Evaluation of Safe Kids Week 2004: age 4 to 9? It's booster seat time!

PubMed

Howard, A; Beben, N; Rothman, L; Fiissel, D; MacArthur, C

2006-10-01

To assess the effectiveness of a national one week media campaign promoting booster seat use. Pre-test, post-test design based on nationally representative random digit dialing telephone survey, with control for exposure to campaign. Canada. Parents of children aged 4-9 years. During a one week campaign in May 2004, information on booster seat use was distributed via a national media campaign, retail stores, medical clinics, and community events. Information included pamphlets with guidelines for booster seat use, as well as a growth chart (designed by Safe Kids Canada) to assist parents in determining if their child should be using a booster seat. Assessing seat belt fit was described in detail on the growth chart. Knowledge, attitudes, and self-reported behaviors regarding booster seat use. Respondents in the group exposed to the campaign were twice as likely to report using a booster seat with lap and shoulder belt for their child (47%), compared to those in the pre-test (24%) and the unexposed (23%) groups (p<0.001). However, only small differences in general knowledge regarding booster seat use were found between the groups. A one week national media campaign substantially increased self-reported use of booster seats. Parents did not remember details of the campaign content, but did remember implications for their own child.

Clinical and economic assessment of different general population strategies of pertussis vaccine booster regarding number of doses and age of application for reducing whooping cough disease burden: a systematic review.

PubMed

Rodríguez-Cobo, Iria; Chen, Yen-Fu; Olowokure, Babatunde; Litchfield, Ian

2008-12-09

Pertussis continues to be an important cause of morbidity and mortality in children too young to be fully protected despite high vaccination coverage. This has been attributed to waning immunity in older people, leading to the development of strategies to increase levels of immunity. A systematic review was conducted to assess the clinical and cost effectiveness of four population-based strategies for pertussis booster vaccination: single booster at 12-24 months old, single pre-school booster, single adolescent booster and multiple boosters in adulthood every 10 years. Electronic databases and Internet resources were searched to June 2006. Nine observational studies, four mathematical models and eight economic evaluations were included, evaluating four different strategies. Strong evidence to recommend any of these strategies was not found.

Space shuttle booster multi-engine base flow analysis

NASA Technical Reports Server (NTRS)

Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

1972-01-01

A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

Exercise, manual therapy, and use of booster sessions in physical therapy for knee osteoarthritis: a multi-center, factorial randomized clinical trial.

PubMed

Fitzgerald, G K; Fritz, J M; Childs, J D; Brennan, G P; Talisa, V; Gil, A B; Neilson, B D; Abbott, J H

2016-08-01

(1) Do treatment effects differ between participants receiving manual therapy (MT) with exercise compared to subjects who don't, (2) are treatment effects sustained better when participants receive booster sessions compared to those who don't over a one year period in subjects with knee osteoarthritis (KOA)? Multi-center, 2 × 2 factorial randomized clinical trial. 300 participants with knee OA were randomized to four groups: exercise-no boosters (Ex), exercise-with boosters (Ex+B), manual therapy+exercise-no boosters (MT+Ex), manual therapy+exercise-with boosters (MT+Ex+B). The primary outcome was the Western Ontario and McMaster osteoarthritis index (WOMAC) at 1 year. Secondary outcomes included knee pain, physical performance tests, and proportions of participants meeting treatment responder criteria. There were no differences between groups on the WOMAC at 1 year or on any performance-based measures. Secondary analyses indicated a) better scores on the WOMAC and greater odds of being a treatment responder at 9 weeks for participants receiving MT, b) greater odds of being a treatment responder at 1 year for participants receiving boosters. Exploratory interaction analysis suggested knee pain decreases for participants receiving boosters and increases for participants not receiving boosters from 9 weeks to 1 year. MT or use of boosters with exercise did not result in additive improvement in the primary outcome at 1 year. Secondary outcomes suggest MT may have some short term benefit, and booster sessions may improve responder status and knee pain at 1 year. However, the role of booster sessions remains unclear in sustaining treatment effects and warrants further study. gov (NCT01314183). Copyright © 2016 Osteoarthritis Research Society International. All rights reserved.

Carpooling and booster seats: a national survey of parents.

PubMed

Macy, Michelle L; Clark, Sarah J; Freed, Gary L; Butchart, Amy T; Singer, Dianne C; Sasson, Comilla; Meurer, William J; Davis, Matthew M

2012-02-01

Booster seat use among school-aged children has been consistently lower than national goals. In this study, we sought to explore associations between parental experiences with booster seats and carpooling. We conducted a cross-sectional Web-based survey of a nationally representative panel of US parents in January 2010. As part of a larger survey, parents of 4- to 8-year-old children responded to 12 questions related to booster seats and carpooling. Of 1612 parents responding to the full survey (response rate = 71%), 706 had a 4- to 8-year-old child and 681 met inclusion rules. Most parents (76%) reported their child used a safety seat when riding in the family car. Of children reported to use seat belts, 74% did so in accordance with their state law. Parent report of child safety seat use was associated with younger child age and with the presence of state booster seat laws. Sixty-four percent of parents carpool. Among parents who carpool and whose children use a child safety seat: 79% indicated they would always ask another driver to use a booster seat for their child and 55% reported they always have their child use their booster seat when driving friends who do not have boosters. Carpooling is a common driving situation during which booster seat use is inconsistent. Social norms and self-efficacy are associated with booster seat use. Clinicians who care for children should increase efforts to convey the importance of using the size-appropriate restraint for every child on every trip.

Evaluation of Safe Kids Week 2004: Age 4 to 9? It's Booster Seat Time!

PubMed Central

Howard, A; Beben, N; Rothman, L; Fiissel, D; MacArthur, C

2006-01-01

Objective To assess the effectiveness of a national one week media campaign promoting booster seat use. Design Pre‐test, post‐test design based on nationally representative random digit dialing telephone survey, with control for exposure to campaign. Setting Canada. Subjects Parents of children aged 4–9 years. Interventions During a one week campaign in May 2004, information on booster seat use was distributed via a national media campaign, retail stores, medical clinics, and community events. Information included pamphlets with guidelines for booster seat use, as well as a growth chart (designed by Safe Kids Canada) to assist parents in determining if their child should be using a booster seat. Assessing seat belt fit was described in detail on the growth chart. Main outcome measures Knowledge, attitudes, and self‐reported behaviors regarding booster seat use. Results Respondents in the group exposed to the campaign were twice as likely to report using a booster seat with lap and shoulder belt for their child (47%), compared to those in the pre‐test (24%) and the unexposed (23%) groups (p<0.001). However, only small differences in general knowledge regarding booster seat use were found between the groups. Conclusions A one week national media campaign substantially increased self‐reported use of booster seats. Parents did not remember details of the campaign content, but did remember implications for their own child. PMID:17018673

Promoting booster seat use for young children: A school-based intervention pilot study

PubMed Central

Mundle, Kim; Cramm, Camille F.; Williams, Devon P.

2017-01-01

Abstract Purpose: Misuse and/or lack of booster seat use are often associated with high rates of injury and death among school-aged children. This pilot study examined the efficacy and the potential effectiveness of a booster seat intervention in the classroom. Methods: Two elementary schools participated (randomly assigned as one intervention school and one control school). At the intervention school, a certified car seat specialist and a police officer held an interactive booster seat session. The height and age for each child were recorded. Children received a certificate indicating whether they met the requirements for booster seat use and a postcard with car seat restraint specifications. Children in the control school received a brochure on car seat safety. Pre- and post-intervention self-reports were collected and booster seat use was observed. Results: Observational findings showed a decline in booster seat use at the control school and an increase in use at the intervention school. Self-reports of booster seat use indicated a decline at both schools; however, cell sizes were too small to permit statistical analyses. Conclusion: Anecdotally researchers found the sessions were easy to conduct and were well received by the children and could be easily integrated into programming in schools. Classroom sessions may have the potential to positively influence booster seat use among 6- to 8-year-olds. PMID:29479188

Analysis of quasi-hybrid solid rocket booster concepts for advanced earth-to-orbit vehicles

NASA Technical Reports Server (NTRS)

Zurawski, Robert L.; Rapp, Douglas C.

1987-01-01

A study was conducted to assess the feasibility of quasi-hybrid solid rocket boosters for advanced Earth-to-orbit vehicles. Thermochemical calculations were conducted to determine the effect of liquid hydrogen addition, solids composition change plus liquid hydrogen addition, and the addition of an aluminum/liquid hydrogen slurry on the theoretical performance of a PBAN solid propellant rocket. The space shuttle solid rocket booster was used as a reference point. All three quasi-hybrid systems theoretically offer higher specific impulse when compared with the space shuttle solid rocket boosters. However, based on operational and safety considerations, the quasi-hybrid rocket is not a practical choice for near-term Earth-to-orbit booster applications. Safety and technology issues pertinent to quasi-hybrid rocket systems are discussed.

Solid Rocket Booster Hydraulic Pump Port Cap Joint Load Testing

NASA Technical Reports Server (NTRS)

Gamwell, W. R.; Murphy, N. C.

2004-01-01

The solid rocket booster uses hydraulic pumps fabricated from cast C355 aluminum alloy, with 17-4 PH stainless steel pump port caps. Corrosion-resistant steel, MS51830 CA204L self-locking screw thread inserts are installed into C355 pump housings, with A286 stainless steel fasteners installed into the insert to secure the pump port cap to the housing. In the past, pump port cap fasteners were installed to a torque of 33 Nm (300 in-lb). However, the structural analyses used a significantly higher nut factor than indicated during tests conducted by Boeing Space Systems. When the torque values were reassessed using Boeing's nut factor, the fastener preload had a factor of safety of less than 1, with potential for overloading the joint. This paper describes how behavior was determined for a preloaded joint with a steel bolt threaded into steel inserts in aluminum parts. Finite element models were compared with test results. For all initial bolt preloads, bolt loads increased as external applied loads increased. For higher initial bolt preloads, less load was transferred into the bolt, due to external applied loading. Lower torque limits were established for pump port cap fasteners and additional limits were placed on insert axial deformation under operating conditions after seating the insert with an initial preload.

Space shuttle: Aerodynamic characteristics of a composite booster/040A orbiter launch configuration with fin and booster body configuration effect contribution

NASA Technical Reports Server (NTRS)

Ainsworth, R. W.; Johnson, J. C.; Watts, L. L.

1972-01-01

An investigation was made of the fin configuration and booster body configuration effects on a composite booster/040A orbiter launch configuration. Aerodynamic performance and stability characteristics in pitch and yaw were obtained. Configurations tested included two stepped cylindrical bodies of different lengths with a conical nose, four fin shapes of various sizes and aspect ratios mounted in different positions around the base of the bodies, two base flare angles and three 040A orbiter configurations. The orbiter variations included a tailless configuration and two tail sizes. A tailless booster launch configuration with deflected petals (expanded flare sectors) was also tested. The model scale was 0.003366. Data were converted to coefficient form in near real time, punched on cards, and tabulated. The cards used in conjunction with a Benson-Lehner plotter were used to provide plotted data. At the end of the test, tabulated input forms were completed for the SADSAC computer program to aid in publishing the final test data report.

Space Launch System Booster Separation Aerodynamic Database Development and Uncertainty Quantification

NASA Technical Reports Server (NTRS)

Chan, David T.; Pinier, Jeremy T.; Wilcox, Floyd J., Jr.; Dalle, Derek J.; Rogers, Stuart E.; Gomez, Reynaldo J.

2016-01-01

The development of the aerodynamic database for the Space Launch System (SLS) booster separation environment has presented many challenges because of the complex physics of the ow around three independent bodies due to proximity e ects and jet inter- actions from the booster separation motors and the core stage engines. This aerodynamic environment is dicult to simulate in a wind tunnel experiment and also dicult to simu- late with computational uid dynamics. The database is further complicated by the high dimensionality of the independent variable space, which includes the orientation of the core stage, the relative positions and orientations of the solid rocket boosters, and the thrust lev- els of the various engines. Moreover, the clearance between the core stage and the boosters during the separation event is sensitive to the aerodynamic uncertainties of the database. This paper will present the development process for Version 3 of the SLS booster separa- tion aerodynamic database and the statistics-based uncertainty quanti cation process for the database.

Does a booster intervention augment the preventive effects of an abbreviated version of the coping power program for aggressive children?

PubMed

Lochman, John E; Baden, Rachel E; Boxmeyer, Caroline L; Powell, Nicole P; Qu, Lixin; Salekin, Karen L; Windle, Michel

2014-01-01

Booster interventions have been presumed to be important methods for maintaining the effects of evidence-based programs for children with behavioral problems, but there has been remarkably little empirical attention to this assumption. The present study examines the effect of a child-oriented booster preventive intervention with children who had previously received an abbreviated version (24 child sessions, 10 parent sessions) of the Coping Power targeted prevention program. Two hundred and forty-one children (152 boys, 89 girls) were screened as having moderate to high levels of aggressive behavior in 4th grade, then half were randomly assigned to receive the abbreviated Coping Power program in 5th grade, and half of the preventive intervention children were then randomly assigned to a Booster condition in 6th grade. The Booster sessions consisted of brief monthly individual contacts, and were primarily with the children. Five assessments across 4 years were collected from teachers, providing a three-year follow-up for all children who participated in the project. Results indicated that the abbreviated Coping Power program (one-third shorter than the full intervention) had long-term effects in reducing children's externalizing problem behaviors, proactive and reactive aggression, impulsivity traits and callous-unemotional traits. The Booster intervention did not augment these prevention effects. These findings indicate that a briefer and more readily disseminated form of an evidence-based targeted preventive intervention was effective. The findings have potential implications for policy and guidelines about possible intervention length and booster interventions.

Does a Booster Intervention Augment the Preventive Effects of an Abbreviated Version of the Coping Power Program for Aggressive Children?

PubMed Central

Lochman, John E.; Baden, Rachel E.; Boxmeyer, Caroline L.; Powell, Nicole P.; Qu, Lixin; Salekin, Karen L.; Windle, Michel

2013-01-01

Booster interventions have been presumed to be important methods for maintaining the effects of evidence-based programs for children with behavioral problems, but there has been remarkably little empirical attention to this assumption. The present study examines the effect of a child-oriented booster preventive intervention with children who had previously received an abbreviated version (24 child sessions, 10 parent sessions) of the Coping Power targeted prevention program. Two hundred and forty-one children (152 boys, 89 girls) were screened as having moderate to high levels of aggressive behavior in 4th grade, then half were randomly assigned to receive the abbreviated Coping Power program in 5th grade, and half of the preventive intervention children were then randomly assigned to a Booster condition in 6th grade. The Booster sessions consisted of brief monthly individual contacts, and were primarily with the children. Five assessments across four years were collected from teachers, providing a three-year follow-up for all children who participated in the project. Results indicated that the abbreviated Coping Power program (one-third shorter than the full intervention) had long-term effects in reducing children’s externalizing problem behaviors, proactive and reactive aggression, impulsivity traits and callous-unemotional traits. The Booster intervention did not augment these prevention effects. These findings indicate that a briefer and more readily disseminated form of an evidence-based targeted preventive intervention was effective. The findings have potential implications for policy and guidelines about possible intervention length and booster interventions. PMID:23417235

Integrated hydraulic booster/tool string technology for unfreezing of stuck downhole strings in horizontal wells

NASA Astrophysics Data System (ADS)

Tian, Q. Z.

2017-12-01

It is common to use a jarring tool to unfreeze stuck downhole string. However, in a horizontal well, influenced by the friction caused by the deviated section, jarring effect is poor; on the other hand, the forcing point can be located in the horizontal section by a hydraulic booster and the friction can be reduced, but it is time-consuming and easy to break downhole string using a large-tonnage and constant pull force. A hydraulic booster - jar tool string has been developed for unfreezing operation in horizontal wells. The technical solution involves three elements: a two-stage parallel spring cylinder structure for increasing the energy storage capacity of spring accelerators; multiple groups of spring accelerators connected in series to increase the working stroke; a hydraulic booster intensifying jarring force. The integrated unfreezing tool string based on these three elements can effectively overcome the friction caused by a deviated borehole, and thus unfreeze a stuck string with the interaction of the hydraulic booster and the mechanical jar which form an alternatively dynamic load. Experimental results show that the jarring performance parameters of the hydraulic booster-jar unfreezing tool string for the horizontal wells are in accordance with original design requirements. Then field technical parameters were developed based on numerical simulation and experimental data. Field application shows that the hydraulic booster-jar unfreezing tool string is effective to free stuck downhole tools in a horizontal well, and it reduces hook load by 80% and lessens the requirement of workover equipment. This provides a new technology to unfreeze stuck downhole string in a horizontal well.

104. SIGNAL CONDITIONERS FOR BOOSTER INSTRUMENTATION, SOUTHWEST SIDE OF LANDLINE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

104. SIGNAL CONDITIONERS FOR BOOSTER INSTRUMENTATION, SOUTHWEST SIDE OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

Lessons learned for follow-up phone booster counseling calls with substance abusing emergency department patients.

PubMed

Donovan, Dennis M; Hatch-Maillette, Mary A; Phares, Melissa M; McGarry, Ernest; Peavy, K Michelle; Taborsky, Julie

2015-03-01

Post-visit "booster" sessions have been recommended to augment the impact of brief interventions delivered in the emergency department (ED). This paper, which focuses on implementation issues, presents descriptive information and interventionists' qualitative perspectives on providing brief interventions over the phone, challenges, "lessons learned", and recommendations for others attempting to implement adjunctive booster calls. Attempts were made to complete two 20-minute telephone "booster" calls within a week following a patient's ED discharge with 425 patients who screened positive for and had recent problematic substance use other than alcohol or nicotine. Over half (56.2%) of participants completed the initial call; 66.9% of those who received the initial call also completed the second call. Median number of attempts to successfully contact participants for the first and second calls were 4 and 3, respectively. Each completed call lasted an average of about 22 minutes. Common challenges/barriers identified by booster callers included unstable housing, limited phone access, unavailability due to additional treatment, lack of compensation for booster calls, and booster calls coming from an area code different than the participants' locale and from someone other than ED staff. Specific recommendations are presented with respect to implementing a successful centralized adjunctive booster call system. Future use of booster calls might be informed by research on contingency management (e.g., incentivizing call completions), smoking cessation quitlines, and phone-based continuing care for substance abuse patients. Future research needs to evaluate the incremental benefit of adjunctive booster calls on outcomes over and above that of brief motivational interventions delivered in the ED setting. Copyright © 2015 Elsevier Inc. All rights reserved.

he second X-43A and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean

NASA Image and Video Library

2004-03-27

The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean on March 27, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif. Minutes later the X-43A separated from the Pegasus booster and accelerated to its intended speed of Mach 7.

Exercise, Manual Therapy, and Booster Sessions in Knee Osteoarthritis: Cost-Effectiveness Analysis From a Multicenter Randomized Controlled Trial.

PubMed

Bove, Allyn M; Smith, Kenneth J; Bise, Christopher G; Fritz, Julie M; Childs, John; Brennan, Gerard P; Abbott, J Haxby; Fitzgerald, G Kelley

2018-01-01

Limited information exists regarding the cost-effectiveness of rehabilitation strategies for individuals with knee osteoarthritis (OA). The study objective was to compare the cost-effectiveness of 4 different combinations of exercise, manual therapy, and booster sessions for individuals with knee OA. This economic evaluation involved a cost-effectiveness analysis performed alongside a multicenter randomized controlled trial. The study took place in Pittsburgh, Pennsylvania; Salt Lake City, Utah; and San Antonio, Texas. The study participants were 300 individuals taking part in a randomized controlled trial investigating various physical therapy strategies for knee OA. Participants were randomized into 4 treatment groups: exercise only (EX), exercise plus booster sessions (EX+B), exercise plus manual therapy (EX+MT), and exercise plus manual therapy and booster sessions (EX+MT+B). For the 2-year base case scenario, a Markov model was constructed using the United States societal perspective and a 3% discount rate for costs and quality-adjusted life years (QALYs). Incremental cost-effectiveness ratios were calculated to compare differences in cost per QALY gained among the 4 treatment strategies. In the 2-year analysis, booster strategies (EX+MT+B and EX+B) dominated no-booster strategies, with both lower health care costs and greater effectiveness. EX+MT+B had the lowest total health care costs. EX+B cost ${\\$}$1061 more and gained 0.082 more QALYs than EX+MT+B, for an incremental cost-effectiveness ratio of ${\\$}$12,900/QALY gained. The small number of total knee arthroplasty surgeries received by individuals in this study made the assessment of whether any particular strategy was more successful at delaying or preventing surgery in individuals with knee OA difficult. Spacing exercise-based physical therapy sessions over 12 months using periodic booster sessions was less costly and more effective over 2 years than strategies not containing booster sessions for individuals with knee OA. © 2017 American Physical Therapy Association

Hybrid Propulsion Technology Program

NASA Technical Reports Server (NTRS)

Jensen, G. E.; Holzman, A. L.

1990-01-01

Future launch systems of the United States will require improvements in booster safety, reliability, and cost. In order to increase payload capabilities, performance improvements are also desirable. The hybrid rocket motor (HRM) offers the potential for improvements in all of these areas. The designs are presented for two sizes of hybrid boosters, a large 4.57 m (180 in.) diameter booster duplicating the Advanced Solid Rocket Motor (ASRM) vacuum thrust-time profile and smaller 2.44 m (96 in.), one-quater thrust level booster. The large booster would be used in tandem, while eight small boosters would be used to achieve the same total thrust. These preliminary designs were generated as part of the NASA Hybrid Propulsion Technology Program. This program is the first phase of an eventual three-phaes program culminating in the demonstration of a large subscale engine. The initial trade and sizing studies resulted in preferred motor diameters, operating pressures, nozzle geometry, and fuel grain systems for both the large and small boosters. The data were then used for specific performance predictions in terms of payload and the definition and selection of the requirements for the major components: the oxidizer feed system, nozzle, and thrust vector system. All of the parametric studies were performed using realistic fuel regression models based upon specific experimental data.

Evaluation of give kids a boost: A school-based program to increase booster seat use among urban children in economically disadvantaged areas.

PubMed

Yellman, Merissa A; Rodriguez, Marissa A; Colunga, Maria Isabel; McCoy, Mary A; Stephens-Stidham, Shelli; Brown, L Steven; Istre, Gregory R

2018-05-19

This study evaluated the effectiveness of a series of 1-year multifaceted school-based programs aimed at increasing booster seat use among urban children 4-7 years of age in economically disadvantaged areas. During 4 consecutive school years, 2011-2015, the Give Kids a Boost (GKB) program was implemented in a total of 8 schools with similar demographics in Dallas County. Observational surveys were conducted at project schools before project implementation (P 0 ), 1-4 weeks after the completion of project implementation (P 1 ), and 4-5 months later (P 2 ). Changes in booster seat use for the 3 time periods were compared for the 8 project and 14 comparison schools that received no intervention using a nonrandomized trial process. The intervention included (1) train-the-trainer sessions with teachers and parents; (2) presentations about booster seat safety; (3) tailored communication to parents; (4) distribution of fact sheets/resources; (5) walk-around education; and (6) booster seat inspections. The association between the GKB intervention and proper booster seat use was determined initially using univariate analysis. The association was also estimated using a generalized linear mixed model predicting a binomial outcome (booster seat use) for those aged 4 to 7 years, adjusted for child-level variables (age, sex, race/ethnicity) and car-level variables (vehicle type). The model incorporated the effects of clustering by site and by collection date to account for the possibility of repeated sampling. In the 8 project schools, booster seat use for children 4-7 years of age increased an average of 20.9 percentage points between P 0 and P 1 (P 0 = 4.8%, P 1 = 25.7%; odds ratio [OR] = 6.9; 95% confidence interval [CI], 5.5, 8.7; P < .001) and remained at that level in the P 2 time period (P 2 = 25.7%; P < .001, for P 0 vs. P 2 ) in the univariate analysis. The 14 comparison schools had minimal change in booster seat use. The multivariable model showed that children at the project schools were significantly more likely to be properly restrained in a booster seat after the intervention (OR = 2.7; 95% CI, 2.2, 3.3) compared to the P 0 time period and compared to the comparison schools. Despite study limitations, the GKB program was positively associated with an increase in proper booster seat use for children 4-7 years of age in school settings among diverse populations in economically disadvantaged areas. These increases persisted into the following school year in a majority of the project schools. The GKB model may be a replicable strategy to increase booster seat use among school-age children in similar urban settings.

Design Optimization of Gas Generator Hybrid Propulsion Boosters

NASA Technical Reports Server (NTRS)

Weldon, Vincent; Phillips, Dwight; Fink, Larry

1990-01-01

A methodology used in support of a study for NASA/MSFC to optimize the design of gas generator hybrid propulsion booster for uprating the National Space Transportation System (NSTS) is presented. The objective was to compare alternative configurations for this booster approach, optimizing each candidate concept on different bases, in order to develop data for a trade table on which a final decision was based. The methodology is capable of processing a large number of independent and dependent variables, adjusting the overall subsystems characteristics to arrive at a best compromise integrated design to meet various specific optimization criteria subject to selected constraints. For each system considered, a detailed weight statement was generated along with preliminary cost and reliability estimates.

Healthy Team Healthy U: A Prospective Validation of an Evidence-Based Worksite Health Promotion and Wellness Platform.

PubMed

Goldberg, Linn; Lockwood, Chondra; Garg, Bharti; Kuehl, Kerry S

2015-01-01

To evaluate the effects of a research-tested, team-based health promotion and wellness program combined with digital technologies and implemented in a diverse worksite setting among hospital, clinic, and university employees. A prospective cohort study of employees completing biometrics and questionnaires before and after the initial 12-session wellness program and its 12-session booster, 1 year later. After both the initial intervention and booster, blood pressure and weight were reduced, with greater reductions among employees with pre-hypertension and hypertension and those with a body mass index ≥25. After both the initial intervention and booster, there was a significant increase in (1) daily intake of fruit and vegetable servings, (2) days/week of ≥30 min of exercise, (3) days/week of strength training, and (4) levels of moderately vigorous and vigorous daily physical activity. Self-reported indices of both depression and work-related stress were reduced, while participants reported increased happiness. Post booster, average sleep quality, and sleep duration increased among higher risk employees reporting ≤6 h of daily sleep. Employees reported receiving encouragement from co-workers to engage in healthful diet and physical activities, and exercised together more, and indicated that they would recommend the program to other employees. Longitudinal analysis revealed the durability of the initial intervention outcomes with further beneficial effects after the booster. A research tested, comprehensive team-based health promotion and wellness program, combined with digital technologies, improved employee health behaviors, mood, sleep, elements of co-worker cohesion, and biometrics among a diverse multi-site workforce. Positive program effects were durable, with enhanced results after the booster.

Pain Assessment and Management After a Knowledge Translation Booster Intervention.

PubMed

Stevens, Bonnie J; Yamada, Janet; Promislow, Sara; Barwick, Melanie; Pinard, Marie

2016-10-01

Inadequate pain treatment leaves hospitalized children vulnerable to immediate and long-term sequelae. A multidimensional knowledge translation intervention (ie, the Evidence-based Practice for Improving Quality [EPIQ]) improved pain assessment, management, and intensity outcomes in 16 units at 8 Canadian pediatric hospitals. The sustained effectiveness of EPIQ over time is unknown, however. The goals of this study were to determine the following: (1) sustainability of the impact of EPIQ on pain assessment, management, and intensity outcomes 12, 24, and 36 months after EPIQ; (2) effectiveness of a pain practice change booster (Booster) intervention to sustain EPIQ outcomes over time; and (3) influence of context on sustainability. A prospective, repeated measures, cluster randomized controlled trial was undertaken in the 16 EPIQ units, 12 months after EPIQ completion, to determine the effectiveness of a practice change booster (Booster) to sustain EPIQ outcomes. Generalized estimating equation models examined outcomes controlling for child and unit contextual factors. Outcomes achieved during EPIQ were sustained in the use of any pain assessment measure (P = .01) and a validated pain assessment measure in the EPIQ units (P = .02) up to 36 months after EPIQ. Statistically significant improvements in pain management practices persisted in EPIQ units; results varied across time. There were no significant differences in outcomes after implementation of the Booster between the Booster and Nonbooster groups. Improved pain assessment and management practices were sustained after EPIQ; however, the Booster did not seem to provide additional impact. Copyright © 2016 by the American Academy of Pediatrics.

Applying network analysis and Nebula (neighbor-edges based and unbiased leverage algorithm) to ToxCast data.

PubMed

Ye, Hao; Luo, Heng; Ng, Hui Wen; Meehan, Joe; Ge, Weigong; Tong, Weida; Hong, Huixiao

2016-01-01

ToxCast data have been used to develop models for predicting in vivo toxicity. To predict the in vivo toxicity of a new chemical using a ToxCast data based model, its ToxCast bioactivity data are needed but not normally available. The capability of predicting ToxCast bioactivity data is necessary to fully utilize ToxCast data in the risk assessment of chemicals. We aimed to understand and elucidate the relationships between the chemicals and bioactivity data of the assays in ToxCast and to develop a network analysis based method for predicting ToxCast bioactivity data. We conducted modularity analysis on a quantitative network constructed from ToxCast data to explore the relationships between the assays and chemicals. We further developed Nebula (neighbor-edges based and unbiased leverage algorithm) for predicting ToxCast bioactivity data. Modularity analysis on the network constructed from ToxCast data yielded seven modules. Assays and chemicals in the seven modules were distinct. Leave-one-out cross-validation yielded a Q(2) of 0.5416, indicating ToxCast bioactivity data can be predicted by Nebula. Prediction domain analysis showed some types of ToxCast assay data could be more reliably predicted by Nebula than others. Network analysis is a promising approach to understand ToxCast data. Nebula is an effective algorithm for predicting ToxCast bioactivity data, helping fully utilize ToxCast data in the risk assessment of chemicals. Published by Elsevier Ltd.

Child posture and shoulder belt fit during extended night-time traveling: an in-transit observational study.

PubMed

Forman, Jason L; Segui-Gomez, Maria; Ash, Joseph H; Lopez-Valdes, Francisco J

2011-01-01

Understanding pediatric occupant postures can help researchers indentify injury risk factors, and provide information for prospective injury prediction. This study sought to observe lateral head positions and shoulder belt fit among older child automobile occupants during a scenario likely to result in sleeping - extended travel during the night. An observational, volunteer, in-transit study was performed with 30 pediatric rear-seat passengers, ages 7 to 14. Each was restrained by a three-point seatbelt and was driven for seventy-five minutes at night. Ten subjects used a high-back booster seat, ten used a low-back booster seat, and ten used none (based on the subject height and weight). The subjects were recorded with a low-light video camera, and one frame was analyzed per each minute of video. The high-back booster group exhibited a statistically significant (p<0.05) decrease in the mean frequency of poor shoulder belt fit compared to the no-booster and low-back booster groups. The high-back booster group also exhibited statistically significant decreases in the 90(th) percentile of the absolute value of the relative lateral motion of the head. The low-back booster group did not result in statistically significant decreases in poor shoulder belt fit or lateral head motion compared to the no-booster group. These results are consistent with the presence of large lateral supports of the high-back booster which provided support to the head while sleeping, reducing voluntary lateral occupant motion and improving shoulder belt fit. Future work includes examining lap belt fit in-transit, and examining the effects of these observations on predicted injury risk.

Child Posture and Shoulder Belt Fit During Extended Night-Time Traveling: An In-Transit Observational Study.

PubMed Central

Forman, Jason L.; Segui-Gomez, Maria; Ash, Joseph H.; Lopez-Valdes, Francisco J.

2011-01-01

Understanding pediatric occupant postures can help researchers indentify injury risk factors, and provide information for prospective injury prediction. This study sought to observe lateral head positions and shoulder belt fit among older child automobile occupants during a scenario likely to result in sleeping - extended travel during the night. An observational, volunteer, in-transit study was performed with 30 pediatric rear-seat passengers, ages 7 to 14. Each was restrained by a three-point seatbelt and was driven for seventy-five minutes at night. Ten subjects used a high-back booster seat, ten used a low-back booster seat, and ten used none (based on the subject height and weight). The subjects were recorded with a low-light video camera, and one frame was analyzed per each minute of video. The high-back booster group exhibited a statistically significant (p<0.05) decrease in the mean frequency of poor shoulder belt fit compared to the no-booster and low-back booster groups. The high-back booster group also exhibited statistically significant decreases in the 90th percentile of the absolute value of the relative lateral motion of the head. The low-back booster group did not result in statistically significant decreases in poor shoulder belt fit or lateral head motion compared to the no-booster group. These results are consistent with the presence of large lateral supports of the high-back booster which provided support to the head while sleeping, reducing voluntary lateral occupant motion and improving shoulder belt fit. Future work includes examining lap belt fit in-transit, and examining the effects of these observations on predicted injury risk. PMID:22105378

Cost Effectiveness of a Shingles Vaccine Booster for Currently Vaccinated Adults in the U.S.

PubMed

Le, Phuc; Rothberg, Michael B

2017-12-01

The Advisory Committee on Immunization Practices recommends a single dose of the live attenuated herpes zoster vaccine in people aged ≥60 years. Because vaccine-induced protection decreases to zero after 10 years, many vaccinated people will soon be subject to an increased risk of the disease. The study objective was to determine the cost effectiveness of a herpes zoster vaccine booster and its optimal timing among immunocompetent adults first vaccinated at aged ≥60 years. A Markov model was built to follow vaccinated individuals for a lifetime. From the societal perspective, costs and quality-adjusted life years were compared between no booster versus booster options. A booster was given any time between 1 and 20 years after the first dose, and for those who had the first dose at different ages: 60, 70, and 80 years. Because people entered the model already vaccinated, costs and side effects of the first dose were not included. The booster was assumed to have the same efficacy and waning rate as the initial vaccination. Model inputs were based on published literature. A cost effectiveness threshold of $100,000/quality-adjusted life year was used. The analysis was conducted in 2016. Cost effectiveness of a booster varied by age and time since vaccination. The booster cost <$100,000/quality-adjusted life year if given >5 years after the initial dose, but was most cost effective at around 10 years. The finding was robust to wide variations in model inputs. Under current assumptions, a booster dose of herpes zoster vaccine would be cost effective for all vaccinated people 10 years after initial vaccination. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Response to booster doses of hepatitis B vaccine among young adults who had received neonatal vaccination.

PubMed

Chan, Paul K S; Ngai, Karry L K; Lao, Terence T; Wong, Martin C S; Cheung, Theresa; Yeung, Apple C M; Chan, Martin C W; Luk, Scotty W C

2014-01-01

Newborns who have received hepatitis B immunization in 1980s are now young adults joining healthcare disciplines. The need for booster, pre- and post-booster checks becomes a practical question. The aim of this study is to refine the HBV vaccination policy for newly admitted students in the future. A prospective study on medical and nursing school entrants to evaluate hepatitis B serostatus and the response to booster doses among young adults. Among 212 students, 17-23-year-old, born after adoption of neonatal immunization, 2 (0.9%) were HBsAg positive, 40 (18.9%) were anti-HBs positive. At 1 month after a single-dose booster for anti-HBs-negative students, 14.5% had anti-HBs <10 mIU/mL, 29.0% and 56.5% were 10-100 and >100 mIU/mL, respectively. The anti-HBs levels were significantly higher for females than males (mean [SD]: 431 [418] vs. 246 [339] mIU/mL, P = 0.047). At 2-4 month after the third booster dose, 97.1% had anti-HBs >100 mIU/mL and 2.9% had 10-100 mIU/mL. Pre-booster check is still worthwhile to identify carriers among newly recruited healthcare workers born after adoption of neonatal immunization. A 3-dose booster, rather than a single dose, is required for the majority to achieve an anti-HBs level >100 mIU/mL, as memory immunity has declined in a substantial proportion of individuals. Cost-effectiveness of post-booster check for anti-HBs is low and should be further evaluated based on contextual specific utilization of results.

NASA's B-52 mother ship carries the X-43A and its booster rocket on a captive carry flight Jan. 26, 2004

NASA Image and Video Library

2004-01-26

NASA's historic B-52 mother ship carried the X-43A and its Pegasus booster rocket on a captive carry flight from Edwards Air Force Base Jan. 26, 2004. The X-43A and its booster remained mated to the B-52 throughout the two-hour flight, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

Solid rocket motors for the Space Shuttle booster.

NASA Technical Reports Server (NTRS)

Odom, J. B.

1972-01-01

The evolution of the space shuttle booster system is reviewed from its initial concepts based on liquid-propellant reusable boosters to the final selection of recoverable, solid-fuel rocket motors. The rationale associated with each of the several major decisions in the evolution process is discussed. It is shown that the external tank orbiter configuration emerging from the latest studies takes maximum advantage of the solid rocket motor development experience and promises to be the optimum configuration for fulfilling the paramount shuttle program requirements of minimum total development risk within acceptable costs.

Predictors of Booster Response to Hepatitis B Vaccine at 15 years of age: A Cross-Sectional School-Based Study.

PubMed

Chen, Yu-Sheng; Chu, Chia-Hsiang; Wang, Jen-Hung; Lin, Jun-Song; Chang, Yung-Chieh

2016-08-01

The current consensus does not support the use of booster dose because of its anamnestic response in almost all children 15 years after universal infant hepatitis B virus (HBV) vaccination. However, in our clinical setting, numerous concerned parents request a booster administration for their children. We aimed to provide the possible predictors of booster response in adolescents before this booster administration. This study comprised a series of cross-sectional serological surveys of HBV markers in 15-year-old individuals between 2008 and 2012. Data on serum hepatitis B surface antigen, hepatitis B surface antibody (anti-HBs), and liver-function biomarkers in a total of 887 senior high-school students were collected. There were two parts to this study: HBV seroepidemiology and booster-response analysis to identify the possible response predictors and decay factors after the HBV booster administration. The overall anti-HBs and hepatitis B surface antigen seropositivity rates were 34.7% and 0.7%, respectively, and the median anti-HBs titer was 3.3 mIU/mL. Six weeks after one dose of recombinant HBV vaccine, the overall booster-response rate in the double-seronegative recipients was 94% (471/501). Among the participants whose initial anti-HBs titers were undetectable or low, 72.4% (247/341) and 95.6% (153/160), respectively, reactivated their anti-HBs titers ≥ 100 mIU/mL about 6 weeks after the booster administration. The likelihood of postbooster anti-HBs titer reaching an adequate protective level increased with the prebooster titer. The female participants had stronger anamnestic responses compared to the male participants. We found that the female participants and prebooster anti-HBs titers above the detection limit of the immunoassay were good predictors of HBV booster response. Copyright © 2015. Published by Elsevier B.V.

Space shuttle phase B wind tunnel model and test information. Volume 3: Launch configuration

NASA Technical Reports Server (NTRS)

Glynn, J. L.; Poucher, D. E.

1988-01-01

Archived wind tunnel data are available for flyback booster or other alternative recoverable configurations as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle. Considerable wind tunnel data was acquired by the competing contractors and the NASA Centers for an extensive variety of configurations with an array of wing and body planforms. All contractor and NASA wind tunnel data acquired in the Phase B development have been compiled into a data base and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration type. Basic components include booster, orbiter and launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbital configuration types include straight and delta wings, lifting body, drop tanks and double delta wings. This is Volume 3 (Part 2) of the report -- Launch Configuration -- which includes booster and orbiter components in various stacked and tandem combinations.

A Recipe for Soft Fluidic Elastomer Robots

PubMed Central

Marchese, Andrew D.; Katzschmann, Robert K.

2015-01-01

Abstract This work provides approaches to designing and fabricating soft fluidic elastomer robots. That is, three viable actuator morphologies composed entirely from soft silicone rubber are explored, and these morphologies are differentiated by their internal channel structure, namely, ribbed, cylindrical, and pleated. Additionally, three distinct casting-based fabrication processes are explored: lamination-based casting, retractable-pin-based casting, and lost-wax-based casting. Furthermore, two ways of fabricating a multiple DOF robot are explored: casting the complete robot as a whole and casting single degree of freedom (DOF) segments with subsequent concatenation. We experimentally validate each soft actuator morphology and fabrication process by creating multiple physical soft robot prototypes. PMID:27625913

A Recipe for Soft Fluidic Elastomer Robots.

PubMed

Marchese, Andrew D; Katzschmann, Robert K; Rus, Daniela

2015-03-01

This work provides approaches to designing and fabricating soft fluidic elastomer robots. That is, three viable actuator morphologies composed entirely from soft silicone rubber are explored, and these morphologies are differentiated by their internal channel structure, namely, ribbed, cylindrical, and pleated. Additionally, three distinct casting-based fabrication processes are explored: lamination-based casting, retractable-pin-based casting, and lost-wax-based casting. Furthermore, two ways of fabricating a multiple DOF robot are explored: casting the complete robot as a whole and casting single degree of freedom (DOF) segments with subsequent concatenation. We experimentally validate each soft actuator morphology and fabrication process by creating multiple physical soft robot prototypes.

Design optimization of gas generator hybrid propulsion boosters

NASA Technical Reports Server (NTRS)

Weldon, Vincent; Phillips, Dwight U.; Fink, Lawrence E.

1990-01-01

A methodology used in support of a contract study for NASA/MSFC to optimize the design of gas generator hybrid propulsion booster for uprating the National Space Transportation System (NSTS) is presented. The objective was to compare alternative configurations for this booster approach, optimizing each candidate concept on different bases, in order to develop data for a trade table on which a final decision was based. The methodology is capable of processing a large number of independent and dependent variables, adjusting the overall subsystems characteristics to arrive at a best compromise integrated design to meet various specified optimization criteria subject to selected constraints. For each system considered, a detailed weight statement was generated along with preliminary cost and reliability estimates.

Modelling the Cast Component Weight in Hot Chamber Die Casting using Combined Taguchi and Buckingham's π Approach

NASA Astrophysics Data System (ADS)

Singh, Rupinder

2018-02-01

Hot chamber (HC) die casting process is one of the most widely used commercial processes for the casting of low temperature metals and alloys. This process gives near-net shape product with high dimensional accuracy. However in actual field environment the best settings of input parameters is often conflicting as the shape and size of the casting changes and one have to trade off among various output parameters like hardness, dimensional accuracy, casting defects, microstructure etc. So for online inspection of the cast components properties (without affecting the production line) the weight measurement has been established as one of the cost effective method (as the difference in weight of sound and unsound casting reflects the possible casting defects) in field environment. In the present work at first stage the effect of three input process parameters (namely: pressure at 2nd phase in HC die casting; metal pouring temperature and die opening time) has been studied for optimizing the cast component weight `W' as output parameter in form of macro model based upon Taguchi L9 OA. After this Buckingham's π approach has been applied on Taguchi based macro model for the development of micro model. This study highlights the Taguchi-Buckingham based combined approach as a case study (for conversion of macro model into micro model) by identification of optimum levels of input parameters (based on Taguchi approach) and development of mathematical model (based on Buckingham's π approach). Finally developed mathematical model can be used for predicting W in HC die casting process with more flexibility. The results of study highlights second degree polynomial equation for predicting cast component weight in HC die casting and suggest that pressure at 2nd stage is one of the most contributing factors for controlling the casting defect/weight of casting.

A comparison of self-report and direct observation of booster seat use in Latino families.

PubMed

Quistberg, D Alex; Lozano, Paula; Mack, Christopher D; Schwartz, Rachel; Ebel, Beth E

2010-08-01

To develop a reliable self-report tool for measuring child booster seat use among Latino families. Cross-sectional and observational survey of a convenience sample. Five retail stores in King County, Washington. 50 parents of children 4-8 years old that self-identified as Latino or Hispanic. Parent-reported measures of how often the child uses a booster seat, if the child used a booster seat on the last trip, how often the child complains about using a booster seat, how often the child asks to not use a booster seat, and how often other families they know use a booster seat. Observed booster seat use by child. 26 children (52%) were observed using a booster seat. Parent-reported booster seat use was a poor predictor of observed booster seat use. Although 34 parents reported that their child 'always' uses a booster seat, 8 (24%) of these children were not using a booster seat. A logistic model to predict booster seat use had a sensitivity of 81% and a specificity of 71%, and misclassified 24% of the participants' observed use. Reliance on parent-reported booster seat use significantly overstated observed booster seat use in the study. Among this study population, accurate determination of booster seat use required direct observation.

A methodology for selective removal of orbital debris

NASA Technical Reports Server (NTRS)

Ash, R. L.; Odonoghue, P. J.; Chambers, E. J.; Raney, J. P.

1992-01-01

Earth-orbiting objects, large enough to be tracked, were surveyed for possible systematic debris removal. Based upon the statistical collision studies of others, it was determined that objects in orbits approximately 1000 km above the Earth's surface are at greatest collisional risk. Russian C-1B boosters were identified as the most important target of opportunity for debris removal. Currently, more than 100 in tact boosters are orbiting the Earth with apogees between 950 km and 1050 km. Using data provided by Energia USA, specific information on the C-1B booster, in terms of rendezvous and capture strategies, was discussed.

Performance evaluation of Space Shuttle SRB parachutes from air drop and scaled model wind tunnel tests. [Solid Rocket Booster recovery system

NASA Technical Reports Server (NTRS)

Moog, R. D.; Bacchus, D. L.; Utreja, L. R.

1979-01-01

The aerodynamic performance characteristics have been determined for the Space Shuttle Solid Rocket Booster drogue, main, and pilot parachutes. The performance evaluation on the 20-degree conical ribbon parachutes is based primarily on air drop tests of full scale prototype parachutes. In addition, parametric wind tunnel tests were performed and used in parachute configuration development and preliminary performance assessments. The wind tunnel test data are compared to the drop test results and both sets of data are used to determine the predicted performance of the Solid Rocket Booster flight parachutes. Data from other drop tests of large ribbon parachutes are also compared with the Solid Rocket Booster parachute performance characteristics. Parameters assessed include full open terminal drag coefficients, reefed drag area, opening characteristics, clustering effects, and forebody interference.

KSC-2011-1890

NASA Image and Video Library

2011-02-28

CAPE CANAVERAL, Fla. -- The Solid Rocket Booster Retrieval Ship Freedom Star leaves the dock at Hangar AF at Cape Canaveral Air Force Station and heads back to its home base at the Turn Basin at NASA's Kennedy Space Center in Florida. The ship recently retrieved a booster that was used during space shuttle Discovery's STS-133 launch from Kennedy's Launch Pad 39A on Feb. 24. The shuttle’s two solid rocket booster casings and associated flight hardware are recovered in the Atlantic Ocean after every launch by Liberty Star and Freedom Star. The boosters impact the Atlantic about seven minutes after liftoff and the retrieval ships are stationed about 10 miles from the impact area at the time of splashdown. After the spent segments are processed, they will be transported to Utah, where they will be refurbished and stored, if needed. Photo credit: NASA/Jim Grossmann

Influence of S. mutans on base-metal dental casting alloy toxicity.

PubMed

McGinley, E L; Dowling, A H; Moran, G P; Fleming, G J P

2013-01-01

We have highlighted that exposure of base-metal dental casting alloys to the acidogenic bacterium Streptococcus mutans significantly increases cellular toxicity following exposure to immortalized human TR146 oral keratinocytes. With Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), S. mutans-treated nickel-based (Ni-based) and cobalt-chromium-based (Co-Cr-based) dental casting alloys were shown to leach elevated levels of metal ions compared with untreated dental casting alloys. We targeted several biological parameters: cell morphology, viable cell counts, cell metabolic activity, cell toxicity, and inflammatory cytokine expression. S. mutans-treated dental casting alloys disrupted cell morphology, elicited significantly decreased viable cell counts (p < 0.0001) and cell metabolic activity (p < 0.0001), and significantly increased cell toxicity (p < 0.0001) and inflammatory cytokine expression (p < 0.0001). S. mutans-treated Ni-based dental casting alloys induced elevated levels of cellular toxicity compared with S. mutans-treated Co-Cr-based dental casting alloys. While our findings indicated that the exacerbated release of metal ions from S. mutans-treated base-metal dental casting alloys was the likely result of the pH reduction during S. mutans growth, the exact nature of mechanisms leading to accelerated dissolution of alloy-discs is not yet fully understood. Given the predominance of S. mutans oral carriage and the exacerbated cytotoxicity observed in TR146 cells following exposure to S. mutans-treated base-metal dental casting alloys, the implications for the long-term stability of base-metal dental restorations in the oral cavity are a cause for concern.

Output-Based Adaptive Meshing Applied to Space Launch System Booster Separation Analysis

NASA Technical Reports Server (NTRS)

Dalle, Derek J.; Rogers, Stuart E.

2015-01-01

This paper presents details of Computational Fluid Dynamic (CFD) simulations of the Space Launch System during solid-rocket booster separation using the Cart3D inviscid code with comparisons to Overflow viscous CFD results and a wind tunnel test performed at NASA Langley Research Center's Unitary PlanWind Tunnel. The Space Launch System (SLS) launch vehicle includes two solid-rocket boosters that burn out before the primary core stage and thus must be discarded during the ascent trajectory. The main challenges for creating an aerodynamic database for this separation event are the large number of basis variables (including orientation of the core, relative position and orientation of the boosters, and rocket thrust levels) and the complex flow caused by the booster separation motors. The solid-rocket boosters are modified from their form when used with the Space Shuttle Launch Vehicle, which has a rich flight history. However, the differences between the SLS core and the Space Shuttle External Tank result in the boosters separating with much narrower clearances, and so reducing aerodynamic uncertainty is necessary to clear the integrated system for flight. This paper discusses an approach that has been developed to analyze about 6000 wind tunnel simulations and 5000 flight vehicle simulations using Cart3D in adaptive-meshing mode. In addition, a discussion is presented of Overflow viscous CFD runs used for uncertainty quantification. Finally, the article presents lessons learned and improvements that will be implemented in future separation databases.

Lessons Learned for Follow-up Phone Booster Counseling Calls with Substance Abusing Emergency Department Patients

PubMed Central

Donovan, Dennis M.; Hatch-Maillette, Mary A.; Phares, Melissa M.; McGarry, Ernest; Peavy, K. Michelle; Taborsky, Julie

2014-01-01

Background Post-visit “booster” sessions have been recommended to augment the impact of brief interventions delivered in the Emergency Department (ED). This paper, which focuses on implementation issues, presents descriptive information and interventionists’ qualitative perspectives on providing brief interventions over the phone, challenges, “lessons learned”, and recommendations for others attempting to implement adjunctive booster calls. Method Attempts were made to complete two 20-minute telephone “booster” calls within a week following a patient’s ED discharge with 425 patients who screened positive for and had recent problematic substance use other than alcohol or nicotine. Results Over half (56.2%) of participants completed the initial call; 66.9% of those who received the initial call also completed the second call. Median number of attempts to successfully contact participants for the first and second calls was 4 and 3, respectively. Each completed call lasted an average of about 22 minutes. Common challenges/barriers identified by booster callers included unstable housing, limited phone access, unavailability due to additional treatment, lack of compensation for booster calls, and booster calls coming from an area code different than the participants’ locale and from someone other than ED staff. Conclusions Specific recommendations are presented with respect to implementing a successful centralized adjunctive booster call system. Future use of booster calls might be informed by research on contingency management (e.g., incentivizing call completions), smoking cessation quitlines, and phone-based continuing care for substance abuse patients. Future research needs to evaluate the incremental benefit of adjunctive booster calls on outcomes over and above that of brief motivational interventions delivered in the ED setting. PMID:25534151

Very High Cycle Fatigue Behavior of a Directionally Solidified Ni-Base Superalloy DZ4

PubMed Central

Nie, Baohua; Zhao, Zihua; Liu, Shu; Chen, Dongchu; Ouyang, Yongzhong; Hu, Zhudong; Fan, Touwen; Sun, Haibo

2018-01-01

The effect of casting pores on the very high cycle fatigue (VHCF) behavior of a directionally solidified (DS) Ni-base superalloy DZ4 is investigated. Casting and hot isostatic pressing (HIP) specimens were subjected to very high cycle fatigue loading in an ambient atmosphere. The results demonstrated that the continuously descending S-N curves were exhibited for both the casting and HIP specimens. Due to the elimination of the casting pores, the HIP samples had better fatigue properties than the casting samples. The subsurface crack initiated from the casting pore in the casting specimens at low stress amplitudes, whereas fatigue crack initiated from crystallographic facet decohesion for the HIP specimens. When considering the casting pores as initial cracks, there exists a critical stress intensity threshold ranged from 1.1 to 1.3 MPam, below which fatigue cracks may not initiate from the casting pores. Furthermore, the effect of the casting pores on the fatigue limit is estimated based on a modified El Haddad model, which is in good agreement with the experimental results. Fatigue life for both the casting and HIP specimens is well predicted using the Fatigue Indicator Parameter (FIP) model. PMID:29320429

Improved Safety and Cost Savings from Reductions in Cast-Saw Burns After Simulation-Based Education for Orthopaedic Surgery Residents.

PubMed

Bae, Donald S; Lynch, Hayley; Jamieson, Katherine; Yu-Moe, C Winnie; Roussin, Christopher

2017-09-06

The purpose of this investigation was to characterize the clinical efficacy and cost-effectiveness of simulation training aimed at reducing cast-saw injuries. Third-year orthopaedic residents underwent simulation-based instruction on distal radial fracture reduction, casting, and cast removal using an oscillating saw. The analysis compared incidences of cast-saw injuries and associated costs before and after the implementation of the simulation curriculum. Actual and potential costs associated with cast-saw injuries included wound care, extra clinical visits, and potential total payment (indemnity and expense payments). Curriculum costs were calculated through time-derived, activity-based accounting methods. The researchers compared the costs of cast-saw injuries and the simulation curriculum to determine overall savings and return on investment. In the 2.5 years prior to simulation, cast-saw injuries occurred in approximately 4.3 per 100 casts cut by orthopaedic residents. For the 2.5-year period post-simulation, the injury rate decreased significantly to approximately 0.7 per 100 casts cut (p = 0.002). The total cost to implement the casting simulation was $2,465.31 per 6-month resident rotation. On the basis of historical data related to cast-saw burns (n = 6), total payments ranged from $2,995 to $25,000 per claim. The anticipated savings from averted cast-saw injuries and associated medicolegal payments in the 2.5 years post-simulation was $27,131, representing an 11-to-1 return on investment. Simulation-based training for orthopaedic surgical residents was effective in reducing cast-saw injuries and had a high theoretical return on investment. These results support further investment in simulation-based training as cost-effective means of improving patient safety and clinical outcomes. Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

Quantitative Index and Abnormal Alarm Strategy Using Sensor-Dependent Vibration Data for Blade Crack Identification in Centrifugal Booster Fans

PubMed Central

Chen, Jinglong; Sun, Hailiang; Wang, Shuai; He, Zhengjia

2016-01-01

Centrifugal booster fans are important equipment used to recover blast furnace gas (BFG) for generating electricity, but blade crack faults (BCFs) in centrifugal booster fans can lead to unscheduled breakdowns and potentially serious accidents, so in this work quantitative fault identification and an abnormal alarm strategy based on acquired historical sensor-dependent vibration data is proposed for implementing condition-based maintenance for this type of equipment. Firstly, three group dependent sensors are installed to acquire running condition data. Then a discrete spectrum interpolation method and short time Fourier transform (STFT) are applied to preliminarily identify the running data in the sensor-dependent vibration data. As a result a quantitative identification and abnormal alarm strategy based on compound indexes including the largest Lyapunov exponent and relative energy ratio at the second harmonic frequency component is proposed. Then for validation the proposed blade crack quantitative identification and abnormality alarm strategy is applied to analyze acquired experimental data for centrifugal booster fans and it has successfully identified incipient blade crack faults. In addition, the related mathematical modelling work is also introduced to investigate the effects of mistuning and cracks on the vibration features of centrifugal impellers and to explore effective techniques for crack detection. PMID:27171083

Rough case-based reasoning system for continues casting

NASA Astrophysics Data System (ADS)

Su, Wenbin; Lei, Zhufeng

2018-04-01

The continuous casting occupies a pivotal position in the iron and steel industry. The rough set theory and the CBR (case based reasoning, CBR) were combined in the research and implementation for the quality assurance of continuous casting billet to improve the efficiency and accuracy in determining the processing parameters. According to the continuous casting case, the object-oriented method was applied to express the continuous casting cases. The weights of the attributes were calculated by the algorithm which was based on the rough set theory and the retrieval mechanism for the continuous casting cases was designed. Some cases were adopted to test the retrieval mechanism, by analyzing the results, the law of the influence of the retrieval attributes on determining the processing parameters was revealed. A comprehensive evaluation model was established by using the attribute recognition theory. According to the features of the defects, different methods were adopted to describe the quality condition of the continuous casting billet. By using the system, the knowledge was not only inherited but also applied to adjust the processing parameters through the case based reasoning method as to assure the quality of the continuous casting and improve the intelligent level of the continuous casting.

Space shuttle: Aerodynamic heating tests of the MDAC delta wing orbiter and canard booster

NASA Technical Reports Server (NTRS)

Andresen, T. L.

1972-01-01

Design of an efficient thermal protection system for the space shuttle orbiter and booster is discussed, based on knowledge of the thermal environment to be experienced by the vehicles in all flight phases. The complex configurations of these vehicles limit the level of confidence which can be associated with purely analytical thermal environment predictions. Tests were conducted during April and May 1971 using an orbiter and booster model at a 96-in. hypersonic shock tunnel. Both models were tested separately as well as together. A sufficiently large range in Reynolds number was covered so that laminar, transitional, and turbulent data could be obtained.

Remedial action suitability for the Cornhusker Army Ammunition Plant site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nonavinakere, S.; Rappa, P. III

1995-12-31

Numerous Department of Defense (DOD) sites across the nation are contaminated with explosive wastes due to munitions production during World War II, Korean Conflict and Vietnam Conflict. Production activities included explosives manufacturing, loading, packing, assembling, machining, casting and curing. Contaminants often present at these sites include TNT, RDX, HMX, Tetryl 2,4-DNT, 2,6-DNT, 1,3-DNB, 1,3,5-TNB and nitrobenzene. The Cornhusker Army Ammunition Plant (CAAP) is one such DOD site that has been determined to be contaminated with explosives. The CAAP is located approximately 2 miles west of the City of Grand Island in Hall County, Nebraska. The plant produced artillery, bombs, boosters,more » supplementary charges and various other experimental explosives. The purpose of this paper is to provide an overview of the site background, review of the remedial alternatives evaluation process and rationale behind the selection of present remedial action.« less

Year 5 Booster Units. The National Literacy Strategy.

ERIC Educational Resources Information Center

Department for Education and Employment, London (England).

The eight units of work in this document are designed to complement existing literacy booster units. Each unit is based on teaching objectives from the National Literacy Strategy Framework. They have been produced with the help of Year 5 teachers and have been trialled with pupils in a range of schools. The units support teachers' work with Year 5…

A Monte Carlo Analysis of the Thrust Imbalance for the RSRMV Booster During Both the Ignition Transient and Steady State Operation

NASA Technical Reports Server (NTRS)

Foster, Winfred A., Jr.; Crowder, Winston; Steadman, Todd E.

2014-01-01

This paper presents the results of statistical analyses performed to predict the thrust imbalance between two solid rocket motor boosters to be used on the Space Launch System (SLS) vehicle. Two legacy internal ballistics codes developed for the Space Shuttle program were coupled with a Monte Carlo analysis code to determine a thrust imbalance envelope for the SLS vehicle based on the performance of 1000 motor pairs. Thirty three variables which could impact the performance of the motors during the ignition transient and thirty eight variables which could impact the performance of the motors during steady state operation of the motor were identified and treated as statistical variables for the analyses. The effects of motor to motor variation as well as variations between motors of a single pair were included in the analyses. The statistical variations of the variables were defined based on data provided by NASA's Marshall Space Flight Center for the upgraded five segment booster and from the Space Shuttle booster when appropriate. The results obtained for the statistical envelope are compared with the design specification thrust imbalance limits for the SLS launch vehicle

A Monte Carlo Analysis of the Thrust Imbalance for the Space Launch System Booster During Both the Ignition Transient and Steady State Operation

NASA Technical Reports Server (NTRS)

Foster, Winfred A., Jr.; Crowder, Winston; Steadman, Todd E.

2014-01-01

This paper presents the results of statistical analyses performed to predict the thrust imbalance between two solid rocket motor boosters to be used on the Space Launch System (SLS) vehicle. Two legacy internal ballistics codes developed for the Space Shuttle program were coupled with a Monte Carlo analysis code to determine a thrust imbalance envelope for the SLS vehicle based on the performance of 1000 motor pairs. Thirty three variables which could impact the performance of the motors during the ignition transient and thirty eight variables which could impact the performance of the motors during steady state operation of the motor were identified and treated as statistical variables for the analyses. The effects of motor to motor variation as well as variations between motors of a single pair were included in the analyses. The statistical variations of the variables were defined based on data provided by NASA's Marshall Space Flight Center for the upgraded five segment booster and from the Space Shuttle booster when appropriate. The results obtained for the statistical envelope are compared with the design specification thrust imbalance limits for the SLS launch vehicle.

Three-dimensional microstructure simulation of Ni-based superalloy investment castings

NASA Astrophysics Data System (ADS)

Pan, Dong; Xu, Qingyan; Liu, Baicheng

2011-05-01

An integrated macro and micro multi-scale model for the three-dimensional microstructure simulation of Ni-based superalloy investment castings was developed, and applied to industrial castings to investigate grain evolution during solidification. A ray tracing method was used to deal with the complex heat radiation transfer. The microstructure evolution was simulated based on the Modified Cellular Automaton method, which was coupled with three-dimensional nested macro and micro grids. Experiments for Ni-based superalloy turbine wheel investment casting were carried out, which showed a good correspondence with the simulated results. It is indicated that the proposed model is able to predict the microstructure of the casting precisely, which provides a tool for the optimizing process.

Caste- and ethnicity-based inequalities in HIV/AIDS-related knowledge gap: a case of Nepal.

PubMed

Atteraya, Madhu; Kimm, HeeJin; Song, In Han

2015-05-01

Caste- and ethnicity-based inequalities are major obstacles to achieving health equity. The authors investigated whether there is any association between caste- and ethnicity-based inequalities and HIV-related knowledge within caste and ethnic populations. They used the 2011 Nepal Demographic and Health Survey, a nationally represented cross-sectional study data set. The study sample consisted of 11,273 women between 15 and 49 years of age. Univariate and logistic regression models were used to examine the relationship between caste- and ethnicity-based inequalities and HIV-related knowledge. The study sample was divided into high Hindu caste (47.9 percent), "untouchable" caste (18.4 percent), and indigenous populations (33.7 percent). Within the study sample, the high-caste population was found to have the greatest knowledge of the means by which HIV is prevented and transmitted. After controlling for socioeconomic and demographic characteristics, untouchables were the least knowledgeable. The odds ratio for incomplete knowledge about transmission among indigenous populations was 1.27 times higher than that for high Hindu castes, but there was no significant difference in knowledge of preventive measures. The findings suggest the existence of a prevailing HIV knowledge gap. This in turn suggests that appropriate steps need to be implemented to convey complete knowledge to underprivileged populations.

The effects of different types of investments on the alpha-case layer of titanium castings.

PubMed

Guilin, Yu; Nan, Li; Yousheng, Li; Yining, Wang

2007-03-01

Different types of investments affect the formation of the alpha-case (alpha-case) layer on titanium castings. This alpha-case layer may possibly alter the mechanical properties of cast titanium, which may influence the fabrication of removable and fixed prostheses. The formation mechanism for the alpha-case layer is not clear. The aim of this study was to evaluate the effect of 3 types of investments on the microstructure, composition, and microhardness of the alpha-case layer on titanium castings. Fifteen wax columns with a diameter of 5 mm and a length of 40 mm were divided into 3 groups of 5 patterns each. Patterns were invested using 3 types of investment materials, respectively, and were cast in pure titanium. The 3 types of materials tested were SiO(2)-, Al(2)O(3)-, and MgO-based investments. All specimens were sectioned and prepared for metallographic observation. The microstructure and composition of the surface reaction layer of titanium castings were investigated by scanning electron microscopy (SEM) and electron probe microanalysis (EPMA). The surface microhardness (VHN) for all specimens was measured using a hardness testing machine, and a mean value for each group was calculated. The alpha-case layer on titanium castings invested with SiO(2)-, Al(2)O(3)-, and MgO-based investments consisted of 3 layers-namely, the oxide layer, alloy layer, and hardening layer. In this study, the oxide layer and alloy layer were called the reaction layer. The thickness of the reaction layer for titanium castings using SiO(2)-, Al(2)O(3)-, and MgO-based investments was approximately 80 microm, 50 microm, and 14 microm, respectively. The surface microhardness of titanium castings made with SiO(2)-based investments was the highest, and that with MgO-based investments was the lowest. The type of investment affects the microstructure and microhardness of the alpha-case layer of titanium castings. Based on the thickness of the surface reaction layer and the surface microhardness of titanium castings, MgO-based investment materials may be the best choice for casting these materials.

Design study of the CEPC booster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Chuang

2014-12-10

Design study of the CEPC booster is reported. The booster provides 120 GeV beams for the collider with topup injection frequency of 0.1 Hz. To save cost, energy of the linac injector for the booster is chosen as 6GeV, corresponding to the magnetic field of 30 Gs. In this paper, lattice of the booster is described; the low injection energy issues are studied; beam transfer from linac to booster and from booster to collider are discussed.

Gendered-Caste Discrimination, Human Rights Education, and the Enforcement of the Prevention of Atrocities Act in India

ERIC Educational Resources Information Center

Kapoor, Dip

2007-01-01

Despite the constitutional ban on the practice of untouchability and caste-based discrimination, this article elaborates on a gendered-caste-based discriminatory reality in rural India, the difficulties of enforcing legal remedies, and on related human rights praxis to address gendered-caste atrocities by drawing on the experiences of a Canadian…

Cognitive behavioral therapy for adults with attention-deficit hyperactivity disorder: study protocol for a randomized controlled trial.

PubMed

Huang, Fang; Qian, Qiujin; Wang, Yufeng

2015-04-14

Attention-deficit hyperactivity disorder (ADHD) is a mental disorder beginning in childhood, and about half of patients have symptoms lasting into adulthood. Adult ADHD causes various impairments of emotional, self-esteem, and executive function and life quality aspects. Furthermore, adverse outcomes include academic and occupational failures, traffic accidents and substance abuse, which would be a family and social burden. A combination of medication and psychotherapy is recommended as the treatment for adult ADHD, and cognitive behavioral therapy (CBT) has been validated mostly with evidence-based researches. However, there has been a lack of randomized controlled trials of CBT for patients in China. Moreover, booster sessions of CBT for other disorders have proven effective in reducing recurrence and improving long-term outcomes, which has not been investigated for adult ADHD. This study will testify to the effect of CBT and explore the efficacy of subsequent booster sessions on adult ADHD. It is a three-armed randomized controlled trial to evaluate the efficacy of 12 weeks of CBT based on the published and validated manual and its booster sessions. The 12 weeks of CBT will be conducted weekly and will end at the 12th week, and then the booster sessions will be conducted monthly and end at the 24th week. There are three randomized groups, including a CBT with booster sessions group, a CBT group and a waiting group. Participants are outpatients of the Peking University Sixth Hospital who are diagnosed as having adult ADHD. The Primary efficacy endpoints are the scores of ADHD core symptoms at 12 and 24 weeks. Secondary endpoints include emotion, executive function, self-esteem, life quality and functional magnetic resonance imaging (fMRI) data at different time points, and the change within every group will also be analyzed. This is the first study to explore the efficacy of booster sessions of CBT in adult ADHD as far as we know. The results might increase proof of efficacy of CBT for adult ADHD in China, and the results showing efficacy of the booster sessions would also benefit our clinical practice. Current Controlled Trials: NCT02062411, date of registration: 12 February 2014.

[Exploring a new method for superimposition of pre-treatment and post-treatment mandibular digital dental casts in adults].

PubMed

Dai, F F; Liu, Y; Xu, T M; Chen, G

2018-04-18

To explore a cone beam computed tomography (CBCT)-independent method for mandibular digital dental cast superimposition to evaluate three-dimensional (3D) mandibular tooth movement after orthodontic treatment in adults, and to evaluate the accuracy of this method. Fifteen post-extraction orthodontic treatment adults from the Department of Orthodontics, Peking University School and Hospital of Stomatology were included. All the patients had four first premolars extracted, and were treated with straight wire appliance. The pre- and post-treatment plaster dental casts and craniofacial CBCT scans were obtained. The plaster dental casts were transferred to digital dental casts by 3D laser scanning, and lateral cephalograms were created from the craniofacial CBCT scans by orthogonal projection. The lateral cephalogram-based mandibular digital dental cast superimposition was achieved by sequential maxillary dental cast superimposition registered on the palatal stable region, occlusal transfer, and adjustment of mandibular rotation and translation obtained from lateral cephalogram superimposition. The accuracy of the lateral cephalogram-based mandibular digital dental cast superimposition method was evaluated with the CBCT-based mandibular digital dental cast superimposition method as the standard reference. After mandibular digital dental cast superimposition using both methods, 3D coordinate system was established, and 3D displacements of the lower bilateral first molars, canines and central incisors were measured. Differences between the two superimposition methods in tooth displacement measurements were assessed using the paired t-test with the level of statistical significance set at P<0.05. No significant differences were found between the lateral cephalogram-based and CBCT-based mandibular digital dental cast superimposition methods in 3D displacements of the lower first molars, and sagittal and vertical displacements of the canines and central incisors; transverse displacements of the canines and central incisors differed by (0.3±0.5) mm with statistical significance. The lateral cephalogram-based mandibular digital dental cast superimposition method has the similar accuracy as the CBCT-based mandibular digital dental cast superimposition method in 3D evaluation of mandibular orthodontic tooth displacement, except for minor differences for the transverse displacements of anterior teeth. This method is applicable to adult patients with conventional orthodontic treatment records, especially the previous precious orthodontic data in the absence of CBCT scans.

Hepatitis B virus vaccination booster does not provide additional protection in adolescents: a cross-sectional school-based study.

PubMed

Chang, Yung-Chieh; Wang, Jen-Hung; Chen, Yu-Sheng; Lin, Jun-Song; Cheng, Ching-Feng; Chu, Chia-Hsiang

2014-09-23

Current consensus does not support the use of a universal booster of hepatitis B virus (HBV) vaccine because there is an anamnestic response in almost all children 15 years after universal infant HBV vaccination. We aimed to provide a booster strategy among adolescents as a result of their changes in lifestyle and sexual activity. This study comprised a series of cross-sectional serological surveys of HBV markers in four age groups between 2004 and 2012. The seropositivity rates of hepatitis B surface antigen (HBsAg) and its reciprocal antibody (anti-HBs) for each age group were collected. There were two parts to this study; age-specific HBV seroepidemiology and subgroup analysis, including effects of different vaccine types, booster response for immunogenicity at 15 years of age, and longitudinal follow-up to identify possible additional protection by HBV booster. Within the study period, data on serum anti-HBs and HBsAg in a total of 6950 students from four age groups were collected. The overall anti-HBs and HBsAg seropositivity rates were 44.3% and 1.2%, respectively. The anti-HBs seropositivity rate in the plasma-derived subgroup was significantly higher in both 15- and 18-year age groups. Overall response rate in the double-seronegative recipients at 15 years of age was 92.5% at 6 weeks following one recombinant HBV booster dose. Among the 24 recipients showing anti-HBs seroconversion at 6 weeks after booster, seven subjects (29.2%) had lost their anti-HBs seropositivity again within 3 years. Increased seropositivity rates and titers of anti-HBs did not provide additional protective effects among subjects comprehensively vaccinated against HBV in infancy. HBV booster strategy at 15 years of age was the main contributor to the unique age-related phenomenon of anti-HBs seropositivity rate and titer. No increase in HBsAg seropositivity rates within different age groups was observed. Vaccination with plasma-derived HBV vaccines in infancy provided higher anti-HBs seropositivity at 15-18 years of age. Overall booster response rate was 92.5% and indicated that intact immunogenicity persisted at least 15 years after primary HBV vaccination in infancy. Booster vaccination of HBV did not confer additional protection against HBsAg carriage in our study.

Developing the World's Most Powerful Solid Booster

NASA Technical Reports Server (NTRS)

Priskos, Alex S.; Frame, Kyle L.

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are underway with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant grain, asbestos-free case insulation, a redesigned nozzle, streamlined manufacturing processes, and new inspection techniques. New materials and processes provide improved performance, safety, and affordability but also have led to challenges for the government/industry development team. The team completed its first full-size qualification motor test firing in early 2015. The second is scheduled for mid-2016. This paper will discuss booster accomplishments to date, as well as challenges and milestones ahead.

Booster vaccination of pre-school children with reduced-antigen-content diphtheria-tetanus-acellular pertussis-inactivated poliovirus vaccine co-administered with measles-mumps-rubella-varicella vaccine

PubMed Central

Ferrera, Giuseppe; Cuccia, Mario; Mereu, Gabriele; Icardi, Giancarlo; Bona, Gianni; Esposito, Susanna; Marchetti, Federico; Messier, Marc; Kuriyakose, Sherine; Hardt, Karin

2012-01-01

Background: Pertussis occurs in older children, adolescents and adults due to waning immunity after primary vaccination. Booster vaccination for pre-school children has been recommended in Italy since 1999. In this study (NCT00871000), the immunogenicity, safety and reactogenicity of a booster dose of reduced-antigen content diphtheria-tetanus-acellular pertussis-inactivated poliovirus vaccine (dTpa-IPV; GSK Biologicals Boostrix™-Polio; 3-component pertussis) vs. full-strength DTPa-IPV vaccine (sanofi-pasteur—MSD Tetravac™; 2-component pertussis) was evaluated in pre-school Italian children.   Methods: Healthy children aged 5–6 y primed in a routine vaccination setting with three doses of DTPa-based vaccines were enrolled and randomized (1:1) in this phase IIIb, booster study to receive a single dose of dTpa-IPV or DTPa-IPV; the MMRV vaccine was co-administered. Antibody concentrations/titers against diphtheria, tetanus, pertussis and poliovirus 1–3 were measured before and one month post-booster. Reactogenicity and safety was assessed. Results: 305 subjects were enrolled of whom 303 (dTpa-IPV = 151; DTPa-IPV = 152) received booster vaccination. One month post-booster, all subjects were seroprotected/seropositive for anti-diphtheria, anti-tetanus, anti-PT, anti-FHA and anti-poliovirus 1–3; 99.3% of dTpa-IPV and 60.4% of DTPa-IPV subjects were seropositive for anti-PRN; 98–100% of subjects were seropositive against MMRV antigens post-booster. Pain at the injection site (dTpa-IPV: 63.6%; DTPa-IPV: 63.2%) and fatigue (dTpa-IPV: 26.5%; DTPa-IPV: 23.7%) were the most commonly reported solicited local and general symptoms, during the 4-d follow-up period. No SAEs or fatalities were reported. Conclusions: The reduced-antigen-content dTpa-IPV vaccine was non-inferior to full-strength DTPa-IPV vaccine with respect to immunogenicity. The vaccine was well-tolerated and can be confidently used as a booster dose in pre-school children. PMID:22327497

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

NASA Technical Reports Server (NTRS)

Crocker, Andy; Greene, William D.

2017-01-01

Goals of NASA's Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to: (1) Reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS. (2) Enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. SLS Block 1 vehicle is being designed to carry 70 mT to LEO: (1) Uses two five-segment solid rocket boosters (SRBs) similar to the boosters that helped power the space shuttle to orbit. Evolved 130 mT payload class rocket requires an advanced booster with more thrust than any existing U.S. liquid-or solid-fueled boosters

An Experimental study of Corner Turning in a Granular Ammonium Nitrate Based Explosive

NASA Astrophysics Data System (ADS)

Sorber, Susan; Taylor, Peter

2007-06-01

A novel experimental geometry has been designed to perform controlled studies of corner turning in a ``tap density'' granular explosive. It enables the study of corner turning and detonation properties with high speed framing camera, piezo probes and ionization probes. The basic geometry consists of a large diameter PMMA cylinder filled with the granular explosive which is initiated on axis from below by a smaller diameter cylinder of the same explosive or a booster charge. Four experiments have been performed on a granular Ammonium Nitrate based non ideal explosive (NIE). Two experiments were initiated directly from a PE4 booster charge and two were initiated from a train including a booster charge and a 1'' diameter Copper cylinder containing the same NIE. Data from the four experiments was reproducible and observed detonation and shock waves showed good 2-D symmetry. Detonation phase velocity on the vertical side of the main container was observed and both shock and detonation velocities were observed in the corner turning region along the base of the main container. Analysis of the data shows that the booster initiated geometries with a higher input shock pressure into the NIE gave earlier detonation arrival at the lowest probes on the container side. The corner turning data is compared to a hydrocode calculation using a simple JWL++ reactive burn model.

An Experimental Study of Corner Turning in a Granular Ammonium Nitrate Based Explosive

NASA Astrophysics Data System (ADS)

Sorber, S.; Taylor, P.; Burns, M.

2007-12-01

A novel experimental geometry has been designed to perform controlled studies of corner turning in a "tap density" granular explosive. It enables the study of corner turning and detonation properties with high speed framing camera, piezo probes and ionisation probes. The basic geometry consists of a large diameter PMMA cylinder filled with the granular explosive and is initiated on axis from below by a smaller diameter cylinder of granular explosive or a booster charge. Four experiments were performed on a granular Ammonium Nitrate based non-ideal explosive (NIE). Two experiments were initiated directly with the PE4 booster and two were initiated from a train including a booster charge and a 1″ diameter copper cylinder containing the same NIE. Experimental data from the four experiments was reproducible and the observed detonation and shock waves showed good 2-D symmetry. Detonation phase velocity on the vertical side of the main container was observed and both shock and detonation velocities were observed in the corner turning region along the base of the main container. Analysis of the data shows that the booster-initiated geometries with a higher input shock pressure into the granular explosive gave earlier detonation arrival at the lowest probes on the container side. The corner turning data is compared to a hydrocode calculation using a simple JWL++ reactive burn model.

47 CFR 27.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 27.9... boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies... operate a signal booster. [78 FR 21564, Apr. 11, 2013] ...

47 CFR 27.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 27.9... boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies... operate a signal booster. [78 FR 21564, Apr. 11, 2013] ...

Generation and evaluation of 3D digital casts of maxillary defects based on multisource data registration: A pilot clinical study.

PubMed

Ye, Hongqiang; Ma, Qijun; Hou, Yuezhong; Li, Man; Zhou, Yongsheng

2017-12-01

Digital techniques are not clinically applied for 1-piece maxillary prostheses containing an obturator and removable partial denture retained by the remaining teeth because of the difficulty in obtaining sufficiently accurate 3-dimensional (3D) images. The purpose of this pilot clinical study was to generate 3D digital casts of maxillary defects, including the defective region and the maxillary dentition, based on multisource data registration and to evaluate their effectiveness. Twelve participants with maxillary defects were selected. The maxillofacial region was scanned with spiral computer tomography (CT), and the maxillary arch and palate were scanned using an intraoral optical scanner. The 3D images from the CT and intraoral scanner were registered and merged to form a 3D digital cast of the maxillary defect containing the anatomic structures needed for the maxillary prosthesis. This included the defect cavity, maxillary dentition, and palate. Traditional silicone impressions were also made, and stone casts were poured. The accuracy of the digital cast in comparison with that of the stone cast was evaluated by measuring the distance between 4 anatomic landmarks. Differences and consistencies were assessed using paired Student t tests and the intraclass correlation coefficient (ICC). In 3 participants, physical resin casts were produced by rapid prototyping from digital casts. Based on the resin casts, maxillary prostheses were fabricated by using conventional methods and then evaluated in the participants to assess the clinical applicability of the digital casts. Digital casts of the maxillary defects were generated and contained all the anatomic details needed for the maxillary prosthesis. Comparing the digital and stone casts, a paired Student t test indicated that differences in the linear distances between landmarks were not statistically significant (P>.05). High ICC values (0.977 to 0.998) for the interlandmark distances further indicated the high degree of consistency between the digital and stone casts. The maxillary prostheses showed good clinical effectiveness, indicating that the corresponding digital casts met the requirements for clinical application. Based on multisource data from spiral CT and the intraoral scanner, 3D digital casts of maxillary defects were generated using the registration technique. These casts were consistent with conventional stone casts in terms of accuracy and were suitable for clinical use. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

The one year effects of three doses of hepatitis B vaccine as a booster in anti-HBs-negative children 11-15 years after primary immunization; China, 2009-2011.

PubMed

Yao, Jun; Shan, Huan; Chen, Yongdi; Jiang, Zheng-gang; Dai, Xue-wei; Ren, Jing-jing; Xu, Kai-jin; Ruan, Bing; Yang, Shi-gui; Li, Qian

2015-01-01

The aim of this study was to evaluate hepatitis B surface antibody (anti-HBs) levels one year after hepatitis B booster vaccination in anti-HBs-negative (<10 mIU/mL) children 11-15 y after primary vaccination. Anti-HBs titers were examined in 235 children who were negative for hepatitis B surface antigen (HBsAg), anti-HBs, and hepatitis B core antibody (anti-HBc). The children were then divided into 3 groups based on their anti-HBs levels pre-booster: Group I, <0 .1 mIU/mL; Group II, 0.1 to <1 .0 mIU/mL; and Group III, 1.0 to <10 .0 mIU/mL. They were vaccinated with 3 doses of hepatitis B vaccine (0-1-6 month, 20 ug), and anti-HBs levels were measured. One month after the first dose, the anti-HBs positive rates (≥ 10 mIU/mL) in Groups I-III were 56.14%, 83.61% and 100%. One month after the third dose, the anti-HBs-positive rates in Groups I-III were 96.49%, 98.36% and 100%. One year after the third dose, the anti-HBs-positive rates in Groups I-III were 73.68%, 75.41% and 98.29%, respectively. Protective levels declined more rapidly for those with lower titers. Children with pre-booster anti-HBs titers of 1-9.9 mIU/mL might not need any booster dose, and the children with pre-booster titers of 0.1-0.9 and <0 .1 mIU/mL might need more than one dose booster vaccination.

The one year effects of three doses of hepatitis B vaccine as a booster in anti-HBs-negative children 11–15 years after primary immunization; China, 2009–2011

PubMed Central

Yao, Jun; Shan, Huan; Chen, Yongdi; Jiang, Zheng-gang; Dai, Xue-wei; Ren, Jing-jing; Xu, Kai-jin; Ruan, Bing; Yang, Shi-gui; Li, Qian

2015-01-01

The aim of this study was to evaluate hepatitis B surface antibody (anti-HBs) levels one year after hepatitis B booster vaccination in anti-HBs-negative (<10 mIU/mL) children 11–15 y after primary vaccination. Anti-HBs titers were examined in 235 children who were negative for hepatitis B surface antigen (HBsAg), anti-HBs, and hepatitis B core antibody (anti-HBc). The children were then divided into 3 groups based on their anti-HBs levels pre-booster: Group I, <0 .1 mIU/mL; Group II, 0.1 to <1 .0 mIU/mL; and Group III, 1.0 to <10 .0 mIU/mL. They were vaccinated with 3 doses of hepatitis B vaccine (0–1–6 month, 20 ug), and anti-HBs levels were measured. One month after the first dose, the anti-HBs positive rates (≥10 mIU/mL) in Groups I–III were 56.14%, 83.61% and 100%. One month after the third dose, the anti-HBs-positive rates in Groups I–III were 96.49%, 98.36% and 100%. One year after the third dose, the anti-HBs-positive rates in Groups I–III were 73.68%, 75.41% and 98.29%, respectively. Protective levels declined more rapidly for those with lower titers. Children with pre-booster anti-HBs titers of 1–9.9 mIU/mL might not need any booster dose, and the children with pre-booster titers of 0.1–0.9 and <0 .1 mIU/mL might need more than one dose booster vaccination. PMID:25692413

Feasibility demonstration of booster cross-over system for 3 1/2 inch SRB/MLP frangible nut system

NASA Technical Reports Server (NTRS)

1983-01-01

Recent testing of the SRB/MLP Frangible Nut System (SOS Part Number 114850-9/Boosters P/N 114848-3) at NASA indicated a need to reduce the function time between boosters (2) within a single frangible nut. These boosters are initiated separately by electrical impulse(s). Coupling the output of each detonator with an explosive cross-over would reduce the function time between boosters (independent of electrical impulse) while providing additional redundancy to the system. The objectives of this program were to: provide an explosive cross-over between boosters, reduce function time between boosters to less than one (1) millisecond within a given nut, reduce cost of boosters, be compatible with the existing frangible nut system, and meet requirements of USBI Spec's (nut 10SPC-0030, booster 10SPC-0031).

KSC-2009-1386

NASA Image and Video Library

2008-12-04

VANDENBERG AIR FORCE BASE, Calif. – Another solid rocket booster arrives on Space Launch Complex 2 at Vandenberg Air Force Base in California. The booster will be lifted into the service tower and installed on the Delta II rocket for the NOAA-N Prime satellite. NOAA-N Prime is the latest polar-orbiting operational environmental weather satellite developed by NASA for the National Oceanic and Atmospheric Administration. It is built by Lockheed Martin and similar to NOAA-N launched on May 20, 2005. Launch of NOAA-N Prime is scheduled for Feb. 4. Photo credit: NASA/Joe Davila, VAFB

KSC-2009-1383

NASA Image and Video Library

2008-12-04

VANDENBERG AIR FORCE BASE, Calif. – A solid rocket booster arrives on Space Launch Complex 2 at Vandenberg Air Force Base in California. The booster will be lifted into the service tower and installed on the Delta II rocket for the NOAA-N Prime satellite. NOAA-N Prime is the latest polar-orbiting operational environmental weather satellite developed by NASA for the National Oceanic and Atmospheric Administration. It is built by Lockheed Martin and similar to NOAA-N launched on May 20, 2005. Launch of NOAA-N Prime is scheduled for Feb. 4. Photo credit: NASA/Joe Davila, VAFB

KSC-2009-1385

NASA Image and Video Library

2008-12-04

VANDENBERG AIR FORCE BASE, Calif. – On Space Launch Complex 2 at Vandenberg Air Force Base in California, a solid rocket booster is lifted alongside the Delta II rocket for installation. The booster is being prepared for the launch of the NOAA-N Prime satellite. NOAA-N Prime is the latest polar-orbiting operational environmental weather satellite developed by NASA for the National Oceanic and Atmospheric Administration. It is built by Lockheed Martin and similar to NOAA-N launched on May 20, 2005. Launch of NOAA-N Prime is scheduled for Feb. 4. Photo credit: NASA/Joe Davila, VAFB

Obtaining of High Cr Content Cast Iron Materials

NASA Astrophysics Data System (ADS)

Florea, C.; Bejinariu, C.; Carcea, I.; Cimpoesu, N.; Chicet, D. L.; Savin, C.

2017-06-01

We have obtained, through the classic casting process, 3 highly chromium-based experimental alloys proposed for replacing the FC 250 classical cast iron in braking applications. Casting was carried out in an induction furnace and cast into moulds made of KALHARTZ 8500 resin casting mixture and HARTER hardener at SC RanCon SRL Iasi. It is known that the microstructure of the cast iron is a combination of martensite with a small amount of residual austenite after the heat treatment of the ingot. In the case of high-alloy chromium alloys, the performance of the material is due to the presence of M7C3 carbides distributed in the iron matrix Resistance to machining and deformation is based on alloy composition and microstructure, while abrasion resistance will depend on properties and wear conditions.

Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Oral Presentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Araya, Million

2015-08-25

SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hzmore » 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervalswhere the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.« less

Design and Evaluation of a Clock Multiplexing Circuit for the SSRL Booster Accelerator Timing System - Final Paper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Araya, Million

2015-08-21

SPEAR3 is a 234 m circular storage ring at SLAC’s synchrotron radiation facility (SSRL) in which a 3 GeV electron beam is stored for user access. Typically the electron beam decays with a time constant of approximately 10hr due to electron lose. In order to replenish the lost electrons, a booster synchrotron is used to accelerate fresh electrons up to 3GeV for injection into SPEAR3. In order to maintain a constant electron beam current of 500mA, the injection process occurs at 5 minute intervals. At these times the booster synchrotron accelerates electrons for injection at a 10Hz rate. A 10Hzmore » 'injection ready' clock pulse train is generated when the booster synchrotron is operating. Between injection intervals-where the booster is not running and hence the 10 Hz ‘injection ready’ signal is not present-a 10Hz clock is derived from the power line supplied by Pacific Gas and Electric (PG&E) to keep track of the injection timing. For this project I constructed a multiplexing circuit to 'switch' between the booster synchrotron 'injection ready' clock signal and PG&E based clock signal. The circuit uses digital IC components and is capable of making glitch-free transitions between the two clocks. This report details construction of a prototype multiplexing circuit including test results and suggests improvement opportunities for the final design.« less

Efficacy and Duration of Immunity after Yellow Fever Vaccination: Systematic Review on the Need for a Booster Every 10 Years

PubMed Central

Gotuzzo, Eduardo; Yactayo, Sergio; Córdova, Erika

2013-01-01

Current regulations stipulate a yellow fever (YF) booster every 10 years. We conducted a systematic review of the protective efficacy and duration of immunity of YF vaccine in residents of disease-endemic areas and in travelers to assess the need for a booster in these two settings and in selected populations (human immunodeficiency virus–infected persons, infants, children, pregnant women, and severely malnourished persons). Thirty-six studies and 22 reports were included. We identified 12 studies of immunogenicity, 8 of duration of immunity, 8 of vaccine response in infants and children, 7 of human-immunodeficiency virus–infected persons, 2 of pregnant women, and 1 of severely malnourished children. Based on currently available data, a single dose of YF vaccine is highly immunogenic and confers sustained life-long protective immunity against YF. Therefore, a booster dose of YF vaccine is not needed. Special considerations for selected populations are detailed. PMID:24006295

KSC-08pd1859

NASA Image and Video Library

2008-07-01

CAPE CANAVERAL, Fla. – In the Assembly and Refurbishment Facility at NASA's Kennedy Space Center, a crane is lowered over the aft skirt for the Ares 1-X rocket. The segment is being lifted into a machine shop work stand for drilling modifications. The modifications will prepare it for the installation of the auxiliary power unit controller, the reduced-rate gyro unit, the booster decelerator motors and the booster tumble motors. Ares I is an in-line, two-stage rocket that will transport the Orion crew exploration vehicle to low-Earth orbit. Ares I-X is a test rocket. The Ares I first stage will be a five-segment solid rocket booster based on the four-segment design used for the shuttle. Ares I’s fifth booster segment allows the launch vehicle to lift more weight and reach a higher altitude before the first stage separates from the upper stage, which ignites in midflight to propel the Orion spacecraft to Earth orbit. Photo credit: NASA/Jim Grossmann

BERLinPro Booster Cavity Design, Fabrication and Test Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burrill, Andrew; Anders, W; Frahm, A.

2014-12-01

The bERLinPro project, a 100 mA, 50 MeV superconducting RF (SRF) Energy Recovery Linac (ERL) is under construction at Helmholtz-Zentrum Berlin for the purpose of studying the technical challenges and physics of operating a high current, c.w., 1.3 GHz ERL. This machine will utilize three unique SRF cryomodules for the injector, booster and linac module respectively. The booster cryomodule will contain three 2-cell SRF cavities, based on the original design by Cornell University, and will be equipped with twin 115 kW RF power couplers in order to provide the appropriate acceleration to the high current electron beam. This paper willmore » review the status of the fabrication of the 4 booster cavities that have been built for this project by Jefferson Laboratory and look at the challenges presented by the incorporation of fundamental power couplers capable of delivering 115 kW. The test plan for the cavities and couplers will be given along with a brief overview of the cryomodule design.« less

47 CFR 74.1203 - Interference.

Code of Federal Regulations, 2014 CFR

2014-10-01

... FM Broadcast Booster Stations § 74.1203 Interference. (a) An authorized FM translator or booster..., TV booster, FM translator or FM booster station; or (3) The direct reception by the public of the off... FM booster stations. Interference will be considered to occur whenever reception of a regularly used...

47 CFR 74.1203 - Interference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... FM Broadcast Booster Stations § 74.1203 Interference. (a) An authorized FM translator or booster..., TV booster, FM translator or FM booster station; or (3) The direct reception by the public of the off... FM booster stations. Interference will be considered to occur whenever reception of a regularly used...

47 CFR 74.1203 - Interference.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FM Broadcast Booster Stations § 74.1203 Interference. (a) An authorized FM translator or booster..., TV booster, FM translator or FM booster station; or (3) The direct reception by the public of the off... FM booster stations. Interference will be considered to occur whenever reception of a regularly used...

47 CFR 74.1203 - Interference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... FM Broadcast Booster Stations § 74.1203 Interference. (a) An authorized FM translator or booster..., TV booster, FM translator or FM booster station; or (3) The direct reception by the public of the off... FM booster stations. Interference will be considered to occur whenever reception of a regularly used...

47 CFR 74.1233 - Processing FM translator and booster station applications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 4 2014-10-01 2014-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

47 CFR 74.1233 - Processing FM translator and booster station applications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 4 2012-10-01 2012-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

47 CFR 74.733 - UHF translator signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 4 2014-10-01 2014-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

47 CFR 74.1233 - Processing FM translator and booster station applications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 4 2011-10-01 2011-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

47 CFR 74.733 - UHF translator signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 4 2013-10-01 2013-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

47 CFR 74.1233 - Processing FM translator and booster station applications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 4 2013-10-01 2013-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

47 CFR 74.1233 - Processing FM translator and booster station applications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Processing FM translator and booster station... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1233 Processing FM translator and booster station applications. (a) Applications for FM translator and booster stations are...

47 CFR 74.733 - UHF translator signal boosters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false UHF translator signal boosters. 74.733 Section... Translator, and TV Booster Stations § 74.733 UHF translator signal boosters. (a) The licensee of a UHF television broadcast translator station may be authorized to operate one or more signal boosters for the...

Space shuttle with common fuel tank for liquid rocket booster and main engines (supertanker space shuttle)

NASA Technical Reports Server (NTRS)

Thorpe, Douglas G.

1991-01-01

An operation and schedule enhancement is shown that replaces the four-body cluster (Space Shuttle Orbiter (SSO), external tank, and two solid rocket boosters) with a simpler two-body cluster (SSO and liquid rocket booster/external tank). At staging velocity, the booster unit (liquid-fueled booster engines and vehicle support structure) is jettisoned while the remaining SSO and supertank continues on to orbit. The simpler two-bodied cluster reduces the processing and stack time until SSO mate from 57 days (for the solid rocket booster) to 20 days (for the liquid rocket booster). The areas in which liquid booster systems are superior to solid rocket boosters are discussed. Alternative and future generation vehicles are reviewed to reveal greater performance and operations enhancements with more modifications to the current methods of propulsion design philosophy, e.g., combined cycle engines, and concentric propellant tanks.

Initiation Capacity of a Specially Shaped Booster Pellet and Numerical Simulation of Its Initiation Process

NASA Astrophysics Data System (ADS)

Hu, Li-Shuang; Hu, Shuang-Qi; Cao, Xiong; Zhang, Jian-Ren

2014-01-01

The insensitive main charge explosive is creating new requirements for the booster pellet of detonation trains. The traditional cylindrical booster pellet has insufficient energy output to reliably initiate the insensitive main charge explosive. In this research, a concave spherical booster pellet was designed. The initiation capacity of the concave spherical booster pellet was studied using varied composition and axial steel dent methods. The initiation process of the concave spherical booster pellet was also simulated by ANSYS/LS-DYNA. The results showed that using a concave spherical booster allows a 42% reduction in the amount of explosive needed to match the initiation capacity of a conventional cylindrical booster of the same dimensions. With the other parameters kept constant, the initiation capacity of the concave spherical booster pellet increases with decreased cone angle and concave radius. The numerical simulation results are in good agreement with the experimental data.

Tailored interventions for screening mammography among a sample of initially non-adherent women: when is a booster dose important?

PubMed

Skinner, Celette Sugg; Kobrin, Sarah C; Monahan, Patrick O; Daggy, Joanne; Menon, Usha; Todora, Helen Smith; Champion, Victoria L

2007-01-01

To assess added value of a booster dose of a tailored mammography intervention. Participants, non-adherent at baseline, were randomly assigned to usual care or one of three tailored interventions. Intervention group members (n=657) were further randomly assigned to receive/not receive a booster intervention dose. Electronic record mammography data were collected following initial intervention and at 6 and 15 months post-booster. Booster had no effect among women not screened after first intervention dose (n=337). Among women screened after initial dose (n=320), booster predicted re-screening at 6 but not 15 months. A boosterxrace interaction showed a booster effect at 6 months for African Americans (OR=4.66, p=.0005) but not Caucasians (OR=0.74, p=.44). Findings suggest if a first-dose intervention does not facilitate screening, neither will a booster dose. However, among women for whom a first dose is effective, boosters can facilitate timely repeat adherence, especially among African Americans. At 6 months booster recipients were less likely to be off-schedule but, by 15 months, the groups were similar. Boosters may effect when, but not whether, women continue screening.

Modular Approach to Launch Vehicle Design Based on a Common Core Element

NASA Technical Reports Server (NTRS)

Creech, Dennis M.; Threet, Grady E., Jr.; Philips, Alan D.; Waters, Eric D.; Baysinger, Mike

2010-01-01

With a heavy lift launch vehicle as the centerpiece of our nation's next exploration architecture's infrastructure, the Advanced Concepts Office at NASA's Marshall Space Flight Center initiated a study to examine the utilization of elements derived from a heavy lift launch vehicle for other potential launch vehicle applications. The premise of this study is to take a vehicle concept, which has been optimized for Lunar Exploration, and utilize the core stage with other existing or near existing stages and boosters to determine lift capabilities for alternative missions. This approach not only yields a vehicle matrix with a wide array of capabilities, but also produces an evolutionary pathway to a vehicle family based on a minimum development and production cost approach to a launch vehicle system architecture, instead of a purely performance driven approach. The upper stages and solid rocket booster selected for this study were chosen to reflect a cross-section of: modified existing assets in the form of a modified Delta IV upper stage and Castor-type boosters; potential near term launch vehicle component designs including an Ares I upper stage and 5-segment boosters; and longer lead vehicle components such as a Shuttle External Tank diameter upper stage. The results of this approach to a modular launch system are given in this paper.

Space shuttle phase B. Volume 2: Technical summary, addendum A

NASA Technical Reports Server (NTRS)

1971-01-01

A study was conducted to analyze the characteristics and performance data for the booster vehicles to be used with the space shuttle operations. It was determined that the single pressure-fed booster offered the lowest program cost per flight of the pressure-fed booster arrangements studied. The fly back booster required the highest peak annual funding and highest program cost. It was recommended that the pressure-fed booster, series burn with liquid oxygen phase, be continued for further study. The flyback booster study was discontinued. Both solid and liquid propelled booster vehicles with 14 by 45 foot and 15 by 60 foot payload orbiters were considered.

Five-Segment Reusable Solid Rocket Booster Upgrade

NASA Technical Reports Server (NTRS)

Sauvageau, Don

1999-01-01

The Five Segment Reusable Solid Rocket Booster (RSRB) feasibility status is presented in viewgraph form. The Five Segment Booster (FSB) objective is to provide a low cost, low risk approach to increase reliability and safety of the Shuttle system. Topics include: booster upgrade requirements; design summary; reliability issues; booster trajectories; launch site assessment; and enhanced abort modes.

30 CFR 57.8518 - Main and booster fans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

30 CFR 57.8518 - Main and booster fans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

30 CFR 57.8518 - Main and booster fans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

30 CFR 57.8518 - Main and booster fans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

30 CFR 57.8518 - Main and booster fans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Main and booster fans. 57.8518 Section 57.8518... and Underground § 57.8518 Main and booster fans. (a) All mine main and booster fans installed and used..., or adjustments. (b) In the event of main or booster fan failure due to a malfunction, accident, power...

Caste-, work-, and descent-based discrimination as a determinant of health in social epidemiology.

PubMed

Patil, Rajan R

2014-01-01

Social epidemiology explores health in the context of broad social determinants of health, where the boundary lines between health and politics appear increasingly blurred. Social determinants of health such as caste, discrimination, and social exclusion are inherently political in nature, hence it becomes imperative to look at health through a broader perspective of political philosophy, ideology, and caste that imposes enormous obstacles to a person's full attainment of civil, political, economic, social, and cultural rights. Caste is descent based and hereditary in nature. It is a characteristic determined by one's birth into a particular caste, irrespective of the faith practiced by the individual. Caste denotes a system of rigid social stratification into ranked groups defined by descent and occupation. Under various caste systems throughout the world, caste divisions also dominate in housing, marriage, and general social interaction divisions that are reinforced through the practice and threat of social ostracism, economic boycotts, and even physical violence-all of which undermine health equality.

NASA's Space Launch System: Developing the World's Most Powerful Solid Booster

NASA Technical Reports Server (NTRS)

Priskos, Alex

2016-01-01

NASA's Journey to Mars has begun. Indicative of that challenge, this will be a multi-decadal effort requiring the development of technology, operational capability, and experience. The first steps are under way with more than 15 years of continuous human operations aboard the International Space Station (ISS) and development of commercial cargo and crew transportation capabilities. NASA is making progress on the transportation required for deep space exploration - the Orion crew spacecraft and the Space Launch System (SLS) heavy-lift rocket that will launch Orion and large components such as in-space stages, habitat modules, landers, and other hardware necessary for deep-space operations. SLS is a key enabling capability and is designed to evolve with mission requirements. The initial configuration of SLS - Block 1 - will be capable of launching more than 70 metric tons (t) of payload into low Earth orbit, greater mass than any other launch vehicle in existence. By enhancing the propulsion elements and larger payload fairings, future SLS variants will launch 130 t into space, an unprecedented capability that simplifies hardware design and in-space operations, reduces travel times, and enhances the odds of mission success. SLS will be powered by four liquid fuel RS-25 engines and two solid propellant five-segment boosters, both based on space shuttle technologies. This paper will focus on development of the booster, which will provide more than 75 percent of total vehicle thrust at liftoff. Each booster is more than 17 stories tall, 3.6 meters (m) in diameter and weighs 725,000 kilograms (kg). While the SLS booster appears similar to the shuttle booster, it incorporates several changes. The additional propellant segment provides additional booster performance. Parachutes and other hardware associated with recovery operations have been deleted and the booster designated as expendable for affordability reasons. The new motor incorporates new avionics, new propellant grain, asbestos-free case insulation, a redesigned nozzle, streamlined manufacturing processes, and new inspection techniques. New materials and processes provide improved performance, safety, and affordability but also have led to challenges for the government/industry development team. The team completed its first full-size qualification motor test firing in early 2015. The second is scheduled for mid-2016. This paper will discuss booster accomplishments to date, as well as challenges and milestones ahead.

47 CFR 74.15 - Station license period.

Code of Federal Regulations, 2011 CFR

2011-10-01

... broadcast booster station or a TV broadcast booster station will be issued for a period running concurrently... broadcast station, FM translator or FM broadcast booster, TV translator or TV broadcast booster, or low...

47 CFR 74.15 - Station license period.

Code of Federal Regulations, 2012 CFR

2012-10-01

... broadcast booster station or a TV broadcast booster station will be issued for a period running concurrently... broadcast station, FM translator or FM broadcast booster, TV translator or TV broadcast booster, or low...

Hybrid propulsion technology program. Volume 2: Technology definition package

NASA Technical Reports Server (NTRS)

Jensen, Gordon E.; Holzman, Allen L.; Leisch, Steven O.; Keilbach, Joseph; Parsley, Randy; Humphrey, John

1989-01-01

A concept design study was performed to configure two sizes of hybrid boosters; one which duplicates the advanced shuttle rocket motor vacuum thrust time curve and a smaller, quarter thrust level booster. Two sizes of hybrid boosters were configured for either pump-fed or pressure-fed oxygen feed systems. Performance analyses show improved payload capability relative to a solid propellant booster. Size optimization and fuel safety considerations resulted in a 4.57 m (180 inch) diameter large booster with an inert hydrocarbon fuel. The preferred diameter for the quarter thrust level booster is 2.53 m (96 inches). The demonstration plan would culminate with test firings of a 3.05 m (120 inch) diameter hybrid booster.

Development of a New Ferrous Aluminosilicate Refractory Material for Investment Casting of Aluminum Alloys

NASA Astrophysics Data System (ADS)

Yuan, Chen; Jones, Sam; Blackburn, Stuart

2012-12-01

Investment casting is a time-consuming, labour intensive process, which produces complex, high value-added components for a variety of specialised industries. Current environmental and economic pressures have resulted in a need for the industry to improve current casting quality, reduce manufacturing costs and explore new markets for the process. Alumino-silicate based refractories are commonly used as both filler and stucco materials for ceramic shell production. A new ceramic material, norite, is now being produced based on ferrous aluminosilicate chemistry, having many potential advantages when used for the production of shell molds for casting aluminum alloy. This paper details the results of a direct comparison made between the properties of a ceramic shell system produced with norite refractories and a typical standard refractory shell system commonly used in casting industry. A range of mechanical and physical properties of the systems was measured, and a full-scale industrial casting trial was also carried out. The unique properties of the norite shell system make it a promising alternative for casting aluminum based alloys in the investment foundry.

On Macrosegregation

NASA Astrophysics Data System (ADS)

Ludwig, Andreas; Wu, Menghuai; Kharicha, Abdellah

2015-11-01

Macrosegregations, namely compositional inhomogeneities at a scale much larger than the microstructure, are typically classified according to their metallurgical appearance. In ingot castings, they are known as `A' and `V' segregation, negative cone segregation, and positive secondary pipe segregation. There exists `inverse' segregation at casting surfaces and `centerline' segregation in continuously cast slabs and blooms. Macrosegregation forms if a relative motion between the solute-enriched or -depleted melt and dendritic solid structures occurs. It is known that there are four basic mechanisms for the occurrence of macrosegregation. In the recent years, the numerical description of the combination of these mechanisms has become possible and so a tool has emerged which can be effectively used to get a deeper understanding into the process details which are responsible for the formation of the above-mentioned different macrosegregation appearances. Based on the most sophisticated numerical models, we consequently associate the four basic formation mechanisms with the physical phenomena happening during (i) DC-casting of copper-based alloys, (ii) DC-casting of aluminum-based alloys, (iii) continuous casting of steel, and (iv) ingot casting of steel.

Optimal design and operation of booster chlorination stations layout in water distribution systems.

PubMed

Ohar, Ziv; Ostfeld, Avi

2014-07-01

This study describes a new methodology for the disinfection booster design, placement, and operation problem in water distribution systems. Disinfectant residuals, which are in most cases chlorine residuals, are assumed to be sufficient to prevent growth of pathogenic bacteria, yet low enough to avoid taste and odor problems. Commonly, large quantities of disinfectants are released at the sources outlets for preserving minimum residual disinfectant concentrations throughout the network. Such an approach can cause taste and odor problems near the disinfectant injection locations, but more important hazardous excessive disinfectant by-product formations (DBPs) at the far network ends, of which some may be carcinogenic. To cope with these deficiencies booster chlorination stations were suggested to be placed at the distribution system itself and not just at the sources, motivating considerable research in recent years on placement, design, and operation of booster chlorination stations in water distribution systems. The model formulated and solved herein is aimed at setting the required chlorination dose of the boosters for delivering water at acceptable residual chlorine and TTHM concentrations for minimizing the overall cost of booster placement, construction, and operation under extended period hydraulic simulation conditions through utilizing a multi-species approach. The developed methodology links a genetic algorithm with EPANET-MSX, and is demonstrated through base runs and sensitivity analyses on a network example application. Two approaches are suggested for dealing with water quality initial conditions and species periodicity: (1) repetitive cyclical simulation (RCS), and (2) cyclical constrained species (CCS). RCS was found to be more robust but with longer computational time. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cost-Effectiveness of Adolescent Pertussis Vaccination for The Netherlands: Using an Individual-Based Dynamic Model

PubMed Central

de Vries, Robin; Kretzschmar, Mirjam; Schellekens, Joop F. P.; Versteegh, Florens G. A.; Westra, Tjalke A.; Roord, John J.; Postma, Maarten J.

2010-01-01

Background Despite widespread immunization programs, a clear increase in pertussis incidence is apparent in many developed countries during the last decades. Consequently, additional immunization strategies are considered to reduce the burden of disease. The aim of this study is to design an individual-based stochastic dynamic framework to model pertussis transmission in the population in order to predict the epidemiologic and economic consequences of the implementation of universal booster vaccination programs. Using this framework, we estimate the cost-effectiveness of universal adolescent pertussis booster vaccination at the age of 12 years in the Netherlands. Methods/Principal Findings We designed a discrete event simulation (DES) model to predict the epidemiological and economic consequences of implementing universal adolescent booster vaccination. We used national age-specific notification data over the period 1996–2000—corrected for underreporting—to calibrate the model assuming a steady state situation. Subsequently, booster vaccination was introduced. Input parameters of the model were derived from literature, national data sources (e.g. costing data, incidence and hospitalization data) and expert opinions. As there is no consensus on the duration of immunity acquired by natural infection, we considered two scenarios for this duration of protection (i.e. 8 and 15 years). In both scenarios, total pertussis incidence decreased as a result of adolescent vaccination. From a societal perspective, the cost-effectiveness was estimated at €4418/QALY (range: 3205–6364 € per QALY) and €6371/QALY (range: 4139–9549 € per QALY) for the 8- and 15-year protection scenarios, respectively. Sensitivity analyses revealed that the outcomes are most sensitive to the quality of life weights used for pertussis disease. Conclusions/Significance To our knowledge we designed the first individual-based dynamic framework to model pertussis transmission in the population. This study indicates that adolescent pertussis vaccination is likely to be a cost-effective intervention for The Netherlands. The model is suited to investigate further pertussis booster vaccination strategies. PMID:20976213

47 CFR 73.3500 - Application and report forms.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., TV Translator or TV Booster Station. 347 Application for a Low Power TV, TV Translator or TV Booster... Booster Station. 350 Application for an FM Translator or FM Booster Station License. 395-B Annual...

47 CFR 73.3500 - Application and report forms.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., TV Translator or TV Booster Station. 347 Application for a Low Power TV, TV Translator or TV Booster... Booster Station. 350 Application for an FM Translator or FM Booster Station License. 395-B Annual...

47 CFR 73.3500 - Application and report forms.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., TV Translator or TV Booster Station. 347 Application for a Low Power TV, TV Translator or TV Booster... Booster Station. 350 Application for an FM Translator or FM Booster Station License. 395-B Annual...

47 CFR 73.3500 - Application and report forms.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., TV Translator or TV Booster Station. 347 Application for a Low Power TV, TV Translator or TV Booster... Booster Station. 350 Application for an FM Translator or FM Booster Station License. 395-B Annual...

KSC-2009-1384

NASA Image and Video Library

2008-12-04

VANDENBERG AIR FORCE BASE, Calif. – On Space Launch Complex 2 at Vandenberg Air Force Base in California, a solid rocket booster is raised to vertical. The booster will be lifted into the service tower and installed on the Delta II rocket for the NOAA-N Prime satellite. NOAA-N Prime is the latest polar-orbiting operational environmental weather satellite developed by NASA for the National Oceanic and Atmospheric Administration. It is built by Lockheed Martin and similar to NOAA-N launched on May 20, 2005. Launch of NOAA-N Prime is scheduled for Feb. 4. Photo credit: NASA/Joe Davila, VAFB

Long-term persistence of protective antibodies in Dutch adolescents following a meningococcal serogroup C tetanus booster vaccination.

PubMed

van Ravenhorst, Mariëtte B; Marinovic, Axel Bonacic; van der Klis, Fiona R M; van Rooijen, Debbie M; van Maurik, Marjan; Stoof, Susanne P; Sanders, Elisabeth A M; Berbers, Guy A M

2016-12-07

Due to waning immunity, infant vaccination with meningococcal serogroup C conjugated (MenCC) vaccines is insufficient to maintain long-term individual protection. Adolescent booster vaccination is thought to offer direct protection against invasive meningococcal disease (IMD) but also to reduce meningococcal carriage and transmission and in this way establish herd protection in the population. Previously, we studied antibody levels after adolescent MenCC booster vaccination. In the present study, the adolescent vaccinees were revisited after three years to determine antibody persistence and to predict long-term protection. Meningococcal serogroup C tetanus toxoid conjugated (MenC-TT) vaccine was administered to 10-, 12- and 15-year old participants who had been primed nine years earlier with a single dose of MenC-TT vaccine. Blood samples were collected before, 1month, 1year and 3years after the adolescent booster vaccination. Functional antibody levels were measured with serum bactericidal assay using rabbit complement (rSBA). Meningococcal serogroup C polysaccharide and tetanus toxoid specific antibody levels were measured using fluorescent-bead-based multiplex immunoassay. Long-term protection was estimated using longitudinal multilevel antibody decay modeling. Of the original 268 participants, 201 (75%) were revisited after 3years. All participants still had an rSBA titer above the protective threshold of ⩾8 and 98% ⩾128. The 15-year-olds showed the highest antibody titers. Using a bi-exponential decay model, the median time to fall below the protection threshold (rSBA titer <8) was 16.3years, 45.9years and around 270years following the booster for the 10-, 12- and 15-year-olds, respectively. After a first steep decline in antibody levels in the first year after the booster, antibody levels slowly declined between one and three years post-booster. A routine MenC-TT booster vaccination for adolescents in the Netherlands will likely provide long-term individual protection and potentially reduce the risk of resurgence of MenC disease in the general population. Copyright © 2016 Elsevier Ltd. All rights reserved.

Salivary antibody levels in adolescents in response to a meningococcal serogroup C conjugate booster vaccination nine years after priming: systemically induced local immunity and saliva as potential surveillance tool.

PubMed

Stoof, Susanne P; van der Klis, Fiona R M; van Rooijen, Debbie M; Bogaert, Debby; Trzciński, Krzysztof; Sanders, Elisabeth A M; Berbers, Guy A M

2015-07-31

In several countries large-scale immunization of children and young adults with Meningococcal serogroup C (MenC) conjugate vaccines has induced long-standing herd protection. Salivary antibodies may play an important role in mucosal protection against meningococcal acquisition and carriage. To investigate antibody levels in (pre)adolescents primed 9 years earlier with a single dose of MenC-polysaccharide tetanus toxoid conjugated (MenC-TT) vaccine and the response to a booster vaccination, with special focus on age-related differences and the relation between salivary and serum antibody levels. Nine years after priming, healthy 10- (n=91), 12- (n=91) and 15-year-olds (n=86) received a MenC-TT booster vaccination. Saliva and serum samples were collected prior to and 1 month and 1 year after vaccination. MenC-polysaccharide(MenC-PS)-specific antibody levels were measured using a fluorescent-bead-based multiplex immunoassay. Before the booster, MenC-PS-specific IgG and IgA levels in saliva and serum were low and correlated with age at priming. The booster induced a marked increase in salivary MenC-PS-specific IgG (>200-fold), but also in IgA (∼10-fold). One year after the booster, salivary IgG and IgA had remained above pre-booster levels in all age groups (∼20-fold and ∼3-fold, respectively), with persistence of highest levels in the 15-year-olds. MenC-PS-specific IgG and IgA levels in saliva strongly correlated with the levels in serum. Parenteral MenC-TT booster vaccination induces a clear increase in salivary MenC-PS-specific IgG and IgA levels and persistence of highest levels correlates with age. The strong correlation between serum and salivary antibody levels indicate that saliva may offer an easy and reliable tool for future antibody surveillance. Copyright © 2015 Elsevier Ltd. All rights reserved.

Modeling the long-term persistence of hepatitis A antibody after a two-dose vaccination schedule in Argentinean children.

PubMed

López, Eduardo L; Contrini, María Marta; Mistchenko, Alicia; Kieffer, Alexia; Baggaley, Rebecca F; Di Tanna, Gian Luca; Desai, Kamal; Rasuli, Anvar; Armoni, Judith

2015-04-01

Long-term seroprotection data are essential for decision-making on the need and timing of vaccine boosters. Based on data from longitudinal serological studies, modeling can provide estimates on long-term antibody persistence and inform such decision-making. We examined long-term anti-hepatitis A virus (anti-HAV) antibody persistence in Argentinean children ≤15 years after the initial study where they completed a 2-dose course of inactivated hepatitis A vaccine (Avaxim 80U Pediatric, Sanofi Pasteur, Lyon, France). Blood serum samples were taken at baseline, 2 weeks (post first dose), 6 months (pre-booster), 6.5 months (post-booster), 10 years and 14-15 years after first vaccine dose. We fitted 8 statistical model types, predominantly mixed effects models, to anti-HAV persistence data, to identify the most appropriate and best fitting models for our data set and to predict individuals' anti-HAV levels and seroprotection rates up to 30 years post vaccination. Fifty-four children (mean age at enrollment 30.4 months) were enrolled up to 15 years post first vaccine dose. There were 3 distinct periods of antibody concentration: rapid rise up to peak concentration post-booster, rapid decay from post-booster to 10 years, followed by slower decay. A 3-segmented linear mixed effects model was the most appropriate for the data set. Extrapolating based on the available 14-15-year follow-up, the analysis predicted that 88% of individuals anti-HAV seronegative prior to vaccination would remain seroprotected at 30 years post vaccination and lifelong seroprotection for vaccinees seropositive prior to vaccination. Currently available data demonstrate that Avaxim 80U Pediatric confers to most vaccinees a high level of seroprotection against hepatitis A infection for at least 20-30 years.

KSC-2009-2144

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – The Solid Rocket Booster Retrieval Ship Liberty Star tows a booster to the dock at Hangar AF at Cape Canaveral Air Force Station in Florida. The booster was used during space shuttle Discovery's launch from NASA's Kennedy Space Center in Florida March 15 on mission STS-119. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-2009-2141

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – The Solid Rocket Booster Retrieval Ship Liberty Star tows a booster to the dock at Hangar AF at Cape Canaveral Air Force Station in Florida. The booster was used during space shuttle Discovery's launch from NASA's Kennedy Space Center in Florida March 15 on mission STS-119. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

Pressure-Equalizing Cradle for Booster Rocket Mounting

NASA Technical Reports Server (NTRS)

Rutan, Elbert L. (Inventor)

2015-01-01

A launch system and method improve the launch efficiency of a booster rocket and payload. A launch aircraft atop which the booster rocket is mounted in a cradle, is flown or towed to an elevation at which the booster rocket is released. The cradle provides for reduced structural requirements for the booster rocket by including a compressible layer, that may be provided by a plurality of gas or liquid-filled flexible chambers. The compressible layer contacts the booster rocket along most of the length of the booster rocket to distribute applied pressure, nearly eliminating bending loads. Distributing the pressure eliminates point loading conditions and bending moments that would otherwise be generated in the booster rocket structure during carrying. The chambers may be balloons distributed in rows and columns within the cradle or cylindrical chambers extending along a length of the cradle. The cradle may include a manifold communicating gas between chambers.

Factors Affecting Booster Seat Use.

PubMed

Aita-Levy, Jerussa; Henderson, Lauren

2016-10-01

Objective To identify general awareness of booster seats as well as reasons for use and nonuse in an urban pediatric emergency room. Methods A total of 100 questionnaires were completed consisting of 24 questions each. Questions included knowledge of booster seat guidelines, source of knowledge, awareness of risks, and confidence in booster seats. Afterward, participants were provided an educational handout. Results Majority of parents reported currently using or having used a booster seat. The most popular reason was to protect from injury (78%), and reason for nonuse was size (44%). Majority of parents agreed that motor vehicle crashes were the leading cause of death in children. However, 56% of parents prematurely transitioned child out of a booster seat. Only 20% reported learning about booster seats from their pediatrician. Conclusion Parents continue to transition their children prematurely from booster seats. Current state laws need revision as well as further education using simplified illustrated guidelines. © The Author(s) 2015.

Misuse of booster cushions among children and adults in Shanghai-an observational and attitude study during buckling up.

PubMed

Bohman, Katarina; Jorlöv, Sofia; Zhou, Shengqi; Zhao, Cloud; Sui, Bo; Ding, Chengkai

2016-10-02

Traffic crashes are one of the leading causes of fatalities among Chinese children. Booster cushion usage in China is low, and there are no studies showing how a population with limited experience handles booster cushions during buckling up. The purpose of this study was to evaluate the handling of and explore the attitudes toward booster cushions among children, parents, and grandparents in Shanghai. An observational study including a convenience sample of 254 children aged 4-12 years was conducted in 2 passenger cars at a shopping center in Shanghai. Parents, grandparents, or the children themselves buckled up the child on 2 types of booster cushions, a 2-stage integrated booster cushion (IBC) and an aftermarket booster cushion (BC). The test participants were observed during buckling up, first without and then with instructions. The test leaders conducted structured interviews. Ninety-eight percent of the uninstructed participants failed to buckle up without identified misuse on the aftermarket booster cushion and 31% of those uninstructed on the integrated booster cushion. The majority of misuse was severe, including placing the belt behind the arm and the lap belt routing above the guiding loops. Instruction reduced misuse to 58% (BC) and 12% (IBC), respectively, and, in particular, severe misuse. Some misuse was related to limited knowledge of how to buckle up on the booster cushion, and some misuse was intentional in order to reduce discomfort. The participants, both children and adults, reported that they preferred the IBC due to good comfort and convenience. Safety was reported as the main reason for adults using booster cushions in general, whereas children reported comfort as the most important motivation. Education is needed to ensure frequent and correct use of booster cushions in China and to raise safety awareness among children and adults. Furthermore, it is important that the booster cushions offer intuitively correct usage to a population with limited experience of booster cushions. This is the first study published on the handling of and attitude toward booster cushions after child restraints laws were introduced in Shanghai 2014.

NASA's Space Launch System Advanced Booster Engineering Demonstration and/or Risk Reduction Efforts

NASA Technical Reports Server (NTRS)

Crumbly, Christopher M.; Dumbacher, Daniel L.; May, Todd A.

2012-01-01

The National Aeronautics and Space Administration (NASA) formally initiated the Space Launch System (SLS) development in September 2011, with the approval of the program s acquisition plan, which engages the current workforce and infrastructure to deliver an initial 70 metric ton (t) SLS capability in 2017, while using planned block upgrades to evolve to a full 130 t capability after 2021. A key component of the acquisition plan is a three-phased approach for the first stage boosters. The first phase is to complete the development of the Ares and Space Shuttle heritage 5-segment solid rocket boosters (SRBs) for initial exploration missions in 2017 and 2021. The second phase in the booster acquisition plan is the Advanced Booster Risk Reduction and/or Engineering Demonstration NASA Research Announcement (NRA), which was recently awarded after a full and open competition. The NRA was released to industry on February 9, 2012, with a stated intent to reduce risks leading to an affordable advanced booster and to enable competition. The third and final phase will be a full and open competition for Design, Development, Test, and Evaluation (DDT&E) of the advanced boosters. There are no existing boosters that can meet the performance requirements for the 130 t class SLS. The expected thrust class of the advanced boosters is potentially double the current 5-segment solid rocket booster capability. These new boosters will enable the flexible path approach to space exploration beyond Earth orbit (BEO), opening up vast opportunities including near-Earth asteroids, Lagrange Points, and Mars. This evolved capability offers large volume for science missions and payloads, will be modular and flexible, and will be right-sized for mission requirements. NASA developed the Advanced Booster Engineering Demonstration and/or Risk Reduction NRA to seek industry participation in reducing risks leading to an affordable advanced booster that meets the SLS performance requirements. Demonstrations and/or risk reduction efforts were required to be related to a proposed booster concept directly applicable to fielding an advanced booster. This paper will discuss, for the first time publicly, the contract awards and how NASA intends to use the data from these efforts to prepare for the planned advanced booster DDT&E acquisition as the SLS Program moves forward with competitively procured affordable performance enhancements.

NASA's Space Launch System Advanced Booster Engineering Demonstration and Risk Reduction Efforts

NASA Technical Reports Server (NTRS)

Crumbly, Christopher M.; May, Todd; Dumbacher, Daniel

2012-01-01

The National Aeronautics and Space Administration (NASA) formally initiated the Space Launch System (SLS) development in September 2011, with the approval of the program s acquisition plan, which engages the current workforce and infrastructure to deliver an initial 70 metric ton (t) SLS capability in 2017, while using planned block upgrades to evolve to a full 130 t capability after 2021. A key component of the acquisition plan is a three-phased approach for the first stage boosters. The first phase is to complete the development of the Ares and Space Shuttle heritage 5-segment solid rocket boosters for initial exploration missions in 2017 and 2021. The second phase in the booster acquisition plan is the Advanced Booster Risk Reduction and/or Engineering Demonstration NASA Research Announcement (NRA), which was recently awarded after a full and open competition. The NRA was released to industry on February 9, 2012, and its stated intent was to reduce risks leading to an affordable Advanced Booster and to enable competition. The third and final phase will be a full and open competition for Design, Development, Test, and Evaluation (DDT&E) of the Advanced Boosters. There are no existing boosters that can meet the performance requirements for the 130 t class SLS. The expected thrust class of the Advanced Boosters is potentially double the current 5-segment solid rocket booster capability. These new boosters will enable the flexible path approach to space exploration beyond Earth orbit, opening up vast opportunities including near-Earth asteroids, Lagrange Points, and Mars. This evolved capability offers large volume for science missions and payloads, will be modular and flexible, and will be right-sized for mission requirements. NASA developed the Advanced Booster Engineering Demonstration and/or Risk Reduction NRA to seek industry participation in reducing risks leading to an affordable Advanced Booster that meets the SLS performance requirements. Demonstrations and/or risk reduction efforts were required to be related to a proposed booster concept directly applicable to fielding an Advanced Booster. This paper will discuss, for the first time publicly, the contract awards and how NASA intends to use the data from these efforts to prepare for the planned Advanced Booster DDT&E acquisition as the SLS Program moves forward with competitively procured affordable performance enhancements.

Long-term immunogenicity of an initial booster dose of an inactivated, Vero cell culture-derived Japanese encephalitis vaccine (JE-VC) and the safety and immunogenicity of a second JE-VC booster dose in children previously vaccinated with an inactivated, mouse brain-derived Japanese encephalitis vaccine.

PubMed

Yun, Ki Wook; Lee, Hoan Jong; Park, Ji Young; Cho, Hye-Kyung; Kim, Yae-Jean; Kim, Kyung-Hyo; Kim, Nam Hee; Hong, Young Jin; Kim, Dong Ho; Kim, Hwang Min; Cha, Sung-Ho

2018-03-07

This study was performed with the aim of determining the long-term immunogenicity of an inactivated, Vero cell culture-derived Japanese encephalitis (JE) vaccine (JE-VC) and an inactivated, mouse brain-derived JE vaccine (JE-MB) after the 1st booster dose at 2 years of age, as well as the safety and immunogenicity of the 2nd booster dose of JE-VC at 6 years of age, in children primed and given a 1st booster dose of either JE-VC or JE-MB. In this multicenter, open-label clinical trial, the study population consisted of healthy Korean children (aged 6 years) who participated in the previous JE vaccine trial. All subjects were subcutaneously vaccinated once for the booster immunization with Boryung Cell Culture Japanese Encephalitis Vaccine® (JE-VC). Approximately 4 years after the 1st booster dose of JE-VC, the seroprotection rate (SPR) and geometric mean titer (GMT) of the neutralizing antibody were 100% and 1113.8, respectively. In children primed and given a 1st booster dose of JE-MB, the SPR and GMT were 88.5% and 56.3, respectively. After the 2nd booster dose of JE-VC, all participants primed and given a 1st booster dose of either JE-MB or JE-VC were seroprotective against JE virus. The GMT of the neutralizing antibody was higher in children primed and given a 1st booster dose of JE-VC (8144.1) than in those primed and given a 1st booster dose of JE-MB (942.5) after the vaccination (p < 0.001). In addition, the 2nd booster dose of JE-VC showed a good safety profile with no serious vaccine-related adverse events. The 1st booster dose of JE-VC and JE-MB showed long-term immunogenicity of at least 4 years, and the 2nd booster dose of JE-VC showed a good safety and immunogenicity profile in children primed and given a 1st booster dose of either JE-VC or JE-MB. ClinicalTtrials.gov Identifier: NCT02532569. Copyright © 2018 Elsevier Ltd. All rights reserved.

KSC-08pd0736

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, motors through Port Canaveral with a solid rocket booster alongside. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0741

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, nears Hangar AF at Cape Canaveral Air Force Station with a solid rocket booster alongside. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0738

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, crosses through the drawbridge over the Haulover Canal into the Banana River. The ship is towing a solid rocket booster alongside. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0740

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, tows a solid rocket booster alongside, heading for Hangar AF at Cape Canaveral Air Force Station. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0737

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, motors through Port Canaveral with a solid rocket booster alongside. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

Study of solid rocket motors for a space shuttle booster. Appendix D: Recovery and reuse 156-inch diameter solid rocket motor booster

NASA Technical Reports Server (NTRS)

1972-01-01

The baseline for a space shuttle configuration utilizing two parallel-burn, 156-in.-diameter SRMs with three segments and techroll seal movable nozzles is presented. The concept and general economic benefits of SRM recovery are equally valid for the series-burn SRMs, provided that those SRMs are also designed for the same strength, stiffness, segmentation, and interchangeability as the present design, and that those SRMs are also recovered as individual units. Feasibility studies were initiated to investigate SRM recoverability. These studies were based upon recovery of the SRM boosters for the Titan 3C. Ground rules precluded SRM modification that required significant changes in motor qualification or schedule. Even with this restriction, the study determined that the recoverable booster concept was completely feasible, both technically and economically. Parachute recovery has been selected as the best method, principally because it can accomplish the task with a minimum development cost and time to achieve operational recovery status. This system affords the highest probability for achieving large cost reductions.

Technical report analysis and design: Study of solid rocket motors for a space shuttle booster, volume 2, book 1, supplement 1

NASA Technical Reports Server (NTRS)

1972-01-01

An analysis and design effort was conducted as part of the study of solid rocket motor for a space shuttle booster. The 156-inch-diameter, parallel burn solid rocket motor was selected as its baseline because it is transportable and is the most cost-effective, reliable system that has been developed and demonstrated. The basic approach was to concentrate on the selected baseline design, and to draw from the baseline sufficient data to describe the alternate approaches also studied. The following conclusions were reached with respect to technical feasibility of the use of solid rocket booster motors for the space shuttle vehicle: (1) The 156-inch, parallel-burn baseline SRM design meets NASA's study requirements while incorporating conservative safety factors. (2) The solid rocket motor booster represents a cost-effective approach. (3) Baseline costs are conservative and are based on a demonstrated design. (4) Recovery and reuse are feasible and offer substantial cost savings. (5) Abort can be accomplished successfully. (6) Ecological effects are acceptable.

Space Launch System NASA Research Announcement Advanced Booster Engineering Demonstration and/or Risk Reduction

NASA Technical Reports Server (NTRS)

Crumbly, Christopher M.; Craig, Kellie D.

2011-01-01

The intent of the Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) effort is to: (1) Reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS (2) Enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. Key Concepts (1) Offerors must propose an Advanced Booster concept that meets SLS Program requirements (2) Engineering Demonstration and/or Risk Reduction must relate to the Offeror s Advanced Booster concept (3) NASA Research Announcement (NRA) will not be prescriptive in defining Engineering Demonstration and/or Risk Reduction

StarBooster Demonstrator Cluster Configuration Analysis/Verification Program

NASA Technical Reports Server (NTRS)

DeTurris, Dianne J.

2003-01-01

In order to study the flight dynamics of the cluster configuration of two first stage boosters and upper-stage, flight-testing of subsonic sub-scale models has been undertaken using two glideback boosters launched on a center upper-stage. Three high power rockets clustered together were built and flown to demonstrate vertical launch, separation and horizontal recovery of the boosters. Although the boosters fly to conventional aircraft landing, the centerstage comes down separately under its own parachute. The goal of the project has been to collect data during separation and flight for comparison with a six degree of freedom simulation. The configuration for the delta wing canard boosters comes from a design by Starcraft Boosters, Inc. The subscale rockets were constructed of foam covered in carbon or fiberglass and were launched with commercially available solid rocket motors. The first set of boosters built were 3-ft tall with a 4-ft tall centerstage, and two additional sets of boosters were made that were each over 5-ft tall with a 7.5 ft centerstage. The rocket cluster is launched vertically, then after motor bum out the boosters are separated and flown to a horizontal landing under radio-control. An on-board data acquisition system recorded data during both the launch and glide phases of flight.

KSC-08pd3731

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – NASA's Solid Rocket Booster Retrieval Ship Freedom Star arrives at the dock at Hangar AF, Cape Canaveral Air Force Station in Florida, with a spent solid rocket booster alongside. The booster is from space shuttle Endeavour's launch Nov. 14 on mission STS-126. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd0263

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- The solid rocket booster retrieval ship Freedom Star is temporarily docked at Port Canaveral while the booster it was towing is moved alongside for the remainder of the trip upriver to Cape Canaveral Air Force Station. Freedom Star retrieved the booster after the launch of space shuttle Atlantis' STS-122 mission. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0262

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- The solid rocket booster retrieval ship Freedom Star is temporarily docked at Port Canaveral while the booster it was towing is moved alongside for the remainder of the trip upriver to Cape Canaveral Air Force Station. Freedom Star retrieved the booster after the launch of space shuttle Atlantis' STS-122 mission. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

InSight Atlas V Booster Transport

NASA Image and Video Library

2018-03-02

A United Launch Alliance Atlas V booster is transported to Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

Athena: Advanced air launched space booster

NASA Astrophysics Data System (ADS)

Booker, Corey G.; Ziemer, John; Plonka, John; Henderson, Scott; Copioli, Paul; Reese, Charles; Ullman, Christopher; Frank, Jeremy; Breslauer, Alan; Patonis, Hristos

1994-06-01

The infrastructure for routine, reliable, and inexpensive access of space is a goal that has been actively pursued over the past 50 years, but has yet not been realized. Current launch systems utilize ground launching facilities which require the booster vehicle to plow up through the dense lower atmosphere before reaching space. An air launched system on the other hand has the advantage of being launched from a carrier aircraft above this dense portion of the atmosphere and hence can be smaller and lighter compared to its ground based counterpart. The goal of last year's Aerospace Engineering Course 483 (AE 483) was to design a 227,272 kg (500,000 lb.) air launched space booster which would beat the customer's launch cost on existing launch vehicles by at least 50 percent. While the cost analysis conducted by the class showed that this goal could be met, the cost and size of the carrier aircraft make it appear dubious that any private company would be willing to invest in such a project. To avoid this potential pitfall, this year's AE 483 class was to design as large an air launched space booster as possible which can be launched from an existing or modification to an existing aircraft. An initial estimate of the weight of the booster is 136,363 kg (300,000 lb.) to 159,091 kg (350,000 lb.).

Athena: Advanced air launched space booster

NASA Technical Reports Server (NTRS)

Booker, Corey G.; Ziemer, John; Plonka, John; Henderson, Scott; Copioli, Paul; Reese, Charles; Ullman, Christopher; Frank, Jeremy; Breslauer, Alan; Patonis, Hristos

1994-01-01

The infrastructure for routine, reliable, and inexpensive access of space is a goal that has been actively pursued over the past 50 years, but has yet not been realized. Current launch systems utilize ground launching facilities which require the booster vehicle to plow up through the dense lower atmosphere before reaching space. An air launched system on the other hand has the advantage of being launched from a carrier aircraft above this dense portion of the atmosphere and hence can be smaller and lighter compared to its ground based counterpart. The goal of last year's Aerospace Engineering Course 483 (AE 483) was to design a 227,272 kg (500,000 lb.) air launched space booster which would beat the customer's launch cost on existing launch vehicles by at least 50 percent. While the cost analysis conducted by the class showed that this goal could be met, the cost and size of the carrier aircraft make it appear dubious that any private company would be willing to invest in such a project. To avoid this potential pitfall, this year's AE 483 class was to design as large an air launched space booster as possible which can be launched from an existing or modification to an existing aircraft. An initial estimate of the weight of the booster is 136,363 kg (300,000 lb.) to 159,091 kg (350,000 lb.).

[Results of Booster Vaccination in Children with Primary Vaccine Failure after Initial Varicella Vaccination].

PubMed

Ozakiv, Takao; Nishimura, Naoko; Gotoh, Kensei; Funahashi, Keiji; Yoshii, Hironori; Okuno, Yoshinobu

2016-05-01

In October 2014, the varicella vaccination policy in Japan was changed from a single voluntary inoculation to two routine inoculations. This paper reports the results of booster vaccination in children who did not show seroconversion after initial vaccination (i.e., primary vaccine failure : PVF) over a 7-year period prior to the introduction of routine varicella vaccination. Between November 2007 and May 2014, 273 healthy children aged between 1.1 and 14.5 years (median : 1.7 years) underwent varicella vaccination. Before and 4 to 6 weeks after vaccination, the antibody titers were measured using an immune adherence hemagglutination (IAHA) assay and a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). In addition, side reactions were examined during the four-week period after vaccination. Children who did not show IAHA seroconversion (PVF) were recommended to receive a booster vaccination, and the measurement of antibody titers and an assessment of side reactions were performed after the booster dose. In May 2015, a questionnaire was mailed to each of the 273 participants to investigate whether they had developed varicella and/or herpes zoster after vaccination. After initial vaccination, the IAHA seroconversion rate was 75% and the mean antibody titer (Log2) with seroconversion was 4.7, while the gpELISA seroconversion rate was 84% and the mean antibody titer (Log10) with seroconversion was 2.4. Among children with PVF, 54 received booster vaccination within 81 to 714 days (median : 139 days) after the initial vaccination. After booster vaccination, the IAHA seroconversion rate was 98% and the mean antibody titer (Log2) with seroconversion was 5.8. Both the seroconversion rate and the antibody titer were higher compared with the values after the initial vaccination (p < 0.01). After booster vaccination, the gpELISA seropositive rate was 100% and the mean positive antibody titer (Log 10) was 3.6 ; similar results were obtained for the IAHA assay, with a significantly higher, antibody response than that after the initial vaccination (p < 0.01). Side reactions were generally minor, including fever (≥ 37.5 degrees C), rash at the injection site, and rash at other sites. There were no significant differences in the incidences of side reactions between the initial and booster vaccinations. A total of 185 participants responded to the questionnaire (response rate : 68%), and the period between receiving the initial vaccination and their response to the questionnaire ranged from 1.0 to 7.5 years (median : 4.0 years). The prevalence of breakthrough varicella after the initial vaccination was 17% among seroconverters who did not receive booster vaccination and 14% among non-seroconverters who received booster vaccination, showing no significant difference between the two groups. In conclusion, there are no safety issues regarding the administration of a booster vaccination to children with PVF after an initial varicella vaccination, and,a good antibody response can be expected.

Expendable second stage reusable space shuttle booster. Volume 2: Technical summary. Book 3: Booster vehicle modifications and ground systems definition

NASA Technical Reports Server (NTRS)

1972-01-01

A definition of the expendable second stage and space shuttle booster separation system is presented. Modifications required on the reusable booster for expendable second stage/payload flight and the ground systems needed to operate the expendable second stage in conjuction with the space shuttle booster are described. The safety, reliability, and quality assurance program is explained. Launch complex operations and services are analyzed.

Detection of canine astrovirus in dogs with diarrhea in Japan.

PubMed

Takano, Tomomi; Takashina, Midori; Doki, Tomoyoshi; Hohdatsu, Tsutomu

2015-06-01

Canine astrovirus (CAstV) is the causative agent of gastroenteritis in dogs. We collected rectal swabs from dogs with or without diarrhea symptoms in Japan and examined the feces for the presence of CAstV by RT-PCR with primers based on a conserved region of the ORF1b gene. The ORF1b gene of CAstV was not detected in the 42 dogs without clinical illness but was present in three pups out of the 31 dogs with diarrhea symptoms. Based on the full-length capsid protein, the CAstV KU-D4-12 strain that we detected in this study shared high homology with the novel virulent CAstV VM-2011 strain.

Maintaining the potential of a psycho-educational program: efficacy of a booster session after an intervention offered family caregivers at disclosure of a relative's dementia diagnosis.

PubMed

Ducharme, Francine; Lachance, Lise; Lévesque, Louise; Zarit, Steven Howard; Kergoat, Marie-Jeanne

2015-01-01

Booster sessions as a means of maintaining the benefits of psycho-educational programs have received little attention in caregiving research. Caregivers were offered a booster session following participation in a program entitled Learning to Become a Family Caregiver (LBFC) intended to facilitate transition to the caregiver role after diagnostic disclosure of dementia in a relative. The 90-minute booster session served to review program content and afforded the opportunity to discuss and practice learned skills. This study sought to test the efficacy of the booster session in maintaining or recovering program effects at six months post-program. Participants in the program were randomly assigned to a group that received the booster session (n = 31) or a group that did not (n = 29). A third control group was also formed, which continued to receive only the usual care provided in memory clinics. Eligible participants - French-speaking primary caregivers of a relative diagnosed with Alzheimer's in the past nine months - were recruited in memory clinics in Quebec (Canada). Participants were blindly assessed before randomization and six months after the booster session on outcomes associated with a healthy role transition. Prediction analyses revealed one significant positive effect of the booster session: emergence of preparedness to provide care. Moreover, with or without the booster session, the program continued to have a positive effect on psychological distress and contributed to the emergence of self-efficacy in dealing with caregiving situations. The booster session had no significant effect on knowledge of services, planning for future care needs, use of reframing as a coping strategy, perceived informal support, and family conflicts. The limited effect observed is discussed in terms of the booster session's content and intensity. Recommendations are made for designing future research on the effect of booster sessions, including the importance of including a placebo booster group.

47 CFR 22.527 - Signal boosters.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal... additional transmitters for existing systems. Licensees must not allow any signal booster that they operate...

47 CFR 22.527 - Signal boosters.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal... additional transmitters for existing systems. Licensees must not allow any signal booster that they operate...

47 CFR Alphabetical Index - Part 74

Code of Federal Regulations, 2014 CFR

2014-10-01

... FM Broadcast Booster Stations FM translator and booster station information available on the Internet..., Directional (Aural STL/Relays) 74.536 Antenna location— LPTV/TV Translator 74.737 FM Translators/Boosters 74....902 FM Translators/Boosters 74.1202 Authorization of equipment— Aural Auxiliary 74.550 Remote Pickup...

47 CFR Alphabetical Index - Part 74

Code of Federal Regulations, 2013 CFR

2013-10-01

... FM Broadcast Booster Stations FM translator and booster station information available on the Internet..., Directional (Aural STL/Relays) 74.536 Antenna location— LPTV/TV Translator 74.737 FM Translators/Boosters 74....902 FM Translators/Boosters 74.1202 Authorization of equipment— Aural Auxiliary 74.550 Remote Pickup...

47 CFR 24.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 24.9... PERSONAL COMMUNICATIONS SERVICES General Information § 24.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated...

47 CFR 24.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 24.9... PERSONAL COMMUNICATIONS SERVICES General Information § 24.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated...

47 CFR Alphabetical Index - Part 74

Code of Federal Regulations, 2012 CFR

2012-10-01

... FM Broadcast Booster Stations FM translator and booster station information available on the Internet..., Directional (Aural STL/Relays) 74.536 Antenna location— LPTV/TV Translator 74.737 FM Translators/Boosters 74....902 FM Translators/Boosters 74.1202 Authorization of equipment— Aural Auxiliary 74.550 Remote Pickup...

Do parental decision-making patterns predict compliance with use of child booster seats?

PubMed

Shimony-Kanat, Sarit; Gofin, Rosa; Kienski Woloski Wruble, Anna C; Mann, Leon

2018-03-01

Booster seat use for 4-9 year olds remains the lowest of all age groups in many countries. The objective of this study is to examine whether parents' decision-making patterns, as measured by the Melbourne Decision Making Questionnaire, relate to car booster seat use. Israeli parents of 4-7 years old children (n = 398) answered a questionnaire about car safety and decision-making habits. Ninety per cent of parents reported having a booster seat; 70.5% reported consistent booster seat use in general and on short drives during the last month (booster seat use compliance index). Greater compliance index was positively related to a vigilant decision-making pattern, passenger compliance with rear seat belts and families with fewer children. Lower booster seat use compliance index was associated with buck-passing decision-making pattern. Health professionals and policy-makers should take into account parents' habitual decision-making patterns when designing interventions for car booster seat compliance.

Prevention of illicit drug use through a school-based program: results of a longitudinal, cluster-randomized controlled trial.

PubMed

Guo, Jong-Long; Lee, Tzu-Chi; Liao, Jung-Yu; Huang, Chiu-Mieh

2015-03-01

To evaluate the long-term effects of an illicit drug use prevention program for adolescents that integrates life skills into the theory of planned behavior. We conducted a cluster-randomized trial in which 24 participating schools were randomized to either an intervention group (12 schools, n = 1,176 students) or a control group (12 schools, n = 915 students). Participants were grade 7 students. The intervention comprised a main intervention of 10 sessions and two booster interventions. Booster 1 (four sessions) and booster 2 (two sessions) were performed at 6 months and 12 months, respectively, after completion of the main intervention. Assessments were made at baseline, after the main intervention, and after each booster session using specific questionnaires for measuring participants' attitudes, subjective norms, perceived behavioral control, and life skills. Retention rates were 71.9% (845/1,176) in the intervention group and 90.7% (830/915) in the control group after the 12-month follow-up. A significantly lower proportion of intervention group participants reported illicit drug use after the first and second booster sessions compared with control group participants (.1% vs. 1.7% and .2% vs. 1.7%, respectively; both p < .05). Attitudes, subjective norms, perceived behavioral control, life skills, and behavioral intention scores of the intervention group were significantly higher than those of control group after the first and second booster sessions (all p < .001), suggesting that intervention group students tended to avoid drug use. A drug use prevention program integrating life skills into the theory of planned behavior may be effective for reducing illicit drug use and improving planned behavior-related constructs in adolescents. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

KSC-99pp0532

NASA Image and Video Library

1999-05-16

KENNEDY SPACE CENTER, FLA. -- Casting a giant shadow across the crawlerway, a crawler transporter slowly maneuvers Space Shuttle Discovery, with its external tank and solid rocket boosters, toward High Bay 1 of the Vehicle Assembly Building to repair damage to the external tank's foam insulation caused by hail. The necessary repair work could not be performed at Pad 39B due to limited access to the damaged areas. The work is expected to take two to three days, allowing Discovery to roll back to the pad by midweek for launch of mission STS-96, the 94th launch in the Space Shuttle Program. This is only the 13th time since 1981 that a Shuttle has had to roll back from the pad. Liftoff will occur no earlier than May 27. STS-96 is a logistics and resupply mission for the International Space Station, carrying such payloads as a Russian crane, the Strela; a U.S.-built crane; the Spacehab Oceaneering Space System Box (SHOSS), a logistics items carrier; and STARSHINE, a student-shared experiment

NASA's Space Launch System Takes Shape

NASA Technical Reports Server (NTRS)

Askins, Bruce R.; Robinson, Kimberly F.

2017-01-01

Significant hardware and software for NASA's Space Launch System (SLS) began rolling off assembly lines in 2016, setting the stage for critical testing in 2017 and the launch of new capability for deep-space human exploration. (Figure 1) At NASA's Michoud Assembly Facility (MAF) near New Orleans, LA, full-scale test articles are being joined by flight hardware. Structural test stands are nearing completion at NASA's Marshall Space Flight Center (MSFC), Huntsville, AL. An SLS booster solid rocket motor underwent test firing, while flight motor segments were cast. An RS-25 and Engine Control Unit (ECU) for early SLS flights were tested at NASA's Stennis Space Center (SSC). The upper stage for the first flight was completed, and NASA completed Preliminary Design Review (PDR) for a new, powerful upper stage. The pace of production and testing is expected to increase in 2017. This paper will discuss the technical and programmatic highlights and challenges of 2016 and look ahead to plans for 2017.

Aerodynamic characteristics of a 142-inch diameter solid rocket booster, configuration 139 (SA2FA/SA2FB)

NASA Technical Reports Server (NTRS)

Radford, W. D.; Johnson, J. D.

1974-01-01

Tests of a 2.112 percent scale model of the space shuttle solid rocket booster model were conducted in a transonic pressure tunnel. Tests were conducted at Mach numbers ranging from 0.4 to 1.2, angles of attack from minus one degree to plus 181 degrees, and Reynolds numbers from 0.6 million to 6.1 million per foot. The model configurations investigated were as follows: (1) solid rocket booster without external protuberances, (2) solid rocket booster with an electrical tunnel and a solid rocket booster/external tank thrust attachment structure, and (3) solid rocket booster with two body strakes.

Hypersonic aerothermal characteristics of a manned low finenes ratio shuttle booster

NASA Technical Reports Server (NTRS)

Bernot, P. T.; Throckmorton, D. A.

1972-01-01

An investigation of a winged booster model having canards and an ascent configuration comprised of the booster mounted in tandem with an orbiter model has been conducted at Mach 10.2 in the continuous flow hypersonic tunnel. Longitudinal and lateral directional force characteristics were obtained over angle of attack ranges of -12 deg to 60 deg for the booster and -11 deg to 11 deg for the ascent configuration. Interference heating effects on the booster using the phase-change coating technique were determined at 0 deg angle of attack. Some oil flow photographs of the isolated booster and orbiter and ascent configuration are also presented.

Analysis of the staging maneuver and booster glideback guidance for a two-stage, winged, fully reusable launch vehicle. M.S. Thesis - George Washington Univ.

NASA Technical Reports Server (NTRS)

Naftel, J. Christopher; Powell, Richard W.

1993-01-01

One of the promising launch concepts that could replace the current space shuttle launch system is a two-stage, winged, vertical-takeoff, fully reusable launch vehicle. During the boost phase of ascent, the booster provides propellant for the orbiter engines through a cross-feed system. When the vehicle reaches a Mach number of 3, the booster propellants are depleted and the booster is staged and glides unpowered to a horizontal landing at a launch site runway. Two major design issues for this class of vehicle are the staging maneuver and the booster glideback. For the staging maneuver analysis, a technique was developed that provides for a successful separation of the booster from the orbiter over a wide range of staging angles of attack. A longitudinal flight control system was developed for control of the booster during the staging maneuver. For the booster glide back analysis, a guidance algorithm was developed that successfully guides the booster from the completion of the staging maneuver to a launch site runway while encountering many off-nominal atmospheric, aerodynamic, and staging conditions.

Theoretical Analysis and Bench Tests of a Control-Surface Booster Employing a Variable Displacement Hydraulic Pump

NASA Technical Reports Server (NTRS)

Mathews, Charles W.; Kleckner, Harold F.

1947-01-01

The NACA is conducting a general investigation of servo-mechanisms for use in powering aircraft control surfaces. This paper presents a theoretical analysis and the results of bench tests of a control-booster system which employs a variable displacement hydraulic pump. The booster is intended for use in a flight investigation to determine the effects of various booster parameters on the handling qualities of airplanes. Such a flight investigation would aid in formulating specific requirements concerning the design of control boosters in general. Results of the theoretical analysis and the bench tests indicate that the subject booster is representative of types which show promise of satisfactory performance. The bench tests showed that the following desirable features were inherent in this booster system: (1) No lost motion or play in any part of the system; (2) no detectable lag between motion of the contra1 stick and control surface; and (3) Good agreement between control displacements and stick-force variations with no hysteresis in the stick-force characteristics. The final design configuration of this booster system showed no tendency to oscillate, overshoot, or have other undesirable transient characteristics common to boosters.

KSC-06pd1492

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star tows a spent solid rocket booster toward Port Canaveral. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1497

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star heads up the Banana River to Cape Canaveral Air Force Station with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1491

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star tows a spent solid rocket booster back to Port Canaveral. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-08pd0258

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- The solid rocket booster retrieval ship Freedom Star tows one of the boosters retrieved after the launch of space shuttle Atlantis' STS-122 mission. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0260

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- The solid rocket booster retrieval ship Freedom Star tows one of the boosters, retrieved after the launch of space shuttle Atlantis' STS-122 mission, toward Port Canaveral. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0259

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- Spectators watch as the solid rocket booster retrieval ship Freedom Star tows one of the boosters, retrieved after the launch of space shuttle Atlantis' STS-122 mission, toward Port Canaveral. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd3735

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the straddle crane lowers a spent solid rocket booster onto a transporter. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The booster is from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd3738

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At Hangar AF at Cape Canaveral Air Force Station in Florida, two spent solid rocket boosters move into the washing bay for a cleaning and rinsing. The boosters are from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd0739

NASA Image and Video Library

2008-03-12

KENNEDY SPACE CENTER, FLA. -- The Freedom Star, one of NASA's solid rocket booster retrieval ships, tows a solid rocket booster alongside, heading for Hangar AF at Cape Canaveral Air Force Station. Barely visible in the background at right is the Vehicle Assembly Building at NASA's Kennedy Space Center. The booster is from space shuttle Endeavour, which launched the STS-123 mission on March 11. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters, which they tow back to port. After transfer to a position alongside the ship, the booster will be towed to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd0261

NASA Image and Video Library

2008-02-10

KENNEDY SPACE CENTER, FLA. -- The solid rocket booster retrieval ship Freedom Star tows toward Port Canaveral one of the boosters, retrieved after the launch of space shuttle Atlantis' STS-122 mission, toward Port Canaveral. The space shuttle's solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship's tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

Randomized, Open-Label Study of the Impact of Age on Booster Responses to the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine in Children in India

PubMed Central

Chatterjee, Sukanta; Chhatwal, Jugesh; Simon, Anna; Ravula, Sudheer; Francois, Nancy; Mehta, Shailesh; Strezova, Ana; Borys, Dorota

2014-01-01

In this phase III, open-label, multicenter, and descriptive study in India, children primed with 3 doses (at ages 6, 10, and 14 weeks) of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) were randomized (1:1) to receive a booster dose at 9 to 12 (early booster) or 15 to 18 months old (late booster) in order to evaluate impact of age at booster. We also evaluated a 2-dose catch-up vaccination plus an experimental booster dose in unprimed children age 12 to 18 months. The early booster, late booster, and catch-up vaccinations were administered to 74, 95, and 87 children, respectively; 66, 71, and 81 children, respectively, were included in the immunogenicity according-to-protocol cohort. One month postbooster, for each PHiD-CV serotype, ≥95.2% (early booster) and ≥93.8% (late booster) of the children had antibody concentrations of ≥0.2 μg/ml; ≥96.7% and ≥93.0%, respectively, had opsonophagocytic activity (OPA) titers of ≥8. The postbooster antibody geometric mean concentrations (GMCs) were in similar ranges for early and late boosters; the OPA titers appeared to be lower for most PHiD-CV serotypes (except 6B and 19F) after the early booster. After dose 2 and postbooster, for each PHiD-CV serotype, ≥88.6% and ≥96.3%, respectively, of the catch-up immunogenicity according-to-protocol cohort had antibody concentrations of ≥0.2 μg/ml; ≥71.4% and ≥90.6%, respectively, had OPA titers of ≥8. At least 1 serious adverse event was reported by 2 children in the early booster (skin infection and gastroenteritis) and 1 child in the catch-up group (febrile convulsion and urinary tract infection); all were resolved, and none were considered by the investigators to be vaccine related. PHiD-CV induced robust immune responses regardless of age at booster. Booster vaccination following 2 catch-up doses induced robust immune responses indicative of effective priming and immunological memory. (These studies have been registered at www.clinicaltrials.gov under registration no. NCT01030822 and NCT00814710; a protocol summary is available at www.gsk-clinicalstudyregister.com [study ID 112909]). PMID:25008901

NASA's Space Launch System Advanced Booster Development

NASA Technical Reports Server (NTRS)

Robinson, Kimberly F.; Crumbly, Christopher M.; May, Todd A.

2014-01-01

The National Aeronautics and Space Administration's (NASA's) Space Launch System (SLS) Program, managed at the Marshall Space Flight Center, is making progress toward delivering a new capability for human space flight and scientific missions beyond Earth orbit. NASA is executing this development within flat budgetary guidelines by using existing engines assets and heritage technology to ready an initial 70 metric ton (t) lift capability for launch in 2017, and then employing a block upgrade approach to evolve a 130-t capability after 2021. A key component of the SLS acquisition plan is a three-phased approach for the first-stage boosters. The first phase is to expedite the 70-t configuration by completing development of the Space Shuttle heritage 5-segment solid rocket boosters (SRBs) for the initial flights of SLS. Since no existing boosters can meet the performance requirements for the 130-t class SLS, the next phases of the strategy focus on the eventual development of advanced boosters with an expected thrust class potentially double the current 5-segment solid rocket booster capability of 3.88 million pounds of thrust each. The second phase in the booster acquisition plan is the Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) effort, for which contracts were awarded beginning in 2012 after a full and open competition, with a stated intent to reduce risks leading to an affordable advanced booster. NASA has awarded ABEDRR contracts to four industry teams, which are looking into new options for liquid-fuel booster engines, solid-fuel-motor propellants, and composite booster structures. Demonstrations and/or risk reduction efforts were required to be related to a proposed booster concept directly applicable to fielding an advanced booster. This paper will discuss the status of this acquisition strategy and its results toward readying both the 70 t and 130 t configurations of SLS. The third and final phase will be a full and open competition for Design, Development, Test, and Evaluation (DDT&E) of the advanced boosters. These new boosters will enable the flexible path approach to deep space exploration, opening up vast opportunities for human missions to near-Earth asteroids and Mars. This evolved capability will offer large volume for science missions and payloads, will be modular and flexible, and will be right-sized for mission requirements.

Effect of Casting Material on the Cast Pressure After Sequential Cast Splitting.

PubMed

Roberts, Aaron; Shaw, K Aaron; Boomsma, Shawn E; Cameron, Craig D

2017-01-01

Circumferential casting is a vital component of nonoperative fracture management. These casts are commonly valved to release pressure and decrease the risk of complications from swelling. However, little information exists regarding the effect of different casting supplies on the pressure within the cast. Seventy-five long-arm casts were performed on human volunteers, divided between 5 experimental groups with 15 casts in each groups. Testing groups consisted of 2 groups with a plaster short-arm cast overwrapped with fiberglass to a long arm with either cotton or synthetic cast padding. The 3 remaining groups included fiberglass long-arm casts with cotton, synthetic, or waterproof cast padding. A pediatric blood pressure cuff bladder was placed within the cast and inflated to 100 mm Hg. After inflation, the cast was sequentially released with pressure reading preformed after each stage. Order of release consisted of cast bivalve, cast padding release, and cotton stockinet release. After release, the cast was overwrapped with a loose elastic bandage. Difference in pressure readings were compared based upon the cast material. Pressures within the cast were found to decrease with sequential release of cast. The cast type had no effect of change in pressure. Post hoc testing demonstrated that the type of cast padding significantly affected the cast pressures with waterproof padding demonstrating the highest pressure readings at all time-points in the study, followed by synthetic padding. Cotton padding had the lowest pressure readings at all time-points. Type of cast padding significantly influences the amount of pressure within a long-arm cast, even after bivalving the cast and cutting the cast padding. Cotton cast padding allows for the greatest change in pressure. Cotton padding demonstrates the greatest change in pressure within a long-arm cast after undergoing bivalve. Synthetic and waterproof cast padding should not be used in the setting of an acute fracture to accommodate swelling.

47 CFR 22.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Operation of certificated signal boosters. 22.9... PUBLIC MOBILE SERVICES Scope and Authority § 22.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated under...

47 CFR 22.9 - Operation of certificated signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Operation of certificated signal boosters. 22.9... PUBLIC MOBILE SERVICES Scope and Authority § 22.9 Operation of certificated signal boosters. Individuals and non-individuals may operate certificated Consumer Signal Boosters on frequencies regulated under...

Closeup view of the Solid Rocket Booster Frustum and Nose ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the Solid Rocket Booster Frustum and Nose Cap assembly undergoing preparations and close-out procedures in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. The Nose Cap contains the Pilot and Drogue Chutes and the Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

KSC-2009-2142

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the solid rocket booster is lifted out of the water by the straddle crane. The booster, used during space shuttle Discovery's launch from NASA's Kennedy Space Center in Florida March 15 on mission STS-119, will be placed on a transporter. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-2009-2143

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the straddle crane lowers a solid rocket booster onto a transporter. The booster was used during space shuttle Discovery's launch from NASA's Kennedy Space Center in Florida March 15 on mission STS-119. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-2009-2140

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the frustum of a solid rocket booster is moved onto a transporter. The booster was used during space shuttle Discovery's launch on mission STS-119 from NASA's Kennedy Space Center in Florida March 15. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd3733

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, workers move the spent solid rocket booster to an area beneath the straddle crane that will lift it out of the water. The booster is from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The spent rocket was recovered by NASA's Solid Rocket Booster Retrieval Ship Freedom Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd3734

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the straddle crane lifts a spent solid rocket booster to allow saltwater contamination to be rinsed off. The booster is from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The spent rocket was recovered by NASA's Solid Rocket Booster Retrieval Ship Freedom Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

Orbital Payload Reductions Resulting from Booster and Trajectory Modifications for Recovery of a Large Rocket Booster

NASA Technical Reports Server (NTRS)

Levin, Alan D.; Hopkins, Edward J.

1961-01-01

An analysis was made to determine the reduction in payload for a 300 nautical mile orbit resulting from the addition of inert weight, representing recovery gear, to the first-stage booster of a three-stage rocket vehicle. The values of added inert weight investigated ranged from 0 to 18 percent of gross weight at lift off. The study also included the effects on the payload in orbit and the distance from the launch site at burnout and at impact caused by variation in the vertical rise time before the programmed tilt. The vertical rise times investigated ranged from 16-7 to 100 percent of booster burning time. For a vertical rise of 16.7 percent of booster burning time it was found that a 50-percent increase in the weight of the empty booster resulted in only a 10-percent reduction of the payload in orbit. For no added booster weight, increasing vertical rise time from 16-7 to 100 percent of booster burning time (so that the spent booster would impact in the launch area) reduced the payload by 37 percent. Increasing the vertical rise time from 16-7 to 50 percent of booster burning time resulted in about a 15-percent reduction in the impact distance, and for vertical rise times greater than 50-percent the impact distance decreased rapidly.

A modified Pegasus rocket drops steadily away after release from NASA's B-52B, before accelerating the X-43A over the Pacific Ocean on March 27, 2004

NASA Image and Video Library

2004-03-27

The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket drop away from NASA's B-52B launch aircraft over the Pacific Ocean on March 27, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif. Moments later the Pegasus booster ignited to accelerate the X-43A to its intended speed of Mach 7.

A modified Pegasus rocket drops away after release from NASA's B-52B before accelerating the X-43A over a Pacific Ocean test range on Nov. 16, 2004

NASA Image and Video Library

2004-11-16

The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket drop away from NASA's B-52B launch aircraft over the Pacific Ocean on November 16, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, California. Moments later the Pegasus booster ignited to accelerate the X-43A to its intended speed of Mach 10.

InSight Atlas V Booster Transport

NASA Image and Video Library

2018-03-02

A United Launch Alliance Atlas V booster departs building 7525 at Vandenberg Air Force Base in California on its way to Space Launch Complex 3. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

InSight Atlas V Booster Prep for Transport

NASA Image and Video Library

2018-03-01

A United Launch Alliance Atlas V booster is prepared for transport to Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

InSight Atlas V Booster Transport

NASA Image and Video Library

2018-03-02

A United Launch Alliance Atlas V booster arrives at Space Launch Complex 3 at Vandenberg Air Force Base in California. The rocket will be positioned on the pad to launch NASA's Interior Exploration using Seismic Investigations, Geodesy and Heat Transport, or InSight, mission to land on Mars. InSight is the first mission to explore the Red Planet's deep interior. It will investigate processes that shaped the rocky planets of the inner solar system including Earth. Liftoff is scheduled for May 5, 2018.

Energy-Saving Melting and Revert Reduction Technology (E-SMARRT): Lost Foam Thin Wall - Feasibility of Producing Lost Foam Castings in Aluminum and Magnesium Based Alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fasoyinu, Yemi; Griffin, John A.

2014-03-31

With the increased emphasis on vehicle weight reduction, production of near-net shape components by lost foam casting will make significant inroad into the next-generation of engineering component designs. The lost foam casting process is a cost effective method for producing complex castings using an expandable polystyrene pattern and un-bonded sand. The use of un-bonded molding media in the lost foam process will impose less constraint on the solidifying casting, making hot tearing less prevalent. This is especially true in Al-Mg and Al-Cu alloy systems that are prone to hot tearing when poured in rigid molds partially due to their longmore » freezing range. Some of the unique advantages of using the lost foam casting process are closer dimensional tolerance, higher casting yield, and the elimination of sand cores and binders. Most of the aluminum alloys poured using the lost foam process are based on the Al-Si system. Very limited research work has been performed with Al-Mg and Al-Cu type alloys. With the increased emphasis on vehicle weight reduction, and given the high-strength-to-weight-ratio of magnesium, significant weight savings can be achieved by casting thin-wall (≤ 3 mm) engineering components from both aluminum- and magnesium-base alloys.« less

Culture in Psychiatric Epidemiology: Using Ethnography and Multiple Mediator Models to Assess the Relationship of Caste with Depression and Anxiety in Nepal

PubMed Central

Kohrt, Brandon A.; Speckman, Rebecca A.; Kunz, Richard D.; Baldwin, Jennifer L.; Upadhaya, Nawaraj; Acharya, Nanda Raj; Sharma, Vidya Dev; Nepal, Mahendra K.; Worthman, Carol M.

2013-01-01

Background The causes of ethnic and caste-based disparities in mental health are poorly understood. Aim To identify mediators underlying caste-based disparities in mental health in Nepal. Subjects and methods A mixed methods ethnographic and epidemiological study of 307 adults (Dalit/Nepali, n=75; high caste Brahman and Chhetri, n=232) assessed with Nepali versions of Beck Depression (BDI) and Anxiety (BAI) Inventories. Results One third (33.7%) of participants were classified as depressed: Dalit/Nepali 50.0%, high caste 28.4%. One quarter (27.7%) of participants were classified as anxious: Dalit/Nepali 50.7%, high caste 20.3%. Ethnographic research identified four potential mediators: stressful life events, owning few livestock, no household income, and lack of social support. The direct effect of caste was 1.08 (95% CI -1.10—3.27) on depression score and 4.76 (95% CI 2.33—7.19) on anxiety score. All four variables had significant indirect (mediation) effects on anxiety, and all but social support had significant indirect effects on depression. Conclusion Caste-based disparities in mental health in rural Nepal are statistically mediated by poverty, lack of social support, and stressful life events. Interventions should target these areas to alleviate the excess mental health burden born by Dalit/Nepali women and men. PMID:19381985

Culture in psychiatric epidemiology: using ethnography and multiple mediator models to assess the relationship of caste with depression and anxiety in Nepal.

PubMed

Kohrt, Brandon A; Speckman, Rebecca A; Kunz, Richard D; Baldwin, Jennifer L; Upadhaya, Nawaraj; Acharya, Nanda Raj; Sharma, Vidya Dev; Nepal, Mahendra K; Worthman, Carol M

2009-01-01

The causes of ethnic and caste-based disparities in mental health are poorly understood. The study aimed to identify mediators underlying caste-based disparities in mental health in Nepal. A mixed methods ethnographic and epidemiological study of 307 adults (Dalit/Nepali, n=75; high caste Brahman and Chhetri, n=232) was assessed with Nepali versions of Beck Depression (BDI) and Anxiety (BAI) Inventories. One-third (33.7%) of participants were classified as depressed: Dalit/Nepali 50.0%, high caste 28.4%. One quarter (27.7%) of participants were classified as anxious: Dalit/Nepali 50.7%, high caste 20.3%. Ethnographic research identified four potential mediators: Stressful life events, owning few livestock, no household income, and lack of social support. The direct effect of caste was 1.08 (95% CI -1.10-3.27) on depression score and 4.76 (95% CI 2.33-7.19) on anxiety score. All four variables had significant indirect (mediation) effects on anxiety, and all but social support had significant indirect effects on depression. Caste-based disparities in mental health in rural Nepal are statistically mediated by poverty, lack of social support, and stressful life events. Interventions should target these areas to alleviate the excess mental health burden born by Dalit/Nepali women and men.

47 CFR 73.810 - Third adjacent channel interference.

Code of Federal Regulations, 2014 CFR

2014-10-01

... reception of the input signal of any TV translator, TV booster, FM translator or FM booster station; or (iii... authorized and operating LPFM stations, FM translators and FM booster stations. Interference will be... power FM, FM translator or FM booster station to such affected station and to the Commission. (ii) A...

47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

47 CFR 22.527 - Signal boosters.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 2 2012-10-01 2012-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

47 CFR 74.1290 - FM translator and booster station information available on the Internet.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 4 2012-10-01 2012-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

47 CFR 22.527 - Signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

47 CFR 74.1290 - FM translator and booster station information available on the Internet.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 4 2014-10-01 2014-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

47 CFR 74.1290 - FM translator and booster station information available on the Internet.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 4 2013-10-01 2013-10-01 false FM translator and booster station information... DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1290 FM translator and booster station information available on the Internet. The Media Bureau's Audio Division...

47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

47 CFR 73.810 - Third adjacent channel interference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... reception of the input signal of any TV translator, TV booster, FM translator or FM booster station; or (iii... authorized and operating LPFM stations, FM translators and FM booster stations. Interference will be... power FM, FM translator or FM booster station to such affected station and to the Commission. (ii) A...

47 CFR 22.527 - Signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Signal boosters. 22.527 Section 22.527... Paging and Radiotelephone Service § 22.527 Signal boosters. Licensees may install and operate signal boosters on channels listed in § 22.531 only in accordance with the provisions of § 22.165 governing...

47 CFR 95.1311 - Repeater operations and signal boosters prohibited.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Repeater operations and signal boosters... § 95.1311 Repeater operations and signal boosters prohibited. MURS stations are prohibited from operating as a repeater station or as a signal booster. This prohibition includes store-and-forward packet...

47 CFR 74.780 - Broadcast regulations applicable to translators, low power, and booster stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., low power, and booster stations. 74.780 Section 74.780 Telecommunication FEDERAL COMMUNICATIONS... PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.780 Broadcast regulations applicable to translators, low power, and booster stations. The following rules are applicable to...

47 CFR 101.151 - Use of signal boosters.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2012-10-01 2012-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

47 CFR 101.151 - Use of signal boosters.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2013-10-01 2013-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

47 CFR 101.151 - Use of signal boosters.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2010-10-01 2010-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

47 CFR 101.151 - Use of signal boosters.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2014-10-01 2014-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

47 CFR 101.151 - Use of signal boosters.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., or portable station(s). The booster will fill in only weak signal areas and cannot extend the system... 47 Telecommunication 5 2011-10-01 2011-10-01 false Use of signal boosters. 101.151 Section 101.151... SERVICES Technical Standards § 101.151 Use of signal boosters. Private operational-fixed licensees...

76 FR 11680 - Digital Low Power Television, Television Translator, and Television Booster Stations and Digital...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-03

...] Digital Low Power Television, Television Translator, and Television Booster Stations and Digital Class A... Commission's Rules to Establish Rules for Digital Low Power, Television Translator, and Television Booster... Digital Low Power Television Translator, Television Booster Stations, and to Amend Rules for Digital Class...

Liquid Rocket Booster Study. Volume 2, Book 1

NASA Technical Reports Server (NTRS)

1989-01-01

The recommended Liquid Rocket Booster (LRB) concept is shown which uses a common main engine with the Advanced Launch System (ALS) which burns LO2 and LH2. The central rationale is based on the belief that the U.S. can only afford one big new rocket engine development in the 1990's. A LO2/LH2 engine in the half million pound thrust class could satisfy STS LRB, ALS, and Shuttle C (instead of SSMEs). Development costs and higher production rates can be shared by NASA and USAF. If the ALS program does not occur, the LO2/RP-1 propellants would produce slight lower costs for and STS LRB. When the planned Booster Engine portion of the Civil Space Transportation Initiatives has provided data on large pressure fed LO2/RP-1 engines, then the choice should be reevaluated.

Aerodynamic flight evaluation analysis and data base update

NASA Technical Reports Server (NTRS)

Boyle, W. W.; Miller, M. S.; Wilder, G. O.; Reheuser, R. D.; Sharp, R. S.; Bridges, G. I.

1989-01-01

Research was conducted to determine the feasibility of replacing the Solid Rocket Boosters on the existing Space Shuttle Launch Vehicle (SSLV) with Liquid Rocket Boosters (LRB). As a part of the LRB selection process, a series of wind tunnel tests were conducted along with aero studies to determine the effects of different LRB configurations on the SSLV. Final results were tabulated into increments and added to the existing SSLV data base. The research conducted in this study was taken from a series of wind tunnel tests conducted at Marshall's 14-inch Trisonic Wind Tunnel. The effects on the axial force (CAF), normal force (CNF), pitching moment (CMF), side force (CY), wing shear force (CSR), wing torque moment (CTR), and wing bending moment (CBR) coefficients were investigated for a number of candidate LRB configurations. The aero effects due to LRB protuberances, ET/LRB separation distance, and aft skirts were also gathered from the tests. Analysis was also conducted to investigate the base pressure and plume effects due to the new booster geometries. The test results found in Phases 1 and 2 of wind tunnel testing are discussed and compared. Preliminary LRB lateral/directional data results and trends are given. The protuberance and gap/skirt effects are discussed. The base pressure/plume effects study is discussed and results are given.

Magnetic field errors tolerances of Nuclotron booster

NASA Astrophysics Data System (ADS)

Butenko, Andrey; Kazinova, Olha; Kostromin, Sergey; Mikhaylov, Vladimir; Tuzikov, Alexey; Khodzhibagiyan, Hamlet

2018-04-01

Generation of magnetic field in units of booster synchrotron for the NICA project is one of the most important conditions for getting the required parameters and qualitative accelerator operation. Research of linear and nonlinear dynamics of ion beam 197Au31+ in the booster have carried out with MADX program. Analytical estimation of magnetic field errors tolerance and numerical computation of dynamic aperture of booster DFO-magnetic lattice are presented. Closed orbit distortion with random errors of magnetic fields and errors in layout of booster units was evaluated.

Space shuttle phase B extension, volume 2

NASA Technical Reports Server (NTRS)

1971-01-01

Space shuttle systems are defined using a low technology orbiter combined with either an F-1 flyback booster or a pressure-fed booster. The mission and system requirements are given, and orbiter and booster configuration concepts are evaluated. Systems analyses and trades are discussed for LO2-RP propellent, F-1 engine main propulsion system, winged flyback recovery booster and for the pressure-fed, ocean recoverable, refurbishable booster system. Trade studies are also made for aluminum versus titanium orbiter and for crew location and compartment size.

Caste development and reproduction: a genome-wide analysis of hallmarks of insect eusociality

PubMed Central

Cristino, A S; Nunes, F M F; Lobo, C H; Bitondi, M M G; Simões, Z L P; Da Fontoura Costa, L; Lattorff, H M G; Moritz, R F A; Evans, J D; Hartfelder, K

2006-01-01

The honey bee queen and worker castes are a model system for developmental plasticity. We used established expressed sequence tag information for a Gene Ontology based annotation of genes that are differentially expressed during caste development. Metabolic regulation emerged as a major theme, with a caste-specific difference in the expression of oxidoreductases vs. hydrolases. Motif searches in upstream regions revealed group-specific motifs, providing an entry point to cis-regulatory network studies on caste genes. For genes putatively involved in reproduction, meiosis-associated factors came out as highly conserved, whereas some determinants of embryonic axes either do not have clear orthologs (bag of marbles, gurken, torso), or appear to be lacking (trunk) in the bee genome. Our results are the outcome of a first genome-based initiative to provide an annotated framework for trends in gene regulation during female caste differentiation (representing developmental plasticity) and reproduction. PMID:17069641

Awareness Programs and Change in Taste-Based Caste Prejudice

PubMed Central

Banerjee, Ritwik; Datta Gupta, Nabanita

2015-01-01

Becker's theory of taste-based discrimination predicts that relative employment of the discriminated social group will improve if there is a decrease in the level of prejudice for the marginally discriminating employer. In this paper we experimentally test this prediction offered by Garry Becker in his seminal work on taste based discrimination, in the context of caste in India, with management students (potential employers in the near future) as subjects. First, we measure caste prejudice and show that awareness through a TV social program reduces implicit prejudice against the lower caste and the reduction is sustained over time. Second, we find that the treatment reduces the prejudice levels of those in the left tail of the prejudice distribution - the group which can potentially affect real outcomes as predicted by the theory. And finally, a larger share of the treatment group subjects exhibit favorable opinion about reservation in jobs for the lower caste. PMID:25902290

Cold Cracking During Direct-Chill Casting

NASA Astrophysics Data System (ADS)

Eskin, D. G.; Lalpoor, M.; Katgerman, L.

Cold cracking phenomenon is the least studied, yet very important defect occurring during direct chill casting. The spontaneous nature of this defect makes its systematic study almost impossible, and the computer simulation of the thermomechanical behavior of the ingot during its cooling after the end of solidification requires constitutive parameters of high-strength aluminum alloys in the as-cast condition, which are not readily available. In this paper we describe constitutive behavior of high strength 7xxx series aluminum alloys in the as-cast condition based on experimentally measured tensile properties at different strain rates and temperatures, plane strain fracture toughness at different temperatures, and thermal contraction. In addition, fracture and structure of the specimens and real cold-cracked billets are examined. As a result a fracture-mechanics-based criterion of cold cracking is suggested based on the critical crack length, and is validated upon pilot-scale billet casting.

Awareness programs and change in taste-based caste prejudice.

PubMed

Banerjee, Ritwik; Datta Gupta, Nabanita

2015-01-01

Becker's theory of taste-based discrimination predicts that relative employment of the discriminated social group will improve if there is a decrease in the level of prejudice for the marginally discriminating employer. In this paper we experimentally test this prediction offered by Garry Becker in his seminal work on taste based discrimination, in the context of caste in India, with management students (potential employers in the near future) as subjects. First, we measure caste prejudice and show that awareness through a TV social program reduces implicit prejudice against the lower caste and the reduction is sustained over time. Second, we find that the treatment reduces the prejudice levels of those in the left tail of the prejudice distribution--the group which can potentially affect real outcomes as predicted by the theory. And finally, a larger share of the treatment group subjects exhibit favorable opinion about reservation in jobs for the lower caste.

Hybrid propulsion technology program. Volume 1: Conceptional design package

NASA Technical Reports Server (NTRS)

Jensen, Gordon E.; Holzman, Allen L.; Leisch, Steven O.; Keilbach, Joseph; Parsley, Randy; Humphrey, John

1989-01-01

A concept design study was performed to configure two sizes of hybrid boosters; one which duplicates the advanced shuttle rocket motor vacuum thrust time curve and a smaller, quarter thrust level booster. Two sizes of hybrid boosters were configured for either pump-fed or pressure-fed oxygen feed systems. Performance analyses show improved payload capability relative to a solid propellant booster. Size optimization and fuel safety considerations resulted in a 4.57 m (180 inch) diameter large booster with an inert hydrocarbon fuel. The preferred diameter for the quarter thrust level booster is 2.53 m (96 inches). As part of the design study critical technology issues were identified and a technology acquisition and demonstration plan was formulated.

TiC-Fe-Based Composite Coating Prepared by Self-Propagating High-Temperature Synthesis

NASA Astrophysics Data System (ADS)

He, Shen; Fan, Xi'an; Chang, Qingming; Xiao, Lixiang

2017-06-01

TiC-Fe-based composite coatings were prepared in situ by self-propagating high-temperature synthesis combined with vacuum expendable pattern casting process. The band-like TiC phase embedded in a continuous Fe binder. There were no obvious defects and impurities at the interface between coatings and matrices. Fe presented consecutively in the coating zones and substrate zones without interruption and the microhardness in the cross-sectional area of the coating-matrix reduces continuously from the coating to the matrix area, indicating a good metallurgical bonding between the coatings and matrices. The effect of casting temperature on the microstructure and hardness of TiC-Fe-based composite coating was investigated in detail. The TiC particles formed at low casting temperature were nearly spherical in shape, and the size of TiC particles increased with increasing casting temperature due to more agglomeration. The hardness of the coatings increased first and then decreased with increasing casting temperature, and reached the highest value of 68 HRC when the casting temperature was 1773 K (1500 °C), which was twice more than that of the matrix.

Comparison of Amplitudes and Frequencies of Explosive vs. Hammer Seismic Sources for a 1-km Seismic Line in West Texas

NASA Astrophysics Data System (ADS)

Kaip, G.; Harder, S. H.; Karplus, M. S.; Vennemann, A.

2016-12-01

In May 2016, the National Seismic Source Facility (NSSF) located at the University of Texas at El Paso (UTEP) Department of Geological Sciences collected seismic data at the Indio Ranch located 30 km southwest of Van Horn, Texas. Both hammer on an aluminum plate and explosive sources were used. The project objective was to image subsurface structures at the ranch, owned by UTEP. Selecting the appropriate seismic source is important to reach project objectives. We compare seismic sources between explosions and hammer on plate, focusing on amplitude and frequency. The seismic line was 1 km long, trending WSW to ENE, with 200 4.5 Hz geophones at 5m spacing and shot locations at 10m spacing. Clay slurry was used in shot holes to increase shot coupling around booster. Trojan Spartan cast boosters (150g) were used in explosive sources in each shot hole (1 hole per station). The end of line shots had 5 shot holes instead of 1 (750g total). The hammer source utilized a 5.5 kg hammer and an aluminum plate. Five hammer blows were stacked at each location to improve signal-to-noise ratio. Explosive sources yield higher amplitude, but lower frequency content. The explosions exhibit a higher signal-to-noise ratio, allowing us to recognize seismic energy deeper and farther from the source. Hammer sources yield higher frequencies, allowing better resolution at shallower depths but have a lower signal-to-noise ratio and lower amplitudes, even with source stacking. We analyze the details of the shot spectra from the different types of sources. A combination of source types can improve data resolution and amplitude, thereby improving imaging potential. However, cost, logistics, and complexities also have a large influence on source selection.

Performance evaluation of DAAF as a booster material using the onionskin test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morris, John S; Francois, Elizabeth G; Hooks, Daniel E

Initiation of insensitive high explosive (IHE) formulations requires the use of a booster explosive in the initiation train. Booster material selection is crucial, as the initiation must reliably function across some spectrum of physical parameters. The interest in Diaminoazoxyfurazan (DAAF) for this application stems from the fact that it possesses many traits of an IHE but is shock sensitive enough to serve as an explosive booster. A hemispherical wave breakout test, termed the onionskin test, is one of the methods used to evaluate the performance of a booster material. The wave breakout time-position history at the surface of a hemisphericalmore » IHE charge is recorded and the relative uniformity of the breakout can be quantitatively compared between booster materials. A series of onionskin tests were performed to investigate breakout and propagation diaminoazoxyfurazan (DAAF) at low temperatures to evaluate ignition and detonation spreading in comparison to other explosives commonly used in booster applications. Some wave perturbation was observed with the DAAF booster in the onionskin tests presented. The results of these tests will be presented and discussed.« less

Designing High Performance Steel Castings Today: Proceedings of the Steel Founders Society of America, Technical and Operating Conference December 7-10, 2016Chicago, IL

DTIC Science & Technology

2016-12-10

will be 2 x failure (critical) depth. G. INSPECTION REQUIREMENTS Either the No- Bake sand or Investment process is selected based on which... Bake sand and the Investment Casting Handbook by the Investment Casting Institute has the tolerance values for investment castings. Typically there

Investigation of the McDonnell-Douglas orbiter and booster shuttle models in proximity at Mach numbers 2.0 to 6.0. Volume 7: Proximity data at Mach 4 and 6, interference free and launch vehicle data

NASA Technical Reports Server (NTRS)

Trimmer, L. L.; Love, D. A.; Decker, J. P.; Blackwell, K. L.; Strike, W. T.; Rampy, J. M.

1972-01-01

Aerodynamic data obtained from a space shuttle abort stage separation wind tunnel test are presented. The .00556 scale models of the orbiter and booster configuration were tested in close proximity using dual balances during the time period of April 21 to April 27 1971. Data were obtained for both booster and orbiter over an angle of attack range from -10 to 10 deg for zero degree sideslip angle. The models were tested at several relative incidence angles and separation distances and power conditions. Plug nozzles utilizing air were used to simulate booster and orbiter plumes at various altitudes along a nominal ascent trajectory. Powered conditions were 100, 50, 25 and 0 percent of full power for the orbiter and 100, 50 and 0 percent of full power for the booster. Pitch control effectiveness data were obtained for both booster and orbiter with power on and off. In addition, launch vehicle data with and without booster power were obtained utilizing a single balance in the booster model. Data were also obtained with the booster canard off in close proximity and for the launch configuration.

KSC-06pd1494

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At a dock in Port Canaveral, the SRB Retrieval Ship Liberty Star has successfully transferred its tow cargo, a spent solid rocket booster, to a starboard position for the balance of its journey to Cape Canaveral Air Force Station. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1498

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - With the Vehicle Assembly Building in the background, the SRB Retrieval Ship Liberty Star nears Cape Canaveral Air Force Station with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1500

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star closes in on the dock at Hangar AF, Cape Canaveral Air Force Station, with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1502

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star arrives at the dock at Hangar AF, Cape Canaveral Air Force Station, with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1499

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star closes in on the dock at Hangar AF, Cape Canaveral Air Force Station, with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1503

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At the dock at Hangar AF, Cape Canaveral Air Force Station, the SRB Retrieval Ship Liberty Star gets ready to transfer the spent solid rocket booster to a straddle crane that will lift it out of the water. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1493

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At a dock in Port Canaveral, the SRB Retrieval Ship Liberty Star transfers its tow cargo, a spent solid rocket booster, to a starboard position for the balance of its journey to Cape Canaveral Air Force Station. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1495

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star begins the rest of its journey to Cape Canaveral Air Force Station with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1501

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star closes in on the dock at Hangar AF, Cape Canaveral Air Force Station, with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1506

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At the dock at Hangar AF, Cape Canaveral Air Force Station, workers move the spent solid rocket booster underneath the straddle crane that will lift it out of the water. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1496

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - The SRB Retrieval Ship Liberty Star begins the rest of its journey to Cape Canaveral Air Force Station with a spent solid rocket booster alongside. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-08pd3737

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, two spent solid rocket boosters begin moving to the hangar for the safing process. They will be driven through the washing bay for a cleaning and rinsing. The boosters are from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd3730

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – NASA's Solid Rocket Booster Retrieval Ship Freedom Star tows along its side one of the spent booster rockets from the space shuttle Endeavour launch Nov. 14 on the STS-126 mission. The ship is returning the spent rocket to Hangar AF at Cape Canaveral Air Force Station in Florida. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

Cellular and humoral immune responses to a tetanus toxoid booster in perinatally HIV-1-infected children and adolescents receiving highly active antiretroviral therapy (HAART).

PubMed

Ching, Natascha; Deville, Jaime G; Nielsen, Karin A; Ank, Bonnie; Wei, Lian S; Sim, Myung Shin; Wolinsky, Steven M; Bryson, Yvonne J

2007-01-01

Human immunodeficiency virus type 1 (HIV-1) infected children treated with highly active antiretroviral therapy (HAART) may develop a significant reduction of plasma viremia associated with an increase in CD4+ T-cell counts. Functional capacity of this reconstituted immune system in response to recall antigens is important to maintain protective immunity to vaccine-preventable diseases. We therefore determined cellular and humoral immune responses to tetanus toxoid (TT) booster in perinatally HIV-1-infected children and adolescents receiving HAART. Immune responses were prospectively evaluated pre- and post-tetanus booster using lymphocyte proliferation assay (LPA) stimulation index (SI > or = 3.0) and tetanus antibody (TAb > or = 0.15) in 15 patients. The median interval from primary tetanus immunization series was 6 years (range 2-12 years). We compared patients by their virological response to HAART (complete responders, CR, n=7; incomplete responders, ICR, n=8). There were no significant differences in median age 12.6 years (CR: 12.9; ICR: 10.6) or median CD4 T-cell pre-booster (CR: 35%/819; ICR: 26%/429) between groups. Tetanus LPA responses were observed in one patient prior to booster and in seven patients post-booster. In contrast, 38% of patients had protective TAb pre-booster, but 92% developed protective TAb post-booster. All of the CR and 5/6 ICR patients developed protective TAb. HIV-1-infected children and adolescents had modest LPA responses to tetanus following booster, similar to HIV-1-infected adults. However, the majority of patients developed protective TAb levels after booster and maintained the response. Shorter intervals may need to be considered for TT immunization boosters in HIV-1-infected pediatric patients, as only 38% had protective TAb at baseline.

Five year follow-up after a first booster vaccination against tick-borne encephalitis following different primary vaccination schedules demonstrates long-term antibody persistence and safety.

PubMed

Beran, Jiří; Xie, Fang; Zent, Olaf

2014-07-23

Long-term vaccination programs are recommended for individuals living in regions endemic for tick-borne encephalitis (TBE). Current recommendations suggest a first booster vaccine be administered 3 years after a conventional regimen or 12-18 months after a rapid regimen. However, the research supporting subsequent booster intervals is limited. The aim of this study was thus to evaluate the long-term persistence of TBE antibodies in adults and adolescents after a first booster dose with Encepur(®). A total of 323 subjects aged 15 years and over, who had received one of four different primary TBE vaccination series in a parent study, participated in this follow-up Phase IV trial. Immunogenicity and safety were assessed for up to five years after a first booster dose, which was administered three years after completion of the primary series. One subset of subjects was excluded from the booster vaccination since they had already received their booster prior to enrollment. For comparison, immune responses were still recorded for these subjects on Day 0 and on an annual basis until Year 5, but safety information was not collected. Following a booster vaccination, high antibody titers were recorded in all groups throughout the study. Neutralization test (NT) titers of ≥ 10 were noted in at least 94% of subjects at every time point post-booster (on Day 21 and through Years 1-5). These results demonstrated that a first booster vaccination following any primary immunization schedule results in high and long-lasting (>5 years) immune responses. These data lend support to the current belief that subsequent TBE booster intervals could be extended from the current recommendation. NCT00387634. Copyright © 2014 Elsevier Ltd. All rights reserved.

Robust Humoral and Cellular Immune Responses to Pertussis in Adults After a First Acellular Booster Vaccination.

PubMed

van der Lee, Saskia; van Rooijen, Debbie M; de Zeeuw-Brouwer, Mary-Lène; Bogaard, Marjan J M; van Gageldonk, Pieter G M; Marinovic, Axel Bonacic; Sanders, Elisabeth A M; Berbers, Guy A M; Buisman, Anne-Marie

2018-01-01

To reduce the pertussis disease burden, nowadays several countries recommend acellular pertussis (aP) booster vaccinations for adults. We aimed to evaluate the immunogenicity of a first adult aP booster vaccination at childbearing age. In 2014, healthy adults aged 25-29 years ( n  = 105), vaccinated during infancy with four doses of whole-cell pertussis (wP) vaccine, received a Tdap (tetanus, diphtheria, and aP) booster vaccination. Blood samples were collected longitudinally pre-booster, 2 and 4 weeks, and 1 year and 2 years post-booster. Tdap vaccine antigen-specific antibody levels and memory B- and T-cell responses were determined at all time points. Antibody persistence was calculated using a bi-exponential decay model. Upon booster vaccination, the IgG levels specific to all Tdap vaccine antigens were significantly increased. After an initial rapid decline in the first year, PT-IgG antibody decay was limited (15%) in the second year post-booster. The duration of a median level of PT-IgG ≥20 IU/mL was estimated to be approximately 9 years. Vaccine antigen-specific memory B- and T-cell numbers increased and remained at high levels although a significant decline was observed after 4 weeks post-booster. However, Th1, Th2, and Th17 cytokine production remained above pre-booster levels for 2 years. The Tdap booster vaccination in wP-primed Dutch adults induced robust long-term humoral and cellular immune responses to pertussis antigens. Furthermore, PT-IgG levels are predicted to remain above the presumed protective cut-off for at least 9 years which might deserves further attention in evaluating the current recommendation to revaccinate women during every new pregnancy.

Modelling the effects of booster dose vaccination schedules and recommendations for public health immunization programs: the case of Haemophilus influenzae serotype b.

PubMed

Charania, Nadia A; Moghadas, Seyed M

2017-09-13

Haemophilus influenzae serotype b (Hib) has yet to be eliminated despite the implementation of routine infant immunization programs. There is no consensus regarding the number of primary vaccine doses and an optimal schedule for the booster dose. We sought to evaluate the effect of a booster dose after receiving the primary series on the long-term disease incidence. A stochastic model of Hib transmission dynamics was constructed to compare the long-term impact of a booster vaccination and different booster schedules after receiving the primary series on the incidence of carriage and symptomatic disease. We parameterized the model with available estimates for the efficacy of Hib conjugate vaccine and durations of both vaccine-induced and naturally acquired immunity. We found that administering a booster dose substantially reduced the population burden of Hib disease compared to the scenario of only receiving the primary series. Comparing the schedules, the incidence of carriage for a 2-year delay (on average) in booster vaccination was comparable or lower than that observed for the scenario of booster dose within 1 year after primary series. The temporal reduction of symptomatic disease was similar in the two booster schedules, suggesting no superiority of one schedule over the other in terms of reducing the incidence of symptomatic disease. The findings underscore the importance of a booster vaccination for continued decline of Hib incidence. When the primary series provides a high level of protection temporarily, delaying the booster dose (still within the average duration of protection conferred by the primary series) may be beneficial to maintain longer-term protection levels and decelerate the decline of herd immunity in the population.

The effectiveness of booster sessions in CBT treatment for child and adolescent mood and anxiety disorders.

PubMed

Gearing, Robin E; Schwalbe, Craig S J; Lee, RaeHyuck; Hoagwood, Kimberly E

2013-09-01

To investigate the effects of booster sessions in cognitive behavioral therapy (CBT) for children and adolescents with mood or anxiety disorders, whereas controlling for youth demographics (e.g., gender, age), primary diagnosis, and intervention characteristics (e.g., treatment modality, number of sessions). Electronic databases were searched for CBT interventions for youth with mood and anxiety disorders. Fifty-three (k = 53) studies investigating 1,937 youth met criteria for inclusion. Booster sessions were examined using two case-controlled effect sizes: pre-post and pre-follow-up (6 months) effect sizes and employing weighted least squares (WLSs) regressions. Meta-analyses found pre-post studies with booster sessions had a larger effect size r = .58 (k = 15; 95% CI = 0.52-0.65; P < .01) than those without booster sessions r = .45 (k = 38; 95% CI = 0.41-0.49; P < .001). In the WLS regression analyses, controlling for demographic factors, primary diagnosis, and intervention characteristics, studies with booster sessions showed larger pre-post effect sizes than those without booster sessions (B = 0.13, P < .10). Similarly, pre-follow-up studies with booster sessions showed a larger effect size r = .64 (k = 10; 95% CI = 0.57-0.70; P < .10) than those without booster sessions r = .48 (k = 20; 95% CI = 0.42-0.53; P < .01). Also, in the WLS regression analyses, pre-follow-up studies showed larger effect sizes than those without booster sessions (B = 0.08, P < .01) after accounting for all control variables. Result suggests that CBT interventions with booster sessions are more effective and the effect is more sustainable for youth managing mood or anxiety disorders than CBT interventions without booster sessions. © 2013 Wiley Periodicals, Inc.

Randomized, open-label study of the impact of age on booster responses to the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine in children in India.

PubMed

Lalwani, Sanjay; Chatterjee, Sukanta; Chhatwal, Jugesh; Simon, Anna; Ravula, Sudheer; Francois, Nancy; Mehta, Shailesh; Strezova, Ana; Borys, Dorota

2014-09-01

In this phase III, open-label, multicenter, and descriptive study in India, children primed with 3 doses (at ages 6, 10, and 14 weeks) of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) were randomized (1:1) to receive a booster dose at 9 to 12 (early booster) or 15 to 18 months old (late booster) in order to evaluate impact of age at booster. We also evaluated a 2-dose catch-up vaccination plus an experimental booster dose in unprimed children age 12 to 18 months. The early booster, late booster, and catch-up vaccinations were administered to 74, 95, and 87 children, respectively; 66, 71, and 81 children, respectively, were included in the immunogenicity according-to-protocol cohort. One month postbooster, for each PHiD-CV serotype, ≥95.2% (early booster) and ≥93.8% (late booster) of the children had antibody concentrations of ≥0.2 μg/ml; ≥96.7% and ≥93.0%, respectively, had opsonophagocytic activity (OPA) titers of ≥8. The postbooster antibody geometric mean concentrations (GMCs) were in similar ranges for early and late boosters; the OPA titers appeared to be lower for most PHiD-CV serotypes (except 6B and 19F) after the early booster. After dose 2 and postbooster, for each PHiD-CV serotype, ≥88.6% and ≥96.3%, respectively, of the catch-up immunogenicity according-to-protocol cohort had antibody concentrations of ≥0.2 μg/ml; ≥71.4% and ≥90.6%, respectively, had OPA titers of ≥8. At least 1 serious adverse event was reported by 2 children in the early booster (skin infection and gastroenteritis) and 1 child in the catch-up group (febrile convulsion and urinary tract infection); all were resolved, and none were considered by the investigators to be vaccine related. PHiD-CV induced robust immune responses regardless of age at booster. Booster vaccination following 2 catch-up doses induced robust immune responses indicative of effective priming and immunological memory. (These studies have been registered at www.clinicaltrials.gov under registration no. NCT01030822 and NCT00814710; a protocol summary is available at www.gsk-clinicalstudyregister.com [study ID 112909]). Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Feasibility of producing cast-refractory metal-fiber superalloy composites

NASA Technical Reports Server (NTRS)

Mcintyre, R. D.

1973-01-01

A study was conducted to evaluate the feasibility of direct casting as a practical method for producing cast superalloy tungsten or columbium alloy fiber composites while retaining a high percentage of fiber strength. Fourteen nickel base, four cobalt, and three iron based matrices were surveyed for their degree of reaction with the metal fibers. Some stress-rupture results were obtained at temperatures of 760, 816, 871, and 1093 C for a few composite systems. The feasibility of producing acceptable composites of some cast nickel, cobalt, and iron matrix alloys with tungsten or columbium alloy fibers was demonstrated.

A Technology Pathway for Airbreathing, Combined-Cycle, Horizontal Space Launch Through SR-71 Based Trajectory Modeling

NASA Technical Reports Server (NTRS)

Kloesel, Kurt J.; Ratnayake, Nalin A.; Clark, Casie M.

2011-01-01

Access to space is in the early stages of commercialization. Private enterprises, mainly under direct or indirect subsidy by the government, have been making headway into the LEO launch systems infrastructure, of small-weight-class payloads of approximately 1000 lbs. These moderate gains have emboldened the launch industry and they are poised to move into the middle-weight class (roughly 5000 lbs). These commercially successful systems are based on relatively straightforward LOX-RP, two-stage, bi-propellant rocket technology developed by the government 40 years ago, accompanied by many technology improvements. In this paper we examine a known generic LOX-RP system with the focus on the booster stage (1st stage). The booster stage is then compared to modeled Rocket-Based and Turbine-Based Combined Cycle booster stages. The air-breathing propulsion stages are based on/or extrapolated from known performance parameters of ground tested RBCC (the Marquardt Ejector Ramjet) and TBCC (the SR-71/J-58 engine) data. Validated engine models using GECAT and SCCREAM are coupled with trajectory optimization and analysis in POST-II to explore viable launch scenarios using hypothetical aerospaceplane platform obeying the aerodynamic model of the SR-71. Finally, and assessment is made of the requisite research technology advances necessary for successful commercial and government adoption of combined-cycle engine systems for space access.

B-SAFER: A Web-Based Intervention for Drug Use and Intimate Partner Violence Demonstrates Feasibility and Acceptability Among Women in the Emergency Department

PubMed Central

Choo, Esther K.; Zlotnick, Caron; Strong, David R.; Squires, Daniel D.; Tapé, Chantal; Mello, Michael J.

2016-01-01

Background Addressing violence along with drug use change goals is critical for women with coexisting intimate partner violence (IPV) and substance use disorders (SUD). Methods This was an acceptability and feasibility study of BSAFER, a brief Web-based program and booster phone call addressing violence and drug use. A screening survey identified women with recent drug use and IPV in the emergency department (ED). Participants were randomized to BSAFER or a Web-based control program and booster call providing education about home fire safety. Program completion, usability, satisfaction and MI adherence were primary outcomes. Drug use and IPV outcomes were measured at baseline, one and three months. Results Forty women were enrolled (21 BSAFER, 19 control); 50% were non-white and mean age was 30 years. Most commonly used drugs were marijuana (88%) and cocaine (30%); 45% reported physical abuse and 33% severe combined physical and sexual abuse. Thirty-nine (98%) completed the Web program, 30 (75%) completed the booster, and 29 (73%) completed 3-month follow up. Mean System Usability Scale (SUS) for the BSAFER Web program was 84 (95% CI 78–89) of 100; mean Client Satisfaction Questionnaire (CSQ-8) was 28 (95% CI 26–29) of 32. MI adherence scores were high and similar for both the Web program and the booster. Both intervention and control groups had small mean decreases in weekly drug use days (0.7 days vs. 1.5 days); participants using drugs other than marijuana demonstrated greater average reductions in drug use than those using marijuana only. Conclusions An ED Web-based intervention for SUD and IPV in women demonstrated feasibility and acceptability. Future studies will examine efficacy of the BSAFER program and investigate whether specific subgroups of drug using women may be most responsive to ED-based Web interventions. PMID:26714233

Possibility of reconstruction of dental plaster cast from 3D digital study models

PubMed Central

2013-01-01

Objectives To compare traditional plaster casts, digital models and 3D printed copies of dental plaster casts based on various criteria. To determine whether 3D printed copies obtained using open source system RepRap can replace traditional plaster casts in dental practice. To compare and contrast the qualities of two possible 3D printing options – open source system RepRap and commercially available 3D printing. Design and settings A method comparison study on 10 dental plaster casts from the Orthodontic department, Department of Stomatology, 2nd medical Faulty, Charles University Prague, Czech Republic. Material and methods Each of 10 plaster casts were scanned by inEos Blue scanner and the printed on 3D printer RepRap [10 models] and ProJet HD3000 3D printer [1 model]. Linear measurements between selected points on the dental arches of upper and lower jaws on plaster casts and its 3D copy were recorded and statistically analyzed. Results 3D printed copies have many advantages over traditional plaster casts. The precision and accuracy of the RepRap 3D printed copies of plaster casts were confirmed based on the statistical analysis. Although the commercially available 3D printing enables to print more details than the RepRap system, it is expensive and for the purpose of clinical use can be replaced by the cheaper prints obtained from RepRap printed copies. Conclusions Scanning of the traditional plaster casts to obtain a digital model offers a pragmatic approach. The scans can subsequently be used as a template to print the plaster casts as required. Using 3D printers can replace traditional plaster casts primarily due to their accuracy and price. PMID:23721330

47 CFR 74.763 - Time of operation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Booster Stations § 74.763 Time of operation. (a) A low power TV, TV translator, or TV booster station is... or TV booster station is expected to provide service to the extent that such is within its control... necessary. (c) Failure of a low power TV, TV translator, or TV booster station to operate for a period of 30...

Competence in Lexical Boosters and Nativeness in Academic Writing of English: The Possible Relation

ERIC Educational Resources Information Center

Demir, Cüneyt

2017-01-01

Boosters are an important metadiscourse device for writers because it creates an emphatic impression in the reader. In addition, the competence of metadiscourse devices such as boosters is crucial in having native-fluency in academic writing. Therefore, this avoidance of using boosters may spawn foreignness in non-native writers' academic texts.…

47 CFR 74.763 - Time of operation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Booster Stations § 74.763 Time of operation. (a) A low power TV, TV translator, or TV booster station is... or TV booster station is expected to provide service to the extent that such is within its control... necessary. (c) Failure of a low power TV, TV translator, or TV booster station to operate for a period of 30...

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

47 CFR 74.763 - Time of operation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Booster Stations § 74.763 Time of operation. (a) A low power TV, TV translator, or TV booster station is... or TV booster station is expected to provide service to the extent that such is within its control... necessary. (c) Failure of a low power TV, TV translator, or TV booster station to operate for a period of 30...

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) Interference to the direct... continue to operate if an FM translator or FM booster station demonstrates that the LPFM station is causing...

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

47 CFR 74.763 - Time of operation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Booster Stations § 74.763 Time of operation. (a) A low power TV, TV translator, or TV booster station is... or TV booster station is expected to provide service to the extent that such is within its control... necessary. (c) Failure of a low power TV, TV translator, or TV booster station to operate for a period of 30...

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) Interference to the direct... authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster...

47 CFR 73.3572 - Processing of TV broadcast, Class A TV broadcast, low power TV, TV translators, and TV booster...

Code of Federal Regulations, 2010 CFR

2010-10-01

... broadcast, low power TV, TV translators, and TV booster applications. 73.3572 Section 73.3572..., low power TV, TV translators, and TV booster applications. (a) Applications for TV stations are..., TV translator, and TV booster stations authorized under part 74 of this chapter, a major change is...

47 CFR 73.827 - Interference to the input signals of FM translator or FM booster stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... translator or FM booster stations. 73.827 Section 73.827 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... Interference to the input signals of FM translator or FM booster stations. (a) An authorized LPFM station will not be permitted to continue to operate if an FM translator or FM booster station demonstrates that...

Evaluation of three variables affecting the casting of base metal alloys.

PubMed

Wight, T A; Grisius, R J; Gaugler, R W

1980-04-01

All the vented samples with sprue widths of 2 mm or more were defect free, whereas the corresponding unvented samples had extensive voids and porosity in all but one casting. All castings with a sprue width of 1 mm were defective regardless of whether or not vents were used. The thickness of the investment above the pattern had no effect on casting results.

Adolescent Abstinence and Unprotected Sex in CyberSenga, an Internet-Based HIV Prevention Program: Randomized Clinical Trial of Efficacy

PubMed Central

Ybarra, Michele L.; Bull, Sheana S.; Prescott, Tonya L.; Korchmaros, Josephine D.; Bangsberg, David R.; Kiwanuka, Julius P.

2013-01-01

Context Cost-effective, scalable programs are urgently needed in countries deeply affected by HIV. Methods This parallel-group RCT was conducted in four secondary schools in Mbarara, Uganda. Participants were 12 years and older, reported past-year computer or Internet use, and provided informed caregiver permission and youth assent. The intervention, CyberSenga, was a five-hour online healthy sexuality program. Half of the intervention group was further randomized to receive a booster at four-months post-intervention. The control arm received ‘treatment as usual’ (i.e., school-delivered sexuality programming). The main outcome measures were: 1) condom use and 2) abstinence in the past three months at six-months' post-intervention. Secondary outcomes were: 1) condom use and 2) abstinence at three-month's post-intervention; and 6-month outcomes by booster exposure. Analyses were intention to treat. Results All 416 eligible youth were invited to participate, 88% (n = 366) of whom enrolled. Participants were randomized to the intervention (n = 183) or control (n = 183) arm; 91 intervention participants were further randomized to the booster. No statistically significant results were noted among the main outcomes. Among the secondary outcomes: At three-month follow-up, trends suggested that intervention participants (81%) were more likely to be abstinent than control participants (74%; p = 0.08), and this was particularly true among youth who were abstinent at baseline (88% vs. 77%; p = 0.02). At six-month follow-up, those in the booster group (80%) reported higher rates of abstinence than youth in the intervention, no booster (57%) and control (55%) groups (p = 0.15); they also reported lower rates of unprotected sex (5%) compared to youth in the intervention, no booster (24%) and control (21%) groups (p = 0.21) among youth sexually active at baseline. Conclusions The CyberSenga program may affect HIV preventive behavior among abstinent youth in the short term and, with the booster, may also promote HIV preventive behavior among sexually active youth in the longer term. Trial Registration NCT00906178. PMID:23967069

High-Throughput Physiologically Based Toxicokinetic Models for ToxCast Chemicals

EPA Science Inventory

Physiologically based toxicokinetic (PBTK) models aid in predicting exposure doses needed to create tissue concentrations equivalent to those identified as bioactive by ToxCast. We have implemented four empirical and physiologically-based toxicokinetic (TK) models within a new R ...

Booster and higher antigen doses of inactivated influenza vaccine in HIV-infected patients.

PubMed

Johnston, Jessica A; Tincher, Lindsey B; Lowe, Denise K

2013-12-01

To review the literature regarding booster or higher doses of influenza antigen for increasing immunogenicity of inactivated influenza vaccine (IIV) in HIV-infected patients. MEDLINE (1966 to September 2013) was searched using the terms immunize, influenza, vaccine, and HIV or AIDS in combination with two-dose, booster-dose, increased antigen, or high-dose. One trial of booster dosing with standard doses (SDs) of IIV, trivalent (IIV3); 2 trials of booster dosing with intermediate doses (ID) of H1N1 IIV or IIV3; and 1 trial of high-dose (HD) IIV3 were identified. Trials administering 2-dose, booster-dose, or increased antigen of influenza vaccine to patients with HIV were reviewed. Because adjuvanted IIV is not available and IIV, quadrivalent was recently approved in the United States, studies evaluating these vaccines were excluded. HIV-infected individuals are at high risk for influenza-related complications; however, vaccination with SD IIV may not confer optimal protection. It has been postulated that booster or higher doses of influenza antigen may lead to increased immunogenicity. When ID and SD or ID with boosters were evaluated in HIV-infected patients, significant increases in surrogate markers for influenza protection were not achieved. However, HD IIV3 did result in significant increases in seroprotective antibody levels, though 'clinical' influenza was not evaluated. Currently, evidence is insufficient to reach conclusions about the efficacy of booster dosing, ID, or HD influenza vaccine in HIV-infected patients. Trials evaluating booster or higher-antigen doses of IIV for 'clinical' influenza are necessary before routinely recommending for HIV-infected patients.

Safety and immunogenicity of a booster dose of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults: A randomized phase 1 study.

PubMed

Marshall, Helen; Nissen, Michael; Richmond, Peter; Shakib, Sepehr; Jiang, Qin; Cooper, David; Rill, Denise; Baber, James; Eiden, Joseph; Gruber, William C; Jansen, Kathrin U; Anderson, Annaliesa S; Zito, Edward T; Girgenti, Douglas

2016-11-01

A 2-stage, phase 1, randomized, placebo-controlled study in healthy adults to assess immunogenicity and safety of a booster dose at three dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) containing recombinant clumping factor A (ClfA) and capsular polysaccharides 5 and 8 (CP5 and CP8) conjugated to a diphtheria toxoid. Six months after initial single vaccination, in Stage 2, SA3Ag recipients were randomized (1:1) to booster vaccination or placebo, while Stage 1 placebo recipients received placebo again. Pre- and post-vaccination blood samples were analyzed. In Stage 2 (n = 345), pre-booster CP5 and CP8 titers remained high with no increase post-booster. ClfA titers remained high after initial vaccination and increased post-booster, approaching the peak response to the initial dose. Post-booster local reactions were more frequent and of greater severity than reported after the initial vaccination, particularly for the high-dose level recipients. Post hoc analysis showed no dose-response pattern and no obvious association between diphtheria toxoid titers and local reactions after initial or booster vaccination. Immune responses after the initial vaccination persisted for the 12 months studied, with little additional response after the booster dose at 6 months. Post-booster injection site reactions were more frequent and more severe but self-limiting. CLINICALTRIALS. NCT01018641. Copyright © 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Pertussis Circulation Has Increased T-Cell Immunity during Childhood More than a Second Acellular Booster Vaccination in Dutch Children 9 Years of Age

PubMed Central

Schure, Rose-Minke; de Rond, Lia; Öztürk, Kemal; Hendrikx, Lotte; Sanders, Elisabeth; Berbers, Guy; Buisman, Anne-Marie

2012-01-01

Here we report the first evaluation of T-cell responses upon a second acellular pertussis booster vaccination in Dutch children at 9 years of age, 5 years after a preschool booster vaccination. Blood samples of children 9 years of age were studied longitudinally until 1 year after the second aP booster and compared with those after the first aP booster in children 4 and 6 years of age from a cross-sectional study. After stimulation with pertussis-vaccine antigens, Th1, Th2 and Th17 cytokine responses were measured and effector memory cells (CCR7-CD45RA-) were characterized by 8-colour FACS analysis. The second aP booster vaccination at pre-adolescent age in wP primed individuals did increase pertussis-specific Th1 and Th2 cytokine responses. Noticeably, almost all T-cell responses had increased with age and were already high before the booster vaccination at 9 years of age. The enhancement of T-cell immunity during the 5 year following the booster at 4 years of age is probably caused by natural boosting due to the a high circulation of pertussis. However, the incidence of pertussis is high in adolescents and adults who have only received the Dutch wP vaccine during infancy and no booster at 4 years of age. Therefore, an aP booster vaccination at adolescence or later in these populations might improve long-term immunity against pertussis and reduce the transmission to the vulnerable newborns. Trial Registration Controlled-Trials.com ISRCTN64117538 PMID:22860033

Insulation Reformulation Development

NASA Technical Reports Server (NTRS)

Chapman, Cynthia; Bray, Mark

2015-01-01

The current Space Launch System (SLS) internal solid rocket motor insulation, polybenzimidazole acrylonitrile butadiene rubber (PBI-NBR), is a new insulation that replaced asbestos-based insulations found in Space Shuttle heritage solid rocket boosters. PBI-NBR has some outstanding characteristics such as an excellent thermal erosion resistance, low thermal conductivity, and low density. PBI-NBR also has some significant challenges associated with its use: Air entrainment/entrapment during manufacture and lay-up/cure and low mechanical properties such as tensile strength, modulus, and fracture toughness. This technology development attempted to overcome these challenges by testing various reformulated versions of booster insulation. The results suggest the SLS program should continue to investigate material alternatives for potential block upgrades or use an entirely new, more advanced booster. The experimental design was composed of a logic path that performs iterative formulation and testing in order to maximize the effort. A lab mixing baseline was developed and documented for the Rubber Laboratory in Bldg. 4602/Room 1178.

IMM tracking of a theater ballistic missile during boost phase

NASA Astrophysics Data System (ADS)

Hutchins, Robert G.; San Jose, Anthony

1998-09-01

Since the SCUD launches in the Gulf War, theater ballistic missile (TBM) systems have become a growing concern for the US military. Detection, tracking and engagement during boost phase or shortly after booster cutoff are goals that grow in importance with the proliferation of weapons of mass destruction. This paper addresses the performance of tracking algorithms for TBMs during boost phase and across the transition to ballistic flight. Three families of tracking algorithms are examined: alpha-beta-gamma trackers, Kalman-based trackers, and the interactive multiple model (IMM) tracker. In addition, a variation on the IMM to include prior knowledge of a booster cutoff parameter is examined. Simulated data is used to compare algorithms. Also, the IMM tracker is run on an actual ballistic missile trajectory. Results indicate that IMM trackers show significant advantage in tracking through the model transition represented by booster cutoff.

KSC-06pd1505

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At the dock at Hangar AF, Cape Canaveral Air Force Station, workers move the spent solid rocket booster away from the SRB Retrieval Ship Liberty Star to an area beneath the straddle crane that will lift it out of the water. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-06pd1504

NASA Image and Video Library

2006-07-06

KENNEDY SPACE CENTER, FLA. - At the dock at Hangar AF, Cape Canaveral Air Force Station, workers move the spent solid rocket booster away from the SRB Retrieval Ship Liberty Star to an area beneath the straddle crane that will lift it out of the water. The booster is from Space Shuttle Discovery, which launched on July 4. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about 6 by 9 nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and ,after transfer to a position alongside the ship, to Hangar AF at Cape Canaveral Air Force Station. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/George Shelton

KSC-2009-2139

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, one of the solid rocket boosters used during space shuttle Discovery's launch March 15 on mission STS-119 is moved to an area beneath the straddle crane that will lift it out of the water. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-2009-2145

NASA Image and Video Library

2009-03-18

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, a solid rocket boosters used during space shuttle Discovery's launch from NASA's Kennedy Space Center in Florida March 15 on mission STS-119 waits in an area beneath the straddle crane that will lift it out of the water. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea after a launch. The spent rockets were recovered by NASA's Solid Rocket Booster Retrieval Ships Freedom Star and Liberty Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Jack Pfaller

KSC-08pd3736

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, workers prepare to move the spent solid rocket booster to the hangar for the safing process. It will be driven through the washing bay for a cleaning and rinsing. The booster is from space shuttle Endeavour, which launched Nov. 14 on the STS-126 mission. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

KSC-08pd3732

NASA Image and Video Library

2008-11-19

CAPE CANAVERAL, Fla. – At the dock at Hangar AF at Cape Canaveral Air Force Station in Florida, the spent solid rocket booster from space shuttle Endeavour's launch Nov. 14 on mission STS-126 is moved to an area beneath the straddle crane that will lift it out of the water. The space shuttle’s solid rocket booster casings and associated flight hardware are recovered at sea. The spent rocket was recovered by NASA's Solid Rocket Booster Retrieval Ship Freedom Star. The boosters impact the Atlantic Ocean approximately seven minutes after liftoff. The splashdown area is a square of about six by nine nautical miles located about 140 nautical miles downrange from the launch pad. The retrieval ships are stationed approximately 8 to 10 nautical miles from the impact area at the time of splashdown. As soon as the boosters enter the water, the ships accelerate to a speed of 15 knots and quickly close on the boosters. The pilot chutes and main parachutes are the first items to be brought on board. With the chutes and frustum recovered, attention turns to the boosters. The ship’s tow line is connected and the booster is returned to the Port and, after transfer to a position alongside the ship, to Hangar AF. There, the expended boosters are disassembled, refurbished and reloaded with solid propellant for reuse. Photo credit: NASA/Kim Shiflett

[Safety and immunogenicity of a 7-valent pneumococcal conjugate vaccine (Prevenar) booster dose in healthy Chinese toddlers].

PubMed

Li, Rong-cheng; Li, Feng-xiang; Li, Yan-ping

2009-06-01

To evaluate the safety and immunogenicity of the booster dose of 7 valent pneumococcal conjugate vaccine (PCV7) to the healthy Chinese toddlers who had received 3 primary doses. Four hundred and eighty-eight Chinese toddlers received a booster dose of PCV7 at age of 12-15 months following a primary series of the vaccine given at ages 3, 4, 5 months separately with Diphtheria Tetanus Acellular Pertussis Combined Vaccine (DTaP) in Group 1 or concurrently with DTaP in Group 2. Following the booster dose immunization, each subject was followed up for 30 days to observe the safety of the vaccine. Blood samples were taken from a subset of subjects prior and post 30 days the booster dose immunization to evaluate immunogenicity. A high proportion of subjects in Group 1 (89%) and Group 2 (91%) remained afebrile after the booster dose. Local reactions to the PCV7 booster dose were generally mild. For each serotype, the rise in GMC (post-/pre-vaccination) showed a statistically significant difference (P<0.0001) between both groups. PCV7 administered as a booster dose is generally safe, well tolerate, and immunogenic in healthy Chinese toddlers.

Hitching a ride on NASA's B-52 mother ship, the X-43A scramjet performed a captive carry evaluation flight from Edwards Air Force Base, California, January 26, 2004

NASA Image and Video Library

2004-01-26

Hitching a ride on the same B-52 mother ship that once launched X-15 research aircraft in the 1960s, NASA's X-43A scramjet and it's Pegasus booster rocket performed a captive carry evaluation flight from Edwards Air Force Base, California, January 26, 2004. The X-43 and it's booster remained mated to the B-52 throughout this mission, intended to check its readiness for launch. The hydrogen-fueled aircraft is autonomous and has a wingspan of approximately 5 feet, measures 12 feet long and weighs about 2,800 pounds.

NASA's Space Launch System Booster Passes Major Milestone on Journey to Mars (QM-2)

NASA Image and Video Library

2016-06-28

A booster for the most powerful rocket in the world, NASA’s Space Launch System (SLS), was fired up Tuesday, June 28 at 11:05 a.m. EDT for a second qualification ground test at Orbital ATK's test facilities in Promontory, Utah. This was the last full-scale test for the booster before SLS is ready in 2018 for the first uncrewed test flight with NASA’s Orion spacecraft, marking a key milestone on the agency’s Journey to Mars. The booster was tested at a cold motor conditioning target of 40 degrees Fahrenheit –the colder end of its accepted propellant temperature range. When ignited, temperatures inside the booster reached nearly 6,000 degrees. The two-minute, full-duration ground qualification test provided NASA with critical data on 82 qualification objectives that will support certification of the booster for flight. Engineers now will evaluate test data captured by more than 530 instrumentation channels on the booster.

Analysis of delayed TBE-vaccine booster after primary vaccination.

PubMed

Aerssens, Annelies; Cochez, Christel; Niedrig, Matthias; Heyman, Paul; Kühlmann-Rabens, Ilona; Soentjens, Patrick

2016-02-01

An open, uncontrolled single centre study was conducted in the Travel Clinic at the Military Hospital, Brussels. Eighty-eight subjects were recruited who had a primary series of tick-borne encephalitis (TBE) vaccine more than 5 years ago and who never received a booster dose afterwards. Response rate after booster vaccination was very high: 84 out of 88 subjects (95.5%) had neutralizing antibodies on plaque reduction neutralization test and all (100%) had IgG antibodies on ELISA, on Day 21-28 after booster vaccination. This study adds valuable information to the common situation of delayed booster interval. The results of our study indicate that in young healthy travellers (<50 years), one booster vaccination after a primary series of TBE vaccine in the past is sufficient to obtain protective antibodies, even if primary vaccination is much longer than the recommended booster interval of 5 years. © International Society of Travel Medicine, 2016. All rights reserved.For permissions, please e-mail: journals.permissions@oup.com.

Design of 3 GeV booster ring lattice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Etisken, O., E-mail: ozgur.etisken@cern.ch; Ciftci, A. K., E-mail: abbas.kenan.ciftci@cern.ch

2016-03-25

The aim of this study is to design of a 3 GeV booster ring for the 3 GeV storage ring. Electrons are needed to be accelerated to 3.0 GeV from 0.15 GeV energy. In this frame, we studied on two options for booster ring; a compact booster and the booster that shares the same tunnel with the storage ring. The lattice type has been chosen FODO for both options, lattice parameters are calculated, sextupole magnets are used to decrease dynamic aperture problem and dynamic aperture calculations are also made with considering of the necessary conditions. After designing and calculating ofmore » the parameters, these designs have been compared with each other. In addition to this comparison, these booster design parameters have been compared with some world centers design parameters and the reliability of the booster design is seen. Beam optics, OPA and Elegant simulation programs have been used in the study calculations.« less

A study of two statistical methods as applied to shuttle solid rocket booster expenditures

NASA Technical Reports Server (NTRS)

Perlmutter, M.; Huang, Y.; Graves, M.

1974-01-01

The state probability technique and the Monte Carlo technique are applied to finding shuttle solid rocket booster expenditure statistics. For a given attrition rate per launch, the probable number of boosters needed for a given mission of 440 launches is calculated. Several cases are considered, including the elimination of the booster after a maximum of 20 consecutive launches. Also considered is the case where the booster is composed of replaceable components with independent attrition rates. A simple cost analysis is carried out to indicate the number of boosters to build initially, depending on booster costs. Two statistical methods were applied in the analysis: (1) state probability method which consists of defining an appropriate state space for the outcome of the random trials, and (2) model simulation method or the Monte Carlo technique. It was found that the model simulation method was easier to formulate while the state probability method required less computing time and was more accurate.

The effect of casting conditions on the biaxial flexural strength of glass-ceramic materials.

PubMed

Johnson, A; Shareef, M Y; Walsh, J M; Hatton, P V; van Noort, R; Hill, R G

1998-11-01

To assess the effect of mould and glass casting temperatures on the biaxial flexural strength (BFS) of two different types of castable glass-ceramic, using existing laboratory equipment and techniques. Two castable glass-ceramic materials were evaluated. One glass (LG3) is based on SiO2-Al2O3-P2O5-CaO-CaF2, and is similar in composition to glasses used in the manufacture of glass-ionomer cements. The other glass (SG3) is based on SiO2-K2O-Na2O-CaO-CaF2, and is a canasite-based material. Both materials were used to produce discs of 12 mm diameter and 2 mm thickness using the same lost-wax casting process as used for metal castings. Mould temperatures of between 500 degrees C and 1000 degrees C and glass casting temperatures of between 1100 degrees C and 1450 degrees C were evaluated. The cast discs were cerammed and the biaxial flexural strength determined with a Lloyd 2000 R tester. A significant difference was found for the BFS in the range of mould temperatures evaluated, with the optimum investment mould temperature being 590 degrees C for LG3 and 610 degrees C for SG3 (p = 0.0002 and p = 0.019, respectively). No significant differences were seen between any of the glass casting temperatures evaluated. The mould temperature for castable glass-ceramic materials produced using the lost-wax casting process can have a significant effect on BFS. The optimum mould temperature may differ slightly depending on the type of material being used. The glass casting temperature of these materials does not appear to have a significant effect on BFS.

Aerodynamic characterisation and trajectory simulations for the Ariane-5 booster recovery system

NASA Astrophysics Data System (ADS)

Meiboom, F. P.

One of the most critical aspects of the early phases of the development of the Ariane-5 booster recovery system was the determination of the behavior of the booster during its atmospheric reentry, since this behavior determines the start conditions for the parachute system elements. A combination of wind-tunnel tests (subsonic and supersonic) and analytical methods was applied to define the aerodynamic characteristics of the booster. This aerodynamic characterization in combination with information of the ascent trajectory, atmospheric properties and booster mass and inertia were used as input for the 6-DOF trajectory simulations of the vehicle. Uncertainties in aerodynamic properties and deviations in atmospheric and booster properties were incorporated to define the range of initial conditions for the parachute system, utilizing stochastic (Monte-Carlo) methods.

SRB Processing Facilities Media Event

NASA Image and Video Library

2016-03-01

Members of the news media view forward booster segments (painted green) for NASA’s Space Launch System rocket boosters inside the Booster Fabrication Facility (BFF) at NASA’s Kennedy Space Center in Florida. Orbital ATK is a contractor for NASA’s Marshall Space Flight Center in Alabama, and operates the BFF to prepare aft booster segments and hardware for the SLS rocket boosters. The SLS rocket and Orion spacecraft will launch on Exploration Mission-1 in 2018. The Ground Systems Development and Operations Program is preparing the infrastructure to process and launch spacecraft for deep-space missions and the journey to Mars.

Closeup view of the Solid Rocket Booster Frustum and Nose ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the Solid Rocket Booster Frustum and Nose Cap assembly undergoing preparations and assembly procedures in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. The Nose Cap contains the Pilot and Drogue Chutes and the Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. In this view the assembly is rotated so that the four Separation Motors are in view and aligned with the approximate centerline of the image. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

A modified Pegasus rocket ignites moments after release from the B-52B, beginning the acceleration of the X-43A over the Pacific Ocean on Nov. 16, 2004

NASA Image and Video Library

2004-11-16

The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket accelerate after launch from NASA's B-52B launch aircraft over the Pacific Ocean on November 16, 2004. The mission originated from the NASA Dryden Flight Research Center at Edwards Air Force Base, California. Minutes later the X-43A separated from the Pegasus booster and accelerated to its intended speed of Mach 10.

NASA's B-52B launch aircraft takes off carrying the second X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on March 27, 2004

NASA Image and Video Library

2004-03-27

The second X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, Calif., on March 27, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 7.

NASA's B-52B launch aircraft takes off carrying the third X-43A hypersonic research vehicle attached to a modified Pegasus rocket, on November 16, 2004

NASA Image and Video Library

2004-11-16

The third X-43A hypersonic research aircraft and its modified Pegasus booster rocket left the runway, carried aloft by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was launched from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

NASA's B-52B launch aircraft cruises to a test range over the Pacific Ocean carrying the third X-43A vehicle attached to a Pegasus rocket on November 16, 2004

NASA Image and Video Library

2004-11-16

The third X-43A hypersonic research aircraft, attached to a modified Pegasus booster rocket, was taken to launch altitude by NASA's B-52B launch aircraft from the NASA Dryden Flight Research Center at Edwards Air Force Base, California, on November 16, 2004. About an hour later the Pegasus booster was released from the B-52 to accelerate the X-43A to its intended speed of Mach 10.

Tune Evaluation From Phased BPM Turn-By-Turn Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alexahin, Y.; Gianfelice-Wendt, E.; Marsh, W.

2010-05-18

In fast ramping synchrotrons like the Fermilab Booster the conventional methods of betatron tune evaluation from the turn-by-turn data may not work due to rapid changes of the tunes (sometimes in a course of a few dozens of turns) and a high level of noise. We propose a technique based on phasing of signals from a large number of BPMs which significantly increases the signal to noise ratio. Implementation of the method in the Fermilab Booster control system is described and some measurement results are presented.

Effect of casting geometry on mechanical properties of two nickel-base superalloys

NASA Technical Reports Server (NTRS)

Johnston, J. R.; Dreshfield, R. L.; Collins, H. E.

1976-01-01

An investigation was performed to determine mechanical properties of two rhenium-free modifications of alloy TRW, and to evaluate the suitability of the alloy for use in a small integrally cast turbine rotor. The two alloys were initially developed using stress rupture properties of specimens machined from solid gas turbine blades. Properties in this investigation were determined from cast to size bars and bars cut from 3.8 by 7.6 by 17.8 cm blocks. Specimens machined from blocks had inferior tensile strength and always had markedly poorer rupture lives than cast to size bars. At 1,000 C the cast to size bars had shorter rupture lives than those machined from blades. Alloy R generally had better properties than alloy S in the conditions evaluated. The results show the importance of casting geometry on mechanical properties of nickel base superalloys and suggest that the geometry of a component can be simulated when developing alloys for that component.

Preliminary Study into Shell Mold Casting of Nominal 60-Nitinol Alloy

DTIC Science & Technology

The present study was initiated to determine the feasibility of shell mold casting nominal 60- Nitinol into suitable EOD (Explosive Ordnance Disposal...surface finish and definition and property response of cast alloy. Based upon the results, 60- Nitinol appears quite suited to shell molding and a...concern lies in the casting porosity associated with the relatively large liquid-to-solid shrinkage of nominal 60- Nitinol .

Silicon-based Porous Ceramics via Freeze Casting of Preceramic Polymers

NASA Astrophysics Data System (ADS)

Naviroj, Maninpat

Freeze casting is a technique for processing porous materials that has drawn significant attention for its effectiveness in producing a variety of tailorable pore structures for ceramics, metals, and polymers. With freeze casting, pores are generated based on a solidification process where ice crystals act as a sacrificial template which can eventually be sublimated to create pores. While the majority of freeze-casting studies have been performed using conventional ceramic suspensions, this work explores an alternative processing route by freeze casting with preceramic polymer solutions. Significant differences exist between freeze casting of a particulate suspension and a polymeric solution. These changes affect the processing method, solidification behavior, and pore structure, thereby introducing new challenges and possibilities for the freeze-casting technique. The first part of this study explored the processing requirements involved with freeze casting of preceramic polymers, along with methods to control the resulting pore structure. Solvent choice, freezing front velocity, and polymer concentration were used as processing variables to manipulate the pore structures. A total of seven organic solvents were freeze cast with a polymethylsiloxane preceramic polymer to produce ceramics with isotropic, dendritic, prismatic, and lamellar pore morphologies. Changes in freezing front velocity and polymer concentration were shown to influence pore size, shape, and connectivity. Differences between suspension- and solution-based samples freeze cast under equivalent conditions were also investigated. Certain solidification microstructures were strongly affected by the presence of suspended particles, creating differences between pore structures generated from the same solvents. Additionally, processing of solution-based samples were found to be the more facile technique. Compressive strength and water permeability of dendritic and lamellar structures were analyzed to determine functional differences between the pore structures. Results show that dendritic structures were up to 30 times stronger, while lamellar structures provided higher permeability constants. A change in freezing front velocity was shown to significantly affect permeability but not compressive strength. Finally, improved pore alignment along the freezing direction was achieved by controlling the nucleation and growth of solvent crystals through the use of a grain-selection template. Dendritic samples freeze cast with a template showed substantial increase in pore alignment, as determined by image analysis and permeability tests, with the permeability constant increasing by up to 6-fold when compared to a control sample.

30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

30 CFR 57.22207 - Booster fans (I-A, II-A, III, and V-A mines).

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Booster fans (I-A, II-A, III, and V-A mines... NONMETAL MINES Safety Standards for Methane in Metal and Nonmetal Mines Ventilation § 57.22207 Booster fans (I-A, II-A, III, and V-A mines). (a) Booster fans shall be approved by MSHA under the applicable...

SIMULATIONS OF TRANSVERSE STACKING IN THE NSLS-II BOOSTER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fliller III, R.; Shaftan, T.

2011-03-28

The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The linac needs to deliver 15 nC in 80 - 150 bunches to the booster every minute to achieve current stability goals in the storage ring. This is a very stringent requirement that has not been demonstrated at an operating light source. We have developed a scheme to transversely stack two bunch trains in the NSLS-II booster in order to alleviate the charge requirements on the linac. This scheme has been outlined previously. In this paper we show particle tracking simulations of the tracking scheme.more » We show simulations of the booster ramp with a stacked beam for a variety of lattice errors and injected beam parameters. In all cases the performance of the proposed stacking method is sufficient to reduce the required charge from the linac. For this reason the injection system of the NSLS-II booster is being designed to include this feature. The NSLS-II injection system consists of a 200 MeV linac and a 3 GeV booster. The injectors must provide 7.5nC in bunch trains 80-150 bunches long every minute for top off operation of the storage ring. Top off then requires that the linac deliver 15nC of charge once losses in the injector chain are taken into consideration. This is a very stringent requirement that has not been demonstrated at an operating light source. For this reason we have developed a method to transversely stack two bunch trains in the booster while maintaining the charge transport efficiency. This stacking scheme has been discussed previously. In this paper we show the simulations of the booster ramp with a single bunch train in the booster. Then we give a brief overview of the stacking scheme. Following, we show the results of stacking two bunch trains in the booster with varying beam emittances and train separations. The behavior of the beam through the ramp is examined showing that it is possible to stack two bunch trains in the booster.« less

Influence of the casting processing route on the corrosion behavior of dental alloys.

PubMed

Galo, Rodrigo; Rocha, Luis Augusto; Faria, Adriana Claudia; Silveira, Renata Rodrigues; Ribeiro, Ricardo Faria; de Mattos, Maria da Gloria Chiarello

2014-12-01

Casting in the presence of oxygen may result in an improvement of the corrosion performance of most alloys. However, the effect of corrosion on the casting without oxygen for dental materials remains unknown. The aim of this study was to investigate the influence of the casting technique and atmosphere (argon or oxygen) on the corrosion behavior response of six different dental casting alloys. The corrosion behavior was evaluated by electrochemical measurements performed in artificial saliva for the different alloys cast in two different conditions: arc melting in argon and oxygen-gas flame centrifugal casting. A slight decrease in open-circuit potential for most alloys was observed during immersion, meaning that the corrosion tendency of the materials increases due to the contact with the solution. Exceptions were the Co-based alloys prepared by plasma, and the Co-Cr-Mo and Ni-Cr-4Ti alloys processed by oxidized flame, in which an increase in potential was observed. The amount of metallic ions released into the artificial saliva solution during immersion was similar for all specimens. Considering the pitting potential, a parameter of high importance when considering the fluctuating conditions of the oral environment, Co-based alloys show the best performance in comparison with the Ni-based alloys, independent of the processing route. Copyright © 2014 Elsevier B.V. All rights reserved.

Anti-pertussis antibody kinetics following DTaP-IPV booster vaccination in Norwegian children 7-8 years of age.

PubMed

Aase, Audun; Herstad, Tove Karin; Jørgensen, Silje Bakken; Leegaard, Truls Michael; Berbers, Guy; Steinbakk, Martin; Aaberge, Ingeborg

2014-10-14

At the age of 7-8 years a booster of diphtheria, tetanus, acellular pertussis and polio vaccine is recommended for children in Norway. In this cross-sectional study we have analysed the antibody levels against pertussis vaccine antigens in sera from 498 children aged 6-12 years. The purposes of this study were to investigate the duration of the booster response against the pertussis vaccine antigens pertussis toxin (PT) and filamentous haemagglutinin (FHA); to determine the presence of high levels of pertussis antibodies in absence of recent vaccination; and to analyse how booster immunisation may interfere with the serological pertussis diagnostics. Prior to the booster the IgG antibody levels against PT revealed a geometric mean of 7.3IU/ml. After the booster the geometric mean peak anti-PT IgG response reached to 45.6IU/ml, followed by a steady decline in antibody levels over the next few years. The IgG anti-FHA levels followed the anti-PT IgG profiles. Three years after the booster the geometric mean IgG levels were only slightly above pre-booster levels. Prior to the booster 44% of the sera contained ≤5IU/ml of anti-PT IgG compared to18% 3 years after and 30% 4 years after the booster. When recently vaccinated children were excluded, 6.2% of the children had anti-PT IgG levels above 50IU/ml which may indicate pertussis infection within the last 2 years. This study indicates that the currently used acellular pertussis vaccines induce moderate immune responses to the pertussis antigens and that the antibodies wane within few years after the booster. This lack of sustained immune response may partly be responsible for the increased number of pertussis cases observed in this age group during the last years. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Prevalence and predictors of booster seat use in Alberta, Canada.

PubMed

Golonka, Richard P; Dobbs, Bonnie M; Rowe, Brian H; Voaklander, Don

2016-08-15

To determine the prevalence of booster seat misuse in a Canadian province and identify determinants of non-use. A cross-sectional study using parking lot interviews and in-vehicle restraint inspections by trained staff was conducted at 67 randomly selected childcare centres across Alberta. Only booster-eligible children were included in this analysis. Odds ratios (OR) and 95% confidence intervals (CI) are reported using unadjusted and adjusted logistic regression. Overall, 23% of children were not in a booster seat, and in 31.8% of cases there was evidence of at least one misuse. Non-use increased significantly by age, from 22.2% for children 2 years of age to 47.8% for children 7 years of age (p = 0.02). Children who were at significantly increased risk of booster seat non-use were those in vehicles with drivers who could not recall the booster seat to seatbelt transition point (OR: 4.54; 95% CI: 2.05-10.06) or drivers who were under the age of 30 (OR: 3.54; 95% CI: 1.45-8.62). A front row seating position was also associated with significantly higher risk of nonuse (OR: 18.00; 95% CI: 2.78-116.56). Children in vehicles with grandparent drivers exhibited significantly decreased risk of booster seat non-use (OR: 0.21; 95% CI: 0.05-0.85). Messaging should continue to stress that the front seat is not a safe place for any child under the age of 9 as well as remind drivers of the booster seat to seatbelt transition point, with additional emphasis placed on appealing to parents under the age of 30. Future research should focus on the most effective means of communicating booster seat information to this group. Enacting mandatory booster seat legislation would be an important step to increase both awareness and proper use of booster seats in Alberta.

Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?

PubMed Central

Stoof, Susanne P.; Buisman, Anne-Marie; van Rooijen, Debbie M.; Boonacker, Rianne; van der Klis, Fiona R. M.; Sanders, Elisabeth A. M.; Berbers, Guy A. M.

2015-01-01

Background Antibody levels wane rapidly after Meningococcal serogroup C conjugate (MenCC) vaccination in young children, rendering the need for an adolescent booster dose. It is not clear whether circulating memory B cells are associated with persistence of MenC-specific antibody levels. Methods Measurement of MenC-specific IgG and IgA memory B cells and levels of serum and salivary MenC-specific IgG and IgA in healthy 10-, 12- and 15-year-olds prior to and one month and one year after a MenCC booster vaccination. All participants had received a primary MenCC vaccination nine years earlier. Results The number of circulating MenC-specific IgG memory B cells prior to booster was low and not predictive for MenC-specific IgG responses in serum or saliva post-booster, whereas the number of MenC-specific IgA memory B cells pre-booster positively correlated with MenC-specific IgA levels in saliva post-booster (R = 0.5, P<0.05). The booster induced a clear increase in the number of MenC-specific IgG and IgA memory B cells. The number of MenC-PS-specific IgG memory B cells at 1 month post-booster was highest in the 12-year-olds. The number of MenC-specific memory B cells at one month post-booster showed no correlation with the rate of MenC-specific antibody decay throughout the first year post-booster. Conclusions Circulating MenC-specific IgA memory B cells correlate with IgA responses in saliva, whereas circulating MenC-specific IgG memory B cells are not predictive for MenC-specific IgG responses in serum or saliva. Our results are suggestive for age-dependent differences in pre-existing memory against MenC. PMID:26458006

Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?

PubMed

Stoof, Susanne P; Buisman, Anne-Marie; van Rooijen, Debbie M; Boonacker, Rianne; van der Klis, Fiona R M; Sanders, Elisabeth A M; Berbers, Guy A M

2015-01-01

Antibody levels wane rapidly after Meningococcal serogroup C conjugate (MenCC) vaccination in young children, rendering the need for an adolescent booster dose. It is not clear whether circulating memory B cells are associated with persistence of MenC-specific antibody levels. Measurement of MenC-specific IgG and IgA memory B cells and levels of serum and salivary MenC-specific IgG and IgA in healthy 10-, 12- and 15-year-olds prior to and one month and one year after a MenCC booster vaccination. All participants had received a primary MenCC vaccination nine years earlier. The number of circulating MenC-specific IgG memory B cells prior to booster was low and not predictive for MenC-specific IgG responses in serum or saliva post-booster, whereas the number of MenC-specific IgA memory B cells pre-booster positively correlated with MenC-specific IgA levels in saliva post-booster (R = 0.5, P<0.05). The booster induced a clear increase in the number of MenC-specific IgG and IgA memory B cells. The number of MenC-PS-specific IgG memory B cells at 1 month post-booster was highest in the 12-year-olds. The number of MenC-specific memory B cells at one month post-booster showed no correlation with the rate of MenC-specific antibody decay throughout the first year post-booster. Circulating MenC-specific IgA memory B cells correlate with IgA responses in saliva, whereas circulating MenC-specific IgG memory B cells are not predictive for MenC-specific IgG responses in serum or saliva. Our results are suggestive for age-dependent differences in pre-existing memory against MenC.

47 CFR 74.1281 - Station records.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FM Broadcast Booster Stations § 74.1281 Station records. (a) The licensee of a station authorized... booster, except that the station records of a booster or translator licensed to the licensee of the...

47 CFR 74.1281 - Station records.

Code of Federal Regulations, 2012 CFR

2012-10-01

... FM Broadcast Booster Stations § 74.1281 Station records. (a) The licensee of a station authorized... booster, except that the station records of a booster or translator licensed to the licensee of the...

47 CFR 74.1281 - Station records.

Code of Federal Regulations, 2014 CFR

2014-10-01

... FM Broadcast Booster Stations § 74.1281 Station records. (a) The licensee of a station authorized... booster, except that the station records of a booster or translator licensed to the licensee of the...

47 CFR 74.1281 - Station records.

Code of Federal Regulations, 2013 CFR

2013-10-01

... FM Broadcast Booster Stations § 74.1281 Station records. (a) The licensee of a station authorized... booster, except that the station records of a booster or translator licensed to the licensee of the...

Processing of IN-718 Lattice Block Castings

NASA Technical Reports Server (NTRS)

Hebsur, Mohan G.

2002-01-01

Recently a low cost casting method known as lattice block casting has been developed by JAM Corporation, Wilmington, Massachusetts for engineering materials such as aluminum and stainless steels that has shown to provide very high stiffness and strength with only a fraction of density of the alloy. NASA Glenn Research Center has initiated research to investigate lattice block castings of high temperature Ni-base superalloys such as the model system Inconel-718 (IN-718) for lightweight nozzle applications. Although difficulties were encountered throughout the manufacturing process , a successful investment casting procedure was eventually developed. Wax formulation and pattern assembly, shell mold processing, and counter gravity casting techniques were developed. Ten IN-718 lattice block castings (each measuring 15-cm wide by 30-cm long by 1.2-cm thick) have been successfully produced by Hitchiner Gas Turbine Division, Milford, New Hampshire, using their patented counter gravity casting techniques. Details of the processing and resulting microstructures are discussed in this paper. Post casting processing and evaluation of system specific mechanical properties of these specimens are in progress.

Booster Seat Effectiveness Among Older Children: Evidence From Washington State.

PubMed

Anderson, D Mark; Carlson, Lindsay L; Rees, Daniel I

2017-08-01

The American Academy of Pediatrics has recommended that children as old as 12 years use a booster seat when riding in motor vehicles, yet little is known about booster seat effectiveness when used by older children. This study estimated the association between booster use and injuries among children aged 8-12 years who were involved in motor vehicle crashes. Researchers analyzed data on all motor vehicle crashes involving children aged 8-12 years reported to the Washington State Department of Transportation from 2002 to 2015. Data were collected in 2015 and analyzed in 2016. Children who were in a booster seat were compared with children restrained by a seat belt alone. Logistic regression was used to adjust for potential confounders. In unadjusted models, booster use was associated with a 29% reduction in the odds of experiencing any injury versus riding in a seat belt alone (OR=0.709, 95% CI=0.675, 0.745). In models adjusted for potential confounders, booster use was associated with a 19% reduction in the odds of any injury relative to riding in a seat belt alone (OR=0.814, 95% CI=0.749, 0.884). The risk of experiencing an incapacitating/fatal injury was not associated with booster use. Children aged 8-12 years involved in a motor vehicle crash are less likely to be injured if in a booster than if restrained by a seat belt alone. Because only 10% of U.S. children aged 8-12 years use booster seats, policies encouraging their use could lead to fewer injuries. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Shuttle Upgrade Using 5-Segment Booster (FSB)

NASA Technical Reports Server (NTRS)

Sauvageau, Donald R.; Huppi, Hal D.; McCool, A. A. (Technical Monitor)

2000-01-01

In support of NASA's continuing effort to improve the over-all safety and reliability of the Shuttle system- a 5-segment booster (FSB) has been identified as an approach to satisfy that overall objective. To assess the feasibility of a 5-segment booster approach, NASA issued a feasibility study contract to evaluate the potential of a 5-segment booster to improve the overall capability of the Shuttle system, especially evaluating the potential to increase the system reliability and safety. In order to effectively evaluate the feasibility of the 5-segment concept, a four-member contractor team was established under the direction of NASA Marshall Space Flight Center (MSFC). MSFC provided the overall program oversight and integration as well as program contractual management. The contractor team consisted of Thiokol, Boeing North American Huntington Beach (BNA), Lockheed Martin Michoud Space Systems (LMMSS) and United Space Alliance (USA) and their subcontractor bd Systems (Control Dynamics Division, Huntsville, AL). United Space Alliance included the former members of United Space Booster Incorporated (USBI) who managed the booster element portion of the current Shuttle solid rocket boosters. Thiokol was responsible for the overall integration and coordination of the contractor team across all of the booster elements. They were also responsible for all of the motor modification evaluations. Boeing North American (BNA) was responsible for all systems integration analyses, generation of loads and environments. and performance and abort mode capabilities. Lockheed Martin Michoud Space Systems (LMMSS) was responsible for evaluating the impacts of any changes to the booster on the external tank (ET), and evaluating any design changes on the external tank necessary to accommodate the FSB. USA. including the former USBI contingent. was responsible for evaluating any modifications to facilities at the launch site as well as any booster component design modifications.

ICAM Manufacturing Cost/Design Guide. Volume 3. Airframes. User’s Manual.

DTIC Science & Technology

1983-01-01

COST-DRIVER EFFECT 17 -413H Investment Cast 17 - 4PH Investment Cast 2 2 - U) *oo 0±0.01 ±0.02 ±0.03 0±0.01 ±0.02 ±0.03 356iA356 Aluminum 356/A356...B +20% CAST B +50% 17 - 4PH CRES DORC BASE INVESTMENT D OR C WITH 10% B +20% CAST D OR C WITH 50% B +30% B +60% NOTE: X-Ray Grade A Is an Impractical...per QQ-A-601 (sand castings) - 357 per MIL-A-21180 (sand castings) a Steel - 17 - 4PH CRES per AMS-5342, 5343, and 5344 or * company equivalent

Identification of Pertussis-Specific Effector Memory T Cells in Preschool Children

PubMed Central

Schure, Rose-Minke; Öztürk, Kemal; Berbers, Guy; Sanders, Elisabeth; van Twillert, Inonge; Carollo, Maria; Mascart, Françoise; Ausiello, Clara M.; van Els, Cecile A. C. M.; Smits, Kaat; Buisman, Anne-Marie

2015-01-01

Whooping cough remains a problem despite vaccination, and worldwide resurgence of pertussis is evident. Since cellular immunity plays a role in long-term protection against pertussis, we studied pertussis-specific T-cell responses. Around the time of the preschool acellular pertussis (aP) booster dose at 4 years of age, T-cell memory responses were compared in children who were primed during infancy with either a whole-cell pertussis (wP) or an aP vaccine. Peripheral blood mononuclear cells (PBMCs) were isolated and stimulated with pertussis vaccine antigens for 5 days. T cells were characterized by flow-based analysis of carboxyfluorescein succinimidyl ester (CFSE) dilution and CD4, CD3, CD45RA, CCR7, gamma interferon (IFN-γ), and tumor necrosis factor alpha (TNF-α) expression. Before the aP preschool booster vaccination, both the proliferated pertussis toxin (PT)-specific CD4+ and CD8+ T-cell fractions (CFSEdim) were higher in aP- than in wP-primed children. Post-booster vaccination, more pertussis-specific CD4+ effector memory cells (CD45RA− CCR7−) were induced in aP-primed children than in those primed with wP. The booster vaccination did not appear to significantly affect the T-cell memory subsets and functionality in aP-primed or wP-primed children. Although the percentages of Th1 cytokine-producing cells were alike in aP- and wP-primed children pre-booster vaccination, aP-primed children produced more Th1 cytokines due to higher numbers of proliferated pertussis-specific effector memory cells. At present, infant vaccinations with four aP vaccines in the first year of life result in pertussis-specific CD4+ and CD8+ effector memory T-cell responses that persist in children until 4 years of age and are higher than those in wP-primed children. The booster at 4 years of age is therefore questionable; this may be postponed to 6 years of age. PMID:25787136

Adaptive significance of the Indian caste system: an ecological perspective.

PubMed

Gadgil, M; Malhotra, K C

1983-01-01

Indian society is an agglomeration of several thousand endogamous groups or castes each with a restricted geographical range and a hereditarily determined mode of subsistence. These reproductively isolated castes may be compared to biological species, and the society thought of as a biological community with each caste having its specific ecological niche. In this paper we examine the ecological-niche relationships of castes which are directly dependent on natural resources. Evidence is presented to show that castes living together in the same region had so organized their pattern of resource use as to avoid excessive intercaste competition for limiting resources. Furthermore, territorial division of the total range of the caste regulated intra-caste competition. Hence, a particular plant or animal resource in a given locality was used almost exclusively by a given lineage within a caste generation after generation. This favoured the cultural evolution of traditions ensuring sustainable use of natural resources. This must have contributed significantly to the stability of Indian caste society over several thousand years. The collapse of the base of natural resources and increasing monetarization of the economy has, however, destroyed the earlier complementarity between the different castes and led to increasing conflicts between them in recent years.

Microstructure and mechanical properties of zirconium doped NiAl/Cr(Mo) hypoeutectic alloy prepared by injection casting

NASA Astrophysics Data System (ADS)

Sheng, L. Y.; Du, B. N.; Guo, J. T.

2017-01-01

NiAl based materials has been considered as most potential candidate of turbine blade, due to its excellent high-temperature properties. However the bad room-temperature properties handicap its application. In the present paper, the zirconium doped NiAl/Cr(Mo) hypoeutectic alloy is fabricated by conventional casting and injection casting technology to improve its room-temperature properties. The microstructure and compressive properties at different temperatures of the conventionally-cast and injection-cast were investigated. The results exhibit that the conventionally-cast alloy comprises coarse primary NiAl phase and eutectic cell, which is dotted with irregular Ni2AlZr Heusler phase. Compared with the conventionally-cast alloy, the injection-cast alloy possesses refined the primary NiAl, eutectic cell and eutectic lamella. In addition, the Ni2AlZr Heusler phase become smaller and distribute uniformly. Moreover, the injection casting decrease the area fraction of primary NiAl phase at the cell interior or cell boundaries. The compressive ductility and yield strength of the injection-cast alloy at room temperature increase by about 100% and 35% over those of conventionally-cast alloy, which should be ascribed to the microstructure optimization.

Analysis of Mold Friction in a Continuous Casting Using Wavelet Transform

NASA Astrophysics Data System (ADS)

Ma, Yong; Fang, Bohan; Ding, Qiqi; Wang, Fangyin

2018-04-01

Mold friction (MDF) is an important parameter reflecting the lubrication condition between the initial shell and the mold during continuous casting. In this article, based on practical MDF from the slab continuous casting driven by a mechanical vibration device, the characteristics of friction were analyzed by continuous wavelet transform (CWT) and discrete wavelet transform (DWT) in different casting conditions, such as normal casting, level fluctuation, and alarming of the temperature measurement system. The results show that the CWT of friction accurately captures the subtle changes in friction force, such as the periodic characteristic of MDF during normal casting and the disordered feature of MDF during level fluctuation. Most important, the results capture the occurrence of abnormal casting and display the friction frequency characteristics at this abnormal time. In addition, in this article, there are some abnormal casting conditions, and the friction signal is stable until there is a sudden large change when abnormal casting, such as split breakout and submerged entry nozzle breakage, occurs. The DWT has a good ability to capture the friction characteristics for such abnormal situations. In particular, the potential abnormal features of MDF were presented in advance, which provides strong support for identifying abnormal casting and even preventing abnormal casting.

Social class related inequalities in household health expenditure and economic burden: evidence from Kerala, south India

PubMed Central

2011-01-01

Background In the Indian context, a household's caste characteristics are most relevant for identifying its poverty and vulnerability status. Inadequate provision of public health care, the near-absence of health insurance and increasing dependence on the private health sector have impoverished the poor and the marginalised, especially the scheduled tribe population. This study examines caste-based inequalities in households' out-of-pocket health expenditure in the south Indian state of Kerala and provides evidence on the consequent financial burden inflicted upon households in different caste groups. Methods Using data from a 2003-2004 panel survey in Kottathara Panchayat that collected detailed information on health care consumption from 543 households, we analysed inequality in per capita out-of-pocket health expenditure across castes by considering households' health care needs and types of care utilised. We used multivariate regression to measure the caste-based inequality in health expenditure. To assess health expenditure burden, we analysed households incurring high health expenses and their sources of finance for meeting health expenses. Results The per capita health expenditures reported by four caste groups accord with their status in the caste hierarchy. This was confirmed by multivariate analysis after controlling for health care needs and influential confounders. Households with high health care needs are more disadvantaged in terms of spending on health care. Households with high health care needs are generally at higher risk of spending heavily on health care. Hospitalisation expenditure was found to have the most impoverishing impacts, especially on backward caste households. Conclusion Caste-based inequality in household health expenditure reflects unequal access to quality health care by different caste groups. Households with high health care needs and chronic health care needs are most affected by this inequality. Households in the most marginalised castes and with high health care need require protection against impoverishing health expenditures. Special emphasis must be given to funding hospitalisation, as this expenditure puts households most at risk in terms of mobilising monetary resources. However, designing protection instruments requires deeper understanding of how the uncovered financial burden of out-patient and hospitalisation expenditure creates negative consequences and of the relative magnitude of this burden on households. PMID:21214941

25. Detail of cast iron lamp post base with fluted ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. Detail of cast iron lamp post base with fluted wooded post at top, located at north end of bridge. VIEW NORTHEAST - Chelsea Street Bridge & Draw Tender's House, Spanning Chelsea River, Boston, Suffolk County, MA

U.S. Geological Survey's ShakeCast: A cloud-based future

USGS Publications Warehouse

Wald, David J.; Lin, Kuo-Wan; Turner, Loren; Bekiri, Nebi

2014-01-01

When an earthquake occurs, the U. S. Geological Survey (USGS) ShakeMap portrays the extent of potentially damaging shaking. In turn, the ShakeCast system, a freely-available, post-earthquake situational awareness application, automatically retrieves earthquake shaking data from ShakeMap, compares intensity measures against users’ facilities, sends notifications of potential damage to responsible parties, and generates facility damage assessment maps and other web-based products for emergency managers and responders. ShakeCast is particularly suitable for earthquake planning and response purposes by Departments of Transportation (DOTs), critical facility and lifeline utilities, large businesses, engineering and financial services, and loss and risk modelers. Recent important developments to the ShakeCast system and its user base are described. The newly-released Version 3 of the ShakeCast system encompasses advancements in seismology, earthquake engineering, and information technology applicable to the legacy ShakeCast installation (Version 2). In particular, this upgrade includes a full statistical fragility analysis framework for general assessment of structures as part of the near real-time system, direct access to additional earthquake-specific USGS products besides ShakeMap (PAGER, DYFI?, tectonic summary, etc.), significant improvements in the graphical user interface, including a console view for operations centers, and custom, user-defined hazard and loss modules. The release also introduces a new adaption option to port ShakeCast to the "cloud". Employing Amazon Web Services (AWS), users now have a low-cost alternative to local hosting, by fully offloading hardware, software, and communication obligations to the cloud. Other advantages of the "ShakeCast Cloud" strategy include (1) Reliability and robustness of offsite operations, (2) Scalability naturally accommodated, (3), Serviceability, problems reduced due to software and hardware uniformity, (4) Testability, freely available for new users, (5) Remotely supported, allowing expert-facilitated maintenance, (6) Adoptability, simplified with disk images, and (7) Security, built in at the very high level associated with AWS. The ShakeCast user base continues to expand and broaden. For example, Caltrans, the prototypical ShakeCast user and development supporter, has been providing guidance to other DOTs on the use of the National Bridge Inventory (NBI) database to implement fully-functional ShakeCast systems in their states. A long-term goal underway is to further "connect the DOTs" via a Transportation Pooled Fund (TPF) with participating state DOTs. We also review some of the many other users and uses of ShakeCast. Lastly, on the hazard input front, we detail related ShakeMap improvements and ongoing advancements in estimating the likelihood of shaking-induced secondary hazards at structures, facilities, bridges, and along roadways due to landslides and liquefaction, and implemented within the ShakeCast framework.

SRB Processing Facilities Media Event

NASA Image and Video Library

2016-03-01

The right-hand aft skirt, one part of the aft booster assembly for NASA’s Space Launch System solid rocket boosters, is in view in a processing cell inside the Booster Fabrication Facility (BFF) at NASA’s Kennedy Space Center in Florida. Orbital ATK is a contractor for NASA’s Marshall Space Flight Center in Alabama, and operates the BFF to prepare aft booster segments and hardware for the SLS rocket boosters. The SLS rocket and Orion spacecraft will launch on Exploration Mission-1 in 2018. The Ground Systems Development and Operations Program is preparing the infrastructure to process and launch spacecraft for deep-space missions and the journey to Mars.

Viscoelastic propellant effects on Space Shuttle Dynamics

NASA Technical Reports Server (NTRS)

Bugg, F.

1981-01-01

The program of solid propellant research performed in support of the space shuttle dynamics modeling effort is described. Stiffness, damping, and compressibility of the propellant and the effects of many variables on these properties are discussed. The relationship between the propellant and solid rocket booster dynamics during liftoff and boost flight conditions and the effects of booster vibration and propellant stiffness on free free solid rocket booster modes are described. Coupled modes of the shuttle system and the effect of propellant stiffness on the interfaces of the booster and the external tank are described. A finite shell model of the solid rocket booster was developed.

Launch Architecture Impact on Ascent Abort and Crew Survival

NASA Technical Reports Server (NTRS)

Mathias, Donovan L.; Lawrence, Scott L.

2006-01-01

A study was performed to assess the effect of booster configuration on the ascent abort process. A generic abort event sequence was created and booster related risk drivers were identified. Three model boosters were considered in light of the risk drivers: a solid rocket motor configuration, a side mount combination solid and liquid configuration, and a stacked liquid configuration. The primary risk drivers included explosive fireball, overpressure, and fragment effects and booster-crew module re-contact. Risk drivers that were not specifically booster dependent were not addressed. The solid rocket configuration had the most benign influence on an abort while the side mount architecture provided the most challenging abort environment.

Space shuttle phase B wind tunnel model and test information. Volume 1: Booster configuration

NASA Technical Reports Server (NTRS)

Glynn, J. L.; Poucher, D. E.

1988-01-01

Archived wind tunnel test data are available for flyback booster or other alternative recoverable configurations as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle. Considerable wind tunnel data was acquired by the competing contractors and the NASA Centers for an extensive variety of configurations with an array of wing and body planforms. All contractor and NASA wind tunnel test data acquired in the Phase B development have been compiled into a database and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration type. Basic components include the booster, the orbiter, and the launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbiter configuration types include straight and delta wings, lifting body, drop tanks and double delta wings. Launch configurations include booster and orbiter components in various stacked and tandem combinations. This is Volume 1 (Part 2) of the report -- Booster Configuration.

Space shuttle phase B wind tunnel model and test information. Volume 1: Booster configuration

NASA Technical Reports Server (NTRS)

Glynn, J. L.; Poucher, D. E.

1988-01-01

Archived wind tunnel test data are available for flyback booster or other alternative recoverable configurations as well as reusable orbiters studied during initial development (Phase B) of the Space Shuttle. Considerable wind tunnel data was acquired by the competing contractors and the NASA Centers for an extensive variety of configurations with an array of wing and body planforms. All contractor and NASA wind tunnel test data acquired in the Phase B development have been compiled into a database and are available for application to current winged flyback or recoverable booster aerodynamic studies. The Space Shuttle Phase B Wind Tunnel Database is structured by vehicle component and configuration type. Basic components include the booster, the orbiter and the launch vehicle. Booster configuration types include straight and delta wings, canard, cylindrical, retroglide and twin body. Orbiter configuration types include straight and delta wings, lifting body, drop tanks, and double delta wings. Launch configurations include booster and orbiter components in various stacked and tandem combinations. This is Volume 1 (Part 1) of the report -- Booster Configuration.

Did two booster doses for schoolchildren change the epidemiology of pertussis in Israel?

PubMed

Anis, Emilia; Moerman, Larisa; Ginsberg, Gary; Karakis, Isabella; Slater, Paul E; Warshavsky, Bruce; Gosinov, Ruslan; Grotto, Itamar; Marva, Esther

2018-05-28

Pertussis is the only vaccine-preventable disease that has re-emerged in Israel. In the last two decades, despite high primary immunization coverage, crude incidence increased over tenfold, with especially high morbidity among infants and adolescents and with 19 infant deaths. Two pertussis vaccine boosters were added, in 2005 for 7-year-olds and in 2011 for 13-year-olds. We reviewed age group incidence from 1999 to 2016, before and after the booster program introduction. We compared three groups of 13-15 year-olds with identical primary immunization but different booster immunization histories. Vaccine effectiveness was calculated before and after adjustment for specific incidence in those aged 65 and over. Two years after one booster, adjusted vaccine effectiveness was 74.5%. Two years after two boosters, adjusted vaccine effectiveness was 91.8%. However, crude morbidity rates were not reduced. The booster program has been effective only among recipient groups. The program will be continued. Israel is now encouraging pregnant women to be vaccinated against pertussis to improve protection of infants.

Perpendicular Biased Ferrite Tuned Cavities for the Fermilab Booster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romanov, Gennady; Awida, Mohamed; Khabiboulline, Timergali

2014-07-01

The aging Fermilab Booster RF system needs an upgrade to support future experimental program. The important feature of the upgrade is substantial enhancement of the requirements for the accelerating cavities. The new requirements include enlargement of the cavity beam pipe aperture, increase of the cavity voltage and increase in the repetition rate. The modification of the present traditional parallel biased ferrite cavities is rather challenging. An alternative to rebuilding the present Fermilab Booster RF cavities is to design and construct new perpendicular biased RF cavities, which potentially offer a number of advantages. An evaluation and a preliminary design of themore » perpendicular biased ferrite tuned cavities for the Fermilab Booster upgrade is described in the paper. Also it is desirable for better Booster performance to improve the capture of beam in the Booster during injection and at the start of the ramp. One possible way to do that is to flatten the bucket by introducing second harmonic cavities into the Booster. This paper also looks into the option of using perpendicularly biased ferrite tuners for the second harmonic cavities.« less

Counterrotatable booster compressor assembly for a gas turbine engine

NASA Technical Reports Server (NTRS)

Moniz, Thomas Ory (Inventor); Orlando, Robert Joseph (Inventor)

2004-01-01

A counterrotatable booster compressor assembly for a gas turbine engine having a counterrotatable fan section with a first fan blade row connected to a first drive shaft and a second fan blade row axially spaced from the first fan blade row and connected to a second drive shaft, the counterrotatable booster compressor assembly including a first compressor blade row connected to the first drive shaft and a second compressor blade row interdigitated with the first compressor blade row and connected to the second drive shaft. A portion of each fan blade of the second fan blade row extends through a flowpath of the counterrotatable booster compressor so as to function as a compressor blade in the second compressor blade row. The counterrotatable booster compressor further includes a first platform member integral with each fan blade of the second fan blade row at a first location so as to form an inner flowpath for the counterrotatable booster compressor and a second platform member integral with each fan blade of the second fan blade row at a second location so as to form an outer flowpath for the counterrotatable booster compressor.

Analysis of Rocket, Ram-Jet, and Turbojet Engines for Supersonic Propulsion of Long-Range Missles. II - Rocket Missile Performance

NASA Technical Reports Server (NTRS)

Huff, Vearl N.; Kerrebrock, Jack

1954-01-01

The theoretical performance of a two-stage ballistic rocket mis having a centerbody and two parallel boosters was investigated for J oxygen and ammonia-fluorine propellants. Both power-plant and missi parameters were optimized to give minimum cost on-the basis of the analysis for a range of 5500 nautical miles. After optimum values were found, each parameter was varied independently to determine its effect on performance of the missile. The missile using the ammonia-fluorine propellant weighs about one half as much as a missile using JP4-oxygen. Based on an expected unit cost of fluorine in quantity production, the ammonia-fluorine missile has a substantially lower relative cost than a JP4-oxygen missile. Optimum chamber pressures for both propellant systems and for both the centerbody and boosters were between 450 and 600 pounds per square inch. High design altitudes for the exhaust nozzle are desirable for both the centerbody and boosters. For the centerbody, the design altitude should be between 45,000 and 60,000 feet, with the value for ammonia-fluorine lower than that for JP4-oxygen. For the boosters, the design altitude should be 20,000 to 30,000 feet, with the value for the ammonia-fluorine. missile higher.

Large-eddy simulations of a solid-rocket booster jet

NASA Astrophysics Data System (ADS)

Paoli, Roberto; Poubeau, Adele; Cariolle, Daniel

2014-11-01

Emissions from solid-rocket boosters are responsible for a severe decrease in ozone concentration in the rocket plume during the first hours after a launch. The main source of ozone depletion is due to hydrogen chloride that is converted into chlorine in the high temperature regions of the jet (afterburning). The objective of this study is to evaluate the active chlorine concentration in the plume of a solid-rocket booster using large-eddy simulations. The gas is injected through the entire nozzle of the booster and a local time-stepping method based on coupling multi-instances of a fluid solver is used to extend the computational domain up to 600 nozzle exit diameters. The methodology is validated for a non-reactive case by analyzing the flow characteristics of supersonic co-flowing under expanded jets. Then, the chemistry of chlorine is studied offline using a complex chemistry solver and the LES data extracted from the mean trajectories of sample fluid particles. Finally, the online chemistry is analyzed by means of the multispecies version of the LES solver using a reduced chemistry scheme. The LES are able to capture the mixing of the exhaust with ambient air and the species concentrations, which is also useful to initialize atmospheric simulations on larger domains.

10. DETAIL OF CAST IRON COLUMN BASE ON FIRST FLOOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. DETAIL OF CAST IRON COLUMN BASE ON FIRST FLOOR STOREFRONT, SHOWING MANUFACTURER'S STAMP: IOWA IRON WOKS CO. DUBUQUE. VIEW TO SOUTHWEST. - Commercial & Industrial Buildings, Dubuque Seed Company Warehouse, 169-171 Iowa Street, Dubuque, Dubuque County, IA

Capillarity theory for the fly-casting mechanism

PubMed Central

Trizac, Emmanuel; Levy, Yaakov; Wolynes, Peter G.

2010-01-01

Biomolecular folding and function are often coupled. During molecular recognition events, one of the binding partners may transiently or partially unfold, allowing more rapid access to a binding site. We describe a simple model for this fly-casting mechanism based on the capillarity approximation and polymer chain statistics. The model shows that fly casting is most effective when the protein unfolding barrier is small and the part of the chain which extends toward the target is relatively rigid. These features are often seen in known examples of fly casting in protein–DNA binding. Simulations of protein–DNA binding based on well-funneled native-topology models with electrostatic forces confirm the trends of the analytical theory. PMID:20133683

Indigenous lunar construction materials

NASA Technical Reports Server (NTRS)

Rogers, Wayne; Sture, Stein

1991-01-01

The objectives are the following: to investigate the feasibility of the use of local lunar resources for construction of a lunar base structure; to develop a material processing method and integrate the method with design and construction of a pressurized habitation structure; to estimate specifications of the support equipment necessary for material processing and construction; and to provide parameters for systems models of lunar base constructions, supply, and operations. The topics are presented in viewgraph form and include the following: comparison of various lunar structures; guidelines for material processing methods; cast lunar regolith; examples of cast basalt components; cast regolith process; processing equipment; mechanical properties of cast basalt; material properties and structural design; and future work.

7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. VIEW OF BOOSTER STATION 3, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. VIEW OF BOOSTER STATION 1, FACING NORTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. VIEW OF BOOSTER STATION 4, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. VIEW OF BOOSTER STATION 4, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW OF BOOSTER STATION 1, FACING SOUTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW OF BOOSTER STATION 3, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. VIEW OF BOOSTER STATION 2, FACING NORTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST Nevada ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. VIEW OF BOOSTER STATION 2, FACING SOUTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

Space Shuttle Five-Segment Booster (Short Course)

NASA Technical Reports Server (NTRS)

Graves, Stanley R.; Rudolphi, Michael (Technical Monitor)

2002-01-01

NASA is considering upgrading the Space Shuttle by adding a fifth segment (FSB) to the current four-segment solid rocket booster. Course materials cover design and engineering issues related to the Reusable Solid Rocket Motor (RSRM) raised by the addition of a fifth segment to the rocket booster. Topics cover include: four segment vs. five segment booster, abort modes, FSB grain design, erosive burning, enhanced propellant burn rate, FSB erosive burning model development and hardware configuration.

Pressurization System Modeling for a Generic Bimese Two- Stage-to-Orbit Reusable Launch Vehicle

NASA Technical Reports Server (NTRS)

Mazurkivich, Pete; Chandler, Frank; Nguyen, Han

2005-01-01

A pressurization system model was developed for a generic bimese Two-Stage-to-orbit Reusable Launch Vehicle using a cross-feed system and operating with densified propellants. The model was based on the pressurization system model for a crossfeed subscale water test article and was validated with test data obtained from the test article. The model consists of the liquid oxygen and liquid hydrogen pressurization models, each made up of two submodels, Booster and Orbiter tank pressurization models. The tanks are controlled within a 0.2-psi band and pressurized on the ground with ambient helium and autogenously in flight with gaseous oxygen and gaseous hydrogen. A 15-psi pressure difference is maintained between the Booster and Orbiter tanks to ensure crossfeed check valve closure before Booster separation. The analysis uses an ascent trajectory generated for a generic bimese vehicle and a tank configuration based on the Space Shuttle External Tank. It determines the flow rates required to pressurize the tanks on the ground and in flight, and demonstrates the model's capability to analyze the pressurization system performance of a full-scale bimese vehicle with densified propellants.

KSC-2011-1836

NASA Image and Video Library

2011-02-26

CAPE CANAVERAL, Fla. -- Freedom Star, one of NASA's solid rocket booster retrieval ships, and its crew are preparing to recover the left spent booster from the Atlantic Ocean. The round objects on deck are large pumping machines that will be attached to the booster by a hose that will blow out debris and water and then pump in air so the booster can float horizontally on the water's surface for towing back to Port Canaveral in Florida. The shuttle’s two solid rocket booster casings and associated flight hardware are recovered in the Atlantic Ocean after every launch by Liberty Star and Freedom Star. The boosters impact the Atlantic about seven minutes after liftoff and the retrieval ships are stationed about 10 miles from the impact area at the time of splashdown. After the spent segments are processed, they will be transported to Utah, where they will be refurbished and stored, if needed. Photo credit: NASA/Ben Smegelsky

Long-term booster schedules with AS03A-adjuvanted heterologous H5N1 vaccines induces rapid and broad immune responses in Asian adults.

PubMed

Gillard, Paul; Chu, Daniel Wai Sing; Hwang, Shinn-Jang; Yang, Pan-Chyr; Thongcharoen, Prasert; Lim, Fong Seng; Dramé, Mamadou; Walravens, Karl; Roman, François

2014-03-15

The pandemic potential of avian influenza A/H5N1 should not be overlooked, and the continued development of vaccines against these highly pathogenic viruses is a public health priority. This open-label extension booster study followed a Phase III study of 1206 adults who had received two 3.75 μg doses of primary AS03A-adjuvanted or non-adjuvanted H5N1 split-virus vaccine (A/Vietnam/1194/2004; clade 1) (NCT00449670). The aim of the extension study was to evaluate different timings for heterologous AS03A-adjuvanted booster vaccination (A/Indonesia/5/2005; clade 2.1) given at Month 6, 12, or 36 post-primary vaccination. Immunogenicity was assessed 21 days after each booster vaccination and the persistence of immune responses against the primary vaccine strain (A/Vietnam) and the booster strain (A/Indonesia) was evaluated up to Month 48 post-primary vaccination. Reactogenicity and safety were also assessed. After booster vaccination given at Month 6, HI antibody responses to primary vaccine, and booster vaccine strains were markedly higher with one dose of AS03A-H5N1 booster vaccine in the AS03A-adjuvanted primary vaccine group compared with two doses of booster vaccine in the non-adjuvanted primary vaccine group. HI antibody responses were robust against the primary and booster vaccine strains 21 days after boosting at Month 12 or 36. At Month 48, in subjects boosted at Month 6, 12, or 36, HI antibody titers of ≥1:40 against the booster strain persisted in 39.2%, 61.2%, and 95.6% of subjects, respectively. Neutralizing antibody responses and cell-mediated immune responses also showed that AS03A-H5N1 heterologous booster vaccination elicited robust immune responses within 21 days of boosting at Month 6, 12, or 36 post-primary vaccination. The booster vaccine was well tolerated, and no safety concerns were raised. In Asian adults primed with two doses of AS03A-adjuvanted H5N1 pandemic influenza vaccine, strong cross-clade anamnestic antibody responses were observed after one dose of AS03A-H5N1 heterologous booster vaccine given at Month 6, 12, or 36 after priming, suggesting that AS03A-adjuvanted H5N1 vaccines may provide highly flexible prime-boost schedules. Although immunogenicity decreased with time, vaccinated populations could potentially be protected for up to three years after vaccination, which is likely to far exceed the peak of the a pandemic.

Long-term booster schedules with AS03A-adjuvanted heterologous H5N1 vaccines induces rapid and broad immune responses in Asian adults

PubMed Central

2014-01-01

Background The pandemic potential of avian influenza A/H5N1 should not be overlooked, and the continued development of vaccines against these highly pathogenic viruses is a public health priority. Methods This open-label extension booster study followed a Phase III study of 1206 adults who had received two 3.75 μg doses of primary AS03A-adjuvanted or non-adjuvanted H5N1 split-virus vaccine (A/Vietnam/1194/2004; clade 1) (NCT00449670). The aim of the extension study was to evaluate different timings for heterologous AS03A-adjuvanted booster vaccination (A/Indonesia/5/2005; clade 2.1) given at Month 6, 12, or 36 post-primary vaccination. Immunogenicity was assessed 21 days after each booster vaccination and the persistence of immune responses against the primary vaccine strain (A/Vietnam) and the booster strain (A/Indonesia) was evaluated up to Month 48 post-primary vaccination. Reactogenicity and safety were also assessed. Results After booster vaccination given at Month 6, HI antibody responses to primary vaccine, and booster vaccine strains were markedly higher with one dose of AS03A-H5N1 booster vaccine in the AS03A-adjuvanted primary vaccine group compared with two doses of booster vaccine in the non-adjuvanted primary vaccine group. HI antibody responses were robust against the primary and booster vaccine strains 21 days after boosting at Month 12 or 36. At Month 48, in subjects boosted at Month 6, 12, or 36, HI antibody titers of ≥1:40 against the booster strain persisted in 39.2%, 61.2%, and 95.6% of subjects, respectively. Neutralizing antibody responses and cell-mediated immune responses also showed that AS03A-H5N1 heterologous booster vaccination elicited robust immune responses within 21 days of boosting at Month 6, 12, or 36 post-primary vaccination. The booster vaccine was well tolerated, and no safety concerns were raised. Conclusions In Asian adults primed with two doses of AS03A-adjuvanted H5N1 pandemic influenza vaccine, strong cross-clade anamnestic antibody responses were observed after one dose of AS03A-H5N1 heterologous booster vaccine given at Month 6, 12, or 36 after priming, suggesting that AS03A-adjuvanted H5N1 vaccines may provide highly flexible prime–boost schedules. Although immunogenicity decreased with time, vaccinated populations could potentially be protected for up to three years after vaccination, which is likely to far exceed the peak of the a pandemic. PMID:24628789

Energy Consumption of Die Casting Operations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jerald Brevick; clark Mount-Campbell; Carroll Mobley

2004-03-15

Molten metal processing is inherently energy intensive and roughly 25% of the cost of die-cast products can be traced to some form of energy consumption [1]. The obvious major energy requirements are for melting and holding molten alloy in preparation for casting. The proper selection and maintenance of melting and holding equipment are clearly important factors in minimizing energy consumption in die-casting operations [2]. In addition to energy consumption, furnace selection also influences metal loss due to oxidation, metal quality, and maintenance requirements. Other important factors influencing energy consumption in a die-casting facility include geographic location, alloy(s) cast, starting formmore » of alloy (solid or liquid), overall process flow, casting yield, scrap rate, cycle times, number of shifts per day, days of operation per month, type and size of die-casting form of alloy (solid or liquid), overall process flow, casting yield, scrap rate, cycle times, number of shifts per day, days of operation per month, type and size of die-casting machine, related equipment (robots, trim presses), and downstream processing (machining, plating, assembly, etc.). Each of these factors also may influence the casting quality and productivity of a die-casting enterprise. In a die-casting enterprise, decisions regarding these issues are made frequently and are based on a large number of factors. Therefore, it is not surprising that energy consumption can vary significantly from one die-casting enterprise to the next, and within a single enterprise as function of time.« less

Development of the manufacture of billets based on high-strength aluminum alloys

NASA Astrophysics Data System (ADS)

Korostelev, V. F.; Denisov, M. S.; Bol'shakov, A. E.; Van Khieu, Chan

2017-09-01

When pressure is applied upon casting as a factor of external impact on melt, the problems related mainly to filling of molds are solved; however, some casting defects cannot be avoided. The experimental results demonstrate that complete compensation of shrinkage under pressure can be achieved by compressing of casting by 8-10% prior to beginning of solidification and by 2-3% during the transition of a metal from the liquid to the solid state. It is mentioned that the procedure based on compressing a liquid metal can be efficiently applied for manufacture of high-strength aluminum alloy castings. The selection of engineering parameters is substantiated. Examples of castings made of V95 alloy according to the developed procedure are given. In addition, the article discusses the problems related to designing of engineering and special-purpose equipment, software, and control automation.

Hot-tearing of multicomponent Al-Cu alloys based on casting load measurements in a constrained permanent mold

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sabau, Adrian S; Mirmiran, Seyed; Glaspie, Christopher

Hot-tearing is a major casting defect that is often difficult to characterize, especially for multicomponent Al alloys used for cylinder head castings. The susceptibility of multicomponent Al-Cu alloys to hot-tearing during permanent mold casting was investigated using a constrained permanent mold in which the load and displacement was measured. The experimental results for hot tearing susceptibility are compared with those obtained from a hot-tearing criterion based temperature range evaluated at fraction solids of 0.87 and 0.94. The Cu composition was varied from approximately 5 to 8 pct. (weight). Casting experiments were conducted without grain refining. The measured load during castingmore » can be used to indicate the severity of hot tearing. However, when small hot-tears are present, the load variation cannot be used to detect and assess hot-tearing susceptibility.« less

Preliminary study of oxide-dispersion-strengthened B-1900 prepared by mechanical alloys

NASA Technical Reports Server (NTRS)

Glasgow, T. K.; Quatinetz, M.

1975-01-01

An experimental oxide dispersion strengthened (ODS) alloy based on the B-1900 composition was produced by the mechanical alloying process. Without optimization of the processing for the alloy or the alloy for the processing, recrystallization of the extruded product to large elongated grains was achieved. Materials having grain length-width ratios of 3 and 5.5 were tested in tension and stress-rupture. The ODS B-1900 exhibited tensile strength similar to that of cast B-1900. Its stress-rupture life was lower than that of cast B-1900 at 760 C. At 1095 C the ODS B-1900 with the higher grain length-width ratio (5.5) had stress-rupture life superior to that of cast B-1900. It was concluded that, with optimization, oxide dispersion strengthening of B-1900 and other complex cast nickel-base alloys has potential for improving high temperature properties over those of the cast alloy counterparts.

A Statistics-Based Cracking Criterion of Resin-Bonded Silica Sand for Casting Process Simulation

NASA Astrophysics Data System (ADS)

Wang, Huimin; Lu, Yan; Ripplinger, Keith; Detwiler, Duane; Luo, Alan A.

2017-02-01

Cracking of sand molds/cores can result in many casting defects such as veining. A robust cracking criterion is needed in casting process simulation for predicting/controlling such defects. A cracking probability map, relating to fracture stress and effective volume, was proposed for resin-bonded silica sand based on Weibull statistics. Three-point bending test results of sand samples were used to generate the cracking map and set up a safety line for cracking criterion. Tensile test results confirmed the accuracy of the safety line for cracking prediction. A laboratory casting experiment was designed and carried out to predict cracking of a cup mold during aluminum casting. The stress-strain behavior and the effective volume of the cup molds were calculated using a finite element analysis code ProCAST®. Furthermore, an energy dispersive spectroscopy fractographic examination of the sand samples confirmed the binder cracking in resin-bonded silica sand.

Space shuttle: Experimental investigations for base drag reduction on a 0.015 scale model MSFS proposed space shuttle booster at Mach numbers from 0.40 to 1.10

NASA Technical Reports Server (NTRS)

Bradley, D.

1972-01-01

A 0.015-scale model of a modified version of the MDAC space shuttle booster was tested to obtain force, static stability, and control effectiveness data. The objective of this test was the reduction of cruise (M = 0.4) base drag by the use of base flaps, base vents, elevon deflection and base flow from a plenum mounted forward of the base heat shield. Transonic data were also obtained to determine the aerodynamic characteristics of the new base shape. Six component aerodynamic force and moment data were recorded over an angle of attack range from 4 deg to 20 deg at 0 deg sideslip and over a sideslip range from -6 deg to 6 deg at 0 deg, 6 deg and 15 deg angle of attack. Mach number varied from 0.4 to 1.10 at a constant R of 2 million per unit length.

A randomized trial evaluating a parent based intervention to reduce college drinking.

PubMed

Doumas, Diana M; Turrisi, Rob; Ray, Anne E; Esp, Susan M; Curtis-Schaeffer, Amy K

2013-07-01

This study evaluated the effectiveness of a parent based intervention (PBI) in reducing drinking among first year college students (N=443). Students were assigned to one of three conditions: PBI, PBI plus booster brochures (PBI-B), and an assessment only control group (CNT). At a 4-month post-intervention follow-up, results indicated students in the PBI-B group reported significantly less drinking to intoxication and peak drinking relative to the PBI group and CNT group. No significant differences were found between the PBI group and CNT group. Results provide further support for PBIs to reduce college student drinking and suggest that a booster brochure increases the effectiveness of PBIs. Copyright © 2013 Elsevier Inc. All rights reserved.

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-19

VANDENBERG AIR FORCE BASE, Calif. – The truck transporting the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, backs toward the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is positioned inside the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is towed to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, arrives at the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-19

VANDENBERG AIR FORCE BASE, Calif. – The truck transporting the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, arrives outside the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

Recommendations for Safe Separation Distances from the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB) Using a Heat-Flux-Based Analytical Approach (Abridged)

NASA Technical Reports Server (NTRS)

Cragg, Clinton H.; Bowman, Howard; Wilson, John E.

2011-01-01

The NASA Engineering and Safety Center (NESC) was requested to provide computational modeling to support the establishment of a safe separation distance surrounding the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB). The two major objectives of the study were 1) establish a methodology based on thermal flux to determine safe separation distances from the Kennedy Space Center's (KSC's) Vehicle Assembly Building (VAB) with large numbers of solid propellant boosters containing hazard division 1.3 classification propellants, in case of inadvertent ignition; and 2) apply this methodology to the consideration of housing eight 5-segment solid propellant boosters in the VAB. The results of the study are contained in this report.

Estimation of Heat Transfer Coefficient in Squeeze Casting of Magnesium Alloy AM60 by Experimental Polynomial Extrapolation Method

NASA Astrophysics Data System (ADS)

Sun, Zhizhong; Niu, Xiaoping; Hu, Henry

In this work, a different wall-thickness 5-step (with thicknesses as 3, 5, 8, 12, 20 mm) casting mold was designed, and squeeze casting of magnesium alloy AM60 was performed in a hydraulic press. The casting-die interfacial heat transfer coefficients (IHTC) in 5-step casting were determined based on experimental thermal histories data throughout the die and inside the casting which were recorded by fine type-K thermocouples. With measured temperatures, heat flux and IHTC were evaluated using the polynomial curve fitting method. The results show that the wall thickness affects IHTC peak values significantly. The IHTC value for the thick step is higher than that for the thin steps.

BOOSTER CHLORINATION FOR MANAGING DISINFECTANT RESIDUALS

EPA Science Inventory

Booster chlorination is an approach to residual maintenance in which chlorine is applied at strategic locations within the distribution system. Situations in which booster chlorination may be most effective for maintaining a residual are explained informally in the context of a ...

Identifying information that promotes belt-positioning booster use. Volume 2, Appendices

DOT National Transportation Integrated Search

2008-07-01

Many parents with low educational attainment prematurely graduate their children to seat belt restraint rather than use belt-positioning booster seats. This study aimed to identify interventions that promoted booster seat use among this population. F...

9. VIEW OF BOOSTER STATION 3 INTERIOR, FACING NORTHEAST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. VIEW OF BOOSTER STATION 3 INTERIOR, FACING NORTHEAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

6. VIEW OF BOOSTER STATION 2 INTERIOR, FACING WEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. VIEW OF BOOSTER STATION 2 INTERIOR, FACING WEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

12. VIEW OF BOOSTER STATION 4 INTERIOR, FACING SOUTHWEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. VIEW OF BOOSTER STATION 4 INTERIOR, FACING SOUTHWEST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

3. VIEW OF BOOSTER STATION 1 INTERIOR, FACING EAST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. VIEW OF BOOSTER STATION 1 INTERIOR, FACING EAST - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

Space shuttle system program definition. Volume 4: Cost and schedule report

NASA Technical Reports Server (NTRS)

1972-01-01

The supporting cost and schedule data for the second half of the Space Shuttle System Phase B Extension Study is summarized. The major objective for this period was to address the cost/schedule differences affecting final selection of the HO orbiter space shuttle system. The contending options under study included the following booster launch configurations: (1) series burn ballistic recoverable booster (BRB), (2) parallel burn ballistic recoverable booster (BRB), (3) series burn solid rocket motors (SRM's), and (4) parallel burn solid rocket motors (SRM's). The implications of varying payload bay sizes for the orbiter, engine type for the ballistics recoverable booster, and SRM motors for the solid booster were examined.

DETAIL VIEW OF BASE OF CAST IRON TOWER SHOWING THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW OF BASE OF CAST IRON TOWER SHOWING THE FABRICATING MARK OF STARBUCK IRON WORKS, TROY, NY - Bidwell Bar Suspension Bridge & Stone Toll House, Near Lake Oroville (moved from fork of Feather River), Oroville, Butte County, CA

Robustness of Ability Estimation to Multidimensionality in CAST with Implications to Test Assembly

ERIC Educational Resources Information Center

Zhang, Yanwei; Nandakumar, Ratna

2006-01-01

Computer Adaptive Sequential Testing (CAST) is a test delivery model that combines features of the traditional conventional paper-and-pencil testing and item-based computerized adaptive testing (CAT). The basic structure of CAST is a panel composed of multiple testlets adaptively administered to examinees at different stages. Current applications…

Species-specific predictive models of developmental toxicity using the ToxCast chemical library

EPA Science Inventory

EPA’s ToxCastTM project is profiling the in vitro bioactivity of chemicals to generate predictive models that correlate with observed in vivo toxicity. In vitro profiling methods are based on ToxCast data, consisting of over 600 high-throughput screening (HTS) and high-content sc...

Development of an Optimization Methodology for the Aluminum Alloy Wheel Casting Process

NASA Astrophysics Data System (ADS)

Duan, Jianglan; Reilly, Carl; Maijer, Daan M.; Cockcroft, Steve L.; Phillion, Andre B.

2015-08-01

An optimization methodology has been developed for the aluminum alloy wheel casting process. The methodology is focused on improving the timing of cooling processes in a die to achieve improved casting quality. This methodology utilizes (1) a casting process model, which was developed within the commercial finite element package, ABAQUS™—ABAQUS is a trademark of Dassault Systèms; (2) a Python-based results extraction procedure; and (3) a numerical optimization module from the open-source Python library, Scipy. To achieve optimal casting quality, a set of constraints have been defined to ensure directional solidification, and an objective function, based on the solidification cooling rates, has been defined to either maximize, or target a specific, cooling rate. The methodology has been applied to a series of casting and die geometries with different cooling system configurations, including a 2-D axisymmetric wheel and die assembly generated from a full-scale prototype wheel. The results show that, with properly defined constraint and objective functions, solidification conditions can be improved and optimal cooling conditions can be achieved leading to process productivity and product quality improvements.

Closeup view of the Solid Rocket Booster (SRB) Forward Skirt, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the Solid Rocket Booster (SRB) Forward Skirt, Frustum and Nose Cap mated assembly undergoing final preparations in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center. In this view the access panel on the Forward Skirt is removed and you can see a small portion of the interior of the Forward Skirt. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

STS-26 solid rocket booster post flight structural assessment

NASA Technical Reports Server (NTRS)

Herda, David A.; Finnegan, Charles J.

1988-01-01

A post flight assessment of the Space Shuttle's Solid Rocket Boosters was conducted at the John F. Kennedy Space Center in Florida after the launch of STS-26. The two boosters were inspected for structural damage and the results of this inspection are presented. Overall, the boosters were in good condition. However, there was some minor damage attributed to splash down. Some of this damage is a recurring problem. Explanations of these problems are provided.

NASA SLS Booster Nozzle Plug Pieces Fly During Test

NASA Image and Video Library

2016-06-28

On June 28, a test version of the booster that will help power NASA's new rocket, the Space Launch System, fired up at nearly 6,000 degrees Fahrenheit for a successful, two-minute qualification test at Orbital ATK's test facilities in Promontory, Utah. This video shows the booster's nozzle plug intentionally breaking apart. The smoky ring coming off the booster is condensed water vapor created by a pressure difference between the motor gas and normal air. The nozzle plug is an environmental barrier to prevent heat, dust and moisture from getting inside the booster before it ignites. The plug isn't always part of a static test but was included on this one due to changes made to the hardware. The foam on the plug is denser than previous NASA launch vehicles, as the engines are now in the same plane as the boosters. A numbered grid was placed on the exterior of the plug before the test so the pieces retrieved could support plug breakup assessment and reconstruction. Along with video, collecting the pieces helps determine the size and speed of them when they break apart. Nozzle plug pieces were found as far as 1,500 to 2,000 feet away from the booster. This is the last full-scale qualification test for the booster before the first, uncrewed flight of SLS with the Orion spacecraft in 2018.

Antibody persistence of two pentavalent DTwP-HB-Hib vaccines to the age of 15-18 months, and response to the booster dose of quadrivalent DTwP-Hib vaccine.

PubMed

Sharma, Hitt; Yadav, Sangeeta; Lalwani, Sanjay; Kapre, Subhash; Jadhav, Suresh; Parekh, Sameer; Palkar, Sonali; Ravetkar, Satish; Bahl, Sunil; Kumar, Rakesh; Shewale, Sunil

2013-01-07

Antibody persistence in children following three doses of primary vaccination with diphtheria, tetanus, whole-cell-pertussis (DTwP), hepatitis B, and Haemophilus influenzae type b (Hib) vaccines (SIIL Pentavac vaccine vs. Easyfive(®) of Panacea Biotec), and response to the booster dose of DTwP-Hib (Quadrovax(®)) vaccine. Children who completed their primary immunization were assessed for antibodies at 15-18 months of age, and then given a booster dose of DTwP-Hib vaccine. Reactogenicity and safety of the booster dose was evaluated. Both pentavalent vaccines demonstrated a good immune response at 15-18 months. Following the booster dose, all vaccinated subjects achieved protective titers against diphtheria, tetanus and Hib, whereas the response to pertussis antigen was ~78%. Fever and irritability was noted in 24%, local pain in 51%, and swelling in 36% of the children following booster dose. Primary immunization with either pentavalent vaccine induced an excellent immunity lasting till the second year of life. A booster dose with DTwP-Hib (Quadrovax(®)) vaccine effectuated a good anamnestic response to all vaccine components, being specially strong for Hib in children previously vaccinated with SIIL liquid pentavalent vaccine (Pentavac(®)). Also, the safety profile of SIIL quadrivalent vaccine (Quadrovax(®)) administered as booster dose was acceptable. Copyright © 2012 Elsevier Ltd. All rights reserved.

Numerical simulation of the casting process of titanium tooth crowns and bridges.

PubMed

Wu, M; Augthun, M; Wagner, I; Sahm, P R; Spiekermann, H

2001-06-01

The objectives of this paper were to simulate the casting process of titanium tooth crowns and bridges; to predict and control porosity defect. A casting simulation software, MAGMASOFT, was used. The geometry of the crowns with fine details of the occlusal surface were digitized by means of laser measuring technique, then converted and read in the simulation software. Both mold filling and solidification were simulated, the shrinkage porosity was predicted by a "feeding criterion", and the gas pore sensitivity was studied based on the mold filling and solidification simulations. Two types of dental prostheses (a single-crown casting and a three-unit-bridge) with various sprue designs were numerically "poured", and only one optimal design for each prosthesis was recommended for real casting trial. With the numerically optimized design, real titanium dental prostheses (five replicas for each) were made on a centrifugal casting machine. All the castings endured radiographic examination, and no porosity was detected in the cast prostheses. It indicates that the numerical simulation is an efficient tool for dental casting design and porosity control. Copyright 2001 Kluwer Academic Publishers

A Comparative Study of Hot Deformation Behaviors for Sand Casting and Centrifugal Casting Q235B Flange Blanks

NASA Astrophysics Data System (ADS)

Qin, Fangcheng; Li, Yongtang; Ju, Li

2017-03-01

Hot compression tests of sand casting and centrifugal casting Q235B flange blanks were performed at strain rate range of 0.01-5 s-1 and temperature range of 850-1,150 °C. The evolutions of microstructure and texture were revealed. The constitutive models based on Arrhenius constitutive modeling were proposed by considering the effects of strain on material constants. The results show that recrystallization in centrifugal casting Q235B is more apparent than that in sand casting, resulting in the finer grains and lower flow stress for centrifugal casting Q235B. The intensities of textures slightly weaken with the increase of temperature. At 1,050 °C and 5 s-1, the textures of sand casting are characterized by strong {001}<100> and {001}<110>, which are related with severe deformation, while the textures of centrifugal casting are composed of {110}<110> and {111}<112>, which are related with dynamic recovery and shear deformation. A good agreement between the predicted and experimental flow stress is achieved and demonstrates that the proposed constitutive models are reliable.

Development of a new casting method to fabricate U–Zr alloy containing minor actinides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jong Hwan Kim; Hoon Song; Hyung Tae Kim

2014-01-01

Metal fuel slugs of U–Zr alloys for a sodium-cooled fast reactor (SFR) have conventionally been fabricated using an injection casting method. However, casting alloys containing volatile radioactive constituents, such as Am, are problematic in a conventional injection casting method. As an alternative fabrication method, low pressure gravity casting has been developed. Casting soundness, microstructural characteristics, alloying composition, density, and fuel losses were evaluated for the following as-cast fuel slugs: U–10 wt% Zr, U–10 wt% Zr–5 wt% RE, and U–10 wt% Zr–5 wt% RE–5 wt% Mn. The U and Zr contents were uniform throughout the matrix, and impurities such as oxyen,more » carbon, and nitrogen satisfied the specification of total impurities less than 2,000 ppm. The appearance of the fuel slugs was generally sound, and the internal integrity was shown to be satisfactory based on gamma-ray radiography. In a volatile surrogate casting test, the U–Zr–RE–Mn fuel slug showed that nearly all of the manganese was retained when casting was done under an inert atmosphere.« less

Development and utilization of USGS ShakeCast for rapid post-earthquake assessment of critical facilities and infrastructure

USGS Publications Warehouse

Wald, David J.; Lin, Kuo-wan; Kircher, C.A.; Jaiswal, Kishor; Luco, Nicolas; Turner, L.; Slosky, Daniel

2017-01-01

The ShakeCast system is an openly available, near real-time post-earthquake information management system. ShakeCast is widely used by public and private emergency planners and responders, lifeline utility operators and transportation engineers to automatically receive and process ShakeMap products for situational awareness, inspection priority, or damage assessment of their own infrastructure or building portfolios. The success of ShakeCast to date and its broad, critical-user base mandates improved software usability and functionality, including improved engineering-based damage and loss functions. In order to make the software more accessible to novice users—while still utilizing advanced users’ technical and engineering background—we have developed a “ShakeCast Workbook”, a well documented, Excel spreadsheet-based user interface that allows users to input notification and inventory data and export XML files requisite for operating the ShakeCast system. Users will be able to select structure based on a minimum set of user-specified facility (building location, size, height, use, construction age, etc.). “Expert” users will be able to import user-modified structural response properties into facility inventory associated with the HAZUS Advanced Engineering Building Modules (AEBM). The goal of the ShakeCast system is to provide simplified real-time potential impact and inspection metrics (i.e., green, yellow, orange and red priority ratings) to allow users to institute customized earthquake response protocols. Previously, fragilities were approximated using individual ShakeMap intensity measures (IMs, specifically PGA and 0.3 and 1s spectral accelerations) for each facility but we are now performing capacity-spectrum damage state calculations using a more robust characterization of spectral deamnd.We are also developing methods for the direct import of ShakeMap’s multi-period spectra in lieu of the assumed three-domain design spectrum (at 0.3s for constant acceleration; 1s or 3s for constant velocity and constant displacement at very long response periods). As part of ongoing ShakeCast research and development, we will also explore the use of ShakeMap IM uncertainty estimates and evaluate the assumption of employing multiple response spectral damping values rather than the single 5%-damped value currently employed. Developing and incorporating advanced fragility assignments into the ShakeCast Workbook requires related software modifications and database improvements; these enhancements are part of an extensive rewrite of the ShakeCast application.

Chemical-Gene Interactions from ToxCast Bioactivity Data ...

EPA Pesticide Factsheets

Characterizing the effects of chemicals in biological systems is often summarized by chemical-gene interactions, which have sparse coverage in the literature. The ToxCast chemical screening program has produced bioactivity data for nearly 2000 chemicals and over 450 gene targets. To evaluate the information gained from the ToxCast project, a ToxCast bioactivity network was created comprising ToxCast chemical-gene interactions based on assay data and compared to a chemical-gene association network from literature. The literature network was compiled from PubMed articles, excluding ToxCast publications, mapped to genes and chemicals. Genes were identified by curated associations available from NCBI while chemicals were identified by PubChem submissions. The frequencies of chemical-gene associations from the literature network were log-scaled and then compared to the ToxCast bioactivity network. In total, 140 times more chemical-gene associations were present in the ToxCast network in comparison to the literature-derived network highlighting the vast increase in chemical-gene interactions putatively elucidated by the ToxCast research program. There were 165 associations found in the literature network that were reproduced by ToxCast bioactivity data, and 336 associations in the literature network were not reproduced by the ToxCast bioactivity network. The literature network relies on the assumption that chemical-gene associations represent a true chemical-gene inte

Analysis of SRB reentry acoustic environments. [aeroacoustic spectra determined from wind tunnel tests

NASA Technical Reports Server (NTRS)

Coffin, T.; Dandridge, R. E.; Haddock, U. W.

1979-01-01

Space shuttle solid rocket booster reentry aeroacoustic environments were estimated. Particular emphasis was given to the aft skirt/exit plane region for the Mach number regime 0.6 = or greater than M infinity = or less than 3.5. The analysis is based on the evaluation of wind tunnel model results in conjunction with Monte Carlo simulation of trajectory parameters. The experimental approach is described as well as the evaluation process utilized. Predicted environments are presented in terms of one-third octave band spectra representing space averaged values for critical regions on the solid rocket booster.

Recession Curve Generation for the Space Shuttle Solid Rocket Booster Thermal Protection System Coatings

NASA Technical Reports Server (NTRS)

Kanner, Howard S.; Stuckey, C. Irvin; Davis, Darrell W.; Davis, Darrell (Technical Monitor)

2002-01-01

Ablatable Thermal Protection System (TPS) coatings are used on the Space Shuttle Vehicle Solid Rocket Boosters in order to protect the aluminum structure from experiencing excessive temperatures. The methodology used to characterize the recession of such materials is outlined. Details of the tests, including the facility, test articles and test article processing are also presented. The recession rates are collapsed into an empirical power-law relation. A design curve is defined using a 95-percentile student-t distribution. based on the nominal results. Actual test results are presented for the current acreage TPS material used.

Hybrid propulsion technology program: Phase 1. Volume 3: Thiokol Corporation Space Operations

NASA Technical Reports Server (NTRS)

Schuler, A. L.; Wiley, D. R.

1989-01-01

Three candidate hybrid propulsion (HP) concepts were identified, optimized, evaluated, and refined through an iterative process that continually forced improvement to the systems with respect to safety, reliability, cost, and performance criteria. A full scale booster meeting Advanced Solid Rocket Motor (ASRM) thrust-time constraints and a booster application for 1/4 ASRM thrust were evaluated. Trade studies and analyses were performed for each of the motor elements related to SRM technology. Based on trade study results, the optimum HP concept for both full and quarter sized systems was defined. The three candidate hybrid concepts evaluated are illustrated.

Identifying information that promotes belt-positioning booster use. Volume 1, Summary and findings

DOT National Transportation Integrated Search

2008-07-01

Many parents with low educational attainment prematurely graduate their children to seat belt restraint rather than use belt-positioning booster seats. This study aimed to identify interventions that promoted booster seat use among this population. F...

13. VIEW OF BOOSTER STATION 4 CHLORINATOR INTERIOR, FACING NORTH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW OF BOOSTER STATION 4 CHLORINATOR INTERIOR, FACING NORTH - Nevada Test Site, Frenchman Flat Test Facility, Well Five Booster Stations, Intersection of 5-03 Road & Short Pole Line Road, Area 5, Frenchman Flat, Mercury, Nye County, NV

Repair welding of cast iron coated electrodes

NASA Astrophysics Data System (ADS)

Żuk, M.; Górka, J.; Dojka, R.; Czupryński, A.

2017-08-01

Welding cast iron is a complex production procedure. Repair welding was used to repair damaged or poorly made castings. This is due to a tendency to cracking of the material during welding as well as after it. Welding cast iron can be carried out on hot or on cold. Hot welding requires high heat material and the use of welding material in the form of cast iron. In the case of cold welding, it is possible to use different materials. Mostly used filler metals are nickel and copper based. The work shows the course of research concerning repairmen of ductile iron with arc welding method. For the reparation process four types of ESAB company coated electrodes dedicated for cast iron were used with diameter 3.2 and 4 mm: ES 18-8-6B (4mm), EB 150 (4mm), OK NiCl, EŻM. In the cast iron examined during the testing grooves were made using plasma methods, in order to simulate the removed casting flaws. Then the welding process with coated electrodes was executed. The process utilized low welding current row of 100A, so there would only be a small amount of heat delivered to the heat affected zone (HAZ). Short stitches were made, after welding it was hammered, in order to remove stresses. After the repair welding the part of studies commenced which purpose was finding surface defects using visual testing (VT) and penetration testing (PT). In the second part, a series of macro and microscopic studies were executed witch the purpose of disclosuring the structure. Then the hardness tests for welds cross sections were performed. An important aspect of welding cast iron is the colour of the padding weld after welding, more precisely the difference between the base material and padding weld, the use of different materials extra gives the extra ability to select the best variant. The research of four types of coated electrode was executed, based on the demands the best option in terms of aesthetic, strength and hardness.

Novel technologies for the lost foam casting process

NASA Astrophysics Data System (ADS)

Jiang, Wenming; Fan, Zitian

2018-03-01

Lost foam casting (LFC) is a green precision casting process categorized as a near net forming technology. Yet, despite its popularity, it still suffers from some technological problems, such as poor filling ability of the castings, coarse and non-dense microstructure, low mechanical properties for the Al and Mg LFC processes, and defective carburization for the low carbon steel LFC process. These drawbacks restrict the development and widespread application of the LFC process. To solve these problems, the present study developed several novel LFC technologies, namely, LFC technologies under vacuum and low pressure, vibration solidification, and pressure solidification conditions; expendable shell casting technology; and preparation technology of bimetallic castings based on the LFC process. The results showed that the LFC under vacuum and low pressure evidently improved the filling ability and solved the oxidization problem of the alloys, which is suitable for producing complex and thinwall castings. The vibration and pressure solidifications increased the compactness of the castings and refined the microstructure, significantly improving the mechanical properties of the castings. The expendable shell casting technology could solve the pore, carburization, and inclusion defects of the traditional LFC method, obtaining castings with acceptable surface quality. Moreover, the Al/Mg and Al/Al bimetallic castings with acceptable metallurgical bonding were successfully fabricated using the LFC process. These proposed novel LFC technologies can solve the current technological issues and promote the technological progress of the LFC process.

Improvement of food packaging related properties in whey protein isolate‑based nanocomposite films and coatings by addition of montmorillonite nanoplatelets

NASA Astrophysics Data System (ADS)

Schmid, Markus; Merzbacher, Sarah; Brzoska, Nicola; Müller, Kerstin; Jesdinszki, Marius

2017-11-01

In the present study the effects of the addition of montmorillonite (MMT) nanoplatelets on whey protein isolate (WPI)-based nanocomposite films and coatings were investigated. The main objective was the development of WPI-based MMT-nanocomposites with enhanced barrier and mechanical properties. WPI-based nanocomposite cast-films and coatings were prepared by dispersing 0 % (reference sample), 3 %, 6 %, 9 % (w/w protein) MMT, or, depending on the protein concentration, also 12 % and 15 % (w/w protein) MMT into native WPI-based dispersions, followed by subsequent denaturation during the drying and curing process. The natural MMT nanofillers could be randomly dispersed into film-forming WPI-based nanodispersions, displaying good compatibility with the hydrophilic biopolymer matrix. As a result, by addition of 15 % (w/w protein) MMT into 10 % (w/w dispersion) WPI-based cast-films or coatings, the oxygen permeability (OP) was reduced by 91 % for glycerol-plasticized and 84 % for sorbitol-plasticized coatings, water vapor transmission rate (WVTR) was reduced by 58 % for sorbitol-plasticized cast-films. Due to the addition of MMT- nanofillers the Young’s modulus and tensile strength improved by 315 % and 129 %, respectively, whereas elongation at break declined by 77 % for glycerol-plasticized cast-films. In addition, comparison of plasticizer type revealed that sorbitol-plasticized cast-films were generally stiffer and stronger, but less flexible compared glycerol-plasticized cast-films. Viscosity measurements demonstrated good processability and suitability for up-scaled industrial processes of native WPI-based nanocomposite dispersions, even at high nanofiller-loadings. These results suggest that the addition of natural MMT- nanofillers into native WPI-based matrices to form nanocomposite films and coatings holds great potential to replace well-established, fossil-based packaging materials for at least certain applications such as oxygen barriers as part of multilayer flexible packaging films.

Advanced rotary engine components utilizing fiber reinforced Mg castings

NASA Technical Reports Server (NTRS)

Goddard, D.; Whitman, W.; Pumphrey, R.; Lee, C.-M.

1986-01-01

Under a two-phase program sponsored by NASA, the technology for producing advanced rotary engine components utilizing graphite fiber-reinforced magnesium alloy casting is being developed. In Phase I, the successful casting of a simulated intermediate housing was demonstrated. In Phase II, the goal is to produce an operating rotor housing. The effort involves generation of a material property data base, optimization of parameters, and development of wear- and corrosion-resistant cast surfaces and surface coatings. Results to date are described.

An objective assessment of safety to drive in an upper limb cast.

PubMed

Stevenson, H L; Peterson, N; Talbot, C; Dalal, S; Watts, A C; Trail, I A

2013-03-01

Patients managed with upper limb cast immobilization often seek advice about driving. There is very little published data to assist in decision making, and advice given varies between healthcare professionals. There are no specific guidelines available from the UK Drivers and Vehicles Licensing Agency, police, or insurance companies. Evidence-based guidelines would enable clinicians to standardize the advice given to patients. Six individuals (three male, three female; mean age 36 years, range 27-43 years) were assessed by a mobility occupational therapist and driving standards agency examiner while completing a formal driving test in six different types of upper limb casts (above-elbow, below-elbow neutral, and below-elbow cast incorporating the thumb [Bennett's cast]) on both left and right sides. Of the 36 tests, participants passed 31 tests, suggesting that most people were able to safely drive with upper limb cast immobilization. However, driving in a left above-elbow cast was considered unsafe.

A Winning Cast

NASA Technical Reports Server (NTRS)

2001-01-01

Howmet Research Corporation was the first to commercialize an innovative cast metal technology developed at Auburn University, Auburn, Alabama. With funding assistance from NASA's Marshall Space Flight Center, Auburn University's Solidification Design Center (a NASA Commercial Space Center), developed accurate nickel-based superalloy data for casting molten metals. Through a contract agreement, Howmet used the data to develop computer model predictions of molten metals and molding materials in cast metal manufacturing. Howmet Metal Mold (HMM), part of Howmet Corporation Specialty Products, of Whitehall, Michigan, utilizes metal molds to manufacture net shape castings in various alloys and amorphous metal (metallic glass). By implementing the thermophysical property data from by Auburn researchers, Howmet employs its newly developed computer model predictions to offer customers high-quality, low-cost, products with significantly improved mechanical properties. Components fabricated with this new process replace components originally made from forgings or billet. Compared with products manufactured through traditional casting methods, Howmet's computer-modeled castings come out on top.

HLA-DPB1 and anti-HBs titer kinetics in hepatitis B booster recipients who completed primary hepatitis B vaccination during infancy.

PubMed

Wu, T-W; Chu, C-C; Liao, H-W Chang; Lin, S-K; Ho, T-Y; Lin, M; Lin, H H; Wang, L-Y

2014-01-01

Previously we reported significant associations of the human leukocyte antigen (HLA)-DPB1 05:01 with memory against hepatitis B (HB) vaccination. However, the effects of HLA-DPB1 on antibodies to hepatitis B surface antigen (anti-HBs) kinetics were not explored. We followed up a cohort of 1974 HB booster recipients and quantified their 1-month and 1-year post-booster anti-HBs titers. A total of 681 subjects were randomly selected and typed for HLA-DPB1. We found that male subjects, undetectable pre-booster titers, and 05:01 homozygotes led to significantly lower post-booster anti-HBs titers. The geometric means (95% confidence interval (CI)) of 1-month post-booster anti-HBs titers were 4.68 (2.69-8.12), 23.01 (14.96-35.40) and 50.06 (27.20-92.13) mIU ml(-1) for subjects carrying two, one and no HLA-DPB1 05:01 allele. The corresponding figures for 1-year post-booster anti-HBs titers were 1.26 (0.73-2.18), 4.72 (3.08-7.25) and 7.32 (3.75-13.56) mIU ml(-1). There were significant associations of post-booster anti-HBs titers with the number of HLA-DPB1 risk and protective alleles. Among booster responders, anti-HBs decay rates were significantly reduced in subjects who had detectable pre-booster anti-HBs titers and the HLA-DPB1 05:01 allele. Our results indicated that HLA-DPB1 influences the kinetics of anti-HBs. The long-term memory against hepatitis B surface antigen (HBsAg) and the residual serum titers of anti-HBs after HB vaccination may be influenced by different mechanisms as evidenced by their inverse trend of associations with the 05:01 allele.

Persistence of antibodies six years after booster vaccination with inactivated vaccine against Japanese encephalitis.

PubMed

Paulke-Korinek, Maria; Kollaritsch, Herwig; Kundi, Michael; Zwazl, Ines; Seidl-Friedrich, Claudia; Jelinek, Tomas

2015-07-09

Japanese Encephalitis (JE) virus occurs in wide regions of Asia with over 3 billion people living in areas at risk for JE. An estimated 68,000 clinical cases of JE occur every year, and vaccination is the most effective prophylactic measure. One internationally licensed vaccine containing the inactivated JE virus strain SA14-14-2 is Ixiaro (Valneva, Austria). According to recommendations, basic immunization consists of vaccinations on day 0, day 28, and a booster dose 12-24 months later. Protection in terms of neutralizing antibody titers has been assessed up to 12 months after the third dose of the vaccine. The current investigation was designed to evaluate antibody decline over time and to predict long-term duration of seroprotection after a booster dose. In a preceding trial, volunteers received basic immunization (day 0, day 28) and one booster dose against JE 15 months later. A follow up blood draw 6 years following their booster dose was carried out in 67 subjects. For antibody testing, a 50% plaque reduction neutralization test (PRNT50-test) was used. PRNT50 values of 10 and above are surrogate levels of protection according to WHO standards. Seventy-six months following the booster dose, 96% of the tested subjects had PRNT50 titers of 10 or higher. Geometric mean titer (GMT) was 148 (95% CI confidence interval: 107-207). Antibody titers were lower in volunteers 50 years of age and older. Vaccination history against other flaviviruses (yellow fever or tick borne encephalitis) did not significantly influence PRNT50 titers. A two-step log-linear decline model predicted protection against JE of approximately 14 years after the booster dose. Six years after a booster dose against JE, long-term protection could be demonstrated. According to our results, further booster doses should be scheduled 10 years following the first booster dose. Copyright © 2015 Elsevier Ltd. All rights reserved.

Antibody persistence and the effect of a booster dose given 5, 10 or 15 years after vaccinating preadolescents with a recombinant hepatitis B vaccine.

PubMed

Gilca, Vladimir; De Serres, Gaston; Boulianne, Nicole; Murphy, Donald; De Wals, Philippe; Ouakki, Manale; Trudeau, Gisele; Massé, Richard; Dionne, Marc

2013-01-07

The persistence of antibody obtained post-vaccination of preadolescents with three doses of Engerix-B and the effect of a booster administered 5, 10 or 15 years later were monitored in 663 vaccinees. Five, 10 and 15 years post-vaccination >94% of subjects had detectable antibodies and 88.2%, 86.4% and 76.7% had a titre ≥10 IU/L; GMTs were 269 IU/L, 169 IU/L and 51 IU/L, respectively; 99.1-100% vaccinees reached a titre ≥10 IU/l post-booster. GMTs were 118012 IU/L, 32477 IU/L, and 13946 IU/L when the booster was administered 5, 10 or 15 years post-vaccination, respectively. We conclude that vaccination induces immunity in the great majority of vaccinees for at least 15 years. The response to a booster dose suggests persistence of immune memory in almost all vaccinees. Although a booster dose increases substantially anti-HBs titres, the clinical relevance of such an increase remains unknown. These results do not support the need of a booster for at least 15 years when vaccinating preadolescents with Engerix-B. Copyright © 2012 Elsevier Ltd. All rights reserved.

AIS/DOE Technology Roadmap Program: Strip Casting: Anticipating New Routes To Steel Sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prof. Alan W. Camb; Prof. Anthony Rollett

2001-08-31

To determine the potential for strip casting in the steel industry and to develop the fundamental knowledge necessary to allow the role of strip casting in the modern steel industry to be understood. Based upon a study of carbon steel strip castings that were either produced for the program at British Steel or were received from a pre-commercial production machine, the following conclusions were made. Strip casting of carbon steels is technically feasible for sheet material from slightly less than 1 mm thick to 3 mm thick, and, assuming that it is economically viable, it will be first applied inmore » carbon steel markets that do not require stringent surface quality or extensive forming. The potential of strip casting as a casting process to be developed for steel castings is very high as the cast strip has some very novel characteristics. Direct cast carbon strip has better surface quality, shape and profile than any other casting process currently available. The more rapidly solidified structure of direct cast strip tends to be strong with low ductility; however, with adequate thermal treatment, it is possible to develop a variety of properties from the same grade. The process is more amenable at this time to production tonnages per year of the order of 500,000 tons and as such will first find niche type applications. This technology is an additional technology for steel production and will be in addition to, rather than a replacement for, current casting machines.« less

Influence of Ni Interlayer on Microstructure and Mechanical Properties of Mg/Al Bimetallic Castings

NASA Astrophysics Data System (ADS)

Liu, Ning; Liu, Canchun; Liang, Chunyong; Zhang, Yongguang

2018-05-01

Dissimilar joining of magnesium and aluminum using a compound casting process was investigated in the present work. For the first time, a Ni interlayer prepared by plasma spraying was inserted between the two base metals to improve the interfacial characteristics. Examination of the interfacial regions using scanning electron microscopy, energy-dispersive X-ray spectroscopy, electron probe microanalysis, and X-ray diffraction revealed the formation of a three-layered interface between Mg and Al without the interlayer. The thickness of the interface was approximately 600 μm when the casting was performed at 700 °C and increased with increasing casting temperature. However, with the addition of the Ni interlayer, the Al-Mg reaction was successfully prevented, and metallurgical bonding between the Ni interlayer and two base metals was achieved at a casting temperature of 700 °C. Upon increasing this temperature, Mg-Ni and Al-Ni intermetallics were generated at the separate interfaces. The shear strength of the Mg/Al bimetallic castings with the Ni interlayer was substantially improved compared with that of the direct Mg/Al joint, with a maximum value of 25.4 MPa achieved at 700 °C. Fracture occurred mainly along the Mg/Ni interface for the Mg/Ni/Al multilayer structure castings.

High-Temperature Creep Behaviour and Positive Effect on Straightening Deformation of Q345c Continuous Casting Slab

NASA Astrophysics Data System (ADS)

Guo, Long; Zhang, Xingzhong

2018-03-01

Mechanical and creep properties of Q345c continuous casting slab subjected to uniaxial tensile tests at high temperature were considered in this paper. The minimum creep strain rate and creep rupture life equations whose parameters are calculated by inverse-estimation using the regression analysis were derived based on experimental data. The minimum creep strain rate under constant stress increases with the increase of the temperature from 1000 °C to 1200 °C. A new casting machine curve with the aim of fully using high-temperature creep behaviour is proposed in this paper. The basic arc segment is cancelled in the new curve so that length of the straightening area can be extended and time of creep behaviour can be increased significantly. For the new casting machine curve, the maximum straightening strain rate at the slab surface is less than the minimum creep strain rate. So slab straightening deformation based on the steel creep behaviour at high temperature can be carried out in the process of Q345c steel continuous casting. The effect of creep property at high temperature on slab straightening deformation is positive. It is helpful for the design of new casting machine and improvement of old casting machine.

Identifying strategies to improve the effectiveness of booster seat laws

DOT National Transportation Integrated Search

2008-05-01

The objective of this project was to identify strategies to improve the effectiveness of booster seat laws. The project explored the possible factors that relate to the use and nonuse of booster seats, and examined the attitudes of law enforcement of...

Booster seat law enforcement : examples from Delaware, New Jersey, Pennsylvania, and Washington.

DOT National Transportation Integrated Search

2010-02-01

The objective of this study was to evaluate the implementation of State booster seat laws : (enhanced child restraint laws) and examine the most effective strategies that law enforcement agencies can : use to enforce booster seat laws. The research i...

Space transportation booster engine configuration study. Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

1989-01-01

The objective of the Space Transportation Booster Engine (STBE) Configuration Study is to contribute to the Advanced Launch System (ALS) development effort by providing highly reliable, low cost booster engine concepts for both expendable and reusable rocket engines. The objectives of the Space Transportation Booster Engine (STBE) Configuration Study were to identify engine configurations which enhance vehicle performance and provide operational flexibility at low cost, and to explore innovative approaches to the follow-on full-scale development (FSD) phase for the STBE.

First Test Results of the bERLinPro 2-cell Booster Cavities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burrill, Andrew; Anders, W.; Frahm, A.

2015-09-01

The bERLinPro Energy Recovery Linac (ERL) is currently being built at Helmholtz-Zentrum Berlin in order to study the physics of operating a high-current, a 100 mA, 50 MeV ERL utilizing all SRF cavity technology. This machine will utilize three unique SRF cryomodules for the photoinjector, booster and linac cryomodules respectively. The focus of this paper will be on the cavities contained within the booster cryomodule. Here there will be three 2-cell SRF cavities, based on the original design by Cornell University, but optimized to meet the needs of the project. All of the cavity fabrication, processing and testing was carriedmore » out at Jefferson Laboratory, where 4 cavities were produced, and the 3 cavities with the best RF performance were fitted with helium vessels for installation in the cryomodule. This paper will report on the test results of the cavities as measured in the vertical testing dewar at JLab after fabrication and again after outfitting with the helium vessels.« less

Comparative assessment of marginal accuracy of grade II titanium and Ni–Cr alloy before and after ceramic firing: An in vitro study

PubMed Central

Patil, Abhijit; Singh, Kishan; Sahoo, Sukant; Suvarna, Suraj; Kumar, Prince; Singh, Anupam

2013-01-01

Objective: The aims of the study are to assess the marginal accuracy of base metal and titanium alloy casting and to evaluate the effect of repeated ceramic firing on the marginal accuracy of base metal and titanium alloy castings. Materials and Methods: Twenty metal copings were fabricated with each casting material. Specimens were divided into 4 groups of 10 each representing base metal alloys castings without (Group A) and with metal shoulder margin (Group B), titanium castings without (Group C) and with metal shoulder margin (Group D). The measurement of fit of the metal copings was carried out before the ceramic firing at four different points and the same was followed after porcelain build-up. Results: Significant difference was found when Ni–Cr alloy samples were compared with Grade II titanium samples both before and after ceramic firings. The titanium castings with metal shoulder margin showed highest microgap among all the materials tested. Conclusions: Based on the results that were found and within the limitations of the study design, it can be concluded that there is marginal discrepancy in the copings made from Ni–Cr and Grade II titanium. This marginal discrepancy increased after ceramic firing cycles for both Ni–Cr and Grade II titanium. The comparative statistical analysis for copings with metal-collar showed maximum discrepancy for Group D. The comparative statistical analysis for copings without metal-collar showed maximum discrepancy for Group C. PMID:24926205

The association between booster seat use and risk of death among motor vehicle occupants aged 4-8: a matched cohort study.

PubMed

Rice, T M; Anderson, C L; Lee, A S

2009-12-01

To estimate the effectiveness of booster seats and of seatbelts in reducing the risk of child death during traffic collisions and to examine possible effect modification by various collision and vehicle characteristics. A matched cohort study was conducted using data from the Fatality Analysis Reporting System. Death risk ratios were estimated with conditional Poisson regression, bootstrapped coefficient standard errors, and multiply imputed missing values using chained equations. Estimated death risk ratios for booster seats used with seatbelts were 0.33 (95% CI 0.28 to 0.40) for children age 4-5 years and 0.45 (0.31 to 0.63) for children aged 6-8 years (Wald test of homogeneity p<0.005). The estimated risk ratios for seatbelt used alone were similar for the two age groups, 0.37 (0.32 to 0.43) and 0.39 (0.34 to 0.44) for ages 4-5 and 6-8, respectively (Wald p = 0.61). Estimated booster seat effectiveness was significantly greater for inbound seating positions (Wald p = 0.05) and during rollovers collisions (Wald p = 0.01). Significant variability in risk ratio estimates was not observed across levels of calendar year, vehicle model year, vehicle type, or land use. Seatbelts, used with or without booster seats, are highly effective in preventing death among motor vehicle occupants aged 4-8 years. Booster seats do not appear to improve the performance of seatbelts with respect to preventing death (risk ratio 0.92, 95% CI 0.79 to 1.08, comparing seatbelts with boosters to seatbelts alone), but because several studies have found that booster seats reduce non-fatal injury severity, clinicians and injury prevention specialists should continue to recommend the use of boosters to parents of young children.

Materials for Advanced Ultrasupercritical Steam Turbines Task 4: Cast Superalloy Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thangirala, Mani

The Steam Turbine critical stationary structural components are high integrity Large Shell and Valve Casing heavy section Castings, containing high temperature steam under high pressures. Hence to support the development of advanced materials technology for use in an AUSC steam turbine capable of operating with steam conditions of 760°C (1400°F) and 35 Mpa (5000 psia), Casting alloy selection and evaluation of mechanical, metallurgical properties and castability with robust manufacturing methods are mandated. Alloy down select from Phase 1 based on producability criteria and creep rupture properties tested by NETL-Albany and ORNL directed the consortium to investigate cast properties of Haynesmore » 282 and Haynes 263. The goals of Task 4 in Phase 2 are to understand a broader range of mechanical properties, the impact of manufacturing variables on those properties. Scale up the size of heats to production levels to facilitate the understanding of the impact of heat and component weight, on metallurgical and mechanical behavior. GE Power & Water Materials and Processes Engineering for the Phase 2, Task 4.0 Castings work, systematically designed and executed casting material property evaluation, multiple test programs. Starting from 15 lbs. cylinder castings to world’s first 17,000 lbs. poured weight, heavy section large steam turbine partial valve Haynes 282 super alloy casting. This has demonstrated scalability of the material for steam Turbine applications. Activities under Task 4.0, Investigated and characterized various mechanical properties of Cast Haynes 282 and Cast Nimonic 263. The development stages involved were: 1) Small Cast Evaluation: 4 inch diam. Haynes 282 and Nimonic 263 Cylinders. This provided effects of liquidus super heat range and first baseline mechanical data on cast versions of conventional vacuum re-melted and forged Ni based super alloys. 2) Step block castings of 300 lbs. and 600 lbs. Haynes 282 from 2 foundry heats were evaluated which demonstrated the importance of proper heat treat cycles for Homogenization, and Solutionizing parameters selection and implementation. 3) Step blocks casting of Nimonic 263: Carried out casting solidification simulation analysis, NDT inspection methods evaluation, detailed test matrix for Chemical, Tensile, LCF, stress rupture, CVN impact, hardness and J1C Fracture toughness section sensitivity data and were reported. 4) Centrifugal Casting of Haynes 282, weighing 1400 lbs. with hybrid mold (half Graphite and half Chromite sand) mold assembly was cast using compressor casing production tooling. This test provided Mold cooling rates influence on centrifugally cast microstructure and mechanical properties. Graphite mold section out performs sand mold across all temperatures for 0.2% YS; %Elongation, %RA, UTS at 1400°F. Both Stress-LMP and conditional Fracture toughness plots data were in the scatter band of the wrought alloy. 5) Fundamental Studies on Cooling rates and SDAS test program. Evaluated the influence of 6 mold materials Silica, Chromite, Alumina, Silica with Indirect Chills, Zircon and Graphite on casting solidification cooling rates. Actual Casting cooling rates through Liquidus to Solidus phase transition were measured with 3 different locations based thermocouples placed in each mold. Compared with solidification simulation cooling rates and measurement of SDAS, microstructure features were reported. The test results provided engineered casting potential methods, applicable for heavy section Haynes 282 castings for optimal properties, with foundry process methods and tools. 6) Large casting of Haynes 282 Drawings and Engineering FEM models and supplemental requirements with applicable specifications were provided to suppliers for the steam turbine proto type feature valve casing casting. Molding, melting and casting pouring completed per approved Manufacturing Process Plan during 2014 Q4. The partial valve casing was successfully cast after casting methods were validated with solidification simulation analysis and the casting met NDT inspection and acceptance criteria. Heat treated and sectioned to extract trepan samples at different locations comparing with cast on coupons test data. Material properties requisite for design, such as tensile, creep/rupture, LCF, Fracture Toughness, Charpy V-notch chemical analysis testing were carried out. The test results will be presented in the final report. The typical Haynes 282 large size Steam Turbine production casting from Order to Delivery foundry schedule with the activity break up is shown in Figures 107 and 108. • From Purchase Order placement to Casting pouring ~ 26 weeks. 1. Sales and commercial review 3 2. Engineering Drawings/models review 4 3. Pattern and core box manufacturing 6 4. Casting process engineering review 4 5. FEM and solidification simulation analysis 4 6. Gating & Feeder Attachments, Ceramic tiling 2 7. Molding and coremaking production scheduling 6 8. Melting planning and schedule 3 9. Pouring, cooling and shake out 2 • From Pouring to casting Delivery ~ 29 weeks 10. Shot blast and riser cutting, gates removal 3 11. Homogenizing , solutionizing HT furnace prep 4 12. Grinding, Fettling 2 13. Aging HT Cycle, cooling 2 14. VT and LPT NDT inspections 2 15. Radiographic inspection 4 16. Mechanical testing, Chemical analysis test certs 4 17. Casting weld repair upgrades and Aging PWHT 4 18. NDT after weld repairs and casting upgrades 3 19. Casting Final Inspection and test certifications 3 20. Package and delivery 2 Hence the Total Lead time from P.O to Casting delivery is approximately 55 weeks. The Task 4.2 and Task 4.3 activities and reporting completed.« less

The qualification of the shuttle booster separation motors

NASA Technical Reports Server (NTRS)

Chase, C. A.; Fisher, K. M.; Eoff, W.

1978-01-01

Four booster separation motors (BSM) located at each end of every solid rocket booster (SRB) provide the needed side force to separate the boosters from the external tank at booster burnout. Four BSMs at the top of the SRB are located in a box pattern in the nose cone frustum. The four BSMs at the aft end of the SRB are arranged side-by-side on the SRB aft skirt. Aspects of BSM design and performance are considered, taking into account a motor design/performance summary, the case design, the insulation, the grain design, the nozzle/aft closure design, the ignition system, the propellant, and the motor assembly. Details of motor testing are also discussed, giving attention to development testing, qualification testing, and flight testing.

Longitudinal emittance measurements in the Booster and AGS during the 2014 RHIC gold run

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeno, K.

2014-08-18

This note describes longitudinal emittance measurements that were made in the Booster and AGS during the 2014 RHIC Gold run. It also contains an overview of the longitudinal aspects of their setup during this run. Each bunch intended for RHIC is composed of beam from 4 Booster cycles, and there are two of them per AGS cycle. For each of the 8 Booster cycles required to produce the 2 bunches in the AGS, a beam pulse from EVIS is injected into the Booster and captured in four h=4 buckets. Then those bunches are accelerated to a porch where they aremore » merged into 2 bunches and then into 1 bunch.« less

Study on the Structures of Two Booster Pellets Having High Initiation Capacity

NASA Astrophysics Data System (ADS)

Shuang-Qi, Hu; Hong-Rong, Liu; Li-shuang, Hu; Xiong, Cao; Xiang-Chao, Mi; Hai-Xia, Zhao

2014-05-01

Insensitive munitions (IM) improve the survivability of both weapons and their associated platforms, which can lead to a reduction in casualties, mission losses, and whole life costs. All weapon systems contain an explosive train that needs to meet IM criteria but reliably initiate a main charge explosive. To ensure that these diametrically opposed requirements can be achieved, new highly effective booster charge structures were designed. The initiation capacity of the two booster pellets was studied using varied composition and axial-steel-dent methods. The results showed that the two new booster pellets can initiate standard main charge pellets with less explosive mass than the ordinary cylindrical booster pellet. The numerical simulation results were in good agreement with the experiment results.

KSC-2011-1886

NASA Image and Video Library

2011-02-28

CAPE CANAVERAL, Fla. -- The Solid Rocket Booster Retrieval Ship Freedom Star tows a booster to the dock at Hangar AF on Cape Canaveral Air Force Station in Florida. The booster was used during space shuttle Discovery's STS-133 launch from NASA Kennedy Space Center's Launch Pad 39A on Feb. 24. The shuttle’s two solid rocket booster casings and associated flight hardware are recovered in the Atlantic Ocean after every launch by Liberty Star and Freedom Star. The boosters impact the Atlantic about seven minutes after liftoff and the retrieval ships are stationed about 10 miles from the impact area at the time of splashdown. After the spent segments are processed, they will be transported to Utah, where they will be refurbished and stored, if needed. Photo credit: NASA/Jim Grossmann

KSC-2011-1859

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- The right spent booster from shuttle Discovery's final launch is seen bobbing in the Atlantic Ocean. Crew members from Liberty Star, one of NASA's solid rocket booster retrieval ships, will recover the parachute and tow the booster back to Port Canaveral in Florida. The shuttle’s two solid rocket booster casings and associated flight hardware are recovered in the Atlantic Ocean after every launch by Freedom Star and Liberty Star. The boosters impact the Atlantic about seven minutes after liftoff and the retrieval ships are stationed about 10 miles from the impact area at the time of splashdown. After the spent segments are processed, they will be transported to Utah, where they will be refurbished and stored, if needed. Photo credit: NASA/Frank Michaux

Closeup view of the Solid Rocket Booster (SRB) Frustum mounted ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Close-up view of the Solid Rocket Booster (SRB) Frustum mounted on ground support equipment in the Solid Rocket Booster Assembly and Refurbishment Facility at Kennedy Space Center as it is being prepared to be mated with the Nose Cap and Forward Skirt. The Frustum contains the three Main Parachutes, Altitude Switches and forward booster Separation Motors. The Separation Motors burn for one second to ensure the SRBs drift away from the External Tank and Orbiter at separation. The three main parachutes are deployed to reduce speed as the SRBs descend to a splashdown in the Atlantic Ocean where they are recovered refurbished and reused. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Tuning the properties of polyhydroxybutyrate films using acetic acid via solvent casting

PubMed Central

Anbukarasu, Preetam; Sauvageau, Dominic; Elias, Anastasia

2015-01-01

Biodegradable polyhydroxybutyrate (PHB) films were fabricated using acetic acid as an alternative to common solvents such as chloroform. The PHB films were prepared using a solvent casting process at temperatures ranging from 80 °C to 160 °C. The crystallinity, mechanical properties and surface morphology of the films cast at different temperatures were characterized and compared to PHB films cast using chloroform as a solvent. Results revealed that the properties of the PHB film varied considerably with solvent casting temperature. In general, samples processed with acetic acid at low temperatures had comparable mechanical properties to PHB cast using chloroform. This acetic acid based method is environmentally friendly, cost efficient and allows more flexible processing conditions and broader ranges of polymer properties than traditional methods. PMID:26640089

Tuning the properties of polyhydroxybutyrate films using acetic acid via solvent casting

NASA Astrophysics Data System (ADS)

Anbukarasu, Preetam; Sauvageau, Dominic; Elias, Anastasia

2015-12-01

Biodegradable polyhydroxybutyrate (PHB) films were fabricated using acetic acid as an alternative to common solvents such as chloroform. The PHB films were prepared using a solvent casting process at temperatures ranging from 80 °C to 160 °C. The crystallinity, mechanical properties and surface morphology of the films cast at different temperatures were characterized and compared to PHB films cast using chloroform as a solvent. Results revealed that the properties of the PHB film varied considerably with solvent casting temperature. In general, samples processed with acetic acid at low temperatures had comparable mechanical properties to PHB cast using chloroform. This acetic acid based method is environmentally friendly, cost efficient and allows more flexible processing conditions and broader ranges of polymer properties than traditional methods.

A Concept of Two-Stage-To-Orbit Reusable Launch Vehicle

NASA Astrophysics Data System (ADS)

Yang, Yong; Wang, Xiaojun; Tang, Yihua

2002-01-01

Reusable Launch Vehicle (RLV) has a capability of delivering a wide rang of payload to earth orbit with greater reliability, lower cost, more flexibility and operability than any of today's launch vehicles. It is the goal of future space transportation systems. Past experience on single stage to orbit (SSTO) RLVs, such as NASA's NASP project, which aims at developing an rocket-based combined-cycle (RBCC) airplane and X-33, which aims at developing a rocket RLV, indicates that SSTO RLV can not be realized in the next few years based on the state-of-the-art technologies. This paper presents a concept of all rocket two-stage-to-orbit (TSTO) reusable launch vehicle. The TSTO RLV comprises an orbiter and a booster stage. The orbiter is mounted on the top of the booster stage. The TSTO RLV takes off vertically. At the altitude about 50km the booster stage is separated from the orbiter, returns and lands by parachutes and airbags, or lands horizontally by means of its own propulsion system. The orbiter continues its ascent flight and delivers the payload into LEO orbit. After completing orbit mission, the orbiter will reenter into the atmosphere, automatically fly to the ground base and finally horizontally land on the runway. TSTO RLV has less technology difficulties and risk than SSTO, and maybe the practical approach to the RLV in the near future.

Education and Caste in India

ERIC Educational Resources Information Center

Chauhan, Chandra Pal Singh

2008-01-01

This paper analyses the policy of reservation for lower castes in India. This policy is similar to that of affirmative action in the United States. The paper provides a brief overview of the caste system and discusses the types of groups that are eligible for reservation, based on data from government reports. The stance of this paper is that…

Biological profiling of the ToxCast Phase II Chemical Library in Primary Human Cell Co-Culture Systems

EPA Science Inventory

The U.S. EPA’s ToxCast research project was developed to address the need for high-throughput testing of chemicals and a pathway-based approach to hazard screening. Phase I of ToxCast tested over 300 unique compounds (mostly pesticides and antimicrobials). With the addition of Ph...

20180312 - Profiling the ToxCast library with a pluripotent human (H9) embryonic stem cell assay (SOT)

EPA Science Inventory

The Stemina devTOX quickPredict platform (STM) is a human pluripotent H9 stem cell-based assay that predicts developmental toxicants. Using the STM model, we screened 1065 ToxCast chemicals and entered the data into the ToxCast data analysis pipeline. Model performance was 83.3% ...

Safety for Your Child: 6 Years

MedlinePlus

... the street without a grown-up. And Remember Car Safety Your child must now use a booster seat in the car. Always check to be sure that he or ... in the booster seat before you start the car. Your child should use a booster seat until ...

General view of a fully assembled Solid Rocket Booster sitting ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

General view of a fully assembled Solid Rocket Booster sitting atop the Mobile Launch Platform in the Vehicle Assembly Building at Kennedy Space Center - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

47 CFR 74.1232 - Eligibility and licensing requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1232 Eligibility and licensing requirements. (a... incurred by installing, repairing, or making adjustments to equipment. (f) An FM broadcast booster station... the booster station will retransmit, to serve areas within the protected contour of the primary...

47 CFR 74.635 - Unattended operation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... stations, and TV microwave booster stations may be operated unattended under the following conditions: (1... persons; (3) TV relay stations, TV STL stations, TV translator relay stations, and TV microwave booster..., an STL station (and any TV microwave booster station) associated with a TV broadcast station operated...

47 CFR 74.635 - Unattended operation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... stations, and TV microwave booster stations may be operated unattended under the following conditions: (1... persons; (3) TV relay stations, TV STL stations, TV translator relay stations, and TV microwave booster..., an STL station (and any TV microwave booster station) associated with a TV broadcast station operated...

Shuttle Boosters stacked in the VAB

NASA Image and Video Library

2007-01-04

Workers continue stacking the solid rocket boosters in highbay 1 inside Kennedy Space Center's Vehicle Assembly Building. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

47 CFR 74.1232 - Eligibility and licensing requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1232 Eligibility and licensing requirements. (a... incurred by installing, repairing, or making adjustments to equipment. (f) An FM broadcast booster station... the booster station will retransmit, to serve areas within the protected contour of the primary...

47 CFR 74.635 - Unattended operation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... stations, and TV microwave booster stations may be operated unattended under the following conditions: (1... persons; (3) TV relay stations, TV STL stations, TV translator relay stations, and TV microwave booster..., an STL station (and any TV microwave booster station) associated with a TV broadcast station operated...

47 CFR 74.635 - Unattended operation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... stations, and TV microwave booster stations may be operated unattended under the following conditions: (1... persons; (3) TV relay stations, TV STL stations, TV translator relay stations, and TV microwave booster..., an STL station (and any TV microwave booster station) associated with a TV broadcast station operated...

47 CFR 74.1232 - Eligibility and licensing requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1232 Eligibility and licensing requirements. (a... incurred by installing, repairing, or making adjustments to equipment. (f) An FM broadcast booster station... the booster station will retransmit, to serve areas within the protected contour of the primary...

47 CFR 74.1250 - Transmitters and associated equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1250 Transmitters and associated equipment. (a) FM translator and booster transmitting apparatus, and exciters employed to provide a locally generated and modulated input signal to translator and booster equipment, used by stations authorized under the provisions...

47 CFR 74.1250 - Transmitters and associated equipment.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1250 Transmitters and associated equipment. (a) FM translator and booster transmitting apparatus, and exciters employed to provide a locally generated and modulated input signal to translator and booster equipment, used by stations authorized under the provisions...

47 CFR 74.1250 - Transmitters and associated equipment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1250 Transmitters and associated equipment. (a) FM translator and booster transmitting apparatus, and exciters employed to provide a locally generated and modulated input signal to translator and booster equipment, used by stations authorized under the provisions...

47 CFR 74.1250 - Transmitters and associated equipment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1250 Transmitters and associated equipment. (a) FM translator and booster transmitting apparatus, and exciters employed to provide a locally generated and modulated input signal to translator and booster equipment, used by stations authorized under the provisions...

Utilizing ToxCast Data and Lifestage Physiologically-Based Pharmacokinetic (PBPK) models to Drive Adverse Outcome Pathways (AOPs)-Based Margin of Exposures (ABME) to Chemicals.

EPA Science Inventory

Utilizing ToxCast Data and Lifestage Physiologically-Based Pharmacokinetic (PBPK) models to Drive Adverse Outcome Pathways (AOPs)-Based Margin of Exposures (ABME) to Chemicals. Hisham A. El-Masri1, Nicole C. Klienstreur2, Linda Adams1, Tamara Tal1, Stephanie Padilla1, Kristin I...

Design and prototype tests of a large-aperture 37-53 MHz ferrite-tuned booster synchrotron cavity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mark S. Champion et al.

The Booster synchrotron at Fermilab employs eighteen 37-53 MHz ferrite-tuned double-gap coaxial radiofrequency cavities for acceleration of protons from 400 MeV to 8 GeV. The cavities have an aperture of 2.25 inches and operate at 55 kV per cavity. Future high duty factor operation of the Booster will be problematic due to unavoidable beam loss at the cavities resulting in excessive activation. The power amplifiers, high maintenance items, are mounted directly to the cavities in the tunnel. A proposed replacement for the Booster, the Proton Driver, will utilize the Booster radiofrequency cavities and requires not only a larger aperture, butmore » also higher voltage. A research and development program is underway at Fermilab to modify the Booster cavities to provide a 5-inch aperture and a 20% voltage increase. A prototype has been constructed and high power tests have bee completed. The cavity design and test results is presented.« less

A randomized clinical trial on the effectiveness of a reintegration training program versus booster sessions after short-term inpatient psychotherapy.

PubMed

Thunnissen, Moniek; Duivenvoorden, Hugo; Busschbach, Jan; Hakkaart-van Roijen, Leona; van Tilburg, Willem; Verheul, Roel; Trijsburg, Wim

2008-10-01

Although several studies show symptomatic improvements in patients with personality disorders after short-term inpatient psychotherapy, reintegration remains difficult. In this study the effectiveness of a specifically designed reintegration training program is investigated. One hundred twenty-eight patients were randomized to either a reintegration training program aimed at improving general functioning and work resumption, or booster sessions. Outcome measures used were symptom level, work status, absence from and impediments at work. The results showed that compliance in the booster session group was significantly better than in the reintegration training program. The percentage of persons with a paid job increased during the booster sessions from 64 to 87%, but not during the reintegration training (76%). There were no differences in the other outcome measures. We concluded that reintegration training was not more (cost)-effective than booster sessions. Our hypothesis is that continuity of care (same therapists and program) explains the favorable results of the booster sessions.

ION BEAM POLARIZATION DYNAMICS IN THE 8 GEV BOOSTER OF THE JLEIC PROJECT AT JLAB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kondratenko, A. M.; Kondratenko, M. A.; Morozov, Vasiliy

2016-05-01

In the Jefferson Lab’s Electron-Ion Collider (JLEIC) project, an injector of polarized ions into the collider ring is a superconducting 8 GeV booster. Both figure-8 and racetrack booster versions were considered. Our analysis showed that the figure-8 ring configuration allows one to preserve the polarization of any ion species during beam acceleration using only small longitudinal field with an integral less than 0.5 Tm. In the racetrack booster, to pre-serve the polarization of ions with the exception of deu-terons, it suffices to use a solenoidal Siberian snake with a maximum field integral of 30 Tm. To preserve deuteron polarization, wemore » propose to use arc magnets for the race-track booster structure with a field ramp rate of the order of 1 T/s. We calculate deuteron and proton beam polari-zations in both the figure-8 and racetrack boosters includ-ing alignment errors of their magnetic elements using the Zgoubi code.« less

Advanced Space Transportation Program (ASTP)

NASA Image and Video Library

2000-04-03

This is a computer generated image of a Shuttle launch utilizing 2nd generation Reusable Launch Vehicle (RLV) flyback boosters, a futuristic concept that is currently undergoing study by NASA's Space Launch Initiative (SLI) Propulsion Office, managed by the Marshall Space Fight Center in Huntsville, Alabama, working in conjunction with the Agency's Glenn Research Center in Cleveland, Ohio. Currently, after providing thrust to the Space Shuttle, the solid rocket boosters are parachuted into the sea and are retrieved for reuse. The SLI is considering vehicle concepts that would fly first-stage boosters back to a designated landing site after separation from the orbital vehicle. These flyback boosters would be powered by several jet engines integrated into the booster capable of providing over 100,000 pounds of thrust. The study will determine the requirements for the engines, identify risk mitigation activities, and identify costs associated with risk mitigation and jet engine development and production, as well as determine candidate jet engine options to pursue for the flyback booster.

Combating pertussis resurgence: One booster vaccination schedule does not fit all.

PubMed

Riolo, Maria A; Rohani, Pejman

2015-02-03

Pertussis has reemerged as a major public health concern in many countries where it was once considered well controlled. Although the mechanisms responsible for continued pertussis circulation and resurgence remain elusive and contentious, many countries have nevertheless recommended booster vaccinations, the timing and number of which vary widely. Here, using a stochastic, age-stratified transmission model, we searched for cost-effective booster vaccination strategies using a genetic algorithm. We did so assuming four hypothesized mechanisms underpinning contemporary pertussis epidemiology: (I) insufficient coverage, (II) frequent primary vaccine failure, (III) waning of vaccine-derived protection, and (IV) vaccine "leakiness." For scenarios I-IV, successful booster strategies were identified and varied considerably by mechanism. Especially notable is the inability of booster schedules to alleviate resurgence when vaccines are leaky. Critically, our findings argue that the ultimate effectiveness of vaccine booster schedules will likely depend on correctly pinpointing the causes of resurgence, with misdiagnosis of the problem epidemiologically ineffective and economically costly.

Fuze for explosive magnetohydrodynamic generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webb, G.

1976-12-23

An apparatus is examined by which high explosive charges are propelled into and detonated at the center of an MHD-X generator. The high explosive charge units are engaged and propelled by a reciprocating ram device. Detonating in each instance is achieved by striking with a firing pin a detonator charge that is in register with a booster charge, the booster charge being in detonating communication with the high explosive charge. Various safety requirements are satisfied by a spring loaded slider operating in a channel transverse and adjacent to the booster charge. The slide retains the detonator charge out of registermore » with the booster charge until a safety pin that holds the slider in place is pulled by a lanyard attached between the reciprocating ram and the safety pin. Removal of the safety pin permits the detonator charge to slide into alignment with the booster charge. Firing pin actuation is initiated by the slider at the instant the detonator charge and the booster charge come into register.« less

Liquid Rocket Booster (LRB) for the Space Transportation System (STS) systems study. Appendix F: Performance and trajectory for ALS/LRB launch vehicles

NASA Technical Reports Server (NTRS)

1989-01-01

By simply combining two baseline pump-fed LOX/RP-1 Liquid Rocket Boosters (LRBs) with the Denver core, a launch vehicle (Option 1 Advanced Launch System (ALS)) is obtained that can perform both the 28.5 deg (ALS) mission and the polar orbit ALS mission. The Option 2 LRB was obtained by finding the optimum LOX/LH2 engine for the STS/LRB reference mission (70.5 K lb payload). Then this engine and booster were used to estimate ALS payload for the 28.5 deg inclination ALS mission. Previous studies indicated that the optimum number of STS/LRB engines is four. When the engine/booster sizing was performed, each engine had 478 K lb sea level thrust and the booster carried 625,000 lb of useable propellant. Two of these LRBs combined with the Denver core provided a launch vehicle that meets the payload requirements for both the ALS and STS reference missions. The Option 3 LRB uses common engines for the cores and boosters. The booster engines do not have the nozzle extension. These engines were sized as common ALS engines. An ALS launch vehicle that has six core engines and five engines per booster provides 109,100 lb payload for the 28.5 deg mission. Each of these LOX/LH2 LRBs carries 714,100 lb of useable propellant. It is estimated that the STS/LRB reference mission payload would be 75,900 lb.

Distal limb cast sores in horses: risk factors and early detection using thermography.

PubMed

Levet, T; Martens, A; Devisscher, L; Duchateau, L; Bogaert, L; Vlaminck, L

2009-01-01

There is a lack of evidence-based data on the prevalence, outcome and risk factors of distal limb cast sores, and no objective tool has been described for the early detection of cast sores. To investigate the prevalence, location, outcome and risk factors of cast sores after application of a distal limb cast and to determine whether static thermography of the cast is a valuable tool for the assessment of sores. A prospective study was conducted on horses treated with a distal limb cast. At each cast removal, cast sores were graded as superficial sores (SS), deep dermal sores (DS) or full thickness skin ulcerations (FS). In several cases, a thermographic evaluation of the cast was performed immediately prior to removal and differences in temperature (AT) between the coolest point of the cast and 2 cast regions predisposed for sore development (dorsoproximal mc/mtIII and palmar/plantar fetlock) were calculated. Mean +/- s.d. total casting time of 70 horses was 31 +/- 18 days. Overall, 57 legs (81%) developed at least SS. Twenty-four legs (34%) ultimately developed DS and one horse had an FS. Multivariable analysis showed that the severity of sores was positively associated with increasing age (OR: 1.111, P = 0.028), a normal (vs. swollen) limb (OR: 3387, P = 0.023) and an increase in total casting time (OR per week: 1.363, P = 0.002). The thermographic evaluation (35 casts) revealed that the severity of sores was positively associated with increasing deltaT (OR: 2.100, P = 0.0005). The optimal cut-off values for the presence of SS and DS were set at, respectively, deltaT = 23 and 43 degrees C. Distal limb cast is a safe coaptation technique with increasing risk of developing sores with time. Thermography is a valuable and rapid clinical tool to monitor the development of cast sores.

Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot transonic wind tunnel, volume 2

NASA Technical Reports Server (NTRS)

Marroquin, J.; Lemoine, P.

1992-01-01

An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e., top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot Transonic wind tunnel (IA613A), volume 1

NASA Technical Reports Server (NTRS)

Marroquin, J.; Lemoine, P.

1992-01-01

An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e. top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

Fracture behavior of metal-ceramic fixed dental prostheses with frameworks from cast or a newly developed sintered cobalt-chromium alloy.

PubMed

Krug, Klaus-Peter; Knauber, Andreas W; Nothdurft, Frank P

2015-03-01

The aim of this study was to investigate the fracture behavior of metal-ceramic bridges with frameworks from cobalt-chromium-molybdenum (CoCrMo), which are manufactured using conventional casting or a new computer-aided design/computer-aided manufacturing (CAD/CAM) milling and sintering technique. A total of 32 metal-ceramic fixed dental prostheses (FDPs), which are based on a nonprecious metal framework, was produced using a conventional casting process (n = 16) or a new CAD/CAM milling and sintering process (n = 16). Eight unveneered frameworks were manufactured using each of the techniques. After thermal and mechanical aging of half of the restorations, all samples were subjected to a static loading test in a universal testing machine, in which acoustic emission monitoring was performed. Three different critical forces were revealed: the fracture force (F max), the force at the first reduction in force (F decr1), and the force at the critical acoustic event (F acoust1). With the exception of the veneered restorations with cast or sintered metal frameworks without artificial aging, which presented a statistically significant but slightly different F max, no statistically significant differences between cast and CAD/CAM sintered and milled FDPs were detected. Thermal and mechanical loading did not significantly affect the resulting forces. Cast and CAD/CAM milled and sintered metal-ceramic bridges were determined to be comparable with respect to the fracture behavior. FDPs based on CAD/CAM milled and sintered frameworks may be an applicable and less technique-sensitive alternative to frameworks that are based on conventionally cast frameworks.

47 CFR 74.750 - Transmission system facilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

47 CFR 74.750 - Transmission system facilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

Shuttle Boosters stacked in the VAB

NASA Image and Video Library

2007-01-04

Workers continue stacking the twin solid rocket boosters in highbay 1 inside Kennedy Space Center's Vehicle Assembly Building. The solid rocket boosters are being prepared for NASA's next Space Shuttle launch, mission STS-117. The mission is scheduled to launch aboard Atlantis no earlier than March 16, 2007.

47 CFR 74.1201 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... FM Broadcast Booster Stations § 74.1201 Definitions. (a) FM translator. A station in the broadcasting... retransmitted by an FM broadcast translator station or an FM broadcast booster station. (e) AM or FM radio... indicates otherwise. (f) FM broadcast booster station. A station in the broadcasting service operated for...

47 CFR 74.1201 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... FM Broadcast Booster Stations § 74.1201 Definitions. (a) FM translator. A station in the broadcasting... retransmitted by an FM broadcast translator station or an FM broadcast booster station. (e) AM or FM radio... indicates otherwise. (f) FM broadcast booster station. A station in the broadcasting service operated for...

47 CFR 74.750 - Transmission system facilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

47 CFR 74.1201 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... FM Broadcast Booster Stations § 74.1201 Definitions. (a) FM translator. A station in the broadcasting... retransmitted by an FM broadcast translator station or an FM broadcast booster station. (e) AM or FM radio... indicates otherwise. (f) FM broadcast booster station. A station in the broadcasting service operated for...

47 CFR 74.1201 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FM Broadcast Booster Stations § 74.1201 Definitions. (a) FM translator. A station in the broadcasting... retransmitted by an FM broadcast translator station or an FM broadcast booster station. (e) AM or FM radio... indicates otherwise. (f) FM broadcast booster station. A station in the broadcasting service operated for...

Interventions for promoting booster seat use in four to eight year olds traveling in motor vehicles.

PubMed

Ehiri, J E; Ejere, H O D; Magnussen, L; Emusu, D; King, W; Osberg, J S

2006-01-25

Public health and traffic safety agencies recommend use of booster seats in motor vehicles for children aged four to eight years, and various interventions have been implemented to increase their use by individuals who transport children in motor vehicles. There is little evidence regarding the effectiveness of these interventions, hence the need to examine what works and what does not. To assess the effectiveness of interventions intended to increase acquisition and use of booster seats in motor vehicles among four to eight year olds. We searched the Cochrane Injuries Group's Specialized Register, the Cochrane Central Register of Controlled Trials, MEDLINE (January 1966 to April 2005), EMBASE (1980 to April 2005), LILACS, Transport Research Databases (1988 to April 2005), Australian Transport Index (1976 to April 2005), additional databases and reference lists of relevant articles. We also contacted experts in the field. We included randomized and controlled before-and-after trials that investigated the effects of interventions to promote booster seat use. Two authors independently assessed trial quality and extracted data. Study authors were contacted for additional information. Five studies involving 3,070 individuals met the criteria for inclusion in the meta-analysis. All interventions for promoting use of booster seats among 4 to 8 year olds demonstrated a positive effect (relative risk (RR) 1.43; 95% confidence intervals (CI) 1.05 to 1.96). Incentives combined with education demonstrated a beneficial effect (RR 1.32, 95% CI 1.12 to 1.55; n = 1,898). Distribution of free booster seats combined with education also had a beneficial effect (RR 2.34; 95% CI 1.50 to 3.63; n = 380) as did education-only interventions (RR 1.32; 95% CI 1.16 to 1.49; n = 563). One study which evaluated enforcement of booster seat law met the criteria for inclusion in the meta-analysis, but demonstrated no marked beneficial effect. Available evidence suggests that interventions to increase use of booster seats among children age four to eight years are effective. Combining incentives (booster seat discount coupons or gift certificates) or distribution of free booster seats with education demonstrated marked beneficial outcomes for acquisition and use of booster seats for four to eight year olds. There is some evidence of beneficial effect of legislation on acquisition and use of booster seats but this was mainly from uncontrolled before-and-after studies, which did not meet the criteria for inclusion in the meta-analysis.

Beryllium and titanium cost-adjustment report

NASA Astrophysics Data System (ADS)

Owen, John; Ulph, Eric, Sr.

1991-09-01

This report summarizes cost adjustment factors for beryllium (Be, S200) and titanium (Ti, 6Al-4V) that were derived relative to aluminum (Al, 7075-T6). Aluminum is traditionally the material upon which many of the Cost Analysis Office, Missile Division cost estimating relationships (CERs) are based. The adjustment factors address both research and development and production (Q > 100) quantities. In addition, the factors derived include optical elements, normal structure, and structure with special requirements for minimal microcreep, such as sensor assembly parts and supporting components. Since booster cost per payload pound is an even larger factor in total missile launch costs than was initially presumed, the primary cost driver for all materials compared was the missiles' booster cost per payload pound for both R&D and production quantities. Al and Ti are 1.5 and 2.4 times more dense, respectively, than Be, and the cost to lift the heavier materials results in greater booster expense. In addition, Al and Ti must be 2.1 and 2.8, respectively, times the weight of a Be component to provide equivalent stiffness, based on the example component addressed in the report. These factors also increase booster costs. After review of the relative factors cited above, especially the lower costs for Be when stiffness and booster costs are taken into consideration, affordability becomes an important issue. When this study was initiated, both government and contractor engineers said that Be was the material to be used as a last resort because of its prohibitive cost and extreme toxicity. Although the initial price of Be may lead one to believe that any Be product would be extremely expensive, the total cost of Be used for space applications is actually competitive with or less costly than either Al or Ti. Also, the Be toxicity problem has turned out to be a non-issue for purchasers of finished Be components since no machining or grinding operations are required on the finished components. Several new costing techniques are developed which provide quantitative measures of the cost of material stiffness, costs related to payload weight, and costs associated with the relative temperature stability of different materials. In addition, use is made of the Design/Cost Trade Model developed by Applied Research, Inc., to determine the booster cost differential relative to changes in payload weight, and a mirror fabrication cost model, developed by OCA Applied Optics, was used for mirror costing. This report is a summary of an extensive study done by the U.S. Army Strategic Defense Command, Huntsville, Alabama.

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – Workers prepare to lift the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is lifted from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – A worker surveys the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, secured in a transportation hardware cradle, that he delivered to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is lowered onto a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – Workers secure the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, onto a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, and its transportation hardware cradle roll into the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 1st Stage Booster Preps

NASA Image and Video Library

2014-03-21

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, rests on a transportation cradle in the Horizontal Integration Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 1st Stage Booster Preps

NASA Image and Video Library

2014-03-21

VANDENBERG AIR FORCE BASE, Calif. – A worker in the Horizontal Integration Facility inspects the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, before its move to Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – Workers steady the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, as it is lifted from its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-19

VANDENBERG AIR FORCE BASE, Calif. – Preparations are underway to offload the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, into the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, rests on a transportation hardware cradle in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California awaiting installation on the pad. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 1st Stage Booster Preps

NASA Image and Video Library

2014-03-21

VANDENBERG AIR FORCE BASE, Calif. – A tethered worker in the Horizontal Integration Facility prepares the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, for its move to Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Offload

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, is suspended above its transportation trailer in the Building 836 hangar at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – The Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, secured in a transportation hardware cradle, is towed to the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

OCO-2 Booster Arrival

NASA Image and Video Library

2014-03-20

VANDENBERG AIR FORCE BASE, Calif. – A worker maneuvers the transporter towing the Delta first-stage booster for NASA's Orbiting Carbon Observatory-2 mission, or OCO-2, at the Horizontal Processing Facility at Space Launch Complex 2 on Vandenberg Air Force Base in California. OCO-2 is scheduled to launch aboard a United Launch Alliance Delta II rocket in July. The observatory will collect precise global measurements of carbon dioxide in the Earth's atmosphere and provide scientists with a better idea of the chemical compound's impacts on climate change. Scientists will analyze this data to improve our understanding of the natural processes and human activities that regulate the abundance and distribution of this important atmospheric gas. To learn more about OCO-2, visit http://oco.jpl.nasa.gov. Photo credit: NASA/Randy Beaudoin

A Comparative Evaluation of the Effect of Double Casting Technique Using Functionally Generated Path and Conventional Single Casting with Respect to Functional Articulation, Patient Satisfaction and Chair Side Time, in Single Unit Molar Teeth: An In Vivo Study.

PubMed

Memon, Sarfaraz

2014-12-01

A stable centric occlusal position that shows no evidence of occlusal disease should not be altered. Confirmative restorative dentistry deals with making restorations that are in harmony with existing jaw relations. Conventional techniques for construction have been unsuccessful in producing a prosthesis that can be inserted without minor intraoral occlusal adjustment. This study was conducted to evaluate the benefits of the double casting technique with FGP over the conventional casting technique. Ten patients with root canal treated maxillary molar were selected for the fabrication of metal crown. Two techniques, one involving the conventional fabrication and other using functionally generated path with double casting were used to fabricate the prosthesis. A comparison based on various parameters which was done between the two techniques. The change in the height of castings for the double casting group was less compared to the conventional group and was highly statistically significant (P < 0.001). The time taken for occlusal correction was significantly lower in double casting group than the conventional group (P < 0.001). The patient satisfaction (before occlusal correction) indicated better satisfaction for double casting group compared to conventional (P < 0.01). The functionally generated path with double casting technique resulted in castings which had better dimensional accuracy, less occlusal correction and better patient satisfaction compared to the conventional castings.

Evaluation of marginal gap of Ni-Cr copings made with conventional and accelerated casting techniques.

PubMed

Tannamala, Pavan Kumar; Azhagarasan, Nagarasampatti Sivaprakasam; Shankar, K Chitra

2013-01-01

Conventional casting techniques following the manufacturers' recommendations are time consuming. Accelerated casting techniques have been reported, but their accuracy with base metal alloys has not been adequately studied. We measured the vertical marginal gap of nickel-chromium copings made by conventional and accelerated casting techniques and determined the clinical acceptability of the cast copings in this study. Experimental design, in vitro study, lab settings. Ten copings each were cast by conventional and accelerated casting techniques. All copings were identical, only their mold preparation schedules differed. Microscopic measurements were recorded at ×80 magnification on the perpendicular to the axial wall at four predetermined sites. The marginal gap values were evaluated by paired t test. The mean marginal gap by conventional technique (34.02 μm) is approximately 10 μm lesser than that of accelerated casting technique (44.62 μm). As the P value is less than 0.0001, there is highly significant difference between the two techniques with regard to vertical marginal gap. The accelerated casting technique is time saving and the marginal gap measured was within the clinically acceptable limits and could be an alternative to time-consuming conventional techniques.

NASA's NB-52B carrier aircraft rolls down a taxiway with the X-43A hypersonic research aircraft and its modified Pegasus® booster rocket attached to a pylon under its right wing.

NASA Image and Video Library

2001-03-15

As part of a combined systems test conducted by NASA Dryden Flight Research Center, NASA's NB-52B carrier aircraft rolls down a taxiway at Edwards Air Force Base with the X-43A hypersonic research aircraft and its modified Pegasus® booster rocket attached to a pylon under its right wing. The taxi test was one of the last major milestones in the Hyper-X research program before the first X-43A flight. The X-43A flights will be the first actual flight tests of an aircraft powered by a revolutionary supersonic-combustion ramjet ("scramjet") engine capable of operating at hypersonic speeds (above Mach 5, or five times the speed of sound). The 12-foot, unpiloted research vehicle was developed and built by MicroCraft Inc., Tullahoma, Tenn., under NASA contract. The booster was built by Orbital Sciences Corp., Dulles, Va. After being air-launched from NASA's venerable NB-52 mothership, the booster will accelerate the X-43A to test speed and altitude. The X-43A will then separate from the rocket and fly a pre-programmed trajectory, conducting aerodynamic and propulsion experiments until it descends into the Pacific Ocean. Three research flights are planned, two at Mach 7 and one at Mach 10.

Hybrid Propulsion Technology Program, phase 1. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1989-01-01

The study program was contracted to evaluate concepts of hybrid propulsion, select the most optimum, and prepare a conceptual design package. Further, this study required preparation of a technology definition package to identify hybrid propulsion enabling technologies and planning to acquire that technology in Phase 2 and demonstrate that technology in Phase 3. Researchers evaluated two design philosophies for Hybrid Rocket Booster (HRB) selection. The first is an ASRM modified hybrid wherein as many components/designs as possible were used from the present Advanced Solid Rocket Motor (ASRM) design. The second was an entirely new hybrid optimized booster using ASRM criteria as a point of departure, i.e., diameter, thrust time curve, launch facilities, and external tank attach points. Researchers selected the new design based on the logic of optimizing a hybrid booster to provide NASA with a next generation vehicle in lieu of an interim advancement over the ASRM. The enabling technologies for hybrid propulsion are applicable to either and vehicle design may be selected at a downstream point (Phase 3) at NASA's discretion. The completion of these studies resulted in ranking the various concepts of boosters from the RSRM to a turbopump fed (TF) hybrid. The scoring resulting from the Figure of Merit (FOM) scoring system clearly shows a natural growth path where the turbopump fed solid liquid staged combustion hybrid provides maximized payload and the highest safety, reliability, and low life cycle costing.

Developing ShakeCast statistical fragility analysis framework for rapid post-earthquake assessment

USGS Publications Warehouse

Lin, K.-W.; Wald, D.J.

2012-01-01

When an earthquake occurs, the U. S. Geological Survey (USGS) ShakeMap estimates the extent of potentially damaging shaking and provides overall information regarding the affected areas. The USGS ShakeCast system is a freely-available, post-earthquake situational awareness application that automatically retrieves earthquake shaking data from ShakeMap, compares intensity measures against users’ facilities, sends notifications of potential damage to responsible parties, and generates facility damage assessment maps and other web-based products for emergency managers and responders. We describe notable improvements of the ShakeMap and the ShakeCast applications. We present a design for comprehensive fragility implementation, integrating spatially-varying ground-motion uncertainties into fragility curves for ShakeCast operations. For each facility, an overall inspection priority (or damage assessment) is assigned on the basis of combined component-based fragility curves using pre-defined logic. While regular ShakeCast users receive overall inspection priority designations for each facility, engineers can access the full fragility analyses for further evaluation.

Microstructure and Properties of Cobalt-and Zinc-Containing Magnetic Magnesium Alloys Processed by High-Pressure Die Casting

NASA Astrophysics Data System (ADS)

Klose, Christian; Demminger, Christian; Maier, Hans Jürgen

The inherent magnetic properties of lightweight alloys based on magnesium and cobalt offer a novel way in order to measure mechanical loads throughout the entire structural component using the magnetoelastic effect. Because the solubility of cobalt in the magnesium matrix is negligible, the magnetic properties mainly originate from Co-rich precipitates. Thus, the size and distribution of Co-containing phases within the alloy's microstructure wields a major influence on the amplitude of the load-sensitive properties which can be measured by employing the harmonic analysis of eddy-current signals. In this study, Mg-Co-based alloys are produced by several casting methods which allow the application of different cooling rates, e.g. gravity die casting and high-pressure die casting. The differences between the manufactured alloys' micro- and phase structures are compared depending on the applied cooling rate and the superior magnetic and mechanical properties of the high-pressure die cast material are demonstrated.

Evaluation of Uranium-235 Measurement Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaspar, Tiffany C.; Lavender, Curt A.; Dibert, Mark W.

2017-05-23

Monolithic U-Mo fuel plates are rolled to final fuel element form from the original cast ingot, and thus any inhomogeneities in 235U distribution present in the cast ingot are maintained, and potentially exaggerated, in the final fuel foil. The tolerance for inhomogeneities in the 235U concentration in the final fuel element foil is very low. A near-real-time, nondestructive technique to evaluate the 235U distribution in the cast ingot is required in order to provide feedback to the casting process. Based on the technical analysis herein, gamma spectroscopy has been recommended to provide a near-real-time measure of the 235U distribution inmore » U-Mo cast plates.« less

Long-term oxidation of candidate cast iron and stainless steel exhaust system alloys from 650 to 800 °C in air with water vapor

DOE PAGES

Brady, Michael P.; Muralidharan, Govindarajan; Leonard, Donovan .; ...

2014-08-29

Here, the oxidation behavior of SiMo cast iron, Ni-resist D 5S cast iron, cast chromia-forming austenitic stainless steels of varying Cr/Ni content based on CF8C plus, HK, and HP, and a developmental cast alumina-forming austenitic (AFA) stainless steel of interest for diesel exhaust system components were studied for up to 5000 h at 650-800 °C in air with 10% H 2O. At 650 °C, the Ni-resist D5S exhibited moderately better oxidation resistance than did the SiMo cast iron. However, the D5S suffered from oxide scale spallation issues at 700 °C and higher, whereas the oxide scales formed on SiMo castmore » iron remained adherent from 700-800 °C despite oxide scales hundreds of microns thick. The oxidation of the SiMo cast iron exhibited unusual temperature dependence, with periods of slower oxidation kinetics at 750-800 °C compared to 650-700 °C due to continuous silica-rich scale formation at the higher temperatures. The oxidation of the cast chromia-forming austenitics trended with the level of Cr and Ni additions, with small mass losses consistent with Cr oxy-hydroxide volatilization processes for the higher 25Cr/25-35Ni HK and HP type alloys, and transition to rapid Fe-base oxide formation and scale spallation in the lower 19Cr/12Ni CF8C plus type alloy. In contrast, small positive mass changes consistent with protective alumina scale formation were observed for the cast AFA alloy under all conditions studied. Implications of these findings for diesel exhaust system components are discussed.« less

Study of solid rocket motor for a space shuttle booster

NASA Technical Reports Server (NTRS)

1972-01-01

The study of solid rocket motors for a space shuttle booster was directed toward definition of a parallel-burn shuttle booster using two 156-in.-dia solid rocket motors. The study effort was organized into the following major task areas: system studies, preliminary design, program planning, and program costing.

47 CFR 74.761 - Frequency tolerance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Booster Stations § 74.761 Frequency tolerance. The licensee of a low power TV, TV translator, or TV booster station shall maintain the transmitter output frequencies as set forth below. The frequency... channel carrier frequency if the low power TV, TV translator, or TV booster station is authorized with a...

47 CFR 74.1261 - Frequency tolerance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... FM Broadcast Booster Stations § 74.1261 Frequency tolerance. (a) The licensee of an FM translator or booster station with an authorized transmitter power output of 10 watts or less shall maintain the center... an FM translator or booster station with an authorized transmitter power output greater than 10 watts...

47 CFR 74.761 - Frequency tolerance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Booster Stations § 74.761 Frequency tolerance. The licensee of a low power TV, TV translator, or TV booster station shall maintain the transmitter output frequencies as set forth below. The frequency... channel carrier frequency if the low power TV, TV translator, or TV booster station is authorized with a...

47 CFR 74.1231 - Purpose and permissible service.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Translator Stations and FM Broadcast Booster Stations § 74.1231 Purpose and permissible service. (a) FM... facilities to receive the signal that is being rebroadcast. An FM booster station or a noncommercial... used to deliver signals to FM translator and booster stations on a secondary basis only. Such use shall...

47 CFR 27.1236 - Self-transitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... station or booster serving each EBS receive site entitled to protection, including: (i) The make and model of the antenna for that main station or booster, along with the radiation pattern if it is not... building or antenna supporting structure on which the main station or booster transmission antenna is...