Sample records for background information sample

  1. Effects of background stimulation upon eye-movement information.

    PubMed

    Nakamura, S

    1996-04-01

    To investigate the effects of background stimulation upon eye-movement information (EMI), the perceived deceleration of the target motion during pursuit eye movement (Aubert-Fleishl paradox) was analyzed. In the experiment, a striped pattern was used as a background stimulus with various brightness contrasts and spatial frequencies for serially manipulating the attributions of the background stimulus. Analysis showed that the retinal-image motion of the background stimulus (optic flow) affected eye-movement information and that the effects of optic flow became stronger when high contrast and low spatial frequency stripes were presented as the background stimulus. In conclusion, optic flow is one source of eye-movement information in determining real object motion, and the effectiveness of optic flow depends on the attributes of the background stimulus.

  2. Effects of background motion on eye-movement information.

    PubMed

    Nakamura, S

    1997-02-01

    The effect of background stimulus on eye-movement information was investigated by analyzing the underestimation of the target velocity during pursuit eye movement (Aubert-Fleishl paradox). In the experiment, a striped pattern with various brightness contrasts and spatial frequencies was used as a background stimulus, which was moved at various velocities. Analysis showed that the perceived velocity of the pursuit target, which indicated the magnitudes of eye-movement information, decreased when the background stripes moved in the same direction as eye movement at higher velocities and increased when the background moved in the opposite direction. The results suggest that the eye-movement information varied as a linear function of the velocity of the motion of the background retinal image (optic flow). In addition, the effectiveness of optic flow on eye-movement information was determined by the attributes of the background stimulus such as the brightness contrast or the spatial frequency of the striped pattern.

  3. Acquisition of background and technical information and class trip planning

    NASA Technical Reports Server (NTRS)

    Mackinnon, R. M.; Wake, W. H.

    1981-01-01

    Instructors who are very familiar with a study area, as well as those who are not, find the field trip information acquisition and planning process speeded and made more effective by organizing it in stages. The stage follow a deductive progression: from the associated context region, to the study area, to the specific sample window sites, and from generalized background information on the study region to specific technical data on the environmental and human use systems to be interpreted at each site. On the class trip and in the follow up laboratory, the learning/interpretive process are at first deductive in applying previously learned information and skills to analysis of the study site, then inductive in reading and interpreting the landscape, imagery, and maps of the site, correlating them with information of other samples sites and building valid generalizations about the larger study area, its context region, and other (similar and/or contrasting) regions.

  4. The information content of cosmic microwave background anisotropies

    NASA Astrophysics Data System (ADS)

    Scott, Douglas; Contreras, Dagoberto; Narimani, Ali; Ma, Yin-Zhe

    2016-06-01

    The cosmic microwave background (CMB) contains perturbations that are close to Gaussian and isotropic. This means that its information content, in the sense of the ability to constrain cosmological models, is closely related to the number of modes probed in CMB power spectra. Rather than making forecasts for specific experimental setups, here we take a more pedagogical approach and ask how much information we can extract from the CMB if we are only limited by sample variance. We show that, compared with temperature measurements, the addition of E-mode polarization doubles the number of modes available out to a fixed maximum multipole, provided that all of the TT, TE, and EE power spectra are measured. However, the situation in terms of constraints on particular parameters is more complicated, as we explain and illustrate graphically. We also discuss the enhancements in information that can come from adding B-mode polarization and gravitational lensing. We show how well one could ever determine the basic cosmological parameters from CMB data compared with what has been achieved with Planck, which has already probed a substantial fraction of the TT information. Lastly, we look at constraints on neutrino mass as a specific example of how lensing information improves future prospects beyond the current 6-parameter model.

  5. The information content of cosmic microwave background anisotropies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott, Douglas; Contreras, Dagoberto; Narimani, Ali

    The cosmic microwave background (CMB) contains perturbations that are close to Gaussian and isotropic. This means that its information content, in the sense of the ability to constrain cosmological models, is closely related to the number of modes probed in CMB power spectra. Rather than making forecasts for specific experimental setups, here we take a more pedagogical approach and ask how much information we can extract from the CMB if we are only limited by sample variance. We show that, compared with temperature measurements, the addition of E -mode polarization doubles the number of modes available out to a fixedmore » maximum multipole, provided that all of the TT , TE , and EE power spectra are measured. However, the situation in terms of constraints on particular parameters is more complicated, as we explain and illustrate graphically. We also discuss the enhancements in information that can come from adding B -mode polarization and gravitational lensing. We show how well one could ever determine the basic cosmological parameters from CMB data compared with what has been achieved with Planck , which has already probed a substantial fraction of the TT information. Lastly, we look at constraints on neutrino mass as a specific example of how lensing information improves future prospects beyond the current 6-parameter model.« less

  6. Exploring Encoding and Retrieval Effects of Background Information on Text Memory

    ERIC Educational Resources Information Center

    Rawson, Katherine A.; Kintsch, Walter

    2004-01-01

    Two experiments were conducted (a) to evaluate how providing background information at test may benefit retrieval and (b) to further examine how providing background information prior to study influences encoding. Half of the participants read background information prior to study, and the other half did not. In each group, half were presented…

  7. Technical note: An improved approach to determining background aerosol concentrations with PILS sampling on aircraft

    NASA Astrophysics Data System (ADS)

    Fukami, Christine S.; Sullivan, Amy P.; Ryan Fulgham, S.; Murschell, Trey; Borch, Thomas; Smith, James N.; Farmer, Delphine K.

    2016-07-01

    Particle-into-Liquid Samplers (PILS) have become a standard aerosol collection technique, and are widely used in both ground and aircraft measurements in conjunction with off-line ion chromatography (IC) measurements. Accurate and precise background samples are essential to account for gas-phase components not efficiently removed and any interference in the instrument lines, collection vials or off-line analysis procedures. For aircraft sampling with PILS, backgrounds are typically taken with in-line filters to remove particles prior to sample collection once or twice per flight with more numerous backgrounds taken on the ground. Here, we use data collected during the Front Range Air Pollution and Photochemistry Éxperiment (FRAPPÉ) to demonstrate that not only are multiple background filter samples are essential to attain a representative background, but that the chemical background signals do not follow the Gaussian statistics typically assumed. Instead, the background signals for all chemical components analyzed from 137 background samples (taken from ∼78 total sampling hours over 18 flights) follow a log-normal distribution, meaning that the typical approaches of averaging background samples and/or assuming a Gaussian distribution cause an over-estimation of background samples - and thus an underestimation of sample concentrations. Our approach of deriving backgrounds from the peak of the log-normal distribution results in detection limits of 0.25, 0.32, 3.9, 0.17, 0.75 and 0.57 μg m-3 for sub-micron aerosol nitrate (NO3-), nitrite (NO2-), ammonium (NH4+), sulfate (SO42-), potassium (K+) and calcium (Ca2+), respectively. The difference in backgrounds calculated from assuming a Gaussian distribution versus a log-normal distribution were most extreme for NH4+, resulting in a background that was 1.58× that determined from fitting a log-normal distribution.

  8. Information sampling behavior with explicit sampling costs

    PubMed Central

    Juni, Mordechai Z.; Gureckis, Todd M.; Maloney, Laurence T.

    2015-01-01

    The decision to gather information should take into account both the value of information and its accrual costs in time, energy and money. Here we explore how people balance the monetary costs and benefits of gathering additional information in a perceptual-motor estimation task. Participants were rewarded for touching a hidden circular target on a touch-screen display. The target’s center coincided with the mean of a circular Gaussian distribution from which participants could sample repeatedly. Each “cue” — sampled one at a time — was plotted as a dot on the display. Participants had to repeatedly decide, after sampling each cue, whether to stop sampling and attempt to touch the hidden target or continue sampling. Each additional cue increased the participants’ probability of successfully touching the hidden target but reduced their potential reward. Two experimental conditions differed in the initial reward associated with touching the hidden target and the fixed cost per cue. For each condition we computed the optimal number of cues that participants should sample, before taking action, to maximize expected gain. Contrary to recent claims that people gather less information than they objectively should before taking action, we found that participants over-sampled in one experimental condition, and did not significantly under- or over-sample in the other. Additionally, while the ideal observer model ignores the current sample dispersion, we found that participants used it to decide whether to stop sampling and take action or continue sampling, a possible consequence of imperfect learning of the underlying population dispersion across trials. PMID:27429991

  9. Employment and Training Legislation-1968; Background Information.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Public Welfare.

    This volume supplied background information for employment and training legislation for the Committee on Labor and Public Welfare of the United States Senate for 1968. It includes: (1) excerpts from reports and recommendations of national committees and commissions on civil disorders, rural poverty, technology and automation, food and fiber, and…

  10. Stochastic, Adaptive Sampling of Information by Microvilli in Fly Photoreceptors

    PubMed Central

    Song, Zhuoyi; Postma, Marten; Billings, Stephen A.; Coca, Daniel; Hardie, Roger C.; Juusola, Mikko

    2012-01-01

    Summary Background In fly photoreceptors, light is focused onto a photosensitive waveguide, the rhabdomere, consisting of tens of thousands of microvilli. Each microvillus is capable of generating elementary responses, quantum bumps, in response to single photons using a stochastically operating phototransduction cascade. Whereas much is known about the cascade reactions, less is known about how the concerted action of the microvilli population encodes light changes into neural information and how the ultrastructure and biochemical machinery of photoreceptors of flies and other insects evolved in relation to the information sampling and processing they perform. Results We generated biophysically realistic fly photoreceptor models, which accurately simulate the encoding of visual information. By comparing stochastic simulations with single cell recordings from Drosophila photoreceptors, we show how adaptive sampling by 30,000 microvilli captures the temporal structure of natural contrast changes. Following each bump, individual microvilli are rendered briefly (∼100–200 ms) refractory, thereby reducing quantum efficiency with increasing intensity. The refractory period opposes saturation, dynamically and stochastically adjusting availability of microvilli (bump production rate: sample rate), whereas intracellular calcium and voltage adapt bump amplitude and waveform (sample size). These adapting sampling principles result in robust encoding of natural light changes, which both approximates perceptual contrast constancy and enhances novel events under different light conditions, and predict information processing across a range of species with different visual ecologies. Conclusions These results clarify why fly photoreceptors are structured the way they are and function as they do, linking sensory information to sensory evolution and revealing benefits of stochasticity for neural information processing. PMID:22704990

  11. The Institute of American Indian Arts Background Information (Task One of the Transition Evaluation). Background Paper.

    ERIC Educational Resources Information Center

    Tippeconnic, John W., Jr.

    The paper, prepared as Task One of the Institute of American Indian Arts Transition Evaluation, provides pertinent background information about the Institute of American Indian Arts in Santa Fe, New Mexico. A brief history of the Institute is given, with information about its philosophy and purpose; objectives; organization and administration; the…

  12. [Identification and sampling of people with migration background for epidemiological studies in Germany].

    PubMed

    Reiss, K; Makarova, N; Spallek, J; Zeeb, H; Razum, O

    2013-06-01

    In 2009, 19.6% of the population of Germany either had migrated themselves or were the offspring of people with migration experience. Migrants differ from the autochthonous German population in terms of health status, health awareness and health behaviour. To further investigate the health situation of migrants in Germany, epidemiological studies are needed. Such studies can employ existing databases which provide detailed information on migration status. Otherwise, onomastic or toponomastic procedures can be applied to identify people with migration background. If migrants have to be recruited into an epidemiological study, this can be done register-based (e. g., data from registration offices or telephone lists), based on residential location (random-route or random-walk procedure), via snowball sampling (e. g., through key persons) or via settings (e. g., school entry examination). An oversampling of people with migration background is not sufficient to avoid systematic bias in the sample due to non-participation. Additional measures have to be taken to increase access and raise participation rates. Personal contacting, multilingual instruments, multilingual interviewers and extensive public relations increase access and willingness to participate. Empirical evidence on 'successful' recruitment strategies for studies with migrants is still lacking in epidemiology and health sciences in Germany. The choice of the recruitment strategy as well as the measures to raise accessibility and willingness to participate depend on the available resources, the research question and the specific migrant target group. © Georg Thieme Verlag KG Stuttgart · New York.

  13. 29 CFR Appendix A to §§ 1605.2 and... - Background Information

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Background Information A Appendix A to §§ 1605.2 and 1605... §§ 1605.2 and 1605.3—Background Information In 1966, the Commission adopted guidelines on religious... of Trans World Airlines' business, and would therefore, exceed the duty to accommodate Hardison. In...

  14. 29 CFR Appendix A to §§ 1605.2 and... - Background Information

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Background Information A Appendix A to §§ 1605.2 and 1605... §§ 1605.2 and 1605.3—Background Information In 1966, the Commission adopted guidelines on religious... of Trans World Airlines' business, and would therefore, exceed the duty to accommodate Hardison. In...

  15. Resonant Raman scattering background in XRF spectra of binary samples

    NASA Astrophysics Data System (ADS)

    Sánchez, Héctor Jorge; Leani, Juan José

    2015-02-01

    In x-ray fluorescence analysis, spectra present singular characteristics produced by the different scattering processes. When atoms are irradiated with incident energy lower and close to an absorption edge, scattering peaks appear due to an inelastic process known as resonant Raman scattering. In this work we present theoretical calculations of the resonant Raman scattering contributions to the background of x-ray fluorescence spectra of binary samples of current technological or biological interest. On one hand, a binary alloy of Fe with traces of Mn (Mn: 0.01%, Fe: 99.99%) was studied because of its importance in the stainless steels industries. On the second hand a pure sample of Ti with V traces (Ti: 99%, V: 1%) was analyzed due to the current relevance in medical applications. In order to perform the calculations the Shiraiwa and Fujino's model was used to calculate characteristic intensities and scattering interactions. This model makes certain assumptions and approximations to achieve the calculations, especially in the case of the geometrical conditions and the incident and take-off beams. For the binary sample studied in this work and the considered experimental conditions, the calculations show that the resonant Raman scattering background is significant under the fluorescent peak, affects the symmetry of the peaks and, depending on the concentrations, overcomes the enhancements contributions (secondary fluorescence).

  16. Sample Collection Information Document for Chemical & ...

    EPA Pesticide Factsheets

    Report This Sample Collection Information Document (SCID) provides general information for use by EPA and its contractors when collecting samples during environmental remediation following a contamination incident. The document is intended to be used with SAM, and to provide information needed for collection of samples to be analyzed using the specific methods and procedures listed in SAM 2012 (EPA/600/R-12/555).

  17. Relation of Childhood Worry to Information-Processing Factors in an Ethnically Diverse Community Sample

    ERIC Educational Resources Information Center

    Suarez-Morales, Lourdes; Bell, Debora

    2006-01-01

    This study examined information-processing variables in relation to worry in a sample of 292 fifth-grade children from Caucasian, African American, and Hispanic backgrounds. Results revealed that worry was related to threat interpretations for hypothetical situations and, when stress level was not controlled, to higher estimates of future…

  18. Synthetic fiber production facilities: Background information for proposed standards

    NASA Astrophysics Data System (ADS)

    Goodwin, D. R.

    1982-10-01

    Standards of performance to control emissions of volatile organic compounds (VOC) from new, modified, and reconstructed synthetic fiber production facilities are being proposed under section III of the Clean Air Act. This document contains information on the background and authority, regulatory alternatives considered, and environmental and economic impacts of the regulatory alternatives.

  19. PPIS Information and Report Samples

    EPA Pesticide Factsheets

    Technical information about the Pesticide Product Information System and its downloadable file formats, and sample reporting for Federal Insecticide Fungicide and Rodenticide Act (FIFRA) section 3 and section 24(c).

  20. Separation of foreground and background from light field using gradient information.

    PubMed

    Lee, Jae Young; Park, Rae-Hong

    2017-02-01

    Studies of computer vision or machine vision applications using a light field camera have been increasing in recent years. However, the abilities that the light field camera has are not fully used in these applications. In this paper, we propose a method for direct separation of foreground and background that uses the gradient information and can be used in various applications such as pre-processing. From an optical phenomenon whereby the bundles of rays from the background are flipped, we derive that the disparity sign of the background in the captured three-dimensional scene has the opposite disparity sign of the foreground. Using the majority-weighted voting algorithm based on the gradient information with the Lambertian assumption and the gradient constraint, the foreground and background can be separated at each pixel. In regard to pre-processing, the proposed method can be used for various applications such as occlusion and saliency detection, disparity estimation, and so on. Experimental results with the EPFL light field dataset and Stanford Lytro light field dataset show that the proposed method achieves better performance in terms of the occlusion detection, and thus can be effectively used in pre-processing for saliency detection and disparity estimation.

  1. The Effects of Background Information on Standarized Test Scores.

    ERIC Educational Resources Information Center

    Feeley, Joan T.; Wepner, Shelley B.

    A study was conducted to determine the effects of exposure to the topics included on the comprehension subtest of the Nelson-Denny Reading Test (ND), Form F, on college freshmen's performance on the test. In addition, the study investigated whether those students with background information would indicate their awareness of this knowledge on a…

  2. Sample Collection Information Document for Pathogens and ...

    EPA Pesticide Factsheets

    Report This Sample Collection Information Document (SCID) provides general information for use by EPA and its contractors when collecting samples during environmental remediation following a homeland security event. The document is intended to be used with SAM, and to provide information needed for collection of samples to be analyzed using the specific methods and procedures listed in SAM Revision 5.0.*

  3. 76 FR 69287 - National Instant Criminal Background Check System Section Agency Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... System Section Agency Information Collection Activities: Existing collection, comments requested the Voluntary Appeal File (VAF) Brochure ACTION: 60-Day Notice of Information Collection Under Review. The... Criminal Background Check System (NICS) Section has submitted the following information collection request...

  4. VNIR hyperspectral background characterization methods in adverse weather conditions

    NASA Astrophysics Data System (ADS)

    Romano, João M.; Rosario, Dalton; Roth, Luz

    2009-05-01

    Hyperspectral technology is currently being used by the military to detect regions of interest where potential targets may be located. Weather variability, however, may affect the ability for an algorithm to discriminate possible targets from background clutter. Nonetheless, different background characterization approaches may facilitate the ability for an algorithm to discriminate potential targets over a variety of weather conditions. In a previous paper, we introduced a new autonomous target size invariant background characterization process, the Autonomous Background Characterization (ABC) or also known as the Parallel Random Sampling (PRS) method, features a random sampling stage, a parallel process to mitigate the inclusion by chance of target samples into clutter background classes during random sampling; and a fusion of results at the end. In this paper, we will demonstrate how different background characterization approaches are able to improve performance of algorithms over a variety of challenging weather conditions. By using the Mahalanobis distance as the standard algorithm for this study, we compare the performance of different characterization methods such as: the global information, 2 stage global information, and our proposed method, ABC, using data that was collected under a variety of adverse weather conditions. For this study, we used ARDEC's Hyperspectral VNIR Adverse Weather data collection comprised of heavy, light, and transitional fog, light and heavy rain, and low light conditions.

  5. Students Seeking Access to Four-Year Institutions: Community College Transfers [Background Information].

    ERIC Educational Resources Information Center

    Moore, Jamillah

    This publication provides background information for a hearing by the California Senate Select Committee on Higher Education and Outreach on December 3, 1997. The Introduction presents the Committee announcement, press release, agenda, information about transfer efforts in California, facts and figures about the community colleges, and the text of…

  6. Statistical Symbolic Execution with Informed Sampling

    NASA Technical Reports Server (NTRS)

    Filieri, Antonio; Pasareanu, Corina S.; Visser, Willem; Geldenhuys, Jaco

    2014-01-01

    Symbolic execution techniques have been proposed recently for the probabilistic analysis of programs. These techniques seek to quantify the likelihood of reaching program events of interest, e.g., assert violations. They have many promising applications but have scalability issues due to high computational demand. To address this challenge, we propose a statistical symbolic execution technique that performs Monte Carlo sampling of the symbolic program paths and uses the obtained information for Bayesian estimation and hypothesis testing with respect to the probability of reaching the target events. To speed up the convergence of the statistical analysis, we propose Informed Sampling, an iterative symbolic execution that first explores the paths that have high statistical significance, prunes them from the state space and guides the execution towards less likely paths. The technique combines Bayesian estimation with a partial exact analysis for the pruned paths leading to provably improved convergence of the statistical analysis. We have implemented statistical symbolic execution with in- formed sampling in the Symbolic PathFinder tool. We show experimentally that the informed sampling obtains more precise results and converges faster than a purely statistical analysis and may also be more efficient than an exact symbolic analysis. When the latter does not terminate symbolic execution with informed sampling can give meaningful results under the same time and memory limits.

  7. Information gains from cosmic microwave background experiments

    NASA Astrophysics Data System (ADS)

    Seehars, Sebastian; Amara, Adam; Refregier, Alexandre; Paranjape, Aseem; Akeret, Joël

    2014-07-01

    To shed light on the fundamental problems posed by dark energy and dark matter, a large number of experiments have been performed and combined to constrain cosmological models. We propose a novel way of quantifying the information gained by updates on the parameter constraints from a series of experiments which can either complement earlier measurements or replace them. For this purpose, we use the Kullback-Leibler divergence or relative entropy from information theory to measure differences in the posterior distributions in model parameter space from a pair of experiments. We apply this formalism to a historical series of cosmic microwave background experiments ranging from Boomerang to WMAP, SPT, and Planck. Considering different combinations of these experiments, we thus estimate the information gain in units of bits and distinguish contributions from the reduction of statistical errors and the "surprise" corresponding to a significant shift of the parameters' central values. For this experiment series, we find individual relative entropy gains ranging from about 1 to 30 bits. In some cases, e.g. when comparing WMAP and Planck results, we find that the gains are dominated by the surprise rather than by improvements in statistical precision. We discuss how this technique provides a useful tool for both quantifying the constraining power of data from cosmological probes and detecting the tensions between experiments.

  8. Staffing Preschools: Background Information.

    ERIC Educational Resources Information Center

    Katz, Lilian G.; Weir, Mary K.

    This report explores background variables related to preschool teaching, and emphasizes that statistics fluctuate in early childhood education. The increase for preprimary enrollment of 3- and 4-year-olds was 26 percent from 1966 to 1967. Accurate figures on preschool teaching personnel are not available, but a large proportion of Head Start…

  9. Rational learning and information sampling: on the "naivety" assumption in sampling explanations of judgment biases.

    PubMed

    Le Mens, Gaël; Denrell, Jerker

    2011-04-01

    Recent research has argued that several well-known judgment biases may be due to biases in the available information sample rather than to biased information processing. Most of these sample-based explanations assume that decision makers are "naive": They are not aware of the biases in the available information sample and do not correct for them. Here, we show that this "naivety" assumption is not necessary. Systematically biased judgments can emerge even when decision makers process available information perfectly and are also aware of how the information sample has been generated. Specifically, we develop a rational analysis of Denrell's (2005) experience sampling model, and we prove that when information search is interested rather than disinterested, even rational information sampling and processing can give rise to systematic patterns of errors in judgments. Our results illustrate that a tendency to favor alternatives for which outcome information is more accessible can be consistent with rational behavior. The model offers a rational explanation for behaviors that had previously been attributed to cognitive and motivational biases, such as the in-group bias or the tendency to prefer popular alternatives. 2011 APA, all rights reserved

  10. Robust sampling of decision information during perceptual choice

    PubMed Central

    Vandormael, Hildward; Herce Castañón, Santiago; Balaguer, Jan; Li, Vickie; Summerfield, Christopher

    2017-01-01

    Humans move their eyes to gather information about the visual world. However, saccadic sampling has largely been explored in paradigms that involve searching for a lone target in a cluttered array or natural scene. Here, we investigated the policy that humans use to overtly sample information in a perceptual decision task that required information from across multiple spatial locations to be combined. Participants viewed a spatial array of numbers and judged whether the average was greater or smaller than a reference value. Participants preferentially sampled items that were less diagnostic of the correct answer (“inlying” elements; that is, elements closer to the reference value). This preference to sample inlying items was linked to decisions, enhancing the tendency to give more weight to inlying elements in the final choice (“robust averaging”). These findings contrast with a large body of evidence indicating that gaze is directed preferentially to deviant information during natural scene viewing and visual search, and suggest that humans may sample information “robustly” with their eyes during perceptual decision-making. PMID:28223519

  11. Adaptive sampling of information in perceptual decision-making.

    PubMed

    Cassey, Thomas C; Evens, David R; Bogacz, Rafal; Marshall, James A R; Ludwig, Casimir J H

    2013-01-01

    In many perceptual and cognitive decision-making problems, humans sample multiple noisy information sources serially, and integrate the sampled information to make an overall decision. We derive the optimal decision procedure for two-alternative choice tasks in which the different options are sampled one at a time, sources vary in the quality of the information they provide, and the available time is fixed. To maximize accuracy, the optimal observer allocates time to sampling different information sources in proportion to their noise levels. We tested human observers in a corresponding perceptual decision-making task. Observers compared the direction of two random dot motion patterns that were triggered only when fixated. Observers allocated more time to the noisier pattern, in a manner that correlated with their sensory uncertainty about the direction of the patterns. There were several differences between the optimal observer predictions and human behaviour. These differences point to a number of other factors, beyond the quality of the currently available sources of information, that influences the sampling strategy.

  12. [Effects of exposure frequency and background information on preferences for photographs of cars in different locations].

    PubMed

    Matsuda, Ken; Kusumi, Takashi; Hosomi, Naohiro; Osa, Atsushi; Miike, Hidetoshi

    2014-08-01

    This study examined the influence of familiarity and novelty on the mere exposure effect while manipulating the presentation of background information. We selected presentation stimuli that integrated cars and backgrounds based on the results of pilot studies. During the exposure phase, we displayed the stimuli successively for 3 seconds, manipulating the background information (same or different backgrounds with each presentation) and exposure frequency (3, 6, and 9 times). In the judgment phase, 18 participants judged the cars in terms of preference, familiarity, and novelty on a 7-point scale. As the number of stimulus presentations increased, the preference for the cars increased during the different background condition and decreased during the same background condition. This increased preference may be due to the increase in familiarity caused by the higher exposure frequency and novelty resulting from the background changes per exposure session. The rise in preference judgments was not seen when cars and backgrounds were presented independently. Therefore, the addition of novel features to each exposure session facilitated the mere exposure effect.

  13. Informational analysis for compressive sampling in radar imaging.

    PubMed

    Zhang, Jingxiong; Yang, Ke

    2015-03-24

    Compressive sampling or compressed sensing (CS) works on the assumption of the sparsity or compressibility of the underlying signal, relies on the trans-informational capability of the measurement matrix employed and the resultant measurements, operates with optimization-based algorithms for signal reconstruction and is thus able to complete data compression, while acquiring data, leading to sub-Nyquist sampling strategies that promote efficiency in data acquisition, while ensuring certain accuracy criteria. Information theory provides a framework complementary to classic CS theory for analyzing information mechanisms and for determining the necessary number of measurements in a CS environment, such as CS-radar, a radar sensor conceptualized or designed with CS principles and techniques. Despite increasing awareness of information-theoretic perspectives on CS-radar, reported research has been rare. This paper seeks to bridge the gap in the interdisciplinary area of CS, radar and information theory by analyzing information flows in CS-radar from sparse scenes to measurements and determining sub-Nyquist sampling rates necessary for scene reconstruction within certain distortion thresholds, given differing scene sparsity and average per-sample signal-to-noise ratios (SNRs). Simulated studies were performed to complement and validate the information-theoretic analysis. The combined strategy proposed in this paper is valuable for information-theoretic orientated CS-radar system analysis and performance evaluation.

  14. Rational Learning and Information Sampling: On the "Naivety" Assumption in Sampling Explanations of Judgment Biases

    ERIC Educational Resources Information Center

    Le Mens, Gael; Denrell, Jerker

    2011-01-01

    Recent research has argued that several well-known judgment biases may be due to biases in the available information sample rather than to biased information processing. Most of these sample-based explanations assume that decision makers are "naive": They are not aware of the biases in the available information sample and do not correct for them.…

  15. Impaired information sampling in mild dementia of Alzheimer's type but not in healthy aging.

    PubMed

    Zamarian, Laura; Benke, Thomas; Brand, Matthias; Djamshidian, Atbin; Delazer, Margarete

    2015-05-01

    It is unknown whether aging affects predecisional processing, that is, gathering information and evaluating options before making a decision. Here, we investigated information sampling in mild Dementia of Alzheimer's type (DAT) and healthy aging by using the Information Sampling Task (IST). In a first investigation, we compared patients with mild DAT (n = 20) with healthy controls (n = 20) on the IST and several neuropsychological background tests. In a second investigation, healthy older adults (n = 30) were compared with younger adults (n = 30) on the IST and executive-function tasks. Results of the first investigation demonstrated that, in the IST, patients gathered significantly less information, made riskier and less accurate decisions, and showed less reward sensitivity relative to controls. We found a significant correlation between performance on the IST and performance on tests of verbal fluency, working memory, and recognition in patients but not in controls. Results of the second investigation indicated a largely similar performance pattern between healthy older adults and younger adults. There were no significant correlations for both groups between the IST and executive-function tasks. There are no relevant changes with healthy aging in predecisional processing. In contrast, mild DAT significantly affects predecisional information sampling. Thus, the problems shown in patients with mild DAT in decision making might be related to the patients' difficulties in predecisional processing. Decision-making performance in mild DAT might be improved by helping the patients at a predecisional stage to gather sufficient information and evaluate options more accurately. (c) 2015 APA, all rights reserved).

  16. Gathering Opinions on Depression Information Needs and Preferences: Samples and Opinions in Clinic Versus Web-Based Surveys

    PubMed Central

    Bernstein, Matthew T; Sexton, Kathryn A; Katz, Alan; Beatie, Brooke E

    2017-01-01

    Background There has been limited research on the information needs and preferences of the public concerning treatment for depression. Very little research is available comparing samples and opinions when recruitment for surveys is done over the Web as opposed to a personal invitation to complete a paper survey. Objective This study aimed to (1) to explore information needs and preferences among members of the public and (2) compare Clinic and Web samples on sample characteristics and survey findings. Methods Web survey participants were recruited with a notice on three self-help association websites (N=280). Clinic survey participants were recruited by a research assistant in the waiting rooms of a family medicine clinic and a walk-in medical clinic (N=238) and completed a paper version of the survey. Results The Clinic and Web samples were similar in age (39.0 years, SD 13.9 vs 40.2 years, SD 12.5, respectively), education, and proportion in full time employment. The Clinic sample was more diverse in demographic characteristics and closer to the demographic characteristics of the region (Winnipeg, Canada) with a higher proportion of males (102/238 [42.9%] vs 45/280 [16.1%]) and nonwhites (Aboriginal, Asian, and black) (69/238 [29.0%] vs 39/280 [13.9%]). The Web sample reported a higher level of emotional distress and had more previous psychological (224/280 [80.0%] vs 83/238 [34.9%]) and pharmacological (202/280 [72.1%] vs 57/238 [23.9%]) treatment. In terms of opinions, most respondents in both settings saw information on a wide range of topics around depression treatment as very important including information about treatment choices, effectiveness of treatment, how long it takes treatment to work, how long treatment continues, what happens when treatment stops, advantages and disadvantages of treatments, and potential side effects. Females, respondents with a white background, and those who had received or felt they would have benefited from therapy in the

  17. Distinguishing vegetation from soil background information. [by gray mapping of Landsat MSS data

    NASA Technical Reports Server (NTRS)

    Richardson, A. J.; Wiegand, C. L.

    1977-01-01

    In aircraft and satellite multispectral scanner data, soil background signals are superimposed on or intermingled with information about vegetation. A procedure which accounts for soil background would, therefore, make a considerable contribution to an operational use of Landsat and other spectral data for monitoring the productivity of range, forest, and crop lands. A description is presented of an investigation which was conducted to obtain information for the development of such a procedure. The investigation included a study of the soil reflectance that supplies the background signal of vegetated surfaces. Landsat data as recorded on computer compatible tapes were used in the study. The results of the investigation are discussed, taking into account a study reported by Kauth and Thomas (1976). Attention is given to the determination of Kauth's plane of soils, sun angle effects, vegetation index modeling, and the evaluation of vegetation indexes. Graphs are presented which show the results obtained with a gray mapping technique. The technique makes it possible to display plant, soil, water, and cloud conditions for any Landsat overpass.

  18. Sample Size in Qualitative Interview Studies: Guided by Information Power.

    PubMed

    Malterud, Kirsti; Siersma, Volkert Dirk; Guassora, Ann Dorrit

    2015-11-27

    Sample sizes must be ascertained in qualitative studies like in quantitative studies but not by the same means. The prevailing concept for sample size in qualitative studies is "saturation." Saturation is closely tied to a specific methodology, and the term is inconsistently applied. We propose the concept "information power" to guide adequate sample size for qualitative studies. Information power indicates that the more information the sample holds, relevant for the actual study, the lower amount of participants is needed. We suggest that the size of a sample with sufficient information power depends on (a) the aim of the study, (b) sample specificity, (c) use of established theory, (d) quality of dialogue, and (e) analysis strategy. We present a model where these elements of information and their relevant dimensions are related to information power. Application of this model in the planning and during data collection of a qualitative study is discussed. © The Author(s) 2015.

  19. Adaptive Sampling-Based Information Collection for Wireless Body Area Networks.

    PubMed

    Xu, Xiaobin; Zhao, Fang; Wang, Wendong; Tian, Hui

    2016-08-31

    To collect important health information, WBAN applications typically sense data at a high frequency. However, limited by the quality of wireless link, the uploading of sensed data has an upper frequency. To reduce upload frequency, most of the existing WBAN data collection approaches collect data with a tolerable error. These approaches can guarantee precision of the collected data, but they are not able to ensure that the upload frequency is within the upper frequency. Some traditional sampling based approaches can control upload frequency directly, however, they usually have a high loss of information. Since the core task of WBAN applications is to collect health information, this paper aims to collect optimized information under the limitation of upload frequency. The importance of sensed data is defined according to information theory for the first time. Information-aware adaptive sampling is proposed to collect uniformly distributed data. Then we propose Adaptive Sampling-based Information Collection (ASIC) which consists of two algorithms. An adaptive sampling probability algorithm is proposed to compute sampling probabilities of different sensed values. A multiple uniform sampling algorithm provides uniform samplings for values in different intervals. Experiments based on a real dataset show that the proposed approach has higher performance in terms of data coverage and information quantity. The parameter analysis shows the optimized parameter settings and the discussion shows the underlying reason of high performance in the proposed approach.

  20. Adaptive Sampling-Based Information Collection for Wireless Body Area Networks

    PubMed Central

    Xu, Xiaobin; Zhao, Fang; Wang, Wendong; Tian, Hui

    2016-01-01

    To collect important health information, WBAN applications typically sense data at a high frequency. However, limited by the quality of wireless link, the uploading of sensed data has an upper frequency. To reduce upload frequency, most of the existing WBAN data collection approaches collect data with a tolerable error. These approaches can guarantee precision of the collected data, but they are not able to ensure that the upload frequency is within the upper frequency. Some traditional sampling based approaches can control upload frequency directly, however, they usually have a high loss of information. Since the core task of WBAN applications is to collect health information, this paper aims to collect optimized information under the limitation of upload frequency. The importance of sensed data is defined according to information theory for the first time. Information-aware adaptive sampling is proposed to collect uniformly distributed data. Then we propose Adaptive Sampling-based Information Collection (ASIC) which consists of two algorithms. An adaptive sampling probability algorithm is proposed to compute sampling probabilities of different sensed values. A multiple uniform sampling algorithm provides uniform samplings for values in different intervals. Experiments based on a real dataset show that the proposed approach has higher performance in terms of data coverage and information quantity. The parameter analysis shows the optimized parameter settings and the discussion shows the underlying reason of high performance in the proposed approach. PMID:27589758

  1. Dimerization Products of Chloroprene are Background Contaminants Emitted from ALTEF (Polyvinylidene Difluoride) Gas Sampling Bags.

    PubMed

    Kwak, Jae; Fan, Maomian; Martin, Jennifer A; Ott, Darrin K; Grigsby, Claude C

    2017-01-01

    Gas sampling bags have been used for collecting air samples. Tedlar bags are most commonly used, but bleed background chemicals such as N,N-dimethylacetamide and phenol. It is often necessary to remove the contaminant by flushing the bags with pure nitrogen or air. In this study, we identified four chloroprene dimerization products as background contaminants emitted from ALTEF bags that are made of a proprietary polyvinylidene difluoride (PVDF). No monomer chloroprene was detected in the bags analyzed. All of the dimers gradually increased once bags were filled with nitrogen due to diffusion from the bag surface. Flushing the bags with nitrogen reduced their concentrations, but was not effective for removing the contaminants. When the bags that had been flushed with nitrogen 5 times were left for 24 h, they increased again, indicating that the dimers were constantly emitted from the ALTEF bag surface. To our knowledge, these compounds have never been demonstrated in ALTEF or other PVDF bags. Our finding indicates that ALTEF might be incorporated with Neoprene (chloroprene-based polymer) during its manufacturing process.

  2. A neural mechanism for background information-gated learning based on axonal-dendritic overlaps.

    PubMed

    Mainetti, Matteo; Ascoli, Giorgio A

    2015-03-01

    Experiencing certain events triggers the acquisition of new memories. Although necessary, however, actual experience is not sufficient for memory formation. One-trial learning is also gated by knowledge of appropriate background information to make sense of the experienced occurrence. Strong neurobiological evidence suggests that long-term memory storage involves formation of new synapses. On the short time scale, this form of structural plasticity requires that the axon of the pre-synaptic neuron be physically proximal to the dendrite of the post-synaptic neuron. We surmise that such "axonal-dendritic overlap" (ADO) constitutes the neural correlate of background information-gated (BIG) learning. The hypothesis is based on a fundamental neuroanatomical constraint: an axon must pass close to the dendrites that are near other neurons it contacts. The topographic organization of the mammalian cortex ensures that nearby neurons encode related information. Using neural network simulations, we demonstrate that ADO is a suitable mechanism for BIG learning. We model knowledge as associations between terms, concepts or indivisible units of thought via directed graphs. The simplest instantiation encodes each concept by single neurons. Results are then generalized to cell assemblies. The proposed mechanism results in learning real associations better than spurious co-occurrences, providing definitive cognitive advantages.

  3. A Neural Mechanism for Background Information-Gated Learning Based on Axonal-Dendritic Overlaps

    PubMed Central

    Mainetti, Matteo; Ascoli, Giorgio A.

    2015-01-01

    Experiencing certain events triggers the acquisition of new memories. Although necessary, however, actual experience is not sufficient for memory formation. One-trial learning is also gated by knowledge of appropriate background information to make sense of the experienced occurrence. Strong neurobiological evidence suggests that long-term memory storage involves formation of new synapses. On the short time scale, this form of structural plasticity requires that the axon of the pre-synaptic neuron be physically proximal to the dendrite of the post-synaptic neuron. We surmise that such “axonal-dendritic overlap” (ADO) constitutes the neural correlate of background information-gated (BIG) learning. The hypothesis is based on a fundamental neuroanatomical constraint: an axon must pass close to the dendrites that are near other neurons it contacts. The topographic organization of the mammalian cortex ensures that nearby neurons encode related information. Using neural network simulations, we demonstrate that ADO is a suitable mechanism for BIG learning. We model knowledge as associations between terms, concepts or indivisible units of thought via directed graphs. The simplest instantiation encodes each concept by single neurons. Results are then generalized to cell assemblies. The proposed mechanism results in learning real associations better than spurious co-occurrences, providing definitive cognitive advantages. PMID:25767887

  4. Optimal background matching camouflage.

    PubMed

    Michalis, Constantine; Scott-Samuel, Nicholas E; Gibson, David P; Cuthill, Innes C

    2017-07-12

    Background matching is the most familiar and widespread camouflage strategy: avoiding detection by having a similar colour and pattern to the background. Optimizing background matching is straightforward in a homogeneous environment, or when the habitat has very distinct sub-types and there is divergent selection leading to polymorphism. However, most backgrounds have continuous variation in colour and texture, so what is the best solution? Not all samples of the background are likely to be equally inconspicuous, and laboratory experiments on birds and humans support this view. Theory suggests that the most probable background sample (in the statistical sense), at the size of the prey, would, on average, be the most cryptic. We present an analysis, based on realistic assumptions about low-level vision, that estimates the distribution of background colours and visual textures, and predicts the best camouflage. We present data from a field experiment that tests and supports our predictions, using artificial moth-like targets under bird predation. Additionally, we present analogous data for humans, under tightly controlled viewing conditions, searching for targets on a computer screen. These data show that, in the absence of predator learning, the best single camouflage pattern for heterogeneous backgrounds is the most probable sample. © 2017 The Authors.

  5. Reappraising Abstract Paintings after Exposure to Background Information

    PubMed Central

    Park, Seongmin A.; Yun, Kyongsik; Jeong, Jaeseung

    2015-01-01

    Can knowledge help viewers when they appreciate an artwork? Experts’ judgments of the aesthetic value of a painting often differ from the estimates of naïve viewers, and this phenomenon is especially pronounced in the aesthetic judgment of abstract paintings. We compared the changes in aesthetic judgments of naïve viewers while they were progressively exposed to five pieces of background information. The participants were asked to report their aesthetic judgments of a given painting after each piece of information was presented. We found that commentaries by the artist and a critic significantly increased the subjective aesthetic ratings. Does knowledge enable experts to attend to the visual features in a painting and to link it to the evaluative conventions, thus potentially causing different aesthetic judgments? To investigate whether a specific pattern of attention is essential for the knowledge-based appreciation, we tracked the eye movements of subjects while viewing a painting with a commentary by the artist and with a commentary by a critic. We observed that critics’ commentaries directed the viewers’ attention to the visual components that were highly relevant to the presented commentary. However, attention to specific features of a painting was not necessary for increasing the subjective aesthetic judgment when the artists’ commentary was presented. Our results suggest that at least two different cognitive mechanisms may be involved in knowledge- guided aesthetic judgments while viewers reappraise a painting. PMID:25945789

  6. Raman background photobleaching as a possible method of cancer diagnostics

    NASA Astrophysics Data System (ADS)

    Brandt, Nikolai N.; Brandt, Nikolai B.; Chikishev, Andrey Y.; Gangardt, Mihail G.; Karyakina, Nina F.

    2001-06-01

    Kinetics of photobleaching of background in Raman spectra of aqueous solutions of plant toxins ricin and ricin agglutinin, ricin binding subunit, and normal and malignant human blood serum were measured. For the excitation of the spectra cw and pulsed laser radiation were used. The spectra of Raman background change upon laser irradiation. Background intensity is lower for the samples with small molecular weight. The cyclization of amino acid residues in the toxin molecules as well as in human blood serum can be a reason of the Raman background. The model of the background photobleaching is proposed. The differences in photobleaching kinetics in the cases of cw and pulsed laser radiation are discussed. It is shown that Raman background photobleaching can be very informative for cancer diagnostics.

  7. E-Mail Writing: Providing Background Information in the Core of Computer Assisted Instruction

    ERIC Educational Resources Information Center

    Nazari, Behzad; Ninknejad, Sahar

    2015-01-01

    The present study highly supported the effective role of providing background information via email by the teacher to write e-mail by the students in learners' writing ability. A total number of 50 EFL advanced male students aged between 25 and 40 at different branches of Iran Language Institute in Tehran, Tehran. Through the placement test of…

  8. Bayesian Analysis of the Cosmic Microwave Background

    NASA Technical Reports Server (NTRS)

    Jewell, Jeffrey

    2007-01-01

    There is a wealth of cosmological information encoded in the spatial power spectrum of temperature anisotropies of the cosmic microwave background! Experiments designed to map the microwave sky are returning a flood of data (time streams of instrument response as a beam is swept over the sky) at several different frequencies (from 30 to 900 GHz), all with different resolutions and noise properties. The resulting analysis challenge is to estimate, and quantify our uncertainty in, the spatial power spectrum of the cosmic microwave background given the complexities of "missing data", foreground emission, and complicated instrumental noise. Bayesian formulation of this problem allows consistent treatment of many complexities including complicated instrumental noise and foregrounds, and can be numerically implemented with Gibbs sampling. Gibbs sampling has now been validated as an efficient, statistically exact, and practically useful method for low-resolution (as demonstrated on WMAP 1 and 3 year temperature and polarization data). Continuing development for Planck - the goal is to exploit the unique capabilities of Gibbs sampling to directly propagate uncertainties in both foreground and instrument models to total uncertainty in cosmological parameters.

  9. Information-Theoretic Assessment of Sample Imaging Systems

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O.; Alter-Gartenberg, Rachel; Park, Stephen K.; Rahman, Zia-ur

    1999-01-01

    By rigorously extending modern communication theory to the assessment of sampled imaging systems, we develop the formulations that are required to optimize the performance of these systems within the critical constraints of image gathering, data transmission, and image display. The goal of this optimization is to produce images with the best possible visual quality for the wide range of statistical properties of the radiance field of natural scenes that one normally encounters. Extensive computational results are presented to assess the performance of sampled imaging systems in terms of information rate, theoretical minimum data rate, and fidelity. Comparisons of this assessment with perceptual and measurable performance demonstrate that (1) the information rate that a sampled imaging system conveys from the captured radiance field to the observer is closely correlated with the fidelity, sharpness and clarity with which the observed images can be restored and (2) the associated theoretical minimum data rate is closely correlated with the lowest data rate with which the acquired signal can be encoded for efficient transmission.

  10. Background characterization of an ultra-low background liquid scintillation counter

    DOE PAGES

    Erchinger, J. L.; Orrell, John L.; Aalseth, C. E.; ...

    2017-01-26

    The Ultra-Low Background Liquid Scintillation Counter developed by Pacific Northwest National Laboratory will expand the application of liquid scintillation counting by enabling lower detection limits and smaller sample volumes. By reducing the overall count rate of the background environment approximately 2 orders of magnitude below that of commercially available systems, backgrounds on the order of tens of counts per day over an energy range of ~3–3600 keV can be realized. Finally, initial test results of the ULB LSC show promising results for ultra-low background detection with liquid scintillation counting.

  11. Unexploded ordnance issues at Aberdeen Proving Ground: Background information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosenblatt, D.H.

    1996-11-01

    This document summarizes currently available information about the presence and significance of unexploded ordnance (UXO) in the two main areas of Aberdeen Proving Ground: Aberdeen Area and Edgewood Area. Known UXO in the land ranges of the Aberdeen Area consists entirely of conventional munitions. The Edgewood Area contains, in addition to conventional munitions, a significant quantity of chemical-munition UXO, which is reflected in the presence of chemical agent decomposition products in Edgewood Area ground-water samples. It may be concluded from current information that the UXO at Aberdeen Proving Ground has not adversely affected the environment through release of toxic substancesmore » to the public domain, especially not by water pathways, and is not likely to do so in the near future. Nevertheless, modest but periodic monitoring of groundwater and nearby surface waters would be a prudent policy.« less

  12. Conceptual Model of Clinical Governance Information System for Statistical Indicators by Using UML in Two Sample Hospitals

    PubMed Central

    Jeddi, Fatemeh Rangraz; Farzandipoor, Mehrdad; Arabfard, Masoud; Hosseini, Azam Haj Mohammad

    2016-01-01

    Objective: The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. Background: However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. Material and Methods: A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. Results: With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital’s clinical governance was required to create a database. Conclusion: Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems. PMID:27147804

  13. Conceptual Model of Clinical Governance Information System for Statistical Indicators by Using UML in Two Sample Hospitals

    PubMed Central

    Jeddi, Fatemeh Rangraz; Farzandipoor, Mehrdad; Arabfard, Masoud; Hosseini, Azam Haj Mohammad

    2014-01-01

    Objective: The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. Background: However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. Material and Methods: A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. Results: With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital’s clinical governance was required to create a database. Conclusion: Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems. PMID:24825933

  14. Stochastic, adaptive sampling of information by microvilli in fly photoreceptors.

    PubMed

    Song, Zhuoyi; Postma, Marten; Billings, Stephen A; Coca, Daniel; Hardie, Roger C; Juusola, Mikko

    2012-08-07

    In fly photoreceptors, light is focused onto a photosensitive waveguide, the rhabdomere, consisting of tens of thousands of microvilli. Each microvillus is capable of generating elementary responses, quantum bumps, in response to single photons using a stochastically operating phototransduction cascade. Whereas much is known about the cascade reactions, less is known about how the concerted action of the microvilli population encodes light changes into neural information and how the ultrastructure and biochemical machinery of photoreceptors of flies and other insects evolved in relation to the information sampling and processing they perform. We generated biophysically realistic fly photoreceptor models, which accurately simulate the encoding of visual information. By comparing stochastic simulations with single cell recordings from Drosophila photoreceptors, we show how adaptive sampling by 30,000 microvilli captures the temporal structure of natural contrast changes. Following each bump, individual microvilli are rendered briefly (~100-200 ms) refractory, thereby reducing quantum efficiency with increasing intensity. The refractory period opposes saturation, dynamically and stochastically adjusting availability of microvilli (bump production rate: sample rate), whereas intracellular calcium and voltage adapt bump amplitude and waveform (sample size). These adapting sampling principles result in robust encoding of natural light changes, which both approximates perceptual contrast constancy and enhances novel events under different light conditions, and predict information processing across a range of species with different visual ecologies. These results clarify why fly photoreceptors are structured the way they are and function as they do, linking sensory information to sensory evolution and revealing benefits of stochasticity for neural information processing. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Mutual information estimation for irregularly sampled time series

    NASA Astrophysics Data System (ADS)

    Rehfeld, K.; Marwan, N.; Heitzig, J.; Kurths, J.

    2012-04-01

    For the automated, objective and joint analysis of time series, similarity measures are crucial. Used in the analysis of climate records, they allow for a complimentary, unbiased view onto sparse datasets. The irregular sampling of many of these time series, however, makes it necessary to either perform signal reconstruction (e.g. interpolation) or to develop and use adapted measures. Standard linear interpolation comes with an inevitable loss of information and bias effects. We have recently developed a Gaussian kernel-based correlation algorithm with which the interpolation error can be substantially lowered, but this would not work should the functional relationship in a bivariate setting be non-linear. We therefore propose an algorithm to estimate lagged auto and cross mutual information from irregularly sampled time series. We have extended the standard and adaptive binning histogram estimators and use Gaussian distributed weights in the estimation of the (joint) probabilities. To test our method we have simulated linear and nonlinear auto-regressive processes with Gamma-distributed inter-sampling intervals. We have then performed a sensitivity analysis for the estimation of actual coupling length, the lag of coupling and the decorrelation time in the synthetic time series and contrast our results to the performance of a signal reconstruction scheme. Finally we applied our estimator to speleothem records. We compare the estimated memory (or decorrelation time) to that from a least-squares estimator based on fitting an auto-regressive process of order 1. The calculated (cross) mutual information results are compared for the different estimators (standard or adaptive binning) and contrasted with results from signal reconstruction. We find that the kernel-based estimator has a significantly lower root mean square error and less systematic sampling bias than the interpolation-based method. It is possible that these encouraging results could be further improved by

  16. Treatment of Nuclear Data Covariance Information in Sample Generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swiler, Laura Painton; Adams, Brian M.; Wieselquist, William

    This report summarizes a NEAMS (Nuclear Energy Advanced Modeling and Simulation) project focused on developing a sampling capability that can handle the challenges of generating samples from nuclear cross-section data. The covariance information between energy groups tends to be very ill-conditioned and thus poses a problem using traditional methods for generated correlated samples. This report outlines a method that addresses the sample generation from cross-section matrices.

  17. Italian: Area Background Information.

    ERIC Educational Resources Information Center

    Defense Language Inst., Washington, DC.

    This booklet has been assembled in order to provide students of Italian with a compact source of cultural information on their target area. Chapters include discussion of: (1) introduction to Italian; (2) origins of the Italian population; (3) geography; (4) history including the Roman Era, the Middle Ages, the Renaissance, the "Risorgimento," and…

  18. Repeated Random Sampling in Year 5

    ERIC Educational Resources Information Center

    Watson, Jane M.; English, Lyn D.

    2016-01-01

    As an extension to an activity introducing Year 5 students to the practice of statistics, the software "TinkerPlots" made it possible to collect repeated random samples from a finite population to informally explore students' capacity to begin reasoning with a distribution of sample statistics. This article provides background for the…

  19. Background Error Covariance Estimation Using Information from a Single Model Trajectory with Application to Ocean Data Assimilation

    NASA Technical Reports Server (NTRS)

    Keppenne, Christian L.; Rienecker, Michele; Kovach, Robin M.; Vernieres, Guillaume

    2014-01-01

    An attractive property of ensemble data assimilation methods is that they provide flow dependent background error covariance estimates which can be used to update fields of observed variables as well as fields of unobserved model variables. Two methods to estimate background error covariances are introduced which share the above property with ensemble data assimilation methods but do not involve the integration of multiple model trajectories. Instead, all the necessary covariance information is obtained from a single model integration. The Space Adaptive Forecast error Estimation (SAFE) algorithm estimates error covariances from the spatial distribution of model variables within a single state vector. The Flow Adaptive error Statistics from a Time series (FAST) method constructs an ensemble sampled from a moving window along a model trajectory.SAFE and FAST are applied to the assimilation of Argo temperature profiles into version 4.1 of the Modular Ocean Model (MOM4.1) coupled to the GEOS-5 atmospheric model and to the CICE sea ice model. The results are validated against unassimilated Argo salinity data. They show that SAFE and FAST are competitive with the ensemble optimal interpolation (EnOI) used by the Global Modeling and Assimilation Office (GMAO) to produce its ocean analysis. Because of their reduced cost, SAFE and FAST hold promise for high-resolution data assimilation applications.

  20. Orientations in adolescent use of information and communication technology: a digital divide by sociodemographic background, educational career, and health.

    PubMed

    Koivusilta, Leena K; Lintonen, Tomi P; Rimpelä, Arja H

    2007-01-01

    The role of information and communication technology (ICT) in adolescents' lives was studied, with emphasis on whether there exists a digital divide based on sociodemographic background, educational career, and health. The assumption was that some groups of adolescents use ICT more so that their information utilization skills improve (computer use), while others use it primarily for entertainment (digital gaming, contacting friends by mobile phone). Data were collected by mailed survey from a nationally representative sample of 12- to 18-year-olds (n=7,292; response 70%) in 2001 and analysed using ANOVA. Computer use was most frequent among adolescents whose fathers had higher education or socioeconomic status, who came from nuclear families, and who continued studies after compulsory education. Digital gaming was associated with poor school achievement and attending vocational rather than upper secondary school. Mobile phone use was frequent among adolescents whose fathers had lower education or socioeconomic status, who came from non-nuclear families, and whose educational prospects were poor. Intensive use of each ICT form, especially of mobile phones, was associated with health problems. High social position, nuclear family, and a successful educational career signified good health in general, independently of the diverse usage of ICT. There exists a digital divide among adolescents: orientation to computer use is more common in educated well-off families while digital gaming and mobile phone use accumulate at the opposite end of the spectrum. Poorest health was reported by mobile phone users. High social background and success at school signify better health, independently of the ways of using ICT.

  1. Radiocarbon dating of archaeological samples (sambaqui) using CO(2) absorption and liquid scintillation spectrometry of low background radiation.

    PubMed

    Mendonça, Maria Lúcia T G; Godoy, José M; da Cruz, Rosana P; Perez, Rhoneds A R

    2006-01-01

    Sambaqui means, in the Tupi language, a hill of shells. The sambaquis are archaeological sites with remains of pre-historical Brazilian occupation. Since the sambaqui sites in the Rio de Janeiro state region are older than 10,000 years, the applicability of CO(2) absorption on Carbo-sorb and (14)C determination by counting on a low background liquid scintillation counter was tested. In the present work, sambaqui shells were treated with H(3)PO(4) in a closed vessel in order to generate CO(2). The produced CO(2) was absorbed on Carbo-sorb. On saturation about 0.6g of carbon, as CO(2), was mixed with commercial liquid scintillation cocktail (Permafluor), and the (14)C activity determined by counting on a low background counter, Packard Tricarb 3170 TR/SL, for a period of 1000 mins to enable detection of a radiocarbon age of 22,400 BP. But only samples with ages up to 3500 BP were submitted to the method because the samples had been collected in the municipality of Guapimirim, in archaeological sambaqui-type sites belonging to this age range. The same samples were sent to the (14)C Laboratory of the Centro de Energia Nuclear na Agricultura (CENA/USP) where similar results were obtained.

  2. NATURAL RADIOACTIVITY LEVEL AND ELEMENTAL COMPOSITION OF SOIL SAMPLES FROM A HIGH BACKGROUND RADIATION AREA ON EASTERN COAST OF INDIA (ODISHA).

    PubMed

    Sahoo, S K; Kierepko, R; Sorimachi, A; Omori, Y; Ishikawa, T; Tokonami, S; Prasad, G; Gusain, G S; Ramola, R C

    2016-10-01

    A comprehensive study was carried out to determine the radioactivity concentration of soil samples from different sites of a high background radiation area in the eastern coast of India, Odisha state. The dose rate measured in situ varied from 0.25 to 1.2 µSv h -1 The gamma spectrometry measurements indicated Th series elements as the main contributors to the enhanced level of radiation and allowed the authors to find the mean level of the activity concentration (±SD) for 226 Ra, 228 Th and 40 K as 130±97, 1110±890 and 360±140 Bq kg -1 , respectively. Human exposure from radionuclides occurring outdoor was estimated based on the effective dose rate, which ranged from 0.14±0.02 to 2.15±0.26 mSv and was higher than the UNSCEAR annual worldwide average value 0.07 mSv. Additionally, X-ray fluorescence analysis provided information about the content of major elements in samples and indicated the significant amount of Ti (7.4±4.9 %) in soils. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Visual signal detection in structured backgrounds. II. Effects of contrast gain control, background variations, and white noise

    NASA Technical Reports Server (NTRS)

    Eckstein, M. P.; Ahumada, A. J. Jr; Watson, A. B.

    1997-01-01

    Studies of visual detection of a signal superimposed on one of two identical backgrounds show performance degradation when the background has high contrast and is similar in spatial frequency and/or orientation to the signal. To account for this finding, models include a contrast gain control mechanism that pools activity across spatial frequency, orientation and space to inhibit (divisively) the response of the receptor sensitive to the signal. In tasks in which the observer has to detect a known signal added to one of M different backgrounds grounds due to added visual noise, the main sources of degradation are the stochastic noise in the image and the suboptimal visual processing. We investigate how these two sources of degradation (contrast gain control and variations in the background) interact in a task in which the signal is embedded in one of M locations in a complex spatially varying background (structured background). We use backgrounds extracted from patient digital medical images. To isolate effects of the fixed deterministic background (the contrast gain control) from the effects of the background variations, we conduct detection experiments with three different background conditions: (1) uniform background, (2) a repeated sample of structured background, and (3) different samples of structured background. Results show that human visual detection degrades from the uniform background condition to the repeated background condition and degrades even further in the different backgrounds condition. These results suggest that both the contrast gain control mechanism and the background random variations degrade human performance in detection of a signal in a complex, spatially varying background. A filter model and added white noise are used to generate estimates of sampling efficiencies, an equivalent internal noise, an equivalent contrast-gain-control-induced noise, and an equivalent noise due to the variations in the structured background.

  4. Chemical Source Localization Fusing Concentration Information in the Presence of Chemical Background Noise.

    PubMed

    Pomareda, Víctor; Magrans, Rudys; Jiménez-Soto, Juan M; Martínez, Dani; Tresánchez, Marcel; Burgués, Javier; Palacín, Jordi; Marco, Santiago

    2017-04-20

    We present the estimation of a likelihood map for the location of the source of a chemical plume dispersed under atmospheric turbulence under uniform wind conditions. The main contribution of this work is to extend previous proposals based on Bayesian inference with binary detections to the use of concentration information while at the same time being robust against the presence of background chemical noise. For that, the algorithm builds a background model with robust statistics measurements to assess the posterior probability that a given chemical concentration reading comes from the background or from a source emitting at a distance with a specific release rate. In addition, our algorithm allows multiple mobile gas sensors to be used. Ten realistic simulations and ten real data experiments are used for evaluation purposes. For the simulations, we have supposed that sensors are mounted on cars which do not have among its main tasks navigating toward the source. To collect the real dataset, a special arena with induced wind is built, and an autonomous vehicle equipped with several sensors, including a photo ionization detector (PID) for sensing chemical concentration, is used. Simulation results show that our algorithm, provides a better estimation of the source location even for a low background level that benefits the performance of binary version. The improvement is clear for the synthetic data while for real data the estimation is only slightly better, probably because our exploration arena is not able to provide uniform wind conditions. Finally, an estimation of the computational cost of the algorithmic proposal is presented.

  5. Information Seeking Behavior of Geologists When Searching for Physical Samples

    ERIC Educational Resources Information Center

    Ramdeen, Sarah

    2017-01-01

    Information seeking is "a conscious effort to acquire information in response to a need or gap" in your knowledge (Case, 2007, p. 5). In the geosciences, physical samples such as cores, cuttings, fossils, and rocks are primary sources of information; they represent "the foundation of basic and applied geoscience research and…

  6. Gathering Opinions on Depression Information Needs and Preferences: Samples and Opinions in Clinic Versus Web-Based Surveys.

    PubMed

    Bernstein, Matthew T; Walker, John R; Sexton, Kathryn A; Katz, Alan; Beatie, Brooke E

    2017-04-24

    There has been limited research on the information needs and preferences of the public concerning treatment for depression. Very little research is available comparing samples and opinions when recruitment for surveys is done over the Web as opposed to a personal invitation to complete a paper survey. This study aimed to (1) to explore information needs and preferences among members of the public and (2) compare Clinic and Web samples on sample characteristics and survey findings. Web survey participants were recruited with a notice on three self-help association websites (N=280). Clinic survey participants were recruited by a research assistant in the waiting rooms of a family medicine clinic and a walk-in medical clinic (N=238) and completed a paper version of the survey. The Clinic and Web samples were similar in age (39.0 years, SD 13.9 vs 40.2 years, SD 12.5, respectively), education, and proportion in full time employment. The Clinic sample was more diverse in demographic characteristics and closer to the demographic characteristics of the region (Winnipeg, Canada) with a higher proportion of males (102/238 [42.9%] vs 45/280 [16.1%]) and nonwhites (Aboriginal, Asian, and black) (69/238 [29.0%] vs 39/280 [13.9%]). The Web sample reported a higher level of emotional distress and had more previous psychological (224/280 [80.0%] vs 83/238 [34.9%]) and pharmacological (202/280 [72.1%] vs 57/238 [23.9%]) treatment. In terms of opinions, most respondents in both settings saw information on a wide range of topics around depression treatment as very important including information about treatment choices, effectiveness of treatment, how long it takes treatment to work, how long treatment continues, what happens when treatment stops, advantages and disadvantages of treatments, and potential side effects. Females, respondents with a white background, and those who had received or felt they would have benefited from therapy in the past saw more information topics as very

  7. Backgrounds in Language.

    ERIC Educational Resources Information Center

    Maxwell, John C.; Long, Barbara K.

    "Backgrounds in Language," a field-tested inservice course designed for use by groups of 15 or 25 language arts teachers, provides the subject matter background teachers need to make informed decisions about what curriculum materials to use in what way, at what time, and with which students. The course is comprised of eight 2-hour sessions,…

  8. Global information sampling in the honey bee

    NASA Astrophysics Data System (ADS)

    Johnson, Brian R.

    2008-06-01

    Central to the question of task allocation in social insects is how workers acquire information. Patrolling is a curious behavior in which bees meander over the face of the comb inspecting cells. Several authors have suggested it allows bees to collect global information, but this has never been formally evaluated. This study explores this hypothesis by answering three questions. First, do bees gather information in a consistent manner as they patrol? Second, do they move far enough to get a sense of task demand in distant areas of the nest? And third, is patrolling a commonly performed task? Focal animal observations were used to address the first two predictions, while a scan sampling study was used to address the third. The results were affirmative for each question. While patrolling, workers collected information by performing periodic clusters of cell inspections. Patrolling bees not only traveled far enough to frequently change work zone; they often visited every part of the nest. Finally, the majority of the bees in the middle-age caste were shown to move throughout the nest over the course of a few hours in a manner suggestive of patrolling. Global information collection is contrary to much current theory, which assumes that workers respond to local information only. This study thus highlights the nonmutually exclusive nature of various information collection regimes in social insects.

  9. Why background colour matters to bees and flowers.

    PubMed

    Bukovac, Zoë; Shrestha, Mani; Garcia, Jair E; Burd, Martin; Dorin, Alan; Dyer, Adrian G

    2017-05-01

    Flowers are often viewed by bee pollinators against a variety of different backgrounds. On the Australian continent, backgrounds are very diverse and include surface examples of all major geological stages of the Earth's history, which have been present during the entire evolutionary period of Angiosperms. Flower signals in Australia are also representative of typical worldwide evolutionary spectral adaptations that enable successful pollination. We measured the spectral properties of 581 natural surfaces, including rocks, sand, green leaves, and dry plant materials, sampled from tropical Cairns through to the southern tip of mainland Australia. We modelled in a hexagon colour space, how interactions between background spectra and flower-like colour stimuli affect reliable discrimination and detection in bee pollinators. We calculated the extent to which a given locus would be conflated with the loci of a different flower-colour stimulus using empirically determined colour discrimination regions for bee vision. Our results reveal that whilst colour signals are robust in homogeneous background viewing conditions, there could be significant pressure on plant flowers to evolve saliently-different colours to overcome background spectral noise. We thus show that perceptual noise has a large influence on how colour information can be used in natural conditions.

  10. A rapid method for the simultaneous determination of gross alpha and beta activities in water samples using a low background liquid scintillation counter.

    PubMed

    Sanchez-Cabeza, J A; Pujol, L

    1995-05-01

    The radiological examination of water requires a rapid screening technique that permits the determination of the gross alpha and beta activities of each sample in order to decide if further radiological analyses are necessary. In this work, the use of a low background liquid scintillation system (Quantulus 1220) is proposed to simultaneously determine the gross activities in water samples. Liquid scintillation is compared to more conventional techniques used in most monitoring laboratories. In order to determine the best counting configuration of the system, pulse shape discrimination was optimized for 6 scintillant/vial combinations. It was concluded that the best counting configuration was obtained with the scintillation cocktail Optiphase Hisafe 3 in Zinsser low diffusion vials. The detection limits achieved were 0.012 Bq L-1 and 0.14 Bq L-1 for gross alpha and beta activity respectively, after a 1:10 concentration process by simple evaporation and for a counting time of only 360 min. The proposed technique is rapid, gives spectral information, and is adequate to determine gross activities according to the World Health Organization (WHO) guideline values.

  11. Experiences with nutrition-related information during antenatal care of pregnant women of different ethnic backgrounds residing in the area of Oslo, Norway.

    PubMed

    Garnweidner, Lisa M; Sverre Pettersen, Kjell; Mosdøl, Annhild

    2013-12-01

    to explore experiences with nutrition-related information during routine antenatal care among women of different ethnical backgrounds. individual interviews with seventeen participants were conducted twice during pregnancy. Data collection and analysis were inspired by an interpretative phenomenological approach. participants were purposively recruited at eight Mother and Child Health Centres in the area of Oslo, Norway, where they received antenatal care. participants had either immigrant backgrounds from African and Asian countries (n=12) or were ethnic Norwegian (n=5). Participants were pregnant with their first child and had a pre-pregnancy Body Mass Index above 25 kg/m(2). participants experienced that they were provided with little nutrition-related information in antenatal care. The information was perceived as presented in very general terms and focused on food safety. Weight management and the long-term prevention of diet-related chronic diseases had hardly been discussed. Participants with immigrant backgrounds appeared to be confused about information given by the midwife which was incongruent with their original food culture. The participants were actively seeking for nutrition-related information and had to navigate between various sources of information. the midwife is considered a trustworthy source of nutrition-related information. Therefore, antenatal care may have considerable potential to promote a healthy diet to pregnant women. Findings suggest that nutrition communication in antenatal care should be more tailored towards women's dietary habits and cultural background, nutritional knowledge as well as level of nutrition literacy. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Comparative Financial Statistics for Public Two-Year Colleges: FY 1993 Peer Group Sample.

    ERIC Educational Resources Information Center

    Dickmeyer, Nathan; Meeker, Bradley

    Comparative financial information derived from a national sample of 516 two-year colleges is presented in this report for fiscal year 1992-93, including statistics for the national sample and for six peer groups. The report's nine sections focus on: (1) introductory information about the study's background, objectives, and sample; the National…

  13. Spectral feature characterization methods for blood stain detection in crime scene backgrounds

    NASA Astrophysics Data System (ADS)

    Yang, Jie; Mathew, Jobin J.; Dube, Roger R.; Messinger, David W.

    2016-05-01

    Blood stains are one of the most important types of evidence for forensic investigation. They contain valuable DNA information, and the pattern of the stains can suggest specifics about the nature of the violence that transpired at the scene. Blood spectral signatures containing unique reflectance or absorption features are important both for forensic on-site investigation and laboratory testing. They can be used for target detection and identification applied to crime scene hyperspectral imagery, and also be utilized to analyze the spectral variation of blood on various backgrounds. Non-blood stains often mislead the detection and can generate false alarms at a real crime scene, especially for dark and red backgrounds. This paper measured the reflectance of liquid blood and 9 kinds of non-blood samples in the range of 350 nm - 2500 nm in various crime scene backgrounds, such as pure samples contained in petri dish with various thicknesses, mixed samples with different colors and materials of fabrics, and mixed samples with wood, all of which are examined to provide sub-visual evidence for detecting and recognizing blood from non-blood samples in a realistic crime scene. The spectral difference between blood and non-blood samples are examined and spectral features such as "peaks" and "depths" of reflectance are selected. Two blood stain detection methods are proposed in this paper. The first method uses index to denote the ratio of "depth" minus "peak" over"depth" add"peak" within a wavelength range of the reflectance spectrum. The second method uses relative band depth of the selected wavelength ranges of the reflectance spectrum. Results show that the index method is able to discriminate blood from non-blood samples in most tested crime scene backgrounds, but is not able to detect it from black felt. Whereas the relative band depth method is able to discriminate blood from non-blood samples on all of the tested background material types and colors.

  14. GROUND WATER ISSUE: LOW-FLOW (MINIMAL DRAWDOWN) GROUND-WATER SAMPLING PROCEDURES

    EPA Science Inventory

    This paper is intended to provide background information on the development of low-flow sampling procedures and its application under a variety of hydrogeologic settings. The sampling methodology described in this paper assumes that the monitoring goal is to sample monitoring wel...

  15. 45 CFR Appendix B to Part 2507 - Freedom of Information Act Appeal for Release of Information (Sample)

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Freedom of Information Act Appeal for Release of Information (Sample) B Appendix B to Part 2507 Public Welfare Regulations Relating to Public Welfare... FREEDOM OF INFORMATION ACT Pt. 2507, App. B Appendix B to Part 2507—Freedom of Information Act Appeal for...

  16. 45 CFR Appendix B to Part 2507 - Freedom of Information Act Appeal for Release of Information (Sample)

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Freedom of Information Act Appeal for Release of Information (Sample) B Appendix B to Part 2507 Public Welfare Regulations Relating to Public Welfare... FREEDOM OF INFORMATION ACT Pt. 2507, App. B Appendix B to Part 2507—Freedom of Information Act Appeal for...

  17. Uncertainty in sample estimates and the implicit loss function for soil information.

    NASA Astrophysics Data System (ADS)

    Lark, Murray

    2015-04-01

    One significant challenge in the communication of uncertain information is how to enable the sponsors of sampling exercises to make a rational choice of sample size. One way to do this is to compute the value of additional information given the loss function for errors. The loss function expresses the costs that result from decisions made using erroneous information. In certain circumstances, such as remediation of contaminated land prior to development, loss functions can be computed and used to guide rational decision making on the amount of resource to spend on sampling to collect soil information. In many circumstances the loss function cannot be obtained prior to decision making. This may be the case when multiple decisions may be based on the soil information and the costs of errors are hard to predict. The implicit loss function is proposed as a tool to aid decision making in these circumstances. Conditional on a logistical model which expresses costs of soil sampling as a function of effort, and statistical information from which the error of estimates can be modelled as a function of effort, the implicit loss function is the loss function which makes a particular decision on effort rational. In this presentation the loss function is defined and computed for a number of arbitrary decisions on sampling effort for a hypothetical soil monitoring problem. This is based on a logistical model of sampling cost parameterized from a recent geochemical survey of soil in Donegal, Ireland and on statistical parameters estimated with the aid of a process model for change in soil organic carbon. It is shown how the implicit loss function might provide a basis for reflection on a particular choice of sample size by comparing it with the values attributed to soil properties and functions. Scope for further research to develop and apply the implicit loss function to help decision making by policy makers and regulators is then discussed.

  18. 7 CFR 61.42 - Information on sampling to be kept confidential.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... licensed under the act as a sampler of cottonseed shall keep confidential all information secured by him relative to shipments of cottonseed sampled by him. He shall not disclose such information to any person...

  19. Background Mole Fractions of Hydrocarbons in North America Determined from NOAA Global Reference Network Data

    NASA Astrophysics Data System (ADS)

    Mielke-Maday, I.

    2015-12-01

    The National Oceanic and Atmospheric Administration (NOAA) Global Monitoring Division (GMD) maintains a global reference network for over 50 trace gas species and analyzes discrete air samples collected by this network throughout the world at the Earth System Research Laboratory in Boulder, Colorado. In particular, flask samples are analyzed for a number of hydrocarbons with policy and health relevance such as ozone precursors, greenhouse gases, and hazardous air pollutants. Because this global network's sites are remote and therefore minimally influenced by local anthropogenic emissions, these data yield information about background ambient mole fractions and can provide a context for observations collected in intensive field campaigns, such as the Front Range Air Pollution and Photochemistry Experiment (FRAPPE), the Southeast Nexus (SENEX) study, and the DISCOVER-AQ deployments. Information about background mole fractions during field campaigns is critical for calculating hydrocarbon enhancements in the region of study and for assessing the extent to which a particular region's local emissions sources contribute to these enhancements. Understanding the geographic variability of the background and its contribution to regional ambient mole fractions is also crucial for the development of realistic regulations. We present background hydrocarbon mole fractions and their ratios in North America using data from air samples collected in the planetary boundary layer at tall towers and aboard aircraft from 2008 to 2014. We discuss the spatial and seasonal variability in these data. We present trends over the time period of measurements and propose possible explanations for these trends.

  20. Integrating clinical and biological information in a shanghai biobank: an introduction to the sample repository and information sharing platform project.

    PubMed

    Cui, Wenbin; Zheng, Peiyong; Yang, Jiahong; Zhao, Rong; Gao, Jiechun; Yu, Guangjun

    2015-02-01

    Biobanks are important resources and central tools for translational medicine, which brings scientific research outcomes to clinical practice. The key purpose of biobanking in translational medicine and other medical research is to provide biological samples that are integrated with clinical information. In 2008, the Shanghai Municipal Government launched the "Shanghai Tissue Bank" in an effort to promote research in translational medicine. Now a sharing service platform has been constructed to integrate clinical practice and biological information that can be used in diverse medical and pharmaceutical research studies. The platform collects two kinds of data: sample data and clinical data. The sample data are obtained from the hospital biobank management system, and mainly include the donors' age, gender, marital status, sample source, sample type, collection time, deposit time, and storage method. The clinical data are collected from the "Hospital-Link" system (a medical information sharing system that connects 23 tertiary hospitals in Shanghai). The main contents include donors' corresponding medication information, test reports, inspection reports, and hospital information. As of the end of September 2014, the project has a collection of 16,020 donors and 148,282 samples, which were obtained from 12 medical institutions, and automatically acquired donors' corresponding clinical data from the "Hospital-Link" system for 6830 occurrences. This project will contribute to scientific research at medical institutions in Shanghai, and will also support the development of the biopharmaceutical industry. In this article, we will describe the significance, the construction phases, the application prospects, and benefits of the sample repository and information sharing service platform.

  1. Effect of display update interval, update type, and background on perception of aircraft separation on a cockpit display on traffic information

    NASA Technical Reports Server (NTRS)

    Jago, S.; Baty, D.; Oconnor, S.; Palmer, E.

    1981-01-01

    The concept of a cockpit display of traffic information (CDTI) includes the integration of air traffic, navigation, and other pertinent information in a single electronic display in the cockpit. Concise display symbology was developed for use in later full-mission simulator evaluations of the CDTI concept. Experimental variables used included the update interval motion of the aircraft, the update type, (that is, whether the two aircraft were updated at the same update interval or not), the background (grid pattern or no background), and encounter type (straight or curved). Only the type of encounter affected performance.

  2. Nondestructive determination of radionuclides in lunar samples using a large low-background gamma-ray spectrometer and a novel application of least-squares fitting

    NASA Technical Reports Server (NTRS)

    Eldridge, J. S.; Okelly, G. D.; Northcutt, K. J.; Schonfeld, E.

    1972-01-01

    Dual-parameter gamma ray spectrometer systems with large volume Nal (Tl) crystals and low backgrounds were used for nondestructive determination of K, Th, U and cosmic ray produced radionuclides in 60 lunar samples. The total weight of samples measured with this system is 28 kg, and the individual sample weights varied from 2 to 2300 g. Samples from Apollo 11, 12, 14, 15 and 16 were measured. Operation of the spectrometers in the coincidence mode and analyzing single coincidence spectra permits the simultaneous determination of 8-10 radionuclides in each lunar sample.

  3. Estimating the Expected Value of Sample Information Using the Probabilistic Sensitivity Analysis Sample

    PubMed Central

    Oakley, Jeremy E.; Brennan, Alan; Breeze, Penny

    2015-01-01

    Health economic decision-analytic models are used to estimate the expected net benefits of competing decision options. The true values of the input parameters of such models are rarely known with certainty, and it is often useful to quantify the value to the decision maker of reducing uncertainty through collecting new data. In the context of a particular decision problem, the value of a proposed research design can be quantified by its expected value of sample information (EVSI). EVSI is commonly estimated via a 2-level Monte Carlo procedure in which plausible data sets are generated in an outer loop, and then, conditional on these, the parameters of the decision model are updated via Bayes rule and sampled in an inner loop. At each iteration of the inner loop, the decision model is evaluated. This is computationally demanding and may be difficult if the posterior distribution of the model parameters conditional on sampled data is hard to sample from. We describe a fast nonparametric regression-based method for estimating per-patient EVSI that requires only the probabilistic sensitivity analysis sample (i.e., the set of samples drawn from the joint distribution of the parameters and the corresponding net benefits). The method avoids the need to sample from the posterior distributions of the parameters and avoids the need to rerun the model. The only requirement is that sample data sets can be generated. The method is applicable with a model of any complexity and with any specification of model parameter distribution. We demonstrate in a case study the superior efficiency of the regression method over the 2-level Monte Carlo method. PMID:25810269

  4. 45 CFR Appendix B to Part 2507 - Freedom of Information Act Appeal for Release of Information (Sample)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Freedom of Information Act Appeal for Release of Information (Sample) B Appendix B to Part 2507 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROCEDURES FOR DISCLOSURE OF RECORDS UNDER THE FREEDOM OF INFORMATION ACT Pt. 2507, App. B...

  5. Taiwan: Background Notes Series.

    ERIC Educational Resources Information Center

    Reams, Joanne Reppert

    Concise background information on Taiwan is provided. The publication begins with a profile of Taiwan, discussing the people, geography, political establishment, and economy. A map of the country is provided. The bulk of the publication then provides more detailed information on Taiwan's people, geography, history, administration, political…

  6. 47 CFR 215.1 - Background.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Background. 215.1 Section 215.1 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic...

  7. 47 CFR 215.1 - Background.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Background. 215.1 Section 215.1 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic...

  8. 47 CFR 215.1 - Background.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Background. 215.1 Section 215.1 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic...

  9. 47 CFR 215.1 - Background.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Background. 215.1 Section 215.1 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic...

  10. 47 CFR 215.1 - Background.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Background. 215.1 Section 215.1 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic...

  11. Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection

    PubMed Central

    Mertz, Jerome; Kim, Jinhyun

    2010-01-01

    It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast. PMID:20210471

  12. Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection.

    PubMed

    Mertz, Jerome; Kim, Jinhyun

    2010-01-01

    It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast.

  13. Scanning light-sheet microscopy in the whole mouse brain with HiLo background rejection

    NASA Astrophysics Data System (ADS)

    Mertz, Jerome; Kim, Jinhyun

    2010-01-01

    It is well known that light-sheet illumination can enable optically sectioned wide-field imaging of macroscopic samples. However, the optical sectioning capacity of a light-sheet macroscope is undermined by sample-induced scattering or aberrations that broaden the thickness of the sheet illumination. We present a technique to enhance the optical sectioning capacity of a scanning light-sheet microscope by out-of-focus background rejection. The technique, called HiLo microscopy, makes use of two images sequentially acquired with uniform and structured sheet illumination. An optically sectioned image is then synthesized by fusing high and low spatial frequency information from both images. The benefits of combining light-sheet macroscopy and HiLo background rejection are demonstrated in optically cleared whole mouse brain samples, using both green fluorescent protein (GFP)-fluorescence and dark-field scattered light contrast.

  14. Using Lunar Sample Disks and Resources to Promote Scientific Inquiry

    NASA Technical Reports Server (NTRS)

    Graff, Paige; Allen, Jaclyn; Runco, Susan

    2014-01-01

    This poster presentation will illustrate the use of NASA Lunar Sample Disks and resources to promote scientific inquiry and address the Next Generation Science Standards. The poster will present information on the Lunar Sample Disks, housed and managed by the Astromaterials Research and Exploration Science (ARES) Directorate at the NASA Johnson Space Center. The poster will also present information on an inquiry-based planetary sample and impact cratering unit designed to introduce students in grades 4-10 to the significance of studying the rocks, soils, and surfaces of a planetary world. The unit, consisting of many hands-on activities, provides context and background information to enhance the impact of the Lunar Sample Disks.

  15. Geographical Information Systems (GIS) Mapping of Environmental Samples across College Campuses

    ERIC Educational Resources Information Center

    Purvis-Roberts, Kathleen L.; Moeur, Harriet P.; Zanella, Andrew

    2007-01-01

    In this laboratory experiment, students take environmental samples at various locations around the college campuses, take geospatial coordinates with a global position systems (GPS) unit, and map their results on a geo-referenced campus map with geographical information systems (GIS) software. Nitrogen dioxide air pollution sampling is used as an…

  16. Ultra-Low Background Measurements Of Decayed Aerosol Filters

    NASA Astrophysics Data System (ADS)

    Miley, H.

    2009-04-01

    To experimentally evaluate the opportunity to apply ultra-low background measurement methods to samples collected, for instance, by the Comprehensive Test Ban Treaty International Monitoring System (IMS), aerosol samples collected on filter media were measured using HPGe spectrometers of varying low-background technology approaches. In this way, realistic estimates of the impact of low-background methodology can be assessed on the Minimum Detectable Activities obtained in systems such as the IMS. The current measurement requirement of stations in the IMS is 30 microBq per cubic meter of air for 140Ba, or about 106 fissions per daily sample. Importantly, this is for a fresh aerosol filter. Decay varying form 3 days to one week reduce the intrinsic background from radon daughters in the sample. Computational estimates of the improvement factor for these decayed filters for underground-based HPGe in clean shielding materials are orders of magnitude less, even when the decay of the isotopes of interest is included.

  17. Assessment of ambient background concentrations of elements in soil using combined survey and open-source data.

    PubMed

    Mikkonen, Hannah G; Clarke, Bradley O; Dasika, Raghava; Wallis, Christian J; Reichman, Suzie M

    2017-02-15

    Understanding ambient background concentrations in soil, at a local scale, is an essential part of environmental risk assessment. Where high resolution geochemical soil surveys have not been undertaken, soil data from alternative sources, such as environmental site assessment reports, can be used to support an understanding of ambient background conditions. Concentrations of metals/metalloids (As, Mn, Ni, Pb and Zn) were extracted from open-source environmental site assessment reports, for soils derived from the Newer Volcanics basalt, of Melbourne, Victoria, Australia. A manual screening method was applied to remove samples that were indicated to be contaminated by point sources and hence not representative of ambient background conditions. The manual screening approach was validated by comparison to data from a targeted background soil survey. Statistical methods for exclusion of contaminated samples from background soil datasets were compared to the manual screening method. The statistical methods tested included the Median plus Two Median Absolute Deviations, the upper whisker of a normal and log transformed Tukey boxplot, the point of inflection on a cumulative frequency plot and the 95th percentile. We have demonstrated that where anomalous sample results cannot be screened using site information, the Median plus Two Median Absolute Deviations is a conservative method for derivation of ambient background upper concentration limits (i.e. expected maximums). The upper whisker of a boxplot and the point of inflection on a cumulative frequency plot, were also considered adequate methods for deriving ambient background upper concentration limits, where the percentage of contaminated samples is <25%. Median ambient background concentrations of metals/metalloids in the Newer Volcanic soils of Melbourne were comparable to ambient background concentrations in Europe and the United States, except for Ni, which was naturally enriched in the basalt-derived soils of

  18. Theory of choice in bandit, information sampling and foraging tasks.

    PubMed

    Averbeck, Bruno B

    2015-03-01

    Decision making has been studied with a wide array of tasks. Here we examine the theoretical structure of bandit, information sampling and foraging tasks. These tasks move beyond tasks where the choice in the current trial does not affect future expected rewards. We have modeled these tasks using Markov decision processes (MDPs). MDPs provide a general framework for modeling tasks in which decisions affect the information on which future choices will be made. Under the assumption that agents are maximizing expected rewards, MDPs provide normative solutions. We find that all three classes of tasks pose choices among actions which trade-off immediate and future expected rewards. The tasks drive these trade-offs in unique ways, however. For bandit and information sampling tasks, increasing uncertainty or the time horizon shifts value to actions that pay-off in the future. Correspondingly, decreasing uncertainty increases the relative value of actions that pay-off immediately. For foraging tasks the time-horizon plays the dominant role, as choices do not affect future uncertainty in these tasks.

  19. Mathematical background and attitudes toward statistics in a sample of Spanish college students.

    PubMed

    Carmona, José; Martínez, Rafael J; Sánchez, Manuel

    2005-08-01

    To examine the relation of mathematical background and initial attitudes toward statistics of Spanish college students in social sciences the Survey of Attitudes Toward Statistics was given to 827 students. Multivariate analyses tested the effects of two indicators of mathematical background (amount of exposure and achievement in previous courses) on the four subscales. Analysis suggested grades in previous courses are more related to initial attitudes toward statistics than the number of mathematics courses taken. Mathematical background was related with students' affective responses to statistics but not with their valuing of statistics. Implications of possible research are discussed.

  20. Gamma-Ray Background Variability in Mobile Detectors

    NASA Astrophysics Data System (ADS)

    Aucott, Timothy John

    Gamma-ray background radiation significantly reduces detection sensitivity when searching for radioactive sources in the field, such as in wide-area searches for homeland security applications. Mobile detector systems in particular must contend with a variable background that is not necessarily known or even measurable a priori. This work will present measurements of the spatial and temporal variability of the background, with the goal of merging gamma-ray detection, spectroscopy, and imaging with contextual information--a "nuclear street view" of the ubiquitous background radiation. The gamma-ray background originates from a variety of sources, both natural and anthropogenic. The dominant sources in the field are the primordial isotopes potassium-40, uranium-238, and thorium-232, as well as their decay daughters. In addition to the natural background, many artificially-created isotopes are used for industrial or medical purposes, and contamination from fission products can be found in many environments. Regardless of origin, these backgrounds will reduce detection sensitivity by adding both statistical as well as systematic uncertainty. In particular, large detector arrays will be limited by the systematic uncertainty in the background and will suffer from a high rate of false alarms. The goal of this work is to provide a comprehensive characterization of the gamma-ray background and its variability in order to improve detection sensitivity and evaluate the performance of mobile detectors in the field. Large quantities of data are measured in order to study their performance at very low false alarm rates. Two different approaches, spectroscopy and imaging, are compared in a controlled study in the presence of this measured background. Furthermore, there is additional information that can be gained by correlating the gamma-ray data with contextual data streams (such as cameras and global positioning systems) in order to reduce the variability in the background

  1. Being an Informed Consumer of Health Information and Assessment of Electronic Health Literacy in a National Sample of Internet Users: Validity and Reliability of the e-HLS Instrument

    PubMed Central

    Yeatts, Dale; Hughes, Susan; Hudson, Cassie; Bell, Valarie

    2016-01-01

    Background The Internet, with its capacity to provide information that transcends time and space barriers, continues to transform how people find and apply information to their own lives. With the current explosion in electronic sources of health information, including thousands of websites and hundreds of mobile phone health apps, electronic health literacy is gaining an increasing prominence in health and medical research. An important dimension of electronic health literacy is the ability to appraise the quality of information that will facilitate everyday health care decisions. Health information seekers explore their care options by gathering information from health websites, blogs, Web-based forums, social networking websites, and advertisements, despite the fact that information quality on the Internet varies greatly. Nonetheless, research has lagged behind in establishing multidimensional instruments, in part due to the evolving construct of health literacy itself. Objective The purpose of this study was to examine psychometric properties of a new electronic health literacy (ehealth literacy) measure in a national sample of Internet users with specific attention to older users. Our paper is motivated by the fact that ehealth literacy is an underinvestigated area of inquiry. Methods Our sample was drawn from a panel of more than 55,000 participants maintained by Knowledge Networks, the largest national probability-based research panel for Web-based surveys. We examined the factor structure of a 19-item electronic Health Literacy Scale (e-HLS) through exploratory factor analysis (EFA) and confirmatory factor analysis, internal consistency reliability, and construct validity on sample of adults (n=710) and a subsample of older adults (n=194). The AMOS graphics program 21.0 was used to construct a measurement model, linking latent factors obtained from EFA with 19 indicators to determine whether this factor structure achieved a good fit with our entire sample

  2. Discrimination against Students with Foreign Backgrounds: Evidence from Grading in Swedish Public High Schools

    ERIC Educational Resources Information Center

    Hinnerich, Bjorn Tyrefors; Höglin, Erik; Johannesson, Magnus

    2015-01-01

    We rigorously test for discrimination against students with foreign backgrounds in high school grading in Sweden. We analyse a random sample of national tests in the Swedish language graded both non-blindly by the student's own teacher and blindly without any identifying information. The increase in the test score due to non-blind grading is…

  3. Urban Background Study Webinar

    EPA Pesticide Factsheets

    This webinar presented the methodology developed for collecting a city-wide or urban area background data set, general results of southeastern cities data collected to date, and a case study that used this sampling method.

  4. Identification of 210Pb and 210Po in the bulk of copper samples with a low-background alpha particle counter

    NASA Astrophysics Data System (ADS)

    Abe, K.; Hiraide, K.; Ichimura, K.; Kishimoto, Y.; Kobayashi, K.; Kobayashi, M.; Moriyama, S.; Nakahata, M.; Norita, T.; Ogawa, H.; Sato, K.; Sekiya, H.; Takachio, O.; Takeda, A.; Tasaka, S.; Yamashita, M.; Yang, B. S.; Kim, N. Y.; Kim, Y. D.; Itow, Y.; Kanzawa, K.; Kegasa, R.; Masuda, K.; Takiya, H.; Fushimi, K.; Kanzaki, G.; Martens, K.; Suzuki, Y.; Xu, B. D.; Fujita, R.; Hosokawa, K.; Miuchi, K.; Oka, N.; Takeuchi, Y.; Kim, Y. H.; Lee, K. B.; Lee, M. K.; Fukuda, Y.; Miyasaka, M.; Nishijima, K.; Nakamura, S.

    2018-03-01

    We established a method to assay 210Pb and 210Po contaminations in the bulk of copper samples using a low-background alpha particle counter. The achieved sensitivity for the 210Pb and 210Po contaminations reaches a few mBq/kg. Due to this high sensitivity, the 210Pb and 210Po contaminations in oxygen free copper bulk were identified and measured for the first time. The 210Pb contaminations of our oxygen free copper samples were 17-40 mBq/kg. Based on our investigation of copper samples in each production step, the 210Pb in oxygen free copper was understood to be a small residual of an electrolysis process. This method to measure bulk contaminations of 210Pb and 210Po could be applied to other materials.

  5. Identification of 210Pb and 210Po in the bulk of copper samples with a low-background alpha particle counter

    NASA Astrophysics Data System (ADS)

    Kobayashi, Kazuyoshi

    2018-01-01

    We established a method to assay 210Pb and 210Po contaminations in the bulk of copper samples using a low-background alpha particle counter. The achieved sensitivity for the 210Pb and 210Po contaminations reaches a few mBq/kg. Due to this high sensitivity, the 210Pb and 210Po contaminations in oxygen free copper bulk were identified and measured for the first time. The 210Pb contaminations of our oxygen free copper samples were 17-40 mBq/kg. Based on our investigation of copper samples in each production step, the 210Pb in oxygen free copper was understood to be a small residual of an electrolysis process. This method to measure bulk contaminations of 210Pb and 210Po could be applied to other materials.

  6. The EnzymeTracker: an open-source laboratory information management system for sample tracking

    PubMed Central

    2012-01-01

    Background In many laboratories, researchers store experimental data on their own workstation using spreadsheets. However, this approach poses a number of problems, ranging from sharing issues to inefficient data-mining. Standard spreadsheets are also error-prone, as data do not undergo any validation process. To overcome spreadsheets inherent limitations, a number of proprietary systems have been developed, which laboratories need to pay expensive license fees for. Those costs are usually prohibitive for most laboratories and prevent scientists from benefiting from more sophisticated data management systems. Results In this paper, we propose the EnzymeTracker, a web-based laboratory information management system for sample tracking, as an open-source and flexible alternative that aims at facilitating entry, mining and sharing of experimental biological data. The EnzymeTracker features online spreadsheets and tools for monitoring numerous experiments conducted by several collaborators to identify and characterize samples. It also provides libraries of shared data such as protocols, and administration tools for data access control using OpenID and user/team management. Our system relies on a database management system for efficient data indexing and management and a user-friendly AJAX interface that can be accessed over the Internet. The EnzymeTracker facilitates data entry by dynamically suggesting entries and providing smart data-mining tools to effectively retrieve data. Our system features a number of tools to visualize and annotate experimental data, and export highly customizable reports. It also supports QR matrix barcoding to facilitate sample tracking. Conclusions The EnzymeTracker was designed to be easy to use and offers many benefits over spreadsheets, thus presenting the characteristics required to facilitate acceptance by the scientific community. It has been successfully used for 20 months on a daily basis by over 50 scientists. The EnzymeTracker is

  7. Illuminating the Background: Topics in Cosmic Microwave Background Polarization Research

    NASA Astrophysics Data System (ADS)

    Miller, Nathan J.

    The cosmic microwave background provides a wealth of information about the origin and history of the universe. The statistics of the anisotropy and the polarization of the cosmic microwave background, among other things, can tell us about the distribution of matter, the redshift of reionization, and the nature of the primordial uctuations. From the lensing of cosmic microwave background due to intervening matter, we can extract information about neutrinos and the equation of state of dark energy. A measurement of the large angular scale B-mode polarization has been called the "smoking gun" of in ation, a theory that describes a possible early rapid expansion of the universe. The focus of current experiments is to measure this B-mode polarization, while several experiments, such as POLARBEAR, are also looking to measure the lensing of the cosmic microwave background. This dissertation will discuss several different topics in cosmic microwave background polarization research. I will make predictions for future experiments and I will also show analysis for two current experiments, POLARBEAR and BICEP. I will show how beam systematics affect the measurement of cosmological parameters and how well we must limit these systematics in order to get unbiased constraints on cosmological parameters for future experiments. I will discuss a novel way of using the temperature-polarization cross correlation to constrain the amount of inflationary gravitational waves. Through Markov Chain Monte Carlo methods, I will determine how well future experiments will be able to constrain the neutrino masses and their degeneracy parameters. I will show results from current data analysis and calibration being done on the Cedar Flat deployment for the POLARBEAR experiment which is currently being constructed in the Atacama desert in Chile. Finally, I will analyze the claim of detection of cosmological birefringence in the BICEP data and show that there is reason to believe it is due to

  8. Strategies for informed sample size reduction in adaptive controlled clinical trials

    NASA Astrophysics Data System (ADS)

    Arandjelović, Ognjen

    2017-12-01

    Clinical trial adaptation refers to any adjustment of the trial protocol after the onset of the trial. The main goal is to make the process of introducing new medical interventions to patients more efficient. The principal challenge, which is an outstanding research problem, is to be found in the question of how adaptation should be performed so as to minimize the chance of distorting the outcome of the trial. In this paper, we propose a novel method for achieving this. Unlike most of the previously published work, our approach focuses on trial adaptation by sample size adjustment, i.e. by reducing the number of trial participants in a statistically informed manner. Our key idea is to select the sample subset for removal in a manner which minimizes the associated loss of information. We formalize this notion and describe three algorithms which approach the problem in different ways, respectively, using (i) repeated random draws, (ii) a genetic algorithm, and (iii) what we term pair-wise sample compatibilities. Experiments on simulated data demonstrate the effectiveness of all three approaches, with a consistently superior performance exhibited by the pair-wise sample compatibilities-based method.

  9. Information Content of the Near-Field I: Two-Dimensional Samples

    NASA Technical Reports Server (NTRS)

    Frazin, Richard A.; Fischer, David G.; Carney, P. Scott

    2004-01-01

    Limits on the effective resolution of many optical near-field experiments are investigated. The results are applicable to variants of total-internal-reflection microscopy (TIRM), photon-scanning-tunneling microscopy (PSTM), and near-field-scanning-optical microscopy (NSOM) in which the sample is weakly scattering and the direction of illumination may be controlled. Analytical expressions for the variance of the estimate of the complex susceptibility of an unknown two-dimensional object as a function of spatial frequency are obtained for Gaussian and Poisson noise models, and a model-independent measure is examined. The results are used to explore the transition from near-zone to far-zone detection. It is demonstrated that the information content of the measurements made at a distance of even one wavelength away from the sample is already not much different from the information content of the far field. Copyright 2004 Optical Society of America

  10. Evaluation of Autism-Related Health Information on the Web

    ERIC Educational Resources Information Center

    Grant, Nicole; Rodger, Sylvia; Hoffmann, Tammy

    2015-01-01

    Background: The Internet is a frequently accessed source of information for parents of a child with autism. To help parents make informed decisions about treatment options, websites should contain accurate information. This study aimed to evaluate the quality of information in a sample of autism-relevant websites. Materials and Methods:…

  11. 77 FR 38323 - Proposed Extension of Existing Information Collection; Respirable Coal Mine Dust Sampling

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...-9440 (voice); or 202-693-9441 (facsimile). SUPPLEMENTARY INFORMATION: I. Background The title of the..., silicosis, and chronic bronchitis, known collectively as ``black lung.'' These diseases are debilitating and... dust levels since 1970 and, consequently, the prevalence rate of black lung among coal miners, severe...

  12. Introduction of the identification, situation, background, assessment, recommendations tool to improve the quality of information transfer during medical handover in intensive care.

    PubMed

    Ramasubbu, Benjamin; Stewart, Emma; Spiritoso, Rosalba

    2017-02-01

    To audit the quality and safety of the current doctor-to-doctor handover of patient information in our Cardiothoracic Intensive Care Unit. If deficient, to implement a validated handover tool to improve the quality of the handover process. In Cycle 1 we observed the verbal handover and reviewed the written handover information transferred for 50 consecutive patients in St George's Hospital Cardiothoracic Intensive Care Unit. For each patient's handover, we assessed whether each section of the Identification, Situation, Background, Assessment, Recommendations tool was used on a scale of 0-2. Zero if no information in that category was transferred, one if the information was partially transferred and two if all relevant information was transferred. Each patient's handover received a score from 0 to 10 and thus, each cycle a total score of 0-500. Following the implementation of the Identification, Situation, Background, Assessment, Recommendations handover tool in our Intensive Care Unit in Cycle 2, we re-observed the handover process for another 50 consecutive patients hence, completing the audit cycle. There was a significant difference between the total scores from Cycle 1 and 2 (263/500 versus 457/500, p < 0.001). The median handover score for Cycle 1 was 5/10 (interquartile range 4-6). The median handover score for Cycle 2 was 9/10 (interquartile range 9-10). Patient handover scores increased significantly between Cycle 1 and 2, U = 13.5, p < 0.001. The introduction of a standardised handover template (Identification, Situation, Background, Assessment, Recommendations tool) has improved the quality and safety of the doctor-to-doctor handover of patient information in our Intensive Care Unit.

  13. Background frequency of Bacillus species at the Canberra Airport: A 12 month study.

    PubMed

    Gahan, Michelle E; Thomas, Rory; Rossi, Rebecca; Nelson, Michelle; Roffey, Paul; Richardson, Michelle M; McNevin, Dennis

    2015-12-01

    Anthrax, caused by Bacillus anthracis, is a naturally occurring disease in Australia. Whilst mainly limited to livestock in grazing regions of Victoria and New South Wales, movement of people, stock and vehicles means B. anthracis could be present outside this region. Of particular interest is the "background" prevalence of B. anthracis at transport hubs including airports. The aim of this study was to determine the background frequency of B. anthracis and the commonly used hoax agent Bacillus thuringiensis at the Canberra Airport over a 12 month period. Samples were collected daily for seven days each month from August 2011-July 2012 and analyzed using species specific real-time polymerase chain reaction. Fourteen samples (of a total of 575) were positive for the B. anthracis PL3 genomic marker, 24 for the cya (pXO1) plasmid marker and five for the capB (pXO2) plasmid marker. Whilst five samples were positive for both PL3 and cya, no samples were positive for all three markers hence there is no evidence to suggest the presence of pathogenic B. anthracis strains. B. anthracis targets were detected primarily in February 2012 and B. thuringiensis peaked in October and November 2011 and again in April and May 2012. This study provides a rapid method to screen for, and differentiate, Bacillus species. Armed with this information investigators will be able to discriminate a "threat" from "background" frequencies should the need arise. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Neighborhood Information Service Centers. Public Library "Information and Referral" Provides Significant New Personal Service to the Individual Library User. A Background Paper for the White House Conference on Library and Information Services.

    ERIC Educational Resources Information Center

    Layne, Elizabeth N.

    This booklet, one of a series of background papers for the White House Conference, presents information and referral services as one of the ways libraries are developing programs to discharge their responsibilities to the public they serve. It details the determination of a woman librarian in Detroit to develop the first comprehensive I&R…

  15. Background sampling and transferability of species distribution model ensembles under climate change

    NASA Astrophysics Data System (ADS)

    Iturbide, Maialen; Bedia, Joaquín; Gutiérrez, José Manuel

    2018-07-01

    Species Distribution Models (SDMs) constitute an important tool to assist decision-making in environmental conservation and planning. A popular application of these models is the projection of species distributions under climate change conditions. Yet there are still a range of methodological SDM factors which limit the transferability of these models, contributing significantly to the overall uncertainty of the resulting projections. An important source of uncertainty often neglected in climate change studies comes from the use of background data (a.k.a. pseudo-absences) for model calibration. Here, we study the sensitivity to pseudo-absence sampling as a determinant factor for SDM stability and transferability under climate change conditions, focusing on European wide projections of Quercus robur as an illustrative case study. We explore the uncertainty in future projections derived from ten pseudo-absence realizations and three popular SDMs (GLM, Random Forest and MARS). The contribution of the pseudo-absence realization to the uncertainty was higher in peripheral regions and clearly differed among the tested SDMs in the whole study domain, being MARS the most sensitive - with projections differing up to a 40% for different realizations - and GLM the most stable. As a result we conclude that parsimonious SDMs are preferable in this context, avoiding complex methods (such as MARS) which may exhibit poor model transferability. Accounting for this new source of SDM-dependent uncertainty is crucial when forming multi-model ensembles to undertake climate change projections.

  16. Evaluating information content of SNPs for sample-tagging in re-sequencing projects.

    PubMed

    Hu, Hao; Liu, Xiang; Jin, Wenfei; Hilger Ropers, H; Wienker, Thomas F

    2015-05-15

    Sample-tagging is designed for identification of accidental sample mix-up, which is a major issue in re-sequencing studies. In this work, we develop a model to measure the information content of SNPs, so that we can optimize a panel of SNPs that approach the maximal information for discrimination. The analysis shows that as low as 60 optimized SNPs can differentiate the individuals in a population as large as the present world, and only 30 optimized SNPs are in practice sufficient in labeling up to 100 thousand individuals. In the simulated populations of 100 thousand individuals, the average Hamming distances, generated by the optimized set of 30 SNPs are larger than 18, and the duality frequency, is lower than 1 in 10 thousand. This strategy of sample discrimination is proved robust in large sample size and different datasets. The optimized sets of SNPs are designed for Whole Exome Sequencing, and a program is provided for SNP selection, allowing for customized SNP numbers and interested genes. The sample-tagging plan based on this framework will improve re-sequencing projects in terms of reliability and cost-effectiveness.

  17. Statistical Analysis Techniques for Small Sample Sizes

    NASA Technical Reports Server (NTRS)

    Navard, S. E.

    1984-01-01

    The small sample sizes problem which is encountered when dealing with analysis of space-flight data is examined. Because of such a amount of data available, careful analyses are essential to extract the maximum amount of information with acceptable accuracy. Statistical analysis of small samples is described. The background material necessary for understanding statistical hypothesis testing is outlined and the various tests which can be done on small samples are explained. Emphasis is on the underlying assumptions of each test and on considerations needed to choose the most appropriate test for a given type of analysis.

  18. Attitudes of the Japanese public and doctors towards use of archived information and samples without informed consent: preliminary findings based on focus group interviews.

    PubMed

    Asai, Atsushi; Ohnishi, Motoki; Nishigaki, Etsuyo; Sekimoto, Miho; Fukuhara, Shunichi; Fukui, Tsuguya

    2002-01-09

    The purpose of this study is to explore laypersons' attitudes toward the use of archived (existing) materials such as medical records and biological samples and to compare them with the attitudes of physicians who are involved in medical research. Three focus group interviews were conducted, in which seven Japanese male members of the general public, seven female members of the general public and seven physicians participated. It was revealed that the lay public expressed diverse attitudes towards the use of archived information and samples without informed consent. Protecting a subject's privacy, maintaining confidentiality, and communicating the outcomes of studies to research subjects were regarded as essential preconditions if researchers were to have access to archived information and samples used for research without the specific informed consent of the subjects who provided the material. Although participating physicians thought that some kind of prior permission from subjects was desirable, they pointed out the difficulties involved in obtaining individual informed consent in each case. The present preliminary study indicates that the lay public and medical professionals may have different attitudes towards the use of archived information and samples without specific informed consent. This hypothesis, however, is derived from our focus groups interviews, and requires validation through research using a larger sample.

  19. Evaluation of Shifted Excitation Raman Difference Spectroscopy and Comparison to Computational Background Correction Methods Applied to Biochemical Raman Spectra.

    PubMed

    Cordero, Eliana; Korinth, Florian; Stiebing, Clara; Krafft, Christoph; Schie, Iwan W; Popp, Jürgen

    2017-07-27

    Raman spectroscopy provides label-free biochemical information from tissue samples without complicated sample preparation. The clinical capability of Raman spectroscopy has been demonstrated in a wide range of in vitro and in vivo applications. However, a challenge for in vivo applications is the simultaneous excitation of auto-fluorescence in the majority of tissues of interest, such as liver, bladder, brain, and others. Raman bands are then superimposed on a fluorescence background, which can be several orders of magnitude larger than the Raman signal. To eliminate the disturbing fluorescence background, several approaches are available. Among instrumentational methods shifted excitation Raman difference spectroscopy (SERDS) has been widely applied and studied. Similarly, computational techniques, for instance extended multiplicative scatter correction (EMSC), have also been employed to remove undesired background contributions. Here, we present a theoretical and experimental evaluation and comparison of fluorescence background removal approaches for Raman spectra based on SERDS and EMSC.

  20. Executive functions, information sampling, and decision making in narcolepsy with cataplexy.

    PubMed

    Delazer, Margarete; Högl, Birgit; Zamarian, Laura; Wenter, Johanna; Gschliesser, Viola; Ehrmann, Laura; Brandauer, Elisabeth; Cevikkol, Zehra; Frauscher, Birgit

    2011-07-01

    Narcolepsy with cataplexy (NC) affects neurotransmitter systems regulating emotions and cognitive functions. This study aimed to assess executive functions, information sampling, reward processing, and decision making in NC. Twenty-one NC patients and 58 healthy participants performed an extensive neuropsychological test battery. NC patients scored as controls in executive function tasks assessing set shifting, reversal learning, working memory, and planning. Group differences appeared in a task measuring information sampling and reward sensitivity. NC patients gathered less information, tolerated a higher level of uncertainty, and were less influenced by reward contingencies than controls. NC patients also showed reduced learning in decision making and had significantly lower scores than controls in the fifth block of the IOWA gambling task. No correlations were found with measures of sleepiness. NC patients may achieve high performance in several neuropsychological domains, including executive functions. Specific differences between NC patients and controls highlight the importance of the hypocretin system in reward processing and decision making and are in line with previous neuroimaging and neurophysiological studies. PsycINFO Database Record (c) 2011 APA, all rights reserved.

  1. Background Radioactivity in River and Reservoir Sediments near Los Alamos, New Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S.G.McLin; D.W. Lyons

    2002-05-05

    As part of its continuing Environmental Surveillance Program, regional river and lake-bottom sediments have been collected annually by Los Alamos National Laboratory (the Laboratory) since 1974 and 1979, respectively. These background samples are collected from three drainage basins at ten different river stations and five reservoirs located throughout northern New Mexico and southern Colorado. Radiochemical analyses for these sediments include tritium, strontium-90, cesium-137, total uranium, plutonium-238, plutonium-239,-240, americium-241, gross alpha, gross beta, and gross gamma radioactivity. Detection-limit radioactivity originates as worldwide fallout from aboveground nuclear weapons testing and satellite reentry into Earth's atmosphere. Spatial and temporal variations in individual analytemore » levels originate from atmospheric point-source introductions and natural rate differences in airborne deposition and soil erosion. Background radioactivity values on sediments reflect this variability, and grouped river and reservoir sediment samples show a range of statistical distributions that appear to be analyte dependent. Traditionally, both river and reservoir analyte data were blended together to establish background levels. In this report, however, we group background sediment data according to two criteria. These include sediment source (either river or reservoir sediments) and station location relative to the Laboratory (either upstream or downstream). These grouped data are statistically evaluated through 1997, and background radioactivity values are established for individual analytes in upstream river and reservoir sediments. This information may be used to establish the existence and areal extent of trace-level environmental contamination resulting from historical Laboratory research activities since the early 1940s.« less

  2. Foregrounding the Background.

    ERIC Educational Resources Information Center

    Robbins, Bruce

    1998-01-01

    Argues that when introductory activities to the classics begin with background information, it can upstage or confine the life of the story, and shows little faith in the students as readers or in the literature itself. Suggests sometimes letting the literature begin, and then helping students make sense of it. Discusses examples from "To Kill a…

  3. 76 FR 79565 - Management Contracts-Background Investigations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... Management Contracts--Background Investigations AGENCY: National Indian Gaming Commission. ACTION: Notice of... investigation process required for management contracts. The proposed revision may reduce duplication of efforts... to clarify that a management contractor should be required to submit background information when the...

  4. X-Ray Background Survey Spectrometer (XBSS)

    NASA Technical Reports Server (NTRS)

    Sanders, W. T. (Principal Investigator); Paulos, R. J.

    1996-01-01

    The objective of this investigation was to perform a spectral survey of the low energy diffuse X-ray background using the X-ray Background Survey Spectrometer (XBSS) on board the Space Station Freedom (SSF). XBSS obtains spectra of the X-ray diffuse background in the 11-24 A and 44-84 A wavelength intervals over the entire sky with 15 deg spatial resolution. These X-rays are almost certainly from a very hot (10(exp 6) K) component of the interstellar medium that is contained in regions occupying a large fraction of the interstellar volume near the Sun. Astrophysical plasmas near 10(exp 6) K are rich in emission lines, and the relative strengths of these lines, besides providing information about the physical conditions of the emitting gas, also provide information about its history and heating mechanisms.

  5. Bullying in German Primary Schools: Gender Differences, Age Trends and Influence of Parents' Migration and Educational Backgrounds

    ERIC Educational Resources Information Center

    von Marees, Nandoli; Petermann, Franz

    2010-01-01

    The study discussed herein assessed the prevalence of bullying and analysed possible predictors for bullying in a sample of urban primary school-age children. Factors considered were students' gender and age differences as well as parents' educational level and migration backgrounds. Using a cross-informant approach (self- and teacher-reports),…

  6. 14 CFR 1203.200 - Background and discussion.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1203.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM NASA Information Security Program § 1203.200 Background and discussion. (a) In establishing a... public inspection of that information that is classified to protect the national security. (b) In...

  7. 14 CFR 1203.200 - Background and discussion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1203.200 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM NASA Information Security Program § 1203.200 Background and discussion. (a) In establishing a... public inspection of that information that is classified to protect the national security. (b) In...

  8. Guided transect sampling - a new design combining prior information and field surveying

    Treesearch

    Anna Ringvall; Goran Stahl; Tomas Lamas

    2000-01-01

    Guided transect sampling is a two-stage sampling design in which prior information is used to guide the field survey in the second stage. In the first stage, broad strips are randomly selected and divided into grid-cells. For each cell a covariate value is estimated from remote sensing data, for example. The covariate is the basis for subsampling of a transect through...

  9. Evaluation of Shifted Excitation Raman Difference Spectroscopy and Comparison to Computational Background Correction Methods Applied to Biochemical Raman Spectra

    PubMed Central

    Cordero, Eliana; Korinth, Florian; Stiebing, Clara; Krafft, Christoph; Schie, Iwan W.; Popp, Jürgen

    2017-01-01

    Raman spectroscopy provides label-free biochemical information from tissue samples without complicated sample preparation. The clinical capability of Raman spectroscopy has been demonstrated in a wide range of in vitro and in vivo applications. However, a challenge for in vivo applications is the simultaneous excitation of auto-fluorescence in the majority of tissues of interest, such as liver, bladder, brain, and others. Raman bands are then superimposed on a fluorescence background, which can be several orders of magnitude larger than the Raman signal. To eliminate the disturbing fluorescence background, several approaches are available. Among instrumentational methods shifted excitation Raman difference spectroscopy (SERDS) has been widely applied and studied. Similarly, computational techniques, for instance extended multiplicative scatter correction (EMSC), have also been employed to remove undesired background contributions. Here, we present a theoretical and experimental evaluation and comparison of fluorescence background removal approaches for Raman spectra based on SERDS and EMSC. PMID:28749450

  10. A quick method based on SIMPLISMA-KPLS for simultaneously selecting outlier samples and informative samples for model standardization in near infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Li, Li-Na; Ma, Chang-Ming; Chang, Ming; Zhang, Ren-Cheng

    2017-12-01

    A novel method based on SIMPLe-to-use Interactive Self-modeling Mixture Analysis (SIMPLISMA) and Kernel Partial Least Square (KPLS), named as SIMPLISMA-KPLS, is proposed in this paper for selection of outlier samples and informative samples simultaneously. It is a quick algorithm used to model standardization (or named as model transfer) in near infrared (NIR) spectroscopy. The NIR experiment data of the corn for analysis of the protein content is introduced to evaluate the proposed method. Piecewise direct standardization (PDS) is employed in model transfer. And the comparison of SIMPLISMA-PDS-KPLS and KS-PDS-KPLS is given in this research by discussion of the prediction accuracy of protein content and calculation speed of each algorithm. The conclusions include that SIMPLISMA-KPLS can be utilized as an alternative sample selection method for model transfer. Although it has similar accuracy to Kennard-Stone (KS), it is different from KS as it employs concentration information in selection program. This means that it ensures analyte information is involved in analysis, and the spectra (X) of the selected samples is interrelated with concentration (y). And it can be used for outlier sample elimination simultaneously by validation of calibration. According to the statistical data results of running time, it is clear that the sample selection process is more rapid when using KPLS. The quick algorithm of SIMPLISMA-KPLS is beneficial to improve the speed of online measurement using NIR spectroscopy.

  11. Background Error Covariance Estimation using Information from a Single Model Trajectory with Application to Ocean Data Assimilation into the GEOS-5 Coupled Model

    NASA Technical Reports Server (NTRS)

    Keppenne, Christian L.; Rienecker, Michele M.; Kovach, Robin M.; Vernieres, Guillaume; Koster, Randal D. (Editor)

    2014-01-01

    An attractive property of ensemble data assimilation methods is that they provide flow dependent background error covariance estimates which can be used to update fields of observed variables as well as fields of unobserved model variables. Two methods to estimate background error covariances are introduced which share the above property with ensemble data assimilation methods but do not involve the integration of multiple model trajectories. Instead, all the necessary covariance information is obtained from a single model integration. The Space Adaptive Forecast error Estimation (SAFE) algorithm estimates error covariances from the spatial distribution of model variables within a single state vector. The Flow Adaptive error Statistics from a Time series (FAST) method constructs an ensemble sampled from a moving window along a model trajectory. SAFE and FAST are applied to the assimilation of Argo temperature profiles into version 4.1 of the Modular Ocean Model (MOM4.1) coupled to the GEOS-5 atmospheric model and to the CICE sea ice model. The results are validated against unassimilated Argo salinity data. They show that SAFE and FAST are competitive with the ensemble optimal interpolation (EnOI) used by the Global Modeling and Assimilation Office (GMAO) to produce its ocean analysis. Because of their reduced cost, SAFE and FAST hold promise for high-resolution data assimilation applications.

  12. Sample processing approach for detection of ricin in surface samples.

    PubMed

    Kane, Staci; Shah, Sanjiv; Erler, Anne Marie; Alfaro, Teneile

    2017-12-01

    With several ricin contamination incidents reported over the past decade, rapid and accurate methods are needed for environmental sample analysis, especially after decontamination. A sample processing method was developed for common surface sampling devices to improve the limit of detection and avoid false negative/positive results for ricin analysis. Potential assay interferents from the sample matrix (bleach residue, sample material, wetting buffer), including reference dust, were tested using a Time-Resolved Fluorescence (TRF) immunoassay. Test results suggested that the sample matrix did not cause the elevated background fluorescence sometimes observed when analyzing post-bleach decontamination samples from ricin incidents. Furthermore, sample particulates (80mg/mL Arizona Test Dust) did not enhance background fluorescence or interfere with ricin detection by TRF. These results suggested that high background fluorescence in this immunoassay could be due to labeled antibody quality and/or quantity issues. Centrifugal ultrafiltration devices were evaluated for ricin concentration as a part of sample processing. Up to 30-fold concentration of ricin was observed by the devices, which serve to remove soluble interferents and could function as the front-end sample processing step to other ricin analytical methods. The procedure has the potential to be used with a broader range of environmental sample types and with other potential interferences and to be followed by other ricin analytical methods, although additional verification studies would be required. Published by Elsevier B.V.

  13. Soudan Low Background Counting Facility (SOLO)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Attisha, Michael; Viveiros, Luiz de; Gaitksell, Richard

    2005-09-08

    The Soudan Low Background Counting Facility (SOLO) has been in operation at the Soudan Mine, MN since March 2003. In the past two years, we have gamma-screened samples for the Majorana, CDMS and XENON experiments. With individual sample exposure times of up to two weeks we have measured sample contamination down to the 0.1 ppb level for 238U / 232Th, and down to the 0.25 ppm level for 40K.

  14. China: Background Notes Series.

    ERIC Educational Resources Information Center

    Reams, Joanne Reppert

    Concise background information on the People's Republic of China is provided. The publication begins with a profile of the country, outlining the people, geography, economy, and membership in international organizations. The bulk of the document then discusses in more detail China's people, geography, history, government, education, economy, and…

  15. Synthesizing Information from Language Samples and Standardized Tests in School-Age Bilingual Assessment

    ERIC Educational Resources Information Center

    Ebert, Kerry Danahy; Pham, Giang

    2017-01-01

    Purpose: Although language samples and standardized tests are regularly used in assessment, few studies provide clinical guidance on how to synthesize information from these testing tools. This study extends previous work on the relations between tests and language samples to a new population--school-age bilingual speakers with primary language…

  16. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

    PubMed

    Corces, M Ryan; Trevino, Alexandro E; Hamilton, Emily G; Greenside, Peyton G; Sinnott-Armstrong, Nicholas A; Vesuna, Sam; Satpathy, Ansuman T; Rubin, Adam J; Montine, Kathleen S; Wu, Beijing; Kathiria, Arwa; Cho, Seung Woo; Mumbach, Maxwell R; Carter, Ava C; Kasowski, Maya; Orloff, Lisa A; Risca, Viviana I; Kundaje, Anshul; Khavari, Paul A; Montine, Thomas J; Greenleaf, William J; Chang, Howard Y

    2017-10-01

    We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content. The Omni-ATAC protocol generates chromatin accessibility profiles from archival frozen tissue samples and 50-μm sections, revealing the activities of disease-associated DNA elements in distinct human brain structures. The Omni-ATAC protocol enables the interrogation of personal regulomes in tissue context and translational studies.

  17. Child Care: State Requirements for Background Checks.

    ERIC Educational Resources Information Center

    Fagnoni, Cynthia

    Background checks involve gathering information from state and federal databases to determine if child care providers have a history of child abuse or other criminal convictions that would make them unacceptable for working with children. Background checks include state criminal history checks, state child abuse registry checks, and Federal Bureau…

  18. Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors.

    PubMed

    Gajewski, Byron J; Mayo, Matthew S

    2006-08-15

    A number of researchers have discussed phase II clinical trials from a Bayesian perspective. A recent article by Mayo and Gajewski focuses on sample size calculations, which they determine by specifying an informative prior distribution and then calculating a posterior probability that the true response will exceed a prespecified target. In this article, we extend these sample size calculations to include a mixture of informative prior distributions. The mixture comes from several sources of information. For example consider information from two (or more) clinicians. The first clinician is pessimistic about the drug and the second clinician is optimistic. We tabulate the results for sample size design using the fact that the simple mixture of Betas is a conjugate family for the Beta- Binomial model. We discuss the theoretical framework for these types of Bayesian designs and show that the Bayesian designs in this paper approximate this theoretical framework. Copyright 2006 John Wiley & Sons, Ltd.

  19. Low Background Counting at LBNL

    DOE PAGES

    Smith, A. R.; Thomas, K. J.; Norman, E. B.; ...

    2015-03-24

    The Low Background Facility (LBF) at Lawrence Berkeley National Laboratory in Berkeley, California provides low background gamma spectroscopy services to a wide array of experiments and projects. The analysis of samples takes place within two unique facilities; locally within a carefully-constructed, low background cave and remotely at an underground location that historically has operated underground in Oroville, CA, but has recently been relocated to the Sanford Underground Research Facility (SURF) in Lead, SD. These facilities provide a variety of gamma spectroscopy services to low background experiments primarily in the form of passive material screening for primordial radioisotopes (U, Th, K)more » or common cosmogenic/anthropogenic products, as well as active screening via Neutron Activation Analysis for specific applications. The LBF also provides hosting services for general R&D testing in low background environments on the surface or underground for background testing of detector systems or similar prototyping. A general overview of the facilities, services, and sensitivities is presented. Recent activities and upgrades will also be presented, such as the completion of a 3π anticoincidence shield at the surface station and environmental monitoring of Fukushima fallout. The LBF is open to any users for counting services or collaboration on a wide variety of experiments and projects.« less

  20. [Study on once sampling quantitation based on information entropy of ISSR amplified bands of Houttuynia cordata].

    PubMed

    Wang, Haiqin; Liu, Wenlong; He, Fuyuan; Chen, Zuohong; Zhang, Xili; Xie, Xianggui; Zeng, Jiaoli; Duan, Xiaopeng

    2012-02-01

    To explore the once sampling quantitation of Houttuynia cordata through its DNA polymorphic bands that carried information entropy, from other form that the expression of traditional Chinese medicine polymorphism, genetic polymorphism, of traditional Chinese medicine. The technique of inter simple sequence repeat (ISSR) was applied to analyze genetic polymorphism of H. cordata samples from the same GAP producing area, the DNA genetic bands were transformed its into the information entropy, and the minimum once sampling quantitation with the mathematical mode was measured. One hundred and thirty-four DNA bands were obtained by using 9 screened ISSR primers to amplify from 46 strains DNA samples of H. cordata from the same GAP, the information entropy was H=0.365 6-0.978 6, and RSD was 14.75%. The once sampling quantitation was W=11.22 kg (863 strains). The "once minimum sampling quantitation" were calculated from the angle of the genetic polymorphism of H. cordata, and a great differences between this volume and the amount from the angle of fingerprint were found.

  1. A remote sensing and geographic information system approach to sampling malaria vector habitats in Chiapas, Mexico

    NASA Astrophysics Data System (ADS)

    Beck, L.; Wood, B.; Whitney, S.; Rossi, R.; Spanner, M.; Rodriguez, M.; Rodriguez-Ramirez, A.; Salute, J.; Legters, L.; Roberts, D.; Rejmankova, E.; Washino, R.

    1993-08-01

    This paper describes a procedure whereby remote sensing and geographic information system (GIS) technologies are used in a sample design to study the habitat of Anopheles albimanus, one of the principle vectors of malaria in Central America. This procedure incorporates Landsat-derived land cover maps with digital elevation and road network data to identify a random selection of larval habitats accessible for field sampling. At the conclusion of the sampling season, the larval counts will be used to determine habitat productivity, and then integrated with information on human settlement to assess where people are at high risk of malaria. This aproach would be appropriate in areas where land cover information is lacking and problems of access constrain field sampling. The use of a GIS also permits other data (such as insecticide spraying data) to the incorporated in the sample design as they arise. This approach would also be pertinent for other tropical vector-borne diseases, particularly where human activities impact disease vector habitat.

  2. Synthesizing Information From Language Samples and Standardized Tests in School-Age Bilingual Assessment

    PubMed Central

    Pham, Giang

    2017-01-01

    Purpose Although language samples and standardized tests are regularly used in assessment, few studies provide clinical guidance on how to synthesize information from these testing tools. This study extends previous work on the relations between tests and language samples to a new population—school-age bilingual speakers with primary language impairment—and considers the clinical implications for bilingual assessment. Method Fifty-one bilingual children with primary language impairment completed narrative language samples and standardized language tests in English and Spanish. Children were separated into younger (ages 5;6 [years;months]–8;11) and older (ages 9;0–11;2) groups. Analysis included correlations with age and partial correlations between language sample measures and test scores in each language. Results Within the younger group, positive correlations with large effect sizes indicated convergence between test scores and microstructural language sample measures in both Spanish and English. There were minimal correlations in the older group for either language. Age related to English but not Spanish measures. Conclusions Tests and language samples complement each other in assessment. Wordless picture-book narratives may be more appropriate for ages 5–8 than for older children. We discuss clinical implications, including a case example of a bilingual child with primary language impairment, to illustrate how to synthesize information from these tools in assessment. PMID:28055056

  3. Spatial inventory integrating raster databases and point sample data. [Geographic Information System for timber inventory

    NASA Technical Reports Server (NTRS)

    Strahler, A. H.; Woodcock, C. E.; Logan, T. L.

    1983-01-01

    A timber inventory of the Eldorado National Forest, located in east-central California, provides an example of the use of a Geographic Information System (GIS) to stratify large areas of land for sampling and the collection of statistical data. The raster-based GIS format of the VICAR/IBIS software system allows simple and rapid tabulation of areas, and facilitates the selection of random locations for ground sampling. Algorithms that simplify the complex spatial pattern of raster-based information, and convert raster format data to strings of coordinate vectors, provide a link to conventional vector-based geographic information systems.

  4. Expected net present value of sample information: from burden to investment.

    PubMed

    Hall, Peter S; Edlin, Richard; Kharroubi, Samer; Gregory, Walter; McCabe, Christopher

    2012-01-01

    The Expected Value of Information Framework has been proposed as a method for identifying when health care technologies should be immediately reimbursed and when any reimbursement should be withheld while awaiting more evidence. This framework assesses the value of obtaining additional evidence to inform a current reimbursement decision. This represents the burden of not having the additional evidence at the time of the decision. However, when deciding whether to reimburse now or await more evidence, decision makers need to know the value of investing in more research to inform a future decision. Assessing this value requires consideration of research costs, research time, and what happens to patients while the research is undertaken and after completion. The investigators describe a development of the calculation of the expected value of sample information that assesses the value of investing in further research, including an only-in-research strategy and an only-with-research strategy.

  5. 77 FR 10508 - Agency Information Collection Activities; Proposed Collection; Comment Request; Background Checks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... Activities; Proposed Collection; Comment Request; Background Checks for Contractor Employees (Renewal) AGENCY... the electronic docket, go to www.regulations.gov . Title: Background Checks for Contractor Employees... consolidated in 40 CFR part 9. Abstract: The EPA uses contractors to perform services throughout the nation...

  6. Multi-talker background and semantic priming effect

    PubMed Central

    Dekerle, Marie; Boulenger, Véronique; Hoen, Michel; Meunier, Fanny

    2014-01-01

    The reported studies have aimed to investigate whether informational masking in a multi-talker background relies on semantic interference between the background and target using an adapted semantic priming paradigm. In 3 experiments, participants were required to perform a lexical decision task on a target item embedded in backgrounds composed of 1–4 voices. These voices were Semantically Consistent (SC) voices (i.e., pronouncing words sharing semantic features with the target) or Semantically Inconsistent (SI) voices (i.e., pronouncing words semantically unrelated to each other and to the target). In the first experiment, backgrounds consisted of 1 or 2 SC voices. One and 2 SI voices were added in Experiments 2 and 3, respectively. The results showed a semantic priming effect only in the conditions where the number of SC voices was greater than the number of SI voices, suggesting that semantic priming depended on prime intelligibility and strategic processes. However, even if backgrounds were composed of 3 or 4 voices, reducing intelligibility, participants were able to recognize words from these backgrounds, although no semantic priming effect on the targets was observed. Overall this finding suggests that informational masking can occur at a semantic level if intelligibility is sufficient. Based on the Effortfulness Hypothesis, we also suggest that when there is an increased difficulty in extracting target signals (caused by a relatively high number of voices in the background), more cognitive resources were allocated to formal processes (i.e., acoustic and phonological), leading to a decrease in available resources for deeper semantic processing of background words, therefore preventing semantic priming from occurring. PMID:25400572

  7. Internal combustion engines for alcohol motor fuels: a compilation of background technical information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blaser, Richard

    1980-11-01

    This compilation, a draft training manual containing technical background information on internal combustion engines and alcohol motor fuel technologies, is presented in 3 parts. The first is a compilation of facts from the state of the art on internal combustion engine fuels and their characteristics and requisites and provides an overview of fuel sources, fuels technology and future projections for availability and alternatives. Part two compiles facts about alcohol chemistry, alcohol identification, production, and use, examines ethanol as spirit and as fuel, and provides an overview of modern evaluation of alcohols as motor fuels and of the characteristics of alcoholmore » fuels. The final section compiles cross references on the handling and combustion of fuels for I.C. engines, presents basic evaluations of events leading to the use of alcohols as motor fuels, reviews current applications of alcohols as motor fuels, describes the formulation of alcohol fuels for engines and engine and fuel handling hardware modifications for using alcohol fuels, and introduces the multifuel engines concept. (LCL)« less

  8. The Effect of Cancer Information Seeking on Perceptions of Cancer Risks, Fatalism, and Worry among a U.S. National Sample

    ERIC Educational Resources Information Center

    Amuta, Ann Oyare; Chen, Xuewei; Mkuu, Rahma

    2017-01-01

    Background: Information seeking is crucial in the health behavior context. Cancer information seeking may play a key role in individuals' perceptions and subsequent health behaviors. Purpose: The purpose of this study is to investigate the influence of cancer information seeking on perceptions of cancer worry, fatalism and risk. Methods: Data from…

  9. Estimating background and threshold nitrate concentrations using probability graphs

    USGS Publications Warehouse

    Panno, S.V.; Kelly, W.R.; Martinsek, A.T.; Hackley, Keith C.

    2006-01-01

    Because of the ubiquitous nature of anthropogenic nitrate (NO 3-) in many parts of the world, determining background concentrations of NO3- in shallow ground water from natural sources is probably impossible in most environments. Present-day background must now include diffuse sources of NO3- such as disruption of soils and oxidation of organic matter, and atmospheric inputs from products of combustion and evaporation of ammonia from fertilizer and livestock waste. Anomalies can be defined as NO3- derived from nitrogen (N) inputs to the environment from anthropogenic activities, including synthetic fertilizers, livestock waste, and septic effluent. Cumulative probability graphs were used to identify threshold concentrations separating background and anomalous NO3-N concentrations and to assist in the determination of sources of N contamination for 232 spring water samples and 200 well water samples from karst aquifers. Thresholds were 0.4, 2.5, and 6.7 mg/L for spring water samples, and 0.1, 2.1, and 17 mg/L for well water samples. The 0.4 and 0.1 mg/L values are assumed to represent thresholds for present-day precipitation. Thresholds at 2.5 and 2.1 mg/L are interpreted to represent present-day background concentrations of NO3-N. The population of spring water samples with concentrations between 2.5 and 6.7 mg/L represents an amalgam of all sources of NO3- in the ground water basins that feed each spring; concentrations >6.7 mg/L were typically samples collected soon after springtime application of synthetic fertilizer. The 17 mg/L threshold (adjusted to 15 mg/L) for well water samples is interpreted as the level above which livestock wastes dominate the N sources. Copyright ?? 2006 The Author(s).

  10. Sampling intraspecific variability in leaf functional traits: Practical suggestions to maximize collected information.

    PubMed

    Petruzzellis, Francesco; Palandrani, Chiara; Savi, Tadeja; Alberti, Roberto; Nardini, Andrea; Bacaro, Giovanni

    2017-12-01

    The choice of the best sampling strategy to capture mean values of functional traits for a species/population, while maintaining information about traits' variability and minimizing the sampling size and effort, is an open issue in functional trait ecology. Intraspecific variability (ITV) of functional traits strongly influences sampling size and effort. However, while adequate information is available about intraspecific variability between individuals (ITV BI ) and among populations (ITV POP ), relatively few studies have analyzed intraspecific variability within individuals (ITV WI ). Here, we provide an analysis of ITV WI of two foliar traits, namely specific leaf area (SLA) and osmotic potential (π), in a population of Quercus ilex L. We assessed the baseline ITV WI level of variation between the two traits and provided the minimum and optimal sampling size in order to take into account ITV WI , comparing sampling optimization outputs with those previously proposed in the literature. Different factors accounted for different amount of variance of the two traits. SLA variance was mostly spread within individuals (43.4% of the total variance), while π variance was mainly spread between individuals (43.2%). Strategies that did not account for all the canopy strata produced mean values not representative of the sampled population. The minimum size to adequately capture the studied functional traits corresponded to 5 leaves taken randomly from 5 individuals, while the most accurate and feasible sampling size was 4 leaves taken randomly from 10 individuals. We demonstrate that the spatial structure of the canopy could significantly affect traits variability. Moreover, different strategies for different traits could be implemented during sampling surveys. We partially confirm sampling sizes previously proposed in the recent literature and encourage future analysis involving different traits.

  11. Mars Sample Handling Protocol Workshop Series

    NASA Technical Reports Server (NTRS)

    Rummel, John D. (Editor); Race, Margaret S. (Editor); Acevedo, Sara (Technical Monitor)

    2000-01-01

    This document is the report resulting from the first workshop of the series on development of the criteria for a Mars sample handling protocol. Workshop 1 was held in Bethesda, Maryland on March 20-22, 2000. This report serves to document the proceedings of Workshop 1; it summarizes relevant background information, provides an overview of the deliberations to date, and helps frame issues that will need further attention or resolution in upcoming workshops. Specific recommendations are not part of this report.

  12. Lewis Information Network (LINK): Background and overview

    NASA Technical Reports Server (NTRS)

    Schulte, Roger R.

    1987-01-01

    The NASA Lewis Research Center supports many research facilities with many isolated buildings, including wind tunnels, test cells, and research laboratories. These facilities are all located on a 350 acre campus adjacent to the Cleveland Hopkins Airport. The function of NASA-Lewis is to do basic and applied research in all areas of aeronautics, fluid mechanics, materials and structures, space propulsion, and energy systems. These functions require a great variety of remote high speed, high volume data communications for computing and interactive graphic capabilities. In addition, new requirements for local distribution of intercenter video teleconferencing and data communications via satellite have developed. To address these and future communications requirements for the next 15 yrs, a project team was organized to design and implement a new high speed communication system that would handle both data and video information in a common lab-wide Local Area Network. The project team selected cable television broadband coaxial cable technology as the communications medium and first installation of in-ground cable began in the summer of 1980. The Lewis Information Network (LINK) became operational in August 1982 and has become the backbone of all data communications and video.

  13. Adaptive sampling of AEM transients

    NASA Astrophysics Data System (ADS)

    Di Massa, Domenico; Florio, Giovanni; Viezzoli, Andrea

    2016-02-01

    This paper focuses on the sampling of the electromagnetic transient as acquired by airborne time-domain electromagnetic (TDEM) systems. Typically, the sampling of the electromagnetic transient is done using a fixed number of gates whose width grows logarithmically (log-gating). The log-gating has two main benefits: improving the signal to noise (S/N) ratio at late times, when the electromagnetic signal has amplitudes equal or lower than the natural background noise, and ensuring a good resolution at the early times. However, as a result of fixed time gates, the conventional log-gating does not consider any geological variations in the surveyed area, nor the possibly varying characteristics of the measured signal. We show, using synthetic models, how a different, flexible sampling scheme can increase the resolution of resistivity models. We propose a new sampling method, which adapts the gating on the base of the slope variations in the electromagnetic (EM) transient. The use of such an alternative sampling scheme aims to get more accurate inverse models by extracting the geoelectrical information from the measured data in an optimal way.

  14. Obelix, a new low-background HPGe at Modane Underground Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loaiza, P.; LAL, Univ. Paris-Sud, CNRS/IN2P3, 91405 Orsay; Brudanin, V.

    An ultra-low background coaxial HPGe detector for gamma-ray spectrometry with a relative efficiency of 160%, corresponding to a 600 cm{sup 3} Ge crystal, was installed at the Laboratoire Souterrain de Modane, France (4800 m.w.e). To reduce the instrinsic detector background, all parts involved in the detector cryostat were selected for their low radioactivity contamination. A shielding, composed of an inner layer of roman lead and an external layer of regular lead was installed, together with a system to reduce the Rn level inside the sample chamber. The shielding was designed to allow the measurement of Marinelli-shaped samples. We present the constructional detailsmore » which lead to a remarkable low detector background of 73 cts/kg·d in [40, 3000] keV. Measured samples showed that sensitivities about 100 μBq/kg in {sup 226}Ra and {sup 228}Th are reached for samples of some kg and 30 days of lifetime.« less

  15. Statistical analyses of the background distribution of groundwater solutes, Los Alamos National Laboratory, New Mexico.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Longmire, Patrick A.; Goff, Fraser; Counce, D. A.

    2004-01-01

    Background or baseline water chemistry data and information are required to distingu ish between contaminated and non-contaminated waters for environmental investigations conducted at Los Alamos National Laboratory (referred to as the Laboratory). The term 'background' refers to natural waters discharged by springs or penetrated by wells that have not been contaminated by LANL or other municipal or industrial activities, and that are representative of groundwater discharging from their respective aquifer material. These investigations are conducted as part of the Environmental Restoration (ER) Project, Groundwater Protection Program (GWPP), Laboratory Surveillance Program, the Hydrogeologic Workplan, and the Site-Wide Environmental Impact Statement (SWEIS).more » This poster provides a comprehensive, validated database of inorganic, organic, stable isotope, and radionuclide analyses of up to 136 groundwater samples collected from 15 baseline springs and wells located in and around Los Alamos National Laboratory, New Mexico. The region considered in this investigation extends from the western edge of the Jemez Mountains eastward to the Rio Grande and from Frijoles Canyon northward to Garcia Canyon. Figure 1 shows the fifteen stations sampled for this investigation. The sampling stations and associated aquifer types are summarized in Table 1.« less

  16. Optimal Sampling to Provide User-Specific Climate Information.

    NASA Astrophysics Data System (ADS)

    Panturat, Suwanna

    The types of weather-related world problems which are of socio-economic importance selected in this study as representative of three different levels of user groups include: (i) a regional problem concerned with air pollution plumes which lead to acid rain in the north eastern United States, (ii) a state-level problem in the form of winter wheat production in Oklahoma, and (iii) an individual-level problem involving reservoir management given errors in rainfall estimation at Lake Ellsworth, upstream from Lawton, Oklahoma. The study is aimed at designing optimal sampling networks which are based on customer value systems and also abstracting from data sets that information which is most cost-effective in reducing the climate-sensitive aspects of a given user problem. Three process models being used in this study to interpret climate variability in terms of the variables of importance to the user comprise: (i) the HEFFTER-SAMSON diffusion model as the climate transfer function for acid rain, (ii) the CERES-MAIZE plant process model for winter wheat production and (iii) the AGEHYD streamflow model selected as "a black box" for reservoir management. A state-of-the-art Non Linear Program (NLP) algorithm for minimizing an objective function is employed to determine the optimal number and location of various sensors. Statistical quantities considered in determining sensor locations including Bayes Risk, the chi-squared value, the probability of the Type I error (alpha) and the probability of the Type II error (beta) and the noncentrality parameter delta^2. Moreover, the number of years required to detect a climate change resulting in a given bushel per acre change in mean wheat production is determined; the number of seasons of observations required to reduce the standard deviation of the error variance of the ambient sulfur dioxide to less than a certain percent of the mean is found; and finally the policy of maintaining pre-storm flood pools at selected levels is

  17. 14 CFR 91.1051 - Pilot safety background check.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Pilot safety background check. 91.1051... Operations Program Management § 91.1051 Pilot safety background check. Within 90 days of an individual beginning service as a pilot, the program manager must request the following information: (a) FAA records...

  18. The Effect of Family Background, University Quality and Educational Mismatch on Wage: An Analysis Using a Young Cohort of Italian Graduates

    ERIC Educational Resources Information Center

    Ordine, Patrizia; Rose, Giuseppe

    2015-01-01

    This paper analyzes the impact of university quality, family background and mismatch on the wages of young Italian graduates. An empirical analysis is undertaken using a representative sample of graduates merged with a dataset containing information on the characteristics of universities. By utilizing quantile regression techniques, some evidence…

  19. Onco-STS: a web-based laboratory information management system for sample and analysis tracking in oncogenomic experiments.

    PubMed

    Gavrielides, Mike; Furney, Simon J; Yates, Tim; Miller, Crispin J; Marais, Richard

    2014-01-01

    Whole genomes, whole exomes and transcriptomes of tumour samples are sequenced routinely to identify the drivers of cancer. The systematic sequencing and analysis of tumour samples, as well other oncogenomic experiments, necessitates the tracking of relevant sample information throughout the investigative process. These meta-data of the sequencing and analysis procedures include information about the samples and projects as well as the sequencing centres, platforms, data locations, results locations, alignments, analysis specifications and further information relevant to the experiments. The current work presents a sample tracking system for oncogenomic studies (Onco-STS) to store these data and make them easily accessible to the researchers who work with the samples. The system is a web application, which includes a database and a front-end web page that allows the remote access, submission and updating of the sample data in the database. The web application development programming framework Grails was used for the development and implementation of the system. The resulting Onco-STS solution is efficient, secure and easy to use and is intended to replace the manual data handling of text records. Onco-STS allows simultaneous remote access to the system making collaboration among researchers more effective. The system stores both information on the samples in oncogenomic studies and details of the analyses conducted on the resulting data. Onco-STS is based on open-source software, is easy to develop and can be modified according to a research group's needs. Hence it is suitable for laboratories that do not require a commercial system.

  20. Importance of background values in assessing the impact of heavy metals in river ecosystems: case study of Tisza River, Serbia.

    PubMed

    Štrbac, Snežana; Kašanin Grubin, Milica; Vasić, Nebojša

    2017-11-30

    The main objective of this paper is to evaluate how a choice of different background values may affect assessing the anthropogenic heavy metal pollution in sediments from Tisza River (Serbia). The second objective of this paper is to underline significance of using geochemical background values when establishing quality criteria for sediment. Enrichment factor (EF), geoaccumulation index (I geo ), pollution load index (PLI), and potential ecological risk index (PERI) were calculated using different background values. Three geochemical (average metal concentrations in continental crust, average metal concentrations in shale, and average metal concentrations in non-contaminated core sediment samples) and two statistical methods (delineation method and principal component analyses) were used for calculating background values. It can be concluded that obtained information of pollution status can be more dependent on the use of background values than the index/factor chosen. The best option to assess the potential river sediment contamination is to compare obtained concentrations of analyzed elements with concentrations of mineralogically and texturally comparable, uncontaminated core sediment samples. Geochemical background values should be taken into account when establishing quality criteria for soils, sediments, and waters. Due to complexity of the local lithology, it is recommended that environmental monitoring and assessment include selection of an appropriate background values to gain understanding of the geochemistry and potential source of pollution in a given environment.

  1. Accessibility and Integrity of Networked Information Collections. Background Paper.

    ERIC Educational Resources Information Center

    Lynch, Clifford A.

    This paper considers questions related to the integrity and accessibility of new electronic information resources. It begins with a review of recent developments in networked information resources and the tools to identify, navigate, and use such resources. An overview is then given of the issues involved in access and integrity questions. Links…

  2. 32 CFR 701.40 - Background.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OFFICIAL RECORDS AVAILABILITY OF DEPARTMENT OF THE NAVY RECORDS AND PUBLICATION OF DEPARTMENT OF THE NAVY DOCUMENTS AFFECTING THE PUBLIC FOIA Fees § 701.40 Background. (a) The DON follows the uniform fee schedule... Freedom of Information Act Fee Schedule and Guidelines. (b) Fees reflect direct costs for search; review...

  3. Alpha Matting with KL-Divergence Based Sparse Sampling.

    PubMed

    Karacan, Levent; Erdem, Aykut; Erdem, Erkut

    2017-06-22

    In this paper, we present a new sampling-based alpha matting approach for the accurate estimation of foreground and background layers of an image. Previous sampling-based methods typically rely on certain heuristics in collecting representative samples from known regions, and thus their performance deteriorates if the underlying assumptions are not satisfied. To alleviate this, we take an entirely new approach and formulate sampling as a sparse subset selection problem where we propose to pick a small set of candidate samples that best explains the unknown pixels. Moreover, we describe a new dissimilarity measure for comparing two samples which is based on KLdivergence between the distributions of features extracted in the vicinity of the samples. The proposed framework is general and could be easily extended to video matting by additionally taking temporal information into account in the sampling process. Evaluation on standard benchmark datasets for image and video matting demonstrates that our approach provides more accurate results compared to the state-of-the-art methods.

  4. Background radioactivity in sediments near Los Alamos, New Mexico.

    PubMed

    McLin, Stephen G

    2004-07-26

    River and reservoir sediments have been collected annually by Los Alamos National Laboratory since 1974 and 1979, respectively. These background samples are collected from five river stations and four reservoirs located throughout northern New Mexico and southern Colorado. Analyses include 3H, 90Sr, 137Cs, total U, 238Pu, 239,240Pu, 241Am, gross alpha, gross beta, and gross gamma radioactivity. Surprisingly, there are no federal or state regulatory standards in the USA that specify how to compute background radioactivity values on sediments. Hence, the sample median (or 0.50 quantile) is proposed for this background because it reflects central data tendency and is distribution-free. Estimates for the upper limit of background radioactivity on river and reservoir sediments are made for sampled analytes using the 0.95 quantile (two-tail). These analyses also show that seven of ten analytes from reservoir sediments are normally distributed, or are normally distributed after a logarithmic or square root transformation. However, only three of ten analytes from river sediments are similarly distributed. In addition, isotope ratios for 137Cs/238Pu, 137Cs/239,240Pu, and 239,240Pu/238Pu from reservoir sediments are independent of clay content, total organic carbon/specific surface area (TOC/SSA) and cation exchange capacity/specific surface area (CEC/SSA) ratios. These TOC/SSA and CEC/SSA ratios reflect sediment organic carbon and surface charge densities that are associated with radionuclide absorption, adsorption, and ion exchange reactions on clay mineral structures. These latter ratio values greatly exceed the availability of background radionuclides in the environment, and insure that measured background levels are a maximum. Since finer-grained reservoir sediments contain larger clay-sized fractions compared to coarser river sediments, they show higher background levels for most analytes. Furthermore, radioactivity values on reservoir sediments have remained

  5. Health inequalities among workers with a foreign background in Sweden: do working conditions matter?

    PubMed

    Dunlavy, Andrea C; Rostila, Mikael

    2013-07-10

    Employment and working conditions are key social determinants of health, yet current information is lacking regarding relationships between foreign background status, working conditions and health among workers in Sweden. This study utilized cross-sectional data from the 2010 Swedish Level of Living Survey (LNU) and the Level of Living Survey for Foreign Born Persons and their Children (LNU-UFB) to assess whether or not health inequalities exist between native Swedish and foreign background workers and if exposure to adverse psychosocial and physical working conditions contributes to the risk for poor health among foreign background workers. A sub-sample of 4,021 employed individuals aged 18-65 was analyzed using logistic regression. Eastern European, Latin American and Other Non-Western workers had an increased risk of both poor self-rated health and mental distress compared to native Swedish workers. Exposure to adverse working conditions only minimally influenced the risk of poor health. Further research should examine workers who are less integrated or who have less secure labor market attachments and also investigate how additional working conditions may influence associations between health and foreign background status.

  6. Health Inequalities among Workers with a Foreign Background in Sweden: Do Working Conditions Matter?

    PubMed Central

    Dunlavy, Andrea C.; Rostila, Mikael

    2013-01-01

    Employment and working conditions are key social determinants of health, yet current information is lacking regarding relationships between foreign background status, working conditions and health among workers in Sweden. This study utilized cross-sectional data from the 2010 Swedish Level of Living Survey (LNU) and the Level of Living Survey for Foreign Born Persons and their Children (LNU-UFB) to assess whether or not health inequalities exist between native Swedish and foreign background workers and if exposure to adverse psychosocial and physical working conditions contributes to the risk for poor health among foreign background workers. A sub-sample of 4,021 employed individuals aged 18–65 was analyzed using logistic regression. Eastern European, Latin American and Other Non-Western workers had an increased risk of both poor self-rated health and mental distress compared to native Swedish workers. Exposure to adverse working conditions only minimally influenced the risk of poor health. Further research should examine workers who are less integrated or who have less secure labor market attachments and also investigate how additional working conditions may influence associations between health and foreign background status. PMID:23846669

  7. 78 FR 5276 - Tribal Background Investigations and Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... industry generally, including ownership interests in those businesses; (7) The name and address of any... temporary and permanent gaming licenses. DATES: Effective Date: February 25, 2013. FOR FURTHER INFORMATION.... Telephone: 202-632-7009. SUPPLEMENTARY INFORMATION: I. Background The Indian Gaming Regulatory Act (IGRA or...

  8. An examination of the RCMAS-2 scores across gender, ethnic background, and age in a large Asian school sample.

    PubMed

    Ang, Rebecca P; Lowe, Patricia A; Yusof, Noradlin

    2011-12-01

    The present study investigated the factor structure, reliability, convergent and discriminant validity, and U.S. norms of the Revised Children's Manifest Anxiety Scale, Second Edition (RCMAS-2; C. R. Reynolds & B. O. Richmond, 2008a) scores in a Singapore sample of 1,618 school-age children and adolescents. Although there were small statistically significant differences in the average RCMAS-2 T scores found across various demographic groupings, on the whole, the U.S. norms appear adequate for use in the Asian Singapore sample. Results from item bias analyses suggested that biased items detected had small effects and were counterbalanced across gender and ethnicity, and hence, their relative impact on test score variation appears to be minimal. Results of factor analyses on the RCMAS-2 scores supported the presence of a large general anxiety factor, the Total Anxiety factor, and the 5-factor structure found in U.S. samples was replicated. Both the large general anxiety factor and the 5-factor solution were invariant across gender and ethnic background. Internal consistency estimates ranged from adequate to good, and 2-week test-retest reliability estimates were comparable to previous studies. Evidence providing support for convergent and discriminant validity of the RCMAS-2 scores was also found. Taken together, findings provide additional cross-cultural evidence of the appropriateness and usefulness of the RCMAS-2 as a measure of anxiety in Asian Singaporean school-age children and adolescents.

  9. Apollo-11 lunar sample information catalogue

    NASA Technical Reports Server (NTRS)

    Kramer, F. E. (Compiler); Twedell, D. B. (Compiler); Walton, W. J. A., Jr. (Compiler)

    1977-01-01

    The Apollo 11 mission is reviewed with emphasis on the collection of lunar samples, their geologic setting, early processing, and preliminary examination. The experience gained during five subsequent missions was applied to obtain physical-chemical data for each sample using photographic and binocular microscope techniques. Topics discussed include: binocular examination procedure; breccia clast dexrriptuons, thin section examinations procedure typical breccia in thin section, typical basalt in thin section, sample histories, and chemical and age data. An index to photographs is included.

  10. DOA-informed source extraction in the presence of competing talkers and background noise

    NASA Astrophysics Data System (ADS)

    Taseska, Maja; Habets, Emanuël A. P.

    2017-12-01

    A desired speech signal in hands-free communication systems is often degraded by noise and interfering speech. Even though the number and locations of the interferers are often unknown in practice, it is justified to assume in certain applications that the direction-of-arrival (DOA) of the desired source is approximately known. Using the known DOA, fixed spatial filters such as the delay-and-sum beamformer can be steered to extract the desired source. However, it is well-known that fixed data-independent spatial filters do not provide sufficient reduction of directional interferers. Instead, the DOA information can be used to estimate the statistics of the desired and the undesired signals and to compute optimal data-dependent spatial filters. One way the DOA is exploited for optimal spatial filtering in the literature, is by designing DOA-based narrowband detectors to determine whether a desired or an undesired signal is dominant at each time-frequency (TF) bin. Subsequently, the statistics of the desired and the undesired signals can be estimated during the TF bins where the respective signal is dominant. In a similar manner, a Gaussian signal model-based detector which does not incorporate DOA information has been used in scenarios where the undesired signal consists of stationary background noise. However, when the undesired signal is non-stationary, resulting for example from interfering speakers, such a Gaussian signal model-based detector is unable to robustly distinguish desired from undesired speech. To this end, we propose a DOA model-based detector to determine the dominant source at each TF bin and estimate the desired and undesired signal statistics. We demonstrate that data-dependent spatial filters that use the statistics estimated by the proposed framework achieve very good undesired signal reduction, even when using only three microphones.

  11. IDENTIFYING POTENTIAL SOURCES OF BACKGROUND CONTAMINATION IN RT-PCR

    EPA Science Inventory

    Extraction of nucleic acids from low biomass samples, such as drinking water, is particularly sensitive to potential background contamination because the contaminating material is minimally diluted by the sample. The presence of bacterial DNA in Taq DNA polymerase is wel...

  12. Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    PubMed Central

    Solanki, Narendra; Rien, Diana; Jaciuch, David; Dongre, Sidhartha Anil; Blanchard, Florence; de Polavieja, Gonzalo G; Hardie, Roger C; Takalo, Jouni

    2017-01-01

    Small fly eyes should not see fine image details. Because flies exhibit saccadic visual behaviors and their compound eyes have relatively few ommatidia (sampling points), their photoreceptors would be expected to generate blurry and coarse retinal images of the world. Here we demonstrate that Drosophila see the world far better than predicted from the classic theories. By using electrophysiological, optical and behavioral assays, we found that R1-R6 photoreceptors’ encoding capacity in time is maximized to fast high-contrast bursts, which resemble their light input during saccadic behaviors. Whilst over space, R1-R6s resolve moving objects at saccadic speeds beyond the predicted motion-blur-limit. Our results show how refractory phototransduction and rapid photomechanical photoreceptor contractions jointly sharpen retinal images of moving objects in space-time, enabling hyperacute vision, and explain how such microsaccadic information sampling exceeds the compound eyes’ optical limits. These discoveries elucidate how acuity depends upon photoreceptor function and eye movements. PMID:28870284

  13. Knowing when to trust a teacher: The contribution of category status and sample composition to young children's judgments of informant trustworthiness.

    PubMed

    Lawson, Chris A

    2018-09-01

    Two experiments examined the extent to which category status influences children's attention to the composition of evidence samples provided by different informants. Children were told about two informants, each of whom presented different samples of evidence, and then were asked to judge which informant they would trust to help them learn something new. The composition of evidence samples was manipulated such that one sample included either a large number (n = 5) or a diverse range of exemplars relative to the other sample, which included either a small number (n = 2) or a homogeneous range of exemplars. Experiment 1 revealed that participants (N = 37; M age = 4.76 years) preferred to place their trust in the informant who presented the large or diverse sample when each informant was labeled "teacher" but exhibited no preference when each informant was labeled "child." Experiment 2 revealed developmental differences in responses when labels and sample composition were pitted against each other. Younger children (n = 32; M age = 3.42 years) consistently trusted the "teacher" regardless of the composition of the sample the informant was said to have provided, whereas older children (n = 30; M age = 5.54 years) consistently trusted the informant who provided the large or diverse sample regardless of whether it was provided by a "teacher" or a "child." These results have important implications for understanding the interplay between children's category knowledge and their evaluation of evidence. Copyright © 2018 Elsevier Inc. All rights reserved.

  14. Computer program documentation user information for the RSO-tape print program (RSOPRNT)

    NASA Technical Reports Server (NTRS)

    Gibbs, P. M. (Principal Investigator)

    1980-01-01

    A user's guide for the RSOPRNT, a TRASYS Master Restart Output Tape (RSO) reader is presented. Background information and sample runstreams, as well as, references, input requirements and options, are included.

  15. Need for information in a representative sample of outpatients with schizophrenia disorders.

    PubMed

    Andrade, Mário César Rezende; Slade, Mike; Bandeira, Marina; Evans-Lacko, Sara; Martin, Denise; Andreoli, Sérgio Baxter

    2018-05-01

    Providing adequate information and involving patients in treatment have become an essential component of mental health care. Despite this, research regarding the extent to which this need has been met in clinical services is still scarce. To investigate the need for information about psychiatric condition and treatment among outpatients with schizophrenia disorders and how this need is associated with service use, adjusting for sociodemographic and clinical characteristics. Need for information about condition and treatment, using the corresponding domain in the Camberwell Assessment of Need (CAN), in a representative sample of 401 schizophrenia outpatients in Santos, Brazil was assessed. Hierarchical logistic regression was used to investigate the association of information as a reported need and as an unmet need with service use variables, adjusting for sociodemographic and clinical characteristics. Need for information was reported by 214 (53.4%) patients, being met in 101 (25.2%) and unmet in 113 (28.2%). Hierarchical regression indicated a significant association of a reported need with higher age of onset, family monitoring medication use last year and lower education level, which was only associated with an unmet need. Information was a commonly reported need and which was often unmet, showing no significant association with service use. Greater attention should be given by mental health services to information provision.

  16. Tritium Concentrations in Environmental Samples and Transpiration Rates from the Vicinity of Mary's Branch Creek and Background Areas, Barnwell, South Carolina, 2007-2009

    USGS Publications Warehouse

    Vroblesky, Don A.; Canova, Judy L.; Bradley, Paul M.; Landmeyer, James E.

    2009-01-01

    Tritium in groundwater from a low-level radioactive waste disposal facility near Barnwell, South Carolina, is discharging to Mary's Branch Creek. The U.S. Geological Survey conducted an investigation from 2007 to 2009 to examine the tritium concentration in trees and air samples near the creek and in background areas, in groundwater near the creek, and in surface water from the creek. Tritium was found in trees near the creek, but not in trees from background areas or from sites unlikely to be in direct root contact with tritium-contaminated groundwater. Tritium was found in groundwater near the creek and in the surface water of the creek. Analysis of tree material has the potential to be a useful tool in locating shallow tritium-contaminated groundwater. A tritium concentration of 1.4 million picocuries per liter was measured in shallow groundwater collected near a tulip poplar located in an area of tritium-contaminated groundwater discharge. Evapotranspiration rates from the tree and tritium concentrations in water extracted from tree cores indicate that during the summer, this tulip poplar may remove more than 17.1 million picocuries of tritium per day from the groundwater that otherwise would discharge to Mary's Branch Creek. Analysis of air samples near the tree showed no evidence that the transpirative release of tritium to the air created a vapor hazard in the forest.

  17. Background modeling for the GERDA experiment

    NASA Astrophysics Data System (ADS)

    Becerici-Schmidt, N.; Gerda Collaboration

    2013-08-01

    The neutrinoless double beta (0νββ) decay experiment GERDA at the LNGS of INFN has started physics data taking in November 2011. This paper presents an analysis aimed at understanding and modeling the observed background energy spectrum, which plays an essential role in searches for a rare signal like 0νββ decay. A very promising preliminary model has been obtained, with the systematic uncertainties still under study. Important information can be deduced from the model such as the expected background and its decomposition in the signal region. According to the model the main background contributions around Qββ come from 214Bi, 228Th, 42K, 60Co and α emitting isotopes in the 226Ra decay chain, with a fraction depending on the assumed source positions.

  18. Multimodal cues provide redundant information for bumblebees when the stimulus is visually salient, but facilitate red target detection in a naturalistic background

    PubMed Central

    Corcobado, Guadalupe; Trillo, Alejandro

    2017-01-01

    Our understanding of how floral visitors integrate visual and olfactory cues when seeking food, and how background complexity affects flower detection is limited. Here, we aimed to understand the use of visual and olfactory information for bumblebees (Bombus terrestris terrestris L.) when seeking flowers in a visually complex background. To explore this issue, we first evaluated the effect of flower colour (red and blue), size (8, 16 and 32 mm), scent (presence or absence) and the amount of training on the foraging strategy of bumblebees (accuracy, search time and flight behaviour), considering the visual complexity of our background, to later explore whether experienced bumblebees, previously trained in the presence of scent, can recall and make use of odour information when foraging in the presence of novel visual stimuli carrying a familiar scent. Of all the variables analysed, flower colour had the strongest effect on the foraging strategy. Bumblebees searching for blue flowers were more accurate, flew faster, followed more direct paths between flowers and needed less time to find them, than bumblebees searching for red flowers. In turn, training and the presence of odour helped bees to find inconspicuous (red) flowers. When bees foraged on red flowers, search time increased with flower size; but search time was independent of flower size when bees foraged on blue flowers. Previous experience with floral scent enhances the capacity of detection of a novel colour carrying a familiar scent, probably by elemental association influencing attention. PMID:28898287

  19. Capture and exploration of sample quality data to inform and improve the management of a screening collection.

    PubMed

    Charles, Isabel; Sinclair, Ian; Addison, Daniel H

    2014-04-01

    A new approach to the storage, processing, and interrogation of the quality data for screening samples has improved analytical throughput and confidence and enhanced the opportunities for learning from the accumulating records. The approach has entailed the design, development, and implementation of a database-oriented system, capturing information from the liquid chromatography-mass spectrometry capabilities used for assessing the integrity of samples in AstraZeneca's screening collection. A Web application has been developed to enable the visualization and interactive annotation of the analytical data, monitor the current sample queue, and report the throughput rate. Sample purity and identity are certified automatically on the chromatographic peaks of interest if predetermined thresholds are reached on key parameters. Using information extracted in parallel from the compound registration and container inventory databases, the chromatographic and spectroscopic profiles for each vessel are linked to the sample structures and storage histories. A search engine facilitates the direct comparison of results for multiple vessels of the same or similar compounds, for single vessels analyzed at different time points, or for vessels related by their origin or process flow. Access to this network of information has provided a deeper understanding of the multiple factors contributing to sample quality assurance.

  20. Background photobleaching in raman spectra of aqueous solutions of plant toxins

    NASA Astrophysics Data System (ADS)

    Brandt, Nikolai N.; Chikishev, Andrey Y.; Tonevitsky, Alexander G.

    2002-05-01

    Kinetics of background photobleaching in Raman spectra of aqueous solutions of ricin, ricin agglutinin and ricin binding subunit were measured. It was found that the spectrum of Raman background changes upon laser irradiation. Background intensity is lower for the samples with lower molecular weight. Photobleaching is characterized by oscillations in the multi exponentially decaying intensity.

  1. Optimal sampling with prior information of the image geometry in microfluidic MRI.

    PubMed

    Han, S H; Cho, H; Paulsen, J L

    2015-03-01

    Recent advances in MRI acquisition for microscopic flows enable unprecedented sensitivity and speed in a portable NMR/MRI microfluidic analysis platform. However, the application of MRI to microfluidics usually suffers from prolonged acquisition times owing to the combination of the required high resolution and wide field of view necessary to resolve details within microfluidic channels. When prior knowledge of the image geometry is available as a binarized image, such as for microfluidic MRI, it is possible to reduce sampling requirements by incorporating this information into the reconstruction algorithm. The current approach to the design of the partial weighted random sampling schemes is to bias toward the high signal energy portions of the binarized image geometry after Fourier transformation (i.e. in its k-space representation). Although this sampling prescription is frequently effective, it can be far from optimal in certain limiting cases, such as for a 1D channel, or more generally yield inefficient sampling schemes at low degrees of sub-sampling. This work explores the tradeoff between signal acquisition and incoherent sampling on image reconstruction quality given prior knowledge of the image geometry for weighted random sampling schemes, finding that optimal distribution is not robustly determined by maximizing the acquired signal but from interpreting its marginal change with respect to the sub-sampling rate. We develop a corresponding sampling design methodology that deterministically yields a near optimal sampling distribution for image reconstructions incorporating knowledge of the image geometry. The technique robustly identifies optimal weighted random sampling schemes and provides improved reconstruction fidelity for multiple 1D and 2D images, when compared to prior techniques for sampling optimization given knowledge of the image geometry. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. 40 CFR 1065.805 - Sampling system.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Sampling system. 1065.805 Section 1065.805 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... background samples for correcting dilution air for background concentrations of alcohols and carbonyls. (c...

  3. 40 CFR 1065.805 - Sampling system.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Sampling system. 1065.805 Section 1065.805 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... background samples for correcting dilution air for background concentrations of alcohols and carbonyls. (c...

  4. 40 CFR 1065.805 - Sampling system.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Sampling system. 1065.805 Section 1065.805 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... background samples for correcting dilution air for background concentrations of alcohols and carbonyls. (c...

  5. Bayesian Analysis of the Power Spectrum of the Cosmic Microwave Background

    NASA Technical Reports Server (NTRS)

    Jewell, Jeffrey B.; Eriksen, H. K.; O'Dwyer, I. J.; Wandelt, B. D.

    2005-01-01

    There is a wealth of cosmological information encoded in the spatial power spectrum of temperature anisotropies of the cosmic microwave background. The sky, when viewed in the microwave, is very uniform, with a nearly perfect blackbody spectrum at 2.7 degrees. Very small amplitude brightness fluctuations (to one part in a million!!) trace small density perturbations in the early universe (roughly 300,000 years after the Big Bang), which later grow through gravitational instability to the large-scale structure seen in redshift surveys... In this talk, I will discuss a Bayesian formulation of this problem; discuss a Gibbs sampling approach to numerically sampling from the Bayesian posterior, and the application of this approach to the first-year data from the Wilkinson Microwave Anisotropy Probe. I will also comment on recent algorithmic developments for this approach to be tractable for the even more massive data set to be returned from the Planck satellite.

  6. Low-background germanium radioassay for the MAJORANA Collaboration

    NASA Astrophysics Data System (ADS)

    Trimble, James E., Jr.

    The focus of the MAJORANA COLLABORATION is the search for nuclear neutrinoless double beta decay. If discovered, this process would prove that the neutrino is its own anti-particle, or a M AJORANA particle. Being constructed at the Sanford Underground Research Facility, the MAJORANA DEMONSTRATOR aims to show that a background rate of 3 counts per region of interest (ROI) per tonne per year in the 4 keV ROI surrounding the 2039-keV Q-value energy of 76Ge is achievable and to demonstrate the technological feasibility of building a tonne-scale Ge-based experiment. Because of the rare nature of this process, detectors in the system must be isolated from ionizing radiation backgrounds as much as possible. This involved building the system with materials containing very low levels of naturally- occurring and anthropogenic radioactive isotopes at a deep underground site. In order to measure the levels of radioactive contamination in some components, the Majorana Demonstrator uses a low background counting facility managed by the Experimental Nuclear and Astroparticle Physics (ENAP) group at UNC. The UNC low background counting (LBC) facility is located at the Kimballton Underground Research Facility (KURF) located in Ripplemead, VA. The facility was used for a neutron activation analysis of samples of polytetrafluoroethylene (PTFE) and fluorinated ethylene propylene (FEP) tubing intended for use in the Demonstrator. Calculated initial activity limits (90% C.L.) of 238U and 232Th in the 0.002-in PTFE samples were 7.6 ppt and 5.1 ppt, respectively. The same limits in the FEP tubing sample were 150 ppt and 45 ppt, respectively. The UNC LBC was also used to gamma-assay a modified stainless steel flange to be used as a vacuum feedthrough. Trace activities of both 238U and 232Th were found in the sample, but all were orders of magnitude below the acceptable threshold for the Majorana experiment. Also discussed is a proposed next generation ultra-low background system designed

  7. The effect of sterilization on biological, organic geochemical and morphological information in natural samples

    NASA Technical Reports Server (NTRS)

    Hochstein, L. I.; Kvenvolden, K. A.; Philpott, D. E.

    1974-01-01

    The loss of biological, organic geochemical, and morphological science information that may occur should a Mars surface sample be sterilized prior to return to earth is examined. Results of experimental studies are summarized.

  8. Can one measure the Cosmic Neutrino Background?

    NASA Astrophysics Data System (ADS)

    Faessler, Amand; Hodák, Rastislav; Kovalenko, Sergey; Šimkovic, Fedor

    The Cosmic Microwave Background (CMB) yields information about our Universe at around 380,000 years after the Big Bang (BB). Due to the weak interaction of the neutrinos with matter, the Cosmic Neutrino Background (CNB) should give information about a much earlier time of our Universe, around one second after the BB. Probably, the most promising method to “see” the CNB is the capture of the electron neutrinos from the Background by Tritium, which then decays into 3He and an electron with the energy of the the Q-value = 18.562keV plus the electron neutrino rest mass. The “KArlsruhe TRItium Neutrino” (KATRIN) experiment, which is in preparation, seems presently the most sensitive proposed method for measuring the electron antineutrino mass. At the same time, KATRIN can also look by the reaction νe(˜ 1.95K) +3H →3He + e-(Q = 18.6keV + m νec2). The capture of the Cosmic Background Neutrinos (CNB) should show in the electron spectrum as a peak by the electron neutrino rest mass above Q. Here, the possibility to see the CNB with KATRIN is studied. A detection of the CNB by KATRIN seems not to be possible at the moment. But KATRIN should be able to determine an upper limit for the local electron neutrino density of the CNB.

  9. Can one measure the Cosmic Neutrino Background?

    NASA Astrophysics Data System (ADS)

    Faessler, Amand; Hodák, Rastislav; Kovalenko, Sergey; Šimkovic, Fedor

    The Cosmic Microwave Background (CMB) yields information about our Universe at around 380,000 years after the Big Bang (BB). Due to the weak interaction of the neutrinos with matter, the Cosmic Neutrino Background (CNB) should give information about a much earlier time of our Universe, around one second after the BB. Probably, the most promising method to "see" the CNB is the capture of the electron neutrinos from the Background by Tritium, which then decays into 3He and an electron with the energy of the the Q-value = 18.562 keV plus the electron neutrino rest mass. The "KArlsruhe TRItium Neutrino" (KATRIN) experiment, which is in preparation, seems presently the most sensitive proposed method for measuring the electron antineutrino mass. At the same time, KATRIN can also look by the reaction νe(˜1.95K) + 3H → 3He + e-(Q = 18.6keV + mνec2). The capture of the Cosmic Background Neutrinos (CNB) should show in the electron spectrum as a peak by the electron neutrino rest mass above Q. Here, the possibility to see the CNB with KATRIN is studied. A detection of the CNB by KATRIN seems not to be possible at the moment. But KATRIN should be able to determine an upper limit for the local electron neutrino density of the CNB.

  10. 10 CFR 37.25 - Background investigations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... investigation; and attempt to obtain the information from an alternate source. (b) Grandfathering. (1... 10 Energy 1 2014-01-01 2014-01-01 false Background investigations. 37.25 Section 37.25 Energy NUCLEAR REGULATORY COMMISSION PHYSICAL PROTECTION OF CATEGORY 1 AND CATEGORY 2 QUANTITIES OF RADIOACTIVE...

  11. The EPIC-MOS Particle-Induced Background Spectra

    NASA Technical Reports Server (NTRS)

    Kuntz, K. D.; Sowden, S. L.

    2007-01-01

    In order to analyse diffuse emission that fills the field of view, one must accurately characterize the instrumental backgrounds. For the XMM-Newton EPIC instrument these backgrounds include a temporally variable "quiescent" component. as well as the strongly variable soft proton contamination. We have characterized the spectral and spatial response of the EPIC detectors to these background components and have developed tools to remove these backgrounds from observations. The "quiescent" component was characterized using a combination of the filter-wheel-closed data and a database of unexposed-region data. The soft proton contamination was characterized by differencing images and spectra taken during flared and flare-free intervals. After application of our modeled backgrounds, the differences between independent observations of the same region of "blank sky" are consistent with the statistical uncertainties except when there is clear spectral evidence of solar wind charge exchange emission. Using a large sample of blank sky data, we show that strong magnetospheric SWCX emission requires elevated solar wind fluxes; observations through the densest part of the magnetosheath are not necessarily strongly contaminated with SWCX emission.

  12. On estimating probability of presence from use-availability or presence-background data.

    PubMed

    Phillips, Steven J; Elith, Jane

    2013-06-01

    A fundamental ecological modeling task is to estimate the probability that a species is present in (or uses) a site, conditional on environmental variables. For many species, available data consist of "presence" data (locations where the species [or evidence of it] has been observed), together with "background" data, a random sample of available environmental conditions. Recently published papers disagree on whether probability of presence is identifiable from such presence-background data alone. This paper aims to resolve the disagreement, demonstrating that additional information is required. We defined seven simulated species representing various simple shapes of response to environmental variables (constant, linear, convex, unimodal, S-shaped) and ran five logistic model-fitting methods using 1000 presence samples and 10 000 background samples; the simulations were repeated 100 times. The experiment revealed a stark contrast between two groups of methods: those based on a strong assumption that species' true probability of presence exactly matches a given parametric form had highly variable predictions and much larger RMS error than methods that take population prevalence (the fraction of sites in which the species is present) as an additional parameter. For six species, the former group grossly under- or overestimated probability of presence. The cause was not model structure or choice of link function, because all methods were logistic with linear and, where necessary, quadratic terms. Rather, the experiment demonstrates that an estimate of prevalence is not just helpful, but is necessary (except in special cases) for identifying probability of presence. We therefore advise against use of methods that rely on the strong assumption, due to Lele and Keim (recently advocated by Royle et al.) and Lancaster and Imbens. The methods are fragile, and their strong assumption is unlikely to be true in practice. We emphasize, however, that we are not arguing against

  13. Glycemic Control in a Clinic-Based Sample of Diabetics in M'Bour Senegal

    ERIC Educational Resources Information Center

    BeLue, Rhonda; Ndiaye, Khadidiatou; NDao, Fatou; Ba, Fatou Niass Niang; Diaw, Mor

    2016-01-01

    Background: Sub-Saharan Africa (SSA) including Senegal is faced with a significant and increasing burden of type 2 diabetes. However, little information is available about diabetes management among Senegalese diabetics. Purpose: The current study aims to describe the level of glycemic control among a convenience sample of diabetics who receive…

  14. Radiation dose in the high background radiation area in Kerala, India.

    PubMed

    Christa, E P; Jojo, P J; Vaidyan, V K; Anilkumar, S; Eappen, K P

    2012-03-01

    A systematic radiological survey has been carried out in the region of high-background radiation area in Kollam district of Kerala to define the natural gamma-radiation levels. One hundred and forty seven soil samples from high-background radiation areas and five samples from normal background region were collected as per standard sampling procedures and were analysed for (238)U, (232)Th and (40)K by gamma-ray spectroscopy. External gamma dose rates at all sampling locations were also measured using a survey meter. The activities of (238)U, (232)Th and (40)K was found to vary from 17 to 3081 Bq kg(-1), 54 to 11976 Bq kg(-1) and BDL (67.4 Bq kg(-1)) to 216 Bq kg(-1), respectively, in the study area. Such heterogeneous distribution of radionuclides in the region may be attributed to the deposition phenomenon of beach sand soil in the region. Radium equivalent activities were found high in several locations. External gamma dose rates estimated from the levels of radionuclides in soil had a range from 49 to 9244 nGy h(-1). The result of gamma dose rate measured at the sampling sites using survey meter showed an excellent correlation with dose rates computed from the natural radionuclides estimated from the soil samples.

  15. Radio galaxies dominate the high-energy diffuse gamma-ray background

    DOE PAGES

    Hooper, Dan; Linden, Tim; Lopez, Alejandro

    2016-08-09

    It has been suggested that unresolved radio galaxies and radio quasars (sometimes referred to as misaligned active galactic nuclei) could be responsible for a significant fraction of the observed diffuse gamma-ray background. In this study, we use the latest data from the Fermi Gamma-Ray Space Telescope to characterize the gamma-ray emission from a sample of 51 radio galaxies. In addition to those sources that had previously been detected using Fermi data, we report here the first statistically significant detection of gamma-ray emission from the radio galaxies 3C 212, 3C 411, and B3 0309+411B. Combining this information with the radio fluxes,more » radio luminosity function, and redshift distribution of this source class, we find that radio galaxies dominate the diffuse gamma-ray background, generating 77.2(+25.4)(-9.4)% of this emission at energies above ~1 GeV . We discuss the implications of this result and point out that it provides support for scenarios in which IceCube's high-energy astrophysical neutrinos also originate from the same population of radio galaxies.« less

  16. General Aviation in Nebraska: Nebraska SATS Project Background Paper No. 1

    NASA Technical Reports Server (NTRS)

    Smith, Russell; Wachal, Jocelyn

    2000-01-01

    The Nebraska SATS project is a state-level component of NASA's Small Aircraft Transportation System (SATS). During the next several years the project will examine several different factors affecting SATS implementation in Nebraska. These include economic and taxation issues, public policy issues, airport planning processes, information dissemination strategies, and systemic change factors. This background paper profiles the general aviation system in Nebraska. It is written to provide information about the "context" within which SATS will be pursued. The primary focus is thus on describing and providing background information about the current situation. A secondary focus is on drawing general conclusions about the ability of the current system to incorporate the types of changes implied by SATS. First, some brief information on the U.S. aviation system is provided. The next two sections profile the current general aviation aircraft and pilot base. Nebraska's system of general aviation airports is then described. Within this section of the paper, information is provided on the different types of general aviation airports in Nebraska, airport activity levels and current infrastructure. The fourth major section of the background paper looks at Nebraska's local airport authorities. These special purpose local governments oversee the majority of the general aviation airports in the state. Among the items examined are total expenditures, capital expenditures and planning activities. Next, the paper provides background information on the Nebraska Department of Aeronautics (NDA) and recent Federal funding for general aviation in Nebraska. The final section presents summary conclusions.

  17. 16 CFR § 1404.2 - Background.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... INSULATION § 1404.2 Background. Based on available fire incident information, engineering analysis of the... fires can occur where cellulose insulation is improperly installed too close to the sides or over the top of recessed electrical light fixtures, or installed too close to the exhaust flues from heat...

  18. Contributions of Various Radiological Sources to Background in a Suburban Environment

    DOE PAGES

    Milvenan, Richard D.; Hayes, Robert B.

    2016-11-01

    This work is a brief overview and comparison of dose rates stemming from both indoor and outdoor natural background radiation and household objects within a suburban environment in North Carolina. Combined gamma and beta dose rates were taken from indoor objects that ranged from the potassium in fruit to the americium in smoke detectors. For outdoor measurements, various height and time data samples were collected to show fluctuations in dose rate due to temperature inversion and geometric attenuation. Although each sample tested proved to have a statistically significant increase over background using Students t-test, no sample proved to be moremore » than a minor increase in natural radiation dose. Furthermore, the relative contributions from natural radioactivity such as potassium in foods and common household items are shown to be easily distinguished from background using standard handheld instrumentation when applied in a systematic, methodological manner.« less

  19. Contributions of Various Radiological Sources to Background in a Suburban Environment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milvenan, Richard D.; Hayes, Robert B.

    This work is a brief overview and comparison of dose rates stemming from both indoor and outdoor natural background radiation and household objects within a suburban environment in North Carolina. Combined gamma and beta dose rates were taken from indoor objects that ranged from the potassium in fruit to the americium in smoke detectors. For outdoor measurements, various height and time data samples were collected to show fluctuations in dose rate due to temperature inversion and geometric attenuation. Although each sample tested proved to have a statistically significant increase over background using Students t-test, no sample proved to be moremore » than a minor increase in natural radiation dose. Furthermore, the relative contributions from natural radioactivity such as potassium in foods and common household items are shown to be easily distinguished from background using standard handheld instrumentation when applied in a systematic, methodological manner.« less

  20. Migrant Background and Weight Gain in Early Infancy: Results from the German Study Sample of the IDEFICS Study

    PubMed Central

    Reeske, Anna; Spallek, Jacob; Bammann, Karin; Eiben, Gabriele; De Henauw, Stefaan; Kourides, Yiannis; Nagy, Peter; Ahrens, Wolfgang

    2013-01-01

    Objective To examine variations in infant weight gain between children of parents with and without migrant background and to investigate how these differences are explained by pre- and perinatal factors. Methods We used data on birth weight and weight at six months from well-child check-up books that were collected from a population-based German sample of children in the IDEFICS study (n = 1,287). We calculated unadjusted and adjusted means for weight z-scores at birth and six months later. We applied linear regression for change in weight z-score and we calculated odds ratios and 95% confidence intervals (95% CI) for rapid weight gain by logistic regression, adjusted for biological, social and behavioural factors. Results Weight z-scores for migrants and Germans differed slightly at birth, but were markedly increased for Turkish and Eastern European infants at age six months. Turkish infants showed the highest change in weight z-score during the first 6 months (ß = 0.35; 95% CI 0.14–0.56) and an increased probability of rapid weight gain compared with German infants. Examination of the joint effect of migrant and socioeconomic status (SES) showed the greatest change in weight z-scores in Turkish infants from middle SES families (ß = 0.77; 95% CI 0.40–1.14) and infants of parents from Eastern European countries with high SES (ß = 0.72; 95% CI 0.13–1.32). Conclusions Our results support the hypothesis that migrant background is an independent risk factor for infant weight gain and suggest that the onset of health inequalities in overweight starts in early infancy. PMID:23593270

  1. Simple automatic strategy for background drift correction in chromatographic data analysis.

    PubMed

    Fu, Hai-Yan; Li, He-Dong; Yu, Yong-Jie; Wang, Bing; Lu, Peng; Cui, Hua-Peng; Liu, Ping-Ping; She, Yuan-Bin

    2016-06-03

    Chromatographic background drift correction, which influences peak detection and time shift alignment results, is a critical stage in chromatographic data analysis. In this study, an automatic background drift correction methodology was developed. Local minimum values in a chromatogram were initially detected and organized as a new baseline vector. Iterative optimization was then employed to recognize outliers, which belong to the chromatographic peaks, in this vector, and update the outliers in the baseline until convergence. The optimized baseline vector was finally expanded into the original chromatogram, and linear interpolation was employed to estimate background drift in the chromatogram. The principle underlying the proposed method was confirmed using a complex gas chromatographic dataset. Finally, the proposed approach was applied to eliminate background drift in liquid chromatography quadrupole time-of-flight samples used in the metabolic study of Escherichia coli samples. The proposed method was comparable with three classical techniques: morphological weighted penalized least squares, moving window minimum value strategy and background drift correction by orthogonal subspace projection. The proposed method allows almost automatic implementation of background drift correction, which is convenient for practical use. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. The Use of Criminal History Information in College Admissions Decisions

    ERIC Educational Resources Information Center

    Pierce, Matthew W.; Runyan, Carol W.; Bangdiwala, Shrikant I.

    2014-01-01

    To understand the potential public health and social justice implications of criminal background screening on college admissions, we examined postsecondary institutions' reasons for collecting or not collecting applicants' criminal justice information. We invited heads of admissions from 300 randomly sampled postsecondary institutions to complete…

  3. Field Sampling Plan for Closure of the Central Facilities Area Sewage Treatment Plant Lagoon 3 and Land Application Area

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis, Michael George

    This field sampling plan describes sampling of the soil/liner of Lagoon 3 at the Central Facilities Area Sewage Treatment Plant. The lagoon is to be closed, and samples obtained from the soil/liner will provide information to determine if Lagoon 3 and the land application area can be closed in a manner that renders it safe to human health and the environment. Samples collected under this field sampling plan will be compared to Idaho National Laboratory background soil concentrations. If the concentrations of constituents of concern exceed the background level, they will be compared to Comprehensive Environmental Response, Compensation, and Liabilitymore » Act preliminary remediation goals and Resource Conservation and Recovery Act levels. If the concentrations of constituents of concern are lower than the background levels, Resource Conservation and Recovery Act levels, or the preliminary remediation goals, then Lagoon 3 and the land application area will be closed. If the Resource Conservation and Recovery Act levels and/or the Comprehensive Environmental Response, Compensation, and Liability Act preliminary remediation goals are exceeded, additional sampling and action may be required.« less

  4. Enhancements to the MCNP6 background source

    DOE PAGES

    McMath, Garrett E.; McKinney, Gregg W.

    2015-10-19

    The particle transport code MCNP has been used to produce a background radiation data file on a worldwide grid that can easily be sampled as a source in the code. Location-dependent cosmic showers were modeled by Monte Carlo methods to produce the resulting neutron and photon background flux at 2054 locations around Earth. An improved galactic-cosmic-ray feature was used to model the source term as well as data from multiple sources to model the transport environment through atmosphere, soil, and seawater. A new elevation scaling feature was also added to the code to increase the accuracy of the cosmic neutronmore » background for user locations with off-grid elevations. Furthermore, benchmarking has shown the neutron integral flux values to be within experimental error.« less

  5. 40 CFR 91.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... that complete mixing of the engine exhaust and background air is assured prior to the sampling probe.... The background probe must draw a representative sample of the background air during each sampling mode...) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe, this system...

  6. 40 CFR 91.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... that complete mixing of the engine exhaust and background air is assured prior to the sampling probe.... The background probe must draw a representative sample of the background air during each sampling mode...) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe, this system...

  7. 40 CFR 91.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... that complete mixing of the engine exhaust and background air is assured prior to the sampling probe.... The background probe must draw a representative sample of the background air during each sampling mode...) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe, this system...

  8. 40 CFR 91.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... that complete mixing of the engine exhaust and background air is assured prior to the sampling probe.... The background probe must draw a representative sample of the background air during each sampling mode...) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe, this system...

  9. 40 CFR 91.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... that complete mixing of the engine exhaust and background air is assured prior to the sampling probe.... The background probe must draw a representative sample of the background air during each sampling mode...) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe, this system...

  10. Sample Collection Information Document for Chemical & Radiochemical Analytes – Companion to Selected Analytical Methods for Environmental Remediation and Recovery (SAM) 2012

    EPA Pesticide Factsheets

    Sample Collection Information Document is intended to provide sampling information to be used during site assessment, remediation and clearance activities following a chemical or radiological contamination incident.

  11. The Input and Process Batteries for MISOE [Management Information System for Occupational Education] Sample Data Systems.

    ERIC Educational Resources Information Center

    Weinberger, Elizabeth

    The document contains optical scannable forms for some of the instruments in the Input and Process Batteries, and guidelines for administration of the instruments in the Input Batteries of the Management Information System for Occupational Education (MISOE) Sample Data Systems. Input information describes the characteristics of the students at…

  12. Survey of background scattering from materials found in small-angle neutron scattering.

    PubMed

    Barker, J G; Mildner, D F R

    2015-08-01

    Measurements and calculations of beam attenuation and background scattering for common materials placed in a neutron beam are presented over the temperature range of 300-700 K. Time-of-flight (TOF) measurements have also been made, to determine the fraction of the background that is either inelastic or quasi-elastic scattering as measured with a 3 He detector. Other background sources considered include double Bragg diffraction from windows or samples, scattering from gases, and phonon scattering from solids. Background from the residual air in detector vacuum vessels and scattering from the 3 He detector dome are presented. The thickness dependence of the multiple scattering correction for forward scattering from water is calculated. Inelastic phonon background scattering at small angles for crystalline solids is both modeled and compared with measurements. Methods of maximizing the signal-to-noise ratio by material selection, choice of sample thickness and wavelength, removal of inelastic background by TOF or Be filters, and removal of spin-flip scattering with polarized beam analysis are discussed.

  13. Survey of background scattering from materials found in small-angle neutron scattering

    PubMed Central

    Barker, J. G.; Mildner, D. F. R.

    2015-01-01

    Measurements and calculations of beam attenuation and background scattering for common materials placed in a neutron beam are presented over the temperature range of 300–700 K. Time-of-flight (TOF) measurements have also been made, to determine the fraction of the background that is either inelastic or quasi-elastic scattering as measured with a 3He detector. Other background sources considered include double Bragg diffraction from windows or samples, scattering from gases, and phonon scattering from solids. Background from the residual air in detector vacuum vessels and scattering from the 3He detector dome are presented. The thickness dependence of the multiple scattering correction for forward scattering from water is calculated. Inelastic phonon background scattering at small angles for crystalline solids is both modeled and compared with measurements. Methods of maximizing the signal-to-noise ratio by material selection, choice of sample thickness and wavelength, removal of inelastic background by TOF or Be filters, and removal of spin-flip scattering with polarized beam analysis are discussed. PMID:26306088

  14. Calculating background levels for ecological risk parameters in toxic harbor sediment

    USGS Publications Warehouse

    Leadon, C.J.; McDonnell, T.R.; Lear, J.; Barclift, D.

    2007-01-01

    Establishing background levels for biological parameters is necessary in assessing the ecological risks from harbor sediment contaminated with toxic chemicals. For chemicals in sediment, the term contaminated is defined as having concentrations above background and significant human health or ecological risk levels. For biological parameters, a site could be considered contaminated if levels of the parameter are either more or less than the background level, depending on the specific parameter. Biological parameters can include tissue chemical concentrations in ecological receptors, bioassay responses, bioaccumulation levels, and benthic community metrics. Chemical parameters can include sediment concentrations of a variety of potentially toxic chemicals. Indirectly, contaminated harbor sediment can impact shellfish, fish, birds, and marine mammals, and human populations. This paper summarizes the methods used to define background levels for chemical and biological parameters from a survey of ecological risk investigations of marine harbor sediment at California Navy bases. Background levels for regional biological indices used to quantify ecological risks for benthic communities are also described. Generally, background stations are positioned in relatively clean areas exhibiting the same physical and general chemical characteristics as nearby areas with contaminated harbor sediment. The number of background stations and the number of sample replicates per background station depend on the statistical design of the sediment ecological risk investigation, developed through the data quality objective (DQO) process. Biological data from the background stations can be compared to data from a contaminated site by using minimum or maximum background levels or comparative statistics. In Navy ecological risk assessments (ERA's), calculated background levels and appropriate ecological risk screening criteria are used to identify sampling stations and sites with contaminated

  15. WIS Implementation Study Report. Volume 3. Background Information.

    DTIC Science & Technology

    1983-10-01

    similar representations so that a single schema interpreter can serve in either environment. Examples of schema intepreters exist in all databases...Unfortunately, programs expect ing ;L VSA M file caninot accept a similar, non-VSAM file instead. In practice, a tile written using any of tire 6 film ...Thomas Kaczmarek USC/Information Sciences Institute 4676 Admiralty Way Marina del Rey, CA 90292 14 September 1983 247 PAiIECDIG PAMI &~A -NOT FILM

  16. HPV and HPV vaccine information among a national sample of college and university websites.

    PubMed

    Fontenot, Holly B; Fantasia, Heidi Collins; Sutherland, Melissa A; Lee-St John, Terrence

    2016-04-01

    To describe the availability of human papillomavirus (HPV) and HPV vaccine information accessible to college students via official college and university websites. A review and analysis of HPV and HPV vaccination information abstracted from a national sample (n = 214) of college/university websites. Three abstractors systematically evaluated quality and quantity of vaccination, sexual health, and HPV disease information from health service webpages. The majority of colleges/universities had designated student health service webpages (n = 181). Of these, 86% provided information on vaccinations, but less than 50% mentioned HPV or the HPV vaccine specifically and only 32% provided any HPV educational information. Colleges/university webpages that provide sexual health and or general vaccination information had higher odds of providing information on HPV and HPV vaccination. Nurse practitioners who care for college-aged persons need to be cognizant of the many ways they can promote HPV vaccination. Providing accurate information about resources available at student health centers is a way to promote health on campus; the findings from this study indicate that HPV and HPV vaccine information may be lacking on many college/university websites. ©2015 American Association of Nurse Practitioners.

  17. Where and when should sensors move? Sampling using the expected value of information.

    PubMed

    de Bruin, Sytze; Ballari, Daniela; Bregt, Arnold K

    2012-11-26

    In case of an environmental accident, initially available data are often insufficient for properly managing the situation. In this paper, new sensor observations are iteratively added to an initial sample by maximising the global expected value of information of the points for decision making. This is equivalent to minimizing the aggregated expected misclassification costs over the study area. The method considers measurement error and different costs for class omissions and false class commissions. Constraints imposed by a mobile sensor web are accounted for using cost distances to decide which sensor should move to the next sample location. The method is demonstrated using synthetic examples of static and dynamic phenomena. This allowed computation of the true misclassification costs and comparison with other sampling approaches. The probability of local contamination levels being above a given critical threshold were computed by indicator kriging. In the case of multiple sensors being relocated simultaneously, a genetic algorithm was used to find sets of suitable new measurement locations. Otherwise, all grid nodes were searched exhaustively, which is computationally demanding. In terms of true misclassification costs, the method outperformed random sampling and sampling based on minimisation of the kriging variance.

  18. Where and When Should Sensors Move? Sampling Using the Expected Value of Information

    PubMed Central

    de Bruin, Sytze; Ballari, Daniela; Bregt, Arnold K.

    2012-01-01

    In case of an environmental accident, initially available data are often insufficient for properly managing the situation. In this paper, new sensor observations are iteratively added to an initial sample by maximising the global expected value of information of the points for decision making. This is equivalent to minimizing the aggregated expected misclassification costs over the study area. The method considers measurement error and different costs for class omissions and false class commissions. Constraints imposed by a mobile sensor web are accounted for using cost distances to decide which sensor should move to the next sample location. The method is demonstrated using synthetic examples of static and dynamic phenomena. This allowed computation of the true misclassification costs and comparison with other sampling approaches. The probability of local contamination levels being above a given critical threshold were computed by indicator kriging. In the case of multiple sensors being relocated simultaneously, a genetic algorithm was used to find sets of suitable new measurement locations. Otherwise, all grid nodes were searched exhaustively, which is computationally demanding. In terms of true misclassification costs, the method outperformed random sampling and sampling based on minimisation of the kriging variance. PMID:23443379

  19. Optimal Background Estimators in Single-Molecule FRET Microscopy.

    PubMed

    Preus, Søren; Hildebrandt, Lasse L; Birkedal, Victoria

    2016-09-20

    Single-molecule total internal reflection fluorescence (TIRF) microscopy constitutes an umbrella of powerful tools that facilitate direct observation of the biophysical properties, population heterogeneities, and interactions of single biomolecules without the need for ensemble synchronization. Due to the low signal/noise ratio in single-molecule TIRF microscopy experiments, it is important to determine the local background intensity, especially when the fluorescence intensity of the molecule is used quantitatively. Here we compare and evaluate the performance of different aperture-based background estimators used particularly in single-molecule Förster resonance energy transfer. We introduce the general concept of multiaperture signatures and use this technique to demonstrate how the choice of background can affect the measured fluorescence signal considerably. A new, to our knowledge, and simple background estimator is proposed, called the local statistical percentile (LSP). We show that the LSP background estimator performs as well as current background estimators at low molecular densities and significantly better in regions of high molecular densities. The LSP background estimator is thus suited for single-particle TIRF microscopy of dense biological samples in which the intensity itself is an observable of the technique. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  20. Low-background gamma-ray spectrometry for the international monitoring system

    DOE PAGES

    Greenwood, L. R.; Cantaloub, M. G.; Burnett, J. L.; ...

    2016-12-28

    PNNL has developed two low-background gamma-ray spectrometers in a new shallow underground laboratory, thereby significantly improving its ability to detect low levels of gamma-ray emitting fission or activation products in airborne particulate in samples from the IMS (International Monitoring System). Furthermore, the combination of cosmic veto panels, dry nitrogen gas to reduce radon and low background shielding results in a reduction of the background count rate by about a factor of 100 compared to detectors operating above ground at our laboratory.

  1. Beyond scene gist: Objects guide search more than scene background.

    PubMed

    Koehler, Kathryn; Eckstein, Miguel P

    2017-06-01

    Although the facilitation of visual search by contextual information is well established, there is little understanding of the independent contributions of different types of contextual cues in scenes. Here we manipulated 3 types of contextual information: object co-occurrence, multiple object configurations, and background category. We isolated the benefits of each contextual cue to target detectability, its impact on decision bias, confidence, and the guidance of eye movements. We find that object-based information guides eye movements and facilitates perceptual judgments more than scene background. The degree of guidance and facilitation of each contextual cue can be related to its inherent informativeness about the target spatial location as measured by human explicit judgments about likely target locations. Our results improve the understanding of the contributions of distinct contextual scene components to search and suggest that the brain's utilization of cues to guide eye movements is linked to the cue's informativeness about the target's location. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  2. Development of spatial scaling technique of forest health sample point information

    NASA Astrophysics Data System (ADS)

    Lee, J.; Ryu, J.; Choi, Y. Y.; Chung, H. I.; Kim, S. H.; Jeon, S. W.

    2017-12-01

    Most forest health assessments are limited to monitoring sampling sites. The monitoring of forest health in Britain in Britain was carried out mainly on five species (Norway spruce, Sitka spruce, Scots pine, Oak, Beech) Database construction using Oracle database program with density The Forest Health Assessment in GreatBay in the United States was conducted to identify the characteristics of the ecosystem populations of each area based on the evaluation of forest health by tree species, diameter at breast height, water pipe and density in summer and fall of 200. In the case of Korea, in the first evaluation report on forest health vitality, 1000 sample points were placed in the forests using a systematic method of arranging forests at 4Km × 4Km at regular intervals based on an sample point, and 29 items in four categories such as tree health, vegetation, soil, and atmosphere. As mentioned above, existing researches have been done through the monitoring of the survey sample points, and it is difficult to collect information to support customized policies for the regional survey sites. In the case of special forests such as urban forests and major forests, policy and management appropriate to the forest characteristics are needed. Therefore, it is necessary to expand the survey headquarters for diagnosis and evaluation of customized forest health. For this reason, we have constructed a method of spatial scale through the spatial interpolation according to the characteristics of each index of the main sample point table of 29 index in the four points of diagnosis and evaluation report of the first forest health vitality report, PCA statistical analysis and correlative analysis are conducted to construct the indicators with significance, and then weights are selected for each index, and evaluation of forest health is conducted through statistical grading.

  3. Interactive QR code beautification with full background image embedding

    NASA Astrophysics Data System (ADS)

    Lin, Lijian; Wu, Song; Liu, Sijiang; Jiang, Bo

    2017-06-01

    QR (Quick Response) code is a kind of two dimensional barcode that was first developed in automotive industry. Nowadays, QR code has been widely used in commercial applications like product promotion, mobile payment, product information management, etc. Traditional QR codes in accordance with the international standard are reliable and fast to decode, but are lack of aesthetic appearance to demonstrate visual information to customers. In this work, we present a novel interactive method to generate aesthetic QR code. By given information to be encoded and an image to be decorated as full QR code background, our method accepts interactive user's strokes as hints to remove undesired parts of QR code modules based on the support of QR code error correction mechanism and background color thresholds. Compared to previous approaches, our method follows the intention of the QR code designer, thus can achieve more user pleasant result, while keeping high machine readability.

  4. Implication of the first decision on visual information-sampling in the spatial frequency domain in pulmonary nodule recognition

    NASA Astrophysics Data System (ADS)

    Pietrzyk, Mariusz W.; Manning, David; Donovan, Tim; Dix, Alan

    2010-02-01

    Aim: To investigate the impact on visual sampling strategy and pulmonary nodule recognition of image-based properties of background locations in dwelled regions where the first overt decision was made. . Background: Recent studies in mammography show that the first overt decision (TP or FP) has an influence on further image reading including the correctness of the following decisions. Furthermore, the correlation between the spatial frequency properties of the local background following decision sites and the first decision correctness has been reported. Methods: Subjects with different radiological experience were eye tracked during detection of pulmonary nodules from PA chest radiographs. Number of outcomes and the overall quality of performance are analysed in terms of the cases where correct or incorrect decisions were made. JAFROC methodology is applied. The spatial frequency properties of selected local backgrounds related to a certain decisions were studied. ANOVA was used to compare the logarithmic values of energy carried by non redundant stationary wavelet packet coefficients. Results: A strong correlation has been found between the number of TP as a first decision and the JAFROC score (r = 0.74). The number of FP as a first decision was found negatively correlated with JAFROC (r = -0.75). Moreover, the differential spatial frequency profiles outcomes depend on the first choice correctness.

  5. Public School Accountability. Background Paper 95-14.

    ERIC Educational Resources Information Center

    Sturm, H. Pepper

    This paper describes the background of various accountability systems, discusses policy issues related to the use of educational accountability information, and offers a history of the school-accountability law in Nevada. The paper concludes that because policymakers continue to express concerns about uniform measurements and comparability, it is…

  6. Does Social Background Influence Political Science Grades?

    ERIC Educational Resources Information Center

    Tiruneh, Gizachew

    2013-01-01

    This paper tests a hypothesized linear relationship between social background and final grades in several political science courses that I taught at the University of Central Arkansas. I employ a cross-sectional research design and ordinary least square (OLS) estimators to test the foregoing hypothesis. Relying on a sample of up to 204…

  7. Background suppression of infrared small target image based on inter-frame registration

    NASA Astrophysics Data System (ADS)

    Ye, Xiubo; Xue, Bindang

    2018-04-01

    We propose a multi-frame background suppression method for remote infrared small target detection. Inter-frame information is necessary when the heavy background clutters make it difficult to distinguish real targets and false alarms. A registration procedure based on points matching in image patches is used to compensate the local deformation of background. Then the target can be separated by background subtraction. Experiments show our method serves as an effective preliminary of target detection.

  8. In-Home Respite Care Program Development. Background. Coordinator's Manual. Training Manual.

    ERIC Educational Resources Information Center

    Parham, J. D.; And Others

    This volume consists of a background discussion, coordinator's manual, and training manual dealing with developing programs for the in-home respite care (IHRC) of the developmentally disabled. Addressed in the background information unit are the nature of developmental disabilities; program variables, planning, and funding; and practical…

  9. Evaluation of background radiation dose contributions in the United Arab Emirates.

    PubMed

    Goddard, Braden; Bosc, Emmanuel; Al Hasani, Sarra; Lloyd, Cody

    2018-09-01

    The natural background radiation consists of three main components; cosmic, terrestrial, and skyshine. Although there are currently methods available to measure the total dose rate from background radiation, no established methods exist that allow for the measurement of each component the background radiation. This analysis consists of a unique methodology in which the dose rate contribution from each component of the natural background radiation is measured and calculated. This project evaluates the natural background dose rate in the Abu Dhabi City region from all three of these components using the developed methodology. Evaluating and understanding the different components of background radiation provides a baseline allowing for the detection, and possibly attribution, of elevated radiation levels. Measurements using a high-pressure ion chamber with different shielding configurations and two offshore measurements provided dose rate information that were attributed to the different components of the background radiation. Additional spectral information was obtained using an HPGe detector to verify and quantify the presence of terrestrial radionuclides. By evaluating the dose rates of the different shielding configurations the comic, terrestrial, and skyshine contribution in the Abu Dhabi City region were determined to be 33.0 ± 1.7, 15.7 ± 2.5, and 2.4 ± 2.1 nSv/h, respectively. Copyright © 2018. Published by Elsevier Ltd.

  10. Backgrounds, radiation damage, and spacecraft orbits

    NASA Astrophysics Data System (ADS)

    Grant, Catherine E.; Miller, Eric D.; Bautz, Mark W.

    2017-08-01

    The scientific utility of any space-based observatory can be limited by the on-orbit charged particle background and the radiation-induced damage. All existing and proposed missions have had to make choices about orbit selection, trading off the radiation environment against other factors. We present simulations from ESA’s SPace ENVironment Information System (SPENVIS) of the radiation environment for spacecraft in a variety of orbits, from Low Earth Orbit (LEO) at multiple inclinations to High Earth Orbit (HEO) to Earth-Sun L2 orbit. We summarize how different orbits change the charged particle background and the radiation damage to the instrument. We also discuss the limitations of SPENVIS simulations, particularly outside the Earth’s trapped radiation and point to new resources attempting to address those limitations.

  11. The role of digital sample information within the digital geoscience infrastructure: a pragmatic approach

    NASA Astrophysics Data System (ADS)

    Howe, Michael

    2014-05-01

    Much of the digital geological information on the composition, properties and dynamics of the subsurface is based ultimately on physical samples, many of which are archived to provide a basis for the information. Online metadata catalogues of these collections have now been available for many years. Many of these are institutional and tightly focussed, with UK examples including the British Geological Survey's (BGS) palaeontological samples database, PalaeoSaurus (http://www.bgs.ac.uk/palaeosaurus/), and mineralogical and petrological sample database, Britrocks (http://www.bgs.ac.uk/data/britrocks.html) . There are now a growing number of international sample metadata databases, including The Palaeobiology Database (http://paleobiodb.org/) and SESAR, the IGSN (International Geo Sample Number) database (http://www.geosamples.org/catalogsearch/ ). More recently the emphasis has moved beyond metadata (locality, identification, age, citations, etc) to digital imagery, with the intention of providing the user with at least enough information to determine whether viewing the sample would be worthwhile. Recent BGS examples include high resolution (e.g. 7216 x 5412 pixel) hydrocarbon well core images (http://www.bgs.ac.uk/data/offshoreWells/wells.cfc?method=searchWells) , high resolution rock thin section images (e.g. http://www.largeimages.bgs.ac.uk/iip/britrocks.html?id=290000/291739 ) and building stone images (http://geoscenic.bgs.ac.uk/asset-bank/action/browseItems?categoryId=1547&categoryTypeId=1) . This has been developed further with high resolution stereo images. The Jisc funded GB3D type fossils online project delivers these as red-cyan anaglyphs (http://www.3d-fossils.ac.uk/). More innovatively, the GB3D type fossils project has laser scanned several thousand type fossils and the resulting 3d-digital models are now being delivered through the online portal. Importantly, this project also represents collaboration between the BGS, Oxford and Cambridge Universities

  12. Preferences towards Sex Education and Information from an Ethnically Diverse Sample of Young People

    ERIC Educational Resources Information Center

    Coleman, L.; Testa, A.

    2007-01-01

    This paper reports sex education preferences from an ethnically diverse sample of 3007 15-18 year olds. Findings are presented on preferred topics, where and from whom young people would like to receive this information. Preferences were centred around learning more about sexual behaviour and sexually transmitted infections (STIs) in particular,…

  13. The Cosmic Infrared Background Experiment (CIBER): A Sounding Rocket Payload to Study the near Infrared Extragalactic Background Light

    NASA Astrophysics Data System (ADS)

    Zemcov, M.; Arai, T.; Battle, J.; Bock, J.; Cooray, A.; Hristov, V.; Keating, B.; Kim, M. G.; Lee, D. H.; Levenson, L. R.; Mason, P.; Matsumoto, T.; Matsuura, S.; Nam, U. W.; Renbarger, T.; Sullivan, I.; Suzuki, K.; Tsumura, K.; Wada, T.

    2013-08-01

    The Cosmic Infrared Background Experiment (CIBER) is a suite of four instruments designed to study the near infrared (IR) background light from above the Earth's atmosphere. The instrument package comprises two imaging telescopes designed to characterize spatial anisotropy in the extragalactic IR background caused by cosmological structure during the epoch of reionization, a low resolution spectrometer to measure the absolute spectrum of the extragalactic IR background, and a narrow band spectrometer optimized to measure the absolute brightness of the zodiacal light foreground. In this paper we describe the design and characterization of the CIBER payload. The detailed mechanical, cryogenic, and electrical design of the system are presented, including all system components common to the four instruments. We present the methods and equipment used to characterize the instruments before and after flight, and give a detailed description of CIBER's flight profile and configurations. CIBER is designed to be recoverable and has flown four times, with modifications to the payload having been informed by analysis of the first flight data. All four instruments performed to specifications during the subsequent flights, and the scientific data from these flights are currently being analyzed.

  14. THE COSMIC INFRARED BACKGROUND EXPERIMENT (CIBER): A SOUNDING ROCKET PAYLOAD TO STUDY THE NEAR INFRARED EXTRAGALACTIC BACKGROUND LIGHT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zemcov, M.; Bock, J.; Hristov, V.

    2013-08-15

    The Cosmic Infrared Background Experiment (CIBER) is a suite of four instruments designed to study the near infrared (IR) background light from above the Earth's atmosphere. The instrument package comprises two imaging telescopes designed to characterize spatial anisotropy in the extragalactic IR background caused by cosmological structure during the epoch of reionization, a low resolution spectrometer to measure the absolute spectrum of the extragalactic IR background, and a narrow band spectrometer optimized to measure the absolute brightness of the zodiacal light foreground. In this paper we describe the design and characterization of the CIBER payload. The detailed mechanical, cryogenic, andmore » electrical design of the system are presented, including all system components common to the four instruments. We present the methods and equipment used to characterize the instruments before and after flight, and give a detailed description of CIBER's flight profile and configurations. CIBER is designed to be recoverable and has flown four times, with modifications to the payload having been informed by analysis of the first flight data. All four instruments performed to specifications during the subsequent flights, and the scientific data from these flights are currently being analyzed.« less

  15. Surface alpha backgrounds from plate-out of radon progeny

    NASA Astrophysics Data System (ADS)

    Perumpilly, Gopakumar; Guiseppe, Vincente

    2012-03-01

    Low-background detectors operating underground aim for unprecedented low levels of radioactive backgrounds. Although the radioactive decays of airborne radon (particularly Rn-222) and its subsequent daughters present in an experiment are potential backgrounds, more troublesome is the deposition of radon daughters on detector materials. Exposure to radon at any stage of assembly of an experiment can result in surface contamination by daughters supported by the long half life (22 y) of Pb-210 on sensitive locations of a detector. We have developed a model of the radon progeny implantation using Geant4 simulations based on the low energy nuclear recoil process. We explore the alpha decays from implanted progeny on a Ge crystal as potential backgrounds for a neutrinoless double-beta decay experiment. Results of the simulations validated with alpha spectrum measurement of plate-out samples will be presented.

  16. Egypt: Background and U.S. Relations

    DTIC Science & Technology

    2009-05-12

    contributions from Germany , Japan, and Switzerland. For more information on the MFO, see http://www.mfo.org/Default.asp?bhcp=1. Egypt: Background and...2008 Report, Egypt’s pace of business reforms and deregulation between 2006 and 2007 ranked first worldwide. In recent years, the state has...reinvigorated its privatization program by divesting shares in the state-dominated banking and insurance sectors. Additionally, the government removed import

  17. Fast Bayesian experimental design: Laplace-based importance sampling for the expected information gain

    NASA Astrophysics Data System (ADS)

    Beck, Joakim; Dia, Ben Mansour; Espath, Luis F. R.; Long, Quan; Tempone, Raúl

    2018-06-01

    In calculating expected information gain in optimal Bayesian experimental design, the computation of the inner loop in the classical double-loop Monte Carlo requires a large number of samples and suffers from underflow if the number of samples is small. These drawbacks can be avoided by using an importance sampling approach. We present a computationally efficient method for optimal Bayesian experimental design that introduces importance sampling based on the Laplace method to the inner loop. We derive the optimal values for the method parameters in which the average computational cost is minimized according to the desired error tolerance. We use three numerical examples to demonstrate the computational efficiency of our method compared with the classical double-loop Monte Carlo, and a more recent single-loop Monte Carlo method that uses the Laplace method as an approximation of the return value of the inner loop. The first example is a scalar problem that is linear in the uncertain parameter. The second example is a nonlinear scalar problem. The third example deals with the optimal sensor placement for an electrical impedance tomography experiment to recover the fiber orientation in laminate composites.

  18. Understandability of Patient Information Booklets for Patients with Cancer.

    PubMed

    Keinki, Christian; Zowalla, Richard; Wiesner, Martin; Koester, Marie Jolin; Huebner, Jutta

    2018-06-01

    The improvement of health literacy in general and the information of individual patient is a major concern of the German national cancer plan and similar initiatives in other western countries. The aim of our study was to assess the readability and understandability of information booklets for cancer patients available at German Web sites. A support vector machine (SVM) was used to discriminate between laymen- and expert-centric patient information booklets about nine most common tumor types. All booklets had to be available for free at the Internet. A total of 52 different patient booklets were downloaded and assessed. Overall, the assessment of all booklets showed that an understandability level L of 4.6 and therefore increased medical background knowledge is required to understand a random text selected from the sample. The assessed information booklets on cancer show very limited suitability for laymen. We were able to demonstrate that a medical background is necessary to understand the examined booklets. The current study highlights the need to create information material adjusted to the needs of laymen. Assessing understandability before publication, especially for laymen with low health literacy, could ensure the suitability and thus quality of the information material.

  19. From Cleanup to Stewardship. A companion report to Accelerating Cleanup: Paths to Closure and background information to support the scoping process required for the 1998 PEIS Settlement Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    1999-10-01

    Long-term stewardship is expected to be needed at more than 100 DOE sites after DOE's Environmental Management program completes disposal, stabilization, and restoration operations to address waste and contamination resulting from nuclear research and nuclear weapons production conducted over the past 50 years. From Cleanup to stewardship provides background information on the Department of Energy (DOE) long-term stewardship obligations and activities. This document begins to examine the transition from cleanup to long-term stewardship, and it fulfills the Secretary's commitment to the President in the 1999 Performance Agreement to provide a companion report to the Department's Accelerating Cleanup: Paths to Closuremore » report. It also provides background information to support the scoping process required for a study on long-term stewardship required by a 1998 Settlement Agreement.« less

  20. Optimal cross-sectional sampling for river modelling with bridges: An information theory-based method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ridolfi, E.; Napolitano, F., E-mail: francesco.napolitano@uniroma1.it; Alfonso, L.

    2016-06-08

    The description of river topography has a crucial role in accurate one-dimensional (1D) hydraulic modelling. Specifically, cross-sectional data define the riverbed elevation, the flood-prone area, and thus, the hydraulic behavior of the river. Here, the problem of the optimal cross-sectional spacing is solved through an information theory-based concept. The optimal subset of locations is the one with the maximum information content and the minimum amount of redundancy. The original contribution is the introduction of a methodology to sample river cross sections in the presence of bridges. The approach is tested on the Grosseto River (IT) and is compared to existingmore » guidelines. The results show that the information theory-based approach can support traditional methods to estimate rivers’ cross-sectional spacing.« less

  1. Low background screening capability in the UK

    NASA Astrophysics Data System (ADS)

    Ghag, Chamkaur

    2015-08-01

    Low background rare event searches in underground laboratories seeking observation of direct dark matter interactions or neutrino-less double beta decay have the potential to profoundly advance our understanding of the physical universe. Successful results from these experiments depend critically on construction from extremely radiologically clean materials and accurate knowledge of subsequent low levels of expected background. The experiments must conduct comprehensive screening campaigns to reduce radioactivity from detector components, and these measurements also inform detailed characterisation and quantification of background sources and their impact, necessary to assign statistical significance to any potential discovery. To provide requisite sensitivity for material screening and characterisation in the UK to support our rare event search activities, we have re-developed our infrastructure to add ultra-low background capability across a range of complementary techniques that collectively allow complete radioactivity measurements. Ultra-low background HPGe and BEGe detectors have been installed at the Boulby Underground Laboratory, itself undergoing substantial facility re-furbishment, to provide high sensitivity gamma spectroscopy in particular for measuring the uranium and thorium decay series products. Dedicated low-activity mass spectrometry instrumentation has been developed at UCL for part per trillion level contaminant identification to complement underground screening with direct U and Th measurements, and meet throughput demands. Finally, radon emanation screening at UCL measures radon background inaccessible to gamma or mass spectrometry techniques. With this new capability the UK is delivering half of the radioactivity screening for the LZ dark matter search experiment.

  2. Background factors related to and/or influencing occupation in mentally disordered offenders.

    PubMed

    Lindstedt, Helena; Ivarsson, Ann-Britt; Söderlund, Anne

    2006-09-01

    Knowledge of background and occupational related factors of mentally disordered offenders are missing. It is essential to understand these issues when planning discharge from forensic psychiatric hospital care to enable community dwelling. One aim was to investigate mentally disordered offenders' background factors, confidence in and how they value occupations. Another aim was to investigate MDOs background factors' in relation to and the influences on Occupational Performance and Social Participation. Data was collected with an explorative, correlative design after informed consent, from 74 mentally disordered offenders (mean age 34,2) cared for in forensic psychiatric hospitals. Assessments were Allen Cognitive Level Screen, Capability to Perform Daily Occupations, Interview Schedule of Social Interaction, Manchester Short Assessment of Quality of Life, Self-efficacy Scale and Importance scale. Eight background factors were assembled from the individual forensic psychiatric investigation. Most of the investigated background factors relate to and half of them influence occupational performance, particular the cognitive aspect of occupational performance. The influences on occupation originate from adulthood, such as suffering from schizophrenia, psycho/social problems, and having performed violent crimes. These findings indicate that staff in forensic hospital care should initiate rehabilitation with knowledge about MDOs' complex daily occupations. For avoiding information bias, information gathering preceding treatment planning should be performed in collaboration between caring staff and mentally disordered offenders.

  3. 76 FR 67182 - Agency Information Collection Activities; Proposed Collection; Comment Request; Background Checks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... Employees (Renewal) and Drug Testing for Contract Employees (Renewal) AGENCY: Environmental Protection...: EPA-HQ-OARM-2-11-0804, Drug Testing for Contractor Employees. Hand Delivery: EPA Docket Center... provide qualified personnel that meet the background check and drug testing requirements developed by EPA...

  4. Perfluorocarbon background concentrations in Europe

    NASA Astrophysics Data System (ADS)

    Straume, Anne Grete; Dietz, Russel N.; Koffı̀, Ernest N.'dri; Nodop, Katrin

    Five studies of the background level of several perfluorocarbon compounds in Europe are here presented together with measurements from the European Tracer Experiment (ETEX). The tracers used during the two ETEX tracer releases were the perfluorocarbons (PFCs); perfluoromethylcyclohexane (C 7F 14, PMCH) and perfluoromethylcyclopentane (C 6F 12, PMCP). Their background concentrations were detected by using both passive and active sampling techniques, to define the spatial and temporal variation of the PFCs over Europe. Also the background variations of four isomers of the PFC compound perfluorodimethylcyclohexane (C 8F 16, PDCH) were studied. The results were compared to other PFC tracer studies in the U.S.A. and Europe. The mean and median values of the measured PFCs were found to vary slightly and randomly in space and time. They were found to be higher and to have a larger standard deviation than the measurements from the American studies. The background concentrations were still found to be low and stable enough for PFCs to be highly suitable for use in tracer studies. The following concentrations were found: PMCP; 4.6±0.3 fl ℓ -1, PMCH: 4.6±0.8 fl ℓ -1, ocPDCH: 0.96±0.33 fl ℓ -1, mtPDCH: 9.3±0.8 fl ℓ -1, mcPDCH: 8.8±0.8 fl ℓ -1, ptPDCH: 6.1±0.8 fl ℓ -1. A study of the correlation between the measured PFC compounds showed a significant correlation between most of the compounds, which indicate that there are no major PFC sources in Europe.

  5. Quantitative autistic trait measurements index background genetic risk for ASD in Hispanic families.

    PubMed

    Page, Joshua; Constantino, John Nicholas; Zambrana, Katherine; Martin, Eden; Tunc, Ilker; Zhang, Yi; Abbacchi, Anna; Messinger, Daniel

    2016-01-01

    Recent studies have indicated that quantitative autistic traits (QATs) of parents reflect inherited liabilities that may index background genetic risk for clinical autism spectrum disorder (ASD) in their offspring. Moreover, preferential mating for QATs has been observed as a potential factor in concentrating autistic liabilities in some families across generations. Heretofore, intergenerational studies of QATs have focused almost exclusively on Caucasian populations-the present study explored these phenomena in a well-characterized Hispanic population. The present study examined QAT scores in siblings and parents of 83 Hispanic probands meeting research diagnostic criteria for ASD, and 64 non-ASD controls, using the Social Responsiveness Scale-2 (SRS-2). Ancestry of the probands was characterized by genotype, using information from 541,929 single nucleotide polymorphic markers. In families of Hispanic children with an ASD diagnosis, the pattern of quantitative trait correlations observed between ASD-affected children and their first-degree relatives (ICCs on the order of 0.20), between unaffected first-degree relatives in ASD-affected families (sibling/mother ICC = 0.36; sibling/father ICC = 0.53), and between spouses (mother/father ICC = 0.48) were in keeping with the influence of transmitted background genetic risk and strong preferential mating for variation in quantitative autistic trait burden. Results from analysis of ancestry-informative genetic markers among probands in this sample were consistent with that from other Hispanic populations. Quantitative autistic traits represent measurable indices of inherited liability to ASD in Hispanic families. The accumulation of autistic traits occurs within generations, between spouses, and across generations, among Hispanic families affected by ASD. The occurrence of preferential mating for QATs-the magnitude of which may vary across cultures-constitutes a mechanism by which background genetic liability

  6. Background Materials for Chairman's Workshop. 5th Edition.

    ERIC Educational Resources Information Center

    Kimble, Gregory A.

    Information for newly appointed heads of graduate departments of psychology is presented as background material for the 1974 Chairman's Workshop. Topics include the following: the budgetary situation, pressures for increased teaching loads, effects upon recruiting faculty, faculty morale, graduate and undergraduate student morale, the intellectual…

  7. Identification of Fluency and Word-Finding Difficulty in Samples of Children with Diverse Language Backgrounds

    ERIC Educational Resources Information Center

    Howell, Peter; Tang, Kevin; Tuomainen, Outi; Chan, Sin Kan; Beltran, Kirsten; Mirawdeli, Avin; Harris, John

    2017-01-01

    Background: Stuttering and word-finding difficulty (WFD) are two types of communication difficulty that occur frequently in children who learn English as an additional language (EAL), as well as those who only speak English. The two disorders require different, specific forms of intervention. Prior research has described the symptoms of each type…

  8. 40 CFR 90.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... sampling probe. (2) Exhaust flow metering system. A dilute exhaust flow metering system must be used to... exhaust. The background probe must draw a representative sample of the background air during each sampling... (bag) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe...

  9. 40 CFR 90.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... sampling probe. (2) Exhaust flow metering system. A dilute exhaust flow metering system must be used to... exhaust. The background probe must draw a representative sample of the background air during each sampling... (bag) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe...

  10. 40 CFR 90.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... sampling probe. (2) Exhaust flow metering system. A dilute exhaust flow metering system must be used to... exhaust. The background probe must draw a representative sample of the background air during each sampling... (bag) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe...

  11. 40 CFR 90.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... sampling probe. (2) Exhaust flow metering system. A dilute exhaust flow metering system must be used to... exhaust. The background probe must draw a representative sample of the background air during each sampling... (bag) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe...

  12. 40 CFR 90.420 - CVS concept of exhaust gas sampling system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sampling probe. (2) Exhaust flow metering system. A dilute exhaust flow metering system must be used to... exhaust. The background probe must draw a representative sample of the background air during each sampling... (bag) sampling system. If a critical flow venturi (CFV) is used on the dilute exhaust sample probe...

  13. User guide for luminescence sampling in archaeological and geological contexts

    USGS Publications Warehouse

    Nelson, Michelle S.; Gray, Harrison J.; Johnson, Jack A.; Rittenour, Tammy M.; Feathers, James K.; Mahan, Shannon

    2015-01-01

    Luminescence dating provides a direct age estimate of the time of last exposure of quartz or feldspar minerals to light or heat and has been successfully applied to deposits, rock surfaces, and fired materials in a number of archaeological and geological settings. Sampling strategies are diverse and can be customized depending on local circumstances, although all sediment samples need to include a light-safe sample and material for dose-rate determination. The accuracy and precision of luminescence dating results are directly related to the type and quality of the material sampled and sample collection methods in the field. Selection of target material for dating should include considerations of adequacy of resetting of the luminescence signal (optical and thermal bleaching), the ability to characterize the radioactive environment surrounding the sample (dose rate), and the lack of evidence for post-depositional mixing (bioturbation in soils and sediment). Sample strategies for collection of samples from sedimentary settings and fired materials are discussed. This paper should be used as a guide for luminescence sampling and is meant to provide essential background information on how to properly collect samples and on the types of materials suitable for luminescence dating.

  14. Development of a low background liquid scintillation counter for a shallow underground laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Erchinger, Jennifer L.; Aalseth, Craig E.; Bernacki, Bruce E.

    2015-08-20

    Pacific Northwest National Laboratory has recently opened a shallow underground laboratory intended for measurement of lowconcentration levels of radioactive isotopes in samples collected from the environment. The development of a low-background liquid scintillation counter is currently underway to further augment the measurement capabilities within this underground laboratory. Liquid scintillation counting is especially useful for measuring charged particle (e.g., B, a) emitting isotopes with no (orvery weak) gamma-ray yields. The combination of high-efficiency detection of charged particle emission in a liquid scintillation cocktail coupled with the low-background environment of an appropriately-designed shield located in a clean underground laboratory provides the opportunitymore » for increased-sensitivity measurements of a range of isotopes. To take advantage of the 35-meter water-equivalent overburden of the underground laboratory, a series of simulations have evaluated the instrumental shield design requirements to assess the possible background rate achievable. This report presents the design and background evaluation for a shallow underground, low background liquid scintillation counter design for sample measurements.« less

  15. Detecting the Stochastic Gravitational-Wave Background

    NASA Astrophysics Data System (ADS)

    Colacino, Carlo Nicola

    2017-12-01

    The stochastic gravitational-wave background (SGWB) is by far the most difficult source of gravitational radiation detect. At the same time, it is the most interesting and intriguing one. This book describes the initial detection of the SGWB and describes the underlying mathematics behind one of the most amazing discoveries of the 21st century. On the experimental side it would mean that interferometric gravitational wave detectors work even better than expected. On the observational side, such a detection could give us information about the very early Universe, information that could not be obtained otherwise. Even negative results and improved upper bounds could put constraints on many cosmological and particle physics models.

  16. [Self-directed learning and academic background of 2010 to 2014 cohorts of medical students].

    PubMed

    Pérez-Villalobos, Cristhian E; Fasce-Henry, Eduardo A; Ortega-Bastidas, Javiera A; Ortiz-Moreira, Liliana E; Bastías-Vega, Nancy; Bustamante-Durán, Carolina E; Ibáñez-Gracia, Pilar; Márquez-Urrizola, Carolina G; Delgado-Rivera, Macarena; Glaría-López, Rocío

    2017-07-01

    The widespread growth of higher education is increasing the heterogeneity of university students in terms of socioeconomic characteristics, academic story and cultural background. Medical schools are not an exception of this phenomenon. To compare the academic background and self-directed learning behavior of students who entered to a public medial school between 2010 and 2014. A non-probabilistic sample of 527 medical students aged between 17 and 29 years (60% men), was studied. Their academic information was collected from the University data base; they answered the Self-directed learning readiness scale of Fisher. Students from the 2014 cohort had higher high school grades than their counterparts. The scores in mathematics of the Scholarship Aptitude Test (SAT) were higher in the cohorts of 2010 and 2011. Those of the sciences test were superior in the 2013 cohort. The 2014 cohort had the lower general score of self-directed learning behaviors. The lower SAT and self-directed learning scores of the students entering medical school in 2014, indicate the progressive increase in the heterogeneity of Medical students.

  17. Time and expected value of sample information wait for no patient.

    PubMed

    Eckermann, Simon; Willan, Andrew R

    2008-01-01

    The expected value of sample information (EVSI) from prospective trials has previously been modeled as the product of EVSI per patient, and the number of patients across the relevant time horizon less those "used up" in trials. However, this implicitly assumes the eligible patient population to which information from a trial can be applied across a time horizon are independent of time for trial accrual, follow-up and analysis. This article demonstrates that in calculating the EVSI of a trial, the number of patients who benefit from trial information should be reduced by those treated outside as well as within the trial over the time until trial evidence is updated, including time for accrual, follow-up and analysis. Accounting for time is shown to reduce the eligible patient population: 1) independent of the size of trial in allowing for time of follow-up and analysis, and 2) dependent on the size of trial for time of accrual, where the patient accrual rate is less than incidence. Consequently, the EVSI and expected net gain (ENG) at any given trial size are shown to be lower when accounting for time, with lower ENG reinforced in the case of trials undertaken while delaying decisions by additional opportunity costs of time. Appropriately accounting for time reduces the EVSI of trial design and increase opportunity costs of trials undertaken with delay, leading to lower likelihood of trialing being optimal and smaller trial designs where optimal.

  18. Diffuse neutrino supernova background as a cosmological test

    NASA Astrophysics Data System (ADS)

    Barranco, J.; Bernal, A.; Delepine, D.

    2018-05-01

    The future detection and measurement of the diffuse neutrino supernova background will provide us with information about supernova neutrino emission and the cosmic core-collapse supernova rate. Little has been said about the information that this measurement could give us about the expansion history of the Universe. The purpose of this article is to study the change of the predicted diffuse supernova neutrino background as a function of the cosmological model. In particular, we study three different models: the Λ–Cold Dark Matter model, the Logotropic universe and a bulk viscous matter-dominated universe. By fitting the free parameters of each model with the supernova Ia probe, we calculate the predicted number of events in these three models. We found that the spectra and number of events for the Λ–Cold dark matter model and the Logotropic model are almost indistinguishable, while a bulk viscous matter-dominated cosmological model predicts more events.

  19. Adult Literacy Information and Evaluation System (ALIES): Background, Status and Future Directions.

    ERIC Educational Resources Information Center

    Cook, Jacqueline; And Others

    This document describes the Adult Literacy Information and Evaluation System (ALIES), which is the management information system for New York City's citywide adult education program expansion effort begun in 1984. Chapter 1 describes the organization's creation in order to provide timely and reliable information to funders about the effects of the…

  20. Information visualization courses for students with a computer science background.

    PubMed

    Kerren, Andreas

    2013-01-01

    Linnaeus University offers two master's courses in information visualization for computer science students with programming experience. This article briefly describes the syllabi, exercises, and practices developed for these courses.

  1. Attitudes towards information system security among physicians in Croatia.

    PubMed

    Markota, M; Kern, J; Svab, I

    2001-07-01

    To examine attitudes about information system security among Croatian physicians a cross-sectional study was performed on a representative sample of 800 Croatian physicians. An anonymous questionnaire comprising 21 questions was distributed and statistical analysis was performed using a chi-square test. A 76.2% response rate was obtained. The majority of respondents (85.8%) believe that information system security is a new area in their work. In general, physicians are not informed about European directives, conventions, recommendations, etc. Only a small number of physicians use personal computers at work (29%). Those physicians who have a personal computer use it mainly for administrative reasons. Most healthcare institutions (89%) do not have a security manual and the area of information system security is left to individual interest and initiative. Only 25% of physicians who have a personal computer use any type of password. A high percentage of physicians (22%) has never thought about the problem of personal data being used by organizations (e.g. police, banks) without legal background; a small, but still significant percentage of physicians (5.6%) has even agreed with such use. Results indicate that for the vast majority of physicians, information system security is a new area in their daily work, one which is left to individual interest and initiative. They are not familiar with the ethical, technical and legal backgrounds which have been defined for that area within the Council of Europe and the European Union. New aspects: This is the first study performed in Central and Eastern Europe dealing with information system security, performed on a representative nationwide sample of all the physicians.

  2. Analysis of potential influence factors on background urinary benzene concentration among a non-smoking, non-occupationally exposed general population sample.

    PubMed

    Campagna, Marcello; Satta, Giannina; Campo, Laura; Flore, Valeria; Ibba, Antonio; Meloni, Michele; Tocco, Maria Giuseppina; Avataneo, Giuseppe; Flore, Costantino; Fustinoni, Silvia; Cocco, Pierluigi

    2014-01-01

    Analytical difficulties and lack of a biological exposure index and reference values have prevented using unmetabolized urinary benzene (UB) excretion as a biomarker of low-level environmental exposure. To explore what environmental factors beyond active smoking may contribute to environmental exposure to benzene, we monitored UB excretion in a non-smoking, non-occupationally exposed sample of the general population. Two spot urine samples were obtained from 86 non-smoking, non-occupationally exposed subjects, selected among a random sample of the general population of the metropolitan area of Cagliari (Sardinia, Italy), at 8:00 a.m. (UBm) and 8:00 p.m. (UBe). UB was measured by headspace solid-phase microextraction (HS-SPME) followed by gas chromatography-mass spectrometry analysis. Questionnaire information on personal and environmental exposures during the sampling day was gathered with personal interviews. Multivariate analysis of variance and multiple regression model were applied to investigate the role of such variables on the level of UB. The ninety-fifth percentile of UBe in this population was 311.5 ng/L, which is tentatively proposed as the UB guidance value for unexposed populations. UBm and urban residence were the only predictors of a significant increase in UBe excretion. Self-reported residential vehicular traffic will not account for the excess median value among urban residents; commuting time among urban residents showed a suggestive nonsignificant linear correlation with UBe, but the small sample size prevented reliable inference to be drawn. Age, environmental tobacco smoking, employment status and body mass index did not affect UB excretion. Our findings support the use of unmetabolized UB as a specific and sensitive biomarker of low-level environmental exposure to benzene.

  3. Routine conventional karyotyping of lymphoma staging bone marrow samples does not contribute clinically relevant information.

    PubMed

    Nardi, Valentina; Pulluqi, Olja; Abramson, Jeremy S; Dal Cin, Paola; Hasserjian, Robert P

    2015-06-01

    Bone marrow (BM) evaluation is an important part of lymphoma staging, which guides patient management. Although positive staging marrow is defined as morphologically identifiable disease, such samples often also include flow cytometric analysis and conventional karyotyping. Cytogenetic analysis is a labor-intensive and costly procedure and its utility in this setting is uncertain. We retrospectively reviewed pathological reports of 526 staging marrow specimens in which conventional karyotyping had been performed. All samples originated from a single institution from patients with previously untreated Hodgkin and non-Hodgkin lymphomas presenting in an extramedullary site. Cytogenetic analysis revealed clonal abnormalities in only eight marrow samples (1.5%), all of which were positive for lymphoma by morphologic evaluation. Flow cytometry showed a small clonal lymphoid population in three of the 443 morphologically negative marrow samples (0.7%). Conventional karyotyping is rarely positive in lymphoma staging marrow samples and, in our cohort, the BM karyotype did not contribute clinically relevant information in the vast majority of cases. Our findings suggest that karyotyping should not be performed routinely on BM samples taken to stage previously diagnosed extramedullary lymphomas unless there is pathological evidence of BM involvement by lymphoma. © 2015 Wiley Periodicals, Inc.

  4. Quantifications of dendrochronological information from contrasting microdensitometric measuring circumstances of experimental wood samples.

    PubMed

    Helama, S; Bégin, Y; Vartiainen, M; Peltola, H; Kolström, T; Meriläinen, J

    2012-06-01

    We analyzed how the pretreatment method of Scots pine (Pinus sylvestris L.) wood specimens together with X-ray methodology applied for density analyses affect resulting tree-ring data and derived proxy-based climate information. We also evaluated whether these results from two contrasting laboratory circumstances could be homogenized by applying dendroclimatic statistical methods. For this study, we measured a pair of X-ray based microdensitometry datasets using double samples of subfossil and recent wood specimens. Dendrochronological information of earlywood and latewood series was examined to determine for alterations in the resulting data. We found that the level of overall density, its trend over cambial ages and the growth amplitude altered due to the sample pretreatment/density measuring exercise, which means that comparisons of heterogeneous datasets should be, in general, regarded cautiously. Dendrochronological standardization did, however, even out several potentially biasing influences from the differing overall densities and their trends. The two latewood (maximum) density chronologies yielded paleoclimatic reconstructions which both calibrated and verified satisfactorily with the instrumental warm-season (March-September) mean temperatures. The transfer functions were found to further equalize the differences between the two proxy records. We recommend (if no strictly homogenous data are available) reconciling similar data assemblages through transfer functions with multiple independent variables. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Conceptual Model of Clinical Governance Information System for Statistical Indicators by Using UML in Two Sample Hospitals.

    PubMed

    Jeddi, Fatemeh Rangraz; Farzandipoor, Mehrdad; Arabfard, Masoud; Hosseini, Azam Haj Mohammad

    2014-04-01

    The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital's clinical governance was required to create a database. Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems.

  6. Conceptual Model of Clinical Governance Information System for Statistical Indicators by Using UML in Two Sample Hospitals.

    PubMed

    Jeddi, Fatemeh Rangraz; Farzandipoor, Mehrdad; Arabfard, Masoud; Hosseini, Azam Haj Mohammad

    2016-04-01

    The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital's clinical governance was required to create a database. Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems.

  7. Characterizing spatial structure of sediment E. coli populations to inform sampling design.

    PubMed

    Piorkowski, Gregory S; Jamieson, Rob C; Hansen, Lisbeth Truelstrup; Bezanson, Greg S; Yost, Chris K

    2014-01-01

    Escherichia coli can persist in streambed sediments and influence water quality monitoring programs through their resuspension into overlying waters. This study examined the spatial patterns in E. coli concentration and population structure within streambed morphological features during baseflow and following stormflow to inform sampling strategies for representative characterization of E. coli populations within a stream reach. E. coli concentrations in bed sediments were significantly different (p = 0.002) among monitoring sites during baseflow, and significant interactive effects (p = 0.002) occurred among monitoring sites and morphological features following stormflow. Least absolute shrinkage and selection operator (LASSO) regression revealed that water velocity and effective particle size (D 10) explained E. coli concentration during baseflow, whereas sediment organic carbon, water velocity and median particle diameter (D 50) were important explanatory variables following stormflow. Principle Coordinate Analysis illustrated the site-scale differences in sediment E. coli populations between disconnected stream segments. Also, E. coli populations were similar among depositional features within a reach, but differed in relation to high velocity features (e.g., riffles). Canonical correspondence analysis resolved that E. coli population structure was primarily explained by spatial (26.9–31.7 %) over environmental variables (9.2–13.1 %). Spatial autocorrelation existed among monitoring sites and morphological features for both sampling events, and gradients in mean particle diameter and water velocity influenced E. coli population structure for the baseflow and stormflow sampling events, respectively. Representative characterization of streambed E. coli requires sampling of depositional and high velocity environments to accommodate strain selectivity among these features owing to sediment and water velocity heterogeneity.

  8. [Maintenance treatment in opioid-dependent patients with migration background].

    PubMed

    Bald, L K; Schouler-Ocak, M; Penka, S; Schoofs, N; Häbel, T; Bermpohl, F; Gutwinski, S

    2016-05-01

    No regional analyses regarding opioid-dependent patients in maintenance treatment with a migration background have so far been performed in German-speaking countries. This study examined patients with and without a migration background regarding socioeconomic parameters, characteristics of dependency and attitude towards opiate maintenance treatment (OMT). From May to October 2011 patients in OMT from all of the 20 psychiatry clinics and 110 physician practices in Berlin with a licence to provide OMT were included in this analysis. Out of the 986 participating patients, 956 gave information on migration background and of these, 204 (21.3 %) originated from a country other than Germany. Compared to patients without a migration background, their participation in a maintenance program was significantly shorter and they more often expressed a desire to end OMT and wanted a limited duration of OMT. The differences regarding duration of OMT and the wish to end OMT can reflect a stronger desire for abstinence and a different attitude towards maintenance treatment of patients with a migration background.

  9. Background Noise Reduction Using Adaptive Noise Cancellation Determined by the Cross-Correlation

    NASA Technical Reports Server (NTRS)

    Spalt, Taylor B.; Brooks, Thomas F.; Fuller, Christopher R.

    2012-01-01

    Background noise due to flow in wind tunnels contaminates desired data by decreasing the Signal-to-Noise Ratio. The use of Adaptive Noise Cancellation to remove background noise at measurement microphones is compromised when the reference sensor measures both background and desired noise. The technique proposed modifies the classical processing configuration based on the cross-correlation between the reference and primary microphone. Background noise attenuation is achieved using a cross-correlation sample width that encompasses only the background noise and a matched delay for the adaptive processing. A present limitation of the method is that a minimum time delay between the background noise and desired signal must exist in order for the correlated parts of the desired signal to be separated from the background noise in the crosscorrelation. A simulation yields primary signal recovery which can be predicted from the coherence of the background noise between the channels. Results are compared with two existing methods.

  10. Latent variable method for automatic adaptation to background states in motor imagery BCI

    NASA Astrophysics Data System (ADS)

    Dagaev, Nikolay; Volkova, Ksenia; Ossadtchi, Alexei

    2018-02-01

    Objective. Brain-computer interface (BCI) systems are known to be vulnerable to variabilities in background states of a user. Usually, no detailed information on these states is available even during the training stage. Thus there is a need in a method which is capable of taking background states into account in an unsupervised way. Approach. We propose a latent variable method that is based on a probabilistic model with a discrete latent variable. In order to estimate the model’s parameters, we suggest to use the expectation maximization algorithm. The proposed method is aimed at assessing characteristics of background states without any corresponding data labeling. In the context of asynchronous motor imagery paradigm, we applied this method to the real data from twelve able-bodied subjects with open/closed eyes serving as background states. Main results. We found that the latent variable method improved classification of target states compared to the baseline method (in seven of twelve subjects). In addition, we found that our method was also capable of background states recognition (in six of twelve subjects). Significance. Without any supervised information on background states, the latent variable method provides a way to improve classification in BCI by taking background states into account at the training stage and then by making decisions on target states weighted by posterior probabilities of background states at the prediction stage.

  11. Dual-wavelength digital holographic imaging with phase background subtraction

    NASA Astrophysics Data System (ADS)

    Khmaladze, Alexander; Matz, Rebecca L.; Jasensky, Joshua; Seeley, Emily; Holl, Mark M. Banaszak; Chen, Zhan

    2012-05-01

    Three-dimensional digital holographic microscopic phase imaging of objects that are thicker than the wavelength of the imaging light is ambiguous and results in phase wrapping. In recent years, several unwrapping methods that employed two or more wavelengths were introduced. These methods compare the phase information obtained from each of the wavelengths and extend the range of unambiguous height measurements. A straightforward dual-wavelength phase imaging method is presented which allows for a flexible tradeoff between the maximum height of the sample and the amount of noise the method can tolerate. For highly accurate phase measurements, phase unwrapping of objects with heights higher than the beat (synthetic) wavelength (i.e. the product of the original two wavelengths divided by their difference), can be achieved. Consequently, three-dimensional measurements of a wide variety of biological systems and microstructures become technically feasible. Additionally, an effective method of removing phase background curvature based on slowly varying polynomial fitting is proposed. This method allows accurate volume measurements of several small objects with the same image frame.

  12. Occurrence of mycobacteria in bovine milk samples from both individual and collective bulk tanks at farms and informal markets in the southeast region of Sao Paulo, Brazil

    PubMed Central

    2013-01-01

    Background Mycobacterium spp. is one of the most important species of zoonotic pathogens that can be transmitted from cattle to humans. The presence of these opportunistic, pathogenic bacteria in bovine milk has emerged as a public-health concern, especially among individuals who consume raw milk and related dairy products. To address this concern, the Brazilian control and eradication program focusing on bovine tuberculosis, was established in 2001. However, bovine tuberculosis continues to afflict approximately 1,3 percent of the cattle in Brazil. In the present study, 300 samples of milk from bovine herds, obtained from both individual and collective bulk tanks and informal points of sale, were cultured on Löwenstein-Jensen and Stonebrink media. Polymerase chain reaction (PCR)-based tests and restriction-enzyme pattern analysis were then performed on the colonies exhibiting phenotypes suggestive of Mycobacterium spp., which were characterized as acid-fast bacilli. Results Of the 300 bovine milk samples that were processed, 24 were positively identified as Mycobacterium spp. Molecular identification detected 15 unique mycobacterial species: Mycobacterium bovis, M. gordonae, M. fortuitum, M. intracellulare, M. flavescens, M. duvalii, M. haemophilum, M. immunogenum, M. lentiflavum, M. mucogenicum, M. novocastrense, M. parafortuitum, M. smegmatis, M. terrae and M. vaccae. The isolation of bacteria from the various locations occurred in the following proportions: 9 percent of the individual bulk-tank samples, 7 percent of the collective bulk-tank samples and 8 percent of the informal-trade samples. No statistically significant difference was observed between the presence of Mycobacterium spp. in the three types of samples collected, the milk production profiles, the presence of veterinary assistance and the reported concerns about bovine tuberculosis prevention in the herds. Conclusion The microbiological cultures associated with PCR-based identification tests are

  13. Verification and Trust: Background Investigations Preceding Faculty Appointment

    ERIC Educational Resources Information Center

    Academe, 2004

    2004-01-01

    Many employers in the United States have been initiating or expanding policies requiring background checks of prospective employees. The ability to perform such checks has been abetted by the growth of computerized databases and of commercial enterprises that facilitate access to personal information. Employers now have ready access to public…

  14. Optical polarization: background and camouflage

    NASA Astrophysics Data System (ADS)

    Škerlind, Christina; Hallberg, Tomas; Eriksson, Johan; Kariis, Hans; Bergström, David

    2017-10-01

    Polarimetric imaging sensors in the electro-optical region, already military and commercially available in both the visual and infrared, show enhanced capabilities for advanced target detection and recognition. The capabilities arise due to the ability to discriminate between man-made and natural background surfaces using the polarization information of light. In the development of materials for signature management in the visible and infrared wavelength regions, different criteria need to be met to fulfil the requirements for a good camouflage against modern sensors. In conventional camouflage design, the aimed design of the surface properties of an object is to spectrally match or adapt it to a background and thereby minimizing the contrast given by a specific threat sensor. Examples will be shown from measurements of some relevant materials and how they in different ways affect the polarimetric signature. Dimensioning properties relevant in an optical camouflage from a polarimetric perspective, such as degree of polarization, the viewing or incident angle, and amount of diffuse reflection, mainly in the infrared region, will be discussed.

  15. Addressing adoption and research design decisions simultaneously: the role of value of sample information analysis.

    PubMed

    McKenna, Claire; Claxton, Karl

    2011-01-01

    to estimate the cost-effectiveness of technologies are well developed with increasing experience of their application to inform adoption decisions in a timely way. However, the experience of using similarly explicit methods to inform the associated research decisions is less well developed despite appropriate methods being available with an increasing number of applications in health. The authors demonstrate that evaluation of both adoption and research decisions is feasible within typical time and resource constraints relevant to policy decisions, even in situations in which data are sparse and formal elicitation is required. In addition to demonstrating the application of expected value of sample information (EVSI) in these circumstances, the authors examine and carefully distinguish the impact that the research decision is expected to have on patients while enrolled in the trial, those not enrolled, and once the trial reports. In doing so, the authors are able to account for the range of opportunity cost associated with research and evaluate a number of s including length of follow-up and sample size. The authors also explore the implications for research design of conducting research while the technology is approved for widespread use and whether approval should be withheld until research reports. In doing so, the authors highlight the impact of irrecoverable opportunity costs when the initial costs of a technology are compensated only by later gains in health outcome.

  16. 40 CFR 257.23 - Ground-water sampling and analysis requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... parameters shall be determined after considering the number of samples in the background data base, the data... considering the number of samples in the background data base, the data distribution, and the range of the... of § 257.22(a)(1). (f) The number of samples collected to establish ground-water quality data must be...

  17. 40 CFR 257.23 - Ground-water sampling and analysis requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... parameters shall be determined after considering the number of samples in the background data base, the data... considering the number of samples in the background data base, the data distribution, and the range of the... of § 257.22(a)(1). (f) The number of samples collected to establish ground-water quality data must be...

  18. An interactive ontology-driven information system for simulating background radiation and generating scenarios for testing special nuclear materials detection algorithms

    DOE PAGES

    Sorokine, Alexandre; Schlicher, Bob G.; Ward, Richard C.; ...

    2015-05-22

    This paper describes an original approach to generating scenarios for the purpose of testing the algorithms used to detect special nuclear materials (SNM) that incorporates the use of ontologies. Separating the signal of SNM from the background requires sophisticated algorithms. To assist in developing such algorithms, there is a need for scenarios that capture a very wide range of variables affecting the detection process, depending on the type of detector being used. To provide such a cpability, we developed an ontology-driven information system (ODIS) for generating scenarios that can be used in creating scenarios for testing of algorithms for SNMmore » detection. The ontology-driven scenario generator (ODSG) is an ODIS based on information supplied by subject matter experts and other documentation. The details of the creation of the ontology, the development of the ontology-driven information system, and the design of the web user interface (UI) are presented along with specific examples of scenarios generated using the ODSG. We demonstrate that the paradigm behind the ODSG is capable of addressing the problem of semantic complexity at both the user and developer levels. Compared to traditional approaches, an ODIS provides benefits such as faithful representation of the users' domain conceptualization, simplified management of very large and semantically diverse datasets, and the ability to handle frequent changes to the application and the UI. Furthermore, the approach makes possible the generation of a much larger number of specific scenarios based on limited user-supplied information« less

  19. Hybrid active contour model for inhomogeneous image segmentation with background estimation

    NASA Astrophysics Data System (ADS)

    Sun, Kaiqiong; Li, Yaqin; Zeng, Shan; Wang, Jun

    2018-03-01

    This paper proposes a hybrid active contour model for inhomogeneous image segmentation. The data term of the energy function in the active contour consists of a global region fitting term in a difference image and a local region fitting term in the original image. The difference image is obtained by subtracting the background from the original image. The background image is dynamically estimated from a linear filtered result of the original image on the basis of the varying curve locations during the active contour evolution process. As in existing local models, fitting the image to local region information makes the proposed model robust against an inhomogeneous background and maintains the accuracy of the segmentation result. Furthermore, fitting the difference image to the global region information makes the proposed model robust against the initial contour location, unlike existing local models. Experimental results show that the proposed model can obtain improved segmentation results compared with related methods in terms of both segmentation accuracy and initial contour sensitivity.

  20. Being an Informed Consumer of Health Information and Assessment of Electronic Health Literacy in a National Sample of Internet Users: Validity and Reliability of the e-HLS Instrument.

    PubMed

    Seçkin, Gül; Yeatts, Dale; Hughes, Susan; Hudson, Cassie; Bell, Valarie

    2016-07-11

    The Internet, with its capacity to provide information that transcends time and space barriers, continues to transform how people find and apply information to their own lives. With the current explosion in electronic sources of health information, including thousands of websites and hundreds of mobile phone health apps, electronic health literacy is gaining an increasing prominence in health and medical research. An important dimension of electronic health literacy is the ability to appraise the quality of information that will facilitate everyday health care decisions. Health information seekers explore their care options by gathering information from health websites, blogs, Web-based forums, social networking websites, and advertisements, despite the fact that information quality on the Internet varies greatly. Nonetheless, research has lagged behind in establishing multidimensional instruments, in part due to the evolving construct of health literacy itself. The purpose of this study was to examine psychometric properties of a new electronic health literacy (ehealth literacy) measure in a national sample of Internet users with specific attention to older users. Our paper is motivated by the fact that ehealth literacy is an underinvestigated area of inquiry. Our sample was drawn from a panel of more than 55,000 participants maintained by Knowledge Networks, the largest national probability-based research panel for Web-based surveys. We examined the factor structure of a 19-item electronic Health Literacy Scale (e-HLS) through exploratory factor analysis (EFA) and confirmatory factor analysis, internal consistency reliability, and construct validity on sample of adults (n=710) and a subsample of older adults (n=194). The AMOS graphics program 21.0 was used to construct a measurement model, linking latent factors obtained from EFA with 19 indicators to determine whether this factor structure achieved a good fit with our entire sample and the subsample (age ≥ 60

  1. SCHOOL AND FAMILY BACKGROUND CORRELATES OF CHILDREN'S SCHOOL ANXIETY.

    ERIC Educational Resources Information Center

    DUNN, JAMES A.

    A STUDY WAS MADE OF THE RELATIONSHIP OF CHILDREN'S SCHOOL MENTAL HEALTH PROBLEMS TO (1) THEIR INTELLECTUAL, ACADEMIC, AND SOCIAL PERFORMANCE AND (2) CERTAIN FAMILY, SCHOOL, AND COMMUNITY BACKGROUND VARIABLES. LITERATURE PERTINENT TO THE PROBLEM IS REVIEWED. THE SAMPLE CONSISTED OF 400 ELEMENTARY SCHOOL STUDENTS. GROUP INTELLIGENCE TESTS, AN…

  2. An information theory approach for evaluating earth radiation budget (ERB) measurements - Nonuniform sampling of diurnal longwave flux variations

    NASA Technical Reports Server (NTRS)

    Halyo, Nesim; Direskeneli, Haldun; Barkstrom, Bruce R.

    1991-01-01

    Satellite measurements are subject to a wide range of uncertainties due to their temporal, spatial, and directional sampling characteristics. An information-theory approach is suggested to examine the nonuniform temporal sampling of ERB measurements. The information (i.e., its entropy or uncertainty) before and after the measurements is determined, and information gain (IG) is defined as a reduction in the uncertainties involved. A stochastic model for the diurnal outgoing flux variations that affect the ERB is developed. Using Gaussian distributions for the a priori and measured radiant exitance fields, the IG is obtained by computing the a posteriori covariance. The IG for the monthly outgoing flux measurements is examined for different orbital parameters and orbital tracks, using the Earth Observing System orbital parameters as specific examples. Variations in IG due to changes in the orbit's inclination angle and the initial ascending node local time are investigated.

  3. Processes in scientific workflows for information seeking related to physical sample materials

    NASA Astrophysics Data System (ADS)

    Ramdeen, S.

    2014-12-01

    The majority of State Geological Surveys have repositories containing cores, cuttings, fossils or other physical sample material. State surveys maintain these collections to support their own research as well as the research conducted by external users from other organizations. This includes organizations such as government agencies (state and federal), academia, industry and the public. The preliminary results presented in this paper will look at the research processes of these external users. In particular: how they discover, access and use digital surrogates, which they use to evaluate and access physical items in these collections. Data such as physical samples are materials that cannot be completely replaced with digital surrogates. Digital surrogates may be represented as metadata, which enable discovery and ultimately access to these samples. These surrogates may be found in records, databases, publications, etc. But surrogates do not completely prevent the need for access to the physical item as they cannot be subjected to chemical testing and/or other similar analysis. The goal of this research is to document the various processes external users perform in order to access physical materials. Data for this study will be collected by conducting interviews with these external users. During the interviews, participants will be asked to describe the workflow that lead them to interact with state survey repositories, and what steps they took afterward. High level processes/categories of behavior will be identified. These processes will be used in the development of an information seeking behavior model. This model may be used to facilitate the development of management tools and other aspects of cyberinfrastructure related to physical samples.

  4. 78 FR 79009 - Proposed Information Collection; Radiation Sampling and Exposure Records (Pertains to Underground...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ...The Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a pre-clearance consultation program to provide the general public and Federal agencies with an opportunity to comment on proposed and continuing collections of information in accordance with the Paperwork Reduction Act of 1995, 44 U.S.C. 3506(c)(2)(A). This program helps to assure that requested data can be provided in the desired format, reporting burden (time and financial resources) is minimized, collection instruments are clearly understood, and the impact of collection requirements on respondents can be properly assessed. Currently, the Mine Safety and Health Administration (MSHA) is soliciting comments concerning the proposed information collection for updating Radiation Sampling and Exposure Records.

  5. Guidelines for Design and Sampling for Cyanobacterial Toxin and Taste-and-Odor Studies in Lakes and Reservoirs

    USGS Publications Warehouse

    Graham, Jennifer L.; Loftin, Keith A.; Ziegler, Andrew C.; Meyer, Michael T.

    2008-01-01

    Cyanobacteria and associated toxins and taste-and-odor compounds are of increasing environmental concern. However, consistent guidelines for the development of studies assessing cyanobacterial toxins and taste-and-odor compounds presently are not available. This report provides guidance for the development of scientific studies of cyanobacteria and associated by-products in lakes and reservoirs. Topics include: background information on cyanobacteria, toxins, and taste-and-odor compounds; spatial and temporal considerations that are unique to the cyanobacteria in lakes and reservoirs; common study types, objectives, and approaches for studies of cyanobacteria and associated toxins and taste-and-odor compounds; general guidelines for collecting samples; and information on sample handling, preparation, processing, and shipping.

  6. Advances in imaging secondary ion mass spectrometry for biological samples

    DOE PAGES

    Boxer, Steven G.; Kraft, Mary L.; Weber, Peter K.

    2008-12-16

    Imaging mass spectrometry combines the power of mass spectrometry to identify complex molecules based on mass with sample imaging. Recent advances in secondary ion mass spectrometry have improved sensitivity and spatial resolution, so that these methods have the potential to bridge between high-resolution structures obtained by X-ray crystallography and cyro-electron microscopy and ultrastructure visualized by conventional light microscopy. Following background information on the method and instrumentation, we address the key issue of sample preparation. Because mass spectrometry is performed in high vacuum, it is essential to preserve the lateral organization of the sample while removing bulk water, and this hasmore » been a major barrier for applications to biological systems. Furthermore, recent applications of imaging mass spectrometry to cell biology, microbial communities, and biosynthetic pathways are summarized briefly, and studies of biological membrane organization are described in greater depth.« less

  7. info-gibbs: a motif discovery algorithm that directly optimizes information content during sampling.

    PubMed

    Defrance, Matthieu; van Helden, Jacques

    2009-10-15

    Discovering cis-regulatory elements in genome sequence remains a challenging issue. Several methods rely on the optimization of some target scoring function. The information content (IC) or relative entropy of the motif has proven to be a good estimator of transcription factor DNA binding affinity. However, these information-based metrics are usually used as a posteriori statistics rather than during the motif search process itself. We introduce here info-gibbs, a Gibbs sampling algorithm that efficiently optimizes the IC or the log-likelihood ratio (LLR) of the motif while keeping computation time low. The method compares well with existing methods like MEME, BioProspector, Gibbs or GAME on both synthetic and biological datasets. Our study shows that motif discovery techniques can be enhanced by directly focusing the search on the motif IC or the motif LLR. http://rsat.ulb.ac.be/rsat/info-gibbs

  8. Informed consent for MRI and fMRI research: Analysis of a sample of Canadian consent documents

    PubMed Central

    2011-01-01

    Background Research ethics and the measures deployed to ensure ethical oversight of research (e.g., informed consent forms, ethics review) are vested with extremely important ethical and practical goals. Accordingly, these measures need to function effectively in real-world research and to follow high level standards. Methods We examined approved consent forms for Magnetic Resonance Imaging (MRI) and functional Magnetic Resonance Imaging (fMRI) studies approved by Canadian research ethics boards (REBs). Results We found evidence of variability in consent forms in matters of physical and psychological risk reporting. Approaches used to tackle the emerging issue of incidental findings exposed extensive variability between and within research sites. Conclusion The causes of variability in approved consent forms and studies need to be better understood. However, mounting evidence of administrative and practical hurdles within current ethics governance systems combined with potential sub-optimal provision of information to and protection of research subjects support other calls for more scrutiny of research ethics practices and applicable revisions. PMID:21235768

  9. Postmastectomy Information Needs and Information-seeking Motives for Women with Breast Cancer

    PubMed Central

    Latifi, Masoome; Salimi, Sohrab; Barahmand, Nilofar; Fahimnia, Fateme; Allahbakhshian Farsani, Leili

    2018-01-01

    Background: Health information-seeking behavior is a key concept in the empowerment of women with breast cancer after mastectomy for self-care management. Thus, a real understanding of their information needs and their information-seeking behavior may open up new opportunities for their postsurgery cares. The current research was conducted to identify the information needs and information-seeking motives of women with breast cancer after mastectomy. Materials and Methods: This is an applied qualitative research. Samples included 17 women with breast cancer after mastectomy selected from two hospitals of Shahid Mohammadi and Persian Gulf and Omid Central Chemotherapy in Bandar Abbas. Data were collected using semi-structured interview on winter 2014 and analyzed using qualitative content analysis method. Results: Three basic contents were extracted including information needs related to mental health, physical health related to disease and personal daily activities along with their subcategories, and representing common experience and perception of mastectomized women seeking for health information. Furthermore, hope, self-esteem, return to life, and available social support resources were expressed as the main information-seeking motives. Conclusion: Considering research findings, mastectomized women need to receive information in wide range of health and thus pursue purposeful behavior. Hence, it is necessary that required actions and measures are taken by health-care authorities, especially institutions responsible for women health, to support and meet information needs of the patients considering their information-seeking motives. PMID:29862224

  10. Six faint gamma-ray pulsars seen with the Fermi Large Area Telescope: Towards a sample blending into the background

    DOE PAGES

    Hou, X.; Smith, D. A.; Guillemot, L.; ...

    2014-10-14

    Context. Here, GeV gamma-ray pulsations from over 140 pulsars have been characterized using the Fermi Large Area Telescope, enabling improved understanding of the emission regions within the neutron star magnetospheres, and the contributions of pulsars to high energy electrons and diffuse gamma rays in the Milky Way. The first gamma-ray pulsars to be detected were the most intense and/or those with narrow pulses. Aims. As the Fermi mission progresses, progressively fainter objects can be studied. In addition to more distant pulsars (thus probing a larger volume of the Galaxy), or ones in high background regions (thus improving the sampling uniformitymore » across the Galactic plane), we detect pulsars with broader pulses or lower luminosity. Adding pulsars to our catalog with inclination angles that are rare in the observed sample, and/or with lower spindown power, will reduce the bias in the currently known gamma-ray pulsar population. Methods. We use rotation ephemerides derived from radio observations to phase-fold gamma rays recorded by the Fermi Large Area Telescope, to then determine the pulse profile properties. Spectral analysis provides the luminosities and, when the signal-to-noise ratio allows, the cutoff energies. We constrain the pulsar distances by different means in order to minimize the luminosity uncertainties. Results. We present six new gamma-ray pulsars with an eclectic mix of properties. Three are young, and three are recycled. They include the farthest, the lowest power, two of the highest duty-cycle pulsars seen, and only the fourth young gamma-ray pulsar with a radio interpulse. Finally, we discuss the biases existing in the current gamma-ray pulsar catalog, and steps to be taken to mitigate the bias.« less

  11. Reevalution of background iodine-129 concentrations in water from the Snake River Plain Aquifer, Idaho, 2003

    USGS Publications Warehouse

    Cecil, L. DeWayne; Hall, L. Flint; Green, Jaromy R.

    2003-01-01

    Background concentrations of iodine-129 (129I, half-life = 15.7 million years) resulting from natural production in the earth?s atmosphere, in situ production in the earth by spontaneous fission of uranium-238(238U), and fallout from nuclear weapons tests conducted in the 1950s and 1960s were reevaluated on the basis of 52 analyses of ground- and surface-water samples collected from the eastern Snake River Plain in southeastern Idaho. The background concentration estimated using the results of a subset of 30 ground-water samples analyzed in this reevaluation is 5.4 attocuries per liter (aCi/L; 1 aCi = 10-18 curies) and the 95-percent nonparametric confidence interval is 5.2 to 10.0 aCi/L. In a previous study, a background 129I concentration was estimated on the basis of analyses of water samples from 16 sites on or tributary to the eastern Snake River Plain. At the 99-percent confidence level, background concentrations of 129I in that study were less than or equal to 8.2 aCi/L. During 1993?94, 34 water samples from 32 additional sites were analyzed for 129I to better establish the background concentrations in surface and ground water from the eastern Snake River Plain that is presumed to be unaffected by wastedisposal practices at the Idaho National Engineering and Environmental Laboratory (INEEL). Surface water contained larger 129I concentrations than water from springs and wells contained. Because surface water is more likely to be affected by anthropogenic fallout and evapotranspiration, background 129I concentrations were estimated in the current research using the laboratory results of ground-water samples that were assumed to be unaffected by INEEL disposal practices.

  12. In-mine testing of a natural background sensor, part B

    NASA Technical Reports Server (NTRS)

    Martzloff, F. D.

    1981-01-01

    The capability of a natural background sensor for measuring the thickness of top coal on a longwall face was examined. The limitations on the time during which tests could be performed, and the roof conditions, did not produce readings of top coal measurements during the shearer operation. It was demonstrated that the system is capable to survive operating conditions in the mine environment, while the static tests confirmed that the natural background sensor approach is a valid method of measuring top coal thickness in mines where the roof rock provides a constant radiation level. It is concluded that the practical results will improve sequent development of an integrated vertical control system which is information from the natural background system.

  13. Ultra-low background mass spectrometry for rare-event searches

    NASA Astrophysics Data System (ADS)

    Dobson, J.; Ghag, C.; Manenti, L.

    2018-01-01

    Inductively Coupled Plasma Mass Spectrometry (ICP-MS) allows for rapid, high-sensitivity determination of trace impurities, notably the primordial radioisotopes 238U and 232Th, in candidate materials for low-background rare-event search experiments. We describe the setup and characterisation of a dedicated low-background screening facility at University College London where we operate an Agilent 7900 ICP-MS. The impact of reagent and carrier gas purity is evaluated and we show that twice-distilled ROMIL-SpATM-grade nitric acid and zero-grade Ar gas delivers similar sensitivity to ROMIL-UpATM-grade acid and research-grade gas. A straightforward procedure for sample digestion and analysis of materials with U/Th concentrations down to 10 ppt g/g is presented. This includes the use of 233U and 230Th spikes to correct for signal loss from a range of sources and verification of 238U and 232Th recovery through digestion and analysis of a certified reference material with a complex sample matrix. Finally, we demonstrate assays and present results from two sample preparation and assay methods: a high-sensitivity measurement of ultra-pure Ti using open digestion techniques, and a closed vessel microwave digestion of a nickel-chromium-alloy using a multi-acid mixture.

  14. Sample Collection Information Document for Pathogens and Biotoxins − Companion to Standardized Analytical Methods for Environmental Restoration Following Homeland Security Events (SAM) Revision 5.0

    EPA Pesticide Factsheets

    Sample Collection Information Document is intended to provide sampling information to be used during site assessment, remediation and clearance activities following a biological or biotoxin contamination incident.

  15. C5-C12 volatile organic compounds at roadside, residential, and background locations in Ankara, Turkey: temporal and spatial variations and sources.

    PubMed

    Kuntasal, Oznur Oğuz; Kilavuz, Seda Aslan; Karman, Deniz; Wang, Daniel; Tuncel, Gürdal

    2013-10-01

    Concentrations of 91 volatile organic compounds (VOCs) ranging from C5 to C12 were measured at three sites in Ankara, the capital of Turkey, in the summer of 2003 and winter of 2004. Samples were collected at roadside, residential and background stations at consecutive 4-hr intervals over a 24-hr period for six weeks in each season. Air samples were collected onto cartridges packed with Tenax TA and Carbopack B resins and analyzed by thermal desorption, followed by gas chromatography coupled to a mass selective detector (GC/MSD). Time resolved data provided information on ambient levels, temporal and spatial variations and sources of VOCs in Ankara. Toluene is the most abundant compound at all sites with and average concentration of 13.1 ?g m(-3). The mean concentrations of benzene are 12.6, 5.2, and 2.4 ?g m(-3) during winter at roadside, residential and background stations, respectively. Diurnal variation in the data together with toluene to benzene concentration ratio (T:B) that is close to 2.0 indicated the influence of traffic related emissions at residential and roadside stations during winter season. Higher T:B ratio observed at residential and background stations during summer period and correlation analysis indicated additional VOC sources. Temporal variations and low m,p-xylene to ethylbenzene ratio (mpX:E) indicated that transported air mass is the major VOC source influencing VOC concentrations measured at the background station.

  16. Influence of background music on work attention in clients with chronic schizophrenia.

    PubMed

    Shih, Yi-Nuo; Chen, Chi-Sheng; Chiang, Hsin-Yu; Liu, Chien-Hsiou

    2015-01-01

    Work attention in persons with chronic schizophrenia is an important issue in vocational rehabilitation. Some of the research literature indicates that background music may influence visual attention performance. Based on the theory of occupational therapy, environmental sounds, colors and decorations may affect individual performance, this study thus examined the influence of music on work attention in persons with schizophrenia. Participants were recruited from a halfway house in Taipei. Forty-nine (49) patients with chronic schizophrenia volunteered. They had been accepted into vocational rehabilitation and a work-seeking program. The sample included 20 females and 29 males. The participant ages ranged between 29 and 63 years old, and their average age was 47 years old. Using a randomized controlled trial (RCT) study, the participants were assigned to one of three conditions: quiet environment as the control group (n= 16), classical light music as background music (n= 16), and popular music as background music (n= 17). For Group 1 (control group/quiet environment), there was no significant variance (sig = 0.172). For Group 2 (Classical light music), the intervention revealed significant variance (sig = 0.071*). For Group 3 (popular music), the intervention had significant variance (sig = 0.048**). The introduction of background music tended to increase attention test scores of persons with schizophrenia. Moreover, the increase in test attention scores was statistically significant when popular music was played in the background. This result suggested that background music may improve attention performance of persons with chronic schizophrenia. Future research is required with a larger sample size to support the study results.

  17. 75 FR 79033 - Proposed Extension of Existing Information Collection; Radiation Sampling and Exposure Records...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ...The Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a pre-clearance consultation program to provide the general public and Federal agencies with an opportunity to comment on proposed and continuing collections of information in accordance with the Paperwork Reduction Act of 1995 [44 U.S.C. 3506(c)(2)(A)]. This program helps to assure that requested data can be provided in the desired format, reporting burden (time and financial resources) is minimized, collection instruments are clearly understood, and the impact of collection requirements on respondents can be properly assessed. Currently, the Mine Safety and Health Administration (MSHA) is soliciting comments concerning the extension of the information collection for Radiation Sampling and Exposure Records, 30 CFR 57.5037 and 57.5040.

  18. 75 FR 80072 - Proposed Extension of Existing Information Collection; Radiation Sampling and Exposure Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ...The Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a pre-clearance consultation program to provide the general public and Federal agencies with an opportunity to comment on proposed and continuing collections of information in accordance with the Paperwork Reduction Act of 1995 [44 U.S.C. 3506(c)(2)(A)]. This program helps to assure that requested data can be provided in the desired format, reporting burden (time and financial resources) is minimized, collection instruments are clearly understood, and the impact of collection requirements on respondents can be properly assessed. Currently, the Mine Safety and Health Administration (MSHA) is soliciting comments concerning the extension of the information collection for Radiation Sampling and Exposure Records, 30 CFR 57.5037 and 57.5040.

  19. An Effective Method for Modeling Two-dimensional Sky Background of LAMOST

    NASA Astrophysics Data System (ADS)

    Haerken, Hasitieer; Duan, Fuqing; Zhang, Jiannan; Guo, Ping

    2017-06-01

    Each CCD of LAMOST accommodates 250 spectra, while about 40 are used to observe sky background during real observations. How to estimate the unknown sky background information hidden in the observed 210 celestial spectra by using the known 40 sky spectra is the problem we solve. In order to model the sky background, usually a pre-observation is performed with all fibers observing sky background. We use the observed 250 skylight spectra as training data, where those observed by the 40 fibers are considered as a base vector set. The Locality-constrained Linear Coding (LLC) technique is utilized to represent the skylight spectra observed by the 210 fibers with the base vector set. We also segment each spectrum into small parts, and establish the local sky background model for each part. Experimental results validate the proposed method, and show the local model is better than the global model.

  20. Inhibition of recombinase polymerase amplification by background DNA: a lateral flow-based method for enriching target DNA.

    PubMed

    Rohrman, Brittany; Richards-Kortum, Rebecca

    2015-02-03

    Recombinase polymerase amplification (RPA) may be used to detect a variety of pathogens, often after minimal sample preparation. However, previous work has shown that whole blood inhibits RPA. In this paper, we show that the concentrations of background DNA found in whole blood prevent the amplification of target DNA by RPA. First, using an HIV-1 RPA assay with known concentrations of nonspecific background DNA, we show that RPA tolerates more background DNA when higher HIV-1 target concentrations are present. Then, using three additional assays, we demonstrate that the maximum amount of background DNA that may be tolerated in RPA reactions depends on the DNA sequences used in the assay. We also show that changing the RPA reaction conditions, such as incubation time and primer concentration, has little effect on the ability of RPA to function when high concentrations of background DNA are present. Finally, we develop and characterize a lateral flow-based method for enriching the target DNA concentration relative to the background DNA concentration. This sample processing method enables RPA of 10(4) copies of HIV-1 DNA in a background of 0-14 μg of background DNA. Without lateral flow sample enrichment, the maximum amount of background DNA tolerated is 2 μg when 10(6) copies of HIV-1 DNA are present. This method requires no heating or other external equipment, may be integrated with upstream DNA extraction and purification processes, is compatible with the components of lysed blood, and has the potential to detect HIV-1 DNA in infant whole blood with high proviral loads.

  1. TIMSS 2011 User Guide for the International Database. Supplement 2: National Adaptations of International Background Questionnaires

    ERIC Educational Resources Information Center

    Foy, Pierre, Ed.; Arora, Alka, Ed.; Stanco, Gabrielle M., Ed.

    2013-01-01

    This supplement describes national adaptations made to the international version of the TIMSS 2011 background questionnaires. This information provides users with a guide to evaluate the availability of internationally comparable data for use in secondary analyses involving the TIMSS 2011 background variables. Background questionnaire adaptations…

  2. Nontraditional Males: Familial Background, Life Satisfaction, and Personality Characteristics.

    ERIC Educational Resources Information Center

    Rosenwasser, Shirley Miller; Patterson, William

    Research indicates that the family roles of men are slowly changing, with a small minority of those sampled having primary childcare/household duties. To examine the background, life satisfaction, motives, and personality traits of such men, 16 married, male adults, whose wives were employed outside the home, and who had over 50% of the…

  3. Background odour induces adaptation and sensitization of olfactory receptors in the antennae of houseflies.

    PubMed

    Kelling, F J; Ialenti, F; Den Otter, C J

    2002-06-01

    The presence of background odour was found to have a small but significant effect on the sensitivity of the antennal olfactory system of houseflies, Musca domestica Linnaeus (Diptera: Muscidae), to new pulses of odour. We show that cross-adaptation and cross-sensitization between a background odour of (+/-)-1-octen-3-ol and pulses of (+/-)-1-octen-3-ol, 2-pentanone and R-(+)-limonene can occur, confirming that olfactory receptor cells are sensitive to different odours. Background odour can increase the responses to low concentration odour pulses and decrease the responses to higher concentration odour pulses. It is suggested that background odour has a larger effect on olfactory receptor cells that respond with a tonic increase of spike frequency, giving information about the level of odour concentration, i.e. the 'static' environment. Cells that respond in a phasic way only provide information on the dynamics of the olfactory environment.

  4. Extracting information in spike time patterns with wavelets and information theory.

    PubMed

    Lopes-dos-Santos, Vítor; Panzeri, Stefano; Kayser, Christoph; Diamond, Mathew E; Quian Quiroga, Rodrigo

    2015-02-01

    We present a new method to assess the information carried by temporal patterns in spike trains. The method first performs a wavelet decomposition of the spike trains, then uses Shannon information to select a subset of coefficients carrying information, and finally assesses timing information in terms of decoding performance: the ability to identify the presented stimuli from spike train patterns. We show that the method allows: 1) a robust assessment of the information carried by spike time patterns even when this is distributed across multiple time scales and time points; 2) an effective denoising of the raster plots that improves the estimate of stimulus tuning of spike trains; and 3) an assessment of the information carried by temporally coordinated spikes across neurons. Using simulated data, we demonstrate that the Wavelet-Information (WI) method performs better and is more robust to spike time-jitter, background noise, and sample size than well-established approaches, such as principal component analysis, direct estimates of information from digitized spike trains, or a metric-based method. Furthermore, when applied to real spike trains from monkey auditory cortex and from rat barrel cortex, the WI method allows extracting larger amounts of spike timing information. Importantly, the fact that the WI method incorporates multiple time scales makes it robust to the choice of partly arbitrary parameters such as temporal resolution, response window length, number of response features considered, and the number of available trials. These results highlight the potential of the proposed method for accurate and objective assessments of how spike timing encodes information. Copyright © 2015 the American Physiological Society.

  5. A Study on Mutil-Scale Background Error Covariances in 3D-Var Data Assimilation

    NASA Astrophysics Data System (ADS)

    Zhang, Xubin; Tan, Zhe-Min

    2017-04-01

    The construction of background error covariances is a key component of three-dimensional variational data assimilation. There are different scale background errors and interactions among them in the numerical weather Prediction. However, the influence of these errors and their interactions cannot be represented in the background error covariances statistics when estimated by the leading methods. So, it is necessary to construct background error covariances influenced by multi-scale interactions among errors. With the NMC method, this article firstly estimates the background error covariances at given model-resolution scales. And then the information of errors whose scales are larger and smaller than the given ones is introduced respectively, using different nesting techniques, to estimate the corresponding covariances. The comparisons of three background error covariances statistics influenced by information of errors at different scales reveal that, the background error variances enhance particularly at large scales and higher levels when introducing the information of larger-scale errors by the lateral boundary condition provided by a lower-resolution model. On the other hand, the variances reduce at medium scales at the higher levels, while those show slight improvement at lower levels in the nested domain, especially at medium and small scales, when introducing the information of smaller-scale errors by nesting a higher-resolution model. In addition, the introduction of information of larger- (smaller-) scale errors leads to larger (smaller) horizontal and vertical correlation scales of background errors. Considering the multivariate correlations, the Ekman coupling increases (decreases) with the information of larger- (smaller-) scale errors included, whereas the geostrophic coupling in free atmosphere weakens in both situations. The three covariances obtained in above work are used in a data assimilation and model forecast system respectively, and then the

  6. Saudi Arabia: Background and U.S. Relations

    DTIC Science & Technology

    2015-04-29

    23, 2013. 6 Background information on Saudi cabinet members is available at http://www.saudiembassy.net/about/ Biographies - of-Ministers.aspx. Saudi...territories it occupied in 1967, (2) agree to the establishment of a Palestinian state with a capital in East Jerusalem , and provide for the (3) “[a...compromise on Palestinian sovereignty in Jerusalem .” Elhanan Miller, “Arab ministers back Abbas in rejecting ‘Jewish’ Israel,” Times of Israel, January

  7. Background for Builders--Related Science and Trade Information for the Building Trades.

    ERIC Educational Resources Information Center

    Lucas, Joseph

    Primarily intended for instructors but also useful to students, this guide provides a set of lessons (interlaced with humorous phrases and cartoons) for teaching fundamental information for the building trades. Each lesson contains objectives, related information, and a review or summary. Unit I is a brief, humorous message to the student on the…

  8. Florida's Information Policy: Problems and Issues in the Information Age.

    ERIC Educational Resources Information Center

    Florida State Legislature, Tallahassee.

    This report examines the major issues arising from the impact of information technology on the creation of government information and its storage, processing, and recordkeeping, based on information gathered through a literature search, several mailed questionnaires, and three public hearings. An outline of the background of the information policy…

  9. Environmental literacy based on educational background

    NASA Astrophysics Data System (ADS)

    Agfar, A.; Munandar, A.; Surakusumah, W.

    2018-05-01

    This research aims to examine attitude, knowledge and cognitive skill. To collect data we used survey method, was conducted in Pahawang, Lampung. Respondents of this research are coastal society of Pahawang, 114 participants determined using purposive sampling, from two areas in the village, Pahawang and Penggetahan. Data were analyzed using both quantitative and descriptive. Environmental literacy of the society which is primary school graduate is moderate category (85.61), consist of 38.90% in low category and 61.10% in moderate category. Environmental literacy of junior high school graduate is moderate (99.36), consist of 12% in low category, 76% in moderate category and 12% in high category. Environmental literacy of senior high school graduate is moderate (108.85), consist of 84.90% moderate category and 15.10% in high category. But, undergraduate society is high category (118.53). Details 0% low category 52.94% moderate category and 47.06% in high category. This finding research has revelaed that the educational background affects the level of environmental literacy. This finding research has revealed that the educational background affects the level of environmental literacy.

  10. Image reconstructions from super-sampled data sets with resolution modeling in PET imaging.

    PubMed

    Li, Yusheng; Matej, Samuel; Metzler, Scott D

    2014-12-01

    Spatial resolution in positron emission tomography (PET) is still a limiting factor in many imaging applications. To improve the spatial resolution for an existing scanner with fixed crystal sizes, mechanical movements such as scanner wobbling and object shifting have been considered for PET systems. Multiple acquisitions from different positions can provide complementary information and increased spatial sampling. The objective of this paper is to explore an efficient and useful reconstruction framework to reconstruct super-resolution images from super-sampled low-resolution data sets. The authors introduce a super-sampling data acquisition model based on the physical processes with tomographic, downsampling, and shifting matrices as its building blocks. Based on the model, we extend the MLEM and Landweber algorithms to reconstruct images from super-sampled data sets. The authors also derive a backprojection-filtration-like (BPF-like) method for the super-sampling reconstruction. Furthermore, they explore variant methods for super-sampling reconstructions: the separate super-sampling resolution-modeling reconstruction and the reconstruction without downsampling to further improve image quality at the cost of more computation. The authors use simulated reconstruction of a resolution phantom to evaluate the three types of algorithms with different super-samplings at different count levels. Contrast recovery coefficient (CRC) versus background variability, as an image-quality metric, is calculated at each iteration for all reconstructions. The authors observe that all three algorithms can significantly and consistently achieve increased CRCs at fixed background variability and reduce background artifacts with super-sampled data sets at the same count levels. For the same super-sampled data sets, the MLEM method achieves better image quality than the Landweber method, which in turn achieves better image quality than the BPF-like method. The authors also demonstrate

  11. 40 CFR 258.53 - Ground-water sampling and analysis requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... considering the number of samples in the background data base, the data distribution, and the range of the... the background data base, the data distribution, and the range of the concentration values for each... samples collected to establish ground-water quality data must be consistent with the appropriate...

  12. 40 CFR 258.53 - Ground-water sampling and analysis requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... considering the number of samples in the background data base, the data distribution, and the range of the... the background data base, the data distribution, and the range of the concentration values for each... samples collected to establish ground-water quality data must be consistent with the appropriate...

  13. Simple street tree sampling

    Treesearch

    David J. Nowak; Jeffrey T. Walton; James Baldwin; Jerry Bond

    2015-01-01

    Information on street trees is critical for management of this important resource. Sampling of street tree populations provides an efficient means to obtain street tree population information. Long-term repeat measures of street tree samples supply additional information on street tree changes and can be used to report damages from catastrophic events. Analyses of...

  14. Infrared image background modeling based on improved Susan filtering

    NASA Astrophysics Data System (ADS)

    Yuehua, Xia

    2018-02-01

    When SUSAN filter is used to model the infrared image, the Gaussian filter lacks the ability of direction filtering. After filtering, the edge information of the image cannot be preserved well, so that there are a lot of edge singular points in the difference graph, increase the difficulties of target detection. To solve the above problems, the anisotropy algorithm is introduced in this paper, and the anisotropic Gauss filter is used instead of the Gauss filter in the SUSAN filter operator. Firstly, using anisotropic gradient operator to calculate a point of image's horizontal and vertical gradient, to determine the long axis direction of the filter; Secondly, use the local area of the point and the neighborhood smoothness to calculate the filter length and short axis variance; And then calculate the first-order norm of the difference between the local area of the point's gray-scale and mean, to determine the threshold of the SUSAN filter; Finally, the built SUSAN filter is used to convolution the image to obtain the background image, at the same time, the difference between the background image and the original image is obtained. The experimental results show that the background modeling effect of infrared image is evaluated by Mean Squared Error (MSE), Structural Similarity (SSIM) and local Signal-to-noise Ratio Gain (GSNR). Compared with the traditional filtering algorithm, the improved SUSAN filter has achieved better background modeling effect, which can effectively preserve the edge information in the image, and the dim small target is effectively enhanced in the difference graph, which greatly reduces the false alarm rate of the image.

  15. Improving the limits of detection of low background alpha emission measurements

    NASA Astrophysics Data System (ADS)

    McNally, Brendan D.; Coleman, Stuart; Harris, Jack T.; Warburton, William K.

    2018-01-01

    Alpha particle emission - even at extremely low levels - is a significant issue in the search for rare events (e.g., double beta decay, dark matter detection). Traditional measurement techniques require long counting times to measure low sample rates in the presence of much larger instrumental backgrounds. To address this, a commercially available instrument developed by XIA uses pulse shape analysis to discriminate alpha emissions produced by the sample from those produced by other surfaces of the instrument itself. Experience with this system has uncovered two residual sources of background: cosmogenics and radon emanation from internal components. An R&D program is underway to enhance the system and extend the pulse shape analysis technique further, so that these residual sources can be identified and rejected as well. In this paper, we review the theory of operation and pulse shape analysis techniques used in XIA's alpha counter, and briefly explore data suggesting the origin of the residual background terms. We will then present our approach to enhance the system's ability to identify and reject these terms. Finally, we will describe a prototype system that incorporates our concepts and demonstrates their feasibility.

  16. A method to characterise site, urban and regional ambient background radiation.

    PubMed

    Passmore, C; Kirr, M

    2011-03-01

    Control dosemeters are routinely provided to customers to monitor the background radiation so that it can be subtracted from the gross response of the dosemeter to arrive at the occupational dose. Landauer, the largest dosimetry processor in the world with subsidiaries in Australia, Brazil, China, France, Japan, Mexico and the UK, has clients in approximately 130 countries. The Glenwood facility processes over 1.1 million controls per year. This network of clients around the world provides a unique ability to monitor the world's ambient background radiation. Control data can be mined to provide useful historical information regarding ambient background rates and provide a historical baseline for geographical areas. Historical baseline can be used to provide site or region-specific background subtraction values, document the variation in ambient background radiation around a client's site or provide a baseline for measuring the efficiency of clean-up efforts in urban areas after a dirty bomb detonation.

  17. Lunar Sample Compendium

    NASA Technical Reports Server (NTRS)

    Meyer, C.

    2009-01-01

    The Lunar Sample Compendium is a succinct summary of what has been learned from the study of Apollo and Luna samples of the Moon. Basic information is compiled, sample-by-sample, in the form of an advanced catalog in order to provide a basic description of each sample. Information presented is carefully attributed to the original source publication, thus the Compendium also serves as a ready access to the now vast scientific literature pertaining to lunar smples. The Lunar Sample Compendium is a work in progress (and may always be). Future plans include: adding sections on additional samples, adding new thin section photomicrographs, replacing the faded photographs with newly digitized photos from the original negatives, attempting to correct the age data using modern decay constants, adding references to each section, and adding an internal search engine.

  18. The Alaskan mineral resource assessment program; background information to accompany folio of geologic and mineral resource maps of the Ambler River Quadrangle, Alaska

    USGS Publications Warehouse

    Mayfield, Charles F.; Tailleur, I.L.; Albert, N.R.; Ellersieck, Inyo; Grybeck, Donald; Hackett, S.W.

    1983-01-01

    The Ambler River quadrangle, consisting of 14,290 km2 (5,520 mi2) in northwest Alaska, was investigated by an interdisciplinary research team for the purpose of assessing the mineral resource potential of the quadrangle. This report provides background information for a folio of maps on the geology, reconnaissance geochemistry, aeromagnetics, Landsat imagery, and mineral resource evaluation of the quadrangle. A summary of the geologic history, radiometric dates, and fossil localities and a comprehensive bibliography are also included. The quadrangle contains jade reserves, now being mined, and potentially significant resources of copper, zinc, lead, and silver.

  19. Focal plane infrared readout circuit with automatic background suppression

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Yang, Guang (Inventor); Sun, Chao (Inventor); Shaw, Timothy J. (Inventor); Wrigley, Chris J. (Inventor)

    2002-01-01

    A circuit for reading out a signal from an infrared detector includes a current-mode background-signal subtracting circuit having a current memory which can be enabled to sample and store a dark level signal from the infrared detector during a calibration phase. The signal stored by the current memory is subtracted from a signal received from the infrared detector during an imaging phase. The circuit also includes a buffered direct injection input circuit and a differential voltage readout section. By performing most of the background signal estimation and subtraction in a current mode, a low gain can be provided by the buffered direct injection input circuit to keep the gain of the background signal relatively small, while a higher gain is provided by the differential voltage readout circuit. An array of such readout circuits can be used in an imager having an array of infrared detectors. The readout circuits can provide a high effective handling capacity.

  20. Information and Knowledge: An Evolutionary Framework for Information Science

    ERIC Educational Resources Information Center

    Bates, Marcia J.

    2005-01-01

    Background: Many definitions of information, knowledge, and data have been suggested throughout the history of information science. In this article, the objective is to provide definitions that are usable for the physical, biological, and social meanings of the terms, covering the various senses important to our field. Argument: Information 1 is…

  1. Chromatographic background drift correction coupled with parallel factor analysis to resolve coelution problems in three-dimensional chromatographic data: quantification of eleven antibiotics in tap water samples by high-performance liquid chromatography coupled with a diode array detector.

    PubMed

    Yu, Yong-Jie; Wu, Hai-Long; Fu, Hai-Yan; Zhao, Juan; Li, Yuan-Na; Li, Shu-Fang; Kang, Chao; Yu, Ru-Qin

    2013-08-09

    Chromatographic background drift correction has been an important field of research in chromatographic analysis. In the present work, orthogonal spectral space projection for background drift correction of three-dimensional chromatographic data was described in detail and combined with parallel factor analysis (PARAFAC) to resolve overlapped chromatographic peaks and obtain the second-order advantage. This strategy was verified by simulated chromatographic data and afforded significant improvement in quantitative results. Finally, this strategy was successfully utilized to quantify eleven antibiotics in tap water samples. Compared with the traditional methodology of introducing excessive factors for the PARAFAC model to eliminate the effect of background drift, clear improvement in the quantitative performance of PARAFAC was observed after background drift correction by orthogonal spectral space projection. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Development of an Ultra-Low Background Liquid Scintillation Counter for Trace Level Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Erchinger, Jennifer L.; Orrell, John L.; Aalseth, Craig E.

    2015-09-01

    Low-level liquid scintillation counting (LSC) has been established as one of the radiation detection techniques useful in elucidating environmental processes and environmental monitoring around nuclear facilities. The Ultra-Low Background Liquid Scintillation Counter (ULB-LSC) under construction in the Shallow Underground Laboratory at Pacific Northwest National Laboratory aims to further reduce the MDAs and/or required sample processing. Through layers of passive shielding in conjunction with an active veto and 30 meters water equivalent overburden, the background reduction is expected to be 10 to 100 times below typical analytic low-background liquid scintillation systems. Simulations have shown an expected background of around 14 countsmore » per day. A novel approach to the light collection will use a coated hollow light guide cut into the inner copper shielding. Demonstration LSC measurements will show low-energy detection, spectral deconvolution, and alpha/beta discrimination capabilities, from trials with standards of tritium, strontium-90, and actinium-227, respectively. An overview of the system design and expected demonstration measurements will emphasize the potential applications of the ULB-LSC in environmental monitoring for treaty verification, reach-back sample analysis, and facility inspections.« less

  3. Emerging Technologies Program Integration Report. Volume 2. Background, Delphi and Workshop Data. Appendices

    DTIC Science & Technology

    1987-05-04

    FTIILE COP’ AD-A196 840 EMERGING TECHNOLOGIES PROGRAM INTEGRATION REPORT VOLUME II BACKGROUND, DELPHI AND WORKSHOP DATA, APPENDICES . -- PREPARED...Security Classification) Emerging Technologies Program Integration Report Volume II: Background, Delphi and Workshop Data; Appendices (U) 12 PERSONAL...volumes of this integration report assess and synthesize information gathered through a Delphi survey, defense needs prioritization workshops, and

  4. Report: Management Alert - EPA Has Not Initiated Required Background Investigations for Information Systems Contractor Personnel

    EPA Pesticide Factsheets

    Report #17-P-0409, September 27, 2017. Not vetting contractor personnel before granting them network access exposes the EPA to risks. Contractor personnel with potentially questionable backgrounds who access sensitive agency data could cause harm.

  5. Stop the top background of the stop search

    NASA Astrophysics Data System (ADS)

    Bai, Yang; Cheng, Hsin-Chia; Gallicchio, Jason; Gu, Jiayin

    2012-07-01

    The main background for the supersymmetric stop direct production search comes from Standard Model toverline t events. For the single-lepton search channel, we introduce a few kinematic variables to further suppress this background by focusing on its dileptonic and semileptonic topologies. All are defined to have end points in the background, but not signal distributions. They can substantially improve the stop signal significance and mass reach when combined with traditional kinematic variables such as the total missing transverse energy. Among them, our variable M_{{T2}}^W hasthebestoverallperformancebecause it uses all available kinematic information, including the on-shell mass of both W's. We see 20 %-30 % improvement on the discovery significance and estimate that the 8 TeV LHC run with 20 fb-1 of data would be able to reach an exclusion limit of 650-700 GeV for direct stop production, as long as the stop decays dominantly to the top quark and a light stable neutralino. Most of the mass range required for the supersymmetric solution of the naturalness problem in the standard scenario can be covered.

  6. Improved background suppression in 1H MAS NMR using composite pulses

    NASA Astrophysics Data System (ADS)

    Odedra, Smita; Wimperis, Stephen

    2012-08-01

    A well known feature of 1H MAS NMR spectroscopy, particularly of solids where the concentration of 1H nuclei is low, is the presence in the spectrum of a significant broad "background" signal arising from 1H nuclei that are outside the MAS rotor and radiofrequency coil, probably located on the surfaces of the static components of the probehead. A popular method of suppressing this unwanted signal is the "depth pulse" method, consisting of a 90° pulse followed by one or two 180° pulses that are phase cycled according to the "Exorcycle" scheme, which removes signal associated with imperfect 180° pulses. Consequently, only spins in the centre of the radiofrequency coil contribute to the 1H MAS spectrum, while those experiencing a low B1 field outside the coil are suppressed. Although very effective at removing background signal from the spectrum, one drawback with this approach is that significant loss of the desired signal from the sample also occurs. Here we investigate the 1H background suppression problem and, in particular, the use of novel antisymmetric passband composite pulses to replace the simple pulses in a depth pulse experiment. We show that it is possible to improve the intensity of the 1H signals of interest while still maintaining effective background suppression. We expect that these results will be relevant to 1H MAS NMR studies of, for example, nominally perdeuterated biological samples or nominally anhydrous inorganic materials.

  7. Method to determine 226Ra in small sediment samples by ultralow background liquid scintillation.

    PubMed

    Sanchez-Cabeza, Joan-Albert; Kwong, Laval Liong Wee; Betti, Maria

    2010-08-15

    (210)Pb dating of sediment cores is a widely used tool to reconstruct ecosystem evolution and historical pollution during the last century. Although (226)Ra can be determined by gamma spectrometry, this method shows severe limitations which are, among others, sample size requirements and counting times. In this work, we propose a new strategy based on the analysis of (210)Pb through (210)Po in equilibrium by alpha spectrometry, followed by the determination of (226)Ra (base or supported (210)Pb) without any further chemical purification by liquid scintillation and with a higher sample throughput. Although gamma spectrometry might still be required to determine (137)Cs as an independent tracer, the effort can then be focused only on those sections dated around 1963, when maximum activities are expected. In this work, we optimized the counting conditions, calibrated the system for changing quenching, and described the new method to determine (226)Ra in small sediment samples, after (210)Po determination, allowing a more precise determination of excess (210)Pb ((210)Pb(ex)). The method was validated with reference materials IAEA-384, IAEA-385, and IAEA-313.

  8. RenderView: physics-based multi- and hyperspectral rendering using measured background panoramics

    NASA Astrophysics Data System (ADS)

    Talcott, Denise M.; Brown, Wade W.; Thomas, David J.

    2003-09-01

    As part of the survivability engineering process it is necessary to accurately model and visualize the vehicle signatures in multi- or hyperspectral bands of interest. The signature at a given wavelength is a function of the surface optical properties, reflection of the background and, in the thermal region, the emission of thermal radiation. Currently, it is difficult to obtain and utilize background models that are of sufficient fidelity when compared with the vehicle models. In addition, the background models create an additional layer of uncertainty in estimating the vehicles signature. Therefore, to meet exacting rendering requirements we have developed RenderView, which incorporates the full bidirectional reflectance distribution function (BRDF). Instead of using a modeled background we have incorporated a measured calibrated background panoramic image to provide the high fidelity background interaction. Uncertainty in the background signature is reduced to the error in the measurement which is considerably smaller than the uncertainty inherent in a modeled background. RenderView utilizes a number of different descriptions of the BRDF, including the Sandford-Robertson. In addition, it provides complete conservation of energy with off axis sampling. A description of RenderView will be presented along with a methodology developed for collecting background panoramics. Examples of the RenderView output and the background panoramics will be presented along with our approach to handling the solar irradiance problem.

  9. Novel statistical framework to identify differentially expressed genes allowing transcriptomic background differences.

    PubMed

    Ling, Zhi-Qiang; Wang, Yi; Mukaisho, Kenichi; Hattori, Takanori; Tatsuta, Takeshi; Ge, Ming-Hua; Jin, Li; Mao, Wei-Min; Sugihara, Hiroyuki

    2010-06-01

    Tests of differentially expressed genes (DEGs) from microarray experiments are based on the null hypothesis that genes that are irrelevant to the phenotype/stimulus are expressed equally in the target and control samples. However, this strict hypothesis is not always true, as there can be several transcriptomic background differences between target and control samples, including different cell/tissue types, different cell cycle stages and different biological donors. These differences lead to increased false positives, which have little biological/medical significance. In this article, we propose a statistical framework to identify DEGs between target and control samples from expression microarray data allowing transcriptomic background differences between these samples by introducing a modified null hypothesis that the gene expression background difference is normally distributed. We use an iterative procedure to perform robust estimation of the null hypothesis and identify DEGs as outliers. We evaluated our method using our own triplicate microarray experiment, followed by validations with reverse transcription-polymerase chain reaction (RT-PCR) and on the MicroArray Quality Control dataset. The evaluations suggest that our technique (i) results in less false positive and false negative results, as measured by the degree of agreement with RT-PCR of the same samples, (ii) can be applied to different microarray platforms and results in better reproducibility as measured by the degree of DEG identification concordance both intra- and inter-platforms and (iii) can be applied efficiently with only a few microarray replicates. Based on these evaluations, we propose that this method not only identifies more reliable and biologically/medically significant DEG, but also reduces the power-cost tradeoff problem in the microarray field. Source code and binaries freely available for download at http://comonca.org.cn/fdca/resources/softwares/deg.zip.

  10. Background Checks on School Personnel. ERIC Digest Series EA 55.

    ERIC Educational Resources Information Center

    Baas, Alan

    Although it is relatively simple to check on applicants' basic professional competency, ensuring the moral competency of potential school employees is much more difficult. This digest examines major legal issues, district liabilities and responsibilities, suggested guidelines, and information sources involving employee background checks. Of more…

  11. Human Blood Typing: A Forensic Science Approach. Part I: Background.

    ERIC Educational Resources Information Center

    Kobilinsky, Lawrence; Sheehan, Francis X.

    1988-01-01

    In this article, part I of a series, the forensic methods used in "typing" human blood, which as physical evidence is often found in the dried state, are outlined. Background information about individualization, antibody typing, fresh blood, dried blood, and additional systems is provided. (CW)

  12. Background Information for Educators

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2001

    2001-01-01

    Mercury is a naturally occurring and widely used element that can cause health and ecological problems when released to the environment through human activities. Though a national and even international issue, the health and environmental impacts of mercury are best understood when studied at the local level. "Mercury: An Educator's Toolkit"…

  13. How much do I tell thee? Strategies for managing information to parents among American adolescents from Chinese, Mexican, and European backgrounds.

    PubMed

    Tasopoulos-Chan, Marina; Smetana, Judith G; Yau, Jenny P

    2009-06-01

    Strategies for managing information about activities to parents, including partial disclosure, avoidance, lying, and full disclosure, were examined in 479 American adolescents (M = 16.38 years, SD = 0.77) varying in generational status and from Mexican, Chinese, and European backgrounds. Information management strategies for personal, prudential, and overlapping (multifaceted) activities as defined within social domain theory were examined. With age, parental education, and generational status controlled, Chinese American adolescents partially disclosed more to mothers about personal and multifaceted activities than did Mexican American adolescents and more to fathers about personal activities than did European American teens. In contrast, European and Mexican American adolescents fully disclosed more to mothers about personal activities than did Chinese-origin adolescents. Strategies varied by generation among Chinese American youth; second-generation adolescents avoided discussing activities with parents more than did immigrants. Adolescents who fully disclosed about all activities and lied less about multifaceted and personal activities reported stronger endorsement of obligations to assist their families, more trust in parents, and less problem behavior. More depressed mood was associated with more lying about personal activities. Copyright 2009 APA, all rights reserved.

  14. Factors Contributing to Background Television Exposure in Low-Income Mexican-American Preschoolers.

    PubMed

    Thompson, Darcy A; Tschann, Jeanne M

    2016-09-01

    Objective Background television (TV) exposure is harmful to young children, yet few studies have focused on predictors of exposure. This study's objectives were to elucidate demographic, environmental, and behavioral correlates of background TV exposure in low-income Mexican-American preschoolers and to explore caregiver beliefs about the impact of such exposure. Methods A convenience sample of low-income Mexican-American female primary caregivers of preschoolers (3-5 years old, n = 309), recruited in safety-net clinics, were surveyed by phone. Caregivers reported the frequency of their child's exposure to background TV and responded to questions on the home media environment, TV use, and whether they had thought about background TV exposure and its impact on their child. Results Background TV exposure was common; 43 % reported that their child was often, very often, or always exposed to background TV. More hours of TV viewing by the caregiver and greater frequency of TV viewing during meals were associated with an increased frequency of exposure to background TV. Only 49 % of participants had ever thought about the impact of background TV. Believing that background TV is not harmful was associated with higher levels of background TV exposure. Conclusions Findings suggest that background TV exposure is frequent and caregiver awareness of its potential impact is low in low-income Mexican-American families. Beliefs that background TV is not harmful may predict risk of exposure. Potential targets for interventions focused on reducing background TV exposure in this population include increasing caregiver awareness of the potential negative impact of such TV exposure.

  15. Factors contributing to background television exposure in low-income Mexican American preschoolers

    PubMed Central

    Thompson, Darcy A.; Tschann, Jeanne M.

    2016-01-01

    Objective Background television (TV) exposure is harmful to young children, yet few studies have focused on predictors of exposure. This study’s objectives were to elucidate demographic, environmental, and behavioral correlates of background TV exposure in low-income Mexican American preschoolers and to explore caregiver beliefs about the impact of such exposure. Methods A convenience sample of low-income Mexican American female primary caregivers of preschoolers (3–5 years old, n=309), recruited in safety-net clinics, were surveyed by phone. Caregivers reported the frequency of their child’s exposure to background TV and responded to questions on the home media environment, TV use, and whether they had thought about background TV exposure and its impact on their child. Results Background TV exposure was common; 43% reported that their child was often, very often, or always exposed to background TV. More hours of TV viewing by the caregiver and greater frequency of TV viewing during meals were associated with an increased frequency of exposure to background TV. Only 49% of participants had ever thought about the impact of background TV. Believing that background TV is not harmful was associated with higher levels of background TV exposure. Conclusions Findings suggest that background TV exposure is frequent and caregiver awareness of its potential impact is low in low-income Mexican American families. Beliefs that background TV is not harmful may predict risk of exposure. Potential targets for interventions focused on reducing background TV exposure in this population include increasing caregiver awareness of the potential negative impact of such TV exposure. PMID:27007983

  16. Socioeconomic Background, Education, and Labor Force Outcomes: Evidence from a Regional US Sample

    ERIC Educational Resources Information Center

    Caro, Daniel H.; Cortina, Kai S.; Eccles, Jacquelynne S.

    2015-01-01

    This paper examines the long-term association of family socioeconomic status (SES), educational, and labor force outcomes in a regional US longitudinal sample (N = 2264). The results offer insights into the mechanisms underlying the role of family SES in transitions from secondary schooling to early work experiences. It was found that the academic…

  17. 77 FR 55843 - Office of Facilities Management and Program Services; Submission for OMB Review; Background...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... of Facilities Management and Program Services; Submission for OMB Review; Background Investigations... collection of personal data for background investigations for child care workers accessing GSA owned and... assumptions and methodology; ways to enhance the quality, utility, and clarity of the information to be...

  18. Effect of background correction on peak detection and quantification in online comprehensive two-dimensional liquid chromatography using diode array detection.

    PubMed

    Allen, Robert C; John, Mallory G; Rutan, Sarah C; Filgueira, Marcelo R; Carr, Peter W

    2012-09-07

    A singular value decomposition-based background correction (SVD-BC) technique is proposed for the reduction of background contributions in online comprehensive two-dimensional liquid chromatography (LC×LC) data. The SVD-BC technique was compared to simply subtracting a blank chromatogram from a sample chromatogram and to a previously reported background correction technique for one dimensional chromatography, which uses an asymmetric weighted least squares (AWLS) approach. AWLS was the only background correction technique to completely remove the background artifacts from the samples as evaluated by visual inspection. However, the SVD-BC technique greatly reduced or eliminated the background artifacts as well and preserved the peak intensity better than AWLS. The loss in peak intensity by AWLS resulted in lower peak counts at the detection thresholds established using standards samples. However, the SVD-BC technique was found to introduce noise which led to detection of false peaks at the lower detection thresholds. As a result, the AWLS technique gave more precise peak counts than the SVD-BC technique, particularly at the lower detection thresholds. While the AWLS technique resulted in more consistent percent residual standard deviation values, a statistical improvement in peak quantification after background correction was not found regardless of the background correction technique used. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. State background checks for gun purchase and firearm deaths: an exploratory study.

    PubMed

    Sen, Bisakha; Panjamapirom, Anantachai

    2012-10-01

    This study examines the relationship between the types of background-information check required by states prior to firearm purchases, and firearm homicide and suicide deaths. Negative binomial models are used to analyze state-level data for homicides and suicides in the U.S. from 1996 to 2005. Data on types of background information are retrieved from the Surveys of State Procedures Related to Firearm Sales, and the violent death data are from the WISQARS. Several other state level factors were controlled for. More background checks are associated with fewer homicide (IRR:0.93, 95% CI:0.91-0.96) and suicide (IRR:0.98, 95% CI:0.96-1.00) deaths. Firearm homicide deaths are lower when states have checks for restraining orders (IRR:0.87, 95% CI:0.79-0.95) and fugitive status (IRR:0.79, 95% CI:0.72-0.88). Firearm suicide deaths are lower when states have background checks for mental illness (IRR:0.96, 95% CI:0.92-0.99), fugitive status (IRR:0.95, 95% CI:0.90-0.99) and misdemeanors (IRR:0.95, 95% CI:0.92-1.00). It does not appear that reductions in firearm deaths are offset by increases in non-firearm violent deaths. More extensive background checks prior to gun purchase are mostly associated with reductions in firearm homicide and suicide deaths. Several study limitations are acknowledged, and further research is called for to ascertain causality. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. The Conterminous United States Mineral Appraisal Program; background information to accompany folio of geologic, geochemical, geophysical, and mineral resources maps of the Tonopah 1 by 2 degree Quadrangle, Nevada

    USGS Publications Warehouse

    John, David A.; Nash, J.T.; Plouff, Donald; Whitebread, D.H.

    1991-01-01

    The Tonopah 1 ? by 2 ? quadrangle in south-central Nevada was studied by an interdisciplinary research team to appraise its mineral resources. The appraisal is based on geological, geochemical, and geophysical field and laboratory investigations, the results of which are published as a folio of maps, figures, and tables, with accompanying discussions. This circular provides background information on the investigations and integrates the information presented in the folio. The selected bibliography lists references to the geology, geochemistry, geophysics, and mineral deposits of the Tonopah 1 ? by 2 ? quadrangle.

  1. Future Lunar Sampling Missions: Big Returns on Small Samples

    NASA Astrophysics Data System (ADS)

    Shearer, C. K.; Borg, L.

    2002-01-01

    The next sampling missions to the Moon will result in the return of sample mass (100g to 1 kg) substantially smaller than those returned by the Apollo missions (380 kg). Lunar samples to be returned by these missions are vital for: (1) calibrating the late impact history of the inner solar system that can then be extended to other planetary surfaces; (2) deciphering the effects of catastrophic impacts on a planetary body (i.e. Aitken crater); (3) understanding the very late-stage thermal and magmatic evolution of a cooling planet; (4) exploring the interior of a planet; and (5) examining volatile reservoirs and transport on an airless planetary body. Can small lunar samples be used to answer these and other pressing questions concerning important solar system processes? Two potential problems with small, robotically collected samples are placing them in a geologic context and extracting robust planetary information. Although geologic context will always be a potential problem with any planetary sample, new lunar samples can be placed within the context of the important Apollo - Luna collections and the burgeoning planet-scale data sets for the lunar surface and interior. Here we illustrate the usefulness of applying both new or refined analytical approaches in deciphering information locked in small lunar samples.

  2. [Dementia in families with a Turkish migration background. Organization and characteristics of domestic care arrangements].

    PubMed

    Mogar, M; von Kutzleben, M

    2015-07-01

    Until recently public health and health services research has not been concerned with people suffering from dementia with a Turkish migration background as a priority. There is little evidence about the situation of this population; however, it is known that these individuals almost always live with their families and are cared for by their families generally without seeking professional support. The aim of this study was to gain insight into the organization and characteristics of home-based care arrangements for people suffering from dementia with a Turkish migration background from the family carer's perspective. Interviews with seven family carers. The principles of the grounded theory served as a framework for data analysis. Unconditional commitment to caring for a family member with dementia was identified as the main characteristic of care arrangements in families with a Turkish migration background. Dementia is not a factor that has an impact on the decision of families to assume care responsibility for an affected family member and there is a lack of knowledge about dementia in general. There are various inhibiting factors for the utilization of formal services and the family carers in this sample complained that the available services are not culturally sensitive. There seems to be an extensive need for information and counselling regarding care dependency and dementia among the Turkish community. To provide personal-centred care and relief to these families in the future, efforts should be made to adapt the current care system to the specific needs and demands of this population. Cultural sensitivity in general and individual subjective needs of persons with a Turkish migration background affected by dementia should be taken into account.

  3. Background Information on the Very Long Baseline Array

    NASA Astrophysics Data System (ADS)

    A continent-wide radio telescope system offering the greatest resolving power of any astronomical instrument operational today Overview: The National Science Foundation's VLBA is a system of ten identical radio-telescope antennas controlled from a common headquarters and working together as a single instrument. The radio signals received by each individual antenna contribute part of the information used to produce images of celestial objects with hundreds of times more detail than Hubble Space Telescope images. Scientific Areas: The VLBA can contribute to any astronomical research area where quality, high-resolution radio images will advance knowledge of the field. In its first five years of full operation, the VLBA has produced dramatic new information in these areas: * Stars: With the VLBA, astronomers have tracked gas motions in the atmosphere of a star other than the Sun for the first time; made the first maps of the magnetic field of a star other than the Sun; and studied the violent dances of double-star pairs in which one of the pair is a superdense neutron star or a black hole. * Protostars, star formation, and protoplanetary disks: The VLBA has provided scientists with some of the best views yet of very young stars and the complex regions in which they are born. VLBA images have shown outflows of gas from young stars and disks of material orbiting these new stars - material that later may form planetary systems. * Supernovae and Supernova Remnants: The VLBA has directly measured the expansion of a shell of exploded debris from the supernova SN 1993J, in the galaxy M81, some 11 million light-years from Earth. This has allowed scientists to learn new details about the explosion itself and its surroundings as well as calculate the distance to the supernova by using the VLBA data in conjunction with information from optical telescopes. VLBA images have shown regions of shocked gas in supernova remnants. * The Milky Way: Radio waves from extragalactic objects

  4. Thresholding of auditory cortical representation by background noise

    PubMed Central

    Liang, Feixue; Bai, Lin; Tao, Huizhong W.; Zhang, Li I.; Xiao, Zhongju

    2014-01-01

    It is generally thought that background noise can mask auditory information. However, how the noise specifically transforms neuronal auditory processing in a level-dependent manner remains to be carefully determined. Here, with in vivo loose-patch cell-attached recordings in layer 4 of the rat primary auditory cortex (A1), we systematically examined how continuous wideband noise of different levels affected receptive field properties of individual neurons. We found that the background noise, when above a certain critical/effective level, resulted in an elevation of intensity threshold for tone-evoked responses. This increase of threshold was linearly dependent on the noise intensity above the critical level. As such, the tonal receptive field (TRF) of individual neurons was translated upward as an entirety toward high intensities along the intensity domain. This resulted in preserved preferred characteristic frequency (CF) and the overall shape of TRF, but reduced frequency responding range and an enhanced frequency selectivity for the same stimulus intensity. Such translational effects on intensity threshold were observed in both excitatory and fast-spiking inhibitory neurons, as well as in both monotonic and nonmonotonic (intensity-tuned) A1 neurons. Our results suggest that in a noise background, fundamental auditory representations are modulated through a background level-dependent linear shifting along intensity domain, which is equivalent to reducing stimulus intensity. PMID:25426029

  5. Self-referent information processing in individuals with bipolar spectrum disorders

    PubMed Central

    Molz Adams, Ashleigh; Shapero, Benjamin G.; Pendergast, Laura H.; Alloy, Lauren B.; Abramson, Lyn Y.

    2014-01-01

    Background Bipolar spectrum disorders (BSDs) are common and impairing, which has led to an examination of risk factors for their development and maintenance. Historically, research has examined cognitive vulnerabilities to BSDs derived largely from the unipolar depression literature. Specifically, theorists propose that dysfunctional information processing guided by negative self-schemata may be a risk factor for depression. However, few studies have examined whether BSD individuals also show self-referent processing biases. Methods This study examined self-referent information processing differences between 66 individuals with and 58 individuals without a BSD in a young adult sample (age M = 19.65, SD = 1.74; 62% female; 47% Caucasian). Repeated measures multivariate analysis of variance (MANOVA) was conducted to examine multivariate effects of BSD diagnosis on 4 self-referent processing variables (self-referent judgments, response latency, behavioral predictions, and recall) in response to depression-related and nondepression-related stimuli. Results Bipolar individuals endorsed and recalled more negative and fewer positive self-referent adjectives, as well as made more negative and fewer positive behavioral predictions. Many of these information-processing biases were partially, but not fully, mediated by depressive symptoms. Limitations Our sample was not a clinical or treatment-seeking sample, so we cannot generalize our results to clinical BSD samples. No participants had a bipolar I disorder at baseline. Conclusions This study provides further evidence that individuals with BSDs exhibit a negative self-referent information processing bias. This may mean that those with BSDs have selective attention and recall of negative information about themselves, highlighting the need for attention to cognitive biases in therapy. PMID:24074480

  6. Antimicrobial-resistant Klebsiella species isolated from free-range chicken samples in an informal settlement.

    PubMed

    Fielding, Burtram C; Mnabisa, Amanda; Gouws, Pieter A; Morris, Thureyah

    2012-02-29

    Sub-therapeutic doses of antimicrobial agents are administered routinely to poultry to aid growth and to prevent disease, with prolonged exposure often resulting in bacterial resistance. Crossover of antibiotic resistant bacteria from poultry to humans poses a risk to human health. In this study, 17 chicken samples collected from a vendor operating in an informal settlement in the Cape Town Metropolitan area, South Africa were screened for antimicrobial-resistant Gram-negative bacilli using the Kirby Bauer disk diffusion assay. IN TOTAL, SIX ANTIBIOTICS WERE SCREENED: ampicillin, ciprofloxacin, gentamicin, nalidixic acid, tetracycline and trimethoprim. Surprisingly, Klebsiella ozaenae was identified in 96 and K. rhinoscleromatis in 6 (n=102) of the samples tested. Interestingly, ∼40% of the isolated Klebsiella spp. showed multiple resistance to at least three of the six antibiotics tested. Klebsiella ozaenae and K. rhinoscleromatis cause clinical chronic rhinitis and are almost exclusively associated with people living in areas of poor hygiene.

  7. Machismo and Mexican American men: an empirical understanding using a gay sample.

    PubMed

    Estrada, Fernando; Rigali-Oiler, Marybeth; Arciniega, G Miguel; Tracey, Terence J G

    2011-07-01

    Machismo continues to be a defining aspect of Mexican American men that informs a wide array of psychological and behavioral dimensions. Although strides have been made in this area of research, understanding of the role of this construct in the lives of gay men remains incomplete. Our purpose in this study was to gain a deeper understanding of machismo using a sample of Mexican American gay men. This study examined for the first time whether a 2-factor model of machismo previously validated with heterosexual, Mexican American men generalized to a sample of 152 gay men of similar ethnic background. Relations between machismo, sexual risk, and internalized homophobia were also explored. Confirmatory factor analysis supported the 2-factor model with the current sample. Results also indicated machismo as predicting internalized homophobia and as an index of risky sex. Limitations are presented and implications are discussed.

  8. Learning in later life: participation in formal, non-formal and informal activities in a nationally representative Spanish sample.

    PubMed

    Villar, Feliciano; Celdrán, Montserrat

    2013-06-01

    This article examines the participation of Spanish older people in formal, non-formal and informal learning activities and presents a profile of participants in each kind of learning activity. We used data from a nationally representative sample of Spanish people between 60 and 75 years old ( n  = 4,703). The data were extracted from the 2007 Encuesta sobre la Participación de la Población Adulta en Actividades de Aprendizaje (EADA, Survey on Adult Population Involvement in Learning Activities). Overall, only 22.8 % of the sample participated in a learning activity. However, there was wide variation in the participation rates for the different types of activity. Informal activities were far more common than formal ones. Multivariate logistic regression indicated that education level and involvement in social and cultural activities were associated with likelihood of participating, regardless of the type of learning activity. When these variables were taken into account, age did not predict decreasing participation, at least in non-formal and informal activities. Implications for further research, future trends and policies to promote older adult education are discussed.

  9. Gravitational Waves Propagation through the Stochastic Background of Gravitational Waves

    NASA Astrophysics Data System (ADS)

    Frajuca, C.; Bortoli, F. S.; Nakamoto, F. Y.; Santos, G. A.

    2018-02-01

    With the recent claim that gravitational waves were finally detected and with other efforts around the world for GWs detection, its is reasonable to imagine that the relic gravitational wave background could be detected in some time in the future and with such information gather some hints about the origin of the universe. But, it’s also be considered that gravity has self-interaction, with such assumption it’s reasonable to expect that these gravitational wave will interact with the relic or nonrelic GW background by scattering, for example. Such interaction should decrease the distance which such propagating waves could be detected The propagation of gravitational waves (GWs) is analyzed in an asymptotically de Sitter space by the perturbation expansion around Minkowski space using a scalar component. Using the case of de Sitter inflationary phase scenario, the perturbation propagates through a FRW background. The GW, using the actual value for the Hubble scale (Ho), has a damping factor with a very small valor for the size of the observational universe; the stochastic relic GW background is given by a dimensionless function of the frequency. In this work we analyze this same damping including the gravitational wave background due to astrophysical sources such background is 3 orders of magnitude bigger in some frequencies and produces a higher damping factor.

  10. Background Stress Inventory: Developing a Measure of Understudied Stress.

    PubMed

    Terrill, Alexandra L; Gjerde, Jill M; Garofalo, John P

    2015-10-01

    Background stress is an understudied source of stress that involves both ambient stress and daily hassles upon which new stressors are superimposed. To date, an accurate measure of the background stress construct has not been available. We developed the Background Stress Inventory, a 25-item self-report measure that asks respondents to indicate how distressed they have felt over the past month and the majority of the past year across five domains: financial, occupation, environment, health and social. Seven hundred seventy-two participants completed the paper-and-pencil measure; the sample was randomly split into two separate subsamples for analyses. Exploratory factor analysis suggested five factors corresponding to these domains, and confirmatory factor analysis showed acceptable global fit (X(2)(255) = 456.47, comparative fit index = 0.94, root mean square error of approximation = 0.045). Cronbach's alpha (0.89) indicated good internal reliability. Construct validity analyses showed significant positive relationships with measures of perceived stressfulness (r = 0.62) and daily hassles (0.41), p's < 0.01. Depressive symptoms (0.62) and basal blood pressure (0.21) were both significantly associated with background stress, p's < 0.01. The importance of the proposed measure is reflected in the limited research base on the impact of background stress. Systematic investigation of this measure will provide insight into this understudied form of chronic stress and its potential influence on both psychological and physical endpoints. Copyright © 2013 John Wiley & Sons, Ltd.

  11. Increasing Educational Efficiency Through Technology (Commission Discussion and Background Materials).

    ERIC Educational Resources Information Center

    Indiana State Commission for Higher Education, Indianapolis.

    A program schedule and background information for Indiana Commission for Higher Education-sponsored discussion of the use of educational technology to increase educational effeciency are presented. The four major topics of discussion to illustrate the uses and advantages/disadvantages of audio, video, and computing technologies are as follows:…

  12. Background sources at PEP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lynch, H.; Schwitters, R.F.; Toner, W.T.

    Important sources of background for PEP experiments are studied. Background particles originate from high-energy electrons and positrons which have been lost from stable orbits, ..gamma..-rays emitted by the primary beams through bremsstrahlung in the residual gas, and synchrotron radiation x-rays. The effect of these processes on the beam lifetime are calculated and estimates of background rates at the interaction region are given. Recommendations for the PEP design, aimed at minimizing background are presented. 7 figs., 4 tabs.

  13. Implications of sampling design and sample size for national carbon accounting systems

    Treesearch

    Michael Köhl; Andrew Lister; Charles T. Scott; Thomas Baldauf; Daniel Plugge

    2011-01-01

    Countries willing to adopt a REDD regime need to establish a national Measurement, Reporting and Verification (MRV) system that provides information on forest carbon stocks and carbon stock changes. Due to the extensive areas covered by forests the information is generally obtained by sample based surveys. Most operational sampling approaches utilize a combination of...

  14. The Effect of Background Noise on Intelligibility of Dysphonic Speech

    ERIC Educational Resources Information Center

    Ishikawa, Keiko; Boyce, Suzanne; Kelchner, Lisa; Powell, Maria Golla; Schieve, Heidi; de Alarcon, Alessandro; Khosla, Sid

    2017-01-01

    Purpose: The aim of this study is to determine the effect of background noise on the intelligibility of dysphonic speech and to examine the relationship between intelligibility in noise and an acoustic measure of dysphonia--cepstral peak prominence (CPP). Method: A study of speech perception was conducted using speech samples from 6 adult speakers…

  15. Improved background suppression in ¹H MAS NMR using composite pulses.

    PubMed

    Odedra, Smita; Wimperis, Stephen

    2012-08-01

    A well known feature of ¹H MAS NMR spectroscopy, particularly of solids where the concentration of ¹H nuclei is low, is the presence in the spectrum of a significant broad "background" signal arising from ¹H nuclei that are outside the MAS rotor and radiofrequency coil, probably located on the surfaces of the static components of the probehead. A popular method of suppressing this unwanted signal is the "depth pulse" method, consisting of a 90° pulse followed by one or two 180° pulses that are phase cycled according to the "Exorcycle" scheme, which removes signal associated with imperfect 180° pulses. Consequently, only spins in the centre of the radiofrequency coil contribute to the ¹H MAS spectrum, while those experiencing a low B₁ field outside the coil are suppressed. Although very effective at removing background signal from the spectrum, one drawback with this approach is that significant loss of the desired signal from the sample also occurs. Here we investigate the ¹H background suppression problem and, in particular, the use of novel antisymmetric passband composite pulses to replace the simple pulses in a depth pulse experiment. We show that it is possible to improve the intensity of the ¹H signals of interest while still maintaining effective background suppression. We expect that these results will be relevant to ¹H MAS NMR studies of, for example, nominally perdeuterated biological samples or nominally anhydrous inorganic materials. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. 21 CFR 71.4 - Samples; additional information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... samples of the color additive, articles used as components thereof, or of the food, drug, or cosmetic in... additive, or articles used as components thereof, or of the food, drug, or cosmetic in which the color...

  17. 21 CFR 71.4 - Samples; additional information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... samples of the color additive, articles used as components thereof, or of the food, drug, or cosmetic in... additive, or articles used as components thereof, or of the food, drug, or cosmetic in which the color...

  18. 21 CFR 71.4 - Samples; additional information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... samples of the color additive, articles used as components thereof, or of the food, drug, or cosmetic in... additive, or articles used as components thereof, or of the food, drug, or cosmetic in which the color...

  19. 21 CFR 71.4 - Samples; additional information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... samples of the color additive, articles used as components thereof, or of the food, drug, or cosmetic in... additive, or articles used as components thereof, or of the food, drug, or cosmetic in which the color...

  20. 21 CFR 71.4 - Samples; additional information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... samples of the color additive, articles used as components thereof, or of the food, drug, or cosmetic in... additive, or articles used as components thereof, or of the food, drug, or cosmetic in which the color...

  1. Community Information Systems.

    ERIC Educational Resources Information Center

    Freeman, Andrew

    Information is provided on technological and social trends as background for a workshop designed to heighten the consciousness of workers in community information systems. Initially, the basic terminology is considered in its implications for an integrated perspective of community information systems, with particular attention given to the meaning…

  2. Prevalence and Mental Health Outcomes of Homicide Survivors in a Representative US Sample of Adolescents: Data from the 2005 National Survey of Adolescents

    ERIC Educational Resources Information Center

    Rheingold, Alyssa A.; Zinzow, Heidi; Hawkins, Alesia; Saunders, Benjamin E.; Kilpatrick, Dean G.

    2012-01-01

    Background: Each homicide leaves behind several friends and family members, or homicide survivors. However, limited information is available on the impact of homicide on adolescent survivors. The purpose of the current study was to identify the prevalence of homicide survivorship and to determine mental health outcomes within a sample of US…

  3. What’s Important to the Patient?: Informational Needs of Patients Making Decisions about Hepatitis C Treatment

    PubMed Central

    Evon, Donna M.; Golin, Carol E.; Stoica, Teodora; Jones, Rachel; Willis, Sarah; Galanko, Joseph; Fried, Michael W.

    2017-01-01

    Background & Objectives Multiple treatment options with direct-acting antivirals (DAAs) are now available for hepatitis C virus (HCV). Study aims were to understand (1) The informational topics patients want to have to make informed treatment decisions; (2) The importance patients place on each topic; and (3) The topics patients prioritize as most important. Methods Mixed methods study utilizing two samples recruited from an academic liver center. Participants were not currently on treatment. Sample I (n=45) free-listed all informational topics deemed important to decision-making. Raw responses were coded into several broad and subcategories. Sample II (n=38) rated the importance of the subcategories from Sample I and ranked their highest priorities on two surveys, one containing topics for which sufficient research existed to inform patients (“static”), and the other containing topics that would require additional research. Results The topics listed by Sample I fell into 6 broad categories with 17 total subcategories. The most oft-cited informational topics were harms of treatment (100%), treatment benefits (62%) and treatment regimen details (84%). Sample II rated 16 of 17 subcategories as “pretty important’ or “extremely important.” Sample II prioritized (1) viral cure, (2) long-term survival, and (3) side effects on the survey of topics requiring additional research, and (1) liver disease, (2) lifestyle changes, and (3) medication details on the second survey of the most important static topics patients needed. Conclusions Patients weighed several informational topics to make an informed decision about HCV treatment. These findings lay the groundwork for future patient-centered outcomes research in HCV and patient-provider communication to enhance patients’ informed decision-making regarding DAA treatment options. PMID:27882509

  4. Sampling and assessment accuracy in mate choice: a random-walk model of information processing in mating decision.

    PubMed

    Castellano, Sergio; Cermelli, Paolo

    2011-04-07

    Mate choice depends on mating preferences and on the manner in which mate-quality information is acquired and used to make decisions. We present a model that describes how these two components of mating decision interact with each other during a comparative evaluation of prospective mates. The model, with its well-explored precedents in psychology and neurophysiology, assumes that decisions are made by the integration over time of noisy information until a stopping-rule criterion is reached. Due to this informational approach, the model builds a coherent theoretical framework for developing an integrated view of functions and mechanisms of mating decisions. From a functional point of view, the model allows us to investigate speed-accuracy tradeoffs in mating decision at both population and individual levels. It shows that, under strong time constraints, decision makers are expected to make fast and frugal decisions and to optimally trade off population-sampling accuracy (i.e. the number of sampled males) against individual-assessment accuracy (i.e. the time spent for evaluating each mate). From the proximate-mechanism point of view, the model makes testable predictions on the interactions of mating preferences and choosiness in different contexts and it might be of compelling empirical utility for a context-independent description of mating preference strength. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. Real-time assessment of hybridization between wolves and dogs: combining noninvasive samples with ancestry informative markers.

    PubMed

    Godinho, Raquel; López-Bao, José Vicente; Castro, Diana; Llaneza, Luís; Lopes, Susana; Silva, Pedro; Ferrand, Nuno

    2015-03-01

    Wolves and dogs provide a paradigmatic example of the ecological and conservation implications of hybridization events between wild and domesticated forms. However, our understanding of such implications has been traditionally hampered by both high genetic similarity and the difficulties in obtaining tissue samples (TS), which limit our ability to assess ongoing hybridization events. To assess the occurrence and extension of hybridization in a pack of wolf-dog hybrids in northwestern Iberia, we compared the power of 52 nuclear markers implemented on TS with a subset of 13 ancestry informative markers (AIMs) typed in noninvasive samples (NIS). We demonstrate that the 13 AIMs are as accurate as the 52 markers that were chosen without regard to the power to differentiate between wolves and dogs, also having the advantage of being rapidly screened on NIS. The efficiency of AIMs significantly outperformed ten random sets of similar size and an additional commercial set of 18 markers. Bayesian clustering analysis implemented on AIMs and NIS identified nine hybrids, two wolves and two dogs. Four hybrids were unambiguously assigned to F1xWolf backcrosses. Our approach (AIMs + NIS) overcomes previous difficulties related to sample availability and informative power of markers, allowing a quick identification of wolf-dog hybrids in the first phases of hybridization episodes. This provides managers with a reliable tool to evaluate hybridization and estimate the success of their actions. This approach may be easily adapted for other pairs of wild/domesticated species, thus improving our understanding of the introgression of domestication genes into natural populations. © 2014 John Wiley & Sons Ltd.

  6. Can muon-induced backgrounds explain the DAMA data?

    NASA Astrophysics Data System (ADS)

    Klinger, Joel; Kudryavtsev, Vitaly A.

    2016-05-01

    We present an accurate simulation of the muon-induced background in the DAMA/LIBRA experiment. Muon sampling underground has been performed using the MUSIC/MUSUN codes and subsequent interactions in the rock around the DAMA/LIBRA detector cavern and the experimental setup including shielding, have been simulated with GEANT4.9.6. In total we simulate the equivalent of 20 years of muon data. We have calculated the total muon-induced neutron flux in the DAMA/LIBRA detector cavern as Φμ n = 1.0 × 10-9 cm-2s-1, which is consistent with other simulations. After selecting events which satisfy the DAMA/LIBRA signal criteria, our simulation predicts 3.49 × 10-5 cpd/kg/keV which accounts for less than 0.3% of the DAMA/LIBRA modulation amplitude. We conclude from our work that muon-induced backgrounds are unable to contribute to the observed signal modulation.

  7. Investigating the relationship between information literacy and academic performance among students

    PubMed Central

    Soleymani, Mohammad Reza

    2014-01-01

    Background: Nowadays, no student can ever pursue the ends of his studies unless he makes use of his information literacy skills. To become lifelong learners, they do need these skills. Information literacy is a set of information needed for searching, retrieval, evaluating, and making best use of information. This study uncovers the relationship between information literacy and academic performance among students at Isfahan University of Medical Sciences. Materials and Methods: This is a practical study using a survey method. All MA students in Isfahan University of Medical Sciences make the statistical population for this study, according to the sample size determined by using Cochran formula 265 samples that were selected by stratified random sampling. Data collection was through information literacy questionnaires designed by Davarpanah and Siamak, verified by Library and Information Sciences experts; and finally, gave a Cronbach's alpha of 0.83. To determine academic performance, the average scores of the students in previous semesters were considered. Results: The information literacy of all other students was significantly higher than medium except for students at Nursing and Nutrition faculties. The students of Management and Information Sciences faculty had the highest level of information literacy and students of nutrition faculty were attributed with the least level. There was no significant difference between male and female students’ information literacy. We also found out that there was a significant positive relationship between information literacy and students’ academic performance in Isfahan University of Medical Sciences. Conclusion: Information literacy is one of the most important factors that leads to educational success. As there is a significant positive relationship between information literacy and students’ academic performance, we should necessarily provide them with relative skills dealing with information literacy to improve their

  8. Cephalopod dynamic camouflage: bridging the continuum between background matching and disruptive coloration

    PubMed Central

    Hanlon, R.T.; Chiao, C.-C.; Mäthger, L.M.; Barbosa, A.; Buresch, K.C.; Chubb, C.

    2008-01-01

    Individual cuttlefish, octopus and squid have the versatile capability to use body patterns for background matching and disruptive coloration. We define—qualitatively and quantitatively—the chief characteristics of the three major body pattern types used for camouflage by cephalopods: uniform and mottle patterns for background matching, and disruptive patterns that primarily enhance disruptiveness but aid background matching as well. There is great variation within each of the three body pattern types, but by defining their chief characteristics we lay the groundwork to test camouflage concepts by correlating background statistics with those of the body pattern. We describe at least three ways in which background matching can be achieved in cephalopods. Disruptive patterns in cuttlefish possess all four of the basic components of ‘disruptiveness’, supporting Cott's hypotheses, and we provide field examples of disruptive coloration in which the body pattern contrast exceeds that of the immediate surrounds. Based upon laboratory testing as well as thousands of images of camouflaged cephalopods in the field (a sample is provided on a web archive), we note that size, contrast and edges of background objects are key visual cues that guide cephalopod camouflage patterning. Mottle and disruptive patterns are frequently mixed, suggesting that background matching and disruptive mechanisms are often used in the same pattern. PMID:19008200

  9. Modelling of celestial backgrounds

    NASA Astrophysics Data System (ADS)

    Hickman, Duncan L.; Smith, Moira I.; Lim, Jae-Wan; Jeon, Yun-Ho

    2018-05-01

    For applications where a sensor's image includes the celestial background, stars and Solar System Bodies compromise the ability of the sensor system to correctly classify a target. Such false targets are particularly significant for the detection of weak target signatures which only have a small relative angular motion. The detection of celestial features is well established in the visible spectral band. However, given the increasing sensitivity and low noise afforded by emergent infrared focal plane array technology together with larger and more efficient optics, the signatures of celestial features can also impact performance at infrared wavelengths. A methodology has been developed which allows the rapid generation of celestial signatures in any required spectral band using star data from star catalogues and other open-source information. Within this paper, the radiometric calculations are presented to determine the irradiance values of stars and planets in any spectral band.

  10. Rasch fit statistics and sample size considerations for polytomous data

    PubMed Central

    Smith, Adam B; Rush, Robert; Fallowfield, Lesley J; Velikova, Galina; Sharpe, Michael

    2008-01-01

    Background Previous research on educational data has demonstrated that Rasch fit statistics (mean squares and t-statistics) are highly susceptible to sample size variation for dichotomously scored rating data, although little is known about this relationship for polytomous data. These statistics help inform researchers about how well items fit to a unidimensional latent trait, and are an important adjunct to modern psychometrics. Given the increasing use of Rasch models in health research the purpose of this study was therefore to explore the relationship between fit statistics and sample size for polytomous data. Methods Data were collated from a heterogeneous sample of cancer patients (n = 4072) who had completed both the Patient Health Questionnaire – 9 and the Hospital Anxiety and Depression Scale. Ten samples were drawn with replacement for each of eight sample sizes (n = 25 to n = 3200). The Rating and Partial Credit Models were applied and the mean square and t-fit statistics (infit/outfit) derived for each model. Results The results demonstrated that t-statistics were highly sensitive to sample size, whereas mean square statistics remained relatively stable for polytomous data. Conclusion It was concluded that mean square statistics were relatively independent of sample size for polytomous data and that misfit to the model could be identified using published recommended ranges. PMID:18510722

  11. Genetic effects on information processing speed are moderated by age--converging results from three samples.

    PubMed

    Ising, M; Mather, K A; Zimmermann, P; Brückl, T; Höhne, N; Heck, A; Schenk, L A; Rujescu, D; Armstrong, N J; Sachdev, P S; Reppermund, S

    2014-06-01

    Information processing is a cognitive trait forming the basis of complex abilities like executive function. The Trail Making Test (TMT) is a well-established test of information processing with moderate to high heritability. Age of the individual also plays an important role. A number of genetic association studies with the TMT have been performed, which, however, did not consider age as a moderating factor. We report the results of genome-wide association studies (GWASs) on age-independent and age-dependent TMT performance in two population-representative community samples (Munich Antidepressant Response Signature, MARS: N1 = 540; Ludwig Maximilians University, LMU: N2 = 350). Age-dependent genome-wide findings were then evaluated in a third sample of healthy elderly subjects (Sydney Memory and Ageing Study, Sydney MAS: N3 = 448). While a meta-analysis on the GWAS findings did not reveal age-independent TMT associations withstanding correction for multiple testing, we found a genome-wide significant age-moderated effect between variants in the DSG1 gene region and TMT-A performance predominantly reflecting visual processing speed (rs2199301, P(meta-analysis) = 1.3 × 10(-7)). The direction of the interaction suggests for the minor allele a beneficial effect in younger adults turning into a detrimental effect in older adults. The detrimental effect of the missense single nucleotide polymorphism rs1426310 within the same DSG1 gene region could be replicated in Sydney MAS participants aged 70-79, but not in those aged 80 years and older, presumably a result of survivor bias. Our findings demonstrate opposing effects of DSG1 variants on information processing speed depending on age, which might be related to the complex processes that DSG1 is involved with, including cell adhesion and apoptosis. © 2014 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  12. Ultra-high sensitivity moment magnetometry of geological samples using magnetic microscopy

    NASA Astrophysics Data System (ADS)

    Lima, Eduardo A.; Weiss, Benjamin P.

    2016-09-01

    Useful paleomagnetic information is expected to be recorded by samples with moments up to three orders of magnitude below the detection limit of standard superconducting rock magnetometers. Such samples are now detectable using recently developed magnetic microscopes, which map the magnetic fields above room-temperature samples with unprecedented spatial resolutions and field sensitivities. However, realizing this potential requires the development of techniques for retrieving sample moments from magnetic microscopy data. With this goal, we developed a technique for uniquely obtaining the net magnetic moment of geological samples from magnetic microscopy maps of unresolved or nearly unresolved magnetization. This technique is particularly powerful for analyzing small, weakly magnetized samples such as meteoritic chondrules and terrestrial silicate crystals like zircons. We validated this technique by applying it to field maps generated from synthetic sources and also to field maps measured using a superconducting quantum interference device (SQUID) microscope above geological samples with moments down to 10-15 Am2. For the most magnetic rock samples, the net moments estimated from the SQUID microscope data are within error of independent moment measurements acquired using lower sensitivity standard rock magnetometers. In addition to its superior moment sensitivity, SQUID microscope net moment magnetometry also enables the identification and isolation of magnetic contamination and background sources, which is critical for improving accuracy in paleomagnetic studies of weakly magnetic samples.

  13. Expected Backgrounds of the BetaCage, an Ultra-sensitive Screener for Surface Contamination

    NASA Astrophysics Data System (ADS)

    Wang, Boqian; Bunker, Raymond; Schnee, Richard; Bowles, Michael; Kos, Marek; Ahmed, Zeeshan; Golwala, Sunil; Nelson, Robert; Grant, Darren

    2013-04-01

    Material screening for low-energy betas and alphas is necessary for rare-event-search experiments, such as dark matter and neutrinoless double-beta decay searches where surface radiocontamination has become a significant background. The BetaCage, a gaseous neon time-projection chamber, has been proposed as a screener for emitters of low-energy betas and alphas to which existing screening facilities are insufficiently sensitive. The expected sensitivity is 0.1 betas / (keV m^2 day) and 0.1 alphas / (m^2 day). Expected backgrounds are dominated by Compton scattering of external photons in the sample to be screened; radioassays and simulations indicate backgrounds from detector materials and radon daughters should be subdominant. We will report on details of the background simulations and the detector design that allows discrimination to reach these sensitivity levels.

  14. The background is remapped across saccades.

    PubMed

    Cha, Oakyoon; Chong, Sang Chul

    2014-02-01

    Physiological studies have found that neurons prepare for impending eye movements, showing anticipatory responses to stimuli presented at the location of the post-saccadic receptive fields (RFs) (Wurtz in Vis Res 48:2070-2089, 2008). These studies proposed that visual neurons with shifting RFs prepared for the stimuli they would process after an impending saccade. Additionally, psychophysical studies have shown behavioral consequences of those anticipatory responses, including the transfer of aftereffects (Melcher in Nat Neurosci 10:903-907, 2007) and the remapping of attention (Rolfs et al. in Nat Neurosci 14:252-258, 2011). As the physiological studies proposed, the shifting RF mechanism explains the transfer of aftereffects. Recently, a new mechanism based on activation transfer via a saliency map was proposed, which accounted for the remapping of attention (Cavanagh et al. in Trends Cogn Sci 14:147-153, 2010). We hypothesized that there would be different aspects of the remapping corresponding to these different neural mechanisms. This study found that the information in the background was remapped to a similar extent as the figure, provided that the visual context remained stable. We manipulated the status of the figure and the ground in the saliency map and showed that the manipulation modulated the remapping of the figure and the ground in different ways. These results suggest that the visual system has an ability to remap the background as well as the figure, but lacks the ability to modulate the remapping of the background based on the visual context, and that different neural mechanisms might work together to maintain visual stability across saccades.

  15. Testing measurement invariance of the patient-reported outcomes measurement information system pain behaviors score between the US general population sample and a sample of individuals with chronic pain.

    PubMed

    Chung, Hyewon; Kim, Jiseon; Cook, Karon F; Askew, Robert L; Revicki, Dennis A; Amtmann, Dagmar

    2014-02-01

    In order to test the difference between group means, the construct measured must have the same meaning for all groups under investigation. This study examined the measurement invariance of responses to the patient-reported outcomes measurement information system (PROMIS) pain behavior (PB) item bank in two samples: the PROMIS calibration sample (Wave 1, N = 426) and a sample recruited from the American Chronic Pain Association (ACPA, N = 750). The ACPA data were collected to increase the number of participants with higher levels of pain. Multi-group confirmatory factor analysis (MG-CFA) and two item response theory (IRT)-based differential item functioning (DIF) approaches were employed to evaluate the existence of measurement invariance. MG-CFA results supported metric invariance of the PROMIS-PB, indicating unstandardized factor loadings with equal across samples. DIF analyses revealed that impact of 6 DIF items was negligible. Based on the results of both MG-CFA and IRT-based DIF approaches, we recommend retaining the original parameter estimates obtained from the combined samples based on the results of MG-CFA.

  16. Cadmium background concentrations to establish reference quality values for soils of São Paulo State, Brazil.

    PubMed

    de Oliveira, Vinicius Henrique; de Abreu, Cleide Aparecida; Coelho, Ricardo Marques; Melo, Leônidas Carrijo Azevedo

    2014-03-01

    Proper assessment of soil cadmium (Cd) concentrations is essential to establish legislative limits. The present study aimed to assess background Cd concentrations in soils from the state of São Paulo, Brazil, and to correlate such concentrations with several soil attributes. The topsoil samples (n = 191) were assessed for total Cd contents and for other metals using the USEPA 3051A method. The background concentration was determined according to the third quartile (75th). Principal component analysis, Spearman correlation, and multiple regressions between Cd contents and other soil attributes (pH, cation exchange capacity (CEC), clay content, sum of bases, organic matter, and total Fe, Al, Zn, and Pb levels) were performed. The mean Cd concentration of all 191 samples was 0.4 mg kg(-1), and the background concentration was 0.5 mg kg(-1). After the samples were grouped by parent material (rock origin) and soil type, the background Cd content varied, i.e., soils from igneous, metamorphic, and sedimentary rocks harbored 1.5, 0.4, and 0.2 mg kg(-1) of Cd, respectively. The background Cd content in Oxisols (0.8 mg kg(-1)) was higher than in Ultisols (0.3 mg kg(-1)). Multiple regression demonstrated that Fe was primarily attributed to the natural Cd contents in the soils (R (2) = 0.79). Instead of a single Cd background concentration value representing all São Paulo soils, we propose that the concentrations should be specific for at least Oxisols and Ultisols, which are the primary soil types.

  17. Study of the dislocation contribution to the internal friction background of gold

    NASA Astrophysics Data System (ADS)

    Baur, J.; Benoit, W.

    1987-04-01

    The dislocation contribution to the internal friction (IF) background is studied in annealed gold samples containing various dilute concentrations of platinum impurities. The measurements are performed in the kHz frequency range in order to determine the loss mechanism responsible for the high IF background observed at these low frequencies. To this end, the IF background was systematically measured as a function of frequency, vibration amplitude, temperature, and impurity concentration. The experimental results show that the high dislocation contribution observed in annealed samples is strain-amplitude independent for amplitudes in the range 10-7 to 2×10-6, but rapidly decreases for amplitudes smaller than 10-7. In particular, the dislocation contribution tends to zero when the strain amplitude tends to zero. Furthermore, this contribution is frequency independent. These observations demonstrate that the dislocation contribution cannot be explained by relaxations. In particular, this contribution cannot be attributed to a viscous damping of the dislocation motion. On the contrary, the experiments show that the IF background due to dislocations must be explained by hysteretic and athermal motions of dislocations interacting with point defects. However, these hysteretic motions are not due to breakaway of dislocations from pinning points distributed along their length. The experimental results can be explained by the presence of point defects close to the dislocations, but not on them. The mechanical energy loss is attributed to hysteretic motions of dislocations between potential minima created by point defects.

  18. X-ray absorption spectroscopy to determine originating depth of electrons that form an inelastic background of Auger electron spectrum

    NASA Astrophysics Data System (ADS)

    Isomura, Noritake; Cui, Yi-Tao; Murai, Takaaki; Oji, Hiroshi; Kimoto, Yasuji

    2017-07-01

    In Auger electron spectroscopy (AES), the spectral background is mainly due to inelastic scattering of Auger electrons that lose their kinetic energy in a sample bulk. To investigate the spectral components within this background for SiO2(19.3 nm)/Si(100) with known layer thickness, X-ray absorption spectroscopy (XAS) was used in the partial-electron-yield (PEY) mode at several electron kinetic energies to probe the background of the Si KLL Auger peak. The Si K-edge PEY-XAS spectra constituted of both Si and SiO2 components at each kinetic energy, and their component fractions were approximately the same as those derived from the simulated AES background for the same sample structure. The contributions of Auger electrons originating from layers at different depths to the inelastic background could thus be identified experimentally.

  19. Coffee aroma: Chemometric comparison of the chemical information provided by three different samplings combined with GC-MS to describe the sensory properties in cup.

    PubMed

    Bressanello, Davide; Liberto, Erica; Cordero, Chiara; Rubiolo, Patrizia; Pellegrino, Gloria; Ruosi, Manuela R; Bicchi, Carlo

    2017-01-01

    This study is part of a wider project aiming to correlate the chemical composition of the coffee volatile fraction to its sensory properties with the end-goal of developing an instrumental analysis approach complementary to human sensory profiling. The proposed investigation strategy compares the chemical information concerning coffee aroma and flavor obtained with HS-SPME of the ground coffee and in-solution SBSE/SPME sampling combined with GC-MS to evaluate their compatibility with the cupping evaluation for quality control purposes. Roasted coffee samples with specific sensory properties were analyzed. The chemical results obtained by the three samplings were compared through multivariate analysis, and related to the samples' sensory attributes. Despite the differences between the three sampling approaches, data processing showed that the three methods provide the same kind of chemical information useful for sample discrimination, and that they could be used interchangeably to sample the coffee aroma and flavor. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Precise predictions for V+jets dark matter backgrounds

    NASA Astrophysics Data System (ADS)

    Lindert, J. M.; Pozzorini, S.; Boughezal, R.; Campbell, J. M.; Denner, A.; Dittmaier, S.; Gehrmann-De Ridder, A.; Gehrmann, T.; Glover, N.; Huss, A.; Kallweit, S.; Maierhöfer, P.; Mangano, M. L.; Morgan, T. A.; Mück, A.; Petriello, F.; Salam, G. P.; Schönherr, M.; Williams, C.

    2017-12-01

    High-energy jets recoiling against missing transverse energy (MET) are powerful probes of dark matter at the LHC. Searches based on large MET signatures require a precise control of the Z(ν {\\bar{ν }})+ jet background in the signal region. This can be achieved by taking accurate data in control regions dominated by Z(ℓ ^+ℓ ^-)+ jet, W(ℓ ν )+ jet and γ + jet production, and extrapolating to the Z(ν {\\bar{ν }})+ jet background by means of precise theoretical predictions. In this context, recent advances in perturbative calculations open the door to significant sensitivity improvements in dark matter searches. In this spirit, we present a combination of state-of-the-art calculations for all relevant V+ jets processes, including throughout NNLO QCD corrections and NLO electroweak corrections supplemented by Sudakov logarithms at two loops. Predictions at parton level are provided together with detailed recommendations for their usage in experimental analyses based on the reweighting of Monte Carlo samples. Particular attention is devoted to the estimate of theoretical uncertainties in the framework of dark matter searches, where subtle aspects such as correlations across different V+ jet processes play a key role. The anticipated theoretical uncertainty in the Z(ν {\\bar{ν }})+ jet background is at the few percent level up to the TeV range.

  1. Impact of Sociocultural Background and Assessment Data Upon School Psychologists' Decisions.

    ERIC Educational Resources Information Center

    Huebner, E. Scott; Cummings, Jack A.

    1985-01-01

    Psychologists (N=56) participated in an adapted version of Algozzine and Ysseldyke's (1981) diagnostic simulation to investigate the effects of sociocultural background (rural vs. suburban) and assessment data (normal vs. learning disabled) on educational decisions. Findings suggest school psychologists utilize multiple sources of information but…

  2. Simultaneous measurement of tritium and radiocarbon by ultra-low-background proportional counting.

    PubMed

    Mace, Emily; Aalseth, Craig; Alexander, Tom; Back, Henning; Day, Anthony; Hoppe, Eric; Keillor, Martin; Moran, Jim; Overman, Cory; Panisko, Mark; Seifert, Allen

    2017-08-01

    Use of ultra-low-background capabilities at Pacific Northwest National Laboratory provide enhanced sensitivity for measurement of low-activity sources of tritium and radiocarbon using proportional counters. Tritium levels are nearly back to pre-nuclear test backgrounds (~2-8 TU in rainwater), which can complicate their dual measurement with radiocarbon due to overlap in the beta decay spectra. We present results of single-isotope proportional counter measurements used to analyze a dual-isotope methane sample synthesized from ~120mg of H 2 O and present sensitivity results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Simultaneous measurement of tritium and radiocarbon by ultra-low-background proportional counting

    DOE PAGES

    Mace, Emily; Aalseth, Craig; Alexander, Tom; ...

    2016-12-21

    Use of ultra-low-background capabilities at Pacific Northwest National Laboratory provide enhanced sensitivity for measurement of low-activity sources of tritium and radiocarbon using proportional counters. Tritium levels are nearly back to pre-nuclear test backgrounds (~2-8 TU in rainwater), which can complicate their dual measurement with radiocarbon due to overlap in the beta decay spectra. In this paper, we present results of single-isotope proportional counter measurements used to analyze a dual-isotope methane sample synthesized from ~120 mg of H 2O and present sensitivity results.

  4. How the Hawking radiation affect quantum Fisher information of Dirac particles in the background of a Schwarzschild black hole

    NASA Astrophysics Data System (ADS)

    Huang, ChunYu; Ma, Wen-chao; Wang, Dong; Ye, Liu

    2018-01-01

    In this work, the effect of Hawking radiation on the quantum Fisher information (QFI) of Dirac particles is investigated in the background of a Schwarzschild black hole. Interestingly, it has been verified that the QFI with respect to the weight parameter θ of a target state is always independent of the Hawking temperature T. This implies that if we encode the information on the weight parameter, then we can affirm that the corresponding accuracy of the parameter estimation will be immune to the Hawking effect. Besides, it reveals that the QFI with respect to the phase parameter φ exhibits a decay behavior with the increase in the Hawking temperature T and converges to a nonzero value in the limit of infinite Hawking temperature T. Remarkably, it turns out that the function F_φ on θ =π \\big /4 symmetry was broken by the influence of the Hawking radiation. Finally, we generalize the case of a three-qubit system to a case of a N-qubit system, i.e., |ψ > _{1,2,3,\\ldots ,N} =(cos θ | 0 > ^{⊗ N}+sin θ e^{iφ }| 1 > ^{⊗ N}) and obtain an interesting result: the number of particles in the initial state does not affect the QFI F_θ , nor the QFI F_φ . However, with the increasing number of particles located near the event horizon, F_φ will be affected by Hawking radiation to a large extent, while F_θ is still free from disturbance resulting from the Hawking effects.

  5. Quantitative chemical imaging with background-free multiplex coherent anti-Stokes Raman scattering by dual-soliton Stokes pulses

    PubMed Central

    Chen, Kun; Wu, Tao; Wei, Haoyun; Zhou, Tian; Li, Yan

    2016-01-01

    Coherent anti-Stokes Raman microscopy (CARS) is a quantitative, chemically specific, and label-free optical imaging technique for studying inhomogeneous systems. However, the complicating influence of the nonresonant response on the CARS signal severely limits its sensitivity and specificity and especially limits the extent to which CARS microscopy has been used as a fully quantitative imaging technique. On the basis of spectral focusing mechanism, we establish a dual-soliton Stokes based CARS microspectroscopy and microscopy scheme capable of quantifying the spatial information of densities and chemical composition within inhomogeneous samples, using a single fiber laser. Dual-soliton Stokes scheme not only removes the nonresonant background but also allows robust acquisition of multiple characteristic vibrational frequencies. This all-fiber based laser source can cover the entire fingerprint (800-2200 cm−1) region with a spectral resolution of 15 cm−1. We demonstrate that quantitative degree determination of lipid-chain unsaturation in the fatty acids mixture can be achieved by the characterization of C = C stretching and CH2 deformation vibrations. For microscopy purposes, we show that the spatially inhomogeneous distribution of lipid droplets can be further quantitatively visualized using this quantified degree of lipid unsaturation in the acyl chain for contrast in the hyperspectral CARS images. The combination of compact excitation source and background-free capability to facilitate extraction of quantitative composition information with multiplex spectral peaks will enable wider applications of quantitative chemical imaging in studying biological and material systems. PMID:27867704

  6. New Astrometric Limits on the Stochastic Gravitational Wave Background

    NASA Astrophysics Data System (ADS)

    Darling, Jeremiah K.; Truebenbach, Alexandra; Paine, Jennie

    2018-06-01

    We present new limits on the low frequency (f < 10-8 Hz) stochastic gravitational wave background using correlated extragalactic proper motions. The familiar methods for gravitational wave detection are ground- and space-based laser interferometry, pulsar timing, and polarization of the cosmic microwave background. Astrometry offers an additional path to gravitational wave detection because gravitational waves deflect the light rays of extragalactic objects, creating apparent proper motions in a quadrupolar (and higher order modes) pattern. Astrometry is sensitive to gravitational waves with frequencies between roughly 10-18 Hz and 10-8 Hz (between H0 and 1/3 yr-1), which overlaps and bridges the pulsar timing and CMB polarization regimes. We present the methods and results of two complementary approaches to astrometric gravitational wave detection: (1) a small ~500-object radio interferometric sample with low per-source proper motion uncertainty but large intrinsic proper motions caused by radio jets, and (2) a thousand-fold larger sample with large per-source uncertainties that has small intrinsic proper motions (Gaia active galactic nuclei). Both approaches produce limits on ΩGW, the energy density of gravitational waves as a fraction of the cosmological critical energy density.The authors acknowledge support from the NSF grant AST-1411605 and the NASA grant 14-ATP14-0086.

  7. Attention-training with children from socioeconomically disadvantaged backgrounds in Cape Town.

    PubMed

    Schrieff-Elson, Leigh E; Ockhuizen, Ju-Reyn H; During, Genevieve; Thomas, Kevin G F

    2017-09-01

    Attention is a core process underlying competence in higher-order cognitive abilities. Previous research suggests that healthy children from low socioeconomic status (SES) backgrounds perform poorly, relative to those from higher SES backgrounds, on tasks assessing attentional abilities. In this pilot study, we investigated the effects of an attention-training intervention on task performance in low-SES children. We conducted a quasi-controlled trial with stratified randomisation, using a pre-test/ post-test design. Participants were low-SES children aged 7-13 years. Each was assigned to either an intervention group, a play control group, or a test-only control group (n = 5 per group). We implemented a ten-week manualised cognitive rehabilitation program, Pay Attention!, administering standardised tests of attention, working memory, and inhibition before and after the intervention. Between- and within-group analyses and Reliable Change Index statistics evaluated differences in scores from pre- to post-intervention. Analyses detected no notable between-group differences at either pre- or post-intervention testing. However, on tests of selective attention, attentional control, and inhibition, there were significant within-group and positive individual reliable changes exclusive to the intervention-group participants. Given the variability in our findings, more research needs be conducted with a larger sample to determine, with greater rigour, the efficacy of the intervention within samples of healthy children from low-SES backgrounds.

  8. Analysis on the application of background parameters on remote sensing classification

    NASA Astrophysics Data System (ADS)

    Qiao, Y.

    Drawing accurate crop cultivation acreage, dynamic monitoring of crops growing and yield forecast are some important applications of remote sensing to agriculture. During the 8th 5-Year Plan period, the task of yield estimation using remote sensing technology for the main crops in major production regions in China once was a subtopic to the national research task titled "Study on Application of Remote sensing Technology". In 21 century in a movement launched by Chinese Ministry of Agriculture to combine high technology to farming production, remote sensing has given full play to farm crops' growth monitoring and yield forecast. And later in 2001 Chinese Ministry of Agriculture entrusted the Northern China Center of Agricultural Remote Sensing to forecast yield of some main crops like wheat, maize and rice in rather short time to supply information for the government decision maker. Present paper is a report for this task. It describes the application of background parameters in image recognition, classification and mapping with focuses on plan of the geo-science's theory, ecological feature and its cartographical objects or scale, the study of phrenology for image optimal time for classification of the ground objects, the analysis of optimal waveband composition and the application of background data base to spatial information recognition ;The research based on the knowledge of background parameters is indispensable for improving the accuracy of image classification and mapping quality and won a secondary reward of tech-science achievement from Chinese Ministry of Agriculture. Keywords: Spatial image; Classification; Background parameter

  9. Evaluation of ultra-low background materials for uranium and thorium using ICP-MS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoppe, E. W.; Overman, N. R.; LaFerriere, B. D.

    2013-08-08

    An increasing number of physics experiments require low background materials for their construction. The presence of Uranium and Thorium and their progeny in these materials present a variety of unwanted background sources for these experiments. The sensitivity of the experiments continues to drive the necessary levels of detection ever lower as well. This requirement for greater sensitivity has rendered direct radioassay impractical in many cases requiring large quantities of material, frequently many kilograms, and prolonged counting times, often months. Other assay techniques have been employed such as Neutron Activation Analysis but this requires access to expensive facilities and instrumentation andmore » can be further complicated and delayed by the formation of unwanted radionuclides. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a useful tool and recent advancements have increased the sensitivity particularly in the elemental high mass range of U and Th. Unlike direct radioassay, ICP-MS is a destructive technique since it requires the sample to be in liquid form which is aspirated into a high temperature plasma. But it benefits in that it usually requires a very small sample, typically about a gram. This paper discusses how a variety of low background materials such as copper, polymers, and fused silica are made amenable to ICP-MS assay and how the arduous task of maintaining low backgrounds of U and Th is achieved.« less

  10. Evaluation of Ultra-Low Background Materials for Uranium and Thorium Using ICP-MS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoppe, Eric W.; Overman, Nicole R.; LaFerriere, Brian D.

    2013-08-08

    An increasing number of physics experiments require low background materials for their construction. The presence of Uranium and Thorium and their progeny in these materials present a variety of unwanted background sources for these experiments. The sensitivity of the experiments continues to drive the necessary levels of detection ever lower as well. This requirement for greater sensitivity has rendered direct radioassay impractical in many cases requiring large quantities of material, frequently many kilograms, and prolonged counting times, often months. Other assay techniques have been employed such as Neutron Activation Analysis but this requires access to expensive facilities and instrumentation andmore » can be further complicated and delayed by the formation of unwanted radionuclides. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a useful tool and recent advancements have increased the sensitivity particularly in the elemental high mass range of U and Th. Unlike direct radioassay, ICP-MS is a destructive technique since it requires the sample to be in liquid form which is aspirated into a high temperature plasma. But it benefits in that it usually requires a very small sample, typically about a gram. Here we will discuss how a variety of low background materials such as copper, polymers, and fused silica are made amenable to ICP-MS assay and how the arduous task of maintaining low backgrounds of U and Th is achieved.« less

  11. Estimation of channel parameters and background irradiance for free-space optical link.

    PubMed

    Khatoon, Afsana; Cowley, William G; Letzepis, Nick; Giggenbach, Dirk

    2013-05-10

    Free-space optical communication can experience severe fading due to optical scintillation in long-range links. Channel estimation is also corrupted by background and electrical noise. Accurate estimation of channel parameters and scintillation index (SI) depends on perfect removal of background irradiance. In this paper, we propose three different methods, the minimum-value (MV), mean-power (MP), and maximum-likelihood (ML) based methods, to remove the background irradiance from channel samples. The MV and MP methods do not require knowledge of the scintillation distribution. While the ML-based method assumes gamma-gamma scintillation, it can be easily modified to accommodate other distributions. Each estimator's performance is compared using simulation data as well as experimental measurements. The estimators' performance are evaluated from low- to high-SI areas using simulation data as well as experimental trials. The MV and MP methods have much lower complexity than the ML-based method. However, the ML-based method shows better SI and background-irradiance estimation performance.

  12. Two Visual Pathways in Primates Based on Sampling of Space: Exploitation and Exploration of Visual Information

    PubMed Central

    Sheth, Bhavin R.; Young, Ryan

    2016-01-01

    Evidence is strong that the visual pathway is segregated into two distinct streams—ventral and dorsal. Two proposals theorize that the pathways are segregated in function: The ventral stream processes information about object identity, whereas the dorsal stream, according to one model, processes information about either object location, and according to another, is responsible in executing movements under visual control. The models are influential; however recent experimental evidence challenges them, e.g., the ventral stream is not solely responsible for object recognition; conversely, its function is not strictly limited to object vision; the dorsal stream is not responsible by itself for spatial vision or visuomotor control; conversely, its function extends beyond vision or visuomotor control. In their place, we suggest a robust dichotomy consisting of a ventral stream selectively sampling high-resolution/focal spaces, and a dorsal stream sampling nearly all of space with reduced foveal bias. The proposal hews closely to the theme of embodied cognition: Function arises as a consequence of an extant sensory underpinning. A continuous, not sharp, segregation based on function emerges, and carries with it an undercurrent of an exploitation-exploration dichotomy. Under this interpretation, cells of the ventral stream, which individually have more punctate receptive fields that generally include the fovea or parafovea, provide detailed information about object shapes and features and lead to the systematic exploitation of said information; cells of the dorsal stream, which individually have large receptive fields, contribute to visuospatial perception, provide information about the presence/absence of salient objects and their locations for novel exploration and subsequent exploitation by the ventral stream or, under certain conditions, the dorsal stream. We leverage the dichotomy to unify neuropsychological cases under a common umbrella, account for the increased

  13. Two Visual Pathways in Primates Based on Sampling of Space: Exploitation and Exploration of Visual Information.

    PubMed

    Sheth, Bhavin R; Young, Ryan

    2016-01-01

    Evidence is strong that the visual pathway is segregated into two distinct streams-ventral and dorsal. Two proposals theorize that the pathways are segregated in function: The ventral stream processes information about object identity, whereas the dorsal stream, according to one model, processes information about either object location, and according to another, is responsible in executing movements under visual control. The models are influential; however recent experimental evidence challenges them, e.g., the ventral stream is not solely responsible for object recognition; conversely, its function is not strictly limited to object vision; the dorsal stream is not responsible by itself for spatial vision or visuomotor control; conversely, its function extends beyond vision or visuomotor control. In their place, we suggest a robust dichotomy consisting of a ventral stream selectively sampling high-resolution/ focal spaces, and a dorsal stream sampling nearly all of space with reduced foveal bias. The proposal hews closely to the theme of embodied cognition: Function arises as a consequence of an extant sensory underpinning. A continuous, not sharp, segregation based on function emerges, and carries with it an undercurrent of an exploitation-exploration dichotomy. Under this interpretation, cells of the ventral stream, which individually have more punctate receptive fields that generally include the fovea or parafovea, provide detailed information about object shapes and features and lead to the systematic exploitation of said information; cells of the dorsal stream, which individually have large receptive fields, contribute to visuospatial perception, provide information about the presence/absence of salient objects and their locations for novel exploration and subsequent exploitation by the ventral stream or, under certain conditions, the dorsal stream. We leverage the dichotomy to unify neuropsychological cases under a common umbrella, account for the increased

  14. Robust Data Detection for the Photon-Counting Free-Space Optical System With Implicit CSI Acquisition and Background Radiation Compensation

    NASA Astrophysics Data System (ADS)

    Song, Tianyu; Kam, Pooi-Yuen

    2016-02-01

    Since atmospheric turbulence and pointing errors cause signal intensity fluctuations and the background radiation surrounding the free-space optical (FSO) receiver contributes an undesired noisy component, the receiver requires accurate channel state information (CSI) and background information to adjust the detection threshold. In most previous studies, for CSI acquisition, pilot symbols were employed, which leads to a reduction of spectral and energy efficiency; and an impractical assumption that the background radiation component is perfectly known was made. In this paper, we develop an efficient and robust sequence receiver, which acquires the CSI and the background information implicitly and requires no knowledge about the channel model information. It is robust since it can automatically estimate the CSI and background component and detect the data sequence accordingly. Its decision metric has a simple form and involves no integrals, and thus can be easily evaluated. A Viterbi-type trellis-search algorithm is adopted to improve the search efficiency, and a selective-store strategy is adopted to overcome a potential error floor problem as well as to increase the memory efficiency. To further simplify the receiver, a decision-feedback symbol-by-symbol receiver is proposed as an approximation of the sequence receiver. By simulations and theoretical analysis, we show that the performance of both the sequence receiver and the symbol-by-symbol receiver, approach that of detection with perfect knowledge of the CSI and background radiation, as the length of the window for forming the decision metric increases.

  15. Effects of packaging and storage conditions on the quality of amoxicillin-clavulanic acid – an analysis of Cambodian samples

    PubMed Central

    2013-01-01

    Background The use of substandard and degraded medicines is a major public health problem in developing countries such as Cambodia. A collaborative study was conducted to evaluate the quality of amoxicillin–clavulanic acid preparations under tropical conditions in a developing country. Methods Amoxicillin-clavulanic acid tablets were obtained from outlets in Cambodia. Packaging condition, printed information, and other sources of information were examined. The samples were tested for quantity, content uniformity, and dissolution. Authenticity was verified with manufacturers and regulatory authorities. Results A total of 59 samples were collected from 48 medicine outlets. Most (93.2%) of the samples were of foreign origin. Using predetermined acceptance criteria, 12 samples (20.3%) were non-compliant. Eight (13.6%), 10 (16.9%), and 20 (33.9%) samples failed quantity, content uniformity, and dissolution tests, respectively. Samples that violated our observational acceptance criteria were significantly more likely to fail the quality tests (Fisher’s exact test, p < 0.05). Conclusions Improper packaging and storage conditions may reduce the quality of amoxicillin–clavulanic acid preparations at community pharmacies. Strict quality control measures are urgently needed to maintain the quality of amoxicillin–clavulanic acid in tropical countries. PMID:23773420

  16. ADHD knowledge, perceptions, and information sources: perspectives from a community sample of adolescents and their parents.

    PubMed

    Bussing, Regina; Zima, Bonnie T; Mason, Dana M; Meyer, Johanna M; White, Kimberly; Garvan, Cynthia W

    2012-12-01

    The chronic illness model advocates for psychoeducation within a collaborative care model to enhance outcomes. To inform psychoeducational approaches for ADHD, this study describes parent and adolescent knowledge, perceptions, and information sources and explores how these vary by sociodemographic characteristics, ADHD risk, and past child mental health service use. Parents and adolescents were assessed 7.7 years after initial school district screening for ADHD risk. The study sample included 374 adolescents (56% high and 44% low ADHD risk) aged, on average, 15.4 (standard deviation = 1.8) years, and 36% were African American. Survey questions assessed ADHD knowledge, perceptions, and cues to action and elicited used and preferred information sources. Multiple logistic regression was used to determine potential independent predictors of ADHD knowledge. McNemar tests compared information source utilization against preference. Despite relatively high self-rated ADHD familiarity, misperceptions among parents and adolescents were common, including a sugar etiology (25% and 27%, respectively) and medication overuse (85% and 67%, respectively). African American respondents expressed less ADHD awareness and greater belief in sugar etiology than Caucasians. Parents used a wide range of ADHD information sources, whereas adolescents relied on social network members and teachers/school. However, parents and adolescents expressed similar strong preferences for the Internet (49% and 51%, respectively) and doctor (40% and 27%, respectively) as ADHD information sources. Culturally appropriate psychoeducational strategies are needed that combine doctor-provided ADHD information with reputable Internet sources. Despite time limitations during patient visits, both parents and teens place high priority on receiving information from their doctor. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  17. Mathematics Performance and the Role Played by Affective and Background Factors

    ERIC Educational Resources Information Center

    Grootenboer, Peter; Hemmings, Brian

    2007-01-01

    In this article, we report on a study examining those factors which contribute to the mathematics performance of a sample of children aged between 8 and 13 years. The study was designed specifically to consider the potency of a number of mathematical affective factors, as well as background characteristics (viz., gender, ethnicity, and…

  18. Traceability information carriers. The technology backgrounds and consumers' perceptions of the technological solutions.

    PubMed

    Chrysochou, Polymeros; Chryssochoidis, George; Kehagia, Olga

    2009-12-01

    The implementation of traceability in the food supply chain has reinforced adoption of technologies with the ability to track forward and trace back product-related information. Based on the premise that these technologies can be used as a means to provide product-related information to consumers, this paper explores the perceived benefits and drawbacks of such technologies. The aim is to identify factors that influence consumers' perceptions of such technologies, and furthermore to advise the agri-food business on issues that they should consider prior to the implementation of such technologies in their production lines. For the purposes of the study, a focus group study was conducted across 12 European countries, while a set of four different technologies used as a means to provide traceability information to consumers was the focal point of the discussions in each focus group. Results show that the amount of and confidence in the information provided, perceived levels of convenience, impact on product quality and safety, impact on consumers' health and the environment, and potential consequences on ethical and privacy liberties constitute important factors influencing consumers' perceptions of technologies that provide traceability.

  19. Sampling plans, selective insecticides and sustainability: the case for IPM as 'informed pest management'.

    PubMed

    Castle, Steven; Naranjo, Steven E

    2009-12-01

    Integrated Pest Management (IPM) is considered the central paradigm of insect pest management and is often characterized as a comprehensive use of multiple control tactics to reduce pest status while minimizing economic and environmental costs. As the principal precursor of IPM, the integrated control concept formulated the economic theory behind pest management decisions and specified an applied methodology for carrying out pest control. Sampling, economic thresholds and selective insecticides were three of the critical elements of that methodology and are now considered indispensable to the goals of IPM. We examine each of these elements in the context of contemporaneous information as well as accumulated experience and knowledge required for their skillful implementation in an IPM program. We conclude that while IPM is principally about integrating control tactics into an effective and sustainable approach to pest control, this overarching goal can only be achieved through well-trained practitioners, knowledgeable of the tenets conceived in the integrated control concept that ultimately yield informed pest management. (c) 2009 Society of Chemical Industry.

  20. The limits of arousal's memory-impairing effects on nearby information.

    PubMed

    Mather, Mara; Gorlick, Marissa A; Nesmith, Kathryn

    2009-01-01

    Showing an arousing central stimulus in a scene often leads to enhanced memory for the arousing central information and impaired memory for peripheral details. However, it is not clear from previous work whether arousing stimuli impair memory for all nonarousing nearby information or just background information. In several experiments, we tested how emotionally arousing pictures affect memory for nearby pictures and for background information. We found that when 2 pictures were presented together, an arousing picture did not affect item and location memory for the other picture. In contrast, an arousing picture impaired memory for a background pattern. These findings suggest that arousal impairs memory for information that is the target of perceptual suppression, such as background information when there is a figure-ground distinction, but does not impair memory for other foreground information.

  1. Background-free coherent anti-stokes Raman scattering of gas- and liquid-phase samples in a mesoporous silica aerogel host.

    PubMed

    Konorov, Stanislav O; Turner, Robin F B; Blades, Michael W

    2007-05-01

    Efficient time-resolved coherent anti-Stokes Raman scattering (CARS) of atmospheric nitrogen and ethanol trapped in a nanoporous silica aerogel matrix is demonstrated. Silica aerogel hosts are attractive for analytical CARS spectroscopy due to their high porosity/low density, low refractive index, and low scattering cross-section. Differences between the resonant and nonresonant parts of the nonlinear optical susceptibilities lead to much longer relaxation times for analytes compared to the matrix. Time-resolved CARS can then be used to obtain a nearly background-free measurement at characteristic vibrations of the analyte. These results demonstrate the potential of this approach for rapid, sensitive, background-free analyses of analytes entrapped in the aerogel pores, which may be advantageous for some environmental, chemical, and biological sensing applications.

  2. Monte Carlo Algorithms for a Bayesian Analysis of the Cosmic Microwave Background

    NASA Technical Reports Server (NTRS)

    Jewell, Jeffrey B.; Eriksen, H. K.; ODwyer, I. J.; Wandelt, B. D.; Gorski, K.; Knox, L.; Chu, M.

    2006-01-01

    A viewgraph presentation on the review of Bayesian approach to Cosmic Microwave Background (CMB) analysis, numerical implementation with Gibbs sampling, a summary of application to WMAP I and work in progress with generalizations to polarization, foregrounds, asymmetric beams, and 1/f noise is given.

  3. [Background and characteristics of migration to urban areas in Java].

    PubMed

    Kawamoto, I

    1985-06-01

    A review of urbanization trends in Java, Indonesia, is presented, with the focus on the background and characteristics of migrants to urban areas. Comparisons are made between the characteristics of laborers in the informal sector (housemaids) and those of factory workers, and between migrants from rural areas and those from other urban areas. (summary in ENG)

  4. [A comparison of convenience sampling and purposive sampling].

    PubMed

    Suen, Lee-Jen Wu; Huang, Hui-Man; Lee, Hao-Hsien

    2014-06-01

    Convenience sampling and purposive sampling are two different sampling methods. This article first explains sampling terms such as target population, accessible population, simple random sampling, intended sample, actual sample, and statistical power analysis. These terms are then used to explain the difference between "convenience sampling" and purposive sampling." Convenience sampling is a non-probabilistic sampling technique applicable to qualitative or quantitative studies, although it is most frequently used in quantitative studies. In convenience samples, subjects more readily accessible to the researcher are more likely to be included. Thus, in quantitative studies, opportunity to participate is not equal for all qualified individuals in the target population and study results are not necessarily generalizable to this population. As in all quantitative studies, increasing the sample size increases the statistical power of the convenience sample. In contrast, purposive sampling is typically used in qualitative studies. Researchers who use this technique carefully select subjects based on study purpose with the expectation that each participant will provide unique and rich information of value to the study. As a result, members of the accessible population are not interchangeable and sample size is determined by data saturation not by statistical power analysis.

  5. Strain Background Modifies Phenotypes in the ATP8B1-Deficient Mouse

    PubMed Central

    Vargas, Julie C.; Xu, Hongmei; Groen, Annamiek; Paulusma, Coen C.; Grenert, James P.; Pawlikowska, Ludmila; Sen, Saunak; Elferink, Ronald P. J. Oude; Bull, Laura N.

    2010-01-01

    Background Mutations in ATP8B1 (FIC1) underlie cases of cholestatic disease, ranging from chronic and progressive (progressive familial intrahepatic cholestasis) to intermittent (benign recurrent intrahepatic cholestasis). The ATP8B1-deficient mouse serves as an animal model of human ATP8B1 deficiency. Methodology/Principal Findings We investigated the effect of genetic background on phenotypes of ATP8B1-deficient and wild-type mice, using C57Bl/6 (B6), 129, and (B6-129) F1 strain backgrounds. B6 background resulted in greater abnormalities in ATP8B1-deficient mice than did 129 and/or F1 background. ATP8B1-deficient pups of B6 background gained less weight. In adult ATP8B1-deficient mice at baseline, those of B6 background had lower serum cholesterol levels, higher serum alkaline phosphatase levels, and larger livers. After challenge with cholate-supplemented diet, these mice exhibited higher serum alkaline phosphatase and bilirubin levels, greater weight loss and larger livers. ATP8B1-deficient phenotypes in mice of F1 and 129 backgrounds are usually similar, suggesting that susceptibility to manifestations of ATP8B1 deficiency may be recessive. We also detected differences in hepatobiliary phenotypes between wild-type mice of differing strains. Conclusions/Significance Our results indicate that the ATP8B1-deficient mouse in a B6 background may be a better model of human ATP8B1 deficiency and highlight the importance of informed background strain selection for mouse models of liver disease. PMID:20126555

  6. The Lunar Sample Compendium

    NASA Technical Reports Server (NTRS)

    Meyer, Charles

    2009-01-01

    The Lunar Sample Compendium is a succinct summary of the data obtained from 40 years of study of Apollo and Luna samples of the Moon. Basic petrographic, chemical and age information is compiled, sample-by-sample, in the form of an advanced catalog in order to provide a basic description of each sample. The LSC can be found online using Google. The initial allocation of lunar samples was done sparingly, because it was realized that scientific techniques would improve over the years and new questions would be formulated. The LSC is important because it enables scientists to select samples within the context of the work that has already been done and facilitates better review of proposed allocations. It also provides back up material for public displays, captures information found only in abstracts, grey literature and curatorial databases and serves as a ready access to the now-vast scientific literature.

  7. Two-sample discrimination of Poisson means

    NASA Technical Reports Server (NTRS)

    Lampton, M.

    1994-01-01

    This paper presents a statistical test for detecting significant differences between two random count accumulations. The null hypothesis is that the two samples share a common random arrival process with a mean count proportional to each sample's exposure. The model represents the partition of N total events into two counts, A and B, as a sequence of N independent Bernoulli trials whose partition fraction, f, is determined by the ratio of the exposures of A and B. The detection of a significant difference is claimed when the background (null) hypothesis is rejected, which occurs when the observed sample falls in a critical region of (A, B) space. The critical region depends on f and the desired significance level, alpha. The model correctly takes into account the fluctuations in both the signals and the background data, including the important case of small numbers of counts in the signal, the background, or both. The significance can be exactly determined from the cumulative binomial distribution, which in turn can be inverted to determine the critical A(B) or B(A) contour. This paper gives efficient implementations of these tests, based on lookup tables. Applications include the detection of clustering of astronomical objects, the detection of faint emission or absorption lines in photon-limited spectroscopy, the detection of faint emitters or absorbers in photon-limited imaging, and dosimetry.

  8. Socio-Economic Background and Access to Internet as Correlates of Students' Achievement in Agricultural Science

    ERIC Educational Resources Information Center

    Adegoke, Sunday Paul; Osokoya, Modupe M.

    2015-01-01

    This study investigated access to internet and socio-economic background as correlates of students' achievement in Agricultural Science among selected Senior Secondary Schools Two Students in Ogbomoso South and North Local Government Areas. The study adopted multi-stage sampling technique. Simple random sampling was used to select 30 students from…

  9. Calculation of background effects on the VESUVIO eV neutron spectrometer

    NASA Astrophysics Data System (ADS)

    Mayers, J.

    2011-01-01

    The VESUVIO spectrometer at the ISIS pulsed neutron source measures the momentum distribution n(p) of atoms by 'neutron Compton scattering' (NCS). Measurements of n(p) provide a unique window into the quantum behaviour of atomic nuclei in condensed matter systems. The VESUVIO 6Li-doped neutron detectors at forward scattering angles were replaced in February 2008 by yttrium aluminium perovskite (YAP)-doped γ-ray detectors. This paper compares the performance of the two detection systems. It is shown that the YAP detectors provide a much superior resolution and general performance, but suffer from a sample-dependent gamma background. This report details how this background can be calculated and data corrected. Calculation is compared with data for two different instrument geometries. Corrected and uncorrected data are also compared for the current instrument geometry. Some indications of how the gamma background can be reduced are also given.

  10. A study of nuclear recoil backgrounds in dark matter detectors

    NASA Astrophysics Data System (ADS)

    Westerdale, Shawn S.

    that informed the design of the DarkSide-50 boron-loaded liquid scintillator neutron veto. We describe the specific implementation of this veto system in DarkSide-50, including a description of its performance, and show that it can reject neutrons with a high enough efficiency to allow DarkSide-50 to run background-free for three years.

  11. A Study of Nuclear Recoil Backgrounds in Dark Matter Detectors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Westerdale, Shawn S.

    2016-01-01

    development that informed the design of the DarkSide-50 boron-loaded liquid scintillator neutron veto. We describe the specific implementation of this veto system in DarkSide-50, including a description of its performance, and show that it can reject neutrons with a high enough e_ciency to allow DarkSide-50 to run background-free for three years.« less

  12. What Do Children Learn about Biology from Factual Information? A Comparison of Interventions to Improve Understanding of Contagious Illnesses

    ERIC Educational Resources Information Center

    Myant, Katherine A.; Williams, Joanne M.

    2008-01-01

    Background: Children have been shown to hold misconceptions about illness, and previous work has indicated that their knowledge can be improved through the use of interventions. Aims: This study aims to evaluate interventions based on the provision of factual information for improving understanding of contagious illness. Sample: The participants…

  13. Metadata, Identifiers, and Physical Samples

    NASA Astrophysics Data System (ADS)

    Arctur, D. K.; Lenhardt, W. C.; Hills, D. J.; Jenkyns, R.; Stroker, K. J.; Todd, N. S.; Dassie, E. P.; Bowring, J. F.

    2016-12-01

    Physical samples are integral to much of the research conducted by geoscientists. The samples used in this research are often obtained at significant cost and represent an important investment for future research. However, making information about samples - whether considered data or metadata - available for researchers to enable discovery is difficult: a number of key elements related to samples are difficult to characterize in common ways, such as classification, location, sample type, sampling method, repository information, subsample distribution, and instrumentation, because these differ from one domain to the next. Unifying these elements or developing metadata crosswalks is needed. The iSamples (Internet of Samples) NSF-funded Research Coordination Network (RCN) is investigating ways to develop these types of interoperability and crosswalks. Within the iSamples RCN, one of its working groups, WG1, has focused on the metadata related to physical samples. This includes identifying existing metadata standards and systems, and how they might interoperate with the International Geo Sample Number (IGSN) schema (schema.igsn.org) in order to help inform leading practices for metadata. For example, we are examining lifecycle metadata beyond the IGSN `birth certificate.' As a first step, this working group is developing a list of relevant standards and comparing their various attributes. In addition, the working group is looking toward technical solutions to facilitate developing a linked set of registries to build the web of samples. Finally, the group is also developing a comparison of sample identifiers and locators. This paper will provide an overview and comparison of the standards identified thus far, as well as an update on the technical solutions examined for integration. We will discuss how various sample identifiers might work in complementary fashion with the IGSN to more completely describe samples, facilitate retrieval of contextual information, and

  14. Estimating the dim light melatonin onset of adolescents within a 6-h sampling window: the impact of sampling rate and threshold method

    PubMed Central

    Crowley, Stephanie J.; Suh, Christina; Molina, Thomas A.; Fogg, Louis F.; Sharkey, Katherine M.; Carskadon, Mary A.

    2016-01-01

    Objective/Background Circadian rhythm sleep-wake disorders often manifest during the adolescent years. Measurement of circadian phase such as the Dim Light Melatonin Onset (DLMO) improves diagnosis and treatment of these disorders, but financial and time costs limit the use of DLMO phase assessments in clinic. The current analysis aims to inform a cost-effective and efficient protocol to measure the DLMO in older adolescents by reducing the number of samples and total sampling duration. Patients/Methods A total of 66 healthy adolescents (26 males) aged 14.8 to 17.8 years participated in a study in which sleep was fixed for one week before they came to the laboratory for saliva collection in dim light (<20 lux). Two partial 6-h salivary melatonin profiles were derived for each participant. Both profiles began 5 h before bedtime and ended 1 h after bedtime, but one profile was derived from samples taken every 30 mins (13 samples) and the other from samples taken every 60 mins (7 samples). Three standard thresholds (first 3 melatonin values mean + 2 SDs, 3 pg/mL, and 4 pg/mL) were used to compute the DLMO. Agreement between DLMOs derived from 30-min and 60-min sampling rates was determined using a Bland-Altman analysis; agreement between sampling rate DLMOs was defined as ± 1 h. Results and Conclusions Within a 6-h sampling window, 60-min sampling provided DLMO estimates that were within ± 1 h of DLMO from 30-min sampling, but only when an absolute threshold (3 pg/mL or 4 pg/mL) was used to compute the DLMO. Future analyses should be extended to include adolescents with circadian rhythm sleep-wake disorders. PMID:27318227

  15. Development of a multivariate tool to reject background in a WZ diboson search for the CDF experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cremonesi, Matteo

    In the frame of the strong on-going data analysis effort of the CDF collaboration at Fermilab, a method was developed by the candidate to improve the background rejection efficiency in the search for associated pair production of electroweak W, Z bosons. The performaces of the method for vetoing the tt background in a WZ/ZZ → fνqmore » $$\\bar{q}$$ diboson search are reported. The method was developed in the inclusive 2-jets sample and applied to the “tag-2 jets" region, the subsample defined by the request that the two jets carry beauty flavor. In this region the tt production is one of the largest backgrounds. The tt veto proceeds in two steps: first, a set of pre-selection cuts are applied in a candidate sample where up to two leptons are accepted in addition to a jet pair, and the ZZ component of the signal is thus preserved; next, a Neural Network is trained to indicate the probability that the event be top-pair production. To validate the the method as developed in the inclusive 2-jets sample, it is applied to veto region providing a significant rejection of this important background.« less

  16. A flat Universe from high-resolution maps of the cosmic microwave background radiation

    PubMed

    de Bernardis P; Ade; Bock; Bond; Borrill; Boscaleri; Coble; Crill; De Gasperis G; Farese; Ferreira; Ganga; Giacometti; Hivon; Hristov; Iacoangeli; Jaffe; Lange; Martinis; Masi; Mason; Mauskopf; Melchiorri; Miglio; Montroy; Netterfield

    2000-04-27

    The blackbody radiation left over from the Big Bang has been transformed by the expansion of the Universe into the nearly isotropic 2.73 K cosmic microwave background. Tiny inhomogeneities in the early Universe left their imprint on the microwave background in the form of small anisotropies in its temperature. These anisotropies contain information about basic cosmological parameters, particularly the total energy density and curvature of the Universe. Here we report the first images of resolved structure in the microwave background anisotropies over a significant part of the sky. Maps at four frequencies clearly distinguish the microwave background from foreground emission. We compute the angular power spectrum of the microwave background, and find a peak at Legendre multipole Ipeak = (197 +/- 6), with an amplitude delta T200 = (69 +/- 8) microK. This is consistent with that expected for cold dark matter models in a flat (euclidean) Universe, as favoured by standard inflationary models.

  17. Clustering document fragments using background color and texture information

    NASA Astrophysics Data System (ADS)

    Chanda, Sukalpa; Franke, Katrin; Pal, Umapada

    2012-01-01

    Forensic analysis of questioned documents sometimes can be extensively data intensive. A forensic expert might need to analyze a heap of document fragments and in such cases to ensure reliability he/she should focus only on relevant evidences hidden in those document fragments. Relevant document retrieval needs finding of similar document fragments. One notion of obtaining such similar documents could be by using document fragment's physical characteristics like color, texture, etc. In this article we propose an automatic scheme to retrieve similar document fragments based on visual appearance of document paper and texture. Multispectral color characteristics using biologically inspired color differentiation techniques are implemented here. This is done by projecting document color characteristics to Lab color space. Gabor filter-based texture analysis is used to identify document texture. It is desired that document fragments from same source will have similar color and texture. For clustering similar document fragments of our test dataset we use a Self Organizing Map (SOM) of dimension 5×5, where the document color and texture information are used as features. We obtained an encouraging accuracy of 97.17% from 1063 test images.

  18. Antigen detection based on background fluorescence quenching immunochromatographic assay.

    PubMed

    Chen, Xiangjun; Xu, Yangyang; Yu, Jinsheng; Li, Jiutong; Zhou, Xuelei; Wu, Chuanyong; Ji, Qiuliang; Ren, Yuan; Wang, Liqun; Huang, Zhengyi; Zhuang, Hanling; Piao, Long; Head, Richard; Wang, Yajie; Lou, Jiatao

    2014-09-02

    Gold immunochromatographic assay (GICA) has been around for quite a while, but it is qualitative in the vast majority of applications. A fast, simple and quantitative GICA is in call for better medicine. In the current study, we have established a novel, quantitative GICA based on fluorescence quenching and nitrocellulose membrane background signals, called background fluorescence quenching immunochromatographic assay (bFQICA). Using model analyte alpha-fetoprotein (AFP), the present study assessed the performance of bFQICA in numerous assay aspects. With serial dilutions of the international AFP standard, standard curves for the calculation of AFP concentration were successfully established. At 10 and 100ngmL(-1) of the international AFP standard, the assay variability was defined with a coefficient of variance at 10.4% and 15.2%, respectively. For samples with extended range of AFP levels, bFQICA was able to detect AFP at as low as 1ngmL(-1). Fluorescence in bFQICA strips stayed constant over months. A good correlation between the results from bFQICA and from a well-established Roche electrochemiluminescence immunoassay was observed in 27 serum samples (r=0.98, p<0.001). In conclusion, our study has demonstrated distinctive features of bFQICA over conventional GICA, including utilization of a unique fluorescence ratio between nitrocellulose membrane background and specific signals (F1/F2) to ensure accurate measurements, combined qualitative and quantitative capabilities, and exceptionally high sensitivity for detection of very low levels of antigens. All of these features could make bFQICA attractive as a model for antigen-antibody complex based GICA, and could promote bFQICA to a broad range of applications for investigation of a variety of diseases. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.

    PubMed

    Struwe, Weston B; Agravat, Sanjay; Aoki-Kinoshita, Kiyoko F; Campbell, Matthew P; Costello, Catherine E; Dell, Anne; Ten Feizi; Haslam, Stuart M; Karlsson, Niclas G; Khoo, Kay-Hooi; Kolarich, Daniel; Liu, Yan; McBride, Ryan; Novotny, Milos V; Packer, Nicolle H; Paulson, James C; Rapp, Erdmann; Ranzinger, Rene; Rudd, Pauline M; Smith, David F; Tiemeyer, Michael; Wells, Lance; York, William S; Zaia, Joseph; Kettner, Carsten

    2016-09-01

    The minimum information required for a glycomics experiment (MIRAGE) project was established in 2011 to provide guidelines to aid in data reporting from all types of experiments in glycomics research including mass spectrometry (MS), liquid chromatography, glycan arrays, data handling and sample preparation. MIRAGE is a concerted effort of the wider glycomics community that considers the adaptation of reporting guidelines as an important step towards critical evaluation and dissemination of datasets as well as broadening of experimental techniques worldwide. The MIRAGE Commission published reporting guidelines for MS data and here we outline guidelines for sample preparation. The sample preparation guidelines include all aspects of sample generation, purification and modification from biological and/or synthetic carbohydrate material. The application of MIRAGE sample preparation guidelines will lead to improved recording of experimental protocols and reporting of understandable and reproducible glycomics datasets. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. The limits of arousal's memory impairing effects on nearby information

    PubMed Central

    Mather, Mara; Gorlick, Marissa; Nesmith, Kathryn

    2009-01-01

    Showing an arousing central stimulus in a scene often leads to enhanced memory for the arousing central information and impaired memory for peripheral details. However, it is not clear from previous work whether arousing stimuli impair memory for all non-arousing nearby information or just background information. In several experiments, we tested how emotionally arousing pictures affect memory for nearby pictures and for background information. We found that when two pictures were presented together, having one of the pictures be arousing did not affect item and location memory for the other picture. In contrast, an arousing picture impaired memory for a background pattern. These findings suggest that arousal impairs memory for information that is the target of perceptual suppression, such as background information when there is a figure-ground distinction, but does not impair memory for other foreground information. PMID:19827704

  1. A Sparse-Sampled Redshift Survey of IRAS Galaxies - Part One - the Convergence of the IRAS Dipole and the Origin of Our Motion with Respect to the Microwave Background

    NASA Astrophysics Data System (ADS)

    Rowan-Robinson, M.; Lawrence, A.; Saunders, W.; Crawford, J.; Ellis, R.; Frenk, C. S.; Parry, I.; Xiaoyang, X.; Allington-Smith, J.; Efstathiou, G.; Kaiser, N.

    1990-11-01

    We have carried out a sparse-sampled redshift survey of IRAS Point Source Catalog 60-micron sources, at a sampling rate of one in six. For a sample of 2163 sources with S>=0.6 Jy at |b|>10^deg^, we have redshifts for 2093, or 97 per cent. Of the sources, which were selected from the IRAS 60-micron Galaxy Catalogue of Rowan-Robinson et al., 1.2 per cent turned out to be galactic and 0.4 per cent are blank fields. Our survey reaches significantly deeper than the all-sky IRAS galaxy redshift survey of Strauss & Davis, which is complete to 1.94 Jy. We have used these data to investigate the convergence of the IRAS dipole. We find that the peculiar acceleration acting on the Local Group, as measured with IRAS galaxies, is generated within 100h^-1^ Mpc. For d<50h^-1^ Mpc, our estimate of the acceleration generated agrees with that of Strauss & Davis. However, we find that a non-negligible acceleration is generated between 50 and 100h^-1^ Mpc. The direction of the acceleration is consistent, within the uncertainties, with that of the microwave background dipole. The amplitude implies a value for the cosmological density parameter {OMEGA}_0_ = 0.7 (+0.3,-0.2) if the IRAS galaxy distribution traces that of the total mass. If {OMEGA}_0_ = 1, a bias parameter b = 1.23+/-0.23 is inferred. The convergence properties of the dipole are similar to those obtained from random locations in N-body simulations of a cold dark matter universe. Assuming that the IRAS galaxies trace the mass distribution, we predict a peculiar velocity for each galaxy in the survey, by calculating the dipole at each galaxy position, initially assuming distances based on velocities. We then construct a simple analytical model for this flow field, involving 12 massive clusters (including the prominent superclusters within 150h^-1^Mpc) correcting galaxy distances and peculiar velocities in an iterative procedure. The model clusters have large haloes in which the density is proportional to r^-1.6^, extending

  2. General Information About Injection Wells

    EPA Pesticide Factsheets

    This webpage provides general background information on injection wells used to place fluids in the subsurface. It also provides information on use, different categories, and how they are regulated. Information on the protection is also provided.

  3. The Qatar Biobank: background and methods.

    PubMed

    Al Kuwari, Hanan; Al Thani, Asma; Al Marri, Ajayeb; Al Kaabi, Abdulla; Abderrahim, Hadi; Afifi, Nahla; Qafoud, Fatima; Chan, Queenie; Tzoulaki, Ioanna; Downey, Paul; Ward, Heather; Murphy, Neil; Riboli, Elio; Elliott, Paul

    2015-12-03

    The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 years) aged ≥18 years (approximately one-fifth of all Qatari citizens), to follow up these same individuals over the long term to record any subsequent disease, and hence to study the causes and progression of disease, and disease burden, in the Qatari population. Between the 11(th)-December-2012 and 20(th)-February-2014, 1209 participants were recruited into the pilot study of the Qatar Biobank. At recruitment, extensive phenotype information was collected from each participant, including information/measurements of socio-demographic factors, prevalent health conditions, diet, lifestyle, anthropometry, body composition, bone health, cognitive function, grip strength, retinal imaging, total body dual energy X-ray absorptiometry, and measurements of cardiovascular and respiratory function. Blood, urine, and saliva were collected and stored for future research use. A panel of 66 clinical biomarkers was routinely measured on fresh blood samples in all participants. Rates of recruitment are to be progressively increased in the coming period and the recruitment base widened to achieve a cohort of consented individuals broadly representative of the eligible Qatari population. In addition, it is planned to add additional measures in sub-samples of the cohort, including Magnetic Resonance Imaging (MRI) of the brain, heart and abdomen. The mean time for collection of the extensive phenotypic information and biological samples from each participant at the baseline recruitment visit was 179 min. The 1209 pilot study participants (506 men and 703 women) were aged between 28-80 years (median 39 years); 899 (74.4%) were Qatari nationals and 310 (25.6%) were long-term residents. Approximately two-thirds of pilot participants were educated to graduate level or above. The

  4. Some Aspects of Developing Background Knowledge in Second Language Acquisition Revisited

    ERIC Educational Resources Information Center

    Zashchitina, Galina; Moysyak, Natalia

    2017-01-01

    The article focuses on defining how background knowledge impacts on second-language acquisition by giving a brief overview of schema theory, the interaction of the basic modes of information processing. A challenge of dealing with culturally specific texts in second language acquisition is also touched upon. Different research-supported views on…

  5. Depression literacy among Australians of Chinese-speaking background in Melbourne, Australia

    PubMed Central

    2010-01-01

    Background This study investigated the knowledge of depression and preference for professional help, medications and treatment methods among Australians of Chinese-speaking background, and the perceptions of this population of the causes of mental illness. Methods Adopting a cluster convenience sampling method, the study recruited 200 Chinese-speaking subjects from four major areas in metropolitan Melbourne where many Chinese live. The respondents were presented with a vignette describing an individual with depression and then asked questions to assess their understanding of depression and preference for professional help, medications and treatment methods. A comparative approach was used to compare the findings with those of a previous study of the mental health literacy of Australian and Japanese adults. Results Compared to the Australian and Japanese samples, a much lower percentage of Chinese-speaking Australians (14%) could correctly identify major depression described in the vignette, and a higher percentage believed that counseling professionals could be helpful. Higher percentages of those who believed that close family members could be helpful were found in the Chinese-speaking Australian and Japanese samples, and these two groups also expressed more uncertainty about the usefulness or harmfulness of certain medications compared to the Australian sample. Higher percentages of respondents in both the Chinese-speaking Australian and the Australian sample considered "lifestyle changes" to be helpful compared to the Japanese sample. In the Chinese-speaking sample, 30%, 17.4%, 33% and 27% of the respondents rated "traditional Chinese medicine doctors," "Chinese herbal medications," "taking Chinese nutritional foods/supplements" and "qiqong" as helpful. Many perceived "changing fungshui" and "traditional Chinese worship" to be harmful. Regarding the perception of causes of mental illness, items related to psychosocial perspectives including "life stress" and

  6. Polarization Observations with the Cosmic Background Imager

    NASA Astrophysics Data System (ADS)

    Cartwright, J. K.; Padin, S.; Pearson, T. J.; Readhead, A. C. S.; Shepherd, M. C.; Taylor, G. B.

    2000-12-01

    The linear polarization of the Cosmic Microwave Background Radiation is a fundamental prediction of the standard model. We report a limit on the polarization of the CMBR for l ~660. This limit was obtained with the Cosmic Background Imager, a 13 element interferometer which operates in the 26-36 GHz band from a site at 5000m in northern Chile. The array consists of 90-cm Cassegrain antennas mounted on a single, fully steerable platform; this platform can be rotated about the optical axis to facilitate polarization observations. The CBI employs single mode circularly polarized receivers, of which 12 are configured for LCP and one is configured for RCP. The 12 cross polarized baselines sample multipoles from l ~600 to l ~3500. The instrumental polarization of the CBI was calibrated with observations of 3C279, a bright polarized source which is unresolved by the CBI. Because the centimeter flux of 3C279 is variable, it was monitored twice per month for 8 months in '00 with the VLA at 22 and 43 GHz. These observations also established the stability of the polarization characteristics of the CBI. This work was made possible by NSF grant AST-9802989

  7. Constrained sampling experiments reveal principles of detection in natural scenes.

    PubMed

    Sebastian, Stephen; Abrams, Jared; Geisler, Wilson S

    2017-07-11

    A fundamental everyday visual task is to detect target objects within a background scene. Using relatively simple stimuli, vision science has identified several major factors that affect detection thresholds, including the luminance of the background, the contrast of the background, the spatial similarity of the background to the target, and uncertainty due to random variations in the properties of the background and in the amplitude of the target. Here we use an experimental approach based on constrained sampling from multidimensional histograms of natural stimuli, together with a theoretical analysis based on signal detection theory, to discover how these factors affect detection in natural scenes. We sorted a large collection of natural image backgrounds into multidimensional histograms, where each bin corresponds to a particular luminance, contrast, and similarity. Detection thresholds were measured for a subset of bins spanning the space, where a natural background was randomly sampled from a bin on each trial. In low-uncertainty conditions, both the background bin and the amplitude of the target were fixed, and, in high-uncertainty conditions, they varied randomly on each trial. We found that thresholds increase approximately linearly along all three dimensions and that detection accuracy is unaffected by background bin and target amplitude uncertainty. The results are predicted from first principles by a normalized matched-template detector, where the dynamic normalizing gain factor follows directly from the statistical properties of the natural backgrounds. The results provide an explanation for classic laws of psychophysics and their underlying neural mechanisms.

  8. Personal, Anticipated Information Need

    ERIC Educational Resources Information Center

    Bruce, Harry

    2005-01-01

    Background: The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in "Bookmarks" and "Favourites". Argument: It is suggested that personal information collections are…

  9. How do hospitalised patients with Turkish migration background estimate their language skills and their comprehension of medical information – a prospective cross-sectional study and comparison to native patients in Germany to assess the language barrier and the need for translation

    PubMed Central

    2013-01-01

    Background Today more than two million people with Turkish migration background live in Germany making them the largest ethnic minority in the country. Data concerning language skills and the perception of medical information in hospitalised patients with Turkish migration background (T) are scarce. Our study is the first to gather quantitative information on this important subject. Methods T and hospitalised German patients without migration background (G) of our university hospital were prospectively included into a cross-sectional study and completed a questionnaire - each group in the appropriate language (T: Turkish, G: German). Results 121 T and 121 G were included. Groups significantly differed in age (T: 44.9 ± 17.8, G: 56.9 ± 16.7y) and proportion of males (T: 37.2, G: 54.5%) but not regarding the proportion of college graduates (T: 19.3, G: 15.7%). The majority of T was born in Turkey (71%) and is of Turkish nationality (66%). 74% of T speak mainly Turkish at home; however, 73% speak German at work. 74.4% of T self-rated their German linguistic proficiency as “average” or better while 25.6% reported it as “very bad” or “bad”. 10.7% of T need translation in order to pursue everyday activities. T were significantly less satisfied with the physician’s information on disease and estimated to understand significantly less of what the physician told them: 46.3% of T estimated their reception of the physician’s information to be “average” or worse. 43.3% of T had the impression that it would have helped them “much” or “very much” to be aided by an interpreter at the hospital. The information transmitted while giving informed consent to invasive medical procedure was judged to be “mostly” or “completely” sufficient by the majority of T (76%) and G (89.8%). In this setting 37 of 96 T (38.5%) reported being helped by an interpreter – in most cases (64.9%) a family member. Conclusion Although the majority of

  10. Liquid scintillation sample analysis in microcentrifuge tubes.

    PubMed

    Elliott, J C

    1993-01-01

    Local regulations prohibiting drain disposal of "biodegradable" liquid scintillation cocktails prompted investigation of volume reduction for these materials. Microcentrifuge tubes were used with aqueous and filter media samples of 3H, 14C, 32P, and 125I. Backgrounds, counting efficiencies, figures of merit, and spectral distributions obtained for microcentrifuge tubes compared favorably to conventional vials. Differences in 32P spectra for solid support samples appeared related to filter material and sample volume. Decreases in sample costs and waste volume and disposal costs were approximately 50-75%.

  11. “ADHD Knowledge, Perceptions and Information Sources: Perspectives from a Community Sample of Adolescents and their Parents”

    PubMed Central

    Bussing, Regina; Zima, Bonnie T.; Mason, Dana M.; Meyer, Johanna.M.; White, Kimberly; Garvan, Cynthia W.

    2012-01-01

    PURPOSE The chronic illness model advocates for psychoeducation within a collaborative care model to enhance outcomes. To inform psychoeducational approaches for attention-deficit/hyperactivity disorder (ADHD), this study describes parent and adolescent knowledge, perceptions and information sources and explores how these vary by sociodemographic characteristics, ADHD risk, and past child mental health service use. METHODS Parents and adolescents were assessed 7.7 years after initial school district screening for ADHD risk. The study sample included 374 adolescents (56% high and 44% low ADHD risk), on average 15.4 (SD 1.8) years old, and 36% were African American. Survey questions assessed ADHD knowledge, perceptions, and cues to action, and elicited utilized and preferred information sources. Multiple logistic regression was used to determine potential independent predictors of ADHD knowledge. McNemar's tests compared information source utilization against preference. RESULTS Despite relatively high self-rated ADHD familiarity, misperceptions among parents and adolescents were common, including a sugar etiology (25% and 27%, respectively) and medication overuse (85% and 67%). African American respondents expressed lower ADHD awareness and greater belief in sugar etiology than Caucasians. Parents used a wide range of ADHD information sources while adolescents relied on social network members and teachers/school. However, parents and adolescents expressed similar strong preferences for the Internet (49% and 51%) and doctor (40% and 27%) as ADHD information sources. CONCLUSION Culturally appropriate psychoeducational strategies are needed that combine doctor-provided ADHD information with reputable Internet sources. Despite time limitations during patient visits, both parents and teens place high priority on receiving information from their doctor. PMID:23174470

  12. Lunar Sample Compendium

    NASA Technical Reports Server (NTRS)

    Meyer, Charles

    2005-01-01

    The purpose of the Lunar Sample Compendium will be to inform scientists, astronauts and the public about the various lunar samples that have been returned from the Moon. This Compendium will be organized rock by rock in the manor of a catalog, but will not be as comprehensive, nor as complete, as the various lunar sample catalogs that are available. Likewise, this Compendium will not duplicate the various excellent books and reviews on the subject of lunar samples (Cadogen 1981, Heiken et al. 1991, Papike et al. 1998, Warren 2003, Eugster 2003). However, it is thought that an online Compendium, such as this, will prove useful to scientists proposing to study individual lunar samples and should help provide backup information for lunar sample displays. This Compendium will allow easy access to the scientific literature by briefly summarizing the significant findings of each rock along with the documentation of where the detailed scientific data are to be found. In general, discussion and interpretation of the results is left to the formal reviews found in the scientific literature. An advantage of this Compendium will be that it can be updated, expanded and corrected as need be.

  13. Disaster Emergency Rapid Assessment Based on Remote Sensing and Background Data

    NASA Astrophysics Data System (ADS)

    Han, X.; Wu, J.

    2018-04-01

    The period from starting to the stable conditions is an important stage of disaster development. In addition to collecting and reporting information on disaster situations, remote sensing images by satellites and drones and monitoring results from disaster-stricken areas should be obtained. Fusion of multi-source background data such as population, geography and topography, and remote sensing monitoring information can be used in geographic information system analysis to quickly and objectively assess the disaster information. According to the characteristics of different hazards, the models and methods driven by the rapid assessment of mission requirements are tested and screened. Based on remote sensing images, the features of exposures quickly determine disaster-affected areas and intensity levels, and extract key disaster information about affected hospitals and schools as well as cultivated land and crops, and make decisions after emergency response with visual assessment results.

  14. Background considerations in the analysis of PIXE spectra by Artificial Neural Systems.

    NASA Astrophysics Data System (ADS)

    Correa, R.; Morales, J. R.; Requena, I.; Miranda, J.; Barrera, V. A.

    2016-05-01

    In order to study the importance of background in PIXE spectra to determine elemental concentrations in atmospheric aerosols using artificial neural systems ANS, two independently trained ANS were constructed, one which considered as input the net number of counts in the peak, and another which included the background. In the training and validation phases thirty eight spectra of aerosols collected in Santiago, Chile, were used. In both cases the elemental concentration values were similar. This fact was due to the intrinsic characteristic of ANS operating with normalized values of the net and total number of counts under the peaks, something that was verified in the analysis of 172 spectra obtained from aerosols collected in Mexico city. Therefore, networks operating under the mode which include background can reduce time and cost when dealing with large number of samples.

  15. Structured background grids for generation of unstructured grids by advancing front method

    NASA Technical Reports Server (NTRS)

    Pirzadeh, Shahyar

    1991-01-01

    A new method of background grid construction is introduced for generation of unstructured tetrahedral grids using the advancing-front technique. Unlike the conventional triangular/tetrahedral background grids which are difficult to construct and usually inadequate in performance, the new method exploits the simplicity of uniform Cartesian meshes and provides grids of better quality. The approach is analogous to solving a steady-state heat conduction problem with discrete heat sources. The spacing parameters of grid points are distributed over the nodes of a Cartesian background grid by interpolating from a few prescribed sources and solving a Poisson equation. To increase the control over the grid point distribution, a directional clustering approach is used. The new method is convenient to use and provides better grid quality and flexibility. Sample results are presented to demonstrate the power of the method.

  16. Implementing situation-background-assessment-recommendation in an anaesthetic clinic and subsequent information retention among receivers: A prospective interventional study of postoperative handovers.

    PubMed

    Randmaa, Maria; Swenne, Christine L; Mårtensson, Gunilla; Högberg, Hans; Engström, Maria

    2016-03-01

    Communication errors cause clinical incidents and adverse events in relation to surgery. To ensure proper postoperative patient care, it is essential that personnel remember and recall information given during the handover from the operating theatre to the postanaesthesia care unit. Formalizing the handover may improve communication and aid memory, but research in this area is lacking. The objective of this study was to evaluate whether implementing the communication tool Situation-Background-Assessment-Recommendation (SBAR) affects receivers' information retention after postoperative handover. A prospective intervention study with an intervention group and comparison nonintervention group, with assessments before and after the intervention. The postanaesthesia care units of two hospitals in Sweden during 2011 and 2012. Staff involved in the handover between the operating theatre and the postanaesthesia care units within each hospital. Implementation of the communication tool SBAR in one hospital. The main outcome was the percentage of recalled information sequences among receivers after the handover. Data were collected using both audio-recordings and observations recorded on a study-specific protocol form. Preintervention, 73 handovers were observed (intervention group, n = 40; comparison group, n = 33) involving 72 personnel (intervention group, n = 40; comparison group, n = 32). Postintervention, 91 handovers were observed (intervention group, n = 44; comparison group, n = 47) involving 57 personnel (intervention group, n = 31; comparison group, n = 26). In the intervention group, the percentage of recalled information sequences by the receivers increased from 43.4% preintervention to 52.6% postintervention (P = 0.004) and the SBAR structure improved significantly (P = 0.028). In the comparison group, the corresponding figures were 51.3 and 52.6% (P = 0.725) with no difference in SBAR structure. When a linear

  17. Coyle's Information Highway Handbook: A Practical File on the New Information Order.

    ERIC Educational Resources Information Center

    Coyle, Karen

    This book provides a selection of documentary background information on areas of the Information Highway debate that are particularly relevant to libraries. The book is designed for librarians who are online but have little time to explore the general areas of information policy, and for those not yet connected to the Internet who need to…

  18. Non-English Speaking Background Workers' Literacies--a Health and Safety Issue.

    ERIC Educational Resources Information Center

    Wyatt-Smith, Claire; Castleton, Geraldine

    1995-01-01

    Summarizes the experiences of workers from non-English-speaking backgrounds (NESB) in accessing safety information. The article examines the issue through the workers' eyes and focuses on the potential relationships between language and literacy and workplace health and safety and a concern for the reasons why some NESB workers are losers in…

  19. Effects of Classical Background Music on Stress, Anxiety, and Knowledge of Filipino Baccalaureate Nursing Students.

    PubMed

    Evangelista, Kevin; Macabasag, Romeo Luis A; Capili, Brylle; Castro, Timothy; Danque, Marilee; Evangelista, Hanzel; Rivero, Jenica Ana; Gonong, Michell Katrina; Diño, Michael Joseph; Cajayon, Sharon

    2017-10-28

    Previous work on the use of background music suggests conflicting results in various psychological, behavioral, and educational measures. This quasi-experiment examined the effect of integrating classical background music during a lecture on stress, anxiety, and knowledge. A total of 42 nursing students participated this study. We utilized independent sample t-test and multivariate analysis of variance to examine the effect of classical background music. Our findings suggest that the presence or absence of classical background music do not affect stress, anxiety, and knowledge scores (Λ = 0.999 F(3, 78) = 0.029, p = 0.993). We provided literature to explain the non-significant result. Although classical music failed to establish a significant influence on the dependent variables, classical background music during lecture hours can be considered a non-threatening stimulus. We recommend follow up studies regarding the role of classical background music in regulating attention control of nursing students during lecture hours.

  20. Information System Plan.

    ERIC Educational Resources Information Center

    McIntyre, Chuck

    Prepared for review and discussion by the Board of Governors of the California Community Colleges (CCC), this report provides background and recommendations for the refinement, expansion, and increased use of the information system of the CCC Chancellor's Office. Following introductory material proposing an expanded scope of the information system…

  1. Background Underground at WIPP

    NASA Astrophysics Data System (ADS)

    Esch, Ernst-Ingo; Hime, A.; Bowles, T. J.

    2001-04-01

    Recent interest to establish a dedicated underground laboratory in the United States prompted an experimental program at to quantify the enviromental backgrounds underground at the Waste Isolation Pilot Plant (WIPP) in Carlsbad, New Mexico. An outline of this program is provided along with recent experimental data on the cosmic ray muon flux at the 650 meter level of WIPP. The implications of the cosmic ray muon and fast neutron background at WIPP will be discussed in the context of new generation, low background experiments envisioned in the future.

  2. The EnzymeTracker: an open-source laboratory information management system for sample tracking.

    PubMed

    Triplet, Thomas; Butler, Gregory

    2012-01-26

    In many laboratories, researchers store experimental data on their own workstation using spreadsheets. However, this approach poses a number of problems, ranging from sharing issues to inefficient data-mining. Standard spreadsheets are also error-prone, as data do not undergo any validation process. To overcome spreadsheets inherent limitations, a number of proprietary systems have been developed, which laboratories need to pay expensive license fees for. Those costs are usually prohibitive for most laboratories and prevent scientists from benefiting from more sophisticated data management systems. In this paper, we propose the EnzymeTracker, a web-based laboratory information management system for sample tracking, as an open-source and flexible alternative that aims at facilitating entry, mining and sharing of experimental biological data. The EnzymeTracker features online spreadsheets and tools for monitoring numerous experiments conducted by several collaborators to identify and characterize samples. It also provides libraries of shared data such as protocols, and administration tools for data access control using OpenID and user/team management. Our system relies on a database management system for efficient data indexing and management and a user-friendly AJAX interface that can be accessed over the Internet. The EnzymeTracker facilitates data entry by dynamically suggesting entries and providing smart data-mining tools to effectively retrieve data. Our system features a number of tools to visualize and annotate experimental data, and export highly customizable reports. It also supports QR matrix barcoding to facilitate sample tracking. The EnzymeTracker was designed to be easy to use and offers many benefits over spreadsheets, thus presenting the characteristics required to facilitate acceptance by the scientific community. It has been successfully used for 20 months on a daily basis by over 50 scientists. The EnzymeTracker is freely available online at http

  3. Simple Elimination of Background Fluorescence in Formalin-Fixed Human Brain Tissue for Immunofluorescence Microscopy.

    PubMed

    Sun, Yulong; Ip, Philbert; Chakrabartty, Avijit

    2017-09-03

    Immunofluorescence is a common method used to visualize subcellular compartments and to determine the localization of specific proteins within a tissue sample. A great hindrance to the acquisition of high quality immunofluorescence images is endogenous autofluorescence of the tissue caused by aging pigments such as lipofuscin or by common sample preparation processes such as aldehyde fixation. This protocol describes how background fluorescence can be greatly reduced through photobleaching using white phosphor light emitting diode (LED) arrays prior to treatment with fluorescent probes. The broad-spectrum emission of white phosphor LEDs allow for bleaching of fluorophores across a range of emission peaks. The photobleaching apparatus can be constructed from off-the-shelf components at very low cost and offers an accessible alternative to commercially available chemical quenchers. A photobleaching pre-treatment of the tissue followed by conventional immunofluorescence staining generates images free of background autofluorescence. Compared to established chemical quenchers which reduced probe as well as background signals, photobleaching treatment had no effect on probe fluorescence intensity while it effectively reduced background and lipofuscin fluorescence. Although photobleaching requires more time for pre-treatment, higher intensity LED arrays may be used to reduce photobleaching time. This simple method can potentially be applied to a variety of tissues, particularly postmitotic tissues that accumulate lipofuscin such as the brain and cardiac or skeletal muscles.

  4. Study of robot landmark recognition with complex background

    NASA Astrophysics Data System (ADS)

    Huang, Yuqing; Yang, Jia

    2007-12-01

    It's of great importance for assisting robot in path planning, position navigating and task performing by perceiving and recognising environment characteristic. To solve the problem of monocular-vision-oriented landmark recognition for mobile intelligent robot marching with complex background, a kind of nested region growing algorithm which fused with transcendental color information and based on current maximum convergence center is proposed, allowing invariance localization to changes in position, scale, rotation, jitters and weather conditions. Firstly, a novel experiment threshold based on RGB vision model is used for the first image segmentation, which allowing some objects and partial scenes with similar color to landmarks also are detected with landmarks together. Secondly, with current maximum convergence center on segmented image as each growing seed point, the above region growing algorithm accordingly starts to establish several Regions of Interest (ROI) orderly. According to shape characteristics, a quick and effectual contour analysis based on primitive element is applied in deciding whether current ROI could be reserved or deleted after each region growing, then each ROI is judged initially and positioned. When the position information as feedback is conveyed to the gray image, the whole landmarks are extracted accurately with the second segmentation on the local image that exclusive to landmark area. Finally, landmarks are recognised by Hopfield neural network. Results issued from experiments on a great number of images with both campus and urban district as background show the effectiveness of the proposed algorithm.

  5. Academic information on Twitter: A user survey.

    PubMed

    Mohammadi, Ehsan; Thelwall, Mike; Kwasny, Mary; Holmes, Kristi L

    2018-01-01

    Although counts of tweets citing academic papers are used as an informal indicator of interest, little is known about who tweets academic papers and who uses Twitter to find scholarly information. Without knowing this, it is difficult to draw useful conclusions from a publication being frequently tweeted. This study surveyed 1,912 users that have tweeted journal articles to ask about their scholarly-related Twitter uses. Almost half of the respondents (45%) did not work in academia, despite the sample probably being biased towards academics. Twitter was used most by people with a social science or humanities background. People tend to leverage social ties on Twitter to find information rather than searching for relevant tweets. Twitter is used in academia to acquire and share real-time information and to develop connections with others. Motivations for using Twitter vary by discipline, occupation, and employment sector, but not much by gender. These factors also influence the sharing of different types of academic information. This study provides evidence that Twitter plays a significant role in the discovery of scholarly information and cross-disciplinary knowledge spreading. Most importantly, the large numbers of non-academic users support the claims of those using tweet counts as evidence for the non-academic impacts of scholarly research.

  6. Academic information on Twitter: A user survey

    PubMed Central

    Thelwall, Mike; Kwasny, Mary; Holmes, Kristi L.

    2018-01-01

    Although counts of tweets citing academic papers are used as an informal indicator of interest, little is known about who tweets academic papers and who uses Twitter to find scholarly information. Without knowing this, it is difficult to draw useful conclusions from a publication being frequently tweeted. This study surveyed 1,912 users that have tweeted journal articles to ask about their scholarly-related Twitter uses. Almost half of the respondents (45%) did not work in academia, despite the sample probably being biased towards academics. Twitter was used most by people with a social science or humanities background. People tend to leverage social ties on Twitter to find information rather than searching for relevant tweets. Twitter is used in academia to acquire and share real-time information and to develop connections with others. Motivations for using Twitter vary by discipline, occupation, and employment sector, but not much by gender. These factors also influence the sharing of different types of academic information. This study provides evidence that Twitter plays a significant role in the discovery of scholarly information and cross-disciplinary knowledge spreading. Most importantly, the large numbers of non-academic users support the claims of those using tweet counts as evidence for the non-academic impacts of scholarly research. PMID:29771947

  7. Adaptive removal of background and white space from document images using seam categorization

    NASA Astrophysics Data System (ADS)

    Fillion, Claude; Fan, Zhigang; Monga, Vishal

    2011-03-01

    Document images are obtained regularly by rasterization of document content and as scans of printed documents. Resizing via background and white space removal is often desired for better consumption of these images, whether on displays or in print. While white space and background are easy to identify in images, existing methods such as naïve removal and content aware resizing (seam carving) each have limitations that can lead to undesirable artifacts, such as uneven spacing between lines of text or poor arrangement of content. An adaptive method based on image content is hence needed. In this paper we propose an adaptive method to intelligently remove white space and background content from document images. Document images are different from pictorial images in structure. They typically contain objects (text letters, pictures and graphics) separated by uniform background, which include both white paper space and other uniform color background. Pixels in uniform background regions are excellent candidates for deletion if resizing is required, as they introduce less change in document content and style, compared with deletion of object pixels. We propose a background deletion method that exploits both local and global context. The method aims to retain the document structural information and image quality.

  8. US Forest Service and National Park Service Wilderness Aircraft Overflight Study: Sociological background and study plans

    NASA Technical Reports Server (NTRS)

    Harrison, Robin T.; Hartmann, Lawrence

    1990-01-01

    The background and sociological aspects of the combined U.S. Forest Service and National Park Service Wilderness Aircraft Overflight Study (WACOS) are presented. The WACOS broaches a new area of research by combining aspects of outdoor recreation sociology and aircraft noise response studies. The tasks faced create new challenges and require innovative solutions. Background information on the WACOS is presented with special emphasis on sociological considerations. At the time of this writing, no data have yet been collected, so this paper will present background information, related issues, and plans for data collection. Some recent studies indicate that managers of Forest Service wildernesses and National Park Service areas consider aircraft overflights to be a problem to their users in some areas. Additional relevant background research from outdoor recreation sociology is discussed, followed by presentation of the authors' opinions of the most salient sociological issues faced by this study. The goals and desired end products are identified next, followed by a review of the methods anticipated to be used to obtain these results. Finally, a discussion and conclusion section is provided.

  9. Influence of background/surrounding area on accuracy of visual color matching.

    PubMed

    Dudea, Diana; Gasparik, Cristina; Botos, Alexandra; Alb, Florin; Irimie, Ada; Paravina, Rade D

    2016-07-01

    Visual shade selection is subjective and influenced by factors that might be operator-dependent or not. The objective was to evaluate influence of observer nonrelated factors (background/surrounding area, and light) and observer-related factors (gender and color competence) on shade-matching quality and to identify the most often mismatched shades in correlation with the background. Ten observers with average or superior color discrimination competence according to ISO TR 28642:2011 were asked to match 48 shade tabs of three VITA Classical shade guides, in a viewing booth under two light sources: D65 and D50. Gray, white, black, red, and light blue background/surrounding area simulated various clinical situations. The results were statistically analyzed using Kruskal-Wallis test and Mann-Whitney U test. Post hoc power analyses and sample size calculations were also conducted. The matching scores ranged between 72.7 % (using blue background) and 85.9 % (using white and black backgrounds). There was a statistically significant difference between matching scores on the five backgrounds (χ (2)(4) = 12.67, p = 0.01). When neutral gray was used as reference, Mann-Whitney U value was statistically significant only for the blue background (U = 107.00, Z = -2.52, p = 0.01). The influence of gender and lighting condition was also assessed, no statistically significance being found, but in both cases, the effect size and the achieved power were small. However, color discrimination competence did influence the results (p < 0.01). Background influenced shade matching results for tabs A3, B3, B4, and D4. Within the limitations of this study, it was concluded that 1. When it comes to the influence of the background/surround area on quality of color matching, no difference among achromatic backgrounds was recorded. Significantly worse results were recorded when the blue background was used. 2. Observers with superior color matching competence performed

  10. The Conterminous United States Mineral Appraisal Program; background information to accompany folio of geologic, geochemical, geophysical, and mineral resources maps of the Medford 1 degree x 2 degrees Quadrangle, Oregon and California

    USGS Publications Warehouse

    Smith, James G.; Blakely, R.J.; Johnson, M.G.; Page, N.J.; Peterson, J.A.; Singer, D.A.; Whittington, C.L.

    1986-01-01

    The Medford 1 ? by 2 ? quadrangle in southern Oregon and northern California was studied by an interdisciplinary research team to appraise its mineral resources. The appraisal is based on geological, geochemical, and geophysical field and laboratory investigations, the results of which are published as a folio of maps, figures, and tables, with accompanying discussions. This circular provides background information on the investigations and integrates the information presented in the folio. The bibliography lists selected references to the geology, geochemistry, geophysics, and mineral deposits of the Medford 1 ? by 2 ? quadrangle.

  11. The National Comorbidity Survey Adolescent Supplement (NCS-A): I. Background and Measures

    PubMed Central

    Merikangas, Kathleen R.; Avenevoli, Shelli; Costello, E. Jane; Koretz, Doreen; Kessler, Ronald C.

    2009-01-01

    Objective This paper presents an overview of the background and measures used in the National Comorbidity Survey Replication Adolescent Supplement (NCS-A). Methods The NCS-A is a national psychiatric epidemiological survey of adolescents ages 13–17. Results The NCS-A was designed to provide the first nationally representative estimates of the prevalence, correlates and patterns of service use for DSM-V mental disorders among US adolescents and to lay the groundwork for follow-up studies of risk-protective factors, consequences, and early expressions of adult mental disorders. The core NCS-A diagnostic interview, the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI), is a fully-structured research diagnostic interview designed for use by trained lay interviewers. A multi-construct, multi-method, multi-informant battery was also included to assess risk and protective factors and barriers to service use. Design limitations due to the NCS-A evolving as a supplement to an ongoing survey of mental disorders of US adults include restricted age range of youth, cross-sectional assessment, and lack of full parental/surrogate informant reports on youth mental disorders and correlates. Conclusions Despite these limitations, the NCS-A contains unparalleled information that can be used to generate national estimates of prevalence and correlates of adolescent mental disorders, risk and protective factors, patterns of service use, and barriers to receiving treatment for these disorders. The retrospective NCS-A data on the development of psychopathology can additionally complement data from longitudinal studies based on more geographically restricted samples and serve as a useful baseline for future prospective studies of the onset and progression of mental disorders in adulthood. PMID:19242382

  12. Studies of the extreme ultraviolet/soft x-ray background

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stern, R.A.

    1978-01-01

    The results of an extensive sky survey of the extreme ultraviolet (EUV)/soft x-ray background are reported. The data were obtained with a focusing telescope designed and calibrated at U.C. Berkeley which observed EUV sources and the diffuse background as part of the Apollo-Soyuz mission in July, 1975. With a primary field-of-view of 2.3 + 0.1/sup 0/ FWHM and four EUV bandpass filters (16 to 25, 20 to 73, 80 to 108, and 80 to 250 eV) the EUV telescope obtained background data included in the final observational sample for 21 discrete sky locations and 11 large angular scans, as wellmore » as for a number of shorter observations. Analysis of the data reveals as intense flux above 80 eV energy, with upper limits to the background intensity given for the lower energy filters Ca 2 x 10/sup 4/ and 6 x 10/sup 2/ ph cm/sup -2/ sec/sup -1/ ster/sup -1/ eV/sup -1/ at 21 and 45 eV respectively). The 80 to 108 eV flux agrees within statistical errors with the earlier results of Cash, Malina and Stern (1976): the Apollo-Soyuz average reported intensity is 4.0 +- 1.3 ph cm/sup -2/ sec/sup -1/ ster/sup -1/ eV/sup -1/ at Ca 100 eV, or roughly a factor of ten higher than the corresponding 250 eV intensity. The uniformity of the background flux is uncertain due to limitations in the statistical accuracy of the data; upper limits to the point-to-point standard deviation of the background intensity are (..delta..I/I approximately less than 0.8 +- 0.4 (80 to 108 eV) and approximately less than 0.4 +- 0.2 (80 to 250 eV). No evidence is found for a correlation between the telescope count rate and earth-based parameters (zenith angle, sun angle, etc.) for E approximately greater than 80 eV (the lower energy bandpasses are significantly affected by scattered solar radiation. Unlike some previous claims for the soft x-ray background, no simple dependence upon galactic latitude is seen.« less

  13. Unexpected effects of different genetic backgrounds on identification of genomic rearrangements via whole-genome next generation sequencing.

    PubMed

    Chen, Zhangguo; Gowan, Katherine; Leach, Sonia M; Viboolsittiseri, Sawanee S; Mishra, Ameet K; Kadoishi, Tanya; Diener, Katrina; Gao, Bifeng; Jones, Kenneth; Wang, Jing H

    2016-10-21

    Whole genome next generation sequencing (NGS) is increasingly employed to detect genomic rearrangements in cancer genomes, especially in lymphoid malignancies. We recently established a unique mouse model by specifically deleting a key non-homologous end-joining DNA repair gene, Xrcc4, and a cell cycle checkpoint gene, Trp53, in germinal center B cells. This mouse model spontaneously develops mature B cell lymphomas (termed G1XP lymphomas). Here, we attempt to employ whole genome NGS to identify novel structural rearrangements, in particular inter-chromosomal translocations (CTXs), in these G1XP lymphomas. We sequenced six lymphoma samples, aligned our NGS data with mouse reference genome (in C57BL/6J (B6) background) and identified CTXs using CREST algorithm. Surprisingly, we detected widespread CTXs in both lymphomas and wildtype control samples, majority of which were false positive and attributable to different genetic backgrounds. In addition, we validated our NGS pipeline by sequencing multiple control samples from distinct tissues of different genetic backgrounds of mouse (B6 vs non-B6). Lastly, our studies showed that widespread false positive CTXs can be generated by simply aligning sequences from different genetic backgrounds of mouse. We conclude that mapping and alignment with reference genome might not be a preferred method for analyzing whole-genome NGS data obtained from a genetic background different from reference genome. Given the complex genetic background of different mouse strains or the heterogeneity of cancer genomes in human patients, in order to minimize such systematic artifacts and uncover novel CTXs, a preferred method might be de novo assembly of personalized normal control genome and cancer cell genome, instead of mapping and aligning NGS data to mouse or human reference genome. Thus, our studies have critical impact on the manner of data analysis for cancer genomics.

  14. CTEPP NC DATA SUPPLEMENTAL INFORMATION ON FIELD AND LABORATORY SAMPLES

    EPA Science Inventory

    This data set contains supplemental data related to the final core analytical results table. This includes sample collection data for example sample weight, air volume, creatinine, specific gravity etc.

    The Children’s Total Exposure to Persistent Pesticides and Other Persistent...

  15. Sensitivity enhancement and contrasting information provided by free radicals in oriented-sample NMR of bicelle-reconstituted membrane proteins.

    PubMed

    Tesch, Deanna M; Nevzorov, Alexander A

    2014-02-01

    Elucidating structure and topology of membrane proteins (MPs) is essential for unveiling functionality of these important biological constituents. Oriented-sample solid-state NMR (OS-NMR) is capable of providing such information on MPs under nearly physiological conditions. However, two dimensional OS-NMR experiments can take several days to complete due to long longitudinal relaxation times combined with the large number of scans to achieve sufficient signal sensitivity in biological samples. Here, free radicals 5-DOXYL stearic acid, TEMPOL, and CAT-1 were added to uniformly (15)N-labeled Pf1 coat protein reconstituted in DMPC/DHPC bicelles, and their effect on the longitudinal relaxation times (T1Z) was investigated. The dramatically shortened T1Z's allowed for the signal gain per unit time to be used for either: (i) up to a threefold reduction of the total experimental time at 99% magnetization recovery or (ii) obtaining up to 74% signal enhancement between the control and radical samples during constant experimental time at "optimal" relaxation delays. In addition, through OS-NMR and high-field EPR studies, free radicals were able to provide positional constraints in the bicelle system, which provide a description of the location of each residue in Pf1 coat protein within the bicellar membranes. This information can be useful in the determination of oligomerization states and immersion depths of larger membrane proteins. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Ethnic identity and the academic adjustment of adolescents from Mexican, Chinese, and European backgrounds.

    PubMed

    Fuligni, Andrew J; Witkow, Melissa; Garcia, Carla

    2005-09-01

    The association of adolescents' ethnic identification with their academic attitudes and achievement was examined among a sample of 589 ninth-grade students from Mexican, Chinese, and European backgrounds. Adolescents from all backgrounds chose a variety of ethnic labels to describe themselves, with those from Mexican, Chinese, and immigrant families incorporating more of their families' national origin and cultural background into their chosen ethnic labels. Nevertheless, the strength of adolescents' ethnic identification was more relevant to their academic adjustment than the specific labels that they chose, and it was most important for the extra motivation necessary for ethnic minority students to attain the same level of academic success as their European American peers. Copyright 2005 APA, all rights reserved.

  17. CTEPP-OH DATA SUPPLEMENTAL INFORMATION ON FIELD AND LABORATORY SAMPLES

    EPA Science Inventory

    This data set contains supplemental data related to the final core analytical results table for CTEPP-OH. This includes sample collection data for example sample weight, air volume, creatinine, specific gravity etc.

    The Children’s Total Exposure to Persistent Pesticides and Oth...

  18. Carbon-13 Isotopic Abundance and Concentration of Atmospheric Methane for Background Air in the Southern and Northern Hemispheres from 1978 to 1989 (NDP-049)

    DOE Data Explorer

    Stevens, C. M. [Chemical Technology Division, Argonne National Laboratory, Argonne, Illinois (USA)

    2012-01-01

    This data package presents atmospheric CH4 concentration and 13C isotopic abundance data derived from air samples collected over the period 1978-1989 at globally distributed clean-air sites. The data set comprises 201 records, 166 from the Northern Hemisphere and 35 from the Southern Hemisphere. The air samples were collected mostly in rural or marine locations remote from large sources of CH4 and are considered representative of tropospheric background conditions. The air samples were processed by isolation of CH4 from air and conversion to CO2 for isotopic analysis by isotope ratio mass spectrometry. These data represent one of the earliest records of 13C isotopic yy!measurements for atmospheric methane and have been used to refine estimates of CH4 emissions, calculate annual growth rates of emissions from changing sources, and provide evidence for changes in the rate of atmospheric removal of CH4. The data records consist of sample collection date; number of samples combined for analysis; sampling location; analysis date; CH4 concentration; 13C isotopic abundance; and flag codes to indicate outliers, repeated analyses, and other information.

  19. Dilatonic parallelizable NS-NS backgrounds

    NASA Astrophysics Data System (ADS)

    Kawano, Teruhiko; Yamaguchi, Satoshi

    2003-08-01

    We complete the classification of parallelizable NS-NS backgrounds in type II supergravity by adding the dilatonic case to the result of Figueroa-O'Farrill on the non-dilatonic case. We also study the supersymmetry of these parallelizable backgrounds. It is shown that all the dilatonic parallelizable backgrounds have sixteen supersymmetries.

  20. The Joint Effects of Background Selection and Genetic Recombination on Local Gene Genealogies

    PubMed Central

    Zeng, Kai; Charlesworth, Brian

    2011-01-01

    Background selection, the effects of the continual removal of deleterious mutations by natural selection on variability at linked sites, is potentially a major determinant of DNA sequence variability. However, the joint effects of background selection and genetic recombination on the shape of the neutral gene genealogy have proved hard to study analytically. The only existing formula concerns the mean coalescent time for a pair of alleles, making it difficult to assess the importance of background selection from genome-wide data on sequence polymorphism. Here we develop a structured coalescent model of background selection with recombination and implement it in a computer program that efficiently generates neutral gene genealogies for an arbitrary sample size. We check the validity of the structured coalescent model against forward-in-time simulations and show that it accurately captures the effects of background selection. The model produces more accurate predictions of the mean coalescent time than the existing formula and supports the conclusion that the effect of background selection is greater in the interior of a deleterious region than at its boundaries. The level of linkage disequilibrium between sites is elevated by background selection, to an extent that is well summarized by a change in effective population size. The structured coalescent model is readily extendable to more realistic situations and should prove useful for analyzing genome-wide polymorphism data. PMID:21705759

  1. The joint effects of background selection and genetic recombination on local gene genealogies.

    PubMed

    Zeng, Kai; Charlesworth, Brian

    2011-09-01

    Background selection, the effects of the continual removal of deleterious mutations by natural selection on variability at linked sites, is potentially a major determinant of DNA sequence variability. However, the joint effects of background selection and genetic recombination on the shape of the neutral gene genealogy have proved hard to study analytically. The only existing formula concerns the mean coalescent time for a pair of alleles, making it difficult to assess the importance of background selection from genome-wide data on sequence polymorphism. Here we develop a structured coalescent model of background selection with recombination and implement it in a computer program that efficiently generates neutral gene genealogies for an arbitrary sample size. We check the validity of the structured coalescent model against forward-in-time simulations and show that it accurately captures the effects of background selection. The model produces more accurate predictions of the mean coalescent time than the existing formula and supports the conclusion that the effect of background selection is greater in the interior of a deleterious region than at its boundaries. The level of linkage disequilibrium between sites is elevated by background selection, to an extent that is well summarized by a change in effective population size. The structured coalescent model is readily extendable to more realistic situations and should prove useful for analyzing genome-wide polymorphism data.

  2. Differential Relations between Facets of Complex Problem Solving and Students' Immigration Background

    ERIC Educational Resources Information Center

    Sonnleitner, Philipp; Brunner, Martin; Keller, Ulrich; Martin, Romain

    2014-01-01

    Whereas the assessment of complex problem solving (CPS) has received increasing attention in the context of international large-scale assessments, its fairness in regard to students' cultural background has gone largely unexplored. On the basis of a student sample of 9th-graders (N = 299), including a representative number of immigrant students (N…

  3. Interdisciplinary Research and Information Overload.

    ERIC Educational Resources Information Center

    Wilson, Patrick

    1996-01-01

    Discusses information overload and examines several ways in which actual and potential overload affects research choices for the solo researcher in interdisciplinary areas. Topics include information overload and teamwork; entry barriers to certain specialties, including necessary background knowledge; and information utilization and knowledge…

  4. Background Information for Think Tank on Planning, Governance and System Building Early Care and Education--NYC

    ERIC Educational Resources Information Center

    Boressoff, Todd

    2008-01-01

    This document provides some background on early childhood planning and system building around the country. Since mid-December, the author has been studying these efforts for Child Care, Inc. (CCI) interviewing national experts and reading widely. This outline provides insights and lesson learned from those inquiries. The goal at this meeting will…

  5. Probability Sampling Method for a Hidden Population Using Respondent-Driven Sampling: Simulation for Cancer Survivors.

    PubMed

    Jung, Minsoo

    2015-01-01

    When there is no sampling frame within a certain group or the group is concerned that making its population public would bring social stigma, we say the population is hidden. It is difficult to approach this kind of population survey-methodologically because the response rate is low and its members are not quite honest with their responses when probability sampling is used. The only alternative known to address the problems caused by previous methods such as snowball sampling is respondent-driven sampling (RDS), which was developed by Heckathorn and his colleagues. RDS is based on a Markov chain, and uses the social network information of the respondent. This characteristic allows for probability sampling when we survey a hidden population. We verified through computer simulation whether RDS can be used on a hidden population of cancer survivors. According to the simulation results of this thesis, the chain-referral sampling of RDS tends to minimize as the sample gets bigger, and it becomes stabilized as the wave progresses. Therefore, it shows that the final sample information can be completely independent from the initial seeds if a certain level of sample size is secured even if the initial seeds were selected through convenient sampling. Thus, RDS can be considered as an alternative which can improve upon both key informant sampling and ethnographic surveys, and it needs to be utilized for various cases domestically as well.

  6. Amino acid analyses of Apollo 14 samples.

    NASA Technical Reports Server (NTRS)

    Gehrke, C. W.; Zumwalt, R. W.; Kuo, K.; Aue, W. A.; Stalling, D. L.; Kvenvolden, K. A.; Ponnamperuma, C.

    1972-01-01

    Detection limits were between 300 pg and 1 ng for different amino acids, in an analysis by gas-liquid chromatography of water extracts from Apollo 14 lunar fines in which amino acids were converted to their N-trifluoro-acetyl-n-butyl esters. Initial analyses of water and HCl extracts of sample 14240 and 14298 samples showed no amino acids above background levels.

  7. Information Resources; A Searcher's Manual. MOREL Regional Information System for Educators.

    ERIC Educational Resources Information Center

    Grimes, George; Doyle, James

    This document is one of a series describing the background, functions, and utilization of the Regional Information System (RIS) developed by the Michigan-Ohio Regional Educational Laboratory (MOREL). The purpose of this manual is to detail a procedure for performing a productive search of information resources which can satisfy the informational…

  8. Extracting Optical Fiber Background from Surface-Enhanced Raman Spectroscopy Spectra Based on Bi-Objective Optimization Modeling.

    PubMed

    Huang, Jie; Shi, Tielin; Tang, Zirong; Zhu, Wei; Liao, Guanglan; Li, Xiaoping; Gong, Bo; Zhou, Tengyuan

    2017-08-01

    We propose a bi-objective optimization model for extracting optical fiber background from the measured surface-enhanced Raman spectroscopy (SERS) spectrum of the target sample in the application of fiber optic SERS. The model is built using curve fitting to resolve the SERS spectrum into several individual bands, and simultaneously matching some resolved bands with the measured background spectrum. The Pearson correlation coefficient is selected as the similarity index and its maximum value is pursued during the spectral matching process. An algorithm is proposed, programmed, and demonstrated successfully in extracting optical fiber background or fluorescence background from the measured SERS spectra of rhodamine 6G (R6G) and crystal violet (CV). The proposed model not only can be applied to remove optical fiber background or fluorescence background for SERS spectra, but also can be transferred to conventional Raman spectra recorded using fiber optic instrumentation.

  9. Estimation of background radiation doses for the Peninsular Malaysia's population by ESR dosimetry of tooth enamel.

    PubMed

    Rodzi, Mohd; Zhumadilov, Kassym; Ohtaki, Megu; Ivannikov, Alexander; Bhattacharjee, Deborshi; Fukumura, Akifumi; Hoshi, Masaharu

    2011-08-01

    Background radiation dose is used in dosimetry for estimating occupational doses of radiation workers or determining radiation dose of an individual following accidental exposure. In the present study, the absorbed dose and the background radiation level are determined using the electron spin resonance (ESR) method on tooth samples. The effect of using different tooth surfaces and teeth exposed with single medical X-rays on the absorbed dose are also evaluated. A total of 48 molars of position 6-8 were collected from 13 district hospitals in Peninsular Malaysia. Thirty-six teeth had not been exposed to any excessive radiation, and 12 teeth had been directly exposed to a single X-ray dose during medical treatment prior to extraction. There was no significant effect of tooth surfaces and exposure with single X-rays on the measured absorbed dose of an individual. The mean measured absorbed dose of the population is 34 ± 6.2 mGy, with an average tooth enamel age of 39 years. From the slope of a regression line, the estimated annual background dose for Peninsular Malaysia is 0.6 ± 0.3 mGy y(-1). This value is slightly lower than the yearly background dose for Malaysia, and the radiation background dose is established by ESR tooth measurements on samples from India and Russia.

  10. Developing Water Sampling Standards

    ERIC Educational Resources Information Center

    Environmental Science and Technology, 1974

    1974-01-01

    Participants in the D-19 symposium on aquatic sampling and measurement for water pollution assessment were informed that determining the extent of waste water stream pollution is not a cut and dry procedure. Topics discussed include field sampling, representative sampling from storm sewers, suggested sampler features and application of improved…

  11. Financial Information Source, Knowledge, and Practices of College Students from Diverse Backgrounds

    ERIC Educational Resources Information Center

    Mimura, Yoko; Koonce, Joan; Plunkett, Scott W.; Pleskus, Lindsey

    2015-01-01

    Using cross-sectional data, we examined the financial information sources, financial knowledge, and financial practices of young adults, many of whom are first generation college students, ethnic minorities, and immigrants or children of immigrants. Participants (n = 1,249) were undergraduate students at a large regional comprehensive university.…

  12. Developing Students' Reasoning about Samples and Sampling in the Context of Informal Inferences

    ERIC Educational Resources Information Center

    Meletiou-Mavrotheris, Maria; Paparistodemou, Efi

    2015-01-01

    The expanding use of data in modern society for prediction and decision-making makes it a priority for mathematics instruction to help students build sound foundations of inferential reasoning at a young age. This study contributes to the emerging research literature on the early development of informal inferential reasoning through the conduct of…

  13. A Background Study of Negro College Students. Bulletin, 1933, No. 8

    ERIC Educational Resources Information Center

    Caliver, Ambrose

    1933-01-01

    This bulletin presents a fundamental study of the social backgrounds of college freshmen in 33 colleges for Negro youth located in 17 states. The purpose of this study is to establish criteria and reveal trends with which local schools may compare their own student bodies; and to furnish a body of information which will be helpful in establishing…

  14. Factors affecting implementation of perinatal mental health screening in women of refugee background.

    PubMed

    Nithianandan, Nishani; Gibson-Helm, Melanie; McBride, Jacquie; Binny, Amanda; Gray, Kylie M; East, Christine; Boyle, Jacqueline A

    2016-11-18

    For women of refugee background, the increased risk of mental illness associated with pregnancy is compounded by pre- and post-settlement stressors. In Australia, antenatal screening for depression and anxiety symptoms using the Edinburgh Postnatal Depression Scale is recommended for all women. Despite this, screening is not routinely implemented and little is known about barriers and enablers to implementation for women of refugee background. Semi-structured interviews were conducted with a range of health professionals (n = 28: midwives, obstetricians, perinatal mental health and refugee health experts, interpreters) and women of refugee background (n = 9). Themes generated from thematic analysis were examined in relation to the Theoretical Domains Framework and Cultural Competence Conceptual Framework, followed by identification of effective behaviour change techniques to address the barriers and enablers identified by participants. These techniques formed the basis of recommendations to inform sustainable implementation of screening and referral. Almost all participants perceived perinatal mental health screening to be necessary and most recognised the importance of post-traumatic stress disorder (PTSD) screening. Barriers and enablers were identified and related to eight domains: knowledge, skills, professional roles, beliefs about capabilities and consequences, environmental context, social influences and behavioural regulation. This research clarifies how mental health screening may be integrated into routine antenatal care for women of refugee background, in order to improve provision of recommended care. These theory-informed recommendations include an inter-disciplinary approach, coordinating care within and across services, addition of PTSD screening, and effective communication with women.

  15. Gamma-ray Background Spectrum and Annihilation Rate in the Baryon-symmetric Big-bang Cosmology

    NASA Technical Reports Server (NTRS)

    Puget, J. L.

    1973-01-01

    An attempt was made to acquire experimental information on the problem of baryon symmetry on a large cosmological scale by observing the annihilation products. Data cover absorption cross sections and background radiation due to other sources for the two main products of annihilation, gamma rays and neutrinos. Test results show that the best direct experimental test for the presence of large scale antimatter lies in the gamma ray background spectrum between 1 and 70 MeV.

  16. Stressful Life Events in a Clinical Sample of Depressed Children in Hungary

    PubMed Central

    Mayer, László; Lopez-Duran, Nestor L.; Kovacs, Maria; George, Charles; Baji, Ildikó; Kapornai, Krisztina; Kiss, Enikő; Vetró, Ágnes

    2009-01-01

    Background There is limited information on the characteristics of stressful life events in depressed pediatric clinical populations and the extent to which sex, age, and their interactions may influence the relations of life events and depression. Using a very large clinical sample of children and adolescents with major depressive disorder (MDD), we therefore examined life events in various ways as well as their relations to age and sex. Method The study included a clinic-based sample of 434 children (ages 7–14) with a DSM-IV diagnosis of MDD and their mothers, and a school-based comparison sample of 724 children and their mothers. Life event information was obtained from the mothers. Results Children with MDD had twice the number of lifetime stressful events than did the comparison group, with very high levels of stressors by the age of 7–9 that stabilized across adolescence. In contrast, the comparison sample experienced a gradual increase in stressful life events as a function of age up to mid-adolescence. Parental health events, death of close relatives, and intra-familial events were significantly associated with MDD diagnosis. There were significantly stronger associations between parental health- as well as death-event clusters and MDD diagnosis among younger children than adolescents. Limitations Geographical differences between the clinical and comparison samples, as well as possible parental reporting biases may affect the generalizability of these findings. Conclusion The association between some stressful life events and MDD seems to be moderated by age, underscoring the need to examine specific events, as well as clusters of events. Better understanding of such interactions may facilitate early identification of possible risk factors for pediatric MDD. PMID:18845343

  17. Improving informed consent: Stakeholder views

    PubMed Central

    Anderson, Emily E.; Newman, Susan B.; Matthews, Alicia K.

    2017-01-01

    Purpose Innovation will be required to improve the informed consent process in research. We aimed to obtain input from key stakeholders—research participants and those responsible for obtaining informed consent—to inform potential development of a multimedia informed consent “app.” Methods This descriptive study used a mixed-methods approach. Five 90-minute focus groups were conducted with volunteer samples of former research participants and researchers/research staff responsible for obtaining informed consent. Participants also completed a brief survey that measured background information and knowledge and attitudes regarding research and the use of technology. Established qualitative methods were used to conduct the focus groups and data analysis. Results We conducted five focus groups with 41 total participants: three groups with former research participants (total n = 22), and two groups with researchers and research coordinators (total n = 19). Overall, individuals who had previously participated in research had positive views regarding their experiences. However, further discussion elicited that the informed consent process often did not meet its intended objectives. Findings from both groups are presented according to three primary themes: content of consent forms, experience of the informed consent process, and the potential of technology to improve the informed consent process. A fourth theme, need for lay input on informed consent, emerged from the researcher groups. Conclusions Our findings add to previous research that suggests that the use of interactive technology has the potential to improve the process of informed consent. However, our focus-group findings provide additional insight that technology cannot replace the human connection that is central to the informed consent process. More research that incorporates the views of key stakeholders is needed to ensure that multimedia consent processes do not repeat the mistakes of paper

  18. Improving informed consent: Stakeholder views.

    PubMed

    Anderson, Emily E; Newman, Susan B; Matthews, Alicia K

    2017-01-01

    Innovation will be required to improve the informed consent process in research. We aimed to obtain input from key stakeholders-research participants and those responsible for obtaining informed consent-to inform potential development of a multimedia informed consent "app." This descriptive study used a mixed-methods approach. Five 90-minute focus groups were conducted with volunteer samples of former research participants and researchers/research staff responsible for obtaining informed consent. Participants also completed a brief survey that measured background information and knowledge and attitudes regarding research and the use of technology. Established qualitative methods were used to conduct the focus groups and data analysis. We conducted five focus groups with 41 total participants: three groups with former research participants (total n = 22), and two groups with researchers and research coordinators (total n = 19). Overall, individuals who had previously participated in research had positive views regarding their experiences. However, further discussion elicited that the informed consent process often did not meet its intended objectives. Findings from both groups are presented according to three primary themes: content of consent forms, experience of the informed consent process, and the potential of technology to improve the informed consent process. A fourth theme, need for lay input on informed consent, emerged from the researcher groups. Our findings add to previous research that suggests that the use of interactive technology has the potential to improve the process of informed consent. However, our focus-group findings provide additional insight that technology cannot replace the human connection that is central to the informed consent process. More research that incorporates the views of key stakeholders is needed to ensure that multimedia consent processes do not repeat the mistakes of paper-based consent forms.

  19. Characterizing spatiotemporal information loss in sparse-sampling-based dynamic MRI for monitoring respiration-induced tumor motion in radiotherapy.

    PubMed

    Arai, Tatsuya J; Nofiele, Joris; Madhuranthakam, Ananth J; Yuan, Qing; Pedrosa, Ivan; Chopra, Rajiv; Sawant, Amit

    2016-06-01

    Sparse-sampling and reconstruction techniques represent an attractive strategy to achieve faster image acquisition speeds, while maintaining adequate spatial resolution and signal-to-noise ratio in rapid magnetic resonance imaging (MRI). The authors investigate the use of one such sequence, broad-use linear acquisition speed-up technique (k-t BLAST) in monitoring tumor motion for thoracic and abdominal radiotherapy and examine the potential trade-off between increased sparsification (to increase imaging speed) and the potential loss of "true" information due to greater reliance on a priori information. Lung tumor motion trajectories in the superior-inferior direction, previously recorded from ten lung cancer patients, were replayed using a motion phantom module driven by an MRI-compatible motion platform. Eppendorf test tubes filled with water which serve as fiducial markers were placed in the phantom. The modeled rigid and deformable motions were collected in a coronal image slice using balanced fast field echo in conjunction with k-t BLAST. Root mean square (RMS) error was used as a metric of spatial accuracy as measured trajectories were compared to input data. The loss of spatial information was characterized for progressively increasing acceleration factor from 1 to 16; the resultant sampling frequency was increased approximately from 2.5 to 19 Hz when the principal direction of the motion was set along frequency encoding direction. In addition to the phantom study, respiration-induced tumor motions were captured from two patients (kidney tumor and lung tumor) at 13 Hz over 49 s to demonstrate the impact of high speed motion monitoring over multiple breathing cycles. For each subject, the authors compared the tumor centroid trajectory as well as the deformable motion during free breathing. In the rigid and deformable phantom studies, the RMS error of target tracking at the acquisition speed of 19 Hz was approximately 0.3-0.4 mm, which was smaller than the

  20. Creativity, information, and consciousness: The information dynamics of thinking.

    PubMed

    Wiggins, Geraint A

    2018-05-07

    This paper presents a theory of the basic operation of mind, Information Dynamics of Thinking, which is intended for computational implementation and thence empirical testing. It is based on the information theory of Shannon, and treats the mind/brain as an information processing organ that aims to be information-efficient, in that it predicts its world, so as to use information efficiently, and regularly re-represents it, so as to store information efficiently. The theory is presented in context of a background review of various research areas that impinge upon its development. Consequences of the theory and testable hypotheses arising from it are discussed. Copyright © 2018. Published by Elsevier B.V.

  1. Subsurface Noble Gas Sampling Manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carrigan, C. R.; Sun, Y.

    2017-09-18

    The intent of this document is to provide information about best available approaches for performing subsurface soil gas sampling during an On Site Inspection or OSI. This information is based on field sampling experiments, computer simulations and data from the NA-22 Noble Gas Signature Experiment Test Bed at the Nevada Nuclear Security Site (NNSS). The approaches should optimize the gas concentration from the subsurface cavity or chimney regime while simultaneously minimizing the potential for atmospheric radioxenon and near-surface Argon-37 contamination. Where possible, we quantitatively assess differences in sampling practices for the same sets of environmental conditions. We recognize that allmore » sampling scenarios cannot be addressed. However, if this document helps to inform the intuition of the reader about addressing the challenges resulting from the inevitable deviations from the scenario assumed here, it will have achieved its goal.« less

  2. Multidrug Resistance among New Tuberculosis Cases: Detecting Local Variation through Lot Quality-Assurance Sampling

    PubMed Central

    Lynn Hedt, Bethany; van Leth, Frank; Zignol, Matteo; Cobelens, Frank; van Gemert, Wayne; Viet Nhung, Nguyen; Lyepshina, Svitlana; Egwaga, Saidi; Cohen, Ted

    2012-01-01

    Background Current methodology for multidrug-resistant TB (MDR TB) surveys endorsed by the World Health Organization provides estimates of MDR TB prevalence among new cases at the national level. On the aggregate, local variation in the burden of MDR TB may be masked. This paper investigates the utility of applying lot quality-assurance sampling to identify geographic heterogeneity in the proportion of new cases with multidrug resistance. Methods We simulated the performance of lot quality-assurance sampling by applying these classification-based approaches to data collected in the most recent TB drug-resistance surveys in Ukraine, Vietnam, and Tanzania. We explored three classification systems—two-way static, three-way static, and three-way truncated sequential sampling—at two sets of thresholds: low MDR TB = 2%, high MDR TB = 10%, and low MDR TB = 5%, high MDR TB = 20%. Results The lot quality-assurance sampling systems identified local variability in the prevalence of multidrug resistance in both high-resistance (Ukraine) and low-resistance settings (Vietnam). In Tanzania, prevalence was uniformly low, and the lot quality-assurance sampling approach did not reveal variability. The three-way classification systems provide additional information, but sample sizes may not be obtainable in some settings. New rapid drug-sensitivity testing methods may allow truncated sequential sampling designs and early stopping within static designs, producing even greater efficiency gains. Conclusions Lot quality-assurance sampling study designs may offer an efficient approach for collecting critical information on local variability in the burden of multidrug-resistant TB. Before this methodology is adopted, programs must determine appropriate classification thresholds, the most useful classification system, and appropriate weighting if unbiased national estimates are also desired. PMID:22249242

  3. Time of flight spectrometer for background-free positron annihilation induced Auger electron spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukherjee, S.; Shastry, K.; Anto, C. V.

    2016-03-15

    We describe a novel spectrometer designed for positron annihilation induced Auger electron spectroscopy employing a time-of-flight spectrometer. The spectrometer’s new configuration enables us to implant monoenergetic positrons with kinetic energies as low as 1.5 eV on the sample while simultaneously allowing for the detection of electrons emitted from the sample surface at kinetic energies ranging from ∼500 eV to 0 eV. The spectrometer’s unique characteristics made it possible to perform (a) first experiments demonstrating the direct transition of a positron from an unbound scattering state to a bound surface state and (b) the first experiments demonstrating that Auger electron spectramore » can be obtained down to 0 eV without the beam induced secondary electron background obscuring the low energy part of the spectra. Data are presented which show alternative means of estimating positron surface state binding energy and background-free Auger spectra.« less

  4. Enhancing Earth Science And IT Literacy Through Environmental Science Information Technology Activities

    NASA Astrophysics Data System (ADS)

    Cuff, K. E.; Molinaro, M.

    2004-12-01

    The Environmental Science Information Technology Activities (ESITA) program provides grades 9 and 10 students with under-represented minority backgrounds in the East San Francisco Bay Area with real-world opportunities to learn about and apply information technologies through a series of project-based activities related to environmental science. Supported by the NSF Information Technology Experiences for Students and Teachers (ITEST) program, ESITA activities engage students in the use of newly acquired information technology (IT) skills and understandings while performing air and water quality research investigations. One project that ESITA students have become involved in relates to the currently relevant issue of elevated levels of lead found in drinking waters in Washington, D.C. Students based in the Bay Area have initiated and maintained E-mail correspondence with children who attend elementary schools in the D.C. area. After receiving a thorough explanation of required sampling procedures devised by the Bay Area students, the elementary school children have sent 500 ml water samples from their homes and schools to Berkeley along with information about the locations from which the water samples were collected. These samples were then prepared for lead analysis at Lawrence Hall of Science by ESITA students, who used resulting data to perform a preliminary assessment of the geospatial distribution of lead trouble spots throughout Washington, DC. Later, ESITA student scientists will work with students from the UC Berkeley School of Public Health to develop surveys and questionnaires that generate high quality information useful with regard to assessing the impact of the current lead crisis on younger children in the Washington, D.C. area. Through the application of new understandings to current, real-world environmental problems and issues such as that related to lead, positive changes in students' attitudes towards IT and science have occurred, which accompany

  5. Efficient Monte Carlo Estimation of the Expected Value of Sample Information Using Moment Matching.

    PubMed

    Heath, Anna; Manolopoulou, Ioanna; Baio, Gianluca

    2018-02-01

    The Expected Value of Sample Information (EVSI) is used to calculate the economic value of a new research strategy. Although this value would be important to both researchers and funders, there are very few practical applications of the EVSI. This is due to computational difficulties associated with calculating the EVSI in practical health economic models using nested simulations. We present an approximation method for the EVSI that is framed in a Bayesian setting and is based on estimating the distribution of the posterior mean of the incremental net benefit across all possible future samples, known as the distribution of the preposterior mean. Specifically, this distribution is estimated using moment matching coupled with simulations that are available for probabilistic sensitivity analysis, which is typically mandatory in health economic evaluations. This novel approximation method is applied to a health economic model that has previously been used to assess the performance of other EVSI estimators and accurately estimates the EVSI. The computational time for this method is competitive with other methods. We have developed a new calculation method for the EVSI which is computationally efficient and accurate. This novel method relies on some additional simulation so can be expensive in models with a large computational cost.

  6. A literature survey of information on well installation and sample collection procedures used in investigations of ground-water contamination by organic compounds

    USGS Publications Warehouse

    Dumouchelle, D.H.; Lynch, E.A.; Cummings, T.R.

    1990-01-01

    A survey of literature on well installation and water-quality sampling, particularly as they relate to investigations of ground-water contamination by organic compounds, has been conducted. Library card files and computerized data bases were searched to identify journal articles, conference proceedings, technical reports, books, and other publications. Pertinent information has been extracted from 105 references; each reference is listed in a bibliography. Material contained in the report is organized by topical categories that include drilling methods and equipment, well construction, well development, sampling materials and equipment, decontamination of equipment, and sampling techniques and procedures. Unpublished data of the U.S. Geological Survey on sample collection are briefly cited also.

  7. Botanical Dietary Supplements: Background Information

    MedlinePlus

    Skip navigation links U.S. Department of Health & Human Services HHS.gov National Institutes of Health NIH.gov Font Size Decrease Font Size Increase Font Size Strengthening Knowledge and Understanding of ...

  8. X-Ray Computed Tomography: The First Step in Mars Sample Return Processing

    NASA Technical Reports Server (NTRS)

    Welzenbach, L. C.; Fries, M. D.; Grady, M. M.; Greenwood, R. C.; McCubbin, F. M.; Zeigler, R. A.; Smith, C. L.; Steele, A.

    2017-01-01

    The Mars 2020 rover mission will collect and cache samples from the martian surface for possible retrieval and subsequent return to Earth. If the samples are returned, that mission would likely present an opportunity to analyze returned Mars samples within a geologic context on Mars. In addition, it may provide definitive information about the existence of past or present life on Mars. Mars sample return presents unique challenges for the collection, containment, transport, curation and processing of samples [1] Foremost in the processing of returned samples are the closely paired considerations of life detection and Planetary Protection. In order to achieve Mars Sample Return (MSR) science goals, reliable analyses will depend on overcoming some challenging signal/noise-related issues where sparse martian organic compounds must be reliably analyzed against the contamination background. While reliable analyses will depend on initial clean acquisition and robust documentation of all aspects of developing and managing the cache [2], there needs to be a reliable sample handling and analysis procedure that accounts for a variety of materials which may or may not contain evidence of past or present martian life. A recent report [3] suggests that a defined set of measurements should be made to effectively inform both science and Planetary Protection, when applied in the context of the two competing null hypotheses: 1) that there is no detectable life in the samples; or 2) that there is martian life in the samples. The defined measurements would include a phased approach that would be accepted by the community to preserve the bulk of the material, but provide unambiguous science data that can be used and interpreted by various disciplines. Fore-most is the concern that the initial steps would ensure the pristine nature of the samples. Preliminary, non-invasive techniques such as computed X-ray tomography (XCT) have been suggested as the first method to interrogate and

  9. The Conterminous United States Mineral Appraisal Program; background information to accompany folio of geologic, geochemical, geophysical, and mineral resources maps of the Walker Lake 1 degree x 2 degrees Quadrangle, California and Nevada

    USGS Publications Warehouse

    Stewart, John Harris; Chaffee, M.A.; Dohrenwend, J.C.; John, D.A.; Kistler, R.W.; Kleinhampl, F.J.; Menzie, W.D.; Plouff, Donald; Rowan, L.C.; Silberling, Norman J.

    1984-01-01

    The Walker Lake 1? by 2? quadrangle in eastern California and western Nevada was studied by an interdisciplinary research team to appraise its mineral resources. The appraisal is based on geological, geochemical, and geophysical field and laboratory investigations, the results of which are published as a folio of maps, figures, and tables, with accompanying discussions. This circular provides background information on the investigations and integrates the information presented in the folio. The selected bibliography lists selected references to the geology, geochemistry, geophysics, and mineral deposits of the Walker Lake 1? by 2? quadrangle.

  10. Downselection for Sample Return — Defining Sampling Strategies Using Lessons from Terrestrial Field Analogues

    NASA Astrophysics Data System (ADS)

    Stevens, A. H.; Gentry, D.; Amador, E.; Cable, M. L.; Cantrell, T.; Chaudry, N.; Cullen, T.; Duca, Z.; Jacobsen, M.; Kirby, J.; McCaig, H.; Murukesan, G.; Rader, E.; Rennie, V.; Schwieterman, E.; Sutton, S.; Tan, G.; Yin, C.; Cullen, D.; Geppert, W.; Stockton, A.

    2018-04-01

    We detail multi-year field investigations in Icelandic Mars analogue environments that have yielded results that can help inform strategies for sample selection and downselection for Mars Sample Return.

  11. Unsupervised background-constrained tank segmentation of infrared images in complex background based on the Otsu method.

    PubMed

    Zhou, Yulong; Gao, Min; Fang, Dan; Zhang, Baoquan

    2016-01-01

    In an effort to implement fast and effective tank segmentation from infrared images in complex background, the threshold of the maximum between-class variance method (i.e., the Otsu method) is analyzed and the working mechanism of the Otsu method is discussed. Subsequently, a fast and effective method for tank segmentation from infrared images in complex background is proposed based on the Otsu method via constraining the complex background of the image. Considering the complexity of background, the original image is firstly divided into three classes of target region, middle background and lower background via maximizing the sum of their between-class variances. Then, the unsupervised background constraint is implemented based on the within-class variance of target region and hence the original image can be simplified. Finally, the Otsu method is applied to simplified image for threshold selection. Experimental results on a variety of tank infrared images (880 × 480 pixels) in complex background demonstrate that the proposed method enjoys better segmentation performance and even could be comparative with the manual segmentation in segmented results. In addition, its average running time is only 9.22 ms, implying the new method with good performance in real time processing.

  12. Preschool Teachers' Professional Background, Process Quality, and Job Attitudes: A Person-Centered Approach

    ERIC Educational Resources Information Center

    Jeon, Lieny; Buettner, Cynthia K.; Hur, Eunhye

    2016-01-01

    Research Findings: This exploratory study identified preschool teacher quality profiles in early childhood education settings using 9 indicators across teachers' professional background, observed process quality, and job attitudes toward teaching (e.g., job-related stress, satisfaction, and intention to leave the job). The sample consisted of 96…

  13. C3: The Compositional Construction of Context. A New, More Effective and Efficient Way to Marshal Inferences from Background Knowledge

    DTIC Science & Technology

    2014-09-01

    quarter. Deep natural language understanding , efficient inference, pragmatics, background knowledge U U U SAR 4 Dr. David McDonald (781) 718-1964 C3...effective and efficient way to marshal inferences from background knowledge ’ N00014-13-1-0228 Dr. David McDonald Smart Information Flow Technologies, dba...for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data

  14. MixHMM: Inferring Copy Number Variation and Allelic Imbalance Using SNP Arrays and Tumor Samples Mixed with Stromal Cells

    PubMed Central

    Schulz, Vincent; Chen, Min; Tuck, David

    2010-01-01

    Background Genotyping platforms such as single nucleotide polymorphism (SNP) arrays are powerful tools to study genomic aberrations in cancer samples. Allele specific information from SNP arrays provides valuable information for interpreting copy number variation (CNV) and allelic imbalance including loss-of-heterozygosity (LOH) beyond that obtained from the total DNA signal available from array comparative genomic hybridization (aCGH) platforms. Several algorithms based on hidden Markov models (HMMs) have been designed to detect copy number changes and copy-neutral LOH making use of the allele information on SNP arrays. However heterogeneity in clinical samples, due to stromal contamination and somatic alterations, complicates analysis and interpretation of these data. Methods We have developed MixHMM, a novel hidden Markov model using hidden states based on chromosomal structural aberrations. MixHMM allows CNV detection for copy numbers up to 7 and allows more complete and accurate description of other forms of allelic imbalance, such as increased copy number LOH or imbalanced amplifications. MixHMM also incorporates a novel sample mixing model that allows detection of tumor CNV events in heterogeneous tumor samples, where cancer cells are mixed with a proportion of stromal cells. Conclusions We validate MixHMM and demonstrate its advantages with simulated samples, clinical tumor samples and a dilution series of mixed samples. We have shown that the CNVs of cancer cells in a tumor sample contaminated with up to 80% of stromal cells can be detected accurately using Illumina BeadChip and MixHMM. Availability The MixHMM is available as a Python package provided with some other useful tools at http://genecube.med.yale.edu:8080/MixHMM. PMID:20532221

  15. Trace Element Analysis of Biological Samples.

    ERIC Educational Resources Information Center

    Veillon, Claude

    1986-01-01

    Reviews background of atomic absorption spectrometry techniques. Discusses problems encountered and precautions to be taken in determining trace elements in the parts-per-billion concentration range and below. Concentrates on determining chromium in biological samples by graphite furnace atomic absorption. Considers other elements, matrices, and…

  16. Developing Written Information for Cancer Survivors from Culturally and Linguistically Diverse Backgrounds: Lessons Learnt.

    PubMed

    Wiley, Georgina; Piper, Amanda; Phyllis Butow, A M; Schofield, Penny; Douglas, Fiona; Roy, Jane; Nolte, Linda; Jefford, Michael

    2018-01-01

    Australia is a multicultural nation with a large migrant population. Migrants with cancer report inferior quality of life and the need for more information in their own language. This paper describes lessons learnt from developing culturally appropriate written information resources with and for Arabic, Italian, and Vietnamese cancer survivors and carers. The information needs of survivors from these language groups as well as guidelines for the development of written resources for culturally diverse populations were identified through literature review. Community consultation was undertaken with focus groups. The content was developed and tested with health professionals who spoke the appropriate language and focus group participants, ensuring relevance and appropriateness. Resource design and dissemination were informed through community consultation. A number of key tasks for developing resources were identified as follows: (1) community engagement and consultation; (2) culturally sensitive data collection; (3) focus group facilitators (recruitment and training); (4) content development; (5) translation and review process; (6) design; and (7) sustainability. This project reinforced literature review findings on the importance of cultural sensitivity in the development of resources. Engaging with community groups and incorporating culturally appropriate recruitment strategies optimises recruitment to focus groups and facilitates content development. Stakeholders and lay persons from the intended ethnic-minority communities should be involved in the development and formative evaluation of resources to ensure appropriateness and relevance and in the dissemination strategy to optimize penetration. We believe the lessons we have learnt will be relevant to any group intending to develop health information for culturally and linguistic diverse groups.

  17. Developing Written Information for Cancer Survivors from Culturally and Linguistically Diverse Backgrounds: Lessons Learnt

    PubMed Central

    Wiley, Georgina; Piper, Amanda; Phyllis Butow, AM; Schofield, Penny; Douglas, Fiona; Roy, Jane; Nolte, Linda; Jefford, Michael

    2018-01-01

    Australia is a multicultural nation with a large migrant population. Migrants with cancer report inferior quality of life and the need for more information in their own language. This paper describes lessons learnt from developing culturally appropriate written information resources with and for Arabic, Italian, and Vietnamese cancer survivors and carers. The information needs of survivors from these language groups as well as guidelines for the development of written resources for culturally diverse populations were identified through literature review. Community consultation was undertaken with focus groups. The content was developed and tested with health professionals who spoke the appropriate language and focus group participants, ensuring relevance and appropriateness. Resource design and dissemination were informed through community consultation. A number of key tasks for developing resources were identified as follows: (1) community engagement and consultation; (2) culturally sensitive data collection; (3) focus group facilitators (recruitment and training); (4) content development; (5) translation and review process; (6) design; and (7) sustainability. This project reinforced literature review findings on the importance of cultural sensitivity in the development of resources. Engaging with community groups and incorporating culturally appropriate recruitment strategies optimises recruitment to focus groups and facilitates content development. Stakeholders and lay persons from the intended ethnic-minority communities should be involved in the development and formative evaluation of resources to ensure appropriateness and relevance and in the dissemination strategy to optimize penetration. We believe the lessons we have learnt will be relevant to any group intending to develop health information for culturally and linguistic diverse groups. PMID:29379844

  18. Across North America tracer experiment (ANATEX): Sampling and analysis

    NASA Astrophysics Data System (ADS)

    Draxler, R. R.; Dietz, R.; Lagomarsino, R. J.; Start, G.

    Between 5 January 1987 and 29 March 1987, there were 33 releases of different tracers from each of two sites: Glasgow, MT and St. Cloud, MN. The perfluorocarbon tracers were routinely released in a 3-h period every 2.5 days, alternating between daytime and night-time tracer releases. Ground-level air samples of 24-h duration were taken at 77 sites mostly located near rawinsonde stations east of 105°W and between 26°N and 55°N. Weekly air samples were taken at 12 remote sites between San Diego, CA and Pt. Barrow, AK and between Norway and the Canary Islands. Short-term 6-h samples were collected at ground level and 200 m AGL along an arc of five towers between Tulsa, OK and Green Bay, WI. Aircraft sampling within several hundred kilometers of both tracer release sites was used to establish the initial tracer path. Experimental design required improved sampler performance, new tracers with lower atmospheric backgrounds, and improvements in analytic precision. The advances to the perfluorocarbon tracer system are discussed in detail. Results from the tracer sampling showed that the average and peak concentrations measured over the daily ground-level sampling network were consistent with what would be calculated using mass conservative approaches. however, ground-level samples from individual tracer patterns showed considerable complexity due to vertical stability or the interaction of the tracer plumes with low pressure and frontal systems. These systems could pass right through the tracer plume without appreciable effect. Aircraft tracer measurements are used to confirm the initial tracer trajectory when the narrow plume may miss the coarser spaced ground-level sampling network. Tower tracer measurements showed a more complex temporal structure than evident from the longer duration ground-level sampling sites. Few above background plume measurements were evident in the more distant remote sampling network due to larger than expected uncertainties in the ambient

  19. Does family background impact driving attitudes and risky behaviours? An investigation on Chinese young drivers.

    PubMed

    Wang, Zhe; Zheng, Zuduo; Fleiter, Judy J

    2016-10-01

    The rapid pace of motorisation in China has been well documented, as has the large road trauma burden the Chinese citizens are facing as a result. China's unique political system represents an important consideration in helping reduce road trauma, yet political factors have not been previously investigated in this context. Recently, emerging issues on the road involving the adult children of politically powerful families have become a serious social problem in China, and have drawn widespread media and public attention. This study took a novel approach to examining factors associated with risky attitudes and risky road use in China by investigating the economic and political background status of a sample of young Chinese drivers. An online survey was conducted in May 2015 with a sample size of 476 Chinese young drivers from across the country, aged between 18 and 28, including 305 males and 171 females. The results suggest that for participants who reported having a familial political background, more risky driving behaviours were reported among those participants who reported more impact on their life from that political background; while for participants without political background, higher personal income was associated with more risky driving behaviours. The findings are discussed in light of China's political management system and potential education opportunities for young drivers. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. A sample of potential disk hosting first ascent red giants

    NASA Astrophysics Data System (ADS)

    Steele, Amy; Debes, John

    2018-01-01

    Observations of (sub)giants with planets and disks provide the first set of proof that disks can survive the first stages of post-main-sequence evolution, even though the disks are expected to dissipate by this time. The infrared (IR) excesses present around a number of post-main-sequence (PMS) stars could be due to a traditional debris disk with planets (e.g. kappa CrB), some remnant of enhanced mass loss (e.g. the shell-like structure of R Sculptoris), and/or background contamination. We present a sample of potential disk hosting first ascent red giants. These stars all have infrared excesses at 22 microns, and possibly host circumstellar debris. We summarize the characteristics of the sample to better inform the incidence rates of thermally emitting material around giant stars. A thorough follow-up study of these candidates would serve as the first step in probing the composition of the dust in these systems that have left the main sequence, providing clues to the degree of disk processing that occurs beyond the main-sequence.