Impact of advanced onboard processing concepts on end-to-end data system

NASA Technical Reports Server (NTRS)

Sos, J. Y.

1978-01-01

An investigation is conducted of the impact of advanced onboard data handling concepts on the total system in general and on ground processing operations, such as those being performed in the central data processing facility of the NASA Goddard Space Flight Center. In one of these concepts, known as the instrument telemetry packet (ITP) system, telemetry data from a single instrument is encoded into a packet, along with other ancillary data, and transmitted in this form to the ground. Another concept deals with onboard temporal registration of image data from such sensors as the thematic mapper, to be carried onboard the Landsat-D spacecraft in 1981. It is found that the implementation of the considered concepts will result in substantial simplification of the ground processing element of the system. With the projected tenfold increase in the data volume expected in the next decade, the introduction of ITP should keep the cost of the ground data processing function within reasonable bounds and significantly contribute to a more timely delivery of data/information to the end user.

Ripple-aware optical proximity correction fragmentation for back-end-of-line designs

NASA Astrophysics Data System (ADS)

Wang, Jingyu; Wilkinson, William

2018-01-01

Accurate characterization of image rippling is critical in early detection of back-end-of-line (BEOL) patterning weakpoints, as most defects are strongly associated with excessive rippling that does not get effectively compensated by optical proximity correction (OPC). We correlate image contour with design shapes to account for design geometry-dependent rippling signature, and explore the best practice of OPC fragmentation for BEOL geometries. Specifically, we predict the optimum contour as allowed by the lithographic process and illumination conditions and locate ripple peaks, valleys, and inflection points. This allows us to identify potential process weakpoints and segment the mask accordingly to achieve the best correction results.

Visualization for Hyper-Heuristics: Back-End Processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simon, Luke

Modern society is faced with increasingly complex problems, many of which can be formulated as generate-and-test optimization problems. Yet, general-purpose optimization algorithms may sometimes require too much computational time. In these instances, hyperheuristics may be used. Hyper-heuristics automate the design of algorithms to create a custom algorithm for a particular scenario, finding the solution significantly faster than its predecessor. However, it may be difficult to understand exactly how a design was derived and why it should be trusted. This project aims to address these issues by creating an easy-to-use graphical user interface (GUI) for hyper-heuristics and an easy-to-understand scientific visualizationmore » for the produced solutions. To support the development of this GUI, my portion of the research involved developing algorithms that would allow for parsing of the data produced by the hyper-heuristics. This data would then be sent to the front-end, where it would be displayed to the end user.« less

Characteristic of a Digital Correlation Radiometer Back End with Finite Wordlength

NASA Technical Reports Server (NTRS)

Biswas, Sayak K.; Hyde, David W.; James, Mark W.; Cecil, Daniel J.

2017-01-01

The performance characteristic of a digital correlation radiometer signal processing back end (DBE) is analyzed using a simulator. The particular design studied here corresponds to the airborne Hurricane Imaging radiometer which was jointly developed by the NASA Marshall Space Flight Center, University of Michigan, University of Central Florida and NOAA. Laboratory and flight test data is found to be in accord with the simulation results. Overall design seems to be optimum for the typical input signal dynamic range. It was found that the performance of the digital kurtosis could be improved by lowering the DBE input power level. An unusual scaling between digital correlation channels observed in the instrument data is confirmed to be a DBE characteristic.

A hybrid single-end-access MZI and Φ-OTDR vibration sensing system with high frequency response

NASA Astrophysics Data System (ADS)

Zhang, Yixin; Xia, Lan; Cao, Chunqi; Sun, Zhenhong; Li, Yanting; Zhang, Xuping

2017-01-01

A hybrid single-end-access Mach-Zehnder interferometer (MZI) and phase sensitive OTDR (Φ-OTDR) vibration sensing system is proposed and demonstrated experimentally. In our system, the narrow optical pulses and the continuous wave are injected into the fiber through the front end of the fiber at the same time. And at the rear end of the fiber, a frequency-shift-mirror (FSM) is designed to back propagate the continuous wave modulated by the external vibration. Thus the Rayleigh backscattering signals (RBS) and the back propagated continuous wave interfere with the reference light at the same end of the sensing fiber and a single-end-access configuration is achieved. The RBS can be successfully separated from the interference signal (IS) through digital signal process due to their different intermediate frequency based on frequency division multiplexing technique. There is no influence between these two schemes. The experimental results show 10 m spatial resolution and up to 1.2 MHz frequency response along a 6.35 km long fiber. This newly designed single-end-access setup can achieve vibration events locating and high frequency events response, which can be widely used in health monitoring for civil infrastructures and transportation.

An open-source data storage and visualization back end for experimental data.

PubMed

Nielsen, Kenneth; Andersen, Thomas; Jensen, Robert; Nielsen, Jane H; Chorkendorff, Ib

2014-04-01

In this article, a flexible free and open-source software system for data logging and presentation will be described. The system is highly modular and adaptable and can be used in any laboratory in which continuous and/or ad hoc measurements require centralized storage. A presentation component for the data back end has furthermore been written that enables live visualization of data on any device capable of displaying Web pages. The system consists of three parts: data-logging clients, a data server, and a data presentation Web site. The logging of data from independent clients leads to high resilience to equipment failure, whereas the central storage of data dramatically eases backup and data exchange. The visualization front end allows direct monitoring of acquired data to see live progress of long-duration experiments. This enables the user to alter experimental conditions based on these data and to interfere with the experiment if needed. The data stored consist both of specific measurements and of continuously logged system parameters. The latter is crucial to a variety of automation and surveillance features, and three cases of such features are described: monitoring system health, getting status of long-duration experiments, and implementation of instant alarms in the event of failure.

Web-based DAQ systems: connecting the user and electronics front-ends

NASA Astrophysics Data System (ADS)

Lenzi, Thomas

2016-12-01

Web technologies are quickly evolving and are gaining in computational power and flexibility, allowing for a paradigm shift in the field of Data Acquisition (DAQ) systems design. Modern web browsers offer the possibility to create intricate user interfaces and are able to process and render complex data. Furthermore, new web standards such as WebSockets allow for fast real-time communication between the server and the user with minimal overhead. Those improvements make it possible to move the control and monitoring operations from the back-end servers directly to the user and to the front-end electronics, thus reducing the complexity of the data acquisition chain. Moreover, web-based DAQ systems offer greater flexibility, accessibility, and maintainability on the user side than traditional applications which often lack portability and ease of use. As proof of concept, we implemented a simplified DAQ system on a mid-range Spartan6 Field Programmable Gate Array (FPGA) development board coupled to a digital front-end readout chip. The system is connected to the Internet and can be accessed from any web browser. It is composed of custom code to control the front-end readout and of a dual soft-core Microblaze processor to communicate with the client.

A multitasking, multisinked, multiprocessor data acquisition front end

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fox, R.; Au, R.; Molen, A.V.

1989-10-01

The authors have developed a generalized data acquisition front end system which is based on MC68020 processors running a commercial real time kernel (rhoSOS), and implemented primarily in a high level language (C). This system has been attached to the back end on-line computing system at NSCL via our high performance ETHERNET protocol. Data may be simultaneously sent to any number of back end systems. Fixed fraction sampling along links to back end computing is also supported. A nonprocedural program generator simplifies the development of experiment specific code.

Information adaptive system of NEEDS. [of NASA End to End Data System

NASA Technical Reports Server (NTRS)

Howle, W. M., Jr.; Kelly, W. L.

1979-01-01

The NASA End-to-End Data System (NEEDS) program was initiated by NASA to improve significantly the state of the art in acquisition, processing, and distribution of space-acquired data for the mid-1980s and beyond. The information adaptive system (IAS) is a program element under NEEDS Phase II which addresses sensor specific processing on board the spacecraft. The IAS program is a logical first step toward smart sensors, and IAS developments - particularly the system components and key technology improvements - are applicable to future smart efforts. The paper describes the design goals and functional elements of the IAS. In addition, the schedule for IAS development and demonstration is discussed.

Determination of end point of primary drying in freeze-drying process control.

PubMed

Patel, Sajal M; Doen, Takayuki; Pikal, Michael J

2010-03-01

Freeze-drying is a relatively expensive process requiring long processing time, and hence one of the key objectives during freeze-drying process development is to minimize the primary drying time, which is the longest of the three steps in freeze-drying. However, increasing the shelf temperature into secondary drying before all of the ice is removed from the product will likely cause collapse or eutectic melt. Thus, from product quality as well as process economics standpoint, it is very critical to detect the end of primary drying. Experiments were conducted with 5% mannitol and 5% sucrose as model systems. The apparent end point of primary drying was determined by comparative pressure measurement (i.e., Pirani vs. MKS Baratron), dew point, Lyotrack (gas plasma spectroscopy), water concentration from tunable diode laser absorption spectroscopy, condenser pressure, pressure rise test (manometric temperature measurement or variations of this method), and product thermocouples. Vials were pulled out from the drying chamber using a sample thief during late primary and early secondary drying to determine percent residual moisture either gravimetrically or by Karl Fischer, and the cake structure was determined visually for melt-back, collapse, and retention of cake structure at the apparent end point of primary drying (i.e., onset, midpoint, and offset). By far, the Pirani is the best choice of the methods tested for evaluation of the end point of primary drying. Also, it is a batch technique, which is cheap, steam sterilizable, and easy to install without requiring any modification to the existing dryer.

40 CFR 63.495 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2011 CFR

2011-07-01

... current process operating conditions. (iii) Design analysis based on accepted chemical engineering... quantity are production records, measurement of stream characteristics, and engineering calculations. (5...-end process operations using engineering assessment. Engineering assessment includes, but is not...

40 CFR 63.495 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2013 CFR

2013-07-01

... current process operating conditions. (iii) Design analysis based on accepted chemical engineering... quantity are production records, measurement of stream characteristics, and engineering calculations. (5...-end process operations using engineering assessment. Engineering assessment includes, but is not...

40 CFR 63.495 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2014 CFR

2014-07-01

... current process operating conditions. (iii) Design analysis based on accepted chemical engineering... quantity are production records, measurement of stream characteristics, and engineering calculations. (5...-end process operations using engineering assessment. Engineering assessment includes, but is not...

40 CFR 63.495 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2012 CFR

2012-07-01

... current process operating conditions. (iii) Design analysis based on accepted chemical engineering... quantity are production records, measurement of stream characteristics, and engineering calculations. (5...-end process operations using engineering assessment. Engineering assessment includes, but is not...

Back pain's association with vertebral end-plate signal changes in sciatica.

PubMed

el Barzouhi, Abdelilah; Vleggeert-Lankamp, Carmen L A M; van der Kallen, Bas F; Lycklama à Nijeholt, Geert J; van den Hout, Wilbert B; Koes, Bart W; Peul, Wilco C

2014-02-01

Patients with sciatica frequently experience disabling back pain. One of the proposed causes for back pain is vertebral end-plate signal changes (VESC) as visualized by magnetic resonance imaging (MRI). To report on VESC findings, changes of VESC findings over time, and the correlation between VESC and disabling back pain in patients with sciatica. A randomized clinical trial with 1 year of follow-up. Patients with 6 to 12 weeks of sciatica who participated in a multicenter, randomized clinical trial comparing an early surgery strategy with prolonged conservative care with surgery if needed. Patients were assessed by means of the 100-mm visual analog scale (VAS) for back pain (with 0 representing no pain and 100 the worst pain ever experienced) at baseline and 1 year. Disabling back pain was defined as a VAS score of at least 40 mm. Patients underwent MRI both at baseline and after 1 year follow-up. Presence and change of VESC was correlated with disabling back pain using chi-square tests and logistic regression analysis. At baseline, 39% of patients had disabling back pain. Of the patients with VESC at baseline, 40% had disabling back pain compared with 38% of the patients with no VESC (p=.67). The prevalence of type 1 VESC increased from 1% at baseline to 35% 1 year later in the surgical group compared with an increase from 3% to 11% in the conservative group. The prevalence of type 2 VESC decreased from 40% to 29% in the surgical group while remaining almost stable in the conservative group at 41%. The prevalence of disabling back pain at 1 year was 12% in patients with no VESC at 1 year, 16% in patients with type 1 VESC, 11% in patients with type 2 VESC, and 3% in patients with both types 1 and 2 VESC (p=.36). Undergoing surgery was associated with increase in the extent of VESC (odds ratio [OR], 8.6; 95% confidence interval [CI], 4.7-15.7; p<.001). Patients who showed an increase in the extent of VESC after 1 year did not significantly report more disabling

Innovative strategy for effective critical laboratory result management: end-to-end process using automation and manual call centre.

PubMed

Ti, Lian Kah; Ang, Sophia Bee Leng; Saw, Sharon; Sethi, Sunil Kumar; Yip, James W L

2012-08-01

Timely reporting and acknowledgement are crucial steps in critical laboratory results (CLR) management. The authors previously showed that an automated pathway incorporating short messaging system (SMS) texts, auto-escalation, and manual telephone back-up improved the rate and speed of physician acknowledgement compared with manual telephone calling alone. This study investigated if it also improved the rate and speed of physician intervention to CLR and whether utilising the manual back-up affected intervention rates. Data from seven audits between November 2007 and January 2011 were analysed. These audits were carried out to assess the robustness of CLR reporting process in the authors' institution. Comparisons were made in the rate and speed of acknowledgement and intervention between the audits performed before and after automation. Using the automation audits, the authors compared intervention data between communication with SMS only and when manual intervention was required. 1680 CLR were reported during the audit periods. Automation improved the rate (100% vs 84.2%; p<0.001) and speed (median 12 min vs 23 min; p<0.001) of CLR acknowledgement. It also improved the rate (93.7% vs 84.0%, p<0.001) and speed (median 21 min vs 109 min; p<0.001) of CLR intervention. From the automation audits, the use of SMS only did not improve physician intervention rates. The automated communication pathway improved physician intervention rate and time in tandem with improved acknowledgement rate and time when compared with manual telephone calling. The use of manual intervention to augment automation did not adversely affect physician intervention rate, implying that an end-to-end pathway was more important than automation alone.

End-to-end System Performance Simulation: A Data-Centric Approach

NASA Astrophysics Data System (ADS)

Guillaume, Arnaud; Laffitte de Petit, Jean-Luc; Auberger, Xavier

2013-08-01

In the early times of space industry, the feasibility of Earth observation missions was directly driven by what could be achieved by the satellite. It was clear to everyone that the ground segment would be able to deal with the small amount of data sent by the payload. Over the years, the amounts of data processed by the spacecrafts have been increasing drastically, leading to put more and more constraints on the ground segment performances - and in particular on timeliness. Nowadays, many space systems require high data throughputs and short response times, with information coming from multiple sources and involving complex algorithms. It has become necessary to perform thorough end-to-end analyses of the full system in order to optimise its cost and efficiency, but even sometimes to assess the feasibility of the mission. This paper presents a novel framework developed by Astrium Satellites in order to meet these needs of timeliness evaluation and optimisation. This framework, named ETOS (for “End-to-end Timeliness Optimisation of Space systems”), provides a modelling process with associated tools, models and GUIs. These are integrated thanks to a common data model and suitable adapters, with the aim of building suitable space systems simulators of the full end-to-end chain. A big challenge of such environment is to integrate heterogeneous tools (each one being well-adapted to part of the chain) into a relevant timeliness simulation.

Back-Arc Opening in the Western End of the Okinawa Trough Revealed From GNSS/Acoustic Measurements

NASA Astrophysics Data System (ADS)

Chen, Horng-Yue; Ikuta, Ryoya; Lin, Cheng-Horng; Hsu, Ya-Ju; Kohmi, Takeru; Wang, Chau-Chang; Yu, Shui-Beih; Tu, Yoko; Tsujii, Toshiaki; Ando, Masataka

2018-01-01

We measured seafloor movement using a Global Navigation Satellite Systems (GNSS)/Acoustic technique at the south of the rifting valley in the western end of the Okinawa Trough back-arc basin, 60 km east of northeastern corner of Taiwan. The horizontal position of the seafloor benchmark, measured eight times between July 2012 and May 2016, showed a southeastward movement suggesting a back-arc opening of the Okinawa Trough. The average velocity of the seafloor benchmark shows a block motion together with Yonaguni Island. The westernmost part of the Ryukyu Arc rotates clockwise and is pulled apart from the Taiwan Island, which should cause the expansion of the Yilan Plain, Taiwan. Comparing the motion of the seafloor benchmark with adjacent seismicity, we suggest a gentle episodic opening of the rifting valley accompanying a moderate seismic activation, which differs from the case in the segment north off-Yonaguni Island where a rapid dyke intrusion occurs with a significant seismic activity.

Indium-oxide nanoparticles for RRAM devices compatible with CMOS back-end-off-line

NASA Astrophysics Data System (ADS)

León Pérez, Edgar A. A.; Guenery, Pierre-Vincent; Abouzaid, Oumaïma; Ayadi, Khaled; Brottet, Solène; Moeyaert, Jérémy; Labau, Sébastien; Baron, Thierry; Blanchard, Nicholas; Baboux, Nicolas; Militaru, Liviu; Souifi, Abdelkader

2018-05-01

We report on the fabrication and characterization of Resistive Random Access Memory (RRAM) devices based on nanoparticles in MIM structures. Our approach is based on the use of indium oxide (In2O3) nanoparticles embedded in a dielectric matrix using CMOS-full-compatible fabrication processes in view of back-end-off-line integration for non-volatile memory (NVM) applications. A bipolar switching behavior has been observed using current-voltage measurements (I-V) for all devices. Very high ION/IOFF ratios have been obtained up to 108. Our results provide insights for further integration of In2O3 nanoparticles-based devices for NVM applications. He is currently a Postdoctoral Researcher in the Institute of Nanotechnologies of Lyon (INL), INSA de Lyon, France, in the Electronics Department. His current research include indium oxide nanoparticles for non-volatile memory applications, and the integrations of these devices in CMOS BEOL.

Evaluation of NASA's end-to-end data systems using DSDS+

NASA Technical Reports Server (NTRS)

Rouff, Christopher; Davenport, William; Message, Philip

1994-01-01

The Data Systems Dynamic Simulator (DSDS+) is a software tool being developed by the authors to evaluate candidate architectures for NASA's end-to-end data systems. Via modeling and simulation, we are able to quickly predict the performance characteristics of each architecture, to evaluate 'what-if' scenarios, and to perform sensitivity analyses. As such, we are using modeling and simulation to help NASA select the optimal system configuration, and to quantify the performance characteristics of this system prior to its delivery. This paper is divided into the following six sections: (1) The role of modeling and simulation in the systems engineering process. In this section, we briefly describe the different types of results obtained by modeling each phase of the systems engineering life cycle, from concept definition through operations and maintenance; (2) Recent applications of DSDS+. In this section, we describe ongoing applications of DSDS+ in support of the Earth Observing System (EOS), and we present some of the simulation results generated of candidate system designs. So far, we have modeled individual EOS subsystems (e.g. the Solid State Recorders used onboard the spacecraft), and we have also developed an integrated model of the EOS end-to-end data processing and data communications systems (from the payloads onboard to the principle investigator facilities on the ground); (3) Overview of DSDS+. In this section we define what a discrete-event model is, and how it works. The discussion is presented relative to the DSDS+ simulation tool that we have developed, including it's run-time optimization algorithms that enables DSDS+ to execute substantially faster than comparable discrete-event simulation tools; (4) Summary. In this section, we summarize our findings and 'lessons learned' during the development and application of DSDS+ to model NASA's data systems; (5) Further Information; and (6) Acknowledgements.

Lithium isotopic systematics of submarine vent fluids from arc and back-arc hydrothermal systems in the western Pacific

NASA Astrophysics Data System (ADS)

Araoka, Daisuke; Nishio, Yoshiro; Gamo, Toshitaka; Yamaoka, Kyoko; Kawahata, Hodaka

2016-10-01

The Li concentration and isotopic composition (δ7Li) in submarine vent fluids are important for oceanic Li budget and potentially useful for investigating hydrothermal systems deep under the seafloor because hydrothermal vent fluids are highly enriched in Li relative to seawater. Although Li isotopic geochemistry has been studied at mid-ocean-ridge (MOR) hydrothermal sites, in arc and back-arc settings Li isotopic composition has not been systematically investigated. Here we determined the δ7Li and 87Sr/86Sr values of 11 end-member fluids from 5 arc and back-arc hydrothermal systems in the western Pacific and examined Li behavior during high-temperature water-rock interactions in different geological settings. In sediment-starved hydrothermal systems (Manus Basin, Izu-Bonin Arc, Mariana Trough, and North Fiji Basin), the Li concentrations (0.23-1.30 mmol/kg) and δ7Li values (+4.3‰ to +7.2‰) of the end-member fluids are explained mainly by dissolution-precipitation model during high-temperature seawater-rock interactions at steady state. Low Li concentrations are attributable to temperature-related apportioning of Li in rock into the fluid phase and phase separation process. Small variation in Li among MOR sites is probably caused by low-temperature alteration process by diffusive hydrothermal fluids under the seafloor. In contrast, the highest Li concentrations (3.40-5.98 mmol/kg) and lowest δ7Li values (+1.6‰ to +2.4‰) of end-member fluids from the Okinawa Trough demonstrate that the Li is predominantly derived from marine sediments. The variation of Li in sediment-hosted sites can be explained by the differences in degree of hydrothermal fluid-sediment interactions associated with the thickness of the marine sediment overlying these hydrothermal sites.

Poly(ADP-ribose)polymerases are involved in microhomology mediated back-up non-homologous end joining in Arabidopsis thaliana.

PubMed

Jia, Qi; den Dulk-Ras, Amke; Shen, Hexi; Hooykaas, Paul J J; de Pater, Sylvia

2013-07-01

Besides the KU-dependent classical non-homologous end-joining (C-NHEJ) pathway, an alternative NHEJ pathway first identified in mammalian systems, which is often called the back-up NHEJ (B-NHEJ) pathway, was also found in plants. In mammalian systems PARP was found to be one of the essential components in B-NHEJ. Here we investigated whether PARP1 and PARP2 were also involved in B-NHEJ in Arabidopsis. To this end Arabidopsis parp1, parp2 and parp1parp2 (p1p2) mutants were isolated and functionally characterized. The p1p2 double mutant was crossed with the C-NHEJ ku80 mutant resulting in the parp1parp2ku80 (p1p2k80) triple mutant. As expected, because of their role in single strand break repair (SSBR) and base excision repair (BER), the p1p2 and p1p2k80 mutants were shown to be sensitive to treatment with the DNA damaging agent MMS. End-joining assays in cell-free leaf protein extracts of the different mutants using linear DNA substrates with different ends reflecting a variety of double strand breaks were performed. The results showed that compatible 5'-overhangs were accurately joined in all mutants, that KU80 protected the ends preventing the formation of large deletions and that PARP proteins were involved in microhomology mediated end joining (MMEJ), one of the characteristics of B-NHEJ.

Glycation inhibitors extend yeast chronological lifespan by reducing advanced glycation end products and by back regulation of proteins involved in mitochondrial respiration.

PubMed

Kazi, Rubina S; Banarjee, Reema M; Deshmukh, Arati B; Patil, Gouri V; Jagadeeshaprasad, Mashanipalya G; Kulkarni, Mahesh J

2017-03-06

Advanced Glycation End products (AGEs) are implicated in aging process. Thus, reducing AGEs by using glycation inhibitors may help in attenuating the aging process. In this study using Saccharomyces cerevisiae yeast system, we show that Aminoguanidine (AMG), a well-known glycation inhibitor, decreases the AGE modification of proteins in non-calorie restriction (NR) (2% glucose) and extends chronological lifespan (CLS) similar to that of calorie restriction (CR) condition (0.5% glucose). Proteomic analysis revealed that AMG back regulates the expression of differentially expressed proteins especially those involved in mitochondrial respiration in NR condition, suggesting that it switches metabolism from fermentation to respiration, mimicking CR. AMG induced back regulation of differentially expressed proteins could be possibly due to its chemical effect or indirectly by glycation inhibition. To delineate this, Metformin (MET), a structural analog of AMG and a mild glycation inhibitor and Hydralazine (HYD), another potent glycation inhibitor but not structural analog of AMG were used. HYD was more effective than MET in mimicking AMG suggesting that glycation inhibition was responsible for restoration of differentially expressed proteins. Thus glycation inhibitors particularly AMG, HYD and MET extend yeast CLS by reducing AGEs, modulating the expression of proteins involved in mitochondrial respiration and possibly by scavenging glucose. This study reports the role of glycation in aging process. In the non-caloric restriction condition, carbohydrates such as glucose promote protein glycation and reduce CLS. While, the inhibitors of glycation such as AMG, HYD, MET mimic the caloric restriction condition by back regulating deregulated proteins involved in mitochondrial respiration which could facilitate shift of metabolism from fermentation to respiration and extend yeast CLS. These findings suggest that glycation inhibitors can be potential molecules that can be used

Silicon nitride back-end optics for biosensor applications

NASA Astrophysics Data System (ADS)

Romero-García, Sebastian; Merget, Florian; Zhong, Frank C.; Finkelstein, Hod; Witzens, Jeremy

2013-05-01

Silicon nitride (SiN) is a promising candidate material for becoming a standard high-performance solution for integrated biophotonics applications in the visible spectrum. As a key feature, its compatibility with the complementary-oxidemetal- semiconductor (CMOS) technology permits cost reduction at large manufacturing volumes that is particularly advantageous for manufacturing consumables. In this work, we show that the back-end deposition of a thin SiN film enables the large light-cladding interaction desirable for biosensing applications while the refractive index contrast of the technology (Δn ≍ 0.5) also enables a considerable level of integration with reduced waveguide bend radii. Design and experimental validation also show that several advantages are derived from the moderate SiN/SiO2 refractive index contrast, such as lower scattering losses in interconnection waveguides and relaxed tolerances to fabrication imperfections as compared to higher refractive index contrast material systems. As a drawback, a moderate refractive index contrast also makes the implementation of compact grating couplers more challenging, due to the fact that only a relatively weak scattering strength can be achieved. Thereby, the beam diffracted by the grating tends to be rather large and consequently exhibit stringent angular alignment tolerances. Here, we experimentally demonstrate how a proper design of the bottom and top cladding oxide thicknesses allows reduction of the full-width at half maximum (FWHM) and alleviates this problem. Additionally, the inclusion of a CMOS-compatible AlCu/TiN bottom reflector further decreases the FWHM and increases the coupling efficiency. Finally, we show that focusing grating designs greatly reduce the device footprint without penalizing the device metrics.

HTS flywheel energy storage system with rotor shaft stabilized by feed-back control of armature currents of motor-generator

NASA Astrophysics Data System (ADS)

Tsukamoto, O.; Utsunomiya, A.

2007-10-01

We propose an HTS bulk bearing flywheel energy system (FWES) with rotor shaft stabilization system using feed-back control of the armature currents of the motor-generator. In the proposed system the rotor shift has a pivot bearing at one end of the shaft and an HTS bulk bearing (SMB) at the other end. The fluctuation of the rotor shaft with SMB is damped by feed-back control of the armature currents of the motor-generator sensing the position of the rotor shaft. The method has merits that the fluctuations are damped without active control magnet bearings and extra devices which may deteriorate the energy storage efficiency and need additional costs. The principle of the method was demonstrated by an experiment using a model permanent magnet motor.

End-to-end communication test on variable length packet structures utilizing AOS testbed

NASA Technical Reports Server (NTRS)

Miller, Warner H.; Sank, V.; Fong, Wai; Miko, J.; Powers, M.; Folk, John; Conaway, B.; Michael, K.; Yeh, Pen-Shu

1994-01-01

This paper describes a communication test, which successfully demonstrated the transfer of losslessly compressed images in an end-to-end system. These compressed images were first formatted into variable length Consultative Committee for Space Data Systems (CCSDS) packets in the Advanced Orbiting System Testbed (AOST). The CCSDS data Structures were transferred from the AOST to the Radio Frequency Simulations Operations Center (RFSOC), via a fiber optic link, where data was then transmitted through the Tracking and Data Relay Satellite System (TDRSS). The received data acquired at the White Sands Complex (WSC) was transferred back to the AOST where the data was captured and decompressed back to the original images. This paper describes the compression algorithm, the AOST configuration, key flight components, data formats, and the communication link characteristics and test results.

Back-Up/ Peak Shaving Fuel Cell System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Staudt, Rhonda L.

2008-05-28

This Final Report covers the work executed by Plug Power from 8/11/03 – 10/31/07 statement of work for Topic 2: advancing the state of the art of fuel cell technology with the development of a new generation of commercially viable, stationary, Back-up/Peak-Shaving fuel cell systems, the GenCore II. The Program cost was $7.2 M with the Department of Energy share being $3.6M and Plug Power’s share being $3.6 M. The Program started in August of 2003 and was scheduled to end in January of 2006. The actual program end date was October of 2007. A no cost extension was grated.more » The Department of Energy barriers addressed as part of this program are: Technical Barriers for Distributed Generation Systems: o Durability o Power Electronics o Start up time Technical Barriers for Fuel Cell Components: o Stack Material and Manufacturing Cost o Durability o Thermal and water management Background The next generation GenCore backup fuel cell system to be designed, developed and tested by Plug Power under the program is the first, mass-manufacturable design implementation of Plug Power’s GenCore architected platform targeted for battery and small generator replacement applications in the telecommunications, broadband and UPS markets. The next generation GenCore will be a standalone, H2 in-DC-out system. In designing the next generation GenCore specifically for the telecommunications market, Plug Power is teaming with BellSouth Telecommunications, Inc., a leading industry end user. The final next generation GenCore system is expected to represent a market-entry, mass-manufacturable and economically viable design. The technology will incorporate: • A cost-reduced, polymer electrolyte membrane (PEM) fuel cell stack tailored to hydrogen fuel use • An advanced electrical energy storage system • A modular, scalable power conditioning system tailored to market requirements • A scaled-down, cost-reduced balance of plant (BOP) • Network Equipment Building Standards

End-to-End Data System Architecture for the Space Station Biological Research Project

NASA Technical Reports Server (NTRS)

Mian, Arshad; Scimemi, Sam; Adeni, Kaiser; Picinich, Lou; Ramos, Rubin (Technical Monitor)

1998-01-01

The Space Station Biological Research Project (SSBRP) Is developing hardware referred to as the "facility" for providing life sciences research capability on the International Space Station. This hardware includes several biological specimen habitats, habitat holding racks, a centrifuge and a glovebox. An SSBRP end to end data system architecture has been developed to allow command and control of the facility from the ground, either with crew assistance or autonomously. The data system will be capable of handling commands, sensor data, and video from multiple cameras. The data will traverse through several onboard and ground networks and processing entities including the SSBRP and Space Station onboard and ground data systems. A large number of onboard and ground (,entities of the data system are being developed by the Space Station Program, other NASA centers and the International Partners. The SSBRP part of the system which includes the habitats, holding racks, and the ground operations center, User Operations Facility (UOF) will be developed by a multitude of geographically distributed development organizations. The SSBRP has the responsibility to define the end to end data and communications systems to make the interfaces manageable and verifiable with multiple contractors with widely varying development constraints and schedules. This paper provides an overview of the SSBRP end-to-end data system. Specifically, it describes the hardware, software and functional interactions of individual systems, and interface requirements among various entities of the end-to-end system.

Large scale integration of graphene transistors for potential applications in the back end of the line

NASA Astrophysics Data System (ADS)

Smith, A. D.; Vaziri, S.; Rodriguez, S.; Östling, M.; Lemme, M. C.

2015-06-01

A chip to wafer scale, CMOS compatible method of graphene device fabrication has been established, which can be integrated into the back end of the line (BEOL) of conventional semiconductor process flows. In this paper, we present experimental results of graphene field effect transistors (GFETs) which were fabricated using this wafer scalable method. The carrier mobilities in these transistors reach up to several hundred cm2 V-1 s-1. Further, these devices exhibit current saturation regions similar to graphene devices fabricated using mechanical exfoliation. The overall performance of the GFETs can not yet compete with record values reported for devices based on mechanically exfoliated material. Nevertheless, this large scale approach is an important step towards reliability and variability studies as well as optimization of device aspects such as electrical contacts and dielectric interfaces with statistically relevant numbers of devices. It is also an important milestone towards introducing graphene into wafer scale process lines.

Flank wears Simulation by using back propagation neural network when cutting hardened H-13 steel in CNC End Milling

NASA Astrophysics Data System (ADS)

Hazza, Muataz Hazza F. Al; Adesta, Erry Y. T.; Riza, Muhammad

2013-12-01

High speed milling has many advantages such as higher removal rate and high productivity. However, higher cutting speed increase the flank wear rate and thus reducing the cutting tool life. Therefore estimating and predicting the flank wear length in early stages reduces the risk of unaccepted tooling cost. This research presents a neural network model for predicting and simulating the flank wear in the CNC end milling process. A set of sparse experimental data for finish end milling on AISI H13 at hardness of 48 HRC have been conducted to measure the flank wear length. Then the measured data have been used to train the developed neural network model. Artificial neural network (ANN) was applied to predict the flank wear length. The neural network contains twenty hidden layer with feed forward back propagation hierarchical. The neural network has been designed with MATLAB Neural Network Toolbox. The results show a high correlation between the predicted and the observed flank wear which indicates the validity of the models.

Effectiveness of back-to-back testing

NASA Technical Reports Server (NTRS)

Vouk, Mladen A.; Mcallister, David F.; Eckhardt, David E.; Caglayan, Alper; Kelly, John P. J.

1987-01-01

Three models of back-to-back testing processes are described. Two models treat the case where there is no intercomponent failure dependence. The third model describes the more realistic case where there is correlation among the failure probabilities of the functionally equivalent components. The theory indicates that back-to-back testing can, under the right conditions, provide a considerable gain in software reliability. The models are used to analyze the data obtained in a fault-tolerant software experiment. It is shown that the expected gain is indeed achieved, and exceeded, provided the intercomponent failure dependence is sufficiently small. However, even with the relatively high correlation the use of several functionally equivalent components coupled with back-to-back testing may provide a considerable reliability gain. Implications of this finding are that the multiversion software development is a feasible and cost effective approach to providing highly reliable software components intended for fault-tolerant software systems, on condition that special attention is directed at early detection and elimination of correlated faults.

Camera calibration based on the back projection process

NASA Astrophysics Data System (ADS)

Gu, Feifei; Zhao, Hong; Ma, Yueyang; Bu, Penghui

2015-12-01

Camera calibration plays a crucial role in 3D measurement tasks of machine vision. In typical calibration processes, camera parameters are iteratively optimized in the forward imaging process (FIP). However, the results can only guarantee the minimum of 2D projection errors on the image plane, but not the minimum of 3D reconstruction errors. In this paper, we propose a universal method for camera calibration, which uses the back projection process (BPP). In our method, a forward projection model is used to obtain initial intrinsic and extrinsic parameters with a popular planar checkerboard pattern. Then, the extracted image points are projected back into 3D space and compared with the ideal point coordinates. Finally, the estimation of the camera parameters is refined by a non-linear function minimization process. The proposed method can obtain a more accurate calibration result, which is more physically useful. Simulation and practical data are given to demonstrate the accuracy of the proposed method.

Advanced end-to-end fiber optic sensing systems for demanding environments

NASA Astrophysics Data System (ADS)

Black, Richard J.; Moslehi, Behzad

2010-09-01

Optical fibers are small-in-diameter, light-in-weight, electromagnetic-interference immune, electrically passive, chemically inert, flexible, embeddable into different materials, and distributed-sensing enabling, and can be temperature and radiation tolerant. With appropriate processing and/or packaging, they can be very robust and well suited to demanding environments. In this paper, we review a range of complete end-to-end fiber optic sensor systems that IFOS has developed comprising not only (1) packaged sensors and mechanisms for integration with demanding environments, but (2) ruggedized sensor interrogators, and (3) intelligent decision aid algorithms software systems. We examine the following examples: " Fiber Bragg Grating (FBG) optical sensors systems supporting arrays of environmentally conditioned multiplexed FBG point sensors on single or multiple optical fibers: In conjunction with advanced signal processing, decision aid algorithms and reasoners, FBG sensor based structural health monitoring (SHM) systems are expected to play an increasing role in extending the life and reducing costs of new generations of aerospace systems. Further, FBG based structural state sensing systems have the potential to considerably enhance the performance of dynamic structures interacting with their environment (including jet aircraft, unmanned aerial vehicles (UAVs), and medical or extravehicular space robots). " Raman based distributed temperature sensing systems: The complete length of optical fiber acts as a very long distributed sensor which may be placed down an oil well or wrapped around a cryogenic tank.

Differences in end-range lumbar flexion during slumped sitting and forward bending between low back pain subgroups and genders

PubMed Central

Hoffman, Shannon L.; Johnson, Molly B.; Zou, Dequan; Van Dillen, Linda R.

2012-01-01

Patterns of lumbar posture and motion are associated with low back pain (LBP). Research suggests LBP subgroups demonstrate different patterns during common tasks. This study assessed differences in end-range lumbar flexion during two tasks between two LBP subgroups classified according to the Movement System Impairment model. Additionally, the impact of gender differences on subgroup differences was assessed. Kinematic data were collected. Subjects in the Rotation (Rot) and Rotation with Extension (RotExt) LBP subgroups were asked to sit slumped and bend forward from standing. Lumbar end-range flexion was calculated. Subjects reported symptom behavior during each test. Compared to the RotExt subgroup, the Rot subgroup demonstrated greater end-range lumbar flexion during slumped sitting and a trend towards greater end-range lumbar flexion with forward bending. Compared to females, males demonstrated greater end-range lumbar flexion during slumped sitting and forward bending. A greater proportion of people in the Rot subgroup reported symptoms with each test compared to the RotExt subgroup. Males and females were equally likely to report symptoms with each test. Gender differences were not responsible for LBP subgroup differences. Subgrouping people with LBP provides insight into differences in lumbar motion within the LBP population. Results suggesting potential consistent differences across flexion-related tasks support the presence of stereotypical movement patterns that are related to LBP. PMID:22261650

Linear Back-Drive Differentials

NASA Technical Reports Server (NTRS)

Waydo, Peter

2003-01-01

Linear back-drive differentials have been proposed as alternatives to conventional gear differentials for applications in which there is only limited rotational motion (e.g., oscillation). The finite nature of the rotation makes it possible to optimize a linear back-drive differential in ways that would not be possible for gear differentials or other differentials that are required to be capable of unlimited rotation. As a result, relative to gear differentials, linear back-drive differentials could be more compact and less massive, could contain fewer complex parts, and could be less sensitive to variations in the viscosities of lubricants. Linear back-drive differentials would operate according to established principles of power ball screws and linear-motion drives, but would utilize these principles in an innovative way. One major characteristic of such mechanisms that would be exploited in linear back-drive differentials is the possibility of designing them to drive or back-drive with similar efficiency and energy input: in other words, such a mechanism can be designed so that a rotating screw can drive a nut linearly or the linear motion of the nut can cause the screw to rotate. A linear back-drive differential (see figure) would include two collinear shafts connected to two parts that are intended to engage in limited opposing rotations. The linear back-drive differential would also include a nut that would be free to translate along its axis but not to rotate. The inner surface of the nut would be right-hand threaded at one end and left-hand threaded at the opposite end to engage corresponding right- and left-handed threads on the shafts. A rotation and torque introduced into the system via one shaft would drive the nut in linear motion. The nut, in turn, would back-drive the other shaft, creating a reaction torque. Balls would reduce friction, making it possible for the shaft/nut coupling on each side to operate with 90 percent efficiency.

BrainIACS: a system for web-based medical image processing

NASA Astrophysics Data System (ADS)

Kishore, Bhaskar; Bazin, Pierre-Louis; Pham, Dzung L.

2009-02-01

We describe BrainIACS, a web-based medical image processing system that permits and facilitates algorithm developers to quickly create extensible user interfaces for their algorithms. Designed to address the challenges faced by algorithm developers in providing user-friendly graphical interfaces, BrainIACS is completely implemented using freely available, open-source software. The system, which is based on a client-server architecture, utilizes an AJAX front-end written using the Google Web Toolkit (GWT) and Java Servlets running on Apache Tomcat as its back-end. To enable developers to quickly and simply create user interfaces for configuring their algorithms, the interfaces are described using XML and are parsed by our system to create the corresponding user interface elements. Most of the commonly found elements such as check boxes, drop down lists, input boxes, radio buttons, tab panels and group boxes are supported. Some elements such as the input box support input validation. Changes to the user interface such as addition and deletion of elements are performed by editing the XML file or by using the system's user interface creator. In addition to user interface generation, the system also provides its own interfaces for data transfer, previewing of input and output files, and algorithm queuing. As the system is programmed using Java (and finally Java-script after compilation of the front-end code), it is platform independent with the only requirements being that a Servlet implementation be available and that the processing algorithms can execute on the server platform.

40 CFR 63.498 - Back-end process provisions-recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... be the crumb rubber dry weight of the rubber leaving the stripper. (iv) The organic HAP content of... stripper. (B) For solution processes, this quantity shall be the crumb rubber dry weight of the crumb rubber leaving the stripper. (iii) The hourly average of all stripper parameter results; (iv) If one or...

Feed-back between geriatric syndromes: general system theory in geriatrics.

PubMed

Musso, Carlos G; Núñez, Juan F Macías

2006-01-01

Geriatrics has described three entities: confusional syndrome, incontinente and gait disorders, calling them geriatric giants. Aging process also induces changes in renal physiology such as glomerular filtration rate reduction, and alteration in water and electrolytes handling. These ageing renal changes have been named as nephrogeriatric giants. These two groups of giants, geriatric and nephrogeriatric, can predispose and potentiate each other leading old people to fatal outcomes. These phenomenon of feed-back between these geriatric syndromes has its roots in the loss of complexity that the ageing process has. Complexity means that all the body systems work harmoniously. The process of senescence weakens this coordination among systems undermining complexity and making the old person frail.

A method of Modelling and Simulating the Back-to-Back Modular Multilevel Converter HVDC Transmission System

NASA Astrophysics Data System (ADS)

Wang, Lei; Fan, Youping; Zhang, Dai; Ge, Mengxin; Zou, Xianbin; Li, Jingjiao

2017-09-01

This paper proposes a method to simulate a back-to-back modular multilevel converter (MMC) HVDC transmission system. In this paper we utilize an equivalent networks to simulate the dynamic power system. Moreover, to account for the performance of converter station, core components of model of the converter station gives a basic model of simulation. The proposed method is applied to an equivalent real power system.

Backing collisions: a study of drivers' eye and backing behaviour using combined rear-view camera and sensor systems.

PubMed

Hurwitz, David S; Pradhan, Anuj; Fisher, Donald L; Knodler, Michael A; Muttart, Jeffrey W; Menon, Rajiv; Meissner, Uwe

2010-04-01

Backing crash injures can be severe; approximately 200 of the 2,500 reported injuries of this type per year to children under the age of 15 years result in death. Technology for assisting drivers when backing has limited success in preventing backing crashes. Two questions are addressed: Why is the reduction in backing crashes moderate when rear-view cameras are deployed? Could rear-view cameras augment sensor systems? 46 drivers (36 experimental, 10 control) completed 16 parking trials over 2 days (eight trials per day). Experimental participants were provided with a sensor camera system, controls were not. Three crash scenarios were introduced. Parking facility at UMass Amherst, USA. 46 drivers (33 men, 13 women) average age 29 years, who were Massachusetts residents licensed within the USA for an average of 9.3 years. Interventions Vehicles equipped with a rear-view camera and sensor system-based parking aid. Subject's eye fixations while driving and researcher's observation of collision with objects during backing. Only 20% of drivers looked at the rear-view camera before backing, and 88% of those did not crash. Of those who did not look at the rear-view camera before backing, 46% looked after the sensor warned the driver. This study indicates that drivers not only attend to an audible warning, but will look at a rear-view camera if available. Evidence suggests that when used appropriately, rear-view cameras can mitigate the occurrence of backing crashes, particularly when paired with an appropriate sensor system.

The Need for Integrating the Back End of the Nuclear Fuel Cycle in the United States of America

DOE PAGES

Bonano, Evaristo J.; Kalinina, Elena A.; Swift, Peter N.

2018-02-26

Current practice for commercial spent nuclear fuel management in the United States of America (US) includes storage of spent fuel in both pools and dry storage cask systems at nuclear power plants. Most storage pools are filled to their operational capacity, and management of the approximately 2,200 metric tons of spent fuel newly discharged each year requires transferring older and cooler fuel from pools into dry storage. In the absence of a repository that can accept spent fuel for permanent disposal, projections indicate that the US will have approximately 134,000 metric tons of spent fuel in dry storage by mid-centurymore » when the last plants in the current reactor fleet are decommissioned. Current designs for storage systems rely on large dual-purpose (storage and transportation) canisters that are not optimized for disposal. Various options exist in the US for improving integration of management practices across the entire back end of the nuclear fuel cycle.« less

The Need for Integrating the Back End of the Nuclear Fuel Cycle in the United States of America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonano, Evaristo J.; Kalinina, Elena A.; Swift, Peter N.

Current practice for commercial spent nuclear fuel management in the United States of America (US) includes storage of spent fuel in both pools and dry storage cask systems at nuclear power plants. Most storage pools are filled to their operational capacity, and management of the approximately 2,200 metric tons of spent fuel newly discharged each year requires transferring older and cooler fuel from pools into dry storage. In the absence of a repository that can accept spent fuel for permanent disposal, projections indicate that the US will have approximately 134,000 metric tons of spent fuel in dry storage by mid-centurymore » when the last plants in the current reactor fleet are decommissioned. Current designs for storage systems rely on large dual-purpose (storage and transportation) canisters that are not optimized for disposal. Various options exist in the US for improving integration of management practices across the entire back end of the nuclear fuel cycle.« less

Backing collisions: a study of drivers’ eye and backing behaviour using combined rear-view camera and sensor systems

PubMed Central

Hurwitz, David S; Pradhan, Anuj; Fisher, Donald L; Knodler, Michael A; Muttart, Jeffrey W; Menon, Rajiv; Meissner, Uwe

2012-01-01

Context Backing crash injures can be severe; approximately 200 of the 2,500 reported injuries of this type per year to children under the age of 15 years result in death. Technology for assisting drivers when backing has limited success in preventing backing crashes. Objectives Two questions are addressed: Why is the reduction in backing crashes moderate when rear-view cameras are deployed? Could rear-view cameras augment sensor systems? Design 46 drivers (36 experimental, 10 control) completed 16 parking trials over 2 days (eight trials per day). Experimental participants were provided with a sensor camera system, controls were not. Three crash scenarios were introduced. Setting Parking facility at UMass Amherst, USA. Subjects 46 drivers (33 men, 13 women) average age 29 years, who were Massachusetts residents licensed within the USA for an average of 9.3 years. Interventions Vehicles equipped with a rear-view camera and sensor system-based parking aid. Main Outcome Measures Subject’s eye fixations while driving and researcher’s observation of collision with objects during backing. Results Only 20% of drivers looked at the rear-view camera before backing, and 88% of those did not crash. Of those who did not look at the rear-view camera before backing, 46% looked after the sensor warned the driver. Conclusions This study indicates that drivers not only attend to an audible warning, but will look at a rear-view camera if available. Evidence suggests that when used appropriately, rear-view cameras can mitigate the occurrence of backing crashes, particularly when paired with an appropriate sensor system. PMID:20363812

The Kepler End-to-End Model: Creating High-Fidelity Simulations to Test Kepler Ground Processing

NASA Technical Reports Server (NTRS)

Bryson, Stephen T.; Jenkins, Jon M.; Peters, Dan J.; Tenenbaum, Peter P.; Klaus, Todd C.; Gunter, Jay P.; Cote, Miles T.; Caldwell, Douglas A.

2010-01-01

The Kepler mission is designed to detect the transit of Earth-like planets around Sun-like stars by observing 100,000 stellar targets. Developing and testing the Kepler ground-segment processing system, in particular the data analysis pipeline, requires high-fidelity simulated data. This simulated data is provided by the Kepler End-to-End Model (ETEM). ETEM simulates the astrophysics of planetary transits and other phenomena, properties of the Kepler spacecraft and the format of the downlinked data. Major challenges addressed by ETEM include the rapid production of large amounts of simulated data, extensibility and maintainability.

Telecommunications end-to-end systems monitoring on TOPEX/Poseidon: Tools and techniques

NASA Technical Reports Server (NTRS)

Calanche, Bruno J.

1994-01-01

The TOPEX/Poseidon Project Satellite Performance Analysis Team's (SPAT) roles and responsibilities have grown to include functions that are typically performed by other teams on JPL Flight Projects. In particular, SPAT Telecommunication's role has expanded beyond the nominal function of monitoring, assessing, characterizing, and trending the spacecraft (S/C) RF/Telecom subsystem to one of End-to-End Information Systems (EEIS) monitoring. This has been accomplished by taking advantage of the spacecraft and ground data system structures and protocols. By processing both the received spacecraft telemetry minor frame ground generated CRC flags and NASCOM block poly error flags, bit error rates (BER) for each link segment can be determined. This provides the capability to characterize the separate link segments, determine science data recovery, and perform fault/anomaly detection and isolation. By monitoring and managing the links, TOPEX has successfully recovered approximately 99.9 percent of the science data with an integrity (BER) of better than 1 x 10(exp 8). This paper presents the algorithms used to process the above flags and the techniques used for EEIS monitoring.

30 CFR 75.1101-9 - Back-up water system.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Back-up water system. 75.1101-9 Section 75.1101-9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-9 Back-up water system...

30 CFR 75.1101-9 - Back-up water system.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Back-up water system. 75.1101-9 Section 75.1101-9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-9 Back-up water system...

30 CFR 75.1101-9 - Back-up water system.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Back-up water system. 75.1101-9 Section 75.1101-9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-9 Back-up water system...

30 CFR 75.1101-9 - Back-up water system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Back-up water system. 75.1101-9 Section 75.1101-9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-9 Back-up water system...

30 CFR 75.1101-9 - Back-up water system.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Back-up water system. 75.1101-9 Section 75.1101-9 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Fire Protection § 75.1101-9 Back-up water system...

Kepler Mission: End-to-End System Demonstration

NASA Technical Reports Server (NTRS)

Borucki, William; Koch, D.; Dunham, E.; Jenkins, J.; Witteborn, F.; Updike, T.; DeVincenzi, Donald L. (Technical Monitor)

2000-01-01

A test facility has been constructed to demonstrate the capability of differential ensemble photometry to detect transits of Earth-size planets orbiting solar-like stars. The main objective is to determine the effects of various noise sources on the capability of a CCD photometer to maintain a system relative precision of 1 x $10^(-5)$ for mv = 12 stars in the presence of system-induced noise sources. The facility includes a simulated star field, fast optics to simulate the telescope, a thinned back-illuminated CCD similar to those to be used on the spacecraft and computers to perform the onboard control, data processing and extraction. The test structure is thermally and mechanically isolated so that each source of noise can be introduced in a controlled fashion and evaluated for its contribution to the total noise budget. The effects of pointing errors or a changing thermal environment are imposed by piezo-electric devices. Transits are injected by heating small wires crossing apertures in the star plate. Signals as small as those from terrestrial-size transits of solar-like stars are introduced to demonstrate that such planets can be detected under realistic noise conditions. Examples of imposing several noise sources and the resulting detectabilities are presented. These show that a differential ensemble photometric approach CCD photometer can readily detect signals associated with Earth-size transits.

Electrophysiological assessment of piano players' back extensor muscles on a regular piano bench and chair with back rest.

PubMed

Honarmand, Kavan; Minaskanian, Rafael; Maboudi, Seyed Ebrahim; Oskouei, Ali E

2018-01-01

[Purpose] Sitting position is the dominant position for a professional pianist. There are many static and dynamic forces which affect musculoskeletal system during sitting. In prolonged sitting, these forces are harmful. The aim of this study was to compare pianists' back extensor muscles activity during playing piano while sitting on a regular piano bench and a chair with back rest. [Subjects and Methods] Ten professional piano players (mean age 25.4 ± 5.28, 60% male, 40% female) performed similar tasks for 5 hours in two sessions: one session sitting on a regular piano bench and the other sitting on a chair with back rest. In each session, muscular activity was assessed in 3 ways: 1) recording surface electromyography of the back-extensor muscles at the beginning and end of each session, 2) isometric back extension test, and 3) musculoskeletal discomfort questionnaire. [Results] There were significantly lesser muscular activity, more ability to perform isometric back extension and better personal comfort while sitting on a chair with back rest. [Conclusion] Decreased muscular activity and perhaps fatigue during prolonged piano playing on a chair with back rest may reduce acquired musculoskeletal disorders amongst professional pianists.

Electrophysiological assessment of piano players’ back extensor muscles on a regular piano bench and chair with back rest

PubMed Central

Honarmand, Kavan; Minaskanian, Rafael; Maboudi, Seyed Ebrahim; Oskouei, Ali E.

2018-01-01

[Purpose] Sitting position is the dominant position for a professional pianist. There are many static and dynamic forces which affect musculoskeletal system during sitting. In prolonged sitting, these forces are harmful. The aim of this study was to compare pianists’ back extensor muscles activity during playing piano while sitting on a regular piano bench and a chair with back rest. [Subjects and Methods] Ten professional piano players (mean age 25.4 ± 5.28, 60% male, 40% female) performed similar tasks for 5 hours in two sessions: one session sitting on a regular piano bench and the other sitting on a chair with back rest. In each session, muscular activity was assessed in 3 ways: 1) recording surface electromyography of the back-extensor muscles at the beginning and end of each session, 2) isometric back extension test, and 3) musculoskeletal discomfort questionnaire. [Results] There were significantly lesser muscular activity, more ability to perform isometric back extension and better personal comfort while sitting on a chair with back rest. [Conclusion] Decreased muscular activity and perhaps fatigue during prolonged piano playing on a chair with back rest may reduce acquired musculoskeletal disorders amongst professional pianists. PMID:29410569

Examination of the relationship between theory-driven policies and allowed lost-time back claims in workers' compensation: a system dynamics model.

PubMed

Wong, Jessica J; McGregor, Marion; Mior, Silvano A; Loisel, Patrick

2014-01-01

The purpose of this study was to develop a model that evaluates the impact of policy changes on the number of workers' compensation lost-time back claims in Ontario, Canada, over a 30-year timeframe. The model was used to test the hypothesis that a theory- and policy-driven model would be sufficient in reproducing historical claims data in a robust manner and that policy changes would have a major impact on modeled data. The model was developed using system dynamics methods in the Vensim simulation program. The theoretical effects of policies for compensation benefit levels and experience rating fees were modeled. The model was built and validated using historical claims data from 1980 to 2009. Sensitivity analysis was used to evaluate the modeled data at extreme end points of variable input and timeframes. The degree of predictive value of the modeled data was measured by the coefficient of determination, root mean square error, and Theil's inequality coefficients. Correlation between modeled data and actual data was found to be meaningful (R(2) = 0.934), and the modeled data were stable at extreme end points. Among the effects explored, policy changes were found to be relatively minor drivers of back claims data, accounting for a 13% improvement in error. Simulation results suggested that unemployment, number of no-lost-time claims, number of injuries per worker, and recovery rate from back injuries outside of claims management to be sensitive drivers of back claims data. A robust systems-based model was developed and tested for use in future policy research in Ontario's workers' compensation. The study findings suggest that certain areas within and outside the workers' compensation system need to be considered when evaluating and changing policies around back claims. © 2014. Published by National University of Health Sciences All rights reserved.

Real time monitoring of powder blend bulk density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process.

PubMed

Singh, Ravendra; Román-Ospino, Andrés D; Romañach, Rodolfo J; Ierapetritou, Marianthi; Ramachandran, Rohit

2015-11-10

The pharmaceutical industry is strictly regulated, where precise and accurate control of the end product quality is necessary to ensure the effectiveness of the drug products. For such control, the process and raw materials variability ideally need to be fed-forward in real time into an automatic control system so that a proactive action can be taken before it can affect the end product quality. Variations in raw material properties (e.g., particle size), feeder hopper level, amount of lubrication, milling and blending action, applied shear in different processing stages can affect the blend density significantly and thereby tablet weight, hardness and dissolution. Therefore, real time monitoring of powder bulk density variability and its incorporation into the automatic control system so that its effect can be mitigated proactively and efficiently is highly desired. However, real time monitoring of powder bulk density is still a challenging task because of different level of complexities. In this work, powder bulk density which has a significant effect on the critical quality attributes (CQA's) has been monitored in real time in a pilot-plant facility, using a NIR sensor. The sensitivity of the powder bulk density on critical process parameters (CPP's) and CQA's has been analyzed and thereby feed-forward controller has been designed. The measured signal can be used for feed-forward control so that the corrective actions on the density variations can be taken before they can influence the product quality. The coupled feed-forward/feed-back control system demonstrates improved control performance and improvements in the final product quality in the presence of process and raw material variations. Copyright © 2015 Elsevier B.V. All rights reserved.

End-to-End Information System design at the NASA Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

Hooke, A. J.

1978-01-01

Recognizing a pressing need of the 1980s to optimize the two-way flow of information between a ground-based user and a remote space-based sensor, an end-to-end approach to the design of information systems has been adopted at the Jet Propulsion Laboratory. The objectives of this effort are to ensure that all flight projects adequately cope with information flow problems at an early stage of system design, and that cost-effective, multi-mission capabilities are developed when capital investments are made in supporting elements. The paper reviews the End-to-End Information System (EEIS) activity at the Laboratory, and notes the ties to the NASA End-to-End Data System program.

Is back-electron transfer process in Betaine-30 coherent?

NASA Astrophysics Data System (ADS)

Rafiq, Shahnawaz; Scholes, Gregory D.

2017-09-01

The possible role of coherent vibrational motion in ultrafast photo-induced electron transfer remains unclear despite considerable experimental and theoretical advances. We revisited this problem by tracking the back-electron transfer (bET) process in Betaine-30 with broadband pump-probe spectroscopy. Dephasing time constant of certain high-frequency vibrations as a function of solvent shows a trend similar to the ET rates. In the purview of Bixon-Jortner model, high-frequency quantum vibrations bridge the reactant-product energy gap by providing activationless vibronic channels. Such interaction reduces the effective coupling significantly and thereby the coherence effects are eliminated due to energy gap fluctuations, making the back-electron transfer incoherent.

Low Back Imaging When Not Indicated: A Descriptive Cross-System Analysis.

PubMed

Gold, Rachel; Esterberg, Elizabeth; Hollombe, Celine; Arkind, Jill; Vakarcs, Patricia A; Tran, Huong; Burdick, Tim; Devoe, Jennifer E; Horberg, Michael A

2016-01-01

Guideline-discordant imaging to evaluate incident low back pain is common. We compared rates of guideline-discordant imaging in patients with low back pain in two care delivery systems with differing abilities to track care through an electronic health record (EHR), and in their patients' insurance status, to measure the association between these factors and rates of ordered low back imaging. We used data from two Kaiser Permanente (KP) Regions and from OCHIN, a community health center network. We extracted data on imaging performed after index visits for low back pain from June 1, 2011, to May 31, 2012, in these systems. Adjusted logistic regression measured associations between system-level factors and imaging rates. Imaging rates for incident low back pain using 2 national quality metrics: Clinical Quality Measure 0052, a measure for assessing Meaningful Use of EHRs, and the Healthcare Effectiveness Data and Information Set measure "Use of Imaging Studies for Low Back Pain." Among 19,503 KP patients and 2694 OCHIN patients with incident low back pain, ordered imaging was higher among men and whites but did not differ across health care systems. OCHIN's publicly insured patients had higher rates of imaging compared with those with private or no insurance. Rates of ordered imaging to evaluate incident low back pain among uninsured OCHIN patients were lower than in KP overall; among insured OCHIN patients, rates were higher than in KP overall. Research is needed to establish causality and develop interventions.

Open ended intelligence: the individuation of intelligent agents

NASA Astrophysics Data System (ADS)

Weinbaum Weaver, David; Veitas, Viktoras

2017-03-01

Artificial general intelligence is a field of research aiming to distil the principles of intelligence that operate independently of a specific problem domain and utilise these principles in order to synthesise systems capable of performing any intellectual task a human being is capable of and beyond. While "narrow" artificial intelligence which focuses on solving specific problems such as speech recognition, text comprehension, visual pattern recognition and robotic motion has shown impressive breakthroughs lately, understanding general intelligence remains elusive. We propose a paradigm shift from intelligence perceived as a competence of individual agents defined in relation to an a priori given problem domain or a goal, to intelligence perceived as a formative process of self-organisation. We call this process open-ended intelligence. Starting with a brief introduction of the current conceptual approach, we expose a number of serious limitations that are traced back to the ontological roots of the concept of intelligence. Open-ended intelligence is then developed as an abstraction of the process of human cognitive development, so its application can be extended to general agents and systems. We introduce and discuss three facets of the idea: the philosophical concept of individuation, sense-making and the individuation of general cognitive agents. We further show how open-ended intelligence can be framed in terms of a distributed, self-organising network of interacting elements and how such process is scalable. The framework highlights an important relation between coordination and intelligence and a new understanding of values.

Talking back: Development of the olivocochlear efferent system.

PubMed

Frank, Michelle M; Goodrich, Lisa V

2018-06-26

Developing sensory systems must coordinate the growth of neural circuitry spanning from receptors in the peripheral nervous system (PNS) to multilayered networks within the central nervous system (CNS). This breadth presents particular challenges, as nascent processes must navigate across the CNS-PNS boundary and coalesce into a tightly intermingled wiring pattern, thereby enabling reliable integration from the PNS to the CNS and back. In the auditory system, feedforward spiral ganglion neurons (SGNs) from the periphery collect sound information via tonotopically organized connections in the cochlea and transmit this information to the brainstem for processing via the VIII cranial nerve. In turn, feedback olivocochlear neurons (OCNs) housed in the auditory brainstem send projections into the periphery, also through the VIII nerve. OCNs are motor neuron-like efferent cells that influence auditory processing within the cochlea and protect against noise damage in adult animals. These aligned feedforward and feedback systems develop in parallel, with SGN central axons reaching the developing auditory brainstem around the same time that the OCN axons extend out toward the developing inner ear. Recent findings have begun to unravel the genetic and molecular mechanisms that guide OCN development, from their origins in a generic pool of motor neuron precursors to their specialized roles as modulators of cochlear activity. One recurrent theme is the importance of efferent-afferent interactions, as afferent SGNs guide OCNs to their final locations within the sensory epithelium, and efferent OCNs shape the activity of the developing auditory system. This article is categorized under: Nervous System Development > Vertebrates: Regional Development. © 2018 Wiley Periodicals, Inc.

Low Back Imaging When Not Indicated: A Descriptive Cross-System Analysis

PubMed Central

Gold, Rachel; Esterberg, Elizabeth; Hollombe, Celine; Arkind, Jill; Vakarcs, Patricia A; Tran, Huong; Burdick, Tim; DeVoe, Jennifer E; Horberg, Michael A

2016-01-01

Context: Guideline-discordant imaging to evaluate incident low back pain is common. Objective: We compared rates of guideline-discordant imaging in patients with low back pain in two care delivery systems with differing abilities to track care through an electronic health record (EHR), and in their patients’ insurance status, to measure the association between these factors and rates of ordered low back imaging. Design: We used data from two Kaiser Permanente (KP) Regions and from OCHIN, a community health center network. We extracted data on imaging performed after index visits for low back pain from June 1, 2011, to May 31, 2012, in these systems. Adjusted logistic regression measured associations between system-level factors and imaging rates. Main Outcome Measures: Imaging rates for incident low back pain using 2 national quality metrics: Clinical Quality Measure 0052, a measure for assessing Meaningful Use of EHRs, and the Healthcare Effectiveness Data and Information Set measure “Use of Imaging Studies for Low Back Pain.” Results: Among 19,503 KP patients and 2694 OCHIN patients with incident low back pain, ordered imaging was higher among men and whites but did not differ across health care systems. OCHIN’s publicly insured patients had higher rates of imaging compared with those with private or no insurance. Conclusion: Rates of ordered imaging to evaluate incident low back pain among uninsured OCHIN patients were lower than in KP overall; among insured OCHIN patients, rates were higher than in KP overall. Research is needed to establish causality and develop interventions. PMID:26934626

Assessing the economics of processing end-of-life vehicles through manual dismantling.

PubMed

Tian, Jin; Chen, Ming

2016-10-01

Most dismantling enterprises in a number of developing countries, such as China, usually adopt the "manual+mechanical" dismantling approach to process end-of-life vehicles. However, the automobile industry does not have a clear indicator to reasonably and effectively determine the manual dismantling degree for end-of-life vehicles. In this study, five different dismantling scenarios and an economic system for end-of-life vehicles were developed based on the actual situation of end-of-life vehicles. The fuzzy analytic hierarchy process was applied to set the weights of direct costs, indirect costs, and sales and to obtain an optimal manual dismantling scenario. Results showed that although the traditional method of "dismantling to the end" can guarantee the highest recycling rate, this method is not the best among all the scenarios. The profit gained in the optimal scenario is 100.6% higher than that in the traditional scenario. The optimal manual dismantling scenario showed that enterprises are required to select suitable parts to process through manual dismantling. Selecting suitable parts maximizes economic profit and improves dismantling speed. Copyright © 2016 Elsevier Ltd. All rights reserved.

40 CFR 63.494 - Back-end process provisions-residual organic HAP limitations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... technology or control or recovery devices. (1) For styrene butadiene rubber produced by the emulsion process... rubber produced by any process other than a solution or emulsion process, polybutadiene rubber produced...

Prevalence of low back pain and associated factors among farmers during the rice transplanting process

PubMed Central

Keawduangdee, Petcharat; Puntumetakul, Rungthip; Swangnetr, Manida; Laohasiriwong, Wongsa; Settheetham, Dariwan; Yamauchi, Junichiro; Boucaut, Rose

2015-01-01

[Purpose] The aim of this study was to investigate the prevalence of low back pain and associated factors in Thai rice farmers during the rice transplanting process. [Subjects and Methods] Three hundred and forty-four farmers, aged 20–59 years old, were asked to answer a questionnaire modified from the Standard Nordic Questionnaire (Thai version). The questionnaire sought demographic, back-related, and psychosocial data. [Results] The results showed that the prevalence of low back pain was 83.1%. Farmers younger than 45 years old who worked in the field fewer than six days were more likely to experience low back pain than those who worked for at least six days. Farmers with high stress levels were more likely to have low back pain. [Conclusion] In the rice transplanting process, the low back pain experienced by the farmers was associated with the weekly work duration and stress. PMID:26311961

Integration of Photo-Patternable Low-κ Material into Advanced Cu Back-End-Of-The-Line

NASA Astrophysics Data System (ADS)

Lin, Qinghuang; Nelson, Alshakim; Chen, Shyng-Tsong; Brock, Philip; Cohen, Stephan A.; Davis, Blake; Kaplan, Richard; Kwong, Ranee; Liniger, Eric; Neumayer, Debra; Patel, Jyotica; Shobha, Hosadurga; Sooriyakumaran, Ratnam; Purushothaman, Sampath; Miller, Robert; Spooner, Terry; Wisnieff, Robert

2010-05-01

We report herein the demonstration of a simple, low-cost Cu back-end-of-the-line (BEOL) dual-damascene integration using a novel photo-patternable low-κ dielectric material concept that dramatically reduces Cu BEOL integration complexity. This κ=2.7 photo-patternable low-κ material is based on the SiCOH-based material platform and has sub-200 nm resolution capability with 248 nm optical lithography. Cu/photo-patternable low-κ dual-damascene integration at 45 nm node BEOL fatwire levels has been demonstrated with very high electrical yields using the current manufacturing infrastructure. The photo-patternable low-κ concept is, therefore, a promising technology for highly efficient semiconductor Cu BEOL manufacturing.

FBI Fingerprint Image Capture System High-Speed-Front-End throughput modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rathke, P.M.

1993-09-01

The Federal Bureau of Investigation (FBI) has undertaken a major modernization effort called the Integrated Automated Fingerprint Identification System (IAFISS). This system will provide centralized identification services using automated fingerprint, subject descriptor, mugshot, and document processing. A high-speed Fingerprint Image Capture System (FICS) is under development as part of the IAFIS program. The FICS will capture digital and microfilm images of FBI fingerprint cards for input into a central database. One FICS design supports two front-end scanning subsystems, known as the High-Speed-Front-End (HSFE) and Low-Speed-Front-End, to supply image data to a common data processing subsystem. The production rate of themore » HSFE is critical to meeting the FBI`s fingerprint card processing schedule. A model of the HSFE has been developed to help identify the issues driving the production rate, assist in the development of component specifications, and guide the evolution of an operations plan. A description of the model development is given, the assumptions are presented, and some HSFE throughput analysis is performed.« less

An End-To-End Test of A Simulated Nuclear Electric Propulsion System

NASA Technical Reports Server (NTRS)

VanDyke, Melissa; Hrbud, Ivana; Goddfellow, Keith; Rodgers, Stephen L. (Technical Monitor)

2002-01-01

The Safe Affordable Fission Engine (SAFE) test series addresses Phase I Space Fission Systems issues in it particular non-nuclear testing and system integration issues leading to the testing and non-nuclear demonstration of a 400-kW fully integrated flight unit. The first part of the SAFE 30 test series demonstrated operation of the simulated nuclear core and heat pipe system. Experimental data acquired in a number of different test scenarios will validate existing computational models, demonstrated system flexibility (fast start-ups, multiple start-ups/shut downs), simulate predictable failure modes and operating environments. The objective of the second part is to demonstrate an integrated propulsion system consisting of a core, conversion system and a thruster where the system converts thermal heat into jet power. This end-to-end system demonstration sets a precedent for ground testing of nuclear electric propulsion systems. The paper describes the SAFE 30 end-to-end system demonstration and its subsystems.

Nursing process decision support system for urology ward.

PubMed

Hao, Angelica Te-Hui; Wu, Lee-Pin; Kumar, Ajit; Jian, Wen-Shan; Huang, Li-Fang; Kao, Ching-Chiu; Hsu, Chien-Yeh

2013-07-01

We developed a nursing process decision support system (NPDSS) based on three clinical pathways, including benign prostatic hypertrophy, inguinal hernia, and urinary tract stone. NPDSS included six major nursing diagnoses - acute pain, impaired urinary elimination, impaired skin integrity, anxiety, infection risk, and risk of falling. This paper aims to describe the design, development and validation process of the NPDSS. We deployed the Delphi method to reach consensus for decision support rules of NPDSS. A team of nine-member expert nurses from a medical center in Taiwan was involved in Delphi method. The Cronbach's α method was used for examining the reliability of the questionnaire used in the Delphi method. The Visual Basic 6.0 as front-end and Microsoft Access 2003 as back-end was used to develop the system. A team of six nursing experts was asked to evaluate the usability of the developed systems. A 5-point Likert scale questionnaire was used for the evaluation. The sensitivity and specificity of NPDSS were validated using 150 nursing chart. The study showed a consistency between the diagnoses of the developed system (NPDSS) and the nursing charts. The sensitivities of the nursing diagnoses including acute pain, impaired urinary elimination, risk of infection, and risk of falling were 96.9%, 98.1%, 94.9%, and 89.9% respectively; and the specificities were 88%, 49.5%, 62%, and 88% respectively. We did not calculate the sensitivity and specificity of impaired skin integrity and anxiety due to non-availability of enough sample size. NPDSS can help nurses in decision making of nursing diagnoses. Besides, it can help them to generate nursing diagnoses based on patient-specific data, individualized care plans, and implementation within their usual nursing workflow. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

The GOCE end-to-end system simulator

NASA Astrophysics Data System (ADS)

Catastini, G.; Cesare, S.; de Sanctis, S.; Detoma, E.; Dumontel, M.; Floberghagen, R.; Parisch, M.; Sechi, G.; Anselmi, A.

2003-04-01

The idea of an end-to-end simulator was conceived in the early stages of the GOCE programme, as an essential tool for assessing the satellite system performance, that cannot be fully tested on the ground. The simulator in its present form is under development at Alenia Spazio for ESA since the beginning of Phase B and is being used for checking the consistency of the spacecraft and of the payload specifications with the overall system requirements, supporting trade-off, sensitivity and worst-case analyses, and preparing and testing the on-ground and in-flight calibration concepts. The software simulates the GOCE flight along an orbit resulting from the application of Earth's gravity field, non-conservative environmental disturbances (atmospheric drag, coupling with Earth's magnetic field, etc.) and control forces/torques. The drag free control forces as well as the attitude control torques are generated by the current design of the dedicated algorithms. Realistic sensor models (star tracker, GPS receiver and gravity gradiometer) feed the control algorithms and the commanded forces are applied through realistic thruster models. The output of this stage of the simulator is a time series of Level-0 data, namely the gradiometer raw measurements and spacecraft ancillary data. The next stage of the simulator transforms Level-0 data into Level-1b (gravity gradient tensor) data, by implementing the following steps: - transformation of raw measurements of each pair of accelerometers into common and differential accelerations - calibration of the common and differential accelerations - application of the post-facto algorithm to rectify the phase of the accelerations and to estimate the GOCE angular velocity and attitude - computation of the Level-1b gravity gradient tensor from calibrated accelerations and estimated angular velocity in different reference frames (orbital, inertial, earth-fixed); computation of the spectral density of the error of the tensor diagonal

Image gathering, coding, and processing: End-to-end optimization for efficient and robust acquisition of visual information

NASA Technical Reports Server (NTRS)

Huck, Friedrich O.; Fales, Carl L.

1990-01-01

Researchers are concerned with the end-to-end performance of image gathering, coding, and processing. The applications range from high-resolution television to vision-based robotics, wherever the resolution, efficiency and robustness of visual information acquisition and processing are critical. For the presentation at this workshop, it is convenient to divide research activities into the following two overlapping areas: The first is the development of focal-plane processing techniques and technology to effectively combine image gathering with coding, with an emphasis on low-level vision processing akin to the retinal processing in human vision. The approach includes the familiar Laplacian pyramid, the new intensity-dependent spatial summation, and parallel sensing/processing networks. Three-dimensional image gathering is attained by combining laser ranging with sensor-array imaging. The second is the rigorous extension of information theory and optimal filtering to visual information acquisition and processing. The goal is to provide a comprehensive methodology for quantitatively assessing the end-to-end performance of image gathering, coding, and processing.

System of end-to-end symmetric database encryption

NASA Astrophysics Data System (ADS)

Galushka, V. V.; Aydinyan, A. R.; Tsvetkova, O. L.; Fathi, V. A.; Fathi, D. V.

2018-05-01

The article is devoted to the actual problem of protecting databases from information leakage, which is performed while bypassing access control mechanisms. To solve this problem, it is proposed to use end-to-end data encryption, implemented at the end nodes of an interaction of the information system components using one of the symmetric cryptographic algorithms. For this purpose, a key management method designed for use in a multi-user system based on the distributed key representation model, part of which is stored in the database, and the other part is obtained by converting the user's password, has been developed and described. In this case, the key is calculated immediately before the cryptographic transformations and is not stored in the memory after the completion of these transformations. Algorithms for registering and authorizing a user, as well as changing his password, have been described, and the methods for calculating parts of a key when performing these operations have been provided.

Versatile Stimulation Back-End With Programmable Exponential Current Pulse Shapes for a Retinal Visual Prosthesis.

PubMed

Maghami, Mohammad Hossein; Sodagar, Amir M; Sawan, Mohamad

2016-11-01

This paper reports on the design, implementation, and test of a stimulation back-end, for an implantable retinal prosthesis. In addition to traditional rectangular pulse shapes, the circuit features biphasic stimulation pulses with both rising and falling exponential shapes, whose time constants are digitally programmable. A class-B second generation current conveyor is used as a wide-swing, high-output-resistance stimulation current driver, delivering stimulation current pulses of up to ±96 μA to the target tissue. Duration of the generated current pulses is programmable within the range of 100 μs to 3 ms. Current-mode digital-to-analog converters (DACs) are used to program the amplitudes of the stimulation pulses. Fabricated using the IBM 130 nm process, the circuit consumes 1.5×1.5 mm 2 of silicon area. According to the measurements, the DACs exhibit DNL and INL of 0.23 LSB and 0.364 LSB, respectively. Experimental results indicate that the stimuli generator meets expected requirements when connected to electrode-tissue impedance of as high as 25 k Ω. Maximum power consumption of the proposed design is 3.4 mW when delivering biphasic rectangular pulses to the target load. A charge pump block is in charge of the upconversion of the standard 1.2-V supply voltage to ±3.3V.

Space-based multifunctional end effector systems functional requirements and proposed designs

NASA Technical Reports Server (NTRS)

Mishkin, A. H.; Jau, B. M.

1988-01-01

The end effector is an essential element of teleoperator and telerobot systems to be employed in space in the next decade. The report defines functional requirements for end effector systems to perform operations that are currently only feasible through Extra-Vehicular Activity (EVA). Specific tasks and functions that the end effectors must be capable of performing are delineated. Required capabilities for forces and torques, clearances, compliance, and sensing are described, using current EVA requirements as guidelines where feasible. The implications of these functional requirements on the elements of potential end effector systems are discussed. The systems issues that must be considered in the design of space-based manipulator systems are identified; including impacts on subsystems tightly coupled to the end effector, i.e., control station, information processing, manipulator arm, tool and equipment stowage. Possible end effector designs are divided into three categories: single degree-of-freedom end effectors, multiple degree of freedom end effectors, and anthropomorphic hands. Specific design alternatives are suggested and analyzed within the individual categories. Two evaluations are performed: the first considers how well the individual end effectors could substitute for EVA; the second compares how manipulator systems composed of the top performers from the first evaluation would improve the space shuttle Remote Manipulator System (RMS) capabilities. The analysis concludes that the anthropomorphic hand is best-suited for EVA tasks. A left- and right-handed anthropomorphic manipulator arm configuration is suggested as appropriate to be affixed to the RMS, but could also be used as part of the Smart Front End for the Orbital Maneuvering Vehicle (OMV). The technical feasibility of the anthropomorphic hand and its control are demonstrated. An evolutionary development approach is proposed and approximate scheduling provided for implementing the suggested

Minimally Invasive Microendoscopic Resection of the Transverse Process for Treatment of Low Back Pain with Bertolotti's Syndrome

PubMed Central

Sakai, Toshinori; Higashino, Kosaku; Goda, Yuichiro; Mineta, Kazuaki; Sairyo, Koichi

2014-01-01

Bertolotti's syndrome is characterized by anomalous enlargement of the transverse process of the most caudal lumbar segment, causing chronic and persistent low back pain or sciatica. We describe the case of a 45-year-old woman who presented with left sciatic pain and low back pain due to a recurrent lumbar disc herniation at L4-5 with Bertolotti's syndrome. Selective L5 nerve root block and local injection of lidocaine into the articulation between the transverse process and sacral ala temporarily relieved the left sciatic pain and low back pain, respectively. To confirm the effect of local injection on low back pain, we gave a second local injection, which once again relieved the low back pain. Microendoscopic resection of the pseudoarticulation region and discectomy successfully relieved all symptoms. This report illustrates the effectiveness of minimally invasive resection of the transverse process for the treatment of low back pain with Bertolotti's syndrome. PMID:25045566

Minimally Invasive Microendoscopic Resection of the Transverse Process for Treatment of Low Back Pain with Bertolotti's Syndrome.

PubMed

Takata, Yoichiro; Sakai, Toshinori; Higashino, Kosaku; Goda, Yuichiro; Mineta, Kazuaki; Sugiura, Kosuke; Sairyo, Koichi

2014-01-01

Bertolotti's syndrome is characterized by anomalous enlargement of the transverse process of the most caudal lumbar segment, causing chronic and persistent low back pain or sciatica. We describe the case of a 45-year-old woman who presented with left sciatic pain and low back pain due to a recurrent lumbar disc herniation at L4-5 with Bertolotti's syndrome. Selective L5 nerve root block and local injection of lidocaine into the articulation between the transverse process and sacral ala temporarily relieved the left sciatic pain and low back pain, respectively. To confirm the effect of local injection on low back pain, we gave a second local injection, which once again relieved the low back pain. Microendoscopic resection of the pseudoarticulation region and discectomy successfully relieved all symptoms. This report illustrates the effectiveness of minimally invasive resection of the transverse process for the treatment of low back pain with Bertolotti's syndrome.

Legal, institutional, and political issues in transportation of nuclear materials at the back end of the LWR nuclear fuel cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lippek, H.E.; Schuller, C.R.

1979-03-01

A study was conducted to identify major legal and institutional problems and issues in the transportation of spent fuel and associated processing wastes at the back end of the LWR nuclear fuel cycle. (Most of the discussion centers on the transportation of spent fuel, since this activity will involve virtually all of the legal and institutional problems likely to be encountered in moving waste materials, as well.) Actions or approaches that might be pursued to resolve the problems identified in the analysis are suggested. Two scenarios for the industrial-scale transportation of spent fuel and radioactive wastes, taken together, high-light mostmore » of the major problems and issues of a legal and institutional nature that are likely to arise: (1) utilizing the Allied General Nuclear Services (AGNS) facility at Barnwell, SC, as a temporary storage facility for spent fuel; and (2) utilizing AGNS for full-scale commercial reprocessing of spent LWR fuel.« less

Computation of Ground-State Properties in Molecular Systems: Back-Propagation with Auxiliary-Field Quantum Monte Carlo.

PubMed

Motta, Mario; Zhang, Shiwei

2017-11-14

We address the computation of ground-state properties of chemical systems and realistic materials within the auxiliary-field quantum Monte Carlo method. The phase constraint to control the Fermion phase problem requires the random walks in Slater determinant space to be open-ended with branching. This in turn makes it necessary to use back-propagation (BP) to compute averages and correlation functions of operators that do not commute with the Hamiltonian. Several BP schemes are investigated, and their optimization with respect to the phaseless constraint is considered. We propose a modified BP method for the computation of observables in electronic systems, discuss its numerical stability and computational complexity, and assess its performance by computing ground-state properties in several molecular systems, including small organic molecules.

Integrated seat frame and back support

DOEpatents

Martin, Leo

1999-01-01

An integrated seating device comprises a seat frame having a front end and a rear end. The seat frame has a double wall defining an exterior wall and an interior wall. The rear end of the seat frame has a slot cut therethrough both the exterior wall and the interior wall. The front end of the seat frame has a slot cut through just the interior wall thereof. A back support comprising a generally L shape has a horizontal member, and a generally vertical member which is substantially perpendicular to the horizontal member. The horizontal member is sized to be threaded through the rear slot and is fitted into the front slot. Welded slat means secures the back support to the seat frame to result in an integrated seating device.

An R-peak detection method that uses an SVD filter and a search back system.

PubMed

Jung, Woo-Hyuk; Lee, Sang-Goog

2012-12-01

In this paper, we present a method for detecting the R-peak of an ECG signal by using an singular value decomposition (SVD) filter and a search back system. The ECG signal was detected in two phases: the pre-processing phase and the decision phase. The pre-processing phase consisted of the stages for the SVD filter, Butterworth High Pass Filter (HPF), moving average (MA), and squaring, whereas the decision phase consisted of a single stage that detected the R-peak. In the pre-processing phase, the SVD filter removed noise while the Butterworth HPF eliminated baseline wander. The MA removed the remaining noise of the signal that had gone through the SVD filter to make the signal smooth, and squaring played a role in strengthening the signal. In the decision phase, the threshold was used to set the interval before detecting the R-peak. When the latest R-R interval (RRI), suggested by Hamilton et al., was greater than 150% of the previous RRI, the method of detecting the R-peak in such an interval was modified to be 150% or greater than the smallest interval of the two most latest RRIs. When the modified search back system was used, the error rate of the peak detection decreased to 0.29%, compared to 1.34% when the modified search back system was not used. Consequently, the sensitivity was 99.47%, the positive predictivity was 99.47%, and the detection error was 1.05%. Furthermore, the quality of the signal in data with a substantial amount of noise was improved, and thus, the R-peak was detected effectively. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Better End-Cap Processing for Oxidation-Resistant Polyimides

NASA Technical Reports Server (NTRS)

Meador, Mary Ann B.; Frimer, Aryeh A.

2004-01-01

A class of end-cap compounds that increase the thermo-oxidative stab ility of polyimides of the polymerization of monomeric reactants (PM R) type has been extended. In addition, an improved processing proto col for this class of end-cap compounds has been invented.

Experimental recovery of quantum correlations in absence of system-environment back-action.

PubMed

Xu, Jin-Shi; Sun, Kai; Li, Chuan-Feng; Xu, Xiao-Ye; Guo, Guang-Can; Andersson, Erika; Lo Franco, Rosario; Compagno, Giuseppe

2013-01-01

Revivals of quantum correlations in composite open quantum systems are a useful dynamical feature against detrimental effects of the environment. Their occurrence is attributed to flows of quantum information back and forth from systems to quantum environments. However, revivals also show up in models where the environment is classical, thus unable to store quantum correlations, and forbids system-environment back-action. This phenomenon opens basic issues about its interpretation involving the role of classical environments, memory effects, collective effects and system-environment correlations. Moreover, an experimental realization of back-action-free quantum revivals has applicative relevance as it leads to recover quantum resources without resorting to more demanding structured environments and correction procedures. Here we introduce a simple two-qubit model suitable to address these issues. We then report an all-optical experiment which simulates the model and permits us to recover and control, against decoherence, quantum correlations without back-action. We finally give an interpretation of the phenomenon by establishing the roles of the involved parties.

National supply-chain survey of drug manufacturer back orders.

PubMed

Wellman, G S

2001-07-01

The impact of manufacturer back orders on the supply chain for pharmaceuticals in the institutional setting was studied. A questionnaire was distributed during May and June 2000 to 600 institutional pharmacies affiliated with a major national drug and supply group purchasing organization. The instrument included questions on basic institutional demographics, perceptions about the frequency of manufacturer back orders for pharmaceuticals, the quality of communication with manufacturers and wholesalers about back orders, the two most significant back orders that had occurred in the 12 months preceding the survey, and the reasons for and impact of back orders. A total of 170 usable surveys were returned (net response rate, 28.3%). Reported manufacturer back orders included an array of drug classes, including blood products, antimicrobials, antiarrhythmics, benzodiazepine antagonists, thrombolytics, corticosteroids, and antihypertensives. Respondents perceived significant back orders as increasing in frequency. Communication by manufacturers and wholesalers about back orders was reported to be relatively poor. A raw-material shortage was the most common reason given by manufacturers for back orders (36.5%), followed by a regulatory issue (23.2%). In most cases (92%), medical staff members had to be contacted, indicating an interruption in the normal drug distribution process. In over a third of instances, respondents stated that the back order resulted in less optimal therapy. A survey found that manufacturer back orders for pharmaceuticals were increasing in frequency and that information flow within the supply chain was insufficient to meet the needs of end users.

Integration of Fiber-Optic Sensor Arrays into a Multi-Modal Tactile Sensor Processing System for Robotic End-Effectors

PubMed Central

Kampmann, Peter; Kirchner, Frank

2014-01-01

With the increasing complexity of robotic missions and the development towards long-term autonomous systems, the need for multi-modal sensing of the environment increases. Until now, the use of tactile sensor systems has been mostly based on sensing one modality of forces in the robotic end-effector. The use of a multi-modal tactile sensory system is motivated, which combines static and dynamic force sensor arrays together with an absolute force measurement system. This publication is focused on the development of a compact sensor interface for a fiber-optic sensor array, as optic measurement principles tend to have a bulky interface. Mechanical, electrical and software approaches are combined to realize an integrated structure that provides decentralized data pre-processing of the tactile measurements. Local behaviors are implemented using this setup to show the effectiveness of this approach. PMID:24743158

AIRSAR Automated Web-based Data Processing and Distribution System

NASA Technical Reports Server (NTRS)

Chu, Anhua; vanZyl, Jakob; Kim, Yunjin; Lou, Yunling; Imel, David; Tung, Wayne; Chapman, Bruce; Durden, Stephen

2005-01-01

In this paper, we present an integrated, end-to-end synthetic aperture radar (SAR) processing system that accepts data processing requests, submits processing jobs, performs quality analysis, delivers and archives processed data. This fully automated SAR processing system utilizes database and internet/intranet web technologies to allow external users to browse and submit data processing requests and receive processed data. It is a cost-effective way to manage a robust SAR processing and archival system. The integration of these functions has reduced operator errors and increased processor throughput dramatically.

An end-to-end communications architecture for condition-based maintenance applications

NASA Astrophysics Data System (ADS)

Kroculick, Joseph

2014-06-01

This paper explores challenges in implementing an end-to-end communications architecture for Condition-Based Maintenance Plus (CBM+) data transmission which aligns with the Army's Network Modernization Strategy. The Army's Network Modernization strategy is based on rolling out network capabilities which connect the smallest unit and Soldier level to enterprise systems. CBM+ is a continuous improvement initiative over the life cycle of a weapon system or equipment to improve the reliability and maintenance effectiveness of Department of Defense (DoD) systems. CBM+ depends on the collection, processing and transport of large volumes of data. An important capability that enables CBM+ is an end-to-end network architecture that enables data to be uploaded from the platform at the tactical level to enterprise data analysis tools. To connect end-to-end maintenance processes in the Army's supply chain, a CBM+ network capability can be developed from available network capabilities.

Chronic low back pain in patients with systemic lupus erythematosus: prevalence and predictors of back muscle strength and its correlation with disability.

PubMed

Cezarino, Raíssa Sudré; Cardoso, Jefferson Rosa; Rodrigues, Kedma Neves; Magalhães, Yasmin Santana; Souza, Talita Yokoy de; Mota, Lícia Maria Henrique da; Bonini-Rocha, Ana Clara; McVeigh, Joseph; Martins, Wagner Rodrigues

To determine the prevalence of Chronic Low Back Pain and predictors of Back Muscle Strength in patients with Systemic Lupus Erythematosus. Cross-sectional study. Ninety-six ambulatory patients with lupus were selected by non-probability sampling and interviewed and tested during medical consultation. The outcomes measurements were: Point prevalence of chronic low back pain, Oswestry Disability Index, Tampa Scale of Kinesiophobia, Fatigue Severity Scale and maximal voluntary isometric contractions of handgrip and of the back muscles. Correlation coefficient and multiple linear regression were used in statistical analysis. Of the 96 individuals interviewed, 25 had chronic low back pain, indicating a point prevalence of 26% (92% women). The correlation between the Oswestry Index and maximal voluntary isometric contraction of the back muscles was r=-0.4, 95% CI [-0.68; -0.01] and between the maximal voluntary isometric contraction of handgrip and of the back muscles was r=0.72, 95% CI [0.51; 0.88]. The regression model presented the highest value of R 2 being observed when maximal voluntary isometric contraction of the back muscles was tested with five independent variables (63%). In this model handgrip strength was the only predictive variable (β=0.61, p=0.001). The prevalence of chronic low back pain in individuals with systemic lupus erythematosus was 26%. The maximal voluntary isometric contraction of the back muscles was 63% predicted by five variables of interest, however, only the handgrip strength was a statistically significant predictive variable. The maximal voluntary isometric contraction of the back muscles presented a linear relation directly proportional to handgrip and inversely proportional to Oswestry Index i.e. stronger back muscles are associated with lower disability scores. Copyright © 2017. Published by Elsevier Editora Ltda.

Experimental recovery of quantum correlations in absence of system-environment back-action

PubMed Central

Xu, Jin-Shi; Sun, Kai; Li, Chuan-Feng; Xu, Xiao-Ye; Guo, Guang-Can; Andersson, Erika; Lo Franco, Rosario; Compagno, Giuseppe

2013-01-01

Revivals of quantum correlations in composite open quantum systems are a useful dynamical feature against detrimental effects of the environment. Their occurrence is attributed to flows of quantum information back and forth from systems to quantum environments. However, revivals also show up in models where the environment is classical, thus unable to store quantum correlations, and forbids system-environment back-action. This phenomenon opens basic issues about its interpretation involving the role of classical environments, memory effects, collective effects and system-environment correlations. Moreover, an experimental realization of back-action-free quantum revivals has applicative relevance as it leads to recover quantum resources without resorting to more demanding structured environments and correction procedures. Here we introduce a simple two-qubit model suitable to address these issues. We then report an all-optical experiment which simulates the model and permits us to recover and control, against decoherence, quantum correlations without back-action. We finally give an interpretation of the phenomenon by establishing the roles of the involved parties. PMID:24287554

Counter measures to effectively reduce end flare

NASA Astrophysics Data System (ADS)

Moneke, Matthias; Groche, Peter

2017-10-01

Roll forming is a manufacturing process, whose profitability is predicated on its high output. When roll formed profiles are cut to length, process related residual stresses are released and increased deformation at the profile ends at the cut-off occurs, also known as end flare. U-profiles typically show a flaring in at the lead end and a flaring out at the tail end. Due to this deformation, deviations from the dimensional accuracy can occur, which cause problems during further processing of the parts. Additional operations are necessary to compensate for the end flare, thereby increasing plant deployment time and production costs. Recent research focused on the cause of the residual stresses and it was shown, that a combination of residual longitudinal stresses and residual shear stresses are responsible for end flare. By exploiting this knowledge, it is possible to determine, depending on the flaring of the profile, in which part of the profile residual longitudinal or residual shear stresses are prevalent and which counter measures can specifically counteract the responsible residual stresses. For this purpose numerical and experimental investigations on a U-, Hat- and C-Profile were conducted. It could be shown that overbending and bending back of the profile is most effective in reducing end flare. Another developed method is lowering and elevating the profile to reduce residual longitudinal stresses.

Advanced End-to-end Simulation for On-board Processing (AESOP)

NASA Technical Reports Server (NTRS)

Mazer, Alan S.

1994-01-01

Developers of data compression algorithms typically use their own software together with commercial packages to implement, evaluate and demonstrate their work. While convenient for an individual developer, this approach makes it difficult to build on or use another's work without intimate knowledge of each component. When several people or groups work on different parts of the same problem, the larger view can be lost. What's needed is a simple piece of software to stand in the gap and link together the efforts of different people, enabling them to build on each other's work, and providing a base for engineers and scientists to evaluate the parts as a cohesive whole and make design decisions. AESOP (Advanced End-to-end Simulation for On-board Processing) attempts to meet this need by providing a graphical interface to a developer-selected set of algorithms, interfacing with compiled code and standalone programs, as well as procedures written in the IDL and PV-Wave command languages. As a proof of concept, AESOP is outfitted with several data compression algorithms integrating previous work on different processors (AT&T DSP32C, TI TMS320C30, SPARC). The user can specify at run-time the processor on which individual parts of the compression should run. Compressed data is then fed through simulated transmission and uncompression to evaluate the effects of compression parameters, noise and error correction algorithms. The following sections describe AESOP in detail. Section 2 describes fundamental goals for usability. Section 3 describes the implementation. Sections 4 through 5 describe how to add new functionality to the system and present the existing data compression algorithms. Sections 6 and 7 discuss portability and future work.

Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study.

PubMed

Ghosh, Preetam; Dullea, Robert; Fischer, James E; Turi, Tom G; Sarver, Ronald W; Zhang, Chaoyang; Basu, Kalyan; Das, Sajal K; Poland, Bradley W

2009-07-07

In this study, we formulate a computational reaction model following a chemical kinetic theory approach to predict the binding rate constant for the siRNA-RISC complex formation reaction. The model allowed us to study the potency difference between 2-nt 3' overhangs against blunt-ended siRNA molecules in an RNA interference (RNAi) system. The rate constant predicted by this model was fed into a stochastic simulation of the RNAi system (using the Gillespie stochastic simulator) to study the overall potency effect. We observed that the stochasticity in the transcription/translation machinery has no observable effects in the RNAi pathway. Sustained gene silencing using siRNAs can be achieved only if there is a way to replenish the dsRNA molecules in the cell. Initial findings show about 1.5 times more blunt-ended molecules will be required to keep the mRNA at the same reduced level compared to the 2-nt overhang siRNAs. However, the mRNA levels jump back to saturation after a longer time when blunt-ended siRNAs are used. We found that the siRNA-RISC complex formation reaction rate was 2 times slower when blunt-ended molecules were used pointing to the fact that the presence of the 2-nt overhangs has a greater effect on the reaction in which the bound RISC complex cleaves the mRNA.

Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study

PubMed Central

Ghosh, Preetam; Dullea, Robert; Fischer, James E; Turi, Tom G; Sarver, Ronald W; Zhang, Chaoyang; Basu, Kalyan; Das, Sajal K; Poland, Bradley W

2009-01-01

In this study, we formulate a computational reaction model following a chemical kinetic theory approach to predict the binding rate constant for the siRNA-RISC complex formation reaction. The model allowed us to study the potency difference between 2-nt 3' overhangs against blunt-ended siRNA molecules in an RNA interference (RNAi) system. The rate constant predicted by this model was fed into a stochastic simulation of the RNAi system (using the Gillespie stochastic simulator) to study the overall potency effect. We observed that the stochasticity in the transcription/translation machinery has no observable effects in the RNAi pathway. Sustained gene silencing using siRNAs can be achieved only if there is a way to replenish the dsRNA molecules in the cell. Initial findings show about 1.5 times more blunt-ended molecules will be required to keep the mRNA at the same reduced level compared to the 2-nt overhang siRNAs. However, the mRNA levels jump back to saturation after a longer time when blunt-ended siRNAs are used. We found that the siRNA-RISC complex formation reaction rate was 2 times slower when blunt-ended molecules were used pointing to the fact that the presence of the 2-nt overhangs has a greater effect on the reaction in which the bound RISC complex cleaves the mRNA. PMID:19594876

End-of-fabrication CMOS process monitor

NASA Technical Reports Server (NTRS)

Buehler, M. G.; Allen, R. A.; Blaes, B. R.; Hannaman, D. J.; Lieneweg, U.; Lin, Y.-S.; Sayah, H. R.

1990-01-01

A set of test 'modules' for verifying the quality of a complementary metal oxide semiconductor (CMOS) process at the end of the wafer fabrication is documented. By electrical testing of specific structures, over thirty parameters are collected characterizing interconnects, dielectrics, contacts, transistors, and inverters. Each test module contains a specification of its purpose, the layout of the test structure, the test procedures, the data reduction algorithms, and exemplary results obtained from 3-, 2-, or 1.6-micrometer CMOS/bulk processes. The document is intended to establish standard process qualification procedures for Application Specific Integrated Circuits (ASIC's).

Web-Accessible Scientific Workflow System for Performance Monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roelof Versteeg; Roelof Versteeg; Trevor Rowe

2006-03-01

We describe the design and implementation of a web accessible scientific workflow system for environmental monitoring. This workflow environment integrates distributed, automated data acquisition with server side data management and information visualization through flexible browser based data access tools. Component technologies include a rich browser-based client (using dynamic Javascript and HTML/CSS) for data selection, a back-end server which uses PHP for data processing, user management, and result delivery, and third party applications which are invoked by the back-end using webservices. This environment allows for reproducible, transparent result generation by a diverse user base. It has been implemented for several monitoringmore » systems with different degrees of complexity.« less

High-resolution physical and biogeochemical variability from a shallow back reef on Ofu, American Samoa: an end-member perspective

NASA Astrophysics Data System (ADS)

Koweek, David A.; Dunbar, Robert B.; Monismith, Stephen G.; Mucciarone, David A.; Woodson, C. Brock; Samuel, Lianna

2015-09-01

Shallow back reefs commonly experience greater thermal and biogeochemical variability owing to a combination of coral community metabolism, environmental forcing, flow regime, and water depth. We present results from a high-resolution (sub-hourly to sub-daily) hydrodynamic and biogeochemical study, along with a coupled long-term (several months) hydrodynamic study, conducted on the back reefs of Ofu, American Samoa. During the high-resolution study, mean temperature was 29.0 °C with maximum temperatures near 32 °C. Dissolved oxygen concentrations spanned 32-178 % saturation, and pHT spanned the range from 7.80 to 8.39 with diel ranges reaching 0.58 units. Empirical cumulative distribution functions reveal that pHT was between 8.0 and 8.2 during only 30 % of the observational period, with approximately even distribution of the remaining 70 % of the time between pHT values less than 8.0 and greater than 8.2. Thermal and biogeochemical variability in the back reefs is partially controlled by tidal modulation of wave-driven flow, which isolates the back reefs at low tide and brings offshore water into the back reefs at high tide. The ratio of net community calcification to net community production was 0.15 ± 0.01, indicating that metabolism on the back reef was dominated by primary production and respiration. Similar to other back reef systems, the back reefs of Ofu are carbon sinks during the daytime. Shallow back reefs like those in Ofu may provide insights for how coral communities respond to extreme temperatures and acidification and are deserving of continued attention.

Status report of the end-to-end ASKAP software system: towards early science operations

NASA Astrophysics Data System (ADS)

Guzman, Juan Carlos; Chapman, Jessica; Marquarding, Malte; Whiting, Matthew

2016-08-01

300 MHz bandwidth for Array Release 1; followed by the deployment of the real-time data processing components. In addition to the Central Processor, the first production release of the CSIRO ASKAP Science Data Archive (CASDA) has also been deployed in one of the Pawsey Supercomputing Centre facilities and it is integrated to the end-to-end ASKAP data flow system. This paper describes the current status of the "end-to-end" data flow software system from preparing observations to data acquisition, processing and archiving; and the challenges of integrating an HPC facility as a key part of the instrument. It also shares some lessons learned since the start of integration activities and the challenges ahead in preparation for the start of the Early Science program.

Spitzer Telemetry Processing System

NASA Technical Reports Server (NTRS)

Stanboli, Alice; Martinez, Elmain M.; McAuley, James M.

2013-01-01

The Spitzer Telemetry Processing System (SirtfTlmProc) was designed to address objectives of JPL's Multi-mission Image Processing Lab (MIPL) in processing spacecraft telemetry and distributing the resulting data to the science community. To minimize costs and maximize operability, the software design focused on automated error recovery, performance, and information management. The system processes telemetry from the Spitzer spacecraft and delivers Level 0 products to the Spitzer Science Center. SirtfTlmProc is a unique system with automated error notification and recovery, with a real-time continuous service that can go quiescent after periods of inactivity. The software can process 2 GB of telemetry and deliver Level 0 science products to the end user in four hours. It provides analysis tools so the operator can manage the system and troubleshoot problems. It automates telemetry processing in order to reduce staffing costs.

40 CFR 63.487 - Batch front-end process vents-reference control technology.

Code of Federal Regulations, 2010 CFR

2010-07-01

... § 63.487 Batch front-end process vents—reference control technology. (a) Batch front-end process vents... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Batch front-end process vents-reference control technology. 63.487 Section 63.487 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

Creating a multidisciplinary low back pain guideline: anatomy of a guideline adaptation process.

PubMed

Harstall, Christa; Taenzer, Paul; Angus, Donna K; Moga, Carmen; Schuller, Tara; Scott, N Ann

2011-08-01

A collaborative, multidisciplinary guideline adaptation process was developed to construct a single overarching, evidence-based clinical practice guideline (CPG) for all primary care practitioners responsible for the management of low back pain (LBP) to curb the use of ineffective treatments and improve patient outcomes. The adaptation strategy, which involved multiple committees and partnerships, leveraged existing knowledge transfer connections to recruit guideline development group (GDG) members and ensure that all stakeholders had a voice in the guideline development process. Videoconferencing was used to coordinate the large, geographically dispersed GDG. Information services and health technology assessment experts were used throughout the process to lighten the GDG's workload. The GDG reviewed seven seed guidelines and drafted an Alberta-specific guideline during 10 half-day meetings over a 12-month period. The use of ad hoc subcommittees to resolve uncertainties or disagreements regarding evidence interpretation expedited the process. Challenges were encountered in dealing with subjectivity, guideline appraisal tools, evidence source limitations and inconsistencies, and the lack of sophisticated evidence analysis inherent in guideline adaptation. Strategies for overcoming these difficulties are discussed. Guideline adaptation is useful when resources are limited and good-quality seed CPGs exist. The Ambassador Program successfully utilized existing stakeholder interest to create an overarching guideline that aligned guidance for LBP management across multiple primary care disciplines. Unforeseen challenges in guideline adaptation can be overcome with credible seed guidelines, a consistently applied and transparent methodology, and clear documentation of the subjective contextualization process. Multidisciplinary stakeholder input and an open, trusting relationship among all contributors will ensure that the end product is clinically meaningful. © 2010

Nematodes ultrastructure: complex systems and processes.

PubMed

Basyoni, Maha M A; Rizk, Enas M A

2016-12-01

Nematode worms are among the most ubiquitous organisms on earth. They include free-living forms as well as parasites of plants, insects, humans and other animals. Recently, there has been an explosion of interest in nematode biology, including the area of nematode ultrastructure. Nematodes are round with a body cavity. They have one way guts with a mouth at one end and an anus at the other. They have a pseudocoelom that is lined on one side with mesoderm and on the other side with endoderm. It appears that the cuticle is a very complex and evolutionarily plastic feature with important functions involving protection, body movement and maintaining shape. They only have longitudinal muscles so; they seem to thrash back and forth. While nematodes have digestive, reproductive, nervous and excretory systems, they do not have discrete circulatory or respiratory systems. Nematodes use chemosensory and mechanosensory neurons embedded in the cuticle to orient and respond to a wide range of environmental stimuli. Adults are made up of roughly 1000 somatic cells and hundreds of those cells are typically associated with the reproductive systems. Nematodes ultrastructure seeks to provide studies which enable their use as models for diverse biological processes including; human diseases, immunity, host-parasitic interactions and the expression of phylogenomics. The latter has, however, not been brought into a single inclusive entity. Consequently, in the current review we tried to provide a comprehensive approach to the current knowledge available for nematodes ultrastructures.

End-to-end system of license plate localization and recognition

NASA Astrophysics Data System (ADS)

Zhu, Siyu; Dianat, Sohail; Mestha, Lalit K.

2015-03-01

An end-to-end license plate recognition system is proposed. It is composed of preprocessing, detection, segmentation, and character recognition to find and recognize plates from camera-based still images. The system utilizes connected component (CC) properties to quickly extract the license plate region. A two-stage CC filtering is utilized to address both shape and spatial relationship information to produce high precision and to recall values for detection. Floating peak and valleys of projection profiles are used to cut the license plates into individual characters. A turning function-based method is proposed to quickly and accurately recognize each character. It is further accelerated using curvature histogram-based support vector machine. The INFTY dataset is used to train the recognition system, and MediaLab license plate dataset is used for testing. The proposed system achieved 89.45% F-measure for detection and 87.33% accuracy for overall recognition rate which is comparable to current state-of-the-art systems.

Net ecosystem calcification and net primary production in two Hawaii back-reef systems

NASA Astrophysics Data System (ADS)

Kiili, S.; Colbert, S.; Hart, K.

2016-02-01

Back-reef systems have complex carbon cycling, driven by dominant benthic communities that change with environmental conditions and display characteristic patterns of net primary production (NP) and net ecosystem calcification (G). The G/NP ratio provides a fundamental community-level assessment to compare systems spatially and to evaluate temporal changes in carbon cycling. Carbon dynamics were examined at leeward Hōnaunau and windward Waíōpae, Hawaíi Island. Both locations discharge brackish groundwater, including geothermal water at Waíōpae. The change in total CO2 (TCO2) and total alkalinity (TA) between morning and afternoon was measured to calculate the G/NP ratio along a salinity gradient. At both sites, aragonite saturation (ΩAr) was lower than open ocean conditions, and increased with salinity. Between the morning and afternoon, ΩAr increased by at least 1 as photosynthesis consumed CO2. At Waíōpae, water was corrosive to aragonite due to the input of acidic groundwater, but not at Honaunau, demonstrating the importance of local watershed characteristics on ΩAr. Across the salinity gradient, TA and TCO2 decreased between morning and afternoon. At Hōnaunau, G/NP increased from 0.11 to 0.31 with salinity, consistent with an offshore increase in coral cover. But at Waíōpae, G/NP decreased from 0.49 to 0.0 with salinity, despite an increase in coral cover with salinity. Low G may be caused by benthic processes, including coral bleaching or high rates of carbonate dissolution in interstitial waters between tide pools. Broader environmental conditions than just salinity, including pH of fresh groundwater inputs, shape the carbon cycling in the back-reef system. Examining the G/NP ratio of a back-reef system allows for a simple method to establish community level activity, and possibly indicate changes in a dynamic system.

Front-end electronics and DAQ for the EURITRACK tagged neutron inspection system

NASA Astrophysics Data System (ADS)

Lunardon, M.; Bottosso, C.; Fabris, D.; Moretto, S.; Nebbia, G.; Pesente, S.; Viesti, G.; Bigongiari, A.; Colonna, A.; Tintori, C.; Valkovic, V.; Sudac, D.; Peerani, P.; Sequeira, V.; Salvato, M.

2007-08-01

The EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) Front-End and Data Acquisition System is a compact set of VME boards interfaced with a standard PC. The system is part of a cargo container inspection portal based on the tagged neutrons technique. The front-end processes all detector signals and checks coincidences between any of the 64 pixels of the alpha particle detector and any gamma-ray signals in 22 NaI(Tl) scintillators. The system is capable of handling the data flow at neutron flux up to the portal limiting value of 108 neutrons/second. Some typical applications are presented.

4. EXTERIOR OF SOUTH END OF BUILDING 108 SHOWING STORM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. EXTERIOR OF SOUTH END OF BUILDING 108 SHOWING STORM PORCH ADDITION AND WINDOWS ALONG BACK (WEST SIDE) OF HOUSE. NOTE ORIGNAL SHORT CHIMNEY AT CREST OF ROOF. VIEW TO NORTH. - Rush Creek Hydroelectric System, Clubhouse Cottage, Rush Creek, June Lake, Mono County, CA

The complex spine: the multidimensional system of causal pathways for low-back disorders.

PubMed

Marras, William S

2012-12-01

The aim of this study was to examine the logic behind the knowledge of low-back problem causal pathways. Low-back pain and low-back disorders (LBDs) continue to represent the major musculoskeletal risk problem in the workplace,with the prevalence and costs of such disorders increasing over time. In recent years, there has been much criticism of the ability of ergonomics methods to control the risk of LBDs. Logical assessment of the systems logic associated with our understanding and prevention of LBDs. Current spine loading as well as spine tolerance research efforts are bringing the field to the point where there is a better systems understanding of the inextricable link between the musculoskeletal system and the cognitive system. Loading is influenced by both the physical environment factors as well as mental demands, whereas tolerances are defined by both physical tissue tolerance and biochemically based tissue sensitivities to pain. However, the logic used in many low-back risk assessment tools may be overly simplistic, given what is understood about causal pathways. Current tools typically assess only load or position in a very cursory manner. Efforts must work toward satisfying both the physical environment and the cognitive environment for the worker if one is to reliably lower the risk of low-back problems. This systems representation of LBD development may serve as a guide to identify gaps in our understanding of LBDs.

Preventing "Back-atcha": Improving Secondary School Instruction by Introducing Prospective Teachers to Historiography

ERIC Educational Resources Information Center

Blaszak, Barbara J.

2010-01-01

The author is always looking for material to use in her campaign to end the educational "back-atcha" cycle. It is a multi-generational process, wherein unsophisticated fact-centered high school instruction turns out students resilient against understanding historical discipline despite their college courses; these students then go on to…

Development of a Control System for the Teat-End Vacuum in Individual Quarter Milking Systems

PubMed Central

Ströbel, Ulrich; Rose-Meierhöfer, Sandra; Öz, Hülya; Brunsch, Reiner

2013-01-01

Progress in sensor technique and electronics has led to a decrease in the costs of electronic and sensor components. In modern dairy farms, having udders in good condition, a lower frequency of udder disease and an extended service life of dairy cows will help ensure competitiveness. The objective of this study was to develop a teat-end vacuum control system with individual quarter actor reaction. Based on a review of the literature, this system is assumed to protect the teat tissue. It reduces the mean teat-end vacuum in the maximum vacuum phase (b) to a level of 20 kPa at a flow rate of 0.25 L/min per quarter. At flow rates higher than 1.50 L/min per quarter, the teat-end vacuum can be controlled to a level of 30 kPa, because in this case it is desirable to have a higher vacuum for the transportation of the milk to the receiver. With this system it is possible for the first time to supply the teat end with low vacuum at low flow rates and with higher vacuum at increasing flow rates in a continuous process with a three second reaction-rate on individual quarter level. This system is completely automated. PMID:23765272

Neural network for processing both spatial and temporal data with time based back-propagation

NASA Technical Reports Server (NTRS)

Villarreal, James A. (Inventor); Shelton, Robert O. (Inventor)

1993-01-01

Neural networks are computing systems modeled after the paradigm of the biological brain. For years, researchers using various forms of neural networks have attempted to model the brain's information processing and decision-making capabilities. Neural network algorithms have impressively demonstrated the capability of modeling spatial information. On the other hand, the application of parallel distributed models to the processing of temporal data has been severely restricted. The invention introduces a novel technique which adds the dimension of time to the well known back-propagation neural network algorithm. In the space-time neural network disclosed herein, the synaptic weights between two artificial neurons (processing elements) are replaced with an adaptable-adjustable filter. Instead of a single synaptic weight, the invention provides a plurality of weights representing not only association, but also temporal dependencies. In this case, the synaptic weights are the coefficients to the adaptable digital filters. Novelty is believed to lie in the disclosure of a processing element and a network of the processing elements which are capable of processing temporal as well as spacial data.

Understanding and addressing racial/ethnic disproportionality in the front end of the child welfare system.

PubMed

Osterling, Kathy Lemon; D'Andrade, Amy; Austin, Michael J

2008-01-01

Racial/ethnic disproportionality in the child welfare system is a complicated social problem that is receiving increasing amounts of attention from researchers and practitioners. This review of the literature examines disproportionality in the front-end of the child welfare system and interventions that may address it. While none of the interventions had evidence suggesting that they reduced disproportionality in child welfare front-end processes, some of the interventions may improve child welfare case processes related to disproportionality and outcomes for families of color.

Orion MPCV GN and C End-to-End Phasing Tests

NASA Technical Reports Server (NTRS)

Neumann, Brian C.

2013-01-01

End-to-end integration tests are critical risk reduction efforts for any complex vehicle. Phasing tests are an end-to-end integrated test that validates system directional phasing (polarity) from sensor measurement through software algorithms to end effector response. Phasing tests are typically performed on a fully integrated and assembled flight vehicle where sensors are stimulated by moving the vehicle and the effectors are observed for proper polarity. Orion Multi-Purpose Crew Vehicle (MPCV) Pad Abort 1 (PA-1) Phasing Test was conducted from inertial measurement to Launch Abort System (LAS). Orion Exploration Flight Test 1 (EFT-1) has two end-to-end phasing tests planned. The first test from inertial measurement to Crew Module (CM) reaction control system thrusters uses navigation and flight control system software algorithms to process commands. The second test from inertial measurement to CM S-Band Phased Array Antenna (PAA) uses navigation and communication system software algorithms to process commands. Future Orion flights include Ascent Abort Flight Test 2 (AA-2) and Exploration Mission 1 (EM-1). These flights will include additional or updated sensors, software algorithms and effectors. This paper will explore the implementation of end-to-end phasing tests on a flight vehicle which has many constraints, trade-offs and compromises. Orion PA-1 Phasing Test was conducted at White Sands Missile Range (WSMR) from March 4-6, 2010. This test decreased the risk of mission failure by demonstrating proper flight control system polarity. Demonstration was achieved by stimulating the primary navigation sensor, processing sensor data to commands and viewing propulsion response. PA-1 primary navigation sensor was a Space Integrated Inertial Navigation System (INS) and Global Positioning System (GPS) (SIGI) which has onboard processing, INS (3 accelerometers and 3 rate gyros) and no GPS receiver. SIGI data was processed by GN&C software into thrust magnitude and

40 CFR 63.494 - Back-end process provisions-residual organic HAP and emission limitations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... produced by the emulsion process, polybutadiene rubber and styrene butadiene rubber produced by the... styrene butadiene rubber produced by the emulsion process: (i) A monthly weighted average of 0.40 kg... than a solution or emulsion process, polybutadiene rubber produced by any process other than a solution...

30 CFR 75.1101-21 - Back-up water system.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Back-up water system. 75.1101-21 Section 75.1101-21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY... water system. One fire hose outlet together with a length of hose capable of extending to the belt drive...

30 CFR 75.1101-21 - Back-up water system.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Back-up water system. 75.1101-21 Section 75.1101-21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY... water system. One fire hose outlet together with a length of hose capable of extending to the belt drive...

30 CFR 75.1101-21 - Back-up water system.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Back-up water system. 75.1101-21 Section 75.1101-21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY... water system. One fire hose outlet together with a length of hose capable of extending to the belt drive...

30 CFR 75.1101-21 - Back-up water system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Back-up water system. 75.1101-21 Section 75.1101-21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY... water system. One fire hose outlet together with a length of hose capable of extending to the belt drive...

30 CFR 75.1101-21 - Back-up water system.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Back-up water system. 75.1101-21 Section 75.1101-21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY... water system. One fire hose outlet together with a length of hose capable of extending to the belt drive...

Flexible End2End Workflow Automation of Hit-Discovery Research.

PubMed

Holzmüller-Laue, Silke; Göde, Bernd; Thurow, Kerstin

2014-08-01

The article considers a new approach of more complex laboratory automation at the workflow layer. The authors purpose the automation of end2end workflows. The combination of all relevant subprocesses-whether automated or manually performed, independently, and in which organizational unit-results in end2end processes that include all result dependencies. The end2end approach focuses on not only the classical experiments in synthesis or screening, but also on auxiliary processes such as the production and storage of chemicals, cell culturing, and maintenance as well as preparatory activities and analyses of experiments. Furthermore, the connection of control flow and data flow in the same process model leads to reducing of effort of the data transfer between the involved systems, including the necessary data transformations. This end2end laboratory automation can be realized effectively with the modern methods of business process management (BPM). This approach is based on a new standardization of the process-modeling notation Business Process Model and Notation 2.0. In drug discovery, several scientific disciplines act together with manifold modern methods, technologies, and a wide range of automated instruments for the discovery and design of target-based drugs. The article discusses the novel BPM-based automation concept with an implemented example of a high-throughput screening of previously synthesized compound libraries. © 2014 Society for Laboratory Automation and Screening.

Front-End and Back-End Database Design and Development: Scholar's Academy Case Study

ERIC Educational Resources Information Center

Parks, Rachida F.; Hall, Chelsea A.

2016-01-01

This case study consists of a real database project for a charter school--Scholar's Academy--and provides background information on the school and its cafeteria processing system. Also included are functional requirements and some illustrative data. Students are tasked with the design and development of a database for the purpose of improving the…

An In-Process Surface Roughness Recognition System in End Milling Operations

ERIC Educational Resources Information Center

Yang, Lieh-Dai; Chen, Joseph C.

2004-01-01

To develop an in-process quality control system, a sensor technique and a decision-making algorithm need to be applied during machining operations. Several sensor techniques have been used in the in-process prediction of quality characteristics in machining operations. For example, an accelerometer sensor can be used to monitor the vibration of…

A new fabrication technique for back-to-back varactor diodes

NASA Technical Reports Server (NTRS)

Smith, R. Peter; Choudhury, Debabani; Martin, Suzanne; Frerking, Margaret A.; Liu, John K.; Grunthaner, Frank A.

1992-01-01

A new varactor diode process has been developed in which much of the processing is done from the back of an extremely thin semiconductor wafer laminated to a low-dielectric substrate. Back-to-back BNN diodes were fabricated with this technique; excellent DC and low-frequency capacitance measurements were obtained. Advantages of the new technique relative to other techniques include greatly reduced frontside wafer damage from exposure to process chemicals, improved capability to integrate devices (e.g. for antenna patterns, transmission lines, or wafer-scale grids), and higher line yield. BNN diodes fabricated with this technique exhibit approximately the expected capacitance-voltage characteristics while showing leakage currents under 10 mA at voltages three times that needed to deplete the varactor. This leakage is many orders of magnitude better than comparable Schottky diodes.

Standardization of End-to-End Performance of Digital Video Teleconferencing/Video Telephony Systems

DTIC Science & Technology

1991-12-01

SYSTEM 3-1 end-to-end video transmission system including both firmly specified and peripheral flexible functions. The format converter changes either...which manifests itself in both subjective evaluations and objective tests. The relative importance of performance parameters is likely to change with...conventional analog performance parameters to be largely independent of bit rate, and only slightly changed between different codec models. The

40 CFR 63.491 - Batch front-end process vents-recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.491 Batch front-end process vents—recordkeeping requirements. (a) Group determination records for...) through (a)(6) of this section for each batch front-end process vent subject to the group determination...

40 CFR 63.491 - Batch front-end process vents-recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.491 Batch front-end process vents—recordkeeping requirements. (a) Group determination records for...) through (a)(6) of this section for each batch front-end process vent subject to the group determination...

40 CFR 63.491 - Batch front-end process vents-recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.491 Batch front-end process vents—recordkeeping requirements. (a) Group determination records for...) through (a)(6) of this section for each batch front-end process vent subject to the group determination...

40 CFR 63.491 - Batch front-end process vents-recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.491 Batch front-end process vents—recordkeeping requirements. (a) Group determination records for...) through (a)(6) of this section for each batch front-end process vent subject to the group determination...

Process optimization for reverse micellar extraction of stem bromelain with a focus on back extraction.

PubMed

Dhaneshwar, Amrut D; Chaurasiya, Ram Saran; Hebbar, H Umesh

2014-01-01

In the current study, reverse micellar extraction (RME) for the purification of stem bromelain was successfully achieved using the sodium bis(2-ethylhexyl) sulfosuccinate (AOT)/isooctane system. A maximum forward extraction efficiency of 58.0% was obtained at 100 mM AOT concentration, aqueous phase pH of 8.0 and 0.2 M NaCl. Back extraction studies on altering stripping phase pH and KCl concentration, addition of counter-ion and iso-propyl alcohol (IPA) and mechanical agitation with glass beads indicated that IPA addition and agitation with glass beads have significant effects on extraction efficiency. The protein extraction was higher (51.9%) in case of the IPA (10% v/v) added system during back extraction as compared to a cetyltrimethylammonium bromide (100 mM) added system (9.42%). The central composite design technique was used to optimize the back extraction conditions further. Concentration of IPA, amount of glass beads, mixing time, and agitation speed (in rpm) were the variables selected. IPA concentration of 8.5% (v/v), glass bead concentration of 0.6 (w/v), and mixing time of 45 min at 400 rpm resulted in higher back extraction efficiency of 45.6% and activity recovery of 88.8% with purification of 3.04-fold. The study indicated that mechanical agitation using glass beads could be used for destabilizing the reverse micelles and release of bromelain back into the fresh aqueous phase. © 2014 American Institute of Chemical Engineers.

[Roof folding and rotary pushing for the treatment of back to back fractures of distal radius and ulna in children].

PubMed

Xu, Ping; Dong, Xiao-jun; Lu, Zhou-tong; Wang, Gongjun; Zhang, Han-qing; Chen, Xuan-ning; Li, Dong

2015-09-01

To evaluate the technique and the clinical effect of folding roof and rotary pushing in treatment of children with distal radius and ulna fracture of "back to back". From January 2012 to February 2014,38 children with distal radius and ulna fracture of "back to back" were treated by using the technique of folding roof and rotary pushing to reset and splint fixation including 23 males and 15 females with an average age of 9.5 years old ranging from 6 to 14 years old. Injury time was from 45 min to 3 days (averaged 1.3 days). All cases was unilateral closed fracture without symptoms of nerve injury occurred. The wrist joint anteroposterior and lateral radiographs showed double fracture of radius and ulna, and the broken end of radius was typical "back to back" displacement. The quality of reduction was assessed according to Dienst recommendation on the combination of Aro measurement, and the therapeutic effect was evaluated using standard of Anderson function. All patients were followed up from 3 to 13 months with an average of 6 months. There were no iatrogenic nerve injury. Thirty cases were treated successfully for the first time, 8 cases were again reset successfully; 28 cases were anatomical reduction, 7 cases were near anatomic reduction, 3 cases were functional reduction. At the second day 7 cases with hand and finger swelling appeared in multiple reset patients. Quality results of reduction were excellent in 33 cases, good in 5 cases. According to the standard of Anderson function evaluation, 35 cases were excellent, 3 cases were good. All fractures were healed with of deformity of wrist. Using the technique of folding roof and rotary pushing in treatment of children with distal radius and ulna fracture of "back to back" is very successful, the patient's limb function recovered well, the whole operation process is simple.

Optimization of Tape Winding Process Parameters to Enhance the Performance of Solid Rocket Nozzle Throat Back Up Liners using Taguchi's Robust Design Methodology

NASA Astrophysics Data System (ADS)

Nath, Nayani Kishore

2017-08-01

The throat back up liners is used to protect the nozzle structural members from the severe thermal environment in solid rocket nozzles. The throat back up liners is made with E-glass phenolic prepregs by tape winding process. The objective of this work is to demonstrate the optimization of process parameters of tape winding process to achieve better insulative resistance using Taguchi's robust design methodology. In this method four control factors machine speed, roller pressure, tape tension, tape temperature that were investigated for the tape winding process. The presented work was to study the cogency and acceptability of Taguchi's methodology in manufacturing of throat back up liners. The quality characteristic identified was Back wall temperature. Experiments carried out using L 9 ' (34) orthogonal array with three levels of four different control factors. The test results were analyzed using smaller the better criteria for Signal to Noise ratio in order to optimize the process. The experimental results were analyzed conformed and successfully used to achieve the minimum back wall temperature of the throat back up liners. The enhancement in performance of the throat back up liners was observed by carrying out the oxy-acetylene tests. The influence of back wall temperature on the performance of throat back up liners was verified by ground firing test.

End-to-End Modeling with the Heimdall Code to Scope High-Power Microwave Systems

DTIC Science & Technology

2007-06-01

END-TO-END MODELING WITH THE HEIMDALL CODE TO SCOPE HIGH - POWER MICROWAVE SYSTEMS ∗ John A. Swegleξ Savannah River National Laboratory, 743A...describe the expert-system code HEIMDALL, which is used to model full high - power microwave systems using over 60 systems-engineering models, developed in...of our calculations of the mass of a Supersystem producing 500-MW, 15-ns output pulses in the X band for bursts of 1 s , interspersed with 10- s

Effect of Back Contact and Rapid Thermal Processing Conditions on Flexible CdTe Device Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahabaduge, Hasitha; Meysing, D. M.; Rance, Will L.

Flexible CdTe solar cells on ultra-thin glass substrates can enable new applications that require high specific power, unique form-factors, and low manufacturing costs. To be successful, these cells must be cost competitive, have high efficiency, and have high reliability. Here we present back contact processing conditions that enabled us to achieve over 16% efficiency on flexible Corning (R) Willow (R) Glass substrates. We used co-evaporated ZnTe:Cu and Au as our back contact and used rapid thermal processing (RTP) to activate the back contact. Both the ZnTe to Cu ratio and the RTP activation temperature provide independent control over the devicemore » performance. We have investigated the influence of various RTP conditions to Cu activation and distribution. Current density-voltage, capacitance-voltage measurements along with device simulations were used to examine the device performance in terms of ZnTe to Cu ratio and rapid thermal activation temperature.« less

Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro

PubMed Central

Jablonski, Joseph; Clementz, Mark; Ryan, Kevin; Valente, Susana T.

2014-01-01

The 3’ end of mammalian mRNAs is not formed by abrupt termination of transcription by RNA polymerase II (RNPII). Instead, RNPII synthesizes precursor mRNA beyond the end of mature RNAs, and an active process of endonuclease activity is required at a specific site. Cleavage of the precursor RNA normally occurs 10-30 nt downstream from the consensus polyA site (AAUAAA) after the CA dinucleotides. Proteins from the cleavage complex, a multifactorial protein complex of approximately 800 kDa, accomplish this specific nuclease activity. Specific RNA sequences upstream and downstream of the polyA site control the recruitment of the cleavage complex. Immediately after cleavage, pre-mRNAs are polyadenylated by the polyA polymerase (PAP) to produce mature stable RNA messages. Processing of the 3’ end of an RNA transcript may be studied using cellular nuclear extracts with specific radiolabeled RNA substrates. In sum, a long 32P-labeled uncleaved precursor RNA is incubated with nuclear extracts in vitro, and cleavage is assessed by gel electrophoresis and autoradiography. When proper cleavage occurs, a shorter 5’ cleaved product is detected and quantified. Here, we describe the cleavage assay in detail using, as an example, the 3’ end processing of HIV-1 mRNAs. PMID:24835792

PICASSO: an end-to-end image simulation tool for space and airborne imaging systems

NASA Astrophysics Data System (ADS)

Cota, Steve A.; Bell, Jabin T.; Boucher, Richard H.; Dutton, Tracy E.; Florio, Chris J.; Franz, Geoffrey A.; Grycewicz, Thomas J.; Kalman, Linda S.; Keller, Robert A.; Lomheim, Terrence S.; Paulson, Diane B.; Willkinson, Timothy S.

2008-08-01

The design of any modern imaging system is the end result of many trade studies, each seeking to optimize image quality within real world constraints such as cost, schedule and overall risk. Image chain analysis - the prediction of image quality from fundamental design parameters - is an important part of this design process. At The Aerospace Corporation we have been using a variety of image chain analysis tools for many years, the Parameterized Image Chain Analysis & Simulation SOftware (PICASSO) among them. In this paper we describe our PICASSO tool, showing how, starting with a high quality input image and hypothetical design descriptions representative of the current state of the art in commercial imaging satellites, PICASSO can generate standard metrics of image quality in support of the decision processes of designers and program managers alike.

PICASSO: an end-to-end image simulation tool for space and airborne imaging systems

NASA Astrophysics Data System (ADS)

Cota, Stephen A.; Bell, Jabin T.; Boucher, Richard H.; Dutton, Tracy E.; Florio, Christopher J.; Franz, Geoffrey A.; Grycewicz, Thomas J.; Kalman, Linda S.; Keller, Robert A.; Lomheim, Terrence S.; Paulson, Diane B.; Wilkinson, Timothy S.

2010-06-01

The design of any modern imaging system is the end result of many trade studies, each seeking to optimize image quality within real world constraints such as cost, schedule and overall risk. Image chain analysis - the prediction of image quality from fundamental design parameters - is an important part of this design process. At The Aerospace Corporation we have been using a variety of image chain analysis tools for many years, the Parameterized Image Chain Analysis & Simulation SOftware (PICASSO) among them. In this paper we describe our PICASSO tool, showing how, starting with a high quality input image and hypothetical design descriptions representative of the current state of the art in commercial imaging satellites, PICASSO can generate standard metrics of image quality in support of the decision processes of designers and program managers alike.

Integrating end-to-end threads of control into object-oriented analysis and design

NASA Technical Reports Server (NTRS)

Mccandlish, Janet E.; Macdonald, James R.; Graves, Sara J.

1993-01-01

Current object-oriented analysis and design methodologies fall short in their use of mechanisms for identifying threads of control for the system being developed. The scenarios which typically describe a system are more global than looking at the individual objects and representing their behavior. Unlike conventional methodologies that use data flow and process-dependency diagrams, object-oriented methodologies do not provide a model for representing these global threads end-to-end. Tracing through threads of control is key to ensuring that a system is complete and timing constraints are addressed. The existence of multiple threads of control in a system necessitates a partitioning of the system into processes. This paper describes the application and representation of end-to-end threads of control to the object-oriented analysis and design process using object-oriented constructs. The issue of representation is viewed as a grouping problem, that is, how to group classes/objects at a higher level of abstraction so that the system may be viewed as a whole with both classes/objects and their associated dynamic behavior. Existing object-oriented development methodology techniques are extended by adding design-level constructs termed logical composite classes and process composite classes. Logical composite classes are design-level classes which group classes/objects both logically and by thread of control information. Process composite classes further refine the logical composite class groupings by using process partitioning criteria to produce optimum concurrent execution results. The goal of these design-level constructs is to ultimately provide the basis for a mechanism that can support the creation of process composite classes in an automated way. Using an automated mechanism makes it easier to partition a system into concurrently executing elements that can be run in parallel on multiple processors.

A new system for measuring three-dimensional back shape in scoliosis

PubMed Central

Pynsent, Paul; Fairbank, Jeremy; Disney, Simon

2008-01-01

The aim of this work was to develop a low-cost automated system to measure the three-dimensional shape of the back in patients with scoliosis. The resulting system uses structured light to illuminate a patient’s back from an angle while a digital photograph is taken. The height of the surface is calculated using Fourier transform profilometry with an accuracy of ±1 mm. The surface is related to body axes using bony landmarks on the back that have been palpated and marked with small coloured stickers prior to photographing. Clinical parameters are calculated automatically and presented to the user on a monitor and as a printed report. All data are stored in a database. The database can be interrogated and successive measurements plotted for monitoring the deformity changes. The system developed uses inexpensive hardware and open source software. Accurate surface topography can help the clinician to measure spinal deformity at baseline and monitor changes over time. It can help the patients and their families to assess deformity. Above all it reduces the dependence on serial radiography and reduces radiation exposure when monitoring spinal deformity. PMID:18247064

Seeing the System through the End Users' Eyes: Shadow Expert Technique for Evaluating the Consistency of a Learning Management System

NASA Astrophysics Data System (ADS)

Holzinger, Andreas; Stickel, Christian; Fassold, Markus; Ebner, Martin

Interface consistency is an important basic concept in web design and has an effect on performance and satisfaction of end users. Consistency also has significant effects on the learning performance of both expert and novice end users. Consequently, the evaluation of consistency within a e-learning system and the ensuing eradication of irritating discrepancies in the user interface redesign is a big issue. In this paper, we report of our experiences with the Shadow Expert Technique (SET) during the evaluation of the consistency of the user interface of a large university learning management system. The main objective of this new usability evaluation method is to understand the interaction processes of end users with a specific system interface. Two teams of usability experts worked independently from each other in order to maximize the objectivity of the results. The outcome of this SET method is a list of recommended changes to improve the user interaction processes, hence to facilitate high consistency.

Information Processing in Cognition Process and New Artificial Intelligent Systems

NASA Astrophysics Data System (ADS)

Zheng, Nanning; Xue, Jianru

In this chapter, we discuss, in depth, visual information processing and a new artificial intelligent (AI) system that is based upon cognitive mechanisms. The relationship between a general model of intelligent systems and cognitive mechanisms is described, and in particular we explore visual information processing with selective attention. We also discuss a methodology for studying the new AI system and propose some important basic research issues that have emerged in the intersecting fields of cognitive science and information science. To this end, a new scheme for associative memory and a new architecture for an AI system with attractors of chaos are addressed.

The Different Role of Working Memory in Open-Ended versus Closed-Ended Creative Problem Solving: A Dual-Process Theory Account

ERIC Educational Resources Information Center

Lin, Wei-Lun; Lien, Yunn-Wen

2013-01-01

This study examined how working memory plays different roles in open-ended versus closed-ended creative problem-solving processes, as represented by divergent thinking tests and insight problem-solving tasks. With respect to the analysis of different task demands and the framework of dual-process theories, the hypothesis was that the idea…

40 CFR 63.487 - Batch front-end process vents-reference control technology.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-reference control technology. 63.487 Section 63.487 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.487 Batch front-end process vents—reference control technology. (a) Batch front-end process...

40 CFR 63.487 - Batch front-end process vents-reference control technology.

Code of Federal Regulations, 2011 CFR

2011-07-01

... control technology. 63.487 Section 63.487 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.487 Batch front-end process vents—reference control technology. (a) Batch front-end process vents...

40 CFR 63.487 - Batch front-end process vents-reference control technology.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-reference control technology. 63.487 Section 63.487 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.487 Batch front-end process vents—reference control technology. (a) Batch front-end process...

40 CFR 63.487 - Batch front-end process vents-reference control technology.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-reference control technology. 63.487 Section 63.487 Protection of Environment ENVIRONMENTAL PROTECTION... SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutant Emissions: Group I Polymers and Resins § 63.487 Batch front-end process vents—reference control technology. (a) Batch front-end process...

End-Directedness and Context in Nonliving Dissipative Systems

NASA Astrophysics Data System (ADS)

Dixon, James A.; Kay, Bruce A.; Davis, Tehran J.; Kondepudi, Dilip

Biological organisms are distinguished from non-living systems, in part, by their ability to choose and strive towards particular ends. This end-directed behavior is seen across all five biological kingdoms, from single-celled organisms to the most advanced primates. The ubiquitous nature of end-directedness, across such a wide variety of biological entities, suggests that a deeper principle may be at work. We propose that end-directedness, rather than being a special ability of living systems, is actually a fundamental property of a larger class of physical systems, called dissipative structures, which are formed and maintained by the flow of energy and matter. Our work shows that dissipative structures "behave so as to persist", seeking states that increase their rate of entropy production, and thus facilitate their own persistence. In addition, we suggest that biological entities create their exquisite sensitivity to context by interweaving this fundamental end-directedness with the contextual and physical constraints of their environments. The result is a repertoire of complex behavior. We provide an example of such complex behavior emerging from contextual and physical constraints coupled with end-directedness.

Targeted treatment in primary care for low back pain: the treatment system and clinical training programmes used in the IMPaCT Back study (ISRCTN 55174281)

PubMed Central

Sowden, Gail; Hill, Jonathan C; Konstantinou, Kika; Khanna, Meenee; Main, Chris J; Salmon, Paula; Somerville, Simon; Wathall, Simon; Foster, Nadine E

2012-01-01

Background. The IMPaCT Back study (IMplementation to improve Patient Care through Targeted treatment for Back pain) is a quality improvement study which aims to investigate the effects of introducing and supporting a subgrouping for targeted treatment system for patients with low back pain (LBP) in primary care. This paper details the subgrouping for targeted treatment system and the clinical training and mentoring programmes aimed at equipping clinicians to deliver it. The subgrouping and targeted treatment system. This system differs from ‘one-size fits all’ usual practice as it suggests that first contact health care practitioners should systematically allocate LBP patients to one of the three subgroups according to key modifiable prognostic indicators for chronicity. Patients in each subgroup (those at low, medium or high risk of chronicity) are then managed according to a targeted treatment system of increasing complexity. The subgrouping tools. Subgrouping tools help guide clinical decision-making about treatment and onward referral. Two subgrouping tools have been used in the IMPaCT Back study, a 9-item version used by participating physiotherapists and a 6-item version used by GPs. The targeted treatments. The targeted treatments include a minimal intervention delivered by GPs (for those patients at low risk of poor outcome) or referral to primary care physiotherapists who can apply physiotherapy approaches to addressing pain and disability (for those at medium risk) and additional cognitive-behavioural approaches to help address psychological and social obstacles to recovery (for those at high risk). The training packages. Building on previous interventions for other pilot studies and randomized trials, we have developed and delivered clinical training and support programmes for GPs and physiotherapists. Discussion. This paper describes in detail the IMPaCT Back study’s subgrouping for targeted treatment system and the training and mentoring packages

An evidence-based diagnostic classification system for low back pain

PubMed Central

Vining, Robert; Potocki, Eric; Seidman, Michael; Morgenthal, A. Paige

2013-01-01

Introduction: While clinicians generally accept that musculoskeletal low back pain (LBP) can arise from specific tissues, it remains difficult to confirm specific sources. Methods: Based on evidence supported by diagnostic utility studies, doctors of chiropractic functioning as members of a research clinic created a diagnostic classification system, corresponding exam and checklist based on strength of evidence, and in-office efficiency. Results: The diagnostic classification system contains one screening category, two pain categories: Nociceptive, Neuropathic, one functional evaluation category, and one category for unknown or poorly defined diagnoses. Nociceptive and neuropathic pain categories are each divided into 4 subcategories. Conclusion: This article describes and discusses the strength of evidence surrounding diagnostic categories for an in-office, clinical exam and checklist tool for LBP diagnosis. The use of a standardized tool for diagnosing low back pain in clinical and research settings is encouraged. PMID:23997245

Dual N-Back Working Memory Training in Healthy Adults: A Randomized Comparison to Processing Speed Training

PubMed Central

Lawlor-Savage, Linette; Goghari, Vina M.

2016-01-01

Enhancing cognitive ability is an attractive concept, particularly for middle-aged adults interested in maintaining cognitive functioning and preventing age-related declines. Computerized working memory training has been investigated as a safe method of cognitive enhancement in younger and older adults, although few studies have considered the potential impact of working memory training on middle-aged adults. This study investigated dual n-back working memory training in healthy adults aged 30–60. Fifty-seven adults completed measures of working memory, processing speed, and fluid intelligence before and after a 5-week web-based dual n-back or active control (processing speed) training program. Results: Repeated measures multivariate analysis of variance failed to identify improvements across the three cognitive composites, working memory, processing speed, and fluid intelligence, after training. Follow-up Bayesian analyses supported null findings for training effects for each individual composite. Findings suggest that dual n-back working memory training may not benefit working memory or fluid intelligence in healthy adults. Further investigation is necessary to clarify if other forms of working memory training may be beneficial, and what factors impact training-related benefits, should they occur, in this population. PMID:27043141

4. EXTERIOR OF SOUTH END OF BUILDING 104 SHOWING 1LIGHT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. EXTERIOR OF SOUTH END OF BUILDING 104 SHOWING 1-LIGHT SIDE EXIT DOOR AND ORIGINAL WOOD-FRAMED SLIDING GLASS KITCHEN WINDOWS AT PHOTO CENTER, AND TALL RUSTIC STYLE CHIMNEY WITH GABLE FRAME ON BACK WALL OF HOUSE. VIEW TO NORTHEAST. - Rush Creek Hydroelectric System, Worker Cottage, Rush Creek, June Lake, Mono County, CA

Cassegrain Solar Concentrator System for ISRU Material Processing

NASA Technical Reports Server (NTRS)

Colozza, Anthony J.; Macosko, Robert; Castle, Charles; Sacksteder, Kurt; Suzuki, Nantel H.; Mulherin, James

2012-01-01

A 0.5 m diameter Cassegrain concentrator was constructed as a means of providing highly concentrated sunlight for the demonstration processing of lunar simulated regolith and other NASA In-Situ Resource Utilization Project (ISRU) reaction processes. The concentrator is constructed of aluminum with a concentration ratio of approximately 3000 to 1. The concentrator focuses solar energy into a movable tray located behind the concentrator. This tray can hold simulated regolith or any other material and or device to be tested with concentrated solar energy. The tray is movable in one axis. A 2-axis extended optical system was also designed and fabricated. The extended optical system is added to the back of the primary concentrator in place of the moveable test tray and associated apparatus. With this optical system the focused sunlight can be extended from the back of the primary concentrator toward the ground with the added advantage of moving the focal point axially and laterally relative to the ground. This allows holding the focal point at a fixed position on the ground as the primary concentrator tracks the sun. Also, by design, the focal point size was reduced via the extended optics by a factor of 2 and results in a concentration ratio for the system of approximately 6,000 to 1.The designs of both optical systems are discussed. The results from simulated regolith melting tests are presented as well as the operational experience of utilizing the Cassegrain concentrator system.

Major system acquisitions process (A-109)

NASA Technical Reports Server (NTRS)

Saric, C.

1991-01-01

The Major System examined is a combination of elements (hardware, software, facilities, and services) that function together to produce capabilities required to fulfill a mission need. The system acquisition process is a sequence of activities beginning with documentation of mission need and ending with introduction of major system into operational use or otherwise successful achievement of program objectives. It is concluded that the A-109 process makes sense and provides a systematic, integrated management approach along with appropriate management level involvement and innovative and 'best ideas' from private sector in satisfying mission needs.

Recommended Computer End-User Skills for Business Students by Inc. 500 Executives and Office Systems Educators.

ERIC Educational Resources Information Center

Zhao, Jensen J.; Ray, Charles M.; Dye, Lee J.; Davis, Rodney

1998-01-01

Executives (n=63) and office-systems educators (n=88) recommended for workers the following categories of computer end-user skills: hardware, operating systems, word processing, spreadsheets, database, desktop publishing, and presentation. (SK)

Processable Polyimides Containing APB and Reactive End Caps

NASA Technical Reports Server (NTRS)

Jensen, Brian J.

2003-01-01

Imide copolymers that contain 1,3- bis(3-aminophenoxy)benzene (APB) and other diamines and dianhydrides and that are terminated with appropriate amounts of reactive end caps have been invented. The reactive end caps investigated thus far include 4-phenylethynyl phthalic anhydride (PEPA), 3- aminophenoxy-4-phenylethynylbenzop henone (3-APEB), maleic anhydride (MA), and 5-norbornene-2,3-dicarboxylic anhydride [also known as nadic anhydride (NA)]. The advantage of these copolyimides terminated with reactive groups, relative to other polyimides terminated with reactive groups, is a combination of (1) higher values of desired mechanical-property parameters and (2) greater ease of processing into useful parts.

An overview of recent end-to-end wireless medical video telemedicine systems using 3G.

PubMed

Panayides, A; Pattichis, M S; Pattichis, C S; Schizas, C N; Spanias, A; Kyriacou, E

2010-01-01

Advances in video compression, network technologies, and computer technologies have contributed to the rapid growth of mobile health (m-health) systems and services. Wide deployment of such systems and services is expected in the near future, and it's foreseen that they will soon be incorporated in daily clinical practice. This study focuses in describing the basic components of an end-to-end wireless medical video telemedicine system, providing a brief overview of the recent advances in the field, while it also highlights future trends in the design of telemedicine systems that are diagnostically driven.

"Dead End Kids in Dead End Jobs"? Reshaping Debates on Young People in Jobs without Training

ERIC Educational Resources Information Center

Quinn, Jocey; Lawy, Robert; Diment, Kim

2008-01-01

Young people who are in "jobs without training" (JWT) are commonly seen as "dead end kids in dead end jobs". They have been identified as a problem group who need to be encouraged back into formal education and training. Following the Leitch report and the new policy goal to involve all young people in education and training up…

Minimising back reflections from the common path objective in a fundus camera

NASA Astrophysics Data System (ADS)

Swat, A.

2016-11-01

Eliminating back reflections is critical in the design of a fundus camera with internal illuminating system. As there is very little light reflected from the retina, even excellent antireflective coatings are not sufficient suppression of ghost reflections, therefore the number of surfaces in the common optics in illuminating and imaging paths shall be minimised. Typically a single aspheric objective is used. In the paper an alternative approach, an objective with all spherical surfaces, is presented. As more surfaces are required, more sophisticated method is needed to get rid of back reflections. Typically back reflections analysis, comprise treating subsequent objective surfaces as mirrors, and reflections from the objective surfaces are traced back through the imaging path. This approach can be applied in both sequential and nonsequential ray tracing. It is good enough for system check but not very suitable for early optimisation process in the optical system design phase. There are also available standard ghost control merit function operands in the sequential ray-trace, for example in Zemax system, but these don't allow back ray-trace in an alternative optical path, illumination vs. imaging. What is proposed in the paper, is a complete method to incorporate ghost reflected energy into the raytracing system merit function for sequential mode which is more efficient in optimisation process. Although developed for the purpose of specific case of fundus camera, the method might be utilised in a wider range of applications where ghost control is critical.

A food environments feedback system (FoodBack) for empowering citizens and change agents to create healthier community food places.

PubMed

Vandevijvere, Stefanie; Williams, Rachel; Tawfiq, Essa; Swinburn, Boyd

2017-11-14

This study developed a systems-based approach (called FoodBack) to empower citizens and change agents to create healthier community food places. Formative evaluations were held with citizens and change agents in six diverse New Zealand communities, supplemented by semi-structured interviews with 85 change agents in Auckland and Hamilton in 2015-2016. The emerging system was additionally reviewed by public health experts from diverse organizations. A food environments feedback system was constructed to crowdsource key indicators of the healthiness of diverse community food places (i.e. schools, hospitals, supermarkets, fast food outlets, sport centers) and outdoor spaces (i.e. around schools), comments/pictures about barriers and facilitators to healthy eating and exemplar stories on improving the healthiness of food environments. All the information collected is centrally processed and translated into 'short' (immediate) and 'long' (after analyses) feedback loops to stimulate actions to create healthier food places. FoodBack, as a comprehensive food environment feedback system (with evidence databases and feedback and recognition processes), has the potential to increase food sovereignty, and generate a sustainable, fine-grained database of food environments for real-time food policy research. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Simple processing of back-contacted silicon heterojunction solar cells using selective-area crystalline growth

NASA Astrophysics Data System (ADS)

Tomasi, Andrea; Paviet-Salomon, Bertrand; Jeangros, Quentin; Haschke, Jan; Christmann, Gabriel; Barraud, Loris; Descoeudres, Antoine; Seif, Johannes Peter; Nicolay, Sylvain; Despeisse, Matthieu; de Wolf, Stefaan; Ballif, Christophe

2017-04-01

For crystalline-silicon solar cells, voltages close to the theoretical limit are nowadays readily achievable when using passivating contacts. Conversely, maximal current generation requires the integration of the electron and hole contacts at the back of the solar cell to liberate its front from any shadowing loss. Recently, the world-record efficiency for crystalline-silicon single-junction solar cells was achieved by merging these two approaches in a single device; however, the complexity of fabricating this class of devices raises concerns about their commercial potential. Here we show a contacting method that substantially simplifies the architecture and fabrication of back-contacted silicon solar cells. We exploit the surface-dependent growth of silicon thin films, deposited by plasma processes, to eliminate the patterning of one of the doped carrier-collecting layers. Then, using only one alignment step for electrode definition, we fabricate a proof-of-concept 9-cm2 tunnel-interdigitated back-contact solar cell with a certified conversion efficiency >22.5%.

[Nursing and the humanization of the end- of-life care within healthcare systems].

PubMed

Gómez Arca, Marina

2014-01-01

The reflection upon the humanisation of the end-of-life process within healthcare systems and the implication of healthcare professionals is the main objective of this article. The evolution of the model of care and nurses leadership role at the end-of-life process is evaluated. This analysis starts from the first European references regarding advance wills, made in 1997 at the Oviedo Convention, until the introduction of the idea of advance directives incorporated into Spanish law in 2002. It sets the concept of advance planning in health-related decisions, which establishes a process of voluntary dialogue where every person can clarify values, preferences and wishes regarding the final moments of life, with the support of the healthcare professionals. Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

Alternative Packaging for Back-Illuminated Imagers

NASA Technical Reports Server (NTRS)

Pain, Bedabrata

2009-01-01

An alternative scheme has been conceived for packaging of silicon-based back-illuminated, back-side-thinned complementary metal oxide/semiconductor (CMOS) and charge-coupled-device image-detector integrated circuits, including an associated fabrication process. This scheme and process are complementary to those described in "Making a Back-Illuminated Imager With Back-Side Connections" (NPO-42839), NASA Tech Briefs, Vol. 32, No. 7 (July 2008), page 38. To avoid misunderstanding, it should be noted that in the terminology of imaging integrated circuits, "front side" or "back side" does not necessarily refer to the side that, during operation, faces toward or away from a source of light or other object to be imaged. Instead, "front side" signifies that side of a semiconductor substrate upon which the pixel pattern and the associated semiconductor devices and metal conductor lines are initially formed during fabrication, and "back side" signifies the opposite side. If the imager is of the type called "back-illuminated," then the back side is the one that faces an object to be imaged. Initially, a back-illuminated, back-side-thinned image-detector is fabricated with its back side bonded to a silicon handle wafer. At a subsequent stage of fabrication, the front side is bonded to a glass wafer (for mechanical support) and the silicon handle wafer is etched away to expose the back side. The frontside integrated circuitry includes metal input/output contact pads, which are rendered inaccessible by the bonding of the front side to the glass wafer. Hence, one of the main problems is to make the input/output contact pads accessible from the back side, which is ultimately to be the side accessible to the external world. The present combination of an alternative packaging scheme and associated fabrication process constitute a solution of the problem.

Storage system software solutions for high-end user needs

NASA Technical Reports Server (NTRS)

Hogan, Carole B.

1992-01-01

Today's high-end storage user is one that requires rapid access to a reliable terabyte-capacity storage system running in a distributed environment. This paper discusses conventional storage system software and concludes that this software, designed for other purposes, cannot meet high-end storage requirements. The paper also reviews the philosophy and design of evolving storage system software. It concludes that this new software, designed with high-end requirements in mind, provides the potential for solving not only the storage needs of today but those of the foreseeable future as well.

End-to-End Information System design at the NASA Jet Propulsion Laboratory. [data transmission between user and space-based sensor

NASA Technical Reports Server (NTRS)

Hooke, A. J.

1978-01-01

In recognition of a pressing need of the 1980s to optimize the two-way flow of information between a ground-based user and a remote-space-based sensor, an end-to-end approach to the design of information systems has been adopted at the JPL. This paper reviews End-to-End Information System (EEIS) activity at the JPL, with attention given to the scope of the EEIS transfer function, and functional and physical elements of the EEIS. The relationship between the EEIS and the NASA End-to-End Data System program is discussed.

Potential Occupant Injury Reduction in Pre-Crash System Equipped Vehicles in the Striking Vehicle of Rear-end Crashes

PubMed Central

Kusano, Kristofer D.; Gabler, Hampton C.

2010-01-01

To mitigate the severity of rear-end and other collisions, Pre-Crash Systems (PCS) are being developed. These active safety systems utilize radar and/or video cameras to determine when a frontal crash, such as a front-to-back rear-end collisions, is imminent and can brake autonomously, even with no driver input. Of these PCS features, the effects of autonomous pre-crash braking are estimated. To estimate the maximum potential for injury reduction due to autonomous pre-crash braking in the striking vehicle of rear-end crashes, a methodology is presented for determining 1) the reduction in vehicle crash change in velocity (ΔV) due to PCS braking and 2) the number of injuries that could be prevented due to the reduction in collision severity. Injury reduction was only performed for belted drivers, as unbelted drivers have an unknown risk of being thrown out of position. The study was based on 1,406 rear-end striking vehicles from NASS / CDS years 1993 to 2008. PCS parameters were selected from realistic values and varied to examine the effect on system performance. PCS braking authority was varied from 0.5 G’s to 0.8 G’s while time to collision (TTC) was held at 0.45 seconds. TTC was then varied from 0.3 second to 0.6 seconds while braking authority was held constant at 0.6 G’s. A constant braking pulse (step function) and ramp-up braking pulse were used. The study found that automated PCS braking could reduce the crash ΔV in rear-end striking vehicles by an average of 12% – 50% and avoid 0% – 14% of collisions, depending on PCS parameters. Autonomous PCS braking could potentially reduce the number of injured drivers who are belted by 19% to 57%. PMID:21050603

Potential Occupant Injury Reduction in Pre-Crash System Equipped Vehicles in the Striking Vehicle of Rear-end Crashes.

PubMed

Kusano, Kristofer D; Gabler, Hampton C

2010-01-01

To mitigate the severity of rear-end and other collisions, Pre-Crash Systems (PCS) are being developed. These active safety systems utilize radar and/or video cameras to determine when a frontal crash, such as a front-to-back rear-end collisions, is imminent and can brake autonomously, even with no driver input. Of these PCS features, the effects of autonomous pre-crash braking are estimated. To estimate the maximum potential for injury reduction due to autonomous pre-crash braking in the striking vehicle of rear-end crashes, a methodology is presented for determining 1) the reduction in vehicle crash change in velocity (ΔV) due to PCS braking and 2) the number of injuries that could be prevented due to the reduction in collision severity. Injury reduction was only performed for belted drivers, as unbelted drivers have an unknown risk of being thrown out of position. The study was based on 1,406 rear-end striking vehicles from NASS / CDS years 1993 to 2008. PCS parameters were selected from realistic values and varied to examine the effect on system performance. PCS braking authority was varied from 0.5 G's to 0.8 G's while time to collision (TTC) was held at 0.45 seconds. TTC was then varied from 0.3 second to 0.6 seconds while braking authority was held constant at 0.6 G's. A constant braking pulse (step function) and ramp-up braking pulse were used. The study found that automated PCS braking could reduce the crash ΔV in rear-end striking vehicles by an average of 12% - 50% and avoid 0% - 14% of collisions, depending on PCS parameters. Autonomous PCS braking could potentially reduce the number of injured drivers who are belted by 19% to 57%.

A management system for end-of-life tyres: a Portuguese case study.

PubMed

Ferrão, Paulo; Ribeiro, Paulo; Silva, Paulo

2008-01-01

The European Union introduced several policy instruments based in the extended producer responsibility (EPR) in order to improve the environmental performance of products and services through their life cycles. In this context, the Portuguese government decided to apply the EPR concept to tyres, and producers were obliged to constitute an end-of-life management system to promote the collection, recycling and reuse of end-of-life (EOL) tyres. This required producers, distributors, recyclers and retreaders to be identified and characterized, and local processing infrastructures to be analyzed. The information was used to design an economically optimised EOL tyre management system while promoting the activity of all EOL operators in order for the imposed collecting and recovery targets to be fulfilled. This paper discusses the interaction between the different governmental, private and academic institutions for the creation of the integrated management system for EOL tyres, the approach taken, the technical, political and legal aspects underneath them, as well as the environmental consequences induced by the creation of the management system. The results obtained during the first years of operation are reported and show an increase in the collection and recycling of EOL tyres and the consolidation of the collection and processing infrastructures.

The Effects of Antifoam Agent on Dead End Filtration Process

NASA Astrophysics Data System (ADS)

Mohamad Pauzi, S.; Ahmad, N.; Yahya, M. F.; Arifin, M. A.

2018-05-01

The formation of foam as a result from introducing gases during cell culture process in the bioprocess industry has indirectly affected the throughput of the product of interest. Due to that, antifoams were developed and established as one of the means to minimize the formation of foam in the cell culture. There are many types of antifoams but the silicone-type of antifoams are widely used in the bioprocess industry. Although the establishment of antifoam has aided the cell culture process, the impacts of its presence in the cell culture to the downstream process especially the dead end filtration is not widely discussed. The findings in the study emphasized on the dead end filtration performance that includes flux rate profile and the resulted filtration capacity. In this study, the concentrations of antifoam injected into the solution were varied from 0.2% v/v – 1.0% v/v and the solutions were filtered using constant flow method. The resulted maximum pressure readings and final flux rates indicated that the resistance exerted to the feed flow rate increased as the concentration of antifoam loaded in the solution increased. This later has led to the decline in the flux rates with percentage reduction between 32 – 68%. The calculated filter capacity for flux rate of 1000LMH ranged from 53 – 63L/m2 while it is in the range of 40 – 43L/m2 for flux rate of 2000LMH. The presence of antifoam agents in the feed load was determined to have negative effects on the dead end filtration performance and it may reduce the efficiency of the dead end filtration process.

Physician perspectives on legal processes for resolving end-of-life disputes.

PubMed

Chidwick, Paula; Sibbald, Robert

2011-01-01

In order to understand how to effectively approach end-of-life disputes, this study surveyed physicians' attitudes towards one process for resolving end-of-life disputes, namely, the Consent and Capacity Board of Ontario. In this case, the process involved examining interpretation of best interests between substitute decision-makers and medical teams. Physicians who made "Form G" applications to the Consent and Capacity Board of Ontario that resulted in a decision posted on the open-access database, Canadian Legal Information Institute (CanLii), were identified and surveyed. This purposive sample led to 13 invitations to participate and 12 interviews (92% response rate). Interviews were conducted using a prescribed interview guide. No barriers to the Consent and Capacity Board process were reported. Applications were made when physicians reached an impasse with the family and further treatment was perceived to be "unethical." The most significant challenge reported was the delay when appeals were launched. Appeals extended the process for an indefinite period of time making it so lengthy it negated any perceived benefits of the process. Benefits included that a neutral third party, namely the Consent and Capacity Board, was able to assess best interests. Also, when decisions were timely, further harm to the patient was minimized. Physicians reported this particular approach, namely the Consent and Capacity Board has a mechanism that is worthwhile, patient centred, process oriented, orderly and efficient for resolving end-of-life disputes and, in particular, determining best interests. However, unless the appeal process can be adjusted to respond to the ICU context there is a risk of not serving the best interest of patients. Physicians would recommend framing end-of-life treatment plans in the positive instead of negative, for example, propose palliative care and no escalation of treatment as opposed to withdrawal.

End-to-end system test for solid-state microdosemeters.

PubMed

Pisacane, V L; Dolecek, Q E; Malak, H; Dicello, J F

2010-08-01

The gold standard in microdosemeters has been the tissue equivalent proportional counter (TEPC) that utilises a gas cavity. An alternative is the solid-state microdosemeter that replaces the gas with a condensed phase (silicon) detector with microscopic sensitive volumes. Calibrations of gas and solid-state microdosemeters are generally carried out using radiation sources built into the detector that impose restrictions on their handling, transportation and licensing in accordance with the regulations from international, national and local nuclear regulatory bodies. Here a novel method is presented for carrying out a calibration and end-to-end system test of a microdosemeter using low-energy photons as the initiating energy source, thus obviating the need for a regulated ionising radiation source. This technique may be utilised to calibrate both a solid-state microdosemeter and, with modification, a TEPC with the higher average ionisation energy of a gas.

Aerodynamic Characteristics and Glide-Back Performance of Langley Glide-Back Booster

NASA Technical Reports Server (NTRS)

Pamadi, Bandu N.; Covell, Peter F.; Tartabini, Paul V.; Murphy, Kelly J.

2004-01-01

NASA-Langley Research Center is conducting system level studies on an-house concept of a small launch vehicle to address NASA's needs for rapid deployment of small payloads to Low Earth Orbit. The vehicle concept is a three-stage system with a reusable first stage and expendable upper stages. The reusable first stage booster, which glides back to launch site after staging around Mach 3 is named the Langley Glide-Back Booster (LGBB). This paper discusses the aerodynamic characteristics of the LGBB from subsonic to supersonic speeds, development of the aerodynamic database and application of this database to evaluate the glide back performance of the LGBB. The aerodynamic database was assembled using a combination of wind tunnel test data and engineering level analysis. The glide back performance of the LGBB was evaluated using a trajectory optimization code and subject to constraints on angle of attack, dynamic pressure and normal acceleration.

Solution processed flexible organic thin film back-gated transistors based on polyimide dielectric films

NASA Astrophysics Data System (ADS)

Park, Janghoon; Min, Yoonki; Lee, Dongjin

2018-04-01

An organic thin film back-gated transistor (OBGT) was fabricated and characterized. The gate electrode was printed on the back side of substrate, and the dielectric layer was omitted by substituting the dielectric layer with the polyimide (PI) film substrate. Roll-to-roll (R2R) gravure printing, doctor blading, and drop casting methods were used to fabricate the OBGT. The printed OBGT device shows better performance compared with an OTFT device based on dielectric layer of BaTiO3. Additionally, a calendering process enhanced the performance by a factor of 3 to 7 (mobility: 0.016 cm2/V.s, on/off ratio: 9.17×103). A bending test was conducted to confirm the flexibility and durability of the OBGT device. The results show the fabricated device endures 20000-cyclic motions. The realized OBGT device was successfully fabricated and working, which is meaningful for production engineering from the viewpoint of process development.

Scaled CMOS Reliability and Considerations for Spacecraft Systems: Bottom-Up and Top-Down Perspective

NASA Technical Reports Server (NTRS)

White, Mark

2012-01-01

New space missions will increasingly rely on more advanced technologies because of system requirements for higher performance, particularly in instruments and high-speed processing. Component-level reliability challenges with scaled CMOS in spacecraft systems from a bottom-up perspective have been presented. Fundamental Front-end and Back-end processing reliability issues with more aggressively scaled parts have been discussed. Effective thermal management from system-level to the componentlevel (top-down) is a key element in overall design of reliable systems. Thermal management in space systems must consider a wide range of issues, including thermal loading of many different components, and frequent temperature cycling of some systems. Both perspectives (top-down and bottom-up) play a large role in robust, reliable spacecraft system design.

End-to-end network models encompassing terrestrial, wireless, and satellite components

NASA Astrophysics Data System (ADS)

Boyarko, Chandler L.; Britton, John S.; Flores, Phil E.; Lambert, Charles B.; Pendzick, John M.; Ryan, Christopher M.; Shankman, Gordon L.; Williams, Ramon P.

2004-08-01

Development of network models that reflect true end-to-end architectures such as the Transformational Communications Architecture need to encompass terrestrial, wireless and satellite component to truly represent all of the complexities in a world wide communications network. Use of best-in-class tools including OPNET, Satellite Tool Kit (STK), Popkin System Architect and their well known XML-friendly definitions, such as OPNET Modeler's Data Type Description (DTD), or socket-based data transfer modules, such as STK/Connect, enable the sharing of data between applications for more rapid development of end-to-end system architectures and a more complete system design. By sharing the results of and integrating best-in-class tools we are able to (1) promote sharing of data, (2) enhance the fidelity of our results and (3) allow network and application performance to be viewed in the context of the entire enterprise and its processes.

Making a Back-Illuminated Imager with Back-Side Contact and Alignment Markers

NASA Technical Reports Server (NTRS)

Pain, Bedabrata

2008-01-01

A design modification and a fabrication process that implements the modification have been conceived to solve two problems encountered in the development of back-illuminated, back-sidethinned complementary metal oxide/ semiconductor (CMOS) image-detector integrated circuits. The two problems are (1) how to form metal electrical-contact pads on the back side that are electrically connected through the thickness in proper alignment with electrical contact points on the front side and (2) how to provide alignment keys on the back side to ensure proper registration of backside optical components (e.g., microlenses and/or color filters) with the front-side pixel pattern. The essence of the design modification is to add metal plugs that extend from the desired front-side locations through the thickness and protrude from the back side of the substrate. The plugs afford the required front-to-back electrical conduction, and the protrusions of the plugs serve as both the alignment keys and the bases upon which the back-side electrical-contact pads can be formed.

2. JoAnn SieburgBaker, Photographer, September 1977. SECTION SHOWING BACK OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. JoAnn Sieburg-Baker, Photographer, September 1977. SECTION SHOWING BACK OF ROUNDHOUSE AND END OF BACK SHOP WHERE CRANE WAS LOCATED. - Southern Railway Company, Spencer Shops, Salisbury Avenue between Third and Eight Streets, Spencer, Rowan County, NC

CHEETAH: circuit-switched high-speed end-to-end transport architecture

NASA Astrophysics Data System (ADS)

Veeraraghavan, Malathi; Zheng, Xuan; Lee, Hyuk; Gardner, M.; Feng, Wuchun

2003-10-01

Leveraging the dominance of Ethernet in LANs and SONET/SDH in MANs and WANs, we propose a service called CHEETAH (Circuit-switched High-speed End-to-End Transport ArcHitecture). The service concept is to provide end hosts with high-speed, end-to-end circuit connectivity on a call-by-call shared basis, where a "circuit" consists of Ethernet segments at the ends that are mapped into Ethernet-over-SONET long-distance circuits. This paper focuses on the file-transfer application for such circuits. For this application, the CHEETAH service is proposed as an add-on to the primary Internet access service already in place for enterprise hosts. This allows an end host that is sending a file to first attempt setting up an end-to-end Ethernet/EoS circuit, and if rejected, fall back to the TCP/IP path. If the circuit setup is successful, the end host will enjoy a much shorter file-transfer delay than on the TCP/IP path. To determine the conditions under which an end host with access to the CHEETAH service should attempt circuit setup, we analyze mean file-transfer delays as a function of call blocking probability in the circuit-switched network, probability of packet loss in the IP network, round-trip times, link rates, and so on.

Delta-Doped Back-Illuminated CMOS Imaging Arrays: Progress and Prospects

NASA Technical Reports Server (NTRS)

Hoenk, Michael E.; Jones, Todd J.; Dickie, Matthew R.; Greer, Frank; Cunningham, Thomas J.; Blazejewski, Edward; Nikzad, Shouleh

2009-01-01

In this paper, we report the latest results on our development of delta-doped, thinned, back-illuminated CMOS imaging arrays. As with charge-coupled devices, thinning and back-illumination are essential to the development of high performance CMOS imaging arrays. Problems with back surface passivation have emerged as critical to the prospects for incorporating CMOS imaging arrays into high performance scientific instruments, just as they did for CCDs over twenty years ago. In the early 1990's, JPL developed delta-doped CCDs, in which low temperature molecular beam epitaxy was used to form an ideal passivation layer on the silicon back surface. Comprising only a few nanometers of highly-doped epitaxial silicon, delta-doping achieves the stability and uniformity that are essential for high performance imaging and spectroscopy. Delta-doped CCDs were shown to have high, stable, and uniform quantum efficiency across the entire spectral range from the extreme ultraviolet through the near infrared. JPL has recently bump-bonded thinned, delta-doped CMOS imaging arrays to a CMOS readout, and demonstrated imaging. Delta-doped CMOS devices exhibit the high quantum efficiency that has become the standard for scientific-grade CCDs. Together with new circuit designs for low-noise readout currently under development, delta-doping expands the potential scientific applications of CMOS imaging arrays, and brings within reach important new capabilities, such as fast, high-sensitivity imaging with parallel readout and real-time signal processing. It remains to demonstrate manufacturability of delta-doped CMOS imaging arrays. To that end, JPL has acquired a new silicon MBE and ancillary equipment for delta-doping wafers up to 200mm in diameter, and is now developing processes for high-throughput, high yield delta-doping of fully-processed wafers with CCD and CMOS imaging devices.

Fighting back against America's public health enemy number one.

PubMed Central

Spickard, W. A.; Dixon, G. L.; Sarver, F. W.

1994-01-01

Fighting Back is a comprehensive substance abuse program operating in 14 communities spread throughout the United States. The Robert Wood Johnson Foundation has committed more than $45 million over a 7-year period to plan and implement innovative, community-wide initiatives in Columbia, SC; Charlotte, NC; Kansas City, Mo; Little Rock, Ark; Northwest New Mexico; Milwaukee, Wis; New Haven, Conn; Newark, NJ; Oakland, Calif; San Antonio, Tex; Santa Barbara, Calif; Vallejo, Calif; Washington, DC; and Worcester, Mass. In this article the work in progress at the end of 18 months of a 5-year implementation program in each site is reported. A Fighting Back National Program Office operates from a base at Vanderbilt University Medical Center in Nashville, Tenn. The senior staff of this office highlights the process that has unfolded to date, describes some of the sources of encouragement, and discusses some of the critical issues and sources of concern. A "Call to Action" on the part of the federal government is included. PMID:8069272

CLIMLAB: a Python-based software toolkit for interactive, process-oriented climate modeling

NASA Astrophysics Data System (ADS)

Rose, B. E. J.

2015-12-01

Global climate is a complex emergent property of the rich interactions between simpler components of the climate system. We build scientific understanding of this system by breaking it down into component process models (e.g. radiation, large-scale dynamics, boundary layer turbulence), understanding each components, and putting them back together. Hands-on experience and freedom to tinker with climate models (whether simple or complex) is invaluable for building physical understanding. CLIMLAB is an open-ended software engine for interactive, process-oriented climate modeling. With CLIMLAB you can interactively mix and match model components, or combine simpler process models together into a more comprehensive model. It was created primarily to support classroom activities, using hands-on modeling to teach fundamentals of climate science at both undergraduate and graduate levels. CLIMLAB is written in Python and ties in with the rich ecosystem of open-source scientific Python tools for numerics and graphics. The IPython notebook format provides an elegant medium for distributing interactive example code. I will give an overview of the current capabilities of CLIMLAB, the curriculum we have developed thus far, and plans for the future. Using CLIMLAB requires some basic Python coding skills. We consider this an educational asset, as we are targeting upper-level undergraduates and Python is an increasingly important language in STEM fields. However CLIMLAB is well suited to be deployed as a computational back-end for a graphical gaming environment based on earth-system modeling.

A front-end wafer-level microsystem packaging technique with micro-cap array

NASA Astrophysics Data System (ADS)

Chiang, Yuh-Min

2002-09-01

The back-end packaging process is the remaining challenge for the micromachining industry to commercialize microsystem technology (MST) devices at low cost. This dissertation presents a novel wafer level protection technique as a final step of the front-end fabrication process for MSTs. It facilitates improved manufacturing throughput and automation in package assembly, wafer level testing of devices, and enhanced device performance. The method involves the use of a wafer-sized micro-cap array, which consists of an assortment of small caps micro-molded onto a material with adjustable shapes and sizes to serve as protective structures against the hostile environments during packaging. The micro-cap array is first constructed by a micromachining process with micro-molding technique, then sealed to the device wafer at wafer level. Epoxy-based wafer-level micro cap array has been successfully fabricated and showed good compatibility with conventional back-end packaging processes. An adhesive transfer technique was demonstrated to seal the micro cap array with a MEMS device wafer. No damage or gross leak was observed while wafer dicing or later during a gross leak test. Applications of the micro cap array are demonstrated on MEMS, microactuators fabricated using CRONOS MUMPS process. Depending on the application needs, the micro-molded cap can be designed and modified to facilitate additional component functions, such as optical, electrical, mechanical, and chemical functions, which are not easily achieved in the device by traditional means. Successful fabrication of a micro cap array comprised with microlenses can provide active functions as well as passive protection. An optical tweezer array could be one possibility for applications of a micro cap with microlenses. The micro cap itself could serve as micro well for DNA or bacteria amplification as well.

Engineering of Data Acquiring Mobile Software and Sustainable End-User Applications

NASA Technical Reports Server (NTRS)

Smith, Benton T.

2013-01-01

The criteria for which data acquiring software and its supporting infrastructure should be designed should take the following two points into account: the reusability and organization of stored online and remote data and content, and an assessment on whether abandoning a platform optimized design in favor for a multi-platform solution significantly reduces the performance of an end-user application. Furthermore, in-house applications that control or process instrument acquired data for end-users should be designed with a communication and control interface such that the application's modules can be reused as plug-in modular components in greater software systems. The application of the above mentioned is applied using two loosely related projects: a mobile application, and a website containing live and simulated data. For the intelligent devices mobile application AIDM, the end-user interface have a platform and data type optimized design, while the database and back-end applications store this information in an organized manner and manage access to that data to only to authorized user end application(s). Finally, the content for the website was derived from a database such that the content can be included and uniform to all applications accessing the content. With these projects being ongoing, I have concluded from my research that the applicable methods presented are feasible for both projects, and that a multi-platform design for the mobile application only marginally drop the performance of the mobile application.

Paging memory from random access memory to backing storage in a parallel computer

DOEpatents

Archer, Charles J; Blocksome, Michael A; Inglett, Todd A; Ratterman, Joseph D; Smith, Brian E

2013-05-21

Paging memory from random access memory (`RAM`) to backing storage in a parallel computer that includes a plurality of compute nodes, including: executing a data processing application on a virtual machine operating system in a virtual machine on a first compute node; providing, by a second compute node, backing storage for the contents of RAM on the first compute node; and swapping, by the virtual machine operating system in the virtual machine on the first compute node, a page of memory from RAM on the first compute node to the backing storage on the second compute node.

Low-Power Analog Processing for Sensing Applications: Low-Frequency Harmonic Signal Classification

PubMed Central

White, Daniel J.; William, Peter E.; Hoffman, Michael W.; Balkir, Sina

2013-01-01

A low-power analog sensor front-end is described that reduces the energy required to extract environmental sensing spectral features without using Fast Fouriér Transform (FFT) or wavelet transforms. An Analog Harmonic Transform (AHT) allows selection of only the features needed by the back-end, in contrast to the FFT, where all coefficients must be calculated simultaneously. We also show that the FFT coefficients can be easily calculated from the AHT results by a simple back-substitution. The scheme is tailored for low-power, parallel analog implementation in an integrated circuit (IC). Two different applications are tested with an ideal front-end model and compared to existing studies with the same data sets. Results from the military vehicle classification and identification of machine-bearing fault applications shows that the front-end suits a wide range of harmonic signal sources. Analog-related errors are modeled to evaluate the feasibility of and to set design parameters for an IC implementation to maintain good system-level performance. Design of a preliminary transistor-level integrator circuit in a 0.13 μm complementary metal-oxide-silicon (CMOS) integrated circuit process showed the ability to use online self-calibration to reduce fabrication errors to a sufficiently low level. Estimated power dissipation is about three orders of magnitude less than similar vehicle classification systems that use commercially available FFT spectral extraction. PMID:23892765

End-To-End performance test of the LINC-NIRVANA Wavefront-Sensor system.

NASA Astrophysics Data System (ADS)

Berwein, Juergen; Bertram, Thomas; Conrad, Al; Briegel, Florian; Kittmann, Frank; Zhang, Xiangyu; Mohr, Lars

2011-09-01

LINC-NIRVANA is an imaging Fizeau interferometer, for use in near infrared wavelengths, being built for the Large Binocular Telescope. Multi-conjugate adaptive optics (MCAO) increases the sky coverage and the field of view over which diffraction limited images can be obtained. For its MCAO implementation, Linc-Nirvana utilizes four total wavefront sensors; each of the two beams is corrected by both a ground-layer wavefront sensor (GWS) and a high-layer wavefront sensor (HWS). The GWS controls the adaptive secondary deformable mirror (DM), which is based on an DSP slope computing unit. Whereas the HWS controls an internal DM via computations provided by an off-the-shelf multi-core Linux system. Using wavefront sensor data collected from a prior lab experiment, we have shown via simulation that the Linux based system is sufficient to operate at 1kHz, with jitter well below the needs of the final system. Based on that setup we tested the end-to-end performance and latency through all parts of the system which includes the camera, the wavefront controller, and the deformable mirror. We will present our loop control structure and the results of those performance tests.

Centrifugal contactor modified for end stage operation in a multistage system

DOEpatents

Jubin, Robert T.

1990-01-01

A cascade formed of a plurality of centrifugal contactors useful for countercurrent solvent extraction processes such as utilizable for the reprocessing of nuclear reactor fuels is modified to permit operation in the event one or both end stages of the cascade become inoperative. Weir assemblies are connected to each of the two end stages by suitable conduits for separating liquids discharged from an inoperative end stage based upon the weight of the liquid phases uses in the solvent extraction process. The weir assembly at one end stage is constructed to separate and discharge the heaviest liquid phase while the weir assembly at the other end stage is constructed to separate and discharge the lightest liquid phase. These weir assemblies function to keep the liquid discharge from an inoperative end stages on the same weight phase a would occur from an operating end stage.

Field experiment on CO2 back-production at the Ketzin pilot site

NASA Astrophysics Data System (ADS)

Martens, Sonja; Möller, Fabian; Schmidt-Hattenberger, Cornelia; Streibel, Martin; Szizybalski, Alexandra; Liebscher, Axel

2015-04-01

indicates that a safe back-production of CO2 is generally feasible and can be performed at both, stable reservoir and wellbore conditions. ERT monitoring shows that the geoelectrical array at the production well was capable of tracking the back-production process, e.g. the back-flow of brine into the parts formerly filled with CO2. Preliminary results also show that the back-produced CO2 at Ketzin has a purity > 97 per cent. Secondary component in the CO2 stream is N2 with < 3 per cent which probably results from former injection operation and field tests. The results will help to verify geochemical laboratory experiments which are typically performed in simplified synthetic systems. The results gained at the Ketzin site refer to the pilot scale. Upscaling of the results to industrial scale is possible but must first be tested and validated at demo projects.

An end-to-end secure patient information access card system.

PubMed

Alkhateeb, A; Singer, H; Yakami, M; Takahashi, T

2000-03-01

The rapid development of the Internet and the increasing interest in Internet-based solutions has promoted the idea of creating Internet-based health information applications. This will force a change in the role of IC cards in healthcare card systems from a data carrier to an access key medium. At the Medical Informatics Department of Kyoto University Hospital we are developing a smart card patient information project where patient databases are accessed via the Internet. Strong end-to-end data encryption is performed via Secure Socket Layers, transparent to transmit patient information. The smart card is playing the crucial role of access key to the database: user authentication is performed internally without ever revealing the actual key. For easy acceptance by healthcare professionals, the user interface is integrated as a plug-in for two familiar Web browsers, Netscape Navigator and MS Internet Explorer.

Ends-in Vs. Ends-Out Recombination in Yeast

PubMed Central

Hastings, P. J.; McGill, C.; Shafer, B.; Strathern, J. N.

1993-01-01

Integration of linearized plasmids into yeast chromosomes has been used as a model system for the study of recombination initiated by double-strand breaks. The linearized plasmid DNA recombines efficiently into sequences homologous to the ends of the DNA. This efficient recombination occurs both for the configuration in which the break is in a contiguous region of homology (herein called the ends-in configuration) and for ``omega'' insertions in which plasmid sequences interrupt a linear region of homology (herein called the ends-out configuration). The requirements for integration of these two configurations are expected to be different. We compared these two processes in a yeast strain containing an ends-in target and an ends-out target for the same cut plasmid. Recovery of ends-in events exceeds ends-out events by two- to threefold. Possible causes for the origin of this small bias are discussed. The lack of an extreme difference in frequency implies that cooperativity between the two ends does not contribute to the efficiency with which cut circular plasmids are integrated. This may also be true for the repair of chromosomal double-strand breaks. PMID:8307337

40 CFR 63.494 - Back-end process provisions-residual organic HAP and emission limitations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... producing butyl rubber, epichlorohydrin elastomer, neoprene, and nitrile butadiene rubber shall not exceed... processes at affected sources producing butyl rubber, epichlorohydrin elastomer, neoprene, and nitrile... submitted in accordance with § 63.499(f)(1). (i) For butyl rubber, the organic HAP emission limitation shall...

40 CFR 63.499 - Back-end process provisions-reporting.

Code of Federal Regulations, 2011 CFR

2011-07-01

... design (i.e., steam-assisted, air-assisted, or non-assisted); all visible emission readings, heat content... specify appropriate reporting and recordkeeping requirements as part of the review of the Precompliance...

40 CFR 63.499 - Back-end process provisions-reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... design (i.e., steam-assisted, air-assisted, or non-assisted); all visible emission readings, heat content... specify appropriate reporting and recordkeeping requirements as part of the review of the Precompliance...

40 CFR 63.499 - Back-end process provisions-reporting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... heater. (i) The flare design (i.e., steam-assisted, air-assisted, or non-assisted); all visible emission... Administrator will specify appropriate reporting and recordkeeping requirements as part of the review of the...

40 CFR 63.499 - Back-end process provisions-reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... design (i.e., steam-assisted, air-assisted, or non-assisted); all visible emission readings, heat content... specify appropriate reporting and recordkeeping requirements as part of the review of the Precompliance...

40 CFR 63.499 - Back-end process provisions-reporting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... design (i.e., steam-assisted, air-assisted, or non-assisted); all visible emission readings, heat content... specify appropriate reporting and recordkeeping requirements as part of the review of the Precompliance...

40 CFR 63.498 - Back-end process provisions-recordkeeping.

Code of Federal Regulations, 2011 CFR

2011-07-01

... be the crumb rubber dry weight of the rubber leaving the stripper. (iv) The organic HAP content of... be the crumb rubber dry weight of the crumb rubber leaving the stripper. (iii) The hourly average of... test runs. (1) The uncontrolled residual organic HAP content in the latex or dry crumb rubber, as...

40 CFR 63.498 - Back-end process provisions-recordkeeping.

Code of Federal Regulations, 2012 CFR

2012-07-01

... be the crumb rubber dry weight of the rubber leaving the stripper. (iv) The organic HAP content of... be the crumb rubber dry weight of the crumb rubber leaving the stripper. (iii) The hourly average of... test runs. (1) The uncontrolled residual organic HAP content in the latex or dry crumb rubber, as...

40 CFR 63.498 - Back-end process provisions-recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-07-01

... be the crumb rubber dry weight of the rubber leaving the stripper. (iv) The organic HAP content of... be the crumb rubber dry weight of the crumb rubber leaving the stripper. (iii) The hourly average of... test runs. (1) The uncontrolled residual organic HAP content in the latex or dry crumb rubber, as...

40 CFR 63.498 - Back-end process provisions-recordkeeping.

Code of Federal Regulations, 2013 CFR

2013-07-01

... be the crumb rubber dry weight of the rubber leaving the stripper. (iv) The organic HAP content of... be the crumb rubber dry weight of the crumb rubber leaving the stripper. (iii) The hourly average of... test runs. (1) The uncontrolled residual organic HAP content in the latex or dry crumb rubber, as...

A UNIX-based real-time data acquisition system for microprobe analysis using an advanced X11 window toolkit

NASA Astrophysics Data System (ADS)

Kramer, J. L. A. M.; Ullings, A. H.; Vis, R. D.

1993-05-01

A real-time data acquisition system for microprobe analysis has been developed at the Free University of Amsterdam. The system is composed of two parts: a front-end real-time and a back-end monitoring system. The front-end consists of a VMEbus based system which reads out a CAMAC crate. The back-end is implemented on a Sun work station running the UNIX operating system. This separation allows the integration of a minimal, and consequently very fast, real-time executive within the sophisticated possibilities of advanced UNIX work stations.

Pharmacists' views on implementing a disease state management program for low back pain.

PubMed

Abdel Shaheed, Christina; Maher, Christopher G; Williams, Kylie A; McLachlan, Andrew J

2016-01-01

Pharmacists have the potential to take a lead role in the primary care management of people with acute low back pain. The aim of this study was to investigate pharmacists' views on implementing a care program for people with acute low back pain in the community pharmacy. Recruitment of pharmacists for this study took place between July 2012 and March 2013. A convenience sample of 30 pharmacists who collaborated in recruiting participants for a low back pain clinical trial in Sydney (n=15 pharmacist recruiters and n=15 non-recruiters) completed an open-ended questionnaire. There was no marked variation in responses between the two groups. Participating pharmacists were receptive to the idea of implementing a care program for people with low back pain, highlighting the need for adequate reimbursement and adequate training of staff to ensure it is successful. Pharmacists identified that the follow up of people receiving such a service is dependent on several factors such as effective reminder systems and the proximity of patients to the pharmacy.

The relationship beween posture and back muscle endurance in industrial workers with flexion-related low back pain.

PubMed

O'Sullivan, Peter B; Mitchell, Tim; Bulich, Paul; Waller, Rob; Holte, Johan

2006-11-01

This preliminary cross-sectional study was undertaken to determine if there were measurable relationships between posture, back muscle endurance and low back pain (LBP) in industrial workers with a reported history of flexion strain injury and flexion pain provocation. Clinical reports state that subjects with flexion pain disorders of the lumbar spine commonly adopt passive flexed postures such as slump sitting and present with associated dysfunction of the spinal postural stabilising musculature. However, to date there is little empirical evidence to support that patients with back pain, posture their spines differently than pain-free subjects. Subjects included 21 healthy industrial workers and 24 industrial workers with flexion-provoked LBP. Lifestyle information, lumbo-pelvic posture in sitting, standing and lifting, and back muscle endurance were measured. LBP subjects had significantly reduced back muscle endurance (P < 0.01). LBP subjects sat with less hip flexion, (P = 0.05), suggesting increased posterior pelvic tilt in sitting. LBP subjects postured their spines significantly closer to their end of range lumbar flexion in 'usual' sitting than the healthy controls (P < 0.05). Correlations between increased time spent sitting, physical inactivity and poorer back muscle endurance were also identified. There were no significant differences found between the groups for the standing and lifting posture measures. These preliminary results support that a relationship may exist between flexed spinal postures, reduced back muscle endurance, physical inactivity and LBP in subjects with a history of flexion injury and pain.

Optimizing nursing care delivery systems in the Army: back to basics with care teams and peer feedback.

PubMed

Prue-Owens, Kathy; Watkins, Miko; Wolgast, Kelly A

2011-01-01

The Patient CaringTouch System emerged from a comprehensive assessment and gap analysis of clinical nursing capabilities in the Army. The Patient CaringTouch System now provides the framework and set of standards by which we drive excellence in quality nursing care for our patients and excellence in quality of life for our nurses in Army Medicine. As part of this enterprise transformation, we placed particular emphasis on the delivery of nursing care at the bedside as well as the integration of a formal professional peer feedback process in support of individual nurse practice enhancement. The Warrior Care Imperative Action Team was chartered to define and establish the standards for care teams in the clinical settings and the process by which we established formal peer feedback for our professional nurses. This back-to-basics approach is a cornerstone of the Patient CaringTouch System implementation and sustainment.

Augmented Feedback System to Support Physical Therapy of Non-specific Low Back Pain

NASA Astrophysics Data System (ADS)

Brodbeck, Dominique; Degen, Markus; Stanimirov, Michael; Kool, Jan; Scheermesser, Mandy; Oesch, Peter; Neuhaus, Cornelia

Low back pain is an important problem in industrialized countries. Two key factors limit the effectiveness of physiotherapy: low compliance of patients with repetitive movement exercises, and inadequate awareness of patients of their own posture. The Backtrainer system addresses these problems by real-time monitoring of the spine position, by providing a framework for most common physiotherapy exercises for the low back, and by providing feedback to patients in a motivating way. A minimal sensor configuration was identified as two inertial sensors that measure the orientation of the lower back at two points with three degrees of freedom. The software was designed as a flexible platform to experiment with different hardware, and with various feedback modalities. Basic exercises for two types of movements are provided: mobilizing and stabilizing. We developed visual feedback - abstract as well as in the form of a virtual reality game - and complemented the on-screen graphics with an ambient feedback device. The system was evaluated during five weeks in a rehabilitation clinic with 26 patients and 15 physiotherapists. Subjective satisfaction of subjects was good, and we interpret the results as encouraging indication for the adoption of such a therapy support system by both patients and therapists.

The Impact of Biofilms on the Process of Back Diffusion From a Contaminated Rock Matrix

NASA Astrophysics Data System (ADS)

Yungwirth, G. A.; Novakowski, K. S.; Ross, N.

2005-12-01

Groundwater remediation in fractured rock settings is complicated by the diffusion of contaminants into the rock matrix and the subsequent back diffusion into the fractures. The process of back diffusion, in particular, leads to extended periods of low-level contamination in the fracture network that persists long after the source area is hydraulically or otherwise removed. In such a case, we hypothesize that back diffusion could be limited by growing a biofilm which coats the rock fracture surface and potentially invades the rock micropores. This would effectively sequester the contamination potentially in perpetuity. To explore the viability of this concept, diffusion experiments were conducted in which the effect of biofilm growth on diffusion through thin (0.8 to 1.2 cm) slices of dolostone core obtained from the Lockport Formation, Southern Ontario, was investigated. The experiments were conducted using a double-cell method, in which the core slices were encapsulated inside Teflon coated hydraulic hose, fitted with ultra high molecular weight polyethylene endcaps having stainless steel sample ports. Diffusion was established across the core slice by spiking one reservoir with a conservative tracer and monitoring the tracer arrival in the reservoir located on the other side of the coupon. The experiments were conducted both in the presence and absence of a biofilm. Biofilm was grown on the rock coupons in a separate bath before the coupons were transferred to the apparatus for the diffusion experiments. Microbial populations indigenous to the groundwater used in the bath were stimulated to form the biofilm with the addition of a beef extract and peptone nutrient broth in 1g/L concentration. The extent of biofilm growth was monitored using a modified Dubois et al (1956) colorimetric method for sugar determination. Results were simulated using an analytical model that was developed for the geometry of the diffusion experiments. Governing equations for the model

Active Hearing Mechanisms Inspire Adaptive Amplification in an Acoustic Sensor System.

PubMed

Guerreiro, Jose; Reid, Andrew; Jackson, Joseph C; Windmill, James F C

2018-06-01

Over many millions of years of evolution, nature has developed some of the most adaptable sensors and sensory systems possible, capable of sensing, conditioning and processing signals in a very power- and size-effective manner. By looking into biological sensors and systems as a source of inspiration, this paper presents the study of a bioinspired concept of signal processing at the sensor level. By exploiting a feedback control mechanism between a front-end acoustic receiver and back-end neuronal based computation, a nonlinear amplification with hysteretic behavior is created. Moreover, the transient response of the front-end acoustic receiver can also be controlled and enhanced. A theoretical model is proposed and the concept is prototyped experimentally through an embedded system setup that can provide dynamic adaptations of a sensory system comprising a MEMS microphone placed in a closed-loop feedback system. It faithfully mimics the mosquito's active hearing response as a function of the input sound intensity. This is an adaptive acoustic sensor system concept that can be exploited by sensor and system designers within acoustics and ultrasonic engineering fields.

On the enhancement of the back-to-back two-electron-one photon ionization in molecules

NASA Astrophysics Data System (ADS)

Amusia, Miron; Drukarev, Eugene

2014-05-01

Recently, the long ago predicted quasi-free mechanism of two-electron photoionization was detected already at relatively low energy photoionization in He. It was observed that some pairs of electrons are leaving the target atom back-to-back, i.e. in opposite direction with almost the same energy. They have opposite spin directions. The cross-section of this process depends upon the probability for a pair of electrons to be close to each other before meeting the incoming photon. Such probability is greatly enhanced in molecules with covalent bonding, like H2. In this and similar molecules the electrons spend an essential part of time being between nuclei and thus screening them from each other. We demonstrate that indeed the back-to-back contribution is much bigger in H2 than in He. We analyze qualitatively some other situations that lead to relative growth of back-to-back contribution. Atoms with electrons with bigger principal quantum numbers have bigger back-to-back contributions. An external pressure applied to molecules forces electrons to be closer to each other. As a result for them the back-to-back contribution can be controllable enhanced.

Web Monitoring of EOS Front-End Ground Operations, Science Downlinks and Level 0 Processing

NASA Technical Reports Server (NTRS)

Cordier, Guy R.; Wilkinson, Chris; McLemore, Bruce

2008-01-01

This paper addresses the efforts undertaken and the technology deployed to aggregate and distribute the metadata characterizing the real-time operations associated with NASA Earth Observing Systems (EOS) high-rate front-end systems and the science data collected at multiple ground stations and forwarded to the Goddard Space Flight Center for level 0 processing. Station operators, mission project management personnel, spacecraft flight operations personnel and data end-users for various EOS missions can retrieve the information at any time from any location having access to the internet. The users are distributed and the EOS systems are distributed but the centralized metadata accessed via an external web server provide an effective global and detailed view of the enterprise-wide events as they are happening. The data-driven architecture and the implementation of applied middleware technology, open source database, open source monitoring tools, and external web server converge nicely to fulfill the various needs of the enterprise. The timeliness and content of the information provided are key to making timely and correct decisions which reduce project risk and enhance overall customer satisfaction. The authors discuss security measures employed to limit access of data to authorized users only.

Integrating RFID technique to design mobile handheld inventory management system

NASA Astrophysics Data System (ADS)

Huang, Yo-Ping; Yen, Wei; Chen, Shih-Chung

2008-04-01

An RFID-based mobile handheld inventory management system is proposed in this paper. Differing from the manual inventory management method, the proposed system works on the personal digital assistant (PDA) with an RFID reader. The system identifies electronic tags on the properties and checks the property information in the back-end database server through a ubiquitous wireless network. The system also provides a set of functions to manage the back-end inventory database and assigns different levels of access privilege according to various user categories. In the back-end database server, to prevent improper or illegal accesses, the server not only stores the inventory database and user privilege information, but also keeps track of the user activities in the server including the login and logout time and location, the records of database accessing, and every modification of the tables. Some experimental results are presented to verify the applicability of the integrated RFID-based mobile handheld inventory management system.

General-Purpose Front End for Real-Time Data Processing

NASA Technical Reports Server (NTRS)

James, Mark

2007-01-01

FRONTIER is a computer program that functions as a front end for any of a variety of other software of both the artificial intelligence (AI) and conventional data-processing types. As used here, front end signifies interface software needed for acquiring and preprocessing data and making the data available for analysis by the other software. FRONTIER is reusable in that it can be rapidly tailored to any such other software with minimum effort. Each component of FRONTIER is programmable and is executed in an embedded virtual machine. Each component can be reconfigured during execution. The virtual-machine implementation making FRONTIER independent of the type of computing hardware on which it is executed.

Effect of Stacking Layup on Spring-back Deformation of Symmetrical Flat Laminate Composites Manufactured through Autoclave Processing

NASA Astrophysics Data System (ADS)

Nasir, M. N. M.; Seman, M. A.; Mezeix, L.; Aminanda, Y.; Rivai, A.; Ali, K. M.

2017-03-01

The residual stresses that develop within fibre-reinforced laminate composites during autoclave processing lead to dimensional warpage known as spring-back deformation. A number of experiments have been conducted on flat laminate composites with unidirectional fibre orientation to examine the effects of both the intrinsic and extrinsic parameters on the warpage. This paper extends the study on to the symmetrical layup effect on spring-back for flat laminate composites. Plies stacked at various symmetrical sequences were fabricated to observe the severity of the resulting warpage. Essentially, the experimental results demonstrated that the symmetrical layups reduce the laminate stiffness in its principal direction compared to the unidirectional laminate thus, raising the spring-back warpage with the exception of the [45/-45]S layup due to its quasi-isotropic property.

Coplanar back contacts for thin silicon solar cells

NASA Technical Reports Server (NTRS)

Thornhill, J. W.; Sipperly, W. E.

1980-01-01

A process for fabricating 2 to 3 mil wraparound solar cells was formulated. Sample thin wraparound cells were fabricated using this process. The process used a reinforced perimeter construction to reduce the breakage that occurs during handling of the wafers. A retracting piston post was designed and fabricated to help minimize the breakage that occurs during the screen printing process. Two alternative methods of applying the aluminum back surface field were investigated. In addition to the standard screen printed back surface field, both spin-on and evaporated aluminum techniques were researched. Neither spin-on nor evaporated aluminum made any noticeable improvement over the screen printing technique. A fine screen mesh was chosen for the application of the aluminum paste back surface field. The optimum time and temperature for firing the aluminum turned out to be thirty seconds at 850 C. The development work on the dielectric included looking at three dielectrics for the wraparound application. Transene 1000, Thick Film Systems 1126RCB and an in house formulation 61-2-2A were all tested. Cells with pre-dielectric thickness of 3.0-0-3.5 mils using Transene 1000 as the wraparound dielectric and the procedure outlined above showed an average efficiency of 10.7 percent. Thinner cells were fabricated, but had an unacceptable yield and efficiency.

Development of a data management front-end for use with a LANDSAT-based information system

NASA Technical Reports Server (NTRS)

Turner, B. J.

1982-01-01

The development and implementation of a data management front-end system for use with a LANDSAT based information system that facilitates the processsing of both LANDSAT and ancillary data was examined. The final tasks, reported on here, involved; (1) the implementation of the VICAR image processing software system at Penn State and the development of a user-friendly front-end for this system; (2) the implementation of JPL-developed software based on VICAR, for mosaicking LANDSAT scenes; (3) the creation and storage of a mosiac of 1981 summer LANDSAT data for the entire state of Pennsylvania; (4) demonstrations of the defoliation assessment procedure for Perry and Centre Counties, and presentation of the results at the 1982 National Gypsy Moth Review Meeting, and (5) the training of Pennsylvania Bureau of Forestry personnel in the use of the defoliation analysis system.

Architecture of eukaryotic mRNA 3′-end processing machinery

PubMed Central

Hill, Chris H.; Easter, Ashley D.; Emsley, Paul; Degliesposti, Gianluca; Gordiyenko, Yuliya; Santhanam, Balaji; Wolf, Jana; Wiederhold, Katrin; Dornan, Gillian L.; Skehel, Mark; Robinson, Carol V.; Passmore, Lori A.

2018-01-01

Newly transcribed eukaryotic precursor messenger RNAs (pre-mRNAs) are processed at their 3′ ends by the ~1-megadalton multiprotein cleavage and polyadenylation factor (CPF). CPF cleaves pre-mRNAs, adds a polyadenylate tail, and triggers transcription termination, but it is unclear how its various enzymes are coordinated and assembled. Here, we show that the nuclease, polymerase, and phosphatase activities of yeast CPF are organized into three modules. Using electron cryomicroscopy, we determined a 3.5-angstrom-resolution structure of the ~200-kilodalton polymerase module. This revealed four β propellers, in an assembly markedly similar to those of other protein complexes that bind nucleic acid. Combined with in vitro reconstitution experiments, our data show that the polymerase module brings together factors required for specific and efficient polyadenylation, to help coordinate mRNA 3′-end processing. PMID:29074584

Method for growing a back surface contact on an imaging detector used in conjunction with back illumination

NASA Technical Reports Server (NTRS)

Blacksberg, Jordana (Inventor); Hoenk, Michael Eugene (Inventor); Nikzad, Shouleh (Inventor)

2010-01-01

A method is provided for growing a back surface contact on an imaging detector used in conjunction with back illumination. In operation, an imaging detector is provided. Additionally, a back surface contact (e.g. a delta-doped layer, etc.) is grown on the imaging detector utilizing a process that is performed at a temperature less than 450 degrees Celsius.

The Front-End System For MARE In Milano

NASA Astrophysics Data System (ADS)

Arnaboldi, Claudio; Pessina, Gianluigi

2009-12-01

The first phase of MARE consists of 72 μ-bolometers composed each of a crystal of AgReO4 readout by Si thermistors. The spread in the thermistor characteristics and bolometer thermal coupling leads to different energy conversion gains and optimum operating points of the detectors. Detector biasing levels and voltage gains are completely remote-adjustable by the front end system developed, the subject of this paper, achieving the same signal range at the input of the DAQ system. The front end consists of a cold buffer stage, a second pseudo differential stage followed by a gain stage, an antialiasing filter, and a battery powered detector biasing set up. The DAQ system can be used to set all necessary parameters of the electronics remotely, by writing to a μ-controller located on each board. Fiber optics are used for the serial communication between the DAQ and the front end. To suppress interference noise during normal operation, the clocked devices of the front end are maintained in sleep-mode, except during the set-up phase of the experiment. An automatic DC detector characterization procedure is used to establish the optimum operating point of every detector of the array. A very low noise level has been achieved: about 3nV/□Hz at 1 Hz and 1 nV/□Hz for the white component, high frequencies.

Comparison of Different Approach of Back Projection Method in Retrieving the Rupture Process of Large Earthquakes

NASA Astrophysics Data System (ADS)

Tan, F.; Wang, G.; Chen, C.; Ge, Z.

2016-12-01

Back-projection of teleseismic P waves [Ishii et al., 2005] has been widely used to image the rupture of earthquakes. Besides the conventional narrowband beamforming in time domain, approaches in frequency domain such as MUSIC back projection (Meng 2011) and compressive sensing (Yao et al, 2011), are proposed to improve the resolution. Each method has its advantages and disadvantages and should be properly used in different cases. Therefore, a thorough research to compare and test these methods is needed. We write a GUI program, which puts the three methods together so that people can conveniently use different methods to process the same data and compare the results. Then we use all the methods to process several earthquake data, including 2008 Wenchuan Mw7.9 earthquake and 2011 Tohoku-Oki Mw9.0 earthquake, and theoretical seismograms of both simple sources and complex ruptures. Our results show differences in efficiency, accuracy and stability among the methods. Quantitative and qualitative analysis are applied to measure their dependence on data and parameters, such as station number, station distribution, grid size, calculate window length and so on. In general, back projection makes it possible to get a good result in a very short time using less than 20 lines of high-quality data with proper station distribution, but the swimming artifact can be significant. Some ways, for instance, combining global seismic data, could help ameliorate this method. Music back projection needs relatively more data to obtain a better and more stable result, which means it needs a lot more time since its runtime accumulates obviously faster than back projection with the increase of station number. Compressive sensing deals more effectively with multiple sources in a same time window, however, costs the longest time due to repeatedly solving matrix. Resolution of all the methods is complicated and depends on many factors. An important one is the grid size, which in turn influences

Applicability of ASST-A helium refrigeration system for JLab End Station Refrigerator

NASA Astrophysics Data System (ADS)

Hasan, N.; Knudsen, P.; Ganni, V.

2017-12-01

The MØLLER experiment at Jefferson Lab (JLab) is a high power (5 kW) liquid hydrogen target scheduled to be operational in the 12 GeV-era. At present, cryogenic loads and targets at three of JLab’s four experimental halls are supported by the End Station Refrigerator (ESR) - a CTI/Helix 1.5 kW 4.5 K refrigerator. It is not capable of supporting the high power target load and a capacity upgrade of the ESR cryogenic system is essential. The ASST-A helium refrigeration system is a 4 kW 4.5 K refrigerator. It was designed and used for the Superconducting Super Collider Lab (SSCL) magnet string test and later obtained by JLab after the cancellation of that project. The modified ASST-A refrigeration system, which will be called ESR-II along with a support flow from JLab’s Central Helium Liquefier (CHL) is considered as an option for the End Station Refrigerator capacity upgrade. The applicability of this system for ESR-II under varying load conditions is investigated. The present paper outlines the findings of this process study.

40 CFR 63.491 - Batch front-end process vents-recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (b)(2): (i) For an incinerator or non-combustion control device, the percent reduction of organic HAP... the process vent stream is introduced with combustion air or is used as a secondary fuel and is not... combustion device to control halogenated batch front-end process vents or halogenated aggregate batch vent...

Measuring End-of-Life Care Processes in Nursing Homes

ERIC Educational Resources Information Center

Temkin-Greener, Helena; Zheng, Nan; Norton, Sally A.; Quill, Timothy; Ladwig, Susan; Veazie, Peter

2009-01-01

Purpose: The objectives of this study were to develop measures of end-of-life (EOL) care processes in nursing homes and to validate the instrument for measuring them. Design and Methods: A survey of directors of nursing was conducted in 608 eligible nursing homes in New York State. Responses were obtained from 313 (51.5% response rate) facilities.…

An Economic Case for End System Multicast

NASA Astrophysics Data System (ADS)

Analoui, Morteza; Rezvani, Mohammad Hossein

This paper presents a non-strategic model for the end-system multicast networks based on the concept of replica exchange economy. We believe that microeconomics is a good candidate to investigate the problem of selfishness of the end-users (peers) in order to maximize the aggregate throughput. In this solution concept, the decisions that a peer might make, does not affect the actions of the other peers at all. The proposed mechanism tunes the price of the service in such a way that general equilibrium holds.

End-To-End Simulation of Launch Vehicle Trajectories Including Stage Separation Dynamics

NASA Technical Reports Server (NTRS)

Albertson, Cindy W.; Tartabini, Paul V.; Pamadi, Bandu N.

2012-01-01

The development of methodologies, techniques, and tools for analysis and simulation of stage separation dynamics is critically needed for successful design and operation of multistage reusable launch vehicles. As a part of this activity, the Constraint Force Equation (CFE) methodology was developed and implemented in the Program to Optimize Simulated Trajectories II (POST2). The objective of this paper is to demonstrate the capability of POST2/CFE to simulate a complete end-to-end mission. The vehicle configuration selected was the Two-Stage-To-Orbit (TSTO) Langley Glide Back Booster (LGBB) bimese configuration, an in-house concept consisting of a reusable booster and an orbiter having identical outer mold lines. The proximity and isolated aerodynamic databases used for the simulation were assembled using wind-tunnel test data for this vehicle. POST2/CFE simulation results are presented for the entire mission, from lift-off, through stage separation, orbiter ascent to orbit, and booster glide back to the launch site. Additionally, POST2/CFE stage separation simulation results are compared with results from industry standard commercial software used for solving dynamics problems involving multiple bodies connected by joints.

System Enhancements for Mechanical Inspection Processes

NASA Technical Reports Server (NTRS)

Hawkins, Myers IV

2011-01-01

Quality inspection of parts is a major component to any project that requires hardware implementation. Keeping track of all of the inspection jobs is essential to having a smooth running process. By using HTML, the programming language ColdFusion, and the MySQL database, I created a web-based job management system for the 170 Mechanical Inspection Group that will replace the Microsoft Access based management system. This will improve the ways inspectors and the people awaiting inspection view and keep track of hardware as it is in the inspection process. In the end, the management system should be able to insert jobs into a queue, place jobs in and out of a bonded state, pre-release bonded jobs, and close out inspection jobs.

Advanced information processing system for advanced launch system: Avionics architecture synthesis

NASA Technical Reports Server (NTRS)

Lala, Jaynarayan H.; Harper, Richard E.; Jaskowiak, Kenneth R.; Rosch, Gene; Alger, Linda S.; Schor, Andrei L.

1991-01-01

The Advanced Information Processing System (AIPS) is a fault-tolerant distributed computer system architecture that was developed to meet the real time computational needs of advanced aerospace vehicles. One such vehicle is the Advanced Launch System (ALS) being developed jointly by NASA and the Department of Defense to launch heavy payloads into low earth orbit at one tenth the cost (per pound of payload) of the current launch vehicles. An avionics architecture that utilizes the AIPS hardware and software building blocks was synthesized for ALS. The AIPS for ALS architecture synthesis process starting with the ALS mission requirements and ending with an analysis of the candidate ALS avionics architecture is described.

Robotic end-effector for rewaterproofing shuttle tiles

NASA Astrophysics Data System (ADS)

Manouchehri, Davoud; Hansen, Joseph M.; Wu, Cheng M.; Yamamoto, Brian S.; Graham, Todd

1992-11-01

This paper summarizes work by Rockwell International's Space Systems Division's Robotics Group at Downey, California. The work is part of a NASA-led team effort to automate Space Shuttle rewaterproofing in the Orbiter Processing Facility at the Kennedy Space Center and the ferry facility at the Ames-Dryden Flight Research Facility. Rockwell's effort focuses on the rewaterproofing end-effector, whose function is to inject hazardous dimethylethyloxysilane into thousands of ceramic tiles on the underside of the orbiter after each flight. The paper has five sections. First, it presents background on the present manual process. Second, end-effector requirements are presented, including safety and interface control. Third, a design is presented for the five end-effector systems: positioning, delivery, containment, data management, and command and control. Fourth, end-effector testing and integrating to the total system are described. Lastly, future applications for this technology are discussed.

System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.

PubMed

Kang, Wenjun; Kadri, Sabah; Puranik, Rutika; Wurst, Michelle N; Patil, Sushant A; Mujacic, Ibro; Benhamed, Sonia; Niu, Nifang; Zhen, Chao Jie; Ameti, Bekim; Long, Bradley C; Galbo, Filipo; Montes, David; Iracheta, Crystal; Gamboa, Venessa L; Lopez, Daisy; Yourshaw, Michael; Lawrence, Carolyn A; Aisner, Dara L; Fitzpatrick, Carrie; McNerney, Megan E; Wang, Y Lynn; Andrade, Jorge; Volchenboum, Samuel L; Furtado, Larissa V; Ritterhouse, Lauren L; Segal, Jeremy P

2018-04-24

Next-generation sequencing (NGS) diagnostic assays increasingly are becoming the standard of care in oncology practice. As the scale of an NGS laboratory grows, management of these assays requires organizing large amounts of information, including patient data, laboratory processes, genomic data, as well as variant interpretation and reporting. Although several Laboratory Information Systems and/or Laboratory Information Management Systems are commercially available, they may not meet all of the needs of a given laboratory, in addition to being frequently cost-prohibitive. Herein, we present the System for Informatics in the Molecular Pathology Laboratory, a free and open-source Laboratory Information System/Laboratory Information Management System for academic and nonprofit molecular pathology NGS laboratories, developed at the Genomic and Molecular Pathology Division at the University of Chicago Medicine. The System for Informatics in the Molecular Pathology Laboratory was designed as a modular end-to-end information system to handle all stages of the NGS laboratory workload from test order to reporting. We describe the features of the system, its clinical validation at the Genomic and Molecular Pathology Division at the University of Chicago Medicine, and its installation and testing within a different academic center laboratory (University of Colorado), and we propose a platform for future community co-development and interlaboratory data sharing. Copyright © 2018. Published by Elsevier Inc.

Comparison of Natural Language Processing Rules-based and Machine-learning Systems to Identify Lumbar Spine Imaging Findings Related to Low Back Pain.

PubMed

Tan, W Katherine; Hassanpour, Saeed; Heagerty, Patrick J; Rundell, Sean D; Suri, Pradeep; Huhdanpaa, Hannu T; James, Kathryn; Carrell, David S; Langlotz, Curtis P; Organ, Nancy L; Meier, Eric N; Sherman, Karen J; Kallmes, David F; Luetmer, Patrick H; Griffith, Brent; Nerenz, David R; Jarvik, Jeffrey G

2018-03-28

To evaluate a natural language processing (NLP) system built with open-source tools for identification of lumbar spine imaging findings related to low back pain on magnetic resonance and x-ray radiology reports from four health systems. We used a limited data set (de-identified except for dates) sampled from lumbar spine imaging reports of a prospectively assembled cohort of adults. From N = 178,333 reports, we randomly selected N = 871 to form a reference-standard dataset, consisting of N = 413 x-ray reports and N = 458 MR reports. Using standardized criteria, four spine experts annotated the presence of 26 findings, where 71 reports were annotated by all four experts and 800 were each annotated by two experts. We calculated inter-rater agreement and finding prevalence from annotated data. We randomly split the annotated data into development (80%) and testing (20%) sets. We developed an NLP system from both rule-based and machine-learned models. We validated the system using accuracy metrics such as sensitivity, specificity, and area under the receiver operating characteristic curve (AUC). The multirater annotated dataset achieved inter-rater agreement of Cohen's kappa > 0.60 (substantial agreement) for 25 of 26 findings, with finding prevalence ranging from 3% to 89%. In the testing sample, rule-based and machine-learned predictions both had comparable average specificity (0.97 and 0.95, respectively). The machine-learned approach had a higher average sensitivity (0.94, compared to 0.83 for rules-based), and a higher overall AUC (0.98, compared to 0.90 for rules-based). Our NLP system performed well in identifying the 26 lumbar spine findings, as benchmarked by reference-standard annotation by medical experts. Machine-learned models provided substantial gains in model sensitivity with slight loss of specificity, and overall higher AUC. Copyright © 2018 The Association of University Radiologists. All rights reserved.

Polarization-insensitive techniques for optical signal processing

NASA Astrophysics Data System (ADS)

Salem, Reza

2006-12-01

This thesis investigates polarization-insensitive methods for optical signal processing. Two signal processing techniques are studied: clock recovery based on two-photon absorption in silicon and demultiplexing based on cross-phase modulation in highly nonlinear fiber. The clock recovery system is tested at an 80 Gb/s data rate for both back-to-back and transmission experiments. The demultiplexer is tested at a 160 Gb/s data rate in a back-to-back experiment. We experimentally demonstrate methods for eliminating polarization dependence in both systems. Our experimental results are confirmed by theoretical and numerical analysis.

Fac-Back-OPAC: An Open Source Interface to Your Library System

ERIC Educational Resources Information Center

Beccaria, Mike; Scott, Dan

2007-01-01

The new Fac-Back-OPAC (a faceted backup OPAC) is built on code that was originally developed by Casey Durfee in February 2007. It represents the convergence of two prominent trends in library tools: the decoupling of discovery tools from the traditional integrated library system (ILS) and the use of readily available open source components to…

Maxillary molar distalization: Pendulum and Fast-Back, comparison between two approaches for Class II malocclusion.

PubMed

Caprioglio, Alberto; Beretta, Matteo; Lanteri, Claudio

2011-01-01

To compare the dento-alveolar and skeletal effects produced by two different molar intraoral distalization appliances, Pendulum and Fast-Back, both followed by fixed appliances, in the treatment of Class II malocclusion. 41 patients for Pendulum (18 males and 23 females) and 35 for Fast-Back (14 males and 21 females) were selected, with a mean age at the start of treatment of 12.11 years in the Pendulum group and 13.3 for in the Fast-Back group. The durations of the distalization phase were 8 months in the Pendulum group and 9 months in the Fast-Back group, and the durations of the second phase of treatment with fixed appliances were 19 months in the Pendulum group and 20 months in the Fast-Back group. Lateral cephalograms were analyzed at 3 observation times: before treatment, after distalization and after comprehensive orthodontic treatment. During molar distalization the Pendulum subjects showed greater distal molar movement and less anchorage loss at both the premolars and maxillary incisors than the Fast-Back subjects. Pendulum and Fast-Back produced similar amounts of distal molar movement and overcorrection of molar relationship at the end of distalization though the Fast-Back induced a more bodily movement. Very little change occurred in the inclination of the mandibular plane at the end of the 2-phase treatment in both groups. At the end of treatment the maxillary first molars were on average 1mm more distal in the Pendulum group compared to the Fast-Back group, while the total molar correction was 3.2mm with 3.9° of distal inclination for the Pendulum and 2mm with 1.1° of mesial inclination for the Fast-Back. Both appliance were equally effective in inducing a satisfactory Class I relationship in 97.2% of the cases. The Pendulum and the Fast-Back induce similar dentoskeletal effects. The use of the two distalization devices, therefore, can be considered clinically equivalent. Copyright © 2011 Società Italiana di Ortodonzia SIDO. Published by Elsevier

End-to-end Cyberinfrastructure and Data Services for Earth System Science Education and Research: Unidata's Plans and Directions

NASA Astrophysics Data System (ADS)

Ramamurthy, M.

2005-12-01

A revolution is underway in the role played by cyberinfrastructure and data services in the conduct of research and education. We live in an era of an unprecedented data volume from diverse sources, multidisciplinary analysis and synthesis, and active, learner-centered education emphasis. For example, modern remote-sensing systems like hyperspectral satellite instruments generate terabytes of data each day. Environmental problems such as global change and water cycle transcend disciplinary as well as geographic boundaries, and their solution requires integrated earth system science approaches. Contemporary education strategies recommend adopting an Earth system science approach for teaching the geosciences, employing new pedagogical techniques such as enquiry-based learning and hands-on activities. Needless to add, today's education and research enterprise depends heavily on robust, flexible and scalable cyberinfrastructure, especially on the ready availability of quality data and appropriate tools to manipulate and integrate those data. Fortuitously, rapid advances in computing and communication technologies have also revolutionized how data, tools and services are being incorporated into the teaching and scientific enterprise. The exponential growth in the use of the Internet in education and research, largely due to the advent of the World Wide Web, is by now well documented. On the other hand, how some of the other technological and community trends that have shaped the use of cyberinfrastructure, especially data services, is less well understood. For example, the computing industry is converging on an approach called Web services that enables a standard and yet revolutionary way of building applications and methods to connect and exchange information over the Web. This new approach, based on XML - a widely accepted format for exchanging data and corresponding semantics over the Internet - enables applications, computer systems, and information processes to

An analysis of the back end of the nuclear fuel cycle with emphasis on high-level waste management, volume 1

NASA Technical Reports Server (NTRS)

1977-01-01

The programs and plans of the U.S. government for the "back end of the nuclear fuel cycle" were examined to determine if there were any significant technological or regulatory gaps and inconsistencies. Particular emphasis was placed on analysis of high-level nuclear waste management plans, since the permanent disposal of radioactive waste has emerged as a major factor in the public acceptance of nuclear power. The implications of various light water reactor fuel cycle options were examined including throwaway, stowaway, uranium recycle, and plutonium plus uranium recycle. The results of this study indicate that the U.S. program for high-level waste management has significant gaps and inconsistencies. Areas of greatest concern include: the adequacy of the scientific data base for geological disposal; programs for the the disposal of spent fuel rods; interagency coordination; and uncertainties in NRC regulatory requirements for disposal of both commercial and military high-level waste.

New Tooling System for Forming Aluminum Beverage Can End Shell

NASA Astrophysics Data System (ADS)

Yamazaki, Koetsu; Otsuka, Takayasu; Han, Jing; Hasegawa, Takashi; Shirasawa, Taketo

2011-08-01

This paper proposes a new tooling system for forming shells of aluminum beverage can ends. At first, forming process of a conversional tooling system has been simulated using three-dimensional finite element models. Simulation results have been confirmed to be consistent with those of axisymmetric models, so simulations for further study have been performed using axisymmetric models to save computational time. A comparison shows that thinning of the shell formed by the proposed tooling system has been improved about 3.6%. Influences of the tool upmost surface profiles and tool initial positions in the new tooling system have been investigated and the design optimization method based on the numerical simulations has been then applied to search optimum design points, in order to minimize thinning subjected to the constraints of the geometrical dimensions of the shell. At last, the performance of the shell subjected to internal pressure has been confirmed to meet design requirements.

The supportive process for ending intimate partner violence after pregnancy: the experience of Nicaraguan women.

PubMed

Salazar, Mariano; Högberg, Ulf; Valladares, Eliette; Ohman, Ann

2012-11-01

This grounded theory study found that Nicaraguan mothers exposed to intimate partner violence (IPV) during pregnancy eventually acted to protect their children and themselves. They experienced ending abuse as an empowerment process characterized by a cognitive change in women's attitudes toward partner abuse and the emergence of help-seeking strategies that lead to ending violence with or without ending the relationship. This process was facilitated by a supportive environment that challenged abusive behaviors as well as being asked about abuse during their last pregnancy. Although environmental changes can facilitate ending abuse, Nicaragua's public institutions must be strengthened to reach women in need.

Influence of an Optimized Thermoelectric Generator on the Back Pressure of the Subsequent Exhaust Gas System of a Vehicle

NASA Astrophysics Data System (ADS)

Kühn, Roland; Koeppen, Olaf; Kitte, Jens

2014-06-01

Numerous research projects in automotive engineering focus on the industrialization of the thermoelectric generator (TEG). The development and the implementation of thermoelectric systems into the vehicle environment are commonly supported by virtual design activities. In this paper a customized simulation architecture is presented that includes almost all vehicle parts which are influenced by the TEG (overall system simulation) but is nevertheless capable of real-time use. Moreover, an optimized planar TEG with minimum nominal power output of about 580 W and pressure loss at nominal conditions of 10 mbar, synthesized using the overall system simulation, and the overall system simulation itself are used to answer a generally neglected question: What influence does the position of a TEG have on the back pressure of the subsequent exhaust gas system of the vehicle? It is found that the influence of the TEG on the muffler is low, but the catalytic converter is strongly influenced. It is shown that the TEG can reduce the back pressure of an exhaust gas system so much that its overall back pressure is less than the back pressure of a standard exhaust gas system.

Nickel aluminide-copper backing for butt joint welding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raghavan, S.; Muszynski, M.; Chin, B.A.

1996-12-31

Single-side full penetration welding is the primary welding process in shipbuilding. This process requires the use of a backing to support the molten metal. Conventionally, copper has been used as the backing material in the shop and ceramic tiles for jobs on the field. However, copper has shown to contaminate the weld and produce adverse effects and ceramics have shown to produce porosities in the weld. A new backing with an intermetallic layer (NiAl) on the copper surface has been fabricated. The results indicate that this backing could alleviate the contamination problems and produce quality welds.

Power flow controller with a fractionally rated back-to-back converter

DOEpatents

Divan, Deepakraj M.; Kandula, Rajendra Prasad; Prasai, Anish

2016-03-08

A power flow controller with a fractionally rated back-to-back (BTB) converter is provided. The power flow controller provide dynamic control of both active and reactive power of a power system. The power flow controller inserts a voltage with controllable magnitude and phase between two AC sources at the same frequency; thereby effecting control of active and reactive power flows between the two AC sources. A transformer may be augmented with a fractionally rated bi-directional Back to Back (BTB) converter. The fractionally rated BTB converter comprises a transformer side converter (TSC), a direct-current (DC) link, and a line side converter (LSC). By controlling the switches of the BTB converter, the effective phase angle between the two AC source voltages may be regulated, and the amplitude of the voltage inserted by the power flow controller may be adjusted with respect to the AC source voltages.

Analysis Of Scoliosis By Back Shape Topography

NASA Astrophysics Data System (ADS)

Turner-Smith, Alan R.; Harris, John D.

1983-07-01

The use of surface topography for the assessment of scoliotic deformity in the clinic depends firstly on the quality of measures which reliably characterise deformity of the back, and secondly on the ease and speed with which these measures can be applied. A method of analysis of back shape measurements is presented which can be applied to any topographic measurement system. Measures presented are substantially independent of minor changes in the patient's posture in rotation and flexion from one clinic to the next, and yet sensitive enough to indicate significant improvement or degeneration of the disease. The presentation shows (1) horizontal cross-sections at ten levels up the back from sacrum to vertebra prominens, (2) angles of rotation of the surface over a small region about the spine, (3) three vertical profiles following the line of the spine, and (4) measures of maximum kyphosis and lordosis. Dependence on the operator has been reduced to a minimum. Extreme care in positioning the patient is unnecessary and those spinous processes which are easily palpable, the vertebra prominens and the two dimples over the posterior superior iliac spines are marked. Analysis proceeds entirely automatically once the basic shape data have been supplied. Applications of the technique to indirect moire topography and a television topographic measurement system are described.

Backing up and Moving forward in Fractional Understanding

ERIC Educational Resources Information Center

Barlow, Angela T.; Lischka, Alyson E.; Willingham, James C.; Hartland, Kristin S.

2017-01-01

This article describes a process called "Backing Up" which is a way to preassess student understanding of a topic and gauge student readiness to move forward in the learning process. This process of backing up begins with using responses to a word problem to identify categories of students' understandings in relation to the expectations…

Magma Plumbing System at a Young Back-Arc Spreading Center: The Marsili Volcano, Southern Tyrrhenian Sea

NASA Astrophysics Data System (ADS)

Trua, T.; Marani, M. P.; Gamberi, F.

2018-01-01

Although spreading rate is commonly taken as a proxy for decompression mantle melting at mid-ocean ridges (MORs), magmatism at back-arc spreading centers (BASCs) is further influenced by the subduction-related flux melting of the mantle. These regions consequently show a diversity of crustal structures, lava compositions, and morphologies not typically found in MORs. Here we investigate the crustal plumbing system of the small-scale, Marsili back-arc spreading center of the Southern Tyrrhenian Sea using plagioclase data from a wide spectrum of lavas (basalts to andesites) dredged from its summit and flanks. We employ petrological modeling to identify the plagioclase populations carried in the individual lavas, allocate them to plausible magmatic components present within the plumbing system, and trace the processes occurring during magma ascent to the surface. The properties of the system, such as mush porosity and abundance of the melt bodies, vary from one magma extraction zone to another along the BASC, evidencing the local variability of melt supply conditions. The plagioclase crystals document a range of relationships with the host lavas, indicating magma extraction from a composite, vertically extensive mush and melt-lens system resembling that of MORs. At the same time, however, in small BASCs, such as in the case of the Marsili Basin, crustal accretion and resulting morphology are significantly influenced by the three-dimensional setting of the basin margins. This is an important deviation from the conventional model based on the linear continuity and essentially two-dimensional framework of MORs.

System for exchanging tools and end effectors on a robot

DOEpatents

Burry, David B.; Williams, Paul M.

1991-02-19

A system and method for exchanging tools and end effectors on a robot permits exchange during a programmed task. The exchange mechanism is located off the robot, thus reducing the mass of the robot arm and permitting smaller robots to perform designated tasks. A simple spring/collet mechanism mounted on the robot is used which permits the engagement and disengagement of the tool or end effector without the need for a rotational orientation of the tool to the end effector/collet interface. As the tool changing system is not located on the robot arm no umbilical cords are located on robot.

System for exchanging tools and end effectors on a robot

DOEpatents

Burry, D.B.; Williams, P.M.

1991-02-19

A system and method for exchanging tools and end effectors on a robot permits exchange during a programmed task. The exchange mechanism is located off the robot, thus reducing the mass of the robot arm and permitting smaller robots to perform designated tasks. A simple spring/collet mechanism mounted on the robot is used which permits the engagement and disengagement of the tool or end effector without the need for a rotational orientation of the tool to the end effector/collet interface. As the tool changing system is not located on the robot arm no umbilical cords are located on robot. 12 figures.

The role of information search in seeking alternative treatment for back pain: a qualitative analysis

PubMed Central

2014-01-01

Background Health consumers have moved away from a reliance on medical practitioner advice to more independent decision processes and so their information search processes have subsequently widened. This study examined how persons with back pain searched for alternative treatment types and service providers. That is, what information do they seek and how; what sources do they use and why; and by what means do they search for it? Methods 12 persons with back pain were interviewed. The method used was convergent interviewing. This involved a series of semi-structured questions to obtain open-ended answers. The interviewer analysed the responses and refined the questions after each interview, to converge on the dominant factors influencing decisions about treatment patterns. Results Persons with back pain mainly search their memories and use word of mouth (their doctor and friends) for information about potential treatments and service providers. Their search is generally limited due to personal, provider-related and information-supply reasons. However, they did want in-depth information about the alternative treatments and providers in an attempt to establish apriori their efficacy in treating their specific back problems. They searched different sources depending on the type of information they required. Conclusions The findings differ from previous studies about the types of information health consumers require when searching for information about alternative or mainstream healthcare services. The results have identified for the first time that limited information availability was only one of three categories of reasons identified about why persons with back pain do not search for more information particularly from external non-personal sources. PMID:24725300

An 8.4-GHz dual-maser front-end system for Parkes reimplementation

NASA Technical Reports Server (NTRS)

Trowbridge, D. L.; Loreman, J. R.; Brunzie, T. J.; Quinn, R.

1990-01-01

An 8.4-GHz front-end system consisting of a feedhorn, a waveguide feed assembly, dual masers, and downconverters was reimplemented at Parkes as part of the Parkes Canberra Telemetry Array for the Voyager Neptune encounter. The front-end system was originally assembled by the European Space Agency and installed on the Parkes antenna for the Giotto project. It was also used on a time-sharing basis by the Deep Space Network as part of the Parkes Canberra Telemetry Array to enhance the data return from the Voyager Uranus encounter. At the conclusion of these projects in 1986, part of the system was then shipped to JPL on loan for reimplementation at Parkes for the Voyager Neptune encounter. New design and implementation required to make the system operable at Parkes included new microwave front-end control cabinets, closed-cycle refrigeration monitor system, noise-adding radiometer system, front-end controller assembly, X81 local oscillator multiplier, and refurbishment of the original dual 8.4-GHz traveling-wave masers and waveguide feed system. The front-end system met all requirements during the encounter and was disassembled in October 1989 and returned to JPL.

Looking back: forward looking

PubMed Central

2017-01-01

Abstract GigaScience is now 5 years old, having been launched at the 2012 Intelligent Systems for Molecular Biology conference. Anyone who has attended what is the largest computational biology conference since then has had the opportunity to join us for each birthday celebration—and receive 1 of our fun T-shirts as a party prize. Since launching, we have pushed our agenda of openness, transparency, reproducibility, and reusability. Here, we look back at our first 5 years and what we have done to forward our open science goals in scientific publishing. Our mainstay has been to create a process that allows the availability and publication of as many “research objects” as possible to create a more complete way of communicating how the research process is done. PMID:28938718

Looking back: forward looking.

PubMed

Edmunds, Scott C; Nogoy, Nicole A; Zauner, Hans; Li, Peter; Hunter, Christopher I; Zhe, Xiao Si; Goodman, Laurie

2017-09-01

GigaScience is now 5 years old, having been launched at the 2012 Intelligent Systems for Molecular Biology conference. Anyone who has attended what is the largest computational biology conference since then has had the opportunity to join us for each birthday celebration-and receive 1 of our fun T-shirts as a party prize. Since launching, we have pushed our agenda of openness, transparency, reproducibility, and reusability. Here, we look back at our first 5 years and what we have done to forward our open science goals in scientific publishing. Our mainstay has been to create a process that allows the availability and publication of as many "research objects" as possible to create a more complete way of communicating how the research process is done. © The Authors 2017. Published by Oxford University Press.

POSSIBLE ROLE OF INDOOR RADON REDUCTION SYSTEMS IN BACK-DRAFTING RESIDENTIAL COMBUSTION APPLIANCES

EPA Science Inventory

The article gives results of a computational sensitivity analysis conducted to identify conditions under which residential active soil depressurization (ASD) systems for indoor radon reduction might contribute to or create back-drafting of natural draft combustion appliances. Par...

Normative data on the n-back task for children and young adolescents

PubMed Central

Pelegrina, Santiago; Lechuga, M. Teresa; García-Madruga, Juan A.; Elosúa, M. Rosa; Macizo, Pedro; Carreiras, Manuel; Fuentes, Luis J.; Bajo, M. Teresa

2015-01-01

The n-back task is a frequently used measure of working memory (WM) in cognitive neuroscience research contexts, and it has become widely adopted in other areas over the last decade. This study aimed to obtain normative data for the n-back task from a large sample of children and adolescents. To this end, a computerized verbal n-back task with three levels of WM load (1-back, 2-back, and 3-back) was administered to 3722 Spanish school children aged 7–13 years. Results showed an overall age-related increase in performance for the different levels of difficulty. This trend was less pronounced at 1-back than at 2-back when hits were considered. Gender differences were also observed, with girls outperforming boys although taking more time to respond. The theoretical implications of these results are discussed. Normative data stratified by age and gender for the three WM load levels are provided. PMID:26500594

Normative data on the n-back task for children and young adolescents.

PubMed

Pelegrina, Santiago; Lechuga, M Teresa; García-Madruga, Juan A; Elosúa, M Rosa; Macizo, Pedro; Carreiras, Manuel; Fuentes, Luis J; Bajo, M Teresa

2015-01-01

The n-back task is a frequently used measure of working memory (WM) in cognitive neuroscience research contexts, and it has become widely adopted in other areas over the last decade. This study aimed to obtain normative data for the n-back task from a large sample of children and adolescents. To this end, a computerized verbal n-back task with three levels of WM load (1-back, 2-back, and 3-back) was administered to 3722 Spanish school children aged 7-13 years. Results showed an overall age-related increase in performance for the different levels of difficulty. This trend was less pronounced at 1-back than at 2-back when hits were considered. Gender differences were also observed, with girls outperforming boys although taking more time to respond. The theoretical implications of these results are discussed. Normative data stratified by age and gender for the three WM load levels are provided.

An in vivo study of low back pain and shock absorption in the human locomotor system.

PubMed

Voloshin, A; Wosk, J

1982-01-01

In this second of three papers, the principles of a non-invasive in vivo method to quantitatively evaluate the shock absorbing capacity of the human musculoskeletal system and the correlation of this shock absorbing capacity with low back pain (LPB) symptoms are presented. The experiments involved patients suffering from low back pain (as well as other degenerative joint diseases) and healthy patients. The obtained results reveal that low back pain correlates with the reduced capacity of the human musculoskeletal system between the femoral condyle and the forehead to attenuate incoming shock waves. Examination of the absolute values of the amplitude of the propagated waves leads to the conclusion that the human locomotor system, which possesses reduced attenuation capacity, tries to prevent overloading of the head from insufficiently attenuated shock waves. Results of the present investigation support the idea that the repetitive loading resulting from gait generates intermittent waves that propagate through the entire human musculoskeletal system from the heel up to the head. These waves are gradually attenuated along this course by the natural shock absorbers (bone and soft tissues). Contemporary methods for examination of the human musculoskeletal system may by improved by using the proposed non-invasive in vivo technique for quantitative characterization of the locomotor system's shock absorbing capacity.

Algebraic Approaches for Scalable End-to-End Monitoring and Diagnosis

NASA Astrophysics Data System (ADS)

Zhao, Yao; Chen, Yan

The rigidity of the Internet architecture led to flourish in the research of end-to-end based systems. In this chapter, we describe a linear algebra-based end-to-end monitoring and diagnosis system. We first propose a tomography-based overlay monitoring system (TOM). Given n end hosts, TOM selectively monitors a basis set of O(nlogn) paths out of all n(n - 1) end-to-end paths. Any end-to-end path can be written as a unique linear combination of paths in the basis set. Consequently, by monitoring loss rates for the paths in the basis set, TOM infers loss rates for all end-to-end paths. Furthermore, leveraging on the scalable measurements from the TOM system, we propose the Least-biased End-to-End Network Diagnosis (in short, LEND) system. We define a minimal identifiable link sequence (MILS) as a link sequence of minimal length whose properties can be uniquely identified from end-to-end measurements. LEND applies an algebraic approach to find out the MILSes and infers the properties of the MILSes efficiently. This also means LEND system achieves the finest diagnosis granularity under the least biased statistical assumptions.

The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila.

PubMed

Liu, Nan; Abe, Masashi; Sabin, Leah R; Hendriks, Gert-Jan; Naqvi, Ammar S; Yu, Zhenming; Cherry, Sara; Bonini, Nancy M

2011-11-22

MicroRNAs (miRNAs) are endogenous noncoding small RNAs with important roles in many biological pathways; their generation and activity are under precise regulation [1-3]. Emerging evidence suggests that miRNA pathways are precisely modulated with controls at the level of transcription [4-8], processing [9-11], and stability [12, 13], with miRNA deregulation linked with diseases [14] and neurodegenerative disorders [15]. In the Drosophila miRNA biogenesis pathway, long primary miRNA transcripts undergo sequential cleavage [16-18] to release the embedded miRNAs. Mature miRNAs are then loaded into Argonaute1 (Ago1) within the RNA-induced silencing complex (RISC) [19, 20]. Intriguingly, we found that Drosophila miR-34 displays multiple isoforms that differ at the 3' end, suggesting a novel biogenesis mechanism involving 3' end processing. To define the cellular factors responsible, we performed an RNA interference (RNAi) screen and identified a putative 3'→5' exoribonuclease CG9247/nibbler essential for the generation of the smaller isoforms of miR-34. Nibbler (Nbr) interacts with Ago1 and processes miR-34 within RISC. Deep sequencing analysis revealed a larger set of multi-isoform miRNAs that are controlled by nibbler. These findings suggest that Nbr-mediated 3' end processing represents a critical step in miRNA maturation that impacts miRNA diversity. Copyright © 2011 Elsevier Ltd. All rights reserved.

In-Space Propulsion Assessment Processes and Criteria for Affordable Systems

NASA Technical Reports Server (NTRS)

Zapata, Edgar; Rhodes, Russel

1999-01-01

In a world of high launch costs to Low Earth Orbit (LEO), and of costs nearly twice as high to Geosynchronous Earth Orbit (GEO), it is clear that processes and criteria are required which will surface the path to greater affordability. Further, with propulsion systems making up a major part of the systems placed into multiple orbits, or beyond, it is clear that addressing propulsion systems for in-space propulsion (ISP) is a key part to breaking the barriers to affordable systems. While multitudes of Earth to Orbit transportation system efforts focus on reduced costs, the often neglected costs and related interactions of the in-space system equally require improvements that will enable broad end-to end customer affordability.

Developing a Mobile Application "Educational Process Remote Management System" on the Android Operating System

ERIC Educational Resources Information Center

Abildinova, Gulmira M.; Alzhanov, Aitugan K.; Ospanova, Nazira N.; Taybaldieva, Zhymatay; Baigojanova, Dametken S.; Pashovkin, Nikita O.

2016-01-01

Nowadays, when there is a need to introduce various innovations into the educational process, most efforts are aimed at simplifying the learning process. To that end, electronic textbooks, testing systems and other software is being developed. Most of them are intended to run on personal computers with limited mobility. Smart education is…

In vivo characterization of the Drosophila mRNA 3′ end processing core cleavage complex

PubMed Central

Michalski, Daniel; Steiniger, Mindy

2015-01-01

A core cleavage complex (CCC) consisting of CPSF73, CPSF100, and Symplekin is required for cotranscriptional 3′ end processing of all metazoan pre-mRNAs, yet little is known about the in vivo molecular interactions within this complex. The CCC is a component of two distinct complexes, the cleavage/polyadenylation complex and the complex that processes nonpolyadenylated histone pre-mRNAs. RNAi-depletion of CCC factors in Drosophila culture cells causes reduction of CCC processing activity on histone mRNAs, resulting in read through transcription. In contrast, RNAi-depletion of factors only required for histone mRNA processing allows use of downstream cryptic polyadenylation signals to produce polyadenylated histone mRNAs. We used Dmel-2 tissue culture cells stably expressing tagged CCC components to determine that amino acids 272–1080 of Symplekin and the C-terminal approximately 200 amino acids of both CPSF73 and CPSF100 are required for efficient CCC formation in vivo. Additional experiments reveal that the C-terminal 241 amino acids of CPSF100 are sufficient for histone mRNA processing indicating that the first 524 amino acids of CPSF100 are dispensable for both CCC formation and histone mRNA 3′ end processing. CCCs containing deletions of Symplekin lacking the first 271 amino acids resulted in dramatic increased use of downstream polyadenylation sites for histone mRNA 3′ end processing similar to RNAi-depletion of histone-specific 3′ end processing factors FLASH, SLBP, and U7 snRNA. We propose a model in which CCC formation is mediated by CPSF73, CPSF100, and Symplekin C-termini, and the N-terminal region of Symplekin facilitates cotranscriptional 3′ end processing of histone mRNAs. PMID:26081560

Rear-end vision-based collision detection system for motorcyclists

NASA Astrophysics Data System (ADS)

Muzammel, Muhammad; Yusoff, Mohd Zuki; Meriaudeau, Fabrice

2017-05-01

In many countries, the motorcyclist fatality rate is much higher than that of other vehicle drivers. Among many other factors, motorcycle rear-end collisions are also contributing to these biker fatalities. To increase the safety of motorcyclists and minimize their road fatalities, this paper introduces a vision-based rear-end collision detection system. The binary road detection scheme contributes significantly to reduce the negative false detections and helps to achieve reliable results even though shadows and different lane markers are present on the road. The methodology is based on Harris corner detection and Hough transform. To validate this methodology, two types of dataset are used: (1) self-recorded datasets (obtained by placing a camera at the rear end of a motorcycle) and (2) online datasets (recorded by placing a camera at the front of a car). This method achieved 95.1% accuracy for the self-recorded dataset and gives reliable results for the rear-end vehicle detections under different road scenarios. This technique also performs better for the online car datasets. The proposed technique's high detection accuracy using a monocular vision camera coupled with its low computational complexity makes it a suitable candidate for a motorbike rear-end collision detection system.

Computerized back postural assessment in physiotherapy practice: Intra-rater and inter-rater reliability of the MIDAS system.

PubMed

McAlpine, R T; Bettany-Saltikov, J A; Warren, J G

2009-01-01

Assessment of spinal posture during physiotherapy practice is routine, yet few objective measures exist to this end. The Middlesbrough Integrated Digital Assessment System (MIDAS) is a low cost portable system able to record 3D information on posture. The purpose of this study was to assess both the intra-rater and inter-rater reliability of the MIDAS system. Twenty-five healthy subjects were recruited. A repeated measures design was used to record fifteen pre-palpated landmarks on the back of each subject. To limit the sources of variability, the principal researcher palpated the landmarks for each subject. Each of three raters took two measurements on each subject in a standardized upright posture. X (medio-lateral), Y (antero-posterior) and Z (height) landmark positions were recorded via a computer interface. Both intra-rater agreement (mean ICCs - rater 1 r=0.970, rater 2 r=0.965 and rater 3 r=0.965, p< 0.001) and inter-rater agreement (mean ICCs r=0.967, p< 0.001) was very high between repeated measures and between markers. Error values for the z-axis (height) were the lowest. The MIDAS demonstrated both high inter-rater and intra-rater reliability and provides an objective method for the assessment of posture in physiotherapy practice.

Screen-printed back-to-back electroanalytical sensors.

PubMed

Metters, Jonathan P; Randviir, Edward P; Banks, Craig E

2014-11-07

We introduce the concept of screen-printed back-to-back electroanalytical sensors where in this facile and generic approach, screen-printed electrodes are printed back-to-back with a common electrical connection to the two working electrodes with the counter and reference electrodes for each connected in the same manner as a normal "traditional" screen-printed sensor would be. This approach utilises the usually redundant back of the screen-printed sensor, converting this "dead-space" into a further electrochemical sensor which results in improvements in the analytical performance. In the use of the back-to-back design, the electrode area is consequently doubled with improvements in the analytical performance observed with the analytical sensitivity (gradient of a plot of peak height/analytical signal against concentration) doubling and the corresponding limit-of-detection being reduced. We also demonstrate that through intelligent electrode design, a quadruple in the observed analytical sensitivity can also be realised when double microband electrodes are used in the back-to-back configuration as long as they are placed sufficiently apart such that no diffusional interaction occurs. Such work is generic in nature and can be facilely applied to a plethora of screen-printed (and related) sensors utilising the commonly overlooked redundant back of the electrode providing facile improvements in the electroanalytical performance.

A front-end readout Detector Board for the OpenPET electronics system

NASA Astrophysics Data System (ADS)

Choong, W.-S.; Abu-Nimeh, F.; Moses, W. W.; Peng, Q.; Vu, C. Q.; Wu, J.-Y.

2015-08-01

We present a 16-channel front-end readout board for the OpenPET electronics system. A major task in developing a nuclear medical imaging system, such as a positron emission computed tomograph (PET) or a single-photon emission computed tomograph (SPECT), is the electronics system. While there are a wide variety of detector and camera design concepts, the relatively simple nature of the acquired data allows for a common set of electronics requirements that can be met by a flexible, scalable, and high-performance OpenPET electronics system. The analog signals from the different types of detectors used in medical imaging share similar characteristics, which allows for a common analog signal processing. The OpenPET electronics processes the analog signals with Detector Boards. Here we report on the development of a 16-channel Detector Board. Each signal is digitized by a continuously sampled analog-to-digital converter (ADC), which is processed by a field programmable gate array (FPGA) to extract pulse height information. A leading edge discriminator creates a timing edge that is ``time stamped'' by a time-to-digital converter (TDC) implemented inside the FPGA . This digital information from each channel is sent to an FPGA that services 16 analog channels, and then information from multiple channels is processed by this FPGA to perform logic for crystal lookup, DOI calculation, calibration, etc.

A front-end readout Detector Board for the OpenPET electronics system

DOE PAGES

Choong, W. -S.; Abu-Nimeh, F.; Moses, W. W.; ...

2015-08-12

Here, we present a 16-channel front-end readout board for the OpenPET electronics system. A major task in developing a nuclear medical imaging system, such as a positron emission computed tomograph (PET) or a single-photon emission computed tomograph (SPECT), is the electronics system. While there are a wide variety of detector and camera design concepts, the relatively simple nature of the acquired data allows for a common set of electronics requirements that can be met by a flexible, scalable, and high-performance OpenPET electronics system. The analog signals from the different types of detectors used in medical imaging share similar characteristics, whichmore » allows for a common analog signal processing. The OpenPET electronics processes the analog signals with Detector Boards. Here we report on the development of a 16-channel Detector Board. Each signal is digitized by a continuously sampled analog-to-digital converter (ADC), which is processed by a field programmable gate array (FPGA) to extract pulse height information. A leading edge discriminator creates a timing edge that is "time stamped" by a time-to-digital converter (TDC) implemented inside the FPGA. In conclusion, this digital information from each channel is sent to an FPGA that services 16 analog channels, and then information from multiple channels is processed by this FPGA to perform logic for crystal lookup, DOI calculation, calibration, etc.« less

The End-To-End Safety Verification Process Implemented to Ensure Safe Operations of the Columbus Research Module

NASA Astrophysics Data System (ADS)

Arndt, J.; Kreimer, J.

2010-09-01

The European Space Laboratory COLUMBUS was launched in February 2008 with NASA Space Shuttle Atlantis. Since successful docking and activation this manned laboratory forms part of the International Space Station(ISS). Depending on the objectives of the Mission Increments the on-orbit configuration of the COLUMBUS Module varies with each increment. This paper describes the end-to-end verification which has been implemented to ensure safe operations under the condition of a changing on-orbit configuration. That verification process has to cover not only the configuration changes as foreseen by the Mission Increment planning but also those configuration changes on short notice which become necessary due to near real-time requests initiated by crew or Flight Control, and changes - most challenging since unpredictable - due to on-orbit anomalies. Subject of the safety verification is on one hand the on orbit configuration itself including the hardware and software products, on the other hand the related Ground facilities needed for commanding of and communication to the on-orbit System. But also the operational products, e.g. the procedures prepared for crew and ground control in accordance to increment planning, are subject of the overall safety verification. In order to analyse the on-orbit configuration for potential hazards and to verify the implementation of the related Safety required hazard controls, a hierarchical approach is applied. The key element of the analytical safety integration of the whole COLUMBUS Payload Complement including hardware owned by International Partners is the Integrated Experiment Hazard Assessment(IEHA). The IEHA especially identifies those hazardous scenarios which could potentially arise through physical and operational interaction of experiments. A major challenge is the implementation of a Safety process which owns quite some rigidity in order to provide reliable verification of on-board Safety and which likewise provides enough

Evaluating back pain in older patients.

PubMed

Mazanec, D J

1999-02-01

Low back pain in the elderly has a much wider range of possible causes than in younger patients. In addition to nonspecific mechanical causes, malignancy presenting as back pain occurs more often in older patients. Other systemic and visceral causes of back pain such as polymyalgia rheumatica, aortic aneurysm, Paget disease, Parkinson disease, and osteoporosis with compression fracture occur almost exclusively in persons over age 50. Keys to diagnosis and management of low back pain in older patients are presented.

Can a new behaviorally oriented training process to improve lifting technique prevent occupationally related back injuries due to lifting?

PubMed

Lavender, Steven A; Lorenz, Eric P; Andersson, Gunnar B J

2007-02-15

A prospective randomized control trial. To determine the degree to which a new behavior-based lift training program (LiftTrainer; Ascension Technology, Burlington, VT) could reduce the incidence of low back disorder in distribution center jobs that require repetitive lifting. Most studies show programs aimed at training lifting techniques to be ineffective in preventing low back disorders, which may be due to their conceptual rather than behavioral learning approach. A total of 2144 employees in 19 distribution centers were randomized into either the LiftTrainer program or a video control group. In the LiftTrainer program, participants were individually trained in up to 5, 30-minute sessions while instrumented with motion capture sensors to quantify the L5/S1 moments. Twelve months following the initial training, injury data were obtained from company records. Survival analyses (Kaplan-Meier) indicated that there was no difference in injury rates between the 2 training groups. Likewise, there was no difference in the turnover rates. However, those with a low (<30 Nm) average twisting moment at the end of the first session experienced a significantly (P < 0.005) lower rate of low back disorder than controls. While overall the LiftTrainer program was not effective, those with twisting moments below 30 Nm reported fewer injuries, suggesting a shift in focus for "safe" lifting programs.

EUVL back-insertion layout optimization

NASA Astrophysics Data System (ADS)

Civay, D.; Laffosse, E.; Chesneau, A.

2018-03-01

Extreme ultraviolet lithography (EUVL) is targeted for front-up insertion at advanced technology nodes but will be evaluated for back insertion at more mature nodes. EUVL can put two or more mask levels back on one mask, depending upon what level(s) in the process insertion occurs. In this paper, layout optimization methods are discussed that can be implemented when EUVL back insertion is implemented. The layout optimizations can be focused on improving yield, reliability or density, depending upon the design needs. The proposed methodology modifies the original two or more colored layers and generates an optimized single color EUVL layout design.

Applying Trustworthy Computing to End-to-End Electronic Voting

ERIC Educational Resources Information Center

Fink, Russell A.

2010-01-01

"End-to-End (E2E)" voting systems provide cryptographic proof that the voter's intention is captured, cast, and tallied correctly. While E2E systems guarantee integrity independent of software, most E2E systems rely on software to provide confidentiality, availability, authentication, and access control; thus, end-to-end integrity is not…

Parallel processing spacecraft communication system

NASA Technical Reports Server (NTRS)

Bolotin, Gary S. (Inventor); Donaldson, James A. (Inventor); Luong, Huy H. (Inventor); Wood, Steven H. (Inventor)

1998-01-01

An uplink controlling assembly speeds data processing using a special parallel codeblock technique. A correct start sequence initiates processing of a frame. Two possible start sequences can be used; and the one which is used determines whether data polarity is inverted or non-inverted. Processing continues until uncorrectable errors are found. The frame ends by intentionally sending a block with an uncorrectable error. Each of the codeblocks in the frame has a channel ID. Each channel ID can be separately processed in parallel. This obviates the problem of waiting for error correction processing. If that channel number is zero, however, it indicates that the frame of data represents a critical command only. That data is handled in a special way, independent of the software. Otherwise, the processed data further handled using special double buffering techniques to avoid problems from overrun. When overrun does occur, the system takes action to lose only the oldest data.

Implications of Artificial Intelligence for End User Use of Online Systems.

ERIC Educational Resources Information Center

Smith, Linda C.

1980-01-01

Reviewed are several studies which demonstrate how artificial intelligence techniques can be applied in the design of end user-oriented interfaces (which would eliminate the need for an intermediary) to existing online systems, as well as in the development of future generations of online systems intended for the end user. (Author/SW)

A macrosonic system for industrial processing

PubMed

Gallego-Juarez; Rodriguez-Corral; Riera-Franco de Sarabia E; Campos-Pozuelo; Vazquez-Martinez; Acosta-Aparicio

2000-03-01

The development of high-power applications of sonic and ultrasonic energy in industrial processing requires a great variety of practical systems with characteristics which are dependent on the effect to be exploited. Nevertheless, the majority of systems are basically constituted of a treatment chamber and one or several transducers coupled to it. Therefore, the feasibility of the application mainly depends on the efficiency of the transducer-chamber system. This paper deals with a macrosonic system which is essentially constituted of a high-power transducer with a double stepped-plate radiator coupled to a chamber of square section. The radiator, which has a rectangular shape, is placed on one face of the chamber in order to drive the inside fluid volume. The stepped profile of the radiator allows a piston-like radiation to be obtained. The radiation from the back face of the radiator is also applied to the chamber by using adequate reflectors. Transducer-chamber systems for sonic and ultrasonic frequencies have been developed with power capacities up to about 5 kW for the treatment of fluid volumes of several cubic meters. The characteristics of these systems are presented in this paper.

Transfer after Dual n-Back Training Depends on Striatal Activation Change.

PubMed

Salminen, Tiina; Kühn, Simone; Frensch, Peter A; Schubert, Torsten

2016-09-28

The dual n-back working memory (WM) training paradigm (comprising auditory and visual stimuli) has gained much attention since studies have shown widespread transfer effects. By including a multimodal dual-task component, the task is demanding to the human cognitive system. We investigated whether dual n-back training improves general cognitive resources or a task-specific WM updating process in participants. We expected: (1) widespread transfer effects and the recruitment of a common neuronal network by the training and the transfer tasks and (2) narrower transfer results and that a common activation network alone would not produce transfer, but instead an activation focus on the striatum, which is associated with WM updating processes. The training group showed transfer to an untrained dual-modality WM updating task, but not to single-task versions of the training or the transfer task. They also showed diminished neuronal overlap between the training and the transfer task from pretest to posttest and an increase in striatal activation in both tasks. Furthermore, we found an association between the striatal activation increase and behavioral improvement. The control groups showed no transfer and no change in the amount of activation overlap or in striatal activation from pretest to posttest. We conclude that, instead of improving general cognitive resources (which would have required a transfer effect to all transfer tasks and that a frontal activation overlap between the tasks produced transfer), dual n-back training improved a task-specific process: WM updating of stimuli from two modalities. The current study allows for a better understanding of the cognitive and neural effects of working memory (WM) training and transfer. It shows that dual n-back training mainly improves specific processes of WM updating, and this improvement leads to narrow transfer effects to tasks involving the same processes. On a neuronal level this is accompanied by increased neural

Potential of Laboratory Execution Systems (LESs) to Simplify the Application of Business Process Management Systems (BPMSs) in Laboratory Automation.

PubMed

Neubert, Sebastian; Göde, Bernd; Gu, Xiangyu; Stoll, Norbert; Thurow, Kerstin

2017-04-01

Modern business process management (BPM) is increasingly interesting for laboratory automation. End-to-end workflow automation and improved top-level systems integration for information technology (IT) and automation systems are especially prominent objectives. With the ISO Standard Business Process Model and Notation (BPMN) 2.X, a system-independent and interdisciplinary accepted graphical process control notation is provided, allowing process analysis, while also being executable. The transfer of BPM solutions to structured laboratory automation places novel demands, for example, concerning the real-time-critical process and systems integration. The article discusses the potential of laboratory execution systems (LESs) for an easier implementation of the business process management system (BPMS) in hierarchical laboratory automation. In particular, complex application scenarios, including long process chains based on, for example, several distributed automation islands and mobile laboratory robots for a material transport, are difficult to handle in BPMSs. The presented approach deals with the displacement of workflow control tasks into life science specialized LESs, the reduction of numerous different interfaces between BPMSs and subsystems, and the simplification of complex process modelings. Thus, the integration effort for complex laboratory workflows can be significantly reduced for strictly structured automation solutions. An example application, consisting of a mixture of manual and automated subprocesses, is demonstrated by the presented BPMS-LES approach.

A common type system for clinical natural language processing.

PubMed

Wu, Stephen T; Kaggal, Vinod C; Dligach, Dmitriy; Masanz, James J; Chen, Pei; Becker, Lee; Chapman, Wendy W; Savova, Guergana K; Liu, Hongfang; Chute, Christopher G

2013-01-03

One challenge in reusing clinical data stored in electronic medical records is that these data are heterogenous. Clinical Natural Language Processing (NLP) plays an important role in transforming information in clinical text to a standard representation that is comparable and interoperable. Information may be processed and shared when a type system specifies the allowable data structures. Therefore, we aim to define a common type system for clinical NLP that enables interoperability between structured and unstructured data generated in different clinical settings. We describe a common type system for clinical NLP that has an end target of deep semantics based on Clinical Element Models (CEMs), thus interoperating with structured data and accommodating diverse NLP approaches. The type system has been implemented in UIMA (Unstructured Information Management Architecture) and is fully functional in a popular open-source clinical NLP system, cTAKES (clinical Text Analysis and Knowledge Extraction System) versions 2.0 and later. We have created a type system that targets deep semantics, thereby allowing for NLP systems to encapsulate knowledge from text and share it alongside heterogenous clinical data sources. Rather than surface semantics that are typically the end product of NLP algorithms, CEM-based semantics explicitly build in deep clinical semantics as the point of interoperability with more structured data types.

Tracer techniques for urine volume determination and urine collection and sampling back-up system

NASA Technical Reports Server (NTRS)

Ramirez, R. V.

1971-01-01

The feasibility, functionality, and overall accuracy of the use of lithium were investigated as a chemical tracer in urine for providing a means of indirect determination of total urine volume by the atomic absorption spectrophotometry method. Experiments were conducted to investigate the parameters of instrumentation, tracer concentration, mixing times, and methods for incorporating the tracer material in the urine collection bag, and to refine and optimize the urine tracer technique to comply with the Skylab scheme and operational parameters of + or - 2% of volume error and + or - 1% accuracy of amount of tracer added to each container. In addition, a back-up method for urine collection and sampling system was developed and evaluated. This back-up method incorporates the tracer technique for volume determination in event of failure of the primary urine collection and preservation system. One chemical preservative was selected and evaluated as a contingency chemical preservative for the storage of urine in event of failure of the urine cooling system.

Estimating the executive demands of a one-back choice reaction time task by means of the selective interference paradigm.

PubMed

Szmalec, Arnaud; Vandierendonck, André

2007-08-01

The present study proposes a new executive task, the one-back choice reaction time (RT) task, and implements the selective interference paradigm to estimate the executive demands of the processing components involved in this task. Based on the similarities between a one-back choice RT task and the n-back updating task, it was hypothesized that one-back delaying of a choice reaction involves executive control. In three experiments, framed within Baddeley's (1986) working-memory model, a one-back choice RT task, a choice RT task, articulatory suppression, and matrix tapping were performed concurrently with primary tasks involving verbal, visuospatial, and executive processing. The results demonstrate that one-back delaying of a choice reaction interferes with tasks requiring executive control, while the potential interference at the level of the verbal or visuospatial working memory slave systems remains minimal.

Bringing Knowledge Back In: Perspectives from Liberal Education

ERIC Educational Resources Information Center

Deng, Zongyi

2018-01-01

From the vantage point of liberal education, this article attempts to contribute to the conversation initiated by Michael Young and his colleagues on 'bringing knowledge back' into the current global discourse on curriculum policy and practice. The contribution is made through revisiting the knowledge-its-own-end thesis associated with Newman and…

Development of the Subaru-Mitaka-Okayama-Kiso Archive System

NASA Astrophysics Data System (ADS)

Baba, Hajime; Yasuda, Naoki; Ichikawa, Shin-Ichi; Yagi, Masafumi; Iwamoto, Nobuyuki; Takata, Tadafumi; Horaguchi, Toshihiro; Taga, Masatoshi; Watanabe, Masaru; Ozawa, Tomohiko; Hamabe, Masaru

We have developed the Subaru-Mitaka-Okayama-Kiso-Archive (SMOKA) public science archive system which provides access to the data of the Subaru Telescope, the 188 cm telescope at Okayama Astrophysical Observatory, and the 105 cm Schmidt telescope at Kiso Observatory/University of Tokyo. SMOKA is the successor of the MOKA3 system. The user can browse the Quick-Look Images, Header Information (HDI) and the ASCII Table Extension (ATE) of each frame from the search result table. A request for data can be submitted in a simple manner. The system is developed with Java Servlet for the back-end, and Java Server Pages (JSP) for content display. The advantage of JSP's is the separation of the front-end presentation from the middle- and back-end tiers which led to an efficient development of the system. The SMOKA homepage is available at SMOKA

School children's backpacks, back pain and back pathologies.

PubMed

Rodríguez-Oviedo, Paloma; Ruano-Ravina, Alberto; Pérez-Ríos, Mónica; García, Francisco Blanco; Gómez-Fernández, Dorotea; Fernández-Alonso, Anselmo; Carreira-Núñez, Isabel; García-Pacios, Pilar; Turiso, Javier

2012-08-01

To investigate whether backpack weight is associated with back pain and back pathology in school children. Cross-sectional study. Schools in Northern Galicia, Spain. All children aged 12-17. Backpack weight along with body mass index, age and gender. Back pain and back pathology. 1403 school children were analysed. Of these, 61.4% had backpacks exceeding 10% of their body weight. Those carrying the heaviest backpacks had a 50% higher risk of back pain (OR 1.50 CI 95% 1.06 to 2.12) and a 42% higher risk of back pathology, although this last result was not statistically significant (OR 1.42 CI 95% 0.86 to 2.32). Girls presented a higher risk of back pain compared with boys. Carrying backpacks increases the risk of back pain and possibly the risk of back pathology. The prevalence of school children carrying heavy backpacks is extremely high. Preventive and educational activities should be implemented in this age group.

Chiropractic Integrated Care Pathway for Low Back Pain in Veterans: Results of a Delphi Consensus Process.

PubMed

Lisi, Anthony J; Salsbury, Stacie A; Hawk, Cheryl; Vining, Robert D; Wallace, Robert B; Branson, Richard; Long, Cynthia R; Burgo-Black, A Lucille; Goertz, Christine M

2018-02-01

The purpose of this study was to develop an integrated care pathway for doctors of chiropractic, primary care providers, and mental health professionals who manage veterans with low back pain, with or without mental health comorbidity, within Department of Veterans Affairs health care facilities. The research method used was a consensus process. A multidisciplinary investigative team reviewed clinical guidelines and Veterans Affairs pain and mental health initiatives to develop seed statements and care algorithms to guide chiropractic management and collaborative care of veterans with low back pain. A 5-member advisory committee approved initial recommendations. Veterans Affairs-based panelists (n = 58) evaluated the pathway via e-mail using a modified RAND/UCLA methodology. Consensus was defined as agreement by 80% of panelists. The modified Delphi process was conducted in July to December 2016. Most (93%) seed statements achieved consensus during the first round, with all statements reaching consensus after 2 rounds. The final care pathway addressed the topics of informed consent, clinical evaluation including history and examination, screening for red flags, documentation, diagnostic imaging, patient-reported outcomes, adverse event reporting, chiropractic treatment frequency and duration standards, tailored approaches to chiropractic care in veteran populations, and clinical presentation of common mental health conditions. Care algorithms outlined chiropractic case management and interprofessional collaboration and referrals between doctors of chiropractic and primary care and mental health providers. This study offers an integrative care pathway that includes chiropractic care for veterans with low back pain. Copyright © 2018. Published by Elsevier Inc.

Balancing: a basic process in end-of-life cancer care.

PubMed

Thulesius, Hans; Håkansson, Anders; Petersson, Kerstin

2003-12-01

In this grounded theory study, the authors interviewed caregivers and patients in end-of-life cancer care and found Balancing to be a fundamental process explaining the problem-solving strategies of most participants and offering a comprehensive perspective on both health care in general and end-of-life cancer care in particular. Balancing stages were Weighing--sensing needs and wishes signaled by patients, gauging them against caregiver resources in diagnosing and care planning; Shifting--breaking bad news, changing care places, and treatments; and Compensating--controlling symptoms, educating and team-working, prioritizing and "stretching" time, innovating care methods, improvising, and maintaining the homeostasis of hope. The Balancing outcome is characterized by Compromising, or "Walking a fine line," at best an optimized situation, at worst a deceit.

An end to end secure CBIR over encrypted medical database.

PubMed

Bellafqira, Reda; Coatrieux, Gouenou; Bouslimi, Dalel; Quellec, Gwenole

2016-08-01

In this paper, we propose a new secure content based image retrieval (SCBIR) system adapted to the cloud framework. This solution allows a physician to retrieve images of similar content within an outsourced and encrypted image database, without decrypting them. Contrarily to actual CBIR approaches in the encrypted domain, the originality of the proposed scheme stands on the fact that the features extracted from the encrypted images are themselves encrypted. This is achieved by means of homomorphic encryption and two non-colluding servers, we however both consider as honest but curious. In that way an end to end secure CBIR process is ensured. Experimental results carried out on a diabetic retinopathy database encrypted with the Paillier cryptosystem indicate that our SCBIR achieves retrieval performance as good as if images were processed in their non-encrypted form.

Non-Contact Conductivity Measurement for Automated Sample Processing Systems

NASA Technical Reports Server (NTRS)

Beegle, Luther W.; Kirby, James P.

2012-01-01

A new method has been developed for monitoring and control of automated sample processing and preparation especially focusing on desalting of samples before analytical analysis (described in more detail in Automated Desalting Apparatus, (NPO-45428), NASA Tech Briefs, Vol. 34, No. 8 (August 2010), page 44). The use of non-contact conductivity probes, one at the inlet and one at the outlet of the solid phase sample preparation media, allows monitoring of the process, and acts as a trigger for the start of the next step in the sequence (see figure). At each step of the muti-step process, the system is flushed with low-conductivity water, which sets the system back to an overall low-conductivity state. This measurement then triggers the next stage of sample processing protocols, and greatly minimizes use of consumables. In the case of amino acid sample preparation for desalting, the conductivity measurement will define three key conditions for the sample preparation process. First, when the system is neutralized (low conductivity, by washing with excess de-ionized water); second, when the system is acidified, by washing with a strong acid (high conductivity); and third, when the system is at a basic condition of high pH (high conductivity). Taken together, this non-contact conductivity measurement for monitoring sample preparation will not only facilitate automation of the sample preparation and processing, but will also act as a way to optimize the operational time and use of consumables

Unmanned Aircraft Systems Detect and Avoid System: End-to-End Verification and Validation Simulation Study of Minimum Operations Performance Standards for Integrating Unmanned Aircraft into the National Airspace System

NASA Technical Reports Server (NTRS)

Ghatas, Rania W.; Jack, Devin P.; Tsakpinis, Dimitrios; Sturdy, James L.; Vincent, Michael J.; Hoffler, Keith D.; Myer, Robert R.; DeHaven, Anna M.

2017-01-01

As Unmanned Aircraft Systems (UAS) make their way to mainstream aviation operations within the National Airspace System (NAS), research efforts are underway to develop a safe and effective environment for their integration into the NAS. Detect and Avoid (DAA) systems are required to account for the lack of "eyes in the sky" due to having no human on-board the aircraft. The technique, results, and lessons learned from a detailed End-to-End Verification and Validation (E2-V2) simulation study of a DAA system representative of RTCA SC-228's proposed Phase I DAA Minimum Operational Performance Standards (MOPS), based on specific test vectors and encounter cases, will be presented in this paper.

The market of electrical and electronic equipment waste in Portugal: Analysis of take-back consumers' decisions.

PubMed

Botelho, Anabela; Ferreira Dias, Marta; Ferreira, Carla; Pinto, Lígia M Costa

2016-10-01

This paper aims to ascertain the efficacy and acceptability of five incentive schemes for the take-back of waste electrical and electronic equipment in Portugal, focusing in consumers' perspectives. It assesses users' perception of these items, evaluating the motivations and interests they have concerning the market of waste electrical and electronic equipment. Results indicate, on one hand, a lack of awareness by consumers about the process of take-back of their equipment. On the other hand, results show that information conditions and socio-demographic factors affect consumers' motivations for returning the electrical and electronic equipment at the end of life. In this context, it can be concluded that, in Portugal, the market for the recovery of waste electrical and electronic equipment is still in its infancy. © The Author(s) 2016.

Cold-end Subsystem Testing for the Fission Power System Technology Demonstration Unit

NASA Technical Reports Server (NTRS)

Briggs, Maxwell; Gibson, Marc; Ellis, David; Sanzi, James

2013-01-01

The Fission Power System (FPS) Technology Demonstration Unit (TDU) consists of a pumped sodium-potassium (NaK) loop that provides heat to a Stirling Power Conversion Unit (PCU), which converts some of that heat into electricity and rejects the waste heat to a pumped water loop. Each of the TDU subsystems is being tested independently prior to full system testing at the NASA Glenn Research Center. The pumped NaK loop is being tested at NASA Marshall Space Flight Center; the Stirling PCU and electrical controller are being tested by Sunpower Inc.; and the pumped water loop is being tested at Glenn. This paper describes cold-end subsystem setup and testing at Glenn. The TDU cold end has been assembled in Vacuum Facility 6 (VF 6) at Glenn, the same chamber that will be used for TDU testing. Cold-end testing in VF 6 will demonstrate functionality; validated cold-end fill, drain, and emergency backup systems; and generated pump performance and system pressure drop data used to validate models. In addition, a low-cost proof-of concept radiator has been built and tested at Glenn, validating the design and demonstrating the feasibility of using low-cost metal radiators as an alternative to high-cost composite radiators in an end-to-end TDU test.

QoS support for end users of I/O-intensive applications using shared storage systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, Marion Kei; Zhang, Xuechen; Jiang, Song

2011-01-19

I/O-intensive applications are becoming increasingly common on today's high-performance computing systems. While performance of compute-bound applications can be effectively guaranteed with techniques such as space sharing or QoS-aware process scheduling, it remains a challenge to meet QoS requirements for end users of I/O-intensive applications using shared storage systems because it is difficult to differentiate I/O services for different applications with individual quality requirements. Furthermore, it is difficult for end users to accurately specify performance goals to the storage system using I/O-related metrics such as request latency or throughput. As access patterns, request rates, and the system workload change in time,more » a fixed I/O performance goal, such as bounds on throughput or latency, can be expensive to achieve and may not lead to a meaningful performance guarantees such as bounded program execution time. We propose a scheme supporting end-users QoS goals, specified in terms of program execution time, in shared storage environments. We automatically translate the users performance goals into instantaneous I/O throughput bounds using a machine learning technique, and use dynamically determined service time windows to efficiently meet the throughput bounds. We have implemented this scheme in the PVFS2 parallel file system and have conducted an extensive evaluation. Our results show that this scheme can satisfy realistic end-user QoS requirements by making highly efficient use of the I/O resources. The scheme seeks to balance programs attainment of QoS requirements, and saves as much of the remaining I/O capacity as possible for best-effort programs.« less

Light vehicle forward-looking, rear-end collision warning system performance guidelines

DOT National Transportation Integrated Search

1998-05-01

This document presents performance guidelines for forward-looking, rear-end collision warning systems (abbreviated FCW) for improving vehicular safety by preventing or mitigating vehicular rear-end collisions through driver notification or warning. T...

Working with Pedagogical Agents: Understanding the "Back End" of an Intelligent Tutoring System

ERIC Educational Resources Information Center

Wolfe, Christopher; Widmer, Colin L.; Weil, Audrey M.; Cedillos-Whynott, Elizabeth M.

2015-01-01

Students in an undergraduate psychology course on Learning and Cognition used SKO (formerly AutoTutor Lite), an Intelligent Tutoring System, to create interactive lessons in which a pedagogic agent (animated avatar) engages users in a tutorial dialogue. After briefly describing the technology and underlying psychological theory, data from an…

Back-Projection Imaging of extended, diffuse seismic sources in volcanic and hydrothermal systems

NASA Astrophysics Data System (ADS)

Kelly, C. L.; Lawrence, J. F.; Beroza, G. C.

2017-12-01

Volcanic and hydrothermal systems exhibit a wide range of seismicity that is directly linked to fluid and volatile activity in the subsurface and that can be indicative of imminent hazardous activity. Seismograms recorded near volcanic and hydrothermal systems typically contain "noisy" records, but in fact, these complex signals are generated by many overlapping low-magnitude displacements and pressure changes at depth. Unfortunately, excluding times of high-magnitude eruptive activity that typically occur infrequently relative to the length of a system's entire eruption cycle, these signals often have very low signal-to-noise ratios and are difficult to identify and study using established seismic analysis techniques (i.e. phase-picking, template matching). Arrays of short-period and broadband seismic sensors are proven tools for monitoring short- and long-term changes in volcanic and hydrothermal systems. Time-reversal techniques (i.e. back-projection) that are improved by additional seismic observations have been successfully applied to locating volcano-seismic sources recorded by dense sensor arrays. We present results from a new computationally efficient back-projection method that allows us to image the evolution of extended, diffuse sources of volcanic and hydrothermal seismicity. We correlate short time-window seismograms from receiver-pairs to find coherent signals and propagate them back in time to potential source locations in a 3D subsurface model. The strength of coherent seismic signal associated with any potential source-receiver-receiver geometry is equal to the correlation of the short time-windows of seismic records at appropriate time lags as determined by the velocity structure and ray paths. We stack (sum) all short time-window correlations from all receiver-pairs to determine the cumulative coherence of signals at each potential source location. Through stacking, coherent signals from extended and/or repeating sources of short-period energy

Efficient heart beat detection using embedded system electronics

NASA Astrophysics Data System (ADS)

Ramasamy, Mouli; Oh, Sechang; Varadan, Vijay K.

2014-04-01

The present day bio-technical field concentrates on developing various types of innovative ambulatory and wearable devices to monitor several bio-physical, physio-pathological, bio-electrical and bio-potential factors to assess a human body's health condition without intruding quotidian activities. One of the most important aspects of this evolving technology is monitoring heart beat rate and electrocardiogram (ECG) from which many other subsidiary results can be derived. Conventionally, the devices and systems consumes a lot of power since the acquired signals are always processed on the receiver end. Because of this back end processing, the unprocessed raw data is transmitted resulting in usage of more power, memory and processing time. This paper proposes an innovative technique where the acquired signals are processed by a microcontroller in the front end of the module and just the processed signal is then transmitted wirelessly to the display unit. Therefore, power consumption is considerably reduced and clearer data analysis is performed within the module. This also avoids the need for the user to be educated about usage of the device and signal/system analysis, since only the number of heart beats will displayed at the user end. Additionally, the proposed concept also eradicates the other disadvantages like obtrusiveness, high power consumption and size. To demonstrate the above said factors, a commercial controller board was used to extend the monitoring method by using the saved ECG data from a computer.

GPS Satellite Orbit Prediction at User End for Real-Time PPP System.

PubMed

Yang, Hongzhou; Gao, Yang

2017-08-30

This paper proposed the high-precision satellite orbit prediction process at the user end for the real-time precise point positioning (PPP) system. Firstly, the structure of a new real-time PPP system will be briefly introduced in the paper. Then, the generation of satellite initial parameters (IP) at the sever end will be discussed, which includes the satellite position, velocity, and the solar radiation pressure (SRP) parameters for each satellite. After that, the method for orbit prediction at the user end, with dynamic models including the Earth's gravitational force, lunar gravitational force, solar gravitational force, and the SRP, are presented. For numerical integration, both the single-step Runge-Kutta and multi-step Adams-Bashforth-Moulton integrator methods are implemented. Then, the comparison between the predicted orbit and the international global navigation satellite system (GNSS) service (IGS) final products are carried out. The results show that the prediction accuracy can be maintained for several hours, and the average prediction error of the 31 satellites are 0.031, 0.032, and 0.033 m for the radial, along-track and cross-track directions over 12 h, respectively. Finally, the PPP in both static and kinematic modes are carried out to verify the accuracy of the predicted satellite orbit. The average root mean square error (RMSE) for the static PPP of the 32 globally distributed IGS stations are 0.012, 0.015, and 0.021 m for the north, east, and vertical directions, respectively; while the RMSE of the kinematic PPP with the predicted orbit are 0.031, 0.069, and 0.167 m in the north, east and vertical directions, respectively.

GPS Satellite Orbit Prediction at User End for Real-Time PPP System

PubMed Central

Yang, Hongzhou; Gao, Yang

2017-01-01

This paper proposed the high-precision satellite orbit prediction process at the user end for the real-time precise point positioning (PPP) system. Firstly, the structure of a new real-time PPP system will be briefly introduced in the paper. Then, the generation of satellite initial parameters (IP) at the sever end will be discussed, which includes the satellite position, velocity, and the solar radiation pressure (SRP) parameters for each satellite. After that, the method for orbit prediction at the user end, with dynamic models including the Earth’s gravitational force, lunar gravitational force, solar gravitational force, and the SRP, are presented. For numerical integration, both the single-step Runge–Kutta and multi-step Adams–Bashforth–Moulton integrator methods are implemented. Then, the comparison between the predicted orbit and the international global navigation satellite system (GNSS) service (IGS) final products are carried out. The results show that the prediction accuracy can be maintained for several hours, and the average prediction error of the 31 satellites are 0.031, 0.032, and 0.033 m for the radial, along-track and cross-track directions over 12 h, respectively. Finally, the PPP in both static and kinematic modes are carried out to verify the accuracy of the predicted satellite orbit. The average root mean square error (RMSE) for the static PPP of the 32 globally distributed IGS stations are 0.012, 0.015, and 0.021 m for the north, east, and vertical directions, respectively; while the RMSE of the kinematic PPP with the predicted orbit are 0.031, 0.069, and 0.167 m in the north, east and vertical directions, respectively. PMID:28867771

A computer-based time study system for timber harvesting operations

Treesearch

Jingxin Wang; Joe McNeel; John Baumgras

2003-01-01

A computer-based time study system was developed for timber harvesting operations. Object-oriented techniques were used to model and design the system. The front-end of the time study system resides on the MS Windows CE and the back-end is supported by MS Access. The system consists of three major components: a handheld system, data transfer interface, and data storage...

A next generation processing system for edging and trimming

Treesearch

A. Lynn Abbott; Daniel L. Schmoldt; Philip A. Araman

2000-01-01

This paper describes a prototype scanning system that is being developed for the processing of rough hardwood lumber. The overall goal of the system is to automate the selection of cutting positions for the edges and ends of rough, green lumber. Such edge and trim cuts are typically performed at sawmills in an effort to increase board value prior to sale, and this...

An ultra low-power front-end IC for wearable health monitoring system.

PubMed

Yu-Pin Hsu; Zemin Liu; Hella, Mona M

2016-08-01

This paper presents a low-power front-end IC for wearable health monitoring systems. The IC, designed in a standard 0.13μm CMOS technology, fully integrates a low-noise analog front-end (AFE) to process the weak bio-signals, followed by an analog-to-digital converter (ADC) to digitize the extracted signals. An AC-coupled driving buffer, that interfaces between the AFE and the ADC is introduced to scale down the power supply of the ADC. The power consumption decreases by 50% compared to the case without power supply scaling. The AFE passes signals from 0.5Hz to 280Hz and from 0.7Hz to 160Hz with a simulated input referred noise of 1.6μVrms and achieves a maximum gain of 35dB/41dB respectively, with a noise-efficiency factor (NEF) of the AFE is 1. The 8-bit ADC achieves a simulated 7.96-bit resolution at 10KS/s sampling rate under 0.5V supply voltage. The overall system consumes only 0.86μW at dual supply voltages of 1V (AFE) and 0.5 V (ADC).

The Evolutionarily Conserved Protein LAS1 Is Required for Pre-rRNA Processing at Both Ends of ITS2

PubMed Central

Schillewaert, Stéphanie; Wacheul, Ludivine; Lhomme, Frédéric

2012-01-01

Ribosome synthesis entails the formation of mature rRNAs from long precursor molecules, following a complex pre-rRNA processing pathway. Why the generation of mature rRNA ends is so complicated is unclear. Nor is it understood how pre-rRNA processing is coordinated at distant sites on pre-rRNA molecules. Here we characterized, in budding yeast and human cells, the evolutionarily conserved protein Las1. We found that, in both species, Las1 is required to process ITS2, which separates the 5.8S and 25S/28S rRNAs. In yeast, Las1 is required for pre-rRNA processing at both ends of ITS2. It is required for Rrp6-dependent formation of the 5.8S rRNA 3′ end and for Rat1-dependent formation of the 25S rRNA 5′ end. We further show that the Rat1-Rai1 5′-3′ exoribonuclease (exoRNase) complex functionally connects processing at both ends of the 5.8S rRNA. We suggest that pre-rRNA processing is coordinated at both ends of 5.8S rRNA and both ends of ITS2, which are brought together by pre-rRNA folding, by an RNA processing complex. Consistently, we note the conspicuous presence of ∼7- or 8-nucleotide extensions on both ends of 5.8S rRNA precursors and at the 5′ end of pre-25S RNAs suggestive of a protected spacer fragment of similar length. PMID:22083961

Prevention of disabling back injuries in nurses by the use of mechanical patient lift systems.

PubMed

Edlich, Richard F; Winters, Kathryne L; Hudson, Mary Anne; Britt, L D; Long, William B

2004-01-01

immediately has resulted in numerous denials of claims for rehabilitation and compensation that nurses deserve. Experts believe that training in proper body mechanics does not prevent back injury. Consequently, focus has been placed on other innovative injury prevention programs, including the use of engineering controls as well as the "lift team" method. Ergonomics involves the use of mechanical devices (e.g., walking belt and mechanical hoist) to aid in patient lifting and transferring tasks. Guldmann Inc. has devised ceiling lift systems and slings during the past 20 years. They have successfully completed thousands of installations worldwide, covering a wide range of challenging conditions and complex environments. The Guldmann ceiling-mounted hoist system consists of a wide range of lifting units, rail components, and a complete assortment of lifting slings and accessories. Its sling is made of polyester, which is characterized by its strength and elasticity. It retains its shape and is dirt repellent and easy to maintain. The Guldmann network has one of the largest and indisputably most experienced group of certified installers in the United States. The "lift team" method was devised to remove nursing personnel from the everyday task of moving patients. This type of intervention assumes that lifting is a specialized skill to be performed only by expert professional patient movers who have been thoroughly trained in the latest lifting device techniques.

Chronic Widespread Back Pain is Distinct From Chronic Local Back Pain: Evidence From Quantitative Sensory Testing, Pain Drawings, and Psychometrics.

PubMed

Gerhardt, Andreas; Eich, Wolfgang; Janke, Susanne; Leisner, Sabine; Treede, Rolf-Detlef; Tesarz, Jonas

2016-07-01

Whether chronic localized pain (CLP) and chronic widespread pain (CWP) have different mechanisms or to what extent they overlap in their pathophysiology is controversial. The study compared quantitative sensory testing profiles of nonspecific chronic back pain patients with CLP (n=48) and CWP (n=29) with and fibromyalgia syndrome (FMS) patients (n=90) and pain-free controls (n = 40). The quantitative sensory testing protocol of the "German-Research-Network-on-Neuropathic-Pain" was used to measure evoked pain on the painful area in the lower back and the pain-free hand (thermal and mechanical detection and pain thresholds, vibration threshold, pain sensitivity to sharp and blunt mechanical stimuli). Ongoing pain and psychometrics were captured with pain drawings and questionnaires. CLP patients did not differ from pain-free controls, except for lower pressure pain threshold (PPT) on the back. CWP and FMS patients showed lower heat pain threshold and higher wind-up ratio on the back and lower heat pain threshold and cold pain threshold on the hand. FMS showed lower PPT on back and hand, and higher comorbidity of anxiety and depression and more functional impairment than all other groups. Even after long duration CLP presents with a local hypersensitivity for PPT, suggesting a somatotopically specific sensitization of nociceptive processing. However, CWP patients show widespread ongoing pain and hyperalgesia for different stimuli that is generalized in space, suggesting the involvement of descending control systems, as also suggested for FMS patients. Because mechanisms in nonspecific chronic back pain with CLP and CWP differ, these patients should be distinguished in future research and allocated to different treatments.

Implementation of a Quality Improvement Process Aimed to Deliver Higher-Value Physical Therapy for Patients With Low Back Pain: Case Report.

PubMed

Karlen, Emily; McCathie, Becky

2015-12-01

The current state of health care demands higher-value care. Due to many barriers, clinicians routinely do not implement evidence-based care even though it is known to improve quality and reduce cost of care. The purpose of this case report is to describe a theory-based, multitactic implementation of a quality improvement process aimed to deliver higher-value physical therapy for patients with low back pain. Patients were treated from January 2010 through December 2014 in 1 of 32 outpatient physical therapy clinics within an academic health care system. Data were examined from 47,755 patients (mean age=50.3 years) entering outpatient physical therapy for management of nonspecific low back pain, with or without radicular pain. Development and implementation tactics were constructed from adult learning and change management theory to enhance adherence to best practice care among 130 physical therapists. A quality improvement team implemented 4 tactics: establish care delivery expectations, facilitate peer-led clinical and operational teams, foster a learning environment focused on meeting a population's needs, and continuously collect and analyze outcomes data. Physical therapy utilization and change in functional disability were measured to assess relative cost and quality of care. Secondarily, charge data assessed change in physical therapists' application of evidence-based care. Implementation of a quality improvement process was measured by year-over-year improved clinical outcomes, decreased utilization, and increased adherence to evidence-based physical therapy, which was associated with higher-value care. When adult learning and change management theory are combined in quality improvement efforts, common barriers to implementing evidence-based care can be overcome, creating an environment supportive of delivering higher-value physical therapy for patients with low back pain. © 2015 American Physical Therapy Association.

Low back pain.

PubMed Central

Ehrlich, George E.

2003-01-01

Low back pain is a leading cause of disability. It occurs in similar proportions in all cultures, interferes with quality of life and work performance, and is the most common reason for medical consultations. Few cases of back pain are due to specific causes; most cases are non-specific. Acute back pain is the most common presentation and is usually self-limiting, lasting less than three months regardless of treatment. Chronic back pain is a more difficult problem, which often has strong psychological overlay: work dissatisfaction, boredom, and a generous compensation system contribute to it. Among the diagnoses offered for chronic pain is fibromyalgia, an urban condition (the diagnosis is not made in rural settings) that does not differ materially from other instances of widespread chronic pain. Although disc protrusions detected on X-ray are often blamed, they rarely are responsible for the pain, and surgery is seldom successful at alleviating it. No single treatment is superior to others; patients prefer manipulative therapy, but studies have not demonstrated that it has any superiority over others. A WHO Advisory Panel has defined common outcome measures to be used to judge the efficacy of treatments for studies. PMID:14710509

End-to-end security for personal telehealth.

PubMed

Koster, Paul; Asim, Muhammad; Petkovic, Milan

2011-01-01

Personal telehealth is in rapid development with innovative emerging applications like disease management. With personal telehealth people participate in their own care supported by an open distributed system with health services. This poses new end-to-end security and privacy challenges. In this paper we introduce new end-to-end security requirements and present a design for consent management in the context of the Continua Health Alliance architecture. Thus, we empower patients to control how their health information is shared and used in a personal telehealth eco-system.

Backing warning sensors for tow plows.

DOT National Transportation Integrated Search

2013-06-01

Backup warning system devices were evaluated to determine if they would alert winter maintenance snow : plow drivers to obstacles directly behind the trailer and out of view of the driver when a unit is backed up. : When the sensors on the back of th...

Cyberinfrastructure to support Real-time, End-to-End, High Resolution, Localized Forecasting

NASA Astrophysics Data System (ADS)

Ramamurthy, M. K.; Lindholm, D.; Baltzer, T.; Domenico, B.

2004-12-01

From natural disasters such as flooding and forest fires to man-made disasters such as toxic gas releases, the impact of weather-influenced severe events on society can be profound. Understanding, predicting, and mitigating such local, mesoscale events calls for a cyberinfrastructure to integrate multidisciplinary data, tools, and services as well as the capability to generate and use high resolution data (such as wind and precipitation) from localized models. The need for such end to end systems -- including data collection, distribution, integration, assimilation, regionalized mesoscale modeling, analysis, and visualization -- has been realized to some extent in many academic and quasi-operational environments, especially for atmospheric sciences data. However, many challenges still remain in the integration and synthesis of data from multiple sources and the development of interoperable data systems and services across those disciplines. Over the years, the Unidata Program Center has developed several tools that have either directly or indirectly facilitated these local modeling activities. For example, the community is using Unidata technologies such as the Internet Data Distribution (IDD) system, Local Data Manger (LDM), decoders, netCDF libraries, Thematic Realtime Environmental Distributed Data Services (THREDDS), and the Integrated Data Viewer (IDV) in their real-time prediction efforts. In essence, these technologies for data reception and processing, local and remote access, cataloging, and analysis and visualization coupled with technologies from others in the community are becoming the foundation of a cyberinfrastructure to support an end-to-end regional forecasting system. To build on these capabilities, the Unidata Program Center is pleased to be a significant contributor to the Linked Environments for Atmospheric Discovery (LEAD) project, a NSF-funded multi-institutional large Information Technology Research effort. The goal of LEAD is to create an

Realization of back-side heterogeneous hybrid III-V/Si DBR lasers for silicon photonics

NASA Astrophysics Data System (ADS)

Durel, Jocelyn; Ferrotti, Thomas; Chantre, Alain; Cremer, Sébastien; Harduin, Julie; Bernabé, Stéphane; Kopp, Christophe; Boeuf, Frédéric; Ben Bakir, Badhise; Broquin, Jean-Emmanuel

2016-02-01

In this paper, the simulation, design and fabrication of a back-side coupling (BSC) concept for silicon photonics, which targets heterogeneous hybrid III-V/Si laser integration is presented. Though various demonstrations of a complete SOI integration of passive and active photonic devices have been made, they all feature multi-level planar metal interconnects, and a lack of integrated light sources. This is mainly due to the conflict between the need of planar surfaces for III-V/Si bonding and multiple levels of metallization. The proposed BSC solution to this topographical problem consists in fabricating lasers on the back-side of the Si waveguides using a new process sequence. The devices are based on a hybrid structure composed of an InGaAsP MQW active area and a Si-based DBR cavity. The emitted light wavelength is accordable within a range of 20 nm around 1.31μm thanks to thermal heaters and the laser output is fiber coupled through a Grating Coupler (GC). From a manufacturing point of view, the BSC approach provides not only the advantages of allowing the use of a thin-BOX SOI instead of a thick one; but it also shifts the laser processing steps and their materials unfriendly to CMOS process to the far back-end areas of fabrication lines. Moreover, aside from solving technological integration issues, the BSC concept offers several new design opportunities for active and passive devices (heat sink, Bragg gratings, grating couplers enhanced with integrated metallic mirrors, tapers…). These building boxes are explored here theoretically and experimentally.

Navigating Earthquake Physics with High-Resolution Array Back-Projection

NASA Astrophysics Data System (ADS)

Meng, Lingsen

Understanding earthquake source dynamics is a fundamental goal of geophysics. Progress toward this goal has been slow due to the gap between state-of-art earthquake simulations and the limited source imaging techniques based on conventional low-frequency finite fault inversions. Seismic array processing is an alternative source imaging technique that employs the higher frequency content of the earthquakes and provides finer detail of the source process with few prior assumptions. While the back-projection provides key observations of previous large earthquakes, the standard beamforming back-projection suffers from low resolution and severe artifacts. This thesis introduces the MUSIC technique, a high-resolution array processing method that aims to narrow the gap between the seismic observations and earthquake simulations. The MUSIC is a high-resolution method taking advantage of the higher order signal statistics. The method has not been widely used in seismology yet because of the nonstationary and incoherent nature of the seismic signal. We adapt MUSIC to transient seismic signal by incorporating the Multitaper cross-spectrum estimates. We also adopt a "reference window" strategy that mitigates the "swimming artifact," a systematic drift effect in back projection. The improved MUSIC back projections allow the imaging of recent large earthquakes in finer details which give rise to new perspectives on dynamic simulations. In the 2011 Tohoku-Oki earthquake, we observe frequency-dependent rupture behaviors which relate to the material variation along the dip of the subduction interface. In the 2012 off-Sumatra earthquake, we image the complicated ruptures involving orthogonal fault system and an usual branching direction. This result along with our complementary dynamic simulations probes the pressure-insensitive strength of the deep oceanic lithosphere. In another example, back projection is applied to the 2010 M7 Haiti earthquake recorded at regional distance. The

Single-snapshot 2D color measurement by plenoptic imaging system

NASA Astrophysics Data System (ADS)

Masuda, Kensuke; Yamanaka, Yuji; Maruyama, Go; Nagai, Sho; Hirai, Hideaki; Meng, Lingfei; Tosic, Ivana

2014-03-01

Plenoptic cameras enable capture of directional light ray information, thus allowing applications such as digital refocusing, depth estimation, or multiband imaging. One of the most common plenoptic camera architectures contains a microlens array at the conventional image plane and a sensor at the back focal plane of the microlens array. We leverage the multiband imaging (MBI) function of this camera and develop a single-snapshot, single-sensor high color fidelity camera. Our camera is based on a plenoptic system with XYZ filters inserted in the pupil plane of the main lens. To achieve high color measurement precision of this system, we perform an end-to-end optimization of the system model that includes light source information, object information, optical system information, plenoptic image processing and color estimation processing. Optimized system characteristics are exploited to build an XYZ plenoptic colorimetric camera prototype that achieves high color measurement precision. We describe an application of our colorimetric camera to color shading evaluation of display and show that it achieves color accuracy of ΔE<0.01.

Process Capability of High Speed Micro End-Milling of Inconel 718 with Minimum Quantity Lubrication

NASA Astrophysics Data System (ADS)

Rahman, Mohamed Abd; Yeakub Ali, Mohammad; Rahman Shah Rosli, Abdul; Banu, Asfana

2017-03-01

The demand for micro-parts is expected to grow and micro-machining has been shown to be a viable manufacturing process to produce these products. These micro-products may be produced from hard-to-machine materials such as superalloys under little or no metal cutting fluids to reduce machining cost or drawbacks associated with health and environment. This project aims to investigate the capability of micro end-milling process of Inconel 718 with minimum quantity lubrication (MQL). Microtools DT-110 multi-process micro machine was used to machine 10 micro-channels with MQL and 10 more under dry condition while maintaining the same machining parameters. The width of the micro-channels was measured using digital microscope and used to determine the process capability indices, Cp and Cpk. QI Macros SPC for Excel was used to analyze the resultant machining data. The results indicated that micro end-milling process of Inconel 718 was not capable under both MQL and dry cutting conditions as indicated by the Cp values of less than 1.0. However, the use of MQL helped the process to be more stable and capable. Results obtained showed that the process variation was greatly reduced by using MQL in micro end-milling of Inconel 718.

Some fundamental questions about the evolution of the Sea of Japan back-arc

NASA Astrophysics Data System (ADS)

Van Horne, A.; Sato, H.; Ishiyama, T.

2016-12-01

The Japanese island arc separated from Asia through the rifting of an active continental margin, and the opening of the Sea of Japan back-arc, in the middle Miocene. Due to its complex tectonic setting, the Sea of Japan back-arc was affected by multiple external events contemporary with its opening, including a plate reorganization, the opening of at least two other nearby back-arcs (Shikoku Basin and Okhotsk Sea/Kuril Basin), and two separate arc-arc collisions, involving encroachment upon Japan of the Izu-Bonin and Kuril arcs. Recent tectonic inversion has exposed entire sequences of back-arc structure on land, which remain virtually intact because of the short duration of inversion. Japan experiences a high level of seismic activity due to its position on the overriding plate of an active subduction margin. Continuous geophysical monitoring via a dense nationwide seismic/geodetic network, and a program of controlled-source refraction/wide-angle reflection profiling, directed towards earthquake hazard mitigation, have made it the repository of a rich geophysical data set through which to understand the processes that have shaped back-arc development. Timing, structural evolution, and patterns of magmatic activity during back-arc opening in the Sea of Japan were established by earlier investigations, but fundamental questions regarding back-arc development remain outstanding. These include (1) timing of the arrival of the Philippine Sea plate in southwest Japan, (2) the nature of the plate boundary prior to its arrival, (3) the pre-rift location of the Japanese island arc when it was attached to Asia, (4) the mechanism of back-arc opening (pull-apart or trench retreat), (5) the speed of opening, (6) simultaneous or sequential development of the multi-rift system, (7) the origin of the anomalously thick Yamato Basin ocean crust, and (8) the pattern of concentrated deformation in the failed-rift system of the eastern Sea of Japan since tectonic inversion. Resolving

A common type system for clinical natural language processing

PubMed Central

2013-01-01

Background One challenge in reusing clinical data stored in electronic medical records is that these data are heterogenous. Clinical Natural Language Processing (NLP) plays an important role in transforming information in clinical text to a standard representation that is comparable and interoperable. Information may be processed and shared when a type system specifies the allowable data structures. Therefore, we aim to define a common type system for clinical NLP that enables interoperability between structured and unstructured data generated in different clinical settings. Results We describe a common type system for clinical NLP that has an end target of deep semantics based on Clinical Element Models (CEMs), thus interoperating with structured data and accommodating diverse NLP approaches. The type system has been implemented in UIMA (Unstructured Information Management Architecture) and is fully functional in a popular open-source clinical NLP system, cTAKES (clinical Text Analysis and Knowledge Extraction System) versions 2.0 and later. Conclusions We have created a type system that targets deep semantics, thereby allowing for NLP systems to encapsulate knowledge from text and share it alongside heterogenous clinical data sources. Rather than surface semantics that are typically the end product of NLP algorithms, CEM-based semantics explicitly build in deep clinical semantics as the point of interoperability with more structured data types. PMID:23286462

Loran digital phase-locked loop and RF front-end system error analysis

NASA Technical Reports Server (NTRS)

Mccall, D. L.

1979-01-01

An analysis of the system performance of the digital phase locked loops (DPLL) and RF front end that are implemented in the MINI-L4 Loran receiver is presented. Three of the four experiments deal with the performance of the digital phase locked loops. The other experiment deals with the RF front end and DPLL system error which arise in the front end due to poor signal to noise ratios. The ability of the DPLLs to track the offsets is studied.

Returning to work - a long-term process reaching beyond the time frames of multimodal non-specific back pain rehabilitation.

PubMed

Hellman, Therese; Jensen, Irene; Bergström, Gunnar; Busch, Hillevi

2015-01-01

To explore and describe health professionals' experience of working with return to work (RTW) in multimodal rehabilitation for people with non-specific back pain. An interview study using qualitative content analysis. Fifteen participants were interviewed, all were working with multimodal rehabilitation for people with non-specific back pain in eight different rehabilitation units. The participants experienced RTW as a long-term process reaching beyond the time frames of the multimodal rehabilitation (MMR). Their attitudes and, their patients' condition, impacted on their work which focused on psychological and physical well-being as well as participation in everyday life. They often created an action plan for the RTW process, however the responsibility for its realisation was transferred to other actors. The participants described limited interventions in connection with patients' workplaces. Recommended support in the RTW process in MMR comprises the provision of continuous supervision of vocational issues for the health care professionals, the development of guidelines and a checklist for how to work in close collaboration with patients' workplaces and employers, the provision of long-term follow-up in relation to the patients' work, and the development of proper interventions in order to promote transitions between all the different actors involved. Rehabilitation programs targeting return to work (RTW) for people with non-specific back pain needs to include features concretely focusing on vocational issues. Health and RTW is often seen as a linear process in which health comes before RTW. Rehabilitation programs could be tailored to better address the reciprocal relationship between health and work, in which they are interconnected and affect each other. The RTW process is reaching beyond the time frames of the multimodal rehabilitation but further support from the patients are asked for. The rehabilitation programs needs to be designed to provide long

Studies of corona and back discharges in carbon dioxide

NASA Astrophysics Data System (ADS)

Czech, Tadeusz; Sobczyk, Arkadiusz Tomasz; Jaworek, Anatol; Krupa, Andrzej; Rajch, Eryk

2013-01-01

Results of spectroscopic investigations and current-voltage characteristics of corona and back discharges generated in point-plane electrode geometry in CO2 at atmospheric pressure for positive and negative polarity of the discharge electrode are presented in the paper. Three forms of back discharge, for both polarities, were investigated: glow, streamer and low-current back-arc. To generate the back-discharges for the conditions similar to electrostatic precipitator, the plate electrode was covered with fly ash layer. In order to characterize back discharge processes, the emission spectra were measured and compared with those obtained for normal discharge, generated in the same electrode configuration but without the fly ash layer on the plate electrode. The measurements have shown that optical emission spectral lines of atoms and molecules, excited or ionised in back discharge, depend on the forms of the discharge, the discharge current, and are different in the zones close to needle electrode and fly ash layer. From the comparison of spectral lines of back and normal discharges, an effect of fly ash layer on discharge characteristics and morphology has been determined. In normal corona, the emission spectra are mainly predetermined by the working gas components, but in the case of back discharge, the atomic and molecular lines, resulting from chemical composition of fly ash, are also identified. Differences in the spectra of back discharge for positive and negative polarities of the needle electrode have been explained by considering the kind of ions generated in the crater in fly ash layer. For back arc, the emission of spectral lines of atoms and molecules from fly ash layer can be recorded in the crater zone, but in the needle zone, only the emission lines of CO2 and its decomposition products (CO and C2) can be noticed. The studies of back discharge in CO2, as one of the main components of flue gases, were undertaken because this type of discharge, after

End users transforming experiences into formal information and process models for personalised health interventions.

PubMed

Lindgren, Helena; Lundin-Olsson, Lillemor; Pohl, Petra; Sandlund, Marlene

2014-01-01

Five physiotherapists organised a user-centric design process of a knowledge-based support system for promoting exercise and preventing falls. The process integrated focus group studies with 17 older adults and prototyping. The transformation of informal medical and rehabilitation expertise and older adults' experiences into formal information and process models during the development was studied. As tool they used ACKTUS, a development platform for knowledge-based applications. The process became agile and incremental, partly due to the diversity of expectations and preferences among both older adults and physiotherapists, and the participatory approach to design and development. In addition, there was a need to develop the knowledge content alongside with the formal models and their presentations, which allowed the participants to test hands-on and evaluate the ideas, content and design. The resulting application is modular, extendable, flexible and adaptable to the individual end user. Moreover, the physiotherapists are able to modify the information and process models, and in this way further develop the application. The main constraint was found to be the lack of support for the initial phase of concept modelling, which lead to a redesigned user interface and functionality of ACKTUS.

Towards a Software Framework to Support Deployment of Low Cost End-to-End Hydroclimatological Sensor Network

NASA Astrophysics Data System (ADS)

Celicourt, P.; Piasecki, M.

2015-12-01

Deployment of environmental sensors assemblies based on cheap platforms such as Raspberry Pi and Arduino have gained much attention over the past few years. While they are more attractive due to their ability to be controlled with a few programming language choices, the configuration task can become quite complex due to the need of having to learn several different proprietary data formats and protocols which constitute a bottleneck for the expansion of sensor network. In response to this rising complexity the Institute of Electrical and Electronics Engineers (IEEE) has sponsored the development of the IEEE 1451 standard in an attempt to introduce a common standard. The most innovative concept of the standard is the Transducer Electronic Data Sheet (TEDS) which enables transducers to self-identify, self-describe, self-calibrate, to exhibit plug-and-play functionality, etc. We used Python to develop an IEEE 1451.0 platform-independent graphical user interface to generate and provide sufficient information about almost ANY sensor and sensor platforms for sensor programming purposes, automatic calibration of sensors data, incorporation of back-end demands on data management in TEDS for automatic standard-based data storage, search and discovery purposes. These features are paramount to make data management much less onerous in large scale sensor network. Along with the TEDS Creator, we developed a tool namely HydroUnits for three specific purposes: encoding of physical units in the TEDS, dimensional analysis, and on-the-fly conversion of time series allowing users to retrieve data in a desired equivalent unit while accommodating unforeseen and user-defined units. In addition, our back-end data management comprises the Python/Django equivalent of the CUAHSI Observations Data Model (ODM) namely DjangODM that will be hosted by a MongoDB Database Server which offers more convenience for our application. We are also developing a data which will be paired with the data

Ligation-mediated PCR with a back-to-back adapter reduces amplification bias resulting from variations in GC content.

PubMed

Ishihara, Satoru; Kotomura, Naoe; Yamamoto, Naoki; Ochiai, Hiroshi

2017-08-15

Ligation-mediated polymerase chain reaction (LM-PCR) is a common technique for amplification of a pool of DNA fragments. Here, a double-stranded oligonucleotide consisting of two primer sequences in back-to-back orientation was designed as an adapter for LM-PCR. When DNA fragments were ligated with this adapter, the fragments were sandwiched between two adapters in random orientations. In the ensuing PCR, ligation products linked at each end to an opposite side of the adapter, i.e. to a distinct primer sequence, were preferentially amplified compared with products linked at each end to an identical primer sequence. The use of this adapter in LM-PCR reduced the impairment of PCR by substrate DNA with a high GC content, compared with the use of traditional LM-PCR adapters. This result suggested that our method has the potential to contribute to reduction of the amplification bias that is caused by an intrinsic property of the sequence context in substrate DNA. A DNA preparation obtained from a chromatin immunoprecipitation assay using pulldown of a specific form of histone H3 was successfully amplified using the modified LM-PCR, and the amplified products could be used as probes in a fluorescence in situ hybridization analysis. Copyright © 2017 Elsevier Inc. All rights reserved.

Mechanical end joint system for connecting structural column elements

NASA Technical Reports Server (NTRS)

Bush, Harold G. (Inventor); Mikulas, Martin M., Jr. (Inventor); Wallsom, Richard E. (Inventor)

1990-01-01

A mechanical end joint system is presented that eliminates the possibility of free movements between the joint halves during loading or vibration. Both node joint body (NJB) and column end joint body (CEJB) have cylindrical engaging ends. Each of these ends has an integral semicircular tongue and groove. The two joint halves are engaged transversely - the tongue of the NJB mating with the groove of the CEJB and vice versa. The joint system employs a spring loaded internal latch mechanism housed in the CEJB. During mating, this mechanism is pushed away from the NJB and enters the NJB when mating is completed. In order to lock the joint and add a preload across the tongue and groove faces, an operating ring collar is rotated through 45 deg causing an internal mechanism to compress a Belleville washer preload mechanism. This causes an equal and opposite force to be exerted on the latch bolt and the latch plunger. This force presses the two joint halves tightly together. In order to prevent inadvertent disassembly, a secondary lock is also engaged when the joint is closed. Plungers are carried in the operating ring collar. When the joint is closed, the plungers fall into tracks on the CEJB, which allows the joint to be opened only when the operating ring collar and plungers are pushed directly away from the joining end. One application of this invention is the rapid assembly and disassembly of diverse skeletal framework structures which is extremely important in many projects involving the exploration of space.

5. INSTRUMENT ROOM INTERIOR, SHOWING BACKS OF CONSOLE LOCKERS. Looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. INSTRUMENT ROOM INTERIOR, SHOWING BACKS OF CONSOLE LOCKERS. Looking northeast to firing control room passageway. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Firing Control Building, Test Area 1-100, northeast end of Test Area 1-100 Road, Boron, Kern County, CA

Lumbar Disc Screening Using Back Pain Questionnaires: Oswestry Low Back Pain Score, Aberdeen Low Back Pain Scale, and Acute Low Back Pain Screening Questionnaire

PubMed Central

Kim, Do Yeon; Oh, Chang Hyun; Park, Hyung Chun; Park, Chong Oon

2012-01-01

Objective To evaluate the usefulness of back pain questionnaires for lumbar disc screening among Korean young males. Methods We carried out a survey for lumbar disc screening through back pain questionnaires among the volunteers with or without back pain. Three types of back pain questionnaire (Oswestry Low Back Pain Score, Aberdeen Low Back Pain Scale, and Acute Low Back Pain Screeing Questionnaire) were randomly assigned to the examinees. The authors reviewed lumbar imaging studies (simple lumbar radiographs, lumbar computed tomography, and magnetic resolutional images), and the severity of lumbar disc herniation was categorized according to the guidelines issued by the Korean military directorate. We calculated the relationship between the back pain questionnaire scores and the severity of lumbar disc herniation. Results The scores of back pain questionnaires increased according to the severity of lumbar disc herniation. But, the range of scores was very vague, so it is less predictable to detect lumbar disc herniation using only back pain questionnaires. The sensitivity between the back pain questionnaires and the presence of lumbar disc herniation was low (16-64%). Conclusion Screening of lumbar disc herniation using only back pain questionnaires has limited value. PMID:25983807

Back Injuries

MedlinePlus

... to your pelvis. Back injuries can result from sports injuries, work around the house or in the garden, or a sudden jolt such as a car accident. The lower back is the most common site of back injuries and back pain. Common ...

Designed drug-release systems having various breathable polyurethane film-backed hydrocolloid acrylated adhesive layers for moisture healing.

PubMed

Chang, Ching-Hsien; Liu, Hsia-Wei; Huang, Ching-Cheng

2014-01-01

A series of designed drug-release systems were prepared and established for clear moisture healing. These systems were designed to have an interpenetrating polymer network (IPN) structure, which contained a breathable polyurethane film, hydrocolloidlayer, and polyacrylate adhesive layer. Breathable polyurethane film (2000 g/m(2)/24 hr) with high moisture permeability was employed as a base for new drug-release systems or wound dressings. All drug-release systems having a polyurethane film-backed hydrocolloid acrylated adhesive layer showed an increase of water uptakes with increasing time. After 114 hours, high water uptakes of drug-release systems with 20% hydrocolloid components were observed in the values of 160, 1100, and 1870% for different additional hydrocolloid components of carboxymethylcellulose, sodium alginate, and carbomer U10, respectively. New drug-release systems of polyurethane film-backed hydrocolloid/adhesive layers could be designed and established for wound care managements.

Leadership, institution building and pay-back of health systems research in Mexico

PubMed Central

González-Block, Miguel Angel

2009-01-01

Background Health systems research is being increasingly called upon to support scaling up of disease control interventions and to support rapid health sector change. Yet research capacity building and pay-back take years or even decades to be demonstrated, while leadership and institution building are critical for their success. The case of Mexico can be illustrative for middle income countries and emerging economies striving to build health research systems. Methods Historical reflection suggests the relationship between health sector reforms and economic crisis, on the one hand, and research capacity building and payback, on the other. Mexico's post-revolutionary background and its three health sector reforms are analyzed to identify the emphases given to health systems research. Results The first wave of health reform in the 1940s emphasized clinical and epidemiological research. Health systems research was not encouraged in a context of rapid economic development and an authoritarian regime. In contrast, health systems research was given a privileged place with the second wave of health reforms in the 1980s, which addressed health system coordination, decentralization and the universal right to health in a context of a deep economic crisis. The third wave of health reforms between 2003 and 2006 was based on the health system models proposed through research in the 90s. The credibility gained by research institutions was critical to ensure government uptake. Research influence can be traced through the role it played in defining a problem, in designing innovative insurance mechanisms and in establishing evaluation frameworks. It is argued that the Ministry of Health's budget increase of 56% between 2003 and 2006 and the reductions in inequity are pay-back to research investments since the 1980s. PMID:19793399

Site-specific multipoint fluorescence measurement system with end-capped optical fibers.

PubMed

Song, Woosub; Moon, Sucbei; Lee, Byoung-Cheol; Park, Chul-Seung; Kim, Dug Young; Kwon, Hyuk Sang

2011-07-10

We present the development and implementation of a spatially and spectrally resolved multipoint fluorescence correlation spectroscopy (FCS) system utilizing multiple end-capped optical fibers and an inexpensive laser source. Specially prepared end-capped optical fibers placed in an image plane were used to both collect fluorescence signals from the sample and to deliver signals to the detectors. The placement of independently selected optical fibers on the image plane was done by monitoring the end-capped fiber tips at the focus using a CCD, and fluorescence from specific positions of a sample were collected by an end-capped fiber, which could accurately represent light intensities or spectral data without incurring any disturbance. A fast multipoint spectroscopy system with a time resolution of ∼1.5 ms was then implemented using a prism and an electron multiplying charge coupled device with a pixel binning for the region of interest. The accuracy of our proposed system was subsequently confirmed by experimental results, based on an FCS analysis of microspheres in distilled water. We expect that the proposed multipoint site-specific fluorescence measurement system can be used as an inexpensive fluorescence measurement tool to study many intracellular and molecular dynamics in cell biology. © 2011 Optical Society of America

40 CFR 63.496 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2012 CFR

2012-07-01

... methods of determining this quantity are production records, measurement of stream characteristics, and... HAP (or TOC, minus methane and ethane) emissions in all process vent streams and primary and secondary... heater. (B) Paragraph (b)(5)(iii) of this section is applicable, except that TOC (minus methane and...

40 CFR 63.496 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2014 CFR

2014-07-01

... methods of determining this quantity are production records, measurement of stream characteristics, and... HAP (or TOC, minus methane and ethane) emissions in all process vent streams and primary and secondary... heater. (B) Paragraph (b)(5)(iii) of this section is applicable, except that TOC (minus methane and...

40 CFR 63.496 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2011 CFR

2011-07-01

... methods of determining this quantity are production records, measurement of stream characteristics, and... HAP (or TOC, minus methane and ethane) emissions in all process vent streams and primary and secondary... heater. (B) Paragraph (b)(5)(iii) of this section is applicable, except that TOC (minus methane and...

40 CFR 63.496 - Back-end process provisions-procedures to determine compliance with residual organic HAP...

Code of Federal Regulations, 2013 CFR

2013-07-01

... methods of determining this quantity are production records, measurement of stream characteristics, and... HAP (or TOC, minus methane and ethane) emissions in all process vent streams and primary and secondary... heater. (B) Paragraph (b)(5)(iii) of this section is applicable, except that TOC (minus methane and...

Experience with chemical system decontamination by the CORD process and electrochemical decontamination of pipe ends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wille, H.; Bertholdt, H.O.; Operschall, H.

Efforts to reduce occupational radiation exposure during inspection and repair work in nuclear power plants turns steadily increasing attention to the decontamination of systems and components. Due to the advanced age of nuclear power plants resulting in increasing dose rates, the decontamination of components, or rather of complete systems, or loops to protect operating and inspection personnel becomes demanding. Besides, decontaminating complete primary loops is in many cases less difficult than cleaning large components. Based on experience gained in nuclear power plants, an outline of two different decontamination methods performed recently are given. For the decontamination of complete systems ormore » loops, Kraftwerk Union AG has developed CORD, a low-concentration process. For the decontamination performance of a subsystem, such as the steam generator (SG) channel heads of a pressurized water reactor or the recirculation loops of a boiling water reactor the automated mobile decontamination appliance is used. The electrochemical decontamination process is primarily applicable for the treatment of specially limited surface areas.« less

Serial Back-Plane Technologies in Advanced Avionics Architectures

NASA Technical Reports Server (NTRS)

Varnavas, Kosta

2005-01-01

Current back plane technologies such as VME, and current personal computer back planes such as PCI, are shared bus systems that can exhibit nondeterministic latencies. This means a card can take control of the bus and use resources indefinitely affecting the ability of other cards in the back plane to acquire the bus. This provides a real hit on the reliability of the system. Additionally, these parallel busses only have bandwidths in the 100s of megahertz range and EMI and noise effects get worse the higher the bandwidth goes. To provide scalable, fault-tolerant, advanced computing systems, more applicable to today s connected computing environment and to better meet the needs of future requirements for advanced space instruments and vehicles, serial back-plane technologies should be implemented in advanced avionics architectures. Serial backplane technologies eliminate the problem of one card getting the bus and never relinquishing it, or one minor problem on the backplane bringing the whole system down. Being serial instead of parallel improves the reliability by reducing many of the signal integrity issues associated with parallel back planes and thus significantly improves reliability. The increased speeds associated with a serial backplane are an added bonus.

End-User Evaluations of Semantic Web Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCool, Rob; Cowell, Andrew J.; Thurman, David A.

Stanford University's Knowledge Systems Laboratory (KSL) is working in partnership with Battelle Memorial Institute and IBM Watson Research Center to develop a suite of technologies for information extraction, knowledge representation & reasoning, and human-information interaction, in unison entitled 'Knowledge Associates for Novel Intelligence' (KANI). We have developed an integrated analytic environment composed of a collection of analyst associates, software components that aid the user at different stages of the information analysis process. An important part of our participatory design process has been to ensure our technologies and designs are tightly integrate with the needs and requirements of our end users,more » To this end, we perform a sequence of evaluations towards the end of the development process that ensure the technologies are both functional and usable. This paper reports on that process.« less

Capitated risk-bearing managed care systems could improve end-of-life care.

PubMed

Lynn, J; Wilkinson, A; Cohn, F; Jones, S B

1998-03-01

Capitated or salaried managed care systems offer an important opportunity to provide high quality, cost-effective end-of-life care. However, capitated healthcare delivery systems have strong incentives to avoid patient populations in need of such care. Care currently provided at the end of life in fee-for-service practice is commonly deficient, with high rates of avoidable pain and other burdens. Only hospice offers a better track record, yet access to hospice is limited, and length of stay is short. Traditional staff- or group-model managed care plans, with their emphasis on prevention, patient education, cost efficiency, service coordination, and integrated provider networks, present a dynamic set of conditions and organizational structures that would support real change. Advantages derived from managed care systems providing quality end-of-life care include coordinated care across delivery sites, interdisciplinary teams, integrated services, and opportunities to develop innovative care programs, service arrays, utilization controls, and accountability for care standards. We propose a special comprehensive system of managed care, which we call MediCaring, for seriously ill persons nearing the end of life. MediCaring would encompass the best elements of palliative care within a managed care structure: comprehensive, supportive, community-based services that meet personal and medical needs, a focus on patient preferences, symptom management, family counseling, and support. Other programs, such as hospice, have shown that continuity and coordinated care, financed through a capitated payment and directed at a special population, are both feasible and effective. There are obstacles to improving care at the end of life. Managed care systems, like most of medical care, have largely ignored the terminally ill patient. Current financing arrangements make it financially undesirable for insurers to recruit or retain the very sick; very ill patients can be costly over a

The minute virus of mice (MVM) nonstructural protein NS1 induces nicking of MVM DNA at a unique site of the right-end telomere in both hairpin and duplex conformations in vitro.

PubMed

Willwand, K; Baldauf, A Q; Deleu, L; Mumtsidu, E; Costello, E; Beard, P; Rommelaere, J

1997-10-01

The right-end telomere of replicative form (RF) DNA of the autonomous parvovirus minute virus of mice (MVM) consists of a sequence that is self-complementary except for a three nucleotide loop around the axis of symmetry and an interior bulge of three unpaired nucleotides on one strand (designated the right-end 'bubble'). This right-end inverted repeat can exist in the form of a folded-back strand (hairpin conformation) or in an extended form, base-paired to a copy strand (duplex conformation). We recently reported that the right-end telomere is processed in an A9 cell extract supplemented with the MVM nonstructural protein NS1. This processing is shown here to result from the NS1-dependent nicking of the complementary strand at a unique position 21 nt inboard of the folded-back genomic 5' end. DNA species terminating in duplex or hairpin configurations, or in a mutated structure that has lost the right-end bulge, are all cleaved in the presence of NS1, indicating that features distinguishing these structures are not prerequisites for nicking under the in vitro conditions tested. Cleavage of the hairpin structure is followed by strand-displacement synthesis, generating the right-end duplex conformation, while processing of the duplex structure leads to the release of free right-end telomeres. In the majority of molecules, displacement synthesis at the right terminus stops a few nucleotides before reaching the end of the template strand, possibly due to NS1 which is covalently bound to this end. A fraction of the right-end duplex product undergoes melting and re-folding into hairpin structures (formation of a 'rabbit-ear' structure).

Cold-End Subsystem Testing for the Fission Power System Technology Demonstration Unit

NASA Technical Reports Server (NTRS)

Briggs, Mazwell; Gibson, Marc; Ellis, David; Sanzi, James

2013-01-01

The Fission Power System (FPS) Technology Demonstration Unit (TDU) consists of a pumped sodiumpotassium (NaK) loop that provides heat to a Stirling Power Conversion Unit (PCU), which converts some of that heat into electricity and rejects the waste heat to a pumped water loop. Each of the TDU subsystems is being tested independently prior to full system testing at the NASA Glenn Research Center. The pumped NaK loop is being tested at NASA Marshall Space Flight Center; the Stirling PCU and electrical controller are being tested by Sunpower Inc.; and the pumped water loop is being tested at Glenn. This paper describes cold-end subsystem setup and testing at Glenn. The TDU cold end has been assembled in Vacuum Facility 6 (VF 6) at Glenn, the same chamber that will be used for TDU testing. Cold-end testing in VF 6 will demonstrate functionality; validated coldend fill, drain, and emergency backup systems; and generated pump performance and system pressure drop data used to validate models. In addition, a low-cost proof-of concept radiator has been built and tested at Glenn, validating the design and demonstrating the feasibility of using low-cost metal radiators as an alternative to highcost composite radiators in an end-to-end TDU test.

Payload/orbiter signal-processing and data-handling system evaluation

NASA Technical Reports Server (NTRS)

Teasdale, W. E.; Polydoros, A.

1980-01-01

Incompatibilities between orbiter subsystems and payload communication systems to assure that acceptable and to end system performamce will be achieved are identified. The potential incompatabilities are associated with either payloads in the cargo bay or detached payloads communicating with the orbiter via an RF link. The payload signal processing and data handling systems are assessed by investigating interface problems experienced between the inertial upper stage and the orbiter since similar problems are expected for other payloads.

Experience of using MOSFET detectors for dose verification measurements in an end-to-end 192Ir brachytherapy quality assurance system.

PubMed

Persson, Maria; Nilsson, Josef; Carlsson Tedgren, Åsa

Establishment of an end-to-end system for the brachytherapy (BT) dosimetric chain could be valuable in clinical quality assurance. Here, the development of such a system using MOSFET (metal oxide semiconductor field effect transistor) detectors and experience gained during 2 years of use are reported with focus on the performance of the MOSFET detectors. A bolus phantom was constructed with two implants, mimicking prostate and head & neck treatments, using steel needles and plastic catheters to guide the 192 Ir source and house the MOSFET detectors. The phantom was taken through the BT treatment chain from image acquisition to dose evaluation. During the 2-year evaluation-period, delivered doses were verified a total of 56 times using MOSFET detectors which had been calibrated in an external 60 Co beam. An initial experimental investigation on beam quality differences between 192 Ir and 60 Co is reported. The standard deviation in repeated MOSFET measurements was below 3% in the six measurement points with dose levels above 2 Gy. MOSFET measurements overestimated treatment planning system doses by 2-7%. Distance-dependent experimental beam quality correction factors derived in a phantom of similar size as that used for end-to-end tests applied on a time-resolved measurement improved the agreement. MOSFET detectors provide values stable over time and function well for use as detectors for end-to-end quality assurance purposes in 192 Ir BT. Beam quality correction factors should address not only distance from source but also phantom dimensions. Copyright © 2017 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

The software-defined fast post-processing for GEM soft x-ray diagnostics in the Tungsten Environment in Steady-state Tokamak thermal fusion reactor

NASA Astrophysics Data System (ADS)

Krawczyk, Rafał Dominik; Czarski, Tomasz; Linczuk, Paweł; Wojeński, Andrzej; Kolasiński, Piotr; GÄ ska, Michał; Chernyshova, Maryna; Mazon, Didier; Jardin, Axel; Malard, Philippe; Poźniak, Krzysztof; Kasprowicz, Grzegorz; Zabołotny, Wojciech; Kowalska-Strzeciwilk, Ewa; Malinowski, Karol

2018-06-01

This article presents a novel software-defined server-based solutions that were introduced in the fast, real-time computation systems for soft X-ray diagnostics for the WEST (Tungsten Environment in Steady-state Tokamak) reactor in Cadarache, France. The objective of the research was to provide a fast processing of data at high throughput and with low latencies for investigating the interplay between the particle transport and magnetohydrodynamic activity. The long-term objective is to implement in the future a fast feedback signal in the reactor control mechanisms to sustain the fusion reaction. The implemented electronic measurement device is anticipated to be deployed in the WEST. A standalone software-defined computation engine was designed to handle data collected at high rates in the server back-end of the system. Signals are obtained from the front-end field-programmable gate array mezzanine cards that acquire and perform a selection from the gas electron multiplier detector. A fast, authorial library for plasma diagnostics was written in C++. It originated from reference offline MATLAB implementations. They were redesigned for runtime analysis during the experiment in the novel online modes of operation. The implementation allowed the benchmarking, evaluation, and optimization of plasma processing algorithms with the possibility to check the consistency with reference computations written in MATLAB. The back-end software and hardware architecture are presented with data evaluation mechanisms. The online modes of operation for the WEST are discussed. The results concerning the performance of the processing and the introduced functionality are presented.

UCMS - A new signal parameter measurement system using digital signal processing techniques. [User Constraint Measurement System

NASA Technical Reports Server (NTRS)

Choi, H. J.; Su, Y. T.

1986-01-01

The User Constraint Measurement System (UCMS) is a hardware/software package developed by NASA Goddard to measure the signal parameter constraints of the user transponder in the TDRSS environment by means of an all-digital signal sampling technique. An account is presently given of the features of UCMS design and of its performance capabilities and applications; attention is given to such important aspects of the system as RF interface parameter definitions, hardware minimization, the emphasis on offline software signal processing, and end-to-end link performance. Applications to the measurement of other signal parameters are also discussed.

Study of the back recombination processes of PbS quantum dots sensitized solar cells

NASA Astrophysics Data System (ADS)

Badawi, Ali; Al-Hosiny, N.; Merazga, Amar; Albaradi, Ateyyah M.; Abdallah, S.; Talaat, H.

2016-12-01

In this study, the back recombination processes of PbS quantum dots sensitized solar cells (QDSSCs) has been investigated. PbS QDs were adsorbed onto titania electrodes to act the role of sensitizers using successive ionic layer adsorption and reaction (SILAR) technique. The energy band gaps of the synthesized PbS QDs/titania are ranged from 1.64 eV (corresponding to 756 nm) to 3.12 eV (397 nm) matching the whole visible solar spectrum. The hyperbolic band model (HBM) was used to calculate PbS QDs size and it ranges from 1.76 to 3.44 nm. The photovoltaic parameters (open circuit voltage Voc, short circuit current density Jsc, fill factor FF and efficiency η) of the assembled PbS QDs sensitized solar cells (QDSSCs) were determined under a solar illumination of 100 mW/cm2 (AM 1.5 conditions). The open circuit voltage-decay (OCVD) rates of the assembled PbS QDSSCs were measured. The time constant (τ) for PbS QDSSCs (4 SILAR cycles) shows one order of magnitude larger than that of PbS QDSSCs (8 SILAR cycles) as a result of a decreased electron-hole back recombination.

Evaluation of wheelchair back support crashworthiness: combination wheelchair back support surfaces and attachment hardware.

PubMed

Ha, D; Bertocci, G; Deemer, E; van Roosmalen, L; Karg, P

2000-01-01

Automotive seats are tested for compliance with federal motor vehicle safety standards (FMVSS) to assure safety during impact. Many wheelchair users rely upon their wheelchairs to serve as vehicle seats. However, the crashworthiness of these wheelchairs during impact is often unknown. This study evaluated the crashworthiness of five combinations of wheelchair back support surfaces and attachment hardware using a static test procedure simulating crash loading conditions. The crashworthiness was tested by applying a simulated rearward load to each seat-back system. The magnitude of the applied load was established through computer simulation and biodynamic calculations. None of the five tested wheelchair back supports withstood the simulated crash loads. All failures were associated with attachment hardware.

Tolerance analysis of null lenses using an end-use system performance criterion

NASA Astrophysics Data System (ADS)

Rodgers, J. Michael

2000-07-01

An effective method of assigning tolerances to a null lens is to determine the effects of null-lens fabrication and alignment errors on the end-use system itself, not simply the null lens. This paper describes a method to assign null- lens tolerances based on their effect on any performance parameter of the end-use system.

Minimizing back exchange in the hydrogen exchange-mass spectrometry experiment.

PubMed

Walters, Benjamin T; Ricciuti, Alec; Mayne, Leland; Englander, S Walter

2012-12-01

The addition of mass spectrometry (MS) analysis to the hydrogen exchange (HX) proteolytic fragmentation experiment extends powerful HX methodology to the study of large biologically important proteins. A persistent problem is the degradation of HX information due to back exchange of deuterium label during the fragmentation-separation process needed to prepare samples for MS measurement. This paper reports a systematic analysis of the factors that influence back exchange (solution pH, ionic strength, desolvation temperature, LC column interaction, flow rates, system volume). The many peptides exhibit a range of back exchange due to intrinsic amino acid HX rate differences. Accordingly, large back exchange leads to large variability in D-recovery from one residue to another as well as one peptide to another that cannot be corrected for by reference to any single peptide-level measurement. The usual effort to limit back exchange by limiting LC time provides little gain. Shortening the LC elution gradient by 3-fold only reduced back exchange by ~2%, while sacrificing S/N and peptide count. An unexpected dependence of back exchange on ionic strength as well as pH suggests a strategy in which solution conditions are changed during sample preparation. Higher salt should be used in the first stage of sample preparation (proteolysis and trapping) and lower salt (<20 mM) and pH in the second stage before electrospray injection. Adjustment of these and other factors together with recent advances in peptide fragment detection yields hundreds of peptide fragments with D-label recovery of 90% ± 5%.

Minimizing Back Exchange in the Hydrogen Exchange-Mass Spectrometry Experiment

NASA Astrophysics Data System (ADS)

Walters, Benjamin T.; Ricciuti, Alec; Mayne, Leland; Englander, S. Walter

2012-12-01

The addition of mass spectrometry (MS) analysis to the hydrogen exchange (HX) proteolytic fragmentation experiment extends powerful HX methodology to the study of large biologically important proteins. A persistent problem is the degradation of HX information due to back exchange of deuterium label during the fragmentation-separation process needed to prepare samples for MS measurement. This paper reports a systematic analysis of the factors that influence back exchange (solution pH, ionic strength, desolvation temperature, LC column interaction, flow rates, system volume). The many peptides exhibit a range of back exchange due to intrinsic amino acid HX rate differences. Accordingly, large back exchange leads to large variability in D-recovery from one residue to another as well as one peptide to another that cannot be corrected for by reference to any single peptide-level measurement. The usual effort to limit back exchange by limiting LC time provides little gain. Shortening the LC elution gradient by 3-fold only reduced back exchange by ~2 %, while sacrificing S/N and peptide count. An unexpected dependence of back exchange on ionic strength as well as pH suggests a strategy in which solution conditions are changed during sample preparation. Higher salt should be used in the first stage of sample preparation (proteolysis and trapping) and lower salt (<20 mM) and pH in the second stage before electrospray injection. Adjustment of these and other factors together with recent advances in peptide fragment detection yields hundreds of peptide fragments with D-label recovery of 90 % ± 5 %.

Align the Front End First.

ERIC Educational Resources Information Center

Perry, Jim

1995-01-01

Discussion of management styles and front-end analysis focuses on a review of Douglas McGregor's theories. Topics include Theories X, Y, and Z; leadership skills; motivational needs of employees; intrinsic and extrinsic rewards; and faulty implementation of instructional systems design processes. (LRW)

The Kepler End-to-End Data Pipeline: From Photons to Far Away Worlds

NASA Technical Reports Server (NTRS)

Cooke, Brian; Thompson, Richard; Standley, Shaun

2012-01-01

Launched by NASA on 6 March 2009, the Kepler Mission has been observing more than 100,000 targets in a single patch of sky between the constellations Cygnus and Lyra almost continuously for the last two years looking for planetary systems using the transit method. As of October 2011, the Kepler spacecraft has collected and returned to Earth just over 290 GB of data, identifying 1235 planet candidates with 25 of these candidates confirmed as planets via ground observation. Extracting the telltale signature of a planetary system from stellar photometry where valid signal transients can be small as a 40 ppm is a difficult and exacting task. The end-to end processing of determining planetary candidates from noisy, raw photometric measurements is discussed.

Unmanned Aircraft Systems Minimum Operations Performance Standards End-to-End Verification and Validation (E2-V2) Simulation

NASA Technical Reports Server (NTRS)

Ghatas, Rania W.; Jack, Devin P.; Tsakpinis, Dimitrios; Vincent, Michael J.; Sturdy, James L.; Munoz, Cesar A.; Hoffler, Keith D.; Dutle, Aaron M.; Myer, Robert R.; Dehaven, Anna M.;

Design of Instant Messaging System of Multi-language E-commerce Platform

NASA Astrophysics Data System (ADS)

Yang, Heng; Chen, Xinyi; Li, Jiajia; Cao, Yaru

2017-09-01

This paper aims at researching the message system in the instant messaging system based on the multi-language e-commerce platform in order to design the instant messaging system in multi-language environment and exhibit the national characteristics based information as well as applying national languages to e-commerce. In order to develop beautiful and friendly system interface for the front end of the message system and reduce the development cost, the mature jQuery framework is adopted in this paper. The high-performance server Tomcat is adopted at the back end to process user requests, and MySQL database is adopted for data storage to persistently store user data, and meanwhile Oracle database is adopted as the message buffer for system optimization. Moreover, AJAX technology is adopted for the client to actively pull the newest data from the server at the specified time. In practical application, the system has strong reliability, good expansibility, short response time, high system throughput capacity and high user concurrency.

Open-Ended Questions and the Process Standards

ERIC Educational Resources Information Center

Sanchez, Wendy B.

2013-01-01

Open-ended questions, as discussed in this article, are questions that can be solved or explained in a variety of ways, that focus on conceptual aspects of mathematics, and that have the potential to expose students' understanding and misconceptions. When working with teachers who are using open-ended questions with their students for the…

Back-junction back-contact n-type silicon solar cell with diffused boron emitter locally blocked by implanted phosphorus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Müller, Ralph, E-mail: ralph.mueller@ise.fraunhofer.de; Schrof, Julian; Reichel, Christian

2014-09-08

The highest energy conversion efficiencies in the field of silicon-based photovoltaics have been achieved with back-junction back-contact (BJBC) silicon solar cells by several companies and research groups. One of the most complex parts of this cell structure is the fabrication of the locally doped p- and n-type regions, both on the back side of the solar cell. In this work, we introduce a process sequence based on a synergistic use of ion implantation and furnace diffusion. This sequence enables the formation of all doped regions for a BJBC silicon solar cell in only three processing steps. We observed that implantedmore » phosphorus can block the diffusion of boron atoms into the silicon substrate by nearly three orders of magnitude. Thus, locally implanted phosphorus can be used as an in-situ mask for a subsequent boron diffusion which simultaneously anneals the implanted phosphorus and forms the boron emitter. BJBC silicon solar cells produced with such an easy-to-fabricate process achieved conversion efficiencies of up to 21.7%. An open-circuit voltage of 674 mV and a fill factor of 80.6% prove that there is no significant recombination at the sharp transition between the highly doped emitter and the highly doped back surface field at the device level.« less

End-of-treatment abstinence self-efficacy, behavioral processes of change, and posttreatment drinking outcomes in Project MATCH.

PubMed

Crouch, Taylor Berens; DiClemente, Carlo C; Pitts, Steven C

2015-09-01

This study evaluated whether alcohol abstinence self-efficacy at the end of alcohol treatment was moderated by utilization of behavioral processes of change (coping activities used during a behavior change attempt). It was hypothesized that self-efficacy would be differentially important in predicting posttreatment drinking outcomes depending on the level of behavioral processes, such that the relation between self-efficacy and outcomes would be stronger for individuals who reported low process use. Analyses were also estimated with end-of-treatment abstinence included as a covariate. Data were analyzed from alcohol-dependent individuals in both treatment arms of Project MATCH (Matching Alcoholism Treatments to Client Heterogeneity; N = 1,328), a large alcohol treatment study. Self-efficacy was moderated by behavioral process use in predicting drinking frequency 6 and 12 months posttreatment and drinking quantity 6 months posttreatment such that self-efficacy was more strongly related to posttreatment drinking when low levels of processes were reported than high levels, but interactions were attenuated when end-of-treatment abstinence was controlled for. Significant quadratic relations between end-of-treatment self-efficacy and 6- and 12-month posttreatment drinking quantity and frequency were found (p < .001, ƒ² = 0.02-0.03), such that self-efficacy most robustly predicted outcomes when high. These effects remained significant when end-of-treatment abstinence was included as a covariate. Findings highlight the complex nature of self-efficacy's relation with drinking outcomes. Although the interaction between self-efficacy and behavioral processes was attenuated when end-of-treatment abstinence was controlled for, the quadratic effect of self-efficacy on outcomes remained significant. The pattern of these effects did not support the idea of "overconfidence" as a negative indicator. (c) 2015 APA, all rights reserved).

Friction Stir Back Extrusion of Aluminium Alloys for Automotive Applications

NASA Astrophysics Data System (ADS)

Xu, Zeren

Friction Stir Back Extrusion process, resulting in decreased strength but improved elongation of the processed tubes; a post-process aging step can effectively restore the mechanical properties of the processed tubes by allowing for the reprecipitation of solute elements in the form of fine, dispersed precipitates. Texture analysis performed for AA6063 alloy suggests the dominance of simple shear type textures with clear transition from initial texture to stable B/ ?B components via intermediate types that are stable under moderate strain levels. In order to identify the texture components properly, rigid body rotations are applied to the existing coordinate system to align it to local shear reference frame. Surprisingly, for AA7075 tubes, and fibers are observed to be the dominant texture components in the transition region as well as thermomechanically affected zone while the processing zone is characterized by random texture. The underlying mechanisms responsible for the formation of random texture are discussed in Chapter 5 based on Electron Backscatter Diffraction analysis. Comparative discussions are also carried out for the recrystallization mechanisms that are responsible for grain structure evolution of both alloys. Continuous grain subdivision and reorientation is cited as the dominant mechanism for the recrystallization of AA6063 alloys, while dynamic recrystallization occurs mainly in the form of Geometric Dynamic Recrystallization and progressive subgrain rotations near grain boundaries in AA7075 alloys.

End-to-end Cyberinfrastructure and Data Services for Earth System Science Education and Research: A vision for the future

NASA Astrophysics Data System (ADS)

Ramamurthy, M. K.

2006-05-01

yet revolutionary way of building applications and methods to connect and exchange information over the Web. This new approach, based on XML - a widely accepted format for exchanging data and corresponding semantics over the Internet - enables applications, computer systems, and information processes to work together in fundamentally different ways. Likewise, the advent of digital libraries, grid computing platforms, interoperable frameworks, standards and protocols, open-source software, and community atmospheric models have been important drivers in shaping the use of a new generation of end-to-end cyberinfrastructure for solving some of the most challenging scientific and educational problems. In this talk, I will present an overview of the scientific, technological, and educational landscape, discuss recent developments in cyberinfrastructure, and Unidata's role in and vision for providing easy-to use, robust, end-to-end data services for solving geoscientific problems and advancing student learning.

Electronic hardware design of electrical capacitance tomography systems.

PubMed

Saied, I; Meribout, M

2016-06-28

Electrical tomography techniques for process imaging are very prominent for industrial applications, such as the oil and gas industry and chemical refineries, owing to their ability to provide the flow regime of a flowing fluid within a relatively high throughput. Among the various techniques, electrical capacitance tomography (ECT) is gaining popularity due to its non-invasive nature and its capability to differentiate between different phases based on their permittivity distribution. In recent years, several hardware designs have been provided for ECT systems that have improved its resolution of measurements to be around attofarads (aF, 10(-18) F), or the number of channels, that is required to be large for some applications that require a significant amount of data. In terms of image acquisition time, some recent systems could achieve a throughput of a few hundred frames per second, while data processing time could be achieved in only a few milliseconds per frame. This paper outlines the concept and main features of the most recent front-end and back-end electronic circuits dedicated for ECT systems. In this paper, multiple-excitation capacitance polling, a front-end electronic technique, shows promising results for ECT systems to acquire fast data acquisition speeds. A highly parallel field-programmable gate array (FPGA) based architecture for a fast reconstruction algorithm is also described. This article is part of the themed issue 'Supersensing through industrial process tomography'. © 2016 The Author(s).

Support for Quality Assurance in End-User Systems.

ERIC Educational Resources Information Center

Klepper, Robert; McKenna, Edward G.

1989-01-01

Suggests an approach that organizations can take to provide centralized support services for quality assurance in end-user information systems, based on the experiences of a support group at Citicorp Mortgage, Inc. The functions of the support group include user education, software selection, and assistance in testing, implementation, and support…

Assessment of the effectiveness of head only and back-of-the-head electrical stunning of chickens

PubMed Central

Gibson, T. J.; Taylor, A. H.; Gregory, N. G.

2016-01-01

Abstract The study assesses the effectiveness of reversible head-only and back-of-the-head electrical stunning of chickens using 130–950 mA per bird at 50 Hz AC.Three trials were conducted to compare both stunning systems: (a) behavioural assessment of return of consciousness, (b) insensibility to thermal pain, and (c) assessment of return of brain activity with visually evoked potentials (VEPs).Assessment of behaviour suggested that the period of unconsciousness following head-only electrical stunning was shorter in hens compared to broilers.Stunning across the back-of-the-head delayed the time to return of brainstem function compared to stunning with standard head-only electrodes. Additionally, back-of-the-head stunning produced a more prolonged period of electroanalgesia compared to head-only.Based on examination of return of brain function with VEPs in hens, back-of-the-head stunning produced a shorter-lasting stun than standard head-only. However, even for standard head-only, the stun was notably shorter than previously reported. In some birds, brain function had returned within 9 s after the end of stunning.The results suggest that some birds may recover consciousness prior to or during the neck cut. Based on these findings, back-of-the-head stunning and standard head-only stunning of hens should not be recommended without further development. PMID:27023411

A neural network strategy for end-point optimization of batch processes.

PubMed

Krothapally, M; Palanki, S

1999-01-01

The traditional way of operating batch processes has been to utilize an open-loop "golden recipe". However, there can be substantial batch to batch variation in process conditions and this open-loop strategy can lead to non-optimal operation. In this paper, a new approach is presented for end-point optimization of batch processes by utilizing neural networks. This strategy involves the training of two neural networks; one to predict switching times and the other to predict the input profile in the singular region. This approach alleviates the computational problems associated with the classical Pontryagin's approach and the nonlinear programming approach. The efficacy of this scheme is illustrated via simulation of a fed-batch fermentation.

End-to-end performance analysis using engineering confidence models and a ground processor prototype

NASA Astrophysics Data System (ADS)

Kruse, Klaus-Werner; Sauer, Maximilian; Jäger, Thomas; Herzog, Alexandra; Schmitt, Michael; Huchler, Markus; Wallace, Kotska; Eisinger, Michael; Heliere, Arnaud; Lefebvre, Alain; Maher, Mat; Chang, Mark; Phillips, Tracy; Knight, Steve; de Goeij, Bryan T. G.; van der Knaap, Frits; Van't Hof, Adriaan

2015-10-01

The European Space Agency (ESA) and the Japan Aerospace Exploration Agency (JAXA) are co-operating to develop the EarthCARE satellite mission with the fundamental objective of improving the understanding of the processes involving clouds, aerosols and radiation in the Earth's atmosphere. The EarthCARE Multispectral Imager (MSI) is relatively compact for a space borne imager. As a consequence, the immediate point-spread function (PSF) of the instrument will be mainly determined by the diffraction caused by the relatively small optical aperture. In order to still achieve a high contrast image, de-convolution processing is applied to remove the impact of diffraction on the PSF. A Lucy-Richardson algorithm has been chosen for this purpose. This paper will describe the system setup and the necessary data pre-processing and post-processing steps applied in order to compare the end-to-end image quality with the L1b performance required by the science community.

Spacelab output processing system architectural study

NASA Technical Reports Server (NTRS)

1977-01-01

Two different system architectures are presented. The two architectures are derived from two different data flows within the Spacelab Output Processing System. The major differences between these system architectures are in the position of the decommutation function (the first architecture performs decommutation in the latter half of the system and the second architecture performs that function in the front end of the system). In order to be examined, the system was divided into five stand-alone subsystems; Work Assembler, Mass Storage System, Output Processor, Peripheral Pool, and Resource Monitor. The work load of each subsystem was estimated independent of the specific devices to be used. The candidate devices were surveyed from a wide sampling of off-the-shelf devices. Analytical expressions were developed to quantify the projected workload in conjunction with typical devices which would adequately handle the subsystem tasks. All of the study efforts were then directed toward preparing performance and cost curves for each architecture subsystem.

Water reclamation from shale gas drilling flow-back fluid using a novel forward osmosis-vacuum membrane distillation hybrid system.

PubMed

Li, Xue-Mei; Zhao, Baolong; Wang, Zhouwei; Xie, Ming; Song, Jianfeng; Nghiem, Long D; He, Tao; Yang, Chi; Li, Chunxia; Chen, Gang

2014-01-01

This study examined the performance of a novel hybrid system of forward osmosis (FO) combined with vacuum membrane distillation (VMD) for reclaiming water from shale gas drilling flow-back fluid (SGDF). In the hybrid FO-VMD system, water permeated through the FO membrane into a draw solution reservoir, and the VMD process was used for draw solute recovery and clean water production. Using a SGDF sample obtained from a drilling site in China, the hybrid system could achieve almost 90% water recovery. Quality of the reclaimed water was comparable to that of bottled water. In the hybrid FO-VMD system, FO functions as a pre-treatment step to remove most contaminants and constituents that may foul or scale the membrane distillation (MD) membrane, whereas MD produces high quality water. It is envisioned that the FO-VMD system can recover high quality water not only from SGDF but also other wastewaters with high salinity and complex compositions.

Comparison of Metal-Backed Free-Space and Open-Ended Coaxial Probe Techniques for the Dielectric Characterization of Aeronautical Composites †

PubMed Central

López-Rodríguez, Patricia; Escot-Bocanegra, David; Poyatos-Martínez, David; Weinmann, Frank

2016-01-01

The trend in the last few decades is that current unmanned aerial vehicles are completely made of composite materials rather than metallic, such as carbon-fiber or fiberglass composites. From the electromagnetic point of view, this fact forces engineers and scientists to assess how these materials may affect their radar response or their electronics in terms of electromagnetic compatibility. In order to evaluate this, electromagnetic characterization of different composite materials has become a need. Several techniques exist to perform this characterization, all of them based on the utilization of different sensors for measuring different parameters. In this paper, an implementation of the metal-backed free-space technique, based on the employment of antenna probes, is utilized for the characterization of composite materials that belong to an actual drone. Their extracted properties are compared with those given by a commercial solution, an open-ended coaxial probe (OECP). The discrepancies found between both techniques along with a further evaluation of the methodologies, including measurements with a split-cavity resonator, conclude that the implemented free-space technique provides more reliable results for this kind of composites than the OECP technique. PMID:27347966

Expert system and process optimization techniques for real-time monitoring and control of plasma processes

NASA Astrophysics Data System (ADS)

Cheng, Jie; Qian, Zhaogang; Irani, Keki B.; Etemad, Hossein; Elta, Michael E.

1991-03-01

To meet the ever-increasing demand of the rapidly-growing semiconductor manufacturing industry it is critical to have a comprehensive methodology integrating techniques for process optimization real-time monitoring and adaptive process control. To this end we have accomplished an integrated knowledge-based approach combining latest expert system technology machine learning method and traditional statistical process control (SPC) techniques. This knowledge-based approach is advantageous in that it makes it possible for the task of process optimization and adaptive control to be performed consistently and predictably. Furthermore this approach can be used to construct high-level and qualitative description of processes and thus make the process behavior easy to monitor predict and control. Two software packages RIST (Rule Induction and Statistical Testing) and KARSM (Knowledge Acquisition from Response Surface Methodology) have been developed and incorporated with two commercially available packages G2 (real-time expert system) and ULTRAMAX (a tool for sequential process optimization).

Improved interoceptive awareness in chronic low back pain: a comparison of Back school versus Feldenkrais method.

PubMed

Paolucci, Teresa; Zangrando, Federico; Iosa, Marco; De Angelis, Simona; Marzoli, Caterina; Piccinini, Giulia; Saraceni, Vincenzo Maria

2017-05-01

To determine the efficacy of the Feldenkrais method for relieving pain in patients with chronic low back pain (CLBP) and the improvement of interoceptive awareness. This study was designed as a single-blind randomized controlled trial. Fifty-three patients with a diagnosis of CLBP for at least 3 months were randomly allocated to the Feldenkrais (mean age 61.21 ± 11.53 years) or Back School group (mean age 60.70 ± 11.72 years). Pain was assessed using the visual analog scale (VAS) and McGill Pain Questionnaire (MPQ), disability was evaluated with the Waddel Disability Index, quality of life was measured with the Short Form-36 Health Survey (SF-36), and mind-body interactions were studied using the Multidimensional Assessment of Interoceptive Awareness Questionnaire (MAIA). Data were collected at baseline, at the end of treatment, and at the 3-month follow-up. The two groups were matched at baseline for all the computed parameters. At the end of treatment (Tend), there were no significant differences between groups regarding chronic pain reduction (p = 0.290); VAS and MAIA-N sub scores correlated at Tend (R = 0.296, p = 0.037). By the Friedman analysis, both groups experienced significant changes in pain (p < 0.001) and disability (p < 0.001) along the investigated period. The Feldenkrais method has comparable efficacy as Back School in CLBP. Implications for rehabilitation The Feldenkrais method is a mind-body therapy that is based on awareness through movement lessons, which are verbally guided explorations of movement that are conducted by a physiotherapist who is experienced and trained in this method. It aims to increase self-awareness, expand a person's repertoire of movements, and to promote increased functioning in contexts in which the entire body cooperates in the execution of movements. Interoceptive awareness, which improves with rehabilitation, has a complex function in the perception of chronic pain and should be

The development and prospects of the end-of-life vehicle recycling system in Taiwan.

PubMed

Chen, Kuan-chung; Huang, Shih-han; Lian, I-wei

2010-01-01

Automobiles usually contain toxic substances, such as lubricants, acid solutions and coolants. Therefore, inappropriate handling of end-of-life vehicles (ELVs) will result in environmental pollution. ELV parts, which include metallic and non-metallic substances, are increasingly gaining recycling value due to the recent global shortage of raw materials. Hence, the establishment of a proper recycling system for ELVs will not only reduce the impact on the environment during the recycling process, but it will also facilitate the effective reuse of recycled resources. Prior to 1994, the recycling of ELVs in Taiwan was performed by related operators in the industry. Since the publishing of the "End-of-life vehicle recycling guidelines" under the authority of the Waste Disposal Act by the Environmental Protection Administration (EPA) in 1994, the recycling of ELVs in Taiwan has gradually become systematic. Subsequently, the Recycling Fund Management Board (RFMB) of the EPA was established in 1998 to collect a Collection-Disposal-Treatment Fee (recycling fee) from responsible enterprises for recycling and related tasks. Since then, the recycling channels, processing equipment, and techniques for ELVs in Taiwan have gradually become established. This paper reviews the establishment of the ELV recycling system, analyzes the current system and its performance, and provides some recommendations for future development. The reduction of auto shredder residue (ASR) is a key factor in maximizing the resource recovery rate and recycling efficiency. The RFMB needs to provide strong economic incentives to further increase the recycling rate and to encourage the automobile industry to design and market greener cars. 2010 Elsevier Ltd. All rights reserved.

Implementation of a process analytical technology system in a freeze-drying process using Raman spectroscopy for in-line process monitoring.

PubMed

De Beer, T R M; Allesø, M; Goethals, F; Coppens, A; Heyden, Y Vander; De Diego, H Lopez; Rantanen, J; Verpoort, F; Vervaet, C; Remon, J P; Baeyens, W R G

2007-11-01

The aim of the present study was to propose a strategy for the implementation of a Process Analytical Technology system in freeze-drying processes. Mannitol solutions, some of them supplied with NaCl, were used as models to freeze-dry. Noninvasive and in-line Raman measurements were continuously performed during lyophilization of the solutions to monitor real time the mannitol solid state, the end points of the different process steps (freezing, primary drying, secondary drying), and physical phenomena occurring during the process. At-line near-infrared (NIR) and X-ray powder diffractometry (XRPD) measurements were done to confirm the Raman conclusions and to find out additional information. The collected spectra during the processes were analyzed using principal component analysis and multivariate curve resolution. A two-level full factorial design was used to study the significant influence of process (freezing rate) and formulation variables (concentration of mannitol, concentration of NaCl, volume of freeze-dried sample) upon freeze-drying. Raman spectroscopy was able to monitor (i) the mannitol solid state (amorphous, alpha, beta, delta, and hemihydrate), (ii) several process step end points (end of mannitol crystallization during freezing, primary drying), and (iii) physical phenomena occurring during freeze-drying (onset of ice nucleation, onset of mannitol crystallization during the freezing step, onset of ice sublimation). NIR proved to be a more sensitive tool to monitor sublimation than Raman spectroscopy, while XRPD helped to unravel the mannitol hemihydrate in the samples. The experimental design results showed that several process and formulation variables significantly influence different aspects of lyophilization and that both are interrelated. Raman spectroscopy (in-line) and NIR spectroscopy and XRPD (at-line) not only allowed the real-time monitoring of mannitol freeze-drying processes but also helped (in combination with experimental design) us

Countercurrent direct contact heat exchange process and system

DOEpatents

Wahl, III, Edward F.; Boucher, Frederic B.

1979-01-01

Recovery of energy from geothermal brines and other hot water sources by direct contact heat exchange with a working fluid, such as a hydrocarbon working fluid, e.g. isobutane. The process and system consists of a plurality of stages, each stage including mixing and settling units. In the first stage, hot brine and arm working fluid are intimately mixed and passed into a settler wherein the brine settles to the bottom of the settler and the hot working fluid rises to the top. The hot working fluid is passed to a heat engine or turbine to produce work and the working fluid is then recycled back into the system. The system is comprised of a series of stages each containing a settler and mixer, and wherein the working fluid and the brine flow in a countercurrent manner through the stages to recover the heat from the brine in increments and raise the temperature of the working fluid in increments.

System safety management lessons learned from the US Army acquisition process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piatt, J.A.

1989-05-01

The Assistant Secretary of the Army for Research, Development and Acquisition directed the Army Safety Center to provide an audit of the causes of accidents and safety of use restrictions on recently fielded systems by tracking residual hazards back through the acquisition process. The objective was to develop lessons learned'' that could be applied to the acquisition process to minimize mishaps in fielded systems. System safety management lessons learned are defined as Army practices or policies, derived from past successes and failures, that are expected to be effective in eliminating or reducing specific systemic causes of residual hazards. They aremore » broadly applicable and supportive of the Army structure and acquisition objectives. Pacific Northwest Laboratory (PNL) was given the task of conducting an independent, objective appraisal of the Army's system safety program in the context of the Army materiel acquisition process by focusing on four fielded systems which are products of that process. These systems included the Apache helicopter, the Bradley Fighting Vehicle (BFV), the Tube Launched, Optically Tracked, Wire Guided (TOW) Missile and the High Mobility Multipurpose Wheeled Vehicle (HMMWV). The objective of this study was to develop system safety management lessons learned associated with the acquisition process. The first step was to identify residual hazards associated with the selected systems. Since it was impossible to track all residual hazards through the acquisition process, certain well-known, high visibility hazards were selected for detailed tracking. These residual hazards illustrate a variety of systemic problems. Systemic or process causes were identified for each residual hazard and analyzed to determine why they exist. System safety management lessons learned were developed to address related systemic causal factors. 29 refs., 5 figs.« less

Efficient audio signal processing for embedded systems

NASA Astrophysics Data System (ADS)

Chiu, Leung Kin

As mobile platforms continue to pack on more computational power, electronics manufacturers start to differentiate their products by enhancing the audio features. However, consumers also demand smaller devices that could operate for longer time, hence imposing design constraints. In this research, we investigate two design strategies that would allow us to efficiently process audio signals on embedded systems such as mobile phones and portable electronics. In the first strategy, we exploit properties of the human auditory system to process audio signals. We designed a sound enhancement algorithm to make piezoelectric loudspeakers sound ”richer" and "fuller." Piezoelectric speakers have a small form factor but exhibit poor response in the low-frequency region. In the algorithm, we combine psychoacoustic bass extension and dynamic range compression to improve the perceived bass coming out from the tiny speakers. We also developed an audio energy reduction algorithm for loudspeaker power management. The perceptually transparent algorithm extends the battery life of mobile devices and prevents thermal damage in speakers. This method is similar to audio compression algorithms, which encode audio signals in such a ways that the compression artifacts are not easily perceivable. Instead of reducing the storage space, however, we suppress the audio contents that are below the hearing threshold, therefore reducing the signal energy. In the second strategy, we use low-power analog circuits to process the signal before digitizing it. We designed an analog front-end for sound detection and implemented it on a field programmable analog array (FPAA). The system is an example of an analog-to-information converter. The sound classifier front-end can be used in a wide range of applications because programmable floating-gate transistors are employed to store classifier weights. Moreover, we incorporated a feature selection algorithm to simplify the analog front-end. A machine

End-use quality of soft kernel durum wheat

USDA-ARS?s Scientific Manuscript database

Kernel texture is a major determinant of end-use quality of wheat. Durum wheat has very hard kernels. We developed soft kernel durum wheat via Ph1b-mediated homoeologous recombination. The Hardness locus was transferred from Chinese Spring to Svevo durum wheat via back-crossing. ‘Soft Svevo’ had SKC...

Efficacy of transverse tripolar spinal cord stimulator for the relief of chronic low back pain from failed back surgery.

PubMed

Buvanendran, Asokumar; Lubenow, Timothy J

2008-01-01

Failed back surgery syndrome is a common clinical entity for which spinal cord stimulation has been found to be an effective mode of analgesia, but with variable success rates. To determine if focal stimulation of the dorsal columns with a transverse tripolar lead might achieve deeper penetration of the electrical stimulus into the spinal cord and therefore provide greater analgesia to the back. Case report. We describe a 42-year-old female with failed back surgery syndrome that had greater back pain than leg pain. The tripolar lead configuration was achieved by placing percutaneously an octapolar lead in the spinal midline followed by 2 adjacent quadripolar leads, advanced to the T7-T10 vertebral bodies. Tripolar stimulation pattern resulted in more than 70% pain relief in this patient during the screening trial, while stimulation of one or 2 electrodes only provided 20% pain relief. After implantation of a permanent tripolar electrode system with a single rechargeable battery, the pain relief was maintained for one year. This is case report describing a case of a patient with chronic low back pain with a diagnosis of failed back surgery syndrome in which transverse tripolar stimulation using an octapolar and 2 quadripolar leads appeared to be beneficial. The transverse tripolar system consists of a central cathode surrounded by anodes, using 3 leads. This arrangement may contribute to maximum dorsal column stimulation with minimal dorsal root stimulation and provide analgesia to the lower back.

Tag ID Subdivision Scheme for Efficient Authentication and Security-Enhancement of RFID System in USN

NASA Astrophysics Data System (ADS)

Lee, Kijeong; Park, Byungjoo; Park, Gil-Cheol

Radio frequency identification (RFID) is a generic term that is used to describe a system that transmits the identity (in the form of a unique serial number) of an object or person wirelessly, using radio waves. However, there are security threats in the RFID system related to its technical components. For example, illegal RFID tag readers can read tag ID and recognize most RFID Readers, a security threat that needs in-depth attention. Previous studies show some ideas on how to minimize these security threats like studying the security protocols between tag, reader and Back-end DB. In this research, the team proposes an RFID Tag ID Subdivision Scheme to authenticate the permitted tag only in USN (Ubiquitous Sensor Network). Using the proposed scheme, the Back-end DB authenticates selected tags only to minimize security threats like eavesdropping and decreasing traffic in Back-end DB.

GaAs High Breakdown Voltage Front and Back Side Processed Schottky Detectors for X-Ray Detection

DTIC Science & Technology

2007-11-01

front and back side processed, unintentionally doped bulk gallium -arsenic (GaAs) Schottky detectors and determined that GaAs detectors with a large...a few materials that fulfill these requirements are gallium -arsenic (GaAs) and cadmium-zinc-tellurium (CdZnTe or CZT). They are viable alternative...Whitehill, C.; Pospíšil, S.; Wilhem, I.; Doležal, Z.; Juergensen, H.; Heuken, M. Development of low-pressure vapour -phase epitaxial GaAs for medical imaging

The postoperative COFAS end-stage ankle arthritis classification system: interobserver and intraobserver reliability.

PubMed

Krause, Fabian G; Di Silvestro, Matthew; Penner, Murray J; Wing, Kevin J; Glazebrook, Mark A; Daniels, Timothy R; Lau, Johnny T C; Younger, Alastair S E

2012-02-01

End-stage ankle arthritis is operatively treated with numerous designs of total ankle replacement and different techniques for ankle fusion. For superior comparison of these procedures, outcome research requires a classification system to stratify patients appropriately. A postoperative 4-type classification system was designed by 6 fellowship-trained foot and ankle surgeons. Four surgeons reviewed blinded patient profiles and radiographs on 2 occasions to determine the interobserver and intraobserver reliability of the classification. Excellent interobserver reliability (κ = .89) and intraobserver reproducibility (κ = .87) were demonstrated for the postoperative classification system. In conclusion, the postoperative Canadian Orthopaedic Foot and Ankle Society (COFAS) end-stage ankle arthritis classification system appears to be a valid tool to evaluate the outcome of patients operated for end-stage ankle arthritis.

A real-time 3D end-to-end augmented reality system (and its representation transformations)

NASA Astrophysics Data System (ADS)

Tytgat, Donny; Aerts, Maarten; De Busser, Jeroen; Lievens, Sammy; Rondao Alface, Patrice; Macq, Jean-Francois

2016-09-01

The new generation of HMDs coming to the market is expected to enable many new applications that allow free viewpoint experiences with captured video objects. Current applications usually rely on 3D content that is manually created or captured in an offline manner. In contrast, this paper focuses on augmented reality applications that use live captured 3D objects while maintaining free viewpoint interaction. We present a system that allows live dynamic 3D objects (e.g. a person who is talking) to be captured in real-time. Real-time performance is achieved by traversing a number of representation formats and exploiting their specific benefits. For instance, depth images are maintained for fast neighborhood retrieval and occlusion determination, while implicit surfaces are used to facilitate multi-source aggregation for both geometry and texture. The result is a 3D reconstruction system that outputs multi-textured triangle meshes at real-time rates. An end-to-end system is presented that captures and reconstructs live 3D data and allows for this data to be used on a networked (AR) device. For allocating the different functional blocks onto the available physical devices, a number of alternatives are proposed considering the available computational power and bandwidth for each of the components. As we will show, the representation format can play an important role in this functional allocation and allows for a flexible system that can support a highly heterogeneous infrastructure.

Habitat relationships of eastern red-backed salamanders (Plethodon cinereus) in Appalachian agroforestry and grazing systems

Treesearch

Breanna L. Riedel; Kevin R. Russell; W. Mark Ford; Katherine P. O' Neill; Harry W. Godwin

2008-01-01

Woodland salamander responses to either traditional grazing or silvopasture systems are virtually unknown. An information-theoretic modelling approach was used to evaluate responses of red-backed salamanders (Plethodon cinereus) to silvopasture and meadow conversions in southern West Virginia. Searches of area-constrained plots and artificial...

End-to-end modeling as part of an integrated research program in the Bering Sea

NASA Astrophysics Data System (ADS)

Punt, André E.; Ortiz, Ivonne; Aydin, Kerim Y.; Hunt, George L.; Wiese, Francis K.

2016-12-01

Traditionally, the advice provided to fishery managers has focused on the trade-offs between short- and long-term yields, and between future resource size and expected future catches. The harvest control rules that are used to provide management advice consequently relate catches to stock biomass levels expressed relative to reference biomass levels. There are, however, additional trade-offs. Ecosystem-based fisheries management (EBFM) aims to consider fish and fisheries in their ecological context, taking into account physical, biological, economic, and social factors. However, making EBFM operational remains challenging. It is generally recognized that end-to-end modeling should be a key part of implementing EBFM, along with harvest control rules that use information in addition to estimates of stock biomass to provide recommendations for management actions. Here we outline the process for selecting among alternative management strategies in an ecosystem context and summarize a Field-integrated End-To-End modeling program, or FETE, intended to implement this process as part of the Bering Sea Project. A key aspect of this project was that, from the start, the FETE included a management strategy evaluation component to compare management strategies. Effective use of end-to-end modeling requires that the models developed for a system are indeed integrated across climate drivers, lower trophic levels, fish population dynamics, and fisheries and their management. We summarize the steps taken by the program managers to promote integration of modeling efforts by multiple investigators and highlight the lessons learned during the project that can be used to guide future use and design of end-to-end models.

Design participation as an insurance: risk-management and end-user participation in the development of information systems in healthcare organizations.

PubMed

Vimarlund, V; Timpka, T

2002-01-01

The aim of this paper is to build a theoretical framework for analysis of when decision-makers should use end-user participation as a form of insurance for unforeseen consequences of implementing information systems in healthcare organizations. Data were collected in a case study of an information system development project in a small clinical setting. During the initial phase, the future end-users of the system were allowed to actively influence the system design and test every new tool that was considered for implementation. The results of the case study suggest that when time and effort are invested in allowing healthcare staff to participate in information system development processes, the benefits can well exceed the costs throughout the life cycle of the project. Risk-averse decision-makers fearing negative secondary consequences of a HIS, with regard to clinical work flow, will always adopt measures to prevent future failures, if they can find a possibility of shifting these risks. Therefore, they calculate the present discounted value of the effects accrued over time to the unit and predict the amount of resources they are willing to pay to acquire on insurance (such as design participation) that will protect the organization from future losses. End-user participation in the design process can be the key positive influence on the quality of the service and, thereby, organizational effectiveness. Investments in broad design participation can, consequently, be a productive activity that transforms potential current income into future benefits.

End-to-End ASR-Free Keyword Search From Speech

NASA Astrophysics Data System (ADS)

Audhkhasi, Kartik; Rosenberg, Andrew; Sethy, Abhinav; Ramabhadran, Bhuvana; Kingsbury, Brian

2017-12-01

End-to-end (E2E) systems have achieved competitive results compared to conventional hybrid hidden Markov model (HMM)-deep neural network based automatic speech recognition (ASR) systems. Such E2E systems are attractive due to the lack of dependence on alignments between input acoustic and output grapheme or HMM state sequence during training. This paper explores the design of an ASR-free end-to-end system for text query-based keyword search (KWS) from speech trained with minimal supervision. Our E2E KWS system consists of three sub-systems. The first sub-system is a recurrent neural network (RNN)-based acoustic auto-encoder trained to reconstruct the audio through a finite-dimensional representation. The second sub-system is a character-level RNN language model using embeddings learned from a convolutional neural network. Since the acoustic and text query embeddings occupy different representation spaces, they are input to a third feed-forward neural network that predicts whether the query occurs in the acoustic utterance or not. This E2E ASR-free KWS system performs respectably despite lacking a conventional ASR system and trains much faster.

Back pain is associated with changes in loading pattern throughout forward and backward bending.

PubMed

Shum, Gary L K; Crosbie, Jack; Lee, Raymond Y W

2010-12-01

Experimental study to determine the kinetics of the lumbar spine (LS) and hips during forward and backward bending. To investigate the effects of back pain, with and without a positive straight leg raise (SLR) sign, on the loading patterns in the LS and hip during forward and backward bending. Forward and backward bending are important components of many functional activities and are part of routine clinical examination. However, there is a little information about the loading patterns during forward and backward bending in people with back pain with or without a positive SLR sign. Twenty asymptomatic participants, 20 back pain participants, and 20 participants with back pain and a positive SLR sign performed 3 continuous cycles of forward and backward bending. Electromagnetic sensors were attached to body segments to measure their kinematics while 2 nonconductive force plates gathered ground reaction force data. A biomechanical model was used to determine the loading pattern in LS and hips. Although the loading on the LS at the end of the range decreased significantly, the loading at the early and middle ranges of forward bending actually increased significantly in people with back pain, especially in those with positive SLR sign. This suggests that resistance to movement is significantly increased in people with back pain during this movement. This study suggested that it is not sufficient to study the spine at the end of range only, but a complete description of the loading patterns throughout the range is required. Although the maximum range of motion of the spine is reduced in people with back pain, there is a significant increase in the moment acting through the range, particularly in those with a positive SLR sign.

Analysis of Accuracy and Epoch on Back-propagation BFGS Quasi-Newton

NASA Astrophysics Data System (ADS)

Silaban, Herlan; Zarlis, Muhammad; Sawaluddin

2017-12-01

Back-propagation is one of the learning algorithms on artificial neural networks that have been widely used to solve various problems, such as pattern recognition, prediction and classification. The Back-propagation architecture will affect the outcome of learning processed. BFGS Quasi-Newton is one of the functions that can be used to change the weight of back-propagation. This research tested some back-propagation architectures using classical back-propagation and back-propagation with BFGS. There are 7 architectures that have been tested on glass dataset with various numbers of neurons, 6 architectures with 1 hidden layer and 1 architecture with 2 hidden layers. BP with BFGS improves the convergence of the learning process. The average improvement convergence is 98.34%. BP with BFGS is more optimal on architectures with smaller number of neurons with decreased epoch number is 94.37% with the increase of accuracy about 0.5%.

Virtual Systems Pharmacology (ViSP) software for simulation from mechanistic systems-level models.

PubMed

Ermakov, Sergey; Forster, Peter; Pagidala, Jyotsna; Miladinov, Marko; Wang, Albert; Baillie, Rebecca; Bartlett, Derek; Reed, Mike; Leil, Tarek A

2014-01-01

Multiple software programs are available for designing and running large scale system-level pharmacology models used in the drug development process. Depending on the problem, scientists may be forced to use several modeling tools that could increase model development time, IT costs and so on. Therefore, it is desirable to have a single platform that allows setting up and running large-scale simulations for the models that have been developed with different modeling tools. We developed a workflow and a software platform in which a model file is compiled into a self-contained executable that is no longer dependent on the software that was used to create the model. At the same time the full model specifics is preserved by presenting all model parameters as input parameters for the executable. This platform was implemented as a model agnostic, therapeutic area agnostic and web-based application with a database back-end that can be used to configure, manage and execute large-scale simulations for multiple models by multiple users. The user interface is designed to be easily configurable to reflect the specifics of the model and the user's particular needs and the back-end database has been implemented to store and manage all aspects of the systems, such as Models, Virtual Patients, User Interface Settings, and Results. The platform can be adapted and deployed on an existing cluster or cloud computing environment. Its use was demonstrated with a metabolic disease systems pharmacology model that simulates the effects of two antidiabetic drugs, metformin and fasiglifam, in type 2 diabetes mellitus patients.

Virtual Systems Pharmacology (ViSP) software for simulation from mechanistic systems-level models

PubMed Central

Ermakov, Sergey; Forster, Peter; Pagidala, Jyotsna; Miladinov, Marko; Wang, Albert; Baillie, Rebecca; Bartlett, Derek; Reed, Mike; Leil, Tarek A.

2014-01-01

Multiple software programs are available for designing and running large scale system-level pharmacology models used in the drug development process. Depending on the problem, scientists may be forced to use several modeling tools that could increase model development time, IT costs and so on. Therefore, it is desirable to have a single platform that allows setting up and running large-scale simulations for the models that have been developed with different modeling tools. We developed a workflow and a software platform in which a model file is compiled into a self-contained executable that is no longer dependent on the software that was used to create the model. At the same time the full model specifics is preserved by presenting all model parameters as input parameters for the executable. This platform was implemented as a model agnostic, therapeutic area agnostic and web-based application with a database back-end that can be used to configure, manage and execute large-scale simulations for multiple models by multiple users. The user interface is designed to be easily configurable to reflect the specifics of the model and the user's particular needs and the back-end database has been implemented to store and manage all aspects of the systems, such as Models, Virtual Patients, User Interface Settings, and Results. The platform can be adapted and deployed on an existing cluster or cloud computing environment. Its use was demonstrated with a metabolic disease systems pharmacology model that simulates the effects of two antidiabetic drugs, metformin and fasiglifam, in type 2 diabetes mellitus patients. PMID:25374542

Increased integrity of white matter pathways after dual n-back training.

PubMed

Salminen, Tiina; Mårtensson, Johan; Schubert, Torsten; Kühn, Simone

2016-06-01

Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single n-back training because of the involvement of two modalities and the additional dual-task coordination component of the task. The dual n-back training group showed increased white matter integrity (reflected as increased fractional anisotropy, FA) after training. The effects were mostly left lateralized as compared with changes from pretest to posttest in the passive and active control groups. Additionally, significant effects were observed in the anterior part of the corpus callosum, when the training group was compared with the passive control group. There were no changes in pretest to posttest FA changes between the passive and active control groups. The results therefore show that dual n-back training produces increased integrity in white matter pathways connecting different brain regions. The results are discussed in reference to the bi-modal dual-task component of the training task. Copyright © 2016 Elsevier Inc. All rights reserved.

Investigation on Effect of Material Hardness in High Speed CNC End Milling Process.

PubMed

Dhandapani, N V; Thangarasu, V S; Sureshkannan, G

2015-01-01

This research paper analyzes the effects of material properties on surface roughness, material removal rate, and tool wear on high speed CNC end milling process with various ferrous and nonferrous materials. The challenge of material specific decision on the process parameters of spindle speed, feed rate, depth of cut, coolant flow rate, cutting tool material, and type of coating for the cutting tool for required quality and quantity of production is addressed. Generally, decision made by the operator on floor is based on suggested values of the tool manufacturer or by trial and error method. This paper describes effect of various parameters on the surface roughness characteristics of the precision machining part. The prediction method suggested is based on various experimental analysis of parameters in different compositions of input conditions which would benefit the industry on standardization of high speed CNC end milling processes. The results show a basis for selection of parameters to get better results of surface roughness values as predicted by the case study results.

Investigation on Effect of Material Hardness in High Speed CNC End Milling Process

PubMed Central

Dhandapani, N. V.; Thangarasu, V. S.; Sureshkannan, G.

2015-01-01

This research paper analyzes the effects of material properties on surface roughness, material removal rate, and tool wear on high speed CNC end milling process with various ferrous and nonferrous materials. The challenge of material specific decision on the process parameters of spindle speed, feed rate, depth of cut, coolant flow rate, cutting tool material, and type of coating for the cutting tool for required quality and quantity of production is addressed. Generally, decision made by the operator on floor is based on suggested values of the tool manufacturer or by trial and error method. This paper describes effect of various parameters on the surface roughness characteristics of the precision machining part. The prediction method suggested is based on various experimental analysis of parameters in different compositions of input conditions which would benefit the industry on standardization of high speed CNC end milling processes. The results show a basis for selection of parameters to get better results of surface roughness values as predicted by the case study results. PMID:26881267

RPA coordinates DNA end resection and prevents formation of DNA hairpins.

PubMed

Chen, Huan; Lisby, Michael; Symington, Lorraine S

2013-05-23

Replication protein A (RPA) is an essential eukaryotic single-stranded DNA binding protein with a central role in DNA metabolism. RPA directly participates in DNA double-strand break repair by stimulating 5'-3' end resection by the Sgs1/BLM helicase and Dna2 endonuclease in vitro. Here we investigated the role of RPA in end resection in vivo, using a heat-inducible degron system that allows rapid conditional depletion of RPA in Saccharomyces cerevisiae. We found that RPA depletion eliminated both the Sgs1-Dna2- and Exo1-dependent extensive resection pathways and synergized with mre11Δ to prevent end resection. The short single-stranded DNA tails formed in the absence of RPA were unstable due to 3' strand loss and the formation of fold-back hairpin structures that required resection initiation and Pol32-dependent DNA synthesis. Thus, RPA is required to generate ssDNA, and also to protect ssDNA from degradation and inappropriate annealing that could lead to genome rearrangements. Copyright © 2013 Elsevier Inc. All rights reserved.

End-to-end simulation and verification of GNC and robotic systems considering both space segment and ground segment

NASA Astrophysics Data System (ADS)

Benninghoff, Heike; Rems, Florian; Risse, Eicke; Brunner, Bernhard; Stelzer, Martin; Krenn, Rainer; Reiner, Matthias; Stangl, Christian; Gnat, Marcin

2018-01-01

In the framework of a project called on-orbit servicing end-to-end simulation, the final approach and capture of a tumbling client satellite in an on-orbit servicing mission are simulated. The necessary components are developed and the entire end-to-end chain is tested and verified. This involves both on-board and on-ground systems. The space segment comprises a passive client satellite, and an active service satellite with its rendezvous and berthing payload. The space segment is simulated using a software satellite simulator and two robotic, hardware-in-the-loop test beds, the European Proximity Operations Simulator (EPOS) 2.0 and the OOS-Sim. The ground segment is established as for a real servicing mission, such that realistic operations can be performed from the different consoles in the control room. During the simulation of the telerobotic operation, it is important to provide a realistic communication environment with different parameters like they occur in the real world (realistic delay and jitter, for example).

Structured back gates for high-mobility two-dimensional electron systems using oxygen ion implantation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berl, M., E-mail: mberl@phys.ethz.ch; Tiemann, L.; Dietsche, W.

2016-03-28

We present a reliable method to obtain patterned back gates compatible with high mobility molecular beam epitaxy via local oxygen ion implantation that suppresses the conductivity of an 80 nm thick silicon doped GaAs epilayer. Our technique was optimized to circumvent several constraints of other gating and implantation methods. The ion-implanted surface remains atomically flat which allows unperturbed epitaxial overgrowth. We demonstrate the practical application of this gating technique by using magneto-transport spectroscopy on a two-dimensional electron system (2DES) with a mobility exceeding 20 × 10{sup 6} cm{sup 2}/V s. The back gate was spatially separated from the Ohmic contacts of the 2DES,more » thus minimizing the probability for electrical shorts or leakage and permitting simple contacting schemes.« less

Kinematics Analysis of End Effector for Carrier Robot of Feeding Broiler Chicken System

NASA Astrophysics Data System (ADS)

Syam, Rafiuddin; Arsyad, Hairul; Bauna, Ruslan; Renreng, Ilyas; Bakhri, Syaiful

2018-02-01

The demand for commodities, especially Broiler chicken farms are increasing, the volume of feed requirements Broiler chickens increased with age up to the age of 30-57 days required feed 3,829 grams/day/head, so if the chicken population is 3,000 needed transporting feed 11 487 kg/day, This research aims to produce a robot capable of transporting feed in the top of the cage by using a control system so as to make efficient use of manpower. Design robot performed using software design three-dimensional Solidworks2010, process of making the robot is started with the design manufacture three (3) units of mechanical systems (mechanical system for holder feed, mechanical systems for lifter feed and mechanical systems for transporting feed), then do the design process framework as a component buffer so that the mechanical system will work properly and safely when the robot operates. Furthermore, the manufacture of electronic circuits and control are using Arduino Mega microcontroller. After assembling all components mechanical systems and installation of electronic systems and control, then experiments to evaluate the performance of the robot have been made. The results of experiments showed that all components work well according to plan, in particular the speed and acceleration of end effector motion so it can hold and release the feed well. This strongly supports the robots perform tasks in accordance with the intent, i.e., holding, lifting and moving feed.

Electronic Nicotine Delivery Systems (ENDS): What Nurses Need to Know.

PubMed

Essenmacher, Carol; Naegle, Madeline; Baird, Carolyn; Vest, Bridgette; Spielmann, Rene; Smith-East, Marie; Powers, Leigh

Efforts to decrease adverse effects of tobacco use are affected by emergence of new nicotine delivery products. Advertising, product promotion, and social media promote use of these products, yet a lack of evidence regarding safety leaves nurses unprepared to counsel patients. To critically evaluate current research, reviews of literature, expert opinion, and stakeholder policy proposals on use and safety of electronic nicotine delivery systems (ENDS). A targeted examination of literature generated by key stakeholders and subject matter experts was conducted using key words, modified by risk factors, and limited to the past 8 years. Current knowledge gaps in research literature and practice implications of the literature are discussed. The safety of ENDS is questionable and unclear. There are clear health risks of nicotine exposure to developing brains. Potential health risks of ENDS secondhand emissions exposure exist. Using ENDS to facilitate total tobacco cessation is not proven.

Interchangeable whole-body and nose-only exposure system

DOEpatents

Cannon, W.C.; Allemann, R.T.; Moss, O.R.; Decker, J.R. Jr.

1992-03-31

An exposure system for experimental animals includes a container for a single animal which has a double wall. The animal is confined within the inner wall. Gaseous material enters a first end, flows over the entire animal, then back between the walls and out the first end. The system also includes an arrangement of valve-controlled manifolds for supplying gaseous material to, and exhausting it from, the containers. 6 figs.

Interchangeable whole-body and nose-only exposure system

DOEpatents

Cannon, William C.; Allemann, Rudolph T.; Moss, Owen R.; Decker, Jr., John R.

1992-01-01

An exposure system for experimental animals includes a container for a single animal which has a double wall. The animal is confined within the inner wall. Gaseous material enters a first end, flows over the entire animal, then back between the walls and out the first end. The system also includes an arrangement of valve-controlled manifolds for supplying gaseous material to, and exhausting it from, the containers.

Implementation of a Multimodal Mobile System for Point-of-Sale Surveillance: Lessons Learned From Case Studies in Washington, DC, and New York City.

PubMed

Cantrell, Jennifer; Ganz, Ollie; Ilakkuvan, Vinu; Tacelosky, Michael; Kreslake, Jennifer; Moon-Howard, Joyce; Aidala, Angela; Vallone, Donna; Anesetti-Rothermel, Andrew; Kirchner, Thomas R

2015-01-01

In tobacco control and other fields, point-of-sale surveillance of the retail environment is critical for understanding industry marketing of products and informing public health practice. Innovations in mobile technology can improve existing, paper-based surveillance methods, yet few studies describe in detail how to operationalize the use of technology in public health surveillance. The aims of this paper are to share implementation strategies and lessons learned from 2 tobacco, point-of-sale surveillance projects to inform and prepare public health researchers and practitioners to implement new mobile technologies in retail point-of-sale surveillance systems. From 2011 to 2013, 2 point-of-sale surveillance pilot projects were conducted in Washington, DC, and New York, New York, to capture information about the tobacco retail environment and test the feasibility of a multimodal mobile data collection system, which included capabilities for audio or video recording data, electronic photographs, electronic location data, and a centralized back-end server and dashboard. We established a preimplementation field testing process for both projects, which involved a series of rapid and iterative tests to inform decisions and establish protocols around key components of the project. Important components of field testing included choosing a mobile phone that met project criteria, establishing an efficient workflow and accessible user interfaces for each component of the system, training and providing technical support to fieldworkers, and developing processes to integrate data from multiple sources into back-end systems that can be utilized in real-time. A well-planned implementation process is critical for successful use and performance of multimodal mobile surveillance systems. Guidelines for implementation include (1) the need to establish and allow time for an iterative testing framework for resolving technical and logistical challenges; (2) developing a streamlined

Implementation of a Multimodal Mobile System for Point-of-Sale Surveillance: Lessons Learned From Case Studies in Washington, DC, and New York City

PubMed Central

Ganz, Ollie; Ilakkuvan, Vinu; Tacelosky, Michael; Kreslake, Jennifer; Moon-Howard, Joyce; Aidala, Angela; Vallone, Donna; Anesetti-Rothermel, Andrew; Kirchner, Thomas R

2015-01-01

Background In tobacco control and other fields, point-of-sale surveillance of the retail environment is critical for understanding industry marketing of products and informing public health practice. Innovations in mobile technology can improve existing, paper-based surveillance methods, yet few studies describe in detail how to operationalize the use of technology in public health surveillance. Objective The aims of this paper are to share implementation strategies and lessons learned from 2 tobacco, point-of-sale surveillance projects to inform and prepare public health researchers and practitioners to implement new mobile technologies in retail point-of-sale surveillance systems. Methods From 2011 to 2013, 2 point-of-sale surveillance pilot projects were conducted in Washington, DC, and New York, New York, to capture information about the tobacco retail environment and test the feasibility of a multimodal mobile data collection system, which included capabilities for audio or video recording data, electronic photographs, electronic location data, and a centralized back-end server and dashboard. We established a preimplementation field testing process for both projects, which involved a series of rapid and iterative tests to inform decisions and establish protocols around key components of the project. Results Important components of field testing included choosing a mobile phone that met project criteria, establishing an efficient workflow and accessible user interfaces for each component of the system, training and providing technical support to fieldworkers, and developing processes to integrate data from multiple sources into back-end systems that can be utilized in real-time. Conclusions A well-planned implementation process is critical for successful use and performance of multimodal mobile surveillance systems. Guidelines for implementation include (1) the need to establish and allow time for an iterative testing framework for resolving technical and

Exposure to hazardous volatile pollutants back diffusing from automobile exhaust systems.

PubMed

Rahman, Md Mahmudur; Kim, Ki-Hyun

2012-11-30

As back diffusion gases from automobiles are significant sources of in-vehicular pollution, we investigated eight automobiles, five for back diffusion (driving) measurements and three for reference conditions (non-driving). To characterize the back diffusion emission conditions, seven volatile organic compounds (VOC) and four carbonyl compounds (CCs) were measured along with dilution-to-threshold (D/T) ratio. The data obtained from back diffusion measurements were examined after having been divided into three subcategories: (i) driving and non-driving, (ii) with and without automobile upgrading (sealing the inner line), and (iii) differences in CO emission levels. Among the VOCs, the concentrations of toluene (T) was found to be the highest (range: 13.6-155 ppb), while benzene (0.19-1.47 ppb) was hardly distinguishable from its ambient levels. Other VOCs (xylene, trimethylbenzene, and styrene) were generally below <1 ppb. Unlike VOCs, the concentrations (ppb) of CCs were seen at fairly enhanced levels: 30.1-95 (formaldehyde), 34.6-87.2 (acetaldehyde), 4.56-34.7 (propionaldehyde), and 3.45-68.8 (butyraldehyde). The results of our study suggest that the back diffusion phenomenon, if occurring, can deteriorate in-vehicle air, especially with the most imminent health hazards from a compound such as formaldehyde in view of its exceedance pattern over common guidelines. Copyright © 2012 Elsevier B.V. All rights reserved.

Operation management system evaluation in the central Finland health care district - end users' view of system implementation.

PubMed

Lemmetty, Kaisa; Häyrinen, Eija

2005-01-01

In this paper we evaluate the implementation of the operation management system in the Central Finland Health Care District. The implementation of the operation management system changed the practice of operation management for the surgical clinic and concerned 500 personnel in total. A survey was carried out to investigate the end users' views on the system's usefulness, usability and the training and user support provided. The users' possibilities to accomplish their tasks and the kind of obstacles they face in operation management were explored. The assessment revealed that more end support is needed after the system implementation, even though a generally positive attitude towards the system was manifested among the staff.

Text mining a self-report back-translation.

PubMed

Blanch, Angel; Aluja, Anton

2016-06-01

There are several recommendations about the routine to undertake when back translating self-report instruments in cross-cultural research. However, text mining methods have been generally ignored within this field. This work describes a text mining innovative application useful to adapt a personality questionnaire to 12 different languages. The method is divided in 3 different stages, a descriptive analysis of the available back-translated instrument versions, a dissimilarity assessment between the source language instrument and the 12 back-translations, and an item assessment of item meaning equivalence. The suggested method contributes to improve the back-translation process of self-report instruments for cross-cultural research in 2 significant intertwined ways. First, it defines a systematic approach to the back translation issue, allowing for a more orderly and informed evaluation concerning the equivalence of different versions of the same instrument in different languages. Second, it provides more accurate instrument back-translations, which has direct implications for the reliability and validity of the instrument's test scores when used in different cultures/languages. In addition, this procedure can be extended to the back-translation of self-reports measuring psychological constructs in clinical assessment. Future research works could refine the suggested methodology and use additional available text mining tools. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Perceptions of general practitioners towards the use of a new system for treating back pain: a qualitative interview study.

PubMed

Sanders, Tom; Foster, Nadine E; Ong, Bie Nio

2011-05-09

Changing clinicians' behaviour is recognised as a major challenge. It is clear that behaviour change not only depends on demonstrating the proven effectiveness of clinical interventions; contextual and occupational factors, such as 'change readiness', may be central to their implementation. This paper highlights the context of behaviour change in relation to a healthcare innovation introduced within primary care, highlighting the importance of organisational and interpersonal factors that may help explain the dynamics of implementation. Qualitative interviews were conducted with general practitioners (GPs) before (n = 32) and after (n = 9) the introduction of a subgrouping for targeted treatment system. GPs were offered an electronic six-item subgrouping tool, to identify patients according to their risk of poor outcome ('high', 'low') in order to help inform their decision making about treatment approaches. Recruitment was based on a 'maximum diversification sample', to obtain a wide representation of views across all five practices. A coding scheme was developed based on the emergent findings, and the data were analysed using 'constant comparison', drawing upon insights and developing connections between themes. We adopted the normalisation process theory (NPT) to explain the uptake of the new system and to examine the relevance of coherence for the implementation of innovations in organisations. GPs perceived back pain as a low clinical priority, and highlighted the importance of 'practical' and 'relational' coherence in decisions to adopt and engage with the new subgrouping for targeted treatment system. Health professionals often engage in 'sense making' about new innovations to 'road test' their applicability or relevance to daily clinical routines. Low back pain was generally perceived as an 'uninteresting' and clinically unchallenging health problem by GPs, which may partly explain their lack of engagement with the new subgrouping for targeted treatment

Structure of the hexameric HerA ATPase reveals a mechanism of translocation-coupled DNA-end processing in archaea.

PubMed

Rzechorzek, Neil J; Blackwood, John K; Bray, Sian M; Maman, Joseph D; Pellegrini, Luca; Robinson, Nicholas P

2014-11-25

The HerA ATPase cooperates with the NurA nuclease and the Mre11-Rad50 complex for the repair of double-strand DNA breaks in thermophilic archaea. Here we extend our structural knowledge of this minimal end-resection apparatus by presenting the first crystal structure of hexameric HerA. The full-length structure visualizes at atomic resolution the N-terminal HerA-ATP synthase domain and a conserved C-terminal extension, which acts as a physical brace between adjacent protomers. The brace also interacts in trans with nucleotide-binding residues of the neighbouring subunit. Our observations support a model in which the coaxial interaction of the HerA ring with the toroidal NurA dimer generates a continuous channel traversing the complex. HerA-driven translocation would propel the DNA towards the narrow annulus of NurA, leading to duplex melting and nucleolytic digestion. This system differs substantially from the bacterial end-resection paradigms. Our findings suggest a novel mode of DNA-end processing by this integrated archaeal helicase-nuclease machine.

Heteropagus twinning on back -- a case report.

PubMed

Debnath, Bidyut; Biswas, Sumitra Kumar

2011-07-01

Heteropagus twins, also called parasitic twins, are malformation of the foetus where the development of one twin is incomplete. They are attached most commonly to the lower chest and upper abdomen. We report a case of heteropagus twin, where the parasite possessed well-formed limb as well as blind ending intestine. It was attached to the back of the host by a broad pedicle. We take this opportunity to classify areas of confusion prevailing regarding twinning, foetus in foetu, teratoma and caudal duplication.

Understanding cultural influences on back pain and back pain research.

PubMed

Henschke, Nicholas; Lorenz, Eva; Pokora, Roman; Michaleff, Zoe A; Quartey, Jonathan N A; Oliveira, Vinicius Cunha

2016-12-01

Low back pain is highly prevalent and places a considerable burden on individuals, their families and communities. This back pain burden is unequally distributed around the world and within populations. Clinicians and researchers addressing back pain should be aware of the cultural, social and political context of back pain patients and how this context can influence pain perception, disability and health care use. Culture, which influences the beliefs and behaviour of individuals within a social group, could be considered an important contributor to the unequal distribution of back pain. However, there is paucity of high-quality research exploring the influence of culture on the experience and management of back pain. Further development and testing of specific tools, assessment methods and communication strategies are needed to improve our understanding of how cultural practices, values and identifications affect those dealing with back pain. Copyright © 2017 Elsevier Ltd. All rights reserved.

Flavorings significantly affect inhalation toxicity of aerosol generated from electronic nicotine delivery systems (ENDS)

PubMed Central

Leigh, Noel J.; Lawton, Ralph I.; Hershberger, Pamela A.; Goniewicz, Maciej L.

2018-01-01

Background E-cigarettes or electronic nicotine delivery systems (ENDS) are designed to deliver nicotine-containing aerosol via inhalation. Little is known about the health effects of flavored ENDS aerosol when inhaled. Methods Aerosol from ENDS was generated using a smoking-machine. Various types of ENDS devices or a tank system prefilled with liquids of different flavors, nicotine carrier, variable nicotine concentrations, and with modified battery output voltage were tested. A convenience sample of commercial fluids with flavor names of tobacco, piña colada, menthol, coffee and strawberry were used. Flavoring chemicals were identified using gas chromatography/mass spectrometry. H292 human bronchial epithelial cells were directly exposed to 55 puffs of freshly-generated ENDS aerosol, tobacco smoke, or air (controls) using an air-liquid interface system and the Health Canada intense smoking protocol. The following in vitro toxicological effects were assessed: 1) cell viability, 2) metabolic activity and 3) release of inflammatory mediators (cytokines). Results Exposure to ENDS aerosol resulted in decreased metabolic activity and cell viability and increased release of IL-1β, IL-6, IL-10, CXCL1, CXCL2 and CXCL10 compared to air controls. Cell viability and metabolic activity were more adversely affected by conventional cigarettes than most tested ENDS products. Product type, battery output voltage, and flavors significantly affected toxicity of ENDS aerosol, with a strawberry-flavored product being the most cytotoxic. Conclusions Our data suggest that characteristics of ENDS products, including flavors, may induce inhalation toxicity. Therefore, ENDS users should use the products with caution until more comprehensive studies are performed. PMID:27633767

Electronic nicotine delivery system (ENDS) use during smoking cessation: a qualitative study of 40 Oklahoma quitline callers.