Sample records for b52 antifoam impact

  1. Illinois Institute of Technology Report: IITB52 Antifoamer for Alternative Salt Processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lambert, D.P.

    2001-06-27

    The attached report is a summary of the work performed by Dr. Darsh Wasan, Dr. Alex Nikolov, and their researchers at the Illinois Institute of Technology (IIT) during FY01. IIT developed the IITB52 antifoam for SRTC in FY00 to minimize the foam produced during precipitation, washing and concentration of cesium and potassium tetraphenyl borate precipitate. The IITB52 antifoam has been very successful during continuous processing (prototypical of plant operation). However, there were several key issues where SRTC needed the experience and knowledge of IIT to resolve. As a result a subcontract was set up with Dr. Wasan and Dr. Alexmore » Nikolov during FY01. This subcontract requested IIT to perform the basic research necessary to understand the foaming mechanism and explain the effectiveness of the IITB52 antifoam agent in the Small Tank Tetraphenylborate Process (STTP).« less

  2. Impact of Colloidal Silica on Silicone Oil-Silica Mixed Antifoams

    NASA Astrophysics Data System (ADS)

    Yuan, Zheng

    Antifoams are utilized as an industrial additive to control undesired foam during processing. This study focuses on the impact of silica on the antifoam stability. Antifoam stability refers to the ability to maintain efficiency in foam destruction after prolonged shelf storage. Common antifoams are a mixture of hydrophobic silica particles and silicone oil. Based on the general mechanisms of antifoam action discussed in Chapter 1, silica particles play a significant role in foam destruction. Silica particles contribute to foam control by facilitating the entry and the penetration depth of oil-silica globules into surfactant-water films (foam bubble walls). The size, morphology and hydrophobicity of silica can be manipulated to generate optimal antifoam globules. For example, the two silicas with good shelf life performance (8375 and 9512) had the largest silica particles and both showed a tendency to aggregate in toluene solution. We conclude that improved shelf life is related to the propensity of PDMS oil to adsorb on silica, which leads to aggregation and particle size increase. We measured the time-evolution of dynamic light scattering (DLS) from 3-vol% antifoam dissolved in toluene (Chapter 2). For the sample with the largest hydrodynamic radius (9512) the scattered intensity decreased significantly after applying ultrasonic dispersion. Decreasing intensity also occurred for 8375 albeit at later times. The decrease of intensity is attributed to the growth and precipitation of oil-silica globules. The concentration dependence of light scattering confirmed the growth-precipitation hypothesis. FT-IR (Chapter 3) was consistent with precipitation due to oil adsorption, but the data were not definitive. Chapter 4 examines the time-evolution of silica structures by static light scattering and X-ray scattering. The combined data are consistent with a hierarchical structure for silica. Agglomeration occurred fastest for 9512, which is consistent with DLS observations

  3. Foams and antifoams.

    PubMed

    Karakashev, Stoyan I; Grozdanova, Michaela V

    2012-01-01

    harnessed both the most successful type of FTT and the interferometric thin film setup of Scheludko to conduct innovative experiments on the antifoam's action in the foam films under different conditions. They derived new more detailed understanding on the antifoam's action. For this reason, we must acknowledge the series of works under the supervision of N. Denkov performed between 1996 and 2004 as the lately ones in the field. The present work contains in addition a subchapter devoted to describing alternative methods for design and control of the foam stability. As far as the foaminess and the rate of foam decay depends on the states of the surfactant adsorption layers situated on the bubble surfaces, both foaminess and foam durability can be designed by means of proper choices of surfactants, concentrations and methods of foam generation. Therefore, this paper scrutinized the very mechanism of foam generation whose product is initial foam. Afterwards it was pointed out that the elastic modulus of the foam bubbles is responsible for the further "life" of the already generated foam. A compilation between foaminess and average rate of foam decay named foam production was shown as more successful way to describe the foaming capacity of the frothers. In addition, the properties of tenacious famous under various conditions were exhibited as well. This subchapter does not give any formula for precise design of foams with entailed durability but rather outlines new ways to achieve such recipe. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Antifoam degradation testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lambert, D. P.; Zamecnik, J. R.; Newell, D. D.

    2015-08-20

    This report describes the results of testing to quantify the degradation products resulting from the dilution and storage of Antifoam 747. Antifoam degradation is of concern to the Defense Waste Processing Facility (DWPF) due to flammable decomposition products in the vapor phase of the Chemical Process Cell vessels, as well as the collection of flammable and organic species in the offgas condensate. The discovery that hexamethyldisiloxane is formed from the antifoam decomposition was the basis for a Potential Inadequacy in the Safety Analysis declaration by the DWPF.

  5. Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro‐bioreactor system

    PubMed Central

    Velugula‐Yellela, Sai Rashmika; Williams, Abasha; Trunfio, Nicholas; Hsu, Chih‐Jung; Chavez, Brittany; Yoon, Seongkyu

    2017-01-01

    Monoclonal antibody production in commercial scale cell culture bioprocessing requires a thorough understanding of the engineering process and components used throughout manufacturing. It is important to identify high impact components early on during the lifecycle of a biotechnology‐derived product. While cell culture media selection is of obvious importance to the health and productivity of mammalian bioreactor operations, other components such as antifoam selection can also play an important role in bioreactor cell culture. Silicone polymer‐based antifoams were known to have negative impacts on cell health, production, and downstream filtration and purification operations. High throughput screening in micro‐scale bioreactors provides an efficient strategy to identify initial operating parameters. Here, we utilized a micro‐scale parallel bioreactor system to study an IgG1 producing CHO cell line, to screen Dynamis, ProCHO5, PowerCHO2, EX‐Cell Advanced, and OptiCHO media, and 204, C, EX‐Cell, SE‐15, and Y‐30 antifoams and their impacts on IgG1 production, cell growth, aggregation, and process control. This study found ProCHO5, EX‐Cell Advanced, and PowerCHO2 media supported strong cellular growth profiles, with an IVCD of 25‐35 × 106 cells‐d/mL, while maintaining specific antibody production (Qp > 2 pg/cell‐d) for our model cell line and a monomer percentage above 94%. Antifoams C, EX‐Cell, and SE‐15 were capable of providing adequate control of foaming while antifoam 204 and Y‐30 noticeably stunted cellular growth. This work highlights the utility of high throughput micro bioreactors and the importance of identifying both positive and negative impacts of media and antifoam selection on a model IgG1 producing CHO cell line. © 2017 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. on behalf of American Institute of Chemical Engineers Biotechnol. Prog., 34:262–270, 2018 PMID:29086492

  6. The Effects of Antifoam Agent on Dead End Filtration Process

    NASA Astrophysics Data System (ADS)

    Mohamad Pauzi, S.; Ahmad, N.; Yahya, M. F.; Arifin, M. A.

    2018-05-01

    The formation of foam as a result from introducing gases during cell culture process in the bioprocess industry has indirectly affected the throughput of the product of interest. Due to that, antifoams were developed and established as one of the means to minimize the formation of foam in the cell culture. There are many types of antifoams but the silicone-type of antifoams are widely used in the bioprocess industry. Although the establishment of antifoam has aided the cell culture process, the impacts of its presence in the cell culture to the downstream process especially the dead end filtration is not widely discussed. The findings in the study emphasized on the dead end filtration performance that includes flux rate profile and the resulted filtration capacity. In this study, the concentrations of antifoam injected into the solution were varied from 0.2% v/v – 1.0% v/v and the solutions were filtered using constant flow method. The resulted maximum pressure readings and final flux rates indicated that the resistance exerted to the feed flow rate increased as the concentration of antifoam loaded in the solution increased. This later has led to the decline in the flux rates with percentage reduction between 32 – 68%. The calculated filter capacity for flux rate of 1000LMH ranged from 53 – 63L/m2 while it is in the range of 40 – 43L/m2 for flux rate of 2000LMH. The presence of antifoam agents in the feed load was determined to have negative effects on the dead end filtration performance and it may reduce the efficiency of the dead end filtration process.

  7. IMPROVED ANTIFOAM AGENT STUDY END OF YEAR REPORT, EM PROJECT 3.2.3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lambert, D.; Koopman, D.; Newell, J.

    2011-09-30

    Antifoam 747 is added to minimize foam produced by process gases and water vapor during chemical processing of sludge in the Defense Waste Processing Facility (DWPF). This allows DWPF to maximize acid addition and evaporation rates to minimize the cycle time in the Chemical Processing Cell (CPC). Improvements in DWPF melt rate due to the addition of bubblers in the melter have resulted in the need for further reductions in cycle time in the CPC. This can only be accomplished with an effective antifoam agent. DWPF production was suspended on March 22, 2011 as the result of a Flammable Gasmore » New Information/(NI) Potential Inadequacy in the Safety Analysis (PISA). The issue was that the DWPF melter offgas flammability strategy did not take into account the H and C in the antifoam, potentially flammable components, in the melter feed. It was also determined the DWPF was using much more antifoam than anticipated due to a combination of longer processing in the CPC due to high Hg, longer processing due to Actinide Removal Process (ARP)/Modular Caustic Side Solvent Extraction Unit (MCU) additions, and adding more antifoam than recommended. The resolution to the PISA involved and assessment of the impact of the antifoam on melter flammability and the implementation of a strategy to control additions within acceptable levels. This led to the need to minimize the use of Antifoam 747 in processing beginning in May 2011. DWPF has had limited success in using Antifoam 747 in caustic processing. Since starting up the ARP facility, the ARP product (similar chemically to caustic sludge) is added to the Sludge Receipt and Adjustment Tank (SRAT) at boiling and evaporated to maintain a constant SRAT volume. Although there is very little offgas generated during caustic boiling, there is a large volume of water vapor produced which can lead to foaming. High additions and more frequent use of antifoam are used to mitigate the foaming during caustic boiling. The result of these

  8. Effects of anti-foaming agents on biohydrogen production.

    PubMed

    Sivagurunathan, Periyasamy; Anburajan, Parthiban; Kumar, Gopalakrishnan; Bakonyi, Péter; Nemestóthy, Nándor; Bélafi-Bakó, Katalin; Kim, Sang-Hyoun

    2016-08-01

    The effects of antifoaming agents on fermentative hydrogen production using galactose in batch and continuous operations were investigated. Batch hydrogen production assays with LS-303 (dimethylpolysiloxane), LG-109 (polyalkylene), LG-126 (polyoxyethylenealkylene), and LG-299 (polyether) showed that the doses and types of antifoaming agents played a significant role in hydrogen production. During batch tests, LS-303 at 100μL/L resulted in the maximum hydrogen production rate (HPR) and hydrogen yield (HY) of 2.5L/L-d and 1.08mol H2/mol galactoseadded, respectively. The following continuously stirred tank reactor operated at 12h HRT with LS-303 at 100μL/L showed a stable HPR and HY of 4.9L/L-d and 1.17mol H2/mol galactoseadded, respectively, which were higher than those found for the control reactor. Microbial community analysis supported the alterations in H2 generation under different operating conditions and the stimulatory impact of certain antifoaming chemicals on H2 production was demonstrated. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Antifoam addition to shake flask cultures of recombinant Pichia pastoris increases yield

    PubMed Central

    2011-01-01

    Background Pichia pastoris is a widely-used host for recombinant protein production. Initial screening for both suitable clones and optimum culture conditions is typically carried out in multi-well plates. This is followed by up-scaling either to shake-flasks or continuously stirred tank bioreactors. A particular problem in these formats is foaming, which is commonly prevented by the addition of chemical antifoaming agents. Intriguingly, antifoams are often added without prior consideration of their effect on the yeast cells, the protein product or the influence on downstream processes such as protein purification. In this study we characterised, for the first time, the effects of five commonly-used antifoaming agents on the total amount of recombinant green fluorescent protein (GFP) secreted from shake-flask cultures of this industrially-relevant yeast. Results Addition of defined concentrations of Antifoam A (Sigma), Antifoam C (Sigma), J673A (Struktol), P2000 (Fluka) or SB2121 (Struktol) to shake-flask cultures of P. pastoris increased the total amount of recombinant GFP in the culture medium (the total yield) and in the case of P2000, SB2121 and J673A almost doubled it. When normalized to the culture density, the GFP specific yield (μg OD595-1) was only increased for Antifoam A, Antifoam C and J673A. Whilst none of the antifoams affected the growth rate of the cells, addition of P2000 or SB2121 was found to increase culture density. There was no correlation between total yield, specific yield or specific growth rate and the volumetric oxygen mass transfer coefficient (kLa) in the presence of antifoam. Moreover, the antifoams did not affect the dissolved oxygen concentration of the cultures. A comparison of the amount of GFP retained in the cell by flow cytometry with that in the culture medium by fluorimetry suggested that addition of Antifoam A, Antifoam C or J673A increased the specific yield of GFP by increasing the proportion secreted into the medium

  10. Organics Characterization Of DWPF Alternative Reductant Simulants, Glycolic Acid, And Antifoam 747

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White, T. L.; Wiedenman, B. J.; Lambert, D. P.

    amounts of impurities such as formic and diglycolic acid that were then carried over in the SME products. Oxalic acid present in the simulated tank farm waste was also detected. Finally, numerous other compounds, at low concentrations, were observed present in etheric extracts of aqueous supernate solutions of the SME samples and are thought to be breakdown products of antifoam 747. The data collectively suggest that although addition of glycolic acid and antifoam 747 will introduce a number of impurities and breakdown products into the melter feed, the concentrations of these organics is expected to remain low and may not significantly impact REDOX or off-gas flammability predictions. In the SME products examined presently, which contained variant amounts of glycolic acid and antifoam 747, no unexpected organic degradation product was found at concentrations above 500 mg/kg, a reasonable threshold concentration for an organic compound to be taken into account in the REDOX modeling. This statement does not include oxalic or formic acid that were sometimes observed above 500 mg/kg and acetic acid that has an analytical detection limit of 1250 mg/kg due to high glycolate concentration in the SME products tested. Once a finalized REDOX equation has been developed and implemented, REDOX properties of known organic species will be determined and their impact assessed. Although no immediate concerns arose during the study in terms of a negative impact of organics present in SME products of the glycolic flowsheet, evidence of antifoam degradation suggest that an alternative antifoam to antifoam 747 is worth considering. The determination and implementation of an antifoam that is more hydrolysis resistant would have benefits such as increasing its effectiveness over time and reducing the generation of degradation products.« less

  11. Antifoaming effect of chemical compounds in manure biogas reactors.

    PubMed

    Kougias, P G; Tsapekos, P; Boe, K; Angelidaki, I

    2013-10-15

    A precise and efficient antifoaming control strategy in bioprocesses is a challenging task as foaming is a very complex phenomenon. Nevertheless, foam control is necessary, as foam is a major operational problem in biogas reactors. In the present study, the effect of 14 chemical compounds on foam reduction was evaluated at concentration of 0.05%, 0.1% and 0.5% v/v(sample), in raw and digested manure. Moreover, two antifoam injection methods were compared for foam reduction efficiency. Natural oils (rapeseed and sunflower oil), fatty acids (oleic, octanoic and derivative of natural fatty acids), siloxanes (polydimethylsiloxane) and ester (tributylphosphate) were found to be the most efficient compounds to suppress foam. The efficiency of antifoamers was dependant on their physicochemical properties and greatly correlated to their chemical characteristics for dissolving foam. The antifoamers were more efficient in reducing foam when added directly into the liquid phase rather than added in the headspace of the reactor. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. DEVELOPMENT OF AN ANTIFOAM TRACKING SYSTEM AS AN OPTION TO SUPPORT THE MELTER OFF-GAS FLAMMABILITY CONTROL STRATEGY AT THE DWPF

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, T.; Lambert, D.

    The Savannah River National Laboratory (SRNL) has been working with the Savannah River Remediation (SRR) Defense Waste Processing Facility (DWPF) in the development and implementation of an additional strategy for confidently satisfying the flammability controls for DWPF’s melter operation. An initial strategy for implementing the operational constraints associated with flammability control in DWPF was based upon an analytically determined carbon concentration from antifoam. Due to the conservative error structure associated with the analytical approach, its implementation has significantly reduced the operating window for processing and has led to recurrent Slurry Mix Evaporator (SME) and Melter Feed Tank (MFT) remediation. Tomore » address the adverse operating impact of the current implementation strategy, SRR issued a Technical Task Request (TTR) to SRNL requesting the development and documentation of an alternate strategy for evaluating the carbon contribution from antifoam. The proposed strategy presented in this report was developed under the guidance of a Task Technical and Quality Assurance Plan (TTQAP) and involves calculating the carbon concentration from antifoam based upon the actual mass of antifoam added to the process assuming 100% retention. The mass of antifoam in the Additive Mix Feed Tank (AMFT), in the Sludge Receipt and Adjustment Tank (SRAT), and in the SME is tracked by mass balance as part of this strategy. As these quantities are monitored, the random and bias uncertainties affecting their values are also maintained and accounted for. This report documents: 1) the development of an alternate implementation strategy and associated equations describing the carbon concentration from antifoam in each SME batch derived from the actual amount of antifoam introduced into the AMFT, SRAT, and SME during the processing of the batch. 2) the equations and error structure for incorporating the proposed strategy into melter off-gas flammability

  13. Evaluation of thiolated silicone oil as advanced mucoadhesive antifoaming agent.

    PubMed

    Partenhauser, Alexandra; Netsomboon, Kesinee; Leonaviciute, Gintare; Bernkop-Schnürch, Andreas

    2016-10-01

    Silicone oils, such as dimethicone, are commonly administered against gastrointestinal gas accumulation and are attributed with mucoprotective features. Evaluation of thiolated silicone oil as advanced antiflatulence with a prolonged retention on small intestinal mucosa as an intended site of action. 3-Mercaptopropionic acid (MPA) as a thiol ligand was covalently attached to silicone oil. This thiomer was assessed with regard to foam inhibiting action, droplet size of a suitable self-emulsifying system, mucoadhesion and cytotoxicity. Antifoaming activity of silicone-MPA was complying with United States Pharmacopeia (USP) requirements for simethicone as standard antiflatulence. Another antifoaming test performed on porcine mucosa supported silicone-MPA's outstanding foam destruction, as this thiomer was superior in comparison to non-thiolated silicone oil and dimethicone with 14.7 ± 2.1 versus 73.3 ± 9.1 and 66.3 ± 7.5 s, respectively. A significantly enhanced mucoadhesiveness (p < 0.02) with 26.2 ± 7.1% silicone formulation remaining on small intestinal mucosa after 8 h was evident for the thiomer without any toxic effect. Thiolated silicone oil was found to exhibit excellent antifoaming and superior mucoadhesive features. The prolonged residence time of thiolated silicone oil promises to be beneficial in the treatment of flatulence, aerophagy and inflammation throughout the whole gastrointestinal tract.

  14. Characterisation of HFBII biosurfactant production and foam fractionation with and without antifoaming agents.

    PubMed

    Winterburn, James B; Russell, Andrew B; Martin, Peter J

    2011-05-01

    The effects of foaming on the production of the hydrophobin protein HFBII by fermentation have been investigated at two different scales. The foaming behaviour was characterised in standard terms of the product enrichment and recovery achieved. Additional specific attention was given to the rate at which foam, product and biomass overflowed from the fermentation system in order to assess the utility of foam fractionation for HFBII recovery. HFBII was expressed as an extracellular product during fed-batch fermentations with a genetically modified strain of Saccharomyces cerevisiae, which were carried out with and without the antifoam Struktol J647. In the presence of antifoam, HFBII production is shown to be largely unaffected by process scale, with similar yields of HFBII on dry matter obtained. More variation in HFBII yield was observed between fermentations without antifoam. In fermentations without antifoam, a maximum HFBII enrichment in the foam phase of 94.7 was measured with an overall enrichment, averaged over all overflowed material throughout the whole fermentation, of 54.6 at a recovery of 98.1%, leaving a residual HFBII concentration of 5.3 mg L(-1) in the fermenter. It is also shown that uncontrolled foaming resulted in reduced concentration of biomass in the fermenter vessel, affecting total production. This study illustrates the potential of foam fractionation for efficient recovery of HFBII through simultaneous high enrichment and recovery which are greater than those reported for similar systems.

  15. Stress Analysis of B-52B and B-52H Air-Launching Systems Failure-Critical Structural Components

    NASA Technical Reports Server (NTRS)

    Ko, William L.

    2005-01-01

    The operational life analysis of any airborne failure-critical structural component requires the stress-load equation, which relates the applied load to the maximum tangential tensile stress at the critical stress point. The failure-critical structural components identified are the B-52B Pegasus pylon adapter shackles, B-52B Pegasus pylon hooks, B-52H airplane pylon hooks, B-52H airplane front fittings, B-52H airplane rear pylon fitting, and the B-52H airplane pylon lower sway brace. Finite-element stress analysis was performed on the said structural components, and the critical stress point was located and the stress-load equation was established for each failure-critical structural component. The ultimate load, yield load, and proof load needed for operational life analysis were established for each failure-critical structural component.

  16. B-52B Cockpit Instrument Panel

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This photo shows a close-up view of the instrument panel in the cockpit of NASA's B-52 research aircraft. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the HiMAT, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster

  17. Antifoam Degradation Products in Off Gas and Condensate of Sludge Batch 9 Simulant Nitric-Formic Flowsheet Testing for the Defense Waste Processing Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, T.

    Ten chemical processing cell (CPC) experiments were performed using simulant to evaluate Sludge Batch 9 for sludge-only and coupled processing using the nitric-formic flowsheet in the Defense Waste Processing Facility (DWPF). Sludge Receipt and Adjustment Tank (SRAT) and Slurry Mix Evaporator (SME) cycles were performed on eight of the ten. The other two were SRAT cycles only. Samples of the condensate, sludge, and off gas were taken to monitor the chemistry of the CPC experiments. The Savannah River National Laboratory (SRNL) has previously shown antifoam decomposes to form flammable organic products, (hexamethyldisiloxane (HMDSO), trimethylsilanol (TMS), and propanal), that are presentmore » in the vapor phase and condensate of the CPC vessels. To minimize antifoam degradation product formation, a new antifoam addition strategy was implemented at SRNL and DWPF to add antifoam undiluted.« less

  18. Quantitative determination of dimethicone in commercial tablets and capsules by Fourier transform infrared spectroscopy and antifoaming activity test.

    PubMed

    Torrado, G; García-Arieta, A; de los Ríos, F; Menéndez, J C; Torrado, S

    1999-03-01

    Fourier transform infrared (FTIR) spectroscopy and antifoaming activity test have been employed for the quantitative analysis of dimethicone. Linearity, accuracy and precision are presented for both methods. These methods have been also used to compare different dimethicone-containing proprietary medicines. FTIR spectroscopy has shown to be adequate for quantitation of dimethicone in commercial tablets and capsules in order to comply with USP requirements. The antifoaming activity test is able to detect incompatibilities between dimethicone and other constituents. The presence of certain enzymes in some medicinal products increases the defoaming properties of these formulations.

  19. 42 CFR 52b.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Definitions. 52b.2 Section 52b.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.2 Definitions. As used in this part: Act means the Public Health Service Act, as...

  20. 42 CFR 52b.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Definitions. 52b.2 Section 52b.2 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.2 Definitions. As used in this part: Act means the Public Health Service Act, as...

  1. Counteracting foaming caused by lipids or proteins in biogas reactors using rapeseed oil or oleic acid as antifoaming agents.

    PubMed

    Kougias, P G; Boe, K; Einarsdottir, E S; Angelidaki, I

    2015-08-01

    Foaming is one of the major operational problems in biogas plants, and dealing with foaming incidents is still based on empirical practices. Various types of antifoams are used arbitrarily to combat foaming in biogas plants, but without any scientific support this action can lead to serious deterioration of the methanogenic process. Many commercial antifoams are derivatives of fatty acids or oils. However, it is well known that lipids can induce foaming in manure based biogas plants. This study aimed to elucidate the effect of rapeseed oil and oleic acid on foam reduction and process performance in biogas reactors fed with protein or lipid rich substrates. The results showed that both antifoams efficiently suppressed foaming. Moreover rapeseed oil resulted in stimulation of the biogas production. Finally, it was reckoned that the chemical structure of lipids, and more specifically their carboxylic ends, is responsible for their foam promoting or foam counteracting behaviour. Thus, it was concluded that the fatty acids and oils could suppress foaming, while salt of fatty acids could generate foam. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. B-52 Launch Aircraft in Flight

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA's venerable B-52 mothership is seen here photographed from a KC-135 Tanker aircraft. The X-43 adapter is visible attached to the right wing. The B-52, used for launching experimental aircraft and for other flight research projects, has been a familiar sight in the skies over Edwards for more than 40 years and is also both the oldest B-52 still flying and the aircraft with the lowest flight time of any B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported

  3. Analysis Of Condensate Samples In Support Of The Antifoam Degradation Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hay, M.; Martino, C.

    2016-01-12

    The degradation of Antifoam 747 to form flammable decomposition products has resulted in declaration of a Potential Inadequacy in the Safety Analysis (PISA) for the Defense Waste Processing Facility (DWPF). Savannah River National Laboratory (SRNL) testing with simulants showed that hexamethyldisiloxane (HMDSO), trimethylsilanol (TMS), and 1-propanal are formed in the offgas from the decomposition of the antifoam. A total of ten DWPF condensate samples from Batch 735 and 736 were analyzed by SRNL for three degradation products and additional analytes. All of the samples were analyzed to determine the concentrations of HMDSO, TMS, and propanal. The results of the organicmore » analysis found concentrations for propanal and HMDSO near or below the detection limits for the analysis. The TMS concentrations ranged from below detection to 11 mg/L. The samples from Batch 736 were also analyzed for formate and oxalate anions, total organic carbon, and aluminum, iron, manganese, and silicon. Most of the samples contained low levels of formate and therefore low levels of organic carbon. These two values for each sample show reasonable agreement in most cases. Low levels of all the metals (Al, Fe, Mn, and Si) were present in most of the samples.« less

  4. ANALYSIS OF CONDENSATE SAMPLES IN SUPPORT OF THE ANTIFOAM DEGRADATION STUDY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hay, M.; Martino, C.

    2016-02-29

    The degradation of Antifoam 747 to form flammable decomposition products has resulted in declaration of a Potential Inadequacy in the Safety Analysis (PISA) for the Defense Waste Processing Facility (DWPF). Savannah River National Laboratory (SRNL) testing with simulants showed that hexamethyldisiloxane (HMDSO), trimethylsilanol (TMS), and 1-propanal are formed in the offgas from the decomposition of the antifoam. A total of ten DWPF condensate samples from Batch 735 and 736 were analyzed by SRNL for three degradation products and additional analytes. All of the samples were analyzed to determine the concentrations of HMDSO, TMS, and propanal. The results of the organicmore » analysis found concentrations for propanal and HMDSO near or below the detection limits for the analysis. The TMS concentrations ranged from below detection to 11 mg/L. The samples from Batch 736 were also analyzed for formate and oxalate anions, total organic carbon, and aluminum, iron, manganese, and silicon. Most of the samples contained low levels of formate and therefore low levels of organic carbon. These two values for each sample show reasonable agreement in most cases. Low levels of all the metals (Al, Fe, Mn, and Si) were present in most of the samples.« less

  5. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  6. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  7. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  8. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  9. 42 CFR 52b.13 - Additional conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Additional conditions. 52b.13 Section 52b.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.13 Additional conditions. The Director may with respect to any grant...

  10. B-52G crew noise exposure study

    NASA Astrophysics Data System (ADS)

    Decker, W. H.; Nixon, C. W.

    1985-08-01

    The B-52G aircraft produces acoustic environments that are potentially hazardous, interfere with voice communications and may degrade task performance. Numerous reports from aircrew of high noise levels at crew location have been documented for those B-52G aircraft that have been modified with the Offensive Avionics System. To alleviate and minimize the excessive noise exposures of aircrews, a study of the noise problem in the b-52G was deemed necessary. First, in-flight noise measurements were obtained at key personnel locations on a B-52G during a typical training mission. Then, extensive laboratory analyses were conducted on these in-flight noise data. The resulting noise exposure data were evaluated in terms of the various segments of and the total flight profile relative to allowable noise exposures. Finally, recommendations were developed for short term and long term approaches toward potential improvement in the B-52G noise exposure problem.

  11. B-52 Testing F-111 Parachute

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A mock-up of an F-111 cockpit section drops out of the bomb bay of NASA's B-52 mothership on a test flight of a new parachute system for the F-111 'Aardvark' bomber. The F-111's ejection system separated the entire cockpit from the rest of the aircraft, and a large parachute was then deployed to lower the cockpit section to the ground. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  12. B-52 Testing F-111 Parachute

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The main parachute begins to deploy on the mock-up of an F-111 'Aardvark' bomber cockpit section after being dropped from NASA's B-52 mothership during 1988 flight tests on improved parachute systems for the Air Force bomber. The F-111's ejection system separated the entire cockpit from the rest of the aircraft, and a large parachute was then deployed to lower the cockpit section to the ground. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of

  13. B-52 Flight Mission Symbology - Close up

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A close-up view of some of the mission markings that tell the story of the NASA B-52 mothership's colorful history. These particular markings denote some of the experiments the bomber conducted to develop parachute recovery systems for the solid rocket boosters used by the Space Shuttle. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported

  14. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  15. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  16. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  17. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  18. 42 CFR 52b.4 - How to apply.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How to apply. 52b.4 Section 52b.4 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.4 How to apply. Applications for construction grants under this part shall be made at...

  19. The second X-43A hypersonic research vehicle, mounted under the right wing of the B-52B launch aircraft, viewed from the B-52 cockpit

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research vehicle, mounted under the right wing of the B-52B launch aircraft, viewed from the B-52 cockpit. The crew is working on closing out the research vehicle, preparing it for flight.

  20. Pegasus Mated to B-52 Mothership - Front View

    NASA Technical Reports Server (NTRS)

    1991-01-01

    NASA's B-52 launch aircraft takes off with the second Pegasus vehicle under its wing from the Dryden Flight Research Facility (now the Dryden Flight Research Center), Edwards, California. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In addition, the B-52 served as the air

  1. Dryden B-52 Launch Aircraft on Dryden Ramp

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable B-52 mothership sits on the ramp in front of the Dryden Flight Research Center, Edwards, California. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the X-38, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  2. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A close-up of an experimental drag chute deploying in a cloud of dust behind NASA's B-52 research aircraft just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover

  3. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    An aerial view of NASA's B-52 research aircraft deploying an experimental drag chute just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid

  4. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    NASA's B-52 research aircraft deploys an experimental drag chute just after landing the runway at the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also

  5. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    An experimental drag chute deploys amidst a cloud of dust behind NASA's B-52 research aircraft just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  6. B-52 Testing Developmental Space Shuttle Drag Chute

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A rear view of NASA's B-52 research aircraft deploying an experimental drag chute just after landing on Rogers Dry Lake, adjacent to the Dryden Flight Research Center, Edwards, California, on a 1990 research flight. The B-52's tests led to the development of a drag chute to help the Space Shuttle land more safely and easily. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid

  7. B-52 stability augmentation system reliability

    NASA Technical Reports Server (NTRS)

    Bowling, T. C.; Key, L. W.

    1976-01-01

    The B-52 SAS (Stability Augmentation System) was developed and retrofitted to nearly 300 aircraft. It actively controls B-52 structural bending, provides improved yaw and pitch damping through sensors and electronic control channels, and puts complete reliance on hydraulic control power for rudder and elevators. The system has experienced over 300,000 flight hours and has exhibited service reliability comparable to the results of the reliability test program. Development experience points out numerous lessons with potential application in the mechanization and development of advanced technology control systems of high reliability.

  8. 21 CFR 25.52 - Environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Environmental impact statements. 25.52 Section 25... ENVIRONMENTAL IMPACT CONSIDERATIONS Public Participation and Notification of Environmental Documents § 25.52 Environmental impact statements. (a) If FDA determines that an EIS is necessary for an action involving...

  9. Wind-Tunnel Results of the B-52B with the X-43A Stack

    NASA Technical Reports Server (NTRS)

    Davis, Mark C.; Sim, Alexander G.; Rhode, Matthew; Johnson, Kevin D., Sr.

    2007-01-01

    A low-speed wind-tunnel test was performed with a 3%-scale model of a booster rocket mated to an X-43A research vehicle, a combination referred to as the Hyper-X launch vehicle. The test was conducted both in freestream air and in the presence of a partial model of the B-52B airplane. The objectives of the test were to obtain force and moment data to generate structural loads affecting the pylon of the B-52B airplane and to determine the aerodynamic influence of the B-52B on the Hyper-X launch vehicle for evaluating launch separation characteristics. The windtunnel test was conducted at a low-speed wind tunnel in Hampton, Virginia. All moments and forces reported are based either on the aerodynamic influence of the B-52B airplane or are for the Hyper-X launch vehicle in freestream air. Overall, the test showed that the B-52B airplane imparts a strong downwash onto the Hyper-X launch vehicle, reducing the net lift of the Hyper-X launch vehicle. Pitching and rolling moments are also imparted onto the booster and are a strong function of the launch-drop angle of attack.

  10. Dryden B-52 Launch Aircraft in Flight over Dryden

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable B-52 mothership flies over the main building at the Dryden Flight Research Center, Edwards, California. The B-52, used for launching experimental aircraft and for other flight research projects, has been a familiar sight in the skies over Edwards for more than 40 years and has also been both the oldest B-52 still flying and the aircraft with the lowest flight time of any B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of

  11. Pegasus Mated to B-52 Mothership - First Flight

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The Pegasus air-launched space booster is carried aloft under the right wing of NASA's B-52 carrier aircraft on its first captive flight from the Dryden Flight Research Center, Edwards, California. The first of two scheduled captive flights was completed on November 9, 1989. Pegasus is used to launch satellites into low-earth orbits cheaply. In 1997, a Pegasus rocket booster was also modified to test a hypersonic experiment (PHYSX). An experimental 'glove,' installed on a section of its wing, housed hundreds of temperature and pressure sensors that sent hypersonic flight data to ground tracking facilities during the experiment's flight. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering

  12. X-15 Mated to B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1959-01-01

    One of three X-15 rocket-powered research aircraft being carried aloft under the wing of its B-52 mothership. The X-15 was air launched from the B-52 so the rocket plane would have enough fuel to reach its high speed and altitude test points. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. The X-15s made a total of 199 flights over a period of nearly 10 years and set world's unofficial speed and altitude records of 4,520 miles per hour (Mach 6.7) and 354,200 feet. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo manned spaceflight programs and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development

  13. Wind Tunnel Results of the B-52B with the X-43A Stack

    NASA Technical Reports Server (NTRS)

    Davis, Mark C.; Sim, Alexander G.; Rhode, Matthew; Johnson, Kevin D.

    2006-01-01

    A low-speed wind-tunnel test was performed with a three-percent-scale model of a booster rocket mated to an X-43A research vehicle, a combination referred to as the Hyper-X launch vehicle. The test was conducted both in free-stream air and in the presence of a partial model of the B-52B airplane. The objectives of the test were to obtain force and moment data to generate structural loads affecting the pylon of the B-52B airplane and to determine the aerodynamic influence of the B-52B airplane on the Hyper-X launch vehicle to evaluate launch separation characteristics. The wind-tunnel test was conducted at a low-speed wind tunnel in Hampton, Virginia. All moments and forces reported are based either on the aerodynamic influence of the B-52B airplane or are for the Hyper-X launch vehicle in free-stream air. Overall, the test showed that the B-52B airplane imparts a strong downwash onto the Hyper-X launch vehicle, reducing the net lift of the Hyper-X launch vehicle. Also, pitching and rolling moments are imparted onto the booster and are a strong function of the launch-drop angle of attack.

  14. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  15. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  16. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  17. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  18. 42 CFR 52b.5 - How will NIH evaluate applications?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How will NIH evaluate applications? 52b.5 Section 52b.5 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.5 How will NIH evaluate applications? (a) In evaluating and...

  19. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  20. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  1. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  2. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  3. 42 CFR 52b.3 - Who is eligible to apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply? 52b.3 Section 52b.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.3 Who is eligible to apply? In order to be eligible for a...

  4. X-15 Mated to B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1960-01-01

    High-altitude contrails frame the B-52 mothership as it carries the X-15 aloft for a research flight on 13 April 1960 on Air Force Maj. Robert M. White's first X-15 flight. The X-15s were air-launched so that they would have enough rocket fuel to reach their high speed and altitude test points. For this early research flight, the X-15 was equipped with a pair of XLR-11 rocket engines until the XLR-99 was available. The X-15s made a total of 199 flights over a period of nearly 10 years--1959 to 1968--and set unofficial world speed and altitude records of 4,520 mph (Mach 6.7) and 354,200 feet. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo piloted spaceflight programs, and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several

  5. B-52 Flight Mission Symbology on Side of Craft

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A view of some of the mission markings, painted on the side of NASA's B-52 mothership, that tell the story of its colorful history. Just as combat aircraft would paint a bomb on the side of an aircraft for each bombing mission completed, NASA crew members painted a silhouette on the side of the B-52's fuselage to commemorate each drop of an X-15, lifting body, remotely piloted research vehicle, X-38 crew return vehicle, or other experimental vehicle or parachute system. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for

  6. Dryden B-52 Launch Aircraft on Edwards AFB Runway

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable workhorse, the B-52 mothership, rolls out on the Edwards AFB runway after a test flight in 1996. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the X-38, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  7. X-38 Mounted on Pylon of B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A close-up view of the X-38 research vehicle mounted under the wing of the B-52 mothership prior to a 1997 test flight. The X-38, which was designed to help develop technology for an emergency crew return vehicle (CRV) for the International Space Station, is one of many research vehicles the B-52 has carried aloft over the past 40 years. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space

  8. Spin Research Vehicle (SRV) in B-52 Captive Flight

    NASA Technical Reports Server (NTRS)

    1981-01-01

    This in-flight photo of NASA's B-52 mothership shows the bomber carrying a subscale model of an Air Force F-15, a remotely piloted vehicle that was used to conduct spin research. The F-15 Remotely Piloted Research Vehicles (RPRV) was air launched from the B-52 at approximately 45,000 feet and was controlled by a pilot in a ground cockpit complete with flight controls and a television screen. The F-15 model in this particular configuration was known as the Spin Research Vehicle (SRV). NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST

  9. Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey.

    PubMed

    Sahin, Ziver; Bıcakcıgil, Muge; Aksu, Kenan; Kamali, Sevil; Akar, Servet; Onen, Fatos; Karadag, Omer; Ozbalkan, Zeynep; Ates, Askin; Ozer, Huseyin Te; Yilmaz, Vuslat; Seyahi, Emire; Ozturk, Mehmet A; Cefle, Ayse; Cobankara, Veli; Onat, A Mesut; Tunc, Ercan; Düzgün, Nursen; Aydin, Sibel Z; Yilmaz, Neslihan; Fresko, İzzet; Karaaslan, Yasar; Kiraz, Sedat; Akkoc, Nurullah; Inanc, Murat; Keser, Gokhan; Uyar, F Aytul; Direskeneli, Haner; Saruhan-Direskeneli, Güher

    2012-02-06

    HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they are associated with two different vasculitides (HLA-B*51 in Behçet's disease and HLA-B*52 in Takayasu's arteritis (TAK)) and with major clinical and immunological differences. In this study, we aimed to screen a large cohort of TAK patients from Turkey for the presence of HLA-B*51 and HLA-B*52 as susceptibility and severity factors. TAK patients (n = 330) followed at a total of 15 centers were included in the study. The mean age of the patients was 37.8 years, and 86% were women. DNA samples from the patients and healthy controls (HC; n = 210) were isolated, and the presence of HLA-B*51 or HLA-B*52 was screened for by using PCR with sequence-specific primers. We found a significant association of HLA-B*52 with TAK (20.9% vs HC = 6.7%, P = 0.000, OR = 3.7, 95% CI = 2.02 to 6.77). The distribution of HLA-B*51 did not differ between TAK patients and HCs (22.7% vs 24.8%, OR = 0.9, 95% CI = 0.60 to 1.34). The presence of HLA-B*52 decreased in late-onset patients (> 40 years of age; 12.0%, P = 0.024, OR = 0.43, 95% CI = 0.20 to 0.91). Patients with angiographic type I disease with limited aortic involvement also had a lower presence of HLA-B*52 compared to those with all other disease subtypes (13.1% vs 26%, P = 0.005, OR = 0.43, 95% CI = 0.23 to 0.78). In this study, the previously reported association of TAK with HLA-B*52 in other populations was confirmed in patients from Turkey. The functional relevance of HLA-B*52 in TAK pathogenesis needs to be explored further.

  10. Pegasus Engine Ignites after Drop from B-52 Mothership

    NASA Image and Video Library

    1991-07-17

    Against the midnight blue of a high-altitude sky, Orbital Sciences’ Pegasus winged rocket booster ignites after being dropped from NASA’s B-52 mothership on a July 1991 flight. A NASA chase plane for the flight is also visible above the rocket and below the B-52.

  11. B-52B/DTV (Drop Test Vehicle) flight test results: Drop test missions

    NASA Technical Reports Server (NTRS)

    Doty, L. J.

    1985-01-01

    The NASA test airplane, B-52B-008, was a carrier for drop tests of the shuttle booster recovery parachute system. The purpose of the test support by Boeing was to monitor the vertical loads on the pylon hooks. The hooks hold the Drop Test Vehicle to the B-52 pylon during drop test missions. The loads were monitored to assure the successful completion of the flight and the safety of the crew.

  12. Foam suppression in overloaded manure-based biogas reactors using antifoaming agents.

    PubMed

    Kougias, P G; Boe, K; Tsapekos, P; Angelidaki, I

    2014-02-01

    Foam control is an imperative need in biogas plants, as foaming is a major operational problem. In the present study, the effect of oils (rapeseed oil, oleic acid, and octanoic acid) and tributylphosphate on foam reduction and process performance in batch and continuous manure-based biogas reactors was investigated. The compounds were tested in dosages of 0.05%, 0.1% and 0.5% v/vfeed. The results showed that rapeseed oil was most efficient to suppress foam at the dosage of 0.05% and 0.1% v/vfeed, while octanoic acid was most efficient to suppress foam at dosage of 0.5% v/vfeed. Moreover, the addition of rapeseed oil also increased methane yield. In contrast, tributylphosphate, which was very efficient antifoam, was found to be inhibitory to the biogas process. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. X-38 Mounted on Pylon of B-52 Mothership

    NASA Image and Video Library

    1997-07-06

    A close-up view of the X-38 research vehicle mounted under the wing of the B-52 mothership prior to a 1997 test flight. The X-38, which was designed to help develop technology for an emergency crew return vehicle (CRV) for the International Space Station, is one of many research vehicles the B-52 has carried aloft over the past 40 years.

  14. X-38 on B-52 Wing Pylon - View from Observation Window

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A unique, close-up view of the X-38 under the wing of NASA's B-52 mothership prior to launch of the lifting-body research vehicle. The photo was taken from the observation window of the B-52 bomber as it banked in flight. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In

  15. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  16. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  17. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  18. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  19. 42 CFR 52b.1 - To what programs do these regulations apply?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false To what programs do these regulations apply? 52b.1 Section 52b.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.1 To what programs do these regulations apply? (a) General...

  20. Status of display systems in B-52H

    NASA Astrophysics Data System (ADS)

    Hopper, Darrel G.; Meyer, Frederick M.; Wodke, Kenneth E.

    1999-08-01

    Display technologies for the B-52 were selected some 40 years ago have become unsupportable. Electromechanical and old cathode ray tube technologies, including an exotic six-gun 13 in. tube, have become unsupportable due to the vanishing vendor syndrome. Thus, it is necessary to insert new technologies which will be available for the next 40 years to maintain the capability heretofore provided by those now out of favor with the commercial sector. With this paper we begin a look at the status of displays in the B-52H, which will remain in inventory until 2046 according to current plans. From a component electronics technology perspective, such as displays, the B-52H provides several 10-year life cycle cost (LCC) planning cycles to consider multiple upgrades. Three Productivity, Reliability, Availability, and Maintainability (PRAM) projects are reviewed to replace 1950s CRTs in several sizes: 3, 9, and 13 in. A different display technology has been selected in each case. Additional display upgrades in may be anticipated and are discussed.

  1. The effects of aircraft (B-52) overflights on ancient structures

    NASA Astrophysics Data System (ADS)

    Battis, J. C.

    1994-03-01

    To simulate combat missions for the American bomber force, the Air Combat Command conducts low altitude training flights along routes throughout the U.S.A. This paper presents the results of an effort to evaluate the effect of these overflights on the many archaeologically significant structures located beneath the training routes. This study has shown that: (1) low overflights can induce measurable vibrations in these ancient structures; (2) the overflight induced motions do not constitute an appreciable threat to the sites; and (3) the observed levels of motion are no greater than those induced by sources in the natural environment. Although these findings are specific to overflights by B-52s, comparison of the low frequency acoustic signature of the B-52 and that of the B-1B overflights should not pose a significantly greater threat to the structures than B-52 overflights.

  2. M2-F2 Mated to B-52 Mothership on Ramp

    NASA Technical Reports Server (NTRS)

    1965-01-01

    A head-on view of the M2-F2 lifting body mounted on the wing pylon of its B-52 mothership in 1965. This was for a captive flight made the following month. The M2-F2 remained attached to the B-52 throughout the flight to test its on-board systems. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute

  3. X-38 Ship #2 Mated to B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This photo shows one of the X-38 lifting-body research vehicles mated to NASA's B-52 mothership in flight prior to launch. The B-52 has been a workhorse for the Dryden Flight Research Center for more than 40 years, carrying numerous research vehicles aloft and conducting a variety of other research flight experiments. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  4. X-38 on B-52 Wing Pylon - View from Observation Window

    NASA Image and Video Library

    1997-11-19

    A unique, close-up view of the X-38 under the wing of NASA's B-52 mothership prior to launch of the lifting-body research vehicle. The photo was taken from the observation window of the B-52 bomber as it banked in flight.

  5. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  6. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  7. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  8. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  9. 42 CFR 52b.6 - What is the rate of federal financial participation?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What is the rate of federal financial participation? 52b.6 Section 52b.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.6 What is the rate of federal financial...

  10. X-15 on Lakebed after Landing with B-52 Mothership Flyover

    NASA Technical Reports Server (NTRS)

    1961-01-01

    As crew members secure the X-15 rocket-powered aircraft after a research flight, the B-52 mothership used for launching this unique aircraft does a low fly-by overhead. The X-15s made a total of 199 flights over a period of nearly 10 years -- 1959 to 1968 -- and set unofficial world speed and altitude records of 4,520 mph (Mach 6.7) and 354,200. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo piloted spaceflight programs, and also the Space Shuttle program. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable

  11. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  12. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  13. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  14. 42 CFR 52b.10 - What are the terms and conditions of awards?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the terms and conditions of awards? 52b.10 Section 52b.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.10 What are the terms and conditions of awards? In...

  15. Final Report - "Foaming and Antifoaming and Gas Entrainment in Radioactive Waste Pretreatment and Immobilization Processes"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wasan, Darsh T.

    2007-10-09

    study the effectiveness of three slurry rheology modifiers. An effective modifier was identified which resulted in lowering the yield stress of the waste simulant. Therefore, the results of this research have led to the basic understanding of the foaming/antifoaming mechanism in waste slurries as well as identification of a rheology modifier, which enhances the processing throughput, and accelerates the DOE mission. The objectives of this research effort were to develop a fundamental understanding of the physico-chemical mechanisms that produced foaming and air entrainment in the DOE High Level (HLW) and Low Activity (LAW) radioactive waste separation and immobilization processes, and to develop and test advanced antifoam/defoaming/rheology modifier agents. Antifoams/rheology modifiers developed from this research ere tested using non-radioactive simulants of the radioactive wastes obtained from Hanford and the Savannah River Site (SRS).« less

  16. 48 CFR 52.247-34 - F.o.b. Destination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination. 52.247....o.b. Destination. As prescribed in 47.303-6(c), insert the following clause: F.o.b. Destination (JAN 1991) (a) The term f.o.b. destination, as used in this clause, means— (1) Free of expense to the...

  17. X-38 Ship #2 Mated to B-52 Mothership in Flight

    NASA Image and Video Library

    1999-07-09

    This photo shows one of the X-38 lifting-body research vehicles mated to NASA's B-52 mothership in flight prior to launch. The B-52 has been a workhorse for the Dryden Flight Research Center for more than 40 years, carrying numerous research vehicles aloft and conducting a variety of other research flight experiments.

  18. HiMAT Subscale Research Vehicle Mated to B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The Highly Maneuverable Aircraft Technology (HiMAT) research vehicle is shown here mated to a wing pylon on NASA's B-52 mothership aircraft. The HiMAT was a technology demonstrator to test structures and configurations for advanced fighter concepts. Over the course of more than 40 years, the B-52 proved a valuable workhorse for NASA's Dryden Flight Research Center (under various names), launching a wide variety of vehicles and conducting numerous other research flights. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for

  19. 48 CFR 52.247-29 - F.o.b. Origin.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin. 52.247-29....o.b. Origin. As prescribed in 47.303-1(c), insert the following clause: F.o.b. Origin (FEB 2006) (a) The term f.o.b. origin, as used in this clause, means free of expense to the Government delivered— (1...

  20. Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells.

    PubMed

    Nielsen, Jens Christian; Senne de Oliveira Lino, Felipe; Rasmussen, Thomas Gundelund; Thykær, Jette; Workman, Christopher T; Basso, Thiago Olitta

    2017-11-01

    The Brazilian sugarcane industry constitutes one of the biggest and most efficient ethanol production processes in the world. Brazilian ethanol production utilizes a unique process, which includes cell recycling, acid wash, and non-aseptic conditions. Process characteristics, such as extensive CO 2 generation, poor quality of raw materials, and frequent contaminations, all lead to excessive foam formation during fermentations, which is treated with antifoam agents (AFA). In this study, we have investigated the impact of industrial AFA treatments on the physiology and transcriptome of the industrial ethanol strain Saccharomyces cerevisiae CAT-1. The investigated AFA included industrially used AFA acquired from Brazilian ethanol plants and commercially available AFA commonly used in the fermentation literature. In batch fermentations, it was shown that industrial AFA compromised growth rates and glucose uptake rates, while commercial AFA had no effect in concentrations relevant for defoaming purposes. Industrial AFA were further tested in laboratory scale simulations of the Brazilian ethanol production process and proved to decrease cell viability compared to the control, and the effects were intensified with increasing AFA concentrations and exposure time. Transcriptome analysis showed that AFA treatments induced additional stress responses in yeast cells compared to the control, shown by an up-regulation of stress-specific genes and a down-regulation of lipid biosynthesis, especially ergosterol. By documenting the detrimental effects associated with chemical AFA, we highlight the importance of developing innocuous systems for foam control in industrial fermentation processes.

  1. 42 CFR 52b.12 - What are the minimum requirements of construction and equipment?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the minimum requirements of construction and equipment? 52b.12 Section 52b.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.12 What are the minimum...

  2. Ro52-mediated Monoubiquitination of IKKβ Down-regulates NF-κB Signalling

    PubMed Central

    Wada, Keiji; Niida, Motoko; Tanaka, Makoto; Kamitani, Tetsu

    2009-01-01

    Upon activation, NF-κB translocates into the nucleus and initiates biological events. This NF-κB signalling is mainly regulated by the protein kinase IKKβ. Early in this signalling pathway, IKKβ is phosphorylated for activation by several factors, such as pro-inflammatory cytokines and the Tax oncoprotein of HTLV-1. In cells infected by HTLV-1, IKKβ is persistently phosphorylated and conjugated with monoubiquitin due to Tax expression. Although this Tax-induced monoubiquitination appears to be an important regulation system for IKKβ, how the monoubiquitination occurs is unknown and its role in NF-κB signalling is still unclear. Here, we show that an E3-ubiquitin ligase Ro52 interacts weakly with wild-type IKKβ but strongly with a phosphomimetic mutant IKKβ to conjugate monoubiquitin in cooperation with an E2-ubiquitin-conjugating enzyme UbcH5B. These results suggest that the Tax-induced phosphorylation of IKKβ causes an interaction with Ro52 for the subsequent monoubiquitination. NF-κB reporter assays have shown that the IKKβ activity is suppressed by wild-type Ro52, but not by its inactive mutant. In addition, monoubiquitin fusion of IKKβ reduced its activity for NF-κB signalling. We also found that Ro52 dramatically reduces the level of Tax. These results suggest that Ro52 down-regulates Tax-induced NF-κB signalling by monoubiquitinating IKKβ and by reducing the level of Tax. PMID:19675099

  3. [A new human leukocyte antigen class I allele, HLA- B*52:11].

    PubMed

    Li, Xiao-feng; Zhang, Xu; Zhang, Kun-lian; Chen, Yang; Liu, Xian-zhi; Li, Jian-ping

    2011-12-01

    To identify and confirm a novel HLA allele. A new human leukocyte antigen class I allele was found during routine HLA genotyping by polymerase chain reaction-sequence specific oligonucleotide probes (PCR-SSOP) and sequencing-based typing (SBT). The novel HLA-B*52 allele was identical to B*52:01:01 with an exception of one base substitution at position 583 of exon 3 where a C was changed to T resulting in codon 195 changed from CAC(H) to TAC(Y). A new HLA class I allele, B*52:11, is identified, and is named officially by the WHO Nomenclature Committee.

  4. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  5. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  6. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  7. 42 CFR 52b.7 - How is the grantee obligated to use the facility?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How is the grantee obligated to use the facility? 52b.7 Section 52b.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.7 How is the grantee obligated to use the...

  8. X-38 Ship #2 in Free Flight after Release from B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The X-38 research vehicle drops away from NASA's B-52 mothership immediately after being released from the B-52's wing pylon. More than 30 years earlier, this same B-52 launched the original lifting-body vehicles flight tested by NASA and the Air Force at what is now called the Dryden Flight Research Center and the Air Force Flight Test Center. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the

  9. M2-F3 In-flight Launch from B-52

    NASA Technical Reports Server (NTRS)

    1971-01-01

    This photo shows the M2-F3 Lifting Body being launched from NASA's B-52 mothership at the NASA Flight Research Center (FRC--now the Dryden Flight Research Center), Edwards, California. A fleet of lifting bodies flown at the FRC from 1963 to l975 demonstrated the ability of pilots to maneuver and safely land a wingless vehicle designed to fly back to Earth from space and be landed like an aircraft at a pre-determined site. Early flight testing of the M2-F1 and M2-F2 lifting body reentry configurations had validated the concept of piloted lifting body reentry from space. When the M2-F2 crashed on May 10, 1967, valuable information had already been obtained and was contributing to new designs. NASA pilots said the M2-F2 had lateral control problems, so when the M2-F2 was rebuilt at Northrop and redesignated the M2-F3, it was modified with an additional third vertical fin -- centered between the tip fins -- to improve control characteristics. First flight of the M2-F3, with NASA pilot Bill Dana at the controls, was June 2, 1970. The modified vehicle exhibited much better lateral stability and control characteristics than before, and only three glide flights were necessary before the first powered flight on Nov. 25, 1970. Over the next 26 missions, the M2-F3 reached a top speed of l,064 mph (Mach 1.6). Highest altitude reached by vehicle was 7l,500 feet on Dec. 20, 1972, the date of its last flight, with NASA pilot John Manke at the controls. NASA donated The M2-F3 vehicle to the Smithsonian Institute in December 1973. It is currently hanging in the Air and Space Museum along with the X-15 aircraft number 1, which was its hangar partner from 1965 to 1969. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most

  10. M2-F2 Lifting Body being Carried Aloft by B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1966-01-01

    The M2-F2 Lifting Body is shown here being carried aloft by the Air Force's B-52 (tail number 003) prior to a research launch. The success of Dryden's 'homebuilt' M2-F1 program led to NASA's development and construction of two heavyweight lifting bodies--the M2-F2 and the HL-10, both built by the Northrop Corporation. The 'M' refers to 'manned' and 'F' refers to 'flight' version. 'HL' comes from 'horizontal landing.' The first flight of the M2-F2--which looked much like the 'F1'--was on July 12, 1966. Milt Thompson was the pilot. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable

  11. Impact of Salt Waste Processing Facility Streams on the Nitric-Glycolic Flowsheet in the Chemical Processing Cell

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Martino, C.

    An evaluation of the previous Chemical Processing Cell (CPC) testing was performed to determine whether the planned concurrent operation, or “coupled” operations, of the Defense Waste Processing Facility (DWPF) with the Salt Waste Processing Facility (SWPF) has been adequately covered. Tests with the nitricglycolic acid flowsheet, which were both coupled and uncoupled with salt waste streams, included several tests that required extended boiling times. This report provides the evaluation of previous testing and the testing recommendation requested by Savannah River Remediation. The focus of the evaluation was impact on flammability in CPC vessels (i.e., hydrogen generation rate, SWPF solvent components,more » antifoam degradation products) and processing impacts (i.e., acid window, melter feed target, rheological properties, antifoam requirements, and chemical composition).« less

  12. An Analysis of Chronic Personnel Shortages in the B-52 Radar Navigator Career Field

    DTIC Science & Technology

    1987-03-01

    Weapon System Trainer - The new simulators for the B-52 located on some of the B-52 bases. Due to the complexity of the simulators, they have a small ...navigators crosstraining to these are lost to the B-52 career field. 21 ASTRA Every year a small number of radar navigators are chosen to attend one yerc at...this case, though, it turned up a small problem initially. The separation rates were obtained from Headquarters SAC (10), but did not include the number

  13. Treatment of diseases due to infections and old age using anti-foaming agents.

    PubMed

    Reinemann, Peter Joachim

    2003-06-01

    The biochemical changes taking place in the organism in the course of ageing and infectious processes result in substantial catabolic processes during which a variety of gases are created (in addition to carbon dioxide and nitrogen, depending on the conditions, methane, ammonia, hydrogen sulphide, mercaptan, etc. are also created) in addition to peptides and low molecular organic compounds. These gases are dispersed in the extra-cellular space and in the capillary system of blood and lymph in the form of micro-foam. The accompanied disturbance in the ability to flow considerably impairs the immune defence system which is inseparably connected to the transport of catabolic products. Any resulting diseases can be alleviated or even removed by the application of a simple physical-chemical principle. Anti-foaming agents (solutions, all types of dispersions, micro-emulsions) based on polydimethylsiloxane but also based on fatty acid esters (preferably unsaturated fatty acids) are proposed for treatment purposes.

  14. B-52/Pegasus with X-43A departing on first captive flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  15. B-52/Pegasus with X-43A in flight over Pacific Ocean.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  16. Close view of B-52/Pegasus with X-43A in flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  17. 48 CFR 52.247-45 - F.o.b. Origin and/or F.o.b. Destination Evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin and/or F.o.b... Clauses 52.247-45 F.o.b. Origin and/or F.o.b. Destination Evaluation. As prescribed in 47.305-2(b), insert the following provision in solicitations when offers are solicited on the basis of both f.o.b. origin...

  18. RelB is required for Peyer’s patch development: differential regulation of p52–RelB by lymphotoxin and TNF

    PubMed Central

    Yilmaz, Z.Buket; Weih, Debra S.; Sivakumar, Vallabhapurapu; Weih, Falk

    2003-01-01

    Targeted disruption of the Rel/NF-κB family members NF-κB2, encoding p100/p52, and RelB in mice results in anatomical defects of secondary lymphoid tissues. Here, we report that development of Peyer’s patch (PP)-organizing centers is impaired in both NF-κB2- and RelB-deficient animals. IL-7-induced expression of lymphotoxin (LT) in intestinal cells, a crucial step in PP development, is not impaired in RelB-deficient embryos. LTβ receptor (LTβR)-deficient mice also lack PPs, and we demonstrate that LTβR signaling induces p52–RelB and classical p50–RelA heterodimers, while tumor necrosis factor (TNF) activates only RelA. LTβR-induced binding of p52–RelB requires the degradation of the inhibitory p52 precursor, p100, which is mediated by the NF-κB-inducing kinase (NIK) and the IκB kinase (IKK) complex subunit IKKα, but not IKKβ or IKKγ. Activation of RelA requires all three IKK subunits, but is independent of NIK. Finally, we show that TNF increases p100 levels, resulting in the specific inhibition of RelB DNA binding via the C-terminus of p100. Our data indicate an important role of p52–RelB heterodimers in lymphoid organ development downstream of LTβR, NIK and IKKα. PMID:12505990

  19. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  20. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  1. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  2. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  3. 42 CFR 52b.11 - What are the requirements for acquisition and modernization of existing facilities?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What are the requirements for acquisition and modernization of existing facilities? 52b.11 Section 52b.11 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.11 What are the...

  4. Cockpit resource management skills enhance combat mission performance in a B-52 simulator

    NASA Technical Reports Server (NTRS)

    Povenmire, H. Kingsley; Rockway, Marty R.; Bunecke, Joseph L.; Patton, Mark W.

    1989-01-01

    A cockpit resource management (CRM) program for mission-ready B-52 aircrew is developed. The relationship between CRM performance and combat mission performance is studied. The performances of six crew members flying a simulated high workload mission in a B-52 weapon system trainer are evaluated. The data reveal that CRM performance enhances tactical maneuvers and bombing accuracy.

  5. Routine HLA-B genotyping with PCR-sequence-specific oligonucleotides detects a B*52 variant (B*5206).

    PubMed

    Hoelsch, K; Lenggeler, I; Pfannes, W; Knabe, H; Klein, H-G; Woelpl, A

    2005-05-01

    A new human leukocyte antigen (HLA)-B allele was found during routine typing of samples for a German unrelated bone marrow donor registry, the "Aktion Knochenmarkspende Bayern". After first interpretation of data of two independent low-resolution sequence-specific oligonucleotide typing tests, a B*51 variant was suggested. Further analysis via sequence-based typing identified the sequence as new B*52 allele. This new allele officially assigned as B*5206 differs from HLA-B*520102 by one nucleotide exchange in exon 2. The mutation is located at nucleotide position 274, at which a cytosine is substituted by a thymine leading to an amino acid change at protein position 67 from serine (TCC) to phenylalanine (TTC).

  6. B-52 control configured vehicles: Flight test results

    NASA Technical Reports Server (NTRS)

    Arnold, J. I.; Murphy, F. B.

    1976-01-01

    Recently completed B-52 Control Configured Vehicles (CCV) flight testing is summarized, and results are compared to analytical predictions. Results are presented for five CCV system concepts: ride control, maneuver load control, flutter mode control, augmented stability, and fatigue reduction. Test results confirm analytical predictions and show that CCV system concepts achieve performance goals when operated individually or collectively.

  7. Should bowel preparation, antifoaming agents, or prokinetics be used before video capsule endoscopy? A systematic review and meta-analysis.

    PubMed

    Kotwal, Vikram S; Attar, Bashar M; Gupta, Saurabh; Agarwal, Rajender

    2014-02-01

    The ideal bowel preparation regime before small bowel video capsule endoscopy (VCE) is not known. We carried out a systematic review and meta-analysis to study the effect of purgatives, antifoaming agents, and prokinetics on the outcomes associated with VCE. We performed literature searches in MEDLINE and Cochrane Library and included randomized-controlled trials studying the effect of purgatives, antifoaming agents, and prokinetics in patients undergoing VCE. Our outcomes of interest were visualization quality, diagnostic yield, and completion rate. Meta-analyses were carried out using the RevMan software and heterogeneity was assessed using the I statistic. Fifteen studies fulfilled the inclusion criteria. As compared with no bowel preparation, bowel preparation with polyethylene glycol (PEG) led to adequate visualization in a significantly higher number of patients undergoing VCE [odds ratio (OR) 3.13; 95% confidence interval (CI) 1.70-5.75]. Both PEG and sodium phosphate significantly improved the diagnostic yield (OR 1.68; 95% CI 1.16-2.42 and OR 1.77; 95% CI 1.18-2.64, respectively) but did not affect the completion rate. All studies with simethicone showed significantly improved visualization quality with its use as compared with overnight fasting or purgatives alone. Prokinetics did not significantly improve the completion rate of VCE. On the basis of the data available, a combination of PEG and simethicone appears to be the best approach for small bowel preparation before VCE. However, large multicenter randomized-controlled trials are needed to validate this recommendation and to evaluate the ideal dose of PEG and timing of bowel preparation before VCE. Prokinetics administered before VCE do not improve the completion rate and should not be used.

  8. X-15 drop launch, view from B-52 mothership

    NASA Technical Reports Server (NTRS)

    1960-01-01

    This roughly 20-second video clip shows the first planned glide flight of X-15 #1 on June 8, 1959. Then-North American pilot Scott Crossfield flew the mission, dropped from the B-52A mothership that bore the tail number 0003.

  9. 48 CFR 52.247-46 - Shipping Point(s) Used in Evaluation of F.o.b. Origin Offers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Evaluation of F.o.b. Origin Offers. 52.247-46 Section 52.247-46 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.247-46 Shipping Point(s) Used in Evaluation of F.o.b. Origin Offers. As prescribed in 47.305-3(b)(4)(ii), insert the following provision in f.o.b. origin solicitations...

  10. 42 CFR 52b.12 - What are the minimum requirements of construction and equipment?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and equipment? 52b.12 Section 52b.12 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... requirements of construction and equipment? (a) General. In addition to being subject to other laws... have been determined by the Director to constitute minimum requirements of construction and equipment...

  11. B-52/Pegasus with X-43A landing after first captive carry flight.

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden. After taking off from the Dryden Flight Research Center, Edwards, Calif., at 12:33 p.m. PDT, the B-52 soared off the California coast on the predetermined flight path, and returned to Dryden for a 2:19 p.m. PDT landing. Pending thorough evaluation of all flight data, this captive-carry test could lead to the first flight of the X-43A 'stack' as early as mid-May. The first free flight will be air-launched by NASA's B-52 at about 24,000 feet altitude. The booster will accelerate the X-43A to Mach 7 to approximately 95,000 feet altitude. At booster burnout, the X-43 will separate from the booster and fly under its own power on a preprogrammed flight path. The hydrogen-fueled aircraft has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  12. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  13. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  14. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  15. 40 CFR 60.52b - Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... metals, acid gases, organics, and nitrogen oxides. 60.52b Section 60.52b Protection of Environment... § 60.52b Standards for municipal waste combustor metals, acid gases, organics, and nitrogen oxides. (a... (total mass), corrected to 7 percent oxygen. (d) The limits for nitrogen oxides are specified in...

  16. 48 CFR 52.247-30 - F.o.b. Origin, Contractor's Facility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin, Contractor... Clauses 52.247-30 F.o.b. Origin, Contractor's Facility. As prescribed in 47.303-2(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. origin, contractor's facility: F.o...

  17. HiMAT Subscale Research Vehicle Mated to B-52 Mothership in Flight, Close-up View

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A close-up view of the Highly Maneuverable Aircraft Technology (HiMAT) research vehicle attached to a wing pylon on NASA's B-52 mothership during a 1980 test flight. The HiMAT used sharply swept-back wings and a canard configuration to test possible technology for advanced fighters. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported

  18. Preflight transient dynamic analyses of B-52 aircraft carrying Space Shuttle solid rocket booster drop-test vehicle

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1984-01-01

    This paper concerns the transient dynamic analysis of the B-52 aircraft carrying the Space Shuttle solid rocket booster drop test vehicle (SRB/DTV). The NASA structural analysis (NASTRAN) finite element computer program was used in the analysis. The B-52 operating conditions considered for analysis were (1) landing and (2) braking on aborted takeoff runs. The transient loads for the B-52 pylon front and rear hooks were calculated. The results can be used to establish the safe maneuver envelopes for the B-52 carrying the SRB/DTV in landings and brakings.

  19. Pre-flight transient dynamic analysis of B-52 carrying Space Shuttle solid rocket booster drop-test vehicle

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1983-01-01

    This paper concerns the transient dynamic analysis of the B-52 aircraft carrying the Space Shuttle solid-rocket booster drop-test vehicle (SRB/DTV). The NASA structural analysis (NASTRAN) finite-element computer program was used in the analysis. The B-52 operating conditions considered for analysis were (1) landing and (2) braking on aborted takeoff runs. The transient loads for the B-52 pylon front and rear hooks were calculated. The results can be used to establish the safe maneuver envelopes for the B-52 carrying the SRB/DTV in landings and brakings.

  20. B-52/Pegasus with X-43A in flight over Pacific Ocean

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  1. Close view of B-52/Pegasus with X-43A in flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  2. B-52/Pegasus with X-43A departing on first captive flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  3. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  4. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  5. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  6. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  7. 42 CFR 52b.8 - How will NIH monitor the use of facilities constructed with federal funds?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How will NIH monitor the use of facilities constructed with federal funds? 52b.8 Section 52b.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL INSTITUTES OF HEALTH CONSTRUCTION GRANTS § 52b.8 How will NIH...

  8. 52. LOOKING NORTHWEST FROM BETWEEN TRUSSES B AND C OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. LOOKING NORTHWEST FROM BETWEEN TRUSSES B AND C OF THEATER ATTIC. NOTE CURVE OF ELLIPTICAL CEILING BELOW, AIR SUPPLY DUCTS, AND LATERAL BRACING ADDED BETWEEN TRUSSES. - Auditorium Building, 430 South Michigan Avenue, Chicago, Cook County, IL

  9. 7 CFR 52.38b - Statistical sampling procedures for on-line inspection by attributes of processed fruits and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Statistical sampling procedures for on-line inspection by attributes of processed fruits and vegetables. 52.38b Section 52.38b Agriculture Regulations of... Regulations Governing Inspection and Certification Sampling § 52.38b Statistical sampling procedures for on...

  10. 7 CFR 52.38b - Statistical sampling procedures for on-line inspection by attributes of processed fruits and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Statistical sampling procedures for on-line inspection by attributes of processed fruits and vegetables. 52.38b Section 52.38b Agriculture Regulations of... Regulations Governing Inspection and Certification Sampling § 52.38b Statistical sampling procedures for on...

  11. Stress analyses of B-52 pylon hooks

    NASA Technical Reports Server (NTRS)

    Ko, W. L.; Schuster, L. S.

    1985-01-01

    The NASTRAN finite element computer program was used in the two dimensional stress analysis of B-52 carrier aircraft pylon hooks: (1) old rear hook (which failed), (2) new rear hook (improved geometry), (3) new DAST rear hook (derated geometry), and (4) front hook. NASTRAN model meshes were generated by the aid of PATRAN-G computer program. Brittle limit loads for all the four hooks were established. The critical stress level calculated from NASTRAN agrees reasonably well with the values predicted from the fracture mechanics for the failed old rear hook.

  12. Research Pilot Milt Thompson in M2-F2 Aircraft Attached to B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1966-01-01

    NASA research pilot Milt Thompson sits in the M2-F2 'heavyweight' lifting body research vehicle before a 1966 test flight. The M2-F2 and the other lifting-body designs were all attached to a wing pylon on NASA's B-52 mothership and carried aloft. The vehicles were then drop-launched and, at the end of their flights, glided back to wheeled landings on the dry lake or runway at Edwards AFB. The lifting body designs influenced the design of the Space Shuttle and were also reincarnated in the design of the X-38 in the 1990s. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft

  13. 48 CFR 52.247-35 - F.o.b. Destination, Within Consignee's Premises.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination, Within... Clauses 52.247-35 F.o.b. Destination, Within Consignee's Premises. As prescribed in 47.303-7(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. destination...

  14. 48 CFR 52.247-48 - F.o.b. Destination-Evidence of Shipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Destination... Provisions and Clauses 52.247-48 F.o.b. Destination—Evidence of Shipment. As prescribed in 47.305-4(c), insert the following clause: F.o.b. Destination—Evidence of Shipment (FEB 1999) (a) If this contract is...

  15. B-52/Pegasus with X-43A landing after first captive carry flight

    NASA Image and Video Library

    2001-04-28

    The NASA X-43A hypersonic research vehicle and its Pegasus booster rocket, mounted beneath the wing of their B-52 mothership, had a successful first captive-carry flight on April 28, 2001, Basically a dress rehearsal for a subsequent free flight, the captive-carry flight kept the X-43A-and-Pegasus combination attached to the B-52's wing pylon throughout the almost two-hour mission from NASA's Dryden Flight Research Center, Edwards, Calif., over the Pacific Missile Test Range, and back to Dryden.

  16. Operation Redwing -- Project 5. 2. In-flight participation of a B-52. Report for May-July 1956

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, F.L.

    1985-04-01

    The primary objective of this Project was to obtain measured-energy input and aircraft-response data on an instrumented B-52 aircraft when subjected to the thermal, blast, and gust effects of a nuclear explosion. To accomplish this, analysis was used in selecting the spatial location for the B-52, relative to a detonation, that would result in the desired aircraft inputs and responses. The B-52 was extensively instrumented with the major portion of the instrumentation devoted to measuring aircraft responses. The B-52 participated in nine shots, including one shot which the aircraft aborted just prior to time zero because of Bombing Navigation Systemmore » difficulties. The reliability of the instrumentation system was between 95% and 100% throughout the test program.« less

  17. A B-52H, tail number 61-0025, arrives at NASA's Dryden Flight Research Center after landing July 30,

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA Dryden Flight Research Center, Edwards, California, received an 'H' model B-52 Stratofortress aircraft on July 30, 2001. The B-52H will be used as an air-launch aircraft supporting NASA's flight research and advanced technology demonstration efforts. Dryden received the B-52H from the U.S. Air Force's (USAF) 23rd Bomb Squadron, 5th Bombardment Wing (Air Combat Command), located at Minot AFB, N.D. A USAF crew flew the aircraft to Dryden. The aircraft, USAF tail number 61-0025, will be loaned initially, then later transferred from the USAF to NASA. The B-52H is scheduled to leave Dryden Aug. 2 for de-militarization and Programmed Depot Maintenance (PDM) at Tinker Air Force Base (AFB), Oklahoma. The depot-level maintenance is scheduled to last about six months and includes a thorough maintenance and inspection process. The newly arrived B-52H is slated to replace Dryden's famous B-52B '008,' in the 2003-2004 timeframe. It will take about one year for the B-52H to be ready for flight research duties. This time includes PDM, construction of the new pylon, installation of the flight research instrumentation equipment, and aircraft envelope clearance flights.

  18. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Andy Blua and Jeff Doughty of Dryden's Experimental Fabrication Shop, along with B-52 Crew Chief Dan Bains and assistant Mark Thompson, all eye the new X-38 pylon during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California. The fit-check was the first time the 1,200-pound steel pylon, which was fabricated at Dryden, was mated to the B-52. The pylon served as an 'adapter' that allowed the X-38 to be attached to the B-52's wing. Earlier flight research vehicles had used the X-15 pylon for attachment to and launch from the B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the Hi

  19. Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.

    PubMed

    Chikata, Takayuki; Murakoshi, Hayato; Koyanagi, Madoka; Honda, Kazutaka; Gatanaga, Hiroyuki; Oka, Shinichi; Takiguchi, Masafumi

    2017-12-12

    HLA-B*52:01-C*12:02, which is found in approximately 20% of all Japanese persons, is well known to be associated with ulcerative colitis and Takayasu arteritis. This haplotype is also known to be protective in individuals infected with human immunodeficiency virus (HIV) type 1. Recent studies showed that HLA-B*52:01-restricted HIV-1-specific T cells suppress HIV-1 and that HLA-C*12:02 together with KIR2DL2 play an important role in natural killer cell-mediated control of HIV-1. However, the role of HLA-C*12:02-restricted cytotoxic T lymphocytes (CTLs) in suppressing HIV-1 replication remains unknown. In the present study, we demonstrated that HLA-C*12:02-restricted CTLs specific for 2 immunodominant epitopes, Pol IY11 and Nef MY9, contributed to the suppression of HIV-1 replication in HIV-1-infected individuals. Further analysis demonstrated that these 2 HLA-C*12:02-restricted CTLs together with 4 HLA-B*52:01-restricted ones effectively suppressed HIV-1 in individuals with the HLA-B*52:01-C*12:02 haplotype. Thus, both HLA-C*12:02 and HLA-B*52:01 alleles contribute to HIV-1 suppression via both HIV-1-specific CTLs and natural killer cells in individuals with this haplotype. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

  20. 57. Interior of launch control center, crew in B52 seats, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Interior of launch control center, crew in B-52 seats, looking east - Ellsworth Air Force Base, Delta Flight, Launch Control Facility, County Road CS23A, North of Exit 127, Interior, Jackson County, SD

  1. NASA's Brad Neal, X-43A Monitor Station Operator aboard NASA's B-52B mothership, performing pre-flight checks on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    NASA X-43A Monitor Station Operator Brad Neal performs final checks and pre-flight preparations aboard the B-52 for the third X-43A research vehicle Mach 10 flight on November 16, 2004. Takeoff of the B-52B mothership carrying the X-43A took place at 1 p.m., PST, with launch of the booster rocket/X-43A approximately an hour later.

  2. NF-κB Transcriptional Activity Is Modulated by FK506-binding Proteins FKBP51 and FKBP52

    PubMed Central

    Erlejman, Alejandra G.; De Leo, Sonia A.; Mazaira, Gisela I.; Molinari, Alejandro M.; Camisay, María Fernanda; Fontana, Vanina; Cox, Marc B.; Piwien-Pilipuk, Graciela; Galigniana, Mario D.

    2014-01-01

    Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to expand this model to other nuclear factors that are also subject to nuclear-cytoplasmic shuttling, we analyzed whether these immunophilins modulate NF-κB signaling. It is demonstrated that FKBP51 impairs both the nuclear translocation rate of NF-κB and its transcriptional activity. The inhibitory action of FKBP51 requires neither the peptidylprolyl-isomerase activity of the immunophilin nor its association with Hsp90. The TPR domain of FKBP51 is essential. On the other hand, FKBP52 favors the nuclear retention time of RelA, its association to a DNA consensus binding sequence, and NF-κB transcriptional activity, the latter effect being strongly dependent on the peptidylprolyl-isomerase activity and also on the TPR domain of FKBP52, but its interaction with Hsp90 is not required. In unstimulated cells, FKBP51 forms endogenous complexes with cytoplasmic RelA. Upon cell stimulation with phorbol ester, the NF-κB soluble complex exchanges FKBP51 for FKBP52, and the NF-κB biological effect is triggered. Importantly, FKBP52 is functionally recruited to the promoter region of NF-κB target genes, whereas FKBP51 is released. Competition assays demonstrated that both immunophilins antagonize one another, and binding assays with purified proteins suggest that the association of RelA and immunophilins could be direct. These observations suggest that the biological action of NF-κB in different cell types could be positively regulated by a high FKBP52/FKBP51 expression ratio by favoring NF-κB nuclear retention, recruitment to the promoter regions of target genes, and transcriptional activity. PMID:25104352

  3. Commercial winged booster to launch satellites from B-52

    NASA Astrophysics Data System (ADS)

    Covault, Craig

    1988-06-01

    A newly developed commercial winged space booster, the Pegasus, which will launch satellites from a B-52, is described. The booster will be able to launch a 600 lb, 72 in long craft into a 250 nm equatorial orbit. The Pegasus is 49.2 ft long with a 22 ft wing span and a weight of 40,000 lb. The winged design allows for an angle of attack of 20 degrees and a supersonic lift over drag ratio of 4:1. It operates with three solid rocket motors and will be launched from a B-52 at an altitude of 40,000 ft. The first motor provides an average of 112,000 lbs of thrust for about 82 seconds; burnout occurs at 208,000 ft and Mach 8.7. The third stage provides 9,000 lbs of thrust for 65 seconds, accelerating the vehicle into 25,000 fps orbital velocity. The first launch will be a 400 lb relay satellite targeted for July 1989 over the Pacific Ocean. Future launches will be possible from any site and will cost 10 million dollars. The Pegasus can also carry a 1500 payload at high altitude Mach cruise flights that do not achieve orbit, providing data to validate spaceplane conceptual fluid dynamic codes generated by computer.

  4. 48 CFR 52.247-38 - F.o.b. Inland Carrier, Point of Exportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Inland Carrier... Provisions and Clauses 52.247-38 F.o.b. Inland Carrier, Point of Exportation. As prescribed in 47.303-10(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. inland...

  5. 48 CFR 52.247-61 - F.o.b. Origin-Minimum Size of Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin-Minimum Size... Clauses 52.247-61 F.o.b. Origin—Minimum Size of Shipments. As prescribed in 47.305-16(c), insert the following clause in solicitations and contracts when volume rates may apply: F.o.b. Origin—Minimum Size of...

  6. 48 CFR 52.247-59 - F.o.b. Origin-Carload and Truckload Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin-Carload and... Clauses 52.247-59 F.o.b. Origin—Carload and Truckload Shipments. As prescribed in 47.305-16(a), insert the following clause in solicitations and contracts when it is contemplated that they may result in f.o.b...

  7. 48 CFR 52.247-39 - F.o.b. Inland Point, Country of Importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Inland Point... Provisions and Clauses 52.247-39 F.o.b. Inland Point, Country of Importation. As prescribed in 47.303-11(c), insert the following clause in solicitations and contracts when the delivery term is f.o.b. inland point...

  8. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Tom McMullen, Chief of Dryden's Experimental Fabrication Shop, makes adjustments to the new pylon for NASA's X-38 during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California, in 1997. The fit-check was the first time the 1,200-pound steel pylon was mated to the B-52 following fabrication at Dryden by the Center's Experimental Fabrication Shop. The pylon was built as an 'adapter' to allow the X-38 to be attached to and launched from the B-52's wing. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST

  9. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The new pylon for the X-38 following a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California, in 1997. The fit-check was the first time the 1,200-pound steel pylon was mated to the B-52 following fabrication at Dryden by the Center's Experimental Fabrication Shop. The pylon was built as an 'adapter' to allow the X-38 research vehicle to be carried aloft and launched from the B-52. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the

  10. Gamma Radiation from PSR B1055-52

    NASA Technical Reports Server (NTRS)

    Thompson, D. J.; Bailes, M.; Bertsch, D. L.; Cordes, J.; DAmico, N. D.; Esposito, J. A.; Finley, J.; Hartman, R. C.; Hermsen, W.; Kanbach, G.; hide

    1998-01-01

    The telescopes on the Compton Gamma Ray Observatory (CCRO) have observed PSR B1055-52 a number of times between 1991 and 1998. From these data, a more detailed picture of the gamma radiation from this source has been developed, showing several characteristics which distinguish this pulsar: the light curve is complex; there is no detectable unpulsed emission; the energy spectrum is flat, with no evidence of a sharp high-energy cutoff up to greater than 4 GeV. Comparisons of the gamma-ray data with observations at longer wavelengths show that no two of the known gamma-ray pulsars have quite the same characteristics; this diversity makes interpretation in terms of theoretical models difficult.

  11. Gamma Radiation from PSR B1055-52

    NASA Technical Reports Server (NTRS)

    Thompson, D. J.; Bailes, M.; Bertsch, D. L.; Cordes, J.; DAmico, N.; Esposito, J. A.; Finley, J.; Hartman, R. C.; Hermsen, W.; Kanbach, G.; hide

    1999-01-01

    The telescopes on the Compton Gamma Ray Observatory (CGRO) have observed PSR B1055-52 a number of times between 1991 and 1998. From these data, a more detailed picture of the gamma radiation from this source has been developed, showing several characteristics which distinguish this pulsar: the light curve is complex; there is no detectable unpulsed emission; the energy spectrum is flat, with no evidence of a sharp high-energy cutoff up to greater than 4 GeV. Comparisons of the gamma-ray data with observations at longer wavelengths show that no two of the known gamma-ray pulsars have quite the same characteristics; this diversity makes interpretation in terms of theoretical models difficult.

  12. Pegasus Mated to B-52 Mothership - First Flight

    NASA Image and Video Library

    1989-11-09

    The Pegasus air-launched space booster is carried aloft under the right wing of NASA's B-52 carrier aircraft on its first captive flight from the Dryden Flight Research Center, Edwards, California. The first of two scheduled captive flights was completed on November 9, 1989. Pegasus is used to launch satellites into low-earth orbits cheaply. In 1997, a Pegasus rocket booster was also modified to test a hypersonic experiment (PHYSX). An experimental "glove," installed on a section of its wing, housed hundreds of temperature and pressure sensors that sent hypersonic flight data to ground tracking facilities during the experiment’s flight.

  13. A B-52H, on loan to NASA's Dryden Flight Research Center, makes a pass down the runway prior to land

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA Dryden Flight Research Center, Edwards, California, received an 'H' model B-52 Stratofortress aircraft on July 30, 2001. The B-52H will be used as an air-launch aircraft supporting NASA's flight research and advanced technology demonstration efforts. Dryden received the B-52H from the U.S. Air Force's (USAF) 23rd Bomb Squadron, 5th Bombardment Wing (Air Combat Command), located at Minot AFB, N.D. A USAF crew flew the aircraft to Dryden. The aircraft, USAF tail number 61-0025, will be loaned initially, then later transferred from the USAF to NASA. The B-52H is scheduled to leave Dryden Aug. 2 for de-militarization and Programmed Depot Maintenance (PDM) at Tinker Air Force Base (AFB), Oklahoma. The depot-level maintenance is scheduled to last about six months and includes a thorough maintenance and inspection process. The newly arrived B-52H is slated to replace Dryden's famous B-52B '008,' in the 2003-2004 timeframe. It will take about one year for the B-52H to be ready for flight research duties. This time includes PDM, construction of the new pylon, installation of the flight research instrumentation equipment, and aircraft envelope clearance flights.

  14. Relationship of HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism with susceptibility to Takayasu arteritis: a meta-analysis.

    PubMed

    Chen, Si; Luan, Haixia; Li, Liubing; Zeng, Xiaoli; Wang, Tian; Li, Yongzhe; Yuan, Hui

    2017-01-01

    We performed a meta-analysis to determine whether combined evidence shows an association between HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism and the susceptibility to Takayasu arteritis (TA). Relevant articles dated November 2015 were acquired from the PubMed, Embase and Cochrane databases. The number of genotypes and/or alleles for HLA-B*51 and HLA-B*52 alleles and TNF-α-308 A/G polymorphism in cases and control subjects was extracted, and statistical analysis was conducted using STATA 11.2 software. We included 20 studies with 1864 TA patients and 6973 controls. The HLA-B*52 allele was found to be associated with TA (pooled OR 3.91, 95 % CI 3.22-4.74, P < 0.0001). The meta-analysis of TNF-α-308 A/G polymorphism for the A allele vs. G allele (P = 0.006) and AA + AG vs. GG (P = 0.023) revealed a significant association with TA. However, we did not find that the HLA-B*51 allele was associated with TA. This meta-analysis demonstrated that the HLA-B*52 allele and TNF-α-308 A/G polymorphism may contribute to TA susceptibility.

  15. 48 CFR 52.247-65 - F.o.b. Origin, Prepaid Freight-Small Package Shipments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Origin, Prepaid... Text of Provisions and Clauses 52.247-65 F.o.b. Origin, Prepaid Freight—Small Package Shipments. As prescribed in 47.303-17(f), insert the following clause: F.o.b. Origin Prepaid Freight—Small Package...

  16. Close-up of Wing Fit Check of Pylon to Carry the X-38 on B-52 Launch Aircraft

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Dryden Experimental Fabrication Shop's Andy Blua and Jeff Doughty make sure the new pylon for the X-38 fits precisely during a fit-check on NASA's B-52 at the Dryden Flight Research Center, Edwards, California in 1997. The 1,200-pound steel pylon, fabricated at Dryden, was an 'adapter' to allow the X-38 research vehicle to be carried aloft and launched from the bomber. The X-38 was a designed as a technology demonstrator to help develop an emergency Crew Return Vehicle for the International Space Station. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research

  17. Optimization of the polyplanar optical display electronics for a monochrome B-52 display

    NASA Astrophysics Data System (ADS)

    DeSanto, Leonard

    1998-09-01

    The Polyplanar Optical Display (POD) is a unique display screen which can be used with any projection source. The prototype ten-inch display is two inches thick and has a matte black face which allows for high contrast images. The prototype being developed is a form, fit and functional replacement display for the B-52 aircraft which uses a monochrome ten-inch display. In order to achieve a long lifetime, the new display uses a new 200 mW green solid-state laser (10,000 hr. life) at 532 nm as its light source. To produce real-time video, the laser light is being modulated by a Digital Light Processing (DLPTM) chip manufactured by Texas Instruments (TI). In order to use the solid-state laser as the light source and also fit within the constraints of the B-52 display, the Digital Micromirror Device (DMDTM) chip is operated remotely from the Texas Instruments circuit board. In order to achieve increased brightness a monochrome digitizing interface was investigated. The operation of the DMDTM divorced from the light engine and the interfacing of the DMDTM board with the RS-170 video format specific to the B-52 aircraft will be discussed, including the increased brightness of the monochrome digitizing interface. A brief description of the electronics required to drive the new 200 mW laser is also presented.

  18. 48 CFR 52.247-44 - F.o.b. Designated Air Carrier's Terminal, Point of Importation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Designated Air... CLAUSES Text of Provisions and Clauses 52.247-44 F.o.b. Designated Air Carrier's Terminal, Point of... the delivery term is f.o.b. designated air carrier's terminal, point of importation: F.o.b. Designated...

  19. 48 CFR 52.247-43 - F.o.b. Designated Air Carrier's Terminal, Point of Exportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Designated Air... CLAUSES Text of Provisions and Clauses 52.247-43 F.o.b. Designated Air Carrier's Terminal, Point of... the delivery term is f.o.b. designated air carrier's terminal, point of exportation: F.o.b. Designated...

  20. NASA's B-52B launch aircraft takes off carrying the third X-43A hypersonic research vehicle on a captive carry evaluation flight September 27, 2004

    NASA Image and Video Library

    2004-09-27

    Attached to the same B-52B mothership that once launched X-15 research aircraft in the 1960s, NASA's third X-43A performed a captive carry evaluation flight from Edwards Air Force Base, California on September 27, 2004. The X-43 remained mated to the B-52 throughout this mission, intended to check its readiness for launch scheduled later in the fall.

  1. Apolipoprotein B-52 mutation associated with hypobetalipoproteinemia is compatible with a misaligned pairing deletion mechanism.

    PubMed

    Groenewegen, W A; Krul, E S; Schonfeld, G

    1993-06-01

    We have identified a new truncation of apoB in a large kindred with hypobetalipoproteinemia that arose by an ambiguous deletion of one of four different groups of base-pairs. Eleven affected members of the kindred had total cholesterols (C) of 114 +/- 28, LDL-Cs of 46 +/- 21, and apoBs of 47 +/- 25 (all in mg/dl, mean +/- SD). These levels were lower (P < 0.0001) than in 15 unaffected relatives. On Western blotting, apoB-100 and a second major band corresponding to apoB-52 were seen in the affected individuals. The majority of the plasma apoB-52 was associated with a smaller than normal low density lipoprotein (LDL) particle. The molecular basis for this apoB-52 truncation is a 5-bp deletion, converting the sequence between cDNA nucleotide 7276 and 7283 from 5'-AAGTTAAG-3' into the mutant sequence 5'-AAG-3'. This results in a frameshift starting at amino acid residue 2357 and a termination codon at amino acid residue 2362. Deletion of one of four different groups of five consecutive bases, i.e., AAGTT, AGTTA, GTTAA, and TTAAG, all result in the same mutant sequence. Thus, the precise deletion is ambiguous. We propose that a misaligned pairing mechanism involving repeat sequences is compatible with this deletion mutation. We have noted similar ambiguous deletions associated with apoB-37, apoB-40, and a number of single base deletions and some may also be explained by a misaligned pairing mechanism. Small ambiguous deletions appear to constitute a major proportion of the apoB gene mutation spectrum suggesting that it may be a suitable model for studying the mechanisms of such mutations.

  2. Pesticide removal from waste spray-tank water by organoclay adsorption after field application: an approach for a formulation of cyprodinil containing antifoaming/defoaming agents.

    PubMed

    Suciu, Nicoleta A; Ferrari, Tommaso; Ferrari, Federico; Trevisan, Marco; Capri, Ettore

    2012-05-01

    Many reports on purification of water containing pesticides are based on studies using unformulated active ingredients. However, most commercial formulations contain additives/adjuvants or are manufactured using microencapsulation which may influence the purification process. Therefore, the main objective of this work was to develop and test a pilot scheme for decontaminating water containing pesticides formulated with antifoaming/defoaming agents. The Freundlich adsorption coefficients of formulation of cyprodinil, a new-generation fungicide, onto the organoclay Cloisite 20A have been determined in the laboratory in order to predict the efficiency of this organoclay in removing the fungicide from waste spray-tank water. Subsequently, the adsorption tests were repeated in the pilot system in order to test the practical operation of the purification scheme. The laboratory adsorption tests successfully predicted the efficiency of the pilot purification system, which removed more than 96% cyprodinil over a few hours. The passing of the organoclay-cyprodinil suspension through a layer of biomass gave 100% recovery of the organoclay at the surface of the biomass after 1 week. The organoclay was composted after the treatment to try to break down the fungicide so as to allow safe disposal of the waste, but cyprodinil was not significantly dissipated after 90 days. The purification scheme proved to be efficient for decontaminating water containing cyprodinil formulated with antifoaming/defoaming agents, but additional treatments for the adsorbed residues still appear to be necessary even for a moderately persistent pesticide such as cyprodinil. Furthermore, a significant conclusion of this study concerns the high influence of pesticide formulations on the process of purification of water containing these compounds, which should be taken into account when developing innovative decontamination schemes, especially for practical applications.

  3. Optimization of the polyplanar optical display electronics for a monochrome B-52 display

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DeSanto, L.

    The Polyplanar Optical Display (POD) is a unique display screen which can be used with any projection source. The prototype ten-inch display is two inches thick and has a matte black face which allows for high contrast images. The prototype being developed is a form, fit and functional replacement display for the B-52 aircraft which uses a monochrome ten-inch display. In order to achieve a long lifetime, the new display uses a new 200 mW green solid-state laser (10,000 hr. life) at 532 nm as its light source. To produce real-time video, the laser light is being modulated by amore » Digital Light Processing (DLP{trademark}) chip manufactured by Texas Instruments (TI). In order to use the solid-state laser as the light source and also fit within the constraints of the B-52 display, the Digital Micromirror Device (DMD{trademark}) chip is operated remotely from the Texas Instruments circuit board. In order to achieve increased brightness a monochrome digitizing interface was investigated. The operation of the DMD{trademark} divorced from the light engine and the interfacing of the DMD{trademark} board with the RS-170 video format specific to the B-52 aircraft will be discussed, including the increased brightness of the monochrome digitizing interface. A brief description of the electronics required to drive the new 200 mW laser is also presented.« less

  4. X-15 launch from B-52 mothership

    NASA Technical Reports Server (NTRS)

    1959-01-01

    This photo illustrates how the X-15 rocket-powered aircraft was taken aloft under the wing of a B-52. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at 45,000 ft and a speed of about 500 mph. This was one of the early powered flights using a pair of XLR-11 engines (until the XLR-99 became available). The X-15 was a rocket-powered aircraft 50 ft long with a wingspan of 22 ft. It was a missile-shaped vehicle with an unusual wedge-shaped vertical tail, thin stubby wings, and unique fairings that extended along the side of the fuselage. The X-15 weighed about 14,000 lb empty and approximately 34,000 lb at launch. The XLR-99 rocket engine, manufactured by Thiokol Chemical Corp., was pilot controlled and was capable of developing 57,000 lb of rated thrust (actual thrust reportedly climbed to 60,000 lb). North American Aviation built three X-15 aircraft for the program. The X-15 research aircraft was developed to provide in-flight information and data on aerodynamics, structures, flight controls, and the physiological aspects of high-speed, high-altitude flight. A follow-on program used the aircraft as a testbed to carry various scientific experiments beyond the Earth's atmosphere on a repeated basis. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls such as rudder surfaces on the vertical stabilizers to control yaw and canted horizontal surfaces on the tail to control pitch when moving in synchronization or roll when moved differentially. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at 45,000 ft and a speed of about 500 mph. Depending on the mission, the rocket engine provided thrust for

  5. 48 CFR 52.247-55 - F.o.b. Point for Delivery of Government-Furnished Property.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false F.o.b. Point for Delivery... Text of Provisions and Clauses 52.247-55 F.o.b. Point for Delivery of Government-Furnished Property. As prescribed in 47.305-12(a)(2), insert the following clause: F.o.b. Point for Delivery of Government-Furnished...

  6. NASA's B-52B launch aircraft takes off carrying the second X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on March 27, 2004

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif., on March 27, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 7.

  7. NASA's B-52B launch aircraft takes off carrying the third X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

  8. F-15 RPRV Attached Under the Wing of the B-52 Mothership in Flight

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This photograph shows one of NASA's 3/8th-scale F-15 remotely piloted research vehicles under the wing of the B-52 mothership in flight during 1973, the year that the research program began. The vehicle was used to make stall-spin studies of the F-15 shape before the actual F-15s began their flight tests. B-52 Project Description: NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle

  9. NF-KappaB2/p52 Activation and Androgen Receptor Signaling in Prostate Cancer

    DTIC Science & Technology

    2011-08-01

    biosynthetic enzymes including AKR1C3, CYP17A1, HSD3B2, and SRD5A1 were found to be elevated in CaP cells expressing NF-kappaB2/p52. Luciferase assays...RESULTS: Expression levels of androgen biosynthetic enzymes including AKR1C3, CYP17A1, HSD3B2, and SRD5A1 were found to be elevated in CaP cells

  10. 7 CFR 1948.52 - Objectives.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGULATIONS (CONTINUED) RURAL DEVELOPMENT Section 601 Energy Impacted Area Development Assistance Program § 1948.52 Objectives. The objective of the program is to help areas impacted by coal or uranium... 7 Agriculture 13 2014-01-01 2013-01-01 true Objectives. 1948.52 Section 1948.52 Agriculture...

  11. 7 CFR 1948.52 - Objectives.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGULATIONS (CONTINUED) RURAL DEVELOPMENT Section 601 Energy Impacted Area Development Assistance Program § 1948.52 Objectives. The objective of the program is to help areas impacted by coal or uranium... 7 Agriculture 13 2013-01-01 2013-01-01 false Objectives. 1948.52 Section 1948.52 Agriculture...

  12. 7 CFR 1948.52 - Objectives.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGULATIONS (CONTINUED) RURAL DEVELOPMENT Section 601 Energy Impacted Area Development Assistance Program § 1948.52 Objectives. The objective of the program is to help areas impacted by coal or uranium... 7 Agriculture 13 2012-01-01 2012-01-01 false Objectives. 1948.52 Section 1948.52 Agriculture...

  13. 7 CFR 1948.52 - Objectives.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REGULATIONS (CONTINUED) RURAL DEVELOPMENT Section 601 Energy Impacted Area Development Assistance Program § 1948.52 Objectives. The objective of the program is to help areas impacted by coal or uranium... 7 Agriculture 13 2011-01-01 2009-01-01 true Objectives. 1948.52 Section 1948.52 Agriculture...

  14. Scope of Work for Mk 28 FI Bomb and B52 Drop Test Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Draper, E.H.

    1965-10-04

    List of principles & responsibilities of this Sandia/AEC & Air Force joint program for verifying the functionability of the W28/AGM-28A/B-52 weapon system under actual routine handling, assembling, and firing during a stockpile-to-target sequence.

  15. 10 CFR 52.303 - Criminal penalties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the sections listed in paragraph (b) of this section. (b) The regulations in part 52 that are not... 10 Energy 2 2012-01-01 2012-01-01 false Criminal penalties. 52.303 Section 52.303 Energy NUCLEAR... Enforcement § 52.303 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

  16. 10 CFR 52.303 - Criminal penalties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the sections listed in paragraph (b) of this section. (b) The regulations in part 52 that are not... 10 Energy 2 2010-01-01 2010-01-01 false Criminal penalties. 52.303 Section 52.303 Energy NUCLEAR... Enforcement § 52.303 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

  17. Pegasus Engine Ignites after Drop from B-52 Mothership

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Against the midnight blue of a high-altitude sky, Orbital Sciences' Pegasus winged rocket booster ignites after being dropped from NASA's B-52 mothership on a July 1991 flight. A NASA chase plane for the flight is also visible above the rocket and below the B-52. Pegasus is an air-launched space booster produced by Orbital Sciences Corporation and Hercules Aerospace Company (initially; later, Alliant Tech Systems) to provide small satellite users with a cost-effective, flexible, and reliable method for placing payloads into low earth orbit. Pegasus has been used to launch a number of satellites and the PHYSX experiment. That experiment consisted of a smooth glove installed on the first-stage delta wing of the Pegasus. The glove was used to gather data at speeds of up to Mach 8 and at altitudes approaching 200,000 feet. The flight took place on October 22, 1998. The PHYSX experiment focused on determining where boundary-layer transition occurs on the glove and on identifying the flow mechanism causing transition over the glove. Data from this flight-research effort included temperature, heat transfer, pressure measurements, airflow, and trajectory reconstruction. Hypersonic flight-research programs are an approach to validate design methods for hypersonic vehicles (those that fly more than five times the speed of sound, or Mach 5). Dryden Flight Research Center, Edwards, California, provided overall management of the glove experiment, glove design, and buildup. Dryden also was responsible for conducting the flight tests. Langley Research Center, Hampton, Virginia, was responsible for the design of the aerodynamic glove as well as development of sensor and instrumentation systems for the glove. Other participating NASA centers included Ames Research Center, Mountain View, California; Goddard Space Flight Center, Greenbelt, Maryland; and Kennedy Space Center, Florida. Orbital Sciences Corporation, Dulles, Virginia, is the manufacturer of the Pegasus vehicle, while

  18. HL-10 on lakebed with B-52 flyby

    NASA Technical Reports Server (NTRS)

    1969-01-01

    NASA research pilot Bill Dana takes a moment to watch NASA's NB-52B cruise overhead after a research flight in the HL-10. On the left, John Reeves can be seen at the cockpit of the lifting body. The HL-10 was one of five heavyweight lifting-body designs flown at NASA's Flight Research Center (FRC--later Dryden Flight Research Center), Edwards, California, from July 1966 to November 1975 to study and validate the concept of safely maneuvering and landing a low lift-over-drag vehicle designed for reentry from space. Northrop Corporation built the HL-10 and M2-F2, the first two of the fleet of 'heavy' lifting bodies flown by the NASA Flight Research Center. The contract for construction of the HL-10 and the M2-F2 was $1.8 million. 'HL' stands for horizontal landing, and '10' refers to the tenth design studied by engineers at NASA's Langley Research Center, Hampton, Va. After delivery to NASA in January 1966, the HL-10 made its first flight on Dec. 22, 1966, with research pilot Bruce Peterson in the cockpit. Although an XLR-11 rocket engine was installed in the vehicle, the first 11 drop flights from the B-52 launch aircraft were powerless glide flights to assess handling qualities, stability, and control. In the end, the HL-10 was judged to be the best handling of the three original heavy-weight lifting bodies (M2-F2/F3, HL-10, X-24A). The HL-10 was flown 37 times during the lifting body research program and logged the highest altitude and fastest speed in the Lifting Body program. On Feb. 18, 1970, Air Force test pilot Peter Hoag piloted the HL-10 to Mach 1.86 (1,228 mph). Nine days later, NASA pilot Bill Dana flew the vehicle to 90,030 feet, which became the highest altitude reached in the program. Some new and different lessons were learned through the successful flight testing of the HL-10. These lessons, when combined with information from it's sister ship, the M2-F2/F3, provided an excellent starting point for designers of future entry vehicles, including the

  19. 52. G.E.H. photographer August 1930 1HUM1B #59, OILING OPERATIONS, GEH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. G.E.H. photographer August 1930 1-HUM-1-B #59, OILING OPERATIONS, GEH 8-30. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  20. NASA's B-52B launch aircraft cruises to a test range over the Pacific Ocean carrying the third X-43A vehicle attached to a Pegasus rocket on November 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft, attached to a modified Pegasus booster rocket, was taken to launch altitude by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was released from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

  1. A wind-tunnel investigation of a B-52 model flutter suppression system

    NASA Technical Reports Server (NTRS)

    Redd, L. T.; Gilman, J., Jr.; Cooley, D. E.; Sevart, F. D.

    1974-01-01

    Flutter modeling techniques have been successfully extended to the difficult case of the active suppression of flutter. The demonstration was conducted in a transonic dynamics tunnel using a 1/30 scale, elastic, dynamic model of a Boeing B-52 control configured vehicle. The results from the study show that with the flutter suppression system operating there is a substantial increase in the damping associated with the critical flutter mode. The results also show good correlation between the damping characteristics of the model and the aircraft.

  2. Analysis and testing of aeroelastic model stability augmentation systems. [for supersonic transport aircraft wing and B-52 aircraft control system

    NASA Technical Reports Server (NTRS)

    Sevart, F. D.; Patel, S. M.

    1973-01-01

    Testing and evaluation of a stability augmentation system for aircraft flight control were performed. The flutter suppression system and synthesis conducted on a scale model of a supersonic wing for a transport aircraft are discussed. Mechanization and testing of the leading and trailing edge surface actuation systems are described. The ride control system analyses for a 375,000 pound gross weight B-52E aircraft are presented. Analyses of the B-52E aircraft maneuver load control system are included.

  3. Foam and its mitigation in fermentation systems.

    PubMed

    Junker, Beth

    2007-01-01

    Key aspects of foaming and its mitigation in fermentation systems are presented. Foam properties and behavior, conditions that affect foaming, and consequences of foaming are discussed, followed by methods to detect and prevent foam, both without and with the use of antifoam, and their implications. Antifoams were catalogued according to their class (e.g., polyalkylene glycols, silicone emulsions, etc.) to facilitate recognition of antifoams possessing similar base compositions. Relatively few published studies directly comparing antifoams experimentally are available, but those reports found only partially identify clear benefits/disadvantages of any one antifoam type. Consequently, desired characteristics, trends in antifoam application, and chemical types of antifoams are evaluated on the basis of a thorough review of available literature reports describing a specific antifoam's usage. Finally, examples of specific foaming situations taken from both the literature and from actual experience in an industrial fermentation pilot plant are examined for their agreement with expected behavior.

  4. Antimicrobial activities of bacteriocins E50-52 and B602 against MRSA and other nosocomial infections

    USDA-ARS?s Scientific Manuscript database

    Our objective was to determine the antimicrobial activities of previously published bacteriocins E50-52 and B602 against methicillin resistant Staphylococcus aureus (MRSA) and other prominent nosocomial bacterial infections. methods: Several Russian hospitals were enlisted into the study from 2003 ...

  5. B-52B-008/DTV (Drop Test Vehicle) configuration 1 (with and without fins) flight test results - captive flight and drop test missions

    NASA Technical Reports Server (NTRS)

    Quade, D. A.

    1978-01-01

    The B-52B-008 drop test consisted of one takeoff roll to 60 KCAS, two captive flights to accomplish limited safety of flight flutter and structural demonstration testing, and seven drop test flights. Of the seven drop test missions, one flight was aborted due to the failure of the hook mechanism to release the drop test vehicle (DTV); but the other six flights successfully dropped the DTV.

  6. NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.

    PubMed

    Erlejman, Alejandra G; De Leo, Sonia A; Mazaira, Gisela I; Molinari, Alejandro M; Camisay, María Fernanda; Fontana, Vanina; Cox, Marc B; Piwien-Pilipuk, Graciela; Galigniana, Mario D

    2014-09-19

    Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to expand this model to other nuclear factors that are also subject to nuclear-cytoplasmic shuttling, we analyzed whether these immunophilins modulate NF-κB signaling. It is demonstrated that FKBP51 impairs both the nuclear translocation rate of NF-κB and its transcriptional activity. The inhibitory action of FKBP51 requires neither the peptidylprolyl-isomerase activity of the immunophilin nor its association with Hsp90. The TPR domain of FKBP51 is essential. On the other hand, FKBP52 favors the nuclear retention time of RelA, its association to a DNA consensus binding sequence, and NF-κB transcriptional activity, the latter effect being strongly dependent on the peptidylprolyl-isomerase activity and also on the TPR domain of FKBP52, but its interaction with Hsp90 is not required. In unstimulated cells, FKBP51 forms endogenous complexes with cytoplasmic RelA. Upon cell stimulation with phorbol ester, the NF-κB soluble complex exchanges FKBP51 for FKBP52, and the NF-κB biological effect is triggered. Importantly, FKBP52 is functionally recruited to the promoter region of NF-κB target genes, whereas FKBP51 is released. Competition assays demonstrated that both immunophilins antagonize one another, and binding assays with purified proteins suggest that the association of RelA and immunophilins could be direct. These observations suggest that the biological action of NF-κB in different cell types could be positively regulated by a high FKBP52/FKBP51 expression ratio by favoring NF-κB nuclear retention, recruitment to the promoter regions of target genes, and transcriptional activity. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. 12 CFR 223.52 - What transactions with affiliates or others must comply with section 23B's market terms requirement?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What transactions with affiliates or others must comply with section 23B's market terms requirement? 223.52 Section 223.52 Banks and Banking...) through (e) or (h) through (j) of § 223.42; (2) The sale of a security or other asset to an affiliate...

  8. Effect of Antifoam Agent on Oxidative Leaching of Hanford Tank Sludge Simulants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rapko, Brian M.; Jones, Susan A.; Lumetta, Gregg J.

    2010-02-26

    Oxidative leaching of simulant tank waste containing an antifoam agent (AFA) to reduce the chromium content of the sludge was tested using permanganate as the oxidant in 0.25 M NaOH solutions. AFA is added to the waste treatment process to prevent foaming. The AFA, Dow Corning Q2-3183A, is a surface-active polymer that consists of polypropylene glycol, polydimethylsiloxane, octylphenoxy polyethoxy ethanol, treated silica, and polyether polyol. Some of the Hanford Tank Waste Treatment and Immobilization Plant (WTP) waste slurries contain high concentrations of undissolved solids that would exhibit undesirable behavior without AFA addition. These tests were conducted to determine the effectmore » of the AFA on oxidative leaching of Cr(III) in waste by permanganate. It has not previously been determined what effect AFA has on the permanganate reaction. This study was conducted to determine the effect AFA has on the oxidation of the chromium, plus plutonium and other criticality-related elements, specifically Fe, Ni and Mn. During the oxidative leaching process, Mn is added as liquid permanganate solution and is converted to an insoluble solid that precipitates as MnO2 and becomes part of the solid waste. Caustic leaching was performed followed by an oxidative leach at either 25°C or 45°C. Samples of the leachate and solids were collected at each step of the process. Initially, Battelle-Pacific Northwest Division (PNWD) was contracted by Bechtel National, Inc. to perform these further scoping studies on oxidative alkaline leaching. The data obtained from the testing will be used by the WTP operations to develop procedures for permanganate dosing of Hanford tank sludge solids during oxidative leaching. Work was initially conducted under contract number 24590-101-TSA-W000-00004. In February 2007, the contract mechanism was switched to Pacific Northwest National Laboratory (PNNL) operating Contract DE-AC05-76RL01830. In summary, this report describes work focused on

  9. 40 CFR 52.1270 - Identification of plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... incorporated by reference from 40 CFR 52.21(b)(1)(i)(a) and (b)(1(iii)(t) APC-S-5. In addition, this EPA action... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Identification of plan. 52.1270 Section 52.1270 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  10. 40 CFR 52.1270 - Identification of plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... incorporated by reference from 40 CFR 52.21(b)(1)(i)(a) and (b)(1(iii)(t) APC-S-5. In addition, this EPA action... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Identification of plan. 52.1270 Section 52.1270 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  11. 42 CFR 52h.8 - What are the review criteria for grants?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... research, from a scientific or technical standpoint; (b) The adequacy of the approach and methodology... SCIENTIFIC PEER REVIEW OF RESEARCH GRANT APPLICATIONS AND RESEARCH AND DEVELOPMENT CONTRACT PROJECTS § 52h.8... review group shall assess the overall impact that the project could have on the research field involved...

  12. 9 CFR 52.4 - Presentation of claims.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE COOPERATIVE CONTROL AND ERADICATION OF LIVESTOCK OR POULTRY DISEASES SWINE DESTROYED BECAUSE OF PSEUDORABIES § 52.4 Presentation of claims. (a) When swine have been destroyed under § 52.2(a), any claim for... veterinarian in charge on a form furnished by APHIS. (b) When swine have been destroyed under § 52.2(b), any...

  13. 34 CFR 5.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... 552. (b) Department means the United States Department of Education. (c) Component means each separate... 34 Education 1 2014-07-01 2014-07-01 false Definitions. 5.2 Section 5.2 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC General Provisions § 5.2...

  14. Association of the HLA-B*52 allele with non-progression to AIDS in Brazilian HIV-1-infected individuals.

    PubMed

    Teixeira, S L M; de Sá, N B R; Campos, D P; Coelho, A B; Guimarães, M L; Leite, T C N F; Veloso, V G; Morgado, M G

    2014-04-01

    Several human leukocyte antigen (HLA) class I alleles are associated with the susceptibility to human immunodeficiency virus-1 (HIV-1) infection and/or AIDS progression. Of these, the HLA-B alleles are considered the strongest genetic determinant of disease outcome. We evaluated the influence of the HLA-B alleles on AIDS progression among HIV-1-positive individuals from Rio de Janeiro, Brazil, who were categorized as rapid progressors (RPs), typical progressors (TPs) or long-term non-progressors (LTNPs). In this study, significant differences in HLA-B allele frequencies were observed among the three progression groups for the B*48, B*49 and B*52 alleles. After controlling for other factors associated with AIDS progression, the presence of the B*52 allele was shown to be a significant protective factor (hazard ratio (HR) 0.49 (95% confidence interval (CI) 0.27-0.90) P<0.03). Although no direct association was observed between the presence of the B*27 or B*57 allele and the LTNP profile compared with the TP or RP groups, the adjusted model confirmed that these alleles are protective factors against AIDS progression (HR 0.62 (95% CI 0.38-0.99) P<0.05), as previously described. These data corroborate the existence of significant differences in HLA-B allele frequencies among the distinct AIDS progression profiles and further elucidate the role of HLA alleles in the outcome of HIV infections in diverse populations.

  15. 40 CFR 52.2230 - Attainment dates for national standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... 52.2230 Section 52.2230 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Tennessee § 52.2230...: Bristol and Kingsport nonattainment areas 1 d d c c b b d b. Campbell County nonattainment areas 1 d d c c...

  16. Drosophila Lin-52 Acts in Opposition to Repressive Components of the Myb-MuvB/dREAM Complex

    PubMed Central

    Lewis, Peter W.; Sahoo, Debashis; Geng, Cuiyun; Bell, Maren

    2012-01-01

    The Drosophila melanogaster Myb-MuvB/dREAM complex (MMB/dREAM) participates in both the activation and repression of developmentally regulated genes and origins of DNA replication. Mutants in MMB subunits exhibit diverse phenotypes, including lethality, eye defects, reduced fecundity, and sterility. Here, we used P-element excision to generate mutations in lin-52, which encodes the smallest subunit of the MMB/dREAM complex. lin-52 is required for viability, as null mutants die prior to pupariation. The generation of somatic and germ line mutant clones indicates that lin-52 is required for adult eye development and for early embryogenesis via maternal effects. Interestingly, the maternal-effect embryonic lethality, larval lethality, and adult eye defects could be suppressed by mutations in other subunits of the MMB/dREAM complex. These results suggest that a partial MMB/dREAM complex is responsible for the lethality and eye defects of lin-52 mutants. Furthermore, these findings support a model in which the Lin-52 and Myb proteins counteract the repressive activities of the other members of the MMB/dREAM complex at specific genomic loci in a developmentally controlled manner. PMID:22688510

  17. 36 CFR 261.52 - Fire.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Fire. 261.52 Section 261.52... in Areas Designated by Order § 261.52 Fire. When provided by an order, the following are prohibited: (a) Building, maintaining, attending or using a fire, campfire, or stove fire. (b) Using an explosive...

  18. 36 CFR 261.52 - Fire.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Fire. 261.52 Section 261.52... in Areas Designated by Order § 261.52 Fire. When provided by an order, the following are prohibited: (a) Building, maintaining, attending or using a fire, campfire, or stove fire. (b) Using an explosive...

  19. 36 CFR 261.52 - Fire.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Fire. 261.52 Section 261.52... in Areas Designated by Order § 261.52 Fire. When provided by an order, the following are prohibited: (a) Building, maintaining, attending or using a fire, campfire, or stove fire. (b) Using an explosive...

  20. 36 CFR 261.52 - Fire.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Fire. 261.52 Section 261.52... in Areas Designated by Order § 261.52 Fire. When provided by an order, the following are prohibited: (a) Building, maintaining, attending or using a fire, campfire, or stove fire. (b) Using an explosive...

  1. 40 CFR 52.742 - Incorporation by reference.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Water-Reducible Paints by Direct Injection into a Gas Chromatograph, for § 52.741(a)(4)(i)(B)(3)(iii... Chromatograph, for § 52.741(a)(4)(i)(B)(3)(v). (6) ASTM D2697-86, Standard Test Method for Volume Nonvolatile... Liquids by Isoteniscope, for § 52.741(a)(3), (a)(8)(ii), (a)(9)(iii), and (a)(10)(iii). (11) ASTM D323-82...

  2. NASA's B-52 mother ship carries the X-43A and its booster rocket on a captive carry flight Jan. 26, 2004

    NASA Image and Video Library

    2004-01-26

    NASA's historic B-52 mother ship carried the X-43A and its Pegasus booster rocket on a captive carry flight from Edwards Air Force Base Jan. 26, 2004. The X-43A and its booster remained mated to the B-52 throughout the two-hour flight, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

  3. Impact of IL1B gene polymorphisms and interleukin 1B levels on susceptibility to spontaneous preterm birth.

    PubMed

    Langmia, Immaculate M; Apalasamy, Yamunah D; Omar, Siti Z; Mohamed, Zahurin

    2016-11-01

    Genetic factors influence susceptibility to preterm birth (PTB) and the immune pathway of PTB that involves the production of cytokines such as interleukins has been implicated in PTB disease. The aim of this study is to investigate the association of interleukin 1β (IL1B) gene polymorphisms and IL1B levels with spontaneous PTB. Peripheral maternal blood from 495 women was used for extraction of DNA and genotyping was carried out using the Sequenom MassARRAY platform. Maternal plasma was used to measure IL1B levels. There was no significant association between the allelic and genotype distribution of IL1B single nucleotide polymorphism (SNP) (rs1143634, rs1143627, rs16944) and the risk of PTB among Malaysian Malay women (rs1143634, P=0.722; rs1143627, P=0.543; rs16944, P=0.615). However, IL1B levels were significantly different between women who delivered preterm compared with those who delivered at term (P=0.030); high mean levels were observed among Malay women who delivered at preterm (mean=32.52) compared with term (mean=21.68). IL1B SNPs were not associated with IL1B plasma levels. This study indicates a significant association between IL1B levels and reduced risk of PTB among the Malaysian Malay women. This study shows the impact of IL1B levels on susceptibility to PTB disease; however, the high levels of IL1B observed among women in the preterm group are not associated with IL1B SNPs investigated in this study; IL1B high levels may be because of other factors not explored in this study and therefore warrant further investigation.

  4. 40 CFR 52.626 - Compliance schedules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Compliance schedules. 52.626 Section 52.626 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Hawaii § 52.626 Compliance schedules. (a) [Reserved] (b...

  5. he second X-43A and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean on March 27, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif. Minutes later the X-43A separated from the Pegasus booster and accelerated to its intended speed of Mach 7.

  6. 40 CFR 52.1033 - Visibility protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... visibility in mandatory class I Federal areas. (b) [Reserved] (c) Long-term strategy. The provisions of § 52... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Visibility protection. 52.1033 Section 52.1033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  7. 40 CFR 52.1033 - Visibility protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... visibility in mandatory class I Federal areas. (b) [Reserved] (c) Long-term strategy. The provisions of § 52... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Visibility protection. 52.1033 Section 52.1033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  8. 40 CFR 52.1033 - Visibility protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... visibility in mandatory class I Federal areas. (b) [Reserved] (c) Long-term strategy. The provisions of § 52... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Visibility protection. 52.1033 Section 52.1033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  9. 40 CFR 52.1033 - Visibility protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... visibility in mandatory class I Federal areas. (b) [Reserved] (c) Long-term strategy. The provisions of § 52... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Visibility protection. 52.1033 Section 52.1033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  10. X-38 flies free from NASA's B-52 mothership, July 10, 2001

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The second free-flight test of an evolving series of X-38 prototypes took place July 10, 2001 when the X-38 was released from NASA's B-52 mothership over the Edwards Air Force Base range in California's Mojave Desert. Shortly after the photo was taken, a sequenced deployment of a drogue parachute followed by a large parafoil fabric wing slowed the X-38 to enable it to land safely on Rogers Dry Lake at Edwards. NASA engineers from the Dryden Flight Research Center at Edwards, and the Johnson Space Center, Houston, Texas, are developing a 'lifeboat' for the International Space Station based on X-38 research.

  11. X-38 flies free from NASA's B-52 mothership, July 10, 2001

    NASA Image and Video Library

    2001-07-10

    The second free-flight test of an evolving series of X-38 prototypes took place July 10, 2001 when the X-38 was released from NASA's B-52 mothership over the Edwards Air Force Base range in California's Mojave Desert. Shortly after the photo was taken, a sequenced deployment of a drogue parachute followed by a large parafoil fabric wing slowed the X-38 to enable it to land safely on Rogers Dry Lake at Edwards. NASA engineers from the Dryden Flight Research Center at Edwards, and the Johnson Space Center, Houston, Texas, are developing a "lifeboat" for the International Space Station based on X-38 research.

  12. Integration of the B-52G Offensive Avionics System (OAS) with the Global Positioning System (GPS)

    NASA Astrophysics Data System (ADS)

    Foote, A. L.; Pluntze, S. C.

    Integration of the B-52G OAS with the GPS has been accomplished by modification of existing OAS software. GPS derived position and velocity data are used to enhance the quality of the OAS inertial and dead reckoning navigation systems. The engineering design and the software development process used to implement this design are presented.

  13. 28 CFR 91.52 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Definitions. 91.52 Section 91.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review... on Environmental Quality in its Regulations for Implementing the Procedural Provisions of the...

  14. 28 CFR 91.52 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Definitions. 91.52 Section 91.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review... on Environmental Quality in its Regulations for Implementing the Procedural Provisions of the...

  15. 28 CFR 91.52 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Definitions. 91.52 Section 91.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review... on Environmental Quality in its Regulations for Implementing the Procedural Provisions of the...

  16. 28 CFR 91.52 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Definitions. 91.52 Section 91.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review... on Environmental Quality in its Regulations for Implementing the Procedural Provisions of the...

  17. 28 CFR 91.52 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Definitions. 91.52 Section 91.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GRANTS FOR CORRECTIONAL FACILITIES Environmental Impact Review... on Environmental Quality in its Regulations for Implementing the Procedural Provisions of the...

  18. Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.

    PubMed

    Yonezawa, Atsushi; Inui, Ken-ichi

    2013-01-01

    Riboflavin, a water-soluble vitamin also known as vitamin B2, is essential for normal cellular functions. Riboflavin transporters play important roles in its homeostasis. Recently, three novel riboflavin transporters were identified, and designated as RFT1, RFT2 and RFT3. Because the RFTs did not show similarity to other SLC transporters, and RFT1 and RFT3 are similar in sequence and function, they were assigned into a new SLC family, SLC52. Subsequently, RFT1/GPR172B, RFT3/GPR172A and RFT2/C20orf54 were renamed as RFVT1/SLC52A1, RFVT2/SLC52A2 and RFVT3/SLC52A3, respectively. In this review, we summarize recent findings on the cloning, nomenclature, functional characterization and genetic diseases of RFVT1/SLC52A1, RFVT2/SLC52A2 and RFVT3/SLC52A3. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. 40 CFR 52.1235 - Regional haze.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Regional haze. 52.1235 Section 52.1235 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1235 Regional haze. (a) [Reserved] (b)(1) NO X...

  20. 40 CFR 52.1235 - Regional haze.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Regional haze. 52.1235 Section 52.1235 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota § 52.1235 Regional haze. (a) [Reserved] (b)(1) NO X...

  1. 40 CFR 52.61 - Visibility protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Visibility protection. 52.61 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.61 Visibility protection. (a) The... procedures for protection of visibility in mandatory Class I Federal areas. (b) Long-term strategy. The...

  2. 40 CFR 52.61 - Visibility protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Visibility protection. 52.61 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.61 Visibility protection. (a) The... procedures for protection of visibility in mandatory Class I Federal areas. (b) Long-term strategy. The...

  3. 10 CFR 52.4 - Deliberate misconduct.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Deliberate misconduct. 52.4 Section 52.4 Energy NUCLEAR... Provisions § 52.4 Deliberate misconduct. (a) Applicability. This section applies to any: (1) Licensee; (2..., or a standard design approval. (b) Definitions. For purposes of this section: Deliberate misconduct...

  4. 10 CFR 52.4 - Deliberate misconduct.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Deliberate misconduct. 52.4 Section 52.4 Energy NUCLEAR... Provisions § 52.4 Deliberate misconduct. (a) Applicability. This section applies to any: (1) Licensee; (2..., or a standard design approval. (b) Definitions. For purposes of this section: Deliberate misconduct...

  5. 10 CFR 52.4 - Deliberate misconduct.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Deliberate misconduct. 52.4 Section 52.4 Energy NUCLEAR... Provisions § 52.4 Deliberate misconduct. (a) Applicability. This section applies to any: (1) Licensee; (2..., or a standard design approval. (b) Definitions. For purposes of this section: Deliberate misconduct...

  6. 10 CFR 52.4 - Deliberate misconduct.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Deliberate misconduct. 52.4 Section 52.4 Energy NUCLEAR... Provisions § 52.4 Deliberate misconduct. (a) Applicability. This section applies to any: (1) Licensee; (2..., or a standard design approval. (b) Definitions. For purposes of this section: Deliberate misconduct...

  7. 10 CFR 52.4 - Deliberate misconduct.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Deliberate misconduct. 52.4 Section 52.4 Energy NUCLEAR... Provisions § 52.4 Deliberate misconduct. (a) Applicability. This section applies to any: (1) Licensee; (2..., or a standard design approval. (b) Definitions. For purposes of this section: Deliberate misconduct...

  8. 22 CFR 40.52 - Unqualified physicians.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Unqualified physicians. 40.52 Section 40.52 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH NONIMMIGRANTS AND IMMIGRANTS... Immigrants § 40.52 Unqualified physicians. INA 212(a)(5)(B) applies only to immigrant aliens described in INA...

  9. Observational constraints for the circumstellar disk of the B[e] star CPD-52 9243

    NASA Astrophysics Data System (ADS)

    Cidale, L. S.; Borges Fernandes, M.; Andruchow, I.; Arias, M. L.; Kraus, M.; Chesneau, O.; Kanaan, S.; Curé, M.; de Wit, W. J.; Muratore, M. F.

    2012-12-01

    Context. The formation and evolution of gas and dust environments around B[e] supergiants are still open issues. Aims: We intend to study the geometry, kinematics and physical structure of the circumstellar environment (CE) of the B[e] supergiant CPD-52 9243 to provide further insights into the underlying mechanism causing the B[e] phenomenon. Methods: The influence of the different physical mechanisms acting on the CE (radiation pressure, rotation, bi-stability or tidal forces) is somehow reflected in the shape and kinematic properties of the gas and dust regions (flaring, Keplerian, accretion or outflowing disks). To investigate these processes we mainly used quasi-simultaneous observations taken with high spatial resolution optical long-baseline interferometry (VLTI/MIDI), near-IR spectroscopy of CO bandhead features (Gemini/Phoenix and VLT/CRIRES) and optical spectra (CASLEO/REOSC). Results: High angular resolution interferometric measurements obtained with VLTI/MIDI provide strong support for the presence of a dusty disk(ring)-like structure around CPD-52 9243, with an upper limit for its inner edge of ~8 mas (~27.5 AU, considering a distance of 3.44 kpc to the star). The disk has an inclination angle with respect to the line of sight of 46 ± 7°. The study of CO first overtone bandhead evidences a disk structure in Keplerian rotation. The optical spectrum indicates a rapid outflow in the polar direction. Conclusions: The IR emission (CO and warm dust) indicates Keplerian rotation in a circumstellar disk while the optical line transitions of various species are consistent with a polar wind. Both structures appear simultaneously and provide further evidence for the proposed paradigms of the mass-loss in supergiant B[e] stars. The presence of a detached cold CO ring around CPD-52 9243 could be due to a truncation of the inner disk caused by a companion, located possibly interior to the disk rim, clearing the center of the system. More spectroscopic and

  10. 16 CFR 1101.52 - Procedure for retraction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Procedure for retraction. 1101.52 Section... INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.52 Procedure for retraction. (a) Initiative. The Commission may retract information under section 6(b)(7) on the...

  11. 16 CFR 1101.52 - Procedure for retraction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Procedure for retraction. 1101.52 Section... INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.52 Procedure for retraction. (a) Initiative. The Commission may retract information under section 6(b)(7) on the...

  12. 16 CFR 1101.52 - Procedure for retraction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Procedure for retraction. 1101.52 Section... INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.52 Procedure for retraction. (a) Initiative. The Commission may retract information under section 6(b)(7) on the...

  13. 16 CFR 1101.52 - Procedure for retraction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Procedure for retraction. 1101.52 Section... INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.52 Procedure for retraction. (a) Initiative. The Commission may retract information under section 6(b)(7) on the...

  14. 40 CFR 52.775 - Legal authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Legal authority. 52.775 Section 52.775... PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.775 Legal authority. (a) The requirements of § 51.232(b) of this chapter are not met since the following deficiencies exist in the local agency legal authority: (1...

  15. 40 CFR 52.775 - Legal authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Legal authority. 52.775 Section 52.775... PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.775 Legal authority. (a) The requirements of § 51.232(b) of this chapter are not met since the following deficiencies exist in the local agency legal authority: (1...

  16. 40 CFR 52.775 - Legal authority.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Legal authority. 52.775 Section 52.775... PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.775 Legal authority. (a) The requirements of § 51.232(b) of this chapter are not met since the following deficiencies exist in the local agency legal authority: (1...

  17. 40 CFR 52.775 - Legal authority.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Legal authority. 52.775 Section 52.775... PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.775 Legal authority. (a) The requirements of § 51.232(b) of this chapter are not met since the following deficiencies exist in the local agency legal authority: (1...

  18. 40 CFR 52.775 - Legal authority.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Legal authority. 52.775 Section 52.775... PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.775 Legal authority. (a) The requirements of § 51.232(b) of this chapter are not met since the following deficiencies exist in the local agency legal authority: (1...

  19. Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses

    PubMed Central

    Murakoshi, Hayato; Koyanagi, Madoka; Chikata, Takayuki; Rahman, Mohammad Arif; Kuse, Nozomi; Sakai, Keiko; Gatanaga, Hiroyuki; Oka, Shinichi

    2016-01-01

    ABSTRACT HLA-B*52:01-C*12:02, which is the most abundant haplotype in Japan, has a protective effect on disease progression in HIV-1-infected Japanese individuals, whereas HLA-B*57 and -B*27 protective alleles are very rare in Japan. A previous study on HLA-associated polymorphisms demonstrated that the number of HLA-B*52:01-associated mutations at four Pol positions was inversely correlated with plasma viral load (pVL) in HLA-B*52:01-negative individuals, suggesting that the transmission of HIV-1 with these mutations could modulate the pVL in the population. However, it remains unknown whether these mutations were selected by HLA-B*52:01-restricted CTLs and also reduced viral fitness. In this study, we identified two HLA-B*52:01-restricted and one HLA-C*12:02-restricted novel cytotoxic T-lymphocyte (CTL) epitopes in Pol. Analysis using CTLs specific for these three epitopes demonstrated that these CTLs failed to recognize mutant epitopes or more weakly recognized cells infected with mutant viruses than wild-type virus, supporting the idea that these mutations were selected by the HLA-B*52:01- or HLA-C*12:02-restricted T cells. We further showed that these mutations reduced viral fitness, although the effect of each mutation was weak. The present study demonstrated that the accumulation of these Pol mutations selected by HLA-B*52:01- or HLA-C*12:02-restricted CTLs impaired viral replication capacity and thus reduced the pVL. The fitness cost imposed by the mutations partially accounted for the effect of the HLA-B*52:01-C*12:02 haplotype on clinical outcome, together with the effect of HLA-B*52:01-restricted CTLs on viral replication, which had been previously demonstrated. IMPORTANCE Numerous population-based studies identified HLA-associated HIV-1 mutations to predict HIV-1 escape mutations from cytotoxic T lymphocytes (CTLs). However, the majority of these HLA-associated mutations have not been identified as CTL escape mutations. Our previous population

  20. Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.

    PubMed

    Murakoshi, Hayato; Koyanagi, Madoka; Chikata, Takayuki; Rahman, Mohammad Arif; Kuse, Nozomi; Sakai, Keiko; Gatanaga, Hiroyuki; Oka, Shinichi; Takiguchi, Masafumi

    2017-02-15

    HLA-B*52:01-C*12:02, which is the most abundant haplotype in Japan, has a protective effect on disease progression in HIV-1-infected Japanese individuals, whereas HLA-B*57 and -B*27 protective alleles are very rare in Japan. A previous study on HLA-associated polymorphisms demonstrated that the number of HLA-B*52:01-associated mutations at four Pol positions was inversely correlated with plasma viral load (pVL) in HLA-B*52:01-negative individuals, suggesting that the transmission of HIV-1 with these mutations could modulate the pVL in the population. However, it remains unknown whether these mutations were selected by HLA-B*52:01-restricted CTLs and also reduced viral fitness. In this study, we identified two HLA-B*52:01-restricted and one HLA-C*12:02-restricted novel cytotoxic T-lymphocyte (CTL) epitopes in Pol. Analysis using CTLs specific for these three epitopes demonstrated that these CTLs failed to recognize mutant epitopes or more weakly recognized cells infected with mutant viruses than wild-type virus, supporting the idea that these mutations were selected by the HLA-B*52:01- or HLA-C*12:02-restricted T cells. We further showed that these mutations reduced viral fitness, although the effect of each mutation was weak. The present study demonstrated that the accumulation of these Pol mutations selected by HLA-B*52:01- or HLA-C*12:02-restricted CTLs impaired viral replication capacity and thus reduced the pVL. The fitness cost imposed by the mutations partially accounted for the effect of the HLA-B*52:01-C*12:02 haplotype on clinical outcome, together with the effect of HLA-B*52:01-restricted CTLs on viral replication, which had been previously demonstrated. Numerous population-based studies identified HLA-associated HIV-1 mutations to predict HIV-1 escape mutations from cytotoxic T lymphocytes (CTLs). However, the majority of these HLA-associated mutations have not been identified as CTL escape mutations. Our previous population-based study showed that five

  1. 40 CFR 52.1270 - Identification of plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Classification System (NAICS) codes 325193 or 312140,” APC-S-5 incorporated by reference from 40 CFR 52.21(b)(1... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Identification of plan. 52.1270 Section 52.1270 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED...

  2. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Program reporting. 233.52 Section 233.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  3. 40 CFR 233.52 - Program reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Program reporting. 233.52 Section 233.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING 404 STATE... cumulative impacts of the State's permit program on the integrity of the State regulated waters...

  4. A modified Pegasus rocket drops steadily away after release from NASA's B-52B, before accelerating the X-43A over the Pacific Ocean on March 27, 2004

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket drop away from NASA's B-52B launch aircraft over the Pacific Ocean on March 27, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif. Moments later the Pegasus booster ignited to accelerate the X-43A to its intended speed of Mach 7.

  5. 40 CFR 230.52 - Water-related recreation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Water-related recreation. 230.52 Section 230.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING SECTION 404(b)(1) GUIDELINES FOR SPECIFICATION OF DISPOSAL SITES FOR DREDGED OR FILL MATERIAL Potential Effects on Human Use Characteristics § 230.52...

  6. Development and Testing of a Drogue Parachute System for X-37 ALTV/B-52H Separation

    NASA Technical Reports Server (NTRS)

    Whitmore, Stephen A.; Cobleigh, Brent R.; Jacobson, Steven R.; Jensen, Steven C.; Hennings, Elsa J.

    2004-01-01

    Multiple scenarios were identified in which the X-37 approach and landing test vehicle (ALTV) catastrophically recontacts the B-52H carrier aircraft after separation. The most cost-effective recontact risk mitigation is the prelaunch deployment of a drogue parachute that is released after the X-37 ALTV has safely cleared the B-52H. After release, a fully-inflated drogue parachute takes 30 min to reach ground and results in a large footprint that excessively restricts the days available for flight. To reduce the footprint, a passive collapse mechanism consisting of an elastic reefing line attached to the parachute skirt was developed. At flight loads the elastic is stretched, allowing full parachute inflation. After release, drag loads drop dramatically and the elastic line contracts, reducing the frontal drag area. A 50-percent drag reduction results in an approximately 75-percent ground footprint reduction. Eleven individual parachute designs were evaluated at flight load dynamic pressures in the High Velocity Airflow System (HIVAS) at the Naval Air Warfare Center (NAWC), China Lake, California. Various options for the elastic reefing system were also evaluated at HIVAS. Two best parachute designs were selected from HIVAS to be carried forward to flight test. Detailed HIVAS test results are presented in this report.

  7. Development and Testing of a Drogue Parachute System for X-37 ALTV/B-52H Separation

    NASA Technical Reports Server (NTRS)

    Whitmore, Stephen A.; Cobleigh, Brent R.; Jacobson, Steven R.; Jensen, Steven C.; Hennings, Elsa J.

    2004-01-01

    Multiple scenarios were identified in which the X-37 approach and landing test vehicle (ALTV) catastrophically recontacts the B-52H carrier aircraft after separation. The most cost-effective recontact risk mitigation is the prelaunch deployment of a drogue parachute that is released after the X-37 ALTV has safely cleared the B-52H. After release, a fully-inflated drogue parachute takes 30 min to reach ground and results in a large footprint that excessively restricts the days available for flight. To reduce the footprint, a passive collapse mechanism consisting of an elastic reefing line attached to the parachute skirt was developed. At flight loads the elastic is stretched, allowing full parachute inflation. After release, drag loads drop dramatically and the elastic line contracts, reducing the frontal drag area. A 50 percent drag reduction results in an approximately 75 percent ground footprint reduction. Eleven individual parachute designs were evaluated at flight load dynamic pressures in the High Velocity Airflow System (HIVAS) at the Naval Air Warfare Center (NAWC), China Lake, California. Various options for the elastic reefing system were also evaluated at HIVAS. Two best parachute designs were selected from HIVAS to be carried forward to flight test. Detailed HIVAS test results are presented in this report.

  8. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  9. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  10. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  11. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  12. 46 CFR 52.01-10 - Automatic controls.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Automatic controls. 52.01-10 Section 52.01-10 Shipping... Requirements § 52.01-10 Automatic controls. (a) Each main boiler must meet the special requirements for automatic safety controls in § 62.35-20(a)(1) of this chapter. (b) Each automatically controlled auxiliary...

  13. 6 CFR 9.52 - Inspector General report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Inspector General report. 9.52 Section 9.52... Agency Reports § 9.52 Inspector General report. (a) The Inspector General, or other official as specified in paragraph (b) of this section, of each agency shall prepare and submit to Congress each year an...

  14. 6 CFR 9.52 - Inspector General report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Inspector General report. 9.52 Section 9.52... Agency Reports § 9.52 Inspector General report. (a) The Inspector General, or other official as specified in paragraph (b) of this section, of each agency shall prepare and submit to Congress each year an...

  15. 6 CFR 9.52 - Inspector General report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Inspector General report. 9.52 Section 9.52... Agency Reports § 9.52 Inspector General report. (a) The Inspector General, or other official as specified in paragraph (b) of this section, of each agency shall prepare and submit to Congress each year an...

  16. 6 CFR 9.52 - Inspector General report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Inspector General report. 9.52 Section 9.52... Agency Reports § 9.52 Inspector General report. (a) The Inspector General, or other official as specified in paragraph (b) of this section, of each agency shall prepare and submit to Congress each year an...

  17. 6 CFR 9.52 - Inspector General report.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Inspector General report. 9.52 Section 9.52... Agency Reports § 9.52 Inspector General report. (a) The Inspector General, or other official as specified in paragraph (b) of this section, of each agency shall prepare and submit to Congress each year an...

  18. 40 CFR 52.2382 - Rules and regulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pollution notification requirements. (5) Conflict of interest requirements. (b) Regulation for visibility monitoring and new source review. The provisions of §§ 52.26 and 52.27 are hereby incorporated and made a...

  19. 16 CFR § 1101.52 - Procedure for retraction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Procedure for retraction. § 1101.52 Section... REGULATIONS INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.52 Procedure for retraction. (a) Initiative. The Commission may retract information under section 6(b)(7) on...

  20. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Failed lots/rework procedure. 983.52 Section 983.52..., ARIZONA, AND NEW MEXICO Regulations § 983.52 Failed lots/rework procedure. (a) Substandard pistachios... committee may establish, with the Secretary's approval, appropriate rework procedures. (b) Failed lot...

  1. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Failed lots/rework procedure. 983.52 Section 983.52..., ARIZONA, AND NEW MEXICO Regulations § 983.52 Failed lots/rework procedure. (a) Substandard pistachios... committee may establish, with the Secretary's approval, appropriate rework procedures. (b) Failed lot...

  2. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Failed lots/rework procedure. 983.52 Section 983.52..., ARIZONA, AND NEW MEXICO Regulations § 983.52 Failed lots/rework procedure. (a) Substandard pistachios... committee may establish, with the Secretary's approval, appropriate rework procedures. (b) Failed lot...

  3. A modified Pegasus rocket drops away after release from NASA's B-52B before accelerating the X-43A over a Pacific Ocean test range on Nov. 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket drop away from NASA's B-52B launch aircraft over the Pacific Ocean on November 16, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, California. Moments later the Pegasus booster ignited to accelerate the X-43A to its intended speed of Mach 10.

  4. 40 CFR 52.2773 - EPA-approved Virgin Islands regulations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... at 40 CFR 52.21(b)(20). Section 204-21, “Regulations to Control Open Burning” 1/15/87 .....do Section.... 52.2773 Section 52.2773 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Virgin Islands § 52.2773...

  5. 40 CFR 52.2773 - EPA-approved Virgin Islands regulations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... at 40 CFR 52.21(b)(20). Section 204-21, “Regulations to Control Open Burning” 1/15/87 .....do Section.... 52.2773 Section 52.2773 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Virgin Islands § 52.2773...

  6. 40 CFR 52.2773 - EPA-approved Virgin Islands regulations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... at 40 CFR 52.21(b)(20). Section 204-21, “Regulations to Control Open Burning” 1/15/87 .....do Section.... 52.2773 Section 52.2773 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Virgin Islands § 52.2773...

  7. 40 CFR 52.2773 - EPA-approved Virgin Islands regulations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... at 40 CFR 52.21(b)(20). Section 204-21, “Regulations to Control Open Burning” 1/15/87 .....do Section.... 52.2773 Section 52.2773 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Virgin Islands § 52.2773...

  8. Downregulation of active IKKβ by Ro52-mediated autophagy

    PubMed Central

    Niida, Motoko; Tanaka, Makoto; Kamitani, Tetsu

    2010-01-01

    Upon activation, NF-κB translocates into the nucleus and initiates many biological events. This NF-κB signaling is mainly induced by the protein kinase IKKβ. Early in this signaling pathway, IKKβ is phosphorylated for activation by several factors, such as pro-inflammatory cytokines and the Tax oncoprotein of human T-cell leukemia virus type 1 (HTLV-1). In cells expressing Tax protein, IKKβ is persistently phosphorylated, which chronically activates NF-κB signaling. But the active IKKβ is conjugated with a monoubiquitin by the E3 ubiquitin ligase Ro52, and the IKKβ-induced NF-κB signaling is downregulated. However, the mechanism of the downregulation has been unknown. Here, we show that Ro52-mediated monoubiquitination is involved in the subcellular translocation of active IKKβ to autophagosomes. Furthermore, using reporter assays, we show that Ro52 suppresses IKKβ-induced NF-κB signaling and that this suppression is blocked by an autophagy inhibitor. These results suggest that Ro52-mediated monoubiquitination plays a critical role in the downregulation of active IKKβ through autophagy. PMID:20627395

  9. 38 CFR 52.170 - Dental services.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Dental services. 52.170... FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.170 Dental services. (a) Program... (2) By arranging for transportation to and from the dental services. (b) Program management must...

  10. 38 CFR 52.170 - Dental services.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Dental services. 52.170... FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.170 Dental services. (a) Program... (2) By arranging for transportation to and from the dental services. (b) Program management must...

  11. 38 CFR 52.170 - Dental services.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Dental services. 52.170... FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.170 Dental services. (a) Program... (2) By arranging for transportation to and from the dental services. (b) Program management must...

  12. 38 CFR 52.170 - Dental services.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Dental services. 52.170... FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.170 Dental services. (a) Program... (2) By arranging for transportation to and from the dental services. (b) Program management must...

  13. 38 CFR 52.170 - Dental services.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Dental services. 52.170... FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Standards § 52.170 Dental services. (a) Program... (2) By arranging for transportation to and from the dental services. (b) Program management must...

  14. NASA's B-52B launch aircraft cruises to a test range over the Pacific Ocean carrying the second X-43A vehicle attached to a Pegasus rocket on March 27, 2004

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft, attached to a modified Pegasus booster rocket and followed by a chase F-18, was taken to launch altitude by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif., on March 27, 2004. About an hour later the Pegasus booster was released from the B-52 to accelerate the X-43A to its intended speed of Mach 7. In a combined research effort involving Dryden, Langley, and several industry partners, NASA demonstrated the value of its X-43A hypersonic research aircraft, as it became the first air-breathing, unpiloted, scramjet-powered plane to fly freely by itself. The March 27 flight, originating from NASA's Dryden Flight Research Center, began with the Agency's B-52B launch aircraft carrying the X-43A out to the test range over the Pacific Ocean off the California coast. The X-43A was boosted up to its test altitude of about 95,000 feet, where it separated from its modified Pegasus booster and flew freely under its own power. Two very significant aviation milestones occurred during this test flight: first, controlled accelerating flight at Mach 7 under scramjet power, and second, the successful stage separation at high dynamic pressure of two non-axisymmetric vehicles. To top it all off, the flight resulted in the setting of a new aeronautical speed record. The X-43A reached a speed of over Mach 7, or about 5,000 miles per hour faster than any known aircraft powered by an air-breathing engine has ever flown.

  15. 10 CFR 52.11 - Information collection requirements: OMB approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... A, B, C, D, and N of part 52. ... 10 Energy 2 2010-01-01 2010-01-01 false Information collection requirements: OMB approval. 52.11 Section 52.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR...

  16. 10 CFR 52.11 - Information collection requirements: OMB approval.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... A, B, C, D, and N of part 52. ... 10 Energy 2 2012-01-01 2012-01-01 false Information collection requirements: OMB approval. 52.11 Section 52.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR...

  17. 26 CFR 1.52-3 - Limitations with respect to certain persons.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... control, under § 1.52-1 (a) and (b). (b) Regulated investment companies and real estate investment trusts... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Limitations with respect to certain persons. 1.52-3 Section 1.52-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY INCOME TAX...

  18. A modified Pegasus rocket ignites moments after release from the B-52B, beginning the acceleration of the X-43A over the Pacific Ocean on Nov. 16, 2004

    NASA Image and Video Library

    2004-11-16

    The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean on November 16, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, California. Minutes later the X-43A separated from the Pegasus booster and accelerated to its intended speed of Mach 10.

  19. 10 CFR Appendix C to Part 52 - Design Certification Rule for the AP600 Design

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... design, in accordance with 10 CFR part 52, subpart B. The applicant for certification of the AP600 design....55(b) and 52.57(b). This appendix remains valid for an applicant or licensee who references this.... Exemptions from Tier 1 information are governed by the requirements in 10 CFR 52.63(b)(1) and 52.98(f). The...

  20. Analysis and testing of stability augmentation systems. [for supersonic transport aircraft wing and B-52 aircraft control system

    NASA Technical Reports Server (NTRS)

    Sevart, F. D.; Patel, S. M.; Wattman, W. J.

    1972-01-01

    Testing and evaluation of stability augmentation systems for aircraft flight control were conducted. The flutter suppression system analysis of a scale supersonic transport wing model is described. Mechanization of the flutter suppression system is reported. The ride control synthesis for the B-52 aeroelastic model is discussed. Model analyses were conducted using equations of motion generated from generalized mass and stiffness data.

  1. Haemophilus influenzae type b conjugate vaccine impact against purulent meningitis in Rwanda.

    PubMed

    Muganga, Narcisse; Uwimana, Jeannine; Fidele, Ngabo; Gahimbare, Laetitia; Gessner, Bradford D; Mueller, Judith E; Mhlanga, Bekithemba R; Katsande, Reggis; Herbinger, Karl-Heinz; Rugambwa, Celse

    2007-09-28

    Rwanda introduced Haemophilus influenzae type b (Hib) conjugate vaccine in January 2002 and simultaneously implemented pediatric bacterial meningitis surveillance at a major referral hospital in the capital Kigali. We reviewed clinical and laboratory information collected during January 2002 to June 2006. Due to a variety of laboratory limitations, only eight confirmed Hib cases were identified, all before 2004. However, the proportion of cerebrospinal fluid with purulence decreased from 26.0% during 2002, to 15.9% during 2003, 9.7% during 2004 and 8.4% in 2005 (p<0.001). Vaccine effectiveness of two or three doses of Hib vaccine against purulent meningitis was 52% (95% confidence interval, 5-75%). In an African setting with few resources and in which few confirmed Hib meningitis cases were identified, Hib vaccine impact nevertheless could be demonstrated against the outcome of purulent meningitis and was found to be high.

  2. Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

    PubMed Central

    Tan, H-Y; Wang, N; Man, K; Tsao, S-W; Che, C-M; Feng, Y

    2015-01-01

    The plasticity of tumour-associated macrophages (TAMs) has implicated an influential role in hepatocellular carcinoma (HCC). Repolarisation of TAM towards M1 phenotype characterises an immune-competent microenvironment that favours tumour regression. To investigate the role and mechanism of TAM repolarisation in suppression of HCC by a natural compound baicalin, Orthotopic HCC implantation model was used to investigate the effect of baicalin on HCC; liposome-clodronate was introduced to suppress macrophage populations in mice; bone marrow-derived monocytes (BMDMs) were induced to unpolarised, M1-like, M2-like macrophages and TAM using different conditioned medium. We observed that oral administration of baicalin (50 mg/kg) completely blocked orthotopic growth of implanted HCC. Suppression of HCC by baicalin was diminished when mice macrophage was removed by clodronate treatment. Baicalin induced repolarisation of TAM to M1-like phenotype without specific toxicity to either phenotype of macrophages. Baicalin initiated TAM reprogramming to M1-like macrophage, and promoted pro-inflammatory cytokines production. Co-culturing of HCC cells with baicalin-treated TAMs resulted in reduced proliferation and motility in HCC. Baicalin had minimal effect on derivation of macrophage polarisation factors by HCC cells, while directly induced repolarisation of TAM and M2-like macrophage. This effect was associated with elevated autophagy, and transcriptional activation of RelB/p52 pathway. Suppression of autophagy or RelB abolished skewing of baicalin-treated TAM. Autophagic degradation of TRAF2 in baicalin-treated TAM might be responsible for RelB/p52 activation. Our findings unveil the essential role of TAM repolarisation in suppressive effect of baicalin on HCC, which requires autophagy-associated activation of RelB/p52. PMID:26492375

  3. 40 CFR 52.2922 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2922 Section 52.2922 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Northern Mariana Islands § 52.2922 Significant deterioration of air quality. (a) The requirements of... procedures for preventing the significant deterioration of air quality. (b) Regulations for preventing...

  4. 40 CFR 52.1127 - Attainment dates for national standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... 52.1127 Section 52.1127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1127...-New Haven-Springfield Interstate Area (See 40 CFR 81.26) (a) (b) (a) (a) (a) (c) AQCR 117: Berkshire...

  5. 40 CFR 52.1127 - Attainment dates for national standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... 52.1127 Section 52.1127 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1127...-New Haven-Springfield Interstate Area (See 40 CFR 81.26) (a) (b) (a) (a) (a) (c) AQCR 117: Berkshire...

  6. 48 CFR 52.209-7 - Information Regarding Responsibility Matters.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (JUL 2013) (a) Definitions. As used in...

  7. 48 CFR 52.209-7 - Information Regarding Responsibility Matters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (JUL 2013) (a) Definitions. As used in...

  8. 48 CFR 52.209-7 - Information Regarding Responsibility Matters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Responsibility Matters. 52.209-7 Section 52.209-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.209-7 Information Regarding Responsibility Matters. As prescribed at 9.104-7(b), insert the following provision: Information Regarding Responsibility Matters (FEB 2012) (a) Definitions. As used in...

  9. Research Pilot Milt Thompson in M2-F2 Aircraft Attached to B-52 Mothership

    NASA Image and Video Library

    1966-02-28

    NASA research pilot Milt Thompson sits in the M2-F2 "heavyweight" lifting body research vehicle before a 1966 test flight. The M2-F2 and the other lifting-body designs were all attached to a wing pylon on NASA’s B-52 mothership and carried aloft. The vehicles were then drop-launched and, at the end of their flights, glided back to wheeled landings on the dry lake or runway at Edwards AFB. The lifting body designs influenced the design of the Space Shuttle and were also reincarnated in the design of the X-38 in the 1990s.

  10. 40 CFR 52.2423 - Approval status.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... section 4.55(b) of the Virginia regulations, because the regulation is not adequately enforceable. Therefore, section 4.55(b) is disapproved. (f) Section 9 VAC 5-40-20.A.3. of the Virginia Regulations for... revised, due to format changes, at §§ 52.2420(c)(89)(i)(B)(7) [SIP section 120-08-01C.4.b]. (q) EPA...

  11. 40 CFR 52.2423 - Approval status.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... section 4.55(b) of the Virginia regulations, because the regulation is not adequately enforceable. Therefore, section 4.55(b) is disapproved. (f) Section 9 VAC 5-40-20.A.3. of the Virginia Regulations for... revised, due to format changes, at §§ 52.2420(c)(89)(i)(B)(7) [SIP section 120-08-01C.4.b]. (q) EPA...

  12. 40 CFR 52.2423 - Approval status.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... section 4.55(b) of the Virginia regulations, because the regulation is not adequately enforceable. Therefore, section 4.55(b) is disapproved. (f) Section 9 VAC 5-40-20.A.3. of the Virginia Regulations for... revised, due to format changes, at §§ 52.2420(c)(89)(i)(B)(7) [SIP section 120-08-01C.4.b]. (q) EPA...

  13. Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated ARser81

    PubMed Central

    Mehraein-Ghomi, Farideh; Church, Dawn R.; Schreiber, Cynthia L.; Weichmann, Ashley M.; Basu, Hirak S.; Wilding, George

    2015-01-01

    Accumulating evidence shows that androgen receptor (AR) activation and signaling plays a key role in growth and progression in all stages of prostate cancer, even under low androgen levels or in the absence of androgen in the castration-resistant prostate cancer. Sustained activation of AR under androgen-deprived conditions may be due to its interaction with co-activators, such as p52 NF-κB subunit, and/or an increase in its stability by phosphorylation that delays its degradation. Here we identified a specific inhibitor of AR/p52 interaction, AR/p52-02, via a high throughput screen based on the reconstitution of Gaussia Luciferase. We found that AR/p52-02 markedly inhibited growth of both castration-resistant C4-2 (IC50 ∼6 μM) and parental androgen-dependent LNCaP (IC50 ∼4 μM) human prostate cancer cells under low androgen conditions. Growth inhibition was associated with significantly reduced nuclear p52 levels and DNA binding activity, as well as decreased phosphorylation of AR at serine 81, increased AR ubiquitination, and decreased AR transcriptional activity as indicated by decreased prostate-specific antigen (PSA) mRNA levels in both cell lines. AR/p52-02 also caused a reduction in levels of p21WAF/CIP1, which is a direct AR targeted gene in that its expression correlates with androgen stimulation and mitogenic proliferation in prostate cancer under physiologic levels of androgen, likely by disrupting the AR signaling axis. The reduced level of cyclinD1 reported previously for this compound may be due to the reduction in nuclear presence and activity of p52, which directly regulates cyclinD1 expression, as well as the reduction in p21WAF/CIP1, since p21WAF/CIP1 is reported to stabilize nuclear cyclinD1 in prostate cancer. Overall, the data suggest that specifically inhibiting the interaction of AR with p52 and blocking activity of p52 and pARser81 may be an effective means of reducing castration-resistant prostate cancer cell growth. PMID:26622945

  14. 7 CFR 924.52 - Issuance of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Issuance of regulations. 924.52 Section 924.52 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... the same variety to other destinations. (b) The committee shall be informed immediately of any such...

  15. 10 CFR 52.75 - Filing of applications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. (b) The application... 10 Energy 2 2014-01-01 2014-01-01 false Filing of applications. 52.75 Section 52.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined...

  16. 10 CFR 52.75 - Filing of applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. (b) The application... 10 Energy 2 2011-01-01 2011-01-01 false Filing of applications. 52.75 Section 52.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined...

  17. 10 CFR 52.75 - Filing of applications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. (b) The application... 10 Energy 2 2012-01-01 2012-01-01 false Filing of applications. 52.75 Section 52.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined...

  18. 10 CFR 52.75 - Filing of applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. (b) The application... 10 Energy 2 2010-01-01 2010-01-01 false Filing of applications. 52.75 Section 52.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined...

  19. 10 CFR 52.75 - Filing of applications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... New Reactors or Director, Office of Nuclear Reactor Regulation, as appropriate. (b) The application... 10 Energy 2 2013-01-01 2013-01-01 false Filing of applications. 52.75 Section 52.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined...

  20. Ignition of the Pegasus rocket moments after release from the B-52 signaled acceleration of the X-43

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The first X-43A hypersonic research aircraft and its modified Pegasus booster rocket were carried aloft by NASA's NB-52B carrier aircraft from Dryden Flight Research Center at Edwards Air Force Base, Calif., on June 2, 2001 for the first of three high-speed free flight attempts. About an hour and 15 minutes later the Pegasus booster was released from the B-52 to accelerate the X-43A to its intended speed of Mach 7. Before this could be achieved, the combined Pegasus and X-43A 'stack' lost control about eight seconds after ignition of the Pegasus rocket motor. The mission was terminated and explosive charges ensured the Pegasus and X-43A fell into the Pacific Ocean in a cleared Navy range area. A NASA investigation board is being assembled to determine the cause of the incident. Work continues on two other X-43A vehicles, the first of which could fly by late 2001. Central to the X-43A program is its integration of an air-breathing 'scramjet' engine that could enable a variety of high-speed aerospace craft, and promote cost-effective access to space. The 12-foot, unpiloted research vehicle was developed and built for NASA by MicroCraft Inc., Tullahoma, Tenn. The booster was built by Orbital Sciences Corp. at Chandler, Ariz. The X-43A flights are the first actual flight tests of an aircraft powered by a scramjet engine capable of operating at hypersonic speeds (above Mach 5, or five times the speed of sound). Some 90 minutes after takeoff, the Pegasus will launch from a B-52, rocketing the X-43A to Mach 7 at 95,000 feet altitude, or Mach 10 at 105,000 feet altitude. The X-43A will be powered by its revolutionary air-breathing supersonic-combustion ramjet or 'scramjet' engine. The X-43A will then fly a pre-programmed trajectory, conducting aerodynamic and propulsion experiments as it descends until it splashes into the Pacific Ocean.

  1. NASA's B-52 takes the X-38 aloft for the seventh free flight of the program, July 10, 2001

    NASA Image and Video Library

    2001-07-10

    The X-38, mounted beneath the right wing of NASA's B-52, climbed from the runway at Edwards Air Force Base for the seventh free flight test of the X-38, July 10, 2001. The X-38 was released at 37,500 feet and completed a thirteen minute glide flight to a landing on Rogers Dry Lake.

  2. NASA's B-52 takes the X-38 aloft for the seventh free flight of the program, July 10, 2001

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The X-38, mounted beneath the right wing of NASA's B-52, climbed from the runway at Edwards Air Force Base for the seventh free flight test of the X-38, July 10, 2001. The X-38 was released at 37,500 feet and completed a thirteen minute glide flight to a landing on Rogers Dry Lake.

  3. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Business Status. 52.219-22 Section 52.219-22 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-22 Small Disadvantaged Business Status. As prescribed in 19.309(b), insert the following provision: Small Disadvantaged Business Status (OCT 1999) (a) General. This provision is used to assess an...

  4. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Business Status. 52.219-22 Section 52.219-22 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-22 Small Disadvantaged Business Status. As prescribed in 19.309(b), insert the following provision: Small Disadvantaged Business Status (OCT 1999) (a) General. This provision is used to assess an...

  5. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Business Status. 52.219-22 Section 52.219-22 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-22 Small Disadvantaged Business Status. As prescribed in 19.309(b), insert the following provision: Small Disadvantaged Business Status (OCT 1999) (a) General. This provision is used to assess an...

  6. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Business Status. 52.219-22 Section 52.219-22 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-22 Small Disadvantaged Business Status. As prescribed in 19.309(b), insert the following provision: Small Disadvantaged Business Status (OCT 1999) (a) General. This provision is used to assess an...

  7. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... Status as a small business and status as a small disadvantaged business for general statistical purposes... Business Status. 52.219-22 Section 52.219-22 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-22 Small Disadvantaged Business Status. As prescribed in 19.308(b), insert the following...

  8. 15 CFR 700.52 - Examples of assistance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Examples of assistance. 700.52 Section... DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Special Priorities Assistance § 700.52 Examples of assistance... an item needed to fill a rated order. (b) Other examples of special priorities assistance include: (1...

  9. 40 CFR 52.797 - Control strategy: Lead.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Control strategy: Lead. 52.797 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.797 Control strategy: Lead. (a)-(b... request to redesignate the County to attainment of the lead standard. (e) On April 1, 2009, Indiana...

  10. 40 CFR 52.797 - Control strategy: Lead.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Control strategy: Lead. 52.797 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.797 Control strategy: Lead. (a)-(b... request to redesignate the County to attainment of the lead standard. (e) On April 1, 2009, Indiana...

  11. 40 CFR 52.797 - Control strategy: Lead.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Control strategy: Lead. 52.797 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.797 Control strategy: Lead. (a)-(b... request to redesignate the County to attainment of the lead standard. (e) On April 1, 2009, Indiana...

  12. 40 CFR 52.1116 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1116 Section 52.1116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) The following provisions of 40 CFR 52.21 are hereby incorporated and made a...

  13. 40 CFR 52.1116 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.1116 Section 52.1116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) The following provisions of 40 CFR 52.21 are hereby incorporated and made a...

  14. 40 CFR 52.1116 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1116 Section 52.1116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) The following provisions of 40 CFR 52.21 are hereby incorporated and made a...

  15. 40 CFR 52.1116 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1116 Section 52.1116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) The following provisions of 40 CFR 52.21 are hereby incorporated and made a...

  16. 40 CFR 52.1116 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1116 Section 52.1116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) The following provisions of 40 CFR 52.21 are hereby incorporated and made a...

  17. Pegasus Mated under Wing of B-52 Mothership - Close-up

    NASA Technical Reports Server (NTRS)

    1994-01-01

    A close-up view of the Pegasus space-booster attached to the wing pylon of NASA's B-52 launch aircraft at NASA's Dryden Flight Research Center, Edwards, California. The Pegasus rocket booster was designed as a way to get small payloads into space orbit more easily and cost-effectively. It has also been used to gather data on hypersonic flight. Pegasus is an air-launched space booster produced by Orbital Sciences Corporation and Hercules Aerospace Company (initially; later, Alliant Tech Systems) to provide small satellite users with a cost-effective, flexible, and reliable method for placing payloads into low earth orbit. Pegasus has been used to launch a number of satellites and the PHYSX experiment. That experiment consisted of a smooth glove installed on the first-stage delta wing of the Pegasus. The glove was used to gather data at speeds of up to Mach 8 and at altitudes approaching 200,000 feet. The flight took place on October 22, 1998. The PHYSX experiment focused on determining where boundary-layer transition occurs on the glove and on identifying the flow mechanism causing transition over the glove. Data from this flight-research effort included temperature, heat transfer, pressure measurements, airflow, and trajectory reconstruction. Hypersonic flight-research programs are an approach to validate design methods for hypersonic vehicles (those that fly more than five times the speed of sound, or Mach 5). Dryden Flight Research Center, Edwards, California, provided overall management of the glove experiment, glove design, and buildup. Dryden also was responsible for conducting the flight tests. Langley Research Center, Hampton, Virginia, was responsible for the design of the aerodynamic glove as well as development of sensor and instrumentation systems for the glove. Other participating NASA centers included Ames Research Center, Mountain View, California; Goddard Space Flight Center, Greenbelt, Maryland; and Kennedy Space Center, Florida. Orbital Sciences

  18. 32 CFR 701.52 - Computation of fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... correspondence and preparation costs, these fees are not recoupable from the requester. (b) DD 2086, Record of... costs, as requesters may solicit a copy of that document to ensure accurate computation of fees. Costs... 32 National Defense 5 2010-07-01 2010-07-01 false Computation of fees. 701.52 Section 701.52...

  19. 40 CFR 52.2076 - Attainment of dates for national standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... standards. 52.2076 Section 52.2076 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2076... better than primary standards or area is unclassifiable. b Air quality levels presently better than...

  20. 40 CFR 52.2076 - Attainment of dates for national standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standards. 52.2076 Section 52.2076 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2076... better than primary standards or area is unclassifiable. b Air quality levels presently better than...

  1. 40 CFR 52.2076 - Attainment of dates for national standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... standards. 52.2076 Section 52.2076 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2076... better than primary standards or area is unclassifiable. b Air quality levels presently better than...

  2. 40 CFR 52.2076 - Attainment of dates for national standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... standards. 52.2076 Section 52.2076 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2076... better than primary standards or area is unclassifiable. b Air quality levels presently better than...

  3. 40 CFR 52.2076 - Attainment of dates for national standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standards. 52.2076 Section 52.2076 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2076... better than primary standards or area is unclassifiable. b Air quality levels presently better than...

  4. 40 CFR 52.2525 - Control strategy: Sulfur dioxide.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Control strategy: Sulfur dioxide. 52.2525 Section 52.2525 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... strategy: Sulfur dioxide. (a) [Reserved] (b) EPA approves the attainment demonstration State Implementation...

  5. 40 CFR 52.2033 - Control strategy: Sulfur oxides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Control strategy: Sulfur oxides. 52.2033 Section 52.2033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... strategy: Sulfur oxides. (a) [Reserved] (b) EPA approves the attainment demonstration State Implementation...

  6. 47 CFR 52.25 - Database architecture and administration.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Database architecture and administration. 52.25... (CONTINUED) NUMBERING Number Portability § 52.25 Database architecture and administration. (a) The North... databases for the provision of long-term database methods for number portability. (b) All telecommunications...

  7. 47 CFR 52.25 - Database architecture and administration.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Database architecture and administration. 52.25... (CONTINUED) NUMBERING Number Portability § 52.25 Database architecture and administration. (a) The North... databases for the provision of long-term database methods for number portability. (b) All telecommunications...

  8. 47 CFR 52.25 - Database architecture and administration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Database architecture and administration. 52.25... (CONTINUED) NUMBERING Number Portability § 52.25 Database architecture and administration. (a) The North... databases for the provision of long-term database methods for number portability. (b) All telecommunications...

  9. 47 CFR 52.25 - Database architecture and administration.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Database architecture and administration. 52.25... (CONTINUED) NUMBERING Number Portability § 52.25 Database architecture and administration. (a) The North... databases for the provision of long-term database methods for number portability. (b) All telecommunications...

  10. 47 CFR 52.25 - Database architecture and administration.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Database architecture and administration. 52.25... (CONTINUED) NUMBERING Number Portability § 52.25 Database architecture and administration. (a) The North... databases for the provision of long-term database methods for number portability. (b) All telecommunications...

  11. 40 CFR 52.1974-52.1976 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1974-52.1976 Section 52.1974-52.1976 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1974-52.1976 [Reserved] ...

  12. 40 CFR 52.1978-52.1981 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1978-52.1981 Section 52.1978-52.1981 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1978-52.1981 [Reserved] ...

  13. 40 CFR 52.1983-52.1986 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false [Reserved] 52.1983-52.1986 Section 52.1983-52.1986 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1983-52.1986 [Reserved] ...

  14. 40 CFR 52.1983-52.1986 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1983-52.1986 Section 52.1983-52.1986 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1983-52.1986 [Reserved] ...

  15. 40 CFR 52.1978-52.1981 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1978-52.1981 Section 52.1978-52.1981 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1978-52.1981 [Reserved] ...

  16. 40 CFR 52.1978-52.1981 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1978-52.1981 Section 52.1978-52.1981 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1978-52.1981 [Reserved] ...

  17. 40 CFR 52.1974-52.1976 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false [Reserved] 52.1974-52.1976 Section 52.1974-52.1976 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1974-52.1976 [Reserved] ...

  18. 40 CFR 52.1983-52.1986 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1983-52.1986 Section 52.1983-52.1986 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1983-52.1986 [Reserved] ...

  19. 40 CFR 52.1974-52.1976 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1974-52.1976 Section 52.1974-52.1976 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1974-52.1976 [Reserved] ...

  20. 40 CFR 52.1983-52.1986 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1983-52.1986 Section 52.1983-52.1986 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1983-52.1986 [Reserved] ...

  1. 40 CFR 52.1975-52.1976 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1975-52.1976 Section 52.1975-52.1976 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1975-52.1976 [Reserved] ...

  2. 40 CFR 52.1978-52.1981 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false [Reserved] 52.1978-52.1981 Section 52.1978-52.1981 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1978-52.1981 [Reserved] ...

  3. 40 CFR 52.1992-52.2019 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1992-52.2019 Section 52.1992-52.2019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oregon §§ 52.1992-52.2019 [Reserved] ...

  4. 40 CFR 52.1226-52.1229 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1226-52.1229 Section 52.1226-52.1229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1226-52.1229...

  5. 40 CFR 52.1226-52.1229 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1226-52.1229 Section 52.1226-52.1229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1226-52.1229...

  6. 40 CFR 52.1231-52.1232 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1231-52.1232 Section 52.1231-52.1232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1231-52.1232...

  7. 40 CFR 52.1226-52.1229 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false [Reserved] 52.1226-52.1229 Section 52.1226-52.1229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1226-52.1229...

  8. 40 CFR 52.1231-52.1232 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false [Reserved] 52.1231-52.1232 Section 52.1231-52.1232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1231-52.1232...

  9. 40 CFR 52.1231-52.1232 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1231-52.1232 Section 52.1231-52.1232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1231-52.1232...

  10. 40 CFR 52.1231-52.1232 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false [Reserved] 52.1231-52.1232 Section 52.1231-52.1232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1231-52.1232...

  11. 40 CFR 52.1226-52.1229 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1226-52.1229 Section 52.1226-52.1229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1226-52.1229...

  12. 40 CFR 52.1226-52.1229 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false [Reserved] 52.1226-52.1229 Section 52.1226-52.1229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1226-52.1229...

  13. 40 CFR 52.1231-52.1232 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false [Reserved] 52.1231-52.1232 Section 52.1231-52.1232 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Minnesota §§ 52.1231-52.1232...

  14. 40 CFR 52.1686-52.1688 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1686-52.1688 Section 52.1686-52.1688 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New York §§ 52.1686-52.1688...

  15. 40 CFR 52.2727-52.2728 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.2727-52.2728 Section 52.2727-52.2728 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico §§ 52.2727-52.2728...

  16. 40 CFR 52.2727-52.2728 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false [Reserved] 52.2727-52.2728 Section 52.2727-52.2728 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico §§ 52.2727-52.2728...

  17. 40 CFR 52.2727-52.2728 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.2727-52.2728 Section 52.2727-52.2728 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Puerto Rico §§ 52.2727-52.2728...

  18. 40 CFR 52.627-52.631 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false [Reserved] 52.627-52.631 Section 52.627-52.631 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Hawaii §§ 52.627-52.631 [Reserved] ...

  19. 40 CFR 52.678-52.680 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false [Reserved] 52.678-52.680 Section 52.678-52.680 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Idaho §§ 52.678-52.680 [Reserved] ...

  20. 40 CFR 52.684-52.689 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false [Reserved] 52.684-52.689 Section 52.684-52.689 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Idaho §§ 52.684-52.689 [Reserved] ...

  1. 40 CFR 52.2582-52.2583 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false [Reserved] 52.2582-52.2583 Section 52.2582-52.2583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2582-52.2583...

  2. 40 CFR 52.2579-52.2580 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 5 2012-07-01 2012-07-01 false [Reserved] 52.2579-52.2580 Section 52.2579-52.2580 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2579-52.2580...

  3. 40 CFR 52.2582-52.2583 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.2582-52.2583 Section 52.2582-52.2583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2582-52.2583...

  4. 40 CFR 52.2582-52.2583 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 5 2012-07-01 2012-07-01 false [Reserved] 52.2582-52.2583 Section 52.2582-52.2583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2582-52.2583...

  5. 40 CFR 52.2579-52.2580 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false [Reserved] 52.2579-52.2580 Section 52.2579-52.2580 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2579-52.2580...

  6. 40 CFR 52.2582-52.2583 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 5 2013-07-01 2013-07-01 false [Reserved] 52.2582-52.2583 Section 52.2582-52.2583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2582-52.2583...

  7. 40 CFR 52.2579-52.2580 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.2579-52.2580 Section 52.2579-52.2580 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2579-52.2580...

  8. 40 CFR 52.2582-52.2583 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.2582-52.2583 Section 52.2582-52.2583 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2582-52.2583...

  9. 40 CFR 52.2579-52.2580 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.2579-52.2580 Section 52.2579-52.2580 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2579-52.2580...

  10. 40 CFR 52.2579-52.2580 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 5 2013-07-01 2013-07-01 false [Reserved] 52.2579-52.2580 Section 52.2579-52.2580 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wisconsin §§ 52.2579-52.2580...

  11. 40 CFR 52.1776-52.1777 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false [Reserved] 52.1776-52.1777 Section 52.1776-52.1777 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) North Carolina §§ 52.1776-52.1777...

  12. 40 CFR 52.1776-52.1777 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false [Reserved] 52.1776-52.1777 Section 52.1776-52.1777 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) North Carolina §§ 52.1776-52.1777...

  13. 48 CFR 52.216-17 - Incentive Price Revision-Successive Targets.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-Successive Targets. 52.216-17 Section 52.216-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.216-17 Incentive Price Revision—Successive Targets. As prescribed in 16.406(b), insert the following clause: Incentive Price Revision—Successive Targets (OCT 1997) (a) General. The supplies or...

  14. 48 CFR 52.216-17 - Incentive Price Revision-Successive Targets.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-Successive Targets. 52.216-17 Section 52.216-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.216-17 Incentive Price Revision—Successive Targets. As prescribed in 16.406(b), insert the following clause: Incentive Price Revision—Successive Targets (OCT 1997) (a) General. The supplies or...

  15. 48 CFR 52.249-7 - Termination (Fixed-Price Architect-Engineer).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Architect-Engineer). 52.249-7 Section 52.249-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.249-7 Termination (Fixed-Price Architect-Engineer). As prescribed in 49.503(b), insert the following clause in solicitations and contracts for architect-engineer services when a fixed-price contract...

  16. 48 CFR 52.249-7 - Termination (Fixed-Price Architect-Engineer).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Architect-Engineer). 52.249-7 Section 52.249-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.249-7 Termination (Fixed-Price Architect-Engineer). As prescribed in 49.503(b), insert the following clause in solicitations and contracts for architect-engineer services when a fixed-price contract...

  17. 48 CFR 52.249-7 - Termination (Fixed-Price Architect-Engineer).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Architect-Engineer). 52.249-7 Section 52.249-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.249-7 Termination (Fixed-Price Architect-Engineer). As prescribed in 49.503(b), insert the following clause in solicitations and contracts for architect-engineer services when a fixed-price contract...

  18. 48 CFR 52.249-7 - Termination (Fixed-Price Architect-Engineer).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Architect-Engineer). 52.249-7 Section 52.249-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.249-7 Termination (Fixed-Price Architect-Engineer). As prescribed in 49.503(b), insert the following clause in solicitations and contracts for architect-engineer services when a fixed-price contract...

  19. 33 CFR 52.52 - Notice of hearing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Notice of hearing. 52.52 Section 52.52 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PERSONNEL BOARD FOR CORRECTION OF MILITARY RECORDS OF THE COAST GUARD Hearings § 52.52 Notice of hearing. (a) If the...

  20. 33 CFR 52.52 - Notice of hearing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Notice of hearing. 52.52 Section 52.52 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PERSONNEL BOARD FOR CORRECTION OF MILITARY RECORDS OF THE COAST GUARD Hearings § 52.52 Notice of hearing. (a) If the...

  1. 48 CFR 52.204-13 - System for Award Management Maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Management Maintenance. 52.204-13 Section 52.204-13 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.204-13 System for Award Management Maintenance. As prescribed in 4.1105(b), use the following clause: System for Award Management Maintenance (JUL 2013) (a) Definitions. As used in this clause...

  2. 40 CFR 52.1475 - Control strategy and regulations: Sulfur oxides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...: Sulfur oxides. 52.1475 Section 52.1475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 52.1475 Control strategy and regulations: Sulfur oxides. (a) The requirements of subpart G of this... National Ambient Air Quality Standards for sulfur oxides in the Nevada Intrastate Region. (b) Article 8.1.3...

  3. 40 CFR 52.1475 - Control strategy and regulations: Sulfur oxides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...: Sulfur oxides. 52.1475 Section 52.1475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 52.1475 Control strategy and regulations: Sulfur oxides. (a) The requirements of subpart G of this... National Ambient Air Quality Standards for sulfur oxides in the Nevada Intrastate Region. (b) Article 8.1.3...

  4. 40 CFR 52.1475 - Control strategy and regulations: Sulfur oxides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...: Sulfur oxides. 52.1475 Section 52.1475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 52.1475 Control strategy and regulations: Sulfur oxides. (a) The requirements of subpart G of this... National Ambient Air Quality Standards for sulfur oxides in the Nevada Intrastate Region. (b) Article 8.1.3...

  5. 40 CFR 52.1475 - Control strategy and regulations: Sulfur oxides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...: Sulfur oxides. 52.1475 Section 52.1475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 52.1475 Control strategy and regulations: Sulfur oxides. (a) The requirements of subpart G of this... National Ambient Air Quality Standards for sulfur oxides in the Nevada Intrastate Region. (b) Article 8.1.3...

  6. 40 CFR 52.1475 - Control strategy and regulations: Sulfur oxides.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...: Sulfur oxides. 52.1475 Section 52.1475 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 52.1475 Control strategy and regulations: Sulfur oxides. (a) The requirements of subpart G of this... National Ambient Air Quality Standards for sulfur oxides in the Nevada Intrastate Region. (b) Article 8.1.3...

  7. 10 CFR 52.83 - Finality of referenced NRC approvals; partial initial decision on site suitability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....145, and 52.171. (b) While a partial decision on site suitability is in effect under 10 CFR 2.617(b)(2... decision on site suitability. 52.83 Section 52.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.83 Finality of referenced NRC...

  8. 10 CFR 52.83 - Finality of referenced NRC approvals; partial initial decision on site suitability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....145, and 52.171. (b) While a partial decision on site suitability is in effect under 10 CFR 2.617(b)(2... decision on site suitability. 52.83 Section 52.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.83 Finality of referenced NRC...

  9. Genome-wide identification of 52 cytochrome P450 (CYP) genes in the copepod Tigriopus japonicus and their B[α]P-induced expression patterns.

    PubMed

    Han, Jeonghoon; Kim, Duck-Hyun; Kim, Hui-Su; Nelson, David R; Lee, Jae-Seong

    2017-09-01

    Cytochrome P450s (CYPs) are enzymes with a heme-binding domain that are found in all living organisms. CYP enzymes have important roles associated with detoxification of xenobiotics and endogenous compounds (e.g. steroids, fatty acids, and hormones). Although CYP enzymes have been reported in several invertebrates, including insects, little is known about copepod CYPs. Here, we identified the entire repertoire of CYP genes (n=52) from whole genome and transcriptome sequences of the benthic copepod Tigriopus japonicus, including a tandem duplication (CYP3026A3, CYP3026A4, CYP3026A5), and examined patterns of gene expression over various developmental stages and in response to benzo[α]pyrene (B[α]P) exposure. Through phylogenetic analysis, the 52 T. japonicus CYP genes were assigned to five distinct clans: CYP2 (22 genes), CYP3 (19 genes), CYP4 (two genes), CYP20 (one gene), and mitochondrial (eight genes). Developmental stage and gender-specific expression patterns of the 52 T. japonicus CYPs were analyzed. CYP3022A1 was constitutively expressed during all developmental stages. CYP genes in clans 2 and 3 were induced in response to B[α]P, suggesting that these differentially modulated CYP transcripts are likely involved in defense against exposure to B[α]P and other pollutants. This study enhances our understanding of the repertoire of CYP genes in copepods and of their potential role in development and detoxification in copepods. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Continuous lake-sediment records of glaciation in the Sierra Nevada between 52,600 and 12,500 14C yr B.P.

    USGS Publications Warehouse

    Benson, L.V.; May, Howard M.; Antweiler, Ronald C.; Brinton, T.I.; Kashgarian, Michaele; Smoot, J.P.; Lund, S.P.

    1998-01-01

    The chemistry of the carbonate-free clay-size fraction of Owens Lake sediments supports the use of total organic carbon and magnetic susceptibility as indicators of stadial-interstadial oscillations. Owens Lake records of total organic carbon, magnetic susceptibility, and chemical composition of the carbonate-free, clay-size fraction indicate that Tioga glaciation began ~24,500 and ended by ~13,600 14C yr B.P. Many of the components of glacial rock flour (e.g., TiO2, MnO, BaO) found in Owens Lake sediments achieved maximum values during the Tioga glaciation when valley glaciers reached their greatest extent. Total organic carbon and SiO2 (amorphous) concentrations reached minimum values during Tioga glaciation, resulting from decreases in productivity that accompanied the introduction of rock flour into the surface waters of Owens Lake. At least 20 stadial-interstadial oscillations occurred in the Sierra Nevada between 52,600 and 14,000 14C yr B.P. Total organic carbon data from a Pyramid Lake sediment core also indicate oscillations in glacier activity between >39,500 and ~13,600 14C yr B.P. Alpine glacier oscillations occurred on a frequency of ???1900 yr in both basins, suggesting that millennial-scale oscillations occurred in California and Nevada during most of the past 52,600 yr.

  11. 7 CFR 1218.52 - Assessments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Expenses and Assessments § 1218.52... therein. (b) The collection of assessments on domestic blueberries will be the responsibility of the first...

  12. 7 CFR 1218.52 - Assessments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Expenses and Assessments § 1218.52... therein. (b) The collection of assessments on domestic blueberries will be the responsibility of the first...

  13. 7 CFR 1218.52 - Assessments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Expenses and Assessments § 1218.52... therein. (b) The collection of assessments on domestic blueberries will be the responsibility of the first...

  14. 7 CFR 1218.52 - Assessments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Expenses and Assessments § 1218.52... therein. (b) The collection of assessments on domestic blueberries will be the responsibility of the first...

  15. 7 CFR 1218.52 - Assessments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BLUEBERRY PROMOTION, RESEARCH, AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Expenses and Assessments § 1218.52... therein. (b) The collection of assessments on domestic blueberries will be the responsibility of the first...

  16. 40 CFR 52.2233 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Significant deterioration of air quality. 52.2233 Section 52.2233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... requesting innovative technology waivers which would significantly impact air quality in adjacent states. (2...

  17. 40 CFR 52.276 - Sulfur content of fuels.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Sulfur content of fuels. 52.276 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.276 Sulfur content of fuels. (a) The...), Sulfur Content of Fuels, submitted on October 23, 1974. (b) The deletion of the following rules from the...

  18. 40 CFR 52.276 - Sulfur content of fuels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Sulfur content of fuels. 52.276 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.276 Sulfur content of fuels. (a) The...), Sulfur Content of Fuels, submitted on October 23, 1974. (b) The deletion of the following rules from the...

  19. 40 CFR 52.276 - Sulfur content of fuels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Sulfur content of fuels. 52.276 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.276 Sulfur content of fuels. (a) The...), Sulfur Content of Fuels, submitted on October 23, 1974. (b) The deletion of the following rules from the...

  20. 40 CFR 52.276 - Sulfur content of fuels.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Sulfur content of fuels. 52.276 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.276 Sulfur content of fuels. (a) The...), Sulfur Content of Fuels, submitted on October 23, 1974. (b) The deletion of the following rules from the...

  1. 40 CFR 52.276 - Sulfur content of fuels.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Sulfur content of fuels. 52.276 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.276 Sulfur content of fuels. (a) The...), Sulfur Content of Fuels, submitted on October 23, 1974. (b) The deletion of the following rules from the...

  2. 40 CFR 52.2451 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2451 Section 52.2451 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for preventing significant deterioration of air quality. The...

  3. 40 CFR 52.2528 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2528 Section 52.2528 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of Sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for Preventing Significant Deterioration of Air Quality, the...

  4. 40 CFR 52.2528 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2528 Section 52.2528 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of Sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for Preventing Significant Deterioration of Air Quality, the...

  5. 40 CFR 52.2451 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2451 Section 52.2451 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for preventing significant deterioration of air quality. The...

  6. 40 CFR 52.2451 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2451 Section 52.2451 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for preventing significant deterioration of air quality. The...

  7. 40 CFR 52.2451 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2451 Section 52.2451 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for preventing significant deterioration of air quality. The...

  8. 40 CFR 52.2528 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2528 Section 52.2528 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of Sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for Preventing Significant Deterioration of Air Quality, the...

  9. 40 CFR 52.2451 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.2451 Section 52.2451 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for preventing significant deterioration of air quality. The...

  10. 40 CFR 52.2528 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.2528 Section 52.2528 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of Sections 160 through 165 of the Clean Air... Quality Deterioration. (b) Regulations for Preventing Significant Deterioration of Air Quality, the...

  11. A modified Pegasus rocket ignites moments after release from the B-52B, beginning the acceleration of the X-43A over the Pacific Ocean on March 27, 2004

    NASA Image and Video Library

    2004-03-27

    The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean on March 27, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif. Minutes later the X-43A separated from the Pegasus booster and accelerated to its intended speed of Mach 7. In a combined research effort involving Dryden, Langley, and several industry partners, NASA demonstrated the value of its X-43A hypersonic research aircraft, as it became the first air-breathing, unpiloted, scramjet-powered plane to fly freely by itself. The March 27 flight, originating from NASA's Dryden Flight Research Center, began with the Agency's B-52B launch aircraft carrying the X-43A out to the test range over the Pacific Ocean off the California coast. The X-43A was boosted up to its test altitude of about 95,000 feet, where it separated from its modified Pegasus booster and flew freely under its own power. Two very significant aviation milestones occurred during this test flight: first, controlled accelerating flight at Mach 7 under scramjet power, and second, the successful stage separation at high dynamic pressure of two non-axisymmetric vehicles. To top it all off, the flight resulted in the setting of a new aeronautical speed record. The X-43A reached a speed of over Mach 7, or about 5,000 miles per hour faster than any known aircraft powered by an air-breathing engine has ever flown.

  12. 40 CFR 52.2233 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2233 Section 52.2233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)(1) Paragraph 1200-3-9-.01(4)-(0)-2. of Tennessee's regulations... requesting innovative technology waivers which would significantly impact air quality in adjacent states. (2...

  13. 40 CFR 52.2233 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2233 Section 52.2233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)(1) Paragraph 1200-3-9-.01(4)-(0)-2. of Tennessee's regulations... requesting innovative technology waivers which would significantly impact air quality in adjacent states. (2...

  14. 40 CFR 52.2233 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2233 Section 52.2233 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)(1) Paragraph 1200-3-9-.01(4)-(0)-2. of Tennessee's regulations... requesting innovative technology waivers which would significantly impact air quality in adjacent states. (2...

  15. On display during a technical exposition at Dryden are NASA's B-52 launch aircraft, Boeing's X-37, B

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Aerospace industry representatives view actual and mock-up versions of 'X-Planes' intended to enhance access to space during a technical exposition on June 22, 2000 at Dryden Flight Research Center, Edwards, California. From left to right: NASA's B-52 launch aircraft, in service with NASA since 1959; a neutral-buoyancy model of the Boeing's X-37; the Boeing X-40A behind the MicroCraft X-43 mock-up; Orbital Science's X-34 and the modified Lockheed L-1011 airliner that was to launch the X-34. These X-vehicles are part of NASA's Access to Space plan intended to bring new technologies to bear in an effort to dramatically lower the cost of putting payloads in space, and near-space environments. The June 22, 2000 NASA Reusable Launch Vehicle (RLV) Technology Exposition included presentations on the history, present, and future of NASA's RLV program. Special Sessions for industry representatives highlighted the X-37 project and its related technologies. The X-37 project is managed by NASA's Marshall Space Flight Center, Huntsville, Alabama.

  16. Fine mapping of the chromosome 5B region carrying closely linked rust resistance genes Yr47 and Lr52 in wheat

    USDA-ARS?s Scientific Manuscript database

    The widely effective and linked rust resistance genes Yr47 and Lr52 were previously mapped in the short arm of chromosome 5B in two F3 populations (Aus28183/Aus27229 and Aus28187/Aus27229). The Aus28183/Aus27229 F3 population was advanced to generate an F6 recombinant inbred line (RIL) population t...

  17. 40 CFR 52.1234 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1234 Section 52.1234 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  18. 40 CFR 52.1884 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1884 Section 52.1884 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  19. 40 CFR 52.499 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.499 Section 52.499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  20. 40 CFR 52.1778 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information... Resources, Division of Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local...

  1. 40 CFR 52.1180 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1180 Section 52.1180 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  2. 40 CFR 52.2827 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2827 Section 52.2827 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  3. 40 CFR 52.1485 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1485 Section 52.1485 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... include approvable procedures for preventing the significant deterioration of air quality. (b) Regulation...

  4. 40 CFR 52.2178 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2178 Section 52.2178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The South Dakota plan, as submitted, is approved as meeting the... on Indian reservations; (b) Regulations for preventing significant deterioration of air quality. The...

  5. 40 CFR 52.1689 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1689 Section 52.1689 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  6. 40 CFR 52.2676 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2676 Section 52.2676 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  7. 40 CFR 52.2779 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2779 Section 52.2779 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  8. 40 CFR 52.2729 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2729 Section 52.2729 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  9. 40 CFR 52.2497 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2497 Section 52.2497 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  10. 40 CFR 52.2131 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Significant deterioration of air quality. 52.2131 Section 52.2131 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information...

  11. 40 CFR 52.2346 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.2346 Section 52.2346 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The Utah plan, as submitted, is approved as meeting the... construct on Indian Reservations. (b) Regulation for prevention of significant deterioration of air quality...

  12. 40 CFR 52.1603 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1603 Section 52.1603 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  13. 40 CFR 52.1165 - Significant deterioration of air quality.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... quality. 52.1165 Section 52.1165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulation for preventing significant deterioration of air quality. The...

  14. 40 CFR 52.1778 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information... Resources, Division of Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local...

  15. 40 CFR 52.499 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.499 Section 52.499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  16. 40 CFR 52.1884 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1884 Section 52.1884 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  17. 40 CFR 52.1165 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.1165 Section 52.1165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulation for preventing significant deterioration of air quality. The...

  18. 40 CFR 52.1778 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information... Resources, Division of Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local...

  19. 40 CFR 52.1165 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1165 Section 52.1165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulation for preventing significant deterioration of air quality. The...

  20. 40 CFR 52.1180 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1180 Section 52.1180 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  1. 40 CFR 52.2729 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2729 Section 52.2729 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  2. 40 CFR 52.1485 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1485 Section 52.1485 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... include approvable procedures for preventing the significant deterioration of air quality. (b) Regulation...

  3. 40 CFR 52.1884 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1884 Section 52.1884 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  4. 40 CFR 52.2779 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2779 Section 52.2779 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  5. 40 CFR 52.499 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.499 Section 52.499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  6. 40 CFR 52.1485 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.1485 Section 52.1485 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... include approvable procedures for preventing the significant deterioration of air quality. (b) Regulation...

  7. 40 CFR 52.1603 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1603 Section 52.1603 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  8. 40 CFR 52.1234 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1234 Section 52.1234 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  9. 40 CFR 52.2497 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.2497 Section 52.2497 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  10. 40 CFR 52.2497 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2497 Section 52.2497 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  11. 40 CFR 52.1603 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1603 Section 52.1603 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  12. 40 CFR 52.1884 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1884 Section 52.1884 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  13. 40 CFR 52.2676 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2676 Section 52.2676 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  14. 40 CFR 52.1778 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information... Resources, Division of Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local...

  15. 40 CFR 52.2131 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Significant deterioration of air quality. 52.2131 Section 52.2131 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information...

  16. 40 CFR 52.1603 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.1603 Section 52.1603 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  17. 40 CFR 52.2131 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Significant deterioration of air quality. 52.2131 Section 52.2131 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information...

  18. 40 CFR 52.499 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.499 Section 52.499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  19. 40 CFR 52.2676 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2676 Section 52.2676 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  20. 40 CFR 52.2779 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2779 Section 52.2779 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  1. 40 CFR 52.1234 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1234 Section 52.1234 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  2. 40 CFR 52.2676 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.2676 Section 52.2676 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  3. 40 CFR 52.1165 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1165 Section 52.1165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulation for preventing significant deterioration of air quality. The...

  4. 40 CFR 52.2178 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2178 Section 52.2178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The South Dakota plan, as submitted, is approved as meeting the... on Indian reservations; (b) Regulations for preventing significant deterioration of air quality. The...

  5. 40 CFR 52.2178 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2178 Section 52.2178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The South Dakota plan, as submitted, is approved as meeting the... on Indian reservations; (b) Regulations for preventing significant deterioration of air quality. The...

  6. 40 CFR 52.2827 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2827 Section 52.2827 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  7. 40 CFR 52.1165 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1165 Section 52.1165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulation for preventing significant deterioration of air quality. The...

  8. 40 CFR 52.1485 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.1485 Section 52.1485 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... include approvable procedures for preventing the significant deterioration of air quality. (b) Regulation...

  9. 40 CFR 52.1180 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1180 Section 52.1180 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  10. 40 CFR 52.2178 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.2178 Section 52.2178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The South Dakota plan, as submitted, is approved as meeting the... on Indian reservations; (b) Regulations for preventing significant deterioration of air quality. The...

  11. 40 CFR 52.2676 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2676 Section 52.2676 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  12. 40 CFR 52.2497 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.2497 Section 52.2497 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  13. 40 CFR 52.1485 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1485 Section 52.1485 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... include approvable procedures for preventing the significant deterioration of air quality. (b) Regulation...

  14. 40 CFR 52.2178 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.2178 Section 52.2178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The South Dakota plan, as submitted, is approved as meeting the... on Indian reservations; (b) Regulations for preventing significant deterioration of air quality. The...

  15. 40 CFR 52.499 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... quality. 52.499 Section 52.499 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  16. 40 CFR 52.2729 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2729 Section 52.2729 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  17. 40 CFR 52.1778 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... quality. 52.1778 Section 52.1778 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information... Resources, Division of Air Quality, 1641 Mail Service Center, Raleigh, North Carolina 27699-1641 or local...

  18. 40 CFR 52.1180 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... quality. 52.1180 Section 52.1180 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  19. 40 CFR 52.2497 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... quality. 52.2497 Section 52.2497 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a) The requirements of sections 160 through 165 of the Clean Air... deterioration of air quality. (b) Regulations for preventing significant deterioration of air quality. The...

  20. 40 CFR 52.2131 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Significant deterioration of air quality. 52.2131 Section 52.2131 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Significant deterioration of air quality. (a)-(b) [Reserved] (c) All applications and other information...