rather than the current stressing case of a Pad Abort. Ultimately, concerns about the highly dynamic reorientation of the CM via parachutes, and the additional requirement of a triple bridle attachment for the RLAS parachute system, overshadowed the potential benefits and ended this effort.

  9. SOCIAL AND NON-SOCIAL CUEING OF VISUOSPATIAL ATTENTION IN AUTISM AND TYPICAL DEVELOPMENT

    PubMed Central

    Pruett, John R.; LaMacchia, Angela; Hoertel, Sarah; Squire, Emma; McVey, Kelly; Todd, Richard D.; Constantino, John N.; Petersen, Steven E.

    2013-01-01

    Three experiments explored attention to eye gaze, which is incompletely understood in typical development and is hypothesized to be disrupted in autism. Experiment 1 (n=26 typical adults) involved covert orienting to box, arrow, and gaze cues at two probabilities and cue-target times to test whether reorienting for gaze is endogenous, exogenous, or unique; experiment 2 (total n=80: male and female children and adults) studied age and sex effects on gaze cueing. Gaze cueing appears endogenous and may strengthen in typical development. Experiment 3 tested exogenous, endogenous, and/or gaze-based orienting in 25 typical and 27 Autistic Spectrum Disorder (ASD) children. ASD children made more saccades, slowing their reaction times; however, exogenous and endogenous orienting, including gaze cueing, appear intact in ASD. PMID:20809377

  10. Coronal Mass Ejection early-warning mission by solar-photon sailcraft

    NASA Astrophysics Data System (ADS)

    Vulpetti, Giovanni; Circi, Christian; Pino, Tommaso

    2017-11-01

    A preliminary investigation of the early warning of solar storms caused by Coronal Mass Ejection has been carried out. A long warning time could be obtained with a sailcraft synchronous with the Earth-Moon barycenter, and stationed well below the L1 point. In this paper, the theory of heliocentric synchronous sailcraft is set up, its perturbed orbit is analyzed, and a potential solution capable of providing an annual synchrony is carried out. A simple analysis of the response from a low-mass electrochromic actuator for the realization of station-keeping attitude maneuvers is put forwards, and an example of propellantless re-orientation maneuver is studied.

  11. Microstructural Modeling of Dynamic Intergranular and Transgranular Fracture Modes in Zircaloys

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohammed, I.; Zikry, M.A.; Ziaei, S.

    2017-04-01

    In this time period, we have continued to focus on (i) refining the thermo-mechanical fracture model for zirconium (Zr) alloys subjected to large deformations and high temperatures that accounts for the cracking of ZrH and ZrH2 hydrides, (ii) formulating a framework to account intergranular fracture due to iodine diffusion and pit formation in grain-boundaries (GBs). Our future objectives are focused on extending to a combined population of ZrH and ZrH2 populations and understanding how thermo-mechanical behavior affects hydride reorientation and cracking. We will also refine the intergranular failure mechanisms for grain boundaries with pits.

  12. Zero Robotics at Kennedy Space Center Visitor Complex

    NASA Image and Video Library

    2017-08-11

    A trio of programmable off-the-shelf Sphero robots are shown at the Center for Space Education at NASA's Kennedy Space Center in Florida. The Spheros were available for students to practice their programming skills during "loss of signal" times when the connection to the International Space Station was temporarily unavailable. Teams from across the state of Florida were gathered at Kennedy for the finals of the Zero Robotics Middle School Summer Program national championship. The five-week program allows rising sixth- through ninth-graders to write programs for small satellites called SPHERES (Synchronized, Position, Hold, Engage, Reorient, Experimental Satellites). Finalists saw their code tested aboard the orbiting laboratory.

  13. The hydration structure of the heavy-alkalines Rb+ and Cs+ through molecular dynamics and X-ray absorption spectroscopy: surface clusters and eccentricity.

    PubMed

    Caralampio, Daniel Z; Martínez, José M; Pappalardo, Rafael R; Marcos, Enrique Sánchez

    2017-11-01

    Physicochemical properties of the two heaviest stable alkaline cations, Rb + and Cs + , in water have been examined from classical molecular dynamics (MD) simulations. Alkaline cation-water intermolecular potentials have been built from ab initio interaction energies of [M(H 2 O) n ] + clusters. Unlike in the case of other monatomic metal cations, the sampling needed the inclusion of surface clusters to properly describe the interactions. The first coordination shell is found at an average M-O distance of 2.87 Å and 3.12 Å for Rb + and Cs + , respectively, with coordination numbers of 8 and 10. Structural, dynamical and energetic properties are discussed on the basis of the delicate compromise among the ion-water and water-water interactions which contribute almost on the same foot to the definition of the solvent structure around the ions. A significant asymmetry is detected in the Rb + and Cs + first hydration shell. Reorientational times of first-shell water molecules for Cs + support a clear structure-breaking nature for this cation, whereas the Rb + values do not differ from pure water behavior. Experimental EXAFS and XANES spectra have been compared to simulated ones, obtained by means of application of the FEFF code to a set of statistically significant structures taken from the MD simulations. Due to the presence of multi-excitations in the absorption spectra, theoretical-experimental agreement for the EXAFS spectra is reached when the multi-excitations are removed from the experimental spectra.

  14. Experimental and numerical investigations of resonant acoustic waves in near-critical carbon dioxide.

    PubMed

    Hasan, Nusair; Farouk, Bakhtier

    2015-10-01

    Flow and transport induced by resonant acoustic waves in a near-critical fluid filled cylindrical enclosure is investigated both experimentally and numerically. Supercritical carbon dioxide (near the critical or the pseudo-critical states) in a confined resonator is subjected to acoustic field created by an electro-mechanical acoustic transducer and the induced pressure waves are measured by a fast response pressure field microphone. The frequency of the acoustic transducer is chosen such that the lowest acoustic mode propagates along the enclosure. For numerical simulations, a real-fluid computational fluid dynamics model representing the thermo-physical and transport properties of the supercritical fluid is considered. The simulated acoustic field in the resonator is compared with measurements. The formation of acoustic streaming structures in the highly compressible medium is revealed by time-averaging the numerical solutions over a given period. Due to diverging thermo-physical properties of supercritical fluid near the critical point, large scale oscillations are generated even for small sound field intensity. The strength of the acoustic wave field is found to be in direct relation with the thermodynamic state of the fluid. The effects of near-critical property variations and the operating pressure on the formation process of the streaming structures are also investigated. Irregular streaming patterns with significantly higher streaming velocities are observed for near-pseudo-critical states at operating pressures close to the critical pressure. However, these structures quickly re-orient to the typical Rayleigh streaming patterns with the increase operating pressure.

  15. Formation and field-driven dynamics of nematic spheroids.

    PubMed

    Fu, Fred; Abukhdeir, Nasser Mohieddin

    2017-07-19

    Unlike the canonical application of liquid crystals (LCs), LC displays, emerging technologies based on LC materials are increasingly leveraging the presence of nanoscale defects. The inherent nanoscale characteristics of LC defects present both significant opportunities as well as barriers for the application of this fascinating class of materials. Simulation-based approaches to the study of the effects of confinement and interface anchoring conditions on LC domains has resulted in significant progress over the past decade, where simulations are now able to access experimentally-relevant length scales while simultaneously capturing nanoscale defect structures. In this work, continuum simulations were performed in order to study the dynamics of micron-scale nematic LC spheroids of varying shape. Nematic spheroids are one of the simplest inherently defect-containing LC structures and are relevant to polymer-dispersed LC-based "smart" window technology. Simulation results include nematic phase formation and external field-switching dynamics of nematic spheroids ranging in shape from oblate to prolate. Results include both qualitative and quantitative insight into the complex coupling of nanoscale defect dynamics and structure transitions to micron-scale reorientation. Dynamic mechanisms are presented and related to structural transitions in LC defects present in the nematic domain. Domain-averaged metrics including order parameters and response times are determined for a range of experimentally-accessible electric field strengths. These results have both fundamental and technological relevance, in that increased understanding of LC dynamics in the presence of defects is a key barrier to continued advancement in the field.

  16. Dynamic evolution of light-induced orientation of dye-doped liquid crystals in liquid phase studied by time-resolved optically heterodyned optical Kerr effect technique.

    PubMed

    Yang, Pei; Liu, Liying; Xu, Lei

    2008-02-28

    Transient evolution of light-induced molecular reorientation both in 1-amino-anthraquinone (1AAQ) dye and azobenzene doped isotropic liquid crystals (LCs) were studied by time-resolved optically heterodyned optical Kerr effect method. The results give clear direct experimental proof that under short pulse (30 ps) excitation, LC molecules orientate toward the excitation light polarization direction in the 1AAQ/LC system. However, LC molecular orientation becomes orthogonal to the light polarization in azobenzene/LC system. Time-resolved excited-state absorption of 1AAQ and wavelength dependent excited-state absorption of azobenzene were also observed and their contributions to the early dynamics of the third order optical responses of the two systems were confirmed. A simplified two-level mean-field theory was derived to reveal the intensity dependence of orientation enhancement factor in azobenzene/LC system considering the photoisomerization process.

  17. Tracker implementation for the orbiter Ku-band communications antenna

    NASA Technical Reports Server (NTRS)

    Rudnicki, J. F.; Lindsey, J. F.

    1976-01-01

    Possible implementations and recommendations for the Space Shuttle Ku-Band integrated communications/radar antenna tracking system were evaluated. Communication aspects involving the Tracking Data Relay Satellite (TDRS)/Orbiter Ku-Band link are emphasized. Detailed analysis of antenna sizes, gains and signal-to-noise ratios shows the desirability of using maximum size 36-inch diameter dish and a triple channel monopulse. The use of the original baselined 20 inch dish is found to result in excessive acquisition time since the despread signal would be used in the tracking loop. An evaluation of scan procedures which includes vehicle dynamics, designation error, time for acquisition and probability of acquisition shows that the conical scan is preferred since the time for lock-on for relatively slow look angle rates will be significantly shorter than the raster scan. Significant improvement in spherical coverage may be obtained by reorienting the antenna gimbal to obtain maximum blockage overlap.

  18. Slip re-orientation in the oblique Abiquiu embayment, northern Rio Grande rift

    NASA Astrophysics Data System (ADS)

    Liu, Y.; Murphy, M. A.; Andrea, R. A.

    2015-12-01

    Traditional models of oblique rifting predict that an oblique fault accommodates both dip-slip and strike-slip kinematics. However, recent analog experiments suggest that slip can be re-oriented to almost pure dip-slip on oblique faults if a preexisting weak zone is present at the onset of oblique extension. In this study, we use fault slip data from the Abiquiu embayment in northern Rio Grande rift to test the new model. The Rio Grande rift is a Cenozoic oblique rift extending from southern Colorado to New Mexico. From north to south, it comprises three major half grabens (San Luis, Española, and Albuquerque). The Abiquiu embayment is a sub-basin of the San Luis basin in northern New Mexico. Rift-border faults are generally older and oblique to the trend of the rift, whereas internal faults are younger and approximately N-S striking, i.e. orthogonal to the regional extension direction. Rift-border faults are deep-seated in the basement rocks while the internal faults only cut shallow stratigraphic sections. It has been suggested by many that inherited structures may influence the Rio Grande rifting. Particularly, Laramide structures (and possibly the Ancestral Rockies as well) that bound the Abiquiu embayment strike N- to NW. Our data show that internal faults in the Abiquiu embayment exhibit almost pure dip-slip (rake of slickenlines = 90º ± 15º), independent of their orientations with respect to the regional extension direction. On the contrary, border faults show two sets of rakes: almost pure dip-slip (rake = 90º ± 15º) where the fault is sub-parallel to the foliation, and moderately-oblique (rake = 30º ± 15º) where the fault is high angle to the foliation. We conclude that slip re-orientation occurs on most internal faults and some oblique border faults under the influence of inherited structures. Regarding those border faults on which slip is not re-oriented, we hypothesize that it may be caused by the Jemez volcanism or small-scale mantle convection.

  19. Exogenous (automatic) attention to emotional stimuli: a review.

    PubMed

    Carretié, Luis

    2014-12-01

    Current knowledge on the architecture of exogenous attention (also called automatic, bottom-up, or stimulus-driven attention, among other terms) has been mainly obtained from studies employing neutral, anodyne stimuli. Since, from an evolutionary perspective, exogenous attention can be understood as an adaptive tool for rapidly detecting salient events, reorienting processing resources to them, and enhancing processing mechanisms, emotional events (which are, by definition, salient for the individual) would seem crucial to a comprehensive understanding of this process. This review, focusing on the visual modality, describes 55 experiments in which both emotional and neutral irrelevant distractors are presented at the same time as ongoing task targets. Qualitative and, when possible, meta-analytic descriptions of results are provided. The most conspicuous result is that, as confirmed by behavioral and/or neural indices, emotional distractors capture exogenous attention to a significantly greater extent than do neutral distractors. The modulatory effects of the nature of distractors capturing attention, of the ongoing task characteristics, and of individual differences, previously proposed as mediating factors, are also described. Additionally, studies reviewed here provide temporal and spatial information-partially absent in traditional cognitive models-on the neural basis of preattention/evaluation, reorienting, and sensory amplification, the main subprocesses involved in exogenous attention. A model integrating these different levels of information is proposed. The present review, which reveals that there are several key issues for which experimental data are surprisingly scarce, confirms the relevance of including emotional distractors in studies on exogenous attention.

  20. Transcriptional and computational study of expansins differentially expressed in response to inclination in radiata pine.

    PubMed

    Mateluna, Patricio; Valenzuela-Riffo, Felipe; Morales-Quintana, Luis; Herrera, Raúl; Ramos, Patricio

    2017-06-01

    Plants have the ability to reorient their vertical growth when exposed to inclination. This response can be as quick as 2 h in inclined young pine (Pinus radiata D. Don) seedlings, with over accumulation of lignin observed after 9 days s. Several studies have identified expansins involved in cell expansion among other developmental processes in plants. Six putative expansin genes were identified in cDNA libraries isolated from inclined pine stems. A differential transcript abundance was observed by qPCR analysis over a time course of inclination. Five genes changed their transcript accumulation in both stem sides in a spatial and temporal manner compared with non-inclined stem. To compare these expansin genes, and to suggest a possible mechanism of action at molecular level, the structures of the predicted proteins were built by comparative modeling methodology. An open groove on the surface of the proteins composed of conserved zresidues was observed. Using a cellulose polymer as ligand the protein-ligand interaction was evaluated, with the results showing differences in the protein-ligand interaction mode. Differences in the binding energy interaction can be explained by changes in some residues that generate differences in electrostatic surface in the open groove region, supporting the participation of six members of multifamily proteins in this specific process. The data suggests participation of different expansin proteins in the dissembling and remodeling of the complex cell wall matrix during the reorientation response to inclination. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Dynamics of 4-oxo-TEMPO-d16-15N nitroxide-propylene glycol system studied by ESR and ESE in liquid and glassy state in temperature range 10-295 K

    NASA Astrophysics Data System (ADS)

    Goslar, Janina; Hoffmann, Stanislaw K.; Lijewski, Stefan

    2016-08-01

    ESR spectra and electron spin relaxation of nitroxide radical in 4-oxo-TEMPO-d16-15N in propylene glycol were studied at X-band in the temperature range 10-295 K. The spin-lattice relaxation in the liquid viscous state determined from the resonance line shape is governed by three mechanisms occurring during isotropic molecular reorientations. In the glassy state below 200 K the spin-lattice relaxation, phase relaxation and electron spin echo envelope modulations (ESEEM) were studied by pulse spin echo technique using 2-pulse and 3-pulse induced signals. Electron spin-lattice relaxation is governed by a single non-phonon relaxation process produced by localized oscillators of energy 76 cm-1. Electron spin dephasing is dominated by a molecular motion producing a resonance-type peak in the temperature dependence of the dephasing rate around 120 K. The origin of the peak is discussed and a simple method for the peak shape analysis is proposed, which gives the activation energy of a thermally activated motion Ea = 7.8 kJ/mol and correlation time τ0 = 10-8 s. The spin echo amplitude is strongly modulated and FT spectrum contains a doublet of lines centered around the 2D nuclei Zeeman frequency. The splitting into the doublet is discussed as due to a weak hyperfine coupling of nitroxide unpaired electron with deuterium of reorienting CD3 groups.

  2. Shape-assisted body reorientation enhances trafficability through cluttered terrain

    NASA Astrophysics Data System (ADS)

    Li, Chen; Pullin, Andrew; Haldane, Duncan; Fearing, Ronald; Full, Robert

    2014-11-01

    Many birds and fishes have slender, streamlined bodies that reduce fluid dynamic drag and allow fast and efficient locomotion. Similarly, numerous terrestrial animals run through cluttered terrain where 3-D, multi-component obstacles like grass, bushes, trees, walls, doors, and pillars also resist motion, but it is unknown whether their body shape plays a major role. Here, we challenged discoid cockroaches that possess a rounded, thin, nearly ellipsoidal body to run through tall, narrowly spaced, grass-like beams. The animals primarily rolled their body to the side to maneuver through the obstacle gaps. Reduction of body roundness by artificial shells inhibited this side roll maneuver, resulting in a lower traversal probability and a longer traversal time (P < 0.001, ANOVA). Inspired by this discovery, we added a cockroach-like, rounded exoskeleton shell to a legged robot of a nearly cuboidal body. The rounded shell enabled the robot to use passive side rolling to maneuver through beams. To explain the mechanism, we developed a simple physics model to construct an energy landscape of the body-terrain interaction, which allowed estimation of body forces and torques exerted by the beams. Our model revealed that, by passive interaction with the terrain, a rounded body (ellipsoid) rolled more easily than an angular body (cuboid) to access energy valleys between energy barriers caused by obstacles. Our study is the first to demonstrate that a terradynamically ``streamlined'' shape can reduce terrain resistance and enhance trafficability by assisting body reorientation.

  3. The development of involuntary and voluntary attention from childhood to adulthood: a combined behavioral and event-related potential study.

    PubMed

    Wetzel, Nicole; Widmann, Andreas; Berti, Stefan; Schröger, Erich

    2006-10-01

    This study investigated auditory involuntary and voluntary attention in children aged 6-8, 10-12 and young adults. The strength of distracting stimuli (20% and 5% pitch changes) and the amount of allocation of attention were varied. In an auditory distraction paradigm event-related potentials (ERPs) and behavioral data were measured from subjects either performing a sound duration discrimination task or watching a silent video. Pitch changed sounds caused prolonged reaction times and decreased hit rates in all age groups. Larger distractors (20%) caused stronger distraction in children, but not in adults. The amplitudes of mismatch negativity (MMN), P3a, and reorienting negativity (RON) were modulated by age and by voluntary attention. P3a was additionally affected by distractor strength. Maturational changes were also observed in the amplitudes of P1 (decreasing with age) and N1 (increasing with age). P2-modulation by voluntary attention was opposite in young children and adults. Results suggest quantitative and qualitative changes in auditory voluntary and involuntary attention and distraction during development. The processing steps involved in distraction (pre-attentive change detection, attention switch, reorienting) are functional in children aged 6-8 but reveal characteristic differences to those of young adults. In general, distractibility as indicated by behavioral and ERP measures decreases from childhood to adulthood. Behavioral and ERP markers for different processing stages involved in voluntary and involuntary attention reveal characteristic developmental changes from childhood to young adulthood.

  4. True Polar Wander of Mercury

    NASA Astrophysics Data System (ADS)

    Keane, J. T.; Matsuyama, I.

    2018-05-01

    We use new MESSENGER gravity data to investigate how impact basins and volcanic provinces alter Mercury's moments of inertia. We find that Mercury has reoriented tens of degrees over its history, affecting tectonics, volatiles, and more.

  5. Low gravity liquid motions in spacecraft

    NASA Technical Reports Server (NTRS)

    Dodge, Franklin T.

    1987-01-01

    Low gravity liquid motions in a spacecraft are discussed in outline form and on viewgraphs. Free-surface sloshing, liquid draining, liquid reorientation, and sloshing in a bladdered tank are covered. Conclusions and recommendations are given.

  6. SPHERES ultrasound beacon tester floats in Node 1 during Expedition 8

    NASA Image and Video Library

    2004-03-24

    ISS008-E-19132 (24 March 2004) --- The Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) Beacon / Beacon Tester floats in the Unity node of the International Space Station.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    de Miguel, E.; Rull, L.F.; Gubbins, K.E.

    Using molecular-dynamics computer simulation, we study the dynamical behavior of the isotropic and nematic phases of highly anisotropic molecular fluids. The interactions are modeled by means of the Gay-Berne potential with anisotropy parameters {kappa}=3 and {kappa}{prime}=5. The linear-velocity autocorrelation function shows no evidence of a negative region in the isotropic phase, even at the higher densities considered. The self-diffusion coefficient parallel to the molecular axis shows an anomalous increase with density as the system enters the nematic region. This enhancement in parallel diffusion is also observed in the isotropic side of the transition as a precursor effect. The molecular reorientationmore » is discussed in the light of different theoretical models. The Debye diffusion model appears to explain the reorientational mechanism in the nematic phase. None of the models gives a satisfactory account of the reorientation process in the isotropic phase.« less

  8. Communication: On the origin of the non-Arrhenius behavior in water reorientation dynamics.

    PubMed

    Stirnemann, Guillaume; Laage, Damien

    2012-07-21

    We combine molecular dynamics simulations and analytic modeling to determine the origin of the non-Arrhenius temperature dependence of liquid water's reorientation and hydrogen-bond dynamics between 235 K and 350 K. We present a quantitative model connecting hydrogen-bond exchange dynamics to local structural fluctuations, measured by the asphericity of Voronoi cells associated with each water molecule. For a fixed local structure the regular Arrhenius behavior is recovered, and the global anomalous temperature dependence is demonstrated to essentially result from a continuous shift in the unimodal structure distribution upon cooling. The non-Arrhenius behavior can thus be explained without invoking an equilibrium between distinct structures. In addition, the large width of the homogeneous structural distribution is shown to cause a growing dynamical heterogeneity and a non-exponential relaxation at low temperature.

  9. Global-scale tectonic patterns on Pluto

    NASA Astrophysics Data System (ADS)

    Matsuyama, I.; Keane, J. T.; Kamata, S.

    2016-12-01

    The New Horizons spacecraft revealed a global-scale tectonic pattern on the surface of Pluto which is presumably related to its formation and early evolution. Changes in the rotational and tidal potentials, expansion, and loading can generate stresses capable of producing global-scale tectonic patterns. The current alignment of Sputnik Planum with the tidal axis suggests a reorientation of Pluto relative to the rotation and tidal axes, or true polar wander. This reorientation can be driven by mass loading associated with Sputnik Planum. We developed a general theoretical formalism for the calculation of tectonic patterns due to a variety of process including true polar wander, loading, and expansion. The formalism is general enough to be applicable to non-axisymmetric loads. We illustrate that the observed global-scale tectonic pattern can be explained by stresses generated by true polar wander, Sputnik Planum loading, and expansion.

  10. Calorimetric, FTIR and 1H NMR measurements in combination with DFT calculations for monitoring solid-state changes of dynamics of sibutramine hydrochloride.

    PubMed

    Pajzderska, Aleksandra; Chudoba, Dorota M; Mielcarek, Jadwiga; Wąsicki, Jan

    2012-10-01

    Two forms of sibutramine hydrochloride, monohydrate and anhydrous, have been investigated by calorimetric methods, Fourier transform infrared (FTIR) absorption and (1) H nuclear magnetic resonance (NMR) measurements as well as by density functional theory (DFT) of vibrational frequencies and infrared intensities, calculations of steric hindrances and Monte Carlo simulations. The results of FTIR spectra combined with DFT calculations permitted identification of the bands corresponding to the dynamics and vibrations of water molecules. NMR study and Monte Carlo simulations revealed the occurrence of reorientation jumps of the methyl groups in sibutramine cation and also revealed that the reorientation of isopropyl group is possible only in sibutramine monohydrate hydrochloride. The hydration of sibutramine hydrochloride causes a change in the conformation of sibutramine cation. Copyright © 2012 Wiley-Liss, Inc.

  11. Element-resolved magnetism across the temperature- and pressure-induced spin reorientation in MnBi

    DOE PAGES

    Choi, Yongseong; Jiang, Xiujuan; Bi, Wenli; ...

    2016-11-01

    Rare-earth free permanent magnet MnBi (NiAs-type crystal structure) displays strong magnetic anisotropy above its 90 K spin reorientation transition (SRT). X-ray magnetic circular dichroism (XMCD) shows induced magnetism in Bi 5d band, which is strongly coupled to the magnetism of Mn. A clear increase in Bi orbital-to-spin moment ratio is observed above the SRT. Hydrostatic pressure mimics the e*ect of temperature on the SRT, and the pressure effect also leads to anisotropic lattice contraction, which is known to be induced by cooling. These results reveal that temperature and pressure can similarly induce the coupled structural and magnetic responses, suggesting themore » importance of the anisotropic lattice change and Mn-Bi hybridization to the magnetic anisotropy change across the SRT.« less

  12. Magnetic stripe domains of [Pt/Co/Cu]{sub 10} multilayer near spin reorientation transition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, L.; Liang, J. H.; Xiao, X.

    The dependence of magnetic anisotropy, magnetic domain patterns and magnetization reversal processes in [Pt/Co(t{sub Co})/Cu]{sub 10} film stack epitaxied on Cu (111) substrate have been studied as a function of the Co layer thickness t{sub Co}, by magneto-optic polar Kerr magnetometry and microscopy. We find the film undergoes spin reorientation transition from out-of-plane to in-plane as t{sub Co} increases. The SRT thickness is verified by Rotating-field Magneto-Optic Kerr effect method. The film exhibits the stripe domain structures at remanence with the width decreasing while t{sub Co} approaches SRT. As demonstrated by the first order reversal curve measurement, the magnetization reversalmore » process encompasses irreversible domain nucleation, domain annihilation at large field and reversible domain switching near remanence.« less

  13. Role of the Cotyledons in the Phototropic Response of Lavatera cretica Seedlings.

    PubMed

    Schwartz, A; Koller, D

    1980-07-01

    Young seedlings of Lavatera cretica L. exhibit positive phototropism. The hypocotyl perceives unilateral illumination with blue light and curves towards the light source by unequal growth. In addition, the cotyledonary laminas perceive the vectorial component of unilateral illumination with blue light and reorient normal to the beam by creating a turgor differential in their pulvini. Excision of one cotyledon resulted in negative organotropic curvature of the hypocotyl, away from the remaining cotyledon. Illumination of the cotyledonary lamina did not participate in the phototropic curvature of the hypocotyl, so long as the lamina was free to reorient to face the beam. When the lamina was continuously exposed to vectorial photoexcitation, elongation of the hypocotyl on the side carrying the cotyledon could be enhanced, or inhibited, depending on the direction of the beam striking its lamina.

  14. Statolith sedimentation kinetics and force transduction to the cortical endoplasmic reticulum in gravity-sensing Arabidopsis columella cells.

    PubMed

    Leitz, Guenther; Kang, Byung-Ho; Schoenwaelder, Monica E A; Staehelin, L Andrew

    2009-03-01

    The starch statolith hypothesis of gravity sensing in plants postulates that the sedimentation of statoliths in specialized statocytes (columella cells) provides the means for converting the gravitational potential energy into a biochemical signal. We have analyzed the sedimentation kinetics of statoliths in the central S2 columella cells of Arabidopsis thaliana. The statoliths can form compact aggregates with gap sizes between statoliths approaching <30 nm. Significant intra-aggregate sliding motions of individual statoliths suggest a contribution of hydrodynamic forces to the motion of statoliths. The reorientation of the columella cells accelerates the statoliths toward the central cytoplasm within <1 s of reorientation. During the subsequent sedimentation phase, the statoliths tend to move at a distance to the cortical endoplasmic reticulum (ER) boundary and interact only transiently with the ER. Statoliths moved by laser tweezers against the ER boundary experience an elastic lift force upon release from the optical trap. High-resolution electron tomography analysis of statolith-to-ER contact sites indicate that the weight of statoliths is sufficient to locally deform the ER membranes that can potentially activate mechanosensitive ion channels. We suggest that in root columella cells, the transduction of the kinetic energy of sedimenting statoliths into a biochemical signal involves a combination of statolith-driven motion of the cytosol, statolith-induced deformation of the ER membranes, and a rapid release of kinetic energy from the ER during reorientation to activate mechanosensitive sites within the central columella cells.

  15. Statolith Sedimentation Kinetics and Force Transduction to the Cortical Endoplasmic Reticulum in Gravity-Sensing Arabidopsis Columella Cells[W][OA

    PubMed Central

    Leitz, Guenther; Kang, Byung-Ho; Schoenwaelder, Monica E.A.; Staehelin, L. Andrew

    2009-01-01

    The starch statolith hypothesis of gravity sensing in plants postulates that the sedimentation of statoliths in specialized statocytes (columella cells) provides the means for converting the gravitational potential energy into a biochemical signal. We have analyzed the sedimentation kinetics of statoliths in the central S2 columella cells of Arabidopsis thaliana. The statoliths can form compact aggregates with gap sizes between statoliths approaching <30 nm. Significant intra-aggregate sliding motions of individual statoliths suggest a contribution of hydrodynamic forces to the motion of statoliths. The reorientation of the columella cells accelerates the statoliths toward the central cytoplasm within <1 s of reorientation. During the subsequent sedimentation phase, the statoliths tend to move at a distance to the cortical endoplasmic reticulum (ER) boundary and interact only transiently with the ER. Statoliths moved by laser tweezers against the ER boundary experience an elastic lift force upon release from the optical trap. High-resolution electron tomography analysis of statolith-to-ER contact sites indicate that the weight of statoliths is sufficient to locally deform the ER membranes that can potentially activate mechanosensitive ion channels. We suggest that in root columella cells, the transduction of the kinetic energy of sedimenting statoliths into a biochemical signal involves a combination of statolith-driven motion of the cytosol, statolith-induced deformation of the ER membranes, and a rapid release of kinetic energy from the ER during reorientation to activate mechanosensitive sites within the central columella cells. PMID:19276442

  16. Carbon Incorporation and Anion Dynamics as Synergistic Drivers for Ultrafast Diffusion in Superionic LiCB 11H 12 and NaCB 11H 12

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dimitrievska, Mirjana; Shea, Patrick; Kweon, Kyoung E.

    The disordered phases ofLiCB 11H 12 and NaCB 11H 12 possess superb superionic conductivities that make them suitable as solid electrolytes. In these materials, cation diffusion correlates with high orientational mobilities of the CB 11H 12 - anions; however, the precise relationship has yet to be demonstrated. In this work, ab initio molecular dynamics and quasielastic neutron scattering are combined to probe anion reorientations and their mechanistic connection to cation mobility over a range of timescales and temperatures. It is found that anions do not rotate freely, but rather transition rapidly between orientations defined by the cation sublattice symmetry. Themore » symmetry-breaking carbon atom in CB 11H 12 - also plays a critical role by perturbing the energy landscape along the instantaneous orientation of the anion dipole, which couples fluctuations in the cation probability density directly to the anion motion. Anion reorientation rates exceed 3 x 10 10 s -1, suggesting the underlying energy landscape fluctuates dynamically on diffusion-relevant timescales. Furthermore, carbon is found to modify the orientational preferences of the anions and aid rotational mobility, creating additional symmetry incompatibilities that inhibit ordering. The results suggest that synergy between the anion reorientational dynamics and the carbon-modified cation-anion interaction accounts for the higher ionic conductivity in CB 11H 12 - salts compared with B 12H 12 2-.« less

  17. Novel Methods for Analysing Bacterial Tracks Reveal Persistence in Rhodobacter sphaeroides

    PubMed Central

    Rosser, Gabriel; Fletcher, Alexander G.; Wilkinson, David A.; de Beyer, Jennifer A.; Yates, Christian A.; Armitage, Judith P.; Maini, Philip K.; Baker, Ruth E.

    2013-01-01

    Tracking bacteria using video microscopy is a powerful experimental approach to probe their motile behaviour. The trajectories obtained contain much information relating to the complex patterns of bacterial motility. However, methods for the quantitative analysis of such data are limited. Most swimming bacteria move in approximately straight lines, interspersed with random reorientation phases. It is therefore necessary to segment observed tracks into swimming and reorientation phases to extract useful statistics. We present novel robust analysis tools to discern these two phases in tracks. Our methods comprise a simple and effective protocol for removing spurious tracks from tracking datasets, followed by analysis based on a two-state hidden Markov model, taking advantage of the availability of mutant strains that exhibit swimming-only or reorientating-only motion to generate an empirical prior distribution. Using simulated tracks with varying levels of added noise, we validate our methods and compare them with an existing heuristic method. To our knowledge this is the first example of a systematic assessment of analysis methods in this field. The new methods are substantially more robust to noise and introduce less systematic bias than the heuristic method. We apply our methods to tracks obtained from the bacterial species Rhodobacter sphaeroides and Escherichia coli. Our results demonstrate that R. sphaeroides exhibits persistence over the course of a tumbling event, which is a novel result with important implications in the study of this and similar species. PMID:24204227

  18. Carbon Incorporation and Anion Dynamics as Synergistic Drivers for Ultrafast Diffusion in Superionic LiCB 11H 12 and NaCB 11H 12

    DOE PAGES

    Dimitrievska, Mirjana; Shea, Patrick; Kweon, Kyoung E.; ...

    2018-02-20

    The disordered phases ofLiCB 11H 12 and NaCB 11H 12 possess superb superionic conductivities that make them suitable as solid electrolytes. In these materials, cation diffusion correlates with high orientational mobilities of the CB 11H 12 - anions; however, the precise relationship has yet to be demonstrated. In this work, ab initio molecular dynamics and quasielastic neutron scattering are combined to probe anion reorientations and their mechanistic connection to cation mobility over a range of timescales and temperatures. It is found that anions do not rotate freely, but rather transition rapidly between orientations defined by the cation sublattice symmetry. Themore » symmetry-breaking carbon atom in CB 11H 12 - also plays a critical role by perturbing the energy landscape along the instantaneous orientation of the anion dipole, which couples fluctuations in the cation probability density directly to the anion motion. Anion reorientation rates exceed 3 x 10 10 s -1, suggesting the underlying energy landscape fluctuates dynamically on diffusion-relevant timescales. Furthermore, carbon is found to modify the orientational preferences of the anions and aid rotational mobility, creating additional symmetry incompatibilities that inhibit ordering. The results suggest that synergy between the anion reorientational dynamics and the carbon-modified cation-anion interaction accounts for the higher ionic conductivity in CB 11H 12 - salts compared with B 12H 12 2-.« less

  19. The Role of Visual Cues in Microgravity Spatial Orientation

    NASA Technical Reports Server (NTRS)

    Oman, Charles M.; Howard, Ian P.; Smith, Theodore; Beall, Andrew C.; Natapoff, Alan; Zacher, James E.; Jenkin, Heather L.

    2003-01-01

    In weightlessness, astronauts must rely on vision to remain spatially oriented. Although gravitational down cues are missing, most astronauts maintain a subjective vertical -a subjective sense of which way is up. This is evidenced by anecdotal reports of crewmembers feeling upside down (inversion illusions) or feeling that a floor has become a ceiling and vice versa (visual reorientation illusions). Instability in the subjective vertical direction can trigger disorientation and space motion sickness. On Neurolab, a virtual environment display system was used to conduct five interrelated experiments, which quantified: (a) how the direction of each person's subjective vertical depends on the orientation of the surrounding visual environment, (b) whether rolling the virtual visual environment produces stronger illusions of circular self-motion (circular vection) and more visual reorientation illusions than on Earth, (c) whether a virtual scene moving past the subject produces a stronger linear self-motion illusion (linear vection), and (d) whether deliberate manipulation of the subjective vertical changes a crewmember's interpretation of shading or the ability to recognize objects. None of the crew's subjective vertical indications became more independent of environmental cues in weightlessness. Three who were either strongly dependent on or independent of stationary visual cues in preflight tests remained so inflight. One other became more visually dependent inflight, but recovered postflight. Susceptibility to illusions of circular self-motion increased in flight. The time to the onset of linear self-motion illusions decreased and the illusion magnitude significantly increased for most subjects while free floating in weightlessness. These decreased toward one-G levels when the subject 'stood up' in weightlessness by wearing constant force springs. For several subjects, changing the relative direction of the subjective vertical in weightlessness-either by body rotation or by simply cognitively initiating a visual reorientation-altered the illusion of convexity produced when viewing a flat, shaded disc. It changed at least one person's ability to recognize previously presented two-dimensional shapes. Overall, results show that most astronauts become more dependent on dynamic visual motion cues and some become responsive to stationary orientation cues. The direction of the subjective vertical is labile in the absence of gravity. This can interfere with the ability to properly interpret shading, or to recognize complex objects in different orientations.

  20. Reorientation Motion and Preferential Interactions of a Peptide in Denaturants and Osmolyte.

    PubMed

    Jas, Gouri S; Rentchler, Eric C; Słowicka, Agnieszka M; Hermansen, John R; Johnson, Carey K; Middaugh, C Russell; Kuczera, Krzysztof

    2016-03-31

    Fluorescence anisotropy decay measurements and all atom molecular dynamics simulations are used to characterize the orientational motion and preferential interaction of a peptide, N-acetyl-tryptophan-amide (NATA) containing two peptide bonds, in aqueous, urea, guanidinium chloride (GdmCl), and proline solution. Anisotropy decay measurements as a function of temperature and concentration showed moderate slowing of reorientations in urea and GdmCl and very strong slowing in proline solution, relative to water. These effects deviate significantly from simple proportionality of peptide tumbling time to solvent viscosity, leading to the investigation of microscopic preferential interaction behavior through molecular dynamics simulations. Examination of the interactions of denaturants and osmolyte with the peptide backbone uncovers the presence of strongest interaction with urea, intermediate with proline, and weakest with GdmCl. In contrast, the strongest preferential solvation of the peptide side chain is by the nonpolar part of the proline zwitterion, followed by urea, and GdmCl. Interestingly, the local density of urea around the side chain is higher, but the GdmCl distribution is more organized. Thus, the computed preferential solvation of the side chain by the denaturants and osmolyte can account for the trend in reorientation rates. Analysis of water structure and its dynamics uncovered underlying differences between urea, GdmCl, and proline. Urea exerted the smallest perturbation of water behavior. GdmCl had a larger effect on water, slowing kinetics and stabilizing interactions. Proline had the largest overall interactions, exhibiting a strong stabilizing effect on both water-water and water-peptide hydrogen bonds. The results for this elementary peptide system demonstrate significant differences in microscopic behavior of the examined solvent environments. For the commonly used denaturants, urea tends to form disorganized local aggregates around the peptide groups and has little influence on water, while GdmCl only forms specific interactions with the side chain and tends to destabilize water structure. The protective osmolyte proline has the strongest and most specific interactions with the tryptophan side chain, and also stabilizes both water-water and water-peptide hydrogen bonds. Our results strongly suggest protein or peptide denaturation triggered by urea occurs by direct interaction, whereas GdmCl interacts favorably with side chains and destabilizes peptide-water hydrogen bonds. The stabilization of biopolymers by an osmolyte such as proline is governed by favorable preferential interaction with the side chains and stabilization of water.

  1. Right Unilateral Ultrabrief Pulse ECT in Geriatric Depression: Phase 1 of the PRIDE Study.

    PubMed

    Kellner, Charles H; Husain, Mustafa M; Knapp, Rebecca G; McCall, W Vaughn; Petrides, Georgios; Rudorfer, Matthew V; Young, Robert C; Sampson, Shirlene; McClintock, Shawn M; Mueller, Martina; Prudic, Joan; Greenberg, Robert M; Weiner, Richard D; Bailine, Samuel H; Rosenquist, Peter B; Raza, Ahmad; Kaliora, Styliani; Latoussakis, Vassilios; Tobias, Kristen G; Briggs, Mimi C; Liebman, Lauren S; Geduldig, Emma T; Teklehaimanot, Abeba A; Lisanby, Sarah H

    2016-11-01

    The Prolonging Remission in Depressed Elderly (PRIDE) study evaluated the efficacy of right unilateral ultrabrief pulse electroconvulsive therapy (ECT) combined with venlafaxine for the treatment of geriatric depression. PRIDE was a two-phase multisite study. Phase 1 was an acute course of right unilateral ultrabrief pulse ECT, combined with open-label venlafaxine at seven academic medical centers. In phase 2 (reported separately), patients who had remitted were randomly assigned to receive pharmacotherapy (venlafaxine plus lithium) or pharmacotherapy plus continuation ECT. In phase 1, depressed patients received high-dose ECT (at six times the seizure threshold) three times per week. Venlafaxine was started during the first week of treatment and continued throughout the study. The primary outcome measure was remission, assessed with the 24-item Hamilton Depression Rating Scale (HAM-D), which was administered three times per week. Secondary outcome measures were post-ECT reorientation and safety. Paired t tests were used to estimate and evaluate the significance of change from baseline in HAM-D scores. Of 240 patients who entered phase 1 of the study, 172 completed it. Overall, 61.7% (148/240) of all patients met remission criteria, 10.0% (24/240) did not remit, and 28.3% (68/240) dropped out; 70% (169/240) met response criteria. Among those who remitted, the mean decrease in HAM-D score was 24.7 points (95% CI=23.4, 25.9), with a mean final score of 6.2 (SD=2.5) and an average change from baseline of 79%. The mean number of ECT treatments to remission was 7.3 (SD=3.1). Right unilateral ultrabrief pulse ECT, combined with venlafaxine, is a rapidly acting and highly effective treatment option for depressed geriatric patients, with excellent safety and tolerability. These data add to the evidence base supporting the efficacy of ECT to treat severe depression in elderly patients.

  2. Time trends in the etiology of chronic pancreatitis in South India.

    PubMed

    Rajesh, Gopalakrishna; Girish, Banavara Narasimhamurthy; Panicker, Suprabha; Balakrishnan, Vallath

    2014-01-01

    Recent reports indicate a decline in prevalence of classical tropical chronic pancreatitis (TCP). We studied the etiologies and risk factors over a 14-year period at a tertiary care university hospital. We compared the etiology in chronic pancreatitis (CP) patients presenting and followed-up in our Pancreas Clinic over two time periods (2000-06 and 2007-13). Idiopathic chronic pancreatitis (ICP) was the predominant etiology seen over the two time periods. However an increase in prevalence of alcoholic chronic pancreatitis (ACP) during the latter time period suggests that it may be emerging as a dominant etiology over recent years. Hypertriglyceridemia and hyperparathyroidism were uncommon causes of non-alcoholic CP. Autoimmune pancreatitis was noted only during 2007-13, but remains a rare cause of CP. There are multiple risk factors for CP in our population. The high prevalence of ICP indicates need closer examination of risk factors and ICP pathogenesis. ACP appears to be emerging as a dominant cause of CP which suggests a need to reorient preventive strategies.

  3. Dynamic spectral shifts of molecular anions in organic glasses. [Pulse radiolysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huddleston, R.K.; Miller, J.R.

    1982-06-24

    Time-dependent spectra of the radical anions of pyromellitic dianhydride and p-dinitrobenzene have been observed after formation by pulse radiolysis in frozen 2-methyltetrahydrofuran and triacetin glasses. At temperatures near the glass transition, the spectra shift toward the blue over the entire observed time range 100 ns to 100 s), while at temperatures well below the glass transition, the spectral shifts can be stopped or greatly slowed. The magnitudes of the shifts are not large (typically approx. = to 10 nm), but because they are larger than the vibrational line widths, dramatic kinetics may be observed: the absorbance grows or decays bymore » more than a factor of five at some wavelengths. The observations are consistent with a solvent molecule reorientation mechanism for spectral shifts of molecular ions in low-temperature organic glasses. 6 figures.« less

  4. Surface settling in partially filled containers upon step reduction in gravity

    NASA Technical Reports Server (NTRS)

    Weislogel, Marl M.; Ross, Howard D.

    1990-01-01

    A large literature exists concerning the equilibrium configurations of free liquid/gas surfaces in reduced gravity environments. Such conditions generally yield surfaces of constant curvature meeting the container wall at a particular (contact) angle. The time required to reach and stabilize about this configuration is less studied for the case of sudden changes in gravity level, e.g. from normal- to low-gravity, as can occur in many drop tower experiments. The particular interest here was to determine the total reorientation time for such surfaces in cylinders (mainly), as a function primarily of contact angle and kinematic viscosity, in order to aid in the development of drop tower experiment design. A large parametric range of tests were performed and, based on an accompanying scale analysis, the complete data set was correlated. The results of other investigations are included for comparison.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zheng, Renhui; Sun, Yuanyuan; Song, Kai

    Recent experimental studies have shown that the vibrational dynamics of free OH groups at the water-air interface is significantly different from that in bulk water. In this work, by performing molecular dynamics simulations and mixed quantum/classical calculations, we investigate different vibrational energy transfer pathways of free OH groups at the water-air interface. The calculated intramolecular vibrational energy transfer rate constant and the free OH bond reorientation time scale agree well with the experiment. It is also found that, due to the small intermolecular vibrational couplings, the intermolecular vibrational energy transfer pathway that is very important in bulk water plays amore » much less significant role in the vibrational energy relaxation of the free OH groups at the water-air interface.« less

  6. Judging sex.

    PubMed

    Tuerkheimer, Deborah

    2012-09-01

    This Article explores the curious jurisprudence of sexual patterns and how it constructs female sexuality. In modern rape law, the "unchaste character inference" expressly prohibited by the rape shield endures. Though the boundaries that circumscribe appropriate sexual conduct have shifted over time, courts persist in making normative judgments about women's sexuality. Cloaked in the legitimizing rhetoric of sexual patterns, retrograde notions of deviancy are substituting for rational deliberation on the question of consent. As rape shield law enters its fourth decade, it continues to defy reason, both in application and in theory. The proposed evidentiary approach promises to improve judicial decision making in rape cases, while reorienting the law toward the female sexual subject and the contingency of her consent.

  7. Development and Characterization of Liquid Crystal-Gold Nanoparticle Hybrid Materials for Optical Applications

    NASA Astrophysics Data System (ADS)

    Quint, Makiko T.

    Hybrid material, mixtures of two or more materials with new properties, represents an exciting class of new materials for a variety of potential applications such as displays, optoelectronics, and sensors due to their unique physical and optical properties. The scope of this dissertation is to produce two new plasmonic applications by combining liquid crystals with gold nanoparticles. The first application is gold nanoparticle coated liquid crystal thin film. Most liquid crystal (LC) thin films require external voltage to reorient LC molecules. Recent advances in optical controlling technology of LC molecule behavior, resulting in the reduction of energy consumption, have stimulated research and development of new LC thin films. In order to re-orient LC molecules by just using light, the common approach is to include either a photo-responsive LC host, one that require high power light and severely narrows the range of usable materials, or add photo-active dye or polymer layer, photodegradation over time. Our work designing an all-optical method for LC re-orientation that overcomes all the limitations mentioned above. We have successfully both in- and out-of-plane spatial orientation of nematic liquid crystal (LC) molecules by leveraging the highly localized electric fields produced in the near-field regime of a gold nanoparticle (AuNP) layer. This re-orientation of LC molecules in thin LC-AuNP film is all-optical, driven by a small resonance excitation power with the localized surface plasmon absorption of the AuNPs at room temperature. The second application is LC mediated nano-assembled gold microcapsules. This application has a potential in controlled-release cargo-style delivery system. Targeted delivery systems with controlled release mechanisms have been the subject of extensive research more than fifty years. One is to control the release process remotely by using optical excitation. Optical actuation of delivery capsules, which plasmonic nanoparticle such as gold, allows rapid release at specific locations and uses the photothermal effect to unload contents. Almost all gold-based delivery applications including Au coated nanocrystals or AuNPs with soft materials like gels and polymers are not suitable for control release applications in real life since these applications do not provide robust leakage-free containment lower than the American National Standards Institute (ANSI) maximum permissible light exposure limit. We have successfully managed the difficulties mentioned above and produced a new gold-based delivery application. The application is spherical capsules with a densely packed wall of AuNPs. The rigid capsule wall allows encapsulation of cargo that can be contained, virtually leakage-free, over several months. Further, by leveraging LSPR of AuNPs, we can rupture the microshells using optical excitation with ultralow power (< 2 mW), controllably and rapidly releasing the encapsulated contents in less than 5 seconds. Our results exhibiting the capture and optically regulated release of encapsulated substances are a novel platform that combines controlled-release cargo-style delivery and photothermal therapy in one versatile and multifunctional unit. Both our applications are overcoming current limitations and promising future research directions towards the next generation of LC-AuNPs hybrid material research and developments.

  8. Intersection of Social Institutions with Civic Development

    ERIC Educational Resources Information Center

    Youniss, James; Hart, Daniel

    2005-01-01

    We propose that institutions can serve as a resource to promote civic identity in youth from low-wealth and other settings. We show how recent studies support this proposition and can constructively reorient developmental research and theory.

  9. Canadian Business Schools: Going out of Business?

    ERIC Educational Resources Information Center

    Dobni, Dawn; Dobni, Brooke

    1996-01-01

    Using Porter's five-forces model (potential entrants, suppliers, buyers, rivalry, substitutes) to analyze competition in Canadian university business schools, the authors conclude that schools are becoming increasingly vulnerable to competitive pressures and that strategic reorientation is necessary. (SK)

  10. Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) Vertigo Test

    NASA Image and Video Library

    2013-11-10

    ISS037-E-028591 (10 Nov. 2013) --- NASA astronaut Rick Mastracchio (left) and Japan Aerospace Exploration Agency astronaut Koichi Wakata, both Expedition 38 flight engineers, work in the Kibo laboratory of the International Space Station.

  11. A Framework for the Development of Automatic DFA Method to Minimize the Number of Components and Assembly Reorientations

    NASA Astrophysics Data System (ADS)

    Alfadhlani; Samadhi, T. M. A. Ari; Ma’ruf, Anas; Setiasyah Toha, Isa

    2018-03-01

    Assembly is a part of manufacturing processes that must be considered at the product design stage. Design for Assembly (DFA) is a method to evaluate product design in order to make it simpler, easier and quicker to assemble, so that assembly cost is reduced. This article discusses a framework for developing a computer-based DFA method. The method is expected to aid product designer to extract data, evaluate assembly process, and provide recommendation for the product design improvement. These three things are desirable to be performed without interactive process or user intervention, so product design evaluation process could be done automatically. Input for the proposed framework is a 3D solid engineering drawing. Product design evaluation is performed by: minimizing the number of components; generating assembly sequence alternatives; selecting the best assembly sequence based on the minimum number of assembly reorientations; and providing suggestion for design improvement.

  12. Development of a computational model for astronaut reorientation.

    PubMed

    Stirling, Leia; Willcox, Karen; Newman, Dava

    2010-08-26

    The ability to model astronaut reorientations computationally provides a simple way to develop and study human motion control strategies. Since the cost of experimenting in microgravity is high, and underwater training can lead to motions inappropriate for microgravity, these techniques allow for motions to be developed and well-understood prior to any microgravity exposure. By including a model of the current space suit, we have the ability to study both intravehicular and extravehicular activities. We present several techniques for rotating about the axes of the body and show that motions performed by the legs create a greater net rotation than those performed by the arms. Adding a space suit to the motions was seen to increase the resistance torque and limit the available range of motion. While rotations about the body axes can be performed in the current space suit, the resulting motions generated a reduced rotation when compared to the unsuited configuration. 2010 Elsevier Ltd. All rights reserved.

  13. Superconducting spin valves controlled by spiral re-orientation in B20-family magnets

    NASA Astrophysics Data System (ADS)

    Pugach, N. G.; Safonchik, M.; Champel, T.; Zhitomirsky, M. E.; Lähderanta, E.; Eschrig, M.; Lacroix, C.

    2017-10-01

    We propose a superconducting spin-triplet valve, which consists of a superconductor and an itinerant magnetic material, with the magnet showing an intrinsic non-collinear order characterized by a wave vector that may be aligned in a few equivalent preferred directions under the control of a weak external magnetic field. Re-orienting the spiral direction allows one to controllably modify long-range spin-triplet superconducting correlations, leading to spin-valve switching behavior. Our results indicate that the spin-valve effect may be noticeable. This bilayer may be used as a magnetic memory element for cryogenic nanoelectronics. It has the following advantages in comparison to superconducting spin valves proposed previously: (i) it contains only one magnetic layer, which may be more easily fabricated and controlled; (ii) its ground states are separated by a potential barrier, which solves the "half-select" problem of the addressed switch of memory elements.

  14. Raman study of annealed two-dimensional heterostructure of graphene on hexagonal boron nitride

    NASA Astrophysics Data System (ADS)

    Souibgui, Mourad; Ajlani, Hosni; Cavanna, Antonnella; Oueslati, Meherzi; Meftah, Abdelaziz; Madouri, Ali

    2017-12-01

    In this paper, we investigate stacked 2D graphene layers on hexagonal boron nitride (h-BN). The graphene is obtained by high-quality chemical vapor deposition (CVD) and transferred to the h-BN substrate. We focus our attention on annealing effect at 1040 °C on single graphene layer (SGL) and bilayer graphene (BLG) on h-BN substrate using Raman spectroscopy. Our results show, before annealing, a twist angle θ = 0.63 ° between the SGL and the h-BN substrate and a twist angle 3 ° <θG1G2 < 8 ° between the two graphene layers of the BLG. After annealing, the analysis of the graphene G and 2D bands show a rotational reorientation of the graphene layer with respect to the h-BN substrate. Raman mapping also shows that the rotational reorientation is spatially dependent.

  15. Mechanical adaptability of the Bouligand-type structure in natural dermal armour.

    PubMed

    Zimmermann, Elizabeth A; Gludovatz, Bernd; Schaible, Eric; Dave, Neil K N; Yang, Wen; Meyers, Marc A; Ritchie, Robert O

    2013-01-01

    Arapaima gigas, a fresh water fish found in the Amazon Basin, resist predation by piranhas through the strength and toughness of their scales, which act as natural dermal armour. Arapaima scales consist of a hard, mineralized outer shell surrounding a more ductile core. This core region is composed of aligned mineralized collagen fibrils arranged in distinct lamellae. Here we show how the Bouligand-type (twisted plywood) arrangement of collagen fibril lamellae has a key role in developing their unique protective properties, by using in situ synchrotron small-angle X-ray scattering during mechanical tensile tests to observe deformation mechanisms in the fibrils. Specifically, the Bouligand-type structure allows the lamellae to reorient in response to the loading environment; remarkably, most lamellae reorient towards the tensile axis and deform in tension through stretching/sliding mechanisms, whereas other lamellae sympathetically rotate away from the tensile axis and compress, thereby enhancing the scale's ductility and toughness to prevent fracture.

  16. Zero-Propellant Maneuver[TM] Flight Results for 180 deg ISS Rotation

    NASA Technical Reports Server (NTRS)

    Bedrossian, Nazareth; Bhatt, Sagar; Lammers, Mike; Nguyen, Louis

    2007-01-01

    This paper presents results for the Zero Propellant Maneuver (ZPM) TradeMark attitude control concept flight demonstration. On March 3, 2007, a ZPM was used to reorient the International Space Station 180 degrees without using any propellant. The identical reorientation performed with thrusters would have burned 110lbs of propellant. The ZPM was a pre-planned trajectory used to command the CMG attitude hold controller to perform the maneuver between specified initial and final states while maintaining the CMGs within their operational limits. The trajectory was obtained from a PseudoSpectral solution to a new optimal attitude control problem. The flight test established the breakthrough capability to simultaneously perform a large angle attitude maneuver and momentum desaturation without the need to use thrusters. The flight implementation did not require any modifications to flight software. This approach is applicable to any spacecraft that are controlled by momentum storage devices.

  17. Behaviour of nematic liquid crystals doped with ferroelectric nanoparticles in the presence of an electric field

    NASA Astrophysics Data System (ADS)

    Emdadi, M.; Poursamad, J. B.; Sahrai, M.; Moghaddas, F.

    2018-06-01

    A planar nematic liquid crystal cell (NLC) doped with spherical ferroelectric nanoparticles is considered. Polarisation of the nanoparticles are assumed to be along the NLC molecules parallel and antiparallel to the director with equal probability. The NLC molecules anchoring to the cell walls are considered to be strong, while soft anchoring at the nanoparticles surface is supposed. Behaviour of the NLC molecules and nanoparticles in the presence of a perpendicular electric field to the NLC cell is theoretically investigated. The electric field of the nanoparticles is taken into account in the calculations. Freedericksz transition (FT) threshold field in the presence of nanoparticles is found. Then, the director and particles reorientations for the electric fields larger than the threshold field are studied. Measuring the onset of the nanoparticles reorientation is proposed as a new method for the FT threshold measurement.

  18. Power-controlled transition from standard to negative refraction in reorientational soft matter.

    PubMed

    Piccardi, Armando; Alberucci, Alessandro; Kravets, Nina; Buchnev, Oleksandr; Assanto, Gaetano

    2014-11-25

    Refraction at a dielectric interface can take an anomalous character in anisotropic crystals, when light is negatively refracted with incident and refracted beams emerging on the same side of the interface normal. In soft matter subject to reorientation, such as nematic liquid crystals, the nonlinear interaction with light allows tuning of the optical properties. We demonstrate that in such material a beam of light can experience either positive or negative refraction depending on input power, as it can alter the spatial distribution of the optic axis and, in turn, the direction of the energy flow when traveling across an interface. Moreover, the nonlinear optical response yields beam self-focusing and spatial localization into a self-confined solitary wave through the formation of a graded-index waveguide, linking the refractive transition to power-driven readdressing of copolarized guided-wave signals, with a number of output ports not limited by diffraction.

  19. Root gravitropism

    NASA Technical Reports Server (NTRS)

    Masson, P. H.

    1995-01-01

    When a plant root is reoriented within the gravity field, it responds by initiating a curvature which eventually results in vertical growth. Gravity sensing occurs primarily in the root tip. It may involve amyloplast sedimentation in the columella cells of the root cap, or the detection of forces exerted by the mass of the protoplast on opposite sides of its cell wall. Gravisensing activates a signal transduction cascade which results in the asymmetric redistribution of auxin and apoplastic Ca2+ across the root tip, with accumulation at the bottom side. The resulting lateral asymmetry in Ca2+ and auxin concentration is probably transmitted to the elongation zone where differential cellular elongation occurs until the tip resumes vertical growth. The Cholodny-Went theory proposes that gravity-induced auxin redistribution across a gravistimulated plant organ is responsible for the gravitropic response. However, recent data indicate that the gravity-induced reorientation is more complex, involving both auxin gradient-dependent and auxin gradient-independent events.

  20. Embryonic development during chronic acceleration

    NASA Technical Reports Server (NTRS)

    Smith, A. H.; Abbott, U. K.

    1982-01-01

    Experiments carried out on chicken eggs indicate that the embryo is affected during very early development, especially over the first four days, and during hatching. In the first four days, the brain develops as well as the anlage for all other organs. In addition, the heart commences to function and the extraembryonic membranes that compartmentalize the egg contents form. The latter require an appreciable extension and folding of tissue which may be disrupted by the mechanical load. Observations of embryonic abnormalities that occur during chronic acceleration suggest an inhibition of development of the axial skeleton, which is rarely seen otherwise, a general retardation of embryonic growth, and circulatory problems. The final stages of development (after 18 days) involve the uptake of fluids, the transition to aerial respiration, and the reorientation of the embryo into a normal hatching position. At 4 G mortality is very high during this period, with a majority of embryos failing to reorient into the normal hatching position.

  1. Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules

    PubMed Central

    Chen, Xu; Grandont, Laurie; Li, Hongjiang; Hauschild, Robert; Paque, Sébastien; Abuzeineh, Anas; Rakusová, Hana; Benkova, Eva; Perrot-Rechenmann, Catherine; Friml, Jiří

    2014-01-01

    The prominent and evolutionary ancient effect of the plant hormone auxin is the regulation of cell expansion1. Cell expansion requires ordered cytoskeleton arrangement2 but molecular mechanisms underlying its regulation by signaling molecules including auxin are unknown. Here we show in the model plant Arabidopsis thaliana that in elongating cells exogenous application of auxin or redistribution of endogenous auxin induces very rapid microtubule reorientation from transversal to longitudinal, coherent with the inhibition of cell expansion. This fast auxin effect requires Auxin Binding Protein1 (ABP1) and involves a contribution of downstream signaling components such as ROP6 GTPase, ROP-interactive protein RIC1 and microtubule severing protein Katanin. These components are required for rapid auxin and ABP1-mediated reorientation of microtubules to regulate cell elongation in roots and dark grown hypocotyls as well as asymmetric growth during gravitropic responses. PMID:25409144

  2. Molecular reorientation in assembled CO structures and contrast inversion in STM

    NASA Astrophysics Data System (ADS)

    Niemi, Eeva; Nieminen, Jouko

    2004-10-01

    Recent scanning tunneling microscopy experiments [S. Zöphel, J. Repp, G. Meyer, K.-H. Rieder, Chem. Phys. Lett. 310 (1999) 145; A.J. Heinrich, C.P. Lutz, J.A. Gupta, D.M. Eigler, Science 298 (2002) 1381] for CO on Cu(1 1 1) and Cu(2 1 1) surfaces show CO monomers as dark depressions, whereas dimers and trimers appear as bright patterns. The dark image of a monomer has been shown to result from a destructive interference between two tunneling paths [J. Nieminen, E. Niemi, K.-H. Rieder, Surf. Sci. 552 (2004) L47]. In this Letter, we show how switching between tunneling channels within the through molecule path can be induced by reorientation of a molecule. Hence, a destructive interference between through vacuum and through molecule paths can be reversed into constructive interference by manipulating the adsorbate geometry.

  3. The effect of memory in the stochastic master equation analyzed using the stochastic Liouville equation of motion. Electronic energy migration transfer between reorienting donor-donor, donor-acceptor chromophores

    NASA Astrophysics Data System (ADS)

    Håkansson, Pär; Westlund, Per-Olof

    2005-01-01

    This paper discusses the process of energy migration transfer within reorientating chromophores using the stochastic master equation (SME) and the stochastic Liouville equation (SLE) of motion. We have found that the SME over-estimates the rate of the energy migration compared to the SLE solution for a case of weakly interacting chromophores. This discrepancy between SME and SLE is caused by a memory effect occurring when fluctuations in the dipole-dipole Hamiltonian ( H( t)) are on the same timescale as the intrinsic fast transverse relaxation rate characterized by (1/ T2). Thus the timescale critical for energy-transfer experiments is T2≈10 -13 s. An extended SME is constructed, accounting for the memory effect of the dipole-dipole Hamiltonian dynamics. The influence of memory on the interpretation of experiments is discussed.

  4. Using Personification and Agency Reorientation to Reduce Mental-Health Clinicians’ Stigmatizing Attitudes Toward Patients

    PubMed Central

    Lebowitz, Matthew S.; Ahn, Woo-kyoung

    2015-01-01

    People with mental disorders are strongly stigmatized. Among mental-health professionals, stigmatizing attitudes often manifest as desire for social distance from people with mental disorders. Currently ascendant biomedical conceptualizations of psychopathology could exacerbate this problem by engendering dehumanization, which is linked to prejudice. Given the clinical implications of such an occurrence, the present research tested a possible mitigation strategy. In an online study of 216 U.S. mental-health clinicians, two strategies for mitigating dehumanization in healthcare were tested—personification, highlighting personal traits of people with mental disorders rather than presenting them as malfunctioning brains, and agency reorientation, underscoring people’s ability to make choices and decisions. This approach yielded significantly less desire for social distance, among clinicians, from a person with depression whose symptoms were explained biologically. These findings may suggest an avenue for decreasing stigma in clinical practice. PMID:27766309

  5. Space transportation systems within ESA programmes: Current status and perspectives

    NASA Astrophysics Data System (ADS)

    Delahais, Maurice

    1993-03-01

    An overview of the space transportation aspects of the ESA (European Space Agency) programs as they result from history, present status, and decisions taken at the ministerial level conference in Granada, Spain is presented. The new factors taken into consideration for the long term plan proposed in Munich, Germany, the three strategic options for the reorientation of the ESA long term plan, and the essential elements of space transportation in the Granada long term plan in three areas of space activities, scientific, and commercial launches with expendable launch vehicles, manned flight and in-orbit infrastructure, and future transportation systems are outlined. The new ESA long term plan, in the field of space transportation systems, constitutes a reorientation of the initial program contemplated in previous councils at ministerial level. It aims at balancing the new economic situation with the new avenues of cooperation, and the outcome will be a new implementation of the space transportation systems policy.

  6. Rayleigh-Brillouin scattering studies of the rotation-translation coupling and bulk viscosity relaxation of liquids composed of anisotropic molecules: p-Anisaldehyde and aniline

    NASA Astrophysics Data System (ADS)

    O'Steen, B. L.; Wang, C. H.; Fytas, G.

    1984-04-01

    The coupling of reorientational motion to longitudinal acoustic modes was investigated by studying the Rayleigh-Brillouin spectra of aniline and p-anisaldehyde over a wide range of scattering angles. Aniline and p-anisaldehyde were chosen for investigation since their depolarized spectra at the temperature of interest show a pronounced coupling between orientation and shear modes. The experimental results for attenuation and velocity of the longitudinal waves show that there is indeed relaxation in the shear viscosity. However, shear relaxation due to the coupling of the longitudinal acoustic mode to reorientation plays only a minor role in causing the dispersion of the hypersonic longitudinal waves. To account for the large dispersion, it is essential to consider the mechanism associated with the relaxation of the bulk viscosity through the T-V energy transfer.

  7. Temperature-dependent magnetostriction as the key factor for martensite reorientation in magnetic field

    NASA Astrophysics Data System (ADS)

    L'vov, Victor A.; Kosogor, Anna

    2016-09-01

    The magnetic field application leads to spatially inhomogeneous magnetostriction of twinned ferromagnetic martensite. When the increasing field and magnetostrictive strain reach certain threshold values, the motion of twin boundaries and magnetically induced reorientation (MIR) of twinned martensite start. The MIR leads to giant magnetically induced deformation of twinned martensite. In the present article, the threshold field (TF) and temperature range of observability of MIR were calculated for the Ni-Mn-Ga martensite assuming that the threshold strain (TS) is temperature-independent. The calculations show that if the TS is of the order of 10-4, the TF strongly depends on temperature and MIR can be observed only above the limiting temperature (~220 K). If the TS is of the order of 10-6, the TF weakly depends on temperature and MIR can be observed at extremely low temperatures. The obtained theoretical results are in agreement with available experimental data.

  8. Large Angle Reorientation of a Solar Sail Using Gimballed Mass Control

    NASA Astrophysics Data System (ADS)

    Sperber, E.; Fu, B.; Eke, F. O.

    2016-06-01

    This paper proposes a control strategy for the large angle reorientation of a solar sail equipped with a gimballed mass. The algorithm consists of a first stage that manipulates the gimbal angle in order to minimize the attitude error about a single principal axis. Once certain termination conditions are reached, a regulator is employed that selects a single gimbal angle for minimizing both the residual attitude error concomitantly with the body rate. Because the force due to the specular reflection of radiation is always directed along a reflector's surface normal, this form of thrust vector control cannot generate torques about an axis normal to the plane of the sail. Thus, in order to achieve three-axis control authority a 1-2-1 or 2-1-2 sequence of rotations about principal axes is performed. The control algorithm is implemented directly in-line with the nonlinear equations of motion and key performance characteristics are identified.

  9. A solid-state [sup 13]C NMR study of the molecular motion of ethylene adsorbed on a silver surface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jianxin Wang; Ellis, P.D.

    1993-01-13

    The reorientation of ethylene on a silver catalyst surface has been studied by solid-state [sup 13]C NMR. The static cross-polarization spectra at different temperatures have been measured. Different jump site models are proposed to simulate the experimental results. It was found that the models involving a low number of jump sites are more sensitive to the experimental details. By comparison of the simulated and experimental results, the 6- and 4-site jump models are chosen as the most satisfactory model to fit the experimental spectra. On the basis of this representation, the activation energy derived for the jump process is 4.3more » kJ/mol. From the simulated results, it was concluded that the symmetry axis for the motion of the ethylene at low temperatures ([minus]173 to ca. [minus]45[degrees]C) is perpendicular to the plane of the ethylene molecule. At higher temperatures motion about other axes is initiated such that at room temperature a nearly isotropically averaged [sup 13]C shielding tensor is observed. 20 refs., 9 figs.« less

  10. Patterns of cell elongation in the determination of the final shape in galls of Baccharopelma dracunculifoliae (Psyllidae) on Baccharis dracunculifolia DC (Asteraceae).

    PubMed

    Magalhães, Thiago Alves; de Oliveira, Denis Coelho; Suzuki, Aline Yasko Marinho; Isaias, Rosy Mary dos Santos

    2014-07-01

    Cell redifferentiation, division, and elongation are recurrent processes, which occur during gall development, and are dependent on the cellulose microfibrils reorientation. We hypothesized that changes in the microfibrils orientation from non-galled tissues to galled ones occur and determine the final gall shape. This determination is caused by a new tissue zonation, its hyperplasia, and relative cell hypertrophy. The impact of the insect's activity on these patterns of cell development was herein tested in Baccharopelma dracunculifoliae-Baccharis dracunculifolia system. In this system, the microfibrils are oriented perpendicularly to the longest cell axis in elongated cells and randomly in isodiametric ones, either in non-galled or in galled tissues. The isodiametric cells of the abaxial epidermis in non-galled tissues divided and elongated periclinally, forming the outer gall epidermis. The anticlinally elongated cells of the abaxial palisade layer and the isodiametric cells of the spongy parenchyma originated the gall outer cortex with hypertrophied and periclinally elongated cells. The anticlinally elongated cells of the adaxial palisade layer originated the inner cortex with hypertrophied and periclinally elongated cells in young and mature galls and isodiametric cells in senescent galls. The isodiametric cells of the adaxial epidermis elongated periclinally in the inner gall epidermis. The current investigation demonstrates the role of cellulose microfibril reorientation for gall development. Once many factors other than this reorientation act on gall development, it should be interesting to check the possible relationship of the new cell elongation patterns with the pectic composition of the cell walls.

  11. Is there a geometric module for spatial orientation? Insights from a rodent navigation model.

    PubMed

    Sheynikhovich, Denis; Chavarriaga, Ricardo; Strösslin, Thomas; Arleo, Angelo; Gerstner, Wulfram

    2009-07-01

    Modern psychological theories of spatial cognition postulate the existence of a geometric module for reorientation. This concept is derived from experimental data showing that in rectangular arenas with distinct landmarks in the corners, disoriented rats often make diagonal errors, suggesting their preference for the geometric (arena shape) over the nongeometric (landmarks) cues. Moreover, sensitivity of hippocampal cell firing to changes in the environment layout was taken in support of the geometric module hypothesis. Using a computational model of rat navigation, the authors proposed and tested the alternative hypothesis that the influence of spatial geometry on both behavioral and neuronal levels can be explained by the properties of visual features that constitute local views of the environment. Their modeling results suggest that the pattern of diagonal errors observed in reorientation tasks can be understood by the analysis of sensory information processing that underlies the navigation strategy employed to solve the task. In particular, 2 navigation strategies were considered: (a) a place-based locale strategy that relies on a model of grid and place cells and (b) a stimulus-response taxon strategy that involves direct association of local views with action choices. The authors showed that the application of the 2 strategies in the reorientation tasks results in different patterns of diagonal errors, consistent with behavioral data. These results argue against the geometric module hypothesis by providing a simpler and biologically more plausible explanation for the related experimental data. Moreover, the same model also describes behavioral results in different types of water-maze tasks. Copyright (c) 2009 APA, all rights reserved.

  12. Spin reorientation and Ce-Mn coupling in antiferromagnetic oxypnictide CeMnAsO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Qiang; Tian, Wei; Peterson, Spencer G.

    2015-02-18

    Structure and magnetic properties of high-quality polycrystlline CeMnAsO, a parent compound of the “1111”-type oxypnictides, have been investigated using neutron powder diffraction and magnetization measurements. We find that CeMnAsO undergoes a C-type antiferromagnetic order with Mn 2+(S = 5/2) moments pointing along the c axis below a relatively high Néel temperature of T N = 347(1) K. Below T SR = 35 K, two simultaneous transitions occur where the Mn moments reorient from the c axis to the ab plane preserving the C-type magnetic order, and Ce moments undergo long-range AFM ordering with antiparallel moments pointing in the ab plane.more » Another transition to a noncollinear magnetic structure occurs below 7 K. The ordered moments of Mn and Ce at 2 K are 3.32(4) μ B and 0.81(4)μ B, respectively. We find that CeMnAsO primarily falls into the category of a local-moment antiferromagnetic insulator in which the nearest-neighbor interaction (J 1) is dominant with J 2 < J 1/2 in the context of J 1 – J 2 – J c model. The spin reorientation transition driven by the coupling between Ce and the transition metal seems to be common to Mn, Fe, and Cr ions, but not to Co and Ni ions in the isostructural oxypnictides. As a result, a schematic illustration of magnetic structures in Mn and Ce sublattices in CeMnAsO is presented.« less

  13. A novel approach to training attention and gaze in ASD: A feasibility and efficacy pilot study.

    PubMed

    Chukoskie, Leanne; Westerfield, Marissa; Townsend, Jeanne

    2018-05-01

    In addition to the social, communicative and behavioral symptoms that define the disorder, individuals with ASD have difficulty re-orienting attention quickly and accurately. Similarly, fast re-orienting saccadic eye movements are also inaccurate and more variable in both endpoint and timing. Atypical gaze and attention are among the earliest symptoms observed in ASD. Disruption of these foundation skills critically affects the development of higher level cognitive and social behavior. We propose that interventions aimed at these early deficits that support social and cognitive skills will be broadly effective. We conducted a pilot clinical trial designed to demonstrate the feasibility and preliminary efficacy of using gaze-contingent video games for low-cost in-home training of attention and eye movement. Eight adolescents with ASD participated in an 8-week training, with pre-, mid- and post-testing of eye movement and attention control. Six of the eight adolescents completed the 8 weeks of training and all six showed improvement in attention (orienting, disengagement) and eye movement control or both. All game systems remained intact for the duration of training and all participants could use the system independently. We delivered a robust, low-cost, gaze-contingent game system for home use that, in our pilot training sample, improved the attention orienting and eye movement performance of adolescent participants in 8 weeks of training. We are currently conducting a clinical trial to replicate these results and to examine what, if any, aspects of training transfer to more real-world tasks. © 2017 Wiley Periodicals, Inc. Develop Neurobiol 78: 546-554, 2018. © 2017 Wiley Periodicals, Inc.

  14. Increased distractibility by task-irrelevant sound changes in abstinent alcoholics.

    PubMed

    Ahveninen, J; Jääskeläinen, I P; Pekkonen, E; Hallberg, A; Hietanen, M; Näätänen, R; Schröger, E; Sillanaukee, P

    2000-12-01

    Chronic alcoholism is accompanied by "frontal" neuropsychological deficits that include an inability to maintain focus of attention. This might be associated with pronounced involuntary attention shifting to task-irrelevant stimulus changes and, thereafter, an impaired reorienting to the relevant task. The neural abnormalities that underlie such deficits in alcoholics were explored with event-related potential (ERP) components that disclosed different phases of detection and orienting to stimulus changes. Twenty consecutive abstinent male alcoholics (DSM-IV) and 20 age-matched male controls (healthy social drinkers) were instructed to discriminate equiprobable 100 and 200 msec tones in a reaction-time task (RT) and to ignore occasional, either slight (7%) or wide (70%), frequency changes (hypothesized to increase RT) during an ERP measurement. In the alcoholics, we found pronounced distractibility, evidenced by a RT lag (p < 0.01) caused by deviants, that correlated (Spearman p = 0.5) with a significantly enhanced (p < 0.01) amplitude of mismatch negativity (MMN) to deviants. Significantly increased RT lag for trials subsequent to deviants (slight p < 0.001, wide p < 0.05) in the alcoholics suggested impaired reorienting to the relevant task. The MMN enhancement also predicted poorer hit rates in the alcoholics (Spearman p = 0.6-0.7). Both the MMN enhancement and pronounced distractibility correlated (Spearman p = 0.4) with an early onset of alcoholism. Attentional deficits in the abstinent alcoholics were indicated by the increased distractibility by irrelevant sound changes. The MMN enhancement suggested that this reflects impaired neural inhibition of involuntary attention shifting, being most pronounced in early-onset alcoholics.

  15. Collective dynamic dipole moment and orientation fluctuations, cooperative hydrogen bond relaxations, and their connections to dielectric relaxation in ionic acetamide deep eutectics: Microscopic insight from simulations

    NASA Astrophysics Data System (ADS)

    Das, Suman; Biswas, Ranjit; Mukherjee, Biswaroop

    2016-08-01

    The paper reports a detailed simulation study on collective reorientational relaxation, cooperative hydrogen bond (H-bond) fluctuations, and their connections to dielectric relaxation (DR) in deep eutectic solvents made of acetamide and three uni-univalent electrolytes, lithium nitrate (LiNO3), lithium bromide (LiBr), and lithium perchlorate (LiClO4). Because cooperative H-bond fluctuations and ion migration complicate the straightforward interpretation of measured DR timescales in terms of molecular dipolar rotations for these conducting media which support extensive intra- and inter-species H-bonding, one needs to separate out the individual components from the overall relaxation for examining the microscopic origin of various timescales. The present study does so and finds that reorientation of ion-complexed acetamide molecules generates relaxation timescales that are in sub-nanosecond to nanosecond range. This explains in molecular terms the nanosecond timescales reported by recent giga-Hertz DR measurements. Interestingly, the simulated survival timescale for the acetamide-Li+ complex has been found to be a few tens of nanosecond, suggesting such a cation-complexed species may be responsible for a similar timescale reported by mega-Hertz DR measurements of acetamide/potassium thiocyanate deep eutectics near room temperature. The issue of collective versus single particle relaxation is discussed, and jump waiting time distributions are determined. Dependence on anion-identity in each of the cases has been examined. In short, the present study demonstrates that assumption of nano-sized domain formation is not required for explaining the DR detected nanosecond and longer timescales in these media.

  16. Orbiting Sample Capture and Orientation Technologies for Potential Mars Sample Return

    NASA Astrophysics Data System (ADS)

    Younse, P.; Adajian, R.; Dolci, M.; Ohta, P.; Olds, E.; Lalla, K.; Strahle, J. W.

    2018-04-01

    Technologies applicable to a potential Mars Sample Return Orbiter for orbiting sample container capture and orientation are presented, as well as an integrated MArs CApture and ReOrientation for a potential NExt Mars Orbiter (MACARONE) concept.

  17. Fracture Toughness Evaluation of a Ni2MnGa Alloy Through Micro Indentation Under Magneto-Mechanical Loading

    NASA Astrophysics Data System (ADS)

    Goanţă, Viorel; Ciocanel, Constantin

    2017-12-01

    Ni2MnGa is a ferromagnetic alloy that exhibits the shape memory effect either induced by an externally applied magnetic field or mechanical stress. Due to the former, the alloy is commonly called magnetic shape memory alloy or MSMA. The microstructure of the MSMA consists of tetragonal martensite variants (three in the most general case) that are characterized by a magnetization vector which is aligned with the short side of the tetragonal unit cell. Exposing the MSMA to a magnetic field causes the magnetization vector to rotate and align with the external field, eventually leading to variant reorientation. The variant reorientation is observed macroscopically in the form of recoverable strain of up to 6% [1, 2]. As the magnetic field induced reorientation happens instantaneously [1, 3], MSMAs are suitable for fast actuation, sensing, or power harvesting applications. However, actuation applications are limited by the maximum actuation stress of the material that is about 3.5MPa at approximately 2 to 3% reorientation strain. During MSMA fatigue magneto-mechanical characterization studies [4, 5] it was observed that cracks nucleate and grow on the surface of material samples, after a relatively small number of cycles, leading to loss in material performance. This triggered the need for understanding the mechanisms that govern crack nucleation and growth in MSMAs, as well as the nature of the material, i.e. ductile or brittle. The experimental study reported in this paper was carried out to determine material's fracture toughness, the predominant crack growth directions, and the orientation of the cracks relative to the mechanical loading direction and to the material's microstructure. A fixture has been developed to allow Vickers micro indentation of 3mm by 3mm by 20mm Ni2MnGa samples exposed to different levels of magnetic field and/or mechanical stress. Using the measured characteristics of the impression generated during micro indentation, the lengths of propagated cracks, and appropriate equations (introduced in the paper), and the fracture toughness was evaluated as a function of the magneto-mechanical loading experienced by the material. The influence of the magneto-mechanical loading on the growth of already nucleated cracks has also been evaluated.

  18. Magnetostructural coupling, magnetic ordering, and cobalt spin reorientation in metallic P r0.5S r0.5Co O3 cobaltite

    NASA Astrophysics Data System (ADS)

    García-Muñoz, José Luis; Padilla-Pantoja, Jessica; Torrelles, Xavier; Blasco, Javier; Herrero-Martín, Javier; Bozzo, Bernat; Rodríguez-Velamazán, José A.

    2016-07-01

    In half-doped P r0.50A0.50Co O3 metallic perovskites, the spin-lattice coupling brings about distinct magnetostructural transitions for A =Ca and A =Sr at temperatures close to ˜100 K. However, the ground magnetic properties of P r0.50S r0.50Co O3 (PSCO) strongly differ from P r0.50C a0.50Co O3 ones, where a partial P r3 + to P r4 + valence shift and Co spin transition makes the system insulating below the transition. This paper investigates and describes the relationship between the I m m a →I 4 /m c m symmetry change [Padilla-Pantoja, García-Muñoz, Bozzo, Jirák, and Herrero-Martín, Inorg. Chem. 53, 12297 (2014)] and the original magnetic behavior of PSCO versus temperature and external magnetic fields. The FM1 and FM2 ferromagnetic phases, above and below the magnetostructural transition (TS 1˜120 K ) have been investigated. The FM2 phase of PSCO is composed of [100] FM domains, with magnetic symmetry I m'm'a (mx≠0 , mz=0 ). The magnetic space group of the FM1 phase is F m'm'm (with mx=my ). Neutron data analyses in combination with magnetometry and earlier reports results agrees with a reorientation of the magnetization axis by 45∘ within the a b plane across the transition, in which the system retains its metallic character. The presence below TS 1 of conjugated magnetic domains, both of F m'm'm symmetry but having perpendicular spin orientations along the diagonals in the x y plane of the tetragonal unit cell, is at the origin of the anomalies observed in the macroscopic magnetization. A relatively small field μ0H [⊥ z ] ≳30 mT is able to reorient the magnetization within the a b plane, whereas a higher field (μ0H [∥z ] ≳1.2 T at 2 K) is necessary to align the Co moments perpendicular to the a b plane. Such a spin reorientation, in which the orbital and spin components of the Co moment rotate joined by 45∘, was not observed previously in analogous cobaltites without praseodymium.

  19. Tidal-Rotational Dynamics of Solar System Worlds, from the Moon to Pluto

    NASA Astrophysics Data System (ADS)

    Keane, James Tuttle

    The spins of planetary bodies are not stagnant; they evolve in response to both external and internal forces. One way a planet's spin can change is through true polar wander. True polar wander is the reorientation of a planetary body with respect to its angular momentum vector, and occurs when mass is redistributed within the body, changing its principal axes of inertia. True polar wander can literally reshape a world, and has important implications for a variety of processes--from the long-term stability of polar volatiles in the permanently shadowed regions of airless worlds like the Moon and Mercury, to the global tectonic patterns of icy worlds like Pluto. In this dissertation, we investigate three specific instances of planetary true polar wander, and their associated consequences. In Chapter 2 we investigate the classic problem of the Moon's dynamical figure. By considering the effects of a fossil figure supported by an elastic lithosphere, and the contribution of impact basins to the figure, we find that the lunar figure is consistent with the Moon's lithosphere freezing in when the Moon was much closer to the Earth, on a low eccentricity synchronous orbit. The South Pole-Aitken impact basin is the single largest perturbation to the Moon's figure and resulted in tens of degrees of true polar wander after its formation. In Chapter 3 we continue our analyses of the lunar figure in light of the discovery of a lunar "volatile" paleopole, preserved in the distribution of hydrogen near the Moon's poles. We find that the formation and evolution of the Procellarum KREEP Terrain significantly altered the Moon's orientation, implying that some fraction of the Moon's polar volatiles are ancient--predating the geologic activity within the Procellarum region. In Chapter 4 we investigate how the formation of the giant, basin-filling glacier, Sputnik Planitia reoriented Pluto. This reorientation is recorded in both the present- day location of Sputnik Planitia (near the Pluto-Charon tidal axis), and the tectonic record of Pluto. This reorientation likely reflects a coupling between Pluto's volatile cycles and rotational dynamics, and may be active on other worlds with comparably large, mobile volatile reservoirs. Finally, in Chapter 5 we consider the broader context of these studies, and touch on future investigations of true polar wander on Mercury, Venus, Mars, Vesta, Ceres, and other worlds in our solar system.

  20. Collagen Matrix Remodeling in Stented Pulmonary Arteries after Transapical Heart Valve Replacement.

    PubMed

    Ghazanfari, Samaneh; Driessen-Mol, Anita; Hoerstrup, Simon P; Baaijens, Frank P T; Bouten, Carlijn V C

    2016-01-01

    The use of valved stents for minimally invasive replacement of semilunar heart valves is expected to change the extracellular matrix and mechanical function of the native artery and may thus impair long-term functionality of the implant. Here we investigate the impact of the stent on matrix remodeling of the pulmonary artery in a sheep model, focusing on matrix composition and collagen (re)orientation of the host tissue. Ovine native pulmonary arteries were harvested 8 (n = 2), 16 (n = 4) and 24 (n = 2) weeks after transapical implantation of self-expandable stented heart valves. Second harmonic generation (SHG) microscopy was used to assess the collagen (re)orientation of fresh tissue samples. The collagen and elastin content was quantified using biochemical assays. SHG microscopy revealed regional differences in collagen organization in all explants. In the adventitial layer of the arterial wall far distal to the stent (considered as the control tissue), we observed wavy collagen fibers oriented in the circumferential direction. These circumferential fibers were more straightened in the adventitial layer located behind the stent. On the luminal side of the wall behind the stent, collagen fibers were aligned along the stent struts and randomly oriented between the struts. Immediately distal to the stent, however, fibers on both the luminal and the adventitial side of the wall were oriented in the axial direction, demonstrating the stent impact on the collagen structure of surrounding arterial tissues. Collagen orientation patterns did not change with implantation time, and biochemical analyses showed no changes in the trend of collagen and elastin content with implantation time or location of the vascular wall. We hypothesize that the collagen fibers on the adventitial side of the arterial wall and behind the stent straighten in response to the arterial stretch caused by oversizing of the stent. However, the collagen organization on the luminal side suggests that stent-induced remodeling is dominated by contact guidance. © 2016 S. Karger AG, Basel.

  1. The effect of stress state on zirconium hydride reorientation

    NASA Astrophysics Data System (ADS)

    Cinbiz, Mahmut Nedim

    Prior to storage in a dry-cask facility, spent nuclear fuel must undergo a vacuum drying cycle during which the spent fuel rods are heated up to elevated temperatures of ≤ 400°C to remove moisture the canisters within the cask. As temperature increases during heating, some of the hydride particles within the cladding dissolve while the internal gas pressure in fuel rods increases generating multi-axial hoop and axial stresses in the closed-end thin-walled cladding tubes. As cool-down starts, the hydrogen in solid solution precipitates as hydride platelets, and if the multiaxial stresses are sufficiently large, the precipitating hydrides reorient from their initial circumferential orientation to radial orientation. Radial hydrides can severely embrittle the spent nuclear fuel cladding at low temperature in response to hoop stress loading. Because the cladding can experience a range of stress states during the thermo-mechanical treatment induced during vacuum drying, this study has investigated the effect of stress state on the process of hydride reorientation during controlled thermo-mechanical treatments utilizing the combination of in situ X-ray diffraction and novel mechanical testing analyzed by the combination of metallography and finite element analysis. The study used cold worked and stress relieved Zircaloy-4 sheet containing approx. 180 wt. ppm hydrogen as its material basis. The failure behavior of this material containing radial hydrides was also studied over a range of temperatures. Finally, samples from reactor-irradiated cladding tubes were examined by X-ray diffraction using synchrotron radiation. To reveal the stress state effect on hydride reorientation, the critical threshold stress to reorient hydrides was determined by designing novel mechanical test samples which produce a range of stress states from uniaxial to "near-equibiaxial" tension when a load is applied. The threshold stress was determined after thermo-mechanical treatments by correlating the finite element stress-state results with the spatial distribution of hydride microstructures observed within the optical micrographs for each sample. Experiments showed that the hydride reorientation was enhanced as the stress biaxiality increased. The threshold stress decreased from 150 MPa to 80 MPa when stress biaxiality ratio increased from uniaxial tension to near-equibiaxial tension. This behavior was also predicted by classical nucleation theory based on the Gibbs free energy of transformation being assisted by the far-field stress. An analysis of in situ X-ray diffraction data obtained during a thermo-mechanical cycle typical of vacuum drying showed a complex lattice-spacing behavior of the hydride phase during the dissolution and precipitation. The in-plane hydrides showed bilinear lattice expansion during heating with the intrinsic thermal expansion rate of the hydrides being observed only at elevated temperatures as they dissolve. For radial hydrides that precipitate during cooling under stress, the spacing of the close-packed {111} planes oriented normal to the maximum applied stress was permanently higher than the corresponding {111} plane spacing in the other directions. This behavior is believed to be a result of a complex stress state within the precipitating plate-like hydrides that induces a strain component within the hydrides normal to its "plate" face (i.e., the applied stress direction) that exceeds the lattice spacing strains in the other directions. During heat-up, the lattice spacing of these same "plate" planes actually contract due to the reversion of the stress state within the plate-like hydrides as they dissolve. The presence of radial hydrides and their connectivity with in-plane hydrides was shown to increase the ductile-to-brittle transition temperature during tensile testing. This behavior can be understood in terms of the role of radial hydrides in promoting the initiation of a long crack that subsequently propagates under fracture mechanics conditions. Finally, the d-spacing of irradiated Zircaloy-4 and M5 cladding tubes was measured at room temperature and compared to that of unirradiated samples.

  2. Dynamic heterogeneity in an orientational glass

    NASA Astrophysics Data System (ADS)

    Caballero, Nirvana B.; Zuriaga, Mariano; Tamarit, Josep Lluís; Serra, Pablo

    2017-11-01

    The family of compounds CBrnCl4-n has been proven helpful in unraveling microscopic mechanisms responsible for glassy behavior. Some of the family members show translational ordered phases with minimal disorder which appears to reveal glassy features, thus deserving special attention in the search for universal glass anomalies. In this work, we studied CBrCl3 dynamics by performing extensive molecular dynamics simulations. Molecules of this compound perform reorientational discrete jumps, where the atoms exchange equivalent positions among each other revealing a cage-orientational jump motion fully comparable to the cage-rototranslational jump motion in supercooled liquids. Correlation times were calculated from rotational autocorrelation functions showing good agreement with previous reported dielectric results. From mean waiting and persistence times calculated directly from trajectory results, we are able to explain which microscopic mechanisms lead to characteristic times associated with α- and β-relaxation times measured experimentally. We found that two nonequivalent groups of molecules have a longer characteristic time than the other two nonequivalent groups, both of them belonging to the asymmetric unit of the monoclinic (C2/c) lattice.

  3. Dynamic heterogeneity in an orientational glass.

    PubMed

    Caballero, Nirvana B; Zuriaga, Mariano; Tamarit, Josep Lluís; Serra, Pablo

    2017-11-14

    The family of compounds CBr n Cl 4-n has been proven helpful in unraveling microscopic mechanisms responsible for glassy behavior. Some of the family members show translational ordered phases with minimal disorder which appears to reveal glassy features, thus deserving special attention in the search for universal glass anomalies. In this work, we studied CBrCl 3 dynamics by performing extensive molecular dynamics simulations. Molecules of this compound perform reorientational discrete jumps, where the atoms exchange equivalent positions among each other revealing a cage-orientational jump motion fully comparable to the cage-rototranslational jump motion in supercooled liquids. Correlation times were calculated from rotational autocorrelation functions showing good agreement with previous reported dielectric results. From mean waiting and persistence times calculated directly from trajectory results, we are able to explain which microscopic mechanisms lead to characteristic times associated with α- and β-relaxation times measured experimentally. We found that two nonequivalent groups of molecules have a longer characteristic time than the other two nonequivalent groups, both of them belonging to the asymmetric unit of the monoclinic (C2/c) lattice.

  4. Slow secondary relaxation in a free-energy landscape model for relaxation in glass-forming liquids

    NASA Astrophysics Data System (ADS)

    Diezemann, Gregor; Mohanty, Udayan; Oppenheim, Irwin

    1999-02-01

    Within the framework of a free-energy landscape model for the relaxation in supercooled liquids the primary (α) relaxation is modeled by transitions among different free-energy minima. The secondary (β) relaxation then corresponds to intraminima relaxation. We consider a simple model for the reorientational motions of the molecules associated with both processes and calculate the dielectric susceptibility as well as the spin-lattice relaxation times. The parameters of the model can be chosen in a way that both quantities show a behavior similar to that observed in experimental studies on supercooled liquids. In particular we find that it is not possible to obtain a crossing of the time scales associated with α and β relaxation. In our model these processes always merge at high temperatures and the α process remains above the merging temperature. The relation to other models is discussed.

  5. Photo-induced refractive index and topographical surface gratings in functionalized nanocarbon solid film

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McGee, David J.; Ferrie, John; Plachy, Aljoscha

    2015-11-02

    We demonstrate that a single-walled carbon nanotube network noncovalently coupled with a pyrene-modified azo-benzene chromophore functions as a host matrix for a broad range of photo-orientation and photomechanical effects. The chromophore could be efficiently reoriented through repeated trans-cis-trans isomerization under linearly polarized 480 nm light, with Δn of 0.012 at 650 nm and fast characteristic rise-times of 0.12 s. Erasable phase diffraction gratings could also be written, with permanent surface relief gratings forming at sufficiently long irradiation times. In addition to demonstrating a mechanism for photo-manipulation of single-walled carbon nanotubes, these results show photo-orientation of chromophores in azo-functionalized single-walled carbon nanotube networks asmore » a path towards the photosensitive tuning of the electrostatic environment of the nanotube.« less

  6. Time-sequential observation of spindle and phragmoplast orientation in BY-2 cells with altered cortical actin microfilament patterning.

    PubMed

    Kojo, Kei H; Yasuhara, Hiroki; Hasezawa, Seiichiro

    2014-01-01

    Precise division plane determination is essential for plant development. At metaphase, a dense actin microfilament meshwork appears on both sides of the cell center, forming a characteristic cortical actin microfilament twin peak pattern in BY-2 cells. We previously reported a strong correlation between altered cortical actin microfilament patterning and an oblique mitotic spindle orientation, implying that these actin microfilament twin peaks play a role in the regulation of mitotic spindle orientation. In the present study, time-sequential observation was used to reveal the progression from oblique phragmoplast to oblique cell plate orientation in cells with altered cortical actin microfilament patterning. In contrast to cells with normal actin microfilament twin peaks, oblique phragmoplast reorientation was rarely observed in cells with altered cortical actin microfilament patterning. These results support the important roles of cortical actin microfilament patterning in division plane orientation.

  7. Time-sequential observation of spindle and phragmoplast orientation in BY-2 cells with altered cortical actin microfilament patterning.

    PubMed

    Kojo, Kei H; Yasuhara, Hiroki; Hasezawa, Seiichiro

    2014-06-18

    Precise division plane determination is essential for plant development. At metaphase, a dense actin microfilament meshwork appears on both sides of the cell center, forming a characteristic cortical actin microfilament twin peak pattern in BY-2 cells. We previously reported a strong correlation between altered cortical actin microfilament patterning and an oblique mitotic spindle orientation, implying that these actin microfilament twin peaks play a role in the regulation of mitotic spindle orientation. In the present study, time-sequential observation was used to reveal the progression from oblique phragmoplast to oblique cell plate orientation in cells with altered cortical actin microfilament patterning. In contrast to cells with normal actin microfilament twin peaks, oblique phragmoplast reorientation was rarely observed in cells with altered cortical actin microfilament patterning. These results support the important roles of cortical actin microfilament patterning in division plane orientation.

  8. Characterization of a gel in the cell wall to elucidate the paradoxical shrinkage of tension wood.

    PubMed

    Clair, Bruno; Gril, Joseph; Di Renzo, Francesco; Yamamoto, Hiroyuki; Quignard, Françoise

    2008-02-01

    Wood behavior is characterized by high sensibility to humidity and strongly anisotropic properties. The drying shrinkage along the fibers, usually small due to the reinforcing action of cellulosic microfibrils, is surprisingly high in the so-called tension wood, produced by trees to respond to strong reorientation requirements. In this study, nitrogen adsorption-desorption isotherms of supercritically dried tension wood and normal wood show that the tension wood cell wall has a gel-like structure characterized by a pore surface more than 30 times higher than that in normal wood. Syneresis of the tension wood gel explains its paradoxical drying shrinkage. This result could help to reduce technological problems during drying. Potential applications in biomechanics and biomimetics are worth investigating, considering that, in living trees, tension wood produces tensile growth stresses 10 times higher than that of normal wood.

  9. Acousto-Optical Evaluation Of Fiber Size In Wood Pulp

    NASA Astrophysics Data System (ADS)

    Dion, J. L.; Garceau, J. J.; Morissette, J. C.

    1986-10-01

    In the pulp and paper industry, the problem of regular and fast evaluation of wood fiber characteristics such as length and specific area is an important one. With this in view, we have been studying an acousto-optical technique based on the acoustic agglomeration of fibers in a water suspension, where a stationary ultrasonic field is created at about 150 kHz. Under the influence of radiation forces, fibers re-orient themselves parallel to the nodal planes of acoustic pressure, and regroup or agglomerate in these planes in different characteristic times. These are mesured by means of the light scattered at small angles. We have found that these times depend on the size distribution of fibers, particularly length. We present results obtained with an assortment of fiber types, under various experimental conditions which indicate eventual applications in the automatic control of pulp production.

  10. Coupling between overall rotational diffusion and domain motions in proteins and its effect on dielectric spectra.

    PubMed

    Ryabov, Yaroslav

    2015-09-01

    In this work, we formulate a closed-form solution of the model of a semirigid molecule for the case of fluctuating and reorienting molecular electric dipole moment. We illustrate with numeric calculations the impact of protein domain motions on dielectric spectra using the example of the 128 kDa protein dimer of Enzyme I. We demonstrate that the most drastic effect occurs for situations when the characteristic time of protein domain dynamics is comparable to the time of overall molecular rotational diffusion. We suggest that protein domain motions could be a possible explanation for the high-frequency contribution that accompanies the major relaxation dispersion peak in the dielectric spectra of protein aqueous solutions. We propose that the presented computational methodology could be used for the simultaneous analysis of dielectric spectroscopy and nuclear magnetic resonance data. Proteins 2015; 83:1571-1581. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  11. Mirjana Dimitrievska | NREL

    Science.gov Websites

    understanding the structure-dependent vibrational properties and reorientational behavior of different alkali Sad, Serbia Featured Publications M. Dimitrievska et al., "Structure-dependent vibrational : Structure and luminescence," J. Phys. Chem. C 120(33), 18887-18894 (2016). DOI: http://dx.doi.org

  12. Effect of aging on the piezoelectric properties of sol-gel derived lead-free BCZT ceramics

    NASA Astrophysics Data System (ADS)

    Chandrakala, E.; Hazra, Binoy Krishna; Praveen, J. Paul; Das, Dibakar

    2018-04-01

    Aging is well observed in piezoelectric materials and plays a major role in determining the sustainabilityand performance issues of the piezoelectric based devices. Aging behavior is usually defined as the spontaneous decay of the piezoelectric properties with time. In this present study, the effect of aging on the piezoelectric properties of sol-gel derived lead-free BCZT ceramics has been investigated. During the aging process, the ferroelectric hysteresis loop was shifted along the field axis. The results revealed that the piezoelectric and dielectric properties were rapidly decreased linearly with increasing aging time and become stable with further increase in aging time. Piezoelectric (d33, g33 &kp) and dielectric properties (ɛr) were decreased approximately by 18% after 70 days. This could be due to the gradual stabilization of the ferroelectric domain structurewhich originates from the reorientation of the local defect dipoles and the migration of free oxygen vacancies towards the grain boundaries.

  13. Gravitropism: interaction of sensitivity modulation and effector redistribution

    NASA Technical Reports Server (NTRS)

    Evans, M. L.

    1991-01-01

    Our increasing capabilities for quantitative hormone analysis and automated high resolution growth studies have allowed a reassessment of the classical Cholodny-Went hypothesis of gravitropism. According to this hypothesis, gravity induces redistribution of auxin toward the lower side of the organ and this causes the growth asymmetry that leads to reorientation. Arguments against the Cholodny-Went hypothesis that were based primarily on concerns over the timing and magnitude of the development of hormone asymmetry are countered by recent evidence that such asymmetry develops early and is sufficiently large to account for curvature. Thus, it appears that the Cholodny-Went hypothesis is fundamentally valid. However, recent comparative studies of the kinetics of curvature and the timing of the development of hormone asymmetry indicate that this hypothesis alone cannot account for the intricacies of the gravitropic response. It appears that time-dependent gravity-induced changes in hormone sensitivity as well as changes in sensitivity of the gravity receptor play important roles in the response.

  14. Gravitropism: Interaction of Sensitivity Modulation and Effector Redistribution 1

    PubMed Central

    Evans, Michael L.

    1991-01-01

    Our increasing capabilities for quantitative hormone analysis and automated high resolution growth studies have allowed a reassessment of the classical Cholodny-Went hypothesis of gravitropism. According to this hypothesis, gravity induces redistribution of auxin toward the lower side of the organ and this causes the growth asymmetry that leads to reorientation. Arguments against the Cholodny-Went hypothesis that were based primarily on concerns over the timing and magnitude of the development of hormone asymmetry are countered by recent evidence that such asymmetry develops early and is sufficiently large to account for curvature. Thus, it appears that the Cholodny-Went hypothesis is fundamentally valid. However, recent comparative studies of the kinetics of curvature and the timing of the development of hormone asymmetry indicate that this hypothesis alone cannot account for the intricacies of the gravitropic response. It appears that time-dependent gravity-induced changes in hormone sensitivity as well as changes in sensitivity of the gravity receptor play important roles in the response. PMID:11537485

  15. Near-infrared sensitive photorefractive device using polymer dispersed liquid crystal and BSO:Ru hybrid structure.

    PubMed

    Liu, Ren Chung; Marinova, Vera; Lin, Shiuan Huei; Chen, Ming-Syuan; Lin, Yi-Hsin; Hsu, Ken Yuh

    2014-06-01

    A near-infrared sensitive hybrid device, based on a Ru-doped BSO photorefractive substrate and polymer dispersed liquid crystal (PDLC) layer, is reported. It is found that the photoexcited charge carriers generated in the BSO:Ru substrate create an optically induced space charge field, sufficient to penetrate into the PDLC layer and to re-orient the LC molecules inside the droplets. Beam-coupling measurements at the Bragg regime are performed showing prospective amplification values and high spatial resolution. The proposed structure does not require indium tin oxide (ITO) contacts and alignment layers. Such a device allows all the processes to be controlled by light, thus opening further potential for real-time image processing at the near-infrared range.

  16. European Union vaccine research--an overview.

    PubMed

    Sautter, Jürgen; Olesen, Ole F; Bray, Jeremy; Draghia-Akli, Ruxandra

    2011-09-09

    Recent developments in vaccine research provide new momentum for an important area in health innovation. Particularly interesting are novel DNA vaccine approaches, many of which are already under clinical investigation. The Framework Programmes of the European Union play an important role in supporting collaborative efforts in vaccine research to develop new and better vaccines and bring them to the market. With a timely strategic reorientation towards a sustainable investment in innovation, the current seventh Framework Programme will help to bring large industry and small and medium-sized enterprises (SME) on board and foster partnership between stakeholders. As the first human DNA vaccines progresses through the development pipeline, more and more questions revolve around licensing and regulation and appropriate guidelines are being developed. Copyright © 2011. Published by Elsevier Ltd.

  17. Electric field control of magnon-induced magnetization dynamics in multiferroics.

    PubMed

    Risinggård, Vetle; Kulagina, Iryna; Linder, Jacob

    2016-08-24

    We consider theoretically the effect of an inhomogeneous magnetoelectric coupling on the magnon-induced dynamics of a ferromagnet. The magnon-mediated magnetoelectric torque affects both the homogeneous magnetization and magnon-driven domain wall motion. In the domains, we predict a reorientation of the magnetization, controllable by the applied electric field, which is almost an order of magnitude larger than that observed in other physical systems via the same mechanism. The applied electric field can also be used to tune the domain wall speed and direction of motion in a linear fashion, producing domain wall velocities several times the zero field velocity. These results show that multiferroic systems offer a promising arena to achieve low-dissipation magnetization rotation and domain wall motion by exciting spin-waves.

  18. Consistent visualizations of changing knowledge

    PubMed Central

    Tipney, Hannah J.; Schuyler, Ronald P.; Hunter, Lawrence

    2009-01-01

    Networks are increasingly used in biology to represent complex data in uncomplicated symbolic form. However, as biological knowledge is continually evolving, so must those networks representing this knowledge. Capturing and presenting this type of knowledge change over time is particularly challenging due to the intimate manner in which researchers customize those networks they come into contact with. The effective visualization of this knowledge is important as it creates insight into complex systems and stimulates hypothesis generation and biological discovery. Here we highlight how the retention of user customizations, and the collection and visualization of knowledge associated provenance supports effective and productive network exploration. We also present an extension of the Hanalyzer system, ReOrient, which supports network exploration and analysis in the presence of knowledge change. PMID:21347184

  19. Voltage control of magnetic monopoles in artificial spin ice

    NASA Astrophysics Data System (ADS)

    Chavez, Andres C.; Barra, Anthony; Carman, Gregory P.

    2018-06-01

    Current research on artificial spin ice (ASI) systems has revealed unique hysteretic memory effects and mobile quasi-particle monopoles controlled by externally applied magnetic fields. Here, we numerically demonstrate a strain-mediated multiferroic approach to locally control the ASI monopoles. The magnetization of individual lattice elements is controlled by applying voltage pulses to the piezoelectric layer resulting in strain-induced magnetic precession timed for 180° reorientation. The model demonstrates localized voltage control to move the magnetic monopoles across lattice sites, in CoFeB, Ni, and FeGa based ASI’s. The switching is achieved at frequencies near ferromagnetic resonance and requires energies below 620 aJ. The results demonstrate that ASI monopoles can be efficiently and locally controlled with a strain-mediated multiferroic approach.

  20. ASSESSING ECOLOGICAL RISKS AT LARGE SPATIAL SCALES

    EPA Science Inventory

    The history of environmental management and regulation in the United States has been one of initial focus on localized, end-of-the-pipe problems to increasing attention to multi-scalar, multi-stressor, and multi- resource issues. Concomitant with this reorientation is the need fo...

  1. Local Government Training.

    ERIC Educational Resources Information Center

    United Nations, New York, NY. Dept. of Economic and Social Affairs.

    In developing nations, the decentralization of responsibilities relating to agriculture, irrigation, public health and sanitation, and small and large industry necessitates the training in public affairs for local government officials. They need training in policy forming and administrative roles as well as a reorientation of attitudes toward the…

  2. HET2 Overview

    NASA Technical Reports Server (NTRS)

    Fong, Terrence W.; Bualat, Maria Gabriele; Diftler, Myron A.

    2015-01-01

    2015 mid-year review charts of the Human Exploration Telerobotics 2 project that describe the Astrobee free-flying robot and the Robonaut 2 humanoid robot. A planned replacement for Synchronized Position Hold, Engage, Reorient, Experimental Satellite (SPHERES), which is currently in use in the International Space Station (ISS).

  3. Leveraging Information Technology. Track III: Organizational Issues.

    ERIC Educational Resources Information Center

    CAUSE, Boulder, CO.

    Seven papers from the 1987 CAUSE conference's Track III, Organizational Issues, are presented. They include: "Learning Resources and Technologies: A Unified Organizational Reorientation to Administering Educational Support Services" (Morrell D. Boone); "IRM: A Short-Lived Concept?" (James I. Penrod and Michael G. Dolence);…

  4. Systemic and Global Learning.

    ERIC Educational Resources Information Center

    Small, Michele Geslin

    In a rapidly changing world, schools need to reorient their curricula to ensure adequate preparation of children for the future. Among the fundamental changes affecting society are the diversification of lifestyles, the development of genetic engineering, trends toward automation, and the information explosion. The educational crisis reflects…

  5. Removing Preconceptions with a "Learning Cycle."

    ERIC Educational Resources Information Center

    Gang, Su

    1995-01-01

    Describes a teaching experiment that uses the Learning Cycle to achieve the reorientation of physics' students conceptual frameworks away from commonsense perspectives toward scientifically rigorous outlooks. Uses Archimedes' principle as the content topic while using the Learning Cycle to remove students' nonscientific preconceptions. (JRH)

  6. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018572 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  7. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018486 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  8. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018466 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  9. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018383 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  10. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018390 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  11. SPHERES Zero Robotics

    NASA Image and Video Library

    2014-06-24

    ISS040-E-018417 (24 June 2014) --- Russian cosmonaut Oleg Artemyev (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session of the Synchronized Position Hold, Engage, Reorient, Experimental Satellites Zero Robotics (SPHERES ZR) program in the Kibo laboratory of the International Space Station.

  12. Neural correlates of the spatial and expectancy components of endogenous and stimulus-driven orienting of attention in the Posner task.

    PubMed

    Doricchi, Fabrizio; Macci, Enrica; Silvetti, Massimo; Macaluso, Emiliano

    2010-07-01

    Voluntary orienting of visual attention is conventionally measured in tasks with predictive central cues followed by frequent valid targets at the cued location and by infrequent invalid targets at the uncued location. This implies that invalid targets entail both spatial reorienting of attention and breaching of the expected spatial congruency between cues and targets. Here, we used event-related functional magnetic resonance imaging (fMRI) to separate the neural correlates of the spatial and expectancy components of both endogenous orienting and stimulus-driven reorienting of attention. We found that during endogenous orienting with predictive cues, there was a significant deactivation of the right Temporal-Parietal Junction (TPJ). We also discovered that the lack of an equivalent deactivation with nonpredictive cues was matched to drop in attentional costs and preservation of attentional benefits. The right TPJ showed equivalent responses to invalid targets following predictive and nonpredictive cues. On the contrary, infrequent-unexpected invalid targets following predictive cues specifically activated the right Middle and Inferior Frontal Gyrus (MFG-IFG). Additional comparisons with spatially neutral trials demonstrated that, independently of cue predictiveness, valid targets activate the left TPJ, whereas invalid targets activate both the left and right TPJs. These findings show that the selective right TPJ activation that is found in the comparison between invalid and valid trials results from the reciprocal cancelling of the different activations that in the left TPJ are related to the processing of valid and invalid targets. We propose that left and right TPJs provide "matching and mismatching to attentional template" signals. These signals enable reorienting of attention and play a crucial role in the updating of the statistical contingency between cues and targets.

  13. Revised Pacific-Antarctic plate motions and geophysics of the Menard Fracture Zone

    NASA Astrophysics Data System (ADS)

    Croon, Marcel B.; Cande, Steven C.; Stock, Joann M.

    2008-07-01

    A reconnaissance survey of multibeam bathymetry and magnetic anomaly data of the Menard Fracture Zone allows for significant refinement of plate motion history of the South Pacific over the last 44 million years. The right-stepping Menard Fracture Zone developed at the northern end of the Pacific-Antarctic Ridge within a propagating rift system that generated the Hudson microplate and formed the conjugate Henry and Hudson Troughs as a response to a major plate reorganization ˜45 million years ago. Two splays, originally about 30 to 35 km apart, narrowed gradually to a corridor of 5 to 10 km width, while lineation azimuths experienced an 8° counterclockwise reorientation owing to changes in spreading direction between chrons C13o and C6C (33 to 24 million years ago). We use the improved Pacific-Antarctic plate motions to analyze the development of the southwest end of the Pacific-Antarctic Ridge. Owing to a 45° counterclockwise reorientation between chrons C27 and C20 (61 to 44 million years ago) this section of the ridge became a long transform fault connected to the Macquarie Triple Junction. Following a clockwise change starting around chron C13o (33 million years ago), the transform fault opened. A counterclockwise change starting around chron C10y (28 millions years ago) again led to a long transform fault between chrons C6C and C5y (24 to 10 million years ago). A second period of clockwise reorientation starting around chron C5y (10 million years ago) put the transform fault into extension, forming an array of 15 en echelon transform faults and short linking spreading centers.

  14. The Effect of Lens Sphere and Cylinder Power on Residual Astigmatism and Its Resolution After Toric Intraocular Lens Implantation.

    PubMed

    Berdahl, John P; Hardten, David R; Kramer, Brent A; Potvin, Richard

    2017-03-01

    To analyze correlations between residual refractive cylinder (and its correction through lens reorientation) with the sphere and cylinder power of the toric intraocular lens (IOL) implanted. An online toric back-calculator (www.astigmatismfix.com) allows users to input toric IOL planning data, along with postoperative IOL orientation and refractive results; these data are used to determine the optimal orientation of the IOL to reduce refractive astigmatism. This was a retrospective data analysis; aggregate historical data were extracted from this calculator to investigate the relationship between residual refractive astigmatism and IOL cylinder and sphere power. A total of 12,812 records, 4,619 of which included IOL sphere power, were available for analysis. There was no significant effect of sphere power on residual refractive astigmatism (P = .25), but lower IOL cylinder powers were associated with significantly lower residual refractive astigmatism (P < .05). The difference between the intended and ideal orientation was higher in the lower IOL cylinder power groups (P < .01). Overcorrection of astigmatism was significantly more likely with higher IOL cylinder power (P < .01), but not with sphere power (P = .33). Reorientation to correct residual refractive cylinder to less than 0.50 diopters (D) was more successful with IOL cylinder powers of 1.50 D or less (P < .01); IOL sphere power had no apparent effect. There were significant effects of IOL cylinder power on residual refractive astigmatism, the difference between intended and ideal orientation, the likelihood of overcorrection, and the likelihood of astigmatism reduction with lens reorientation. IOL sphere power appeared to have no such effects. [J Refract Surg. 2017;33(3):157-162.]. Copyright 2017, SLACK Incorporated.

  15. The role of the right temporoparietal junction in attention and social interaction as revealed by ALE meta-analysis

    PubMed Central

    Rottschy, C.; Oberwelland, E.; Bzdok, D.; Fox, P. T.; Eickhoff, S. B.; Fink, G. R.; Konrad, K.

    2016-01-01

    The right temporoparietal junction (rTPJ) is frequently associated with different capacities that to shift attention to unexpected stimuli (reorienting of attention) and to understand others’ (false) mental state [theory of mind (ToM), typically represented by false belief tasks]. Competing hypotheses either suggest the rTPJ representing a unitary region involved in separate cognitive functions or consisting of subregions subserving distinct processes. We conducted activation likelihood estimation (ALE) meta-analyses to test these hypotheses. A conjunction analysis across ALE meta-analyses delineating regions consistently recruited by reorienting of attention and false belief studies revealed the anterior rTPJ, suggesting an overarching role of this specific region. Moreover, the anatomical difference analysis unravelled the posterior rTPJ as higher converging in false belief compared with reorienting of attention tasks. This supports the concept of an exclusive role of the posterior rTPJ in the social domain. These results were complemented by meta-analytic connectivity mapping (MACM) and resting-state functional connectivity (RSFC) analysis to investigate whole-brain connectivity patterns in task-constrained and task-free brain states. This allowed for detailing the functional separation of the anterior and posterior rTPJ. The combination of MACM and RSFC mapping showed that the posterior rTPJ has connectivity patterns with typical ToM regions, whereas the anterior part of rTPJ co-activates with the attentional network. Taken together, our data suggest that rTPJ contains two functionally fractionated subregions: while posterior rTPJ seems exclusively involved in the social domain, anterior rTPJ is involved in both, attention and ToM, conceivably indicating an attentional shifting role of this region. PMID:24915964

  16. Practicalities and challenges in re-orienting the health system in Zambia for treating chronic conditions.

    PubMed

    Aantjes, Carolien J; Quinlan, Tim K C; Bunders, Joske F G

    2014-07-08

    The rapid evolution in disease burdens in low- and middle income countries is forcing policy makers to re-orient their health system towards a system which has the capability to simultaneously address infectious and non-communicable diseases. This paper draws on two different but overlapping studies which examined how actors in the Zambian health system are re-directing their policies, strategies and service structures to include the provision of health care for people with chronic conditions. Study methods in both studies included semi-structured interviews with government health officials at national level, and governmental and non-governmental health practitioners operating from community-, primary health care to hospital facility level. Focus group discussions were conducted with staff, stakeholders and caregivers of programmes providing care and support at community- and household levels. Study settings included urban and rural sites. A series of adaptations transformed the HIV programme from an emergency response into the first large chronic care programme in the country. There are clear indications that the Zambian government is intending to expand this reach to patients with non-communicable diseases. Challenges to do this effectively include a lack of proper NCD prevalence data for planning, a concentration of technology and skills to detect and treat NCDs at secondary and tertiary levels in the health system and limited interest by donor agencies to support this transition. The reorientation of Zambia's health system is in full swing and uses the foundation of a decentralised health system and presence of local models for HIV chronic care which actively involve community partners, patients and their families. There are early warning signs which could cause this transition to stall, one of which is the financial capability to resource this process.

  17. Spatiotemporal relationships between growth and microtubule orientation as revealed in living root cells of Arabidopsis thaliana transformed with green-fluorescent-protein gene construct GFP-MBD

    NASA Technical Reports Server (NTRS)

    Granger, C. L.; Cyr, R. J.

    2001-01-01

    Arabidopsis thaliana plants were transformed with GFP-MBD (J. Marc et al., Plant Cell 10: 1927-1939, 1998) under the control of a constitutive (35S) or copper-inducible promoter. GFP-specific fluorescence distributions, levels, and persistence were determined and found to vary with age, tissue type, transgenic line, and individual plant. With the exception of an increased frequency of abnormal roots of 35S GFP-MBD plants grown on kanamycin-containing media, expression of GFP-MBD does not appear to affect plant phenotype. The number of leaves, branches, bolts, and siliques as well as overall height, leaf size, and seed set are similar between wild-type and transgenic plants as is the rate of root growth. Thus, we conclude that the transgenic plants can serve as a living model system in which the dynamic behavior of microtubules can be visualized. Confocal microscopy was used to simultaneously monitor growth and microtubule behavior within individual cells as they passed through the elongation zone of the Arabidopsis root. Generally, microtubules reoriented from transverse to oblique or longitudinal orientations as growth declined. Microtubule reorientation initiated at the ends of the cell did not necessarily occur simultaneously in adjacent neighboring cells and did not involve complete disintegration and repolymerization of microtubule arrays. Although growth rates correlated with microtubule reorientation, the two processes were not tightly coupled in terms of their temporal relationships, suggesting that other factor(s) may be involved in regulating both events. Additionally, microtubule orientation was more defined in cells whose growth was accelerating and less stringent in cells whose growth was decelerating, indicating that microtubule-orienting factor(s) may be sensitive to growth acceleration, rather than growth per se.

  18. Magnetic behavior of R2Fe14B hydrides (R = Gd, Tb, Dy, Ho and Er)

    NASA Astrophysics Data System (ADS)

    Zhang, L. Y.; Pourarian, F.; Wallace, W. E.

    1988-01-01

    R 2Fe 14B systems, with R = Gd, Tb, By, HoandEr were hydrogenated to the composition R 2Fe 14BH x where x ranges from 3.7 to 5.4. The pressure-composition isotherms (PCIs) of the hydrides showed only a solid solution behavior. No plateau pressure region was observed between room temperature and 300° C and at pressures down to 10 -2 atm. The absorbed hydrogen leads to an increase of 2.6 to 3.4% in unit cell volume, without a change in crystal structure. Magnetic characteristics of the present compounds were investigated over the temperature range 4.2 to 1100 K and at applied field up to 20 kOe. Saturation magnetization, Ms, and magnetic ordering temperature, Tc, were enhanced upon hydrogenation. Tc, is found to be dependent on the hydriding composition. Hydrogen induces a spin-reorientation effect (SR) in Gd- and Dy-containing compounds, while it has a marked influence in raising the spin-reorientation temperature, TSR, in the Er 2Fe 14B compound. The hydride involving Tb appears to remain uniaxial to the lowest temperature studied. In all cases the anisotropy fields, HA/' were significally reduced by hydrogen absorption. These varied magnetic behaviors can be ascribed to the effects: (1) variations in the interatomic distances, (2) strengthening the 3d-3d and weakening the 4f-3d exchange interactions and (3) the interstitial site occupations of hydrogen in the lattice. The spin-reorientation phenomena observed for Gd 2Fe 14BH x suggest that there is competition among the 6 Fe sublattices in regard to the sign and temperature coefficient of anisotropy.

  19. Effect of flexibility on the growth of concentration fluctuations in a suspension of sedimenting fibers: Particle simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manikantan, Harishankar; Saintillan, David

    2016-01-15

    Three-dimensional numerical simulations are performed to study the stability of a sedimenting suspension of weakly flexible fibers. It is well known that a suspension of rigid rods sedimenting under gravity at low Reynolds number is unstable to concentration fluctuations owing to hydrodynamic interactions. Flexible fibers, however, reorient while settling and even weak flexibility can alter their collective dynamics. In our recent work [Manikantan et al., “The instability of a sedimenting suspension of weakly flexible fibres,” J. Fluid Mech. 756, 935–964 (2014)], we developed a mean-field theory to predict the linear stability of such a system. Here, we verify these predictionsmore » using accurate and efficient particle simulations based on a slender-body model. We also demonstrate the mechanisms by which flexibility-induced reorientation alters suspension microstructure, and through it, its stability. Specifically, we first show that the anisotropy of the base state in the case of a suspension of flexible fibers has a destabilizing effect compared to a suspension of rigid rods. Second, a conflicting effect of flexibility is also shown to suppress particle clustering and slow down the growth of the instability. The relative magnitude of filament flexibility and rotational Brownian motion dictates which effect dominates, and our simulations qualitatively follow theoretically predicted trends. The mechanism for either effects is tied to the flexibility-induced reorientation of particles, which we illustrate using velocity and orientation statistics from our simulations. Finally, we also show that, in the case of an initially homogeneous and isotropic suspension, flexibility always acts to suppress the growth of the instability.« less

  20. Seamless Warping of Diffusion Tensor Fields

    PubMed Central

    Hao, Xuejun; Bansal, Ravi; Plessen, Kerstin J.; Peterson, Bradley S.

    2008-01-01

    To warp diffusion tensor fields accurately, tensors must be reoriented in the space to which the tensors are warped based on both the local deformation field and the orientation of the underlying fibers in the original image. Existing algorithms for warping tensors typically use forward mapping deformations in an attempt to ensure that the local deformations in the warped image remains true to the orientation of the underlying fibers; forward mapping, however, can also create “seams” or gaps and consequently artifacts in the warped image by failing to define accurately the voxels in the template space where the magnitude of the deformation is large (e.g., |Jacobian| > 1). Backward mapping, in contrast, defines voxels in the template space by mapping them back to locations in the original imaging space. Backward mapping allows every voxel in the template space to be defined without the creation of seams, including voxels in which the deformation is extensive. Backward mapping, however, cannot reorient tensors in the template space because information about the directional orientation of fiber tracts is contained in the original, unwarped imaging space only, and backward mapping alone cannot transfer that information to the template space. To combine the advantages of forward and backward mapping, we propose a novel method for the spatial normalization of diffusion tensor (DT) fields that uses a bijection (a bidirectional mapping with one-to-one correspondences between image spaces) to warp DT datasets seamlessly from one imaging space to another. Once the bijection has been achieved and tensors have been correctly relocated to the template space, we can appropriately reorient tensors in the template space using a warping method based on Procrustean estimation. PMID:18334425

  1. Inferior parietal and right frontal contributions to trial-by-trial adaptations of attention to memory.

    PubMed

    Kizilirmak, Jasmin M; Rösler, Frank; Bien, Siegfried; Khader, Patrick H

    2015-07-21

    The attention to memory theory (AtoM) proposes that the same brain regions might be involved in selective processing of perceived stimuli (selective attention) and memory representations (selective retrieval). Although this idea is compelling, given consistently found neural overlap between perceiving and remembering stimuli, recent comparisons brought evidence for overlap as well as considerable differences. Here, we present a paradigm that enables the investigation of the AtoM hypothesis from a novel perspective to gain further insight into the neural resources involved in AtoM. Selective attention in perception is often investigated as a control process that shows lingering effects on immediately following trials. Here, we employed a paradigm capable of modulating selective retrieval in a similarly dynamic manner as in such selective-attention paradigms by inducing trial-to-trial shifts between relevant and irrelevant memory representations as well as changes of the width of the internal focus on memory. We found evidence for an involvement of bilateral inferior parietal lobe and right inferior frontal gyrus in reorienting the attentional focus on previously accessed memory representations. Moreover, we could dissociate the right inferior from the parietal activation in separate contrasts, suggesting that the right inferior frontal gyrus plays a role in facilitating attentional reorienting to memory representations when competing representations have been activated in the preceding trial, potentially by resolving this competition. Our results support the AtoM theory, i.e. that ventral frontal and parietal regions are involved in automatic attentional reorienting in memory, and highlight the importance of further investigations of the overlap and differences between regions involved in internal (memory) and external (perceptual) attentional selection. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Dynamics of Fos-Jun-NFAT1 complexes

    PubMed Central

    Ramirez-Carrozzi, Vladimir R.; Kerppola, Tom K.

    2001-01-01

    Transcription initiation in eukaryotes is controlled by nucleoprotein complexes formed through cooperative interactions among multiple transcription regulatory proteins. These complexes may be assembled via stochastic collisions or defined pathways. We investigated the dynamics of Fos-Jun-NFAT1 complexes by using a multicolor fluorescence resonance energy transfer assay. Fos-Jun heterodimers can bind to AP-1 sites in two opposite orientations, only one of which is populated in mature Fos-Jun-NFAT1 complexes. We studied the reversal of Fos-Jun binding orientation in response to NFAT1 by measuring the efficiencies of energy transfer from donor fluorophores linked to opposite ends of an oligonucleotide to an acceptor fluorophore linked to one subunit of the heterodimer. The reorientation of Fos-Jun by NFAT1 was not inhibited by competitor oligonucleotides or heterodimers. The rate of Fos-Jun reorientation was faster than the rate of heterodimer dissociation at some binding sites. The facilitated reorientation of Fos-Jun heterodimers therefore can enhance the efficiency of Fos-Jun-NFAT1 complex formation. We also examined the influence of the preferred orientation of Fos-Jun binding on the stability and transcriptional activity of Fos-Jun-NFAT1 complexes. Complexes formed at sites where Fos-Jun favored the same binding orientation in the presence and absence of NFAT1 exhibited an 8-fold slower dissociation rate than complexes formed at sites where Fos-Jun favored the opposite binding orientation. Fos-Jun-NFAT1 complexes also exhibited greater transcription activation at promoter elements that favored the same orientation of Fos-Jun binding in the presence and absence of NFAT1. Thus, the orientation of heterodimer binding can influence both the dynamics and promoter selectivity of multiprotein transcription regulatory complexes. PMID:11320240

  3. Dynamics of Fos-Jun-NFAT1 complexes.

    PubMed

    Ramirez-Carrozzi, V R; Kerppola, T K

    2001-04-24

    Transcription initiation in eukaryotes is controlled by nucleoprotein complexes formed through cooperative interactions among multiple transcription regulatory proteins. These complexes may be assembled via stochastic collisions or defined pathways. We investigated the dynamics of Fos-Jun-NFAT1 complexes by using a multicolor fluorescence resonance energy transfer assay. Fos-Jun heterodimers can bind to AP-1 sites in two opposite orientations, only one of which is populated in mature Fos-Jun-NFAT1 complexes. We studied the reversal of Fos-Jun binding orientation in response to NFAT1 by measuring the efficiencies of energy transfer from donor fluorophores linked to opposite ends of an oligonucleotide to an acceptor fluorophore linked to one subunit of the heterodimer. The reorientation of Fos-Jun by NFAT1 was not inhibited by competitor oligonucleotides or heterodimers. The rate of Fos-Jun reorientation was faster than the rate of heterodimer dissociation at some binding sites. The facilitated reorientation of Fos-Jun heterodimers therefore can enhance the efficiency of Fos-Jun-NFAT1 complex formation. We also examined the influence of the preferred orientation of Fos-Jun binding on the stability and transcriptional activity of Fos-Jun-NFAT1 complexes. Complexes formed at sites where Fos-Jun favored the same binding orientation in the presence and absence of NFAT1 exhibited an 8-fold slower dissociation rate than complexes formed at sites where Fos-Jun favored the opposite binding orientation. Fos-Jun-NFAT1 complexes also exhibited greater transcription activation at promoter elements that favored the same orientation of Fos-Jun binding in the presence and absence of NFAT1. Thus, the orientation of heterodimer binding can influence both the dynamics and promoter selectivity of multiprotein transcription regulatory complexes.

  4. Building health promotion capacity in a primary health care workforce in the Northern Territory: some lessons from practice.

    PubMed

    Judd, Jenni; Keleher, Helen

    2013-12-01

    Reorientation of the workforce in primary health care is a complex process and requires specific strategies and interventions. Primary health care providers are a key health care workforce that is expected to deliver tangible outcomes from disease prevention and health promotion strategies. This paper describes a training intervention that occurred as part of a broader participatory action research process for building health promotion capacity in the primary health care workforce. Participatory action research (PAR) was conducted over six action and reflection cycles in a two-year period (2001-02) in an urban community health setting in the Northern Territory. One of the PAR cycles was a training intervention that was identified as a need from a survey in the first action and reflection cycle. This training was facilitated by a health promotion specialist, face-to-face and comprised five 3.5-h sessions over a 5-month period. A pre-post questionnaire was used to measure the knowledge and skills components of the training intervention. The results reinforced the importance of using a participatory approach that involved the primary health care providers themselves. Multiple strategies such as workforce development within capacity building frameworks assisted in shifting work practice more upstream. Additionally, these strategies encouraged more reflective practice and built social capital within the primary health care workforce. Lessons from practice reinforce that workforce development influenced work practice change and is an important element in building the health promotion capacity of primary health care centres. SO WHAT?: Workforce development is critical for reorienting health services. Health promotion specialists play an important role in reorienting practice, which is only effective when combined with other strategies, and driven and led by the primary health care workforce.

  5. Application of spectroscopy and super-resolution microscopy: Excited state

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattacharjee, Ujjal

    Photophysics of inorganic materials and organic molecules in complex systems have been extensively studied with absorption and emission spectroscopy.1-4 Steady-state and time-resolved fluorescence studies are commonly carried out to characterize excited-state properties of fluorophores. Although steady-state fluorescence measurements are widely used for analytical applications, time-resolved fluorescence measurements provide more detailed information about excited-state properties and the environment in the vicinity of the fluorophore. Many photophysical processes, such as photoinduced electron transfer (PET), rotational reorientation, solvent relaxation, and energy transfer, occur on a nanosecond (10 -9 s) timescale, thus affecting the lifetime of the fluorophores. Moreover, time-resolved microscopy methods, such asmore » lifetimeimaging, combine the benefits of the microscopic measurement and information-rich, timeresolved data. Thus, time-resolved fluorescence spectroscopy combined with microscopy can be used to quantify these processes and to obtain a deeper understanding of the chemical surroundings of the fluorophore in a small area under investigation. This thesis discusses various photophysical and super-resolution microscopic studies of organic and inorganic materials, which have been outlined below.« less

  6. Experimental and Theoretical Study of Molecular Response of Amine Bases in Organic Solvents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kathmann, Shawn M.; Cho, Herman M.; Chang, Tsun-Mei

    2014-05-08

    Reorientational correlation times of various amine bases (viz., pyridine, 2,6-lutidene, 2,2,6,6-tetramethylpiperidine) and organic solvents (dichloromethane, toluene) were determined by solution-state NMR relaxation time measurements and compared with predictions from molecular dynamics (MD) simulations. The bases and solvents are reagents in complex reactions involving Frustrated Lewis Pairs (FLP), which display remarkable catalytic activity in metal-free H2 scission. The comparison of measured and simulated correlation times is a key test of the ability of recent MD and quantum electronic structure calculations to elucidate the mechanism of FLP activity. Correla- tion times were found to be in the range 1.4-3.4 ps (NMR) andmore » 1.23-5.28 ps (MD) for the amines, and 0.9-2.3 ps (NMR) and 0.2-1.7 ps (MD) for the solvent molecules. This work was supported by the U.S. Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences. Pacic Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle.« less

  7. Open University Environmental Education and Training.

    ERIC Educational Resources Information Center

    Blackmore, Christine

    1996-01-01

    Describes the approach to environmental education courses at Open University. Includes broad course content, team teaching approach, and philosophy of reorienting education towards sustainable development. Course material for open learning includes self-contained study packs as well as course texts, video, audio, and computer software. Nonformal…

  8. A proposed streamflow-data program for Wisconsin

    USGS Publications Warehouse

    Campbell, Roy E.; Dreher, Frederick C.

    1970-01-01

    The historical data acquired and the new data to be collected form the basis for analytical and interpretive reports. Recommendations were made as to expanding or initiating such studies. Streamflow data collection should be a continuing effort, reoriented as necessary to meet the changing needs.

  9. A Behavioral Study of Distraction by Vibrotactile Novelty

    ERIC Educational Resources Information Center

    Parmentier, Fabrice B. R.; Ljungberg, Jessica K.; Elsley, Jane V.; Lindkvist, Markus

    2011-01-01

    Past research has demonstrated that the occurrence of unexpected task-irrelevant changes in the auditory or visual sensory channels captured attention in an obligatory fashion, hindering behavioral performance in ongoing auditory or visual categorization tasks and generating orientation and re-orientation electrophysiological responses. We report…

  10. Alternative Strategies for Funding a General Dentistry Residency Program.

    ERIC Educational Resources Information Center

    Kralewski, John E.; Wiggins, Carla

    1987-01-01

    Three alternative program funding approaches used in other professions are examined: (1) the reorientation of selected dental schools toward graduate education, (2) emphasizing and marketing the service aspects of the programs, and (3) developing education programs as in-house training for large organizations. (MSE)

  11. Report: Design for Objective 8.4 Could Be Improved by Reorienting Focus on Outcomes

    EPA Pesticide Factsheets

    Report #2002-P-000002, November 21, 2001. Observations on whether the designs for Objective 8.4 and the research portions of Goal 8 were consistent with the intent of the GPRA Act, i.e., conducive to achieving outcomerelated results.

  12. Structural Basis of the Induced-Fit Mechanism of 1,4-Dihydroxy-2-Naphthoyl Coenzyme A Synthase from the Crotonase Fold Superfamily

    PubMed Central

    Li, Jie; Li, Yan; Jiang, Ming; Zhou, Jiahai; Guo, Zhihong

    2013-01-01

    1, 4-Dihydroxy-2-naphthoyl coenzyme A (DHNA-CoA) synthase is a typical crotonase fold enzyme with an implicated role of conformational changes in catalysis. We have identified these conformational changes by determining the structures of its Escherichia coli and Synechocystis sp. PCC6803 orthologues in complex with a product analog. The structural changes include the folding of an active-site loop into a β-hairpin and significant reorientation of a helix at the carboxy terminus. Interestingly, a new interface is formed between the ordered loop and the reoriented helix, both of which also form additional interactions with the coenzyme A moiety of the ligand. Site-directed mutation of the amino acid residues involved in these ligand-induced interactions significantly diminishes the enzyme activity. These results suggest a catalytically essential induced-fit that is likely initiated by the enzyme-ligand interactions at the active site. PMID:23658663

  13. Mechanical adaptability of the Bouligand-type structure in natural dermal armour

    NASA Astrophysics Data System (ADS)

    Zimmermann, Elizabeth A.; Gludovatz, Bernd; Schaible, Eric; Dave, Neil K. N.; Yang, Wen; Meyers, Marc A.; Ritchie, Robert O.

    2013-10-01

    Arapaima gigas, a fresh water fish found in the Amazon Basin, resist predation by piranhas through the strength and toughness of their scales, which act as natural dermal armour. Arapaima scales consist of a hard, mineralized outer shell surrounding a more ductile core. This core region is composed of aligned mineralized collagen fibrils arranged in distinct lamellae. Here we show how the Bouligand-type (twisted plywood) arrangement of collagen fibril lamellae has a key role in developing their unique protective properties, by using in situ synchrotron small-angle X-ray scattering during mechanical tensile tests to observe deformation mechanisms in the fibrils. Specifically, the Bouligand-type structure allows the lamellae to reorient in response to the loading environment; remarkably, most lamellae reorient towards the tensile axis and deform in tension through stretching/sliding mechanisms, whereas other lamellae sympathetically rotate away from the tensile axis and compress, thereby enhancing the scale’s ductility and toughness to prevent fracture.

  14. Syndecan defines precise spindle orientation by modulating Wnt signaling in C. elegans.

    PubMed

    Dejima, Katsufumi; Kang, Sukryool; Mitani, Shohei; Cosman, Pamela C; Chisholm, Andrew D

    2014-11-01

    Wnt signals orient mitotic spindles in development, but it remains unclear how Wnt signaling is spatially controlled to achieve precise spindle orientation. Here, we show that C. elegans syndecan (SDN-1) is required for precise orientation of a mitotic spindle in response to a Wnt cue. We find that SDN-1 is the predominant heparan sulfate (HS) proteoglycan in the early C. elegans embryo, and that loss of HS biosynthesis or of the SDN-1 core protein results in misorientation of the spindle of the ABar blastomere. The ABar and EMS spindles both reorient in response to Wnt signals, but only ABar spindle reorientation is dependent on a new cell contact and on HS and SDN-1. SDN-1 transiently accumulates on the ABar surface as it contacts C, and is required for local concentration of Dishevelled (MIG-5) in the ABar cortex adjacent to C. These findings establish a new role for syndecan in Wnt-dependent spindle orientation. © 2014. Published by The Company of Biologists Ltd.

  15. Reorientation-effect measurement of the <21+∥E2̂∥21+> matrix element in 10Be

    NASA Astrophysics Data System (ADS)

    Orce, J. N.; Drake, T. E.; Djongolov, M. K.; Navrátil, P.; Triambak, S.; Ball, G. C.; Al Falou, H.; Churchman, R.; Cross, D. S.; Finlay, P.; Forssén, C.; Garnsworthy, A. B.; Garrett, P. E.; Hackman, G.; Hayes, A. B.; Kshetri, R.; Lassen, J.; Leach, K. G.; Li, R.; Meissner, J.; Pearson, C. J.; Rand, E. T.; Sarazin, F.; Sjue, S. K. L.; Stoyer, M. A.; Sumithrarachchi, C. S.; Svensson, C. E.; Tardiff, E. R.; Teigelhoefer, A.; Williams, S. J.; Wong, J.; Wu, C. Y.

    2012-10-01

    The highly-efficient and segmented TIGRESS γ-ray spectrometer at TRIUMF has been used to perform a reorientation-effect Coulomb-excitation study of the 21+ state at 3.368 MeV in 10Be. This is the first Coulomb-excitation measurement that enables one to obtain information on diagonal matrix elements for such a high-lying first excited state from γ-ray data. With the availability of accurate lifetime data, a value of -0.110±0.087 eb is determined for the <21+∥E2̂∥21+> diagonal matrix element, which assuming the rotor model, leads to a negative spectroscopic quadrupole moment of QS(21+)=-0.083±0.066 eb. This result is in agreement with both no-core shell-model calculations performed in this work with the CD-Bonn 2000 two-nucleon potential and large shell-model spaces, and Green's function Monte Carlo predictions with two- plus three-nucleon potentials.

  16. Phase transformation and deformation behavior of NiTi-Nb eutectic joined NiTi wires

    PubMed Central

    Wang, Liqiang; Wang, Cong; Zhang, Lai-Chang; Chen, Liangyu; Lu, Weijie; Zhang, Di

    2016-01-01

    NiTi wires were brazed together via eutectic reaction between NiTi and Nb powder deposited at the wire contact region. Phase transformation and deformation behavior of the NiTi-Nb eutectic microstructure were investigated using transmission electron microscopy (TEM) and cyclic loading-unloading tests. Results show that R phase and B19′ martensite transformation are induced by plastic deformation. R phase transformation, which significantly contributes to superelasticity, preferentially occurs at the interfaces between NiTi and eutectic region. Round-shaped Nb-rich phase with rod-like and lamellar-type eutectics are observed in eutectic regions. These phases appear to affect the deformation behavior of the brazed NiTi-Nb region via five distinct stages in stress-strain curves: (I) R phase reorientation, (II) R phase transformation from parent phase, (III) elastic deformation of reoriented martensite accompanied by the plastic deformation of Nb-rich phase and lamellar NiTi-Nb eutectic, (IV) B19′ martensitic transformation, and (V) plastic deformation of the specimen. PMID:27049025

  17. Photoreceptor-mediated bending towards UV-B in Arabidopsis.

    PubMed

    Vandenbussche, Filip; Tilbrook, Kimberley; Fierro, Ana Carolina; Marchal, Kathleen; Poelman, Dirk; Van Der Straeten, Dominique; Ulm, Roman

    2014-06-01

    Plants reorient their growth towards light to optimize photosynthetic light capture--a process known as phototropism. Phototropins are the photoreceptors essential for phototropic growth towards blue and ultraviolet-A (UV-A) light. Here we detail a phototropic response towards UV-B in etiolated Arabidopsis seedlings. We report that early differential growth is mediated by phototropins but clear phototropic bending to UV-B is maintained in phot1 phot2 double mutants. We further show that this phototropin-independent phototropic response to UV-B requires the UV-B photoreceptor UVR8. Broad UV-B-mediated repression of auxin-responsive genes suggests that UVR8 regulates directional bending by affecting auxin signaling. Kinetic analysis shows that UVR8-dependent directional bending occurs later than the phototropin response. We conclude that plants may use the full short-wavelength spectrum of sunlight to efficiently reorient photosynthetic tissue with incoming light. © The Author 2014. Published by the Molecular Plant Shanghai Editorial Office in association with Oxford University Press on behalf of CSPB and IPPE, SIBS, CAS.

  18. Meeting patient expectations: healthcare professionals and service re-engineering.

    PubMed

    Laing, Angus

    2002-08-01

    A central theme underpinning the reform of healthcare systems in western economies since the 1980s has been the emphasis on reorienting service provision around the patient. Healthcare organizations have been forced to re-appraise the design of the service delivery process, specifically the service encounter, to take account of these changing patient expectations. This reorientation of healthcare services around the patient has fundamental implications for healthcare professionals, specifically challenging the dominance of service professionals in the design and delivery of health services. Utilizing a qualitative methodological framework, this paper explores the responses of healthcare professionals to service redesign initiatives implemented in acute NHS hospitals in Scotland and considers the implications of such professional responses for the development of patient-focused service delivery. Within this, it specifically examines evolving professional perspectives on the place of a service user focus in a publicly funded healthcare system, professional attitudes towards private sector managerial practices, and the dynamics of changing professional behaviour.

  19. Evolved to fail: Bacteria induce flagellar buckling to reorient

    NASA Astrophysics Data System (ADS)

    Son, Kwangmin; Guasto, Jeffrey S.; Stocker, Roman

    2012-11-01

    Many marine bacteria swim with a single helical flagellum connected to a rotary motor via a 100 nm long universal joint called the ``hook.'' While these bacteria have seemingly just one degree of freedom, allowing them to swim only back and forth, they in fact exhibit large angular reorientations mediated by off-axis ``flicks'' of their flagellum. High-speed video microscopy revealed the mechanism underpinning this turning behavior: the buckling of the hook during the exceedingly brief (10 ms) forward run that follows a reversal. Direct measurements of the hook's mechanical properties corroborated this result, as the hook's structural stability is governed by the Sperm number, which compares the compressive load from propulsion to the elastic restoring force of the hook. Upon decreasing the Sperm number below a critical value by reducing the swimming speed, the frequency of flicks diminishes sharply, consistent with the criticality of buckling. This elegant, under-actuated turning mechanism appears widespread among marine bacteria and may provide a novel design concept in micro-robotics.

  20. Electrical response of liquid crystal cells doped with multi-walled carbon nanotubes.

    PubMed

    García-García, Amanda; Vergaz, Ricardo; Algorri, José Francisco; Quintana, Xabier; Otón, José Manuel

    2015-01-01

    The inclusion of nanoparticles modifies a number of fundamental properties of many materials. Doping of nanoparticles in self-organized materials such as liquid crystals may be of interest for the reciprocal interaction between the matrix and the nanoparticles. Elongated nanoparticles and nanotubes can be aligned and reoriented by the liquid crystal, inducing noticeable changes in their optical and electrical properties. In this work, cells of liquid crystal doped with high aspect ratio multi-walled carbon nanotubes have been prepared, and their characteristic impedance has been studied at different frequencies and excitation voltages. The results demonstrate alterations in the anisotropic conductivity of the samples with the applied electric field, which can be followed by monitoring the impedance evolution with the excitation voltage. Results are consistent with a possible electric contact between the coated substrates of the LC cell caused by the reorientation of the nanotubes. The reversibility of the doped system upon removal of the electric field is quite low.

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