Sample records for b-52 mother ship

  1. NASA's B-52 mother ship carries the X-43A and its booster rocket on a captive carry flight Jan. 26, 2004

    NASA Image and Video Library

    2004-01-26

    NASA's historic B-52 mother ship carried the X-43A and its Pegasus booster rocket on a captive carry flight from Edwards Air Force Base Jan. 26, 2004. The X-43A and its booster remained mated to the B-52 throughout the two-hour flight, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  2. Hitching a ride on NASA's B-52 mother ship, the X-43A scramjet performed a captive carry evaluation flight from Edwards Air Force Base, California, January 26, 2004

    NASA Image and Video Library

    2004-01-26

    Hitching a ride on the same B-52 mother ship that once launched X-15 research aircraft in the 1960s, NASA's X-43A scramjet and it's Pegasus booster rocket performed a captive carry evaluation flight from Edwards Air Force Base, California, January 26, 2004. The X-43 and it's booster remained mated to the B-52 throughout this mission, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  3. The black X-43A rides on the front of a modified Pegasus booster rocket hung from the special pylon under the wing of NASA's B-52B mother ship. The photo was taken during a captive carry flight Jan. 26, 2004 to verify systems before an upcoming launch

    NASA Image and Video Library

    2004-01-26

    The black X-43A rides on the front of a modified Pegasus booster rocket hung from the special pylon under the wing of NASA's B-52B mother ship. The photo was taken during a captive carry flight Jan. 26, 2004 to verify systems before an upcoming launch.

  4. 48 CFR 52.247-46 - Shipping Point(s) Used in Evaluation of F.o.b. Origin Offers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Evaluation of F.o.b. Origin Offers. 52.247-46 Section 52.247-46 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-46 Shipping Point(s) Used in Evaluation of F.o.b. Origin Offers. As prescribed in 47.305-3(b)(4)(ii), insert the following provision in f.o.b. origin solicitations...

  5. Mother ship and physical agents collaboration

    NASA Astrophysics Data System (ADS)

    Young, Stuart H.; Budulas, Peter P.; Emmerman, Philip J.

    1999-07-01

    This paper discusses ongoing research at the U.S. Army Research Laboratory that investigates the feasibility of developing a collaboration architecture between small physical agents and a mother ship. This incudes the distribution of planning, perception, mobility, processing and communications requirements between the mother ship and the agents. Small physical agents of the future will be virtually everywhere on the battlefield of the 21st century. A mother ship that is coupled to a team of small collaborating physical agents (conducting tasks such as Reconnaissance, Surveillance, and Target Acquisition (RSTA); logistics; sentry; and communications relay) will be used to build a completely effective and mission capable intelligent system. The mother ship must have long-range mobility to deploy the small, highly maneuverable agents that will operate in urban environments and more localized areas, and act as a logistics base for the smaller agents. The mother ship also establishes a robust communications network between the agents and is the primary information disseminating and receiving point to the external world. Because of its global knowledge and processing power, the mother ship does the high-level control and planning for the collaborative physical agents. This high level control and interaction between the mother ship and its agents (including inter agent collaboration) will be software agent architecture based. The mother ship incorporates multi-resolution battlefield visualization and analysis technology, which aids in mission planning and sensor fusion.

  6. X-38 Ship #2 Mated to B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This photo shows one of the X-38 lifting-body research vehicles mated to NASA's B-52 mothership in flight prior to launch. The B-52 has been a workhorse for the Dryden Flight Research Center for more than 40 years, carrying numerous research vehicles aloft and conducting a variety of other research flight experiments. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  7. X-38 Ship #2 Mated to B-52 Mothership in Flight

    NASA Image and Video Library

    1999-07-09

    This photo shows one of the X-38 lifting-body research vehicles mated to NASA's B-52 mothership in flight prior to launch. The B-52 has been a workhorse for the Dryden Flight Research Center for more than 40 years, carrying numerous research vehicles aloft and conducting a variety of other research flight experiments.

  8. 48 CFR 52.247-60 - Guaranteed Shipping Characteristics.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Guaranteed Shipping Characteristics. 52.247-60 Section 52.247-60 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... information will be used to determine transportation costs for evaluation purposes. If the offeror does not...

  9. 48 CFR 52.247-60 - Guaranteed Shipping Characteristics.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Guaranteed Shipping Characteristics. 52.247-60 Section 52.247-60 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... information will be used to determine transportation costs for evaluation purposes. If the offeror does not...

  10. X-38 Ship #2 in Free Flight after Release from B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The X-38 research vehicle drops away from NASA's B-52 mothership immediately after being released from the B-52's wing pylon. More than 30 years earlier, this same B-52 launched the original lifting-body vehicles flight tested by NASA and the Air Force at what is now called the Dryden Flight Research Center and the Air Force Flight Test Center. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the

  11. Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus.

    PubMed

    Reed, Joanne H; Gorny, Miroslaw K; Li, Liuzhe; Cardozo, Timothy; Buyon, Jill P; Clancy, Robert M

    2017-05-01

    The detection of cardiac conduction defects in an 18-24 week old foetus in the absence of structural abnormalities predicts with near certainty the presence of autoantibodies against 60kD and 52kD SSA/Ro in the mother regardless of her health status. Previous studies have emphasized these autoantibodies as key mediators of tissue injury. The aim of this study was to focus on the anti-Ro52 response to determine whether these autoantibodies originate from progenitors that are inherently self-reactive or from B-cells that acquire self-reactivity during an immune response. We traced the evolution of two anti-Ro52 autoantibodies isolated from circulating IgG1-switched B-cells from an asymptomatic mother of a child with third degree congenital heart block. The autoantibodies were expressed as their immune form and as pre-immune ancestors by reverting somatic mutations to germline sequence. The reactivity of pre-immune and immune antibodies for Ro52, Ro60, La and DNA was measured. Both anti-Ro52 autoantibodies exhibited a low frequency of somatic mutations (3-4%) and utilised the same heavy and light chain genes but represented distinct clones based on differing complementarity determining region sequences. Pre- and post-immune antibodies showed specific binding to Ro52 with no measurable reactivity for other autoantigens. Ro52 binding was higher for immune antibodies compared to pre-immune counterparts demonstrating that autoreactivity was enhanced by affinity maturation. These data indicate that Ro52 reactivity is an intrinsic property of the germline antibody repertoire in a mother with a pathogenic antibody defined by cardiac injury in her offspring, and implies defects in both central and peripheral tolerance mechanisms. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Sizing of "Mother Ship and Catcher" Concepts for LEO Small Debris Capture

    NASA Technical Reports Server (NTRS)

    Bacon, John B.

    2009-01-01

    Most Low Earth Orbit (LEO) debris lies in a limited number of inclination "bands" associated with launch latitudes, or with specific useful orbit inclinations (such as polar orbits). Such narrow inclination bands generally have a uniform spread over all possible Right Ascensions of Ascending Node (RAANs), creating a different orbit plane for nearly every piece of debris. This complicates concept of rendezvous and capture for debris removal. However, a low-orbiting satellite will always phase in RAAN faster than debris objects in higher orbits at the same inclination, potentially solving the problem. Such a base can serve as a single space-based launch facility (a "mother ship") that can tend and then send tiny individual catcher devices for each debris object, as the facility drifts into the same RAAN as the higher object. This presentation will highlight characteristic system requirements of such an architecture, including structural and navigation requirements, power, mass and dV budgets for both the mother ship and the mass-produced common catcher devices that would clean out selected inclination bands. The altitude and inclination regime over which a band is to be cleared, the size distribution of the debris, and the inclusion of additional mission priorities all affect the sizing of the system. It is demonstrated that major LEO hazardous debris reductions can be realized in each band with a single LEO launch of a single mother ship, with simple attached catchers of total mass less than typical commercial LEO launch capability.

  13. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  14. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  15. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  16. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  17. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  18. Stress Analysis of B-52B and B-52H Air-Launching Systems Failure-Critical Structural Components

    NASA Technical Reports Server (NTRS)

    Ko, William L.

    2005-01-01

    The operational life analysis of any airborne failure-critical structural component requires the stress-load equation, which relates the applied load to the maximum tangential tensile stress at the critical stress point. The failure-critical structural components identified are the B-52B Pegasus pylon adapter shackles, B-52B Pegasus pylon hooks, B-52H airplane pylon hooks, B-52H airplane front fittings, B-52H airplane rear pylon fitting, and the B-52H airplane pylon lower sway brace. Finite-element stress analysis was performed on the said structural components, and the critical stress point was located and the stress-load equation was established for each failure-critical structural component. The ultimate load, yield load, and proof load needed for operational life analysis were established for each failure-critical structural component.

  19. B-52B Cockpit Instrument Panel

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This photo shows a close-up view of the instrument panel in the cockpit of NASA's B-52 research aircraft. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the HiMAT, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster

  20. 27 CFR 26.96b - Permit to ship.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Permit to ship. 26.96b... Liquors and Articles in Puerto Rico Wine § 26.96b Permit to ship. Wine released from bonded storage under § 26.95 or § 26.96 may not be shipped to the United States until permit for such shipment has been...

  1. 27 CFR 26.96b - Permit to ship.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Permit to ship. 26.96b... Liquors and Articles in Puerto Rico Wine § 26.96b Permit to ship. Wine released from bonded storage under § 26.95 or § 26.96 may not be shipped to the United States until permit for such shipment has been...

  2. 27 CFR 26.96b - Permit to ship.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Permit to ship. 26.96b... Liquors and Articles in Puerto Rico Wine § 26.96b Permit to ship. Wine released from bonded storage under § 26.95 or § 26.96 may not be shipped to the United States until permit for such shipment has been...

  3. 27 CFR 26.96b - Permit to ship.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Permit to ship. 26.96b... Liquors and Articles in Puerto Rico Wine § 26.96b Permit to ship. Wine released from bonded storage under § 26.95 or § 26.96 may not be shipped to the United States until permit for such shipment has been...

  4. 27 CFR 26.96b - Permit to ship.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Permit to ship. 26.96b... Liquors and Articles in Puerto Rico Wine § 26.96b Permit to ship. Wine released from bonded storage under § 26.95 or § 26.96 may not be shipped to the United States until permit for such shipment has been...

  5. Aberrant antibody affinity selection in SHIP-deficient B cells.

    PubMed

    Leung, Wai-Hang; Tarasenko, Tatiana; Biesova, Zuzana; Kole, Hemanta; Walsh, Elizabeth R; Bolland, Silvia

    2013-02-01

    The strength of the Ag receptor signal influences development and negative selection of B cells, and it might also affect B-cell survival and selection in the GC. Here, we have used mice with B-cell-specific deletion of the 5'-inositol phosphatase SHIP as a model to study affinity selection in cells that are hyperresponsive to Ag and cytokine receptor stimulation. In the absence of SHIP, B cells have lower thresholds for Ag- and interferon (IFN)-induced activation, resulting in augmented negative selection in the BM and enhanced B-cell maturation in the periphery. Despite a tendency to spontaneously downregulate surface IgM expression, SHIP deficiency does not alter anergy induction in response to soluble hen-egg lysozyme Ag in the MDA4 transgenic model. SHIP-deficient B cells spontaneously produce isotype-switched antibodies; however, they are poor responders in immunization and infection models. While SHIP-deficient B cells form GCs and undergo mutation, they are not properly selected for high-affinity antibodies. These results illustrate the importance of negative regulation of B-cell responses, as lower thresholds for B-cell activation promote survival of low affinity and deleterious receptors to the detriment of optimal Ab affinity maturation. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. EC02-0080-63

    NASA Image and Video Library

    2002-04-12

    NASA's new white B-52H, destined to join a veteran B-52B mother ship at NASA's Dryden Flight Research Center, was exhibited at the Boeing plant in Wichita, Kansas, April 12, 2002 during the 50th anniversary commemoration of the B-52 series of aircraft.

  7. 42 CFR 52b.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Definitions. 52b.2 Section 52b.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.2 Definitions. As used in this part: Act means the Public Health Service Act, as...

  8. 42 CFR 52b.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Definitions. 52b.2 Section 52b.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.2 Definitions. As used in this part: Act means the Public Health Service Act, as...

  9. B-52 Launch Aircraft in Flight

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA's venerable B-52 mothership is seen here photographed from a KC-135 Tanker aircraft. The X-43 adapter is visible attached to the right wing. The B-52, used for launching experimental aircraft and for other flight research projects, has been a familiar sight in the skies over Edwards for more than 40 years and is also both the oldest B-52 still flying and the aircraft with the lowest flight time of any B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported

  10. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  11. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  12. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  13. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  14. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  15. B-52G crew noise exposure study

    NASA Astrophysics Data System (ADS)

    Decker, W. H.; Nixon, C. W.

    1985-08-01

    The B-52G aircraft produces acoustic environments that are potentially hazardous, interfere with voice communications and may degrade task performance. Numerous reports from aircrew of high noise levels at crew location have been documented for those B-52G aircraft that have been modified with the Offensive Avionics System. To alleviate and minimize the excessive noise exposures of aircrews, a study of the noise problem in the b-52G was deemed necessary. First, in-flight noise measurements were obtained at key personnel locations on a B-52G during a typical training mission. Then, extensive laboratory analyses were conducted on these in-flight noise data. The resulting noise exposure data were evaluated in terms of the various segments of and the total flight profile relative to allowable noise exposures. Finally, recommendations were developed for short term and long term approaches toward potential improvement in the B-52G noise exposure problem.

  16. B-52 Testing F-111 Parachute

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A mock-up of an F-111 cockpit section drops out of the bomb bay of NASA's B-52 mothership on a test flight of a new parachute system for the F-111 'Aardvark' bomber. The F-111's ejection system separated the entire cockpit from the rest of the aircraft, and a large parachute was then deployed to lower the cockpit section to the ground. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  17. B-52 Testing F-111 Parachute

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The main parachute begins to deploy on the mock-up of an F-111 'Aardvark' bomber cockpit section after being dropped from NASA's B-52 mothership during 1988 flight tests on improved parachute systems for the Air Force bomber. The F-111's ejection system separated the entire cockpit from the rest of the aircraft, and a large parachute was then deployed to lower the cockpit section to the ground. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of

  18. B-52 Flight Mission Symbology - Close up

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A close-up view of some of the mission markings that tell the story of the NASA B-52 mothership's colorful history. These particular markings denote some of the experiments the bomber conducted to develop parachute recovery systems for the solid rocket boosters used by the Space Shuttle. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported

  19. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  20. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  1. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  2. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  3. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  4. The second X-43A hypersonic research vehicle, mounted under the right wing of the B-52B launch aircraft, viewed from the B-52 cockpit

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research vehicle, mounted under the right wing of the B-52B launch aircraft, viewed from the B-52 cockpit. The crew is working on closing out the research vehicle, preparing it for flight.

  5. Pegasus Mated to B-52 Mothership - Front View

    NASA Technical Reports Server (NTRS)

    1991-01-01

    NASA's B-52 launch aircraft takes off with the second Pegasus vehicle under its wing from the Dryden Flight Research Facility (now the Dryden Flight Research Center), Edwards, California. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In addition, the B-52 served as the air

  6. Dryden B-52 Launch Aircraft on Dryden Ramp

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable B-52 mothership sits on the ramp in front of the Dryden Flight Research Center, Edwards, California. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the X-38, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  7. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A close-up of an experimental drag chute deploying in a cloud of dust behind NASA's B-52 research aircraft just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover

  8. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    An aerial view of NASA's B-52 research aircraft deploying an experimental drag chute just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid

  9. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    NASA's B-52 research aircraft deploys an experimental drag chute just after landing the runway at the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also

  10. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    An experimental drag chute deploys amidst a cloud of dust behind NASA's B-52 research aircraft just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  11. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A rear view of NASA's B-52 research aircraft deploying an experimental drag chute just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid

  12. B-52 stability augmentation system reliability

    NASA Technical Reports Server (NTRS)

    Bowling, T. C.; Key, L. W.

    1976-01-01

    The B-52 SAS (Stability Augmentation System) was developed and retrofitted to nearly 300 aircraft. It actively controls B-52 structural bending, provides improved yaw and pitch damping through sensors and electronic control channels, and puts complete reliance on hydraulic control power for rudder and elevators. The system has experienced over 300,000 flight hours and has exhibited service reliability comparable to the results of the reliability test program. Development experience points out numerous lessons with potential application in the mechanization and development of advanced technology control systems of high reliability.

  13. 46 CFR 111.52-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false General. 111.52-1 Section 111.52-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-1 General. The available short-circuit current must be computed...

  14. 46 CFR 111.52-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false General. 111.52-1 Section 111.52-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-1 General. The available short-circuit current must be computed...

  15. 46 CFR 111.52-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false General. 111.52-1 Section 111.52-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-1 General. The available short-circuit current must be computed...

  16. 46 CFR 111.52-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false General. 111.52-1 Section 111.52-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-1 General. The available short-circuit current must be computed...

  17. 46 CFR 111.52-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false General. 111.52-1 Section 111.52-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-1 General. The available short-circuit current must be computed...

  18. Wind-Tunnel Results of the B-52B with the X-43A Stack

    NASA Technical Reports Server (NTRS)

    Davis, Mark C.; Sim, Alexander G.; Rhode, Matthew; Johnson, Kevin D., Sr.

    2007-01-01

    A low-speed wind-tunnel test was performed with a 3%-scale model of a booster rocket mated to an X-43A research vehicle, a combination referred to as the Hyper-X launch vehicle. The test was conducted both in freestream air and in the presence of a partial model of the B-52B airplane. The objectives of the test were to obtain force and moment data to generate structural loads affecting the pylon of the B-52B airplane and to determine the aerodynamic influence of the B-52B on the Hyper-X launch vehicle for evaluating launch separation characteristics. The windtunnel test was conducted at a low-speed wind tunnel in Hampton, Virginia. All moments and forces reported are based either on the aerodynamic influence of the B-52B airplane or are for the Hyper-X launch vehicle in freestream air. Overall, the test showed that the B-52B airplane imparts a strong downwash onto the Hyper-X launch vehicle, reducing the net lift of the Hyper-X launch vehicle. Pitching and rolling moments are also imparted onto the booster and are a strong function of the launch-drop angle of attack.

  19. Dryden B-52 Launch Aircraft in Flight over Dryden

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable B-52 mothership flies over the main building at the Dryden Flight Research Center, Edwards, California. The B-52, used for launching experimental aircraft and for other flight research projects, has been a familiar sight in the skies over Edwards for more than 40 years and has also been both the oldest B-52 still flying and the aircraft with the lowest flight time of any B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of

  20. Pegasus Mated to B-52 Mothership - First Flight

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Pegasus air-launched space booster is carried aloft under the right wing of NASA's B-52 carrier aircraft on its first captive flight from the Dryden Flight Research Center, Edwards, California. The first of two scheduled captive flights was completed on November 9, 1989. Pegasus is used to launch satellites into low-earth orbits cheaply. In 1997, a Pegasus rocket booster was also modified to test a hypersonic experiment (PHYSX). An experimental 'glove,' installed on a section of its wing, housed hundreds of temperature and pressure sensors that sent hypersonic flight data to ground tracking facilities during the experiment's flight. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering

  1. X-15 Mated to B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1959-01-01

    One of three X-15 rocket-powered research aircraft being carried aloft under the wing of its B-52 mothership. The X-15 was air launched from the B-52 so the rocket plane would have enough fuel to reach its high speed and altitude test points. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. The X-15s made a total of 199 flights over a period of nearly 10 years and set world's unofficial speed and altitude records of 4,520 miles per hour (Mach 6.7) and 354,200 feet. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo manned spaceflight programs and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development

  2. 46 CFR 52.25-1 - General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false General. 52.25-1 Section 52.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-1 General. Requirements for fired boilers of various sizes and uses are referenced in Table 54.01-5(a) of...

  3. 46 CFR 52.25-1 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false General. 52.25-1 Section 52.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-1 General. Requirements for fired boilers of various sizes and uses are referenced in table 54.01-5(a) of...

  4. 46 CFR 52.25-1 - General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false General. 52.25-1 Section 52.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-1 General. Requirements for fired boilers of various sizes and uses are referenced in Table 54.01-5(a) of...

  5. 46 CFR 52.25-1 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false General. 52.25-1 Section 52.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-1 General. Requirements for fired boilers of various sizes and uses are referenced in table 54.01-5(a) of...

  6. 46 CFR 52.01-5 - Plans.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Plans. 52.01-5 Section 52.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-5 Plans. (a) Manufacturers intending to fabricate boilers to be installed on vessels shall submit detailed plans as required by subpart 50.20 of...

  7. 46 CFR 52.01-5 - Plans.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Plans. 52.01-5 Section 52.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-5 Plans. (a) Manufacturers intending to fabricate boilers to be installed on vessels shall submit detailed plans as required by subpart 50.20 of...

  8. 46 CFR 52.01-5 - Plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Plans. 52.01-5 Section 52.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-5 Plans. (a) Manufacturers intending to fabricate boilers to be installed on vessels shall submit detailed plans as required by subpart 50.20 of...

  9. 46 CFR 52.01-5 - Plans.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Plans. 52.01-5 Section 52.01-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-5 Plans. (a) Manufacturers intending to fabricate boilers to be installed on vessels shall submit detailed plans as required by subpart 50.20 of...

  10. 46 CFR 52.25-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false General. 52.25-1 Section 52.25-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-1 General. Requirements for fired boilers of various sizes and uses are referenced in Table 54.01-5(a) of...

  11. Wind Tunnel Results of the B-52B with the X-43A Stack

    NASA Technical Reports Server (NTRS)

    Davis, Mark C.; Sim, Alexander G.; Rhode, Matthew; Johnson, Kevin D.

    2006-01-01

    A low-speed wind-tunnel test was performed with a three-percent-scale model of a booster rocket mated to an X-43A research vehicle, a combination referred to as the Hyper-X launch vehicle. The test was conducted both in free-stream air and in the presence of a partial model of the B-52B airplane. The objectives of the test were to obtain force and moment data to generate structural loads affecting the pylon of the B-52B airplane and to determine the aerodynamic influence of the B-52B airplane on the Hyper-X launch vehicle to evaluate launch separation characteristics. The wind-tunnel test was conducted at a low-speed wind tunnel in Hampton, Virginia. All moments and forces reported are based either on the aerodynamic influence of the B-52B airplane or are for the Hyper-X launch vehicle in free-stream air. Overall, the test showed that the B-52B airplane imparts a strong downwash onto the Hyper-X launch vehicle, reducing the net lift of the Hyper-X launch vehicle. Also, pitching and rolling moments are imparted onto the booster and are a strong function of the launch-drop angle of attack.

  12. 46 CFR 503.52 - Senior agency official.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Senior agency official. 503.52 Section 503.52 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS PUBLIC INFORMATION Information Security Program § 503.52 Senior agency official. The Chairman of the Commission shall designate a senior agency...

  13. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  14. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  15. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  16. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  17. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  18. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  19. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  20. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  1. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  2. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  3. X-15 Mated to B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1960-01-01

    High-altitude contrails frame the B-52 mothership as it carries the X-15 aloft for a research flight on 13 April 1960 on Air Force Maj. Robert M. White's first X-15 flight. The X-15s were air-launched so that they would have enough rocket fuel to reach their high speed and altitude test points. For this early research flight, the X-15 was equipped with a pair of XLR-11 rocket engines until the XLR-99 was available. The X-15s made a total of 199 flights over a period of nearly 10 years--1959 to 1968--and set unofficial world speed and altitude records of 4,520 mph (Mach 6.7) and 354,200 feet. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo piloted spaceflight programs, and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several

  4. B-52 Flight Mission Symbology on Side of Craft

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A view of some of the mission markings, painted on the side of NASA's B-52 mothership, that tell the story of its colorful history. Just as combat aircraft would paint a bomb on the side of an aircraft for each bombing mission completed, NASA crew members painted a silhouette on the side of the B-52's fuselage to commemorate each drop of an X-15, lifting body, remotely piloted research vehicle, X-38 crew return vehicle, or other experimental vehicle or parachute system. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for

  5. Dryden B-52 Launch Aircraft on Edwards AFB Runway

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable workhorse, the B-52 mothership, rolls out on the Edwards AFB runway after a test flight in 1996. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the X-38, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  6. X-38 Mounted on Pylon of B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A close-up view of the X-38 research vehicle mounted under the wing of the B-52 mothership prior to a 1997 test flight. The X-38, which was designed to help develop technology for an emergency crew return vehicle (CRV) for the International Space Station, is one of many research vehicles the B-52 has carried aloft over the past 40 years. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  7. Spin Research Vehicle (SRV) in B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1981-01-01

    This in-flight photo of NASA's B-52 mothership shows the bomber carrying a subscale model of an Air Force F-15, a remotely piloted vehicle that was used to conduct spin research. The F-15 Remotely Piloted Research Vehicles (RPRV) was air launched from the B-52 at approximately 45,000 feet and was controlled by a pilot in a ground cockpit complete with flight controls and a television screen. The F-15 model in this particular configuration was known as the Spin Research Vehicle (SRV). NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST

  8. Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey.

    PubMed

    Sahin, Ziver; Bıcakcıgil, Muge; Aksu, Kenan; Kamali, Sevil; Akar, Servet; Onen, Fatos; Karadag, Omer; Ozbalkan, Zeynep; Ates, Askin; Ozer, Huseyin Te; Yilmaz, Vuslat; Seyahi, Emire; Ozturk, Mehmet A; Cefle, Ayse; Cobankara, Veli; Onat, A Mesut; Tunc, Ercan; Düzgün, Nursen; Aydin, Sibel Z; Yilmaz, Neslihan; Fresko, İzzet; Karaaslan, Yasar; Kiraz, Sedat; Akkoc, Nurullah; Inanc, Murat; Keser, Gokhan; Uyar, F Aytul; Direskeneli, Haner; Saruhan-Direskeneli, Güher

    2012-02-06

    HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they are associated with two different vasculitides (HLA-B*51 in Behçet's disease and HLA-B*52 in Takayasu's arteritis (TAK)) and with major clinical and immunological differences. In this study, we aimed to screen a large cohort of TAK patients from Turkey for the presence of HLA-B*51 and HLA-B*52 as susceptibility and severity factors. TAK patients (n = 330) followed at a total of 15 centers were included in the study. The mean age of the patients was 37.8 years, and 86% were women. DNA samples from the patients and healthy controls (HC; n = 210) were isolated, and the presence of HLA-B*51 or HLA-B*52 was screened for by using PCR with sequence-specific primers. We found a significant association of HLA-B*52 with TAK (20.9% vs HC = 6.7%, P = 0.000, OR = 3.7, 95% CI = 2.02 to 6.77). The distribution of HLA-B*51 did not differ between TAK patients and HCs (22.7% vs 24.8%, OR = 0.9, 95% CI = 0.60 to 1.34). The presence of HLA-B*52 decreased in late-onset patients (> 40 years of age; 12.0%, P = 0.024, OR = 0.43, 95% CI = 0.20 to 0.91). Patients with angiographic type I disease with limited aortic involvement also had a lower presence of HLA-B*52 compared to those with all other disease subtypes (13.1% vs 26%, P = 0.005, OR = 0.43, 95% CI = 0.23 to 0.78). In this study, the previously reported association of TAK with HLA-B*52 in other populations was confirmed in patients from Turkey. The functional relevance of HLA-B*52 in TAK pathogenesis needs to be explored further.

  9. 46 CFR 52.01-130 - Installation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Installation. 52.01-130 Section 52.01-130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements... the gas passages from the operating boilers. (2) Each main power boiler and auxiliary boiler shall be...

  10. 46 CFR 52.01-130 - Installation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Installation. 52.01-130 Section 52.01-130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements... the gas passages from the operating boilers. (2) Each main power boiler and auxiliary boiler shall be...

  11. 46 CFR 52.01-130 - Installation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Installation. 52.01-130 Section 52.01-130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements... the gas passages from the operating boilers. (2) Each main power boiler and auxiliary boiler shall be...

  12. 46 CFR 52.01-130 - Installation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Installation. 52.01-130 Section 52.01-130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements... the gas passages from the operating boilers. (2) Each main power boiler and auxiliary boiler shall be...

  13. SHIP-1 Deficiency in AID+ B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity.

    PubMed

    Chen, Yingjia; Hu, Fanlei; Dong, Xuejiao; Zhao, Meng; Wang, Jing; Sun, Xiaolin; Kim, Tae Jin; Li, Zhanguo; Liu, Wanli

    2017-11-01

    Unlike conventional B cells, regulatory B cells exhibit immunosuppressive functions to downregulate inflammation via IL-10 production. However, the molecular mechanism regulating the production of IL-10 is not fully understood. In this study, we report the finding that activation-induced cytidine deaminase (AID) is highly upregulated in the IL-10-competent B cell (B10) cell from Innp5d fl/fl Aicda Cre/+ mice, whereas the 5' inositol phosphatase SHIP-1 is downregulated. Notably, SHIP-1 deficiency in AID + B cells leads to a reduction in cell count and impaired IL-10 production by B10 cells. Furthermore, the Innp5d fl/fl Aicda Cre/+ mouse model shows B cell-dependent autoimmune lupus-like phenotypes, such as elevated IgG serum Abs, formation of spontaneous germinal centers, production of anti-dsDNA and anti-nuclear Abs, and the obvious deposition of IgG immune complexes in the kidney with age. We observe that these lupus-like phenotypes can be reversed by the adoptive transfer of B10 cells from control Innp5d fl/fl mice, but not from the Innp5d fl/fl Aicda Cre/+ mice. This finding highlights the importance of defective B10 cells in Innp5d fl/fl Aicda Cre/+ mice. Whereas p-Akt is significantly upregulated, MAPK and AP-1 activation is impaired in B10 cells from Innp5d fl/fl Aicda Cre/+ mice, resulting in the reduced production of IL-10. These results show that SHIP-1 is required for the maintenance of B10 cells and production of IL-10, and collectively suggests that SHIP-1 could be a new potential therapeutic target for the treatment of autoimmune diseases. Copyright © 2017 by The American Association of Immunologists, Inc.

  14. Hepatitis B immunoglobulin during pregnancy for prevention of mother-to-child transmission of hepatitis B virus.

    PubMed

    Eke, Ahizechukwu C; Eleje, George U; Eke, Uzoamaka A; Xia, Yun; Liu, Jiao

    2017-02-11

    ) and continuous outcome data using mean difference (MD) with 95% confidence intervals (CI). For meta-analyses, we used a fixed-effect model and a random-effects model, along with an assessment of heterogeneity. If there were statistically significant discrepancies in the results, we reported the more conservative point estimate. If the two estimates were equal, we used the estimate with the widest CI as our main result. We assessed bias control using the Cochrane Hepato-Biliary Group suggested bias risk domains and risk of random errors using Trial Sequential Analysis (TSA). We assessed the quality of the evidence using GRADE. All 36 included trials originated from China and were at overall high risk of bias. The trials included 6044 pregnant women who were HBsAg, HBeAg, or hepatitis B virus DNA (HBV-DNA) positive. Only seven trials reported inclusion of HBeAg-positive mothers. All 36 trials compared HBIG versus no intervention. None of the trials used placebo.Most of the trials assessed HBIG 100 IU (two trials) and HBIG 200 IU (31 trials). The timing of administration of HBIG varied; 30 trials administered three doses of HBIG 200 IU at 28, 32, and 36 weeks of pregnancy. None of the trials reported all-cause mortality or other serious adverse events in the mothers or babies. Serological signs of hepatitis B infection of the newborns were reported as HBsAg, HBeAg, and HBV-DNA positive results at end of follow-up. Twenty-nine trials reported HBsAg status in newborns (median 1.2 months of follow-up after birth; range 0 to 12 months); seven trials reported HBeAg status (median 1.1 months of follow-up after birth; range 0 to 12 months); and 16 trials reported HBV-DNA status (median 1.2 months of follow-up; range 0 to 12 months). HBIG reduced mother-to-child transmission (MTCT) of HBsAg when compared with no intervention (179/2769 (6%) with HBIG versus 537/2541 (21%) with no intervention; RR 0.30, TSA-adjusted CI 0.20 to 0.52; I 2 = 36%; 29 trials; 5310 participants; very

  15. Pegasus Engine Ignites after Drop from B-52 Mothership

    NASA Image and Video Library

    1991-07-17

    Against the midnight blue of a high-altitude sky, Orbital Sciences’ Pegasus winged rocket booster ignites after being dropped from NASA’s B-52 mothership on a July 1991 flight. A NASA chase plane for the flight is also visible above the rocket and below the B-52.

  16. B-52B/DTV (Drop Test Vehicle) flight test results: Drop test missions

    NASA Technical Reports Server (NTRS)

    Doty, L. J.

    1985-01-01

    The NASA test airplane, B-52B-008, was a carrier for drop tests of the shuttle booster recovery parachute system. The purpose of the test support by Boeing was to monitor the vertical loads on the pylon hooks. The hooks hold the Drop Test Vehicle to the B-52 pylon during drop test missions. The loads were monitored to assure the successful completion of the flight and the safety of the crew.

  17. 46 CFR 52.25-20 - Exhaust gas boilers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Exhaust gas boilers. 52.25-20 Section 52.25-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-20 Exhaust gas boilers. Exhaust gas boilers with a maximum allowable working pressure...

  18. 46 CFR 52.25-20 - Exhaust gas boilers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Exhaust gas boilers. 52.25-20 Section 52.25-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-20 Exhaust gas boilers. Exhaust gas boilers with a maximum allowable working pressure...

  19. 46 CFR 52.25-20 - Exhaust gas boilers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Exhaust gas boilers. 52.25-20 Section 52.25-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-20 Exhaust gas boilers. Exhaust gas boilers with a maximum allowable working pressure...

  20. 46 CFR 52.25-20 - Exhaust gas boilers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Exhaust gas boilers. 52.25-20 Section 52.25-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-20 Exhaust gas boilers. Exhaust gas boilers with a maximum allowable working pressure...

  1. 46 CFR 52.25-20 - Exhaust gas boilers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Exhaust gas boilers. 52.25-20 Section 52.25-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-20 Exhaust gas boilers. Exhaust gas boilers with a maximum allowable working pressure...

  2. 46 CFR 503.52 - Senior agency official.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Senior agency official. 503.52 Section 503.52 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS PUBLIC INFORMATION Information Security...'s information security program, which includes oversight (self-inspection) and security information...

  3. 46 CFR 52.01-5 - Plans.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Plans. 52.01-5 Section 52.01-5 Shipping COAST GUARD... Plans. (a) Manufacturers intending to fabricate boilers to be installed on vessels shall submit detailed plans as required by subpart 50.20 of this subchapter. The plans, including design calculations, must be...

  4. HL-10 on lakebed with B-52 flyby

    NASA Technical Reports Server (NTRS)

    1969-01-01

    NASA research pilot Bill Dana takes a moment to watch NASA's NB-52B cruise overhead after a research flight in the HL-10. On the left, John Reeves can be seen at the cockpit of the lifting body. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2-F2/F3, provided an excellent starting point for designers of future entry vehicles, including the

  5. 46 CFR 52.01-40 - Materials and workmanship.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Materials and workmanship. 52.01-40 Section 52.01-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-40 Materials and workmanship. All materials to be used in any of the work specified in the...

  6. 46 CFR 52.01-40 - Materials and workmanship.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Materials and workmanship. 52.01-40 Section 52.01-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-40 Materials and workmanship. All materials to be used in any of the work specified in the...

  7. 46 CFR 52.01-40 - Materials and workmanship.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Materials and workmanship. 52.01-40 Section 52.01-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-40 Materials and workmanship. All materials to be used in any of the work specified in the...

  8. 46 CFR 52.01-40 - Materials and workmanship.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Materials and workmanship. 52.01-40 Section 52.01-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-40 Materials and workmanship. All materials to be used in any of the work specified in the...

  9. 46 CFR 52.01-40 - Materials and workmanship.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Materials and workmanship. 52.01-40 Section 52.01-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-40 Materials and workmanship. All materials to be used in any of the work specified in the...

  10. Sizing of "Mother Ship and Catcher" Missions for LEO Small Debris and for GEO Large Object Capture

    NASA Technical Reports Server (NTRS)

    Bacon, John B.

    2009-01-01

    Most LEO debris lies in a limited number of inclination "bands" associated with specific useful orbits. Objects in such narrow inclination bands have all possible Right Ascensions of Ascending Node (RAANs), creating a different orbit plane for nearly every piece of debris. However, a low-orbiting satellite will always phase in RAAN faster than debris objects in higher orbits at the same inclination, potentially solving the problem. Such a low-orbiting base can serve as a "mother ship" that can tend and then send small, disposable common individual catcher/deboost devices--one for each debris object--as the facility drifts into the same RAAN as each higher object. The dV necessary to catch highly-eccentric orbit debris in the center of the band alternatively allows the capture of less-eccentric debris in a wider inclination range around the center. It is demonstrated that most LEO hazardous debris can be removed from orbit in three years, using a single LEO launch of one mother ship--with its onboard magazine of freeflying low-tech catchers--into each of ten identified bands, with second or potentially third launches into only the three highest-inclination bands. The nearly 1000 objects near the geostationary orbit present special challenges in mass, maneuverability, and ultimate disposal options, leading to a dramatically different architecture and technology suite than the LEO solution. It is shown that the entire population of near-GEO derelict objects can be gathered and tethered together within a 3 year period for future scrap-yard operations using achievable technologies and only two earth launches.

  11. 46 CFR 111.52-3 - Systems below 1500 kilowatts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Systems below 1500 kilowatts. 111.52-3 Section 111.52-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-3 Systems below 1500 kilowatts. The...

  12. 46 CFR 111.52-3 - Systems below 1500 kilowatts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Systems below 1500 kilowatts. 111.52-3 Section 111.52-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-3 Systems below 1500 kilowatts. The...

  13. 46 CFR 52.25-15 - Fired thermal fluid heaters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Fired thermal fluid heaters. 52.25-15 Section 52.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-15 Fired thermal fluid heaters. (a) Fired thermal fluid heaters shall be designed...

  14. 46 CFR 52.25-15 - Fired thermal fluid heaters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Fired thermal fluid heaters. 52.25-15 Section 52.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-15 Fired thermal fluid heaters. (a) Fired thermal fluid heaters shall be designed...

  15. 46 CFR 52.25-15 - Fired thermal fluid heaters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Fired thermal fluid heaters. 52.25-15 Section 52.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-15 Fired thermal fluid heaters. (a) Fired thermal fluid heaters shall be designed...

  16. X-38 Mounted on Pylon of B-52 Mothership

    NASA Image and Video Library

    1997-07-06

    A close-up view of the X-38 research vehicle mounted under the wing of the B-52 mothership prior to a 1997 test flight. The X-38, which was designed to help develop technology for an emergency crew return vehicle (CRV) for the International Space Station, is one of many research vehicles the B-52 has carried aloft over the past 40 years.

  17. X-38 on B-52 Wing Pylon - View from Observation Window

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A unique, close-up view of the X-38 under the wing of NASA's B-52 mothership prior to launch of the lifting-body research vehicle. The photo was taken from the observation window of the B-52 bomber as it banked in flight. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In

  18. 46 CFR 153.903 - Operating a United States ship in special areas: Categories A, B, and C.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Operating a United States ship in special areas: Categories A, B, and C. 153.903 Section 153.903 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Documents and Cargo...

  19. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  20. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  1. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  2. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  3. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  4. Status of display systems in B-52H

    NASA Astrophysics Data System (ADS)

    Hopper, Darrel G.; Meyer, Frederick M.; Wodke, Kenneth E.

    1999-08-01

    Display technologies for the B-52 were selected some 40 years ago have become unsupportable. Electromechanical and old cathode ray tube technologies, including an exotic six-gun 13 in. tube, have become unsupportable due to the vanishing vendor syndrome. Thus, it is necessary to insert new technologies which will be available for the next 40 years to maintain the capability heretofore provided by those now out of favor with the commercial sector. With this paper we begin a look at the status of displays in the B-52H, which will remain in inventory until 2046 according to current plans. From a component electronics technology perspective, such as displays, the B-52H provides several 10-year life cycle cost (LCC) planning cycles to consider multiple upgrades. Three Productivity, Reliability, Availability, and Maintainability (PRAM) projects are reviewed to replace 1950s CRTs in several sizes: 3, 9, and 13 in. A different display technology has been selected in each case. Additional display upgrades in may be anticipated and are discussed.

  5. 46 CFR 52.20-25 - Setting (modifies PFT-46).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Setting (modifies PFT-46). 52.20-25 Section 52.20-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-25 Setting (modifies PFT-46). (a) The method of supporting firetube boilers shall be as indicated in PFT-46 of...

  6. 46 CFR 52.20-25 - Setting (modifies PFT-46).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Setting (modifies PFT-46). 52.20-25 Section 52.20-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-25 Setting (modifies PFT-46). (a) The method of supporting firetube boilers shall be as indicated in PFT-46 of...

  7. 46 CFR 52.20-25 - Setting (modifies PFT-46).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Setting (modifies PFT-46). 52.20-25 Section 52.20-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-25 Setting (modifies PFT-46). (a) The method of supporting firetube boilers shall be as indicated in PFT-46 of...

  8. 46 CFR 52.20-25 - Setting (modifies PFT-46).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Setting (modifies PFT-46). 52.20-25 Section 52.20-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-25 Setting (modifies PFT-46). (a) The method of supporting firetube boilers shall be as indicated in PFT-46 of...

  9. 46 CFR 52.20-25 - Setting (modifies PFT-46).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Setting (modifies PFT-46). 52.20-25 Section 52.20-25 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-25 Setting (modifies PFT-46). (a) The method of supporting firetube boilers shall be as indicated in PFT-46 of...

  10. The effects of aircraft (B-52) overflights on ancient structures

    NASA Astrophysics Data System (ADS)

    Battis, J. C.

    1994-03-01

    To simulate combat missions for the American bomber force, the Air Combat Command conducts low altitude training flights along routes throughout the U.S.A. This paper presents the results of an effort to evaluate the effect of these overflights on the many archaeologically significant structures located beneath the training routes. This study has shown that: (1) low overflights can induce measurable vibrations in these ancient structures; (2) the overflight induced motions do not constitute an appreciable threat to the sites; and (3) the observed levels of motion are no greater than those induced by sources in the natural environment. Although these findings are specific to overflights by B-52s, comparison of the low frequency acoustic signature of the B-52 and that of the B-1B overflights should not pose a significantly greater threat to the structures than B-52 overflights.

  11. 77 FR 33307 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Operation Regulation; Lake Washington Ship Canal, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of... operating schedule that governs the Montlake Bridge across the Lake Washington Ship Canal, mile 5.2, at... crosses the Lake Washington Ship Canal at mile 5.2 and while in the closed position provides 30 feet of...

  12. Assessing the knowledge of expectant mothers on mother-to-child transmission of viral hepatitis B in Upper West region of Ghana.

    PubMed

    Dun-Dery, Frederick; Adokiya, Martin Nyaaba; Walana, Williams; Yirkyio, Ernestina; Ziem, Juventus B

    2017-06-12

    Viral Hepatitis B is of a major public health concern globally, especially in developing countries. Expectant mothers' knowledge of Mother-To-Child Transmission (MTCT) of the disease is significant in preventing the spread from an infected mother to her child. This study sought to assess the expectant mothers' knowledge of Mother-To-Child Transmission of viral hepatitis B in the Wa Municipality and Lawra District of Upper West Region, Ghana. A descriptive cross-sectional study with a multi-stage sampling technique was employed to select a total of 450 study respondents (expectant mothers), and a semi-structured questionnaire was used for the data collection. Respondents were interviewed using face-to-face interview technique. Majority (54.0%) of the respondents were aged between 25 and 35 years and the results were similar in both districts. Overall, 62.4% (281/450) of the respondents had at least Junior High level education, and 76.2% (343/450) were multigravida. Educational levels among respondents in the two areas were above 50.0% and considered relatively high. Respondents' general knowledge of hepatitis B infection and disease was 46.0% (208/450). However, there was a slight difference between the two districts (40.1% in Lawra District and 51.6% in Wa Municipality). The overall knowledge level on MTCT of viral hepatitis B among the respondents was 34.7% (156/450): the Wa Municipality recorded higher knowledge (43.3%) compared to 24.8% in Lawra District. The knowledge level of the expectant mothers on MTCT of viral hepatitis B is relatively low in Upper West Region, Ghana. Majority of the respondents had some form of formal education. The age, marital status, education, occupation, gravity and family setup were found to be associated with knowledge of Hepatitis B infection and MTCT. Thus, there is urgent need to intensify efforts of health staff to educate expectant mothers. In addition, home education and outreach activities should be intensified on HBV

  13. 46 CFR 52.05-15 - Heat treatment (modifies PW-10).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Heat treatment (modifies PW-10). 52.05-15 Section 52.05-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-15 Heat treatment (modifies PW-10). (a) Vessels and...

  14. 46 CFR 52.05-15 - Heat treatment (modifies PW-10).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Heat treatment (modifies PW-10). 52.05-15 Section 52.05-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-15 Heat treatment (modifies PW-10). (a) Vessels and...

  15. 46 CFR 52.05-15 - Heat treatment (modifies PW-10).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Heat treatment (modifies PW-10). 52.05-15 Section 52.05-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-15 Heat treatment (modifies PW-10). (a) Vessels and...

  16. 46 CFR 52.05-15 - Heat treatment (modifies PW-10).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Heat treatment (modifies PW-10). 52.05-15 Section 52.05-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-15 Heat treatment (modifies PW-10). (a) Vessels and...

  17. 46 CFR 52.05-15 - Heat treatment (modifies PW-10).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Heat treatment (modifies PW-10). 52.05-15 Section 52.05-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-15 Heat treatment (modifies PW-10). (a) Vessels and...

  18. M2-F2 Mated to B-52 Mothership on Ramp

    NASA Technical Reports Server (NTRS)

    1965-01-01

    A head-on view of the M2-F2 lifting body mounted on the wing pylon of its B-52 mothership in 1965. This was for a captive flight made the following month. The M2-F2 remained attached to the B-52 throughout the flight to test its on-board systems. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute

  19. 46 CFR 52.01-115 - Feedwater supply (modifies PG-61).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Feedwater supply (modifies PG-61). 52.01-115 Section 52.01-115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-115 Feedwater supply (modifies PG-61). Boiler feedwater supply must meet the requirements of PG-61 of section I of...

  20. 46 CFR 52.01-115 - Feedwater supply (modifies PG-61).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Feedwater supply (modifies PG-61). 52.01-115 Section 52.01-115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-115 Feedwater supply (modifies PG-61). Boiler feedwater supply must meet the requirements of PG-61 of section I of...

  1. 46 CFR 52.01-115 - Feedwater supply (modifies PG-61).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Feedwater supply (modifies PG-61). 52.01-115 Section 52.01-115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-115 Feedwater supply (modifies PG-61). Boiler feedwater supply must meet the requirements of PG-61 of section I of...

  2. 46 CFR 52.01-115 - Feedwater supply (modifies PG-61).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Feedwater supply (modifies PG-61). 52.01-115 Section 52.01-115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-115 Feedwater supply (modifies PG-61). Boiler feedwater supply must meet the requirements of PG-61 of section I of...

  3. 46 CFR 52.01-115 - Feedwater supply (modifies PG-61).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Feedwater supply (modifies PG-61). 52.01-115 Section 52.01-115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-115 Feedwater supply (modifies PG-61). Boiler feedwater supply must meet the requirements of PG-61 of section I of...

  4. 46 CFR 52.01-55 - Increase in maximum allowable working pressure.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Increase in maximum allowable working pressure. 52.01-55 Section 52.01-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-55 Increase in maximum allowable working pressure. (a) When...

  5. 46 CFR 52.01-55 - Increase in maximum allowable working pressure.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Increase in maximum allowable working pressure. 52.01-55 Section 52.01-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-55 Increase in maximum allowable working pressure. (a) When...

  6. 46 CFR 52.01-55 - Increase in maximum allowable working pressure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Increase in maximum allowable working pressure. 52.01-55 Section 52.01-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-55 Increase in maximum allowable working pressure. (a) When...

  7. 46 CFR 52.01-55 - Increase in maximum allowable working pressure.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Increase in maximum allowable working pressure. 52.01-55 Section 52.01-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-55 Increase in maximum allowable working pressure. (a) When...

  8. 46 CFR 52.01-55 - Increase in maximum allowable working pressure.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Increase in maximum allowable working pressure. 52.01-55 Section 52.01-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-55 Increase in maximum allowable working pressure. (a) When...

  9. Placental expression of asialoglycoprotein receptor associated with Hepatitis B virus transmission from mother to child.

    PubMed

    Vyas, Ashish Kumar; Ramakrishna, Usha; Sen, Bijoya; Islam, Mojahidul; Ramakrishna, Gayatri; Patra, Sharda; Rastogi, Archana; Sarin, Shiv Kumar; Trehanpati, Nirupma

    2018-04-30

    Asialoglycoprotein receptor expression on hepatocytes has been associated with endocytosis, binding and uptake of hepatitis B virus. The role of asialoglycoprotein receptor in hepatitis B virus vertical transmission and its expression on placenta has not yet been studied. Thirty-four HBsAg+ve and 13 healthy pregnant mothers along with their newborns were enrolled. The former were categorized into transmitting and non-transmitting mothers based on their newborns being hepatitis B surface antigen and hepatitis B virus DNA positive. Expression of asialoglycoprotein receptor and hepatitis B surface antigen in placenta and isoform of asialoglycoprotein receptor on dendritic cell in peripheral and cord blood dendritic cells were analysed using flowcytometry, immune histochemistry, immune florescence and qRT-PCR. Twelve HBsAg+ve mothers transmitted hepatitis B virus to their newborns whereas the rest (n = 22) did not. Hepatitis B virus-transmitting mothers showed increased expression of asialoglycoprotein receptor in trophoblasts of placenta. Immunofluorescence microscopy revealed colocalization of hepatitis B surface antigen and asialoglycoprotein receptor in placenta as well as in DCs of transmitting mothers. There was no significant difference in the expression of asialoglycoprotein receptor on peripheral blood mononuclear cells or chord blood mononuclear cells between the 2 groups. However, hepatitis B virus-transmitting mothers and their HBsAg+ve newborns showed increased mRNA levels of isoform of asialoglycoprotein receptor on dendritic cell in peripheral blood mononuclear cells. Hepatitis B virus-transmitting mothers and their HBsAg+ve newborns showed an increased expression of isoform of asialoglycoprotein receptor on dendritic cell on circulating dendritic cells compared to hepatitis B virus non-transmitting mothers and their negative newborns. This study revealed that increased expression of asialoglycoprotein receptor in placenta and colocalization with

  10. X-38 on B-52 Wing Pylon - View from Observation Window

    NASA Image and Video Library

    1997-11-19

    A unique, close-up view of the X-38 under the wing of NASA's B-52 mothership prior to launch of the lifting-body research vehicle. The photo was taken from the observation window of the B-52 bomber as it banked in flight.

  11. HLA-A, -B, and -DR zero-mismatched kidneys shipped to the University of Wisconsin, Madison, 1993-2006: superior graft survival despite longer preservation time.

    PubMed

    Burlingham, William J; Muñoz del Rio, Alejandro; Lorentzen, David; Sollinger, Hans W; Pirsch, John D; Jankowska-Gan, Ewa; D'Alessandro, Anthony

    2010-08-15

    To determine the impact at a single center of the United Network for Organ Sharing-mandated sharing program for human leukocyte antigen (HLA)-A/-B/-DR 0-mismatched (0MM) kidneys, we analyzed the results of 264 kidney transplants from 0MM distant donors between 1993 and 2006, with a follow-up through January 31, 2007. We compared these results with that of concurrent kidneys transplanted from HLA more than 0MM local donors and with shipped more than 0MM kidneys from "payback" donors. Despite a significantly longer preservation time, we found an 11% increase in 8-year graft survival (63% vs. 52%; P<0.003) of 0MM shipped versus locally procured, >0MM donor kidneys. Graft survival of 0MM shipped kidneys at 8 years was significantly better in nonsensitized (<20% panel reactive antibodies; 68% vs. 55%; P<0.0005) but not in sensitized (>or=20% panel reactive antibodies) recipients, who showed an early (2 years) but short-lived benefit. The benefit of receiving a HLA-A, -B, and -DR 0MM shipped kidney remained strong and statistically significant (0.71 relative risk of graft loss vs. local; P<0.02) when adjusted for 22 potentially confounding variables in a Cox proportional hazards analysis. The recent change in United Network for Organ Sharing policy restricting mandated sharing of 0MM kidneys to sensitized and pediatric recipients will give greater flexibility to the local organ procurement organization in allocating organs. However, the survival benefit to nonsensitized patients is real and long lasting and will be lost.

  12. [Serological and nutritional outcome of infants born to HIV positive mothers undergoing option B + therapy in Guédiawaye].

    PubMed

    Baptiste, Diouf Jean; Djibril, Diallo; Assane, Sylla; Ngagne, Mbaye; Baly, Ouattara; Ousmane, Ndiaye

    2016-01-01

    As part of its Plan to eliminate mother-to-child transmission of HIV, Senegal has adopted, since 2012, WHO's B + option, which consists of systematic triple therapy for HIV-positive pregnant women associated with breastfeeding and antiretroviral (ARV) prophylaxis for their infants. Our study aims to analyze the risks of mother-to-child transmission of HIV and the nutritional outcome of infants undergoing B + option. We conducted a descriptive, retrospective study at the King Baudouin health center in Guédiaway from 1 September 2012 to 30 April 2015. All infants whose mothers were on triple therapy, undergoing protected breastfeeding, ARV prophylaxis and serological test at 14th months were included in the study. The parameters studied were mother's age and serological profile, father's serological status, the sharing of the status within the couple, infant nourishing, infant ARV prophylaxis, nutritional status at 6 and 12 months and serological status of the infant at 14 months. Out of the 126 infants undergoing PMTCT program, 42 or 33.33% of infants following the B + guidelines were included in the study. The age of mothers ranged from 15 to 42 years, with an average age of 31 years. The majority of mothers (88.1%) carried type 1 virus and 11.9% carried type 2 virus; 20 couples (47.62%) were sero-concordant, 14 were serodifferent, while the serological status was unknown or not investigated in 8 fathers (19.05%). A significant difference between fathers' serological profile and the sharing status (p <0.05) was found. The majority of infants (88.1%) were born at term via vaginal delivery (95.2%), with an average birth weight of 2880 grams. In relation to prophylaxis, the majority of infants received prophylactic monotherapy, 27 (64.28%) received NVP, 4 (9.52%) received AZT, while 11 (26.19%) received triple combination of AZT + 3TC + NVP. The AME was effective in 80.9% of infants and weaning began at 12 months in 80.9% of infants. In relation to nutritional status

  13. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  14. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  15. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  16. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  17. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  18. 46 CFR 52.25-3 - Feedwater heaters (modifies PFH-1).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Feedwater heaters (modifies PFH-1). 52.25-3 Section 52.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-3 Feedwater heaters (modifies PFH-1). In addition to the requirements in PFH-1 of section I of the ASME Boiler and...

  19. 46 CFR 52.25-3 - Feedwater heaters (modifies PFH-1).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Feedwater heaters (modifies PFH-1). 52.25-3 Section 52.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-3 Feedwater heaters (modifies PFH-1). In addition to the requirements in PFH-1 of section I of the ASME Boiler and...

  20. 46 CFR 52.25-3 - Feedwater heaters (modifies PFH-1).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Feedwater heaters (modifies PFH-1). 52.25-3 Section 52.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-3 Feedwater heaters (modifies PFH-1). In addition to the requirements in PFH-1 of section I of the ASME Boiler and...

  1. 46 CFR 52.25-3 - Feedwater heaters (modifies PFH-1).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Feedwater heaters (modifies PFH-1). 52.25-3 Section 52.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-3 Feedwater heaters (modifies PFH-1). In addition to the requirements in PFH-1 of section I of the ASME Boiler and...

  2. 46 CFR 52.25-3 - Feedwater heaters (modifies PFH-1).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Feedwater heaters (modifies PFH-1). 52.25-3 Section 52.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-3 Feedwater heaters (modifies PFH-1). In addition to the requirements in PFH-1 of section I of the ASME Boiler and...

  3. X-15 on Lakebed after Landing with B-52 Mothership Flyover

    NASA Technical Reports Server (NTRS)

    1961-01-01

    As crew members secure the X-15 rocket-powered aircraft after a research flight, the B-52 mothership used for launching this unique aircraft does a low fly-by overhead. The X-15s made a total of 199 flights over a period of nearly 10 years -- 1959 to 1968 -- and set unofficial world speed and altitude records of 4,520 mph (Mach 6.7) and 354,200. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo piloted spaceflight programs, and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable

  4. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  5. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  6. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  7. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  8. 48 CFR 52.247-34 - F.o.b. Destination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination. 52.247....o.b. Destination. As prescribed in 47.303-6(c), insert the following clause: F.o.b. Destination (JAN 1991) (a) The term f.o.b. destination, as used in this clause, means— (1) Free of expense to the...

  9. HiMAT Subscale Research Vehicle Mated to B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The Highly Maneuverable Aircraft Technology (HiMAT) research vehicle is shown here mated to a wing pylon on NASA's B-52 mothership aircraft. The HiMAT was a technology demonstrator to test structures and configurations for advanced fighter concepts. Over the course of more than 40 years, the B-52 proved a valuable workhorse for NASA's Dryden Flight Research Center (under various names), launching a wide variety of vehicles and conducting numerous other research flights. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for

  10. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin. 52.247-29....o.b. Origin. As prescribed in 47.303-1(c), insert the following clause: F.o.b. Origin (FEB 2006) (a) The term f.o.b. origin, as used in this clause, means free of expense to the Government delivered— (1...

  11. 42 CFR 52b.12 - What are the minimum requirements of construction and equipment?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the minimum requirements of construction and equipment? 52b.12 Section 52b.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.12 What are the minimum...

  12. Ro52-mediated Monoubiquitination of IKKβ Down-regulates NF-κB Signalling

    PubMed Central

    Wada, Keiji; Niida, Motoko; Tanaka, Makoto; Kamitani, Tetsu

    2009-01-01

    Upon activation, NF-κB translocates into the nucleus and initiates biological events. This NF-κB signalling is mainly regulated by the protein kinase IKKβ. Early in this signalling pathway, IKKβ is phosphorylated for activation by several factors, such as pro-inflammatory cytokines and the Tax oncoprotein of HTLV-1. In cells infected by HTLV-1, IKKβ is persistently phosphorylated and conjugated with monoubiquitin due to Tax expression. Although this Tax-induced monoubiquitination appears to be an important regulation system for IKKβ, how the monoubiquitination occurs is unknown and its role in NF-κB signalling is still unclear. Here, we show that an E3-ubiquitin ligase Ro52 interacts weakly with wild-type IKKβ but strongly with a phosphomimetic mutant IKKβ to conjugate monoubiquitin in cooperation with an E2-ubiquitin-conjugating enzyme UbcH5B. These results suggest that the Tax-induced phosphorylation of IKKβ causes an interaction with Ro52 for the subsequent monoubiquitination. NF-κB reporter assays have shown that the IKKβ activity is suppressed by wild-type Ro52, but not by its inactive mutant. In addition, monoubiquitin fusion of IKKβ reduced its activity for NF-κB signalling. We also found that Ro52 dramatically reduces the level of Tax. These results suggest that Ro52 down-regulates Tax-induced NF-κB signalling by monoubiquitinating IKKβ and by reducing the level of Tax. PMID:19675099

  13. [A new human leukocyte antigen class I allele, HLA- B*52:11].

    PubMed

    Li, Xiao-feng; Zhang, Xu; Zhang, Kun-lian; Chen, Yang; Liu, Xian-zhi; Li, Jian-ping

    2011-12-01

    To identify and confirm a novel HLA allele. A new human leukocyte antigen class I allele was found during routine HLA genotyping by polymerase chain reaction-sequence specific oligonucleotide probes (PCR-SSOP) and sequencing-based typing (SBT). The novel HLA-B*52 allele was identical to B*52:01:01 with an exception of one base substitution at position 583 of exon 3 where a C was changed to T resulting in codon 195 changed from CAC(H) to TAC(Y). A new HLA class I allele, B*52:11, is identified, and is named officially by the WHO Nomenclature Committee.

  14. 48 CFR 242.1403 - Shipping documents covering f.o.b. origin shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Shipping documents covering f.o.b. origin shipments. 242.1403 Section 242.1403 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT...

  15. 46 CFR 52.05-30 - Minimum requirements for attachment welds (modifies PW-16).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Minimum requirements for attachment welds (modifies PW-16). 52.05-30 Section 52.05-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-30 Minimum...

  16. 46 CFR 52.05-30 - Minimum requirements for attachment welds (modifies PW-16).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Minimum requirements for attachment welds (modifies PW-16). 52.05-30 Section 52.05-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-30 Minimum...

  17. 46 CFR 52.05-30 - Minimum requirements for attachment welds (modifies PW-16).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Minimum requirements for attachment welds (modifies PW-16). 52.05-30 Section 52.05-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-30 Minimum...

  18. 46 CFR 52.05-30 - Minimum requirements for attachment welds (modifies PW-16).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Minimum requirements for attachment welds (modifies PW-16). 52.05-30 Section 52.05-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-30 Minimum...

  19. 46 CFR 52.05-30 - Minimum requirements for attachment welds (modifies PW-16).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Minimum requirements for attachment welds (modifies PW-16). 52.05-30 Section 52.05-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-30 Minimum...

  20. 46 CFR 111.52-5 - Systems 1500 kilowatts or above.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Systems 1500 kilowatts or above. 111.52-5 Section 111.52-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC... procedure for utility or industrial applications. [CGD 94-108, 61 FR 28279, June 4, 1996, as amended by USCG...

  1. 46 CFR 111.52-5 - Systems 1500 kilowatts or above.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Systems 1500 kilowatts or above. 111.52-5 Section 111.52-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC... procedure for utility or industrial applications. [CGD 94-108, 61 FR 28279, June 4, 1996, as amended by USCG...

  2. 46 CFR 111.52-5 - Systems 1500 kilowatts or above.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Systems 1500 kilowatts or above. 111.52-5 Section 111.52-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC... procedure for utility or industrial applications. [CGD 94-108, 61 FR 28279, June 4, 1996, as amended by USCG...

  3. 46 CFR 111.52-5 - Systems 1500 kilowatts or above.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Systems 1500 kilowatts or above. 111.52-5 Section 111.52-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC... procedure for utility or industrial applications. [CGD 94-108, 61 FR 28279, June 4, 1996, as amended by USCG...

  4. 46 CFR 111.52-5 - Systems 1500 kilowatts or above.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Systems 1500 kilowatts or above. 111.52-5 Section 111.52-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC... procedure for utility or industrial applications. [CGD 94-108, 61 FR 28279, June 4, 1996, as amended by USCG...

  5. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  6. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  7. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  8. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  9. 46 CFR 52.15-1 - General (modifies PWT-1 through PWT-15).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false General (modifies PWT-1 through PWT-15). 52.15-1 Section 52.15-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-1 General (modifies PWT-1 through PWT-15). Watertube boilers and parts thereof shall be as...

  10. 46 CFR 52.15-1 - General (modifies PWT-1 through PWT-15).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false General (modifies PWT-1 through PWT-15). 52.15-1 Section 52.15-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-1 General (modifies PWT-1 through PWT-15). Watertube boilers and parts thereof shall be as...

  11. 46 CFR 52.15-1 - General (modifies PWT-1 through PWT-15).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false General (modifies PWT-1 through PWT-15). 52.15-1 Section 52.15-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-1 General (modifies PWT-1 through PWT-15). Watertube boilers and parts thereof shall be as...

  12. 46 CFR 52.15-1 - General (modifies PWT-1 through PWT-15).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false General (modifies PWT-1 through PWT-15). 52.15-1 Section 52.15-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-1 General (modifies PWT-1 through PWT-15). Watertube boilers and parts thereof shall be as...

  13. 46 CFR 52.15-1 - General (modifies PWT-1 through PWT-15).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false General (modifies PWT-1 through PWT-15). 52.15-1 Section 52.15-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-1 General (modifies PWT-1 through PWT-15). Watertube boilers and parts thereof shall be as...

  14. 46 CFR 52.01-50 - Fusible plugs (modifies A-19 through A-21).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Fusible plugs (modifies A-19 through A-21). 52.01-50 Section 52.01-50 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-50 Fusible plugs (modifies A-19 through A-21). (a) All...

  15. 46 CFR 52.01-50 - Fusible plugs (modifies A-19 through A-21).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Fusible plugs (modifies A-19 through A-21). 52.01-50 Section 52.01-50 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-50 Fusible plugs (modifies A-19 through A-21). (a) All...

  16. 46 CFR 52.01-50 - Fusible plugs (modifies A-19 through A-21).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Fusible plugs (modifies A-19 through A-21). 52.01-50 Section 52.01-50 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-50 Fusible plugs (modifies A-19 through A-21). (a) All...

  17. 46 CFR 52.01-50 - Fusible plugs (modifies A-19 through A-21).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Fusible plugs (modifies A-19 through A-21). 52.01-50 Section 52.01-50 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-50 Fusible plugs (modifies A-19 through A-21). (a) All...

  18. 46 CFR 52.20-1 - General (modifies PFT-1 through PFT-49).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false General (modifies PFT-1 through PFT-49). 52.20-1 Section 52.20-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-1 General (modifies PFT-1 through PFT-49). Firetube boilers and parts thereof shall be as indicated...

  19. 46 CFR 52.20-1 - General (modifies PFT-1 through PFT-49).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false General (modifies PFT-1 through PFT-49). 52.20-1 Section 52.20-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-1 General (modifies PFT-1 through PFT-49). Firetube boilers and parts thereof shall be as indicated...

  20. 46 CFR 52.20-1 - General (modifies PFT-1 through PFT-49).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false General (modifies PFT-1 through PFT-49). 52.20-1 Section 52.20-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-1 General (modifies PFT-1 through PFT-49). Firetube boilers and parts thereof shall be as indicated...

  1. 46 CFR 52.20-1 - General (modifies PFT-1 through PFT-49).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false General (modifies PFT-1 through PFT-49). 52.20-1 Section 52.20-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-1 General (modifies PFT-1 through PFT-49). Firetube boilers and parts thereof shall be as indicated...

  2. 46 CFR 52.20-1 - General (modifies PFT-1 through PFT-49).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false General (modifies PFT-1 through PFT-49). 52.20-1 Section 52.20-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-1 General (modifies PFT-1 through PFT-49). Firetube boilers and parts thereof shall be as indicated...

  3. 46 CFR 52.01-90 - Materials (modifies PG-5 through PG-13).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Materials (modifies PG-5 through PG-13). 52.01-90 Section 52.01-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-90 Materials (modifies PG-5 through PG-13). (a) Material subject to stress due to pressure must conform to...

  4. 46 CFR 52.01-90 - Materials (modifies PG-5 through PG-13).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Materials (modifies PG-5 through PG-13). 52.01-90 Section 52.01-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-90 Materials (modifies PG-5 through PG-13). (a) Material subject to stress due to pressure must conform to...

  5. 46 CFR 52.01-90 - Materials (modifies PG-5 through PG-13).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Materials (modifies PG-5 through PG-13). 52.01-90 Section 52.01-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-90 Materials (modifies PG-5 through PG-13). (a) Material subject to stress due to pressure must conform to...

  6. M2-F3 In-flight Launch from B-52

    NASA Technical Reports Server (NTRS)

    1971-01-01

    This photo shows the M2-F3 Lifting Body being launched from NASA's B-52 mothership at the NASA Flight Research Center (FRC--now the Dryden Flight Research Center), Edwards, California. A fleet of lifting bodies flown at the FRC from 1963 to l975 demonstrated the ability of pilots to maneuver and safely land a wingless vehicle designed to fly back to Earth from space and be landed like an aircraft at a pre-determined site. Early flight testing of the M2-F1 and M2-F2 lifting body reentry configurations had validated the concept of piloted lifting body reentry from space. When the M2-F2 crashed on May 10, 1967, valuable information had already been obtained and was contributing to new designs. NASA pilots said the M2-F2 had lateral control problems, so when the M2-F2 was rebuilt at Northrop and redesignated the M2-F3, it was modified with an additional third vertical fin -- centered between the tip fins -- to improve control characteristics. First flight of the M2-F3, with NASA pilot Bill Dana at the controls, was June 2, 1970. The modified vehicle exhibited much better lateral stability and control characteristics than before, and only three glide flights were necessary before the first powered flight on Nov. 25, 1970. Over the next 26 missions, the M2-F3 reached a top speed of l,064 mph (Mach 1.6). Highest altitude reached by vehicle was 7l,500 feet on Dec. 20, 1972, the date of its last flight, with NASA pilot John Manke at the controls. NASA donated The M2-F3 vehicle to the Smithsonian Institute in December 1973. It is currently hanging in the Air and Space Museum along with the X-15 aircraft number 1, which was its hangar partner from 1965 to 1969. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most

  7. Analysis of radiation exposure for naval units of Operation Crossroads. Volume 3. (Appendix B) support ships. Technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weitz, R.; Thomas, C.; Klemm, J.

    1982-03-03

    External radiation doses are reconstructed for crews of support and target ships of Joint Task Force One at Operation CROSSROADS, 1946. Volume I describes the reconstruction methodology, which consists of modeling the radiation environment, to include the radioactivity of lagoon water, target ships, and support ship contamination; retracing ship paths through this environment; and calculating the doses to shipboard personnel. The USS RECLAIMER, a support ship, is selected as a representative ship to demonstrate this methodology. Doses for all other ships are summarized. Volume II (Appendix A) details the results for target ship personnel. Volume III (Appendix B) details themore » results for support ship personnel. Calculated doses for more than 36,000 personnel aboard support ships while at Bikini range from zero to 1.7 rem. Of those approximately 34,000 are less than 0.5 rem. From the models provided, doses due to target ship reboarding and doses accrued after departure from Bikini can be calculated, based on the individual circumstances of exposure.« less

  8. 46 CFR 52.01-35 - Auxiliary, donkey, fired thermal fluid heater, and heating boilers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Auxiliary, donkey, fired thermal fluid heater, and heating boilers. 52.01-35 Section 52.01-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-35 Auxiliary, donkey, fired thermal...

  9. 46 CFR 52.01-35 - Auxiliary, donkey, fired thermal fluid heater, and heating boilers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Auxiliary, donkey, fired thermal fluid heater, and heating boilers. 52.01-35 Section 52.01-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-35 Auxiliary, donkey, fired thermal...

  10. 46 CFR 52.01-35 - Auxiliary, donkey, fired thermal fluid heater, and heating boilers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Auxiliary, donkey, fired thermal fluid heater, and heating boilers. 52.01-35 Section 52.01-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-35 Auxiliary, donkey, fired thermal...

  11. 46 CFR 52.01-35 - Auxiliary, donkey, fired thermal fluid heater, and heating boilers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Auxiliary, donkey, fired thermal fluid heater, and heating boilers. 52.01-35 Section 52.01-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-35 Auxiliary, donkey, fired thermal...

  12. Abraham Lincoln's marfanoid mother: the earliest known case of multiple endocrine neoplasia type 2B?

    PubMed

    Sotos, John G

    2012-07-01

    The nature and cause of President Abraham Lincoln's unusual physical features have long been debated, with the greatest attention directed at two monogenic disorders of the transforming growth factor β system: Marfan syndrome and multiple endocrine neoplasia type 2B. The present report examines newly discovered phenotypic information about Lincoln's biological mother, Nancy Hanks Lincoln, and concludes that (a) Lincoln's mother was skeletally marfanoid, (b) the President and his mother were highly concordant for the presence of numerous facial features found in various transforming growth factor β disorders, and (c) Lincoln's mother, like her son, had hypotonic skeletal muscles, resulting in myopathic facies and 'pseudodepression'. These conclusions establish that mother and son had the same monogenic autosomal dominant marfanoid disorder. A description of Nancy Hanks Lincoln as coarse-featured, and a little-known statement that a wasting disease contributed to her death at age 34, lends support to the multiple endocrine neoplasia type 2B hypothesis.

  13. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25-5 Section 52.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable...

  14. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25-5 Section 52.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable...

  15. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25-5 Section 52.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable...

  16. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25-5 Section 52.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable...

  17. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25-5 Section 52.25-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable...

  18. 33 CFR 117.753 - Ship Channel, Great Egg Harbor Bay.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Ship Channel, Great Egg Harbor... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements New Jersey § 117.753 Ship Channel, Great Egg Harbor Bay. The draw of the S52 (Ship Channel) bridge, mile 0.5 between Somers Point and Ocean...

  19. 33 CFR 117.753 - Ship Channel, Great Egg Harbor Bay.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Ship Channel, Great Egg Harbor... SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements New Jersey § 117.753 Ship Channel, Great Egg Harbor Bay. The draw of the S52 (Ship Channel) bridge, mile 0.5 between Somers Point and Ocean...

  20. M2-F2 Lifting Body being Carried Aloft by B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The M2-F2 Lifting Body is shown here being carried aloft by the Air Force's B-52 (tail number 003) prior to a research launch. The success of Dryden's 'homebuilt' M2-F1 program led to NASA's development and construction of two heavyweight lifting bodies--the M2-F2 and the HL-10, both built by the Northrop Corporation. The 'M' refers to 'manned' and 'F' refers to 'flight' version. 'HL' comes from 'horizontal landing.' The first flight of the M2-F2--which looked much like the 'F1'--was on July 12, 1966. Milt Thompson was the pilot. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable

  1. 46 CFR 52.20-17 - Opening between boiler and safety valve (modifies PFT-44).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Opening between boiler and safety valve (modifies PFT-44). 52.20-17 Section 52.20-17 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-17 Opening between boiler and safety valve...

  2. 46 CFR 52.20-17 - Opening between boiler and safety valve (modifies PFT-44).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Opening between boiler and safety valve (modifies PFT-44). 52.20-17 Section 52.20-17 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-17 Opening between boiler and safety valve...

  3. 46 CFR 52.20-17 - Opening between boiler and safety valve (modifies PFT-44).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Opening between boiler and safety valve (modifies PFT-44). 52.20-17 Section 52.20-17 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-17 Opening between boiler and safety valve...

  4. 46 CFR 52.20-17 - Opening between boiler and safety valve (modifies PFT-44).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Opening between boiler and safety valve (modifies PFT-44). 52.20-17 Section 52.20-17 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-17 Opening between boiler and safety valve...

  5. 46 CFR 52.20-17 - Opening between boiler and safety valve (modifies PFT-44).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Opening between boiler and safety valve (modifies PFT-44). 52.20-17 Section 52.20-17 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Firetube Boilers § 52.20-17 Opening between boiler and safety valve...

  6. 46 CFR 52.15-5 - Tube connections (modifies PWT-9 and PWT-11).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Tube connections (modifies PWT-9 and PWT-11). 52.15-5 Section 52.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-5 Tube connections (modifies PWT-9 and PWT-11). (a) Tubes, pipe and nipples shall be attached...

  7. 46 CFR 52.15-5 - Tube connections (modifies PWT-9 and PWT-11).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Tube connections (modifies PWT-9 and PWT-11). 52.15-5 Section 52.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-5 Tube connections (modifies PWT-9 and PWT-11). (a) Tubes, pipe and nipples shall be attached...

  8. 46 CFR 52.15-5 - Tube connections (modifies PWT-9 and PWT-11).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Tube connections (modifies PWT-9 and PWT-11). 52.15-5 Section 52.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-5 Tube connections (modifies PWT-9 and PWT-11). (a) Tubes, pipe and nipples shall be attached...

  9. 46 CFR 52.15-5 - Tube connections (modifies PWT-9 and PWT-11).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Tube connections (modifies PWT-9 and PWT-11). 52.15-5 Section 52.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-5 Tube connections (modifies PWT-9 and PWT-11). (a) Tubes, pipe and nipples shall be attached...

  10. 46 CFR 52.15-5 - Tube connections (modifies PWT-9 and PWT-11).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Tube connections (modifies PWT-9 and PWT-11). 52.15-5 Section 52.15-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Watertube Boilers § 52.15-5 Tube connections (modifies PWT-9 and PWT-11). (a) Tubes, pipe and nipples shall be attached...

  11. The Inositol Phosphatase SHIP-1 Inhibits NOD2-Induced NF-κB Activation by Disturbing the Interaction of XIAP with RIP2

    PubMed Central

    Condé, Claude; Rambout, Xavier; Lebrun, Marielle; Lecat, Aurore; Di Valentin, Emmanuel; Dequiedt, Franck; Piette, Jacques

    2012-01-01

    SHIP-1 is an inositol phosphatase predominantly expressed in hematopoietic cells. Over the ten past years, SHIP-1 has been described as an important regulator of immune functions. Here, we characterize a new inhibitory function for SHIP-1 in NOD2 signaling. NOD2 is a crucial cytoplasmic bacterial sensor that activates proinflammatory and antimicrobial responses upon bacterial invasion. We observed that SHIP-1 decreases NOD2-induced NF-κB activation in macrophages. This negative regulation relies on its interaction with XIAP. Indeed, we observed that XIAP is an essential mediator of the NOD2 signaling pathway that enables proper NF-κB activation in macrophages. Upon NOD2 activation, SHIP-1 C-terminal proline rich domain (PRD) interacts with XIAP, thereby disturbing the interaction between XIAP and RIP2 in order to decrease NF-κB signaling. PMID:22815893

  12. 46 CFR 52.05-45 - Circumferential joints in pipes, tubes and headers (modifies PW-41).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Circumferential joints in pipes, tubes and headers (modifies PW-41). 52.05-45 Section 52.05-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-45...

  13. 46 CFR 52.05-45 - Circumferential joints in pipes, tubes and headers (modifies PW-41).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Circumferential joints in pipes, tubes and headers (modifies PW-41). 52.05-45 Section 52.05-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-45...

  14. 46 CFR 52.05-45 - Circumferential joints in pipes, tubes and headers (modifies PW-41).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Circumferential joints in pipes, tubes and headers (modifies PW-41). 52.05-45 Section 52.05-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-45...

  15. 46 CFR 52.05-45 - Circumferential joints in pipes, tubes and headers (modifies PW-41).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Circumferential joints in pipes, tubes and headers (modifies PW-41). 52.05-45 Section 52.05-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-45...

  16. 46 CFR 52.05-45 - Circumferential joints in pipes, tubes and headers (modifies PW-41).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Circumferential joints in pipes, tubes and headers (modifies PW-41). 52.05-45 Section 52.05-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-45...

  17. An Analysis of Chronic Personnel Shortages in the B-52 Radar Navigator Career Field

    DTIC Science & Technology

    1987-03-01

    Weapon System Trainer - The new simulators for the B-52 located on some of the B-52 bases. Due to the complexity of the simulators, they have a small ...navigators crosstraining to these are lost to the B-52 career field. 21 ASTRA Every year a small number of radar navigators are chosen to attend one yerc at...this case, though, it turned up a small problem initially. The separation rates were obtained from Headquarters SAC (10), but did not include the number

  18. 46 CFR 52.01-135 - Inspection and tests (modifies PG-90 through PG-100).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Inspection and tests (modifies PG-90 through PG-100). 52.01-135 Section 52.01-135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-135 Inspection and tests (modifies PG-90 through PG-100). (a) Requirements. Inspection and test...

  19. 46 CFR 52.01-140 - Certification by stamping (modifies PG-104 through PG-113).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Certification by stamping (modifies PG-104 through PG-113). 52.01-140 Section 52.01-140 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-140 Certification by stamping (modifies PG-104 through PG-113). (a) All boilers built in...

  20. 46 CFR 52.01-135 - Inspection and tests (modifies PG-90 through PG-100).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Inspection and tests (modifies PG-90 through PG-100). 52.01-135 Section 52.01-135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-135 Inspection and tests (modifies PG-90 through PG-100). (a) Requirements. Inspection and test...

  1. 46 CFR 52.01-140 - Certification by stamping (modifies PG-104 through PG-113).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Certification by stamping (modifies PG-104 through PG-113). 52.01-140 Section 52.01-140 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-140 Certification by stamping (modifies PG-104 through PG-113). (a) All boilers built in...

  2. 46 CFR 52.01-140 - Certification by stamping (modifies PG-104 through PG-113).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Certification by stamping (modifies PG-104 through PG-113). 52.01-140 Section 52.01-140 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-140 Certification by stamping (modifies PG-104 through PG-113). (a) All boilers built in...

  3. 46 CFR 52.01-140 - Certification by stamping (modifies PG-104 through PG-113).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Certification by stamping (modifies PG-104 through PG-113). 52.01-140 Section 52.01-140 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-140 Certification by stamping (modifies PG-104 through PG-113). (a) All boilers built in...

  4. 46 CFR 52.01-135 - Inspection and tests (modifies PG-90 through PG-100).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Inspection and tests (modifies PG-90 through PG-100). 52.01-135 Section 52.01-135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-135 Inspection and tests (modifies PG-90 through PG-100). (a) Requirements. Inspection and test...

  5. 46 CFR 52.01-140 - Certification by stamping (modifies PG-104 through PG-113).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Certification by stamping (modifies PG-104 through PG-113). 52.01-140 Section 52.01-140 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-140 Certification by stamping (modifies PG-104 through PG-113). (a) All boilers built in...

  6. 46 CFR 52.01-135 - Inspection and tests (modifies PG-90 through PG-100).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Inspection and tests (modifies PG-90 through PG-100). 52.01-135 Section 52.01-135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-135 Inspection and tests (modifies PG-90 through PG-100). (a) Requirements. Inspection and test...

  7. Antibody-Mediated Complement C3b/iC3b Binding to Group B Streptococcus in Paired Mother and Baby Serum Samples in a Refugee Population on the Thailand-Myanmar Border

    PubMed Central

    Herbert, Jenny; Thomas, Stephen; Brookes, Charlotte; Turner, Claudia; Turner, Paul; Nosten, Francois; Le Doare, Kirsty; Hudson, Michael; Heath, Paul T.; Gorringe, Andrew

    2015-01-01

    Streptococcus agalactiae (group B streptococcus [GBS]) is the leading cause of neonatal sepsis and meningitis. In this study, we determined antibody-mediated deposition of complement C3b/iC3b onto the bacterial cell surface of GBS serotypes Ia, Ib, II, III, and V. This was determined for 520 mother and umbilical cord serum sample pairs obtained at the time of birth from a population on the Thailand-Myanmar border. Antibody-mediated deposition of complement C3b/iC3b was detected to at least one serotype in 91% of mothers, despite a known carriage rate in this population of only 12%. Antibody-mediated C3b/iC3b deposition corresponded to known carriage rates, with the highest levels of complement deposition observed onto the most prevalent serotype (serotype II) followed by serotypes Ia, III, V, and Ib. Finally, neonates born to mothers carrying serotype II GBS at the time of birth showed higher antibody-mediated C3b/iC3b deposition against serotype II GBS than neonates born to mothers with no serotype II carriage. Assessment of antibody-mediated C3b/iC3b deposition against GBS may provide insights into the seroepidemiology of anti-GBS antibodies in mothers and infants in different populations. PMID:25589553

  8. B-52/Pegasus with X-43A departing on first captive flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  9. B-52/Pegasus with X-43A in flight over Pacific Ocean.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  10. Close view of B-52/Pegasus with X-43A in flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  11. 48 CFR 52.247-45 - F.o.b. Origin and/or F.o.b. Destination Evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin and/or F.o.b... Clauses 52.247-45 F.o.b. Origin and/or F.o.b. Destination Evaluation. As prescribed in 47.305-2(b), insert the following provision in solicitations when offers are solicited on the basis of both f.o.b. origin...

  12. RelB is required for Peyer’s patch development: differential regulation of p52–RelB by lymphotoxin and TNF

    PubMed Central

    Yilmaz, Z.Buket; Weih, Debra S.; Sivakumar, Vallabhapurapu; Weih, Falk

    2003-01-01

    Targeted disruption of the Rel/NF-κB family members NF-κB2, encoding p100/p52, and RelB in mice results in anatomical defects of secondary lymphoid tissues. Here, we report that development of Peyer’s patch (PP)-organizing centers is impaired in both NF-κB2- and RelB-deficient animals. IL-7-induced expression of lymphotoxin (LT) in intestinal cells, a crucial step in PP development, is not impaired in RelB-deficient embryos. LTβ receptor (LTβR)-deficient mice also lack PPs, and we demonstrate that LTβR signaling induces p52–RelB and classical p50–RelA heterodimers, while tumor necrosis factor (TNF) activates only RelA. LTβR-induced binding of p52–RelB requires the degradation of the inhibitory p52 precursor, p100, which is mediated by the NF-κB-inducing kinase (NIK) and the IκB kinase (IKK) complex subunit IKKα, but not IKKβ or IKKγ. Activation of RelA requires all three IKK subunits, but is independent of NIK. Finally, we show that TNF increases p100 levels, resulting in the specific inhibition of RelB DNA binding via the C-terminus of p100. Our data indicate an important role of p52–RelB heterodimers in lymphoid organ development downstream of LTβR, NIK and IKKα. PMID:12505990

  13. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  14. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  15. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  16. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  17. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  18. [Prevalence of occult hepatitis B virus infection and its phylogenetic features among mother-teenager pairs].

    PubMed

    Dong, Xiao-lian; Yao, Qing-qing; Wang, Xue-cai; Xu, Hai-tao; Wang, Xiao-li; Chen, Sheng-yu; Tang, Zhi-feng; Zheng, Ying-Jie

    2013-03-01

    Prevalence of occult hepatitis B virus (HBV) infection (OBI) was investigated in a paired mother-teenager population and HBV S gene variation including overt and occult HBV, was determined. A follow-up study based on an initial survey of 135 mother-teenager pairs was carried out through collection of questionnaires and blood samples HBsAg were detected by ELISA method, viral load by PCR amplification and HBV S gene by phylogenetic analysis. 102 pairs of subjects were followed-up. Blood samples from 94 mothers and 101 children were collected. OBI prevalence in mothers was 10.0% (6/60), significantly higher than 2.0% (2/101) in teenagers. Medians of viral load were 399.9 IU/ml and 247.6 IU/ml in overt and occult HBV strains, but without significant difference. 1 occult HBV strain belonged to genotype B with serotype adw while the other 7 were genotype C with serotype adr. 15 of the overt HBV strains belonged to genotype B with serotype adw and the other 8 were genotype C with serotype adr. Proportions of genotype-C strains were significantly higher in occult HBV strains than in overt HBV strains. OBI was seen in teenage-mother population.

  19. Cockpit resource management skills enhance combat mission performance in a B-52 simulator

    NASA Technical Reports Server (NTRS)

    Povenmire, H. Kingsley; Rockway, Marty R.; Bunecke, Joseph L.; Patton, Mark W.

    1989-01-01

    A cockpit resource management (CRM) program for mission-ready B-52 aircrew is developed. The relationship between CRM performance and combat mission performance is studied. The performances of six crew members flying a simulated high workload mission in a B-52 weapon system trainer are evaluated. The data reveal that CRM performance enhances tactical maneuvers and bombing accuracy.

  20. 46 CFR 52.25-10 - Organic fluid vaporizer generators (modifies PVG-1 through PVG-12).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). 52.25-10 Section 52.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-10 Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). (a) Organic...

  1. 46 CFR 52.01-145 - Manufacturers' data report forms (modifies PG-112 and PG-113).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Manufacturers' data report forms (modifies PG-112 and PG-113). 52.01-145 Section 52.01-145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-145 Manufacturers' data report forms (modifies PG-112 and PG-113). The manufacturers'...

  2. 46 CFR 52.01-145 - Manufacturers' data report forms (modifies PG-112 and PG-113).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Manufacturers' data report forms (modifies PG-112 and PG-113). 52.01-145 Section 52.01-145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-145 Manufacturers' data report forms (modifies PG-112 and PG-113). The manufacturers'...

  3. 46 CFR 52.01-145 - Manufacturers' data report forms (modifies PG-112 and PG-113).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Manufacturers' data report forms (modifies PG-112 and PG-113). 52.01-145 Section 52.01-145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-145 Manufacturers' data report forms (modifies PG-112 and PG-113). The manufacturers'...

  4. 46 CFR 52.25-10 - Organic fluid vaporizer generators (modifies PVG-1 through PVG-12).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). 52.25-10 Section 52.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-10 Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). (a) Organic...

  5. 46 CFR 52.25-10 - Organic fluid vaporizer generators (modifies PVG-1 through PVG-12).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). 52.25-10 Section 52.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-10 Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). (a) Organic...

  6. 46 CFR 52.25-10 - Organic fluid vaporizer generators (modifies PVG-1 through PVG-12).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). 52.25-10 Section 52.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-10 Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). (a) Organic...

  7. 46 CFR 52.01-145 - Manufacturers' data report forms (modifies PG-112 and PG-113).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Manufacturers' data report forms (modifies PG-112 and PG-113). 52.01-145 Section 52.01-145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-145 Manufacturers' data report forms (modifies PG-112 and PG-113). The manufacturers'...

  8. 46 CFR 52.25-10 - Organic fluid vaporizer generators (modifies PVG-1 through PVG-12).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). 52.25-10 Section 52.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Other Boiler Types § 52.25-10 Organic fluid vaporizer generators (modifies PVG-1 through PVG-12). (a) Organic...

  9. 46 CFR 52.01-145 - Manufacturers' data report forms (modifies PG-112 and PG-113).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Manufacturers' data report forms (modifies PG-112 and PG-113). 52.01-145 Section 52.01-145 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-145 Manufacturers' data report forms (modifies PG-112 and PG-113). The manufacturers'...

  10. 46 CFR 52.05-20 - Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1). 52.05-20 Section 52.05-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-20...

  11. 46 CFR 52.05-20 - Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1). 52.05-20 Section 52.05-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-20...

  12. 46 CFR 52.05-20 - Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1). 52.05-20 Section 52.05-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-20...

  13. 46 CFR 52.05-20 - Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1). 52.05-20 Section 52.05-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-20...

  14. 46 CFR 52.05-20 - Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Radiographic and ultrasonic examination (modifies PW-11 and PW-41.1). 52.05-20 Section 52.05-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS Requirements for Boilers Fabricated by Welding § 52.05-20...

  15. Routine HLA-B genotyping with PCR-sequence-specific oligonucleotides detects a B*52 variant (B*5206).

    PubMed

    Hoelsch, K; Lenggeler, I; Pfannes, W; Knabe, H; Klein, H-G; Woelpl, A

    2005-05-01

    A new human leukocyte antigen (HLA)-B allele was found during routine typing of samples for a German unrelated bone marrow donor registry, the "Aktion Knochenmarkspende Bayern". After first interpretation of data of two independent low-resolution sequence-specific oligonucleotide typing tests, a B*51 variant was suggested. Further analysis via sequence-based typing identified the sequence as new B*52 allele. This new allele officially assigned as B*5206 differs from HLA-B*520102 by one nucleotide exchange in exon 2. The mutation is located at nucleotide position 274, at which a cytosine is substituted by a thymine leading to an amino acid change at protein position 67 from serine (TCC) to phenylalanine (TTC).

  16. B-52 control configured vehicles: Flight test results

    NASA Technical Reports Server (NTRS)

    Arnold, J. I.; Murphy, F. B.

    1976-01-01

    Recently completed B-52 Control Configured Vehicles (CCV) flight testing is summarized, and results are compared to analytical predictions. Results are presented for five CCV system concepts: ride control, maneuver load control, flutter mode control, augmented stability, and fatigue reduction. Test results confirm analytical predictions and show that CCV system concepts achieve performance goals when operated individually or collectively.

  17. X-15 drop launch, view from B-52 mothership

    NASA Technical Reports Server (NTRS)

    1960-01-01

    This roughly 20-second video clip shows the first planned glide flight of X-15 #1 on June 8, 1959. Then-North American pilot Scott Crossfield flew the mission, dropped from the B-52A mothership that bore the tail number 0003.

  18. 42 CFR 52b.12 - What are the minimum requirements of construction and equipment?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and equipment? 52b.12 Section 52b.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... requirements of construction and equipment? (a) General. In addition to being subject to other laws... have been determined by the Director to constitute minimum requirements of construction and equipment...

  19. 46 CFR 52.01-105 - Piping, valves and fittings (modifies PG-58 and PG-59).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Piping, valves and fittings (modifies PG-58 and PG-59). 52.01-105 Section 52.01-105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-105 Piping, valves and fittings (modifies PG-58 and PG-59). (a) Boiler external piping within...

  20. 46 CFR 52.01-95 - Design (modifies PG-16 through PG-31 and PG-100).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Design (modifies PG-16 through PG-31 and PG-100). 52.01-95 Section 52.01-95 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-95 Design (modifies PG-16 through PG-31 and PG-100). (a) Requirements. Boilers required to be designe...

  1. 46 CFR 52.01-105 - Piping, valves and fittings (modifies PG-58 and PG-59).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Piping, valves and fittings (modifies PG-58 and PG-59). 52.01-105 Section 52.01-105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-105 Piping, valves and fittings (modifies PG-58 and PG-59). (a) Boiler external piping within...

  2. 46 CFR 52.01-105 - Piping, valves and fittings (modifies PG-58 and PG-59).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Piping, valves and fittings (modifies PG-58 and PG-59). 52.01-105 Section 52.01-105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-105 Piping, valves and fittings (modifies PG-58 and PG-59). (a) Boiler external piping within...

  3. 46 CFR 52.01-95 - Design (modifies PG-16 through PG-31 and PG-100).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Design (modifies PG-16 through PG-31 and PG-100). 52.01-95 Section 52.01-95 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-95 Design (modifies PG-16 through PG-31 and PG-100). (a) Requirements. Boilers required to be designe...

  4. B-52/Pegasus with X-43A landing after first captive carry flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  5. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  6. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  7. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  8. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  9. 48 CFR 52.247-30 - F.o.b. Origin, Contractor's Facility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin, Contractor... Clauses 52.247-30 F.o.b. Origin, Contractor's Facility. As prescribed in 47.303-2(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. origin, contractor's facility: F.o...

  10. HiMAT Subscale Research Vehicle Mated to B-52 Mothership in Flight, Close-up View

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A close-up view of the Highly Maneuverable Aircraft Technology (HiMAT) research vehicle attached to a wing pylon on NASA's B-52 mothership during a 1980 test flight. The HiMAT used sharply swept-back wings and a canard configuration to test possible technology for advanced fighters. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported

  11. Preflight transient dynamic analyses of B-52 aircraft carrying Space Shuttle solid rocket booster drop-test vehicle

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1984-01-01

    This paper concerns the transient dynamic analysis of the B-52 aircraft carrying the Space Shuttle solid rocket booster drop test vehicle (SRB/DTV). The NASA structural analysis (NASTRAN) finite element computer program was used in the analysis. The B-52 operating conditions considered for analysis were (1) landing and (2) braking on aborted takeoff runs. The transient loads for the B-52 pylon front and rear hooks were calculated. The results can be used to establish the safe maneuver envelopes for the B-52 carrying the SRB/DTV in landings and brakings.

  12. Pre-flight transient dynamic analysis of B-52 carrying Space Shuttle solid rocket booster drop-test vehicle

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1983-01-01

    This paper concerns the transient dynamic analysis of the B-52 aircraft carrying the Space Shuttle solid-rocket booster drop-test vehicle (SRB/DTV). The NASA structural analysis (NASTRAN) finite-element computer program was used in the analysis. The B-52 operating conditions considered for analysis were (1) landing and (2) braking on aborted takeoff runs. The transient loads for the B-52 pylon front and rear hooks were calculated. The results can be used to establish the safe maneuver envelopes for the B-52 carrying the SRB/DTV in landings and brakings.

  13. B-52/Pegasus with X-43A in flight over Pacific Ocean

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  14. Close view of B-52/Pegasus with X-43A in flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  15. B-52/Pegasus with X-43A departing on first captive flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  16. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  17. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  18. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  19. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  20. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  1. 52. LOOKING NORTHWEST FROM BETWEEN TRUSSES B AND C OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. LOOKING NORTHWEST FROM BETWEEN TRUSSES B AND C OF THEATER ATTIC. NOTE CURVE OF ELLIPTICAL CEILING BELOW, AIR SUPPLY DUCTS, AND LATERAL BRACING ADDED BETWEEN TRUSSES. - Auditorium Building, 430 South Michigan Avenue, Chicago, Cook County, IL

  2. 33 CFR 117.753 - Ship Channel, Great Egg Harbor Bay.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Ship Channel, Great Egg Harbor Bay. 117.753 Section 117.753 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND..., Great Egg Harbor Bay. The draw of the S52 (Ship Channel) bridge, mile 0.5 between Somers Point and Ocean...

  3. 33 CFR 117.753 - Ship Channel, Great Egg Harbor Bay.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Ship Channel, Great Egg Harbor Bay. 117.753 Section 117.753 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND..., Great Egg Harbor Bay. The draw of the S52 (Ship Channel) bridge, mile 0.5 between Somers Point and Ocean...

  4. 7 CFR 52.38b - Statistical sampling procedures for on-line inspection by attributes of processed fruits and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Statistical sampling procedures for on-line inspection by attributes of processed fruits and vegetables. 52.38b Section 52.38b Agriculture Regulations of... Regulations Governing Inspection and Certification Sampling § 52.38b Statistical sampling procedures for on...

  5. 7 CFR 52.38b - Statistical sampling procedures for on-line inspection by attributes of processed fruits and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Statistical sampling procedures for on-line inspection by attributes of processed fruits and vegetables. 52.38b Section 52.38b Agriculture Regulations of... Regulations Governing Inspection and Certification Sampling § 52.38b Statistical sampling procedures for on...

  6. Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms.

    PubMed

    Winchester, Robert; Pitt, Jane; Charurat, Manhattan; Magder, Laurence S; Göring, Harald H H; Landay, Alan; Read, Jennifer S; Shearer, William; Handelsman, Edward; Luzuriaga, Katherine; Hillyer, George V; Blattner, William

    2004-06-01

    The transmission of HIV-1 from mother to child during pregnancy is unlike other types of HIV-1 transmission because the child shares major histocompatibility complex (MHC) genes with the mother during a time while the mother is induced to tolerate the paternally derived fetal MHC molecules, in part through natural killer (NK) recognition of MHC polymorphisms. The relevance of these immune mechanisms to HIV-1 transmission was assessed by determining the HLA-B alleles of mother and infant. Almost half (48%) of mothers who transmitted with low viral loads had HLA-B*1302, B*3501, B*3503, B*4402, or B*5001 alleles, compared with 8% of nontransmitting mothers (P=0.001). Conversely, 25% of mothers who did not transmit despite high viral loads had B*4901 and B*5301, vs. 5% of transmitting mothers (P=0.003), a pattern of allelic involvement distinct from that influencing HIV-1 infection outcome. The infant's HLA-B alleles did not appear associated with transmission risk. The HLA-B*4901 and B*5301 alleles that were protective in the mother both differed respectively from the otherwise identical susceptibility alleles, B*5001 and B*3501, by 5 amino acids encoding the ligand for the KIR3DL1 NK receptor. These results suggest that the probable molecular basis of the observed association involves definition of the maternal NK recognition repertoire by engagement of NK receptors with polymorphic ligands encoded by maternal HLA-B alleles, and that the placenta is the likely site of the effect that appears to protect against transmission of maternal HIV-1 through interrelating adaptive and innate immune recognition.

  7. Stress analyses of B-52 pylon hooks

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1985-01-01

    The NASTRAN finite element computer program was used in the two dimensional stress analysis of B-52 carrier aircraft pylon hooks: (1) old rear hook (which failed), (2) new rear hook (improved geometry), (3) new DAST rear hook (derated geometry), and (4) front hook. NASTRAN model meshes were generated by the aid of PATRAN-G computer program. Brittle limit loads for all the four hooks were established. The critical stress level calculated from NASTRAN agrees reasonably well with the values predicted from the fracture mechanics for the failed old rear hook.

  8. Hepatitis B virus surface antigen (HBsAg)-positive and HBsAg-negative hepatitis B virus infection among mother-teenager pairs 13 years after neonatal hepatitis B virus vaccination.

    PubMed

    Yao, Qing-Qing; Dong, Xiao-Lian; Wang, Xue-Cai; Ge, Sheng-Xiang; Hu, An-Qun; Liu, Hai-Yan; Wang, Yueping Alex; Yuan, Quan; Zheng, Ying-Jie

    2013-02-01

    It is unclear whether a mother who is negative for hepatitis B virus surface antigen (HBsAg) but positive for hepatitis B virus (HBV) is at potential risk for mother-to-child transmission of HBV. This study, using a paired mother-teenager population, aimed to assess whether maternal HBsAg-negative HBV infection ((hn)HBI) is a significant source of child HBV infection (HBI). A follow-up study with blood collection has been conducted on the 93 mother-teenager pairs from the initial 135 pregnant woman-newborn pairs 13 years after neonatal HBV vaccination. Serological and viral markers of HBV have been tested, and phylogenetic analysis of HBV isolates has been done. The HBI prevalence was 1.9% (1 (hn)HBI/53) for teenage children of non-HBI mothers, compared with 16.7% (1 (hn)HBI/6) for those of (hn)HBI mothers and 2.9% (1 HBsAg-positive HBV infection [(hp)HBI]/34) for those of (hp)HBI mothers. Similar viral sequences have been found in one pair of whom both the mother and teenager have had (hn)HBI. In comparison with the (hp)HBI cases, those with (hn)HBI had a lower level of HBV load and a higher proportion of genotype-C strains, which were accompanied by differentiated mutations (Q129R, K141E, and Y161N) of the "a" determinant of the HBV surface gene. Our findings suggest that mother-to-teenager transmission of (hn)HBI can occur among those in the neonatal HBV vaccination program.

  9. Hepatitis B Virus Surface Antigen (HBsAg)-Positive and HBsAg-Negative Hepatitis B Virus Infection among Mother-Teenager Pairs 13 Years after Neonatal Hepatitis B Virus Vaccination

    PubMed Central

    Yao, Qing-Qing; Dong, Xiao-Lian; Wang, Xue-Cai; Ge, Sheng-Xiang; Hu, An-Qun; Liu, Hai-Yan; Wang, Yueping Alex

    2013-01-01

    It is unclear whether a mother who is negative for hepatitis B virus surface antigen (HBsAg) but positive for hepatitis B virus (HBV) is at potential risk for mother-to-child transmission of HBV. This study, using a paired mother-teenager population, aimed to assess whether maternal HBsAg-negative HBV infection (hnHBI) is a significant source of child HBV infection (HBI). A follow-up study with blood collection has been conducted on the 93 mother-teenager pairs from the initial 135 pregnant woman-newborn pairs 13 years after neonatal HBV vaccination. Serological and viral markers of HBV have been tested, and phylogenetic analysis of HBV isolates has been done. The HBI prevalence was 1.9% (1 hnHBI/53) for teenage children of non-HBI mothers, compared with 16.7% (1 hnHBI/6) for those of hnHBI mothers and 2.9% (1 HBsAg-positive HBV infection [hpHBI]/34) for those of hpHBI mothers. Similar viral sequences have been found in one pair of whom both the mother and teenager have had hnHBI. In comparison with the hpHBI cases, those with hnHBI had a lower level of HBV load and a higher proportion of genotype-C strains, which were accompanied by differentiated mutations (Q129R, K141E, and Y161N) of the “a” determinant of the HBV surface gene. Our findings suggest that mother-to-teenager transmission of hnHBI can occur among those in the neonatal HBV vaccination program. PMID:23254298

  10. 46 CFR 52.01-110 - Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges (modifies PG-60). 52.01-110 Section 52.01-110 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-110 Water-level indicators, water...

  11. 46 CFR 52.01-110 - Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges (modifies PG-60). 52.01-110 Section 52.01-110 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-110 Water-level indicators, water...

  12. 46 CFR 52.01-110 - Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges (modifies PG-60). 52.01-110 Section 52.01-110 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-110 Water-level indicators, water...

  13. 46 CFR 52.01-110 - Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges (modifies PG-60). 52.01-110 Section 52.01-110 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-110 Water-level indicators, water...

  14. 46 CFR 52.01-110 - Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Water-level indicators, water columns, gauge-glass connections, gauge cocks, and pressure gauges (modifies PG-60). 52.01-110 Section 52.01-110 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-110 Water-level indicators, water...

  15. Research Pilot Milt Thompson in M2-F2 Aircraft Attached to B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1966-01-01

    NASA research pilot Milt Thompson sits in the M2-F2 'heavyweight' lifting body research vehicle before a 1966 test flight. The M2-F2 and the other lifting-body designs were all attached to a wing pylon on NASA's B-52 mothership and carried aloft. The vehicles were then drop-launched and, at the end of their flights, glided back to wheeled landings on the dry lake or runway at Edwards AFB. The lifting body designs influenced the design of the Space Shuttle and were also reincarnated in the design of the X-38 in the 1990s. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft

  16. Relationship between container ship underwater noise levels and ship design, operational and oceanographic conditions

    PubMed Central

    McKenna, Megan F.; Wiggins, Sean M.; Hildebrand, John A.

    2013-01-01

    Low-frequency ocean ambient noise is dominated by noise from commercial ships, yet understanding how individual ships contribute deserves further investigation. This study develops and evaluates statistical models of container ship noise in relation to design characteristics, operational conditions, and oceanographic settings. Five-hundred ship passages and nineteen covariates were used to build generalized additive models. Opportunistic acoustic measurements of ships transiting offshore California were collected using seafloor acoustic recorders. A 5–10 dB range in broadband source level was found for ships depending on the transit conditions. For a ship recorded multiple times traveling at different speeds, cumulative noise was lowest at 8 knots, 65% reduction in operational speed. Models with highest predictive power, in order of selection, included ship speed, size, and time of year. Uncertainty in source depth and propagation affected model fit. These results provide insight on the conditions that produce higher levels of underwater noise from container ships.

  17. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Adoption of section I of the ASME Boiler and Pressure Vessel Code. 52.01-2 Section 52.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power...

  18. 46 CFR 52.01-120 - Safety valves and safety relief valves (modifies PG-67 through PG-73).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Safety valves and safety relief valves (modifies PG-67 through PG-73). 52.01-120 Section 52.01-120 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-120 Safety valves and safety relief valves (modifies PG-67 through PG-73). (a)...

  19. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section I of the ASME Boiler and Pressure Vessel Code. 52.01-2 Section 52.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power...

  20. 46 CFR 52.01-120 - Safety valves and safety relief valves (modifies PG-67 through PG-73).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Safety valves and safety relief valves (modifies PG-67 through PG-73). 52.01-120 Section 52.01-120 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-120 Safety valves and safety relief valves (modifies PG-67 through PG-73). (a)...

  1. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Adoption of section I of the ASME Boiler and Pressure Vessel Code. 52.01-2 Section 52.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power...

  2. 46 CFR 52.01-120 - Safety valves and safety relief valves (modifies PG-67 through PG-73).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Safety valves and safety relief valves (modifies PG-67 through PG-73). 52.01-120 Section 52.01-120 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-120 Safety valves and safety relief valves (modifies PG-67 through PG-73). (a)...

  3. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Adoption of section I of the ASME Boiler and Pressure Vessel Code. 52.01-2 Section 52.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power...

  4. 46 CFR 52.01-120 - Safety valves and safety relief valves (modifies PG-67 through PG-73).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Safety valves and safety relief valves (modifies PG-67 through PG-73). 52.01-120 Section 52.01-120 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-120 Safety valves and safety relief valves (modifies PG-67 through PG-73). (a)...

  5. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Adoption of section I of the ASME Boiler and Pressure Vessel Code. 52.01-2 Section 52.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power...

  6. 46 CFR 52.01-120 - Safety valves and safety relief valves (modifies PG-67 through PG-73).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Safety valves and safety relief valves (modifies PG-67 through PG-73). 52.01-120 Section 52.01-120 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-120 Safety valves and safety relief valves (modifies PG-67 through PG-73). (a)...

  7. 48 CFR 52.247-35 - F.o.b. Destination, Within Consignee's Premises.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination, Within... Clauses 52.247-35 F.o.b. Destination, Within Consignee's Premises. As prescribed in 47.303-7(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. destination...

  8. [Comparative analysis of four kinds of vitamin B of milk of lactating mothers and maternal and infant nutritional status in Chinese urban and rural areas].

    PubMed

    Liu, Huihui; Han, Xiuxia; Liu, Liegang; Jiang, Dianchen; Yi, Mingji; Zheng, Yanfeng; Ma, Aiguo

    2014-05-01

    To understand the nutritional level of lactating mothers and infant by detecting the content of the vitamin B1, vitamin B2, vitamin B6, nicotinic of milk of urban and rural areas and to provide the basis for improving vitamin nutritional status of lactating women and their babies. Totally 92 pairs of breastfeeding healthy mothers and their children in Shandong Province were selected. 34 pairs were in a urban area and 58 pairs were in a rural area. Collect the milk of selected lactating mothers and the urine of the lactating mothers and their children. Detect the content of vitamin B1, vitamin B2, vitamin B6, nicotinic of milk of lactating mothers and the content of vitamin B1, vitamin B2, nicotinic of urine of lactating mothers and their children. The content of vitamin B2, vitamin B6 and niacin of milk of urban lactating mothers were significantly higher than that of rural lactating mothers. The results of detection showed the vitamin B2 of milk of urban lactating mothers was 149.77 microg/100 g, which was significantly higher than that of rural women in 85.09 microg/100 g (P < 0.05). Vitamin B6 and niacin contents were 15.29 microg/100 g, 40.83 microg/100 g, which were also higher than that in rural lactating milk (6.69 microg/100 g and 24.48 microg/100 g) (All values P < 0.05). However, vitamin B1 of milk of urban and rural lactating mothers were 5.54 microg/100 g and 4.80 microg/100 g respectively, which had no significant difference. Urine analysis showed vitamin B2 and niacin of urban mothers and children were significantly higher than that in rural area (P < 0.05). But the level of vitamin B1 of rural children was higher than that of urban children (P < 0.05). There was no significant difference in the vitamin B1 between urban and rural mothers. The insufficient percentages of vitamin B1, vitamin B2. niacin in urban mothers was 23.5%, 32.3% and 17.6%, and that in rural mothers were 29.3%, 82.8% and 53.4%. The deficiency percentage of vitamin B1, vitamin B2

  9. 48 CFR 52.247-48 - F.o.b. Destination-Evidence of Shipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination... Provisions and Clauses 52.247-48 F.o.b. Destination—Evidence of Shipment. As prescribed in 47.305-4(c), insert the following clause: F.o.b. Destination—Evidence of Shipment (FEB 1999) (a) If this contract is...

  10. B-52/Pegasus with X-43A landing after first captive carry flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  11. Operation Redwing -- Project 5. 2. In-flight participation of a B-52. Report for May-July 1956

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, F.L.

    1985-04-01

    The primary objective of this Project was to obtain measured-energy input and aircraft-response data on an instrumented B-52 aircraft when subjected to the thermal, blast, and gust effects of a nuclear explosion. To accomplish this, analysis was used in selecting the spatial location for the B-52, relative to a detonation, that would result in the desired aircraft inputs and responses. The B-52 was extensively instrumented with the major portion of the instrumentation devoted to measuring aircraft responses. The B-52 participated in nine shots, including one shot which the aircraft aborted just prior to time zero because of Bombing Navigation Systemmore » difficulties. The reliability of the instrumentation system was between 95% and 100% throughout the test program.« less

  12. Hepatitis B Immunoprophylactic Failure and Characteristics of the Hepatitis B Virus Gene in Mother-Infant Pairs in Parts of China.

    PubMed

    Yin, Wen Jiao; Shen, Li Ping; Wang, Fu Zhen; Zhang, Guo Min; Zheng, Hui; Wang, Feng; Liu, Tie Zhu; Meng, Qing Ling; Yi, Yao; Cui, Fu Qiang; Bi, Sheng Li

    2016-11-01

    To determine the hepatitis B immunoprophylactic failure rate in infants born to hepatitis B virus (HBV) infected mothers and to characterize HBV genes. HBV-serological testing was conducted for pregnant women and infants. The complete genomes of 30 HBV isolates were sequenced, and genetic characteristics were analyzed using MEGA 5 software. The immunoprophylactic failure rate for infants who had completed the scheduled hepatitis B vaccination program was 5.76% (32/556). High sequence homology (99.8%-100%) was observed in 8 of the 10 mother-infant pairs. We identified 19 subgenotype C2 strains, 9 subgenotype B2 strains, and 2 subgenotype C1 strains. Three serotypes were detected: adr (19/30), adw (9/30), and ayw (2/30). The frequency of amino acid mutation of the 'a' determinant region was 16.67% (5/30), including that of Q129H, F134Y, S136Y, and G145E. We detected 67 amino acid mutations in the basal core promoter, precore, and core regions of the genome. The immunoprophylactic failure rate in infants born to HBV-infected mothers is low in the regions of China examined during this study. Moreover, HBV mutation in the 'a' determinant region could not account for immunoprophylactic failure for all infants. Copyright © 2016 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

  13. 40 CFR 52.122 - Negative declarations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

  14. 40 CFR 52.122 - Negative declarations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

  15. 40 CFR 52.122 - Negative declarations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

  16. 40 CFR 52.122 - Negative declarations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

  17. 40 CFR 52.122 - Negative declarations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

  18. Female adoptees' experiences balancing relationships with biological and adoptive mothers post-reunification.

    PubMed

    Richardson, Angelle; Davey, Maureen P; Swint, Phyllis A

    2013-07-01

    Using a feminist postmodern perspective and the sensitizing concept of split loyalties from Contextual Theory, the primary purpose of this qualitative study was to develop a better understanding of how adult female adoptees from closed adoptions negotiate relationships with their adoptive and biological mothers post-reunion. We conducted semi-structured individual interviews with nine adult female adoptees, ages 28-52, who were adopted prior to the age of two. Six were Caucasian, three were African American, and the average age at reunion was 29. Grounded theory techniques were used to code the qualitative data, in particular the constant comparative method of analysis. Four main categories emerged: (a) Negotiating Mother-Daughter Relationships, (b) Relating to Mothers Equitably, (c) Loyalty, and (d) Adoptees' Emotional Needs. Our findings suggest the adoptive mother-daughter relationship has a salient effect on adoptees' relationships with biological mothers post-reunion. Loyalty to the adoptive mother seems to influence the evolving relationship and closeness displayed toward the birth mother. Adult female adoptees from closed adoptions described struggling with managing their two mother-daughter relationships and need clinical help addressing their own emotional needs. © 2012 American Association for Marriage and Family Therapy.

  19. A B-52H, tail number 61-0025, arrives at NASA's Dryden Flight Research Center after landing July 30,

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA Dryden Flight Research Center, Edwards, California, received an 'H' model B-52 Stratofortress aircraft on July 30, 2001. The B-52H will be used as an air-launch aircraft supporting NASA's flight research and advanced technology demonstration efforts. Dryden received the B-52H from the U.S. Air Force's (USAF) 23rd Bomb Squadron, 5th Bombardment Wing (Air Combat Command), located at Minot AFB, N.D. A USAF crew flew the aircraft to Dryden. The aircraft, USAF tail number 61-0025, will be loaned initially, then later transferred from the USAF to NASA. The B-52H is scheduled to leave Dryden Aug. 2 for de-militarization and Programmed Depot Maintenance (PDM) at Tinker Air Force Base (AFB), Oklahoma. The depot-level maintenance is scheduled to last about six months and includes a thorough maintenance and inspection process. The newly arrived B-52H is slated to replace Dryden's famous B-52B '008,' in the 2003-2004 timeframe. It will take about one year for the B-52H to be ready for flight research duties. This time includes PDM, construction of the new pylon, installation of the flight research instrumentation equipment, and aircraft envelope clearance flights.

  20. Docking Mechanism on Progress 52

    NASA Image and Video Library

    2014-02-03

    ISS038-E-041175 (3 Feb. 2014) --- This close-up view shows the docking mechanism of the unpiloted Russian ISS Progress 52 resupply ship as it undocks from the International Space Station's Pirs Docking Compartment at 11:21 a.m. (EST) on Feb. 3, 2014. The Progress backed away to a safe distance from the orbital complex to begin several days of tests to study thermal effects of space on its attitude control system. Filled with trash and other unneeded items, the Russian resupply ship will be commanded to re-enter Earth's atmosphere Feb. 11 and disintegrate harmlessly over the Pacific Ocean.

  1. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Andy Blua and Jeff Doughty of Dryden's Experimental Fabrication Shop, along with B-52 Crew Chief Dan Bains and assistant Mark Thompson, all eye the new X-38 pylon during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California. The fit-check was the first time the 1,200-pound steel pylon, which was fabricated at Dryden, was mated to the B-52. The pylon served as an 'adapter' that allowed the X-38 to be attached to the B-52's wing. Earlier flight research vehicles had used the X-15 pylon for attachment to and launch from the B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the Hi

  2. Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.

    PubMed

    Chikata, Takayuki; Murakoshi, Hayato; Koyanagi, Madoka; Honda, Kazutaka; Gatanaga, Hiroyuki; Oka, Shinichi; Takiguchi, Masafumi

    2017-12-12

    HLA-B*52:01-C*12:02, which is found in approximately 20% of all Japanese persons, is well known to be associated with ulcerative colitis and Takayasu arteritis. This haplotype is also known to be protective in individuals infected with human immunodeficiency virus (HIV) type 1. Recent studies showed that HLA-B*52:01-restricted HIV-1-specific T cells suppress HIV-1 and that HLA-C*12:02 together with KIR2DL2 play an important role in natural killer cell-mediated control of HIV-1. However, the role of HLA-C*12:02-restricted cytotoxic T lymphocytes (CTLs) in suppressing HIV-1 replication remains unknown. In the present study, we demonstrated that HLA-C*12:02-restricted CTLs specific for 2 immunodominant epitopes, Pol IY11 and Nef MY9, contributed to the suppression of HIV-1 replication in HIV-1-infected individuals. Further analysis demonstrated that these 2 HLA-C*12:02-restricted CTLs together with 4 HLA-B*52:01-restricted ones effectively suppressed HIV-1 in individuals with the HLA-B*52:01-C*12:02 haplotype. Thus, both HLA-C*12:02 and HLA-B*52:01 alleles contribute to HIV-1 suppression via both HIV-1-specific CTLs and natural killer cells in individuals with this haplotype. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

  3. 48 CFR 47.305-16 - Shipping characteristics.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Shipping characteristics... CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.305-16 Shipping characteristics... shipments of agreed size. (b) Guaranteed shipping characteristics. (1) The contracting officer shall insert...

  4. 57. Interior of launch control center, crew in B52 seats, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Interior of launch control center, crew in B-52 seats, looking east - Ellsworth Air Force Base, Delta Flight, Launch Control Facility, County Road CS23A, North of Exit 127, Interior, Jackson County, SD

  5. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells.

    PubMed

    Gorgani-Firuzjaee, Sattar; Khatami, Shohreh; Adeli, Khosrow; Meshkani, Reza

    2015-09-04

    Hepatic de-novo lipogenesis and production of triglyceride rich VLDL are regulated via the phosphoinositide 3-kinase cascade, however, the role of a negative regulator of this pathway, the SH2 domain-containing inositol 5-phosphatase (SHIP2) in this process, remains unknown. In the present study, we investigated the molecular link between SHIP2 expression and metabolic dyslipidemia using overexpression or suppression of SHIP2 gene in HepG2 cells. The results showed that overexpression of the wild type SHIP2 gene (SHIP2-WT) led to a higher total lipid content (28%) compared to control, whereas overexpression of the dominant negative SHIP2 gene (SHIP2-DN) reduced total lipid content in oleate treated cells by 40%. Overexpression of SHIP2-WT also led to a significant increase in both secretion of apoB100 containing lipoproteins and de-novo lipogenesis, as demonstrated by an enhancement in secreted apoB100 and MTP expression, increased intra and extracellular triglyceride levels and enhanced expression of lipogenic genes such as SREBP1c, FAS and ACC. On the other hand, overexpression of the SHIP2-DN gene prevented oleate-induced de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells. Collectively, these findings suggest that SHIP2 expression level is a key determinant of hepatic lipogenesis and lipoprotein secretion, and its inhibition could be considered as a potential target for treatment of dyslipidemia. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. NASA's Brad Neal, X-43A Monitor Station Operator aboard NASA's B-52B mothership, performing pre-flight checks on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    NASA X-43A Monitor Station Operator Brad Neal performs final checks and pre-flight preparations aboard the B-52 for the third X-43A research vehicle Mach 10 flight on November 16, 2004. Takeoff of the B-52B mothership carrying the X-43A took place at 1 p.m., PST, with launch of the booster rocket/X-43A approximately an hour later.

  7. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) To, and placed on, the carrier's wharf (at shipside, within reach of the ship's loading tackle, when the shipping point is within a port area having water transportation service) or the carrier's freight... terms of the governing freight classification or tariff (or Government rate tender) under which lowest...

  8. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) To, and placed on, the carrier's wharf (at shipside, within reach of the ship's loading tackle, when the shipping point is within a port area having water transportation service) or the carrier's freight... terms of the governing freight classification or tariff (or Government rate tender) under which lowest...

  9. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) To, and placed on, the carrier's wharf (at shipside, within reach of the ship's loading tackle, when the shipping point is within a port area having water transportation service) or the carrier's freight... terms of the governing freight classification or tariff (or Government rate tender) under which lowest...

  10. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) To, and placed on, the carrier's wharf (at shipside, within reach of the ship's loading tackle, when the shipping point is within a port area having water transportation service) or the carrier's freight... terms of the governing freight classification or tariff (or Government rate tender) under which lowest...

  11. 46 CFR 52.01-100 - Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55). 52.01-100 Section 52.01-100 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-100 Openings and compensation (modifies PG-32 through PG-39, PG-42...

  12. 46 CFR 52.01-100 - Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55). 52.01-100 Section 52.01-100 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-100 Openings and compensation (modifies PG-32 through PG-39, PG-42...

  13. 46 CFR 52.01-100 - Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55). 52.01-100 Section 52.01-100 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-100 Openings and compensation (modifies PG-32 through PG-39, PG-42...

  14. 46 CFR 52.01-100 - Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55). 52.01-100 Section 52.01-100 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-100 Openings and compensation (modifies PG-32 through PG-39, PG-42...

  15. 46 CFR 52.01-100 - Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Openings and compensation (modifies PG-32 through PG-39, PG-42 through PG-55). 52.01-100 Section 52.01-100 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-100 Openings and compensation (modifies PG-32 through PG-39, PG-42...

  16. Cost-effectiveness analysis of Option B+ for HIV prevention and treatment of mothers and children in Malawi.

    PubMed

    Fasawe, Olufunke; Avila, Carlos; Shaffer, Nathan; Schouten, Erik; Chimbwandira, Frank; Hoos, David; Nakakeeto, Olive; De Lay, Paul

    2013-01-01

    The Ministry of Health in Malawi is implementing a pragmatic and innovative approach for the management of all HIV-infected pregnant women, termed Option B+, which consists of providing life-long antiretroviral treatment, regardless of their CD4 count or clinical stage. Our objective was to determine if Option B+ represents a cost-effective option. A decision model simulates the disease progression of a cohort of HIV-infected pregnant women receiving prophylaxis and antiretroviral therapy, and estimates the number of paediatric infections averted and maternal life years gained over a ten-year time horizon. We assess the cost-effectiveness from the Ministry of Health perspective while taking into account the practical realities of implementing ART services in Malawi. If implemented as recommended by the World Health Organization, options A, B and B+ are equivalent in preventing new infant infections, yielding cost effectiveness ratios between US$ 37 and US$ 69 per disability adjusted life year averted in children. However, when the three options are compared to the current practice, the provision of antiretroviral therapy to all mothers (Option B+) not only prevents infant infections, but also improves the ten-year survival in mothers more than four-fold. This translates into saving more than 250,000 maternal life years, as compared to mothers receiving only Option A or B, with savings of 153,000 and 172,000 life years respectively. Option B+ also yields favourable incremental cost effectiveness ratios (ICER) of US$ 455 per life year gained over the current practice. In Malawi, Option B+ represents a favorable policy option from a cost-effectiveness perspective to prevent future infant infections, save mothers' lives and reduce orphanhood. Although Option B+ would require more financial resources initially, it would save societal resources in the long-term and represents a strategic option to simplify and integrate HIV services into maternal, newborn and child

  17. NF-κB Transcriptional Activity Is Modulated by FK506-binding Proteins FKBP51 and FKBP52

    PubMed Central

    Erlejman, Alejandra G.; De Leo, Sonia A.; Mazaira, Gisela I.; Molinari, Alejandro M.; Camisay, María Fernanda; Fontana, Vanina; Cox, Marc B.; Piwien-Pilipuk, Graciela; Galigniana, Mario D.

    2014-01-01

    Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to expand this model to other nuclear factors that are also subject to nuclear-cytoplasmic shuttling, we analyzed whether these immunophilins modulate NF-κB signaling. It is demonstrated that FKBP51 impairs both the nuclear translocation rate of NF-κB and its transcriptional activity. The inhibitory action of FKBP51 requires neither the peptidylprolyl-isomerase activity of the immunophilin nor its association with Hsp90. The TPR domain of FKBP51 is essential. On the other hand, FKBP52 favors the nuclear retention time of RelA, its association to a DNA consensus binding sequence, and NF-κB transcriptional activity, the latter effect being strongly dependent on the peptidylprolyl-isomerase activity and also on the TPR domain of FKBP52, but its interaction with Hsp90 is not required. In unstimulated cells, FKBP51 forms endogenous complexes with cytoplasmic RelA. Upon cell stimulation with phorbol ester, the NF-κB soluble complex exchanges FKBP51 for FKBP52, and the NF-κB biological effect is triggered. Importantly, FKBP52 is functionally recruited to the promoter region of NF-κB target genes, whereas FKBP51 is released. Competition assays demonstrated that both immunophilins antagonize one another, and binding assays with purified proteins suggest that the association of RelA and immunophilins could be direct. These observations suggest that the biological action of NF-κB in different cell types could be positively regulated by a high FKBP52/FKBP51 expression ratio by favoring NF-κB nuclear retention, recruitment to the promoter regions of target genes, and transcriptional activity. PMID:25104352

  18. Commercial winged booster to launch satellites from B-52

    NASA Astrophysics Data System (ADS)

    Covault, Craig

    1988-06-01

    A newly developed commercial winged space booster, the Pegasus, which will launch satellites from a B-52, is described. The booster will be able to launch a 600 lb, 72 in long craft into a 250 nm equatorial orbit. The Pegasus is 49.2 ft long with a 22 ft wing span and a weight of 40,000 lb. The winged design allows for an angle of attack of 20 degrees and a supersonic lift over drag ratio of 4:1. It operates with three solid rocket motors and will be launched from a B-52 at an altitude of 40,000 ft. The first motor provides an average of 112,000 lbs of thrust for about 82 seconds; burnout occurs at 208,000 ft and Mach 8.7. The third stage provides 9,000 lbs of thrust for 65 seconds, accelerating the vehicle into 25,000 fps orbital velocity. The first launch will be a 400 lb relay satellite targeted for July 1989 over the Pacific Ocean. Future launches will be possible from any site and will cost 10 million dollars. The Pegasus can also carry a 1500 payload at high altitude Mach cruise flights that do not achieve orbit, providing data to validate spaceplane conceptual fluid dynamic codes generated by computer.

  19. 48 CFR 52.247-38 - F.o.b. Inland Carrier, Point of Exportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Inland Carrier... Provisions and Clauses 52.247-38 F.o.b. Inland Carrier, Point of Exportation. As prescribed in 47.303-10(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. inland...

  20. 48 CFR 52.247-61 - F.o.b. Origin-Minimum Size of Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin-Minimum Size... Clauses 52.247-61 F.o.b. Origin—Minimum Size of Shipments. As prescribed in 47.305-16(c), insert the following clause in solicitations and contracts when volume rates may apply: F.o.b. Origin—Minimum Size of...

  1. 48 CFR 52.247-59 - F.o.b. Origin-Carload and Truckload Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin-Carload and... Clauses 52.247-59 F.o.b. Origin—Carload and Truckload Shipments. As prescribed in 47.305-16(a), insert the following clause in solicitations and contracts when it is contemplated that they may result in f.o.b...

  2. 48 CFR 52.247-39 - F.o.b. Inland Point, Country of Importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Inland Point... Provisions and Clauses 52.247-39 F.o.b. Inland Point, Country of Importation. As prescribed in 47.303-11(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. inland point...

  3. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Tom McMullen, Chief of Dryden's Experimental Fabrication Shop, makes adjustments to the new pylon for NASA's X-38 during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California, in 1997. The fit-check was the first time the 1,200-pound steel pylon was mated to the B-52 following fabrication at Dryden by the Center's Experimental Fabrication Shop. The pylon was built as an 'adapter' to allow the X-38 to be attached to and launched from the B-52's wing. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST

  4. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The new pylon for the X-38 following a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California, in 1997. The fit-check was the first time the 1,200-pound steel pylon was mated to the B-52 following fabrication at Dryden by the Center's Experimental Fabrication Shop. The pylon was built as an 'adapter' to allow the X-38 research vehicle to be carried aloft and launched from the B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the

  5. Gamma Radiation from PSR B1055-52

    NASA Technical Reports Server (NTRS)

    Thompson, D. J.; Bailes, M.; Bertsch, D. L.; Cordes, J.; DAmico, N. D.; Esposito, J. A.; Finley, J.; Hartman, R. C.; Hermsen, W.; Kanbach, G.; hide

    1998-01-01

    The telescopes on the Compton Gamma Ray Observatory (CCRO) have observed PSR B1055-52 a number of times between 1991 and 1998. From these data, a more detailed picture of the gamma radiation from this source has been developed, showing several characteristics which distinguish this pulsar: the light curve is complex; there is no detectable unpulsed emission; the energy spectrum is flat, with no evidence of a sharp high-energy cutoff up to greater than 4 GeV. Comparisons of the gamma-ray data with observations at longer wavelengths show that no two of the known gamma-ray pulsars have quite the same characteristics; this diversity makes interpretation in terms of theoretical models difficult.

  6. Gamma Radiation from PSR B1055-52

    NASA Technical Reports Server (NTRS)

    Thompson, D. J.; Bailes, M.; Bertsch, D. L.; Cordes, J.; DAmico, N.; Esposito, J. A.; Finley, J.; Hartman, R. C.; Hermsen, W.; Kanbach, G.; hide

    1999-01-01

    The telescopes on the Compton Gamma Ray Observatory (CGRO) have observed PSR B1055-52 a number of times between 1991 and 1998. From these data, a more detailed picture of the gamma radiation from this source has been developed, showing several characteristics which distinguish this pulsar: the light curve is complex; there is no detectable unpulsed emission; the energy spectrum is flat, with no evidence of a sharp high-energy cutoff up to greater than 4 GeV. Comparisons of the gamma-ray data with observations at longer wavelengths show that no two of the known gamma-ray pulsars have quite the same characteristics; this diversity makes interpretation in terms of theoretical models difficult.

  7. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... such information is broadcast for the area in which the ship is navigating. (c) Every ship while at sea... at sea, all ships must maintain a continuous watch: (1) On VHF DSC channel 70, if the ship is fitted... earth station in accordance with § 80.1091(a)(1). (b) While at sea, all ships must maintain radio...

  8. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... such information is broadcast for the area in which the ship is navigating. (c) Every ship while at sea... at sea, all ships must maintain a continuous watch: (1) On VHF DSC channel 70, if the ship is fitted... earth station in accordance with § 80.1091(a)(1). (b) While at sea, all ships must maintain radio...

  9. 47 CFR 80.1123 - Watch requirements for ship stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... such information is broadcast for the area in which the ship is navigating. (c) Every ship while at sea... at sea, all ships must maintain a continuous watch: (1) On VHF DSC channel 70, if the ship is fitted... earth station in accordance with § 80.1091(a)(1). (b) While at sea, all ships must maintain radio...

  10. 48 CFR 52.247-58 - Loading, Blocking, and Bracing of Freight Car Shipments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Bracing of Freight Car Shipments. 52.247-58 Section 52.247-58 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-58 Loading, Blocking, and Bracing of Freight Car Shipments. As... be shipped in carload lots by rail: Loading, Blocking, and Bracing of Freight Car Shipments (APR 1984...

  11. 48 CFR 52.247-58 - Loading, Blocking, and Bracing of Freight Car Shipments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Bracing of Freight Car Shipments. 52.247-58 Section 52.247-58 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-58 Loading, Blocking, and Bracing of Freight Car Shipments. As... be shipped in carload lots by rail: Loading, Blocking, and Bracing of Freight Car Shipments (APR 1984...

  12. 48 CFR 52.247-58 - Loading, Blocking, and Bracing of Freight Car Shipments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Bracing of Freight Car Shipments. 52.247-58 Section 52.247-58 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-58 Loading, Blocking, and Bracing of Freight Car Shipments. As... be shipped in carload lots by rail: Loading, Blocking, and Bracing of Freight Car Shipments (APR 1984...

  13. 48 CFR 52.247-58 - Loading, Blocking, and Bracing of Freight Car Shipments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Bracing of Freight Car Shipments. 52.247-58 Section 52.247-58 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-58 Loading, Blocking, and Bracing of Freight Car Shipments. As... be shipped in carload lots by rail: Loading, Blocking, and Bracing of Freight Car Shipments (APR 1984...

  14. 48 CFR 52.247-58 - Loading, Blocking, and Bracing of Freight Car Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... be shipped in carload lots by rail: Loading, Blocking, and Bracing of Freight Car Shipments (APR 1984... Bracing of Freight Car Shipments. 52.247-58 Section 52.247-58 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-58 Loading, Blocking, and Bracing of Freight Car Shipments. As...

  15. Barriers to uptake of prevention of mother-to-child transmission of HIV services among mothers of vertically infected HIV-seropositive infants in Makurdi, Nigeria

    PubMed Central

    Anígilájé, Emmanuel Ademola; Ageda, Bem Ruben; Nweke, Nnamdi Okechukwu

    2016-01-01

    Background Perinatal transmission of human immunodeficiency virus (HIV) continues in Nigeria because of the poor use of prevention of mother-to-child transmission of HIV (PMTCT) services. This study reports on the barriers preventing mothers of vertically infected HIV-seropositive infants to use the PMTCT services at the Federal Medical Centre, Makurdi, Nigeria. Methods This is a descriptive study conducted between January and April, 2014. A quantitative survey was applied to detect barriers along the PMTCT services cascade among 52 mothers of vertically infected HIV-seropositive infants. This includes 22 women who attended antenatal care at the Federal Medical Centre (designated as Group A mothers) and 30 women who did not receive any form of PMTCT service (Group B mothers). The study was supplemented with a focused group discussion involving 12 discussants from the two groups. Results In the quantitative assessment: among the Group A mothers, falling asleep was the most common reason (n=22, 100%) for missing therapeutic/prophylactic antiretroviral medicine; financial constraint (n=22, 100%) was the most common reason for antenatal care visit defaults; and a lot of the mothers (n=11, 50.0%) did not give nevirapine to their newborns because they delivered at home. Among Group B mothers, unawareness of HIV-seropositive status was the most common reason (n=28, 93.3%) given for not accessing PMTCT services. In the qualitative study: noninvolvement of male partners, stigma and discrimination experienced by HIV-seropositive mothers, financial constraints in couples, involvement of traditional birth attendants in antenatal care and delivery of HIV-infected women, unawareness of HIV-seropositive status by pregnant women, poor health system, and the lack of funding for PMTCT services at private and rural health facilities were the major barriers preventing the use of PMTCT services. Conclusion In order to reduce the missed opportunities for PMTCT interventions in Makurdi

  16. Influenza B outbreak on a cruise ship off the São Paulo Coast, Brazil.

    PubMed

    Fernandes, Eder G; de Souza, Priscila B; de Oliveira, Maria Emília B; Lima, Gisele D F; Pellini, Alessandra Cristina G; Ribeiro, Manoel Carlos S A; Sato, Helena K; Ribeiro, Ana F; Yu, Ana Lucia F

    2014-01-01

    In February 2012, crew and passengers of a cruise ship sailing off the coast of São Paulo, Brazil, were hospitalized for acute respiratory illness (ARI). A field investigation was performed to identify the disease involved and factors associated. Information on passengers and crew with ARI was obtained from the medical records of hospitalized individuals. Active case finding was performed onboard the ship. ARI was defined as the presence of one nonspecific symptom (fever, chills, myalgia, arthralgia, headache, or malaise) and one respiratory symptom (cough, nasal congestion, sore throat, or dyspnea). A case-control study was conducted among the crew. The cases were crew members with symptoms of influenza-like illness (ILI) (fever and one of the following symptoms: cough, sore throat, and dyspnea) in February 2012. The controls were asymptomatic crew members. The study identified 104 ARI cases: 54 (51.9%) crew members and 50 (49.1%) passengers. Among 11 ARI hospitalized cases, 6 had influenza B virus isolated in nasopharyngeal swab. One mortality among these patients was caused by postinfluenza Staphylococcus aureus pneumonia. The crew members housed in the two lower decks and those belonging to the 18- to 32-year-old age group were more likely to develop ILI [odds ratio (OR) = 2.39, 95% confidence interval (CI) 1.09-5.25 and OR = 3.72, CI 1.25-11.16, respectively]. In February 2012, an influenza B outbreak occurred onboard a cruise ship. Among crew members, ILI was associated with lower cabin location and younger age group. This was the first influenza outbreak detected by Brazilian public health authorities in a vessel cruising in South American waters. © 2014 International Society of Travel Medicine.

  17. Producibility in Ship Design

    DTIC Science & Technology

    1989-09-01

    INNOVATION MARINE INDUSTRY STANDARDS WELDING INDUSTRIAL ENGINEERING EDUCATION AND TRAINING THE NATIONAL SHIPBUILDING RESEARCH PROGRAM September 1989 NSRP 0310...SEP 1989 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The National Shipbuilding Research Program 1989 Ship Production Symposium...Paper No. 3: Producibility in Ship Design 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

  18. 46 CFR 52.01-35 - Auxiliary, donkey, fired thermal fluid heater, and heating boilers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... heating boilers. 52.01-35 Section 52.01-35 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-35 Auxiliary, donkey, fired thermal fluid heater, and heating boilers. (a) To determine the appropriate part of the regulations where...

  19. Pegasus Mated to B-52 Mothership - First Flight

    NASA Image and Video Library

    1989-11-09

    The Pegasus air-launched space booster is carried aloft under the right wing of NASA's B-52 carrier aircraft on its first captive flight from the Dryden Flight Research Center, Edwards, California. The first of two scheduled captive flights was completed on November 9, 1989. Pegasus is used to launch satellites into low-earth orbits cheaply. In 1997, a Pegasus rocket booster was also modified to test a hypersonic experiment (PHYSX). An experimental "glove," installed on a section of its wing, housed hundreds of temperature and pressure sensors that sent hypersonic flight data to ground tracking facilities during the experiment’s flight.

  20. A B-52H, on loan to NASA's Dryden Flight Research Center, makes a pass down the runway prior to land

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA Dryden Flight Research Center, Edwards, California, received an 'H' model B-52 Stratofortress aircraft on July 30, 2001. The B-52H will be used as an air-launch aircraft supporting NASA's flight research and advanced technology demonstration efforts. Dryden received the B-52H from the U.S. Air Force's (USAF) 23rd Bomb Squadron, 5th Bombardment Wing (Air Combat Command), located at Minot AFB, N.D. A USAF crew flew the aircraft to Dryden. The aircraft, USAF tail number 61-0025, will be loaned initially, then later transferred from the USAF to NASA. The B-52H is scheduled to leave Dryden Aug. 2 for de-militarization and Programmed Depot Maintenance (PDM) at Tinker Air Force Base (AFB), Oklahoma. The depot-level maintenance is scheduled to last about six months and includes a thorough maintenance and inspection process. The newly arrived B-52H is slated to replace Dryden's famous B-52B '008,' in the 2003-2004 timeframe. It will take about one year for the B-52H to be ready for flight research duties. This time includes PDM, construction of the new pylon, installation of the flight research instrumentation equipment, and aircraft envelope clearance flights.

  1. 46 CFR 131.530 - Abandon-ship training and drills.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Abandon-ship training and drills. 131.530 Section 131... OPERATIONS Tests, Drills, and Inspections § 131.530 Abandon-ship training and drills. (a) Material for... rescue gear (slings, baskets, stretchers) and vessel's line-throwing apparatus. (b) An abandon-ship drill...

  2. 46 CFR 131.530 - Abandon-ship training and drills.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Abandon-ship training and drills. 131.530 Section 131... OPERATIONS Tests, Drills, and Inspections § 131.530 Abandon-ship training and drills. (a) Material for... rescue gear (slings, baskets, stretchers) and vessel's line-throwing apparatus. (b) An abandon-ship drill...

  3. 46 CFR 131.530 - Abandon-ship training and drills.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Abandon-ship training and drills. 131.530 Section 131... OPERATIONS Tests, Drills, and Inspections § 131.530 Abandon-ship training and drills. (a) Material for... rescue gear (slings, baskets, stretchers) and vessel's line-throwing apparatus. (b) An abandon-ship drill...

  4. Effects of hepatitis B immunization on prevention of mother-to-infant transmission of hepatitis B virus and on the immune response of infants towards hepatitis B vaccine.

    PubMed

    Zhang, Lei; Gui, Xi-en; Teter, Caroline; Zhong, Hairong; Pang, Zhiyong; Ding, Lixiong; Li, Fengliang; Zhou, Yun; Zhang, Ling

    2014-10-21

    Combined immunization with hepatitis B immunoglobulin (HBIG) plus hepatitis B vaccine (HB vaccine) can effectively prevent perinatal transmission of hepatitis B virus (HBV). With the universal administration of HB vaccine, anti-HBs conferred by HB vaccine can be found increasingly in pregnant women, and maternal anti-HBs can be passed through the placenta. This study was designed to evaluate the effect of hepatitis B immunization on preventing mother-to-infant transmission of HBV and on the immune response of infants towards HB vaccine. From 2008 to 2013, a prospective study was conducted in 15 centers in China. HBsAg-positive pregnant women and their infants aged 8-12 months who completed immunoprophylaxis were enrolled in the study and tested for HBV markers (HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc). Antepartum administration of HBIG to HBsAg-positive women was based on individual preference. HBsAg-negative pregnant women and their infants of 7-24 months old who received HB vaccines series were enrolled and tests of their HBV markers were performed. 1202 HBsAg-positive mothers and their infants aged 8-12 months were studied and 40 infants were found to be HBsAg positive with the immunoprophylaxis failure rate of 3.3%. Infants with immunoprophylaxis failure were all born to HBeAg-positive mothers of HBV-DNA ≥6 log₁₀copies/ml. Among infants of HBeAg-positive mothers, immunoprophylaxis failure rate in vaccine plus HBIG group, 7.9% (29/367), was significantly lower than the vaccine-only group, 16.9% (11/65), p=0.021; there was no significant difference in the immunoprophylaxis failure rate whether or not antepartum HBIG was given to the pregnant woman, 10.3% (10/97) vs 9.0% (30/335), p=0.685. Anti-HBs positive rate was 56.3% (3883/6899) among HBsAg-negative pregnant women and anti-HBs positive rate was 94.2% in cord blood of anti-HBs-positive mothers. After completing the HB vaccine series, anti-HBs positive rate among infants with maternal anti

  5. Relationship of HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism with susceptibility to Takayasu arteritis: a meta-analysis.

    PubMed

    Chen, Si; Luan, Haixia; Li, Liubing; Zeng, Xiaoli; Wang, Tian; Li, Yongzhe; Yuan, Hui

    2017-01-01

    We performed a meta-analysis to determine whether combined evidence shows an association between HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism and the susceptibility to Takayasu arteritis (TA). Relevant articles dated November 2015 were acquired from the PubMed, Embase and Cochrane databases. The number of genotypes and/or alleles for HLA-B*51 and HLA-B*52 alleles and TNF-α-308 A/G polymorphism in cases and control subjects was extracted, and statistical analysis was conducted using STATA 11.2 software. We included 20 studies with 1864 TA patients and 6973 controls. The HLA-B*52 allele was found to be associated with TA (pooled OR 3.91, 95 % CI 3.22-4.74, P < 0.0001). The meta-analysis of TNF-α-308 A/G polymorphism for the A allele vs. G allele (P = 0.006) and AA + AG vs. GG (P = 0.023) revealed a significant association with TA. However, we did not find that the HLA-B*51 allele was associated with TA. This meta-analysis demonstrated that the HLA-B*52 allele and TNF-α-308 A/G polymorphism may contribute to TA susceptibility.

  6. Characterization of hepatitis B virus in Amerindian children and mothers from Amazonas State, Colombia

    PubMed Central

    Jaramillo, Carlos Mario; de La Hoz, Fernando; Porras, Alexandra; di Filippo, Diana; Choconta-Piraquive, Luz Angela; Payares, Edra; Montes, Neyla

    2017-01-01

    Background Hepatitis B Virus (HBV) infection is a worldwide public health problem. In the 1980’s a highly effective and safe vaccine against HBV was developed, although breakthrough infection still occasionally occurs because of the emergence of escape mutants. The aim of this study was to identify HBV genotypes and escape mutants in children and their mothers in Amerindian communities of the Amazonas State, Southern Colombia. Methods Blood specimens collected from children and mothers belonging to 37 Amerindian communities in Amazonas state, were screened for HBsAg and anti-HBc using ELISA. The partial region containing the S ORF was amplified by nested PCR, and amplicons were sequenced. The phylogenetic analysis was performed using the MEGA 5.05 software. Results Forty-six children (46/1275, 3.6%) and one hundred and seventy-seven mothers (177/572, 30.9%) were tested positive for the anti-HBc serological marker. Among them, 190 samples were tested for viral genome detection; 8.3% (2/31) serum samples obtained from children and 3.1% (5/159) from mothers were positive for the ORF S PCR. The predominant HBV genotype in the study population was F, subgenotype F1b; in addition, subgenotype F1a and genotype A were also characterized. Two HBV escape mutants were identified, G145R, reported worldwide, and W156*; this stop codon was identified in a child with occult HBV infection. Other mutations were found, L109R and G130E, located in critical positions of the HBsAg sequence. Conclusions This study aimed to characterize the HBV genotype F, subgenotypes F1b and F1a, and genotype A in Amerindian communities and for the first time escape mutants in Colombia. Further investigations are necessary to elucidate the frequency and the epidemiological impact of the escape mutants in the country. PMID:29016603

  7. 46 CFR 71.75-5 - Passenger Ship Safety Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 3 2011-10-01 2011-10-01 false Passenger Ship Safety Certificate. 71.75-5 Section 71.75... Passenger Ship Safety Certificate. (a) All vessels on or certificated for an international voyage are required to have a “ SOLAS Passenger Ship Safety Certificate.” (b) All such vessels shall meet the...

  8. 46 CFR 71.75-5 - Passenger Ship Safety Certificate.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 3 2013-10-01 2013-10-01 false Passenger Ship Safety Certificate. 71.75-5 Section 71.75... Passenger Ship Safety Certificate. (a) All vessels on or certificated for an international voyage are required to have a “ SOLAS Passenger Ship Safety Certificate.” (b) All such vessels shall meet the...

  9. 46 CFR 71.75-5 - Passenger Ship Safety Certificate.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 3 2014-10-01 2014-10-01 false Passenger Ship Safety Certificate. 71.75-5 Section 71.75... Passenger Ship Safety Certificate. (a) All vessels on or certificated for an international voyage are required to have a “ SOLAS Passenger Ship Safety Certificate.” (b) All such vessels shall meet the...

  10. 46 CFR 71.75-5 - Passenger Ship Safety Certificate.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 3 2012-10-01 2012-10-01 false Passenger Ship Safety Certificate. 71.75-5 Section 71.75... Passenger Ship Safety Certificate. (a) All vessels on or certificated for an international voyage are required to have a “ SOLAS Passenger Ship Safety Certificate.” (b) All such vessels shall meet the...

  11. 48 CFR 52.247-65 - F.o.b. Origin, Prepaid Freight-Small Package Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin, Prepaid... Text of Provisions and Clauses 52.247-65 F.o.b. Origin, Prepaid Freight—Small Package Shipments. As prescribed in 47.303-17(f), insert the following clause: F.o.b. Origin Prepaid Freight—Small Package...

  12. Ship Detection and Measurement of Ship Motion by Multi-Aperture Synthetic Aperture Radar

    DTIC Science & Technology

    2014-06-01

    Reconstructed periodic components of the Doppler histories shown in Fig. 27, (b) splined harmonic component amplitudes as a function of range...78 Figure 42: (a) Reconstructed periodic components of the Doppler histories shown in Figure 30, (b) Splined amplitudes of the...Figure 29 (b) Splined amplitudes of the harmonic components. ............................................ 79 Figure 44: Ship focusing by standard

  13. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Dryden Experimental Fabrication Shop's Andy Blua and Jeff Doughty make sure the new pylon for the X-38 fits precisely during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California in 1997. The 1,200-pound steel pylon, fabricated at Dryden, was an 'adapter' to allow the X-38 research vehicle to be carried aloft and launched from the bomber. The X-38 was a designed as a technology demonstrator to help develop an emergency Crew Return Vehicle for the International Space Station. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research

  14. 46 CFR 111.30-27 - Direct current ship's service switchboards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Direct current ship's service switchboards. 111.30-27... ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Switchboards § 111.30-27 Direct current ship's service switchboards. (a) Each direct current ship's service switchboard must have the equipment required by paragraphs (b...

  15. 46 CFR 111.30-27 - Direct current ship's service switchboards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Direct current ship's service switchboards. 111.30-27... ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Switchboards § 111.30-27 Direct current ship's service switchboards. (a) Each direct current ship's service switchboard must have the equipment required by paragraphs (b...

  16. Influence of mother-daughter attachment on substance use: a longitudinal study of a Latina community-based sample.

    PubMed

    De La Rosa, Mario; Huang, Hui; Rojas, Patria; Dillon, Frank R; Lopez-Quintero, Catalina; Li, Tan; Ravelo, Gira J

    2015-03-01

    Advancing our initial, cross-sectional study, which showed that adult Latinas' mother-daughter attachment relates to their substance use, the current, longitudinal study tests whether mother and daughter attachment scores at baseline predict their substance use over time. We analyzed data from a convenience sample of 133 Latina adult mothers (mean age = 52 years, SD = 10) and 133 Latina adult daughters (mean age = 27, SD = 9) at baseline and at 5-year and 6-year follow-ups after baseline (attrition rate = 16%). Multilevel longitudinal modeling was used to examine the effect of mother-daughter attachment at baseline on their substance use over time. Each unit of increase in the attachment score at baseline is associated with a 0.28 drink decrease in monthly alcohol use (p < .05) and a lower likelihood of being a heavy alcohol or other drug user [exp(β) = 0.97, p < .01] compared with average attachment score at baseline (M = 91.52, SD = 18.00). Time and older age at baseline are associated with decreased substance use. Being born outside the United States is associated with decreased risk of heavy alcohol or other drug use. Being a mother is associated with increased substance use. The findings of this longitudinal study on adult Latinas indicate that mother-daughter attachment has long-lasting effects on substance use trajectories among adult Latinas. Future research should focus on (a) investigating social and cultural factors mediating this relationship and (b) greater substance use among Latina mothers compared with daughters.

  17. Deep-water measurements of container ship radiated noise signatures and directionality.

    PubMed

    Gassmann, Martin; Wiggins, Sean M; Hildebrand, John A

    2017-09-01

    Underwater radiated noise from merchant ships was measured opportunistically from multiple spatial aspects to estimate signature source levels and directionality. Transiting ships were tracked via the Automatic Identification System in a shipping lane while acoustic pressure was measured at the ships' keel and beam aspects. Port and starboard beam aspects were 15°, 30°, and 45° in compliance with ship noise measurements standards [ANSI/ASA S12.64 (2009) and ISO 17208-1 (2016)]. Additional recordings were made at a 10° starboard aspect. Source levels were derived with a spherical propagation (surface-affected) or a modified Lloyd's mirror model to account for interference from surface reflections (surface-corrected). Ship source depths were estimated from spectral differences between measurements at different beam aspects. Results were exemplified with a 4870 and a 10 036 twenty-foot equivalent unit container ship at 40%-56% and 87% of service speeds, respectively. For the larger ship, opportunistic ANSI/ISO broadband levels were 195 (surface-affected) and 209 (surface-corrected) dB re 1 μPa 2 1 m. Directionality at a propeller blade rate of 8 Hz exhibited asymmetries in stern-bow (<6 dB) and port-starboard (<9 dB) direction. Previously reported broadband levels at 10° aspect from McKenna, Ross, Wiggins, and Hildebrand [(2012b). J. Acoust. Soc. Am. 131, 92-103] may be ∼12 dB lower than respective surface-affected ANSI/ISO standard derived levels.

  18. Optimization of the polyplanar optical display electronics for a monochrome B-52 display

    NASA Astrophysics Data System (ADS)

    DeSanto, Leonard

    1998-09-01

    The Polyplanar Optical Display (POD) is a unique display screen which can be used with any projection source. The prototype ten-inch display is two inches thick and has a matte black face which allows for high contrast images. The prototype being developed is a form, fit and functional replacement display for the B-52 aircraft which uses a monochrome ten-inch display. In order to achieve a long lifetime, the new display uses a new 200 mW green solid-state laser (10,000 hr. life) at 532 nm as its light source. To produce real-time video, the laser light is being modulated by a Digital Light Processing (DLPTM) chip manufactured by Texas Instruments (TI). In order to use the solid-state laser as the light source and also fit within the constraints of the B-52 display, the Digital Micromirror Device (DMDTM) chip is operated remotely from the Texas Instruments circuit board. In order to achieve increased brightness a monochrome digitizing interface was investigated. The operation of the DMDTM divorced from the light engine and the interfacing of the DMDTM board with the RS-170 video format specific to the B-52 aircraft will be discussed, including the increased brightness of the monochrome digitizing interface. A brief description of the electronics required to drive the new 200 mW laser is also presented.

  19. 48 CFR 52.247-44 - F.o.b. Designated Air Carrier's Terminal, Point of Importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Designated Air... CLAUSES Text of Provisions and Clauses 52.247-44 F.o.b. Designated Air Carrier's Terminal, Point of... the delivery term is f.o.b. designated air carrier's terminal, point of importation: F.o.b. Designated...

  20. 48 CFR 52.247-43 - F.o.b. Designated Air Carrier's Terminal, Point of Exportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Designated Air... CLAUSES Text of Provisions and Clauses 52.247-43 F.o.b. Designated Air Carrier's Terminal, Point of... the delivery term is f.o.b. designated air carrier's terminal, point of exportation: F.o.b. Designated...

  1. NASA's B-52B launch aircraft takes off carrying the third X-43A hypersonic research vehicle on a captive carry evaluation flight September 27, 2004

    NASA Image and Video Library

    2004-09-27

    Attached to the same B-52B mothership that once launched X-15 research aircraft in the 1960s, NASA's third X-43A performed a captive carry evaluation flight from Edwards Air Force Base, California on September 27, 2004. The X-43 remained mated to the B-52 throughout this mission, intended to check its readiness for launch scheduled later in the fall.

  2. C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development.

    PubMed

    Na, Huimin; Ponomarova, Olga; Giese, Gabrielle E; Walhout, Albertha J M

    2018-03-20

    Vitamin B12 functions as a cofactor for methionine synthase to produce the anabolic methyl donor S-adenosylmethionine (SAM) and for methylmalonyl-CoA mutase to catabolize the short-chain fatty acid propionate. In the nematode Caenorhabditis elegans, maternally supplied vitamin B12 is required for the development of offspring. However, the mechanism for exporting vitamin B12 from the mother to the offspring is not yet known. Here, we use RNAi of more than 200 transporters with a vitamin B12-sensor transgene to identify the ABC transporter MRP-5 as a candidate vitamin B12 exporter. We show that the injection of vitamin B12 into the gonad of mrp-5 deficient mothers rescues embryonic lethality in the offspring. Altogether, our findings identify a maternal mechanism for the transit of an essential vitamin to support the development of the next generation. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  3. 52. Patent steering gear, hatch and steering compass binnacle, view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. Patent steering gear, hatch and steering compass binnacle, view from starboard looking aft. Photograph by Jet Lowe, April 1988. - Ship BALCLUTHA, 2905 Hyde Street Pier, San Francisco, San Francisco County, CA

  4. 32 CFR 700.1056 - Command of a ship.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

  5. 32 CFR 700.1056 - Command of a ship.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

  6. 32 CFR 700.1056 - Command of a ship.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

  7. 32 CFR 700.1056 - Command of a ship.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

  8. 32 CFR 700.1056 - Command of a ship.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

  9. 46 CFR 147.15 - Hazardous ships' stores permitted on board vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Hazardous ships' stores permitted on board vessels. 147... HAZARDOUS SHIPS' STORES General Provisions § 147.15 Hazardous ships' stores permitted on board vessels. Unless prohibited under subpart B of this part, any hazardous material may be on board a vessel as ships...

  10. 46 CFR 147.15 - Hazardous ships' stores permitted on board vessels.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Hazardous ships' stores permitted on board vessels. 147... HAZARDOUS SHIPS' STORES General Provisions § 147.15 Hazardous ships' stores permitted on board vessels. Unless prohibited under subpart B of this part, any hazardous material may be on board a vessel as ships...

  11. 46 CFR 147.15 - Hazardous ships' stores permitted on board vessels.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Hazardous ships' stores permitted on board vessels. 147... HAZARDOUS SHIPS' STORES General Provisions § 147.15 Hazardous ships' stores permitted on board vessels. Unless prohibited under subpart B of this part, any hazardous material may be on board a vessel as ships...

  12. 46 CFR 147.15 - Hazardous ships' stores permitted on board vessels.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Hazardous ships' stores permitted on board vessels. 147... HAZARDOUS SHIPS' STORES General Provisions § 147.15 Hazardous ships' stores permitted on board vessels. Unless prohibited under subpart B of this part, any hazardous material may be on board a vessel as ships...

  13. 46 CFR 189.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Cargo Ship Safety Equipment Certificate. 189.60-10..., 1974 § 189.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the...

  14. 46 CFR 91.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Cargo Ship Safety Equipment Certificate. 91.60-10..., 1974 § 91.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the applicable...

  15. 46 CFR 91.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Cargo Ship Safety Equipment Certificate. 91.60-10..., 1974 § 91.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the applicable...

  16. 46 CFR 91.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Cargo Ship Safety Equipment Certificate. 91.60-10..., 1974 § 91.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the applicable...

  17. 46 CFR 91.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Cargo Ship Safety Equipment Certificate. 91.60-10..., 1974 § 91.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the applicable...

  18. 46 CFR 189.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Cargo Ship Safety Equipment Certificate. 189.60-10..., 1974 § 189.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the...

  19. 46 CFR 189.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Cargo Ship Safety Equipment Certificate. 189.60-10..., 1974 § 189.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the...

  20. 46 CFR 91.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Cargo Ship Safety Equipment Certificate. 91.60-10..., 1974 § 91.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the applicable...

  1. 46 CFR 189.60-10 - Cargo Ship Safety Equipment Certificate.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Cargo Ship Safety Equipment Certificate. 189.60-10..., 1974 § 189.60-10 Cargo Ship Safety Equipment Certificate. (a) All vessels on an international voyage are required to have a Cargo Ship Safety Equipment Certificate. (b) All such vessels shall meet the...

  2. (Non)Verbal Behavior of Young Stutterers and Their Mothers. Final Report.

    ERIC Educational Resources Information Center

    Conture, Edward G.

    This final report describes activities and accomplishments of a 3-year project which analyzed the speech and related behaviors of 28 young children (mean age 52.5 months) who stuttered, their mothers, and similar non-stuttering children and mothers. A loosely structured conversation between each mother and child was recorded and analyzed. In…

  3. 46 CFR 147.15 - Hazardous ships' stores permitted on board vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Hazardous ships' stores permitted on board vessels. 147.15 Section 147.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.15 Hazardous ships' stores permitted on board vessels. Unless prohibited under subpart B of this...

  4. Apolipoprotein B-52 mutation associated with hypobetalipoproteinemia is compatible with a misaligned pairing deletion mechanism.

    PubMed

    Groenewegen, W A; Krul, E S; Schonfeld, G

    1993-06-01

    We have identified a new truncation of apoB in a large kindred with hypobetalipoproteinemia that arose by an ambiguous deletion of one of four different groups of base-pairs. Eleven affected members of the kindred had total cholesterols (C) of 114 +/- 28, LDL-Cs of 46 +/- 21, and apoBs of 47 +/- 25 (all in mg/dl, mean +/- SD). These levels were lower (P < 0.0001) than in 15 unaffected relatives. On Western blotting, apoB-100 and a second major band corresponding to apoB-52 were seen in the affected individuals. The majority of the plasma apoB-52 was associated with a smaller than normal low density lipoprotein (LDL) particle. The molecular basis for this apoB-52 truncation is a 5-bp deletion, converting the sequence between cDNA nucleotide 7276 and 7283 from 5'-AAGTTAAG-3' into the mutant sequence 5'-AAG-3'. This results in a frameshift starting at amino acid residue 2357 and a termination codon at amino acid residue 2362. Deletion of one of four different groups of five consecutive bases, i.e., AAGTT, AGTTA, GTTAA, and TTAAG, all result in the same mutant sequence. Thus, the precise deletion is ambiguous. We propose that a misaligned pairing mechanism involving repeat sequences is compatible with this deletion mutation. We have noted similar ambiguous deletions associated with apoB-37, apoB-40, and a number of single base deletions and some may also be explained by a misaligned pairing mechanism. Small ambiguous deletions appear to constitute a major proportion of the apoB gene mutation spectrum suggesting that it may be a suitable model for studying the mechanisms of such mutations.

  5. 78 FR 26249 - Drawbridge Operation Regulation; Lake Washington Ship Canal, Seattle, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ...The Coast Guard has issued a temporary deviation from the operating schedule that governs the Montlake Bridge across the Lake Washington Ship Canal, mile 5.2, at Seattle, WA, and the University Bridge across the Lake Washington Ship Canal, mile 4.3, at Seattle, WA. This deviation is necessary to accommodate the ``Beat the Bridge'' foot race. This deviation allows the bridges to remain in the closed position to allow safe movement of event participants.

  6. Optimization of the polyplanar optical display electronics for a monochrome B-52 display

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeSanto, L.

    The Polyplanar Optical Display (POD) is a unique display screen which can be used with any projection source. The prototype ten-inch display is two inches thick and has a matte black face which allows for high contrast images. The prototype being developed is a form, fit and functional replacement display for the B-52 aircraft which uses a monochrome ten-inch display. In order to achieve a long lifetime, the new display uses a new 200 mW green solid-state laser (10,000 hr. life) at 532 nm as its light source. To produce real-time video, the laser light is being modulated by amore » Digital Light Processing (DLP{trademark}) chip manufactured by Texas Instruments (TI). In order to use the solid-state laser as the light source and also fit within the constraints of the B-52 display, the Digital Micromirror Device (DMD{trademark}) chip is operated remotely from the Texas Instruments circuit board. In order to achieve increased brightness a monochrome digitizing interface was investigated. The operation of the DMD{trademark} divorced from the light engine and the interfacing of the DMD{trademark} board with the RS-170 video format specific to the B-52 aircraft will be discussed, including the increased brightness of the monochrome digitizing interface. A brief description of the electronics required to drive the new 200 mW laser is also presented.« less

  7. X-15 launch from B-52 mothership

    NASA Technical Reports Server (NTRS)

    1959-01-01

    This photo illustrates how the X-15 rocket-powered aircraft was taken aloft under the wing of a B-52. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at 45,000 ft and a speed of about 500 mph. This was one of the early powered flights using a pair of XLR-11 engines (until the XLR-99 became available). The X-15 was a rocket-powered aircraft 50 ft long with a wingspan of 22 ft. It was a missile-shaped vehicle with an unusual wedge-shaped vertical tail, thin stubby wings, and unique fairings that extended along the side of the fuselage. The X-15 weighed about 14,000 lb empty and approximately 34,000 lb at launch. The XLR-99 rocket engine, manufactured by Thiokol Chemical Corp., was pilot controlled and was capable of developing 57,000 lb of rated thrust (actual thrust reportedly climbed to 60,000 lb). North American Aviation built three X-15 aircraft for the program. The X-15 research aircraft was developed to provide in-flight information and data on aerodynamics, structures, flight controls, and the physiological aspects of high-speed, high-altitude flight. A follow-on program used the aircraft as a testbed to carry various scientific experiments beyond the Earth's atmosphere on a repeated basis. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls such as rudder surfaces on the vertical stabilizers to control yaw and canted horizontal surfaces on the tail to control pitch when moving in synchronization or roll when moved differentially. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at 45,000 ft and a speed of about 500 mph. Depending on the mission, the rocket engine provided thrust for

  8. 48 CFR 52.247-55 - F.o.b. Point for Delivery of Government-Furnished Property.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Point for Delivery... Text of Provisions and Clauses 52.247-55 F.o.b. Point for Delivery of Government-Furnished Property. As prescribed in 47.305-12(a)(2), insert the following clause: F.o.b. Point for Delivery of Government-Furnished...

  9. NASA's B-52B launch aircraft takes off carrying the second X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on March 27, 2004

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif., on March 27, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 7.

  10. NASA's B-52B launch aircraft takes off carrying the third X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

  11. Single Mother Parenting and Adolescent Psychopathology.

    PubMed

    Daryanani, Issar; Hamilton, Jessica L; Abramson, Lyn Y; Alloy, Lauren B

    2016-10-01

    Children raised in single-mother families are at increased risk for psychopathology, but the mechanisms that help explain this relationship are understudied. In a community sample of diverse adolescents (N = 385, 52 % female, 48 % Caucasian) and their mothers, we hypothesized that single mothers would be more likely than cohabitating mothers to engage in negative parenting behaviors, which would predict adolescent psychopathology prospectively. Single mothers were more likely to engage in psychologically controlling behaviors, which predicted to their adolescent offspring experiencing higher rates of depressive symptoms and externalizing disorders. Girls were more susceptible to depressive symptoms via psychologically controlling parenting than boys in single-mother families. Further, single mothers were more likely to engage in rejecting parenting behaviors, which predicted to a higher prevalence of adolescent externalizing disorders. Surprisingly, rejection in single-mother families predicted to less severe anxiety symptoms in adolescents relative to two-parent families. It is likely that single mothers are not inherently inferior parents relative to cohabitating mothers; rather, their parenting practices are often compromised by a myriad of demands and stressors. Consistent with this postulate, low socioeconomic status was associated with single motherhood and negative parenting behaviors. Clinical implications and study limitations are discussed.

  12. Single Mother Parenting and Adolescent Psychopathology

    PubMed Central

    Daryanai, Issar; Hamilton, Jessica L.; Abramson, Lyn Y.; Alloy, Lauren B.

    2017-01-01

    Children raised in single-mother families are at increased risk for psychopathology, but the mechanisms that help explain this relationship are understudied. In a community sample of diverse adolescents (N= 385, 52% female, 48% Caucasian) and their mothers, we hypothesized that single mothers would be more likely than cohabitating mothers to engage in negative parenting behaviors, which would predict adolescent psychopathology prospectively. Single mothers were more likely to engage in psychologically controlling behaviors, which predicted to their adolescent offspring experiencing higher rates of depressive symptoms and externalizing disorders. Girls were more susceptible to depressive symptoms via psychologically controlling parenting than boys in single-mother families. Further, single mothers were more likely to engage in rejecting parenting behaviors, which predicted to a higher prevalence of adolescent externalizing disorders. Surprisingly, rejection in single-mother families predicted to less severe anxiety symptoms in adolescents relative to two-parent families. It is likely that single mothers are not inherently inferior parents relative to cohabitating mothers; rather, their parenting practices are often compromised by a myriad of demands and stressors. Consistent with this postulate, low socioeconomic status was associated with single motherhood and negative parenting behaviors. Clinical implications and study limitations are discussed. PMID:26767832

  13. The impact of "Option B" on HIV transmission from mother to child in Rwanda: An interrupted time series analysis.

    PubMed

    Abimpaye, Monique; Kirk, Catherine M; Iyer, Hari S; Gupta, Neil; Remera, Eric; Mugwaneza, Placidie; Law, Michael R

    2018-01-01

    Nearly a quarter of a million children have acquired HIV, prompting the implementation of new protocols-Option B and B+-for treating HIV+ pregnant women. While efficacy has been demonstrated in randomized trials, there is limited real-world evidence on the impact of these changes. Using longitudinal, routinely collected data we assessed the impact of the adoption of WHO Option B in Rwanda on mother to infant transmission. We used interrupted time series analysis to evaluate the impact of Option B on mother-to-child HIV transmission in Rwanda. Our primary outcome was the proportion of HIV tests in infants with positive results at six weeks of age. We included data for 20 months before and 22 months after the 2010 policy change. Of the 15,830 HIV tests conducted during our study period, 392 tested positive. We found a significant decrease in both the level (-2.08 positive tests per 100 tests conducted, 95% CI: -2.71 to -1.45, p < 0.001) and trend (-0.11 positive tests per 100 tests conducted per month, 95% CI: -0.16 to -0.07, p < 0.001) of test positivity. This represents an estimated 297 fewer children born without HIV in the post-policy period or a 46% reduction in HIV transmission from mother to child. The adoption of Option B in Rwanda contributed to an immediate decrease in the rate of HIV transmission from mother to child. This suggests other countries may benefit from adopting these WHO guidelines.

  14. 48 CFR 52.247-33 - F.o.b. Origin, With Differentials.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., and placed on, the carrier's wharf (at shipside, within reach of the ship's loading tackle, when the shipping point is within a port area having water transportation service) or the carrier's freight station... lading shall show— (i) A description of the shipment in terms of the governing freight classification or...

  15. F-15 RPRV Attached Under the Wing of the B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This photograph shows one of NASA's 3/8th-scale F-15 remotely piloted research vehicles under the wing of the B-52 mothership in flight during 1973, the year that the research program began. The vehicle was used to make stall-spin studies of the F-15 shape before the actual F-15s began their flight tests. B-52 Project Description: NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle

  16. NF-KappaB2/p52 Activation and Androgen Receptor Signaling in Prostate Cancer

    DTIC Science & Technology

    2011-08-01

    biosynthetic enzymes including AKR1C3, CYP17A1, HSD3B2, and SRD5A1 were found to be elevated in CaP cells expressing NF-kappaB2/p52. Luciferase assays...RESULTS: Expression levels of androgen biosynthetic enzymes including AKR1C3, CYP17A1, HSD3B2, and SRD5A1 were found to be elevated in CaP cells

  17. Associations between Observed Mother-Adolescent Interactions and Adolescent Information Management

    ERIC Educational Resources Information Center

    Rote, Wendy M.; Smetana, Judith G.; Campione-Barr, Nicole; Villalobos, Myriam; Tasopoulos-Chan, Marina

    2012-01-01

    Associations between observed mother-adolescent interactions during a conflict task and adolescents' information management strategies were examined in 108 primarily middle class, European-American adolescents (M = 13.80 years, SD = 1.52) and their mothers. Teens who communicated more clearly disclosed more about personal and multifaceted…

  18. X-15 ship #3 on lakebed

    NASA Technical Reports Server (NTRS)

    1962-01-01

    pilot controlled and was capable of developing 57,000 lb of thrust. North American Aviation built three X-15 aircraft for the program. The X-15 research aircraft was developed to provide in-flight information and data on aerodynamics, structures, flight controls, and the physiological aspects of high-speed, high-altitude flight. A follow-on program used the aircraft as a testbed to carry various scientific experiments beyond the Earth's atmosphere on a repeated basis. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls such as rudder surfaces on the vertical stabilizers to control yaw and movable horizontal stabilizers to control pitch when moving in synchronization or roll when moved differentially. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at 45,000 ft and a speed of about 500 mph. Depending on the mission, the rocket engine provided thrust for the first 80 to 120 sec of flight. The remainder of the normal 10 to 11 min. flight was powerless and ended with a 200-mph glide landing. Generally, one of two types of X-15 flight profiles was used; a high-altitude flight plan that called for the pilot to maintain a steep rate of climb, or a speed profile that called for the pilot to push over and maintain a level altitude. The X-15 was flown over a period of nearly 10 years -- June 1959 to Oct. 1968 -- and set the world's unofficial speed and altitude records of 4,520 mph or Mach 6.7 (set by Ship #2) and 354,200 ft (set by Ship #3) in a program to investigate all aspects of manned hypersonic flight. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini,and Apollo manned

  19. Ship noise extends to frequencies used for echolocation by endangered killer whales

    PubMed Central

    Veirs, Val; Wood, Jason D.

    2016-01-01

    Combining calibrated hydrophone measurements with vessel location data from the Automatic Identification System, we estimate underwater sound pressure levels for 1,582 unique ships that transited the core critical habitat of the endangered Southern Resident killer whales during 28 months between March, 2011, and October, 2013. Median received spectrum levels of noise from 2,809 isolated transits are elevated relative to median background levels not only at low frequencies (20–30 dB re 1 µPa2/Hz from 100 to 1,000 Hz), but also at high frequencies (5–13 dB from 10,000 to 96,000 Hz). Thus, noise received from ships at ranges less than 3 km extends to frequencies used by odontocetes. Broadband received levels (11.5–40,000 Hz) near the shoreline in Haro Strait (WA, USA) for the entire ship population were 110 ± 7 dB re 1 µPa on average. Assuming near-spherical spreading based on a transmission loss experiment we compute mean broadband source levels for the ship population of 173 ± 7 dB re 1 µPa 1 m without accounting for frequency-dependent absorption. Mean ship speed was 7.3 ± 2.0 m/s (14.1 ± 3.9 knots). Most ship classes show a linear relationship between source level and speed with a slope near +2 dB per m/s (+1 dB/knot). Spectrum, 1/12-octave, and 1/3-octave source levels for the whole population have median values that are comparable to previous measurements and models at most frequencies, but for select studies may be relatively low below 200 Hz and high above 20,000 Hz. Median source spectrum levels peak near 50 Hz for all 12 ship classes, have a maximum of 159 dB re 1 µPa2/Hz @ 1 m for container ships, and vary between classes. Below 200 Hz, the class-specific median spectrum levels bifurcate with large commercial ships grouping as higher power noise sources. Within all ship classes spectrum levels vary more at low frequencies than at high frequencies, and the degree of variability is almost halved for classes that have smaller speed standard

  20. Ship noise extends to frequencies used for echolocation by endangered killer whales.

    PubMed

    Veirs, Scott; Veirs, Val; Wood, Jason D

    2016-01-01

    Combining calibrated hydrophone measurements with vessel location data from the Automatic Identification System, we estimate underwater sound pressure levels for 1,582 unique ships that transited the core critical habitat of the endangered Southern Resident killer whales during 28 months between March, 2011, and October, 2013. Median received spectrum levels of noise from 2,809 isolated transits are elevated relative to median background levels not only at low frequencies (20-30 dB re 1 µPa(2)/Hz from 100 to 1,000 Hz), but also at high frequencies (5-13 dB from 10,000 to 96,000 Hz). Thus, noise received from ships at ranges less than 3 km extends to frequencies used by odontocetes. Broadband received levels (11.5-40,000 Hz) near the shoreline in Haro Strait (WA, USA) for the entire ship population were 110 ± 7 dB re 1 µPa on average. Assuming near-spherical spreading based on a transmission loss experiment we compute mean broadband source levels for the ship population of 173 ± 7 dB re 1 µPa 1 m without accounting for frequency-dependent absorption. Mean ship speed was 7.3 ± 2.0 m/s (14.1 ± 3.9 knots). Most ship classes show a linear relationship between source level and speed with a slope near +2 dB per m/s (+1 dB/knot). Spectrum, 1/12-octave, and 1/3-octave source levels for the whole population have median values that are comparable to previous measurements and models at most frequencies, but for select studies may be relatively low below 200 Hz and high above 20,000 Hz. Median source spectrum levels peak near 50 Hz for all 12 ship classes, have a maximum of 159 dB re 1 µPa(2)/Hz @ 1 m for container ships, and vary between classes. Below 200 Hz, the class-specific median spectrum levels bifurcate with large commercial ships grouping as higher power noise sources. Within all ship classes spectrum levels vary more at low frequencies than at high frequencies, and the degree of variability is almost halved for classes that have smaller speed standard

  1. 46 CFR 153.483 - Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1, 1986...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.483 Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1...

  2. 46 CFR 153.480 - Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986: Categories...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.480 Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986...

  3. 46 CFR 153.480 - Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986: Categories...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.480 Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986...

  4. 46 CFR 153.480 - Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986: Categories...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.480 Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986...

  5. 46 CFR 153.483 - Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1, 1986...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.483 Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1...

  6. 46 CFR 153.480 - Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986: Categories...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.480 Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986...

  7. 46 CFR 153.480 - Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986: Categories...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.480 Stripping quantity for Category B and C NLS tanks on ships built after June 30, 1986...

  8. 46 CFR 153.483 - Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1, 1986...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.483 Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1...

  9. 46 CFR 153.483 - Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1, 1986...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.483 Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1...

  10. 46 CFR 153.483 - Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1, 1986...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Design and Equipment for Pollution Control § 153.483 Restricted voyage waiver for Category B and C NLS tanks on ships built before July 1...

  11. 46 CFR 111.52-3 - Systems below 1500 kilowatts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-3 Systems below 1500 kilowatts. The... maximum short-circuit current of a direct current system must be assumed to be 10 times the aggregate...

  12. 46 CFR 111.52-3 - Systems below 1500 kilowatts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Calculation of Short-Circuit Currents § 111.52-3 Systems below 1500 kilowatts. The... maximum short-circuit current of a direct current system must be assumed to be 10 times the aggregate...

  13. Hepatitis B vaccination coverage and risk factors associated with incomplete vaccination of children born to hepatitis B surface antigen-positive mothers, Denmark, 2006 to 2010.

    PubMed

    Kunoee, Asja; Nielsen, Jens; Cowan, Susan

    2016-01-01

    In Denmark, universal screening of pregnant women for hepatitis B has been in place since November 2005, with the first two years as a trial period with enhanced surveillance. It is unknown what the change to universal screening without enhanced surveillance has meant for vaccination coverage among children born to hepatitis B surface antigen (HBsAg)-positive mothers and what risk factors exist for incomplete vaccination. This retrospective cohort study included 699 children of mothers positive for HBsAg. Information on vaccination and risk factors was collected from central registers. In total, 93% (651/699) of the children were vaccinated within 48 hours of birth, with considerable variation between birthplaces. Only 64% (306/475) of the children had received all four vaccinations through their general practitioner (GP) at the age of two years, and 10% (47/475) of the children had received no hepatitis B vaccinations at all. Enhanced surveillance was correlated positively with coverage of birth vaccination but not with coverage at the GP. No or few prenatal examinations were a risk factor for incomplete vaccination at the GP. Maternity wards and GPs are encouraged to revise their vaccination procedures and routines for pregnant women, mothers with chronic HBV infection and their children.

  14. Early childhood transmission of hepatitis B prior to the first hepatitis B vaccine dose is rare among babies born to HIV-infected and non-HIV infected mothers in Gulu, Uganda

    PubMed Central

    Van Geertruyden, J.P.; Ssenyonga, R.; Opio, C.K.; Kaducu, J.M.; Sempa, J.B.; Colebunders, R.; Ocama, P.

    2017-01-01

    Background Hepatitis B (HBV) in sub-Saharan Africa is believed to be horizontally acquired. However, because of the high HBV prevalence in northern Uganda, no hepatitis B vaccination at birth and no access to HBV immunoglobulin, we hypothesize that vertical transmission also could also play an important role. We therefore investigated the incidence of HBV among babies presenting for their first HBV vaccine dose in Gulu, Uganda. Methods We recruited mothers and their babies (at least 6-week old) presenting for their postnatal care and first HBV vaccine dose respectively. Socio-demographic and risk factors for HBV transmission were recorded. Mothers were tested for Hepatitis B core antibody (anti-HBc-IgG) and hepatitis B surface antigen (HBsAg). HBsAg-positive sera were tested for hepatitis B e antigen (HBeAg) and HBV viral load (HBVDNA). Babies were tested for HBsAg at presentation and at the last immunization visit. A sample of HBsAg-negative babies were tested for HBVDNA. Incident HBV infection was defined by either a positive HBsAg or HBVDNA test. Chi-square or fisher's exact tests were utilized to investigate associations and t-tests or Wilcoxon rank-sum test for continuous differences. Results We recruited 612 mothers, median age 23 years (IQR 20–28). 53 (8.7%) were HBsAg-positive and 339 (61.5%) were anti-HBc-IgG-positive. Ten (18.9%) of the HBsAg-positive mothers were HBeAg-positive. Median HBVDNA levels of HBV-infected mothers was 5.7log (IQR 4.6–7.0) IU/mL with 9 (17.6%) having levels ≥105 IU/mL. Eighty (13.3%) mothers were HIV-infected of whom 9 (11.5%) were co-infected with HBV. No baby tested HBsAg or HBVDNA positive. Conclusion Vertical transmission does not seem to contribute substantially to the high HBV endemicity in northern Uganda. The current practice of administering the first HBV vaccine to babies in Uganda at six weeks of age may be adequate in control of HBV transmission. PMID:28434689

  15. The National Shipbuilding Research Program. 1989 Ship Production Symposium. Paper No. 3: Producibility in Ship Design

    DTIC Science & Technology

    1989-09-01

    INNOVATION MARINE INDUSTRY STANDARDS WELDING INDUSTRIAL ENGINEERING EDUCATION AND TRAINING THE NATIONAL SHIPBUILDING RESEARCH PROGRAM September 1989 NSRP 0310...SEP 1989 2. REPORT TYPE 3. DATES COVERED 00-00-1989 to 00-00-1989 4. TITLE AND SUBTITLE The National Shipbuilding Research Program . 1989 Ship...Production Symposium, Paper No. 3: Producibility in Ship Design 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

  16. 46 CFR 52.25-7 - Electric boilers (modifies PEB-1 through PEB-19).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-7 Electric boilers (modifies PEB-1 through PEB-19). Electric boilers required to comply with this part must meet the applicable provisions in this part and the... 46 Shipping 2 2011-10-01 2011-10-01 false Electric boilers (modifies PEB-1 through PEB-19). 52.25...

  17. 46 CFR 52.25-7 - Electric boilers (modifies PEB-1 through PEB-19).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-7 Electric boilers (modifies PEB-1 through PEB-19). Electric boilers required to comply with this part must meet the applicable provisions in this part and the... 46 Shipping 2 2010-10-01 2010-10-01 false Electric boilers (modifies PEB-1 through PEB-19). 52.25...

  18. 46 CFR 52.25-7 - Electric boilers (modifies PEB-1 through PEB-19).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-7 Electric boilers (modifies PEB-1 through PEB-19). Electric boilers required to comply with this part must meet the applicable provisions in this part and the... 46 Shipping 2 2012-10-01 2012-10-01 false Electric boilers (modifies PEB-1 through PEB-19). 52.25...

  19. 46 CFR 52.25-7 - Electric boilers (modifies PEB-1 through PEB-19).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-7 Electric boilers (modifies PEB-1 through PEB-19). Electric boilers required to comply with this part must meet the applicable provisions in this part and the... 46 Shipping 2 2014-10-01 2014-10-01 false Electric boilers (modifies PEB-1 through PEB-19). 52.25...

  20. 46 CFR 52.25-7 - Electric boilers (modifies PEB-1 through PEB-19).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-7 Electric boilers (modifies PEB-1 through PEB-19). Electric boilers required to comply with this part must meet the applicable provisions in this part and the... 46 Shipping 2 2013-10-01 2013-10-01 false Electric boilers (modifies PEB-1 through PEB-19). 52.25...

  1. Effect of HBIG combined with hepatitis B vaccine on blocking HBV transmission between mother and infant and its effect on immune cells.

    PubMed

    Gong, Junling; Liu, Xing

    2018-01-01

    The effect of hepatitis B immune globulin (HBIG) combined with hepatitis B vaccine on blocking hepatitis B virus (HBV) transmission between mother and infant and its effect on immune cells were studied. Ninety newborn infants confirmed to be HBV surface antigen (HBsAg)-positive were divided equally into three groups. Group A newborns received the hepatitis B vaccine at 0, 1 and 6 months after birth (10 µg/time). Group B newborns received an intramuscular injection of 100 IU HBIG 2 h after birth before the same treatment as group A. Mothers of group C newborns received three gluteus maxinus injections of 200 IU HBIG. The newborns in group C got the same treatment as group B. The blocking effect of HBV transmission between mother and infant was evaluated, and cell immune function was assessed. There were significant differences in comparison of blocking success rates between group A and B, and between group A and C as well (p<0.05). At the end of 12 months follow-up, the CD4 + level and CD4 + /CD8 + ratio in group C were higher thanthose in group A and B (p<0.05). In addition, the level of CD8 + T lymphocyte in group C was lower than those in group A and B (p<0.05). In comparison of levels of CD4 + T lymphocyte at the end of 12 months follow-up and 24 h after birth, the differences were significant (p<0.05) in bothgroup B and C. The differences of IFN-γ levels betweengroups B/C and group A were significant (p<0.05). Forthose newborn infants born to mothers who were positivefor both HBsAg and HBeAg, HBIG intervention formothers during late pregnancy, together with combinedtreatment of HBIG and hepatitis B vaccine for infants, gavebetter blocking result of HBV transmission.

  2. 46 CFR 42.05-63 - Ship(s) and vessel(s).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Ship(s) and vessel(s). 42.05-63 Section 42.05-63 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Definition of Terms Used in This Subchapter § 42.05-63 Ship(s) and vessel(s). The terms ship(s...

  3. 46 CFR 42.05-63 - Ship(s) and vessel(s).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Ship(s) and vessel(s). 42.05-63 Section 42.05-63 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Definition of Terms Used in This Subchapter § 42.05-63 Ship(s) and vessel(s). The terms ship(s...

  4. 46 CFR 42.05-63 - Ship(s) and vessel(s).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Ship(s) and vessel(s). 42.05-63 Section 42.05-63 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Definition of Terms Used in This Subchapter § 42.05-63 Ship(s) and vessel(s). The terms ship(s...

  5. 46 CFR 42.05-63 - Ship(s) and vessel(s).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Ship(s) and vessel(s). 42.05-63 Section 42.05-63 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Definition of Terms Used in This Subchapter § 42.05-63 Ship(s) and vessel(s). The terms ship(s...

  6. Correlations between Maternal, Breast Milk, and Infant Vitamin B12 Concentrations among Mother-Infant Dyads in Vancouver, Canada and Prey Veng, Cambodia: An Exploratory Analysis.

    PubMed

    Chebaya, Philip; Karakochuk, Crystal D; March, Kaitlin M; Chen, Nancy N; Stamm, Rosemary A; Kroeun, Hou; Sophonneary, Prak; Borath, Mam; Shahab-Ferdows, Setareh; Hampel, Daniela; Barr, Susan I; Lamers, Yvonne; Houghton, Lisa A; Allen, Lindsay H; Green, Tim J; Whitfield, Kyly C

    2017-03-12

    Vitamin B12 plays an essential role in fetal and infant development. In regions where animal source food consumption is low and perinatal supplementation is uncommon, infants are at risk of vitamin B12 deficiency. In this secondary analysis, we measured total vitamin B12 concentrations in maternal and infant serum/plasma and breast milk among two samples of mother-infant dyads in Canada (assessed at 8 weeks post-partum) and in Cambodia (assessed between 3-27 weeks post-partum). Canadian mothers ( n = 124) consumed a daily vitamin B12-containing multiple micronutrient supplement throughout pregnancy and lactation; Cambodian mothers ( n = 69) were unsupplemented. The maternal, milk, and infant total vitamin B12 concentrations (as geometric means (95% CI) in pmol/L) were as follows: in Canada, 698 (648,747), 452 (400, 504), and 506 (459, 552); in Cambodia, 620 (552, 687), 317 (256, 378), and 357 (312, 402). The majority of participants were vitamin B12 sufficient (serum/plasma total B12 > 221 pmol/L): 99% and 97% of mothers and 94% and 84% of infants in Canada and Cambodia, respectively. Among the Canadians, maternal, milk, and infant vitamin B12 were all correlated ( p < 0.05); only maternal and infant vitamin B12 were correlated among the Cambodians ( p < 0.001).

  7. Scope of Work for Mk 28 FI Bomb and B52 Drop Test Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Draper, E.H.

    1965-10-04

    List of principles & responsibilities of this Sandia/AEC & Air Force joint program for verifying the functionability of the W28/AGM-28A/B-52 weapon system under actual routine handling, assembling, and firing during a stockpile-to-target sequence.

  8. 46 CFR 31.40-10 - Cargo Ship Safety Equipment Certificate-T/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo Ship Safety Equipment Certificate-T/ALL. 31.40-10... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-10 Cargo Ship... Cargo Ship Safety Equipment Certificate. (b) All such tankships shall meet the applicable requirements...

  9. 46 CFR 31.40-10 - Cargo Ship Safety Equipment Certificate-T/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo Ship Safety Equipment Certificate-T/ALL. 31.40-10... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-10 Cargo Ship... Cargo Ship Safety Equipment Certificate. (b) All such tankships shall meet the applicable requirements...

  10. 46 CFR 31.40-10 - Cargo Ship Safety Equipment Certificate-T/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo Ship Safety Equipment Certificate-T/ALL. 31.40-10... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-10 Cargo Ship... Cargo Ship Safety Equipment Certificate. (b) All such tankships shall meet the applicable requirements...

  11. 46 CFR 31.40-10 - Cargo Ship Safety Equipment Certificate-T/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo Ship Safety Equipment Certificate-T/ALL. 31.40-10... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-10 Cargo Ship... Cargo Ship Safety Equipment Certificate. (b) All such tankships shall meet the applicable requirements...

  12. 46 CFR 31.40-10 - Cargo Ship Safety Equipment Certificate-T/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo Ship Safety Equipment Certificate-T/ALL. 31.40-10... CERTIFICATION Certificates Under International Convention for Safety of Life at Sea, 1974 § 31.40-10 Cargo Ship... Cargo Ship Safety Equipment Certificate. (b) All such tankships shall meet the applicable requirements...

  13. The X-38 vehicle #131R arrives at NASA Dryden Flight Research Center

    NASA Image and Video Library

    2000-07-11

    The X-38 Vehicle 131R, intended to prove the utility of a "lifeboat" crew return vehicle to bring crews home from the International Space Station in the event of an emergency, was unloaded from NASA's Super Guppy transport aircraft on July 11, 2000. The newest X-38 version arrived at Dryden for drop tests from NASA's venerable B-52 mother ship. The tests will evaluate a 7,500 square-foot parafoil intended to permit the crew return vehicle to return from space and land in the length of a football field.

  14. The X-38 vehicle #131R arrives at NASA Dryden Flight Research Center

    NASA Image and Video Library

    2000-07-11

    The X-38 Vehicle 131R, intended to prove the utility of a "lifeboat" crew return vehicle to bring crews home from the International Space Station in the event of an emergency, was unloaded from NASA's Super Guppy transport aircraft on July 11, 2000. The newest X-38 version arrived at Dryden for drop tests from NASA's venerable B-52 mother ship. The tests will evaluate a 7,500 square-foot parafoil intended to permit the CRV to return from space and land in the length of a football field.

  15. The X-38 vehicle #131R arrives at NASA Dryden Flight Research Center

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The X-38 Vehicle 131R, intended to prove the utility of a 'lifeboat' crew return vehicle to bring crews home from the International Space Station in the event of an emergency, was unloaded from NASA's Super Guppy transport aircraft on July 11, 2000. The newest X-38 version arrived at Dryden for drop tests from NASA's venerable B-52 mother ship. The tests will evaluate a 7,500 square-foot parafoil intended to permit the CRV to return from space and land in the length of a football field.

  16. The X-38 vehicle #131R arrives at NASA Dryden Flight Research Center

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The X-38 Vehicle 131R, intended to prove the utility of a 'lifeboat' crew return vehicle to bring crews home from the International Space Station in the event of an emergency, was unloaded from NASA's Super Guppy transport aircraft on July 11, 2000. The newest X-38 version arrived at Dryden for drop tests from NASA's venerable B-52 mother ship. The tests will evaluate a 7,500 square-foot parafoil intended to permit the crew return vehicle to return from space and land in the length of a football field.

  17. An Arsenal Ship Design

    DTIC Science & Technology

    1996-12-01

    151 B. PROPULSION PLANT SELECTION....................................................................... 152 ix C. PROPULSION PLANT LAYOUT...155 D. ELECTRICAL PLANT SELECTION...designed into the hull and power plant and once finalized is only a function of how many miles the ship is to be driven. Decision trade- offs are to

  18. Comparative cost-effectiveness of Option B+ for prevention of mother-to-child transmission of HIV in Malawi.

    PubMed

    Tweya, Hannock; Keiser, Olivia; Haas, Andreas D; Tenthani, Lyson; Phiri, Sam; Egger, Matthias; Estill, Janne

    2016-03-27

    To estimate the cost-effectiveness of prevention of mother-to-child transmission (MTCT) of HIV with lifelong antiretroviral therapy (ART) for pregnant and breastfeeding women ('Option B+') compared with ART during pregnancy or breastfeeding only unless clinically indicated ('Option B'). Mathematical modelling study of first and second pregnancy, informed by data from the Malawi Option B+ programme. Individual-based simulation model. We simulated cohorts of 10 000 women and their infants during two subsequent pregnancies, including the breastfeeding period, with either Option B+ or B. We parameterized the model with data from the literature and by analysing programmatic data. We compared total costs of antenatal and postnatal care, and lifetime costs and disability-adjusted life-years of the infected infants between Option B+ and Option B. During the first pregnancy, 15% of the infants born to HIV-infected mothers acquired the infection. With Option B+, 39% of the women were on ART at the beginning of the second pregnancy, compared with 18% with Option B. For second pregnancies, the rates MTCT were 11.3% with Option B+ and 12.3% with Option B. The incremental cost-effectiveness ratio comparing the two options ranged between about US$ 500 and US$ 1300 per DALY averted. Option B+ prevents more vertical transmissions of HIV than Option B, mainly because more women are already on ART at the beginning of the next pregnancy. Option B+ is a cost-effective strategy for PMTCT if the total future costs and lost lifetime of the infected infants are taken into account.

  19. 46 CFR 42.05-63 - Ship(s) and vessel(s).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Ship(s) and vessel(s). 42.05-63 Section 42.05-63... BY SEA Definition of Terms Used in This Subchapter § 42.05-63 Ship(s) and vessel(s). The terms ship(s) and vessel(s) are interchangeable or synonymous words, and include every description of watercraft...

  20. 10 CFR 52.303 - Criminal penalties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the sections listed in paragraph (b) of this section. (b) The regulations in part 52 that are not... 10 Energy 2 2012-01-01 2012-01-01 false Criminal penalties. 52.303 Section 52.303 Energy NUCLEAR... Enforcement § 52.303 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

  1. 10 CFR 52.303 - Criminal penalties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the sections listed in paragraph (b) of this section. (b) The regulations in part 52 that are not... 10 Energy 2 2010-01-01 2010-01-01 false Criminal penalties. 52.303 Section 52.303 Energy NUCLEAR... Enforcement § 52.303 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

  2. 7 CFR 984.472 - Reports of merchantable walnuts shipped.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE... shipped; whether they were shipped into domestic or export channels; and for exports, the quantity by... remainder of that marketing year. (b) Reports of walnuts purchased directly from growers by handlers who are...

  3. Pegasus Engine Ignites after Drop from B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Against the midnight blue of a high-altitude sky, Orbital Sciences' Pegasus winged rocket booster ignites after being dropped from NASA's B-52 mothership on a July 1991 flight. A NASA chase plane for the flight is also visible above the rocket and below the B-52. Pegasus is an air-launched space booster produced by Orbital Sciences Corporation and Hercules Aerospace Company (initially; later, Alliant Tech Systems) to provide small satellite users with a cost-effective, flexible, and reliable method for placing payloads into low earth orbit. Pegasus has been used to launch a number of satellites and the PHYSX experiment. That experiment consisted of a smooth glove installed on the first-stage delta wing of the Pegasus. The glove was used to gather data at speeds of up to Mach 8 and at altitudes approaching 200,000 feet. The flight took place on October 22, 1998. The PHYSX experiment focused on determining where boundary-layer transition occurs on the glove and on identifying the flow mechanism causing transition over the glove. Data from this flight-research effort included temperature, heat transfer, pressure measurements, airflow, and trajectory reconstruction. Hypersonic flight-research programs are an approach to validate design methods for hypersonic vehicles (those that fly more than five times the speed of sound, or Mach 5). Dryden Flight Research Center, Edwards, California, provided overall management of the glove experiment, glove design, and buildup. Dryden also was responsible for conducting the flight tests. Langley Research Center, Hampton, Virginia, was responsible for the design of the aerodynamic glove as well as development of sensor and instrumentation systems for the glove. Other participating NASA centers included Ames Research Center, Mountain View, California; Goddard Space Flight Center, Greenbelt, Maryland; and Kennedy Space Center, Florida. Orbital Sciences Corporation, Dulles, Virginia, is the manufacturer of the Pegasus vehicle, while

  4. Nutritional vitamin B12 deficiency in a breast-fed infant of a vegan-diet mother.

    PubMed

    Sklar, R

    1986-04-01

    A 7-month-old male presented with lethargy and failure to thrive. The child was exclusively breast-fed from birth by a mother who was a strict vegetarian. Laboratory data revealed macrocytic anemia and methylmalonic acid in the urine, consistent with vitamin B12 deficient anemia. The patient responded well to supplementation with B12 alone and was developmentally normal by 11 months of age. This study emphasizes the need for assuring maternal dietary adequacy during pregnancy and after birth.

  5. Radiated noise characteristics of a modern cargo ship

    PubMed

    Arveson; Vendittis

    2000-01-01

    Extensive measurements were made of the radiated noise of M/V OVERSEAS HARRIETTE, a bulk cargo ship (length 173 m, displacement 25 515 tons) powered by a direct-drive low-speed diesel engine-a design representative of many modern merchant ships. The radiated noise data show high-level tonal frequencies from the ship's service diesel generator, main engine firing rate, and blade rate harmonics due to propeller cavitation. Radiated noise directionality measurements indicate that the radiation is generally dipole in form at lower frequencies, as expected. There are some departures from this pattern that may indicate hull interactions. Blade rate source level (174 dB re 1 microPa/m at 9 Hz, 16 knots) agrees reasonably well with a model of fundamental blade rate radiation previously reported by Gray and Greeley, but agreement for blade rate harmonics is not as good. Noise from merchant ships elevates the natural ambient by 20-30 dB in many areas; the effects of this noise on the biological environment have not been widely investigated.

  6. 46 CFR 98.30-14 - Requirements for ships carrying NLSs in portable tanks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... portable tank shall ensure that— (1) The ship's Certificate of Inspection is endorsed with the name of the... condition for endorsement is met. (b) To have a ship's Certificate of Inspection endorsed to allow the... 46 Shipping 4 2010-10-01 2010-10-01 false Requirements for ships carrying NLSs in portable tanks...

  7. Designing a lifestyle intervention to reduce risk of type 2 diabetes in postpartum mothers following gestational diabetes: An online survey with mothers and health professionals.

    PubMed

    Moore, Amanda P; D'Amico, Maria I; Cooper, Natalie A M; Thangaratinam, Shakila

    2018-01-01

    The aim of this study was to identify what components of a postpartum lifestyle intervention would engage postpartum mothers who had a diagnosis of gestational diabetes. Two online surveys were conducted, one involving postnatal mothers with GDM (n=83), and a second for health professionals (n=46). Seventy-eight percent of mothers were aware that healthy eating, exercise and weight management were all important to reduce risk of subsequent type 2 diabetes. However, 80% of women in this survey were not ready to engage in a postpartum lifestyle intervention within the first 6 months of giving birth; in contrast 52% of health professionals recommended they should be engaged in the first six weeks. Group sessions were the most commonly chosen format to deliver an intervention (30%). A community setting was preferred to a medical one. Mothers wanted recipe ideas (95%) in preference to general dietary advice (76%) or cooking skills courses (39%). Walking was the main form of exercise for 79% of mothers in this sample. Women highlighted difficulty in focusing on their own health goals because of competing demands of looking after a baby (41% agreed, Median 3, IQR 2), tiredness (65% agreed, Md 4, IQR 1) and the need for childcare (64% agreed, Md 4, IQR 2). A walking programme, recipe ideas and weight monitoring may be useful components when designing a postpartum lifestyle intervention. Barriers to engagement are evident and the intervention should allow women to engage at a time that is appropriate for them. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Are nuclear ships environmentally safer than conventionally powered ships

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bone, C.A.; Molgaard, C.A.; Helmkamp, J.C.

    1988-03-01

    An epidemiologic analysis was conducted to determine if risk of hospitalization varied by age, ship type, or occupation between nuclear and conventional powered ship crews in the U.S. Navy. Study cohorts consisted of all male enlisted personnel who served exclusively aboard conventional or nuclear powered aircraft carriers and cruisers during the years 1975-1979; cases were those men hospitalized during this period (N = 48,242). Conventional ship personnel showed significantly elevated rates of injury and disease when compared to nuclear ship personnel. The largest relative risks by age occurred for conventional ship crewmen less than 30 years old. Seaman, logistics (supply),more » and healthcare personnel serving aboard conventional ships comprised the occupational groups exhibiting the highest hospitalization rate differentials. The results strongly suggest that nuclear ships provide a healthier, safer working and living environment than conventional ships.« less

  9. 52. G.E.H. photographer August 1930 1HUM1B #59, OILING OPERATIONS, GEH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. G.E.H. photographer August 1930 1-HUM-1-B #59, OILING OPERATIONS, GEH 8-30. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  10. An infant and mother with severe B12 deficiency: vitamin B12 status assessment should be determined in pregnant women with anaemia.

    PubMed

    Sobczyńska-Malefora, A; Ramachandran, R; Cregeen, D; Green, E; Bennett, P; Harrington, D J; Lemonde, H A

    2017-08-01

    The vitamin B 12 status of infants depends on maternal B 12 status during pregnancy, and during lactation if breastfed. We present a 9-month-old girl who was admitted to the metabolic unit for assessment of developmental delay. She was exclusively breastfed and the introduction of solids at 5 months was unsuccessful. Investigations revealed pancytopenia, undetectable B 12 and highly elevated methylmalonic acid and homocysteine. Methylmalonic acid and homocysteine normalised following B 12 injections. Marked catch-up of developmental milestones was noted after treatment with B 12 . Investigations of parents showed normal B 12 in the father and combined B 12 and iron deficiency in the mother. Maternal B 12 deficiency, most likely masked by iron deficiency, led to severe B 12 deficiency in the infant. Exclusive breastfeeding and a subsequent failure to wean exacerbated the infant's B 12 deficiency leading to developmental delay. This case highlights the need for development of guidelines for better assessment of B 12 status during pregnancy.

  11. Review of ship slamming loads and responses

    NASA Astrophysics Data System (ADS)

    Wang, Shan; Guedes Soares, C.

    2017-12-01

    The paper presents an overview of studies of slamming on ship structures. This work focuses on the hull slamming, which is one of the most important types of slamming problems to be considered in the ship design process and the assessment of the ship safety. There are three main research aspects related to the hull slamming phenomenon, a) where and how often a slamming event occurs, b) slamming load prediction and c) structural response due to slamming loads. The approaches used in each aspect are reviewed and commented, together with the presentation of some typical results. The methodology, which combines the seakeeping analysis and slamming load prediction, is discussed for the global analysis of the hull slamming of a ship in waves. Some physical phenomena during the slamming event are discussed also. Recommendations for the future research and developments are made.

  12. Hepatitis B virus infections in families in which the mothers are negative but the fathers are positive for HBsAg.

    PubMed

    Takegoshi, Kunio; Zhang, Wei

    2006-10-01

    We studied a total of 37 families, in which HBsAg was positive in either or both of father and mother, to assess intra-familial transmission of hepatitis B virus (HBV). The HBsAg positive rate for children with HBsAg-negative mothers was significantly lower than that with positive mothers (4 of 31, 12.9% versus 18 of 32, 56.3%, p<0.01) of course. However, there were three families in which the infection source for children was thought to be fathers, not mothers, i.e., of eight children in these three families with HBsAg +/- father/mother pairs, 4 (50%) were positive for both HBsAg and HBV DNA of genotypes identical to those of their fathers, and another child was positive for HBcAb despite being negative for HBsAg. Interestingly, moreover, all the mothers in these three families were HBcAb-positive even though HBsAg-negative, suggesting that not only father-to-child but also inter-spouse HBV transmission might have occurred. With these findings we would suggest that all the family members with HBsAg-positive fathers should receive HBV vaccine, let alone for those with HBsAg-positive mothers.

  13. 46 CFR 160.133-19 - Operating instructions and information for the ship's training manual.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Operating instructions and information for the ship's... ship's training manual. (a) Each release mechanism must have instructions and information for the ship....133-5 of this subpart) to describe the location and operation of the release mechanism. (b) The...

  14. 46 CFR 160.133-19 - Operating instructions and information for the ship's training manual.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Operating instructions and information for the ship's... ship's training manual. (a) Each release mechanism must have instructions and information for the ship....133-5 of this subpart) to describe the location and operation of the release mechanism. (b) The...

  15. Electrolyte profile of Malaysian mothers' milk.

    PubMed

    Alaudeen, S; Muslim, N; Faridah, K; Azman, A; Arshat, H

    1988-12-01

    The influence of socioeconomic status (ethnicity, income and parity) on electrolyte composition (sodium and potassium) in human milk is little known. We have thus quantitatively analyzed approximately 700 samples of milk (1-90 days postpartum) obtained from healthy Malaysian mothers' (Malay, Chinese and Indians) of full term infants. Results show that the mean concentration (mmol/l) of sodium is highest (48.2+or-1.7, Mean+or-SEM) in the Malaysian mothers' colostrum and this value decreased by 30% in their transitional milk and remained constant throughout subsequent days of lactation (mature milk). Ethnically, it is found that the level of sodium in colostrum of Malay and Chinese mothers were similar while the Indian mothers' colostrum showed apparently higher value (52.7+or-3.4 mmol/l) that is statistically insignificant. The transitional milk of all 3 ethnic groups studied exhibited similar levels of sodium. On subsequent days of lactation (mature milk) the Malay mothers exhibited lowest concentration (25.9+or-2.6 mmol/l) of sodium that is significantly (P0.05) different from that of Chinese and Indian mothers. Income and parity do not significantly affect the sodium level in Malaysian mothers' milk during all stages of lactation studied. The level of potassium, however did not change significantly with days of lactation. Like sodium, potassium too was not influenced by income and parity. (Author's).

  16. Electrolyte profile of Malaysian mothers' milk.

    PubMed

    Shaikh Alaudeen; Nor Muslim; Kamarul Faridah; Ali Azman; Hamid Arshat

    1988-12-01

    The influence of socioeconomic status (ethnicity, income, and parity) on electrolyte composition (sodium and potassium) in human milk is little known. The authors have thus quantitatively analyzed approximately 700 samples of milk (1-90 days postpartum) obtained from healthy Malaysian mothers (Malay, Chinese, and Indians) of full-term infants. Results show that the mean concentration (mmol/1) of sodium is highest 48.2 +/- 1.7; mean +/- SEM) in the Malaysian mothers' colostrum and this value decreased by 30% in their transitional milk and remained constant throughout subsequent days of lactation. Ethnically, it is found that the level of sodium in colostrum of Malay and Chinese mothers was similar but the Indian mothers' colostrum showed apparently higher value (52.7 +/- 3.4 mmpl/1) that is statistically insignificant. The transitional milk of all 3 ethnic groups studied exhibited similar levels of sodium. On subsequent days of lactation (mature milk) the Malay mothers exhibited the lowest concentration (25.9 +/- 2.6 mmol/1) of sodium that is significantly (p .05) different from that of Chinese and Indian mothers. Income and parity do not significantly affect the sodium level in Malaysian mothers' milk during all stages of lactation studied. The level of potassium, however, did not change significantly with days of lactation. Like sodium, potassium too was not influenced by income and parity.

  17. Macrophage Pro-Inflammatory Response to Francisella novicida Infection Is Regulated by SHIP

    PubMed Central

    Parsa, Kishore V. L; Ganesan, Latha P; Rajaram, Murugesan V. S; Gavrilin, Mikhail A; Balagopal, Ashwin; Mohapatra, Nrusingh P; Wewers, Mark D; Schlesinger, Larry S; Gunn, John S; Tridandapani, Susheela

    2006-01-01

    Francisella tularensis, a Gram-negative facultative intracellular pathogen infecting principally macrophages and monocytes, is the etiological agent of tularemia. Macrophage responses to F. tularensis infection include the production of pro-inflammatory cytokines such as interleukin (IL)-12, which is critical for immunity against infection. Molecular mechanisms regulating production of these inflammatory mediators are poorly understood. Herein we report that the SH2 domain-containing inositol phosphatase (SHIP) is phosphorylated upon infection of primary murine macrophages with the genetically related F. novicida, and negatively regulates F. novicida–induced cytokine production. Analyses of the molecular details revealed that in addition to activating the MAP kinases, F. novicida infection also activated the phosphatidylinositol 3-kinase (PI3K)/Akt pathway in these cells. Interestingly, SHIP-deficient macrophages displayed enhanced Akt activation upon F. novicida infection, suggesting elevated PI3K-dependent activation pathways in absence of SHIP. Inhibition of PI3K/Akt resulted in suppression of F. novicida–induced cytokine production through the inhibition of NFκB. Consistently, macrophages lacking SHIP displayed enhanced NFκB-driven gene transcription, whereas overexpression of SHIP led to decreased NFκB activation. Thus, we propose that SHIP negatively regulates F. novicida–induced inflammatory cytokine response by antagonizing the PI3K/Akt pathway and suppressing NFκB-mediated gene transcription. A detailed analysis of phosphoinositide signaling may provide valuable clues for better understanding the pathogenesis of tularemia. PMID:16848641

  18. Does oxytocin modulate variation in maternal caregiving in healthy new mothers?

    PubMed

    Elmadih, Alya; Wan, Ming Wai; Numan, Michael; Elliott, Rebecca; Downey, Darragh; Abel, Kathryn M

    2014-09-11

    Maternal sensitivity to infant cues and developmental needs may be pivotal for social and cognitive development. Animal and recent human studies emphasise a major role for Oxytocin (OT) in mediating sensitive caregiving but no study has examined the relationship between OT and extreme variation in human maternal sensitivity. From 105 expectant mothers, 80 underwent blind-rating of maternal sensitivity at 4-6 months postpartum through free-play interaction with their infants. At 7-9 months postpartum, 30 mothers at extremes of maternal sensitivity: 15 'sensitive mothers' (high sensitivity mothers - HSMs, mean=4.47; SD=0.74) and 15 'less sensitive mothers' (low sensitivity mothers - LSMs, mean=2.13; SD=0.52) underwent plasma OT measurements before and after 10 min infant play. Baseline and post-interaction plasma OT was higher in LSMs than HSMs [F(1, 26)=8.42; p=0.01]. HSMs showed a trend towards significant reduction in plasma OT [t(14)=2.01; p=0.06] following play-interaction; no change was shown by LSMs [t(13)=-0.14; p=0.89]. Conclusion Higher baseline OT levels in healthy LSMs may imply greater stress responses to the demands of caring for an infant, or past deficiencies in own parenting relationship and act as a biomarker for poor parental sensitivity. OT may be acting to reduce stress and anxiety in LSMs consistent with studies of plasma OT and stress in women. By contrast, in HSMs, play interaction with their infants maybe relaxing as indicated by significant reduction in plasma OT from baseline. Ascertainment of mothers in well-defined sensitivity groups might facilitate examination of distinct coping strategies in parents and better understanding of variation in parental caregiving behaviour and its potential for modulation by OT. This article is part of a Special Issue entitled Oxytocin and Social Behav. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. NASA's B-52B launch aircraft cruises to a test range over the Pacific Ocean carrying the third X-43A vehicle attached to a Pegasus rocket on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft, attached to a modified Pegasus booster rocket, was taken to launch altitude by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was released from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

  20. Fireproof impact limiter aggregate packaging inside shipping containers

    DOEpatents

    Byington, Gerald A.; Oakes, Jr., Raymon Edgar; Feldman, Matthew Rookes

    2001-01-01

    The invention is a product and a process for making a fireproof, impact limiter, homogeneous aggregate material for casting inside a hazardous material shipping container, or a double-contained Type-B nuclear shipping container. The homogeneous aggregate material is prepared by mixing inorganic compounds with water, pouring the mixture into the void spaces between an inner storage containment vessel and an outer shipping container, vibrating the mixture inside the shipping container, with subsequent curing, baking, and cooling of the mixture to form a solidified material which encapsulates an inner storage containment vessel inside an outer shipping container. The solidified material forms a protective enclosure around an inner storage containment vessel which may store hazardous, toxic, or radioactive material. The solidified material forms a homogeneous fire-resistant material that does not readily transfer heat, and provides general shock and specific point-impact protection, providing protection to the interior storage containment vessel. The material is low cost, may contain neutron absorbing compounds, and is easily formed into a variety of shapes to fill the interior void spaces of shipping containers.

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