Science.gov

Sample records for base published search

  1. Radon gas: Health risks and toxicity. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-03-01

    The bibliography contains citations concerning the potential health risks associated with indoor and outdoor exposure to radon gas. Included are sources such as cigarette smoke, fossil fuel combustion, phosphate mining, uranium mining, granitic rocks, building materials, and water supplies. Citations include toxicology studies, risk assessment studies, exposure modeling, exposure pathways, physiological effects, and exposure control. Radionuclides in groundwater, and radon analysis and detection, are presented in separate Published Searches. (Contains a minimum of 129 citations and includes a subject term index and title list.)

  2. Quality of search strategies reported in systematic reviews published in stereotactic radiosurgery.

    PubMed

    Faggion, Clovis M; Wu, Yun-Chun; Tu, Yu-Kang; Wasiak, Jason

    2016-06-01

    Systematic reviews require comprehensive literature search strategies to avoid publication bias. This study aimed to assess and evaluate the reporting quality of search strategies within systematic reviews published in the field of stereotactic radiosurgery (SRS). Three electronic databases (Ovid MEDLINE(®), Ovid EMBASE(®) and the Cochrane Library) were searched to identify systematic reviews addressing SRS interventions, with the last search performed in October 2014. Manual searches of the reference lists of included systematic reviews were conducted. The search strategies of the included systematic reviews were assessed using a standardized nine-question form based on the Cochrane Collaboration guidelines and Assessment of Multiple Systematic Reviews checklist. Multiple linear regression analyses were performed to identify the important predictors of search quality. A total of 85 systematic reviews were included. The median quality score of search strategies was 2 (interquartile range = 2). Whilst 89% of systematic reviews reported the use of search terms, only 14% of systematic reviews reported searching the grey literature. Multiple linear regression analyses identified publication year (continuous variable), meta-analysis performance and journal impact factor (continuous variable) as predictors of higher mean quality scores. This study identified the urgent need to improve the quality of search strategies within systematic reviews published in the field of SRS. This study is the first to address how authors performed searches to select clinical studies for inclusion in their systematic reviews. Comprehensive and well-implemented search strategies are pivotal to reduce the chance of publication bias and consequently generate more reliable systematic review findings.

  3. Discovering ecologically relevant knowledge from published studies through geosemantic searching

    USDA-ARS?s Scientific Manuscript database

    It is easier to search the globe for research on genes of a local plant or animal than to find local field research on that plant’s ecology. While internet applications can find the closest coffee shop, it is difficult to find where the nearest relevant research was conducted. As a result, ecologi...

  4. Do published search filters to identify diagnostic test accuracy studies perform adequately?

    PubMed

    Ritchie, Gill; Glanville, Julie; Lefebvre, Carol

    2007-09-01

    To assess the performance of published search filters in finding diagnostic test accuracy studies. Diagnostic test accuracy search filters were identified by searching medline, our own files and by requesting unpublished filters from colleagues. We applied the filters to a case study review of diagnostic test accuracy studies for urinary tract infections (UTI) in young children. The included studies with records in medline formed the gold standard. The performance of the filters in finding those gold standard records was assessed. We identified twenty-three diagnostic test accuracy search filters for use with medline. The case study systematic review of UTI included 179 studies of diagnostic test accuracy, of which 160 were available in medline. The filters showed a wide range of sensitivities (range: 20.6% to 86.9%) and precision (range: 1% to 9.4%). Our results broadly support those reported in two other studies. The search filters tested do not offer an adequate trade-off between sensitivity and precision to be used to identify studies for systematic reviews. However, there are methods available to explore whether search filters are viable based on an objective statistical analysis of the text and indexing used in records.

  5. Developing a search engine for pharmacotherapeutic information that is not published in biomedical journals.

    PubMed

    Do Pazo-Oubiña, F; Calvo Pita, C; Puigventós Latorre, F; Periañez-Párraga, L; Ventayol Bosch, P

    2011-01-01

    To identify publishers of pharmacotherapeutic information not found in biomedical journals that focuses on evaluating and providing advice on medicines and to develop a search engine to access this information. Compiling web sites that publish information on the rational use of medicines and have no commercial interests. Free-access web sites in Spanish, Galician, Catalan or English. Designing a search engine using the Google "custom search" application. Overall 159 internet addresses were compiled and were classified into 9 labels. We were able to recover the information from the selected sources using a search engine, which is called "AlquimiA" and available from http://www.elcomprimido.com/FARHSD/AlquimiA.htm. The main sources of pharmacotherapeutic information not published in biomedical journals were identified. The search engine is a useful tool for searching and accessing "grey literature" on the internet. Copyright © 2010 SEFH. Published by Elsevier Espana. All rights reserved.

  6. Intelligent buildings. (Latest citations from the INSPEC database). Published Search

    SciTech Connect

    1996-12-01

    The bibliography contains citations concerning concepts, design, and development of intelligent buildings. Citations discuss building management systems, including centralized control systems for air conditioning, space heating, fire prevention, building security, power supply systems, and telecommunication. Knowledge-based systems and expert systems for use in intelligent building design are included. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  7. Search-based optimization.

    PubMed

    Wheeler, Ward C

    2003-08-01

    The problem of determining the minimum cost hypothetical ancestral sequences for a given cladogram is known to be NP-complete (Wang and Jiang, 1994). Traditionally, point estimations of hypothetical ancestral sequences have been used to gain heuristic, upper bounds on cladogram cost. These include procedures with such diverse approaches as non-additive optimization of multiple sequence alignment, direct optimization (Wheeler, 1996), and fixed-state character optimization (Wheeler, 1999). A method is proposed here which, by extending fixed-state character optimization, replaces the estimation process with a search. This form of optimization examines a diversity of potential state solutions for cost-efficient hypothetical ancestral sequences and can result in greatly more parsimonious cladograms. Additionally, such an approach can be applied to other NP-complete phylogenetic optimization problems such as genomic break-point analysis. c2003 The Willi Hennig Society. Published by Elsevier Science (USA). All rights reserved.

  8. Search-based optimization

    NASA Technical Reports Server (NTRS)

    Wheeler, Ward C.

    2003-01-01

    The problem of determining the minimum cost hypothetical ancestral sequences for a given cladogram is known to be NP-complete (Wang and Jiang, 1994). Traditionally, point estimations of hypothetical ancestral sequences have been used to gain heuristic, upper bounds on cladogram cost. These include procedures with such diverse approaches as non-additive optimization of multiple sequence alignment, direct optimization (Wheeler, 1996), and fixed-state character optimization (Wheeler, 1999). A method is proposed here which, by extending fixed-state character optimization, replaces the estimation process with a search. This form of optimization examines a diversity of potential state solutions for cost-efficient hypothetical ancestral sequences and can result in greatly more parsimonious cladograms. Additionally, such an approach can be applied to other NP-complete phylogenetic optimization problems such as genomic break-point analysis. c2003 The Willi Hennig Society. Published by Elsevier Science (USA). All rights reserved.

  9. Search-based optimization

    NASA Technical Reports Server (NTRS)

    Wheeler, Ward C.

    2003-01-01

    The problem of determining the minimum cost hypothetical ancestral sequences for a given cladogram is known to be NP-complete (Wang and Jiang, 1994). Traditionally, point estimations of hypothetical ancestral sequences have been used to gain heuristic, upper bounds on cladogram cost. These include procedures with such diverse approaches as non-additive optimization of multiple sequence alignment, direct optimization (Wheeler, 1996), and fixed-state character optimization (Wheeler, 1999). A method is proposed here which, by extending fixed-state character optimization, replaces the estimation process with a search. This form of optimization examines a diversity of potential state solutions for cost-efficient hypothetical ancestral sequences and can result in greatly more parsimonious cladograms. Additionally, such an approach can be applied to other NP-complete phylogenetic optimization problems such as genomic break-point analysis. c2003 The Willi Hennig Society. Published by Elsevier Science (USA). All rights reserved.

  10. MEDLINE clinical queries are robust when searching in recent publishing years

    PubMed Central

    Wilczynski, Nancy L; McKibbon, K Ann; Walter, Stephen D; Garg, Amit X; Haynes, R Brian

    2013-01-01

    Objective To determine if the PubMed and Ovid MEDLINE clinical queries (which were developed in the publishing year 2000, for the purpose categories therapy, diagnosis, prognosis, etiology, and clinical prediction guides) perform as well when searching in current publishing years. Methods A gold standard database of recently published research literature was created using the McMaster health knowledge refinery (http://hiru.mcmaster.ca/hiru/HIRU_McMaster_HKR.aspx) and its continuously updated database, McMaster PLUS (http://hiru.mcmaster.ca/hiru/HIRU_McMaster_PLUS_projects.aspx). This database contains articles from over 120 clinical journals that are tagged for meeting or not meeting criteria for scientific merit and clinical relevance. The clinical queries sensitive (‘broad’) and specific (‘narrow’) search filters were tested in this gold standard database, and sensitivity and specificity were calculated and compared with those originally reported for the clinical queries. Results In all cases, the sensitivity of the highly sensitive search filters and the specificity of the highly specific search filters did not differ substantively when comparing results derived in 2000 with those derived in a more current database. In addition, in all cases, the specificities for the highly sensitive search filters and the sensitivities for the highly specific search filters remained above 50% when testing them in the current database. Discussion These results are reassuring for modern-day searchers. The clinical queries that were derived in the year 2000 perform equally well a decade later. Conclusion The PubMed and Ovid MEDLINE clinical queries have been revalidated and remain a useful public resource for searching the world's medical literature for research that is most relevant to clinical care. PMID:23019242

  11. MEDLINE clinical queries are robust when searching in recent publishing years.

    PubMed

    Wilczynski, Nancy L; McKibbon, K Ann; Walter, Stephen D; Garg, Amit X; Haynes, R Brian

    2013-01-01

    To determine if the PubMed and Ovid MEDLINE clinical queries (which were developed in the publishing year 2000, for the purpose categories therapy, diagnosis, prognosis, etiology, and clinical prediction guides) perform as well when searching in current publishing years. A gold standard database of recently published research literature was created using the McMaster health knowledge refinery (http://hiru.mcmaster.ca/hiru/HIRU_McMaster_HKR.aspx) and its continuously updated database, McMaster PLUS (http://hiru.mcmaster.ca/hiru/HIRU_McMaster_PLUS_projects.aspx). This database contains articles from over 120 clinical journals that are tagged for meeting or not meeting criteria for scientific merit and clinical relevance. The clinical queries sensitive ('broad') and specific ('narrow') search filters were tested in this gold standard database, and sensitivity and specificity were calculated and compared with those originally reported for the clinical queries. In all cases, the sensitivity of the highly sensitive search filters and the specificity of the highly specific search filters did not differ substantively when comparing results derived in 2000 with those derived in a more current database. In addition, in all cases, the specificities for the highly sensitive search filters and the sensitivities for the highly specific search filters remained above 50% when testing them in the current database. These results are reassuring for modern-day searchers. The clinical queries that were derived in the year 2000 perform equally well a decade later. The PubMed and Ovid MEDLINE clinical queries have been revalidated and remain a useful public resource for searching the world's medical literature for research that is most relevant to clinical care.

  12. Location-based Web Search

    NASA Astrophysics Data System (ADS)

    Ahlers, Dirk; Boll, Susanne

    In recent years, the relation of Web information to a physical location has gained much attention. However, Web content today often carries only an implicit relation to a location. In this chapter, we present a novel location-based search engine that automatically derives spatial context from unstructured Web resources and allows for location-based search: our focused crawler applies heuristics to crawl and analyze Web pages that have a high probability of carrying a spatial relation to a certain region or place; the location extractor identifies the actual location information from the pages; our indexer assigns a geo-context to the pages and makes them available for a later spatial Web search. We illustrate the usage of our spatial Web search for location-based applications that provide information not only right-in-time but also right-on-the-spot.

  13. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1996-10-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  14. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1995-09-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  15. Chemical and biological warfare: General studies. (Latest citations from the NTIS Bibliographic database). Published Search

    SciTech Connect

    Not Available

    1993-11-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 250 citations and includes a subject term index and title list.)

  16. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1997-11-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  17. Systematic Reviews Published in Emergency Medicine Journals Do Not Routinely Search Clinical Trials Registries: A Cross-Sectional Analysis.

    PubMed

    Keil, Lukas G; Platts-Mills, Timothy F; Jones, Christopher W

    2015-10-01

    Publication bias compromises the validity of systematic reviews. This problem can be addressed in part through searching clinical trials registries to identify unpublished studies. This study aims to determine how often systematic reviews published in emergency medicine journals include clinical trials registry searches. We identified all systematic reviews published in the 6 highest-impact emergency medicine journals between January 1 and December 31, 2013. Systematic reviews that assessed the effects of an intervention were further examined to determine whether the authors described searching a clinical trials registry and whether this search identified relevant unpublished studies. Of 191 articles identified through PubMed search, 80 were confirmed to be systematic reviews. Our sample consisted of 41 systematic reviews that assessed a specific intervention. Eight of these 41 (20%) searched a clinical trials registry. For 4 of these 8 reviews, the registry search identified at least 1 relevant unpublished study. Systematic reviews published in emergency medicine journals do not routinely include searches of clinical trials registries. By helping authors identify unpublished trial data, the addition of registry searches may improve the validity of systematic reviews. Copyright © 2014 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

  18. OneSearch Gives You Access to More Than 7,000 Publishers and Content Providers | Poster

    Cancer.gov

    By Robin Meckley, Contributing Writer OneSearch, an exciting new resource from the Scientific Library, is now available to the NCI at Frederick community. This new resource provides a quick and easy way to search multiple Scientific Library resources and collections using a single search box for journal articles, books, media, and more. A large central index is compiled from more than 7,000 publishers and content providers outside the library’s holdings.

  19. OneSearch Gives You Access to More Than 7,000 Publishers and Content Providers | Poster

    Cancer.gov

    By Robin Meckley, Contributing Writer OneSearch, an exciting new resource from the Scientific Library, is now available to the NCI at Frederick community. This new resource provides a quick and easy way to search multiple Scientific Library resources and collections using a single search box for journal articles, books, media, and more. A large central index is compiled from more than 7,000 publishers and content providers outside the library’s holdings.

  20. Task-Based Information Searching.

    ERIC Educational Resources Information Center

    Vakkari, Pertti

    2003-01-01

    Reviews studies on the relationship between task performance and information searching by end-users, focusing on information searching in electronic environments and information retrieval systems. Topics include task analysis; task characteristics; search goals; modeling information searching; modeling search goals; information seeking behavior;…

  1. Distributed search engine architecture based on topic specific searches

    NASA Astrophysics Data System (ADS)

    Abudaqqa, Yousra; Patel, Ahmed

    2015-05-01

    Indisputably, search engines (SEs) abound. The monumental growth of users performing online searches on the Web is a contending issue in the contemporary world nowadays. For example, there are tens of billions of searches performed everyday, which typically offer the users many irrelevant results which are time consuming and costly to the user. Based on the afore-going problem it has become a herculean task for existing Web SEs to provide complete, relevant and up-to-date information response to users' search queries. To overcome this problem, we developed the Distributed Search Engine Architecture (DSEA), which is a new means of smart information query and retrieval of the World Wide Web (WWW). In DSEAs, multiple autonomous search engines, owned by different organizations or individuals, cooperate and act as a single search engine. This paper includes the work reported in this research focusing on development of DSEA, based on topic-specific specialised search engines. In DSEA, the results to specific queries could be provided by any of the participating search engines, for which the user is unaware of. The important design goal of using topic-specific search engines in the research is to build systems that can effectively be used by larger number of users simultaneously. Efficient and effective usage with good response is important, because it involves leveraging the vast amount of searched data from the World Wide Web, by categorising it into condensed focused topic -specific results that meet the user's queries. This design model and the development of the DSEA adopt a Service Directory (SD) to route queries towards topic-specific document hosting SEs. It displays the most acceptable performance which is consistent with the requirements of the users. The evaluation results of the model return a very high priority score which is associated with each frequency of a keyword.

  2. Pump turbines. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning pump turbines with emphasis on pumped storage. Design, development, testing, operational evaluation, and problem areas are included. Many of the abstracts reference reports on flow characteristics, including draft tube surges, dynamic loads and forces vibration, cavitation, and starting problems. Both the pumping mode and the turbine (generating) mode, for analyses of speed rise, overpressure, overspeed, and general flow investigations are examined. (Contains 250 citations and includes a subject term index and title list.)

  3. Publishing Support for Small Print-Based Publishers: Options for ARL Libraries

    ERIC Educational Resources Information Center

    Ivins, October; Luther, Judy

    2011-01-01

    This project was originally defined to explore the potential for ARL libraries to provide support to small, print-only publishers in order to ensure long-term digital access to their content. Research library publishing programs vary widely, from posting PDFs in an institutional repository to full-fledged publishing operations. During the life of…

  4. A Quantitative Analysis of Published Skull Base Endoscopy Literature.

    PubMed

    Hardesty, Douglas A; Ponce, Francisco A; Little, Andrew S; Nakaji, Peter

    2016-02-01

    Objectives Skull base endoscopy allows for minimal access approaches to the sinonasal contents and cranial base. Advances in endoscopic technique and applications have been published rapidly in recent decades. Setting We utilized an Internet-based scholarly database (Web of Science, Thomson Reuters) to query broad-based phrases regarding skull base endoscopy literature. Participants All skull base endoscopy publications. Main Outcome Measures Standard bibliometrics outcomes. Results We identified 4,082 relevant skull base endoscopy English-language articles published between 1973 and 2014. The 50 top-cited publications (n = 51, due to articles with equal citation counts) ranged in citation count from 397 to 88. Most of the articles were clinical case series or technique descriptions. Most (96% [49/51])were published in journals specific to either neurosurgery or otolaryngology. Conclusions A relatively small number of institutions and individuals have published a large amount of the literature. Most of the publications consisted of case series and technical advances, with a lack of randomized trials.

  5. A Quantitative Analysis of Published Skull Base Endoscopy Literature

    PubMed Central

    Hardesty, Douglas A.; Ponce, Francisco A.; Little, Andrew S.; Nakaji, Peter

    2015-01-01

    Objectives Skull base endoscopy allows for minimal access approaches to the sinonasal contents and cranial base. Advances in endoscopic technique and applications have been published rapidly in recent decades. Setting We utilized an Internet-based scholarly database (Web of Science, Thomson Reuters) to query broad-based phrases regarding skull base endoscopy literature. Participants All skull base endoscopy publications. Main Outcome Measures Standard bibliometrics outcomes. Results We identified 4,082 relevant skull base endoscopy English-language articles published between 1973 and 2014. The 50 top-cited publications (n = 51, due to articles with equal citation counts) ranged in citation count from 397 to 88. Most of the articles were clinical case series or technique descriptions. Most (96% [49/51])were published in journals specific to either neurosurgery or otolaryngology. Conclusions A relatively small number of institutions and individuals have published a large amount of the literature. Most of the publications consisted of case series and technical advances, with a lack of randomized trials. PMID:26949585

  6. Evidence-based Medicine Search: a customizable federated search engine.

    PubMed

    Bracke, Paul J; Howse, David K; Keim, Samuel M

    2008-04-01

    This paper reports on the development of a tool by the Arizona Health Sciences Library (AHSL) for searching clinical evidence that can be customized for different user groups. The AHSL provides services to the University of Arizona's (UA's) health sciences programs and to the University Medical Center. Librarians at AHSL collaborated with UA College of Medicine faculty to create an innovative search engine, Evidence-based Medicine (EBM) Search, that provides users with a simple search interface to EBM resources and presents results organized according to an evidence pyramid. EBM Search was developed with a web-based configuration component that allows the tool to be customized for different specialties. Informal and anecdotal feedback from physicians indicates that EBM Search is a useful tool with potential in teaching evidence-based decision making. While formal evaluation is still being planned, a tool such as EBM Search, which can be configured for specific user populations, may help lower barriers to information resources in an academic health sciences center.

  7. Evidence-based Medicine Search: a customizable federated search engine

    PubMed Central

    Bracke, Paul J.; Howse, David K.; Keim, Samuel M.

    2008-01-01

    Purpose: This paper reports on the development of a tool by the Arizona Health Sciences Library (AHSL) for searching clinical evidence that can be customized for different user groups. Brief Description: The AHSL provides services to the University of Arizona's (UA's) health sciences programs and to the University Medical Center. Librarians at AHSL collaborated with UA College of Medicine faculty to create an innovative search engine, Evidence-based Medicine (EBM) Search, that provides users with a simple search interface to EBM resources and presents results organized according to an evidence pyramid. EBM Search was developed with a web-based configuration component that allows the tool to be customized for different specialties. Outcomes/Conclusion: Informal and anecdotal feedback from physicians indicates that EBM Search is a useful tool with potential in teaching evidence-based decision making. While formal evaluation is still being planned, a tool such as EBM Search, which can be configured for specific user populations, may help lower barriers to information resources in an academic health sciences center. PMID:18379665

  8. Experiments with hierarchical concept-based search.

    PubMed

    Moskovitch, Robert; Sa'adon, Roee; Behiri, Eytan; Martins, Susana; Weiss, Aviram; Shahar, Yuval

    2007-01-01

    Many digital libraries use hierarchical indexing schema, such as MeSH to enable concept based search in the retrieval phase. However, improving or outperforming the traditional full text search isn't trivial. We present an extensive set of experiments using a hierarchical concept based search retrieval method, applied in addition to several baselines, within the Vaidruya search and retrieval framework. Concept Based Search applied in addition to a low baseline is outperforming significantly, especially when queried on concepts in the third level and using disjunction within the hierarchical trees.

  9. In Search of Signature Pedagogy for PDS Teacher Education: A Review of Articles Published in "School-University Partnerships"

    ERIC Educational Resources Information Center

    Yendol-Hoppey, Diane; Franco, Yvonne

    2014-01-01

    ''In Search of Signature Pedagogy for PDS Teacher Education'' is a review of articles published in "School-University Partnerships" which emerged in response to Shulman's critique that we do not possess powerful, consistent models of practice that we can define and have deeply studied. To these ends, we searched…

  10. Privacy-Preserving Content-Based Publish/Subscribe Networks

    NASA Astrophysics Data System (ADS)

    Shikfa, Abdullatif; Önen, Melek; Molva, Refik

    Privacy and confidentiality are crucial issues in content-based publish/subscribe (CBPS) networks. We tackle the problem of end-user privacy in CBPS. This problem raises a challenging requirement for handling encrypted data for the purpose of routing based on protected content and encrypted subscription information. We suggest a solution based on a commutative multiple encryption scheme in order to allow brokers to operate in-network matching and content based routing without having access to the content of the packets. This is the first solution that avoids key sharing among end-users and targets an enhanced CBPS model where brokers can also be subscribers at the same time.

  11. Subscription merging in filter-based publish/subscribe systems

    NASA Astrophysics Data System (ADS)

    Zhang, Shengdong; Shen, Rui

    2013-03-01

    Filter-based publish/subscribe systems suffer from high subscription maintenance cost for each broker in the system stores a large number of subscriptions. Advertisement and covering are not sufficient to conquer such problem. Thus, subscription merging is proposed. However, current researches lack of an efficient and practical merging mechanism. In this paper, we propose a novel subscription merging mechanism. The mechanism is both time and space efficient, and can flexibly control the merging granularity. The merging mechanism has been verified through both theoretical and simulation-based evaluation.

  12. ArraySearch: A Web-Based Genomic Search Engine.

    PubMed

    Wilson, Tyler J; Ge, Steven X

    2012-01-01

    Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive.

  13. How to Search, Write, Prepare and Publish the Scientific Papers in the Biomedical Journals

    PubMed Central

    Masic, Izet

    2011-01-01

    This article describes the methodology of preparation, writing and publishing scientific papers in biomedical journals. given is a concise overview of the concept and structure of the System of biomedical scientific and technical information and the way of biomedical literature retreival from worldwide biomedical databases. Described are the scientific and professional medical journals that are currently published in Bosnia and Herzegovina. Also, given is the comparative review on the number and structure of papers published in indexed journals in Bosnia and Herzegovina, which are listed in the Medline database. Analyzed are three B&H journals indexed in MEDLINE database: Medical Archives (Medicinski Arhiv), Bosnian Journal of Basic Medical Sciences and Medical Gazette (Medicinki Glasnik) in 2010. The largest number of original papers was published in the Medical Archives. There is a statistically significant difference in the number of papers published by local authors in relation to international journals in favor of the Medical Archives. True, the Journal Bosnian Journal of Basic Medical Sciences does not categorize the articles and we could not make comparisons. Journal Medical Archives and Bosnian Journal of Basic Medical Sciences by percentage published the largest number of articles by authors from Sarajevo and Tuzla, the two oldest and largest university medical centers in Bosnia and Herzegovina. The author believes that it is necessary to make qualitative changes in the reception and reviewing of papers for publication in biomedical journals published in Bosnia and Herzegovina which should be the responsibility of the separate scientific authority/ committee composed of experts in the field of medicine at the state level. PMID:23572850

  14. Retrieving randomized controlled trials from medline: a comparison of 38 published search filters.

    PubMed

    McKibbon, Kathleen Ann; Wilczynski, Nancy Lou; Haynes, Robert Brian

    2009-09-01

    People search medline for trials of healthcare interventions for clinical decisions, or to produce systematic reviews, practice guidelines, or technology assessments. Finding all relevant randomized controlled trials (RCTs) with little extraneous material is challenging. To provide comparative data on the operating characteristics of search filters designed to retrieve RCTs from medline. We identified 38 filters. The testing database comprises handsearching data from 161 clinical journals indexed in medline. Sensitivity, specificity and precision were calculated. The number of terms and operating characteristics varied considerably. Comparing the retrieval against the single term 'randomized controlled trials.pt.' (sensitivity for retrieving RCTs, 93.7%), 24 of 38 filters had statistically higher sensitivity; 6 had a sensitivity of at least 99.0%. Four other filters had specificities (non retrieval of non-RCTs) that were statistically not different or better than the single term (97.6%). Precision was poor: only two filters had precision (proportion of retrieved articles that were RCTs) statistically similar to that of the single term (56.4%)-all others were lower. Filters with more search terms often had lower specificity, especially at high sensitivities. Many RCT filters exist (n = 38). These comparative data can direct the choice of an RCT filter.

  15. Knowledge-Based Search Tactics.

    ERIC Educational Resources Information Center

    Shute, Steven J.; Smith, Philip J.

    1993-01-01

    Describes an empirical study that was conducted to examine the performance of expert search intermediaries from Chemical Abstracts Service. Highlights include subject-independent and subject-dependent expertise; a model of the use of subject-specific knowledge; and implications for computerized intermediary systems and for training human…

  16. Knowledge-Based Search Tactics.

    ERIC Educational Resources Information Center

    Shute, Steven J.; Smith, Philip J.

    1993-01-01

    Describes an empirical study that was conducted to examine the performance of expert search intermediaries from Chemical Abstracts Service. Highlights include subject-independent and subject-dependent expertise; a model of the use of subject-specific knowledge; and implications for computerized intermediary systems and for training human…

  17. Publishing FAIR Data: An Exemplar Methodology Utilizing PHI-Base

    PubMed Central

    Rodríguez-Iglesias, Alejandro; Rodríguez-González, Alejandro; Irvine, Alistair G.; Sesma, Ane; Urban, Martin; Hammond-Kosack, Kim E.; Wilkinson, Mark D.

    2016-01-01

    Pathogen-Host interaction data is core to our understanding of disease processes and their molecular/genetic bases. Facile access to such core data is particularly important for the plant sciences, where individual genetic and phenotypic observations have the added complexity of being dispersed over a wide diversity of plant species vs. the relatively fewer host species of interest to biomedical researchers. Recently, an international initiative interested in scholarly data publishing proposed that all scientific data should be “FAIR”—Findable, Accessible, Interoperable, and Reusable. In this work, we describe the process of migrating a database of notable relevance to the plant sciences—the Pathogen-Host Interaction Database (PHI-base)—to a form that conforms to each of the FAIR Principles. We discuss the technical and architectural decisions, and the migration pathway, including observations of the difficulty and/or fidelity of each step. We examine how multiple FAIR principles can be addressed simultaneously through careful design decisions, including making data FAIR for both humans and machines with minimal duplication of effort. We note how FAIR data publishing involves more than data reformatting, requiring features beyond those exhibited by most life science Semantic Web or Linked Data resources. We explore the value-added by completing this FAIR data transformation, and then test the result through integrative questions that could not easily be asked over traditional Web-based data resources. Finally, we demonstrate the utility of providing explicit and reliable access to provenance information, which we argue enhances citation rates by encouraging and facilitating transparent scholarly reuse of these valuable data holdings. PMID:27433158

  18. Publishing FAIR Data: An Exemplar Methodology Utilizing PHI-Base.

    PubMed

    Rodríguez-Iglesias, Alejandro; Rodríguez-González, Alejandro; Irvine, Alistair G; Sesma, Ane; Urban, Martin; Hammond-Kosack, Kim E; Wilkinson, Mark D

    2016-01-01

    Pathogen-Host interaction data is core to our understanding of disease processes and their molecular/genetic bases. Facile access to such core data is particularly important for the plant sciences, where individual genetic and phenotypic observations have the added complexity of being dispersed over a wide diversity of plant species vs. the relatively fewer host species of interest to biomedical researchers. Recently, an international initiative interested in scholarly data publishing proposed that all scientific data should be "FAIR"-Findable, Accessible, Interoperable, and Reusable. In this work, we describe the process of migrating a database of notable relevance to the plant sciences-the Pathogen-Host Interaction Database (PHI-base)-to a form that conforms to each of the FAIR Principles. We discuss the technical and architectural decisions, and the migration pathway, including observations of the difficulty and/or fidelity of each step. We examine how multiple FAIR principles can be addressed simultaneously through careful design decisions, including making data FAIR for both humans and machines with minimal duplication of effort. We note how FAIR data publishing involves more than data reformatting, requiring features beyond those exhibited by most life science Semantic Web or Linked Data resources. We explore the value-added by completing this FAIR data transformation, and then test the result through integrative questions that could not easily be asked over traditional Web-based data resources. Finally, we demonstrate the utility of providing explicit and reliable access to provenance information, which we argue enhances citation rates by encouraging and facilitating transparent scholarly reuse of these valuable data holdings.

  19. Xerox trails: a new web-based publishing technology

    NASA Astrophysics Data System (ADS)

    Rao, Venkatesh G.; Vandervort, David; Silverstein, Jesse

    2010-02-01

    Xerox Trails is a new digital publishing model developed at the Xerox Research Center, Webster. The primary purpose of the technology is to allow Web users and publishers to collect, organize and present information in the form of a useful annotated narrative (possibly non-sequential) with editorial content and metadata, that can be consumed both online and offline. The core concept is a trail: a digital object that improves online content production, consumption and navigation user experiences. When appropriate, trails can also be easily sequenced and transformed into printable documents, thereby bridging the gap between online and offline content experiences. The model is partly inspired by Vannevar Bush's influential idea of the "Memex" [1] which has inspired several generations of Web technology [2]. Xerox Trails is a realization of selected elements from the idea of the Memex, along with several original design ideas. It is based on a primitive data construct, the trail. In Xerox Trails, the idea of a trail is used to support the architecture of a Web 2.0 product suite called Trailmeme, that includes a destination Web site, plugins for major content management systems, and a browser toolbar.

  20. Methodological quality assessment of paper-based systematic reviews published in oral health.

    PubMed

    Wasiak, J; Shen, A Y; Tan, H B; Mahar, R; Kan, G; Khoo, W R; Faggion, C M

    2016-04-01

    This study aimed to conduct a methodological assessment of paper-based systematic reviews (SR) published in oral health using a validated checklist. A secondary objective was to explore temporal trends on methodological quality. Two electronic databases (OVID Medline and OVID EMBASE) were searched for paper-based SR of interventions published in oral health from inception to October 2014. Manual searches of the reference lists of paper-based SR were also conducted. Methodological quality of included paper-based SR was assessed using an 11-item questionnaire, Assessment of Multiple Systematic Reviews (AMSTAR) checklist. Methodological quality was summarized using the median and inter-quartile range (IQR) of the AMSTAR score over different categories and time periods. A total of 643 paper-based SR were included. The overall median AMSTAR score was 4 (IQR 2-6). The highest median score (5) was found in the pain dentistry and periodontology fields, while the lowest median score (3) was found in implant dentistry, restorative dentistry, oral medicine, and prosthodontics. The number of paper-based SR per year and the median AMSTAR score increased over time (median score in 1990s was 2 (IQR 2-3), 2000s was 4 (IQR 2-5), and 2010 onwards was 5 (IQR 3-6)). Although the methodological quality of paper-based SR published in oral health has improved in the last few years, there is still scope for improving quality in most evaluated dental specialties. Large-scale assessment of methodological quality of dental SR highlights areas of methodological strengths and weaknesses that can be targeted in future publications to encourage better quality review methodology.

  1. Retinoblastoma: Recent trends A mini review based on published literature

    PubMed Central

    Khetan, Vikas; Gupta, Aditi; Gopal, Lingam

    2011-01-01

    Retinoblastoma (RB) is the most common intraocular malignancy in children. Recently, there have been significant advances made in the molecular pathology and the management of the disease. Last decade has witnessed better understanding of the genetics of RB, the discovery of new tumor markers expressed by the RB tumors, the identification of high-risk histopathological factors following enucleation, and newer methods of treatment including periocular chemotherapy and superselective intraarterial chemotherapy. All these advances have translated in improved survival rates for the affected children, improved rates of eye salvage, and improved visual outcomes. This article briefly reviews these advances. Method of Literature Search: Literature on the Medline database was searched using the PubMed interface. The search strategy included MeSH and natural language terms using the keywords mentioned. Reference lists in retrieved articles and textbooks were also searched for relevant references. PMID:22279397

  2. Reproducibility of Search Strategies Is Poor in Systematic Reviews Published in High-Impact Pediatrics, Cardiology and Surgery Journals: A Cross-Sectional Study

    PubMed Central

    2016-01-01

    Background A high-quality search strategy is considered an essential component of systematic reviews but many do not contain reproducible search strategies. It is unclear if low reproducibility spans medical disciplines, is affected by librarian/search specialist involvement or has improved with increased awareness of reporting guidelines. Objectives To examine the reporting of search strategies in systematic reviews published in Pediatrics, Surgery or Cardiology journals in 2012 and determine rates and predictors of including a reproducible search strategy. Methods We identified all systematic reviews published in 2012 in the ten highest impact factor journals in Pediatrics, Surgery and Cardiology. Each search strategy was coded to indicate what elements were reported and whether the overall search was reproducible. Reporting and reproducibility rates were compared across disciplines and we measured the influence of librarian/search specialist involvement, discipline or endorsement of a reporting guideline on search reproducibility. Results 272 articles from 25 journals were included. Reporting of search elements ranged widely from 91% of articles naming search terms to 33% providing a full search strategy and 22% indicating the date the search was executed. Only 22% of articles provided at least one reproducible search strategy and 13% provided a reproducible strategy for all databases searched in the article. Librarians or search specialists were reported as involved in 17% of articles. There were strong disciplinary differences on the reporting of search elements. In the multivariable analysis, only discipline (Pediatrics) was a significant predictor of the inclusion of a reproducible search strategy. Conclusions Despite recommendations to report full, reproducible search strategies, many articles still do not. In addition, authors often report a single strategy as covering all databases searched, further decreasing reproducibility. Further research is needed

  3. Model-based Tomographic Reconstruction Literature Search

    SciTech Connect

    Chambers, D H; Lehman, S K

    2005-11-30

    In the process of preparing a proposal for internal research funding, a literature search was conducted on the subject of model-based tomographic reconstruction (MBTR). The purpose of the search was to ensure that the proposed research would not replicate any previous work. We found that the overwhelming majority of work on MBTR which used parameterized models of the object was theoretical in nature. Only three researchers had applied the technique to actual data. In this note, we summarize the findings of the literature search.

  4. Ozone in the stratosphere. (Latest citations from the NTIS Bibliographic database). Published Search

    SciTech Connect

    Not Available

    1993-09-01

    The bibliography contains citations concerning empirical and theoretical studies and analyses of stratospheric ozone. The processing of upper atmospheric ozone concentrations that vary with ozone transport, formation, and depletion, and data collection using ground-based, airborne and satellite-borne instrumentation and sensors are examined. Citations cover studies on atmospheric composition, reaction kinetics, particle physics, chemical reactions, photochemistry, and atmospheric models of ozone. Investigations are based on the photochemistry, ozone constituents, and long-term measurement data. References to the Antarctic October depletion phenomenon are included. (Contains 250 citations and includes a subject term index and title list.)

  5. Ozone in the stratosphere. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    Not Available

    1994-03-01

    The bibliography contains citations concerning empirical and theoretical studies and analyses of stratospheric ozone. The processing of upper atmospheric ozone concentrations that vary with ozone transport, formation, and depletion, and data collection using ground-based, airborne and satellite-borne instrumentation and sensors are examined. Citations cover studies on atmospheric composition, reaction kinetics, particle physics, chemical reactions, photochemistry, and atmospheric models of ozone. Investigations are based on the photochemistry, ozone constituents, and long-term measurement data. References to the Antarctic October depletion phenomenon are included. (Contains 250 citations and includes a subject term index and title list.)

  6. Recycled materials in asphalt pavements. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1995-03-01

    The bibliography contains citations concerning the recycling of asphalt pavement materials for road construction. Citations discuss asphalt concrete mixtures and recycling, recycled materials testing and evaluation, and pavement bases. Engineering and environmental aspects of recycled materials are examined. (Contains a minimum of 78 citations and includes a subject term index and title list.)

  7. Water pollution analysis and detection. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1995-08-01

    The bibliography contains citations concerning water pollution analysis, detection, monitoring, and regulation. Citations review online systems, bioassay monitoring, laser-based detection, sensor and biosensor systems, metabolic analyzers, and microsystem techniques. References cover fiber-optic portable detection instruments and rapid detection of toxicants in drinking water. (Contains 50-250 citations and includes a subject term index and title list.)

  8. A scoping review of 10 years of published literature on community-based rehabilitation.

    PubMed

    Cleaver, Shaun; Nixon, Stephanie

    2014-01-01

    To identify the characteristics of peer-reviewed literature on community-based rehabilitation (CBR) in low- and middle-income countries published in English from 2003 to 2012. This scoping review involved a systematic search of electronic databases using specific keyword/subject heading combinations. Journal articles were included if they were published in English, used "CBR" as related to rehabilitation with persons with disabilities and not limited to high-income countries (HICs). Data were charted according to both pre-determined and emergent categories. A subset of articles was charted by two reviewers to ensure reliability of variables. A total of 114 articles were included. Fifty-two articles presented empirical research and 49 were published in one of two journals. The articles represented CBR activity in 26 specific countries, although only two of these were in Europe and only one was in the Americas. Authors were predominantly affiliated at universities and in HICs. This scoping review identified and characterized a large pool of literature on CBR, facilitating its incorporation into research and practice. Future research should examine the engagement of persons with disabilities in creating CBR literature, and analysis of literature in languages other than English. Implications for Rehabilitation Community-based rehabilitation (CBR) has been promoted as a rehabilitation strategy of choice in low- and middle-income countries (LMICs), but it has been critiqued for lack of an evidence base. A large number (114) of peer-reviewed articles were published on CBR between 2003 and 2012. Just under half of these articles (45%) presented empirical research, indicating that the evidence base for CBR is growing but will benefit from continued, rigorous inquiry. Furthermore, researchers from LMICs appear to be largely under-represented in published CBR research, flagging the need to support LMIC partners to share their CBR research in peer-reviewed journals.

  9. Materials for electrical battery technology. (Latest citations from Metadex). Published Search

    SciTech Connect

    1995-12-01

    The bibliography contains citations concerning materials used in batteries. Among materials discussed are lead, nickel, magnesium and zinc alloys, rare-earth-based hydrogen, aluminum, and lead-calcium alloys. Recovery and recycling of polypropylene from automotive batteries are referenced, and use of polyphase as rechargeable electrodes in advanced battery systems is also examined.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  10. Remote sensing of ocean pollution. (Latest citations from the Aerospace database). Published Search

    SciTech Connect

    1995-02-01

    The bibliography contains citations concerning the use of remote sensing for the control and monitoring of ocean pollution. Citations discuss remote sensing techniques and instrumentations, including airborne and satellite-borne photography, microwave radiometry, laser fluorescence, and radar imagery. Topics include oil spills, marine ecosystems, land-based pollutants, ocean dumping, remote sensing capability and reliability, and pollution transport. (Contains a minimum of 109 citations and includes a subject term index and title list.)

  11. Water pollution analysis and detection. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1996-08-01

    The bibliography contains citations concerning water pollution analysis, detection, monitoring, and regulation. Citations review online systems, bioassay monitoring, laser-based detection, sensor and biosensor systems, metabolic analyzers, and microsystem techniques. References cover fiber-optic portable detection instruments and rapid detection of toxicants in drinking water. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  12. Corrosion resistant coatings. (Latest citations from the EI compendex*plus database). Published Search

    SciTech Connect

    1995-01-01

    The bibliography contains citations concerning the anticorrosive behavior of protective coatings based on such materials as ceramics, metals, and polymers. Topics include high and low temperature corrosion, surface structure, mechanical and chemical properties, applications, and performance evaluations. Paints and powder coatings, and methods of application are also considered. Protective coatings for specific applications such as gas turbines, coal gasification, power plants, papermaking, carbon steels, reinforced concrete, pipelines, antifouling coatings, and conversion coatings are examined in separate bibliographies. (Contains 250 citations and includes a subject term index and title list.)

  13. Web-based magazine design for self publishers

    NASA Astrophysics Data System (ADS)

    Hunter, Andrew; Slatter, David; Greig, Darryl

    2011-03-01

    Short run printing technology and web services such as MagCloud provide new opportunities for long-tail magazine publishing. They enable self publishers to supply magazines to a wide range of communities, including groups that are too small to be viable as target communities for conventional publishers. In a Web 2.0 world where users constantly discover new services and where they may be infrequent patrons of any single service, it is unreasonable to expect users to learn the complex service behaviors. Furthermore, we want to open up publishing opportunities to novices who are unlikely to have prior experience of publishing and who lack design expertise. Magazine design automation is an ambitious goal, but recent progress with another web service, Autophotobook, proves that some level of automation of publication design is feasible. This paper describes our current research effort to extend the automation capabilities of Autophotobook to address the issues of magazine design so that we can provide a service to support professional-quality self publishing by novice users for a wide range of community types and sizes.

  14. Chemical and biological warfare: Protection, decontamination, and disposal. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1997-11-01

    The bibliography contains citations concerning the means to defend against chemical and biological agents used in military operations, and to eliminate the effects of such agents on personnel, equipment, and grounds. Protection is accomplished through protective clothing and masks, and in buildings and shelters through filtration. Elimination of effects includes decontamination and removal of the agents from clothing, equipment, buildings, grounds, and water, using chemical deactivation, incineration, and controlled disposal of material in injection wells and ocean dumping. Other Published Searches in this series cover chemical warfare detection; defoliants; general studies; biochemistry and therapy; and biology, chemistry, and toxicology associated with chemical warfare agents.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  15. Robots for hazardous duties: Military, space, and nuclear facility applications. (Latest citations from the NTIS bibliographic database). Published Search

    SciTech Connect

    1993-09-01

    The bibliography contains citations concerning the design and application of robots used in place of humans where the environment could be hazardous. Military applications include autonomous land vehicles, robotic howitzers, and battlefield support operations. Space operations include docking, maintenance, mission support, and intra-vehicular and extra-vehicular activities. Nuclear applications include operations within the containment vessel, radioactive waste operations, fueling operations, and plant security. Many of the articles reference control techniques and the use of expert systems in robotic operations. Applications involving industrial manufacturing, walking robots, and robot welding are cited in other published searches in this series. (Contains a minimum of 183 citations and includes a subject term index and title list.)

  16. [Evidence-based practices published in Brazil: identification and analysis of their types and methodological approches].

    PubMed

    Lacerda, Rúbia Aparecida; Nunes, Bruna Kosar; Batista, Arlete de Oliveira; Egry, Emiko Yoshikawa; Graziano, Kazuko Uchikawa; Angelo, Margareth; Merighi, Miriam Aparecida Barbosa; Lopes, Nadir Aparecida; Fonseca, Rosa Maria Godoy Serpa da; Castilho, Valéria

    2011-06-01

    This is an integrative review of Brazilian studies on evidence-based practices (EBP) in health, published in ISI/JCR journals in the last 10 years. The aim was to identify the specialty areas that most accomplished these studies, their foci and methodological approaches. Based on inclusion criteria, 144 studies were selected. The results indicate that most EBP studies addressed childhood and adolescence, infectious diseases, psychiatrics/mental health and surgery. The predominant foci were prevention, treatment/rehabilitation, diagnosis and assessment. The most used methods were systematic review with or without meta-analysis, protocol review or synthesis of available evidence studies, and integrative review. A strong multiprofessional expansion of EBP is found in Brazil, contributing to the search for more selective practices by collecting, recognizing and critically analyzing the produced knowledge. The study also contributes to the analysis itself of ways to do research and new research possibilities.

  17. Ontology-Based Search of Genomic Metadata.

    PubMed

    Fernandez, Javier D; Lenzerini, Maurizio; Masseroli, Marco; Venco, Francesco; Ceri, Stefano

    2016-01-01

    The Encyclopedia of DNA Elements (ENCODE) is a huge and still expanding public repository of more than 4,000 experiments and 25,000 data files, assembled by a large international consortium since 2007; unknown biological knowledge can be extracted from these huge and largely unexplored data, leading to data-driven genomic, transcriptomic, and epigenomic discoveries. Yet, search of relevant datasets for knowledge discovery is limitedly supported: metadata describing ENCODE datasets are quite simple and incomplete, and not described by a coherent underlying ontology. Here, we show how to overcome this limitation, by adopting an ENCODE metadata searching approach which uses high-quality ontological knowledge and state-of-the-art indexing technologies. Specifically, we developed S.O.S. GeM (http://www.bioinformatics.deib.polimi.it/SOSGeM/), a system supporting effective semantic search and retrieval of ENCODE datasets. First, we constructed a Semantic Knowledge Base by starting with concepts extracted from ENCODE metadata, matched to and expanded on biomedical ontologies integrated in the well-established Unified Medical Language System. We prove that this inference method is sound and complete. Then, we leveraged the Semantic Knowledge Base to semantically search ENCODE data from arbitrary biologists' queries. This allows correctly finding more datasets than those extracted by a purely syntactic search, as supported by the other available systems. We empirically show the relevance of found datasets to the biologists' queries.

  18. Quality of reporting of systematic reviews published in "evidence-based" Chinese journals.

    PubMed

    Li, Jin-Long; Ge, Long; Ma, Ji-Chun; Zeng, Qiao-Ling; Yao, Lu; An, Ni; Ding, Jie-Xian; Gan, Yu-Hong; Tian, Jin-Hui

    2014-06-07

    The number of systematic reviews (SRs)/meta-analyses (MAs) has increased dramatically in China over the past decades. However, evaluation of quality of reporting of systematic reviews published has not been undertaken. The objective of this study is to evaluate the quality of reporting of SRs/MAs assessing efficacy and/or harms of clinical interventions published in "evidence-based" Chinese journals. Web-based database searches were conducted for the Chinese Journal of Evidence-based Medicine, the Journal of Evidence-Based Medicine, the Chinese Journal of Evidence Based Pediatrics, and the Chinese Journal of Evidence-Based Cardiovascular Medicine. SRs/MAs assessing efficacy and/or harms of clinical interventions were included. The cut-off was December 31st 2011. The PRISMA statement was applied to assess the quality of reporting. Each item was assessed as follows: 'Yes' for total compliance, scored '1'; 'partial' for partial compliance, scored '0.5'; and 'No' for non-compliance, scored '0'. The review was considered to have major flaws if it received a total score of ≤15.0, minor flaws if it received a total score of 15.5 to 21.0, and minimal flaws if it received a total score 21.5 to 27.0. Odds ratios were used for binary variables, and the mean difference was used for continuous variables. Analyses were performed using RevMan 5.0 software. Overall, 487 SRs/MAs were identified and assessed. The included reviews had medium quality with minor flaws based on PRISMA total scores (range: 8.5-26.0; mean: 19.6 ± 3.3). The stratified analysis showed that SRs/MAs with more than 3 authors, from a university, hospital + university cooperation, multiple affiliations (≥2), and funding have significantly higher quality of reporting of SRs/MAs; 58% of the included reviews were considered to have minor flaws (total score of 15.6 to 21.0). Only 9.6% of reviews were considered to have major flaws. Specific areas needing improvement in reporting include the abstract

  19. ARA testbed template based UHE neutrino search

    NASA Astrophysics Data System (ADS)

    Prohira, Steven

    2014-03-01

    The Askaryan Radio Array (ARA) is an in-ice Antarctic neutrino detector deployed near the South Pole. ARA is designed to detect ultra high energy (UHE) neutrinos in the range of 0.1-10 EeV. Data from the ARA testbed, deployed in the 2010-2011 season, is used for a template based neutrino search. Askaryan Radio Array.

  20. Chemical Information in Scirus and BASE (Bielefeld Academic Search Engine)

    ERIC Educational Resources Information Center

    Bendig, Regina B.

    2009-01-01

    The author sought to determine to what extent the two search engines, Scirus and BASE (Bielefeld Academic Search Engines), would be useful to first-year university students as the first point of searching for chemical information. Five topics were searched and the first ten records of each search result were evaluated with regard to the type of…

  1. Chemical Information in Scirus and BASE (Bielefeld Academic Search Engine)

    ERIC Educational Resources Information Center

    Bendig, Regina B.

    2009-01-01

    The author sought to determine to what extent the two search engines, Scirus and BASE (Bielefeld Academic Search Engines), would be useful to first-year university students as the first point of searching for chemical information. Five topics were searched and the first ten records of each search result were evaluated with regard to the type of…

  2. Disease Related Knowledge Summarization Based on Deep Graph Search.

    PubMed

    Wu, Xiaofang; Yang, Zhihao; Li, ZhiHeng; Lin, Hongfei; Wang, Jian

    2015-01-01

    The volume of published biomedical literature on disease related knowledge is expanding rapidly. Traditional information retrieval (IR) techniques, when applied to large databases such as PubMed, often return large, unmanageable lists of citations that do not fulfill the searcher's information needs. In this paper, we present an approach to automatically construct disease related knowledge summarization from biomedical literature. In this approach, firstly Kullback-Leibler Divergence combined with mutual information metric is used to extract disease salient information. Then deep search based on depth first search (DFS) is applied to find hidden (indirect) relations between biomedical entities. Finally random walk algorithm is exploited to filter out the weak relations. The experimental results show that our approach achieves a precision of 60% and a recall of 61% on salient information extraction for Carcinoma of bladder and outperforms the method of Combo.

  3. Disease Related Knowledge Summarization Based on Deep Graph Search

    PubMed Central

    Wu, Xiaofang; Yang, Zhihao; Li, ZhiHeng; Lin, Hongfei; Wang, Jian

    2015-01-01

    The volume of published biomedical literature on disease related knowledge is expanding rapidly. Traditional information retrieval (IR) techniques, when applied to large databases such as PubMed, often return large, unmanageable lists of citations that do not fulfill the searcher's information needs. In this paper, we present an approach to automatically construct disease related knowledge summarization from biomedical literature. In this approach, firstly Kullback-Leibler Divergence combined with mutual information metric is used to extract disease salient information. Then deep search based on depth first search (DFS) is applied to find hidden (indirect) relations between biomedical entities. Finally random walk algorithm is exploited to filter out the weak relations. The experimental results show that our approach achieves a precision of 60% and a recall of 61% on salient information extraction for Carcinoma of bladder and outperforms the method of Combo. PMID:26413521

  4. The schizophrenia stigma and mass media: a search for news published by wide circulation media in Brazil.

    PubMed

    Bevilacqua Guarniero, Francisco; Bellinghini, Ruth Helena; Gattaz, Wagner Farid

    2017-06-01

    Schizophrenia is the most common illness used today as a metaphor in the media and routinely appears associated with crime and violence with no medical or scientific rigor, reinforcing the stigma against this disorder. Evaluation of the presence of structural stigma in the Brazilian media by means of a survey of printed news and the Internet using the term schizophrenia and its correlates under three aspects: (a) medical and scientific uses, (b) assigning a diagnosis of schizophrenia to crime suspects with little or no medical or scientific rigor, and (c) the metaphorical use. The study was conducted in three stages: search for publications, classification of items found and analysis of the context in which they were published. The survey was conducted in two periods: 2008 and 2011, the first being restricted to the newspaper Folha de S. Paulo and the second extended to the homepage of the main Brazilian print media. We found 229 texts, distributed as follows: 89 (39%) records as science and health, with a tendency to impersonality; 62 (27%) records as crime and violence, in which the 'diagnosis' of schizophrenia is given by lay people and 'supported' by an archeology of the life of the suspect which enlists all sorts of non-standard behavior; and 78 (34%) records of metaphorical use, always with a negative meaning. Most of the texts found (a) does not give voice to people with schizophrenia and their suffering, (b) trivializes the use of this psychiatric illness out of context to describe contradictory or of dubious character political and economic decisions, and (c) reinforces the stigma that lays over the bearer of schizophrenia individualizing them only in rare violent cases with a supposed diagnosis.

  5. The Pricing of Information--A Search-Based Approach to Pricing an Online Search Service.

    ERIC Educational Resources Information Center

    Boyle, Harry F.

    1982-01-01

    Describes innovative pricing structure consisting of low connect time fee, print fees, and search fees, offered by Chemical Abstracts Service (CAS) ONLINE--an online searching system used to locate chemical substances. Pricing options considered by CAS, the search-based pricing approach, and users' reactions to pricing structures are noted. (EJS)

  6. The Pricing of Information--A Search-Based Approach to Pricing an Online Search Service.

    ERIC Educational Resources Information Center

    Boyle, Harry F.

    1982-01-01

    Describes innovative pricing structure consisting of low connect time fee, print fees, and search fees, offered by Chemical Abstracts Service (CAS) ONLINE--an online searching system used to locate chemical substances. Pricing options considered by CAS, the search-based pricing approach, and users' reactions to pricing structures are noted. (EJS)

  7. A Critical Review of Search Strategies Used in Recent Systematic Reviews Published in Selected Prosthodontic and Implant-Related Journals: Are Systematic Reviews Actually Systematic?

    PubMed

    Layton, Danielle

    The aim of this study was to outline how search strategies can be systematic, to examine how the searches in recent systematic reviews in prosthodontic and implant-related journals were structured, and to determine whether the search strategies used in those articles were systematic. A total of 103 articles published as systematic reviews and indexed in Medline between January 2013 and May 2016 were identified from eight prosthodontic and implant journals and reviewed. The search strategies were considered systematic when they met the following criteria: (1) more than one electronic database was searched, (2) more than one searcher was clearly involved, (3) both text words and indexing terms were clearly included in the search strategy, (4) a hand search of selected journals or reference lists was undertaken, (5) gray research was specifically sought, and (6) the articles were published in English and at least one other language. The data were tallied and qualitatively assessed. The majority of articles reported on implants (54%), followed by tooth-supported fixed prosthodontics (13%). A total of 23 different electronic resources were consulted, including Medline (by 100% of articles), the Cochrane Library (52%), and Embase (37%). The majority consulted more than one electronic resource (71%), clearly included more than one searcher (73%), and employed a hand search of either selected journals or reference lists (86%). Less than half used both text words and indexing terms to identify articles (42%), while 15% actively sought gray research. Articles published in languages other than English were considered in 63 reviews, but only 14 had no language restrictions. Of the 103 articles, 5 completed search strategies that met all 6 criteria, and a further 12 met 5 criteria. Two articles did not fulfill any of the criteria. More than 95% of recent prosthodontic and implant review articles published in the selected journals failed to use search strategies that were

  8. [Searching for evidence-based data].

    PubMed

    Dufour, J-C; Mancini, J; Fieschi, M

    2009-08-01

    The foundation of evidence-based medicine is critical analysis and synthesis of the best data available concerning a given health problem. These factual data are accessible because of the availability on the Internet of web tools specialized in research for scientific publications. A bibliographic database is a collection of bibliographic references describing the documents indexed. Such a reference includes at least the title, summary (or abstract), a set of keywords, and the type of publication. To conduct a strategically effective search, it is necessary to formulate the question - clinical, diagnostic, prognostic, or related to treatment or prevention - in a form understandable by the research engine. Moreover, it is necessary to choose the specific database or databases, which may have particular specificity, and to analyze the results rapidly to refine the strategy. The search for information is facilitated by the knowledge of the standardized terms commonly used to describe the desired information. These come from a specific thesaurus devoted to document indexing. The most frequently used is MeSH (Medical Subject Heading). The principal bibliographic database whose references include a set of describers from the MeSH thesaurus is Medical Literature Analysis and Retrieval System Online (Medline), which has in turn become a subpart of a still more vast bibliography called PubMed, which indexes an additional 1.4 million references. Numerous other databases are maintained by national or international entities. These include the Cochrane Library, Embase, and the PASCAL and FRANCIS databases.

  9. Methodological trends in studies based on verbal autopsies before and after published guidelines

    PubMed Central

    Kengne, Andre Pascal; Neal, Bruce

    2009-01-01

    Abstract Objective To report on the uptake of guidelines published in the early 1990s with specific recommendations about the design of future studies based on verbal autopsy conducted for mortality surveillance. Methods We conducted a systematic literature search of all verbal autopsy studies published before January 2006 and extracted from the studies a standard set of data. We then compared studies designed before and after the recommendations were issued in terms of seven key methodological indicators. Findings We found 102 studies conducted in 39 countries; 60 were designed before and 42 after the guidelines were issued. The methods used in these 102 studies varied considerably. While some encouraging trends were noted, there is no evidence that the design recommendations have been systematically implemented. Specifically, there was no clear increase in the proportion of studies with a combined questionnaire (63% before recommendations versus 74% after; P = 0.3), a trained interviewer (70% versus 70%; P = 1.0), a suitable respondent (98% versus 100%; P = 1.0), an optimal recall period (84% versus 97%; P = 0.2), predefined algorithms (28% versus 38%; P = 0.4), an option for assigning multiple causes of death (30% versus 38%; P = 0.3), or a follow-up validation study (83% versus 72%; P = 0.7). Conclusion Expert recommendations for optimal design of verbal autopsy studies have been incompletely implemented to date. Better uptake of design recommendations through enhanced collaboration between research teams is likely to produce better mortality statistics from an increasing number of verbal autopsy studies. PMID:19784447

  10. Published and perished? The influence of the searched protein database on the long-term storage of proteomics data.

    PubMed

    Griss, Johannes; Côté, Richard G; Gerner, Christopher; Hermjakob, Henning; Vizcaíno, Juan Antonio

    2011-09-01

    In proteomics, protein identifications are reported and stored using an unstable reference system: protein identifiers. These proprietary identifiers are created individually by every protein database and can change or may even be deleted over time. To estimate the effect of the searched protein sequence database on the long-term storage of proteomics data we analyzed the changes of reported protein identifiers from all public experiments in the Proteomics Identifications (PRIDE) database by November 2010. To map the submitted protein identifier to a currently active entry, two distinct approaches were used. The first approach used the Protein Identifier Cross Referencing (PICR) service at the EBI, which maps protein identifiers based on 100% sequence identity. The second one (called logical mapping algorithm) accessed the source databases and retrieved the current status of the reported identifier. Our analysis showed the differences between the main protein databases (International Protein Index (IPI), UniProt Knowledgebase (UniProtKB), National Center for Biotechnological Information nr database (NCBI nr), and Ensembl) in respect to identifier stability. For example, whereas 20% of submitted IPI entries were deleted after two years, virtually all UniProtKB entries remained either active or replaced. Furthermore, the two mapping algorithms produced markedly different results. For example, the PICR service reported 10% more IPI entries deleted compared with the logical mapping algorithm. We found several cases where experiments contained more than 10% deleted identifiers already at the time of publication. We also assessed the proportion of peptide identifications in these data sets that still fitted the originally identified protein sequences. Finally, we performed the same overall analysis on all records from IPI, Ensembl, and UniProtKB: two releases per year were used, from 2005. This analysis showed for the first time the true effect of changing protein

  11. Pre filtered Dynamic Time Warping for Posteriorgram Based Keyword Search

    DTIC Science & Technology

    2017-02-09

    PRE-FILTERED DYNAMIC TIME WARPING FOR POSTERIORGRAM BASED KEYWORD SEARCH Gozde Cetinkaya, Batuhan Gundogdu, Murat Saraclar Bogazici University...In this study, we present a pre-filtering method for dynamic time warping (DTW) to improve the efficiency of a posterior- gram based keyword search...queries and the in-vocabulary (IV) queries. Index Terms— keyword search, posteriorgram, dynamic time warping 1. INTRODUCTION The aim of keyword search

  12. HTTP-based Search and Ordering Using ECHO's REST-based and OpenSearch APIs

    NASA Astrophysics Data System (ADS)

    Baynes, K.; Newman, D. J.; Pilone, D.

    2012-12-01

    Metadata is an important entity in the process of cataloging, discovering, and describing Earth science data. NASA's Earth Observing System (EOS) ClearingHOuse (ECHO) acts as the core metadata repository for EOSDIS data centers, providing a centralized mechanism for metadata and data discovery and retrieval. By supporting both the ESIP's Federated Search API and its own search and ordering interfaces, ECHO provides multiple capabilities that facilitate ease of discovery and access to its ever-increasing holdings. Users are able to search and export metadata in a variety of formats including ISO 19115, json, and ECHO10. This presentation aims to inform technically savvy clients interested in automating search and ordering of ECHO's metadata catalog. The audience will be introduced to practical and applicable examples of end-to-end workflows that demonstrate finding, sub-setting and ordering data that is bound by keyword, temporal and spatial constraints. Interaction with the ESIP OpenSearch Interface will be highlighted, as will ECHO's own REST-based API.

  13. A lunar base for SETI (Search for Extraterrestrial Intelligence)

    NASA Technical Reports Server (NTRS)

    Oliver, Bernard M.

    1988-01-01

    The possibilities of using lanar based radio antennas in search of intelligent extraterrestrial communications is explored. The proposed NASA search will have two search modes: (1) An all sky survey covering the frequency range from 1 to 10 GHz; and (2) A high sensitivity targeted search listening for signals from the approx. 800 solar type stars within 80 light years of the Sun, and covering 1 to 3 GHz.

  14. Research of Search Template Based on Distributed Computing

    NASA Astrophysics Data System (ADS)

    Xiao, Yao; Huang, Long-Jun; Zuo, Yi

    Aiming at the problem of requirement identification in the field of search engine, we proposed a scheme that makes use of nature language template. In the help of map-reduce analyze of the user searching log, high frequency template can be obtained. Besides, based on tire tree we designed a algorithm that can make the search engine distinguish user requirements using the template. In that case, the search engine can offer different service according to the user requirements.

  15. Did online publishers "get it right"? Using a naturalistic search strategy to review cognitive health promotion content on internet webpages.

    PubMed

    Hunter, P V; Delbaere, M; O'Connell, M E; Cammer, A; Seaton, J X; Friedrich, T; Fick, F

    2017-06-15

    One of the most common uses of the Internet is to search for health-related information. Although scientific evidence pertaining to cognitive health promotion has expanded rapidly in recent years, it is unclear how much of this information has been made available to Internet users. Thus, the purpose of our study was to assess the reliability and quality of information about cognitive health promotion encountered by typical Internet users. To generate a list of relevant search terms employed by Internet users, we entered seed search terms in Google Trends and recorded any terms consistently used in the prior 2 years. To further approximate the behaviour of typical Internet users, we entered each term in Google and sampled the first two relevant results. This search, completed in October 2014, resulted in a sample of 86 webpages, 48 of which had content related to cognitive health promotion. An interdisciplinary team rated the information reliability and quality of these webpages using a standardized measure. We found that information reliability and quality were moderate, on average. Just one retrieved page mentioned best practice, national recommendations, or consensus guidelines by name. Commercial content (i.e., product promotion, advertising content, or non-commercial) was associated with differences in reliability and quality, with product promoter webpages having the lowest mean reliability and quality ratings. As efforts to communicate the association between lifestyle and cognitive health continue to expand, we offer these results as a baseline assessment of the reliability and quality of cognitive health promotion on the Internet.

  16. Searching the ERIC Data Base at UNM.

    ERIC Educational Resources Information Center

    Neville, Sandra H.

    The University of New Mexico (UNM) General Library supports the locally-managed ERIC search service. During the 1973/1974 fiscal year, more than 3,000 searches were processed by the UNM Division of Computer and Information Science using a specially developed retrieval program, GANDALF (General Alpha-Numeric Direct Access Library Facility). This…

  17. Restricted random search method based on taboo search in the multiple minima problem

    NASA Astrophysics Data System (ADS)

    Hong, Seung Do; Jhon, Mu Shik

    1997-03-01

    The restricted random search method is proposed as a simple Monte Carlo sampling method to search minima fast in the multiple minima problem. This method is based on taboo search applied recently to continuous test functions. The concept of the taboo region instead of the taboo list is used and therefore the sampling of a region near an old configuration is restricted in this method. This method is applied to 2-dimensional test functions and the argon clusters. This method is found to be a practical and efficient method to search near-global configurations of test functions and the argon clusters.

  18. Online-Based Approaches to Identify Real Journals and Publishers from Hijacked Ones.

    PubMed

    Asadi, Amin; Rahbar, Nader; Asadi, Meisam; Asadi, Fahime; Khalili Paji, Kokab

    2017-02-01

    The aim of the present paper was to introduce some online-based approaches to evaluate scientific journals and publishers and to differentiate them from the hijacked ones, regardless of their disciplines. With the advent of open-access journals, many hijacked journals and publishers have deceitfully assumed the mantle of authenticity in order to take advantage of researchers and students. Although these hijacked journals and publishers can be identified through checking their advertisement techniques and their websites, these ways do not always result in their identification. There exist certain online-based approaches, such as using Master Journal List provided by Thomson Reuters, and Scopus database, and using the DOI of a paper, to certify the realness of a journal or publisher. It is indispensable that inexperienced students and researchers know these methods so as to identify hijacked journals and publishers with a higher level of probability.

  19. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

    PubMed Central

    Sager, Jennifer E.; Yu, Jingjing; Ragueneau-Majlessi, Isabelle

    2015-01-01

    Modeling and simulation of drug disposition has emerged as an important tool in drug development, clinical study design and regulatory review, and the number of physiologically based pharmacokinetic (PBPK) modeling related publications and regulatory submissions have risen dramatically in recent years. However, the extent of use of PBPK modeling by researchers, and the public availability of models has not been systematically evaluated. This review evaluates PBPK-related publications to 1) identify the common applications of PBPK modeling; 2) determine ways in which models are developed; 3) establish how model quality is assessed; and 4) provide a list of publically available PBPK models for sensitive P450 and transporter substrates as well as selective inhibitors and inducers. PubMed searches were conducted using the terms “PBPK” and “physiologically based pharmacokinetic model” to collect published models. Only papers on PBPK modeling of pharmaceutical agents in humans published in English between 2008 and May 2015 were reviewed. A total of 366 PBPK-related articles met the search criteria, with the number of articles published per year rising steadily. Published models were most commonly used for drug-drug interaction predictions (28%), followed by interindividual variability and general clinical pharmacokinetic predictions (23%), formulation or absorption modeling (12%), and predicting age-related changes in pharmacokinetics and disposition (10%). In total, 106 models of sensitive substrates, inhibitors, and inducers were identified. An in-depth analysis of the model development and verification revealed a lack of consistency in model development and quality assessment practices, demonstrating a need for development of best-practice guidelines. PMID:26296709

  20. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification.

    PubMed

    Sager, Jennifer E; Yu, Jingjing; Ragueneau-Majlessi, Isabelle; Isoherranen, Nina

    2015-11-01

    Modeling and simulation of drug disposition has emerged as an important tool in drug development, clinical study design and regulatory review, and the number of physiologically based pharmacokinetic (PBPK) modeling related publications and regulatory submissions have risen dramatically in recent years. However, the extent of use of PBPK modeling by researchers, and the public availability of models has not been systematically evaluated. This review evaluates PBPK-related publications to 1) identify the common applications of PBPK modeling; 2) determine ways in which models are developed; 3) establish how model quality is assessed; and 4) provide a list of publically available PBPK models for sensitive P450 and transporter substrates as well as selective inhibitors and inducers. PubMed searches were conducted using the terms "PBPK" and "physiologically based pharmacokinetic model" to collect published models. Only papers on PBPK modeling of pharmaceutical agents in humans published in English between 2008 and May 2015 were reviewed. A total of 366 PBPK-related articles met the search criteria, with the number of articles published per year rising steadily. Published models were most commonly used for drug-drug interaction predictions (28%), followed by interindividual variability and general clinical pharmacokinetic predictions (23%), formulation or absorption modeling (12%), and predicting age-related changes in pharmacokinetics and disposition (10%). In total, 106 models of sensitive substrates, inhibitors, and inducers were identified. An in-depth analysis of the model development and verification revealed a lack of consistency in model development and quality assessment practices, demonstrating a need for development of best-practice guidelines.

  1. Publisher's Note: Search for the Rare Leptonic Decay B+→μ+νμ [ Phys. Rev. Lett. 92, 221803 (2004)

    NASA Astrophysics Data System (ADS)

    Aubert, B.; Barate, R.; Boutigny, D.; Couderc, F.; Gaillard, J.-M.; Hicheur, A.; Karyotakis, Y.; Lees, J. P.; Tisserand, V.; Zghiche, A.; Palano, A.; Pompili, A.; Chen, J. C.; Qi, N. D.; Rong, G.; Wang, P.; Zhu, Y. S.; Eigen, G.; Ofte, I.; Stugu, B.; Abrams, G. S.; Borgland, A. W.; Breon, A. B.; Brown, D. N.; Button-Shafer, J.; Cahn, R. N.; Charles, E.; Day, C. T.; Gill, M. S.; Gritsan, A. V.; Groysman, Y.; Jacobsen, R. G.; Kadel, R. W.; Kadyk, J.; Kerth, L. T.; Kolomensky, Yu. G.; Kukartsev, G.; Leclerc, C.; Levi, M. E.; Lynch, G.; Mir, L. M.; Oddone, P. J.; Orimoto, T. J.; Pripstein, M.; Roe, N. A.; Ronan, M. T.; Shelkov, V. G.; Telnov, A. V.; Wenzel, W. A.; Ford, K.; Harrison, T. J.; Hawkes, C. M.; Morgan, S. E.; Watson, A. T.; Watson, N. K.; Fritsch, M.; Goetzen, K.; Held, T.; Koch, H.; Lewandowski, B.; Pelizaeus, M.; Peters, K.; Schmuecker, H.; Steinke, M.; Boyd, J. T.; Chevalier, N.; Cottingham, W. N.; Kelly, M. P.; Latham, T. E.; Mackay, C.; Wilson, F. F.; Abe, K.; Cuhadar-Donszelmann, T.; Hearty, C.; Mattison, T. S.; McKenna, J. A.; Thiessen, D.; Kyberd, P.; McKemey, A. K.; Teodorescu, L.; Blinov, V. E.; Bukin, A. D.; Golubev, V. B.; Ivanchenko, V. N.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Yushkov, A. N.; Best, D.; Bruinsma, M.; Chao, M.; Eschrich, I.; Kirkby, D.; Lankford, A. J.; Mandelkern, M.; Mommsen, R. K.; Roethel, W.; Stoker, D. P.; Buchanan, C.; Hartfiel, B. L.; Gary, J. W.; Layter, J.; Shen, B. C.; Wang, K.; del Re, D.; Hadavand, H. K.; Hill, E. J.; Macfarlane, D. B.; Paar, H. P.; Rahatlou, Sh.; Sharma, V.; Berryhill, J. W.; Campagnari, C.; Dahmes, B.; Levy, S. L.; Long, O.; Lu, A.; Mazur, M. A.; Richman, J. D.; Verkerke, W.; Beck, T. W.; Beringer, J.; Eisner, A. M.; Heusch, C. A.; Lockman, W. S.; Schalk, T.; Schmitz, R. E.; Schumm, B. A.; Seiden, A.; Spradlin, P.; Walkowiak, W.; Williams, D. C.; Wilson, M. G.; Albert, J.; Chen, E.; Dubois-Felsmann, G. P.; Dvoretskii, A.; Erwin, R. J.; Hitlin, D. G.; Narsky, I.; Piatenko, T.; Porter, F. C.; Ryd, A.; Samuel, A.; Yang, S.; Jayatilleke, S.; Mancinelli, G.; Meadows, B. T.; Sokoloff, M. D.; Abe, T.; Blanc, F.; Bloom, P.; Chen, S.; Clark, P. J.; Ford, W. T.; Nauenberg, U.; Olivas, A.; Rankin, P.; Roy, J.; Smith, J. G.; van Hoek, W. C.; Zhang, L.; Harton, J. L.; Hu, T.; Soffer, A.; Toki, W. H.; Wilson, R. J.; Zhang, J.; Altenburg, D.; Brandt, T.; Brose, J.; Colberg, T.; Dickopp, M.; Feltresi, E.; Hauke, A.; Lacker, H. M.; Maly, E.; Müller-Pfefferkorn, R.; Nogowski, R.; Otto, S.; Schubert, J.; Schubert, K. R.; Schwierz, R.; Spaan, B.; Bernard, D.; Bonneaud, G. R.; Brochard, F.; Grenier, P.; Thiebaux, Ch.; Vasileiadis, G.; Verderi, M.; Bard, D. J.; Khan, A.; Lavin, D.; Muheim, F.; Playfer, S.; Andreotti, M.; Azzolini, V.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cibinnetto, G.; Luppi, E.; Negrini, M.; Piemontese, L.; Sarti, A.; Treadwell, E.; Baldini-Ferroli, R.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Patteri, P.; Piccolo, M.; Zallo, A.; Buzzo, A.; Capra, R.; Contri, R.; Crosetti, G.; Lo Vetere, M.; Macri, M.; Monge, M. R.; Passaggio, S.; Patrignani, C.; Robutti, E.; Santroni, A.; Tosi, S.; Bailey, S.; Morii, M.; Won, E.; Dubitzky, R. S.; Langenegger, U.; Bhimji, W.; Bowerman, D. A.; Dauncey, P. D.; Egede, U.; Gaillard, J. R.; Morton, G. W.; Nash, J. A.; Taylor, G. P.; Grenier, G. J.; Lee, S.-J.; Mallik, U.; Cochran, J.; Crawley, H. B.; Lamsa, J.; Meyer, W. T.; Prell, S.; Rosenberg, E. I.; Yi, J.; Davier, M.; Grosdidier, G.; Höcker, A.; Laplace, S.; Le Diberder, F.; Lepeltier, V.; Lutz, A. M.; Petersen, T. C.; Plaszczynski, S.; Schune, M. H.; Tantot, L.; Wormser, G.; Brigljević, V.; Cheng, C. H.; Lange, D. J.; Simani, M. C.; Wright, D. M.; Bevan, A. J.; Coleman, J. P.; Fry, J. R.; Gabathuler, E.; Gamet, R.; Kay, M.; Parry, R. J.; Payne, D. J.; Sloane, R. J.; Touramanis, C.; Back, J. J.; Harrison, P. F.; Mohanty, G. B.; Brown, C. L.; Cowan, G.; Flack, R. L.; Flaecher, H. U.; George, S.; Green, M. G.; Kurup, A.; Marker, C. E.; McMahon, T. R.; Ricciardi, S.; Salvatore, F.; Vaitsas, G.; Winter, M. A.; Brown, D.; Davis, C. L.; Allison, J.; Barlow, N. R.; Barlow, R. J.; Hart, P. A.; Hodgkinson, M. C.; Lafferty, G. D.; Lyon, A. J.; Williams, J. C.; Farbin, A.; Hulsbergen, W. D.; Jawahery, A.; Kovalskyi, D.; Lae, C. K.; Lillard, V.; Roberts, D. A.; Blaylock, G.; Dallapiccola, C.; Flood, K. T.; Hertzbach, S. S.; Kofler, R.; Koptchev, V. B.; Moore, T. B.; Saremi, S.; Staengle, H.; Willocq, S.; Cowan, R.; Sciolla, G.; Taylor, F.; Yamamoto, R. K.; Mangeol, D. J. J.; Patel, P. M.; Robertson, S. H.; Lazzaro, A.; Palombo, F.; Bauer, J. M.; Cremaldi, L.; Eschenburg, V.; Godang, R.; Kroeger, R.; Reidy, J.; Sanders, D. A.; Summers, D. J.; Zhao, H. W.; Brunet, S.; Cote-Ahern, D.; Taras, P.; Nicholson, H.; Cartaro, C.; Cavallo, N.; de Nardo, G.; Fabozzi, F.; Gatto, C.; Lista, L.; Paolucci, P.; Piccolo, D.; Sciacca, C.; Baak, M. A.; Raven, G.; Wilden, L.; Jessop, C. P.; Losecco, J. M.; Gabirel, T. A.; Allmmendinger, T.; Brau, B.; Gan, K. K.; Honscheid, K.; Hufnagel, D.; Kagan, H.; Kass, R.; Pulliam, T.; Ter-Antonyan, R.; Wong, Q. K.; Brau, J.; Frey, R.; Igonkina, O.; Potter, C. T.; Sinev, N. B.; Strom, D.; Torrence, E.; Colecchia, F.; Dorigo, A.; Galeazzi, F.; Margoni, M.; Morandin, M.; Posocco, M.; Rotondo, M.; Simonetto, F.; Stroli, R.; Tiozzo, G.; Voci, C.; Benayoun, M.; Briand, H.; Chauveau, J.; David, P.; de La Vaissière, Ch.; del Buono, L.; Hamon, O.; John, M. J. J.; Leruste, Ph.; Ocariz, J.; Pivk, M.; Roos, L.; T'jampens, S.; Therin, G.; Manfredi, P. F.; Re, V.; Behera, P. K.; Gladney, L.; Guo, Q. H.; Panetta, J.; Anulli, F.; Biasini, M.; Peruzzi, I. M.; Pioppi, M.; Angelini, C.; Batignani, G.; Bettarini, S.; Bondioli, M.; Bucci, F.; Calderini, G.; Carpinelli, M.; del Gamba, V.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Marchiori, G.; Martinez-Vidal, F.; Morganti, M.; Neri, N.; Paoloni, E.; Rama, M.; Rizzo, G.; Sandrelli, F.; Walsh, J.; Haire, M.; Hudd, D.; Paick, K.; Wagoner, D. E.; Danielson, N.; Elmer, P.; Lu, C.; Miftakov, V.; Olsen, J.; Smith, A. J. S.; Varnes, E. W.; Bellini, F.; Cavoto, G.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Gaspero, M.; Mazzoni, M. A.; Morganti, S.; Pierini, M.; Piredda, G.; Safai Tehrani, F.; Voena, C.; Christ, S.; Wagner, G.; Waldi, R.; Adye, T.; de Groot, N.; Franek, B.; Geddes, N. I.; Gopal, G. P.; Olaiya, E. O.; Xella, S. M.; Aleksan, R.; Emery, S.; Gaidot, A.; Ganzhur, S. F.; Giraud, P.-F.; Hamel de Monchenault, G.; Kozanecki, W.; Langer, M.; Legendre, M.; London, G. W.; Mayer, B.; Schott, G.; Vasseur, G.; Yeche, Ch.; Zito, M.; Purohit, M. V.; Weidemann, A. W.; Yumiceva, F. X.; Aston, D.; Bartoldus, R.; Berger, N.; Boyarski, A. M.; Buchmueller, O. L.; Convery, M. R.; Cristinziani, M.; Dong, D.; Dorfan, J.; Dujmic, D.; Dunwoodie, W.; Elsen, E. E.; Field, R. C.; Glanzman, T.; Gowdy, S. J.; Hadig, T.; Holyo, V.; Hryn'ova, T.; Innes, W. R.; Kelsey, M. H.; Kim, P.; Kocian, M. L.; Leith, D. W. G. S.; Libby, J.; Luitz, S.; Luth, V.; Lynch, H. L.; Marsiske, H.; Messner, R.; Muller, D. R.; O'Grady, C. P.; Ozcan, V. E.; Perazzo, A.; Perl, M.; Petrak, S.; Ratcliff, B. N.; Roodman, A.; Salnikov, A. A.; Schindler, R. H.; Schwiening, J.; Simi, G.; Snyder, A.; Soha, A.; Stelzer, J.; Su, D.; Sullivan, M. K.; Va'Vra, J.; Wagner, S. R.; Weaver, M.; Weinstein, A. J. R.; Wisniewski, W. J.; Wright, D. H.; Young, C. C.; Buchat, P. R.; Edwards, A. J.; Meyer, T. I.; Peterson, B. A.; Roat, C.; Ahmed, M.; Ahmed, S.; Alam, M. S.; Ernst, J. A.; Saeed, M. A.; Saleem, M.; Wappler, F. R.; Bugg, W.; Krishnamurthy, M.; Spanier, S. M.; Eckmann, R.; Kim, H.; Ritchie, J. L.; Satpathy, A.; Schwitters, R. F.; Izen, J. M.; Kitayama, I.; Lou, X. C.; Ye, S.; Bianchi, F.; Bona, M.; Gallo, F.; Gamba, D.; Borean, C.; Bosisio, L.; Cossutti, F.; della Ricca, G.; Dittongo, S.; Grancagnolo, S.; Lanceri, L.; Poropat, P.; Vitale, L.; Vuagnin, G.; Panvini, R. S.; Banerjee, Sw.; Brown, C. M.; Fortin, D.; Jackson, P. D.; Kowalewski, R.; Roney, J. M.; Band, H. R.; Dasu, S.; Datta, M.; Eichenbaum, A. M.; Johnson, J. R.; Kutter, P. E.; Li, H.; Liu, R.; di Lodovico, F.; Mihalyi, A.; Mohapatra, A. K.; Pan, Y.; Prepost, R.; Sekula, S. J.; von Wimmersperg-Toeller, J. H.; Wu, J.; Wu, S. L.; Yu, Z.; Neal, H.

    2004-10-01

    We have performed a search for the rare leptonic decay B+ --> mu+ nu_mu with data collected at the Upsilon(4S) resonance by the BABAR experiment at the PEP-II storage ring. In a sample of 88.4 million BBbar pairs, we find no significant evidence for a signal and set an upper limit on the branching fraction BR(B+ --> mu+ nu_mu) < 6.6 x 10^{-6} at the 90% confidence level.

  2. A Query-Based Approach in Web Search Instruction: An Assessment of Current Practice

    ERIC Educational Resources Information Center

    Cohen, Laura B.

    2005-01-01

    An instruction program that covers search tools on the Web should incorporate a user's information need as the basis for teaching these tools. This article lays the theoretical groundwork for such a query-based approach, deriving its argument from the literature published in the early days of databases in libraries. A review of recent literature…

  3. Evaluating medical student searches of MEDLINE for evidence-based information: process and application of results.

    PubMed

    Burrows, S C; Tylman, V

    1999-10-01

    To evaluate the adequacy of the MEDLINE instruction routinely given to all entering medical students at the University of Miami School of Medicine and the ability of students to search effectively for and retrieve evidence-based information for clinical decision making by the end of their third-year. The authors developed and implemented a strategy for evaluating the search strategies and articles selected by third-year students, who participated in the Objective Structured Clinical Examination (OSCE) in June 1996, 1997, and 1998, and reviewed the literature on evidence-based medicine and evaluation of medical student searches. A mean of 5% of the students' search strategies and a mean of 26% of articles selected were ranked "excellent" or "good"; a mean of 26% of search strategies were ranked "fair" and a mean of 69% were ranked "poor"; and a mean of 22% of articles selected were ranked "fair" and a mean of 52% were ranked "poor" based on the strategy developed to evaluate student searches. Evaluating medical student searches for evidence-based information is an effective way of evaluating students' searching proficiency, and, in turn, the adequacy of the instruction they receive. Based on the results of the OSCE test, the school of medicine expanded the library's educational role and the library implemented major changes in the training program. Information on evidence-based medicine is now incorporated into the MEDLINE instruction. Library faculty evaluate the required searches performed by students for evidence-based information during their first and second years; 30% of students are identified for follow-up, individualized instruction based on the evaluation; and a new case-based curriculum has been proposed with a fourteen-week problem-based learning (PBL) block. These developments are timely in light of the evidence-based competencies recently published by the Association of American Medical Colleges.

  4. Evaluating medical student searches of MEDLINE for evidence-based information: process and application of results.

    PubMed Central

    Burrows, S C; Tylman, V

    1999-01-01

    OBJECTIVE: To evaluate the adequacy of the MEDLINE instruction routinely given to all entering medical students at the University of Miami School of Medicine and the ability of students to search effectively for and retrieve evidence-based information for clinical decision making by the end of their third-year. METHODOLOGY: The authors developed and implemented a strategy for evaluating the search strategies and articles selected by third-year students, who participated in the Objective Structured Clinical Examination (OSCE) in June 1996, 1997, and 1998, and reviewed the literature on evidence-based medicine and evaluation of medical student searches. RESULTS: A mean of 5% of the students' search strategies and a mean of 26% of articles selected were ranked "excellent" or "good"; a mean of 26% of search strategies were ranked "fair" and a mean of 69% were ranked "poor"; and a mean of 22% of articles selected were ranked "fair" and a mean of 52% were ranked "poor" based on the strategy developed to evaluate student searches. CONCLUSIONS: Evaluating medical student searches for evidence-based information is an effective way of evaluating students' searching proficiency, and, in turn, the adequacy of the instruction they receive. Based on the results of the OSCE test, the school of medicine expanded the library's educational role and the library implemented major changes in the training program. Information on evidence-based medicine is now incorporated into the MEDLINE instruction. Library faculty evaluate the required searches performed by students for evidence-based information during their first and second years; 30% of students are identified for follow-up, individualized instruction based on the evaluation; and a new case-based curriculum has been proposed with a fourteen-week problem-based learning (PBL) block. These developments are timely in light of the evidence-based competencies recently published by the Association of American Medical Colleges. PMID

  5. Publisher's note Publisher's note

    NASA Astrophysics Data System (ADS)

    Malloy, Andrew

    2012-06-01

    Due to an error in the production process, an incorrect version of the article by Margaritis Voliotis et al 2012 Phys. Biol. 9 036002 was published on 3 May 2012. IOP Publishing apologizes for this error. This version of the article has now been superseded by a new version published on 29 May 2012 with the article reference Margaritis Voliotis et al 2012 Phys. Biol. 9 036007.

  6. Spaced-based search coil magnetometers

    NASA Astrophysics Data System (ADS)

    Hospodarsky, George B.

    2016-12-01

    Search coil magnetometers are one of the primary tools used to study the magnetic component of low-frequency electromagnetic waves in space. Their relatively small size, mass, and power consumption, coupled with a good frequency range and sensitivity, make them ideal for spaceflight applications. The basic design of a search coil magnetometer consists of many thousands of turns of wire wound on a high permeability core. When a time-varying magnetic field passes through the coil, a time-varying voltage is induced due to Faraday's law of magnetic induction. The output of the coil is usually attached to a preamplifier, which amplifies the induced voltage and conditions the signal for transmission to the main electronics (usually a low-frequency radio receiver). Search coil magnetometers are usually used in conjunction with electric field antenna to measure electromagnetic plasma waves in the frequency range of a few hertz to a few tens of kilohertzs. Search coil magnetometers are used to determine the properties of waves, such as comparing the relative electric and magnetic field amplitudes of the waves, or to investigate wave propagation parameters, such as Poynting flux and wave normal vectors. On a spinning spacecraft, they are also sometimes used to determine the background magnetic field. This paper presents some of the basic design criteria of search coil magnetometers and discusses design characteristics of sensors flown on a number of spacecraft.

  7. Broad-Based Search for New and Practical Superconductors

    DTIC Science & Technology

    2014-10-31

    dielectric metamaterial has been tested in experiments with compressed mixtures of tin and barium titanate (BTO) and strontium titanate(STO) nanoparticles...work is published in Phys. Rev. B 89 , 134516 (2014). 3. New/Unexplored Directions: Search for Superconductivity in Naturally Occurring Mineral

  8. Leaky Pipeline Myths: In Search of Gender Effects on the Job Market and Early Career Publishing in Philosophy.

    PubMed

    Allen-Hermanson, Sean

    2017-01-01

    That philosophy is an outlier in the humanities when it comes to the underrepresentation of women has been the occasion for much discussion about possible effects of subtle forms of prejudice, including implicit bias and stereotype threat. While these ideas have become familiar to the philosophical community, there has only recently been a surge of interest in acquiring field-specific data. This paper adds to quantitative findings bearing on hypotheses about the effects of unconscious prejudice on two important stages along career pathways: tenure-track hiring and early career publishing.

  9. Leaky Pipeline Myths: In Search of Gender Effects on the Job Market and Early Career Publishing in Philosophy

    PubMed Central

    Allen-Hermanson, Sean

    2017-01-01

    That philosophy is an outlier in the humanities when it comes to the underrepresentation of women has been the occasion for much discussion about possible effects of subtle forms of prejudice, including implicit bias and stereotype threat. While these ideas have become familiar to the philosophical community, there has only recently been a surge of interest in acquiring field-specific data. This paper adds to quantitative findings bearing on hypotheses about the effects of unconscious prejudice on two important stages along career pathways: tenure-track hiring and early career publishing. PMID:28659843

  10. Archetype based search in an IHE XDS environment.

    PubMed

    Rinner, Christoph; Kohler, Michael; Hübner-Bloder, Gudrun; Saboor, Samrend; Ammenwerth, Elske; Duftschmid, Georg

    2012-01-01

    To prevent information overload of physicians when accessing EHRs we introduce a method to extend the IHE XDS profile metadata-based search towards a content-based search. Detailed queries are created based on predefined information needs mapped to ISO/EN 13606 Archetypes. They are aggregated to a metadata-based query to retrieve all relevant documents, which are then analyzed for the desired contents. The results are presented in a tabular form. The content-based search in IHE-XDS could be implemented efficiently and was found helpful by the evaluating physicians.

  11. Attribute-Based Proxy Re-Encryption with Keyword Search

    PubMed Central

    Shi, Yanfeng; Liu, Jiqiang; Han, Zhen; Zheng, Qingji; Zhang, Rui; Qiu, Shuo

    2014-01-01

    Keyword search on encrypted data allows one to issue the search token and conduct search operations on encrypted data while still preserving keyword privacy. In the present paper, we consider the keyword search problem further and introduce a novel notion called attribute-based proxy re-encryption with keyword search (), which introduces a promising feature: In addition to supporting keyword search on encrypted data, it enables data owners to delegate the keyword search capability to some other data users complying with the specific access control policy. To be specific, allows (i) the data owner to outsource his encrypted data to the cloud and then ask the cloud to conduct keyword search on outsourced encrypted data with the given search token, and (ii) the data owner to delegate other data users keyword search capability in the fine-grained access control manner through allowing the cloud to re-encrypted stored encrypted data with a re-encrypted data (embedding with some form of access control policy). We formalize the syntax and security definitions for , and propose two concrete constructions for : key-policy and ciphertext-policy . In the nutshell, our constructions can be treated as the integration of technologies in the fields of attribute-based cryptography and proxy re-encryption cryptography. PMID:25549257

  12. Attribute-based proxy re-encryption with keyword search.

    PubMed

    Shi, Yanfeng; Liu, Jiqiang; Han, Zhen; Zheng, Qingji; Zhang, Rui; Qiu, Shuo

    2014-01-01

    Keyword search on encrypted data allows one to issue the search token and conduct search operations on encrypted data while still preserving keyword privacy. In the present paper, we consider the keyword search problem further and introduce a novel notion called attribute-based proxy re-encryption with keyword search (ABRKS), which introduces a promising feature: In addition to supporting keyword search on encrypted data, it enables data owners to delegate the keyword search capability to some other data users complying with the specific access control policy. To be specific, ABRKS allows (i) the data owner to outsource his encrypted data to the cloud and then ask the cloud to conduct keyword search on outsourced encrypted data with the given search token, and (ii) the data owner to delegate other data users keyword search capability in the fine-grained access control manner through allowing the cloud to re-encrypted stored encrypted data with a re-encrypted data (embedding with some form of access control policy). We formalize the syntax and security definitions for ABRKS, and propose two concrete constructions for ABRKS: key-policy ABRKS and ciphertext-policy ABRKS. In the nutshell, our constructions can be treated as the integration of technologies in the fields of attribute-based cryptography and proxy re-encryption cryptography.

  13. Novel citation-based search method for scientific literature: application to meta-analyses.

    PubMed

    Janssens, A Cecile J W; Gwinn, M

    2015-10-13

    Finding eligible studies for meta-analysis and systematic reviews relies on keyword-based searching as the gold standard, despite its inefficiency. Searching based on direct citations is not sufficiently comprehensive. We propose a novel strategy that ranks articles on their degree of co-citation with one or more "known" articles before reviewing their eligibility. In two independent studies, we aimed to reproduce the results of literature searches for sets of published meta-analyses (n = 10 and n = 42). For each meta-analysis, we extracted co-citations for the randomly selected 'known' articles from the Web of Science database, counted their frequencies and screened all articles with a score above a selection threshold. In the second study, we extended the method by retrieving direct citations for all selected articles. In the first study, we retrieved 82% of the studies included in the meta-analyses while screening only 11% as many articles as were screened for the original publications. Articles that we missed were published in non-English languages, published before 1975, published very recently, or available only as conference abstracts. In the second study, we retrieved 79% of included studies while screening half the original number of articles. Citation searching appears to be an efficient and reasonably accurate method for finding articles similar to one or more articles of interest for meta-analysis and reviews.

  14. Eye-Search: A web-based therapy that improves visual search in hemianopia

    PubMed Central

    Ong, Yean-Hoon; Jacquin-Courtois, Sophie; Gorgoraptis, Nikos; Bays, Paul M; Husain, Masud; Leff, Alexander P

    2015-01-01

    Persisting hemianopia frequently complicates lesions of the posterior cerebral hemispheres, leaving patients impaired on a range of key activities of daily living. Practice-based therapies designed to induce compensatory eye movements can improve hemianopic patients' visual function, but are not readily available. We used a web-based therapy (Eye-Search) that retrains visual search saccades into patients' blind hemifield. A group of 78 suitable hemianopic patients took part. After therapy (800 trials over 11 days), search times into their impaired hemifield improved by an average of 24%. Patients also reported improvements in a subset of visually guided everyday activities, suggesting that Eye-Search therapy affects real-world outcomes. PMID:25642437

  15. GeNemo: a search engine for web-based functional genomic data.

    PubMed

    Zhang, Yongqing; Cao, Xiaoyi; Zhong, Sheng

    2016-07-08

    A set of new data types emerged from functional genomic assays, including ChIP-seq, DNase-seq, FAIRE-seq and others. The results are typically stored as genome-wide intensities (WIG/bigWig files) or functional genomic regions (peak/BED files). These data types present new challenges to big data science. Here, we present GeNemo, a web-based search engine for functional genomic data. GeNemo searches user-input data against online functional genomic datasets, including the entire collection of ENCODE and mouse ENCODE datasets. Unlike text-based search engines, GeNemo's searches are based on pattern matching of functional genomic regions. This distinguishes GeNemo from text or DNA sequence searches. The user can input any complete or partial functional genomic dataset, for example, a binding intensity file (bigWig) or a peak file. GeNemo reports any genomic regions, ranging from hundred bases to hundred thousand bases, from any of the online ENCODE datasets that share similar functional (binding, modification, accessibility) patterns. This is enabled by a Markov Chain Monte Carlo-based maximization process, executed on up to 24 parallel computing threads. By clicking on a search result, the user can visually compare her/his data with the found datasets and navigate the identified genomic regions. GeNemo is available at www.genemo.org. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. An Impact-Based Filtering Approach for Literature Searches

    ERIC Educational Resources Information Center

    Vista, Alvin

    2013-01-01

    This paper aims to present an alternative and simple method to improve the filtering of search results so as to increase the efficiency of literature searches, particularly for individual researchers who have limited logistical resources. The method proposed here is scope restriction using an impact-based filter, made possible by the emergence of…

  17. An Impact-Based Filtering Approach for Literature Searches

    ERIC Educational Resources Information Center

    Vista, Alvin

    2013-01-01

    This paper aims to present an alternative and simple method to improve the filtering of search results so as to increase the efficiency of literature searches, particularly for individual researchers who have limited logistical resources. The method proposed here is scope restriction using an impact-based filter, made possible by the emergence of…

  18. Random search optimization based on genetic algorithm and discriminant function

    NASA Technical Reports Server (NTRS)

    Kiciman, M. O.; Akgul, M.; Erarslanoglu, G.

    1990-01-01

    The general problem of optimization with arbitrary merit and constraint functions, which could be convex, concave, monotonic, or non-monotonic, is treated using stochastic methods. To improve the efficiency of the random search methods, a genetic algorithm for the search phase and a discriminant function for the constraint-control phase were utilized. The validity of the technique is demonstrated by comparing the results to published test problem results. Numerical experimentation indicated that for cases where a quick near optimum solution is desired, a general, user-friendly optimization code can be developed without serious penalties in both total computer time and accuracy.

  19. Random search optimization based on genetic algorithm and discriminant function

    NASA Technical Reports Server (NTRS)

    Kiciman, M. O.; Akgul, M.; Erarslanoglu, G.

    1990-01-01

    The general problem of optimization with arbitrary merit and constraint functions, which could be convex, concave, monotonic, or non-monotonic, is treated using stochastic methods. To improve the efficiency of the random search methods, a genetic algorithm for the search phase and a discriminant function for the constraint-control phase were utilized. The validity of the technique is demonstrated by comparing the results to published test problem results. Numerical experimentation indicated that for cases where a quick near optimum solution is desired, a general, user-friendly optimization code can be developed without serious penalties in both total computer time and accuracy.

  20. LAHS: A novel harmony search algorithm based on learning automata

    NASA Astrophysics Data System (ADS)

    Enayatifar, Rasul; Yousefi, Moslem; Abdullah, Abdul Hanan; Darus, Amer Nordin

    2013-12-01

    This study presents a learning automata-based harmony search (LAHS) for unconstrained optimization of continuous problems. The harmony search (HS) algorithm performance strongly depends on the fine tuning of its parameters, including the harmony consideration rate (HMCR), pitch adjustment rate (PAR) and bandwidth (bw). Inspired by the spur-in-time responses in the musical improvisation process, learning capabilities are employed in the HS to select these parameters based on spontaneous reactions. An extensive numerical investigation is conducted on several well-known test functions, and the results are compared with the HS algorithm and its prominent variants, including the improved harmony search (IHS), global-best harmony search (GHS) and self-adaptive global-best harmony search (SGHS). The numerical results indicate that the LAHS is more efficient in finding optimum solutions and outperforms the existing HS algorithm variants.

  1. Anion exchange resins: Structure, formulation, and applications. (Latest citations from the Rubber and Plastics Research Association database). Published Search

    SciTech Connect

    Not Available

    1994-07-01

    The bibliography contains citations concerning the formulation and synthesis of anion exchange resins based on such resins as amides, polyethylenes, and styrenes. Osmotic, sorption, and electrical properties; exchange kinetics behavior; structure studies; and temperature related performance effects on anion exchange resins are considered. Anion exchange chromatography of liquids, and applications in water purification, pollution control, and protein and metallic ion separation are included. (Contains a minimum of 222 citations and includes a subject term index and title list.)

  2. Development of Health Information Search Engine Based on Metadata and Ontology

    PubMed Central

    Song, Tae-Min; Jin, Dal-Lae

    2014-01-01

    Objectives The aim of the study was to develop a metadata and ontology-based health information search engine ensuring semantic interoperability to collect and provide health information using different application programs. Methods Health information metadata ontology was developed using a distributed semantic Web content publishing model based on vocabularies used to index the contents generated by the information producers as well as those used to search the contents by the users. Vocabulary for health information ontology was mapped to the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT), and a list of about 1,500 terms was proposed. The metadata schema used in this study was developed by adding an element describing the target audience to the Dublin Core Metadata Element Set. Results A metadata schema and an ontology ensuring interoperability of health information available on the internet were developed. The metadata and ontology-based health information search engine developed in this study produced a better search result compared to existing search engines. Conclusions Health information search engine based on metadata and ontology will provide reliable health information to both information producer and information consumers. PMID:24872907

  3. Development of health information search engine based on metadata and ontology.

    PubMed

    Song, Tae-Min; Park, Hyeoun-Ae; Jin, Dal-Lae

    2014-04-01

    The aim of the study was to develop a metadata and ontology-based health information search engine ensuring semantic interoperability to collect and provide health information using different application programs. Health information metadata ontology was developed using a distributed semantic Web content publishing model based on vocabularies used to index the contents generated by the information producers as well as those used to search the contents by the users. Vocabulary for health information ontology was mapped to the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT), and a list of about 1,500 terms was proposed. The metadata schema used in this study was developed by adding an element describing the target audience to the Dublin Core Metadata Element Set. A metadata schema and an ontology ensuring interoperability of health information available on the internet were developed. The metadata and ontology-based health information search engine developed in this study produced a better search result compared to existing search engines. Health information search engine based on metadata and ontology will provide reliable health information to both information producer and information consumers.

  4. Evidence-based librarianship: searching for the needed EBL evidence.

    PubMed

    Eldredge, J D

    2000-01-01

    This paper discusses the challenges of finding evidence needed to implement Evidence-Based Librarianship (EBL). Focusing first on database coverage for three health sciences librarianship journals, the article examines the information contents of different databases. Strategies are needed to search for relevant evidence in the library literature via these databases, and the problems associated with searching the grey literature of librarianship. Database coverage, plausible search strategies, and the grey literature of library science all pose challenges to finding the needed research evidence for practicing EBL. Health sciences librarians need to ensure that systems are designed that can track and provide access to needed research evidence to support Evidence-Based Librarianship (EBL).

  5. Toward a definition of competency-based education in medicine: a systematic review of published definitions.

    PubMed

    Frank, Jason R; Mungroo, Rani; Ahmad, Yasmine; Wang, Mimi; De Rossi, Stefanie; Horsley, Tanya

    2010-01-01

    Competency-based education (CBE) has emerged in the health professions to address criticisms of contemporary approaches to training. However, the literature has no clear, widely accepted definition of CBE that furthers innovation, debate, and scholarship in this area. To systematically review CBE-related literature in order to identify key terms and constructs to inform the development of a useful working definition of CBE for medical education. We searched electronic databases and supplemented searches by using authors' files, checking reference lists, contacting relevant organizations and conducting Internet searches. Screening was carried out by duplicate assessment, and disagreements were resolved by consensus. We included any English- or French-language sources that defined competency-based education. Data were analyzed qualitatively and summarized descriptively. We identified 15,956 records for initial relevancy screening by title and abstract. The full text of 1,826 records was then retrieved and assessed further for relevance. A total of 173 records were analyzed. We identified 4 major themes (organizing framework, rationale, contrast with time, and implementing CBE) and 6 sub-themes (outcomes defined, curriculum of competencies, demonstrable, assessment, learner-centred and societal needs). From these themes, a new definition of CBE was synthesized. This is the first comprehensive systematic review of the medical education literature related to CBE definitions. The themes and definition identified should be considered by educators to advance the field.

  6. The OGC Publish/Subscribe specification in the context of sensor-based applications

    NASA Astrophysics Data System (ADS)

    Bigagli, Lorenzo

    2014-05-01

    The Open Geospatial Consortium Publish/Subscribe Standards Working Group (in short, OGC PubSub SWG) was chartered in 2010 to specify a mechanism to support publish/subscribe requirements across OGC service interfaces and data types (coverage, feature, etc.) The Publish/Subscribe Interface Standard 1.0 - Core (13-131) defines an abstract description of the basic mandatory functionality, along with several optional, extended capabilities. The Core is independent of the underlying binding, for which two extensions are currently considered in the PubSub SWG scope: a SOAP binding and RESTful binding. Two primary parties characterize the publish/subscribe model: a Publisher, which is publishing information, and a Subscriber, which expresses an interest in all or part of the published information. In many cases, the Subscriber and the entity to which data is to be delivered (the Receiver) are one and the same. However, they are distinguished in PubSub to allow for these roles to be segregated. This is useful, for example, in event-based systems, where system entities primarily react to incoming information and may emit new information to other interested entities. The Publish/Subscribe model is distinguished from the typical request/response model, where a client makes a request and the server responds with either the requested information or a failure. This provides relatively immediate feedback, but can be insufficient in cases where the client is waiting for a specific event (such as data arrival, server changes, or data updates). In fact, while waiting for an event, a client must repeatedly request the desired information (polling). This has undesirable side effects: if a client polls frequently this can increase server load and network traffic, and if a client polls infrequently it may not receive a message when it is needed. These issues are accentuated when event occurrences are unpredictable, or when the delay between event occurrence and client notification must

  7. A unified architecture for biomedical search engines based on semantic web technologies.

    PubMed

    Jalali, Vahid; Matash Borujerdi, Mohammad Reza

    2011-04-01

    There is a huge growth in the volume of published biomedical research in recent years. Many medical search engines are designed and developed to address the over growing information needs of biomedical experts and curators. Significant progress has been made in utilizing the knowledge embedded in medical ontologies and controlled vocabularies to assist these engines. However, the lack of common architecture for utilized ontologies and overall retrieval process, hampers evaluating different search engines and interoperability between them under unified conditions. In this paper, a unified architecture for medical search engines is introduced. Proposed model contains standard schemas declared in semantic web languages for ontologies and documents used by search engines. Unified models for annotation and retrieval processes are other parts of introduced architecture. A sample search engine is also designed and implemented based on the proposed architecture in this paper. The search engine is evaluated using two test collections and results are reported in terms of precision vs. recall and mean average precision for different approaches used by this search engine.

  8. Search for chalcogenide based superconductors: Sulfur based solution growth

    NASA Astrophysics Data System (ADS)

    Kaluarachchi, Udhara; Bud'Ko, Sergey; Canfield, Paul

    2013-03-01

    As part of our effort to develop tools for searching for new chalcogenide based superconductors we are expanding the range of S-based binary melts that we can use for solution growth of single crystals. As a recent example, we have been able to grow single crystals of Rh17S15 and separate them for excess binary melt via high temperature decanting. In addition to refining the details of the Rh-S binary phase diagram, microscopic, thermodynamic and transport measurement on Rh17S15 crystals confirm their Tc ~ 5.5 K as well as their remarkably large Hc2(T) behavior. The possible cause of the enhanced Hc2(T) will be discussed. As time allows we will also review other S-based growths and compounds. This work was supported by AFOSR-MURI grant FA9550-09-1-0603 (UK and PCC) and by US DOE under the Contract No. DE-AC02-07CH11358 (SLB).

  9. A web-based rapid assessment tool for production publishing solutions

    NASA Astrophysics Data System (ADS)

    Sun, Tong

    2010-02-01

    Solution assessment is a critical first-step in understanding and measuring the business process efficiency enabled by an integrated solution package. However, assessing the effectiveness of any solution is usually a very expensive and timeconsuming task which involves lots of domain knowledge, collecting and understanding the specific customer operational context, defining validation scenarios and estimating the expected performance and operational cost. This paper presents an intelligent web-based tool that can rapidly assess any given solution package for production publishing workflows via a simulation engine and create a report for various estimated performance metrics (e.g. throughput, turnaround time, resource utilization) and operational cost. By integrating the digital publishing workflow ontology and an activity based costing model with a Petri-net based workflow simulation engine, this web-based tool allows users to quickly evaluate any potential digital publishing solutions side-by-side within their desired operational contexts, and provides a low-cost and rapid assessment for organizations before committing any purchase. This tool also benefits the solution providers to shorten the sales cycles, establishing a trustworthy customer relationship and supplement the professional assessment services with a proven quantitative simulation and estimation technology.

  10. Text-based plagiarism in scientific publishing: issues, developments and education.

    PubMed

    Li, Yongyan

    2013-09-01

    Text-based plagiarism, or copying language from sources, has recently become an issue of growing concern in scientific publishing. Use of CrossCheck (a computational text-matching tool) by journals has sometimes exposed an unexpected amount of textual similarity between submissions and databases of scholarly literature. In this paper I provide an overview of the relevant literature, to examine how journal gatekeepers perceive textual appropriation, and how automated plagiarism-screening tools have been developed to detect text matching, with the technique now available for self-check of manuscripts before submission; I also discuss issues around English as an additional language (EAL) authors and in particular EAL novices being the typical offenders of textual borrowing. The final section of the paper proposes a few educational directions to take in tackling text-based plagiarism, highlighting the roles of the publishing industry, senior authors and English for academic purposes professionals.

  11. [Evidence-based practices published in Brazil: identification and analysis studies about human health prevention].

    PubMed

    Lacerda, Rúbia Aparecida; Egry, Emiko Yoshikawa; da Fonseca, Rosa Maria Godoy Serpa; Lopes, Nadir Aparecida; Nunes, Bruna Kosar; Batista, Arlete de Oliveira; Graziano, Kazuko Uchikawa; Angelo, Margareth; Januário, Maria Madalena Leite; Merighi, Miriam Aparecida Barbosa; Castilho, Valéria

    2012-10-01

    Integrative review of Brazilian studies about evidence-based practices (EBP) about prevention in human health, published in Web of Science/JCR journals, between October 2010 and April 2011. The aim was to identify the specialties that most accomplished these studies, their foci and methodological approaches. Based on inclusion criteria, 84 studies were selected, mainly published in public health journals, focusing on primary care and also addressing clinical issues and different specialties. Prevention foci and methodological approaches also varied, with a predominance of systematic reviews without meta-analysis. The results indicate that there is no single way to conceptualize and practice EBP in the field of prevention, and that its application may not only serve to obtain indisputable evidence to equip intervention actions. This endless knowledge area is under construction, with a view to the analysis and further understanding of health phenomena.

  12. Realizing IoT service's policy privacy over publish/subscribe-based middleware.

    PubMed

    Duan, Li; Zhang, Yang; Chen, Shiping; Wang, Shiyao; Cheng, Bo; Chen, Junliang

    2016-01-01

    The publish/subscribe paradigm makes IoT service collaborations more scalable and flexible, due to the space, time and control decoupling of event producers and consumers. Thus, the paradigm can be used to establish large-scale IoT service communication infrastructures such as Supervisory Control and Data Acquisition systems. However, preserving IoT service's policy privacy is difficult in this paradigm, because a classical publisher has little control of its own event after being published; and a subscriber has to accept all the events from the subscribed event type with no choice. Few existing publish/subscribe middleware have built-in mechanisms to address the above issues. In this paper, we present a novel access control framework, which is capable of preserving IoT service's policy privacy. In particular, we adopt the publish/subscribe paradigm as the IoT service communication infrastructure to facilitate the protection of IoT services policy privacy. The key idea in our policy-privacy solution is using a two-layer cooperating method to match bi-directional privacy control requirements: (a) data layer for protecting IoT events; and (b) application layer for preserving the privacy of service policy. Furthermore, the anonymous-set-based principle is adopted to realize the functionalities of the framework, including policy embedding and policy encoding as well as policy matching. Our security analysis shows that the policy privacy framework is Chosen-Plaintext Attack secure. We extend the open source Apache ActiveMQ broker by building into a policy-based authorization mechanism to enforce the privacy policy. The performance evaluation results indicate that our approach is scalable with reasonable overheads.

  13. In Search of...Brain-Based Education.

    ERIC Educational Resources Information Center

    Bruer, John T.

    1999-01-01

    Debunks two ideas appearing in brain-based education articles: the educational significance of brain laterality (right brain versus left brain) and claims for a sensitive period of brain development in young children. Brain-based education literature provides a popular but misleading mix of fact, misinterpretation, and fantasy. (47 references (MLH)

  14. In Search of...Brain-Based Education.

    ERIC Educational Resources Information Center

    Bruer, John T.

    1999-01-01

    Debunks two ideas appearing in brain-based education articles: the educational significance of brain laterality (right brain versus left brain) and claims for a sensitive period of brain development in young children. Brain-based education literature provides a popular but misleading mix of fact, misinterpretation, and fantasy. (47 references (MLH)

  15. Dredging: Technology and environmental aspects. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning the technology and environmental impacts of dredging. Equipment, including semi-submersible cutter platforms, is described. Other topics include sediment movement, factors affecting sediment movement, the disposal of dredged material, and computer models predicting the fate of the dredged materials. The environmental impacts of the dredged areas and the effects of ocean dumping of dredged material are also discussed. (Contains 250 citations and includes a subject term index and title list.)

  16. Hazardous materials: Microbiological decomposition. (lLtest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the decomposition of toxic materials by biological means. Bacteria, enzymes, and bioluminescence are among the methods discussed. Bacteria and enzymes that digest toluene, polychlorinated biphenyls (PCBs), selenium wastes, oil shale waste, uranium, oil sludge, pesticides, rubber wastes, and pentachlorophenol are discussed. Flavobacterium and white rot fungus are among the biological agents highlighted. (Contains 250 citations and includes a subject term index and title list.)

  17. Militarization of space. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning existing and projected military use of space by the United States and foreign powers. Long term strategies, technical feasibility studies, and the use of space in tactical operations are considered. Space weapons, including high-energy lasers, shuttle operations, and the Strategic Defense Initiative (SDI) program are examined. (Contains 250 citations and includes a subject term index and title list.)

  18. Human gene therapy: methods and materials. (latest citations from the biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning the evolution of technologies for genetic identification and treatment of diseases such as cancer, immune deficiencies, anemias, hemophilias, muscular dystrophy, and diabetes. Emphasis is placed upon development and application of genetic engineering techniques for the production of medicinal biological preparations. Other topics include the use of DNA (deoxyribonucleic acid) probes for gene isolation and disease marker identification, methods for replacing missing or defective genetic material, and mapping of the human genome. Governmental regulation, and moral and ethical implications are briefly reviewed. (Contains 250 citations and includes a subject term index and title list.)

  19. Centrifuge enrichment plants. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the design, control, monitoring, and safety of centrifuge enrichment plants. Power supplies, enrichment plant safeguards, facility design, cascade heater test loops to monitor the enrichment process, inspection strategies, and the socioeconomic effects of centrifuge enrichment plants are examined. Radioactive waste disposal problems are briefly considered. (Contains a minimum of 169 citations and includes a subject term index and title list.)

  20. Carbon monoxide toxicity. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the mechanism and clinical manifestations of carbon monoxide (CO) exposure, including the effects on the liver, cardiovascular, and nervous systems. Topics include studies of the carbon monoxide binding affinity with hemoglobin, measurement of carboxyhemoglobin in humans and various animal species, carbon monoxide levels resulting from tobacco and marijuana smoke, occupational exposure and the NIOSH (National Institute for Occupational Safety and Health) biological exposure index, symptomology and percent of blood CO, and intrauterine exposure. Air pollution, tobacco smoking, and occupational exposure are discussed as primary sources of carbon monoxide exposure. The effects of cigarette smoking on fetal development and health are excluded and examined in a separate bibliography. (Contains a minimum of 172 citations and includes a subject term index and title list.)

  1. Membrane gas separation. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the research and development of gas separation and purification techniques involving the use of plastic and metal membranes. Among the topics included are isotope separation, osmotic techniques, reverse osmosis, and preparation of membranes for specific separation processes. The permeability of polymer membranes is discussed in terms of physical properties as well as molecular structure. The selectivity of polymeric films for a variety of gases is also included. (Contains a minimum of 168 citations and includes a subject term index and title list.)

  2. Water treatment by reverse osmosis. (Latest citations from the U. S. Patent data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations of selected patents concerning water purification systems and components using reverse osmosis technology. Patents include purification systems and devices for seawater, waste water, and drinking water. Topics also include complete purification systems, valves and distribution components, membranes, supports, storage units, and monitors. Water purification systems using activated charcoal are referenced in a related bibliography. (Contains a minimum of 135 citations and includes a subject term index and title list.)

  3. Lip seals: Lubrication and wear resistance. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the design, development, friction wear, and lubrication of lip seals. Lubrication film thickness, friction forces, cylinder scoring, seal leakage theory, elastohydrodynamic lubrication of metal lip seals, standards and specifications, and lip seal failures and strengths are considered. Geothermal, dredge pump, and rotary shaft applications are discussed. (Contains 250 citations and includes a subject term index and title list.)

  4. Biodegradation of pesticides. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the biological degradation of pesticides. Pesticides such as malathion, parathion and DDT, organophosphates and carbamates, herbicides, fungicides, and rodenticides are examined. Coverage includes the isolation of enzymes specifically able to degrade pesticides, field studies of natural degradation and migration of pesticides, and test tube examination of microbial organisms with the ability to digest pesticides. Degradation products, effects of available nutrients on microbial degradation, and pesticide resistance in natural ecosystems are also discussed. (Contains a minimum of 190 citations and includes a subject term index and title list.)

  5. Bioreactors and fermentation. (Latest citations from the Life Sciences Collection datab base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the use of bioreactors in fermentation processes. Topics include aerobic and anaerobic technologies involving yeasts, microorganisms, and enzymes. These technologies are useful in the production of ethanol, methanol (methane), butanol, organic acids, protein enhancers, and nitrogen enhancers in the dairy, agricultural, food, beverage processing, and medical industries. (Contains a minimum of 230 citations and includes a subject term index and title list.)

  6. Biomedical radiography: radiation protection and safety. (latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the safety of biomedical radiography. Radiation protection methods and techniques are described for both patients and operators. Safety techniques for dental radiology, routine x-rays, radiotherapy, thoracic radiography and other radiology procedures are included. Radiation exposure limits for patients and healthcare workers are defined. (Contains a minimum of 247 citations and includes a subject term index and title list.)

  7. Pumped storage for hydroelectric power. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the design, development, construction, and characteristics of surface and underground pumped storage for hydroelectric power. Pumped storage projects and facilities worldwide are referenced. There is some consideration of research and experimental results of pumped storage studies, as well as modeling. (Contains a minimum of 192 citations and includes a subject term index and title list.)

  8. Air-pollution effects on plants. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the effects of combustion products, and industrial and automotive emissions on vegetation, forest stands, and agricultural crops. References review the use of computer simulations to predict air pollution and examine the effects of acid precipitation and deposition. (Contains 250 citations and includes a subject term index and title list.)

  9. Acid mine drainage. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the control and treatment of acid mine drainage. Techniques discussed for treating wastes containing heavy metals include precipitation, cementation, ion exchange, charge membrane, ultrafiltration, ozonation, solvent extraction, and electrodialysis. The environmental impacts of acid mine drainage on rivers, streams, and lakes are also discussed. (Contains 250 citations and includes a subject term index and title list.)

  10. Cadmium exposure: Toxicity in humans. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-07-01

    The bibliography contains citations concerning the effects of cadmium on humans. Biological monitoring of workers exposed to cadmium is discussed in depth. The effects of cadmium on visual-motor performance, community health, and child and infant development are presented. The citations discuss cadmium as a contributing factor in infertility and renal, kidney, and liver diseases. The effects of smoking on cadmium retention are mentioned. (Contains 250 citations and includes a subject term index and title list.)

  11. Lead: Occupational health hazards. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the health hazards of working with lead-containing material and processes. Health hazards from lead exposure in industrial settings such as resource recovery plants, iron foundries, lead ore processing plants, mines, scrap metal processing plants and yards, tanning facilities, and printing facilities are evaluated. Clinical studies of worker exposure to lead are presented. Occupational Safety and Health Administration (OSHA) lead standards are discussed with regard to abatement procedures for lead exposure in the workplace. (Contains 250 citations and includes a subject term index and title list.)

  12. Chromium toxicity. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning the biological effects of chromium exposure. Topics include the effects on protein metabolism and kidney and liver functions, chromium antigenicity, and the role of chromium as a carcinogenic agent. Sources of chromium contamination are discussed, including occupational exposure and pollution. Methods of analysis are also described. (Contains 250 citations and includes a subject term index and title list.)

  13. Oil pollution sampling, detection, and analysis. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the monitoring and analysis of pollution resulting from oil production and transport operations. Descriptions and evaluations of monitoring methods and devices, tagging and tracing techniques, and analytical techniques, including spectroscopy and chromatography, are among the topics reviewed. Remote sensing methods and oil-laden sediment sampling and analyses are also considered. The majority of the citations pertain to marine pollution, but some attention is given to terrestrial pollution. Pollution effects on flora and fauna are not included. (Contains a minimum of 115 citations and includes a subject term index and title list.)

  14. Cellulose and lignin: biodegradation. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning the biodegradation of materials containing cellulose and lignin. Natural wood decay and sludge digestion are considered. The citations examine chemical and physical mechanisms of degradation, and research on microorganisms involved, for a variety of cellulose and lignin containing materials including straw, municipal wastes, living trees, paper, lumber, and grasses. Genetic engineering studies regarding the isolation, preparation, and characterization of suitable microorganisms for cellulose and lignin degradation are included. (Contains a minimum of 155 citations and includes a subject term index and title list.)

  15. Energy supply and demand modeling. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning the use of mathematical models in trend analysis and forecasting of energy supply and demand factors. Models are presented for the industrial, transportation, and residential sectors. Aspects of long term energy strategies and markets are discussed at the global, national, state, and regional levels. Energy demand and pricing, and econometrics of energy, are explored for electric utilities and natural resources, such as coal, oil, and natural gas. Energy resources are modeled both for fuel usage and for reserves. (Contains 250 citations and includes a subject term index and title list.)

  16. Sea water corrosion. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the corrosion of ships, offshore platforms, steel pilings, cables, and marine equipment. The materials studied include ferrous and nonferrous metals, concrete, and composites. Considerable attention is given to materials selection and testing for the Ocean Thermal Energy Conversion (OTEC) projects. References to corrosion inhibitors are included. (Contains 250 citations and includes a subject term index and title list.)

  17. Bioreactors and cell culturing. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the use of bioreactors and cell cultures to produce monoclonal antibodies, stock cultures, antibiotics, vaccines, proteins, and other chemicals for the pharmaceutical, biomedical, food, and chemical industries. Topics include the application of bioengineering technologies in the design, construction, and control of various types of bioreactors. The use of biochemical mediators in conjunction with these reactors is also reviewed. (Contains 250 citations and includes a subject term index and title list.)

  18. Bioreactors: Waste-water treatment. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the use of bioreactors for wastewater treatment. References are made to stirred tank, photobio, hollow, nonfluidized bed, biofilm, oxidizing, composting, fluidized bed, porous membrane, and plate column reactors employing chemical, microbiological, and physical technologies. Applications in municipal treatment, food processing, chemical, agricultural, mining, and oil refining industries are reviewed. (Contains a minimum of 167 citations and includes a subject term index and title list.)

  19. Composite tribological materials. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning the properties, behavior, and uses of composite tribological materials in and on various objects, devices, and equipment. The citations examine friction and wear characteristics, mechanisms, and the performance of these materials and the objects to which they are applied. Composite tribological materials are used, for example, in bearings, gears, and piston rings. Included are self lubricating materials. (Contains 250 citations and includes a subject term index and title list.)

  20. Asbestos in drinking water. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the occurrence and problems associated with drinking water contaminated by asbestos fibers. Water supply contamination by asbestos cement pipes and factors involved in the release of asbestos fibers are discussed. Topics also include distribution data, epidemiology studies, health effects, detection, and measurement methods. (Contains a minimum of 114 citations and includes a subject term index and title list.)

  1. Asbestos exposure: Health effects. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the health effects of exposure to asbestos in the workplace, at home, and in public sites. Exposure, during procurement of asbestos, removal of asbestos materials, manufacture of materials, and while living and working with materials containing asbestos, is considered. Mortality patterns and clinical studies of exposure, risk, and resulting diseases are presented as well as analytical techniques used to study asbestos health effects. Asbestos removal and abatement questions, and equipment used in these operations are included. (Contains 250 citations and includes a subject term index and title list.)

  2. Laser cooling and trapping of atomic particles. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning theory and experiments on laser cooling and laser trapping of neutral atoms and atomic ions. Atoms and ions are cooled by laser radiation pressure to very low Kelvin temperatures and confined in electromagnetic traps of very high density. Atomic particles discussed include sodium atoms, mercury ions, beryllium ions, magnesium ions, and hydrogen. Applications for high performance spectroscopy, atomic clocks, microwave and optical frequency standards, relativistic neutral particle beam weapons, exotic fuels, cooling of electron beams, and space propulsion are examined. (Contains a minimum of 151 citations and includes a subject term index and title list.)

  3. Asbestos exposure: Legislation, liability, and litigation. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning asbestos exposure resulting in legislation and lawsuits. Personal and corporate litigation cases are cited. Economic problems arising from lawsuits are presented. Monitoring for the determination of standards for legislation is also covered. Recent changes in Occupational Safety and Health Administration (OSHA) and Environmental Protection Agency (EPA) rules and regulations are included. (Contains 250 citations and includes a subject term index and title list.)

  4. Hydrogen production. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the manufacture of hydrogen by electrolysis, photosynthesis, and coal conversion processes. Topics include plant and process evaluations, theoretical aspects and laboratory investigations, and economic analyses. The use of thermonuclear reactors as a process energy source is also discussed. (Contains 250 citations and includes a subject term index and title list.)

  5. Oil spills: Biological effects. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the biological and ecological effects of oil spills. The effects on microorganisms, plants, and animals are studied. Damage assessment, ecological modeling, and environmental impact statements are included. (Contains 250 citations and includes a subject term index and title list.)

  6. Artificial recharge of aquifers. (Latest citations from the selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the use of artificial recharge methods to improve the availability and quality of aquifers. Topics include site studies and evaluation, the use of impounded fresh water and treated wastewater in recharge applications, the role of artificial recharge techniques in groundwater resource management, individual state programs, contaminant behavior, and the engineering aspects of the use of spreading ponds and injection wells. Legal and environmental considerations, as well as the use of computer simulations, are also treated. (Contains 250 citations and includes a subject term index and title list.)

  7. Ceramic heaters. (Latest citations from the U. S. Patent data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations of selected patents concerning ceramic heaters and their applications. Topics include compositions and fabrication methods for ceramic composites having properties of high temperature oxidation and corrosion resistance, thermal shock resistance, and high mechanical strength at high temperatures. Industrial applications of heater systems include use in diesel engine glow plugs, diesel fuel filters, fuel evaporation emission control, exhaust gas cleaning, vehicular air heating, gas sensing, oxygen sensors, gas lasers, and diamond synthesis. (Contains a minimum of 92 citations and includes a subject term index and title list.)

  8. Hydrodynamic journal bearings: Capacity, wear, and lubrication. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning the characteristics of hydrodynamic journal bearings. Bearing load, lubrication, thermal effects, tolerance to misalignment, cavitation, and design are discussed. Studies on the effect of temperature and heat transfer on hydrodynamic films are presented. The impact of surface roughness on hydrodynamic journal bearing performance is also examined. (Contains 250 citations and includes a subject term index and title list.)

  9. Graphite in lubrication. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning graphite and graphite fluoride as solid lubricants for applications requiring dry lubricants or in conjunction with oils or greases to improve lubrication. Fiber graphite is discussed in the manufacture of composite materials with self-lubricating properties. Graphite as a filler in various bearing materials is also considered. (Contains a minimum of 113 citations and includes a subject term index and title list.)

  10. Aquaculture: Algae. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the commercial cultivation of algae as a facet of aquaculture. Topics include descriptions and characteristics of algal species, environmental variables affecting productivity, nutritional aspects, infestation and disease, genetic manipulation, and production technology. End product applications examine algae as biomass for energy production, food source for humans, animal feed source, and a source for chemical by-products such as chlorophylls. Harvesting of algae as a source of single-celled protein is referenced in a related bibliography. (Contains a minimum of 171 citations and includes a subject term index and title list.)

  11. Technology transfer in agriculture. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning technology transfer in agriculture. Topics include applications of technology transfer in aquaculture, forestry, soil maintenance, agricultural pollution, agricultural biotechnology, and control of disease and insect pests. Use of computer technology in agriculture and technology transfers to developing countries are discussed. (Contains a minimum of 178 citations and includes a subject term index and title list.)

  12. Filtration and flocculation in industrial processes. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning theoretical aspects, system design, evaluations, and standards for filtration and flocculation techniques and equipment used in various industrial processes. Applications include air filtration, dust collection, water filtration, dewatering, and flocculant separation. A variety of filter types and flocculation mechanisms is discussed. (Contains 250 citations and includes a subject term index and title list.)

  13. Volcanic eruptions: atmospheric effects. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning gaseous and particulate contributions to the Earth's atmosphere from volcanoes, and the effects these substances have on the climate and the environment. Case studies of specific volcanic eruptions; detection and measurement of volcanic gases, aerosols, and particulates in the atmosphere; environmental effects on the biota; long and short term climatological effects; paleoclimatology and volcanoes; atmospheric and transport modelling; and solar radiation inhibition are among the topics discussed. (Contains a minimum of 179 citations and includes a subject term index and title list.)

  14. Heat pipes. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-10-01

    The bibliography contains citations concerning the theory, design, fabrication, testing, and operation of heat pipes. Applications include heat rejection devices in spacecraft, use in passive solar heating systems and warm air furnaces, and electronic circuit cooling. Heat recovery operations, and materials considerations are also discussed. (Contains 250 citations and includes a subject term index and title list.)

  15. Inland wetlands legislation and management. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning Federal and state laws and management programs for the protection and use of inland wetlands. Utilization of wetlands to control highway runoff and community wastewater is discussed. Wetlands protection programs, restoration projects, resource planning, and wetlands identification methods are cited. References to coastal and salt water wetlands are not included in this bibliography. (Contains 250 citations and includes a subject term index and title list.)

  16. Thermal insulation for residential homes. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning materials and methods used for thermal insulation of residential buildings. The thermal efficiency of window glass, cellular materials, glass wool, fibers, wood, foams, and other insulating materials is reviewed. Construction methods and insulation R values are compared between geographic regions. (Contains a minimum of 217 citations and includes a subject term index and title list.)

  17. Strategic defense and arms control. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-03-01

    The bibliography contains citations concerning studies of relationships between national defense needs and arms control policies. Included are references to specific weapons systems such as the cruise missile, MX missile, Trident submarine, non-nuclear strategic weapons, and chemical weapons. Topics also review strategies involving space, NATO, and the Strategic Defense Initiative. Policies, positions, and negotiations refer to the Strategic Arms Limitation Talks (SALT), the Strategic Arms Reduction Talks (START), the Anti-ballistic Missile Treaty, and international meetings on proliferation of weapons and on the use of space for military missions. (Contains a minimum of 163 citations and includes a subject term index and title list.)

  18. Oil-spill removal techniques and equipment. (Latest citations from Fluidex data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning equipment and techniques for the control, dispersal, cleanup, and disposal of oil spills. Topics include chemical dispersants, booms, and mechanical skimmers. The citations emphasize spill removal for harbors, estuaries, and shorelines, and examine spill impact on water birds and marine life. (Contains a minimum of 180 citations and includes a subject term index and title list.)

  19. Quantum Private Comparison Based on Quantum Search Algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Wei-Wei; Li, Dan; Song, Ting-Ting; Li, Yan-Bing

    2013-05-01

    We propose two quantum private comparison protocols based on quantum search algorithm with the help of a semi-honest third party. Our protocols utilize the properties of quantum search algorithm, the unitary operations, and the single-particle measurements. The security of our protocols is discussed with respect to both the outsider attack and the participant attack. There is no information leaked about the private information and the comparison result, even the third party cannot know these information.

  20. In Search of an Alternative Power Base.

    ERIC Educational Resources Information Center

    Elliott, John

    1981-01-01

    Argues that naturalistic researchers in education who wish to effect change must switch their power base from the bureaucratized educational administration to special interest and pressure groups at the grass roots level. (APM)

  1. In Search of an Alternative Power Base.

    ERIC Educational Resources Information Center

    Elliott, John

    1981-01-01

    Argues that naturalistic researchers in education who wish to effect change must switch their power base from the bureaucratized educational administration to special interest and pressure groups at the grass roots level. (APM)

  2. Categorization of drugs implicated in causing liver injury: Critical assessment based on published case reports.

    PubMed

    Björnsson, Einar S; Hoofnagle, Jay H

    2016-02-01

    An important element in assessing causality in drug-induced liver injury is whether the implicated agent is known to cause hepatotoxicity. We classified drugs into categories based on the number of published reports of convincingly documented, clinically apparent, idiosyncratic liver injury. Drugs described in the website LiverTox (http://livertox.nih.gov) were classified into five categories based on the number of published cases (category A, ≥50; category B, 12-49; category C, 4-11; category D, 1-3; category E, none). Case reports in categories C and D were individually reanalyzed using the Roussel Uclaf Causality Assessment Method. Drugs with fatal cases or with rechallenge were noted. Among 671 individual drugs or closely related agents, 353 (53%) were considered convincingly linked to liver injury in published case reports; 48 (13%) were assigned to category A, 76 (22%) were assigned to category B, 96 (27%) were assigned to category C, and 126 (36%) were assigned to category D. Another 7 (2%) were direct hepatotoxins but only in high doses and placed in a separate category (T). The remaining 318 (47%) drugs had no convincing case report of hepatoxicity in the literature (category E). All except one in category A have been available since 1999, 98% had at least one fatal case and 89% a positive rechallenge. In category B, 54% had a fatal case and 41% a rechallenge. Drugs in categories C and D less frequently had instances of fatal (23% and 7%) or rechallenge cases (26% and 11%). Documentation of hepatoxicity in the medical literature is variable, and many published instances do not stand up to critical review. A standardized system for categorizing drugs for hepatotoxicity potential will help develop objective and reliable, computer-based instruments for assessing causality in drug-induced liver injury. © 2015 by the American Association for the Study of Liver Diseases.

  3. Applying methodological search filters to CAB abstracts to identify research for evidence-based veterinary medicine.

    PubMed

    Murphy, Sarah Anne

    2002-10-01

    The study sought to determine whether methodological search strategies identified by Haynes et al. as most effective for locating information for evidence-based medicine in MEDLINE would be effective in locating information in CAB Abstracts for evidence-based veterinary medicine. Articles published in the year 2000 volumes of the Journal of the American Veterinary Medical Association and Veterinary Record were manually examined and classified by format (original study, review, general article, conference report, decision analysis, case report) and purpose category (etiology, prognosis, diagnosis, and treatment or prevention). Search strategies identified by Haynes et al. were then modified and run on the CAB Abstracts database. Sensitivity and specificity were determined by comparing results to the manual review of the literature. The author manually reviewed 390 articles, 289 articles of which were identified as original studies. Overall, the sensitivity and specificity of the search strategies were disappointing. The methodological search strategies developed by Haynes et al. for MEDLINE were not effective in locating literature for evidence-based veterinary practice in CAB Abstracts. A study examining methodological search strategies for identifying research for evidence-based veterinary practice in the CAB Abstracts database is necessary.

  4. R2 Indicator-Based Multiobjective Search.

    PubMed

    Brockhoff, Dimo; Wagner, Tobias; Trautmann, Heike

    2015-01-01

    In multiobjective optimization, set-based performance indicators are commonly used to assess the quality of a Pareto front approximation. Based on the scalarization obtained by these indicators, a performance comparison of multiobjective optimization algorithms becomes possible. The R2 and the hypervolume (HV) indicator represent two recommended approaches which have shown a correlated behavior in recent empirical studies. Whereas the HV indicator has been comprehensively analyzed in the last years, almost no studies on the R2 indicator exist. In this extended version of our previous conference paper, we thus perform a comprehensive investigation of the properties of the R2 indicator in a theoretical and empirical way. The influence of the number and distribution of the weight vectors on the optimal distribution of μ solutions is analyzed. Based on a comparative analysis, specific characteristics and differences of the R2 and HV indicator are presented. Furthermore, the R2 indicator is integrated into an indicator-based steady-state evolutionary multiobjective optimization algorithm (EMOA). It is shown that the so-called R2-EMOA can accurately approximate the optimal distribution of μ solutions regarding R2.

  5. Enabling Large-Scale IoT-Based Services through Elastic Publish/Subscribe.

    PubMed

    Vavassori, Sergio; Soriano, Javier; Fernández, Rafael

    2017-09-19

    In this paper, we report an algorithm that is designed to leverage the cloud as infrastructure to support Internet of Things (IoT) by elastically scaling in/out so that IoT-based service users never stop receiving sensors' data. This algorithm is able to provide an uninterrupted service to end users even during the scaling operation since its internal state repartitioning is transparent for publishers or subscribers; its scaling operation is time-bounded and depends only on the dimension of the state partitions to be transmitted to the different nodes. We describe its implementation in E-SilboPS, an elastic content-based publish/subscribe (CBPS) system specifically designed to support context-aware sensing and communication in IoT-based services. E-SilboPS is a key internal asset of the FIWARE IoT services enablement platform, which offers an architecture of components specifically designed to capture data from, or act upon, IoT devices as easily as reading/changing the value of attributes linked to context entities. In addition, we discuss the quantitative measurements used to evaluate the scale-out process, as well as the results of this evaluation. This new feature rounds out the context-aware content-based features of E-SilboPS by providing, for example, the necessary middleware for constructing dashboards and monitoring panels that are capable of dynamically changing queries and continuously handling data in IoT-based services.

  6. Entropy-Based Search Algorithm for Experimental Design

    NASA Astrophysics Data System (ADS)

    Malakar, N. K.; Knuth, K. H.

    2011-03-01

    The scientific method relies on the iterated processes of inference and inquiry. The inference phase consists of selecting the most probable models based on the available data; whereas the inquiry phase consists of using what is known about the models to select the most relevant experiment. Optimizing inquiry involves searching the parameterized space of experiments to select the experiment that promises, on average, to be maximally informative. In the case where it is important to learn about each of the model parameters, the relevance of an experiment is quantified by Shannon entropy of the distribution of experimental outcomes predicted by a probable set of models. If the set of potential experiments is described by many parameters, we must search this high-dimensional entropy space. Brute force search methods will be slow and computationally expensive. We present an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment for efficient experimental design. This algorithm is inspired by Skilling's nested sampling algorithm used in inference and borrows the concept of a rising threshold while a set of experiment samples are maintained. We demonstrate that this algorithm not only selects highly relevant experiments, but also is more efficient than brute force search. Such entropic search techniques promise to greatly benefit autonomous experimental design.

  7. Analysis of Product Distribution Strategy in Digital Publishing Industry Based on Game-Theory

    NASA Astrophysics Data System (ADS)

    Xu, Li-ping; Chen, Haiyan

    2017-04-01

    The digital publishing output increased significantly year by year. It has been the most vigorous point of economic growth and has been more important to press and publication industry. Its distribution channel has been diversified, which is different from the traditional industry. A deep research has been done in digital publishing industry, for making clear of the constitution of the industry chain and establishing the model of industry chain. The cooperative and competitive relationship between different distribution channels have been analyzed basing on a game-theory. By comparing the distribution quantity and the market size between the static distribution strategy and dynamic distribution strategy, we get the theory evidence about how to choose the distribution strategy to get the optimal benefit.

  8. Architectural Analysis of Systems Based on the Publisher-Subscriber Style

    NASA Technical Reports Server (NTRS)

    Ganesun, Dharmalingam; Lindvall, Mikael; Ruley, Lamont; Wiegand, Robert; Ly, Vuong; Tsui, Tina

    2010-01-01

    Architectural styles impose constraints on both the topology and the interaction behavior of involved parties. In this paper, we propose an approach for analyzing implemented systems based on the publisher-subscriber architectural style. From the style definition, we derive a set of reusable questions and show that some of them can be answered statically whereas others are best answered using dynamic analysis. The paper explains how the results of static analysis can be used to orchestrate dynamic analysis. The proposed method was successfully applied on the NASA's Goddard Mission Services Evolution Center (GMSEC) software product line. The results show that the GMSEC has a) a novel reusable vendor-independent middleware abstraction layer that allows the NASA's missions to configure the middleware of interest without changing the publishers' or subscribers' source code, and b) some high priority bugs due to behavioral discrepancies, which were eluded during testing and code reviews, among different implementations of the same APIs for different vendors.

  9. A Systematic Review of Outcomes Following Immediate Molar Implant Placement Based on Recently Published Studies.

    PubMed

    Ketabi, Mohammad; Deporter, Douglas; Atenafu, Eshetu G

    2016-12-01

    Immediate implant placement in molar extraction sites has become a treatment option for experienced clinicians. The aim of this study was to provide a systematic review and meta-analysis of outcomes from recent clinical studies with immediate molar implants. A systematic review was undertaken of relevant literature published from November 2008 to May 2015. Data collected included implant survival rates after at least 1 year in function, cumulative crestal bone loss, and implant location (maxilla vs mandible) and diameter. Implant diameters were grouped as "wide" (4-6 mm) or "ultra-wide" (>6-9 mm). Survival and bone loss with 95% CIs were calculated using a random effects model. Meta-analysis techniques were used to compare survival rates and cumulative mean bone loss between immediate and delayed placement implants. Survival rates also were computed and compared between wide and ultra-wide implants using chi-square testing. The quality of each study was assessed using established criteria. The literature search provided 15 papers published between November 2008 and May 2015 that satisfied the inclusion criteria. Data on survival were found for a total of 768 immediate molar implants inserted in 757 patients. Meta-analysis of these data showed an implant survival rate of 98% with no difference between maxilla and mandible. Five studies included delayed molar implants as controls, and no significant differences were detected. A significant difference (p = .048) was found in relation to implant diameter with implant failures being higher (3.67 vs 1.45%) for ultra-wide (>6-9 mm) versus wide (4-6 mm) implants. The majority of the 15 studies were determined to be either "average" (prospective case series) or "fair" (retrospective) in quality. While there are still no published reports from double-blind, randomized, controlled (best quality) clinical trials of immediate molar implant placement, high survival rates have been reported. The present data, however

  10. Multiparty Quantum Key Agreement Based on Quantum Search Algorithm

    NASA Astrophysics Data System (ADS)

    Cao, Hao; Ma, Wenping

    2017-03-01

    Quantum key agreement is an important topic that the shared key must be negotiated equally by all participants, and any nontrivial subset of participants cannot fully determine the shared key. To date, the embed modes of subkey in all the previously proposed quantum key agreement protocols are based on either BB84 or entangled states. The research of the quantum key agreement protocol based on quantum search algorithms is still blank. In this paper, on the basis of investigating the properties of quantum search algorithms, we propose the first quantum key agreement protocol whose embed mode of subkey is based on a quantum search algorithm known as Grover’s algorithm. A novel example of protocols with 5 – party is presented. The efficiency analysis shows that our protocol is prior to existing MQKA protocols. Furthermore it is secure against both external attack and internal attacks.

  11. Multiparty Quantum Key Agreement Based on Quantum Search Algorithm

    PubMed Central

    Cao, Hao; Ma, Wenping

    2017-01-01

    Quantum key agreement is an important topic that the shared key must be negotiated equally by all participants, and any nontrivial subset of participants cannot fully determine the shared key. To date, the embed modes of subkey in all the previously proposed quantum key agreement protocols are based on either BB84 or entangled states. The research of the quantum key agreement protocol based on quantum search algorithms is still blank. In this paper, on the basis of investigating the properties of quantum search algorithms, we propose the first quantum key agreement protocol whose embed mode of subkey is based on a quantum search algorithm known as Grover’s algorithm. A novel example of protocols with 5 – party is presented. The efficiency analysis shows that our protocol is prior to existing MQKA protocols. Furthermore it is secure against both external attack and internal attacks. PMID:28332610

  12. Multiparty Quantum Key Agreement Based on Quantum Search Algorithm.

    PubMed

    Cao, Hao; Ma, Wenping

    2017-03-23

    Quantum key agreement is an important topic that the shared key must be negotiated equally by all participants, and any nontrivial subset of participants cannot fully determine the shared key. To date, the embed modes of subkey in all the previously proposed quantum key agreement protocols are based on either BB84 or entangled states. The research of the quantum key agreement protocol based on quantum search algorithms is still blank. In this paper, on the basis of investigating the properties of quantum search algorithms, we propose the first quantum key agreement protocol whose embed mode of subkey is based on a quantum search algorithm known as Grover's algorithm. A novel example of protocols with 5 - party is presented. The efficiency analysis shows that our protocol is prior to existing MQKA protocols. Furthermore it is secure against both external attack and internal attacks.

  13. Evidence-based medicine training in undergraduate medical education: a review and critique of the literature published 2006-2011.

    PubMed

    Maggio, Lauren A; Tannery, Nancy H; Chen, H Carrie; ten Cate, Olle; O'Brien, Bridget

    2013-07-01

    To characterize recent evidence-based medicine (EBM) educational interventions for medical students and suggest future directions for EBM education. The authors searched the MEDLINE, Scopus, Educational Resource Information Center, and Evidence-Based Medicine Reviews databases for English-language articles published between 2006 and 2011 that featured medical students and interventions addressing multiple EBM skills. They extracted data on learner and instructor characteristics, educational settings, teaching methods, and EBM skills covered. The 20 included articles described interventions delivered in 12 countries in classroom (75%), clinic (25%), and/or online (20%) environments. The majority (60%) focused on clinical students, whereas 30% targeted preclinical students and 10% included both. EBM skills addressed included recognizing a knowledge gap (20%), asking a clinical question (90%), searching for information (90%), appraising information (85%), applying information (65%), and evaluating practice change (5%). Physicians were most often identified as instructors (60%); co-teachers included librarians (20%), allied health professionals (10%), and faculty from other disciplines (10%). Many studies (60%) included interventions at multiple points during one year, but none were longitudinal across students' tenures. Teaching methods varied. Intervention efficacy could not be determined. Settings, learner levels and instructors, teaching methods, and covered skills differed across interventions. Authors writing about EBM interventions should include detailed descriptions and employ more rigorous research methods to allow others to draw conclusions about efficacy. When designing EBM interventions, educators should consider trends in medical education (e.g., online learning, interprofessional education) and in health care (e.g., patient-centered care, electronic health records).

  14. Pharmacophore alignment search tool: influence of scoring systems on text-based similarity searching.

    PubMed

    Hähnke, Volker; Schneider, Gisbert

    2011-06-01

    The text-based similarity searching method Pharmacophore Alignment Search Tool is grounded on pairwise comparisons of potential pharmacophoric points between a query and screening compounds. The underlying scoring matrix is of critical importance for successful virtual screening and hit retrieval from large compound libraries. Here, we compare three conceptually different computational methods for systematic deduction of scoring matrices: assignment-based, alignment-based, and stochastic optimization. All three methods resulted in optimized pharmacophore scoring matrices with significantly superior retrospective performance in comparison with simplistic scoring schemes. Computer-generated similarity matrices of pharmacophoric features turned out to agree well with a manually constructed matrix. We introduce the concept of position-specific scoring to text-based similarity searching so that knowledge about specific ligand-receptor binding patterns can be included and demonstrate its benefit for hit retrieval. The approach was also used for automated pharmacophore elucidation in agonists of peroxisome proliferator activated receptor gamma, successfully identifying key interactions for receptor activation.

  15. Publishing scientific papers based on Master's and Ph.D. theses from a small scientific community: case study of Croatian medical schools.

    PubMed

    Frković, Vedran; Skender, Tomislav; Dojćinović, Bojan; Bilić-Zulle, Lidija

    2003-02-01

    To evaluate publishing activity of medical doctors after they have obtained Master's or Ph.D. degree at the Rijeka and Zagreb University Schools of Medicine in Croatia, and establish the number of journal articles based on these theses. Data on Master's and Ph.D. theses defended at the Rijeka and Zagreb University Schools of Medicine in the 1990-1999 period were collected by hand-search of the archive. MEDLINE and Current Contents databases were searched for journal articles resulting from the theses. During the 10-year period, 1,535 Master's and 634 Ph.D. theses were defended at the Rijeka and Zagreb University Schools of Medicine (253 Master's and 138 Ph.D. theses from Rijeka and 1,282 Master's and 496 Ph.D. theses from Zagreb). There were 201 (14%) Master's and 218 (34%) Ph.D. theses that resulted in articles published in journals indexed in MEDLINE (13% of Master's and 11% of Ph.D. theses from Rijeka, and 14% of Master's and 41% of Ph.D. theses from Zagreb). Also, 97 (6%) Master's and 129 (20%) Ph.D. theses that resulted in articles published in Current Contents journals (8% of Master's and 6% of Ph.D. theses from Rijeka, and 6% of Master's and 24% of Ph.D. theses from Zagreb). There was no significant difference between the two Universities with respect to published articles based on Master's theses, but there were significantly more articles from Ph.D. theses in Zagreb (p<0.001). Most of the theses resulted in a single publication (95%), 19 (5%) in 2, and 2 in 3 publications. Out of all 453 journal articles, 31% were published in Croatian and 69% in international journals. Most Croatian Master's and Ph.D. theses are not made available to the scientific community. There should be more institutional effort directed at the stimulation of postgraduate students to publish their scientific work.

  16. Optimal fractional order PID design via Tabu Search based algorithm.

    PubMed

    Ateş, Abdullah; Yeroglu, Celaleddin

    2016-01-01

    This paper presents an optimization method based on the Tabu Search Algorithm (TSA) to design a Fractional-Order Proportional-Integral-Derivative (FOPID) controller. All parameter computations of the FOPID employ random initial conditions, using the proposed optimization method. Illustrative examples demonstrate the performance of the proposed FOPID controller design method.

  17. Health Effects Profiles for Searching Selected Lockheed DIALOG Data Bases.

    ERIC Educational Resources Information Center

    Clement, Linda Lee

    This preliminary study attempted to determine the most effective search strategies for the topic "health effects" in relation to specific chemicals and/or pollutants--in this case, asbestos--for each of five selected Lockheed DIALOG data bases: BIOSIS Previews, Chemical Abstracts Condensates (Chemcon), NTIS, Enviroline, and Pollution…

  18. Computer-Assisted Search Of Large Textual Data Bases

    NASA Technical Reports Server (NTRS)

    Driscoll, James R.

    1995-01-01

    "QA" denotes high-speed computer system for searching diverse collections of documents including (but not limited to) technical reference manuals, legal documents, medical documents, news releases, and patents. Incorporates previously available and emerging information-retrieval technology to help user intelligently and rapidly locate information found in large textual data bases. Technology includes provision for inquiries in natural language; statistical ranking of retrieved information; artificial-intelligence implementation of semantics, in which "surface level" knowledge found in text used to improve ranking of retrieved information; and relevance feedback, in which user's judgements of relevance of some retrieved documents used automatically to modify search for further information.

  19. Searching for adaptive traits in genetic resources - phenology based approach

    NASA Astrophysics Data System (ADS)

    Bari, Abdallah

    2015-04-01

    Searching for adaptive traits in genetic resources - phenology based approach Abdallah Bari, Kenneth Street, Eddy De Pauw, Jalal Eddin Omari, and Chandra M. Biradar International Center for Agricultural Research in the Dry Areas, Rabat Institutes, Rabat, Morocco Phenology is an important plant trait not only for assessing and forecasting food production but also for searching in genebanks for adaptive traits. Among the phenological parameters we have been considering to search for such adaptive and rare traits are the onset (sowing period) and the seasonality (growing period). Currently an application is being developed as part of the focused identification of germplasm strategy (FIGS) approach to use climatic data in order to identify crop growing seasons and characterize them in terms of onset and duration. These approximations of growing period characteristics can then be used to estimate flowering and maturity dates for dryland crops, such as wheat, barley, faba bean, lentils and chickpea, and assess, among others, phenology-related traits such as days to heading [dhe] and grain filling period [gfp]. The approach followed here is based on first calculating long term average daily temperatures by fitting a curve to the monthly data over days from beginning of the year. Prior to the identification of these phenological stages the onset is extracted first from onset integer raster GIS layers developed based on a model of the growing period that considers both moisture and temperature limitations. The paper presents some examples of real applications of the approach to search for rare and adaptive traits.

  20. Supporting inter-topic entity search for biomedical Linked Data based on heterogeneous relationships.

    PubMed

    Zong, Nansu; Lee, Sungin; Ahn, Jinhyun; Kim, Hong-Gee

    2017-08-01

    The keyword-based entity search restricts search space based on the preference of search. When given keywords and preferences are not related to the same biomedical topic, existing biomedical Linked Data search engines fail to deliver satisfactory results. This research aims to tackle this issue by supporting an inter-topic search-improving search with inputs, keywords and preferences, under different topics. This study developed an effective algorithm in which the relations between biomedical entities were used in tandem with a keyword-based entity search, Siren. The algorithm, PERank, which is an adaptation of Personalized PageRank (PPR), uses a pair of input: (1) search preferences, and (2) entities from a keyword-based entity search with a keyword query, to formalize the search results on-the-fly based on the index of the precomputed Individual Personalized PageRank Vectors (IPPVs). Our experiments were performed over ten linked life datasets for two query sets, one with keyword-preference topic correspondence (intra-topic search), and the other without (inter-topic search). The experiments showed that the proposed method achieved better search results, for example a 14% increase in precision for the inter-topic search than the baseline keyword-based search engine. The proposed method improved the keyword-based biomedical entity search by supporting the inter-topic search without affecting the intra-topic search based on the relations between different entities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Music-Based Training for Pediatric CI Recipients: A Systematic Analysis of Published Studies

    PubMed Central

    Gfeller, Kate

    2016-01-01

    In recent years, there has been growing interest in the use of music-based training to enhance speech and language development in children with normal hearing and some forms of communication disorders, including pediatric CI users. The use of music training for CI users may initially seem incongruous given that signal processing for CIs presents a degraded version of pitch and timbre, both key elements in music. Furthermore, empirical data of systematic studies of music training, particularly in relation to transfer to speech skills are limited. This study describes the rationale for music training of CI users, describes key features of published studies of music training with CI users, and highlights some developmental and logistical issues that should be taken into account when interpreting or planning studies of music training and speech outcomes with pediatric CI recipients. PMID:27246744

  2. Maximum common substructure-based data fusion in similarity searching.

    PubMed

    Duesbury, Edmund; Holliday, John; Willett, Peter

    2015-02-23

    Data fusion has been shown to work very well when applied to fingerprint-based similarity searching, yet little is known of its application to maximum common substructure (MCS)-based similarity searching. Two similarity search applications of the MCS will be focused on here. Typically, the number of bonds in the MCS, as well as the bonds in the two molecules being compared, are used in a similarity coefficient. The power of this technique can be extended using data fusion, where the MCS similarities of a set of reference molecules against one database molecule are fused. This "group fusion" technique forms the first application of the MCS in this work. The other application is that of the chemical hyperstructure. The hyperstructure concept is an alternative form of data fusion, being a hypothetical molecule that is constructed from the overlap of a set of existing molecules. This paper compares fingerprint group fusion (extended-connectivity fingerprints), MCS similarity group fusion, and hyperstructure similarity searching, and describes their relative merits and complementarity in virtual screening. It is concluded that the hyperstructure approach as implemented here is less generally effective than conventional fingerprint approaches.

  3. Desktop Publishing.

    ERIC Educational Resources Information Center

    Stanley, Milt

    1986-01-01

    Defines desktop publishing, describes microcomputer developments and software tools that make it possible, and discusses its use as an instructional tool to improve writing skills. Reasons why students' work should be published, examples of what to publish, and types of software and hardware to facilitate publishing are reviewed. (MBR)

  4. Search-based model identification of smart-structure damage

    NASA Technical Reports Server (NTRS)

    Glass, B. J.; Macalou, A.

    1991-01-01

    This paper describes the use of a combined model and parameter identification approach, based on modal analysis and artificial intelligence (AI) techniques, for identifying damage or flaws in a rotating truss structure incorporating embedded piezoceramic sensors. This smart structure example is representative of a class of structures commonly found in aerospace systems and next generation space structures. Artificial intelligence techniques of classification, heuristic search, and an object-oriented knowledge base are used in an AI-based model identification approach. A finite model space is classified into a search tree, over which a variant of best-first search is used to identify the model whose stored response most closely matches that of the input. Newly-encountered models can be incorporated into the model space. This adaptativeness demonstrates the potential for learning control. Following this output-error model identification, numerical parameter identification is used to further refine the identified model. Given the rotating truss example in this paper, noisy data corresponding to various damage configurations are input to both this approach and a conventional parameter identification method. The combination of the AI-based model identification with parameter identification is shown to lead to smaller parameter corrections than required by the use of parameter identification alone.

  5. Exploring FlyBase Data Using QuickSearch.

    PubMed

    Marygold, Steven J; Antonazzo, Giulia; Attrill, Helen; Costa, Marta; Crosby, Madeline A; Dos Santos, Gilberto; Goodman, Joshua L; Gramates, L Sian; Matthews, Beverley B; Rey, Alix J; Thurmond, Jim

    2016-12-08

    FlyBase (flybase.org) is the primary online database of genetic, genomic, and functional information about Drosophila species, with a major focus on the model organism Drosophila melanogaster. The long and rich history of Drosophila research, combined with recent surges in genomic-scale and high-throughput technologies, mean that FlyBase now houses a huge quantity of data. Researchers need to be able to rapidly and intuitively query these data, and the QuickSearch tool has been designed to meet these needs. This tool is conveniently located on the FlyBase homepage and is organized into a series of simple tabbed interfaces that cover the major data and annotation classes within the database. This unit describes the functionality of all aspects of the QuickSearch tool. With this knowledge, FlyBase users will be equipped to take full advantage of all QuickSearch features and thereby gain improved access to data relevant to their research. © 2016 by John Wiley & Sons, Inc.

  6. Developing a distributed HTML5-based search engine for geospatial resource discovery

    NASA Astrophysics Data System (ADS)

    ZHOU, N.; XIA, J.; Nebert, D.; Yang, C.; Gui, Z.; Liu, K.

    2013-12-01

    With explosive growth of data, Geospatial Cyberinfrastructure(GCI) components are developed to manage geospatial resources, such as data discovery and data publishing. However, the efficiency of geospatial resources discovery is still challenging in that: (1) existing GCIs are usually developed for users of specific domains. Users may have to visit a number of GCIs to find appropriate resources; (2) The complexity of decentralized network environment usually results in slow response and pool user experience; (3) Users who use different browsers and devices may have very different user experiences because of the diversity of front-end platforms (e.g. Silverlight, Flash or HTML). To address these issues, we developed a distributed and HTML5-based search engine. Specifically, (1)the search engine adopts a brokering approach to retrieve geospatial metadata from various and distributed GCIs; (2) the asynchronous record retrieval mode enhances the search performance and user interactivity; (3) the search engine based on HTML5 is able to provide unified access capabilities for users with different devices (e.g. tablet and smartphone).

  7. An expert system for performance-based direct delivery of published clinical evidence.

    PubMed

    Balas, E A; Li, Z R; Spencer, D C; Jaffrey, F; Brent, E; Mitchell, J A

    1996-01-01

    To develop a system for clinical performance improvement through rule-based analysis of medical practice patterns and individualized distribution of published scientific evidence. The Quality Feedback Expert System (QFES) was developed by applying a Level-5 expert system shell to generate clinical direct reports for performance improvement. The system comprises three data and knowledge bases: 1) a knowledge base of measurable clinical practice parameters; 2) a practice pattern database of provider-specific numbers of patients and clinical activities; and 3) a management rule base comprising "redline rules" that identify providers whose practice styles vary significantly. Clinical direct reports consist of a table of practice data highlighting individual utilization vs recommendation and selected pertinent statements from medical literature. The QFES supports integration of recommendations from several guidelines into a comprehensive and measurable quality improvement plan, analysis of actual practice patterns and comparison with accepted recommendations, and generation of a confidential individualized direct report to those who significantly deviate from clinical recommendations. The feasibility of the practice pattern analysis by the QFES was demonstrated in a sample of 182 urinary tract infection cases from a primary care clinic. In a set of clinical activities, four questions/procedures were associated with significant (p < 0.001) and unexplained variation. The QFES provides a flexible tool for the implementation of clinical practice guidelines in diverse and changing clinical areas without the need for special program development. Preliminary studies indicate utility in the analysis of clinical practice variation and deviations. Using data obtained through a retrospective chart audit, the QFES was able to detect overutilization, and to identify nonrandom differences in practice patterns.

  8. Two Quantum Direct Communication Protocols Based on Quantum Search Algorithm

    NASA Astrophysics Data System (ADS)

    Xu, Shu-Jiang; Chen, Xiu-Bo; Wang, Lian-Hai; Niu, Xin-Xin; Yang, Yi-Xian

    2015-07-01

    Based on the properties of two-qubit Grover's quantum search algorithm, we propose two quantum direct communication protocols, including a deterministic secure quantum communication and a quantum secure direct communication protocol. Secret messages can be directly sent from the sender to the receiver by using two-qubit unitary operations and the single photon measurement with one of the proposed protocols. Theoretical analysis shows that the security of the proposed protocols can be highly ensured.

  9. 32 CFR 634.52 - Search incident to impoundment based on criminal activity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Search incident to impoundment based on criminal... Privately Owned Vehicles § 634.52 Search incident to impoundment based on criminal activity. Search of a POV... and crime-related impoundments and abandoned vehicle seizures. A property search related to...

  10. 32 CFR 634.52 - Search incident to impoundment based on criminal activity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Search incident to impoundment based on criminal... Privately Owned Vehicles § 634.52 Search incident to impoundment based on criminal activity. Search of a POV... and crime-related impoundments and abandoned vehicle seizures. A property search related to...

  11. 32 CFR 634.52 - Search incident to impoundment based on criminal activity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Search incident to impoundment based on criminal... Privately Owned Vehicles § 634.52 Search incident to impoundment based on criminal activity. Search of a POV... and crime-related impoundments and abandoned vehicle seizures. A property search related to an...

  12. 32 CFR 634.52 - Search incident to impoundment based on criminal activity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Search incident to impoundment based on criminal... Privately Owned Vehicles § 634.52 Search incident to impoundment based on criminal activity. Search of a POV... and crime-related impoundments and abandoned vehicle seizures. A property search related to an...

  13. 32 CFR 634.52 - Search incident to impoundment based on criminal activity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Search incident to impoundment based on criminal... Privately Owned Vehicles § 634.52 Search incident to impoundment based on criminal activity. Search of a POV... and crime-related impoundments and abandoned vehicle seizures. A property search related to an...

  14. Producing an Online Undergraduate Literary Magazine: A Guide to Using Problem-Based Learning in the Writing and Publishing Classroom

    ERIC Educational Resources Information Center

    Persichetti, Amy L.

    2016-01-01

    This article will illustrate how a problem-based learning (PBL) course (Savery, 2006) can be used in a writing program as a vehicle for both creative and preprofessional learning. English 420: Writing, Publishing, and Editing is offered every fall, and its counterpart, English 423: Writing, Publishing, and Editing is offered each spring. The…

  15. Producing an Online Undergraduate Literary Magazine: A Guide to Using Problem-Based Learning in the Writing and Publishing Classroom

    ERIC Educational Resources Information Center

    Persichetti, Amy L.

    2016-01-01

    This article will illustrate how a problem-based learning (PBL) course (Savery, 2006) can be used in a writing program as a vehicle for both creative and preprofessional learning. English 420: Writing, Publishing, and Editing is offered every fall, and its counterpart, English 423: Writing, Publishing, and Editing is offered each spring. The…

  16. StudySearch: a web-based application for posting and searching clinical research studies.

    PubMed

    Gonsenhauser, Blair; Hallarn, Rose; Carpenter, Daniel; Para, Michael F; Reider, Carson R

    2016-03-01

    Participant accrual into research studies is critical to advancing clinical and translational research to clinical care. Without sufficient recruitment, the purpose of any research study cannot be realized; yet, low recruitment and enrollment of participants persist. StudySearch is a web-based application designed to provide an easily readable, publicly accessible, and searchable listing of IRB-approved protocols that are accruing study participants. The Regulatory, Recruitment and Biomedical Informatics Cores of the Center for Clinical and Translational Science (CCTS) at The Ohio State University developed this research study posting platform. Postings include basic descriptive information: study title, purpose of the study, eligibility criteria and study personnel contact information. Language concerning benefits and/or inducements is not included; therefore, while IRB approval for a study to be listed on StudySearch is required, IRB approval of the posted language is not. Studies are listed by one of two methods; one automated and one manual: (1). Studies registered on ClinicalTrials.gov are automatically downloaded once a month; or (2). Studies are submitted directly by researchers to the CCTS Regulatory Core staff. In either case, final language is a result of an iterative process between researchers and CCTS staff. Deployed in January 2011 at OSU, this application has grown to approximately 200 studies currently posted and 1500 unique visitors per month. Locally, StudySearch is part of the CCTS recruitment toolkit. Features continue to be modified to better accommodate user behaviors. Nationally, this open source application is available for use. Copyright © 2016 American Federation for Medical Research.

  17. StudySearch: a web-based application for posting and searching clinical research studies

    PubMed Central

    Gonsenhauser, Blair; Hallarn, Rose; Carpenter, Daniel; Para, Michael F; Reider, Carson R

    2016-01-01

    Participant accrual into research studies is critical to advancing clinical and translational research to clinical care. Without sufficient recruitment, the purpose of any research study cannot be realized; yet, low recruitment and enrollment of participants persist. StudySearch is a web-based application designed to provide an easily readable, publicly accessible, and searchable listing of IRB-approved protocols that are accruing study participants. The Regulatory, Recruitment and Biomedical Informatics Cores of the Center for Clinical and Translational Science (CCTS) at The Ohio State University developed this research study posting platform. Postings include basic descriptive information: study title, purpose of the study, eligibility criteria and study personnel contact information. Language concerning benefits and/or inducements is not included; therefore, while IRB approval for a study to be listed on StudySearch is required, IRB approval of the posted language is not. Studies are listed by one of two methods; one automated and one manual: (1). Studies registered on ClinicalTrials.gov are automatically downloaded once a month; or (2). Studies are submitted directly by researchers to the CCTS Regulatory Core staff. In either case, final language is a result of an iterative process between researchers and CCTS staff. Deployed in January 2011 at OSU, this application has grown to approximately 200 studies currently posted and 1500 unique visitors per month. Locally, StudySearch is part of the CCTS recruitment toolkit. Features continue to be modified to better accommodate user behaviors. Nationally, this open source application is available for use. PMID:26912012

  18. Evidence based medicine--where do articles published in local indexed journals stand?

    PubMed

    Chinoy, Muhammad Amin; Ahmad, Tashfeen; Tayyab, Muhammad; Raza, Soulat

    2009-01-01

    The recent emphasis on using "evidence based medicine" for decision-making in patient care issues has prompted many publishers to mention the level of evidence of articles in their journals. The "quality" of a journal may thus be reflected by the proportion of articles with high levels of evidence, apart from other criteria. We aimed to determine the level of evidence of articles in indexed Pakistani medical journals. Two journals were selected: Journal of Pakistan Medical Association (JPMA) and Journal of College of Physician and Surgeons, Pakistan (JCPSP). Based on the information in the abstracts, all articles from 2003 and 2006 were categorized according to guidelines of Center for Evidence Based Medicine, Oxford, UK. 882 items/articles were reviewed. Of these, 270 (31%) were scientific articles within which 51% belonged to the "Therapeutic" and 25% to the "Prognostic" type. Only 27% had a high level of evidence (1 and 2) while a majority of 55% had level 4 evidence. Although there was a higher proportion of scientific research articles in JCPSP than JPMA (36% vs. 25%). no major difference in the levels of evidence was noted between the two journals, nor between 2003 and 2006. Moreover, the results were quite comparable to similar international studies. The level of evidence in articles in our leading local journals compares favourably with international literature. We recommend that levels of evidence be stated with abstracts in local journals not only to help the clinicians in making decisions on the best available evidence, but also to elevate the "quality" of these journals.

  19. BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results.

    PubMed

    Worley, K C; Wiese, B A; Smith, R F

    1995-09-01

    BEAUTY (BLAST enhanced alignment utility) is an enhanced version of the NCBI's BLAST data base search tool that facilitates identification of the functions of matched sequences. We have created new data bases of conserved regions and functional domains for protein sequences in NCBI's Entrez data base, and BEAUTY allows this information to be incorporated directly into BLAST search results. A Conserved Regions Data Base, containing the locations of conserved regions within Entrez protein sequences, was constructed by (1) clustering the entire data base into families, (2) aligning each family using our PIMA multiple sequence alignment program, and (3) scanning the multiple alignments to locate the conserved regions within each aligned sequence. A separate Annotated Domains Data Base was constructed by extracting the locations of all annotated domains and sites from sequences represented in the Entrez, PROSITE, BLOCKS, and PRINTS data bases. BEAUTY performs a BLAST search of those Entrez sequences with conserved regions and/or annotated domains. BEAUTY then uses the information from the Conserved Regions and Annotated Domains data bases to generate, for each matched sequence, a schematic display that allows one to directly compare the relative locations of (1) the conserved regions, (2) annotated domains and sites, and (3) the locally aligned regions matched in the BLAST search. In addition, BEAUTY search results include World-Wide Web hypertext links to a number of external data bases that provide a variety of additional types of information on the function of matched sequences. This convenient integration of protein families, conserved regions, annotated domains, alignment displays, and World-Wide Web resources greatly enhances the biological informativeness of sequence similarity searches. BEAUTY searches can be performed remotely on our system using the "BCM Search Launcher" World-Wide Web pages (URL is < http:/ /gc.bcm.tmc.edu:8088/ search-launcher/launcher.html > ).

  20. A Computer Based Training Program on Typesetting for Desktop Publishing Professionals.

    ERIC Educational Resources Information Center

    Gelfand, Andrew

    This report describes the development of a project designed to enable new users of desktop publishing technologies to produce typeset documents which approach or match commercial quality standards. "Typesetting--A Tutorial for the Desktop Publisher" is a computer assisted instructional (CAI) program that provides students with an understanding of…

  1. Underwater Sensor Network Redeployment Algorithm Based on Wolf Search

    PubMed Central

    Jiang, Peng; Feng, Yang; Wu, Feng

    2016-01-01

    This study addresses the optimization of node redeployment coverage in underwater wireless sensor networks. Given that nodes could easily become invalid under a poor environment and the large scale of underwater wireless sensor networks, an underwater sensor network redeployment algorithm was developed based on wolf search. This study is to apply the wolf search algorithm combined with crowded degree control in the deployment of underwater wireless sensor networks. The proposed algorithm uses nodes to ensure coverage of the events, and it avoids the prematurity of the nodes. The algorithm has good coverage effects. In addition, considering that obstacles exist in the underwater environment, nodes are prevented from being invalid by imitating the mechanism of avoiding predators. Thus, the energy consumption of the network is reduced. Comparative analysis shows that the algorithm is simple and effective in wireless sensor network deployment. Compared with the optimized artificial fish swarm algorithm, the proposed algorithm exhibits advantages in network coverage, energy conservation, and obstacle avoidance. PMID:27775659

  2. Galileo FOC Satellite Group Delay Estimation based on Raw Method and published IOV Metadata

    NASA Astrophysics Data System (ADS)

    Reckeweg, Florian; Schönemann, Erik; Springer, Tim; Enderle, Werner

    2017-04-01

    In December 2016, the European GNSS Agency (GSA) published the Galileo In-Orbit Validation (IOV) satellite metadata. These metadata include among others the so-called Galileo satellite group delays, which were measured in an absolute sense by the satellite manufacturer on-ground for all three Galileo frequency bands E1, E5 and E6. Therewith Galileo is the first Global Navigation Satellite System (GNSS) for which absolute calibration values for satellite on-board group delays have been published. The different satellite group delays for the three frequency bands lead to the fact that the signals will not be transmitted at exactly the same epoch. Up to now, due to the lack of absolute group delays, it is common practice in GNSS analyses to estimate and apply the differences of these satellite group delays, commonly known as differential code biases (DCBs). However, this has the drawback that the determination of the "raw" clock and the absolute ionosphere is not possible. The use of absolute bias calibrations for satellites and receivers is a major step into the direction of more realistic (in a physical sense) clock and atmosphere estimates. The Navigation Support Office at the European Space Operation Centre (ESOC) was from the beginning involved in the validation process of the Galileo metadata. For the work presented in this presentation we will use the absolute bias calibrations of the Galileo IOV satellites to estimate and validate the absolute receiver group delays of the ESOC GNSS network and vice versa. The receiver group delays have exemplarily been calibrated in a calibration campaign with an IFEN GNSS Signal-Simulator at ESOC. Based on the calibrated network, making use of the ionosphere constraints given by the IOV satellites, GNSS raw observations are processed to estimate satellite group delays for the operational Galileo (Full Operational Capability) FOC satellites. In addition, "raw" satellite clock offsets are estimated, which are free of the

  3. MSTAR's extensible search engine and model-based inferencing toolkit

    NASA Astrophysics Data System (ADS)

    Wissinger, John; Ristroph, Robert; Diemunsch, Joseph R.; Severson, William E.; Fruedenthal, Eric

    1999-08-01

    The DARPA/AFRL 'Moving and Stationary Target Acquisition and Recognition' (MSTAR) program is developing a model-based vision approach to Synthetic Aperture Radar (SAR) Automatic Target Recognition (ATR). The motivation for this work is to develop a high performance ATR capability that can identify ground targets in highly unconstrained imaging scenarios that include variable image acquisition geometry, arbitrary target pose and configuration state, differences in target deployment situation, and strong intra-class variations. The MSTAR approach utilizes radar scattering models in an on-line hypothesize-and-test operation that compares predicted target signature statistics with features extracted from image data in an attempt to determine a 'best fit' explanation of the observed image. Central to this processing paradigm is the Search algorithm, which provides intelligent control in selecting features to measure and hypotheses to test, as well as in making the decision about when to stop processing and report a specific target type or clutter. Intelligent management of computation performed by the Search module is a key enabler to scaling the model-based approach to the large hypothesis spaces typical of realistic ATR problems. In this paper, we describe the present state of design and implementation of the MSTAR Search engine, as it has matured over the last three years of the MSTAR program. The evolution has been driven by a continually expanding problem domain that now includes 30 target types, viewed under arbitrary squint/depression, with articulations, reconfigurations, revetments, variable background, and up to 30% blocking occlusion. We believe that the research directions that have been inspired by MSTAR's challenging problem domain are leading to broadly applicable search methodologies that are relevant to computer vision systems in many areas.

  4. Publisher's Note: Search for ultrahigh energy neutrinos in highly inclined events at the Pierre Auger Observatory [Phys. Rev. D 84, 122005 (2011)

    NASA Astrophysics Data System (ADS)

    Abreu, P.; Aglietta, M.; Ahlers, M.; Ahn, E. J.; Albuquerque, I. F. M.; Allard, D.; Allekotte, I.; Allen, J.; Allison, P.; Almela, A.; Alvarez Castillo, J.; Alvarez-Muñiz, J.; Ambrosio, M.; Aminaei, A.; Anchordoqui, L.; Andringa, S.; Anticic, T.; Aramo, C.; Arganda, E.; Arqueros, F.; Asorey, H.; Assis, P.; Aublin, J.; Ave, M.; Avenier, M.; Avila, G.; Bäcker, T.; Badescu, A. M.; Balzer, M.; Barber, K. B.; Barbosa, A. F.; Bardenet, R.; Barroso, S. L. C.; Baughman, B.; Bäuml, J.; Beatty, J. J.; Becker, B. R.; Becker, K. H.; Bellétoile, A.; Bellido, J. A.; Benzvi, S.; Berat, C.; Bertou, X.; Biermann, P. L.; Billoir, P.; Blanco, F.; Blanco, M.; Bleve, C.; Blümer, H.; Bohácová, M.; Boncioli, D.; Bonifazi, C.; Bonino, R.; Borodai, N.; Brack, J.; Brancus, I.; Brogueira, P.; Brown, W. C.; Bruijn, R.; Buchholz, P.; Bueno, A.; Burton, R. E.; Caballero-Mora, K. S.; Caccianiga, B.; Caramete, L.; Caruso, R.; Castellina, A.; Catalano, O.; Cataldi, G.; Cazon, L.; Cester, R.; Chauvin, J.; Cheng, S. H.; Chiavassa, A.; Chinellato, J. A.; Chirinos Diaz, J.; Chudoba, J.; Clay, R. W.; Coluccia, M. R.; Conceição, R.; Contreras, F.; Cook, H.; Cooper, M. J.; Coppens, J.; Cordier, A.; Coutu, S.; Covault, C. E.; Creusot, A.; Criss, A.; Cronin, J.; Curutiu, A.; Dagoret-Campagne, S.; Dallier, R.; Dasso, S.; Daumiller, K.; Dawson, B. R.; de Almeida, R. M.; de Domenico, M.; de Donato, C.; de Jong, S. J.; de La Vega, G.; de Mello, W. J. M., Jr.; de Mello Neto, J. R. T.; de Mitri, I.; de Souza, V.; de Vries, K. D.; Del Peral, L.; Del Río, M.; Deligny, O.; Dembinski, H.; Dhital, N.; di Giulio, C.; Díaz Castro, M. L.; Diep, P. N.; Diogo, F.; Dobrigkeit, C.; Docters, W.; D'Olivo, J. C.; Dong, P. N.; Dorofeev, A.; Dos Anjos, J. C.; Dova, M. T.; D'Urso, D.; Dutan, I.; Ebr, J.; Engel, R.; Erdmann, M.; Escobar, C. O.; Espadanal, J.; Etchegoyen, A.; Facal San Luis, P.; Fajardo Tapia, I.; Falcke, H.; Farrar, G.; Fauth, A. C.; Fazzini, N.; Ferguson, A. P.; Fick, B.; Filevich, A.; Filipcic, A.; Fliescher, S.; Fracchiolla, C. E.; Fraenkel, E. D.; Fratu, O.; Fröhlich, U.; Fuchs, B.; Gaior, R.; Gamarra, R. F.; Gambetta, S.; García, B.; Garcia Roca, S. T.; Garcia-Gamez, D.; Garcia-Pinto, D.; Gascon, A.; Gemmeke, H.; Ghia, P. L.; Giaccari, U.; Giller, M.; Glass, H.; Gold, M. S.; Golup, G.; Gomez Albarracin, F.; Gómez Berisso, M.; Gómez Vitale, P. F.; Gonçalves, P.; Gonzalez, D.; Gonzalez, J. G.; Gookin, B.; Gorgi, A.; Gouffon, P.; Grashorn, E.; Grebe, S.; Griffith, N.; Grigat, M.; Grillo, A. F.; Guardincerri, Y.; Guarino, F.; Guedes, G. P.; Guzman, A.; Hansen, P.; Harari, D.; Harmsma, S.; Harrison, T. A.; Harton, J. L.; Haungs, A.; Hebbeker, T.; Heck, D.; Herve, A. E.; Hojvat, C.; Hollon, N.; Holmes, V. C.; Homola, P.; Hörandel, J. R.; Horneffer, A.; Horvath, P.; Hrabovský, M.; Huber, D.; Huege, T.; Insolia, A.; Ionita, F.; Italiano, A.; Jarne, C.; Jiraskova, S.; Josebachuili, M.; Kadija, K.; Kampert, K. H.; Karhan, P.; Kasper, P.; Kégl, B.; Keilhauer, B.; Keivani, A.; Kelley, J. L.; Kemp, E.; Kieckhafer, R. M.; Klages, H. O.; Kleifges, M.; Kleinfeller, J.; Knapp, J.; Koang, D.-H.; Kotera, K.; Krohm, N.; Krömer, O.; Kruppke-Hansen, D.; Kuehn, F.; Kuempel, D.; Kulbartz, J. K.; Kunka, N.; La Rosa, G.; Lachaud, C.; Lauer, R.; Lautridou, P.; Le Coz, S.; Leão, M. S. A. B.; Lebrun, D.; Lebrun, P.; Leigui de Oliveira, M. A.; Letessier-Selvon, A.; Lhenry-Yvon, I.; Link, K.; López, R.; Lopez Agüera, A.; Louedec, K.; Lozano Bahilo, J.; Lu, L.; Lucero, A.; Ludwig, M.; Lyberis, H.; Macolino, C.; Maldera, S.; Mandat, D.; Mantsch, P.; Mariazzi, A. G.; Marin, J.; Marin, V.; Maris, I. C.; Marquez Falcon, H. R.; Marsella, G.; Martello, D.; Martin, L.; Martinez, H.; Martínez Bravo, O.; Mathes, H. J.; Matthews, J.; Matthews, J. A. J.; Matthiae, G.; Maurel, D.; Maurizio, D.; Mazur, P. O.; Medina-Tanco, G.; Melissas, M.; Melo, D.; Menichetti, E.; Menshikov, A.; Mertsch, P.; Meurer, C.; Micanovic, S.; Micheletti, M. I.; Miramonti, L.; Molina-Bueno, L.; Mollerach, S.; Monasor, M.; Monnier Ragaigne, D.; Montanet, F.; Morales, B.; Morello, C.; Moreno, E.; Moreno, J. C.; Mostafá, M.; Moura, C. A.; Muller, M. A.; Müller, G.; Münchmeyer, M.; Mussa, R.; Navarra, G.; Navarro, J. L.; Navas, S.; Necesal, P.; Nellen, L.; Nelles, A.; Neuser, J.; Newton, D.; Nhung, P. T.; Niechciol, M.; Niemietz, L.; Nierstenhoefer, N.; Nitz, D.; Nosek, D.; Nožka, L.; Nyklicek, M.; Oehlschläger, J.; Olinto, A.; Ortiz, M.; Pacheco, N.; Pakk Selmi-Dei, D.; Palatka, M.; Pallotta, J.; Palmieri, N.; Parente, G.; Parizot, E.; Parra, A.; Pastor, S.; Paul, T.; Pech, M.; Pekala, J.; Pelayo, R.; Pepe, I. M.; Perrone, L.; Pesce, R.; Petermann, E.; Petrera, S.; Petrinca, P.; Petrolini, A.; Petrov, Y.; Pfendner, C.; Piegaia, R.; Pierog, T.; Pieroni, P.; Pimenta, M.; Pirronello, V.; Platino, M.; Ponce, V. H.; Pontz, M.; Porcelli, A.; Privitera, P.; Prouza, M.; Quel, E. J.; Querchfeld, S.; Rautenberg, J.; Ravel, O.; Ravignani, D.; Revenu, B.; Ridky, J.; Riggi, S.; Risse, M.; Ristori, P.; Rivera, H.; Rizi, V.; Roberts, J.; Rodrigues de Carvalho, W.; Rodriguez, G.; Rodriguez Martino, J.; Rodriguez Rojo, J.; Rodriguez-Cabo, I.; Rodríguez-Frías, M. D.; Ros, G.; Rosado, J.; Rossler, T.; Roth, M.; Rouillé-D'Orfeuil, B.; Roulet, E.; Rovero, A. C.; Rühle, C.; Saftoiu, A.; Salamida, F.; Salazar, H.; Salesa Greus, F.; Salina, G.; Sánchez, F.; Santo, C. E.; Santos, E.; Santos, E. M.; Sarazin, F.; Sarkar, B.; Sarkar, S.; Sato, R.; Scharf, N.; Scherini, V.; Schieler, H.; Schiffer, P.; Schmidt, A.; Scholten, O.; Schoorlemmer, H.; Schovancova, J.; Schovánek, P.; Schröder, F.; Schulte, S.; Schuster, D.; Sciutto, S. J.; Scuderi, M.; Segreto, A.; Settimo, M.; Shadkam, A.; Shellard, R. C.; Sidelnik, I.; Sigl, G.; Silva Lopez, H. H.; Sima, O.; Smialkowski, A.; Šmída, R.; Snow, G. R.; Sommers, P.; Sorokin, J.; Spinka, H.; Squartini, R.; Srivastava, Y. N.; Stanic, S.; Stapleton, J.; Stasielak, J.; Stephan, M.; Stutz, A.; Suarez, F.; Suomijärvi, T.; Supanitsky, A. D.; Šuša, T.; Sutherland, M. S.; Swain, J.; Szadkowski, Z.; Szuba, M.; Tapia, A.; Tartare, M.; Tascau, O.; Tavera Ruiz, C. G.; Tcaciuc, R.; Tegolo, D.; Thao, N. T.; Thomas, D.; Tiffenberg, J.; Timmermans, C.; Tkaczyk, W.; Todero Peixoto, C. J.; Toma, G.; Tomé, B.; Tonachini, A.; Travnicek, P.; Tridapalli, D. B.; Tristram, G.; Trovato, E.; Tueros, M.; Ulrich, R.; Unger, M.; Urban, M.; Valdés Galicia, J. F.; Valiño, I.; Valore, L.; van den Berg, A. M.; Varela, E.; Vargas Cárdenas, B.; Vázquez, J. R.; Vázquez, R. A.; Veberic, D.; Verzi, V.; Vicha, J.; Videla, M.; Villaseñor, L.; Wahlberg, H.; Wahrlich, P.; Wainberg, O.; Walz, D.; Watson, A. A.; Weber, M.; Weidenhaupt, K.; Weindl, A.; Werner, F.; Westerhoff, S.; Whelan, B. J.; Widom, A.; Wieczorek, G.; Wiencke, L.; Wilczynska, B.; Wilczynski, H.; Will, M.; Williams, C.; Winchen, T.; Wommer, M.; Wundheiler, B.; Yamamoto, T.; Yapici, T.; Younk, P.; Yuan, G.; Yushkov, A.; Zamorano, B.; Zas, E.; Zavrtanik, D.; Zavrtanik, M.; Zaw, I.; Zepeda, A.; Zhu, Y.; Zimbres Silva, M.; Ziolkowski, M.

    2012-01-01

    The Surface Detector of the Pierre Auger Observatory is sensitive to neutrinos of all flavours above 0.1 EeV. These interact through charged and neutral currents in the atmosphere giving rise to extensive air showers. When interacting deeply in the atmosphere at nearly horizontal incidence, neutrinos can be distinguished from regular hadronic cosmic rays by the broad time structure of their shower signals in the water-Cherenkov detectors. In this paper we present for the first time an analysis based on down-going neutrinos. We describe the search procedure, the possible sources of background, the method to compute the exposure and the associated systematic uncertainties. No candidate neutrinos have been found in data collected from 1 January 2004 to 31 May 2010. Assuming an E^-2 differential energy spectrum the limit on the single flavour neutrino is (E^2 * dN/dE) < 1.74x10^-7 GeV cm^-2 s^-1 sr^-1 at 90% C.L. in the energy range 1x10^17 eV < E < 1x10^20 eV.

  5. Shape based indexing for faster search of RNA family databases.

    PubMed

    Janssen, Stefan; Reeder, Jens; Giegerich, Robert

    2008-02-29

    Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally annotated RNA families. Unfortunately, searching for new family members using covariance models (CMs) is very time consuming. Filtering approaches that use the sequence conservation to reduce the number of CM searches, are fast, but it is unknown to which sacrifice. We present a new filtering approach, which exploits the family specific secondary structure and significantly reduces the number of CM searches. The filter eliminates approximately 85% of the queries and discards only 2.6% true positives when evaluating Rfam against itself. First results also capture previously undetected non-coding RNAs in a recent human RNAz screen. The RNA shape index filter (RNAsifter) is based on the following rationale: An RNA family is characterised by structure, much more succinctly than by sequence content. Structures of individual family members, which naturally have different length and sequence composition, may exhibit structural variation in detail, but overall, they have a common shape in a more abstract sense. Given a fixed release of the Rfam data base, we can compute these abstract shapes for all families. This is called a shape index. If a query sequence belongs to a certain family, it must be able to fold into the family shape with reasonable free energy. Therefore, rather than matching the query against all families in the data base, we can first (and quickly) compute its feasible shape(s), and use the shape index to access only those families where a good match is possible due to a common shape with the query.

  6. Where Is It? How Deaf Adolescents Complete Fact-Based Internet Search Tasks

    ERIC Educational Resources Information Center

    Smith, Chad E.

    2007-01-01

    An exploratory study was designed to describe Internet search behaviors of deaf adolescents who used Internet search engines to complete fact-based search tasks. The study examined search behaviors of deaf high school students such as query formation, query modification, Web site identification, and Web site selection. Consisting of two fact-based…

  7. A parent body search across several video meteor data bases

    NASA Astrophysics Data System (ADS)

    Šegon, D.; Gural, P.; Andreić, Ž.; Skokić, I.; Korlević, K.; Vida, D.; Novoselnik, F.

    2014-07-01

    A meteor stream search that uses all the known near-Earth objects (NEOs) as parent bodies, with their individual orbital elements as the starting point, has found statistically significant associations when applied to video meteor data bases. By using the combined CMN-SonotaCo data sets containing 133,652 video meteor orbits, 30 comets were associated with meteor showers of which only 23 were previously listed in the IAU MDC data base. Additionally, 43 asteroids with inclinations over 15 degrees may be associated to streams containing ten or more meteor orbits, each possibly representing a new meteor shower. Lastly, by using a modified search that compared the orbital similarity of each meteor to all other video meteors in the data base, 1093 groupings with more than ten meteors were found that may be indicative of several new minor showers. Of those groups, 6 new showers were found to be potentially associated to a parent body. Several dozen additional groups are planned for publication and submittal to the IAU for their consideration as newly discovered streams. Altogether 56,486 (42%) of the meteors in the combined video meteor data base are in one of the meteor stream groupings found, while the rest are likely sporadics. Further analysis is needed to prove that the groupings found are indeed minor showers.

  8. Visual tracking method based on cuckoo search algorithm

    NASA Astrophysics Data System (ADS)

    Gao, Ming-Liang; Yin, Li-Ju; Zou, Guo-Feng; Li, Hai-Tao; Liu, Wei

    2015-07-01

    Cuckoo search (CS) is a new meta-heuristic optimization algorithm that is based on the obligate brood parasitic behavior of some cuckoo species in combination with the Lévy flight behavior of some birds and fruit flies. It has been found to be efficient in solving global optimization problems. An application of CS is presented to solve the visual tracking problem. The relationship between optimization and visual tracking is comparatively studied and the parameters' sensitivity and adjustment of CS in the tracking system are experimentally studied. To demonstrate the tracking ability of a CS-based tracker, a comparative study of tracking accuracy and speed of the CS-based tracker with six "state-of-art" trackers, namely, particle filter, meanshift, PSO, ensemble tracker, fragments tracker, and compressive tracker are presented. Comparative results show that the CS-based tracker outperforms the other trackers.

  9. Parallel Harmony Search Based Distributed Energy Resource Optimization

    SciTech Connect

    Ceylan, Oguzhan; Liu, Guodong; Tomsovic, Kevin

    2015-01-01

    This paper presents a harmony search based parallel optimization algorithm to minimize voltage deviations in three phase unbalanced electrical distribution systems and to maximize active power outputs of distributed energy resources (DR). The main contribution is to reduce the adverse impacts on voltage profile during a day as photovoltaics (PVs) output or electrical vehicles (EVs) charging changes throughout a day. The IEEE 123- bus distribution test system is modified by adding DRs and EVs under different load profiles. The simulation results show that by using parallel computing techniques, heuristic methods may be used as an alternative optimization tool in electrical power distribution systems operation.

  10. Supporting Ontology-based Keyword Search over Medical Databases

    PubMed Central

    Kementsietsidis, Anastasios; Lim, Lipyeow; Wang, Min

    2008-01-01

    The proliferation of medical terms poses a number of challenges in the sharing of medical information among different stakeholders. Ontologies are commonly used to establish relationships between different terms, yet their role in querying has not been investigated in detail. In this paper, we study the problem of supporting ontology-based keyword search queries on a database of electronic medical records. We present several approaches to support this type of queries, study the advantages and limitations of each approach, and summarize the lessons learned as best practices. PMID:18998839

  11. Dynamic clinical data mining: search engine-based decision support.

    PubMed

    Celi, Leo Anthony; Zimolzak, Andrew J; Stone, David J

    2014-06-23

    The research world is undergoing a transformation into one in which data, on massive levels, is freely shared. In the clinical world, the capture of data on a consistent basis has only recently begun. We propose an operational vision for a digitally based care system that incorporates data-based clinical decision making. The system would aggregate individual patient electronic medical data in the course of care; query a universal, de-identified clinical database using modified search engine technology in real time; identify prior cases of sufficient similarity as to be instructive to the case at hand; and populate the individual patient's electronic medical record with pertinent decision support material such as suggested interventions and prognosis, based on prior outcomes. Every individual's course, including subsequent outcomes, would then further populate the population database to create a feedback loop to benefit the care of future patients.

  12. Why Publish?

    ERIC Educational Resources Information Center

    Kaye, Sharon

    2008-01-01

    In humanities, there does not seem to be any good reason to privilege the academic journal over other venues. If the goal of humanities publishing is to spread new ideas, then it seems that creating a popular Internet blog would be the better choice. However, the goal of humanities publishing is not just to spread new ideas, but to spread "good"…

  13. Development and empirical user-centered evaluation of semantically-based query recommendation for an electronic health record search engine.

    PubMed

    Hanauer, David A; Wu, Danny T Y; Yang, Lei; Mei, Qiaozhu; Murkowski-Steffy, Katherine B; Vydiswaran, V G Vinod; Zheng, Kai

    2017-03-01

    The utility of biomedical information retrieval environments can be severely limited when users lack expertise in constructing effective search queries. To address this issue, we developed a computer-based query recommendation algorithm that suggests semantically interchangeable terms based on an initial user-entered query. In this study, we assessed the value of this approach, which has broad applicability in biomedical information retrieval, by demonstrating its application as part of a search engine that facilitates retrieval of information from electronic health records (EHRs). The query recommendation algorithm utilizes MetaMap to identify medical concepts from search queries and indexed EHR documents. Synonym variants from UMLS are used to expand the concepts along with a synonym set curated from historical EHR search logs. The empirical study involved 33 clinicians and staff who evaluated the system through a set of simulated EHR search tasks. User acceptance was assessed using the widely used technology acceptance model. The search engine's performance was rated consistently higher with the query recommendation feature turned on vs. off. The relevance of computer-recommended search terms was also rated high, and in most cases the participants had not thought of these terms on their own. The questions on perceived usefulness and perceived ease of use received overwhelmingly positive responses. A vast majority of the participants wanted the query recommendation feature to be available to assist in their day-to-day EHR search tasks. Challenges persist for users to construct effective search queries when retrieving information from biomedical documents including those from EHRs. This study demonstrates that semantically-based query recommendation is a viable solution to addressing this challenge. Published by Elsevier Inc.

  14. New Architectures for Presenting Search Results Based on Web Search Engines Users Experience

    ERIC Educational Resources Information Center

    Martinez, F. J.; Pastor, J. A.; Rodriguez, J. V.; Lopez, Rosana; Rodriguez, J. V., Jr.

    2011-01-01

    Introduction: The Internet is a dynamic environment which is continuously being updated. Search engines have been, currently are and in all probability will continue to be the most popular systems in this information cosmos. Method: In this work, special attention has been paid to the series of changes made to search engines up to this point,…

  15. An ontology-based search engine for digital reconstructions of neuronal morphology.

    PubMed

    Polavaram, Sridevi; Ascoli, Giorgio A

    2017-06-01

    Neuronal morphology is extremely diverse across and within animal species, developmental stages, brain regions, and cell types. This diversity is functionally important because neuronal structure strongly affects synaptic integration, spiking dynamics, and network connectivity. Digital reconstructions of axonal and dendritic arbors are thus essential to quantify and model information processing in the nervous system. NeuroMorpho.Org is an established repository containing tens of thousands of digitally reconstructed neurons shared by several hundred laboratories worldwide. Each neuron is annotated with specific metadata based on the published references and additional details provided by data owners. The number of represented metadata concepts has grown over the years in parallel with the increase of available data. Until now, however, the lack of standardized terminologies and of an adequately structured metadata schema limited the effectiveness of user searches. Here we present a new organization of NeuroMorpho.Org metadata grounded on a set of interconnected hierarchies focusing on the main dimensions of animal species, anatomical regions, and cell types. We have comprehensively mapped each metadata term in NeuroMorpho.Org to this formal ontology, explicitly resolving all ambiguities caused by synonymy and homonymy. Leveraging this consistent framework, we introduce OntoSearch, a powerful functionality that seamlessly enables retrieval of morphological data based on expert knowledge and logical inferences through an intuitive string-based user interface with auto-complete capability. In addition to returning the data directly matching the search criteria, OntoSearch also identifies a pool of possible hits by taking into consideration incomplete metadata annotation.

  16. Where is it? How deaf adolescents complete fact-based internet search tasks.

    PubMed

    Smith, Chad E

    An exploratory study was designed to describe Internet search behaviors of deaf adolescents who used Internet search engines to complete fact-based search tasks. The study examined search behaviors of deaf high school students such as query formation, query modification, Web site identification, and Web site selection. Consisting of two fact-based search tasks, the study was done in four regional day school programs for the deaf. As students conducted two search tasks, they completed task analyses of the selected Web sites and gave reasons for their selections. The research also identified the processes used by deaf students to compensate for limited English reading abilities while navigating search engines results that were typically written well above deaf students' average reading level. The results demonstrated that deaf adolescents were unable to initiate, conduct, analyze, or validate effective Internet searches in response to fact-based search tasks.

  17. Bibliotherapy and information prescriptions: a summary of the published evidence-base and recommendations from past and ongoing Books on Prescription projects.

    PubMed

    Chamberlain, D; Heaps, D; Robert, I

    2008-01-01

    This paper summarizes the published evidence and reports from ongoing and completed projects that used Bibliotherapy and Information Prescription to deliver patient care. A literature search was conducted and relevant papers were summarized into: type of study, type of Bibliotherapy, client group and recommendations. In total, 65 papers were considered with 57 reviewed. A survey was also sent to Library Authorities subscribing to national survey standards asking for details about delivery of Information Prescription projects. There were 21 returned surveys. The experiences and recommendations were then summarized. The aim of the paper is to collate the evidence-base of written research and the experience and recommendations of projects into an easy format so that practitioners interested in using Bibliotherapy/Information Prescription/Books on Prescription have an understanding what they are, the extent of the evidence-base to inform practice, and highlight gaps in the research.

  18. Local search to improve coordinate-based task mapping

    SciTech Connect

    Balzuweit, Evan; Bunde, David P.; Leung, Vitus J.; Finley, Austin; Lee, Alan C. S.

    2015-10-31

    We present a local search strategy to improve the coordinate-based mapping of a parallel job’s tasks to the MPI ranks of its parallel allocation in order to reduce network congestion and the job’s communication time. The goal is to reduce the number of network hops between communicating pairs of ranks. Our target is applications with a nearest-neighbor stencil communication pattern running on mesh systems with non-contiguous processor allocation, such as Cray XE and XK Systems. Utilizing the miniGhost mini-app, which models the shock physics application CTH, we demonstrate that our strategy reduces application running time while also reducing the runtime variability. Furthermore, we further show that mapping quality can vary based on the selected allocation algorithm, even between allocation algorithms of similar apparent quality.

  19. Local search to improve coordinate-based task mapping

    DOE PAGES

    Balzuweit, Evan; Bunde, David P.; Leung, Vitus J.; ...

    2015-10-31

    We present a local search strategy to improve the coordinate-based mapping of a parallel job’s tasks to the MPI ranks of its parallel allocation in order to reduce network congestion and the job’s communication time. The goal is to reduce the number of network hops between communicating pairs of ranks. Our target is applications with a nearest-neighbor stencil communication pattern running on mesh systems with non-contiguous processor allocation, such as Cray XE and XK Systems. Utilizing the miniGhost mini-app, which models the shock physics application CTH, we demonstrate that our strategy reduces application running time while also reducing the runtimemore » variability. Furthermore, we further show that mapping quality can vary based on the selected allocation algorithm, even between allocation algorithms of similar apparent quality.« less

  20. Text Clustering Based on the User Search Intention

    NASA Astrophysics Data System (ADS)

    Liu, Wenjing; Zhou, Yanquan; Ren, Fuji

    This paper presents a novel algorithm of Text Clustering. With the popularity of the Internet, text information on the web shows explosive growth trend. Text Clustering technology as a method of unsupervised machine learning, which does not need the training process and pre-manual tagging, so Text Clustering is an effective way for dealing with massive text messages. The traditional Text Clustering is based on the content of the article, and they think that the articles which belong to the same class have the greater similarity. In this paper, we extracted label word from the summary information returned by search engine. Then did hierarchical clustering based on the text feature of the label word. Experiment shows that the algorithm is feasible.

  1. [Influence of journals indexed by Science Citation Index (SCI) on Chinese medical journals based on the data of published articles by Chinese authors from 2000 - 2009].

    PubMed

    Fu, Xiao-Xia; Li, Gui-Cun

    2011-04-01

    This study was designed to investigate the influence of journals indexed by Science Citation Index (SCI) on Chinese medical journals. Articles on medicine written by Chinese and the journals that published these articles from 2000 to 2009 were searched using Science Citation Index Expanded (SCI-E) database, and the status and variation tendency of the impact factors (IF) of these journals were analyzed. Data of articles on medicine included Chinese Scientific and Technical Paper and Citations Data (CSTPCD) from 2000 to 2008 were searched (the data of 2009 have not been released). The included articles and the time-dependent changing profile were studied. These outcomes were evaluated as the fixed base relative or link relative when compared with the data of 2000 or those of last year, respectively. Geometric mean was used when mean increase was calculated and IF distribution was described with median. Totally 3774 articles from China were published by journals indexed by SCI-E in 2000, and the number of articles published by Chinese authors increased every year. In 2008, 16 714 articles were indexed by SCI-E, 442.87% higher than those of 2000. The increment was 161.54% higher than that of articles published in the journals indexed by CSTPCD (281.33%) during the same period. From 2000 to 2009, the geometric mean of increase in the number of published articles from China in journals indexed by SCI-E was 20.87% but it was 18.21% in CSTPCD. From 2000 to 2009, the median of IF of SCI-E indexed journals that published Chinese medical articles was 1.866, 2.073, 2.390, 2.702, 2.409, 2.496, 2.380, 2.218, 2.280 and 2.331, respectively, and they did not increase or even decreased. The number of the articles indexed by SCI-E increased year by year, much faster than that of CSTPCD. However, it does not necessarily mean the increase in impact.

  2. Managing Online Search Statistics with dBASE III Plus.

    ERIC Educational Resources Information Center

    Speer, Susan C.

    1987-01-01

    Describes a computer program designed to manage statistics about online searches which reports the number of searches by vendor, purpose, and librarian; calculates charges to departments and individuals; and prints monthly invoices to users with standing accounts. (CLB)

  3. A Systematic Understanding of Successful Web Searches in Information-Based Tasks

    ERIC Educational Resources Information Center

    Zhou, Mingming

    2013-01-01

    The purpose of this study is to research how Chinese university students solve information-based problems. With the Search Performance Index as the measure of search success, participants were divided into high, medium and low-performing groups. Based on their web search logs, these three groups were compared along five dimensions of the search…

  4. A Systematic Understanding of Successful Web Searches in Information-Based Tasks

    ERIC Educational Resources Information Center

    Zhou, Mingming

    2013-01-01

    The purpose of this study is to research how Chinese university students solve information-based problems. With the Search Performance Index as the measure of search success, participants were divided into high, medium and low-performing groups. Based on their web search logs, these three groups were compared along five dimensions of the search…

  5. Substance identification based on transmission THz spectra using library search

    NASA Astrophysics Data System (ADS)

    Platte, Frank; Heise, H. Michael

    2014-09-01

    Over recent years terahertz spectroscopy has become a new tool for the characterization of solid materials, in particular for investigating polymorphism and crystallinity in pharmaceutics. Search strategies have been tested for THz spectra of various organic compounds with their spectra taken from the Riken database (http://www.riken.jp), using the GRAMS spectroscopy software. A subset of the entire database was used, which had been processed by removal of atmospheric water vapour lines and smoothing applied based on Savitzky-Golay convolution or time domain filtering. The spectral range available for all library substances was restricted to an interval from 0.9 to 4.5 THz (30-150 cm-1). The number of vibrational bands within this spectral range is much reduced compared with mid-infrared or Raman spectra. The appropriateness of spectral pre-treatment is demonstrated with regard to reliability and robustness of the search methods. In particular, time-domain filters for smoothing and pre-treatment by the removal of water lines and etalon effects have been successfully tested in combination with least squares and correlation methods. With these insights, applications for substance identification, especially for the pharmaceutical industry, may be enlarged.

  6. Biobotic insect swarm based sensor networks for search and rescue

    NASA Astrophysics Data System (ADS)

    Bozkurt, Alper; Lobaton, Edgar; Sichitiu, Mihail; Hedrick, Tyson; Latif, Tahmid; Dirafzoon, Alireza; Whitmire, Eric; Verderber, Alexander; Marin, Juan; Xiong, Hong

    2014-06-01

    The potential benefits of distributed robotics systems in applications requiring situational awareness, such as search-and-rescue in emergency situations, are indisputable. The efficiency of such systems requires robotic agents capable of coping with uncertain and dynamic environmental conditions. For example, after an earthquake, a tremendous effort is spent for days to reach to surviving victims where robotic swarms or other distributed robotic systems might play a great role in achieving this faster. However, current technology falls short of offering centimeter scale mobile agents that can function effectively under such conditions. Insects, the inspiration of many robotic swarms, exhibit an unmatched ability to navigate through such environments while successfully maintaining control and stability. We have benefitted from recent developments in neural engineering and neuromuscular stimulation research to fuse the locomotory advantages of insects with the latest developments in wireless networking technologies to enable biobotic insect agents to function as search-and-rescue agents. Our research efforts towards this goal include development of biobot electronic backpack technologies, establishment of biobot tracking testbeds to evaluate locomotion control efficiency, investigation of biobotic control strategies with Gromphadorhina portentosa cockroaches and Manduca sexta moths, establishment of a localization and communication infrastructure, modeling and controlling collective motion by learning deterministic and stochastic motion models, topological motion modeling based on these models, and the development of a swarm robotic platform to be used as a testbed for our algorithms.

  7. Remotely sensed image processing service composition based on heuristic search

    NASA Astrophysics Data System (ADS)

    Yang, Xiaoxia; Zhu, Qing; Li, Hai-feng; Zhao, Wen-hao

    2008-12-01

    As remote sensing technology become ever more powerful with multi-platform and multi-sensor, it has been widely recognized for contributing to geospatial information efforts. Because the remotely sensed image processing demands large-scale, collaborative processing and massive storage capabilities to satisfy the increasing demands of various applications, the effect and efficiency of the remotely sensed image processing is far from the user's expectation. The emergence of Service Oriented Architecture (SOA) may make this challenge manageable. It encapsulate all processing function into services and recombine them with service chain. The service composition on demand has become a hot topic. Aiming at the success rate, quality and efficiency of processing service composition for remote sensing application, a remote sensed image processing service composition method is proposed in this paper. It composes services for a user requirement through two steps: 1) dynamically constructs a complete service dependency graph for user requirement on-line; 2) AO* based heuristic searches for optimal valid path in service dependency graph. These services within the service dependency graph are considered relevant to the specific request, instead of overall registered services. The second step, heuristic search is a promising approach for automated planning. Starting with the initial state, AO* uses a heuristic function to select states until the user requirement is reached. Experimental results show that this method has a good performance even the repository has a large number of processing services.

  8. A new search algorithm based on probability in intrusion detection

    NASA Astrophysics Data System (ADS)

    Sun, Jianhua; Jin, Hai; Han, Zongfen; Chen, Hao; Yang, Yanping

    2004-04-01

    Detection rate is vital to intrusion detection. We propose a new search algorithm base on probability to speed up the process rate for a novel compound intrusion detection system (CIDS). We employ an improved Bayesian decision theorem to build this compound model. The improved Bayesian decision theorem brings four profits to this model. The first is to eliminate the flaws of a narrow definition for normal patterns and intrusion patterns. The second is to extend the known intrusions patterns to novel intrusions patterns. The third is to reduce risks that detecting intrusion brings to system. The last is to offer a method to build a compound intrusion detection model that integrates misuse intrusion detection system (MIDS) and anomaly intrusion detection system (AIDS). During the experiment of this model, we find that different system calls sequences have different probabilities. So the sequences with high probabilities are compared prior to an observed sequence, which is the foundation of our new search algorithm. We evaluate the performance of the new algorithm using numerical results, and the results show this new algorithm increases the detection rate.

  9. Clause states based configuration checking in local search for satisfiability.

    PubMed

    Luo, Chuan; Cai, Shaowei; Su, Kaile; Wu, Wei

    2015-05-01

    Two-mode stochastic local search (SLS) and focused random walk (FRW) are the two most influential paradigms of SLS algorithms for the propositional satisfiability (SAT) problem. Recently, an interesting idea called configuration checking (CC) was proposed to handle the cycling problem in SLS. The CC idea has been successfully used to improve SLS algorithms for SAT, resulting in state-of-the-art solvers. Previous CC strategies for SAT are based on neighboring variables, and prove successful in two-mode SLS algorithms. However, this kind of neighboring variables based CC strategy is not suitable for improving FRW algorithms. In this paper, we propose a new CC strategy which is based on clause states. We apply this clause states based CC (CSCC) strategy to both two-mode SLS and FRW paradigms. Our experiments show that the CSCC strategy is effective on both paradigms. Furthermore, our developed FRW algorithms based on CSCC achieve state-of-the-art performance on a broad range of random SAT benchmarks.

  10. Axion search by laser-based experiment OSQAR

    NASA Astrophysics Data System (ADS)

    Sulc, M.; Pugnat, P.; Ballou, R.; Deferne, G.; Duvillaret, L.; Flekova, L.; Finger, M.; Finger, M.; Hosek, J.; Husek, T.; Jost, R.; Kral, M.; Kunc, S.; Macuchova, K.; Meissner, K. A.; Morville, J.; Romanini, D.; Schott, M.; Siemko, A.; Slunecka, M.; Vitrant, G.; Zicha, J.

    2013-08-01

    Laser-based experiment OSQAR in CERN is aimed to the search of the axions by two methods. The photon regeneration experiment is using two LHC dipole magnets of the length 14.3 m and magnetic field 9.5 T equipped with an optical barrier at the end of the first magnet. It looks as light shining through the wall. No excess of events above the background was detected at this arrangement. Nevertheless, this result extends the exclusion region for the axion mass. The second method wants to measure the ultra-fine vacuum magnetic birefringence for the first time. An optical scheme with electro-optical modulator has been proposed, validated and subsequently improved. Cotton-Mouton constant for air was determined in this experiment setup.

  11. Gaussian model-based partitioning using iterated local search.

    PubMed

    Brusco, Michael J; Shireman, Emilie; Steinley, Douglas; Brudvig, Susan; Cradit, J Dennis

    2017-02-01

    The emergence of Gaussian model-based partitioning as a viable alternative to K-means clustering fosters a need for discrete optimization methods that can be efficiently implemented using model-based criteria. A variety of alternative partitioning criteria have been proposed for more general data conditions that permit elliptical clusters, different spatial orientations for the clusters, and unequal cluster sizes. Unfortunately, many of these partitioning criteria are computationally demanding, which makes the multiple-restart (multistart) approach commonly used for K-means partitioning less effective as a heuristic solution strategy. As an alternative, we propose an approach based on iterated local search (ILS), which has proved effective in previous combinatorial data analysis contexts. We compared multistart, ILS and hybrid multistart-ILS procedures for minimizing a very general model-based criterion that assumes no restrictions on cluster size or within-group covariance structure. This comparison, which used 23 data sets from the classification literature, revealed that the ILS and hybrid heuristics generally provided better criterion function values than the multistart approach when all three methods were constrained to the same 10-min time limit. In many instances, these differences in criterion function values reflected profound differences in the partitions obtained.

  12. Omicseq: a web-based search engine for exploring omics datasets.

    PubMed

    Sun, Xiaobo; Pittard, William S; Xu, Tianlei; Chen, Li; Zwick, Michael E; Jiang, Xiaoqian; Wang, Fusheng; Qin, Zhaohui S

    2017-04-10

    The development and application of high-throughput genomics technologies has resulted in massive quantities of diverse omics data that continue to accumulate rapidly. These rich datasets offer unprecedented and exciting opportunities to address long standing questions in biomedical research. However, our ability to explore and query the content of diverse omics data is very limited. Existing dataset search tools rely almost exclusively on the metadata. A text-based query for gene name(s) does not work well on datasets wherein the vast majority of their content is numeric. To overcome this barrier, we have developed Omicseq, a novel web-based platform that facilitates the easy interrogation of omics datasets holistically to improve 'findability' of relevant data. The core component of Omicseq is trackRank, a novel algorithm for ranking omics datasets that fully uses the numerical content of the dataset to determine relevance to the query entity. The Omicseq system is supported by a scalable and elastic, NoSQL database that hosts a large collection of processed omics datasets. In the front end, a simple, web-based interface allows users to enter queries and instantly receive search results as a list of ranked datasets deemed to be the most relevant. Omicseq is freely available at http://www.omicseq.org. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  13. The effects of mulching on soil erosion by water. A review based on published data

    NASA Astrophysics Data System (ADS)

    Prosdocimi, Massimo; Jordán, Antonio; Tarolli, Paolo; Cerdà, Artemi

    2016-04-01

    lands, post-fire affected areas and anthropic sites. Data published in literature have been collected. The results proved the beneficial effects of mulching on soil erosion by water in all the contexts considered, with reduction rates in average sediment concentration, soil loss and runoff volume that, in some cases, exceeded 90%. Furthermore, in most cases, mulching confirmed to be a relatively inexpensive soil conservation practice that allowed to reduce soil erodibility and surface immediately after its application. References Cerdà, A., 1994. The response of abandoned terraces to simulated rain, in: Rickson, R.J., (Ed.), Conserving Soil Resources: European Perspective, CAB International, Wallingford, pp. 44-55. Cerdà, A., Flanagan, D.C., Le Bissonnais, Y., Boardman, J., 2009. Soil erosion and agriculture. Soil & Tillage Research 106, 107-108. Cerdan, O., Govers, G., Le Bissonnais, Y., Van Oost, K., Poesen, J., Saby, N., Gobin, A., Vacca, A., Quinton, J., Auerwald, K., Klik, A., Kwaad, F.J.P.M., Raclot, D., Ionita, I., Rejman, J., Rousseva, S., Muxart, T., Roxo, M.J., Dostal, T., 2010. Rates and spatial variations of soil erosion in Europe: A study based on erosion plot data. Geomorphology 122, 167-177. García-Orenes, F., Roldán A., Mataix-Solera, J, Cerdà, A., Campoy M, Arcenegui, V., Caravaca F. 2009. Soil structural stability and erosion rates influenced by agricultural management practices in a semi-arid Mediterranean agro-ecosystem. Soil Use and Management 28: 571-579. Hayes, S.A., McLaughlin, R.A., Osmond, D.L., 2005. Polyacrylamide use for erosion and turbidity control on construction sites. Journal of soil and water conservation 60(4):193-199. Jordán, A., Zavala, L.M., Muñoz-Rojas, M., 2011. Mulching, effects on soil physical properties. In: Gliński, J., Horabik, J., Lipiec, J. (Eds.), Encyclopedia of Agrophysics. Springer, Dordrecht, pp. 492-496. Montgomery, D.R., 2007. Soil erosion and agricultural sustainability. PNAS 104, 13268-13272. Prats, S

  14. The effects of visual search efficiency on object-based attention.

    PubMed

    Greenberg, Adam S; Rosen, Maya; Cutrone, Elizabeth; Behrmann, Marlene

    2015-07-01

    The attentional prioritization hypothesis of object-based attention (Shomstein & Yantis in Perception & Psychophysics, 64, 41-51, 2002) suggests a two-stage selection process comprising an automatic spatial gradient and flexible strategic (prioritization) selection. The combined attentional priorities of these two stages of object-based selection determine the order in which participants will search the display for the presence of a target. The strategic process has often been likened to a prioritized visual search. By modifying the double-rectangle cueing paradigm (Egly, Driver, & Rafal in Journal of Experimental Psychology: General, 123, 161-177, 1994) and placing it in the context of a larger-scale visual search, we examined how the prioritization search is affected by search efficiency. By probing both targets located on the cued object and targets external to the cued object, we found that the attentional priority surrounding a selected object is strongly modulated by search mode. However, the ordering of the prioritization search is unaffected by search mode. The data also provide evidence that standard spatial visual search and object-based prioritization search may rely on distinct mechanisms. These results provide insight into the interactions between the mode of visual search and object-based selection, and help define the modulatory consequences of search efficiency for object-based attention.

  15. Program-Based Literacy Materials Catalogue. A Project of the Ontario Regional Literacy Desktop Publishers. First Edition.

    ERIC Educational Resources Information Center

    Churchill, Kevin, Comp.; And Others

    This catalogue, which is intended as a resource for literacy practitioners, contains information about program-based literacy materials produced by Ontario's (Canada) four desktop publishing centers for literacy programs. A total of 148 instructional materials (including materials developed by literacy learners), tutor/practitioner tools, and…

  16. A systematic review of published evidence on expanded endoscopic endonasal skull base surgery and the risk of postoperative seizure.

    PubMed

    Lai, Leon; Morgan, Michael K; Trooboff, Spencer; Harvey, Richard J

    2013-02-01

    Although postoperative seizure is an acknowledged risk following transcranial surgery, the incidence of seizure after removal of intradural pathology via an expanded endoscopic endonasal approach is not well defined. The current study was performed to systematically review the risk of seizure in patients undergoing endoscopic endonasal skull base (EESB) surgery. Embase (1980 to 9 March 2012) and Medline (1950 to 9 March 2012) were searched using a search strategy designed to include any studies that report the perioperative outcomes following EESB surgery. Outcomes of patients undergoing a simple closure of cerebrospinal fluid fistulae or encephaloceles and transellar approaches for pituitary or intrasellar lesions were excluded because this review is focused on large skull base defects. A title search selected those articles relevant to clinical series on expanded endoscopic approaches. A subsequent search of abstracts selected for manuscripts of any report that documented the presence or absence of postoperative seizure. A total of 2234 manuscripts were selected initially and full text analysis produced 67 studies with extractable data regarding the perioperative outcomes for EESB surgery. Of these manuscripts, seven reported the incidence of seizure following EESB procedures. Two of these studies were excluded due to duplication of authorship and institutional data. The overall risk of postoperative seizure following EESB surgery was estimated at 1.1% (six of 530). Subgroup analyses of data revealed that the risk of seizure following an endoscopic endonasal to the anterior cranial base was 2.3% (one patient of 43). For a posterior cranial base approach, the risk of seizure was indeterminate due to deficiency of reporting in the current literature. We concluded that the risk of seizure following an EESB procedure appears to be low (1%). However, the lack of reporting on the incidence of seizures or the use of antiepileptic prophylaxis following EESB procedure is

  17. Part 2: Home-based family caregiving at the end of life: a comprehensive review of published qualitative research (1998-2008).

    PubMed

    Funk, L; Stajduhar, Ki; Toye, C; Aoun, S; Grande, Ge; Todd, Cj

    2010-09-01

    Family caregivers are crucial for supporting home death. We reviewed published qualitative research on home-based family caregiving at end of life (1998-2008), synthesizing key findings and identifying gaps where additional research is needed. Multiple databases were searched and abstracts reviewed for a focus on family caregiving and palliative care; full articles were reviewed to extract data for this review. In total, 105 articles were included. Findings are presented in the following areas: the caregiving experience and contextual features; supporting family caregivers at end of life; caregiving roles and decision-making; and rewards, meaning and coping. We noted a lack of definitional clarity; a reliance on interview methods and descriptive, thematic analyses, and a relative lack of diversity of patient conditions. Research needs are identified in several areas, including the bereavement experience, caregiver ambivalence, access to services, caregiver meaning-making, and relational and contextual influences on family caregiving at end of life.

  18. Part-based deep representation for product tagging and search

    NASA Astrophysics Data System (ADS)

    Chen, Keqing

    2017-06-01

    Despite previous studies, tagging and indexing the product images remain challenging due to the large inner-class variation of the products. In the traditional methods, the quantized hand-crafted features such as SIFTs are extracted as the representation of the product images, which are not discriminative enough to handle the inner-class variation. For discriminative image representation, this paper firstly presents a novel deep convolutional neural networks (DCNNs) architect true pre-trained on a large-scale general image dataset. Compared to the traditional features, our DCNNs representation is of more discriminative power with fewer dimensions. Moreover, we incorporate the part-based model into the framework to overcome the negative effect of bad alignment and cluttered background and hence the descriptive ability of the deep representation is further enhanced. Finally, we collect and contribute a well-labeled shoe image database, i.e., the TBShoes, on which we apply the part-based deep representation for product image tagging and search, respectively. The experimental results highlight the advantages of the proposed part-based deep representation.

  19. Canities Subita: A Reappraisal of Evidence Based on 196 Case Reports Published in the Medical Literature

    PubMed Central

    Nahm, Michael; Navarini, Alexander A; Kelly, Emily Williams

    2013-01-01

    We have reviewed the medical literature on unusually rapid Canities of body hair to assess whether the reported clinical evidence can be explained with the current hypotheses of pathogenetic mechanisms. We screened the medical literature from 1800 onward, searching for as many case reports as possible. We assessed literature in Dutch, English, French, German, Italian and Spanish and included all cases, which contained an explicit mention or description of unusually rapid graying or whitening of hair. Case reports were classified into three categories: Cases are “authenticated” when the authors personally observed the rapid color change, “non-authenticated” when they saw the subject only after the alleged color change and “anecdotal” when authors were told about the case by a third party. In total, we found 196 cases of which 44 were authenticated. These studies reported the graying of human hair in the context of aging, somatic diseases, emotional trauma or stress and psychiatric disorders. Numerous cases involved not only scalp hair, but also beards, eyelashes and other body hair. Several authors stressed that there was no alopecia. Although plausible explanations exist to explain Canities subita occurring together with an effluvium, the observation of viable hair losing color along the axis within a timespan shorter than its growth rate remain as yet unexplained. PMID:24403766

  20. Research methodology search filters: are they effective for locating research for evidence-based veterinary medicine in PubMed?

    PubMed Central

    Murphy, Sarah Anne

    2003-01-01

    Objective: The study examined the effectiveness of research methodology search filters developed by Haynes and colleagues and utilized by the Clinical Query feature of PubMed for locating literature for evidence-based veterinary medicine (EBVM). Methods: A manual review of articles published in 6 commonly read veterinary journals was conducted. Articles were classified by format (original study, review, general article, conference report, decision analysis, and case report) and purpose category (etiology, prognosis, diagnosis, and treatment). Search strategies listed in PubMed's Clinical Query feature were then tested and compared to the manually reviewed data to calculate sensitivity, specificity, and precision. Results: The author manually reviewed 914 articles to identify 702 original studies. Search #1 included terms determined to have the highest sensitivity and returned acceptable sensitivities over 75% for diagnosis and treatment. Search #2 included terms identified as providing the highest specificity and returned results with specificities over 75% for etiology, prognosis, and treatment. Discussion: The low precision for each search prompts the question: Are research methodology search filters practical for locating literature for the practice of EBVM? A study examining terms related to appropriate research methodologies for advanced clinical veterinary research is necessary to develop filters designed to locate literature for EBVM. PMID:14566380

  1. Research methodology search filters: are they effective for locating research for evidence-based veterinary medicine in PubMed?

    PubMed

    Murphy, Sarah Anne

    2003-10-01

    The study examined the effectiveness of research methodology search filters developed by Haynes and colleagues and utilized by the Clinical Query feature of PubMed for locating literature for evidence-based veterinary medicine (EBVM). A manual review of articles published in 6 commonly read veterinary journals was conducted. Articles were classified by format (original study, review, general article, conference report, decision analysis, and case report) and purpose category (etiology, prognosis, diagnosis, and treatment). Search strategies listed in PubMed's Clinical Query feature were then tested and compared to the manually reviewed data to calculate sensitivity, specificity, and precision. The author manually reviewed 914 articles to identify 702 original studies. Search #1 included terms determined to have the highest sensitivity and returned acceptable sensitivities over 75% for diagnosis and treatment. Search #2 included terms identified as providing the highest specificity and returned results with specificities over 75% for etiology, prognosis, and treatment. The low precision for each search prompts the question: Are research methodology search filters practical for locating literature for the practice of EBVM? A study examining terms related to appropriate research methodologies for advanced clinical veterinary research is necessary to develop filters designed to locate literature for EBVM.

  2. GeoSearcher: Location-Based Ranking of Search Engine Results.

    ERIC Educational Resources Information Center

    Watters, Carolyn; Amoudi, Ghada

    2003-01-01

    Discussion of Web queries with geospatial dimensions focuses on an algorithm that assigns location coordinates dynamically to Web sites based on the URL. Describes a prototype search system that uses the algorithm to re-rank search engine results for queries with a geospatial dimension, thus providing an alternative ranking order for search engine…

  3. GeoSearcher: Location-Based Ranking of Search Engine Results.

    ERIC Educational Resources Information Center

    Watters, Carolyn; Amoudi, Ghada

    2003-01-01

    Discussion of Web queries with geospatial dimensions focuses on an algorithm that assigns location coordinates dynamically to Web sites based on the URL. Describes a prototype search system that uses the algorithm to re-rank search engine results for queries with a geospatial dimension, thus providing an alternative ranking order for search engine…

  4. Methodological quality of systematic reviews and clinical trials on women's health published in a Brazilian evidence-based health journal

    PubMed Central

    Macedo, Cristiane Rufino; Riera, Rachel; Torloni, Maria Regina

    2013-01-01

    OBJECTIVES: To assess the quality of systematic reviews and clinical trials on women's health recently published in a Brazilian evidence-based health journal. METHOD: All systematic reviews and clinical trials on women's health published in the last five years in the Brazilian Journal of Evidence-based Health were retrieved. Two independent reviewers critically assessed the methodological quality of reviews and trials using AMSTAR and the Cochrane Risk of Bias Table, respectively. RESULTS: Systematic reviews and clinical trials accounted for less than 10% of the 61 original studies on women's health published in the São Paulo Medical Journal over the last five years. All five reviews were considered to be of moderate quality; the worst domains were publication bias and the appropriate use of study quality in formulating conclusions. All three clinical trials were judged to have a high risk of bias. The participant blinding, personnel and outcome assessors and allocation concealment domains had the worst scores. CONCLUSIONS: Most of the systematic reviews and clinical trials on women's health recently published in a Brazilian evidence-based journal are of low to moderate quality. The quality of these types of studies needs improvement. PMID:23778332

  5. Three dimensional pattern recognition using feature-based indexing and rule-based search

    NASA Astrophysics Data System (ADS)

    Lee, Jae-Kyu

    In flexible automated manufacturing, robots can perform routine operations as well as recover from atypical events, provided that process-relevant information is available to the robot controller. Real time vision is among the most versatile sensing tools, yet the reliability of machine-based scene interpretation can be questionable. The effort described here is focused on the development of machine-based vision methods to support autonomous nuclear fuel manufacturing operations in hot cells. This thesis presents a method to efficiently recognize 3D objects from 2D images based on feature-based indexing. Object recognition is the identification of correspondences between parts of a current scene and stored views of known objects, using chains of segments or indexing vectors. To create indexed object models, characteristic model image features are extracted during preprocessing. Feature vectors representing model object contours are acquired from several points of view around each object and stored. Recognition is the process of matching stored views with features or patterns detected in a test scene. Two sets of algorithms were developed, one for preprocessing and indexed database creation, and one for pattern searching and matching during recognition. At recognition time, those indexing vectors with the highest match probability are retrieved from the model image database, using a nearest neighbor search algorithm. The nearest neighbor search predicts the best possible match candidates. Extended searches are guided by a search strategy that employs knowledge-base (KB) selection criteria. The knowledge-based system simplifies the recognition process and minimizes the number of iterations and memory usage. Novel contributions include the use of a feature-based indexing data structure together with a knowledge base. Both components improve the efficiency of the recognition process by improved structuring of the database of object features and reducing data base size

  6. Publisher's Announcement

    NASA Astrophysics Data System (ADS)

    McGlashan, Yasmin

    2008-01-01

    Article numbering Nuclear Fusion has moved from sequential page numbering to an article numbering system, offering important advantages and flexibility by speeding up the publication process. Papers in different issues or sections can be published online as soon as they are ready, without having to wait for a whole issue or section to be allocated page numbers. The bibliographic citation will change slightly. Articles should be referenced using the six-digit article number in place of a page number, and this number must include any leading zeros. For instance, from this issue: Li G.Q. et al 2008 Nucl. Fusion 48 015001 Articles will continue to be published on the web in advance of the print edition.

  7. Correlation study in skin and eye irritation between rabbits and humans based on published literatures.

    PubMed

    Ishii, Satoko; Ishii, Kaori; Nakadate, Masahiro; Yamasaki, Kanji

    2013-05-01

    The purpose of this study was to investigate the correlations in skin and eye irritations between rabbits and humans using published international databases. We selected 60 and 56 compounds for skin and eye irritation, respectively. When the reactions were divided into irritation-negative or irritation-positive, including corrosion, similar reactions between rabbits and humans were detected for 53 compounds in skin irritation and 54 compounds in eye irritation, showing rates of agreement in skin and eye as 88% and 96%, respectively. These findings revealed that correlation in skin and eye irritations between rabbits and humans were high. However, corrosion was observed in rabbit skin treated with 14 compounds, 4 of which showed similar changes in humans, and in rabbit eyes treated with 9 compounds, 1 of which revealed similar changes in humans. These findings indicated that the incidence of corrosion was higher in rabbits than in humans. Our results showed that the data on rabbit irritations in the skin and eye were useful for identifying risk of irritation in human. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Evidence-based orthodontics. Current statistical trends in published articles in one journal.

    PubMed

    Law, Scott V; Chudasama, Dipak N; Rinchuse, Donald J

    2010-09-01

    To ascertain the number, type, and overall usage of statistics in American Journal of Orthodontics and Dentofacial (AJODO) articles for 2008. These data were then compared to data from three previous years: 1975, 1985, and 2003. The frequency and distribution of statistics used in the AJODO original articles for 2008 were dichotomized into those using statistics and those not using statistics. Statistical procedures were then broadly divided into descriptive statistics (mean, standard deviation, range, percentage) and inferential statistics (t-test, analysis of variance). Descriptive statistics were used to make comparisons. In 1975, 1985, 2003, and 2008, AJODO published 72, 87, 134, and 141 original articles, respectively. The percentage of original articles using statistics was 43.1% in 1975, 75.9% in 1985, 94.0% in 2003, and 92.9% in 2008; original articles using statistics stayed relatively the same from 2003 to 2008, with only a small 1.1% decrease. The percentage of articles using inferential statistical analyses was 23.7% in 1975, 74.2% in 1985, 92.9% in 2003, and 84.4% in 2008. Comparing AJODO publications in 2003 and 2008, there was an 8.5% increase in the use of descriptive articles (from 7.1% to 15.6%), and there was an 8.5% decrease in articles using inferential statistics (from 92.9% to 84.4%).

  9. Seasonal trend analysis of published ground-based and TOMS total ozone data through 1991

    NASA Technical Reports Server (NTRS)

    Reinsel, Gregory C.; Tiao, George C.; Wuebbles, Donald J.; Kerr, James B.; Miller, Alvin J.; Nagatani, Ronald M.; Bishop, Lane; Ying, Lisa H.

    1994-01-01

    A seasonal trend analysis of published Dobson (including stations' newly revised and Brewer-simulated Dobson) total ozone data through 1991 from a network of 56 stations has been performed, using three different data periods. The trend results for the longest data period 1964 - 1991 indicate substantial negative trends in ozone in the higher northern latitudes during the winter and spring seasons, some evidence of negative trend in the higher southern latitudes (30 deg S - 55 deg S) during all seasons, and trends close to zero for all seasons over the 30 deg S - 30 deg N latitude range. For the shortest data period, November 1978 through 1991, there is a clear indication that trends have become more negative in the higher northern latitudes, especially during the winter and spring seasons, and also in the higher southern latitudes in all seasons. A seasonal trend analysis of zonal averages of total ozone mapping spectrometer (TOMS) satellite total ozone data for the comparable period November 1978 through 1991 has also been performed, and moderately good agreement is found between trends in Dobson and TOMS data over this period.

  10. Online Discovery of Search Objectives for Test-Based Problems.

    PubMed

    Liskowski, Paweł; Krawiec, Krzysztof

    2017-01-01

    In test-based problems, commonly approached with competitive coevolutionary algorithms, the fitness of a candidate solution is determined by the outcomes of its interactions with multiple tests. Usually, fitness is a scalar aggregate of interaction outcomes, and as such imposes a complete order on the candidate solutions. However, passing different tests may require unrelated "skills," and candidate solutions may vary with respect to such capabilities. In this study, we provide theoretical evidence that scalar fitness, inherently incapable of capturing such differences, is likely to lead to premature convergence. To mitigate this problem, we propose disco, a method that automatically identifies the groups of tests for which the candidate solutions behave similarly and define the above skills. Each such group gives rise to a derived objective, and these objectives together guide the search algorithm in multi-objective fashion. When applied to several well-known test-based problems, the proposed approach significantly outperforms the conventional two-population coevolution. This opens the door to efficient and generic countermeasures to premature convergence for both coevolutionary and evolutionary algorithms applied to problems featuring aggregating fitness functions.

  11. Research on Chord Searching Algorithm Base on Cache Strategy

    NASA Astrophysics Data System (ADS)

    Jun, Guo; Chen, Chen

    How to improve search efficiency is a core problem in P2P network, Chord is a successful searching algorithm, but its lookup efficiency is lower because finger table has redundant information proposed the recently visited table and improved to gain more useful information in Chord. The simulation experiments show that approach can availably improve the routing efficiently.

  12. Job Search Methods: Consequences for Gender-based Earnings Inequality.

    ERIC Educational Resources Information Center

    Huffman, Matt L.; Torres, Lisa

    2001-01-01

    Data from adults in Atlanta, Boston, and Los Angeles (n=1,942) who searched for work using formal (ads, agencies) or informal (networks) methods indicated that type of method used did not contribute to the gender gap in earnings. Results do not support formal job search as a way to reduce gender inequality. (Contains 55 references.) (SK)

  13. OS2: Oblivious similarity based searching for encrypted data outsourced to an untrusted domain

    PubMed Central

    Pervez, Zeeshan; Ahmad, Mahmood; Khattak, Asad Masood; Ramzan, Naeem

    2017-01-01

    Public cloud storage services are becoming prevalent and myriad data sharing, archiving and collaborative services have emerged which harness the pay-as-you-go business model of public cloud. To ensure privacy and confidentiality often encrypted data is outsourced to such services, which further complicates the process of accessing relevant data by using search queries. Search over encrypted data schemes solve this problem by exploiting cryptographic primitives and secure indexing to identify outsourced data that satisfy the search criteria. Almost all of these schemes rely on exact matching between the encrypted data and search criteria. A few schemes which extend the notion of exact matching to similarity based search, lack realism as those schemes rely on trusted third parties or due to increase storage and computational complexity. In this paper we propose Oblivious Similarity based Search (OS2) for encrypted data. It enables authorized users to model their own encrypted search queries which are resilient to typographical errors. Unlike conventional methodologies, OS2 ranks the search results by using similarity measure offering a better search experience than exact matching. It utilizes encrypted bloom filter and probabilistic homomorphic encryption to enable authorized users to access relevant data without revealing results of search query evaluation process to the untrusted cloud service provider. Encrypted bloom filter based search enables OS2 to reduce search space to potentially relevant encrypted data avoiding unnecessary computation on public cloud. The efficacy of OS2 is evaluated on Google App Engine for various bloom filter lengths on different cloud configurations. PMID:28692697

  14. Improving Web image search by bag-based reranking.

    PubMed

    Duan, Lixin; Li, Wen; Tsang, Ivor Wai-Hung; Xu, Dong

    2011-11-01

    Given a textual query in traditional text-based image retrieval (TBIR), relevant images are to be reranked using visual features after the initial text-based search. In this paper, we propose a new bag-based reranking framework for large-scale TBIR. Specifically, we first cluster relevant images using both textual and visual features. By treating each cluster as a "bag" and the images in the bag as "instances," we formulate this problem as a multi-instance (MI) learning problem. MI learning methods such as mi-SVM can be readily incorporated into our bag-based reranking framework. Observing that at least a certain portion of a positive bag is of positive instances while a negative bag might also contain positive instances, we further use a more suitable generalized MI (GMI) setting for this application. To address the ambiguities on the instance labels in the positive and negative bags under this GMI setting, we develop a new method referred to as GMI-SVM to enhance retrieval performance by propagating the labels from the bag level to the instance level. To acquire bag annotations for (G)MI learning, we propose a bag ranking method to rank all the bags according to the defined bag ranking score. The top ranked bags are used as pseudopositive training bags, while pseudonegative training bags can be obtained by randomly sampling a few irrelevant images that are not associated with the textual query. Comprehensive experiments on the challenging real-world data set NUS-WIDE demonstrate our framework with automatic bag annotation can achieve the best performances compared with existing image reranking methods. Our experiments also demonstrate that GMI-SVM can achieve better performances when using the manually labeled training bags obtained from relevance feedback.

  15. A Full-Text-Based Search Engine for Finding Highly Matched Documents Across Multiple Categories

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung D.; Steele, Gynelle C.

    2016-01-01

    This report demonstrates the full-text-based search engine that works on any Web-based mobile application. The engine has the capability to search databases across multiple categories based on a user's queries and identify the most relevant or similar. The search results presented here were found using an Android (Google Co.) mobile device; however, it is also compatible with other mobile phones.

  16. Publishers' Note

    NASA Astrophysics Data System (ADS)

    EPL Management Team

    2008-12-01

    We would like to thank all our contributors, subscribers, reviewers, and readers for their interest in EPL during 2008. You each play an invaluable role in the promotion, prestige, development and success of the journal and therefore your continued support is greatly appreciated. The Directors' vision for EPL to become a leading home for global physics letters, to offer rapid publication of ground-breaking physics results from the international community, and to provide the broadest coverage of physics research, is beginning to take shape as increased submissions, reduced acceptance rates, raised scientific quality, rapid publication, and greater visibility amongst the community are achieved. The latest published articles will continue to be freely available for 30 days from their on-line publication. Those articles highlighted by the Co-Editors in 2008 will remain free-to-all for the entire of 2009. We invite you to visit the website regularly (http://www.epljournal.org) to stay up-to-date with the journal's latest developments and to read the most recent articles. Our most recent opportunity publicized on the EPL website and in the CERN SCOAP3 (Sponsoring Consortium for Open Access Publishing in Particle Physics) messages is below: Open Access Opportunity for Authors of Experimental and Theoretical HEP Articles EPL is delighted to offer open access free of charge to all authors submitting experimental and theoretical letters in PACS codes 10 and 20. This offer will remain open until the SCOAP3 agreement at CERN takes effect. Authors submitting any article to EPL will continue to be offered the opportunity to make their published letter open access for a one-off payment. However, with effect from 1 November 2008, any author who submits work related to subject areas within PACS 10 and 20 will benefit from open access at no charge, meaning their published article will be available free to all readers, forever. ``Physics of Elementary Particles and Fields'' and

  17. Effectiveness of Interactive Computer-Based Instruction: A Review of Studies Published between 1995 and 2007

    ERIC Educational Resources Information Center

    Johnson, Douglas A.; Rubin, Sophie

    2011-01-01

    Computer-based instruction (CBI) has been growing rapidly as a training tool in organizational settings, but close attention to behavioral factors has often been neglected. CBI represents a promising instructional advancement over current training methods. This review article summarizes 12 years of comparative research in interactive…

  18. Publishing for Mother Tongue-Based Bilingual Education in Ghana: Politics and Consequences

    ERIC Educational Resources Information Center

    Opoku-Amankwa, Kwasi; Edu-Buandoh, Dora F.; Brew-Hammond, Aba

    2015-01-01

    One often cited challenge to effective mother tongue-based bilingual education (MTBE) in multilingual countries like Ghana is the difficulty of developing curriculum and instructional materials in many languages. To explain this situation, factors such as shortage of writers and teachers in the local languages, lack of interest on the part of…

  19. Publishing for Mother Tongue-Based Bilingual Education in Ghana: Politics and Consequences

    ERIC Educational Resources Information Center

    Opoku-Amankwa, Kwasi; Edu-Buandoh, Dora F.; Brew-Hammond, Aba

    2015-01-01

    One often cited challenge to effective mother tongue-based bilingual education (MTBE) in multilingual countries like Ghana is the difficulty of developing curriculum and instructional materials in many languages. To explain this situation, factors such as shortage of writers and teachers in the local languages, lack of interest on the part of…

  20. Publisher's Announcement

    NASA Astrophysics Data System (ADS)

    Scriven, Neil

    2003-12-01

    We are delighted to announce that the new Editor-in-Chief of Journal of Physics A: Mathematical and General for 2004 will be Professor Carl M Bender of Washington University, St. Louis. Carl will, with the help of his world class editorial board, maintain standards of scientific rigour whilst ensuring that research published is of the highest importance. Carl attained his first degree in physics at Cornell University before studying for his PhD at Harvard. He later worked at The Institute for Advanced Study in Princeton and at MIT before assuming his current position at Washington University, St Louis. He has been a visiting professor at Technion, Haifa, and Imperial College, London and a scientific consultant for Los Alamos National Laboratory. His main expertise is in using classical applied mathematics to solve a broad range of problems in high-energy theoretical physics and mathematical physics. Since the publication of his book Advanced Mathematical Methods for Scientists and Engineers, written with Steven Orszag, he has been regarded as an expert on the subject of asymptotic analysis and perturbative methods. `Carl publishes his own internationally-important research in the journal and has been an invaluable, energetic member of the Editorial Board for some time' said Professor Ed Corrigan, Carl's predecessor as Editor, `he will be an excellent Editor-in-Chief'. Our grateful thanks and best wishes go to Professor Corrigan who has done a magnificent job for the journal during his five-year tenure.

  1. Publisher's Announcement

    NASA Astrophysics Data System (ADS)

    McGlashan, Yasmin

    2008-01-01

    Important changes for 2008 As a result of reviewing several aspects of our content, both in print and online, we have made some changes for 2008. These changes are described below: Article numbering Plasma Physics and Controlled Fusion has moved from sequential page numbering to an article numbering system, offering important advantages and flexibility by speeding up the publication process. Papers in different issues or sections can be published online as soon as they are ready, without having to wait for a whole issue or section to be allocated page numbers. The bibliographic citation will change slightly. Articles should be referenced using the six-digit article number in place of a page number, and this number must include any leading zeros. For instance, from this issue: Z Y Chen et al 2008 Plasma Phys. Control. Fusion 50 015001 Articles will continue to be published on the web in advance of the print edition. A new look and feel We have also taken the opportunity to refresh the design of the journal cover, in order to modernise the typography and create a consistent look and feel across our range of publications. We hope you like the new cover. If you have any questions or comments about any of these changes, please contact us at ppcf@iop.org.

  2. Numerical database system based on a weighted search tree

    NASA Astrophysics Data System (ADS)

    Park, S. C.; Bahri, C.; Draayer, J. P.; Zheng, S.-Q.

    1994-09-01

    An on-line numerical database system, that is based on the concept of a weighted search tree and which functions like a file directory, is introduced. The system, which is designed to aid in reducing time-consuming redundant calculations in numerically intensive computations, can be used to fetch, insert and delete items from a dynamically generated list in optimal [ O(log n) where n is the number of items in the list] time. Items in the list are ordered according to a priority queue with the initial priority for each element set either automatically or by an user supplied algorithm. The priority queue is updated on-the-fly to reflect element hit frequency. Items can be added to a database so long as there is space to accommodate them, and when there is not, the lowest priority element(s) is removed to make room for an incoming element(s) with higher priority. The system acts passively and therefore can be applied to any number of databases, with the same or different structures, within a single application.

  3. A "Tuned" Mask Learnt Approach Based on Gravitational Search Algorithm.

    PubMed

    Wan, Youchuan; Wang, Mingwei; Ye, Zhiwei; Lai, Xudong

    2016-01-01

    Texture image classification is an important topic in many applications in machine vision and image analysis. Texture feature extracted from the original texture image by using "Tuned" mask is one of the simplest and most effective methods. However, hill climbing based training methods could not acquire the satisfying mask at a time; on the other hand, some commonly used evolutionary algorithms like genetic algorithm (GA) and particle swarm optimization (PSO) easily fall into the local optimum. A novel approach for texture image classification exemplified with recognition of residential area is detailed in the paper. In the proposed approach, "Tuned" mask is viewed as a constrained optimization problem and the optimal "Tuned" mask is acquired by maximizing the texture energy via a newly proposed gravitational search algorithm (GSA). The optimal "Tuned" mask is achieved through the convergence of GSA. The proposed approach has been, respectively, tested on some public texture and remote sensing images. The results are then compared with that of GA, PSO, honey-bee mating optimization (HBMO), and artificial immune algorithm (AIA). Moreover, feature extracted by Gabor wavelet is also utilized to make a further comparison. Experimental results show that the proposed method is robust and adaptive and exhibits better performance than other methods involved in the paper in terms of fitness value and classification accuracy.

  4. Evaluating Search Engine Relevance with Click-Based Metrics

    NASA Astrophysics Data System (ADS)

    Radlinski, Filip; Kurup, Madhu; Joachims, Thorsten

    Automatically judging the quality of retrieval functions based on observable user behavior holds promise for making retrieval evaluation faster, cheaper, and more user centered. However, the relationship between observable user behavior and retrieval quality is not yet fully understood. In this chapter, we expand upon, Radlinski et al. (How does clickthrough data reflect retrieval quality, In Proceedings of the ACM Conference on Information and Knowledge Management (CIKM), 43-52, 2008), presenting a sequence of studies investigating this relationship for an operational search engine on the arXiv.org e-print archive. We find that none of the eight absolute usage metrics we explore (including the number of clicks observed, the frequency with which users reformulate their queries, and how often result sets are abandoned) reliably reflect retrieval quality for the sample sizes we consider. However, we find that paired experiment designs adapted from sensory analysis produce accurate and reliable statements about the relative quality of two retrieval functions. In particular, we investigate two paired comparison tests that analyze clickthrough data from an interleaved presentation of ranking pairs, and find that both give accurate and consistent results. We conclude that both paired comparison tests give substantially more accurate and sensitive evaluation results than the absolute usage metrics in our domain.

  5. Particle Swarm Based Collective Searching Model for Adaptive Environment

    SciTech Connect

    Cui, Xiaohui; Patton, Robert M; Potok, Thomas E; Treadwell, Jim N

    2008-01-01

    This report presents a pilot study of an integration of particle swarm algorithm, social knowledge adaptation and multi-agent approaches for modeling the collective search behavior of self-organized groups in an adaptive environment. The objective of this research is to apply the particle swarm metaphor as a model of social group adaptation for the dynamic environment and to provide insight and understanding of social group knowledge discovering and strategic searching. A new adaptive environment model, which dynamically reacts to the group collective searching behaviors, is proposed in this research. The simulations in the research indicate that effective communication between groups is not the necessary requirement for whole self-organized groups to achieve the efficient collective searching behavior in the adaptive environment.

  6. Particle Swarm Based Collective Searching Model for Adaptive Environment

    SciTech Connect

    Cui, Xiaohui; Patton, Robert M; Potok, Thomas E; Treadwell, Jim N

    2007-01-01

    This report presents a pilot study of an integration of particle swarm algorithm, social knowledge adaptation and multi-agent approaches for modeling the collective search behavior of self-organized groups in an adaptive environment. The objective of this research is to apply the particle swarm metaphor as a model of social group adaptation for the dynamic environment and to provide insight and understanding of social group knowledge discovering and strategic searching. A new adaptive environment model, which dynamically reacts to the group collective searching behaviors, is proposed in this research. The simulations in the research indicate that effective communication between groups is not the necessary requirement for whole self-organized groups to achieve the efficient collective searching behavior in the adaptive environment.

  7. Risk-based scheduling of multiple search passes for UUVs

    NASA Astrophysics Data System (ADS)

    Baylog, John G.; Wettergren, Thomas A.

    2016-05-01

    This paper addresses selected computational aspects of collaborative search planning when multiple search agents seek to find hidden objects (i.e. mines) in operating environments where the detection process is prone to false alarms. A Receiver Operator Characteristic (ROC) analysis is applied to construct a Bayesian cost objective function that weighs and combines missed detection and false alarm probabilities. It is shown that for fixed ROC operating points and a validation criterion consisting of a prerequisite number of detection outcomes, an interval exists in the number of conducted search passes over which the risk objective function is supermodular. We show that this property is not retained beyond validation criterion boundaries. We investigate the use of greedy algorithms for distributing search effort and, in particular, examine the double greedy algorithm for its applicability under conditions of varying criteria. Numerical results are provided to demonstrate the effectiveness of the approach.

  8. Computer Search Center Statistics on Users and Data Bases

    ERIC Educational Resources Information Center

    Schipma, Peter B.

    1974-01-01

    Statistics gathered over five years of operation by the IIT Research Institute's Computer Search Center are summarized for profile terms and lists, use of truncation modes, use of logic operators, some characteristics of CA Condensates, etc. (Author/JB)

  9. Entity-based Stochastic Analysis of Search Results for Query Expansion and Results Re-Ranking

    DTIC Science & Technology

    2015-11-20

    based on named-entity recognition applied in a set of search re- sults, and on a graph of documents and identified entities that is constructed...dynamically a graph of documents and entities, and then to analyze it stochastically using a Random Walk- based method. Specifically, we model the search...process as a random walker of the graph defined by the top documents returned by a search system and the entities identified in these documents. For

  10. The U.S. Online News Coverage of Mammography Based on a Google News Search.

    PubMed

    Young Lin, Leng Leng; Rosenkrantz, Andrew B

    2017-07-07

    To characterize online news coverage relating to mammography, including articles' stance toward screening mammography. Google News was used to search U.S. news sites over a 9-year period (2006-2015) based on the search terms "mammography" and "mammogram." The top 100 search results were recorded. Identified articles were manually reviewed. The top 100 news articles were from the following sources: local news outlet (50%), national news outlet (24%), nonimaging medical source (13%), entertainment or culture news outlet (6%), business news outlet (4%), peer-reviewed journal (1%), and radiology news outlet (1%). Most common major themes were the screening mammography controversy (29%), description of a new breast imaging technology (23%), dense breasts (11%), and promotion of a public screening initiative (11%). For the most recent year, article stance toward screening mammography was 59%, favorable; 16%, unfavorable; and 25%, neutral. After 2010, there was an abrupt shift in articles' stances from neutral to both favorable and unfavorable. A wide range of online news sources addressed a range of issues related to mammography. National, rather than local, news sites were more likely to focus on the screening controversy and more likely to take an unfavorable view. The controversial United States Preventive Services Task Force guidelines may have influenced articles to take a stance on screening mammography. As such online news may impact public perception of the topic and thus potentially impact guideline adherence, radiologists are encouraged to maintain awareness of this online coverage and to support the online dissemination of reliable and accurate information. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  11. CoPub Mapper: mining MEDLINE based on search term co-publication

    PubMed Central

    Alako, Blaise TF; Veldhoven, Antoine; van Baal, Sjozef; Jelier, Rob; Verhoeven, Stefan; Rullmann, Ton; Polman, Jan; Jenster, Guido

    2005-01-01

    Background High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In order to identify biological similarities between genes, publications from MEDLINE were identified in which pairs of gene names and combinations of gene name with specific keywords were co-mentioned. Results MEDLINE search strings for 15,621 known genes and 3,731 keywords were generated and validated. PubMed IDs were retrieved from MEDLINE and relative probability of co-occurrences of all gene-gene and gene-keyword pairs determined. To assess gene clustering according to literature co-publication, 150 genes consisting of 8 sets with known connections (same pathway, same protein complex, or same cellular localization, etc.) were run through the program. Receiver operator characteristics (ROC) analyses showed that most gene sets were clustered much better than expected by random chance. To test grouping of genes from real microarray data, 221 differentially expressed genes from a microarray experiment were analyzed with CoPub Mapper, which resulted in several relevant clusters of genes with biological process and disease keywords. In addition, all genes versus keywords were hierarchical clustered to reveal a complete grouping of published genes based on co-occurrence. Conclusion The CoPub Mapper program allows for quick and versatile querying of co-published genes and keywords and can be successfully used to cluster predefined groups of genes and microarray data. PMID:15760478

  12. Demeter, persephone, and the search for emergence in agent-based models.

    SciTech Connect

    North, M. J.; Howe, T. R.; Collier, N. T.; Vos, J. R.; Decision and Information Sciences; Univ. of Chicago; PantaRei Corp.; Univ. of Illinois

    2006-01-01

    In Greek mythology, the earth goddess Demeter was unable to find her daughter Persephone after Persephone was abducted by Hades, the god of the underworld. Demeter is said to have embarked on a long and frustrating, but ultimately successful, search to find her daughter. Unfortunately, long and frustrating searches are not confined to Greek mythology. In modern times, agent-based modelers often face similar troubles when searching for agents that are to be to be connected to one another and when seeking appropriate target agents while defining agent behaviors. The result is a 'search for emergence' in that many emergent or potentially emergent behaviors in agent-based models of complex adaptive systems either implicitly or explicitly require search functions. This paper considers a new nested querying approach to simplifying such agent-based modeling and multi-agent simulation search problems.

  13. Neural integration of top-down spatial and feature-based information in visual search.

    PubMed

    Egner, Tobias; Monti, Jim M P; Trittschuh, Emily H; Wieneke, Christina A; Hirsch, Joy; Mesulam, M-Marsel

    2008-06-11

    Visual search is aided by previous knowledge regarding distinguishing features and probable locations of a sought-after target. However, how the human brain represents and integrates concurrent feature-based and spatial expectancies to guide visual search is currently not well understood. Specifically, it is not clear whether spatial and feature-based search information is initially represented in anatomically segregated regions, nor at which level of processing expectancies regarding target features and locations may be integrated. To address these questions, we independently and parametrically varied the degree of spatial and feature-based (color) cue information concerning the identity of an upcoming visual search target while recording blood oxygenation level-dependent (BOLD) responses in human subjects. Search performance improved with the amount of spatial and feature-based cue information, and cue-related BOLD responses showed that, during preparation for visual search, spatial and feature cue information were represented additively in shared frontal, parietal, and cingulate regions. These data show that representations of spatial and feature-based search information are integrated in source regions of top-down biasing and oculomotor planning before search onset. The purpose of this anticipatory integration could lie with the generation of a "top-down salience map," a search template of primed target locations and features. Our results show that this role may be served by the intraparietal sulcus, which additively integrated a spatially specific activation gain in relation to spatial cue information with a spatially global activation gain in relation to feature cue information.

  14. Contrasting Gist-Based and Template-Based Guidance During Real-World Visual Search.

    PubMed

    Bahle, Brett; Matsukura, Michi; Hollingworth, Andrew

    2017-08-10

    Visual search through real-world scenes is guided both by a representation of target features and by knowledge of the sematic properties of the scene (derived from scene gist recognition). In 3 experiments, we compared the relative roles of these 2 sources of guidance. Participants searched for a target object in the presence of a critical distractor object. The color of the critical distractor either matched or mismatched (a) the color of an item maintained in visual working memory for a secondary task (Experiment 1), or (b) the color of the target, cued by a picture before search commenced (Experiments 2 and 3). Capture of gaze by a matching distractor served as an index of template guidance. There were 4 main findings: (a) The distractor match effect was observed from the first saccade on the scene, (b) it was independent of the availability of scene-level gist-based guidance, (c) it was independent of whether the distractor appeared in a plausible location for the target, and (d) it was preserved even when gist-based guidance was available before scene onset. Moreover, gist-based, semantic guidance of gaze to target-plausible regions of the scene was delayed relative to template-based guidance. These results suggest that feature-based template guidance is not limited to plausible scene regions after an initial, scene-level analysis. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  15. Evidence-based dentistry: Part II. Searching for answers to clinical questions: how to use MEDLINE.

    PubMed

    Sutherland, S E

    2001-05-01

    The ability to conduct efficient literature searches is fundamental to the practice of evidence-based dentistry. In the second part of this series on evidence-based dentistry, strategic literature search techniques are discussed. MEDLINE, because of its breadth, depth and continuous maintenance by the U.S. National Library of Medicine (NLM), is the best source of evidence for health care. Although there are many gateways to MEDLINE, this paper highlights the user-friendly versions of MEDLINE offered free on the Internet by the NLM. The use of well-established search tactics and the unique features of the NLM sites facilitate rapid, effective literature searches.

  16. Publishing in the Next Few Years: A Commercial Publisher's Perspective

    NASA Astrophysics Data System (ADS)

    Blom, Harry J. J.

    Over the past 15 years, internet technology changed the ways of publishing tremendously. It is truly revolutionary that both fresh and historic science publications are so much easier to search and find. This revolution has not been completed and all parties involved in science publishing are continuously adjusting their activities to the new rules and opportunities. From a commercial publisher's perspective, I will extrapolate what happens today to predict what happens in the next few years with journal subscriptions, book publishing, marketing, production and other steps in the publishing process.

  17. Genetic engineering: Baculoviruses as expression vectors. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the use of baculoviruses in genetic engineering. Baculoviruses produce large quantities of a specific gene. Topics include genetic replication, expression of selected genes in host cells, and protein expression using baculoviruses. Baculovirus introduction into mammals causing antibody expression is considered, and implications on vaccine programs are briefly discussed. (Contains a minimum of 112 citations and includes a subject term index and title list.)

  18. Heavy metals in drinking water: Standards, sources, and effects. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning the public health aspects and documented studies of heavy metal pollutants in drinking water. Topics include human exposure studies and the toxicological effects incurred by ingestion. Prolonged exposure and quantification factors and effects, federal and state regulations and standards, and laboratory animal studies are discussed. Among the pollution pathways examined are landfill contamination of groundwater, acid precipitation contributions to groundwater pollution, and corrosion by-products in residential plumbing and public water supply transport systems. (Contains a minimum of 105 citations and includes a subject term index and title list.)

  19. Sulfur dioxide control: Sulfur dioxide from coal-burning sources. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning air pollution control technology and various methods for desulfurization of coal combustion streams. Examples include fluidized bed and other combustion modifications, and the removal of sulfur dioxide from flue gas. Proper monitoring of the effluent to meet the established atmospheric standards is also discussed. Applications in powerplants, steam boilers, furnaces, kilns, and gas turbines are presented. (Contains 250 citations and includes a subject term index and title list.)

  20. Aquatic plants: Ecology and environment. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning growth and ecology of aquatic flora in lakes, rivers, and coastal areas. Effects of domestic sewage, industrial wastes, and oil spills on aquatic ecosystems are discussed. Algal population growth in rivers and polluted areas is considered, and use of benthic algae as biological indicators of water quality is also discussed. (Contains a minimum of 86 citations and includes a subject term index and title list.)

  1. Chernobyl nuclear reactor accident fallout: measurement and consequences. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the consequences of radioactive fallout from the Chernobyl nuclear reactor accident. Coverage includes transfrontier radioactive contamination, deposition of radioactive pollutants from the atmosphere, and radionuclide concentrations in ground-level air and soil contamination, and in vegetation and food. Monthly radioactive monitoring in different countries, possible health hazards caused by the radiation, and estimates of radiation doses to the population from the fallout are also discussed. (Contains a minimum of 209 citations and includes a subject term index and title list.)

  2. Asbestos: Industrial applications and precautions. (Latest citations from Information Services in Mechanical Engineering data base). Published Search

    SciTech Connect

    Not Available

    1992-07-01

    The bibliography contains citations concerning the properties, industrial uses and federal regulation of asbestos. The references explore advantages and disadvantages associated with use of industrial robots in areas containing high concentrations of asbestos dust, the use of water as a cutting tool to control the generation of asbestos dust, and governmental policies and attitudes relative to the health and welfare of workers subjected to asbestos. Thermal insulation properties, wear characteristics, high temperature capabilities, use as a reinforcement in composite materials, and asbestos substitutes are included. (Contains a minimum of 69 citations and includes a subject term index and title list.)

  3. Comfort and human factors in office and residential settings. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning human factors engineering, anthropometry, and ergonomics as they relate to human comfort in the office and home. Human requirements, including ventilation, temperature control, and lighting, are considered. Research regarding environmental architecture, and engineering, safety, and convenience aspects are discussed. (Contains a minimum of 142 citations and includes a subject term index and title list.)

  4. Pesticide toxicity in aquatic environments. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning determination, research, causes, effects, and control of pesticide toxicity in aquatic environments. Bioaccumulation of toxic substances and assay methods to determine their effects are considered. Synergistic effects of combinations of chemical agents are also considered. (Contains 250 citations and includes a subject term index and title list.)

  5. Biological effects and environmental fate of antifouling substances. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the environmental effects and eventual fate of antifouling substances used to control biofouling. Topics include toxicity studies, the effects of regulations on pollution distribution, bioaccumulation and sediment accumulation, resistant organisms, and biodeterioration of antifouling substances. Antifouling materials considered include copper, nickel, and organotin compounds. Marine fouling, cooling system fouling, and antifouling paints are discussed in separate bibliographies. (Contains 250 citations and includes a subject term index and title list.)

  6. Sulfur dioxide control (excludes coal-burning sources). (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning air pollution control technology and removal of sulfur dioxide from waste streams and atmospheres. Removal methods include flue gas desulfurization by wet or dry sorbents, electron beam processes, corona discharge, reductive gases, microbial processes, and burner injection systems. Applications to utilities, oil refineries, and the metallurgical and chemical industries are described. Control of sulfur dioxide produced from coal burning is discussed in a separate bibliography. (Contains 250 citations and includes a subject term index and title list.)

  7. Oil spill removal: Dispersants, absorbents, booms, and skimmers. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the techniques available for the removal of oil following major spills. Chemical dispersants, gelling agents, foam plastics, booms, skimmers, and burning are discussed. Specific oil spills are considered and the environmental impacts of oil spills are noted. (Contains a minimum of 207 citations and includes a subject term index and title list.)

  8. Waste disposal and treatment in the food-processing industry. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-08-01

    The bibliography contains citations concerning waste treatment and disposal in the food processing industry. Methods, equipment, and technology are considered. Specific areas include waste heat recovery, and food industry wastes from meat and seafood processing, dairy and beverage production, and processing of fruits and vegetables. The citations explore conversion of the treated waste to fertilizer, and uses in animal feeds, combustion for energy production, biogas production, and composting. The recovery and recycling of usable chemicals from the food waste is also covered. Food packaging recycling is considered in a related bibliography. (Contains 250 citations and includes a subject term index and title list.)

  9. Waste water treatment by sand filtration. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the use of sand filtration in the treatment of wastewaters. Treatment systems for both domestic and industrial effluents are discussed. Designs, processes, applications and performance evaluations of sand filters, columns, and mounds used as primary filtering mechanisms are included. (Contains a minimum of 227 citations and includes a subject term index and title list.)

  10. Bioaccumulation of heavy metals by fish. (Latest citations from the Selected Water Resources Abstracts data base). Published Search

    SciTech Connect

    Not Available

    1992-06-01

    The bibliography contains citations concerning the global distribution and bioaccumulation of heavy metals in marine and freshwater fish. Surveys, toxicological effects, mechanisms of accumulation, and temperature-concentration effects are discussed. (Contains 250 citations and includes a subject term index and title list.)

  11. Technology transfer in the life sciences. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning technology transfer in the life sciences. Topics include technology transfer in biogas energy production, biotechnology, pollution control, aquaculture, agriculture, oceanography, and forestry. Technology transfer to developing countries and to small businesses, as well as university-industry partnerships, is described. (Contains a minimum of 71 citations and includes a subject term index and title list.)

  12. Sediment-water interactions and their effects upon water quality. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the transport and fate of contaminants in freshwater systems containing sediments. Topics include nutrient recycling, absorption and desorption of a variety of contaminants, ion exchange processes, and the use of transport models in contamination studies. Citations pertaining specifically to marine environments are excluded. (Contains 250 citations and includes a subject term index and title list.)

  13. Biological effects of electrical- or magnetic-field application. (Latest citations from the Life Sciences Collection data base). Published Search

    SciTech Connect

    Not Available

    1992-09-01

    The bibliography contains citations concerning the application of electrical or magnetic fields to organisms. Changes in cell structure, cell shape, metabolism, mitosis, cell orientation, neuron response, germination response, and growth rates are discussed. The citations also examine the effects of electrical or magnetic field exposure from transmission lines. Biological applications of electric field cited include genetic transfer, plant cell fusion, and seed disinfection. (Contains 250 citations and includes a subject term index and title list.)

  14. Genetic engineering of plants for improved crop production. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning the use of genetic engineering to improve crop production. Genetic alterations of plants to provide insect protection, herbicide resistance, disease resistance, improved quality, and higher yield are discussed. Methods used to develop environmentally tolerant crops that are able to withstand extremes of temperature, reduced water consumption, and reduced fertilizer requirements are examined. Genetic engineering of microorganisms that are beneficial to plants is discussed in a separate bibliography. (Contains 250 citations and includes a subject term index and title list.)

  15. Remote sensing applied to environmental-pollution detection and management. (Latest citations from the NTIS data base). Published Search

    SciTech Connect

    Not Available

    1992-04-01

    The bibliography contains citations concerning the utilization of remote sensing techniques and equipment to study air and water pollution. Topics include the use of aerial photographs, radar, and spaceborne photography to study oil spills, ocean dumping sites, plume dispersions, and pollution problems in estuaries. Data interpretation and processing techniques are also discussed. (Contains 250 citations and includes a subject term index and title list.)

  16. Pollution-liability insurance: Availability, demand, and coverage. (Latest citations from the Biobusiness data base). Published Search

    SciTech Connect

    Not Available

    1992-05-01

    The bibliography contains citations concerning pollution liability insurance availability, demand, and coverage. References discuss the reduced availability of pollution liability insurance, the increased demand for this insurance, and the impact of Superfund decisions by the US Environmental Protection Agency (EPA) on pollution liability insurance claims. Court cases to determine whether the polluting company or the insurance company is responsible for hazardous materials cleanup are cited. Requirements for self insurance and elimination of the requirement for hazardous waste clean-up companies to be insured by a third company are included. (Contains a minimum of 204 citations and includes a subject term index and title list.)

  17. Effects of Discipline-based Career Course on Nursing Students' Career Search Self-efficacy, Career Preparation Behavior, and Perceptions of Career Barriers.

    PubMed

    Park, Soonjoo

    2015-09-01

    The purpose of this study was to investigate the effectiveness of a discipline-based career course on perceptions of career barriers, career search self-efficacy, and career preparation behavior of nursing students. Differences in career search self-efficacy and career preparation behavior by the students' levels of career barriers were also examined. The study used a modified one-group, pretest-posttest design. The convenience sample consisted of 154 undergraduate nursing students in a university. The discipline-based career course consisted of eight sessions, and was implemented for 2 hours per session over 8 weeks. The data were collected from May to June in 2012 and 2013 using the following instruments: the Korean Career Indecision Inventory, the Career Search Efficacy Scale, and the Career Preparation Behavior Scale. Descriptive statistics, paired t test, and analysis of covariance were used to analyze the data. Upon the completion of the discipline-based career course, students' perceptions of career barriers decreased and career search self-efficacy and career preparation behavior increased. Career search self-efficacy and career preparation behavior increased in students with both low and high levels of career barriers. The difference between the low and high groups was significant for career search self-efficacy but not for career preparation behavior. The discipline-based career course was effective in decreasing perceptions of career barriers and increasing career search self-efficacy and career preparation behavior among nursing students. Copyright © 2015. Published by Elsevier B.V.

  18. Lights, Camera, Publishing?

    ERIC Educational Resources Information Center

    Ayoub, Nina C.

    2008-01-01

    Are university presses ready for their close-up? In a nod to Hollywood, a growing number of trade publishers are producing book trailers to promote new titles. But do video teasers have a role in university-press publishing? What about longer formats? Based on an entirely unscientific poll of publicists at 25 university presses, the answer appears…

  19. Lights, Camera, Publishing?

    ERIC Educational Resources Information Center

    Ayoub, Nina C.

    2008-01-01

    Are university presses ready for their close-up? In a nod to Hollywood, a growing number of trade publishers are producing book trailers to promote new titles. But do video teasers have a role in university-press publishing? What about longer formats? Based on an entirely unscientific poll of publicists at 25 university presses, the answer appears…

  20. Effectiveness of school-based interventions in Europe to promote healthy nutrition in children and adolescents: systematic review of published and 'grey' literature.

    PubMed

    Van Cauwenberghe, Eveline; Maes, Lea; Spittaels, Heleen; van Lenthe, Frank J; Brug, Johannes; Oppert, Jean-Michel; De Bourdeaudhuij, Ilse

    2010-03-01

    The objective of the present review was to summarise the existing European published and 'grey' literature on the effectiveness of school-based interventions to promote a healthy diet in children (6-12 years old) and adolescents (13-18 years old). Eight electronic databases, websites and contents of key journals were systematically searched, reference lists were screened, and authors and experts in the field were contacted for studies evaluating school-based interventions promoting a healthy diet and aiming at primary prevention of obesity. The studies were included if they were published between 1 January 1990 and 31 December 2007 and reported effects on dietary behaviour or on anthropometrics. Finally, forty-two studies met the inclusion criteria: twenty-nine in children and thirteen in adolescents. In children, strong evidence of effect was found for multicomponent interventions on fruit and vegetable intakes. Limited evidence of effect was found for educational interventions on behaviour, and for environmental interventions on fruit and vegetable intakes. Interventions that specifically targeted children from lower socio-economic status groups showed limited evidence of effect on behaviour. In adolescents, moderate evidence of effect was found for educational interventions on behaviour and limited evidence of effect for multicomponent programmes on behaviour. In children and adolescents, effects on anthropometrics were often not measured, and therefore evidence was lacking or delivered inconclusive evidence. To conclude, evidence was found for the effectiveness of especially multicomponent interventions promoting a healthy diet in school-aged children in European Union countries on self-reported dietary behaviour. Evidence for effectiveness on anthropometrical obesity-related measures is lacking.

  1. Development of a Search Strategy for an Evidence Based Retrieval Service

    PubMed Central

    Ho, Gah Juan; Liew, Su May; Ng, Chirk Jenn; Hisham Shunmugam, Ranita; Glasziou, Paul

    2016-01-01

    Background Physicians are often encouraged to locate answers for their clinical queries via an evidence-based literature search approach. The methods used are often not clearly specified. Inappropriate search strategies, time constraint and contradictory information complicate evidence retrieval. Aims Our study aimed to develop a search strategy to answer clinical queries among physicians in a primary care setting Methods Six clinical questions of different medical conditions seen in primary care were formulated. A series of experimental searches to answer each question was conducted on 3 commonly advocated medical databases. We compared search results from a PICO (patients, intervention, comparison, outcome) framework for questions using different combinations of PICO elements. We also compared outcomes from doing searches using text words, Medical Subject Headings (MeSH), or a combination of both. All searches were documented using screenshots and saved search strategies. Results Answers to all 6 questions using the PICO framework were found. A higher number of systematic reviews were obtained using a 2 PICO element search compared to a 4 element search. A more optimal choice of search is a combination of both text words and MeSH terms. Despite searching using the Systematic Review filter, many non-systematic reviews or narrative reviews were found in PubMed. There was poor overlap between outcomes of searches using different databases. The duration of search and screening for the 6 questions ranged from 1 to 4 hours. Conclusion This strategy has been shown to be feasible and can provide evidence to doctors’ clinical questions. It has the potential to be incorporated into an interventional study to determine the impact of an online evidence retrieval system. PMID:27935993

  2. Semi-supervised weighted kernel clustering based on gravitational search for fault diagnosis.

    PubMed

    Li, Chaoshun; Zhou, Jianzhong

    2014-09-01

    Supervised learning method, like support vector machine (SVM), has been widely applied in diagnosing known faults, however this kind of method fails to work correctly when new or unknown fault occurs. Traditional unsupervised kernel clustering can be used for unknown fault diagnosis, but it could not make use of the historical classification information to improve diagnosis accuracy. In this paper, a semi-supervised kernel clustering model is designed to diagnose known and unknown faults. At first, a novel semi-supervised weighted kernel clustering algorithm based on gravitational search (SWKC-GS) is proposed for clustering of dataset composed of labeled and unlabeled fault samples. The clustering model of SWKC-GS is defined based on wrong classification rate of labeled samples and fuzzy clustering index on the whole dataset. Gravitational search algorithm (GSA) is used to solve the clustering model, while centers of clusters, feature weights and parameter of kernel function are selected as optimization variables. And then, new fault samples are identified and diagnosed by calculating the weighted kernel distance between them and the fault cluster centers. If the fault samples are unknown, they will be added in historical dataset and the SWKC-GS is used to partition the mixed dataset and update the clustering results for diagnosing new fault. In experiments, the proposed method has been applied in fault diagnosis for rotatory bearing, while SWKC-GS has been compared not only with traditional clustering methods, but also with SVM and neural network, for known fault diagnosis. In addition, the proposed method has also been applied in unknown fault diagnosis. The results have shown effectiveness of the proposed method in achieving expected diagnosis accuracy for both known and unknown faults of rotatory bearing. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  3. Variable Neighborhood Search Coupled with ILP-Based Very Large Neighborhood Searches for the (Periodic) Location-Routing Problem

    NASA Astrophysics Data System (ADS)

    Pirkwieser, Sandro; Raidl, Günther R.

    This work deals with the application of a variable neighborhood search (VNS) to the capacitated location-routing problem (LRP) as well as to the more general periodic LRP (PLRP). For this, previous successful VNS algorithms for related problems are considered and accordingly adapted as well as extended. The VNS is subsequently combined with three very large neighborhood searches (VLNS) based on integer linear programming: Two operate on whole routes and do a rather coarse, yet powerful optimization, with the more sophisticated one also taking the single customers into account, and the third operates on customer sequences to do a more fine-grained optimization. Several VNS plus VLNS combinations are presented and very encouraging experimental results are given. Our method clearly outperforms previous PLRP approaches and is at least competitive to leading approaches for the LRP.

  4. Cost analysis of screening for, diagnosing, and staging prostate cancer based on a systematic review of published studies.

    PubMed

    Ekwueme, Donatus U; Stroud, Leonardo A; Chen, Yanjing

    2007-10-01

    The reported estimates of the economic costs associated with prostate cancer screening, diagnostic testing, and clinical staging are substantial. However, the resource costs (i.e., factors such as physician's time, laboratory tests, patient's time away from work) included in these estimates are unknown. We examined the resource costs for prostate cancer screening, diagnostic tests, and staging; examined how these costs differ in the United States from costs in other industrialized countries; and estimated the cost per man screened for prostate cancer, per man given a diagnostic test, and per man given a clinically staged diagnosis of this disease. We searched the electronic databases MEDLINE, EMBASE, and CINAHL for articles and reports on prostate cancer published from January 1980 through December 2003. Studies were selected according to the following criteria: the article was published in English; the full text was available for review; the study reported the resource or input cost data used to estimate the cost of prostate cancer testing, diagnosing, or clinical staging; and the study was conducted in an established market economy. We used descriptive statistics, weighted mean, and Monte Carlo simulation methods to pool and analyze the abstracted data. Of 262 studies examined, 28 met our selection criteria (15 from the United States and 13 from other industrialized countries). For studies conducted in the United States, the pooled baseline resource cost was $37.23 for screening with prostate-specific antigen (PSA) and $31.77 for screening with digital rectal examination (DRE). For studies conducted in other industrialized countries, the pooled baseline resource cost was $30.92 for screening with PSA and $33.54 for DRE. For diagnostic and staging methods, the variation in the resource costs between the United States and other industrialized countries was mixed. Because national health resources are limited, a decision about whether to invest in early detection of

  5. [Formula: see text]: Oblivious similarity based searching for encrypted data outsourced to an untrusted domain.

    PubMed

    Pervez, Zeeshan; Ahmad, Mahmood; Khattak, Asad Masood; Ramzan, Naeem; Khan, Wajahat Ali

    2017-01-01

    Public cloud storage services are becoming prevalent and myriad data sharing, archiving and collaborative services have emerged which harness the pay-as-you-go business model of public cloud. To ensure privacy and confidentiality often encrypted data is outsourced to such services, which further complicates the process of accessing relevant data by using search queries. Search over encrypted data schemes solve this problem by exploiting cryptographic primitives and secure indexing to identify outsourced data that satisfy the search criteria. Almost all of these schemes rely on exact matching between the encrypted data and search criteria. A few schemes which extend the notion of exact matching to similarity based search, lack realism as those schemes rely on trusted third parties or due to increase storage and computational complexity. In this paper we propose Oblivious Similarity based Search ([Formula: see text]) for encrypted data. It enables authorized users to model their own encrypted search queries which are resilient to typographical errors. Unlike conventional methodologies, [Formula: see text] ranks the search results by using similarity measure offering a better search experience than exact matching. It utilizes encrypted bloom filter and probabilistic homomorphic encryption to enable authorized users to access relevant data without revealing results of search query evaluation process to the untrusted cloud service provider. Encrypted bloom filter based search enables [Formula: see text] to reduce search space to potentially relevant encrypted data avoiding unnecessary computation on public cloud. The efficacy of [Formula: see text] is evaluated on Google App Engine for various bloom filter lengths on different cloud configurations.

  6. Novel web service selection model based on discrete group search.

    PubMed

    Zhai, Jie; Shao, Zhiqing; Guo, Yi; Zhang, Haiteng

    2014-01-01

    In our earlier work, we present a novel formal method for the semiautomatic verification of specifications and for describing web service composition components by using abstract concepts. After verification, the instantiations of components were selected to satisfy the complex service performance constraints. However, selecting an optimal instantiation, which comprises different candidate services for each generic service, from a large number of instantiations is difficult. Therefore, we present a new evolutionary approach on the basis of the discrete group search service (D-GSS) model. With regard to obtaining the optimal multiconstraint instantiation of the complex component, the D-GSS model has competitive performance compared with other service selection models in terms of accuracy, efficiency, and ability to solve high-dimensional service composition component problems. We propose the cost function and the discrete group search optimizer (D-GSO) algorithm and study the convergence of the D-GSS model through verification and test cases.

  7. Swarm Robots Search for Multiple Targets Based on an Improved Grouping Strategy.

    PubMed

    Tang, Qirong; Ding, Lu; Yu, Fangchao; Zhang, Yuan; Li, Yinghao; Tu, Haibo

    2017-03-14

    Swarm robots search for multiple targets in collaboration in unknown environments has been addressed in this paper. An improved grouping strategy based on constriction factors Particle Swarm Optimization is proposed. Robots are grouped under this strategy after several iterations of stochastic movements, which considers the influence range of targets and environmental information they have sensed. The group structure may change dynamically and each group focuses on searching one target. All targets are supposed to be found finally. Obstacle avoidance is considered during the search process. Simulation compared with previous method demonstrates the adaptability, accuracy and efficiency of the proposed strategy in multiple targets searching.

  8. [Changing methods of pain- and fear-relief in dental treatments based on reports published in 'Fogorvosi Szemle'].

    PubMed

    Tarján, Ildikó; Gábris, Katalin

    2008-12-01

    In the dental practice--for more than a 100 years--it has been a vital topic how to prevent, eliminate, or at least relieve pain and fear associated with dental treatments. 'Fogorvosi Szemle,' the scientific journal of the Hungarian Dental Association is now a 100 years old. Authors present how the approaches and methods of relieving pain and fear have changed in the past century, based on the reports published in this journal. The reports are grouped in three main topics: local anaesthetics and sedatives; ambulatory narcosis and sedative analgesia; hypnosis and hypnotherapy. Based on the publications of the last one hundred years, it can be concluded that the Hungarian dental practice has followed the trends and principles of the well-known international dental schools.

  9. A rate-constrained fast full-search algorithm based on block sum pyramid.

    PubMed

    Song, Byung Cheol; Chun, Kang-Wook; Ra, Jong Beom

    2005-03-01

    This paper presents a fast full-search algorithm (FSA) for rate-constrained motion estimation. The proposed algorithm, which is based on the block sum pyramid frame structure, successively eliminates unnecessary search positions according to rate-constrained criterion. This algorithm provides the identical estimation performance to a conventional FSA having rate constraint, while achieving considerable reduction in computation.

  10. Effect of Reading Ability and Internet Experience on Keyword-Based Image Search

    ERIC Educational Resources Information Center

    Lei, Pei-Lan; Lin, Sunny S. J.; Sun, Chuen-Tsai

    2013-01-01

    Image searches are now crucial for obtaining information, constructing knowledge, and building successful educational outcomes. We investigated how reading ability and Internet experience influence keyword-based image search behaviors and performance. We categorized 58 junior-high-school students into four groups of high/low reading ability and…

  11. Relevant Term Suggestion in Interactive Web Search Based on Contextual Information in Query Session Logs.

    ERIC Educational Resources Information Center

    Huang, Chien-Kang; Chien, Lee-Feng; Oyang, Yen-Jen

    2003-01-01

    Proposes an effective term suggestion approach to interactive Web searches. Explains a log-based approach to relevant term extraction and term suggestion where relevant terms suggested for a user query are those that co-occur in similar query sessions from search engine logs rather than in the retrieved documents. (Author/LRW)

  12. Effect of Reading Ability and Internet Experience on Keyword-Based Image Search

    ERIC Educational Resources Information Center

    Lei, Pei-Lan; Lin, Sunny S. J.; Sun, Chuen-Tsai

    2013-01-01

    Image searches are now crucial for obtaining information, constructing knowledge, and building successful educational outcomes. We investigated how reading ability and Internet experience influence keyword-based image search behaviors and performance. We categorized 58 junior-high-school students into four groups of high/low reading ability and…

  13. Impact of Glaucoma and Dry Eye on Text-Based Searching

    PubMed Central

    Sun, Michelle J.; Rubin, Gary S.; Akpek, Esen K.; Ramulu, Pradeep Y.

    2017-01-01

    Purpose We determine if visual field loss from glaucoma and/or measures of dry eye severity are associated with difficulty searching, as judged by slower search times on a text-based search task. Methods Glaucoma patients with bilateral visual field (VF) loss, patients with clinically significant dry eye, and normally-sighted controls were enrolled from the Wilmer Eye Institute clinics. Subjects searched three Yellow Pages excerpts for a specific phone number, and search time was recorded. Results A total of 50 glaucoma subjects, 40 dry eye subjects, and 45 controls completed study procedures. On average, glaucoma patients exhibited 57% longer search times compared to controls (95% confidence interval [CI], 26%–96%, P < 0.001), and longer search times were noted among subjects with greater VF loss (P < 0.001), worse contrast sensitivity (P < 0.001), and worse visual acuity (P = 0.026). Dry eye subjects demonstrated similar search times compared to controls, though worse Ocular Surface Disease Index (OSDI) vision-related subscores were associated with longer search times (P < 0.01). Search times showed no association with OSDI symptom subscores (P = 0.20) or objective measures of dry eye (P > 0.08 for Schirmer's testing without anesthesia, corneal fluorescein staining, and tear film breakup time). Conclusions Text-based visual search is slower for glaucoma patients with greater levels of VF loss and dry eye patients with greater self-reported visual difficulty, and these difficulties may contribute to decreased quality of life in these groups. Translational Relevance Visual search is impaired in glaucoma and dry eye groups compared to controls, highlighting the need for compensatory strategies and tools to assist individuals in overcoming their deficiencies. PMID:28670502

  14. Impact of Glaucoma and Dry Eye on Text-Based Searching.

    PubMed

    Sun, Michelle J; Rubin, Gary S; Akpek, Esen K; Ramulu, Pradeep Y

    2017-06-01

    We determine if visual field loss from glaucoma and/or measures of dry eye severity are associated with difficulty searching, as judged by slower search times on a text-based search task. Glaucoma patients with bilateral visual field (VF) loss, patients with clinically significant dry eye, and normally-sighted controls were enrolled from the Wilmer Eye Institute clinics. Subjects searched three Yellow Pages excerpts for a specific phone number, and search time was recorded. A total of 50 glaucoma subjects, 40 dry eye subjects, and 45 controls completed study procedures. On average, glaucoma patients exhibited 57% longer search times compared to controls (95% confidence interval [CI], 26%-96%, P < 0.001), and longer search times were noted among subjects with greater VF loss (P < 0.001), worse contrast sensitivity (P < 0.001), and worse visual acuity (P = 0.026). Dry eye subjects demonstrated similar search times compared to controls, though worse Ocular Surface Disease Index (OSDI) vision-related subscores were associated with longer search times (P < 0.01). Search times showed no association with OSDI symptom subscores (P = 0.20) or objective measures of dry eye (P > 0.08 for Schirmer's testing without anesthesia, corneal fluorescein staining, and tear film breakup time). Text-based visual search is slower for glaucoma patients with greater levels of VF loss and dry eye patients with greater self-reported visual difficulty, and these difficulties may contribute to decreased quality of life in these groups. Visual search is impaired in glaucoma and dry eye groups compared to controls, highlighting the need for compensatory strategies and tools to assist individuals in overcoming their deficiencies.

  15. Supervised learning of tools for content-based search of image databases

    NASA Astrophysics Data System (ADS)

    Delanoy, Richard L.

    1996-03-01

    A computer environment, called the Toolkit for Image Mining (TIM), is being developed with the goal of enabling users with diverse interests and varied computer skills to create search tools for content-based image retrieval and other pattern matching tasks. Search tools are generated using a simple paradigm of supervised learning that is based on the user pointing at mistakes of classification made by the current search tool. As mistakes are identified, a learning algorithm uses the identified mistakes to build up a model of the user's intentions, construct a new search tool, apply the search tool to a test image, display the match results as feedback to the user, and accept new inputs from the user. Search tools are constructed in the form of functional templates, which are generalized matched filters capable of knowledge- based image processing. The ability of this system to learn the user's intentions from experience contrasts with other existing approaches to content-based image retrieval that base searches on the characteristics of a single input example or on a predefined and semantically- constrained textual query. Currently, TIM is capable of learning spectral and textural patterns, but should be adaptable to the learning of shapes, as well. Possible applications of TIM include not only content-based image retrieval, but also quantitative image analysis, the generation of metadata for annotating images, data prioritization or data reduction in bandwidth-limited situations, and the construction of components for larger, more complex computer vision algorithms.

  16. Generating MEDLINE search strategies using a librarian knowledge-based system.

    PubMed Central

    Peng, P.; Aguirre, A.; Johnson, S. B.; Cimino, J. J.

    1993-01-01

    We describe a librarian knowledge-based system that generates a search strategy from a query representation based on a user's information need. Together with the natural language parser AQUA, the system functions as a human/computer interface, which translates a user query from free text into a BRS Onsite search formulation, for searching the MEDLINE bibliographic database. In the system, conceptual graphs are used to represent the user's information need. The UMLS Metathesaurus and Semantic Net are used as the key knowledge sources in building the knowledge base. PMID:8130544

  17. Vaidurya: a multiple-ontology, concept-based, context-sensitive clinical-guideline search engine.

    PubMed

    Moskovitch, Robert; Shahar, Yuval

    2009-02-01

    We designed and implemented a generic search engine (Vaidurya), as part of our Digital clinical-Guideline Library (DeGeL) framework. Two search methods were implemented in addition to full-text search: (1) concept-based search, which relies on pre-indexing the guidelines in a clinically meaningful fashion, and (2) context-sensitive search, which relies on first semi-structuring the guidelines according to a given ontology, then searching for terms within specific labeled text segments. The Vaidurya engine is fully functional and is used within the DeGeL system. We describe the Vaidurya ontological and algorithmic framework; we also briefly summarize the results of a detailed evaluation in the clinical-guideline domain, demonstrating that both concept-based and context-sensitive ontology-independent search are highly feasible and significantly improve on free text search retrieval performance. We conclude by analyzing the limitations and advantages of the approach, and the steps that we have started to take to extend it based on user feedback.

  18. Fine-grained Database Field Search Using Attribute-Based Encryption for E-Healthcare Clouds.

    PubMed

    Guo, Cheng; Zhuang, Ruhan; Jie, Yingmo; Ren, Yizhi; Wu, Ting; Choo, Kim-Kwang Raymond

    2016-11-01

    An effectively designed e-healthcare system can significantly enhance the quality of access and experience of healthcare users, including facilitating medical and healthcare providers in ensuring a smooth delivery of services. Ensuring the security of patients' electronic health records (EHRs) in the e-healthcare system is an active research area. EHRs may be outsourced to a third-party, such as a community healthcare cloud service provider for storage due to cost-saving measures. Generally, encrypting the EHRs when they are stored in the system (i.e. data-at-rest) or prior to outsourcing the data is used to ensure data confidentiality. Searchable encryption (SE) scheme is a promising technique that can ensure the protection of private information without compromising on performance. In this paper, we propose a novel framework for controlling access to EHRs stored in semi-trusted cloud servers (e.g. a private cloud or a community cloud). To achieve fine-grained access control for EHRs, we leverage the ciphertext-policy attribute-based encryption (CP-ABE) technique to encrypt tables published by hospitals, including patients' EHRs, and the table is stored in the database with the primary key being the patient's unique identity. Our framework can enable different users with different privileges to search on different database fields. Differ from previous attempts to secure outsourcing of data, we emphasize the control of the searches of the fields within the database. We demonstrate the utility of the scheme by evaluating the scheme using datasets from the University of California, Irvine.

  19. Face sketch synthesis via sparse representation-based greedy search.

    PubMed

    Shengchuan Zhang; Xinbo Gao; Nannan Wang; Jie Li; Mingjin Zhang

    2015-08-01

    Face sketch synthesis has wide applications in digital entertainment and law enforcement. Although there is much research on face sketch synthesis, most existing algorithms cannot handle some nonfacial factors, such as hair style, hairpins, and glasses if these factors are excluded in the training set. In addition, previous methods only work on well controlled conditions and fail on images with different backgrounds and sizes as the training set. To this end, this paper presents a novel method that combines both the similarity between different image patches and prior knowledge to synthesize face sketches. Given training photo-sketch pairs, the proposed method learns a photo patch feature dictionary from the training photo patches and replaces the photo patches with their sparse coefficients during the searching process. For a test photo patch, we first obtain its sparse coefficient via the learnt dictionary and then search its nearest neighbors (candidate patches) in the whole training photo patches with sparse coefficients. After purifying the nearest neighbors with prior knowledge, the final sketch corresponding to the test photo can be obtained by Bayesian inference. The contributions of this paper are as follows: 1) we relax the nearest neighbor search area from local region to the whole image without too much time consuming and 2) our method can produce nonfacial factors that are not contained in the training set and is robust against image backgrounds and can even ignore the alignment and image size aspects of test photos. Our experimental results show that the proposed method outperforms several state-of-the-arts in terms of perceptual and objective metrics.

  20. Graphics-based intelligent search and abstracting using Data Modeling

    NASA Astrophysics Data System (ADS)

    Jaenisch, Holger M.; Handley, James W.; Case, Carl T.; Songy, Claude G.

    2002-11-01

    This paper presents an autonomous text and context-mining algorithm that converts text documents into point clouds for visual search cues. This algorithm is applied to the task of data-mining a scriptural database comprised of the Old and New Testaments from the Bible and the Book of Mormon, Doctrine and Covenants, and the Pearl of Great Price. Results are generated which graphically show the scripture that represents the average concept of the database and the mining of the documents down to the verse level.

  1. The Search for Extension: 7 Steps to Help People Find Research-Based Information on the Internet

    ERIC Educational Resources Information Center

    Hill, Paul; Rader, Heidi B.; Hino, Jeff

    2012-01-01

    For Extension's unbiased, research-based content to be found by people searching the Internet, it needs to be organized in a way conducive to the ranking criteria of a search engine. With proper web design and search engine optimization techniques, Extension's content can be found, recognized, and properly indexed by search engines and…

  2. The Search for Extension: 7 Steps to Help People Find Research-Based Information on the Internet

    ERIC Educational Resources Information Center

    Hill, Paul; Rader, Heidi B.; Hino, Jeff

    2012-01-01

    For Extension's unbiased, research-based content to be found by people searching the Internet, it needs to be organized in a way conducive to the ranking criteria of a search engine. With proper web design and search engine optimization techniques, Extension's content can be found, recognized, and properly indexed by search engines and…

  3. Incremental Learning of Context Free Grammars by Parsing-Based Rule Generation and Rule Set Search

    NASA Astrophysics Data System (ADS)

    Nakamura, Katsuhiko; Hoshina, Akemi

    This paper discusses recent improvements and extensions in Synapse system for inductive inference of context free grammars (CFGs) from sample strings. Synapse uses incremental learning, rule generation based on bottom-up parsing, and the search for rule sets. The form of production rules in the previous system is extended from Revised Chomsky Normal Form A→βγ to Extended Chomsky Normal Form, which also includes A→B, where each of β and γ is either a terminal or nonterminal symbol. From the result of bottom-up parsing, a rule generation mechanism synthesizes minimum production rules required for parsing positive samples. Instead of inductive CYK algorithm in the previous version of Synapse, the improved version uses a novel rule generation method, called ``bridging,'' which bridges the lacked part of the derivation tree for the positive string. The improved version also employs a novel search strategy, called serial search in addition to minimum rule set search. The synthesis of grammars by the serial search is faster than the minimum set search in most cases. On the other hand, the size of the generated CFGs is generally larger than that by the minimum set search, and the system can find no appropriate grammar for some CFL by the serial search. The paper shows experimental results of incremental learning of several fundamental CFGs and compares the methods of rule generation and search strategies.

  4. Rank-Based Similarity Search: Reducing the Dimensional Dependence.

    PubMed

    Houle, Michael E; Nett, Michael

    2015-01-01

    This paper introduces a data structure for k-NN search, the Rank Cover Tree (RCT), whose pruning tests rely solely on the comparison of similarity values; other properties of the underlying space, such as the triangle inequality, are not employed. Objects are selected according to their ranks with respect to the query object, allowing much tighter control on the overall execution costs. A formal theoretical analysis shows that with very high probability, the RCT returns a correct query result in time that depends very competitively on a measure of the intrinsic dimensionality of the data set. The experimental results for the RCT show that non-metric pruning strategies for similarity search can be practical even when the representational dimension of the data is extremely high. They also show that the RCT is capable of meeting or exceeding the level of performance of state-of-the-art methods that make use of metric pruning or other selection tests involving numerical constraints on distance values.

  5. A geometry-based image search engine for advanced RADARSAT-1/2 GIS applications

    NASA Astrophysics Data System (ADS)

    Kotamraju, Vinay; Rabus, Bernhard; Busler, Jennifer

    2012-06-01

    Space-borne Synthetic Aperture Radar (SAR) sensors, such as RADARSAT-1 and -2, enable a multitude of defense and security applications owing to their unique capabilities of cloud penetration, day/night imaging and multi-polarization imaging. As a result, advanced SAR image time series exploitation techniques such as Interferometric SAR (InSAR) and Radargrammetry are now routinely used in applications such as underground tunnel monitoring, infrastructure monitoring and DEM generation. Imaging geometry, as determined by the satellite orbit and imaged terrain, plays a critical role in the success of such techniques. This paper describes the architecture and the current status of development of a geometry-based search engine that allows the search and visualization of archived and future RADARSAT-1 and -2 images appropriate for a variety of advanced SAR techniques and applications. Key features of the search engine's scalable architecture include (a) Interactive GIS-based visualization of the search results; (b) A client-server architecture for online access that produces up-to-date searches of the archive images and that can, in future, be extended to acquisition planning; (c) A techniquespecific search mode, wherein an expert user explicitly sets search parameters to find appropriate images for advanced SAR techniques such as InSAR and Radargrammetry; (d) A future application-specific search mode, wherein all search parameters implicitly default to preset values according to the application of choice such as tunnel monitoring, DEM generation and deformation mapping; (f) Accurate baseline calculations for InSAR searches, and, optimum beam configuration for Radargrammetric searches; (g) Simulated quick look images and technique-specific sensitivity maps in the future.

  6. A comparative evaluation of full-text, concept-based, and context-sensitive search.

    PubMed

    Moskovitch, Robert; Martins, Susana B; Behiri, Eytan; Weiss, Aviram; Shahar, Yuval

    2007-01-01

    Study comparatively (1) concept-based search, using documents pre-indexed by a conceptual hierarchy; (2) context-sensitive search, using structured, labeled documents; and (3) traditional full-text search. Hypotheses were: (1) more contexts lead to better retrieval accuracy; and (2) adding concept-based search to the other searches would improve upon their baseline performances. Use our Vaidurya architecture, for search and retrieval evaluation, of structured documents classified by a conceptual hierarchy, on a clinical guidelines test collection. Precision computed at different levels of recall to assess the contribution of the retrieval methods. Comparisons of precisions done with recall set at 0.5, using t-tests. Performance increased monotonically with the number of query context elements. Adding context-sensitive elements, mean improvement was 11.1% at recall 0.5. With three contexts, mean query precision was 42% +/- 17% (95% confidence interval [CI], 31% to 53%); with two contexts, 32% +/- 13% (95% CI, 27% to 38%); and one context, 20% +/- 9% (95% CI, 15% to 24%). Adding context-based queries to full-text queries monotonically improved precision beyond the 0.4 level of recall. Mean improvement was 4.5% at recall 0.5. Adding concept-based search to full-text search improved precision to 19.4% at recall 0.5. The study demonstrated usefulness of concept-based and context-sensitive queries for enhancing the precision of retrieval from a digital library of semi-structured clinical guideline documents. Concept-based searches outperformed free-text queries, especially when baseline precision was low. In general, the more ontological elements used in the query, the greater the resulting precision.

  7. Transformation of an uncertain video search pipeline to a sketch-based visual analytics loop.

    PubMed

    Legg, Philip A; Chung, David H S; Parry, Matthew L; Bown, Rhodri; Jones, Mark W; Griffiths, Iwan W; Chen, Min

    2013-12-01

    Traditional sketch-based image or video search systems rely on machine learning concepts as their core technology. However, in many applications, machine learning alone is impractical since videos may not be semantically annotated sufficiently, there may be a lack of suitable training data, and the search requirements of the user may frequently change for different tasks. In this work, we develop a visual analytics systems that overcomes the shortcomings of the traditional approach. We make use of a sketch-based interface to enable users to specify search requirement in a flexible manner without depending on semantic annotation. We employ active machine learning to train different analytical models for different types of search requirements. We use visualization to facilitate knowledge discovery at the different stages of visual analytics. This includes visualizing the parameter space of the trained model, visualizing the search space to support interactive browsing, visualizing candidature search results to support rapid interaction for active learning while minimizing watching videos, and visualizing aggregated information of the search results. We demonstrate the system for searching spatiotemporal attributes from sports video to identify key instances of the team and player performance.

  8. Soft-Decision Decoding of Binary Linear Block Codes Based on an Iterative Search Algorithm

    NASA Technical Reports Server (NTRS)

    Lin, Shu; Kasami, Tadao; Moorthy, H. T.

    1997-01-01

    This correspondence presents a suboptimum soft-decision decoding scheme for binary linear block codes based on an iterative search algorithm. The scheme uses an algebraic decoder to iteratively generate a sequence of candidate codewords one at a time using a set of test error patterns that are constructed based on the reliability information of the received symbols. When a candidate codeword is generated, it is tested based on an optimality condition. If it satisfies the optimality condition, then it is the most likely (ML) codeword and the decoding stops. If it fails the optimality test, a search for the ML codeword is conducted in a region which contains the ML codeword. The search region is determined by the current candidate codeword and the reliability of the received symbols. The search is conducted through a purged trellis diagram for the given code using the Viterbi algorithm. If the search fails to find the ML codeword, a new candidate is generated using a new test error pattern, and the optimality test and search are renewed. The process of testing and search continues until either the MEL codeword is found or all the test error patterns are exhausted and the decoding process is terminated. Numerical results show that the proposed decoding scheme achieves either practically optimal performance or a performance only a fraction of a decibel away from the optimal maximum-likelihood decoding with a significant reduction in decoding complexity compared with the Viterbi decoding based on the full trellis diagram of the codes.

  9. Model-Based Systems Engineering in the Execution of Search and Rescue Operations

    DTIC Science & Technology

    2015-09-01

    development of a design reference mission, this thesis illustrates how a search and rescue architecture can undergo multiple levels of model-based analysis...domain. Then, other modelers can build upon the work presented here in order to assess any architecture aspect from different operating procedures to... architecture but also any system today and in the future. 14. SUBJECT TERMS model-based systems engineering, search and rescue, modeling

  10. Installation Restoration Program. Phase I: Records Search Goodfellow Air Force Base, Texas.

    DTIC Science & Technology

    1985-03-01

    1980. Paleozic Stratigrapohy of the Llano Region, Texas . West Texas Geological Society. Wermund, E.G. and Jenkins, W.A. Jr. 1969. Late Pennsylvanian...AD-A±54 713 INSTALLATION RESTORATION PROGRAM PHASE I: RECORDS ±4 SEARCH GOODFELLON AIR FORCE BASE TEXAS (U) ENVIRONMENTAL SCIENCE AND ENGINEERING INC...SEARCH GOODFELLW AIR FORCE BASE TEXAS 4. Prepared for: UNITED STATES AIR FORCE HQ A1ESC/IZVP Tyndall AFB, Florida and HQ ATC/DEEV Randolph APB, Texas

  11. B-tree search reinforcement learning for model based intelligent agent

    NASA Astrophysics Data System (ADS)

    Bhuvaneswari, S.; Vignashwaran, R.

    2013-03-01

    Agents trained by learning techniques provide a powerful approximation of active solutions for naive approaches. In this study using B - Trees implying reinforced learning the data search for information retrieval is moderated to achieve accuracy with minimum search time. The impact of variables and tactics applied in training are determined using reinforcement learning. Agents based on these techniques perform satisfactory baseline and act as finite agents based on the predetermined model against competitors from the course.

  12. A phenomenological relative biological effectiveness (RBE) model for proton therapy based on all published in vitro cell survival data

    NASA Astrophysics Data System (ADS)

    McNamara, Aimee L.; Schuemann, Jan; Paganetti, Harald

    2015-11-01

    Proton therapy treatments are currently planned and delivered using the assumption that the proton relative biological effectiveness (RBE) relative to photons is 1.1. This assumption ignores strong experimental evidence that suggests the RBE varies along the treatment field, i.e. with linear energy transfer (LET) and with tissue type. A recent review study collected over 70 experimental reports on proton RBE, providing a comprehensive dataset for predicting RBE for cell survival. Using this dataset we developed a model to predict proton RBE based on dose, dose average LET (LETd) and the ratio of the linear-quadratic model parameters for the reference radiation (α/β)x, as the tissue specific parameter. The proposed RBE model is based on the linear quadratic model and was derived from a nonlinear regression fit to 287 experimental data points. The proposed model predicts that the RBE increases with increasing LETd and decreases with increasing (α/β)x. This agrees with previous theoretical predictions on the relationship between RBE, LETd and (α/β)x. The model additionally predicts a decrease in RBE with increasing dose and shows a relationship between both α and β with LETd. Our proposed phenomenological RBE model is derived using the most comprehensive collection of proton RBE experimental data to date. Previously published phenomenological models, based on a limited data set, may have to be revised.

  13. Implied alignment: a synapomorphy-based multiple-sequence alignment method and its use in cladogram search

    NASA Technical Reports Server (NTRS)

    Wheeler, Ward C.

    2003-01-01

    A method to align sequence data based on parsimonious synapomorphy schemes generated by direct optimization (DO; earlier termed optimization alignment) is proposed. DO directly diagnoses sequence data on cladograms without an intervening multiple-alignment step, thereby creating topology-specific, dynamic homology statements. Hence, no multiple-alignment is required to generate cladograms. Unlike general and globally optimal multiple-alignment procedures, the method described here, implied alignment (IA), takes these dynamic homologies and traces them back through a single cladogram, linking the unaligned sequence positions in the terminal taxa via DO transformation series. These "lines of correspondence" link ancestor-descendent states and, when displayed as linearly arrayed columns without hypothetical ancestors, are largely indistinguishable from standard multiple alignment. Since this method is based on synapomorphy, the treatment of certain classes of insertion-deletion (indel) events may be different from that of other alignment procedures. As with all alignment methods, results are dependent on parameter assumptions such as indel cost and transversion:transition ratios. Such an IA could be used as a basis for phylogenetic search, but this would be questionable since the homologies derived from the implied alignment depend on its natal cladogram and any variance, between DO and IA + Search, due to heuristic approach. The utility of this procedure in heuristic cladogram searches using DO and the improvement of heuristic cladogram cost calculations are discussed. c2003 The Willi Hennig Society. Published by Elsevier Science (USA). All rights reserved.

  14. Implied alignment: a synapomorphy-based multiple-sequence alignment method and its use in cladogram search

    NASA Technical Reports Server (NTRS)

    Wheeler, Ward C.

    2003-01-01

    A method to align sequence data based on parsimonious synapomorphy schemes generated by direct optimization (DO; earlier termed optimization alignment) is proposed. DO directly diagnoses sequence data on cladograms without an intervening multiple-alignment step, thereby creating topology-specific, dynamic homology statements. Hence, no multiple-alignment is required to generate cladograms. Unlike general and globally optimal multiple-alignment procedures, the method described here, implied alignment (IA), takes these dynamic homologies and traces them back through a single cladogram, linking the unaligned sequence positions in the terminal taxa via DO transformation series. These "lines of correspondence" link ancestor-descendent states and, when displayed as linearly arrayed columns without hypothetical ancestors, are largely indistinguishable from standard multiple alignment. Since this method is based on synapomorphy, the treatment of certain classes of insertion-deletion (indel) events may be different from that of other alignment procedures. As with all alignment methods, results are dependent on parameter assumptions such as indel cost and transversion:transition ratios. Such an IA could be used as a basis for phylogenetic search, but this would be questionable since the homologies derived from the implied alignment depend on its natal cladogram and any variance, between DO and IA + Search, due to heuristic approach. The utility of this procedure in heuristic cladogram searches using DO and the improvement of heuristic cladogram cost calculations are discussed. c2003 The Willi Hennig Society. Published by Elsevier Science (USA). All rights reserved.

  15. Path Searching Based Fault Automated Recovery Scheme for Distribution Grid with DG

    NASA Astrophysics Data System (ADS)

    Xia, Lin; Qun, Wang; Hui, Xue; Simeng, Zhu

    2016-12-01

    Applying the method of path searching based on distribution network topology in setting software has a good effect, and the path searching method containing DG power source is also applicable to the automatic generation and division of planned islands after the fault. This paper applies path searching algorithm in the automatic division of planned islands after faults: starting from the switch of fault isolation, ending in each power source, and according to the line load that the searching path traverses and the load integrated by important optimized searching path, forming optimized division scheme of planned islands that uses each DG as power source and is balanced to local important load. Finally, COBASE software and distribution network automation software applied are used to illustrate the effectiveness of the realization of such automatic restoration program.

  16. The Search for Life on Other Planets: Sulfur-Based, Silicon-Based, Ammonia-Based Life

    NASA Astrophysics Data System (ADS)

    Rampelotto, H. Pabulo

    2010-02-01

    The search for extraterrestrial life is one of the most challenging and interesting scientific themes of the 21st century. This search has been guided by our understanding of the life's nature. Up to now, we only know life on Earth, which uses water as a solvent and the building blocks of which are based on carbon and oxygen. Hence, the search for extraterrestrial life has been the search for life as we know it as based on life which lives on Earth. However, living systems that may have originated elsewhere, even within our own solar system, could be unrecognizable compared with life here and thus not be detectable by telescopes and spacecraft landers designed to detect terrestrial biomolecules or their products.Therefore, we need to expand the boundaries of our Earth-centric concept of life and be open-minded and aware of the most general features of living systems. Life forms based on silicon, ammonia, and sulfur are among those who may have evolved on other worlds, and these possibilities are discussed.

  17. CKB - the compound knowledge base: a text based chemical search system.

    PubMed

    Walker, Matthew J; Hull, Richard D; Singh, Suresh B

    2002-01-01

    The Compound Knowledge Base (CKB) was developed as a means of locating structures and additional relevant information from a given known structural identifier. Any of Chemical Abstracts Service Registry Number, company code (code number the producing company refers to the chemical entity internally), generic name (trivial or class name), or trade name (name under which the compound is marketed) can be provided as a query. CKB will provide the remaining available information as well as the corresponding structure for any matching compound in the database. The interface to the Compound Knowledge Base is Internet/World Wide Web-based, using Netscape Navigator and the ChemDraw Pro Plugin, which allows Merck scientists quick and easy access to the database from their desktop. The design and implementation of the database and the search interface are herein detailed.

  18. Global polar geospatial information service retrieval based on search engine and ontology reasoning

    USGS Publications Warehouse

    Chen, Nengcheng; E, Dongcheng; Di, Liping; Gong, Jianya; Chen, Zeqiang

    2007-01-01

    In order to improve the access precision of polar geospatial information service on web, a new methodology for retrieving global spatial information services based on geospatial service search and ontology reasoning is proposed, the geospatial service search is implemented to find the coarse service from web, the ontology reasoning is designed to find the refined service from the coarse service. The proposed framework includes standardized distributed geospatial web services, a geospatial service search engine, an extended UDDI registry, and a multi-protocol geospatial information service client. Some key technologies addressed include service discovery based on search engine and service ontology modeling and reasoning in the Antarctic geospatial context. Finally, an Antarctica multi protocol OWS portal prototype based on the proposed methodology is introduced.

  19. Q-Learning-Based Adjustable Fixed-Phase Quantum Grover Search Algorithm

    NASA Astrophysics Data System (ADS)

    Guo, Ying; Shi, Wensha; Wang, Yijun; Hu, Jiankun

    2017-02-01

    We demonstrate that the rotation phase can be suitably chosen to increase the efficiency of the phase-based quantum search algorithm, leading to a dynamic balance between iterations and success probabilities of the fixed-phase quantum Grover search algorithm with Q-learning for a given number of solutions. In this search algorithm, the proposed Q-learning algorithm, which is a model-free reinforcement learning strategy in essence, is used for performing a matching algorithm based on the fraction of marked items λ and the rotation phase α. After establishing the policy function α = π(λ), we complete the fixed-phase Grover algorithm, where the phase parameter is selected via the learned policy. Simulation results show that the Q-learning-based Grover search algorithm (QLGA) enables fewer iterations and gives birth to higher success probabilities. Compared with the conventional Grover algorithms, it avoids the optimal local situations, thereby enabling success probabilities to approach one.

  20. Web-based learning strategies in combination with published guidelines to change practice of primary care professionals

    PubMed Central

    Robson, Jean

    2009-01-01

    Background Published clinical guidelines need to be combined with effective educational interventions to produce change in practice. Problem-based learning (PBL) groups are effective; however, research studies have not looked at change in practice following PBL that is independent of group interaction. Aim To determine whether clinical guidelines combined with modified PBL e-learning modules, in which dialogue between learners is replaced by interaction with a computer, could increase knowledge, result in changes in practice, and be acceptable to participants as a mode of modifying practice. Design of study Quantitative and qualitative methods. Setting Web-based application. Results Online PBL modules were studied by 45 primary care clinicians. Replacement of group functions by interaction with the computer was found to be an acceptable form of learning, and resulted in reported changes in practice among GPs choosing this method of study. This study shows that changes were independent of demonstrable knowledge gains. Conclusion Online PBL modules could complement other arms of guideline-implementation strategies. More work is needed to determine which groups would benefit most. PMID:19192374

  1. PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites.

    PubMed

    Cheng, Dean; Knox, Craig; Young, Nelson; Stothard, Paul; Damaraju, Sambasivarao; Wishart, David S

    2008-07-01

    A particular challenge in biomedical text mining is to find ways of handling 'comprehensive' or 'associative' queries such as 'Find all genes associated with breast cancer'. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe that a web-based tool that could support these searches would be quite useful. In response to this need, we have developed the PolySearch web server. PolySearch supports >50 different classes of queries against nearly a dozen different types of text, scientific abstract or bioinformatic databases. The typical query supported by PolySearch is 'Given X, find all Y's' where X or Y can be diseases, tissues, cell compartments, gene/protein names, SNPs, mutations, drugs and metabolites. PolySearch also exploits a variety of techniques in text mining and information retrieval to identify, highlight and rank informative abstracts, paragraphs or sentences. PolySearch's performance has been assessed in tasks such as gene synonym identification, protein-protein interaction identification and disease gene identification using a variety of manually assembled 'gold standard' text corpuses. Its f-measure on these tasks is 88, 81 and 79%, respectively. These values are between 5 and 50% better than other published tools. The server is freely available at http://wishart.biology.ualberta.ca/polysearch.

  2. PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites

    PubMed Central

    Cheng, Dean; Knox, Craig; Young, Nelson; Stothard, Paul; Damaraju, Sambasivarao; Wishart, David S.

    2008-01-01

    A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe that a web-based tool that could support these searches would be quite useful. In response to this need, we have developed the PolySearch web server. PolySearch supports >50 different classes of queries against nearly a dozen different types of text, scientific abstract or bioinformatic databases. The typical query supported by PolySearch is ‘Given X, find all Y's’ where X or Y can be diseases, tissues, cell compartments, gene/protein names, SNPs, mutations, drugs and metabolites. PolySearch also exploits a variety of techniques in text mining and information retrieval to identify, highlight and rank informative abstracts, paragraphs or sentences. PolySearch's performance has been assessed in tasks such as gene synonym identification, protein–protein interaction identification and disease gene identification using a variety of manually assembled ‘gold standard’ text corpuses. Its f-measure on these tasks is 88, 81 and 79%, respectively. These values are between 5 and 50% better than other published tools. The server is freely available at http://wishart.biology.ualberta.ca/polysearch PMID:18487273

  3. Knowledge-based personalized search engine for the Web-based Human Musculoskeletal System Resources (HMSR) in biomechanics.

    PubMed

    Dao, Tien Tuan; Hoang, Tuan Nha; Ta, Xuan Hien; Tho, Marie Christine Ho Ba

    2013-02-01

    Human musculoskeletal system resources of the human body are valuable for the learning and medical purposes. Internet-based information from conventional search engines such as Google or Yahoo cannot response to the need of useful, accurate, reliable and good-quality human musculoskeletal resources related to medical processes, pathological knowledge and practical expertise. In this present work, an advanced knowledge-based personalized search engine was developed. Our search engine was based on a client-server multi-layer multi-agent architecture and the principle of semantic web services to acquire dynamically accurate and reliable HMSR information by a semantic processing and visualization approach. A security-enhanced mechanism was applied to protect the medical information. A multi-agent crawler was implemented to develop a content-based database of HMSR information. A new semantic-based PageRank score with related mathematical formulas were also defined and implemented. As the results, semantic web service descriptions were presented in OWL, WSDL and OWL-S formats. Operational scenarios with related web-based interfaces for personal computers and mobile devices were presented and analyzed. Functional comparison between our knowledge-based search engine, a conventional search engine and a semantic search engine showed the originality and the robustness of our knowledge-based personalized search engine. In fact, our knowledge-based personalized search engine allows different users such as orthopedic patient and experts or healthcare system managers or medical students to access remotely into useful, accurate, reliable and good-quality HMSR information for their learning and medical purposes. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Embedding based on function approximation for large scale image search.

    PubMed

    Do, Thanh-Toan; Cheung, Ngai-Man

    2017-03-23

    The objective of this paper is to design an embedding method that maps local features describing an image (e.g. SIFT) to a higher dimensional representation useful for the image retrieval problem. First, motivated by the relationship between the linear approximation of a nonlinear function in high dimensional space and the stateof- the-art feature representation used in image retrieval, i.e., VLAD, we propose a new approach for the approximation. The embedded vectors resulted by the function approximation process are then aggregated to form a single representation for image retrieval. Second, in order to make the proposed embedding method applicable to large scale problem, we further derive its fast version in which the embedded vectors can be efficiently computed, i.e., in the closed-form. We compare the proposed embedding methods with the state of the art in the context of image search under various settings: when the images are represented by medium length vectors, short vectors, or binary vectors. The experimental results show that the proposed embedding methods outperform existing the state of the art on the standard public image retrieval benchmarks.

  5. Academic nightmares: Predatory publishing.

    PubMed

    Van Nuland, Sonya E; Rogers, Kem A

    2016-12-02

    Academic researchers who seek to publish their work are confronted daily with a barrage of e-mails from aggressive marketing campaigns that solicit them to publish their research with a specialized, often newly launched, journal. Known as predatory journals, they often promise high editorial and publishing standards, yet their exploitive business models, poor quality control, and minimal overall transparency victimize those researchers with limited academic experience and pave the way for low-quality articles that threaten the foundation of evidence-based research. Understanding how to identify these predatory journals requires thorough due diligence on the part of the submitting authors, and a commitment by reputable publishers, institutions, and researchers to publicly identify these predators and eliminate them as a threat to the careers of young scientists seeking to disseminate their work in scholarly journals. Anat Sci Educ. © 2016 American Association of Anatomists.

  6. Facilitating Novice Researchers in Project Publishing during the Doctoral Years and Beyond: A Hong Kong-Based Study

    ERIC Educational Resources Information Center

    Kwan, Becky Siu Chu

    2013-01-01

    This article examines the existing training that a group of supervisors in Hong Kong provide for their PhD students in helping them publish during their doctoral studies, and preparing them for the publishing demands in the early phase of their academic careers. The supervisors were interviewed about the types of training they provided for their…

  7. Venue Recommendation and Web Search Based on Anchor Text

    DTIC Science & Technology

    2014-11-01

    experimented with the use of anchor text representations in the language modeling framework, and base our runs ei- ther on full ClueWeb12 or the subset of...anchor text representations in the language modeling framework, and base our runs ei- ther on full ClueWeb12 or the subset of touristic aggregators...ClueWeb12- full anchor text , and run our proposed model based on this dataset. This model is exactly the same as Model-Anchor, but based on the

  8. A reliability measure of protein-protein interactions and a reliability measure-based search engine.

    PubMed

    Park, Byungkyu; Han, Kyungsook

    2010-02-01

    Many methods developed for estimating the reliability of protein-protein interactions are based on the topology of protein-protein interaction networks. This paper describes a new reliability measure for protein-protein interactions, which does not rely on the topology of protein interaction networks, but expresses biological information on functional roles, sub-cellular localisations and protein classes as a scoring schema. The new measure is useful for filtering many spurious interactions, as well as for estimating the reliability of protein interaction data. In particular, the reliability measure can be used to search protein-protein interactions with the desired reliability in databases. The reliability-based search engine is available at http://yeast.hpid.org. We believe this is the first search engine for interacting proteins, which is made available to public. The search engine and the reliability measure of protein interactions should provide useful information for determining proteins to focus on.

  9. Sensitive Ground-based Search for Sulfuretted Species on Mars

    NASA Astrophysics Data System (ADS)

    Khayat, Alain; Villanueva, G. L.; Mumma, M. J.; Riesen, T. E.; Tokunaga, A. T.

    2012-10-01

    We searched for active release of gases on Mars during mid Northern Spring and early Northern Summer seasons, between Ls= 34° and Ls= 110°. The targeted volcanic areas, Tharsis and Syrtis Major, were observed during the interval 23 Nov. 2011 to 13 May 2012, using the high resolution infrared spectrometer (CSHELL) on NASA's Infrared Telescope Facility (NASA/IRTF) and the ultra-high resolution heterodyne receiver (Barney) at the Caltech Submillimeter Observatory (CSO). The two main reservoirs of atmospheric sulfur on Mars are expected to be SO2 and H2S. Because these two species have relatively short photochemical lifetimes, 160 and 9 days respectively (Wong et al. 2004), they stand as powerful indicators of recent activity. Carbonyl sulfide (OCS) is the expected end-product of the reactions between sulfuretted species and other molecules in the Martian atmosphere. Our multi-band survey targeted SO2, SO and H2S at their rotational transitions at 346.523 GHz, 304.078 GHz and 300.505 GHz respectively, and OCS in its combination band (ν1+ν3) at 3.42 µm and its fundamental band (ν3) centered at 4.85 µm. The radiative transfer model used to derive abundance ratios for these species was validated by performing line-inversion retrievals on the carbon monoxide (CO) strong rotational (3-2) line at sub-mm wavelengths (rest frequency 345.796 GHz). Preliminary results and abundance ratios for SO2, H2S, SO, OCS and CO will be presented. We gratefully acknowledge support from the NASA Planetary Astronomy Program (AK, ATT, MJM), NASA Astrobiology Institute (MJM), NASA Planetary Atmospheres Program (GLV), and NSF grant number AST-0838261 to support graduate students at the CSO (AK). References: Wong, A.S., Atreya, S. K., Formisano, V., Encrenaz, T., Ignatiev, N.I., "Atmospheric photochemistry above possible martian hot spots", Advances in Space Research, 33 (2004) 2236-2239.

  10. Visibiome: an efficient microbiome search engine based on a scalable, distributed architecture.

    PubMed

    Azman, Syafiq Kamarul; Anwar, Muhammad Zohaib; Henschel, Andreas

    2017-07-24

    Given the current influx of 16S rRNA profiles of microbiota samples, it is conceivable that large amounts of them eventually are available for search, comparison and contextualization with respect to novel samples. This process facilitates the identification of similar compositional features in microbiota elsewhere and therefore can help to understand driving factors for microbial community assembly. We present Visibiome, a microbiome search engine that can perform exhaustive, phylogeny based similarity search and contextualization of user-provided samples against a comprehensive dataset of 16S rRNA profiles environments, while tackling several computational challenges. In order to scale to high demands, we developed a distributed system that combines web framework technology, task queueing and scheduling, cloud computing and a dedicated database server. To further ensure speed and efficiency, we have deployed Nearest Neighbor search algorithms, capable of sublinear searches in high-dimensional metric spaces in combination with an optimized Earth Mover Distance based implementation of weighted UniFrac. The search also incorporates pairwise (adaptive) rarefaction and optionally, 16S rRNA copy number correction. The result of a query microbiome sample is the contextualization against a comprehensive database of microbiome samples from a diverse range of environments, visualized through a rich set of interactive figures and diagrams, including barchart-based compositional comparisons and ranking of the closest matches in the database. Visibiome is a convenient, scalable and efficient framework to search microbiomes against a comprehensive database of environmental samples. The search engine leverages a popular but computationally expensive, phylogeny based distance metric, while providing numerous advantages over the current state of the art tool.

  11. A Nonhomogeneous Cuckoo Search Algorithm Based on Quantum Mechanism for Real Parameter Optimization.

    PubMed

    Cheung, Ngaam J; Ding, Xue-Ming; Shen, Hong-Bin

    2017-02-01

    Cuckoo search (CS) algorithm is a nature-inspired search algorithm, in which all the individuals have identical search behaviors. However, this simple homogeneous search behavior is not always optimal to find the potential solution to a special problem, and it may trap the individuals into local regions leading to premature convergence. To overcome the drawback, this paper presents a new variant of CS algorithm with nonhomogeneous search strategies based on quantum mechanism to enhance search ability of the classical CS algorithm. Featured contributions in this paper include: 1) quantum-based strategy is developed for nonhomogeneous update laws and 2) we, for the first time, present a set of theoretical analyses on CS algorithm as well as the proposed algorithm, respectively, and conclude a set of parameter boundaries guaranteeing the convergence of the CS algorithm and the proposed algorithm. On 24 benchmark functions, we compare our method with five existing CS-based methods and other ten state-of-the-art algorithms. The numerical results demonstrate that the proposed algorithm is significantly better than the original CS algorithm and the rest of compared methods according to two nonparametric tests.

  12. General Quantum Meet-in-the-Middle Search Algorithm Based on Target Solution of Fixed Weight

    NASA Astrophysics Data System (ADS)

    Fu, Xiang-Qun; Bao, Wan-Su; Wang, Xiang; Shi, Jian-Hong

    2016-10-01

    Similar to the classical meet-in-the-middle algorithm, the storage and computation complexity are the key factors that decide the efficiency of the quantum meet-in-the-middle algorithm. Aiming at the target vector of fixed weight, based on the quantum meet-in-the-middle algorithm, the algorithm for searching all n-product vectors with the same weight is presented, whose complexity is better than the exhaustive search algorithm. And the algorithm can reduce the storage complexity of the quantum meet-in-the-middle search algorithm. Then based on the algorithm and the knapsack vector of the Chor-Rivest public-key crypto of fixed weight d, we present a general quantum meet-in-the-middle search algorithm based on the target solution of fixed weight, whose computational complexity is \\sumj = 0d {(O(\\sqrt {Cn - k + 1d - j }) + O(C_kj log C_k^j))} with Σd i =0 Ck i memory cost. And the optimal value of k is given. Compared to the quantum meet-in-the-middle search algorithm for knapsack problem and the quantum algorithm for searching a target solution of fixed weight, the computational complexity of the algorithm is lower. And its storage complexity is smaller than the quantum meet-in-the-middle-algorithm. Supported by the National Basic Research Program of China under Grant No. 2013CB338002 and the National Natural Science Foundation of China under Grant No. 61502526

  13. The NeuARt II system: a viewing tool for neuroanatomical data based on published neuroanatomical atlases

    PubMed Central

    Burns, Gully APC; Cheng, Wei-Cheng; Thompson, Richard H; Swanson, Larry W

    2006-01-01

    Background Anatomical studies of neural circuitry describing the basic wiring diagram of the brain produce intrinsically spatial, highly complex data of great value to the neuroscience community. Published neuroanatomical atlases provide a spatial framework for these studies. We have built an informatics framework based on these atlases for the representation of neuroanatomical knowledge. This framework not only captures current methods of anatomical data acquisition and analysis, it allows these studies to be collated, compared and synthesized within a single system. Results We have developed an atlas-viewing application ('NeuARt II') in the Java language with unique functional properties. These include the ability to use copyrighted atlases as templates within which users may view, save and retrieve data-maps and annotate them with volumetric delineations. NeuARt II also permits users to view multiple levels on multiple atlases at once. Each data-map in this system is simply a stack of vector images with one image per atlas level, so any set of accurate drawings made onto a supported atlas (in vector graphics format) could be uploaded into NeuARt II. Presently the database is populated with a corpus of high-quality neuroanatomical data from the laboratory of Dr Larry Swanson (consisting 64 highly-detailed maps of PHAL tract-tracing experiments, made up of 1039 separate drawings that were published in 27 primary research publications over 17 years). Herein we take selective examples from these data to demonstrate the features of NeuArt II. Our informatics tool permits users to browse, query and compare these maps. The NeuARt II tool operates within a bioinformatics knowledge management platform (called 'NeuroScholar') either as a standalone or a plug-in application. Conclusion Anatomical localization is fundamental to neuroscientific work and atlases provide an easily-understood framework that is widely used by neuroanatomists and non-neuroanatomists alike. Neu

  14. Optimal clustering of MGs based on droop controller for improving reliability using a hybrid of harmony search and genetic algorithms.

    PubMed

    Abedini, Mohammad; Moradi, Mohammad H; Hosseinian, S M

    2016-03-01

    This paper proposes a novel method to address reliability and technical problems of microgrids (MGs) based on designing a number of self-adequate autonomous sub-MGs via adopting MGs clustering thinking. In doing so, a multi-objective optimization problem is developed where power losses reduction, voltage profile improvement and reliability enhancement are considered as the objective functions. To solve the optimization problem a hybrid algorithm, named HS-GA, is provided, based on genetic and harmony search algorithms, and a load flow method is given to model different types of DGs as droop controller. The performance of the proposed method is evaluated in two case studies. The results provide support for the performance of the proposed method. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

  15. Architecture for Knowledge-Based and Federated Search of Online Clinical Evidence

    PubMed Central

    Walther, Martin; Nguyen, Ken; Lovell, Nigel H

    2005-01-01

    Background It is increasingly difficult for clinicians to keep up-to-date with the rapidly growing biomedical literature. Online evidence retrieval methods are now seen as a core tool to support evidence-based health practice. However, standard search engine technology is not designed to manage the many different types of evidence sources that are available or to handle the very different information needs of various clinical groups, who often work in widely different settings. Objectives The objectives of this paper are (1) to describe the design considerations and system architecture of a wrapper-mediator approach to federate search system design, including the use of knowledge-based, meta-search filters, and (2) to analyze the implications of system design choices on performance measurements. Methods A trial was performed to evaluate the technical performance of a federated evidence retrieval system, which provided access to eight distinct online resources, including e-journals, PubMed, and electronic guidelines. The Quick Clinical system architecture utilized a universal query language to reformulate queries internally and utilized meta-search filters to optimize search strategies across resources. We recruited 227 family physicians from across Australia who used the system to retrieve evidence in a routine clinical setting over a 4-week period. The total search time for a query was recorded, along with the duration of individual queries sent to different online resources. Results Clinicians performed 1662 searches over the trial. The average search duration was 4.9 ± 3.2 s (N = 1662 searches). Mean search duration to the individual sources was between 0.05 s and 4.55 s. Average system time (ie, system overhead) was 0.12 s. Conclusions The relatively small system overhead compared to the average time it takes to perform a search for an individual source shows that the system achieves a good trade-off between performance and reliability. Furthermore, despite

  16. Architecture for knowledge-based and federated search of online clinical evidence.

    PubMed

    Coiera, Enrico; Walther, Martin; Nguyen, Ken; Lovell, Nigel H

    2005-10-24

    It is increasingly difficult for clinicians to keep up-to-date with the rapidly growing biomedical literature. Online evidence retrieval methods are now seen as a core tool to support evidence-based health practice. However, standard search engine technology is not designed to manage the many different types of evidence sources that are available or to handle the very different information needs of various clinical groups, who often work in widely different settings. The objectives of this paper are (1) to describe the design considerations and system architecture of a wrapper-mediator approach to federate search system design, including the use of knowledge-based, meta-search filters, and (2) to analyze the implications of system design choices on performance measurements. A trial was performed to evaluate the technical performance of a federated evidence retrieval system, which provided access to eight distinct online resources, including e-journals, PubMed, and electronic guidelines. The Quick Clinical system architecture utilized a universal query language to reformulate queries internally and utilized meta-search filters to optimize search strategies across resources. We recruited 227 family physicians from across Australia who used the system to retrieve evidence in a routine clinical setting over a 4-week period. The total search time for a query was recorded, along with the duration of individual queries sent to different online resources. Clinicians performed 1662 searches over the trial. The average search duration was 4.9 +/- 3.2 s (N = 1662 searches). Mean search duration to the individual sources was between 0.05 s and 4.55 s. Average system time (ie, system overhead) was 0.12 s. The relatively small system overhead compared to the average time it takes to perform a search for an individual source shows that the system achieves a good trade-off between performance and reliability. Furthermore, despite the additional effort required to incorporate the

  17. Library Networks and Electronic Publishing.

    ERIC Educational Resources Information Center

    Olvey, Lee D.

    1995-01-01

    Provides a description of present and proposed plans and strategies of OCLC (Online Computer Library Center) and their relationship to electronic publishing. FirstSearch (end-user access to secondary information), GUIDON (electronic journals online) and FastDoc (document delivery) are emphasized. (JKP)

  18. An ISOCAM based search for brown dwarfs in the Hyades

    NASA Technical Reports Server (NTRS)

    Ali, B.; Forrest, W.; Leggett, S.; Stauffer, J.

    2000-01-01

    Brwon dwarfs in open cluster in general and in Hyades in particular are valuable as the age, distance and chemical composition of these dwarfs are well-constrained. The cooled environment of ISO allowed us to survey the low-mass component of the Hyades cluster with flux sensitivity unavailable from ground-based telescopes.

  19. Work-Based Learning: In Search of an Effective Model

    ERIC Educational Resources Information Center

    Sobiechowska, Paula; Maisch, Maire

    2006-01-01

    This article draws upon 10 years of pedagogic experience in developing and delivering work-based learning programmes within the United Kingdom national social work post-qualifying framework. The article is a retrospective, reflective and thematic account of our work. It briefly outlines the history of post-qualifying social work education and…

  20. An ISOCAM based search for brown dwarfs in the Hyades

    NASA Technical Reports Server (NTRS)

    Ali, B.; Forrest, W.; Leggett, S.; Stauffer, J.

    2000-01-01

    Brwon dwarfs in open cluster in general and in Hyades in particular are valuable as the age, distance and chemical composition of these dwarfs are well-constrained. The cooled environment of ISO allowed us to survey the low-mass component of the Hyades cluster with flux sensitivity unavailable from ground-based telescopes.

  1. MediAgent: a WWW-based scalable and self-learning medical search engine.

    PubMed Central

    Tay, J.; Ke, S.; Lun, K. C.

    1998-01-01

    Searching for medical information on the Internet can be tedious and frustrating due to the number of irrelevant entries returned from generic search engines. We have developed MediAgent, a scalable search engine that aims to deliver a web-based medical search solution which is focused, exhaustive and able to keep improving its databases. The software package can run off a single low-end system and be scaled into a client-server, distributed computing architecture for high-end needs. This scalable architecture boosts MediAgent's handling capacity to tens of millions of web pages. In addition to large volume handling, MediAgent is designed to be manageable. All subsystems are not only highly configurable, but also support remote, interactive management and monitoring by the system administrator. PMID:9929289

  2. A suffix arrays based approach to semantic search in P2P systems

    NASA Astrophysics Data System (ADS)

    Shi, Qingwei; Zhao, Zheng; Bao, Hu

    2007-09-01

    Building a semantic search system on top of peer-to-peer (P2P) networks is becoming an attractive and promising alternative scheme for the reason of scalability, Data freshness and search cost. In this paper, we present a Suffix Arrays based algorithm for Semantic Search (SASS) in P2P systems, which generates a distributed Semantic Overlay Network (SONs) construction for full-text search in P2P networks. For each node through the P2P network, SASS distributes document indices based on a set of suffix arrays, by which clusters are created depending on words or phrases shared between documents, therefore, the search cost for a given query is decreased by only scanning semantically related documents. In contrast to recently announced SONs scheme designed by using metadata or predefined-class, SASS is an unsupervised approach for decentralized generation of SONs. SASS is also an incremental, linear time algorithm, which efficiently handle the problem of nodes update in P2P networks. Our simulation results demonstrate that SASS yields high search efficiency in dynamic environments.

  3. A Semidefinite Programming Based Search Strategy for Feature Selection with Mutual Information Measure.

    PubMed

    Naghibi, Tofigh; Hoffmann, Sarah; Pfister, Beat

    2015-08-01

    Feature subset selection, as a special case of the general subset selection problem, has been the topic of a considerable number of studies due to the growing importance of data-mining applications. In the feature subset selection problem there are two main issues that need to be addressed: (i) Finding an appropriate measure function than can be fairly fast and robustly computed for high-dimensional data. (ii) A search strategy to optimize the measure over the subset space in a reasonable amount of time. In this article mutual information between features and class labels is considered to be the measure function. Two series expansions for mutual information are proposed, and it is shown that most heuristic criteria suggested in the literature are truncated approximations of these expansions. It is well-known that searching the whole subset space is an NP-hard problem. Here, instead of the conventional sequential search algorithms, we suggest a parallel search strategy based on semidefinite programming (SDP) that can search through the subset space in polynomial time. By exploiting the similarities between the proposed algorithm and an instance of the maximum-cut problem in graph theory, the approximation ratio of this algorithm is derived and is compared with the approximation ratio of the backward elimination method. The experiments show that it can be misleading to judge the quality of a measure solely based on the classification accuracy, without taking the effect of the non-optimum search strategy into account.

  4. Comparative Efficiency of Searching Titles, Abstracts, and Index Terms in a Free-Text Data Base

    ERIC Educational Resources Information Center

    And Others; Barker, F. H.

    1972-01-01

    An investigation was made into the relative performance of the four major Chemical Abstracts Service magnetic tape data-bases. The overall retrieval efficiency of profiles searched against data-bases containing titles only, titles-plus-keywords, and titles-plus-digests, was calculated and these results are presented. (5 references) (Author/NH)

  5. Searching the "Nuclear Science Abstracts" Data Base by Use of the Berkeley Mass Storage System

    ERIC Educational Resources Information Center

    Herr, J. Joanne; Smith, Gloria L.

    1972-01-01

    Advantages of the Berkeley Mass Storage System (MSS) for information retrieval other than its size are: high serial-read rate, archival data storage; and random-access capability. By use of this device, the search cost in an SDI system based on the Nuclear Science Abstracts" data base was reduced by 20 percent. (6 references) (Author/NH)

  6. Comparative Efficiency of Searching Titles, Abstracts, and Index Terms in a Free-Text Data Base

    ERIC Educational Resources Information Center

    And Others; Barker, F. H.

    1972-01-01

    An investigation was made into the relative performance of the four major Chemical Abstracts Service magnetic tape data-bases. The overall retrieval efficiency of profiles searched against data-bases containing titles only, titles-plus-keywords, and titles-plus-digests, was calculated and these results are presented. (5 references) (Author/NH)

  7. Ontology-Driven Search and Triage: Design of a Web-Based Visual Interface for MEDLINE.

    PubMed

    Demelo, Jonathan; Parsons, Paul; Sedig, Kamran

    2017-02-02

    Diverse users need to search health and medical literature to satisfy open-ended goals such as making evidence-based decisions and updating their knowledge. However, doing so is challenging due to at least two major difficulties: (1) articulating information needs using accurate vocabulary and (2) dealing with large document sets returned from searches. Common search interfaces such as PubMed do not provide adequate support for exploratory search tasks. Our objective was to improve support for exploratory search tasks by combining two strategies in the design of an interactive visual interface by (1) using a formal ontology to help users build domain-specific knowledge and vocabulary and (2) providing multi-stage triaging support to help mitigate the information overload problem. We developed a Web-based tool, Ontology-Driven Visual Search and Triage Interface for MEDLINE (OVERT-MED), to test our design ideas. We implemented a custom searchable index of MEDLINE, which comprises approximately 25 million document citations. We chose a popular biomedical ontology, the Human Phenotype Ontology (HPO), to test our solution to the vocabulary problem. We implemented multistage triaging support in OVERT-MED, with the aid of interactive visualization techniques, to help users deal with large document sets returned from searches. Formative evaluation suggests that the design features in OVERT-MED are helpful in addressing the two major difficulties described above. Using a formal ontology seems to help users articulate their information needs with more accurate vocabulary. In addition, multistage triaging combined with interactive visualizations shows promise in mitigating the information overload problem. Our strategies appear to be valuable in addressing the two major problems in exploratory search. Although we tested OVERT-MED with a particular ontology and document collection, we anticipate that our strategies can be transferred successfully to other contexts.

  8. Ontology-Driven Search and Triage: Design of a Web-Based Visual Interface for MEDLINE

    PubMed Central

    2017-01-01

    Background Diverse users need to search health and medical literature to satisfy open-ended goals such as making evidence-based decisions and updating their knowledge. However, doing so is challenging due to at least two major difficulties: (1) articulating information needs using accurate vocabulary and (2) dealing with large document sets returned from searches. Common search interfaces such as PubMed do not provide adequate support for exploratory search tasks. Objective Our objective was to improve support for exploratory search tasks by combining two strategies in the design of an interactive visual interface by (1) using a formal ontology to help users build domain-specific knowledge and vocabulary and (2) providing multi-stage triaging support to help mitigate the information overload problem. Methods We developed a Web-based tool, Ontology-Driven Visual Search and Triage Interface for MEDLINE (OVERT-MED), to test our design ideas. We implemented a custom searchable index of MEDLINE, which comprises approximately 25 million document citations. We chose a popular biomedical ontology, the Human Phenotype Ontology (HPO), to test our solution to the vocabulary problem. We implemented multistage triaging support in OVERT-MED, with the aid of interactive visualization techniques, to help users deal with large document sets returned from searches. Results Formative evaluation suggests that the design features in OVERT-MED are helpful in addressing the two major difficulties described above. Using a formal ontology seems to help users articulate their information needs with more accurate vocabulary. In addition, multistage triaging combined with interactive visualizations shows promise in mitigating the information overload problem. Conclusions Our strategies appear to be valuable in addressing the two major problems in exploratory search. Although we tested OVERT-MED with a particular ontology and document collection, we anticipate that our strategies can be

  9. WS-BP: An efficient wolf search based back-propagation algorithm

    NASA Astrophysics Data System (ADS)

    Nawi, Nazri Mohd; Rehman, M. Z.; Khan, Abdullah

    2015-05-01

    Wolf Search (WS) is a heuristic based optimization algorithm. Inspired by the preying and survival capabilities of the wolves, this algorithm is highly capable to search large spaces in the candidate solutions. This paper investigates the use of WS algorithm in combination with back-propagation neural network (BPNN) algorithm to overcome the local minima problem and to improve convergence in gradient descent. The performance of the proposed Wolf Search based Back-Propagation (WS-BP) algorithm is compared with Artificial Bee Colony Back-Propagation (ABC-BP), Bat Based Back-Propagation (Bat-BP), and conventional BPNN algorithms. Specifically, OR and XOR datasets are used for training the network. The simulation results show that the WS-BP algorithm effectively avoids the local minima and converge to global minima.

  10. In search of evidence-based treatment for concussion: characteristics of current clinical trials.

    PubMed

    Burke, Matthew J; Fralick, Michael; Nejatbakhsh, Nasrin; Tartaglia, Maria C; Tator, Charles H

    2015-01-01

    Abstract Objective: To assess the characteristics of current clinical trials investigating the treatment of concussion. Recent systematic literature reviews have concluded that there is minimal evidence to support any specific treatment for concussion, including the principles of return-to-activity protocols such as type or duration of rest. Clinical trial data was extracted from Clinicaltrials.gov and seven additional World Health Organization primary registries. The trial databases were accessed up until 3 October 2013. This study used search terms of 'concussion' or 'mild traumatic brain injury' (mTBI) and filtered for interventional trials. Trials that were terminated, already published or not interventional trials of concussion/mTBI were excluded. Of the 142 concussion/mTBI interventional clinical trials identified, 71 met inclusion criteria. Trials had a median estimated enrolment of 60 participants. There was a wide-range of treatments studied, including cognitive/behavioural therapies (28.2%), medications (28.2%), devices (11.3%), dietary supplements (8.5%), return-to-activity/rest (1.4%) and others (22.4%). Heterogeneity among trials for concussion identification/diagnosis and primary outcomes utilized was evident. Symptom-based questionnaires (39.4%) and neuropsychological tests (28.2%) were the most common outcome measures. Diverse, potentially promising therapeutics are currently being studied for the treatment of concussion. However, several deficiencies were identified including a paucity of trials addressing return-to-activity principles. Also, small sample size and trial heterogeneity may threaten scientific evaluation and subsequent clinical application.

  11. In search of evidence-based treatment for concussion: characteristics of current clinical trials

    PubMed Central

    Burke, Matthew J.; Fralick, Michael; Nejatbakhsh, Nasrin; Tartaglia, Maria C.; Tator, Charles H.

    2015-01-01

    Abstract Objective: To assess the characteristics of current clinical trials investigating the treatment of concussion. Background: Recent systematic literature reviews have concluded that there is minimal evidence to support any specific treatment for concussion, including the principles of return-to-activity protocols such as type or duration of rest. Design/methods: Clinical trial data was extracted from Clinicaltrials.gov and seven additional World Health Organization primary registries. The trial databases were accessed up until 3 October 2013. This study used search terms of ‘concussion’ or ‘mild traumatic brain injury’ (mTBI) and filtered for interventional trials. Trials that were terminated, already published or not interventional trials of concussion/mTBI were excluded. Results: Of the 142 concussion/mTBI interventional clinical trials identified, 71 met inclusion criteria. Trials had a median estimated enrolment of 60 participants. There was a wide-range of treatments studied, including cognitive/behavioural therapies (28.2%), medications (28.2%), devices (11.3%), dietary supplements (8.5%), return-to-activity/rest (1.4%) and others (22.4%). Heterogeneity among trials for concussion identification/diagnosis and primary outcomes utilized was evident. Symptom-based questionnaires (39.4%) and neuropsychological tests (28.2%) were the most common outcome measures. Conclusions: Diverse, potentially promising therapeutics are currently being studied for the treatment of concussion. However, several deficiencies were identified including a paucity of trials addressing return-to-activity principles. Also, small sample size and trial heterogeneity may threaten scientific evaluation and subsequent clinical application. PMID:25383510

  12. Content-based video indexing and searching with wavelet transformation

    NASA Astrophysics Data System (ADS)

    Stumpf, Florian; Al-Jawad, Naseer; Du, Hongbo; Jassim, Sabah

    2006-05-01

    Biometric databases form an essential tool in the fight against international terrorism, organised crime and fraud. Various government and law enforcement agencies have their own biometric databases consisting of combination of fingerprints, Iris codes, face images/videos and speech records for an increasing number of persons. In many cases personal data linked to biometric records are incomplete and/or inaccurate. Besides, biometric data in different databases for the same individual may be recorded with different personal details. Following the recent terrorist atrocities, law enforcing agencies collaborate more than before and have greater reliance on database sharing. In such an environment, reliable biometric-based identification must not only determine who you are but also who else you are. In this paper we propose a compact content-based video signature and indexing scheme that can facilitate retrieval of multiple records in face biometric databases that belong to the same person even if their associated personal data are inconsistent. We shall assess the performance of our system using a benchmark audio visual face biometric database that has multiple videos for each subject but with different identity claims. We shall demonstrate that retrieval of relatively small number of videos that are nearest, in terms of the proposed index, to any video in the database results in significant proportion of that individual biometric data.

  13. Evidence integration in model-based tree search

    PubMed Central

    Solway, Alec; Botvinick, Matthew M.

    2015-01-01

    Research on the dynamics of reward-based, goal-directed decision making has largely focused on simple choice, where participants decide among a set of unitary, mutually exclusive options. Recent work suggests that the deliberation process underlying simple choice can be understood in terms of evidence integration: Noisy evidence in favor of each option accrues over time, until the evidence in favor of one option is significantly greater than the rest. However, real-life decisions often involve not one, but several steps of action, requiring a consideration of cumulative rewards and a sensitivity to recursive decision structure. We present results from two experiments that leveraged techniques previously applied to simple choice to shed light on the deliberation process underlying multistep choice. We interpret the results from these experiments in terms of a new computational model, which extends the evidence accumulation perspective to multiple steps of action. PMID:26324932

  14. Combined string searching algorithm based on knuth-morris- pratt and boyer-moore algorithms

    NASA Astrophysics Data System (ADS)

    Tsarev, R. Yu; Chernigovskiy, A. S.; Tsareva, E. A.; Brezitskaya, V. V.; Nikiforov, A. Yu; Smirnov, N. A.

    2016-04-01

    The string searching task can be classified as a classic information processing task. Users either encounter the solution of this task while working with text processors or browsers, employing standard built-in tools, or this task is solved unseen by the users, while they are working with various computer programmes. Nowadays there are many algorithms for solving the string searching problem. The main criterion of these algorithms’ effectiveness is searching speed. The larger the shift of the pattern relative to the string in case of pattern and string characters’ mismatch is, the higher is the algorithm running speed. This article offers a combined algorithm, which has been developed on the basis of well-known Knuth-Morris-Pratt and Boyer-Moore string searching algorithms. These algorithms are based on two different basic principles of pattern matching. Knuth-Morris-Pratt algorithm is based upon forward pattern matching and Boyer-Moore is based upon backward pattern matching. Having united these two algorithms, the combined algorithm allows acquiring the larger shift in case of pattern and string characters’ mismatch. The article provides an example, which illustrates the results of Boyer-Moore and Knuth-Morris- Pratt algorithms and combined algorithm’s work and shows advantage of the latter in solving string searching problem.

  15. Free Energy-Based Conformational Search Algorithm Using the Movable Type Sampling Method.

    PubMed

    Pan, Li-Li; Zheng, Zheng; Wang, Ting; Merz, Kenneth M

    2015-12-08

    In this article, we extend the movable type (MT) sampling method to molecular conformational searches (MT-CS) on the free energy surface of the molecule in question. Differing from traditional systematic and stochastic searching algorithms, this method uses Boltzmann energy information to facilitate the selection of the best conformations. The generated ensembles provided good coverage of the available conformational space including available crystal structures. Furthermore, our approach directly provides the solvation free energies and the relative gas and aqueous phase free energies for all generated conformers. The method is validated by a thorough analysis of thrombin ligands as well as against structures extracted from both the Protein Data Bank (PDB) and the Cambridge Structural Database (CSD). An in-depth comparison between OMEGA and MT-CS is presented to illustrate the differences between the two conformational searching strategies, i.e., energy-based versus free energy-based searching. These studies demonstrate that our MT-based ligand conformational search algorithm is a powerful approach to delineate the conformational ensembles of molecular species on free energy surfaces.

  16. Multi-AUV Target Search Based on Bioinspired Neurodynamics Model in 3-D Underwater Environments.

    PubMed

    Cao, Xiang; Zhu, Daqi; Yang, Simon X

    2016-11-01

    Target search in 3-D underwater environments is a challenge in multiple autonomous underwater vehicles (multi-AUVs) exploration. This paper focuses on an effective strategy for multi-AUV target search in the 3-D underwater environments with obstacles. First, the Dempster-Shafer theory of evidence is applied to extract information of environment from the sonar data to build a grid map of the underwater environments. Second, a topologically organized bioinspired neurodynamics model based on the grid map is constructed to represent the dynamic environment. The target globally attracts the AUVs through the dynamic neural activity landscape of the model, while the obstacles locally push the AUVs away to avoid collision. Finally, the AUVs plan their search path to the targets autonomously by a steepest gradient descent rule. The proposed algorithm deals with various situations, such as static targets search, dynamic targets search, and one or several AUVs break down in the 3-D underwater environments with obstacles. The simulation results show that the proposed algorithm is capable of guiding multi-AUV to achieve search task of multiple targets with higher efficiency and adaptability compared with other algorithms.

  17. Two-dimensional minimum discontinuity phase unwrapping based on tabu search

    NASA Astrophysics Data System (ADS)

    Lu, Yuangang; Zhang, Ting; Zhang, Xuping

    2008-12-01

    Phase unwrapping is the task of recovering the true phase values, given the wrapped phase values in an image. Flynn's minimum discontinuity phase unwrapping algorithm can deal with many different kinds of phase unwrapping problems successfully. However, since it takes the whole wrapped phase image as the improving loop search areas, Flynn's algorithm has low efficiency in searching for the phase's discontinuity. To overcome this drawback, a new minimum discontinuity phase unwrapping algorithm based on tabu search is proposed in this paper. In the proposed algorithm, the nodes of the wrapped image are divided into different N levels according to the corresponding quality of the wrapped image and the nodes with high levels are added into tabu list. In the iteration process of improving loops search, the tabu list is updated according to the aspiration criterion to allow the search areas extend to nodes with high levels. By this means, it searches the highest probability nodes belonging to paths of improving loops first and the lowest probability nodes last. As a result, it significantly improves the efficiency of the algorithm. The proposed algorithm is described in detail and verified by use of an experimental wrapped phase image with noise and undersampling. Unwrapped results show that the proposed algorithm works well and is more effectively than the Flynn's minimum discontinuity algorithm.

  18. Applying systematic review search methods to the grey literature: a case study examining guidelines for school-based breakfast programs in Canada.

    PubMed

    Godin, Katelyn; Stapleton, Jackie; Kirkpatrick, Sharon I; Hanning, Rhona M; Leatherdale, Scott T

    2015-10-22

    Grey literature is an important source of information for large-scale review syntheses. However, there are many characteristics of grey literature that make it difficult to search systematically. Further, there is no 'gold standard' for rigorous systematic grey literature search methods and few resources on how to conduct this type of search. This paper describes systematic review search methods that were developed and applied to complete a case study systematic review of grey literature that examined guidelines for school-based breakfast programs in Canada. A grey literature search plan was developed to incorporate four different searching strategies: (1) grey literature databases, (2) customized Google search engines, (3) targeted websites, and (4) consultation with contact experts. These complementary strategies were used to minimize the risk of omitting relevant sources. Since abstracts are often unavailable in grey literature documents, items' abstracts, executive summaries, or table of contents (whichever was available) were screened. Screening of publications' full-text followed. Data were extracted on the organization, year published, who they were developed by, intended audience, goal/objectives of document, sources of evidence/resources cited, meals mentioned in the guidelines, and recommendations for program delivery. The search strategies for identifying and screening publications for inclusion in the case study review was found to be manageable, comprehensive, and intuitive when applied in practice. The four search strategies of the grey literature search plan yielded 302 potentially relevant items for screening. Following the screening process, 15 publications that met all eligibility criteria remained and were included in the case study systematic review. The high-level findings of the case study systematic review are briefly described. This article demonstrated a feasible and seemingly robust method for applying systematic search strategies to

  19. A Hybrid Neural Network Model for Sales Forecasting Based on ARIMA and Search Popularity of Article Titles.

    PubMed

    Omar, Hani; Hoang, Van Hai; Liu, Duen-Ren

    2016-01-01

    Enhancing sales and operations planning through forecasting analysis and business intelligence is demanded in many industries and enterprises. Publishing industries usually pick attractive titles and headlines for their stories to increase sales, since popular article titles and headlines can attract readers to buy magazines. In this paper, information retrieval techniques are adopted to extract words from article titles. The popularity measures of article titles are then analyzed by using the search indexes obtained from Google search engine. Backpropagation Neural Networks (BPNNs) have successfully been used to develop prediction models for sales forecasting. In this study, we propose a novel hybrid neural network model for sales forecasting based on the prediction result of time series forecasting and the popularity of article titles. The proposed model uses the historical sales data, popularity of article titles, and the prediction result of a time series, Autoregressive Integrated Moving Average (ARIMA) forecasting method to learn a BPNN-based forecasting model. Our proposed forecasting model is experimentally evaluated by comparing with conventional sales prediction techniques. The experimental result shows that our proposed forecasting method outperforms conventional techniques which do not consider the popularity of title words.

  20. A Hybrid Neural Network Model for Sales Forecasting Based on ARIMA and Search Popularity of Article Titles

    PubMed Central

    Omar, Hani; Hoang, Van Hai; Liu, Duen-Ren

    2016-01-01

    Enhancing sales and operations planning through forecasting analysis and business intelligence is demanded in many industries and enterprises. Publishing industries usually pick attractive titles and headlines for their stories to increase sales, since popular article titles and headlines can attract readers to buy magazines. In this paper, information retrieval techniques are adopted to extract words from article titles. The popularity measures of article titles are then analyzed by using the search indexes obtained from Google search engine. Backpropagation Neural Networks (BPNNs) have successfully been used to develop prediction models for sales forecasting. In this study, we propose a novel hybrid neural network model for sales forecasting based on the prediction result of time series forecasting and the popularity of article titles. The proposed model uses the historical sales data, popularity of article titles, and the prediction result of a time series, Autoregressive Integrated Moving Average (ARIMA) forecasting method to learn a BPNN-based forecasting model. Our proposed forecasting model is experimentally evaluated by comparing with conventional sales prediction techniques. The experimental result shows that our proposed forecasting method outperforms conventional techniques which do not consider the popularity of title words. PMID:27313605

  1. Selective Search and Intensity Context Based Retina Vessel Image Segmentation.

    PubMed

    Tang, Zhaohui; Zhang, Jin; Gui, Weihua

    2017-03-01

    In the framework of computer-aided diagnosis of eye disease, a new contextual image feature named influence degree of average intensity is proposed for retinal vessel image segmentation. This new feature evaluates the influence degree of current detected pixel decreasing the average intensity of the local row where that pixel located. Firstly, Hessian matrix is introduced to detect candidate regions, for the reason of accelerating segmentation. Then, the influence degree of average intensity of each pixel is extracted. Next, contextual feature vector for each pixel is constructed by concatenating the 8 feature neighbors. Finally, a classifier is built to classify each pixel into vessel or non-vessel based on its contextual feature. The effectiveness of the proposed method is demonstrated through receiver operating characteristic analysis on the benchmarked databases of DRIVE and STARE. Experiment results show that our method is comparable with the state-of-the-art methods. For example, the average accuracy, sensitivity, specificity achieved on the database DRIVE and STARE are 0.9611, 0.8174, 0.9747 and 0.9547, 0.7768, 0.9751, respectively.

  2. Computational Search for Novel Hard Chromium-Based Materials.

    PubMed

    Kvashnin, Alexander G; Oganov, Artem R; Samtsevich, Artem I; Allahyari, Zahed

    2017-02-16

    Nitrides, carbides, and borides of transition metals are an attractive class of hard materials. Our recent preliminary explorations of the binary chemical compounds indicated that chromium-based materials are among the hardest transition metal compounds. Motivated by this, here we explore in detail the binary Cr-B, Cr-C, and Cr-N systems using global optimization techniques. Calculated enthalpy of formation and hardness of predicted materials were used for Pareto optimization to define the hardest materials with the lowest energy. Our calculations recover all numerous known stable compounds (except Cr23C6 with its large unit cell) and discover a novel stable phase Pmn21-Cr2C. We resolve the structure of Cr2N and find it to be of anti-CaCl2 type (space group Pnnm). Many of these phases possess remarkable hardness, but only CrB4 is superhard (Vickers hardness 48 GPa). Among chromium compounds, borides generally possess the highest hardnesses and greatest stability. Under pressure, we predict stabilization of a layered TMDC-like phase of Cr2N, a WC-type phase of CrN, and a new compound CrN4. Nitrogen-rich chromium nitride CrN4 is a high-energy-density material featuring polymeric nitrogen chains. In the presence of metal atoms (e.g., Cr), polymerization of nitrogen takes place at much lower pressures; CrN4 becomes stable at ∼15 GPa (cf. 110 GPa for synthesis of pure polymeric nitrogen).

  3. A grammar based methodology for structural motif finding in ncRNA database search.

    PubMed

    Quest, Daniel; Tapprich, William; Ali, Hesham

    2007-01-01

    In recent years, sequence database searching has been conducted through local alignment heuristics, pattern-matching, and comparison of short statistically significant patterns. While these approaches have unlocked many clues as to sequence relationships, they are limited in that they do not provide context-sensitive searching capabilities (e.g. considering pseudoknots, protein binding positions, and complementary base pairs). Stochastic grammars (hidden Markov models HMMs and stochastic context-free grammars SCFG) do allow for flexibility in terms of local context, but the context comes at the cost of increased computational complexity. In this paper we introduce a new grammar based method for searching for RNA motifs that exist within a conserved RNA structure. Our method constrains computational complexity by using a chain of topology elements. Through the use of a case study we present the algorithmic approach and benchmark our approach against traditional methods.

  4. Index-Based Searching of Interaction Patterns in Large Collections of Protein-Ligand Interfaces.

    PubMed

    Inhester, Therese; Bietz, Stefan; Hilbig, Matthias; Schmidt, Robert; Rarey, Matthias

    2017-02-27

    Comparison of three-dimensional interaction patterns in large collections of protein-ligand interfaces is a key element for understanding protein-ligand interactions and supports various steps in the structure-based drug design process. Different methods exist that provide query systems to search for geometrical patterns in protein-ligand complexes. However, these tools do not meet all of the requirements, which are high query variability, an adjustable search set, and high retrieval speed. Here we present a new tool named PELIKAN that is able to search for a variety of geometrical queries in large protein structure collections in a reasonably short time. The data are stored in an SQLite database that can easily be constructed from any set of protein-ligand complexes. We present different test queries demonstrating the performance of the PELIKAN approach. Furthermore, two application scenarios show the usefulness of PELIKAN in structure-based design endeavors.

  5. A comparison of field-based similarity searching methods: CatShape, FBSS, and ROCS.

    PubMed

    Moffat, Kirstin; Gillet, Valerie J; Whittle, Martin; Bravi, Gianpaolo; Leach, Andrew R

    2008-04-01

    Three field-based similarity methods are compared in retrospective virtual screening experiments. The methods are the CatShape module of CATALYST, ROCS, and an in-house program developed at the University of Sheffield called FBSS. The programs are used in both rigid and flexible searches carried out in the MDL Drug Data Report. UNITY 2D fingerprints are also used to provide a comparison with a more traditional approach to similarity searching, and similarity based on simple whole-molecule properties is used to provide a baseline for the more sophisticated searches. Overall, UNITY 2D fingerprints and ROCS with the chemical force field option gave comparable performance and were superior to the shape-only 3D methods. When the flexible methods were compared with the rigid methods, it was generally found that the flexible methods gave slightly better results than their respective rigid methods; however, the increased performance did not justify the additional computational cost required.

  6. Efficiency image data retrieval based on asynchronous capability aware spatial search service middleware

    NASA Astrophysics Data System (ADS)

    Chen, Nengcheng; Chen, Zeqiang; Gong, Jianya

    2007-11-01

    Recent advances in open geospatial web service, such as Web Coverage Service as well as corresponding web ready data processing service, have led to the generation of large amounts of OGC enabled links on Internet. Recently a few search engines that are specialised with respect to geographic space have appeared. However, users do not always get the effective OGC WCS link information they expect when searching the Web. How to quickly find the correct spatial aware web service in a heterogeneous distributed environment has become a "bottleneck" of geospatial web-based applications. In order to improve the retrieval efficiency of OGC Web Coverage Service (WCS) on WWW, a new methodology for retrieving WCS based on clustering capability aware spatial search service middleware is put forward in this paper.

  7. Illustrated Storybooks for Preschool Children Published in Turkey between 1980-2013: A Study Based on Preschool Education Reforms

    ERIC Educational Resources Information Center

    Isitan, Sonnur

    2016-01-01

    The purpose of this study was to examine the distribution of topics featured in illustrated storybooks that address preschool children. The sample of the current study included a total of 1,050 illustrated storybooks published in Turkish between 1980 and 2013. Books for pre-school children that incorporated the components of setting, attempt, and…

  8. Developing Chinese Scientists' Skills for Publishing in English: Evaluating Collaborating-Colleague Workshops Based on Genre Analysis

    ERIC Educational Resources Information Center

    Cargill, Margaret; O'Connor, Patrick

    2006-01-01

    Getting papers published in the (largely English-language) international literature is important for individual researchers, their institutions, and the academic community, and the resulting pressure is being felt increasingly in China as a result of top-down policy initiatives. For many researchers, reaching this goal involves two intersecting…

  9. Inquiry-Based Research Published in "I Wonder: The Journal for Elementary School Scientists" (1992-2000).

    ERIC Educational Resources Information Center

    Beeth, Michael E.; Huziak, Tracy

    Scientific inquiry has been stressed as necessary for all students in science education reform efforts. "I Wonder: The Journal for Elementary School Scientists" provides a unique opportunity for elementary school students to disseminate their scientific investigations in the analog form of print journals. The Heron Network has published this…

  10. Developing Chinese Scientists' Skills for Publishing in English: Evaluating Collaborating-Colleague Workshops Based on Genre Analysis

    ERIC Educational Resources Information Center

    Cargill, Margaret; O'Connor, Patrick

    2006-01-01

    Getting papers published in the (largely English-language) international literature is important for individual researchers, their institutions, and the academic community, and the resulting pressure is being felt increasingly in China as a result of top-down policy initiatives. For many researchers, reaching this goal involves two intersecting…

  11. Cancer-related search for meaning increases willingness to participate in Mindfulness-Based Stress Reduction

    PubMed Central

    Garland, Sheila N.; Stainken, Cameron; Ahluwalia, Karan; Vapiwala, Neha; Mao, Jun J.

    2015-01-01

    Objective A cancer diagnosis can prompt an examination and reevaluation of life’s meaning, purpose, and priorities. There is evidence that Mindfulness-Based Stress Reduction (MBSR) may help facilitate the meaning-making process. This study examined the influence of meaning in life on willingness to participate (WTP) in MBSR and identified factors associated with the search for and/or presence of meaning. Methods A cross-sectional survey study of 300 patients undergoing radiation therapy was conducted. WTP in MBSR was dichotomized into yes/no by asking: “Would you participate in an MBSR program if it was offered at the cancer center?” The search for, and the presence of, meaning were assessed using the Meaning in Life Questionnaire. Results Eighty patients (27%) indicated WTP in MBSR. In a multivariate logistic regression model, search for meaning was the only significant predictor of WTP in MBSR [AOR=1.04, p=<0.001, CI=1.01–1.08]. Identifying as non-white (Adj β = 4.62; 95% CI, 2.22 to 7.02; p < .001), and reporting subclinical (Adj β = 3.59; 95% CI, 0.84 to 6.34; p = .01) or clinical levels (Adj β = 5.52; 95% CI, 2.41 to 8.63; p = .001) of anxiety were the strongest predictors of search for meaning. Conclusion Our study indicates that patients searching for meaning are receptive to MBSR. Nonwhite patients and those experiencing high levels of anxiety are most likely to endorse a search for meaning. Future research is needed to understand how best to support patients who are searching for meaning and remove barriers to evidence-based programs like MBSR. PMID:25870034

  12. Exploring conformational search protocols for ligand-based virtual screening and 3-D QSAR modeling

    NASA Astrophysics Data System (ADS)

    Cappel, Daniel; Dixon, Steven L.; Sherman, Woody; Duan, Jianxin

    2015-02-01

    3-D ligand conformations are required for most ligand-based drug design methods, such as pharmacophore modeling, shape-based screening, and 3-D QSAR model building. Many studies of conformational search methods have focused on the reproduction of crystal structures (i.e. bioactive conformations); however, for ligand-based modeling the key question is how to generate a ligand alignment that produces the best results for a given query molecule. In this work, we study different conformation generation modes of ConfGen and the impact on virtual screening (Shape Screening and e-Pharmacophore) and QSAR predictions (atom-based and field-based). In addition, we develop a new search method, called common scaffold alignment, that automatically detects the maximum common scaffold between each screening molecule and the query to ensure identical coordinates of the common core, thereby minimizing the noise introduced by analogous parts of the molecules. In general, we find that virtual screening results are relatively insensitive to the conformational search protocol; hence, a conformational search method that generates fewer conformations could be considered "better" because it is more computationally efficient for screening. However, for 3-D QSAR modeling we find that more thorough conformational sampling tends to produce better QSAR predictions. In addition, significant improvements in QSAR predictions are obtained with the common scaffold alignment protocol developed in this work, which focuses conformational sampling on parts of the molecules that are not part of the common scaffold.

  13. Development of an item bank for food parenting practices based on published instruments and reports from Canadian and US parents.

    PubMed

    O'Connor, Teresia M; Pham, Truc; Watts, Allison W; Tu, Andrew W; Hughes, Sheryl O; Beauchamp, Mark R; Baranowski, Tom; Mâsse, Louise C

    2016-08-01

    Research to understand how parents influence their children's dietary intake and eating behaviors has expanded in the past decades and a growing number of instruments are available to assess food parenting practices. Unfortunately, there is no consensus on how constructs should be defined or operationalized, making comparison of results across studies difficult. The aim of this study was to develop a food parenting practice item bank with items from published scales and supplement with parenting practices that parents report using. Items from published scales were identified from two published systematic reviews along with an additional systematic review conducted for this study. Parents (n = 135) with children 5-12 years old from the US and Canada, stratified to represent the demographic distribution of each country, were recruited to participate in an online semi-qualitative survey on food parenting. Published items and parent responses were coded using the same framework to reduce the number of items into representative concepts using a binning and winnowing process. The literature contributed 1392 items and parents contributed 1985 items, which were reduced to 262 different food parenting concepts (26% exclusive from literature, 12% exclusive from parents, and 62% represented in both). Food parenting practices related to 'Structure of Food Environment' and 'Behavioral and Educational' were emphasized more by parent responses, while practices related to 'Consistency of Feeding Environment' and 'Emotional Regulation' were more represented among published items. The resulting food parenting item bank should next be calibrated with item response modeling for scientists to use in the future. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. A lightning-based search for nearby observationally dim terrestrial gamma ray flashes

    NASA Astrophysics Data System (ADS)

    McTague, L. E.; Cummer, S. A.; Briggs, M. S.; Connaughton, V.; Stanbro, M.; Fitzpatrick, G.

    2015-12-01

    Current space-based observations of terrestrial gamma ray flashes (TGFs) are capable of identifying only TGFs that exceed a lower brightness threshold. Observationally, dim TGFs that fall below this threshold are consequently difficult to find using photon-only search algorithms. Such TGFs are a potentially important part of the overall global TGF rate, and information on their occurrence rate would give important insight into TGF generation mechanisms. We describe and implement a lightning-based search for TGFs that uses the location and time of National Lightning Detection Network reported positive polarity, in-cloud (+IC) discharges of the type known to be directly associated with TGFs. These events identify a 200 μs search window when any associated TGF photons would have been detected. We show that this approach can detect TGFs without requiring a lower threshold on the detected photon brightness of the event, and thus is capable, in principle, of finding a population of weak TGFs. We find that TGFs occur at a rate between 1 in 40 and 1 in 500 of in-cloud lightning events that meet our study's criteria. The distribution of gamma ray counts in the search windows exhibits a statistically significant lack of nearby dim TGFs below the GBM search threshold. The data favor a brightness distribution in which nearby observationally dim TGFs are rare.

  15. A semantics-based method for clustering of Chinese web search results

    NASA Astrophysics Data System (ADS)

    Zhang, Hui; Wang, Deqing; Wang, Li; Bi, Zhuming; Chen, Yong

    2014-01-01

    Information explosion is a critical challenge to the development of modern information systems. In particular, when the application of an information system is over the Internet, the amount of information over the web has been increasing exponentially and rapidly. Search engines, such as Google and Baidu, are essential tools for people to find the information from the Internet. Valuable information, however, is still likely submerged in the ocean of search results from those tools. By clustering the results into different groups based on subjects automatically, a search engine with the clustering feature allows users to select most relevant results quickly. In this paper, we propose an online semantics-based method to cluster Chinese web search results. First, we employ the generalised suffix tree to extract the longest common substrings (LCSs) from search snippets. Second, we use the HowNet to calculate the similarities of the words derived from the LCSs, and extract the most representative features by constructing the vocabulary chain. Third, we construct a vector of text features and calculate snippets' semantic similarities. Finally, we improve the Chameleon algorithm to cluster snippets. Extensive experimental results have shown that the proposed algorithm has outperformed over the suffix tree clustering method and other traditional clustering methods.

  16. Exploring personalized searches using tag-based user profiles and resource profiles in folksonomy.

    PubMed

    Cai, Yi; Li, Qing; Xie, Haoran; Min, Huaqin

    2014-10-01

    With the increase in resource-sharing websites such as YouTube and Flickr, many shared resources have arisen on the Web. Personalized searches have become more important and challenging since users demand higher retrieval quality. To achieve this goal, personalized searches need to take users' personalized profiles and information needs into consideration. Collaborative tagging (also known as folksonomy) systems allow users to annotate resources with their own tags, which provides a simple but powerful way for organizing, retrieving and sharing different types of social resources. In this article, we examine the limitations of previous tag-based personalized searches. To handle these limitations, we propose a new method to model user profiles and resource profiles in collaborative tagging systems. We use a normalized term frequency to indicate the preference degree of a user on a tag. A novel search method using such profiles of users and resources is proposed to facilitate the desired personalization in resource searches. In our framework, instead of the keyword matching or similarity measurement used in previous works, the relevance measurement between a resource and a user query (termed the query relevance) is treated as a fuzzy satisfaction problem of a user's query requirements. We implement a prototype system called the Folksonomy-based Multimedia Retrieval System (FMRS). Experiments using the FMRS data set and the MovieLens data set show that our proposed method outperforms baseline methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Web-Based Search and Plot System for Nuclear Reaction Data

    SciTech Connect

    Otuka, N.; Nakagawa, T.; Fukahori, T.; Katakura, J.; Aikawa, M.; Suda, T.; Naito, K.; Korennov, S.; Arai, K.; Noto, H.; Ohnishi, A.; Kato, K.

    2005-05-24

    A web-based search and plot system for nuclear reaction data has been developed, covering experimental data in EXFOR format and evaluated data in ENDF format. The system is implemented for Linux OS, with Perl and MySQL used for CGI scripts and the database manager, respectively. Two prototypes for experimental and evaluated data are presented.

  18. ELE: An Ontology-Based System Integrating Semantic Search and E-Learning Technologies

    ERIC Educational Resources Information Center

    Barbagallo, A.; Formica, A.

    2017-01-01

    ELSE (E-Learning for the Semantic ECM) is an ontology-based system which integrates semantic search methodologies and e-learning technologies. It has been developed within a project of the CME (Continuing Medical Education) program--ECM (Educazione Continua nella Medicina) for Italian participants. ELSE allows the creation of e-learning courses…

  19. Exploring Gender Differences in SMS-Based Mobile Library Search System Adoption

    ERIC Educational Resources Information Center

    Goh, Tiong-Thye

    2011-01-01

    This paper investigates differences in how male and female students perceived a short message service (SMS) library catalog search service when adopting it. Based on a sample of 90 students, the results suggest that there are significant differences in perceived usefulness and intention to use but no significant differences in self-efficacy and…

  20. Information Commitments: Evaluative Standards and Information Searching Strategies in Web-Based Learning Environments

    ERIC Educational Resources Information Center

    Wu, Ying-Tien; Tsai, Chin-Chung

    2005-01-01

    "Information commitments" include both a set of evaluative standards that Web users utilize to assess the accuracy and usefulness of information in Web-based learning environments (implicit component), and the information searching strategies that Web users use on the Internet (explicit component). An "Information Commitment…

  1. EARS: An Online Bibliographic Search and Retrieval System Based on Ordered Explosion.

    ERIC Educational Resources Information Center

    Ramesh, R.; Drury, Colin G.

    1987-01-01

    Provides overview of Ergonomics Abstracts Retrieval System (EARS), an online bibliographic search and retrieval system in the area of human factors engineering. Other online systems are described, the design of EARS based on inverted file organization is explained, and system expansions including a thesaurus are discussed. (Author/LRW)

  2. EARS: An Online Bibliographic Search and Retrieval System Based on Ordered Explosion.

    ERIC Educational Resources Information Center

    Ramesh, R.; Drury, Colin G.

    1987-01-01

    Provides overview of Ergonomics Abstracts Retrieval System (EARS), an online bibliographic search and retrieval system in the area of human factors engineering. Other online systems are described, the design of EARS based on inverted file organization is explained, and system expansions including a thesaurus are discussed. (Author/LRW)

  3. Parallel content-based sub-image retrieval using hierarchical searching

    PubMed Central

    Yang, Lin; Qi, Xin; Xing, Fuyong; Kurc, Tahsin; Saltz, Joel; Foran, David J.

    2014-01-01

    Motivation: The capacity to systematically search through large image collections and ensembles and detect regions exhibiting similar morphological characteristics is central to pathology diagnosis. Unfortunately, the primary methods used to search digitized, whole-slide histopathology specimens are slow and prone to inter- and intra-observer variability. The central objective of this research was to design, develop, and evaluate a content-based image retrieval system to assist doctors for quick and reliable content-based comparative search of similar prostate image patches. Method: Given a representative image patch (sub-image), the algorithm will return a ranked ensemble of image patches throughout the entire whole-slide histology section which exhibits the most similar morphologic characteristics. This is accomplished by first performing hierarchical searching based on a newly developed hierarchical annular histogram (HAH). The set of candidates is then further refined in the second stage of processing by computing a color histogram from eight equally divided segments within each square annular bin defined in the original HAH. A demand-driven master-worker parallelization approach is employed to speed up the searching procedure. Using this strategy, the query patch is broadcasted to all worker processes. Each worker process is dynamically assigned an image by the master process to search for and return a ranked list of similar patches in the image. Results: The algorithm was tested using digitized hematoxylin and eosin (H&E) stained prostate cancer specimens. We have achieved an excellent image retrieval performance. The recall rate within the first 40 rank retrieved image patches is ∼90%. Availability and implementation: Both the testing data and source code can be downloaded from http://pleiad.umdnj.edu/CBII/Bioinformatics/. Contact: lin.yang@uky.edu PMID:24215030

  4. MotionExplorer: exploratory search in human motion capture data based on hierarchical aggregation.

    PubMed

    Bernard, Jürgen; Wilhelm, Nils; Krüger, Björn; May, Thorsten; Schreck, Tobias; Kohlhammer, Jörn

    2013-12-01

    We present MotionExplorer, an exploratory search and analysis system for sequences of human motion in large motion capture data collections. This special type of multivariate time series data is relevant in many research fields including medicine, sports and animation. Key tasks in working with motion data include analysis of motion states and transitions, and synthesis of motion vectors by interpolation and combination. In the practice of research and application of human motion data, challenges exist in providing visual summaries and drill-down functionality for handling large motion data collections. We find that this domain can benefit from appropriate visual retrieval and analysis support to handle these tasks in presence of large motion data. To address this need, we developed MotionExplorer together with domain experts as an exploratory search system based on interactive aggregation and visualization of motion states as a basis for data navigation, exploration, and search. Based on an overview-first type visualization, users are able to search for interesting sub-sequences of motion based on a query-by-example metaphor, and explore search results by details on demand. We developed MotionExplorer in close collaboration with the targeted users who are researchers working on human motion synthesis and analysis, including a summative field study. Additionally, we conducted a laboratory design study to substantially improve MotionExplorer towards an intuitive, usable and robust design. MotionExplorer enables the search in human motion capture data with only a few mouse clicks. The researchers unanimously confirm that the system can efficiently support their work.

  5. Instance-based attention: where could humans look first when searching for an object instance.

    PubMed

    Gao, Changxin; Sang, Nong; Huang, Rui

    2012-01-01

    We present an instance-based attention model to predict where humans could look first when searching for an object instance, and we show its application in image synthesis. The proposed model learns configurational rules from vast scene images described by global scene representations. The rules are then used to predict the focus of attention for the purpose of searching for a given object instance with special scale and pose. Finally, the image synthesis results are obtained by putting the object instance into the scene at the position that attracts most attention. Promising experimental results demonstrate the effectiveness of the proposed model.

  6. Multiparty controlled quantum secure direct communication based on quantum search algorithm

    NASA Astrophysics Data System (ADS)

    Kao, Shih-Hung; Hwang, Tzonelih

    2013-12-01

    In this study, a new controlled quantum secure direct communication (CQSDC) protocol using the quantum search algorithm as the encoding function is proposed. The proposed protocol is based on the multi-particle Greenberger-Horne-Zeilinger entangled state and the one-step quantum transmission strategy. Due to the one-step transmission of qubits, the proposed protocol can be easily extended to a multi-controller environment, and is also free from the Trojan horse attacks. The analysis shows that the use of quantum search algorithm in the construction of CQSDC appears very promising.

  7. A Particle Swarm Optimization-Based Approach with Local Search for Predicting Protein Folding.

    PubMed

    Yang, Cheng-Hong; Lin, Yu-Shiun; Chuang, Li-Yeh; Chang, Hsueh-Wei

    2017-10-01

    The hydrophobic-polar (HP) model is commonly used for predicting protein folding structures and hydrophobic interactions. This study developed a particle swarm optimization (PSO)-based algorithm combined with local search algorithms; specifically, the high exploration PSO (HEPSO) algorithm (which can execute global search processes) was combined with three local search algorithms (hill-climbing algorithm, greedy algorithm, and Tabu table), yielding the proposed HE-L-PSO algorithm. By using 20 known protein structures, we evaluated the performance of the HE-L-PSO algorithm in predicting protein folding in the HP model. The proposed HE-L-PSO algorithm exhibited favorable performance in predicting both short and long amino acid sequences with high reproducibility and stability, compared with seven reported algorithms. The HE-L-PSO algorithm yielded optimal solutions for all predicted protein folding structures. All HE-L-PSO-predicted protein folding structures possessed a hydrophobic core that is similar to normal protein folding.

  8. Differential Evolution Based Intelligent System State Search Method for Composite Power System Reliability Evaluation

    NASA Astrophysics Data System (ADS)

    Bakkiyaraj, Ashok; Kumarappan, N.

    2015-09-01

    This paper presents a new approach for evaluating the reliability indices of a composite power system that adopts binary differential evolution (BDE) algorithm in the search mechanism to select the system states. These states also called dominant states, have large state probability and higher loss of load curtailment necessary to maintain real power balance. A chromosome of a BDE algorithm represents the system state. BDE is not applied for its traditional application of optimizing a non-linear objective function, but used as tool for exploring more number of dominant states by producing new chromosomes, mutant vectors and trail vectors based on the fitness function. The searched system states are used to evaluate annualized system and load point reliability indices. The proposed search methodology is applied to RBTS and IEEE-RTS test systems and results are compared with other approaches. This approach evaluates the indices similar to existing methods while analyzing less number of system states.

  9. Feature selection method based on multi-fractal dimension and harmony search algorithm and its application

    NASA Astrophysics Data System (ADS)

    Zhang, Chen; Ni, Zhiwei; Ni, Liping; Tang, Na

    2016-10-01

    Feature selection is an important method of data preprocessing in data mining. In this paper, a novel feature selection method based on multi-fractal dimension and harmony search algorithm is proposed. Multi-fractal dimension is adopted as the evaluation criterion of feature subset, which can determine the number of selected features. An improved harmony search algorithm is used as the search strategy to improve the efficiency of feature selection. The performance of the proposed method is compared with that of other feature selection algorithms on UCI data-sets. Besides, the proposed method is also used to predict the daily average concentration of PM2.5 in China. Experimental results show that the proposed method can obtain competitive results in terms of both prediction accuracy and the number of selected features.

  10. Three hybridization models based on local search scheme for job shop scheduling problem

    NASA Astrophysics Data System (ADS)

    Balbi Fraga, Tatiana

    2015-05-01

    This work presents three different hybridization models based on the general schema of Local Search Heuristics, named Hybrid Successive Application, Hybrid Neighborhood, and Hybrid Improved Neighborhood. Despite similar approaches might have already been presented in the literature in other contexts, in this work these models are applied to analyzes the solution of the job shop scheduling problem, with the heuristics Taboo Search and Particle Swarm Optimization. Besides, we investigate some aspects that must be considered in order to achieve better solutions than those obtained by the original heuristics. The results demonstrate that the algorithms derived from these three hybrid models are more robust than the original algorithms and able to get better results than those found by the single Taboo Search.

  11. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic

    PubMed Central

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals. PMID:27413364

  12. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic.

    PubMed

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals.

  13. An alphabetic code based atomic level molecular similarity search in databases.

    PubMed

    Saranya, Nallusamy; Selvaraj, Samuel

    2012-01-01

    Atomic level molecular similarity and diversity studies have gained considerable importance through their wide application in Bioinformatics and Chemo-informatics for drug design. The availability of large volumes of data on chemical compounds requires new methodologies for efficient and effective searching of its archives in less time with optimal computational power. We describe an alphabetic algorithm for similarity searching based on atom-atom bonding preference for ligands. We represented 170 cyclindependent kinase 2 inhibitors using strings of pre-defined alphabets for searching using known protein sequence alignment tools. Thus, a common pattern was extracted using this set of compounds for database searching to retrieve similar active compounds. Area under the receiver operating characteristic (ROC) curve was used for the discrimination of similar and dissimilar compounds in the databases. An average retrieval rate of about 60% is obtained in cross-validation using the home-grown dataset and the directory of useful decoys (DUD, formally known as the ZINC database) data. This will help in the effective retrieval of similar compounds using database search.

  14. A novel artificial bee colony algorithm based on modified search equation and orthogonal learning.

    PubMed

    Gao, Wei-feng; Liu, San-yang; Huang, Ling-ling

    2013-06-01

    The artificial bee colony (ABC) algorithm is a relatively new optimization technique which has been shown to be competitive to other population-based algorithms. However, ABC has an insufficiency regarding its solution search equation, which is good at exploration but poor at exploitation. To address this concerning issue, we first propose an improved ABC method called as CABC where a modified search equation is applied to generate a candidate solution to improve the search ability of ABC. Furthermore, we use the orthogonal experimental design (OED) to form an orthogonal learning (OL) strategy for variant ABCs to discover more useful information from the search experiences. Owing to OED's good character of sampling a small number of well representative combinations for testing, the OL strategy can construct a more promising and efficient candidate solution. In this paper, the OL strategy is applied to three versions of ABC, i.e., the standard ABC, global-best-guided ABC (GABC), and CABC, which yields OABC, OGABC, and OCABC, respectively. The experimental results on a set of 22 benchmark functions demonstrate the effectiveness and efficiency of the modified search equation and the OL strategy. The comparisons with some other ABCs and several state-of-the-art algorithms show that the proposed algorithms significantly improve the performance of ABC. Moreover, OCABC offers the highest solution quality, fastest global convergence, and strongest robustness among all the contenders on almost all the test functions.

  15. Hierarchical content-based image retrieval by dynamic indexing and guided search

    NASA Astrophysics Data System (ADS)

    You, Jane; Cheung, King H.; Liu, James; Guo, Linong

    2003-12-01

    This paper presents a new approach to content-based image retrieval by using dynamic indexing and guided search in a hierarchical structure, and extending data mining and data warehousing techniques. The proposed algorithms include: a wavelet-based scheme for multiple image feature extraction, the extension of a conventional data warehouse and an image database to an image data warehouse for dynamic image indexing, an image data schema for hierarchical image representation and dynamic image indexing, a statistically based feature selection scheme to achieve flexible similarity measures, and a feature component code to facilitate query processing and guide the search for the best matching. A series of case studies are reported, which include a wavelet-based image color hierarchy, classification of satellite images, tropical cyclone pattern recognition, and personal identification using multi-level palmprint and face features.

  16. Efficient and Accurate Optimal Linear Phase FIR Filter Design Using Opposition-Based Harmony Search Algorithm

    PubMed Central

    Saha, S. K.; Dutta, R.; Choudhury, R.; Kar, R.; Mandal, D.; Ghoshal, S. P.

    2013-01-01

    In this paper, opposition-based harmony search has been applied for the optimal design of linear phase FIR filters. RGA, PSO, and DE have also been adopted for the sake of comparison. The original harmony search algorithm is chosen as the parent one, and opposition-based approach is applied. During the initialization, randomly generated population of solutions is chosen, opposite solutions are also considered, and the fitter one is selected as a priori guess. In harmony memory, each such solution passes through memory consideration rule, pitch adjustment rule, and then opposition-based reinitialization generation jumping, which gives the optimum result corresponding to the least error fitness in multidimensional search space of FIR filter design. Incorporation of different control parameters in the basic HS algorithm results in the balancing of exploration and exploitation of search space. Low pass, high pass, band pass, and band stop FIR filters are designed with the proposed OHS and other aforementioned algorithms individually for comparative optimization performance. A comparison of simulation results reveals the optimization efficacy of the OHS over the other optimization techniques for the solution of the multimodal, nondifferentiable, nonlinear, and constrained FIR filter design problems. PMID:23844390

  17. Efficient and accurate optimal linear phase FIR filter design using opposition-based harmony search algorithm.

    PubMed

    Saha, S K; Dutta, R; Choudhury, R; Kar, R; Mandal, D; Ghoshal, S P

    2013-01-01

    In this paper, opposition-based harmony search has been applied for the optimal design of linear phase FIR filters. RGA, PSO, and DE have also been adopted for the sake of comparison. The original harmony search algorithm is chosen as the parent one, and opposition-based approach is applied. During the initialization, randomly generated population of solutions is chosen, opposite solutions are also considered, and the fitter one is selected as a priori guess. In harmony memory, each such solution passes through memory consideration rule, pitch adjustment rule, and then opposition-based reinitialization generation jumping, which gives the optimum result corresponding to the least error fitness in multidimensional search space of FIR filter design. Incorporation of different control parameters in the basic HS algorithm results in the balancing of exploration and exploitation of search space. Low pass, high pass, band pass, and band stop FIR filters are designed with the proposed OHS and other aforementioned algorithms individually for comparative optimization performance. A comparison of simulation results reveals the optimization efficacy of the OHS over the other optimization techniques for the solution of the multimodal, nondifferentiable, nonlinear, and constrained FIR filter design problems.

  18. Evaluation of Diffusion-Tensor Imaging-Based Global Search and Tractography for Tumor Surgery Close to the Language System

    PubMed Central

    Richter, Mirco; Zolal, Amir; Ganslandt, Oliver; Buchfelder, Michael; Nimsky, Christopher; Merhof, Dorit

    2013-01-01

    Pre-operative planning and intra-operative guidance in neurosurgery require detailed information about the location of functional areas and their anatomo-functional connectivity. In particular, regarding the language system, post-operative deficits such as aphasia can be avoided. By combining functional magnetic resonance imaging and diffusion tensor imaging, the connectivity between functional areas can be reconstructed by tractography techniques that need to cope with limitations such as limited resolution and low anisotropic diffusion close to functional areas. Tumors pose particular challenges because of edema, displacement effects on brain tissue and infiltration of white matter. Under these conditions, standard fiber tracking methods reconstruct pathways of insufficient quality. Therefore, robust global or probabilistic approaches are required. In this study, two commonly used standard fiber tracking algorithms, streamline propagation and tensor deflection, were compared with a previously published global search, Gibbs tracking and a connection-oriented probabilistic tractography approach. All methods were applied to reconstruct neuronal pathways of the language system of patients undergoing brain tumor surgery, and control subjects. Connections between Broca and Wernicke areas via the arcuate fasciculus (AF) and the inferior fronto-occipital fasciculus (IFOF) were validated by a clinical expert to ensure anatomical feasibility, and compared using distance- and diffusion-based similarity metrics to evaluate their agreement on pathway locations. For both patients and controls, a strong agreement between all methods was observed regarding the location of the AF. In case of the IFOF however, standard fiber tracking and Gibbs tracking predominantly identified the inferior longitudinal fasciculus that plays a secondary role in semantic language processing. In contrast, global search resolved connections in almost every case via the IFOF which could be confirmed by

  19. Web Image Search Re-ranking with Click-based Similarity and Typicality.

    PubMed

    Yang, Xiaopeng; Mei, Tao; Zhang, Yong Dong; Liu, Jie; Satoh, Shin'ichi

    2016-07-20

    In image search re-ranking, besides the well known semantic gap, intent gap, which is the gap between the representation of users' query/demand and the real intent of the users, is becoming a major problem restricting the development of image retrieval. To reduce human effects, in this paper, we use image click-through data, which can be viewed as the "implicit feedback" from users, to help overcome the intention gap, and further improve the image search performance. Generally, the hypothesis visually similar images should be close in a ranking list and the strategy images with higher relevance should be ranked higher than others are widely accepted. To obtain satisfying search results, thus, image similarity and the level of relevance typicality are determinate factors correspondingly. However, when measuring image similarity and typicality, conventional re-ranking approaches only consider visual information and initial ranks of images, while overlooking the influence of click-through data. This paper presents a novel re-ranking approach, named spectral clustering re-ranking with click-based similarity and typicality (SCCST). First, to learn an appropriate similarity measurement, we propose click-based multi-feature similarity learning algorithm (CMSL), which conducts metric learning based on clickbased triplets selection, and integrates multiple features into a unified similarity space via multiple kernel learning. Then based on the learnt click-based image similarity measure, we conduct spectral clustering to group visually and semantically similar images into same clusters, and get the final re-rank list by calculating click-based clusters typicality and withinclusters click-based image typicality in descending order. Our experiments conducted on two real-world query-image datasets with diverse representative queries show that our proposed reranking approach can significantly improve initial search results, and outperform several existing re-ranking approaches.

  20. Threshold dose for peanut: risk characterization based upon published results from challenges of peanut-allergic individuals.

    PubMed

    Taylor, Steve L; Crevel, Rene W R; Sheffield, David; Kabourek, Jamie; Baumert, Joseph

    2009-06-01

    Population thresholds for peanut are unknown. However, lowest- and no-observed adverse effect levels (LOAELs and NOAELs) are published for an unknown number of peanut-allergic individuals. Publications were screened for LOAELs and NOAELs from blinded, low-dose oral challenges. Data were obtained from 185 peanut-allergic individuals (12 publications). Data were analyzed by interval-censoring survival analysis and three probability distribution models fitted to it (Log-Normal, Log-Logistic, and Weibull) to estimate the ED(10). All three models described the data well and provided ED(10)'s in close agreement: 17.6, 17.0, and 14.6 mg of whole peanut for the Log-Normal, Log-Logistic, and Weibull models, respectively. The 95% lower confidence intervals for the ED(10)'s were 9.2, 8.1, and 6.0mg of whole peanut for the Log-Normal, Log-Logistic, and Weibull models, respectively. The modeling of individual NOAELs and LOAELs identified from three different types of published studies - diagnostic series, threshold studies, and immunotherapy trials - yielded significantly different whole peanut ED(10)'s of 11.9 mg for threshold studies, 18.0mg for diagnostic series and 65.5mg for immunotherapy trials; patient selection and other biases may have influenced the estimates. These data and risk assessment models provide the type of information that is necessary to establish regulatory thresholds for peanut.

  1. Algorithms for recollection of search terms based on the Wikipedia category structure.

    PubMed

    Vandamme, Stijn; De Turck, Filip

    2014-01-01

    The common user interface for a search engine consists of a text field where the user can enter queries consisting of one or more keywords. Keyword query based search engines work well when the users have a clear vision what they are looking for and are capable of articulating their query using the same terms as indexed. For our multimedia database containing 202,868 items with text descriptions, we supplement such a search engine with a category-based interface whose category structure is tailored to the content of the database. This facilitates browsing and offers the users the possibility to look for named entities, even if they forgot their names. We demonstrate that this approach allows users who fail to recollect the name of named entities to retrieve data with little effort. In all our experiments, it takes 1 query on a category and on average 2.49 clicks, compared to 5.68 queries on the database's traditional text search engine for a 68.3% success probability or 6.01 queries when the user also turns to Google, for a 97.1% success probability.

  2. Hierarchical searching in model-based LADAR ATR using statistical separability tests

    NASA Astrophysics Data System (ADS)

    DelMarco, Stephen; Sobel, Erik; Douglas, Joel

    2006-05-01

    In this work we investigate simultaneous object identification improvement and efficient library search for model-based object recognition applications. We develop an algorithm to provide efficient, prioritized, hierarchical searching of the object model database. A common approach to model-based object recognition chooses the object label corresponding to the best match score. However, due to corrupting effects the best match score does not always correspond to the correct object model. To address this problem, we propose a search strategy which exploits information contained in a number of representative elements of the library to drill down to a small class with high probability of containing the object. We first optimally partition the library into a hierarchic taxonomy of disjoint classes. A small number of representative elements are used to characterize each object model class. At each hierarchy level, the observed object is matched against the representative elements of each class to generate score sets. A hypothesis testing problem, using a distribution-free statistical test, is defined on the score sets and used to choose the appropriate class for a prioritized search. We conduct a probabilistic analysis of the computational cost savings, and provide a formula measuring the computational advantage of the proposed approach. We generate numerical results using match scores derived from matching highly-detailed CAD models of civilian ground vehicles used in 3-D LADAR ATR. We present numerical results showing effects on classification performance of significance level and representative element number in the score set hypothesis testing problem.

  3. Is Internet search better than structured instruction for web-based health education?

    PubMed

    Finkelstein, Joseph; Bedra, McKenzie

    2013-01-01

    Internet provides access to vast amounts of comprehensive information regarding any health-related subject. Patients increasingly use this information for health education using a search engine to identify education materials. An alternative approach of health education via Internet is based on utilizing a verified web site which provides structured interactive education guided by adult learning theories. Comparison of these two approaches in older patients was not performed systematically. The aim of this study was to compare the efficacy of a web-based computer-assisted education (CO-ED) system versus searching the Internet for learning about hypertension. Sixty hypertensive older adults (age 45+) were randomized into control or intervention groups. The control patients spent 30 to 40 minutes searching the Internet using a search engine for information about hypertension. The intervention patients spent 30 to 40 minutes using the CO-ED system, which provided computer-assisted instruction about major hypertension topics. Analysis of pre- and post- knowledge scores indicated a significant improvement among CO-ED users (14.6%) as opposed to Internet users (2%). Additionally, patients using the CO-ED program rated their learning experience more positively than those using the Internet.

  4. Towards semantic search and inference in electronic medical records: An approach using concept--based information retrieval.

    PubMed

    Koopman, Bevan; Bruza, Peter; Sitbon, Laurianne; Lawley, Michael

    2012-01-01

    This paper presents a novel approach to searching electronic medical records that is based on concept matching rather than keyword matching. The concept-based approach is intended to overcome specific challenges we identified in searching medical records. Queries and documents were transformed from their term-based originals into medical concepts as defined by the SNOMED-CT ontology. Evaluation on a real-world collection of medical records showed our concept-based approach outperformed a keyword baseline by 25% in Mean Average Precision. The concept-based approach provides a framework for further development of inference based search systems for dealing with medical data.

  5. Pathfinder: multiresolution region-based searching of pathology images using IRM.

    PubMed

    Wang, J Z

    2000-01-01

    The fast growth of digitized pathology slides has created great challenges in research on image database retrieval. The prevalent retrieval technique involves human-supplied text annotations to describe slide contents. These pathology images typically have very high resolution, making it difficult to search based on image content. In this paper, we present Pathfinder, an efficient multiresolution region-based searching system for high-resolution pathology image libraries. The system uses wavelets and the IRM (Integrated Region Matching) distance. Experiments with a database of 70,000 pathology image fragments have demonstrated high retrieval accuracy and high speed. The algorithm can be combined with our previously developed wavelet-based progressive pathology image transmission and browsing algorithm and is expandable for medical image databases.

  6. Pathfinder: multiresolution region-based searching of pathology images using IRM.

    PubMed Central

    Wang, J. Z.

    2000-01-01

    The fast growth of digitized pathology slides has created great challenges in research on image database retrieval. The prevalent retrieval technique involves human-supplied text annotations to describe slide contents. These pathology images typically have very high resolution, making it difficult to search based on image content. In this paper, we present Pathfinder, an efficient multiresolution region-based searching system for high-resolution pathology image libraries. The system uses wavelets and the IRM (Integrated Region Matching) distance. Experiments with a database of 70,000 pathology image fragments have demonstrated high retrieval accuracy and high speed. The algorithm can be combined with our previously developed wavelet-based progressive pathology image transmission and browsing algorithm and is expandable for medical image databases. Images Figure 4 Figure 6 Figure 7 Figure 5 Figure 8 Figure 9 PMID:11080011

  7. Visualizing the search for radiation-damaged DNA bases in real time

    NASA Astrophysics Data System (ADS)

    Lee, Andrea J.; Wallace, Susan S.

    2016-11-01

    The Base Excision Repair (BER) pathway removes the vast majority of damages produced by ionizing radiation, including the plethora of radiation-damaged purines and pyrimidines. The first enzymes in the BER pathway are DNA glycosylases, which are responsible for finding and removing the damaged base. Although much is known about the biochemistry of DNA glycosylases, how these enzymes locate their specific damage substrates among an excess of undamaged bases has long remained a mystery. Here we describe the use of single molecule fluorescence to observe the bacterial DNA glycosylases, Nth, Fpg and Nei, scanning along undamaged and damaged DNA. We show that all three enzymes randomly diffuse on the DNA molecule and employ a wedge residue to search for and locate damage. The search behavior of the Escherichia coli DNA glycosylases likely provides a paradigm for their homologous mammalian counterparts.

  8. Lingos, finite state machines, and fast similarity searching.

    PubMed

    Grant, J Andrew; Haigh, James A; Pickup, Barry T; Nicholls, Anthony; Sayle, Roger A

    2006-01-01

    We apply a recently published method of text-based molecular similarity searching (LINGO) to standard data sets for the purpose of quantifying the accuracy of the approach. Our implementation is based on a pattern-matching finite state machine (FSM) which results in fast search times. The accuracy of LINGO is demonstrated to be comparable to that of a path-based fingerprint and offers a simple yet effective method for similarity searching.

  9. Search-matching algorithm for acoustics-based automatic sniper localization

    NASA Astrophysics Data System (ADS)

    Aguilar, Juan R.; Salinas, Renato A.; Abidi, Mongi A.

    2007-04-01

    Most of modern automatic sniper localization systems are based on the utilization of the acoustical emissions produced by the gun fire events. In order to estimate the spatial coordinates of the sniper location, these systems measures the time delay of arrival of the acoustical shock wave fronts to a microphone array. In more advanced systems, model based estimation of the nonlinear distortion parameters of the N-waves is used to make projectile trajectory and calibre estimations. In this work we address the sniper localization problem using a model based search-matching approach. The automatic sniper localization algorithm works searching for the acoustics model of ballistic shock waves which best matches the measured data. For this purpose, we implement a previously released acoustics model of ballistic shock waves. Further, the sniper location, the projectile trajectory and calibre, and the muzzle velocity are regarded as the inputs variables of such a model. A search algorithm is implemented in order to found what combination of the input variables minimize a fitness function defined as the distance between measured and simulated data. In such a way, the sniper location, the projectile trajectory and calibre, and the muzzle velocity can be found. In order to evaluate the performance of the algorithm, we conduct computer based experiments using simulated gunfire event data calculated at the nodes of a virtual distributed sensor network. Preliminary simulation results are quite promising showing fast convergence of the algorithm and good localization accuracy.

  10. On optimizing syntactic pattern recognition using tries and AI-based heuristic-search strategies.

    PubMed

    Badr, Ghada; Oommen, B John

    2006-06-01

    This paper deals with the problem of estimating, using enhanced artificial-intelligence (AI) techniques, a transmitted string X* by processing the corresponding string Y, which is a noisy version of X*. It is assumed that Y contains substitution, insertion, and deletion (SID) errors. The best estimate X+ of X* is defined as that element of a dictionary H that minimizes the generalized Levenshtein distance (GLD) D (X, Y) between X and Y, for all X epsilon H. In this paper, it is shown how to evaluate D (X, Y) for every X epsilon H simultaneously, when the edit distances are general and the maximum number of errors is not given a priori, and when H is stored as a trie. A new scheme called clustered beam search (CBS) is first introduced, which is a heuristic-based search approach that enhances the well-known beam-search (BS) techniques used in AI. The new scheme is then applied to the approximate string-matching problem when the dictionary is stored as a trie. The new technique is compared with the benchmark depth-first search (DFS) trie-based technique (with respect to time and accuracy) using large and small dictionaries. The results demonstrate a marked improvement of up to 75% with respect to the total number of operations needed on three benchmark dictionaries, while yielding an accuracy comparable to the optimal. Experiments are also done to show the benefits of the CBS over the BS when the search is done on the trie. The results also demonstrate a marked improvement (more than 91%) for large dictionaries.

  11. A Camera-Based Target Detection and Positioning UAV System for Search and Rescue (SAR) Purposes

    PubMed Central

    Sun, Jingxuan; Li, Boyang; Jiang, Yifan; Wen, Chih-yung

    2016-01-01

    Wilderness search and rescue entails performing a wide-range of work in complex environments and large regions. Given the concerns inherent in large regions due to limited rescue distribution, unmanned aerial vehicle (UAV)-based frameworks are a promising platform for providing aerial imaging. In recent years, technological advances in areas such as micro-technology, sensors and navigation have influenced the various applications of UAVs. In this study, an all-in-one camera-based target detection and positioning system is developed and integrated into a fully autonomous fixed-wing UAV. The system presented in this paper is capable of on-board, real-time target identification, post-target identification and location and aerial image collection for further mapping applications. Its performance is examined using several simulated search and rescue missions, and the test results demonstrate its reliability and efficiency. PMID:27792156

  12. Utilization of Tabu search heuristic rules in sampling-based motion planning

    NASA Astrophysics Data System (ADS)

    Khaksar, Weria; Hong, Tang Sai; Sahari, Khairul Salleh Mohamed; Khaksar, Mansoor

    2015-05-01

    Path planning in unknown environments is one of the most challenging research areas in robotics. In this class of path planning, the robot acquires the information from its sensory system. Sampling-based path planning is one of the famous approaches with low memory and computational requirements that has been studied by many researchers during the past few decades. We propose a sampling-based algorithm for path planning in unknown environments using Tabu search. The Tabu search component of the proposed method guides the sampling to find the samples in the most promising areas and makes the sampling procedure more intelligent. The simulation results show the efficient performance of the proposed approach in different types of environments. We also compare the performance of the algorithm with some of the well-known path planning approaches, including Bug1, Bug2, PRM, RRT and the Visibility Graph. The comparison results support the claim of superiority of the proposed algorithm.

  13. A Camera-Based Target Detection and Positioning UAV System for Search and Rescue (SAR) Purposes.

    PubMed

    Sun, Jingxuan; Li, Boyang; Jiang, Yifan; Wen, Chih-Yung

    2016-10-25

    Wilderness search and rescue entails performing a wide-range of work in complex environments and large regions. Given the concerns inherent in large regions due to limited rescue distribution, unmanned aerial vehicle (UAV)-based frameworks are a promising platform for providing aerial imaging. In recent years, technological advances in areas such as micro-technology, sensors and navigation have influenced the various applications of UAVs. In this study, an all-in-one camera-based target detection and positioning system is developed and integrated into a fully autonomous fixed-wing UAV. The system presented in this paper is capable of on-board, real-time target identification, post-target identification and location and aerial image collection for further mapping applications. Its performance is examined using several simulated search and rescue missions, and the test results demonstrate its reliability and efficiency.

  14. Local search methods based on variable focusing for random K -satisfiability

    NASA Astrophysics Data System (ADS)

    Lemoy, Rémi; Alava, Mikko; Aurell, Erik

    2015-01-01

    We introduce variable focused local search algorithms for satisfiabiliity problems. Usual approaches focus uniformly on unsatisfied clauses. The methods described here work by focusing on random variables in unsatisfied clauses. Variants are considered where variables are selected uniformly and randomly or by introducing a bias towards picking variables participating in several unsatistified clauses. These are studied in the case of the random 3-SAT problem, together with an alternative energy definition, the number of variables in unsatisfied constraints. The variable-based focused Metropolis search (V-FMS) is found to be quite close in performance to the standard clause-based FMS at optimal noise. At infinite noise, instead, the threshold for the linearity of solution times with instance size is improved by picking preferably variables in several UNSAT clauses. Consequences for algorithmic design are discussed.

  15. Generating "fragment-based virtual library" using pocket similarity search of ligand-receptor complexes.

    PubMed

    Khashan, Raed S

    2015-01-01

    As the number of available ligand-receptor complexes is increasing, researchers are becoming more dedicated to mine these complexes to aid in the drug design and development process. We present free software which is developed as a tool for performing similarity search across ligand-receptor complexes for identifying binding pockets which are similar to that of a target receptor. The search is based on 3D-geometric and chemical similarity of the atoms forming the binding pocket. For each match identified, the ligand's fragment(s) corresponding to that binding pocket are extracted, thus forming a virtual library of fragments (FragVLib) that is useful for structure-based drug design. The program provides a very useful tool to explore available databases.

  16. FPS-RAM: Fast Prefix Search RAM-Based Hardware for Forwarding Engine

    NASA Astrophysics Data System (ADS)

    Zaitsu, Kazuya; Yamamoto, Koji; Kuroda, Yasuto; Inoue, Kazunari; Ata, Shingo; Oka, Ikuo

    Ternary content addressable memory (TCAM) is becoming very popular for designing high-throughput forwarding engines on routers. However, TCAM has potential problems in terms of hardware and power costs, which limits its ability to deploy large amounts of capacity in IP routers. In this paper, we propose new hardware architecture for fast forwarding engines, called fast prefix search RAM-based hardware (FPS-RAM). We designed FPS-RAM hardware with the intent of maintaining the same search performance and physical user interface as TCAM because our objective is to replace the TCAM in the market. Our RAM-based hardware architecture is completely different from that of TCAM and has dramatically reduced the costs and power consumption to 62% and 52%, respectively. We implemented FPS-RAM on an FPGA to examine its lookup operation.

  17. An Experimentally Based Computer Search Identifies Unstructured Membrane-binding Sites in Proteins

    PubMed Central

    Brzeska, Hanna; Guag, Jake; Remmert, Kirsten; Chacko, Susan; Korn, Edward D.

    2010-01-01

    Programs exist for searching protein sequences for potential membrane-penetrating segments (hydrophobic regions) and for lipid-binding sites with highly defined tertiary structures, such as PH, FERM, C2, ENTH, and other domains. However, a rapidly growing number of membrane-associated proteins (including cytoskeletal proteins, kinases, GTP-binding proteins, and their effectors) bind lipids through less structured regions. Here, we describe the development and testing of a simple computer search program that identifies unstructured potential membrane-binding sites. Initially, we found that both basic and hydrophobic amino acids, irrespective of sequence, contribute to the binding to acidic phospholipid vesicles of synthetic peptides that correspond to the putative membrane-binding domains of Acanthamoeba class I myosins. Based on these results, we modified a hydrophobicity scale giving Arg- and Lys-positive, rather than negative, values. Using this basic and hydrophobic scale with a standard search algorithm, we successfully identified previously determined unstructured membrane-binding sites in all 16 proteins tested. Importantly, basic and hydrophobic searches identified previously unknown potential membrane-binding sites in class I myosins, PAKs and CARMIL (capping protein, Arp2/3, myosin I linker; a membrane-associated cytoskeletal scaffold protein), and synthetic peptides and protein domains containing these newly identified sites bound to acidic phospholipids in vitro. PMID:20018884

  18. A minimal path searching approach for active shape model (ASM)-based segmentation of the lung

    NASA Astrophysics Data System (ADS)

    Guo, Shengwen; Fei, Baowei

    2009-02-01

    We are developing a minimal path searching method for active shape model (ASM)-based segmentation for detection of lung boundaries on digital radiographs. With the conventional ASM method, the position and shape parameters of the model points are iteratively refined and the target points are updated by the least Mahalanobis distance criterion. We propose an improved searching strategy that extends the searching points in a fan-shape region instead of along the normal direction. A minimal path (MP) deformable model is applied to drive the searching procedure. A statistical shape prior model is incorporated into the segmentation. In order to keep the smoothness of the shape, a smooth constraint is employed to the deformable model. To quantitatively assess the ASM-MP segmentation, we compare the automatic segmentation with manual segmentation for 72 lung digitized radiographs. The distance error between the ASM-MP and manual segmentation is 1.75 +/- 0.33 pixels, while the error is 1.99 +/- 0.45 pixels for the ASM. Our results demonstrate that our ASM-MP method can accurately segment the lung on digital radiographs.

  19. Effective leveraging of targeted search spaces for improving peptide identification in MS/MS based proteomics

    PubMed Central

    Shanmugam, Avinash K.; Nesvizhski, Alexey I.

    2016-01-01

    In shotgun proteomics, peptides are typically identified using database searching which involves scoring acquired tandem mass spectra against peptides derived from standard protein sequence databases such as Uniprot, Refseq, or Ensembl. In this strategy, the sensitivity of peptide identification is known to be affected by the size of the search space. Therefore, creating a targeted sequence database containing only peptides likely to be present in the analyzed sample can be a useful technique for improving the sensitivity of peptide identification. In this study we describe how targeted peptide databases can be created based on the frequency of identification in GPMDB – the largest publicly available repository of peptide and protein identification data. We demonstrate that targeted peptide databases can be easily integrated into existing proteome analysis workflows, and describe a computational strategy for minimizing any loss of peptide identifications arising from potential search space incompleteness in the targeted search spaces. We demonstrate the performance of our workflow using several datasets of varying size and sample complexity. PMID:26569054

  20. Assessment of color search performance in photopic and mesopic illuminances based on color identification data

    NASA Astrophysics Data System (ADS)

    Ishida, Taiichiro

    2002-06-01

    Color is an effective attribute as an aid to a visual task. Appearance of colors, however, remarkably changes with viewing conditions. In particular, lighting environment has strong effects on the appearance of surface colors. To use colors effectively, we must know how colors are identified under various lighting conditions. In our previous studies, we obtained the data on identification of colors under illuminances from photopic to mesopic levels. In this study we examined performance of a color related searching task under photopic and mesopic illuminance levels, and evaluated it based on the color identification data. Subjects searched the target three-digits printed on a card from among 45 cards. At the same time, a color chip was pasted on each plate as a clue. Before each trial the subjects were informed of the number and color name for the target on that trial. If the subjects could identify colors properly,.the searching performance must be improved. As might be expected, the performance of the task declined with decreasing illuminances and size of the color chip. It was found that the searching performance correlated with probability of being identified as the target color.

  1. Security and Privacy in a Sensor-Based Search and Rescue System

    NASA Astrophysics Data System (ADS)

    Huang, Jyh-How; Black, John; Mishra, Shivakant

    With the emergence of small devices equipped with wireless communication, several sophisticated systems for search and rescue have been proposed and developed. However, a key obstacle in large deployment of these systems is vulnerability to users' security and privacy. On one hand, search and rescue systems need to collect as much information about a user's location and movement as possible to locate that user in a timely manner. On the other hand, this very capability can be misused by adversaries to stalk a person, which in turn drives users away from using such a system. This paper describes the design, implementation and performance of a security and privacy framework for SenSearch, which is a sensor-based search and rescue system for people in emergency situation in wilderness areas. This framework has been carefully built by employing a combination of symmetric and asymmetric key cryptography to meet the constraints of resource-limited devices and short time intervals during which most security operations have to be performed.

  2. Distributed Search and Pattern Matching

    NASA Astrophysics Data System (ADS)

    Ahmed, Reaz; Boutaba, Raouf

    Peer-to-peer (P2P) technology has triggered a wide range of distributed applications including file-sharing, distributed XML databases, distributed computing, server-less web publishing and networked resource/service sharing. Despite of the diversity in application, these systems share common requirements for searching due to transitory nodes population and content volatility. In such dynamic environment, users do not have the exact information about available resources. Queries are based on partial information. This mandates the search mechanism to be emphflexible. On the other hand, the search mechanism is required to be bandwidth emphefficient to support large networks. Variety of search techniques have been proposed to provide satisfactory solution to the conflicting requirements of search efficiency and flexibility. This chapter highlights the search requirements in large scale distributed systems and the ability of the existing distributed search techniques in satisfying these requirements. Representative search techniques from three application domains, namely, P2P content sharing, service discovery and distributed XML databases, are considered. An abstract problem formulation called Distributed Pattern Matching (DPM) is presented as well. The DPM framework can be used as a common ground for addressing the search problem in these three application domains.

  3. How Users Search the Library from a Single Search Box

    ERIC Educational Resources Information Center

    Lown, Cory; Sierra, Tito; Boyer, Josh

    2013-01-01

    Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…

  4. How Users Search the Library from a Single Search Box

    ERIC Educational Resources Information Center

    Lown, Cory; Sierra, Tito; Boyer, Josh

    2013-01-01

    Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…

  5. A neotropical Miocene pollen database employing image-based search and semantic modeling1

    PubMed Central

    Han, Jing Ginger; Cao, Hongfei; Barb, Adrian; Punyasena, Surangi W.; Jaramillo, Carlos; Shyu, Chi-Ren

    2014-01-01

    • Premise of the study: Digital microscopic pollen images are being generated with increasing speed and volume, producing opportunities to develop new computational methods that increase the consistency and efficiency of pollen analysis and provide the palynological community a computational framework for information sharing and knowledge transfer. • Methods: Mathematical methods were used to assign trait semantics (abstract morphological representations) of the images of neotropical Miocene pollen and spores. Advanced database-indexing structures were built to compare and retrieve similar images based on their visual content. A Web-based system was developed to provide novel tools for automatic trait semantic annotation and image retrieval by trait semantics and visual content. • Results: Mathematical models that map visual features to trait semantics can be used to annotate images with morphology semantics and to search image databases with improved reliability and productivity. Images can also be searched by visual content, providing users with customized emphases on traits such as color, shape, and texture. • Discussion: Content- and semantic-based image searches provide a powerful computational platform for pollen and spore identification. The infrastructure outlined provides a framework for building a community-wide palynological resource, streamlining the process of manual identification, analysis, and species discovery. PMID:25202648

  6. A Publisher view on the future of scholarly publishing

    NASA Astrophysics Data System (ADS)

    Stoop, Jose

    2015-08-01

    The journal publishing landscape is changing rapidly. With the massive move from print to online taking place at the end of the last century, we are now seeing a shift from traditional subscription based publishing model to ‘hybrid’ models and full Open Access publishing. Other major changes are taking place at the article interface level (from a static PDF to the “Article of the Future”), in data and code repository linking, in publishing data and code and hence make it citable and discoverable, and in many other subject area specific online innovations that are being introduced.Elsevier is actively involved - both in Open Access publishing, and in content innovation - in discussing, and taking the lead through many big and smaller scale initiatives. This presentation will outline Elsevier’s perspective on the future of scientific publishing with regards to these developments.

  7. Anatomy and evolution of database search engines-a central component of mass spectrometry based proteomic workflows.

    PubMed

    Verheggen, Kenneth; Raeder, Helge; Berven, Frode S; Martens, Lennart; Barsnes, Harald; Vaudel, Marc

    2017-09-13

    Sequence database search engines are bioinformatics algorithms that identify peptides from tandem mass spectra using a reference protein sequence database. Two decades of development, notably driven by advances in mass spectrometry, have provided scientists with more than 30 published search engines, each with its own properties. In this review, we present the common paradigm behind the different implementations, and its limitations for modern mass spectrometry datasets. We also detail how the search engines attempt to alleviate these limitations, and provide an overview of the different software frameworks available to the researcher. Finally, we highlight alternative approaches for the identification of proteomic mass spectrometry datasets, either as a replacement for, or as a complement to, sequence database search engines. © 2017 Wiley Periodicals, Inc.

  8. Sharing our data—An overview of current (2016) USGS policies and practices for publishing data on ScienceBase and an example interactive mapping application

    USGS Publications Warehouse

    Chase, Katherine J.; Bock, Andrew R.; Sando, Roy

    2017-01-05

    This report provides an overview of current (2016) U.S. Geological Survey policies and practices related to publishing data on ScienceBase, and an example interactive mapping application to display those data. ScienceBase is an integrated data sharing platform managed by the U.S. Geological Survey. This report describes resources that U.S. Geological Survey Scientists can use for writing data management plans, formatting data, and creating metadata, as well as for data and metadata review, uploading data and metadata to ScienceBase, and sharing metadata through the U.S. Geological Survey Science Data Catalog. Because data publishing policies and practices are evolving, scientists should consult the resources cited in this paper for definitive policy information.An example is provided where, using the content of a published ScienceBase data release that is associated with an interpretive product, a simple user interface is constructed to demonstrate how the open source capabilities of the R programming language and environment can interact with the properties and objects of the ScienceBase item and be used to generate interactive maps.

  9. Embracing Electronic Publishing.

    ERIC Educational Resources Information Center

    Wills, Gordon

    1996-01-01

    Electronic publishing is the grandest revolution in the capture and dissemination of academic and professional knowledge since Caxton developed the printing press. This article examines electronic publishing, describes different electronic publishing scenarios (authors' cooperative, consolidator/retailer/agent oligopsony, publisher oligopoly), and…

  10. Embracing Electronic Publishing.

    ERIC Educational Resources Information Center

    Wills, Gordon

    1996-01-01

    Electronic publishing is the grandest revolution in the capture and dissemination of academic and professional knowledge since Caxton developed the printing press. This article examines electronic publishing, describes different electronic publishing scenarios (authors' cooperative, consolidator/retailer/agent oligopsony, publisher oligopoly), and…

  11. Fast online and index-based algorithms for approximate search of RNA sequence-structure patterns

    PubMed Central

    2013-01-01

    Background It is well known that the search for homologous RNAs is more effective if both sequence and structure information is incorporated into the search. However, current tools for searching with RNA sequence-structure patterns cannot fully handle mutations occurring on both these levels or are simply not fast enough for searching large sequence databases because of the high computational costs of the underlying sequence-structure alignment problem. Results We present new fast index-based and online algorithms for approximate matching of RNA sequence-structure patterns supporting a full set of edit operations on single bases and base pairs. Our methods efficiently compute semi-global alignments of structural RNA patterns and substrings of the target sequence whose costs satisfy a user-defined sequence-structure edit distance threshold. For this purpose, we introduce a new computing scheme to optimally reuse the entries of the required dynamic programming matrices for all substrings and combine it with a technique for avoiding the alignment computation of non-matching substrings. Our new index-based methods exploit suffix arrays preprocessed from the target database and achieve running times that are sublinear in the size of the searched sequences. To support the description of RNA molecules that fold into complex secondary structures with multiple ordered sequence-structure patterns, we use fast algorithms for the local or global chaining of approximate sequence-structure pattern matches. The chaining step removes spurious matches from the set of intermediate results, in particular of patterns with little specificity. In benchmark experiments on the Rfam database, our improved online algorithm is faster than the best previous method by up to factor 45. Our best new index-based algorithm achieves a speedup of factor 560. Conclusions The presented methods achieve considerable speedups compared to the best previous method. This, together with the expected

  12. Fast online and index-based algorithms for approximate search of RNA sequence-structure patterns.

    PubMed

    Meyer, Fernando; Kurtz, Stefan; Beckstette, Michael

    2013-07-17

    It is well known that the search for homologous RNAs is more effective if both sequence and structure information is incorporated into the search. However, current tools for searching with RNA sequence-structure patterns cannot fully handle mutations occurring on both these levels or are simply not fast enough for searching large sequence databases because of the high computational costs of the underlying sequence-structure alignment problem. We present new fast index-based and online algorithms for approximate matching of RNA sequence-structure patterns supporting a full set of edit operations on single bases and base pairs. Our methods efficiently compute semi-global alignments of structural RNA patterns and substrings of the target sequence whose costs satisfy a user-defined sequence-structure edit distance threshold. For this purpose, we introduce a new computing scheme to optimally reuse the entries of the required dynamic programming matrices for all substrings and combine it with a technique for avoiding the alignment computation of non-matching substrings. Our new index-based methods exploit suffix arrays preprocessed from the target database and achieve running times that are sublinear in the size of the searched sequences. To support the description of RNA molecules that fold into complex secondary structures with multiple ordered sequence-structure patterns, we use fast algorithms for the local or global chaining of approximate sequence-structure pattern matches. The chaining step removes spurious matches from the set of intermediate results, in particular of patterns with little specificity. In benchmark experiments on the Rfam database, our improved online algorithm is faster than the best previous method by up to factor 45. Our best new index-based algorithm achieves a speedup of factor 560. The presented methods achieve considerable speedups compared to the best previous method. This, together with the expected sublinear running time of the presented

  13. Chemical compound navigator: a web-based chem-BLAST, chemical taxonomy-based search engine for browsing compounds.

    PubMed

    Prasanna, M D; Vondrasek, Jiri; Wlodawer, Alexander; Rodriguez, H; Bhat, T N

    2006-06-01

    A novel technique to annotate, query, and analyze chemical compounds has been developed and is illustrated by using the inhibitor data on HIV protease-inhibitor complexes. In this method, all chemical compounds are annotated in terms of standard chemical structural fragments. These standard fragments are defined by using criteria, such as chemical classification; structural, chemical, or functional groups; and commercial, scientific or common names or synonyms. These fragments are then organized into a data tree based on their chemical substructures. Search engines have been developed to use this data tree to enable query on inhibitors of HIV protease (http://xpdb.nist.gov/hivsdb/hivsdb.html). These search engines use a new novel technique, Chemical Block Layered Alignment of Substructure Technique (Chem-BLAST) to search on the fragments of an inhibitor to look for its chemical structural neighbors. This novel technique to annotate and query compounds lays the foundation for the use of the Semantic Web concept on chemical compounds to allow end users to group, sort, and search structural neighbors accurately and efficiently. During annotation, it enables the attachment of "meaning" (i.e., semantics) to data in a manner that far exceeds the current practice of associating "metadata" with data by creating a knowledge base (or ontology) associated with compounds. Intended users of the technique are the research community and pharmaceutical industry, for which it will provide a new tool to better identify novel chemical structural neighbors to aid drug discovery.

  14. Genome-scale NCRNA homology search using a Hamming distance-based filtration strategy

    PubMed Central

    2012-01-01

    Background NCRNAs (noncoding RNAs) play important roles in many biological processes. Existing genome-scale ncRNA search tools identify ncRNAs in local sequence alignments generated by conventional sequence comparison methods. However, some types of ncRNA lack strong sequence conservation and tend to be missed or mis-aligned by conventional sequence comparison. Results In this paper, we propose an ncRNA identification framework that is complementary to existing sequence comparison tools. By integrating a filtration step based on Hamming distance and ncRNA alignment programs such as FOLDALIGN or PLAST-ncRNA, the proposed ncRNA search framework can identify ncRNAs that lack strong sequence conservation. In addition, as the ratio of transition and transversion mutation is often used as a discriminative feature for functional ncRNA identification, we incorporate this feature into the filtration step using a coding strategy. We apply Hamming distance seeds to ncRNA search in the intergenic regions of human and mouse genomes and between the Burkholderia cenocepacia J2315 genome and the Ralstonia solanacearum genome. The experimental results demonstrate that a carefully designed Hamming distance seed can achieve better sensitivity in searching for poorly conserved ncRNAs than conventional sequence comparison tools. Conclusions Hamming distance seeds provide better sensitivity as a filtration strategy for genome-wide ncRNA homology search than the existing seeding strategies used in BLAST-like tools. By combining Hamming distance seeds matching and ncRNA alignment, we are able to find ncRNAs with sequence similarities below 60%. PMID:22536896

  15. Development and evaluation of a biomedical search engine using a predicate-based vector space model.

    PubMed

    Kwak, Myungjae; Leroy, Gondy; Martinez, Jesse D; Harwell, Jeffrey

    2013-10-01

    Although biomedical information available in articles and patents is increasing exponentially, we continue to rely on the same information retrieval methods and use very few keywords to search millions of documents. We are developing a fundamentally different approach for finding much more precise and complete information with a single query using predicates instead of keywords for both query and document representation. Predicates are triples that are more complex datastructures than keywords and contain more structured information. To make optimal use of them, we developed a new predicate-based vector space model and query-document similarity function with adjusted tf-idf and boost function. Using a test bed of 107,367 PubMed abstracts, we evaluated the first essential function: retrieving information. Cancer researchers provided 20 realistic queries, for which the top 15 abstracts were retrieved using a predicate-based (new) and keyword-based (baseline) approach. Each abstract was evaluated, double-blind, by cancer researchers on a 0-5 point scale to calculate precision (0 versus higher) and relevance (0-5 score). Precision was significantly higher (p<.001) for the predicate-based (80%) than for the keyword-based (71%) approach. Relevance was almost doubled with the predicate-based approach-2.1 versus 1.6 without rank order adjustment (p<.001) and 1.34 versus 0.98 with rank order adjustment (p<.001) for predicate--versus keyword-based approach respectively. Predicates can support more precise searching than keywords, laying the foundation for rich and sophisticated information search. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. The Decision to Publish Electronically.

    ERIC Educational Resources Information Center

    Craig, Gary

    1983-01-01

    Argues that decision to publish a given intellectual product "electronically" is a business decision based on customer needs, available format alternatives, current business climate, and variety of already existing factors. Publishers are most influenced by customers' acceptance of new products and their own role as intermediaries in…

  17. The Decision to Publish Electronically.

    ERIC Educational Resources Information Center

    Craig, Gary

    1983-01-01

    Argues that decision to publish a given intellectual product "electronically" is a business decision based on customer needs, available format alternatives, current business climate, and variety of already existing factors. Publishers are most influenced by customers' acceptance of new products and their own role as intermediaries in…

  18. Publishing Information on Individual Schools?

    ERIC Educational Resources Information Center

    van Petegem, P.; Vanhoof, J.; Daems, F.; Mahieu, P.

    2005-01-01

    Publishing data on individual schools is becoming a common practice in more and more countries. Based on an extensive study of literature and interviews with experts in England, Scotland, The Netherlands, and France, this article reveals that publishing individual school data is not only a contested but also a very complex affair. Different…

  19. Internet-based search of randomised trials relevant to mental health originating in the Arab world

    PubMed Central

    Takriti, Yahya; El-Sayeh, Hany G; Adams, Clive E

    2005-01-01

    Background The internet is becoming a widely used source of accessing medical research through various on-line databases. This instant access to information is of benefit to busy clinicians and service users around the world. The population of the Arab World is comparable to that of the United States, yet it is widely believed to have a greatly contrasting output of randomised controlled trials related to mental health. This study was designed to investigate the existence of such research in the Arab World and also to investigate the availability of this research on-line. Methods Survey of findings from three internet-based potential sources of randomised trials originating from the Arab world and relevant to mental health care. Results A manual search of an Arabic online current contents service identified 3 studies, MEDLINE, EMBASE, and PsycINFO searches identified only 1 study, and a manual search of a specifically indexed, study-based mental health database, PsiTri, revealed 27 trials. Conclusion There genuinely seem to be few trials from the Arab world and accessing these on-line was problematic. Replication of some studies that guide psychiatric/psychological practice in the Arab world would seem prudent. PMID:16045805

  20. A model independent S/W framework for search-based software testing.

    PubMed

    Oh, Jungsup; Baik, Jongmoon; Lim, Sung-Hwa

    2014-01-01

    In Model-Based Testing (MBT) area, Search-Based Software Testing (SBST) has been employed to generate test cases from the model of a system under test. However, many types of models have been used in MBT. If the type of a model has changed from one to another, all functions of a search technique must be reimplemented because the types of models are different even if the same search technique has been applied. It requires too much time and effort to implement the same algorithm over and over again. We propose a model-independent software framework for SBST, which can reduce redundant works. The framework provides a reusable common software platform to reduce time and effort. The software framework not only presents design patterns to find test cases for a target model but also reduces development time by using common functions provided in the framework. We show the effectiveness and efficiency of the proposed framework with two case studies. The framework improves the productivity by about 50% when changing the type of a model.

  1. Optimum wavelet based masking for the contrast enhancement of medical images using enhanced cuckoo search algorithm.

    PubMed

    Daniel, Ebenezer; Anitha, J

    2016-04-01

    Unsharp masking techniques are a prominent approach in contrast enhancement. Generalized masking formulation has static scale value selection, which limits the gain of contrast. In this paper, we propose an Optimum Wavelet Based Masking (OWBM) using Enhanced Cuckoo Search Algorithm (ECSA) for the contrast improvement of medical images. The ECSA can automatically adjust the ratio of nest rebuilding, using genetic operators such as adaptive crossover and mutation. First, the proposed contrast enhancement approach is validated quantitatively using Brain Web and MIAS database images. Later, the conventional nest rebuilding of cuckoo search optimization is modified using Adaptive Rebuilding of Worst Nests (ARWN). Experimental results are analyzed using various performance matrices, and our OWBM shows improved results as compared with other reported literature.

  2. A quantum-behaved evolutionary algorithm based on the Bloch spherical search

    NASA Astrophysics Data System (ADS)

    Li, Panchi

    2014-04-01

    In order to enhance the optimization ability of the quantum evolutionary algorithms, a new quantum-behaved evolutionary algorithm is proposed. In this algorithm, the search mechanism is established based on the Bloch sphere. First, the individuals are expressed by qubits described on the Bloch sphere, then the rotation axis is established by Pauli matrixes, and the evolution search is realized by rotating qubits on the Bloch sphere about the rotating axis. In order to avoid premature convergence, the mutation of individuals is achieved by the Hadamard gates. Such rotation can make the current qubit approximate the target qubit along with the great circle on the Bloch sphere, which can accelerate optimization process. Taking the function extreme value optimization as an example, the experimental results show that the proposed algorithm is obviously superior to other similar algorithms.

  3. The Challenge of Commercial Document Retrieval, Part II: A Strategy for Document Searching Based on Identifiable Document Partitions.

    ERIC Educational Resources Information Center

    Blair, David C.

    2002-01-01

    Discussion of commercial document retrieval focuses on a two-part searching procedure based on identifiable partitions. Topics include system growth and the effects of information technology; content searching on large databases, including partitioning; the granularity of context; resolving queries; document retrieval and the World Wide Web; and…

  4. Web-Based Undergraduate Chemistry Problem-Solving: The Interplay of Task Performance, Domain Knowledge and Web-Searching Strategies

    ERIC Educational Resources Information Center

    She, Hsiao-Ching; Cheng, Meng-Tzu; Li, Ta-Wei; Wang, Chia-Yu; Chiu, Hsin-Tien; Lee, Pei-Zon; Chou, Wen-Chi; Chuang, Ming-Hua

    2012-01-01

    This study investigates the effect of Web-based Chemistry Problem-Solving, with the attributes of Web-searching and problem-solving scaffolds, on undergraduate students' problem-solving task performance. In addition, the nature and extent of Web-searching strategies students used and its correlation with task performance and domain knowledge also…

  5. Reviewing Ligand-Based Rational Drug Design: The Search for an ATP Synthase Inhibitor

    PubMed Central

    Lee, Chia-Hsien; Huang, Hsuan-Cheng; Juan, Hsueh-Fen

    2011-01-01

    Following major advances in the field of medicinal chemistry, novel drugs can now be designed systematically, instead of relying on old trial and error approaches. Current drug design strategies can be classified as being either ligand- or structure-based depending on the design process. In this paper, by describing the search for an ATP synthase inhibitor, we review two frequently used approaches in ligand-based drug design: The pharmacophore model and the quantitative structure-activity relationship (QSAR) method. Moreover, since ATP synthase ligands are potentially useful drugs in cancer therapy, pharmacophore models were constructed to pave the way for novel inhibitor designs. PMID:21954360

  6. SearchLight: a freely available web-based quantitative spectral analysis tool (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Prabhat, Prashant; Peet, Michael; Erdogan, Turan

    2016-03-01

    In order to design a fluorescence experiment, typically the spectra of a fluorophore and of a filter set are overlaid on a single graph and the spectral overlap is evaluated intuitively. However, in a typical fluorescence imaging system the fluorophores and optical filters are not the only wavelength dependent variables - even the excitation light sources have been changing. For example, LED Light Engines may have a significantly different spectral response compared to the traditional metal-halide lamps. Therefore, for a more accurate assessment of fluorophore-to-filter-set compatibility, all sources of spectral variation should be taken into account simultaneously. Additionally, intuitive or qualitative evaluation of many spectra does not necessarily provide a realistic assessment of the system performance. "SearchLight" is a freely available web-based spectral plotting and analysis tool that can be used to address the need for accurate, quantitative spectral evaluation of fluorescence measurement systems. This tool is available at: http://searchlight.semrock.com/. Based on a detailed mathematical framework [1], SearchLight calculates signal, noise, and signal-to-noise ratio for multiple combinations of fluorophores, filter sets, light sources and detectors. SearchLight allows for qualitative and quantitative evaluation of the compatibility of filter sets with fluorophores, analysis of bleed-through, identification of optimized spectral edge locations for a set of filters under specific experimental conditions, and guidance regarding labeling protocols in multiplexing imaging assays. Entire SearchLight sessions can be shared with colleagues and collaborators and saved for future reference. [1] Anderson, N., Prabhat, P. and Erdogan, T., Spectral Modeling in Fluorescence Microscopy, http://www.semrock.com (2010).

  7. Etiquette in scientific publishing.

    PubMed

    Krishnan, Vinod

    2013-10-01

    Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be followed in scientific publishing. In an environment where "publish or perish" rules the day, some authors might be tempted to bend or break rules. This special article is intended to raise awareness among orthodontic journal editors, authors, and readers about the types of scientific misconduct in the current publishing scenario and to provide insight into the ways these misconducts are managed by the Committee of Publishing Ethics. Case studies are presented, and various plagiarism detection software programs used by publishing companies are briefly described. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  8. Alternative Publishing and Education

    ERIC Educational Resources Information Center

    Perron, Jack

    1973-01-01

    A guide to the underground education publishers and their products. The guide discusses the reasons underground publishers exist and suggests ways in which they have influenced the giants. (Author/DN)

  9. Darwin and his publisher.

    PubMed

    McClay, David

    2009-01-01

    Charles Darwin's publisher John Murray played an important, if often underrated, role in bringing his theories to the public. As their letters and publishing archives show they had a friendly, business like and successful relationship. This was despite fundamental scientific and religious differences between the men. In addition to publishing Darwin, Murray also published many of the critical and supportive works and reviews which Darwin's own works excited.

  10. The Surface Extraction from TIN based Search-space Minimization (SETSM) algorithm

    NASA Astrophysics Data System (ADS)

    Noh, Myoung-Jong; Howat, Ian M.

    2017-07-01

    Digital Elevation Models (DEMs) provide critical information for a wide range of scientific, navigational and engineering activities. Submeter resolution, stereoscopic satellite imagery with high geometric and radiometric quality, and wide spatial coverage are becoming increasingly accessible for generating stereo-photogrammetric DEMs. However, low contrast and repeatedly-textured surfaces, such as snow and glacial ice at high latitudes, and mountainous terrains challenge existing stereo-photogrammetric DEM generation techniques, particularly without a-priori information such as existing seed DEMs or the manual setting of terrain-specific parameters. To utilize these data for fully-automatic DEM extraction at a large scale, we developed the Surface Extraction from TIN-based Search-space Minimization (SETSM) algorithm. SETSM is fully automatic (i.e. no search parameter settings are needed) and uses only the sensor model Rational Polynomial Coefficients (RPCs). SETSM adopts a hierarchical, combined image- and object-space matching strategy utilizing weighted normalized cross-correlation with both original distorted and geometrically corrected images for overcoming ambiguities caused by foreshortening and occlusions. In addition, SETSM optimally minimizes search-spaces to extract optimal matches over problematic terrains by iteratively updating object surfaces within a Triangulated Irregular Network, and utilizes a geometric-constrained blunder and outlier detection in object space. We prove the ability of SETSM to mitigate typical stereo-photogrammetric matching problems over a range of challenging terrains. SETSM is the primary DEM generation software for the US National Science Foundation's ArcticDEM project.

  11. Feasibility of using molecular docking-based virtual screening for searching dual target kinase inhibitors.

    PubMed

    Zhou, Shunye; Li, Youyong; Hou, Tingjun

    2013-04-22

    Multitarget agents have been extensively explored for solving limited efficacies, poor safety, and resistant profiles of an individual target. Theoretical approaches for searching and designing multitarget agents are critically useful. Here, the performance of molecular docking to search dual-target inhibitors for four kinase pairs (CDK2-GSK3B, EGFR-Src, Lck-Src, and Lck-VEGFR2) was assessed. First, the representative structures for each kinase target were chosen by structural clustering of available crystal structures. Next, the performance of molecular docking to distinguish inhibitors from noninhibitors for each individual kinase target was evaluated. The results show that molecular docking-based virtual screening illustrates good capability to find known inhibitors for individual targets, but the prediction accuracy is structurally dependent. Finally, the performance of molecular docking to identify the dual-target kinase inhibitors for four kinase pairs was evaluated. The analyses show that molecular docking successfully filters out most noninhibitors and achieves promising performance for identifying dual-kinase inhibitors for CDK2-GSK3B and Lck-VEGFR2. But a high false-positive rate leads to low enrichment of true dual-target inhibitors in the final list. This study suggests that molecular docking serves as a useful tool in searching inhibitors against dual or even multiple kinase targets, but integration with other virtual screening tools is necessary for achieving better predictions.

  12. Model-based Layer Estimation using a Hybrid Genetic/Gradient Search Optimization Algorithm

    SciTech Connect

    Chambers, D; Lehman, S; Dowla, F

    2007-05-17

    A particle swarm optimization (PSO) algorithm is combined with a gradient search method in a model-based approach for extracting interface positions in a one-dimensional multilayer structure from acoustic or radar reflections. The basic approach is to predict the reflection measurement using a simulation of one-dimensional wave propagation in a multi-layer, evaluate the error between prediction and measurement, and then update the simulation parameters to minimize the error. Gradient search methods alone fail due to the number of local minima in the error surface close to the desired global minimum. The PSO approach avoids this problem by randomly sampling the region of the error surface around the global minimum, but at the cost of a large number of evaluations of the simulator. The hybrid approach uses the PSO at the beginning to locate the general area around the global minimum then switches to the gradient search method to zero in on it. Examples of the algorithm applied to the detection of interior walls of a building from reflected ultra-wideband radar signals are shown. Other possible applications are optical inspection of coatings and ultrasonic measurement of multilayer structures.

  13. New Internet search volume-based weighting method for integrating various environmental impacts

    SciTech Connect

    Ji, Changyoon Hong, Taehoon

    2016-01-15

    Weighting is one of the steps in life cycle impact assessment that integrates various characterized environmental impacts as a single index. Weighting factors should be based on the society's preferences. However, most previous studies consider only the opinion of some people. Thus, this research proposes a new weighting method that determines the weighting factors of environmental impact categories by considering public opinion on environmental impacts using the Internet search volumes for relevant terms. To validate the new weighting method, the weighting factors for six environmental impacts calculated by the new weighting method were compared with the existing weighting factors. The resulting Pearson's correlation coefficient between the new and existing weighting factors was from 0.8743 to 0.9889. It turned out that the new weighting method presents reasonable weighting factors. It also requires less time and lower cost compared to existing methods and likewise meets the main requirements of weighting methods such as simplicity, transparency, and reproducibility. The new weighting method is expected to be a good alternative for determining the weighting factor. - Highlight: • A new weighting method using Internet search volume is proposed in this research. • The new weighting method reflects the public opinion using Internet search volume. • The correlation coefficient between new and existing weighting factors is over 0.87. • The new weighting method can present the reasonable weighting factors. • The proposed method can be a good alternative for determining the weighting factors.

  14. Pulsar Timing Array Based Search for Supermassive Black Hole Binaries in the Square Kilometer Array Era.

    PubMed

    Wang, Yan; Mohanty, Soumya D

    2017-04-14

    The advent of next generation radio telescope facilities, such as the Square Kilometer Array (SKA), will usher in an era where a pulsar timing array (PTA) based search for gravitational waves (GWs) will be able to use hundreds of well timed millisecond pulsars rather than the few dozens in existing PTAs. A realistic assessment of the performance of such an extremely large PTA must take into account the data analysis challenge posed by an exponential increase in the parameter space volume due to the large number of so-called pulsar phase parameters. We address this problem and present such an assessment for isolated supermassive black hole binary (SMBHB) searches using a SKA era PTA containing 10^{3} pulsars. We find that an all-sky search will be able to confidently detect nonevolving sources with a redshifted chirp mass of 10^{10}  M_{⊙} out to a redshift of about 28 (corresponding to a rest-frame chirp mass of 3.4×10^{8}  M_{⊙}). We discuss the important implications that the large distance reach of a SKA era PTA has on GW observations from optically identified SMBHB candidates. If no SMBHB detections occur, a highly unlikely scenario in the light of our results, the sky-averaged upper limit on strain amplitude will be improved by about 3 orders of magnitude over existing limits.

  15. PseudoBase++: an extension of PseudoBase for easy searching, formatting and visualization of pseudoknots.

    PubMed

    Taufer, Michela; Licon, Abel; Araiza, Roberto; Mireles, David; van Batenburg, F H D; Gultyaev, Alexander P; Leung, Ming-Ying

    2009-01-01

    Pseudoknots have been recognized to be an important type of RNA secondary structures responsible for many biological functions. PseudoBase, a widely used database of pseudoknot secondary structures developed at Leiden University, contains over 250 records of pseudoknots obtained in the past 25 years through crystallography, NMR, mutational experiments and sequence comparisons. To promptly address the growing analysis requests of the researchers on RNA structures and bring together information from multiple sources across the Internet to a single platform, we designed and implemented PseudoBase++, an extension of PseudoBase for easy searching, formatting and visualization of pseudoknots. PseudoBase++ (http://pseudobaseplusplus.utep.edu) maps the PseudoBase dataset into a searchable relational database including additional functionalities such as pseudoknot type. PseudoBase++ links each pseudoknot in PseudoBase to the GenBank record of the corresponding nucleotide sequence and allows scientists to automatically visualize RNA secondary structures with PseudoViewer. It also includes the capabilities of fine-grained reference searching and collecting new pseudoknot information.

  16. What are the personal and professional characteristics that distinguish the researchers who publish in high- and low-impact journals? A multi-national web-based survey

    PubMed Central

    Paiva, Carlos Eduardo; Araujo, Raphael L C; Paiva, Bianca Sakamoto Ribeiro; de Pádua Souza, Cristiano; Cárcano, Flavio Mavignier; Costa, Marina Moreira; Serrano, Sérgio Vicente; Lima, João Paulo Nogueira

    2017-01-01

    Purpose This study identifies the personal and professional profiles of researchers with a greater potential to publish high-impact academic articles. Method The study involved conducting an international survey of journal authors using a web-based questionnaire. The survey examined personal characteristics, funding, and the perceived barriers of research quality, work-life balance, and satisfaction and motivation in relation to career. The processes of manuscript writing and journal publication were measured using an online questionnaire that was developed for this study. The responses were compared between the two groups of researchers using logistic regression models. Results A total of 269 questionnaires were analysed. The researchers shared some common perceptions; both groups reported that they were seeking recognition (or to be leaders in their areas) rather than financial remuneration. Furthermore, both groups identified time and funding constraints as the main obstacles to their scientific activities. The amount of time that was spent on research activities, having >5 graduate students under supervision, never using text editing services prior to the publication of articles, and living in a developed and English-speaking country were the independent variables that were associated with their article getting a greater chance of publishing in a high-impact journal. In contrast, using one’s own resources to perform studies decreased the chance of publishing in high-impact journals. Conclusions The researchers who publish in high-impact journals have distinct profiles compared with the researchers who publish in low-impact journals. English language abilities and the actual amount of time that is dedicated to research and scientific writing, as well as aspects that relate to the availability of financial resources are the factors that are associated with a successful researcher’s profile. PMID:28194230

  17. Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on In Silico Modeling of Published Data.

    PubMed

    Shin, Ga Hee; Kang, Byeong-Chul; Jang, Dai Ja

    2016-12-01

    Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion, fermented seafood (Jeotgal), and salt. The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. Red pepper inhibits decay due to microorganisms and prevents food from spoiling. The vast amount of biological information generated by academic and industrial research groups is reflected in a rapidly growing body of scientific literature and expanding data resources. However, the genome, biological pathway, and related disease data are insufficient to explain the health benefits of kimchi because of the varied and heterogeneous data types. Therefore, we have constructed an appropriate semantic data model based on an integrated food knowledge database and analyzed the functional and biological processes associated with kimchi in silico. This complex semantic network of several entities and connections was generalized to answer complex questions, and we demonstrated how specific disease pathways are related to kimchi consumption.

  18. Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on In Silico Modeling of Published Data

    PubMed Central

    Shin, Ga Hee; Kang, Byeong-Chul

    2016-01-01

    Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion, fermented seafood (Jeotgal), and salt. The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. Red pepper inhibits decay due to microorganisms and prevents food from spoiling. The vast amount of biological information generated by academic and industrial research groups is reflected in a rapidly growing body of scientific literature and expanding data resources. However, the genome, biological pathway, and related disease data are insufficient to explain the health benefits of kimchi because of the varied and heterogeneous data types. Therefore, we have constructed an appropriate semantic data model based on an integrated food knowledge database and analyzed the functional and biological processes associated with kimchi in silico. This complex semantic network of several entities and connections was generalized to answer complex questions, and we demonstrated how specific disease pathways are related to kimchi consumption. PMID:28154515

  19. PUBLISHER'S ANNOUNCEMENT: Refereeing standards

    NASA Astrophysics Data System (ADS)

    Bender, C.; Scriven, N.

    2004-08-01

    submitting papers to J. Phys. A. In addition to the office staff, the journal has two assets of enormous value. First, there is the pool of referees. It is impossible to have an academic system based on publication of original ideas without peer review. I believe that when one submits papers for publication in journals, one assumes a moral responsibility to participate in the peer review system. A published author has an obligation to referee papers and thereby to keep the scientific quality of published work as high as possible. In general, referees' reports that are submitted to scientific journals vary in quality. Some referees reply quickly and write detailed, careful, and helpful reports; other referees write cursory reports that are not so useful. Over the years J. Phys. A has amassed an amazingly talented and sedulous group of referees. I thank the referees of the journal who have worked so hard and have contributed their time without any expectation of financial compensation. I emphasize that the office tries hard to avoid overburdening referees. Sending back a quick and detailed response does not increase the likelihood of the referee receiving another paper to evaluate. (A number of people have told me that they sit on and delay the refereeing of papers in hopes of reducing the number of papers per year that they receive to referee. The office at J. Phys. A works to make this sort of strategy unnecessary.) The second asset is the Board of Editors and the Advisory Panel. For some journals membership on the Board of Editors is a sinecure. However, the 37 members of the Board of Editors and the 50 members of the Advisory Panel of J. Phys. A have been chosen not only because they are distinguished mathematical physicists but also because of their demonstrated willingness to work hard. Six members of the Board of Editors are designated as Section Editors: H Nishimori, Tokyo Institute of Technology, Japan (Statistical Physics); P Grassberger, Bergische Universität GH

  20. ERTS-1 MSS imagery: Its use in delineating soil associations and as a base map for publishing soils information. [South Dakota

    NASA Technical Reports Server (NTRS)

    Westin, F. C.

    1974-01-01

    ERTS 1 imagery is a useful tool in the identification and refinement of soil association areas and an excellent base map upon which soil association information can be published. Prints of bands 5 and 7 were found to be most useful to help delineate major soil and vegetation areas. After delineating major soil areas, over 4800 land sale prices covering a period of 1967-72 were located in the soil areas and averaged. The soil association then were described as soil association value areas and published on a 1:1,000,000 scale ERTS mosaic of South Dakota constructed using negative prints of band 7. The map is intended for use by state and county revenue officers, by individual buyers and sellers of land and lending institutions, and as a reference map by those planning road routes and cable lines and pipelines.

  1. A simple heuristic for Internet-based evidence search in primary care: a randomized controlled trial

    PubMed Central

    Eberbach, Andreas; Becker, Annette; Rochon, Justine; Finkemeler, Holger; Wagner, Achim; Donner-Banzhoff, Norbert

    2016-01-01

    Background General practitioners (GPs) are confronted with a wide variety of clinical questions, many of which remain unanswered. Methods In order to assist GPs in finding quick, evidence-based answers, we developed a learning program (LP) with a short interactive workshop based on a simple three-step-heuristic to improve their search and appraisal competence (SAC). We evaluated the LP effectiveness with a randomized controlled trial (RCT). Participants (intervention group [IG] n=20; control group [CG] n=31) rated acceptance and satisfaction and also answered 39 knowledge questions to assess their SAC. We controlled for previous knowledge in content areas covered by the test. Results Main outcome – SAC: within both groups, the pre–post test shows significant (P=0.00) improvements in correctness (IG 15% vs CG 11%) and confidence (32% vs 26%) to find evidence-based answers. However, the SAC difference was not significant in the RCT. Other measures Most workshop participants rated “learning atmosphere” (90%), “skills acquired” (90%), and “relevancy to my practice” (86%) as good or very good. The LP-recommendations were implemented by 67% of the IG, whereas 15% of the CG already conformed to LP recommendations spontaneously (odds ratio 9.6, P=0.00). After literature search, the IG showed a (not significantly) higher satisfaction regarding “time spent” (IG 80% vs CG 65%), “quality of information” (65% vs 54%), and “amount of information” (53% vs 47%). Conclusion Long-standing established GPs have a good SAC. Despite high acceptance, strong learning effects, positive search experience, and significant increase of SAC in the pre–post test, the RCT of our LP showed no significant difference in SAC between IG and CG. However, we suggest that our simple decision heuristic merits further investigation. PMID:27563264

  2. BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server.

    PubMed

    Xiong, Bing; Wu, Jie; Burk, David L; Xue, Mengzhu; Jiang, Hualiang; Shen, Jingkang

    2010-01-25

    Genome sequencing and post-genomics projects such as structural genomics are extending the frontier of the study of sequence-structure-function relationship of genes and their products. Although many sequence/structure-based methods have been devised with the aim of deciphering this delicate relationship, there still remain large gaps in this fundamental problem, which continuously drives researchers to develop novel methods to extract relevant information from sequences and structures and to infer the functions of newly identified genes by genomics technology. Here we present an ultrafast method, named BSSF(Binding Site Similarity & Function), which enables researchers to conduct similarity searches in a comprehensive three-dimensional binding site database extracted from PDB structures. This method utilizes a fingerprint representation of the binding site and a validated statistical Z-score function scheme to judge the similarity between the query and database items, even if their similarities are only constrained in a sub-pocket. This fingerprint based similarity measurement was also validated on a known binding site dataset by comparing with geometric hashing, which is a standard 3D similarity method. The comparison clearly demonstrated the utility of this ultrafast method. After conducting the database searching, the hit list is further analyzed to provide basic statistical information about the occurrences of Gene Ontology terms and Enzyme Commission numbers, which may benefit researchers by helping them to design further experiments to study the query proteins. This ultrafast web-based system will not only help researchers interested in drug design and structural genomics to identify similar binding sites, but also assist them by providing further analysis of hit list from database searching.

  3. Investigation of candidate data structures and search algorithms to support a knowledge based fault diagnosis system

    NASA Technical Reports Server (NTRS)

    Bosworth, Edward L., Jr.

    1987-01-01

    The focus of this research is the investigation of data structures and associated search algorithms for automated fault diagnosis of complex systems such as the Hubble Space Telescope. Such data structures and algorithms will form the basis of a more sophisticated Knowledge Based Fault Diagnosis System. As a part of the research, several prototypes were written in VAXLISP and implemented on one of the VAX-11/780's at the Marshall Space Flight Center. This report describes and gives the rationale for both the data structures and algorithms selected. A brief discussion of a user interface is also included.

  4. Fast orthogonal search method to estimate upper arm Hill-based muscle model parameters.

    PubMed

    Mountjoy, Katherine C; Hashtrudi-Zaad, Keyvan; Morin, Evelyn L

    2008-01-01

    We propose a methodology to estimate subject-specific physiological parameters of Hill-based models of upper arm muscles. The methodology uses Hill-type candidate functions in the Fast Orthogonal Search (FOS) method to predict force at the wrist during elbow flexion and extension. To this end, surface EMG data from three muscles of the upper arm were recorded from 5 subjects as they performed isometric contractions at different elbow joint angles. Estimated muscle activation level and joint angle were utilized as inputs to the FOS model to obtain subject-specific estimates of optimal joint angle the Gaussian shape parameter for the force-length relationship for each muscle.

  5. Improving Biomedical Signal Search Results in Big Data Case-Based Reasoning Environments.

    PubMed

    Woodbridge, Jonathan; Mortazavi, Bobak; Bui, Alex A T; Sarrafzadeh, Majid

    2016-06-01

    Time series subsequence matching has importance in a variety of areas in healthcare informatics. These include case-based diagnosis and treatment as well as discovery of trends among patients. However, few medical systems employ subsequence matching due to high computational and memory complexities. This manuscript proposes a randomized Monte Carlo sampling method to broaden search criteria with minimal increases in computational and memory complexities over R-NN indexing. Information gain improves while producing result sets that approximate the theoretical result space, query results increase by several orders of magnitude, and recall is improved with no signi cant degradation to precision over R-NN matching.

  6. A method of characterizing network topology based on the breadth-first search tree

    NASA Astrophysics Data System (ADS)

    Zhou, Bin; He, Zhe; Wang, Nianxin; Wang, Bing-Hong

    2016-05-01

    A method based on the breadth-first search tree is proposed in this paper to characterize the hierarchical structure of network. In this method, a similarity coefficient is defined to quantitatively distinguish networks, and quantitatively measure the topology stability of the network generated by a model. The applications of the method are discussed in ER random network, WS small-world network and BA scale-free network. The method will be helpful for deeply describing network topology and provide a starting point for researching the topology similarity and isomorphism of networks.

  7. A searching and reporting system for relational databases using a graph-based metadata representation.

    PubMed

    Hewitt, Robin; Gobbi, Alberto; Lee, Man-Ling

    2005-01-01

    Relational databases are the current standard for storing and retrieving data in the pharmaceutical and biotech industries. However, retrieving data from a relational database requires specialized knowledge of the database schema and of the SQL query language. At Anadys, we have developed an easy-to-use system for searching and reporting data in a relational database to support our drug discovery project teams. This system is fast and flexible and allows users to access all data without having to write SQL queries. This paper presents the hierarchical, graph-based metadata representation and SQL-construction methods that, together, are the basis of this system's capabilities.

  8. Color octet electron search potential of FCC based e–p colliders

    NASA Astrophysics Data System (ADS)

    Acar, Y. C.; Kaya, U.; Oner, B. B.; Sultansoy, S.

    2017-04-01

    Resonant production of color octet electrons, e 8, at the FCC based e–p colliders is analyzed. It is shown that e-FCC will cover much a wider region of e 8 masses compared to the LHC. Moreover, with the highest electron beam energy, the e 8 search potential of the e-FCC exceeds that of the FCC p–p collider. If e 8 is discovered earlier by the FCC p–p collider, e-FCC will give an opportunity to handle very important additional information. For example, the compositeness scale can be probed up to the hundreds of TeV region.

  9. Similarity searching for chest CT images based on object features and spatial relation maps.

    PubMed

    Yu, Sung-Nien; Chiang, Chih-Tsung

    2004-01-01

    In this paper, an object-based image retrieval system for chest CT image databases is proposed. Based on the scheme of the content-based image retrieval method, we proposed an image segmentation method which combines the anatomical knowledge of the chest and the well-known watershed segmentation algorithm. The purpose of segmentation is to identify the mediastinum and the two lung lobes in a chest CT image. The ARGs (attributed relational graphs) are chosen to describe the features of segmented objects. Then, image database is constructed by the feature vectors of images. In database searching, two searching modes are provided that are "query by example" and "query by object". Our system uses Euclidean distance to measure the similarity between the image in query and the image in database. The system output the 30 most similar images in the chest CT image database as query results. The experimental results show that the average precision of our system is about 80% which is impressive in a totally automatic medical image retrieval system. Moreover, query concentrated in certain objects features usually show better result than the regular query by example. The possible reasons are discussed.

  10. Exploring Multidisciplinary Data Sets through Database Driven Search Capabilities and Map-Based Web Services

    NASA Astrophysics Data System (ADS)

    O'Hara, S.; Ferrini, V.; Arko, R.; Carbotte, S. M.; Leung, A.; Bonczkowski, J.; Goodwillie, A.; Ryan, W. B.; Melkonian, A. K.

    2008-12-01

    Relational databases containing geospatially referenced data enable the construction of robust data access pathways that can be customized to suit the needs of a diverse user community. Web-based search capabilities driven by radio buttons and pull-down menus can be generated on-the-fly leveraging the power of the relational database and providing specialists a means of discovering specific data and data sets. While these data access pathways are sufficient for many scientists, map-based data exploration can also be an effective means of data discovery and integration by allowing users to rapidly assess the spatial co- registration of several data types. We present a summary of data access tools currently provided by the Marine Geoscience Data System (www.marine-geo.org) that are intended to serve a diverse community of users and promote data integration. Basic search capabilities allow users to discover data based on data type, device type, geographic region, research program, expedition parameters, personnel and references. In addition, web services are used to create database driven map interfaces that provide live access to metadata and data files.

  11. Speeding up tandem mass spectrometry-based database searching by longest common prefix

    PubMed Central

    2010-01-01

    Background Tandem mass spectrometry-based database searching has become an important technology for peptide and protein identification. One of the key challenges in database searching is the remarkable increase in computational demand, brought about by the expansion of protein databases, semi- or non-specific enzymatic digestion, post-translational modifications and other factors. Some software tools choose peptide indexing to accelerate processing. However, peptide indexing requires a large amount of time and space for construction, especially for the non-specific digestion. Additionally, it is not flexible to use. Results We developed an algorithm based on the longest common prefix (ABLCP) to efficiently organize a protein sequence database. The longest common prefix is a data structure that is always coupled to the suffix array. It eliminates redundant candidate peptides in databases and reduces the corresponding peptide-spectrum matching times, thereby decreasing the identification time. This algorithm is based on the property of the longest common prefix. Even enzymatic digestion poses a challenge to this property, but some adjustments can be made to this algorithm to ensure that no candidate peptides are omitted. Compared with peptide indexing, ABLCP requires much less time and space for construction and is subject to fewer restrictions. Conclusions The ABLCP algorithm can help to improve data analysis efficiency. A software tool implementing this algorithm is available at http://pfind.ict.ac.cn/pfind2dot5/index.htm PMID:21108792

  12. Image copy-move forgery detection based on polar cosine transform and approximate nearest neighbor searching.

    PubMed

    Li, Yuenan

    2013-01-10

    Copy-move is one of the most commonly used image tampering operation, where a part of image content is copied and then pasted to another part of the same image. In order to make the forgery visually convincing and conceal its trace, the copied part may subject to post-processing operations such as rotation and blur. In this paper, we propose a polar cosine transform and approximate nearest neighbor searching based copy-move forgery detection algorithm. The algorithm starts by dividing the image into overlapping patches. Robust and compact features are extracted from patches by taking advantage of the rotationally-invariant and orthogonal properties of the polar cosine transform. Potential copy-move pairs are then detected by identifying the patches with similar features, which is formulated as approximate nearest neighbor searching and accomplished by means of locality-sensitive hashing (LSH). Finally, post-verifications are performed on potential pairs to filter out false matches and improve the accuracy of forgery detection. To sum up, the LSH based similar patch identification and the post-verification methods are two major novelties of the proposed work. Experimental results reveal that the proposed work can produce accurate detection results, and it exhibits high robustness to various post-processing operations. In addition, the LSH based similar patch detection scheme is much more effective than the widely used lexicographical sorting.

  13. Awareness, attitudes, and perceptions of Croatian-based orthopedic and trauma surgeons toward scientific manuscripts, publishing internationally and medical writing. Results of an online questionnaire.

    PubMed

    De Faoite, Diarmuid; Bakota, Bore; Staresinić, Mario; Kopljar, Mario; Cvjetko, Ivan; Dobrić, Ivan

    2013-03-01

    The objective of this survey was to identify the importance placed by Croatian-based surgeons on writing scientific manuscripts and publishing them internationally, as well as their awareness of and attitudes toward medical writing. A link to an online survey was sent to 327 Croatian-based orthopedic and trauma surgeons. The electronic questionnaire consisted of rating scales, multiple choice questions and free text reply boxes. A total of 61 surgeons based in Croatia replied to the survey, yielding a response rate of 19% (61/327). The survey results indicate that surgeons in Croatia are active in both research and the writing of manuscripts. There is also a high level of interest among them to publish internationally in English to further their careers. While 68% (38/56) of respondents initially claimed to know about medical writing, further questioning on the subject revealed a reduced level of familiarity with the concept. Only 19% (11/58) of respondents had ever engaged the services of a medical writer and they were generally satisfied with the work done across the three areas of language, editing and scientific knowledge. Medical writers are advised to increase awareness of their services among Croatian-based orthopedic and trauma surgeons who may well have a need for their expertise.

  14. Search and retrieval of office files using dBASE 3

    NASA Technical Reports Server (NTRS)

    Breazeale, W. L.; Talley, C. R.

    1986-01-01

    Described is a method of automating the office files retrieval process using a commercially available software package (dBASE III). The resulting product is a menu-driven computer program which requires no computer skills to operate. One part of the document is written for the potential user who has minimal computer experience and uses sample menu screens to explain the program; while a second part is oriented towards the computer literate individual and includes rather detailed descriptions of the methodology and search routines. Although much of the programming techniques are explained, this document is not intended to be a tutorial on dBASE III. It is hoped that the document will serve as a stimulus for other applications of dBASE III.

  15. Ligand-Based Virtual Screening in a Search for Novel Anti-HIV-1 Chemotypes.

    PubMed

    Kurczyk, Agata; Warszycki, Dawid; Musiol, Robert; Kafel, Rafał; Bojarski, Andrzej J; Polanski, Jaroslaw

    2015-10-26

    In a search for new anti-HIV-1 chemotypes, we developed a multistep ligand-based virtual screening (VS) protocol combining machine learning (ML) methods with the privileged structures (PS) concept. In its learning step, the VS protocol was based on HIV integrase (IN) inhibitors fetched from the ChEMBL database. The performances of various ML methods and PS weighting scheme were evaluated and applied as VS filtering criteria. Finally, a database of 1.5 million commercially available compounds was virtually screened using a multistep ligand-based cascade, and 13 selected unique structures were tested by measuring the inhibition of HIV replication in infected cells. This approach resulted in the discovery of two novel chemotypes with moderate antiretroviral activity, that, together with their topological diversity, make them good candidates as lead structures for future optimization.

  16. The ship-borne infrared searching and tracking system based on the inertial platform

    NASA Astrophysics Data System (ADS)

    Li, Yan; Zhang, Haibo

    2011-08-01

    As a result of the radar system got interferenced or in the state of half silent ,it can cause the guided precision drop badly In the modern electronic warfare, therefore it can lead to the equipment depended on electronic guidance cannot strike the incoming goals exactly. It will need to rely on optoelectronic devices to make up for its shortcomings, but when interference is in the process of radar leading ,especially the electro-optical equipment is influenced by the roll, pitch and yaw rotation ,it can affect the target appear outside of the field of optoelectronic devices for a long time, so the infrared optoelectronic equipment can not exert the superiority, and also it cannot get across weapon-control system "reverse bring" missile against incoming goals. So the conventional ship-borne infrared system unable to track the target of incoming quickly , the ability of optoelectronic rivalry declines heavily.Here we provide a brand new controlling algorithm for the semi-automatic searching and infrared tracking based on inertial navigation platform. Now it is applying well in our XX infrared optoelectronic searching and tracking system. The algorithm is mainly divided into two steps: The artificial mode turns into auto-searching when the deviation of guide exceeds the current scene under the course of leading for radar.When the threshold value of the image picked-up is satisfied by the contrast of the target in the searching scene, the speed computed by using the CA model Least Square Method feeds back to the speed loop. And then combine the infrared information to accomplish the closed-loop control of the infrared optoelectronic system tracking. The algorithm is verified via experiment. Target capturing distance is 22.3 kilometers on the great lead deviation by using the algorithm. But without using the algorithm the capturing distance declines 12 kilometers. The algorithm advances the ability of infrared optoelectronic rivalry and declines the target capturing

  17. Search for exotic particles at CDF

    SciTech Connect

    Gold, M.S.

    1992-10-01

    We have searched for exotic particles in p[bar p] collisions at 1.8 TeV in data taken with the Collider Detector at Fermilab. We review our published limits on W[prime] and Z[prime] masses, and on the scale of lepton-quark compositeness. We also report preliminary mass limits based on searches for leptoquarks, supersymmetric quarks and gluons, and exotic, stable colored fermions.

  18. SVG-Based Web Publishing

    NASA Astrophysics Data System (ADS)

    Gao, Jerry Z.; Zhu, Eugene; Shim, Simon

    2003-01-01

    With the increasing applications of the Web in e-commerce, advertising, and publication, new technologies are needed to improve Web graphics technology due to the current limitation of technology. The SVG (Scalable Vector Graphics) technology is a new revolutionary solution to overcome the existing problems in the current web technology. It provides precise and high-resolution web graphics using plain text format commands. It sets a new standard for web graphic format to allow us to present complicated graphics with rich test fonts and colors, high printing quality, and dynamic layout capabilities. This paper provides a tutorial overview about SVG technology and its essential features, capability, and advantages. The reports a comparison studies between SVG and other web graphics technologies.

  19. Development of a PubMed Based Search Tool for Identifying Sex and Gender Specific Health Literature

    PubMed Central

    Song, Michael M.; Simonsen, Cheryl K.; Wilson, Joanna D.

    2016-01-01

    Abstract Background: An effective literature search strategy is critical to achieving the aims of Sex and Gender Specific Health (SGSH): to understand sex and gender differences through research and to effectively incorporate the new knowledge into the clinical decision making process to benefit both male and female patients. The goal of this project was to develop and validate an SGSH literature search tool that is readily and freely available to clinical researchers and practitioners. Methods: PubMed, a freely available search engine for the Medline database, was selected as the platform to build the SGSH literature search tool. Combinations of Medical Subject Heading terms, text words, and title words were evaluated for optimal specificity and sensitivity. The search tool was then validated against reference bases compiled for two disease states, diabetes and stroke. Results: Key sex and gender terms and limits were bundled to create a search tool to facilitate PubMed SGSH literature searches. During validation, the search tool retrieved 50 of 94 (53.2%) stroke and 62 of 95 (65.3%) diabetes reference articles selected for validation. A general keyword search of stroke or diabetes combined with sex difference retrieved 33 of 94 (35.1%) stroke and 22 of 95 (23.2%) diabetes reference base articles, with lower sensitivity and specificity for SGSH content. Conclusions: The Texas Tech University Health Sciences Center SGSH PubMed Search Tool provides higher sensitivity and specificity to sex and gender specific health literature. The tool will facilitate research, clinical decision-making, and guideline development relevant to SGSH. PMID:26555409

  20. Development of a PubMed Based Search Tool for Identifying Sex and Gender Specific Health Literature.

    PubMed

    Song, Michael M; Simonsen, Cheryl K; Wilson, Joanna D; Jenkins, Marjorie R

    2016-02-01

    An effective literature search strategy is critical to achieving the aims of Sex and Gender Specific Health (SGSH): to understand sex and gender differences through research and to effectively incorporate the new knowledge into the clinical decision making process to benefit both male and female patients. The goal of this project was to develop and validate an SGSH literature search tool that is readily and freely available to clinical researchers and practitioners. PubMed, a freely available search engine for the Medline database, was selected as the platform to build the SGSH literature search tool. Combinations of Medical Subject Heading terms, text words, and title words were evaluated for optimal specificity and sensitivity. The search tool was then validated against reference bases compiled for two disease states, diabetes and stroke. Key sex and gender terms and limits were bundled to create a search tool to facilitate PubMed SGSH literature searches. During validation, the search tool retrieved 50 of 94 (53.2%) stroke and 62 of 95 (65.3%) diabetes reference articles selected for validation. A general keyword search of stroke or diabetes combined with sex difference retrieved 33 of 94 (35.1%) stroke and 22 of 95 (23.2%) diabetes reference base articles, with lower sensitivity and specificity for SGSH content. The Texas Tech University Health Sciences Center SGSH PubMed Search Tool provides higher sensitivity and specificity to sex and gender specific health literature. The tool will facilitate research, clinical decision-making, and guideline development relevant to SGSH.