Sample records for based microanalytical facility

  1. Examining the Level of Convergence among Self-Regulated Learning Microanalytic Processes, Achievement, and a Self-Report Questionnaire

    ERIC Educational Resources Information Center

    Cleary, Timothy J.; Callan, Gregory L.; Malatesta, Jaime; Adams, Tanya

    2015-01-01

    This study examined the convergent and predictive validity of self-regulated learning (SRL) microanalytic measures. Specifically, theoretically based relations among a set of self-reflection processes, self-efficacy, and achievement were examined as was the level of convergence between a microanalytic strategy measure and a SRL self-report…

  2. Compact electrochemical sensor system and method for field testing for metals in saliva or other fluids

    DOEpatents

    Lin, Yuehe; Bennett, Wendy D.; Timchalk, Charles; Thrall, Karla D.

    2004-03-02

    Microanalytical systems based on a microfluidics/electrochemical detection scheme are described. Individual modules, such as microfabricated piezoelectrically actuated pumps and a microelectrochemical cell were integrated onto portable platforms. This allowed rapid change-out and repair of individual components by incorporating "plug and play" concepts now standard in PC's. Different integration schemes were used for construction of the microanalytical systems based on microfluidics/electrochemical detection. In one scheme, all individual modules were integrated in the surface of the standard microfluidic platform based on a plug-and-play design. Microelectrochemical flow cell which integrated three electrodes based on a wall-jet design was fabricated on polymer substrate. The microelectrochemical flow cell was then plugged directly into the microfluidic platform. Another integration scheme was based on a multilayer lamination method utilizing stacking modules with different functionality to achieve a compact microanalytical device. Application of the microanalytical system for detection of lead in, for example, river water and saliva samples using stripping voltammetry is described.

  3. Development of Aspen: A microanalytic simulation model of the US economy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pryor, R.J.; Basu, N.; Quint, T.

    1996-02-01

    This report describes the development of an agent-based microanalytic simulation model of the US economy. The microsimulation model capitalizes on recent technological advances in evolutionary learning and parallel computing. Results are reported for a test problem that was run using the model. The test results demonstrate the model`s ability to predict business-like cycles in an economy where prices and inventories are allowed to vary. Since most economic forecasting models have difficulty predicting any kind of cyclic behavior. These results show the potential of microanalytic simulation models to improve economic policy analysis and to provide new insights into underlying economic principles.more » Work already has begun on a more detailed model.« less

  4. Cosmic Dust Collection Facility: Scientific objectives and programmatic relations

    NASA Technical Reports Server (NTRS)

    Hoerz, Fred (Editor); Brownlee, D. E.; Bunch, T. E.; Grounds, D.; Grun, E.; Rummel, Y.; Quaide, W. L.; Walker, R. M.

    1990-01-01

    The science objectives are summarized for the Cosmic Dust Collection Facility (CDCF) on Space Station Freedom and these objectives are related to ongoing science programs and mission planning within NASA. The purpose is to illustrate the potential of the CDCF project within the broad context of early solar system sciences that emphasize the study of primitive objects in state-of-the-art analytical and experimental laboratories on Earth. Current knowledge about the sources of cosmic dust and their associated orbital dynamics is examined, and the results are reviewed of modern microanalytical investigations of extraterrestrial dust particles collected on Earth. Major areas of scientific inquiry and uncertainty are identified and it is shown how CDCF will contribute to their solution. General facility and instrument concepts that need to be pursued are introduced, and the major development tasks that are needed to attain the scientific objectives of the CDCF project are identified.

  5. Microanalytic Coding versus Global Rating of Maternal Parenting Behaviour

    ERIC Educational Resources Information Center

    Morawska, Alina; Basha, Allison; Adamson, Michelle; Winter, Leanne

    2015-01-01

    This study examined the relationship between microanalytic coding and global rating systems when coding maternal parenting behaviour in two contexts. Observational data from 55 mother--child interactions with two- to four-year-old children, in either a mealtime (clinic; N?=?20 or control; N?=?20) or a playtime context (community; N?=?15), were…

  6. Trace-Based Microanalytic Measurement of Self-Regulated Learning Processes

    ERIC Educational Resources Information Center

    Siadaty, Melody; Gaševic, Dragan; Hatala, Marek

    2016-01-01

    To keep pace with today's rapidly growing knowledge-driven society, productive self-regulation of one's learning processes are essential. We introduce and discuss a trace-based measurement protocol to measure the effects of scaffolding interventions on self-regulated learning (SRL) processes. It guides tracing of learners' actions in a learning…

  7. Negotiating Story Entry: A Micro-Analytic Study of Storytelling Projection in English and Japanese

    ERIC Educational Resources Information Center

    Yasui, Eiko

    2011-01-01

    This dissertation offers a micro-analytic study of the use of language and body during storytelling in American English and Japanese conversations. Specifically, I focus on its beginning and explore how a story is "projected." A beginning of an action or activity is where an incipient speaker negotiates the floor with co-participants; they…

  8. Using Microanalytical Simulation Methods in Educational Evaluation: An Exploratory Study

    ERIC Educational Resources Information Center

    Sondergeld, Toni A.; Beltyukova, Svetlana A.; Fox, Christine M.; Stone, Gregory E.

    2012-01-01

    Scientifically based research used to inform evidence based school reform efforts has been required by the federal government in order to receive grant funding since the reenactment of No Child Left Behind (2002). Educational evaluators are thus faced with the challenge to use rigorous research designs to establish causal relationships. However,…

  9. How Well Do Microanalytic Measures of Academic Self-Regulation Predict Teacher Ratings of Student Self-Regulated Learning in Science?

    ERIC Educational Resources Information Center

    DiBenedetto, Maria K.

    2009-01-01

    The purpose of the current investigation was to establish the validity of microanalytic measures used to assess students' self-regulation of an academic science task, not only in terms of immediate achievement, but also in terms of a well-established "person" measure of self-regulated learning. Person measures are designed to capture enduring…

  10. Ring-oven based preconcentration technique for microanalysis: simultaneous determination of Na, Fe, and Cu in fuel ethanol by laser induced breakdown spectroscopy.

    PubMed

    Cortez, Juliana; Pasquini, Celio

    2013-02-05

    The ring-oven technique, originally applied for classical qualitative analysis in the years 1950s to 1970s, is revisited to be used in a simple though highly efficient and green procedure for analyte preconcentration prior to its determination by the microanalytical techniques presently available. The proposed preconcentration technique is based on the dropwise delivery of a small volume of sample to a filter paper substrate, assisted by a flow-injection-like system. The filter paper is maintained in a small circular heated oven (the ring oven). Drops of the sample solution diffuse by capillarity from the center to a circular area of the paper substrate. After the total sample volume has been delivered, a ring with a sharp (c.a. 350 μm) circular contour, of about 2.0 cm diameter, is formed on the paper to contain most of the analytes originally present in the sample volume. Preconcentration coefficients of the analyte can reach 250-fold (on a m/m basis) for a sample volume as small as 600 μL. The proposed system and procedure have been evaluated to concentrate Na, Fe, and Cu in fuel ethanol, followed by simultaneous direct determination of these species in the ring contour, employing the microanalytical technique of laser induced breakdown spectroscopy (LIBS). Detection limits of 0.7, 0.4, and 0.3 μg mL(-1) and mean recoveries of (109 ± 13)%, (92 ± 18)%, and (98 ± 12)%, for Na, Fe, and Cu, respectively, were obtained in fuel ethanol. It is possible to anticipate the application of the technique, coupled to modern microanalytical and multianalyte techniques, to several analytical problems requiring analyte preconcentration and/or sample stabilization.

  11. Microfabricated diffusion source

    DOEpatents

    Oborny, Michael C [Albuquerque, NM; Frye-Mason, Gregory C [Cedar Crest, NM; Manginell, Ronald P [Albuquerque, NM

    2008-07-15

    A microfabricated diffusion source to provide for a controlled diffusion rate of a vapor comprises a porous reservoir formed in a substrate that can be filled with a liquid, a headspace cavity for evaporation of the vapor therein, a diffusion channel to provide a controlled diffusion of the vapor, and an outlet to release the vapor into a gas stream. The microfabricated diffusion source can provide a calibration standard for a microanalytical system. The microanalytical system with an integral diffusion source can be fabricated with microelectromechanical systems technologies.

  12. The Amsterdam quintuplet nuclear microprobe

    NASA Astrophysics Data System (ADS)

    van den Putte, M. J. J.; van den Brand, J. F. J.; Jamieson, D. N.; Rout, B.; Szymanski, R.

    2003-09-01

    A new nuclear microprobe comprising of a quintuplet lens system is being constructed at the Ion Beam Facility of the "Vrije Universiteit" Amsterdam in collaboration with the Microanalytical Research Centre of the University of Melbourne. An overview of the Amsterdam set-up will be presented. Detailed characterisation of the individual lenses was performed with the grid shadow method using a 2000 mesh Cu grid mounted at a relative angle of 0.5° to the vertical lens line focus. The lenses were found to have very low parasitic aberrations equal or below the minimum detectable limit for the method, which was approximately 0.1% for the sextupole component and 0.2% for the octupole component. We present experimental and theoretical grid shadow patterns, showing results for all five lenses.

  13. Chemical preconcentrator with integral thermal flow sensor

    DOEpatents

    Manginell, Ronald P.; Frye-Mason, Gregory C.

    2003-01-01

    A chemical preconcentrator with integral thermal flow sensor can be used to accurately measure fluid flow rate in a microanalytical system. The thermal flow sensor can be operated in either constant temperature or constant power mode and variants thereof. The chemical preconcentrator with integral thermal flow sensor can be fabricated with the same MEMS technology as the rest of the microanlaytical system. Because of its low heat capacity, low-loss, and small size, the chemical preconcentrator with integral thermal flow sensor is fast and efficient enough to be used in battery-powered, portable microanalytical systems.

  14. Fluorescence-based Sensing of 2,4,6-Trinitrotoluene (TNT) Using a Multi-channeled Poly(methyl methacrylate) (PMMA) Microimmunosensor

    DTIC Science & Technology

    2010-01-22

    Davidson, Y.Y.; McWhorter, C.S.; Soper , S.A.; McCarley, R.L. Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical...J.; Hupert, M.L.; Patterson, D.; Gottert, J.; McCarley, R.L.; Nikitopoulos, D.; Murphy, M.C.; Soper , S.A. Highly efficient circulating tumor cell

  15. Determination of Fluorine in Fourteen Microanalytical Geologic Reference Materials using SIMS, EPMA, and Proton Induced Gamma Ray Emission (PIGE) Analysis

    NASA Astrophysics Data System (ADS)

    Guggino, S. N.; Hervig, R. L.

    2010-12-01

    Fluorine (F) is a volatile constituent of magmas and hydrous minerals, and trace amounts of F are incorporated into nominally anhydrous minerals such as olivine and clinopyroxene. Microanalytical techniques are routinely used to measure trace amounts of F at both high sensitivity and high spatial resolution in glasses and crystals. However, there are few well-established F concentrations for the glass standards routinely used in microanalytical laboratories, particularly standards of low silica, basaltic composition. In this study, we determined the F content of fourteen commonly used microanalytical glass standards of basaltic, intermediate, and rhyolitic composition. To serve as calibration standards, five basaltic glasses with ~0.2 to 2.5 wt% F were synthesized and characterized. A natural tholeiite from the East Pacific Rise was mixed with variable amounts of CaF2. The mixture was heated in a 1 atmosphere furnace to 1440 °C at fO2 = NNO for 30 minutes and quenched in water. Portions of the run products were studied by electron probe microanalysis (EPMA) and secondary ion mass spectrometry (SIMS). The EPMA used a 15 µm diameter defocused electron beam with a 15 kV accelerating voltage and a 25 nA primary current, a TAP crystal for detecting FKα X-rays, and Biotite 3 as the F standard. The F contents by EPMA agreed with the F added to the basalts after correction for mass loss during melting. The SIMS analyses used a primary beam of 16O- and detection of low-energy negative ions (-5 kV) at a mass resolution that resolved 18OH. Both microanalytical techniques confirmed homogeneity, and the SIMS calibration defined by EPMA shows an excellent linear trend with backgrounds of 2 ppm or less. Analyses of basaltic glass standards based on our synthesized calibration standards gave the following F contents and 2σ errors (ppm): ALV-519 = 83 ± 3; BCR-2G = 359 ± 6; BHVO-2G = 322 ± 15; GSA-1G = 10 ± 1; GSC-1G = 11 ± 1; GSD-1G = 19 ± 2; GSE-1G = 173 ± 1; KL2G (MPI-DING) = 101 ± 1; ML3B-G (MPI-DING) = 49 ± 17. These values are lower than published values for BCR-2 and BHVO-2 (unmelted powders) and the “information values” for the MPI-DING glass standards. Proton Induced Gamma ray Emission (PIGE) was tested for the high silica samples. PIGE analyses (1.7 MeV Tandem Accelerator; reaction type: 19F(p, αγ)16O; primary current = 20-30 nA; incident beam voltage = 1.5 MeV) were calibrated with a crystal of fluor-topaz (F = 20.3 wt%) and gave F values of: NIST 610 = 266 ± 14 ppm; NIST 620 = 54 ± 5 ppm; and UTR-2 = 1432 ± 32 ppm. SIMS calibration defined by the PIGE analyses shows an excellent linear trend with low background similar to the basaltic calibration. The F concentrations of intermediate MPI-DING glasses were determined based on SIMS calibration generated from the PIGE analysis above. The F concentrations and 2σ errors (ppm) are: T1G = 219.9 ± 6.8; StHs/680-G = 278.0 ± 2.0 ppm. This study revealed a large matrix effect between the high-silica and basaltic glasses, thus requiring the use of appropriate standards and separate SIMS calibrations when analyzing samples of different compositions.

  16. Today's and Tomorrow's Instruments.

    PubMed

    Conty, Claude

    2001-03-01

    This article will discuss the importance of Raimond Castaing's thesis on the genesis of a nondestructive and truly quantitative microanalytical method that assisted the scientific community in moving forward in the development of microanalytical instruments. I will also share with you my recollection of the decades of improvement in the electron probe microanalyzer (EPMA), that has allowed us to reach our present level of instrument sophistication, and I will explore with you my thoughts on the future evolution of this technique. To conclude, I will present the current status of related microanalysis techniques developed under Castaing in Orsay in the 1960s, as Castaing's interest in microanalysis was not limited to electron probe microanalysis alone.

  17. Method for making electro-fluidic connections in microfluidic devices

    DOEpatents

    Frye-Mason, Gregory C.; Martinez, David; Manginell, Ronald P.; Heller, Edwin J.; Chanchani, Rajen

    2004-08-10

    A method for forming electro-fluidic interconnections in microfluidic devices comprises forming an electrical connection between matching bond pads on a die containing an active electrical element and a microfluidic substrate and forming a fluidic seal ring that circumscribes the active electrical element and a fluidic feedthrough. Preferably, the electrical connection and the seal ring are formed in a single bonding step. The simple method is particularly useful for chemical microanalytical systems wherein a plurality of microanalytical components, such as a chemical preconcentrator, a gas chromatography column, and a surface acoustic wave detector, are fluidically interconnected on a hybrid microfluidic substrate having electrical connection to external support electronics.

  18. Planar micromixer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fiechtner, Gregory J; Singh, Anup K; Wiedenman, Boyd J

    2008-03-18

    The present embodiment describes a laminar-mixing embodiment that utilizes simple, three-dimensional injection. Also described is the use of the embodiment in combination with wide and shallow sections of channel to affect rapid mixing in microanalytical systems. The shallow channel sections are constructed using all planar micromachining techniques, including those based on isotropic etching. The planar construction enables design using minimum dispersion concepts that, in turn, enable simultaneous mixing and injection into subsequent chromatography channels.

  19. A new basaltic glass microanalytical reference material for multiple techniques

    USGS Publications Warehouse

    Wilson, Steve; Koenig, Alan; Lowers, Heather

    2012-01-01

    The U.S. Geological Survey (USGS) has been producing reference materials since the 1950s. Over 50 materials have been developed to cover bulk rock, sediment, and soils for the geological community. These materials are used globally in geochemistry, environmental, and analytical laboratories that perform bulk chemistry and/or microanalysis for instrument calibration and quality assurance testing. To answer the growing demand for higher spatial resolution and sensitivity, there is a need to create a new generation of microanalytical reference materials suitable for a variety of techniques, such as scanning electron microscopy/X-ray spectrometry (SEM/EDS), electron probe microanalysis (EPMA), laser ablation inductively coupled mass spectrometry (LA-ICP-MS), and secondary ion mass spectrometry (SIMS). As such, the microanalytical reference material (MRM) needs to be stable under the beam, be homogeneous at scales of better than 10–25 micrometers for the major to ultra-trace element level, and contain all of the analytes (elements or isotopes) of interest. Previous development of basaltic glasses intended for LA-ICP-MS has resulted in a synthetic basaltic matrix series of glasses (USGS GS-series) and a natural basalt series of glasses (BCR-1G, BHVO-2G, and NKT-1G). These materials have been useful for the LA-ICP-MS community but were not originally intended for use by the electron or ion beam community. A material developed from start to finish with intended use in multiple microanalytical instruments would be useful for inter-laboratory and inter-instrument platform comparisons. This article summarizes the experiments undertaken to produce a basalt glass reference material suitable for distribution as a multiple-technique round robin material. The goal of the analytical work presented here is to demonstrate that the elemental homogeneity of the new glass is acceptable for its use as a reference material. Because the round robin exercise is still underway, only nominal compositional ranges for each element are given in the article.

  20. Microfabricated thermionic detector

    DOEpatents

    Lewis, Patrick R; Manginell, Ronald P; Wheeler, David R; Trudell, Daniel E

    2012-10-30

    A microfabricated TID comprises a microhotplate and a thermionic source disposed on the microhotplate. The microfabricated TID can provide high sensitivity and selectivity to nitrogen- and phosphorous-containing compounds and other compounds containing electronegative function groups. The microfabricated TID can be microfabricated with semiconductor-based materials. The microfabricated TID can be combined with a microfabricated separation column and used in microanalytical system for the rapid on-site detection of pesticides, chemical warfare agents, explosives, pharmaceuticals, and other organic compounds that contain nitrogen or phosphorus.

  1. Capacitive chemical sensor

    DOEpatents

    Manginell, Ronald P; Moorman, Matthew W; Wheeler, David R

    2014-05-27

    A microfabricated capacitive chemical sensor can be used as an autonomous chemical sensor or as an analyte-sensitive chemical preconcentrator in a larger microanalytical system. The capacitive chemical sensor detects changes in sensing film dielectric properties, such as the dielectric constant, conductivity, or dimensionality. These changes result from the interaction of a target analyte with the sensing film. This capability provides a low-power, self-heating chemical sensor suitable for remote and unattended sensing applications. The capacitive chemical sensor also enables a smart, analyte-sensitive chemical preconcentrator. After sorption of the sample by the sensing film, the film can be rapidly heated to release the sample for further analysis. Therefore, the capacitive chemical sensor can optimize the sample collection time prior to release to enable the rapid and accurate analysis of analytes by a microanalytical system.

  2. A microanalytic study of self-regulated learning processes of expert, non-expert, and at-risk science students

    NASA Astrophysics Data System (ADS)

    Dibenedetto, Maria K.

    2009-12-01

    The present investigation sought to examine differences in the self-regulated learning processes and beliefs of students who vary in their level of expertise in science and to investigate if there are gender differences. Participants were 51 ethnically diverse 11th grade students from three parochial high schools consisting of 34 females and 17 males. Students were grouped as either expert, non-expert, or at-risk based on the school's classification. Students were provided with a short passage on tornados to read and study. The two achievement measures obtained were the Tornado Knowledge Test : ten short-answer questions and the Conceptual Model Test : a question which required the students to draw and describe the three sequential images of tornado development from the textual description of the three phases. A microanalytic methodology was used which consists of asking a series of questions aimed at assessing students' psychological behaviors, feelings, and thoughts in each of Zimmerman's three phases of self-regulation: forethought, performance, and reflection. These questions were asked of the students while they were engaged in learning. Two additional measures were obtained: the Rating Student Self-Regulated Learning Outcomes: A Teacher Scale (RSSRL) and the Self-Efficacy for Self-Regulated Learning (SELF). Analysis of variance, chi square analysis, and post hoc test results showed significant expertise differences, large effect sizes, and positive linear trends on most measures. Regarding gender, there were significant differences on only two measures. Correlational analyses also revealed significant relations among the self-regulatory subprocesses across the three phases. The microanalytic measures were combined across the three phases and entered into a regression formula to predict the students' scores on the Tornado Knowledge Test. These self-regulatory processes explained 77% of the variance in the Tornado Knowledge Test, which was a significant and substantial effect. Prior to this investigation, there have been no studies which have tested Zimmerman's three phase model on an academic task, such as science, within an expertise framework. Implications from the present study suggest that students varying in expertise level in science achievement also vary in self-regulatory behavior, and that gender is not a significant factor.

  3. Fluidic optics

    NASA Astrophysics Data System (ADS)

    Whitesides, George M.; Tang, Sindy K. Y.

    2006-09-01

    Fluidic optics is a new class of optical system with real-time tunability and reconfigurability enabled by the introduction of fluidic components into the optical path. We describe the design, fabrication, operation of a number of fluidic optical systems, and focus on three devices, liquid-core/liquid-cladding (L2) waveguides, microfluidic dye lasers, and diffraction gratings based on flowing, crystalline lattices of bubbles, to demonstrate the integration of microfluidics and optics. We fabricate these devices in poly(dimethylsiloxane) (PDMS) with soft-lithographic techniques. They are simple to construct, and readily integrable with microanalytical or lab-on-a-chip systems.

  4. How Does Microanalysis of Mother-Infant Communication Inform Maternal Sensitivity and Infant Attachment?

    PubMed Central

    Beebe, Beatrice; Steele, Miriam

    2013-01-01

    Microanalysis research on 4-month mother-infant face-to-face communication operates like a “social microscope” and identifies aspects of maternal sensitivity and the origins of attachment with a more detailed lens. We hope to enhance a dialogue between these two paradigms, microanalysis of mother-infant communication and maternal sensitivity and emerging working models of attachment. The prediction of infant attachment from microanalytic approaches and their contribution to concepts of maternal sensitivity are described. We summarize aspects of one microanalytic study by Beebe and colleagues (2010) that documents new communication patterns between mothers and infants at 4 months that predict future disorganized (vs. secure) attachment. The microanalysis approach opens up a new window on the details of the micro-processes of face-to-face communication. It provides a new, rich set of behaviors with which to extend our understanding of the origins of infant attachment and of maternal sensitivity. PMID:24299136

  5. How does microanalysis of mother-infant communication inform maternal sensitivity and infant attachment?

    PubMed

    Beebe, Beatrice; Steele, Miriam

    2013-01-01

    Microanalysis research on 4-month infant-mother face-to-face communication operates like a "social microscope" and identifies aspects of maternal sensitivity and the origins of attachment with a more detailed lens. We hope to enhance a dialogue between these two paradigms, microanalysis of mother-infant communication and maternal sensitivity and emerging working models of attachment. The prediction of infant attachment from microanalytic approaches and their contribution to concepts of maternal sensitivity are described. We summarize aspects of one microanalytic study by Beebe and colleagues published in 2010 that documents new communication patterns between mothers and infants at 4 months that predict future disorganized (vs. secure) attachment. The microanalysis approach opens up a new window on the details of the micro-processes of face-to-face communication. It provides a new, rich set of behaviors with which to extend our understanding of the origins of infant attachment and of maternal sensitivity.

  6. Microanalytic Assessment of Self-Regulated Learning During Clinical Reasoning Tasks: Recent Developments and Next Steps.

    PubMed

    Cleary, Timothy J; Durning, Steven J; Artino, Anthony R

    2016-11-01

    Helping medical educators obtain and use assessment data to assist medical students, residents, and physicians in reducing diagnostic errors and other forms of ineffective clinical practice is of critical importance. Self-Regulated Learning-Microanalytic Assessment and Training is an assessment-to-intervention framework designed to address this need by generating data about trainees' strategic processes (e.g., focusing on clinical task procedures), regulatory processes (e.g., planning how to do a task), and motivational processes (e.g., increasing confidence for performing a task) as they perform clinical activities. In this article, the authors review several studies that have used an innovative assessment approach, called self-regulated learning (SRL) microanalysis, to generate data about how trainees regulate their thinking and actions during clinical reasoning tasks. Across the studies, initial findings revealed that medical students often do not exhibit strategic thinking and action during clinical reasoning practice tasks even though some regulatory processes (e.g., planning) are predictive of important medical education outcomes. Further, trainees' motivation beliefs, strategic thinking, and self-evaluative judgments tend to shift rapidly during clinical skills practice and may also vary across different parts of a patient encounter. Collectively, these findings underscore the value of dynamically assessing trainees' SRL as they complete clinical tasks. The findings also set the stage for exploring how medical educators can best use SRL microanalytic assessment data to guide remedial practices and the provision of feedback to trainees. Implications and future research directions for connecting assessments to intervention in medical education are discussed.

  7. Microanalytical Efforts in Support of NASA's Materials Science Programs

    NASA Technical Reports Server (NTRS)

    Gillies, Donald C.

    2004-01-01

    Following a brief overview of NASA s Microgravity Materials Science programs, specific examples will be given showing electron beam and optical microscopic applications to two-phase glass structures, dendrite tip radii, solid solution semiconductors, undercooled two-phase stainless steels and meteorites.

  8. Microstructural and Microanalytical Study on Concrete Exposed to the Sulfate Environment

    NASA Astrophysics Data System (ADS)

    Qing, Fang; Beixing, Li; Jiangang, Yin; Xiaolu, Yuan

    2017-11-01

    Microstructural properties have been examined to investigate the effect of mineral admixtures on the sulfate resistance of concrete. Concrete and cement paste specimens made with ordinary Portland cement (OPC) or ordinary Portland cement incorporating 20% fly ash (FA) or 30% ground blast furnace slag (GBFS), were made and exposed to 250 cycles of the cyclic sulfate environment. Microstructural and Microanalytical study was conducted by means of x-ray diffraction (XRD), scanning electron microscope (SEM), energy dispersive spectroscopy (EDS) and mercury intrusion porosimetry (MIP). Results indicate that the pore structure of concrete after sulfate exposure possesses the fractal feature. The OPC concrete presents more complex pore internal surface, higher porosity and less micro-pores than the concrete incorporating fly ash and GBFS. Portlandite in OPC concrete and OPC-FA concrete is mainly converted to gypsum; while for OPC-GBFS concrete, both gypsum and ettringite are formed. In the cyclic sulfate environment, repeated hydration and dehydration of sulfates produce the expansive stress in pores, aggravating the demolishment of concrete structure.

  9. Next-generation confirmatory disease diagnostics

    NASA Astrophysics Data System (ADS)

    Lin, Robert; Gerver, Rachel; Karns, Kelly; Apori, Akwasi A.; Denisin, Aleksandra K.; Herr, Amy E.

    2014-06-01

    Microfluidic tools are advancing capabilities in screening diagnostics for use in near-patient settings. Here, we review three case studies to illustrate the flexibility and analytical power offered by microanalytical tools. We first overview a near-patient tool for detection of protein markers found in cerebrospinal fluid (CSF), as a means to identify the presence of cerebrospinal fluid in nasal mucous - an indication that CSF is leaking into the nasal cavity. Microfluidic design allowed integration of several up-stream preparatory steps and rapid, specific completion of the human CSF protein assay. Second, we overview a tear fluid based assay for lactoferrin, a protein produced in the lacrimal gland, then secreted into tear fluid. Tear Lf is a putative biomarker for primary SS. A critical contribution of this and related work being measurement of Lf, even in light of well-known and significant matrix interactions and losses during the tear fluid collection and preparation. Lastly, we review a microfluidic barcode platform that enables rapid measurement of multiple infectious disease biomarkers in human sera. The assay presents a new approach to multiplexed biomarker detection, yet in a simple straight microchannel - thus providing a streamlined, simplified microanalytical platform, as is relevant to robust operation in diagnostic settings. We view microfluidic design and analytical chemistry as the basis for emerging, sophisticated assays that will advance not just screening diagnostic technology, but confirmatory assays, sample preparation and handling, and thus introduction and utilization of new biomarkers and assay formats.

  10. Synthesis, characterization and biological properties of thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes.

    PubMed

    Chohan, Zahid H; Sumrra, Sajjad H

    2012-04-01

    A new series of biologically active thienyl derived triazole Schiff bases and their oxovanadium(IV) complexes have been synthesized and characterized on the basis of physical (m.p., magnetic susceptibility and conductivity), spectral (IR, ¹H and ¹³C NMR, electronic and mass spectrometry) and microanalytical data. All the Schiff base ligands and their oxovanadium(IV) complexes have been subjected to in vitro antibacterial activity against four Gram-negative (Escherichia coli, Shigella flexneri, Pseudomonas aeruginosa, Salmonella enterica serover typhi) and two Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacterial strains and, for in vitro antifungal activity against Trichophyton longifucus, Candida albican, Aspergillus flavus, Microscopum canis, Fusarium solani and Candida glabrata. Brine shrimp bioassay was also carried out to check the cytotoxic nature of these compounds.

  11. Soil fertility affects elemental distribution in needles of the conifer Araucaria angustifolia: A microanalytical study

    USDA-ARS?s Scientific Manuscript database

    Araucaria angustifolia is a conifer species found in South American subtropical forests that comprises less than 3% of the native vegetation. Thus, little is known concerning the accumulation of nutritional elements in its needles. In this study, scanning electron microscopy (SEM) coupled with energ...

  12. Entrepreneur Grows Microswitch Company

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Czaja, Danny; Christenson, Todd

    2014-10-24

    Todd Christenson took advantage of Sandia National Laboratories’ Entrepreneurial Separation to Transfer Technology (ESTT) program to start HT MicroAnalytical (HT Micro) in 2003 in order to apply his specialized expertise in high aspect ratio microfabrication (HARM) technology gained while at Sandia to the creation of the world’s smallest electromechanical switches.

  13. Practices of Grading: An Ethnographic Study of Educational Assessment

    ERIC Educational Resources Information Center

    Kalthoff, Herbert

    2013-01-01

    The school as an institution assumes that students' grades are constituted by their assessments. This paper examines the background of this presupposition and provides a micro-analytical perspective of the grading practice of teachers in German High Schools ("Gymnasium"). This paper conceptualises the theoretical framework of the…

  14. Critical Narrative Analysis: The Interplay of Critical Discourse and Narrative Analyses

    ERIC Educational Resources Information Center

    Souto-Manning, Mariana

    2014-01-01

    In this article, I question the micro-macro separation in discourse analysis, the separation of personal and institutional discourses. I apply a mostly macroanalytic perspective (critical discourse analysis [CDA]) to inform a predominantly microanalytic perspective (analysis of conversational narratives) and vice versa. In the combination of these…

  15. Computational Methodology for Absolute Calibration Curves for Microfluidic Optical Analyses

    PubMed Central

    Chang, Chia-Pin; Nagel, David J.; Zaghloul, Mona E.

    2010-01-01

    Optical fluorescence and absorption are two of the primary techniques used for analytical microfluidics. We provide a thorough yet tractable method for computing the performance of diverse optical micro-analytical systems. Sample sizes range from nano- to many micro-liters and concentrations from nano- to milli-molar. Equations are provided to trace quantitatively the flow of the fundamental entities, namely photons and electrons, and the conversion of energy from the source, through optical components, samples and spectral-selective components, to the detectors and beyond. The equations permit facile computations of calibration curves that relate the concentrations or numbers of molecules measured to the absolute signals from the system. This methodology provides the basis for both detailed understanding and improved design of microfluidic optical analytical systems. It saves prototype turn-around time, and is much simpler and faster to use than ray tracing programs. Over two thousand spreadsheet computations were performed during this study. We found that some design variations produce higher signal levels and, for constant noise levels, lower minimum detection limits. Improvements of more than a factor of 1,000 were realized. PMID:22163573

  16. The Interactional Management of Claims of Insufficient Knowledge in English Language Classrooms

    ERIC Educational Resources Information Center

    Sert, Olcay; Walsh, Steve

    2013-01-01

    This paper primarily investigates the interactional unfolding and management of "claims of insufficient knowledge" (Beach and Metzger 1997) in two English language classrooms from a multi-modal, conversation-analytic perspective. The analyses draw on a close, micro-analytic account of sequential organisation of talk as well as on various…

  17. Shifting Attention

    ERIC Educational Resources Information Center

    Ingram, Jenni

    2014-01-01

    This article examines the shifts in attention and focus as one teacher introduces and explains an image that represents the processes involved in a numeric problem that his students have been working on. This paper takes a micro-analytic approach to examine how the focus of attention shifts through what the teacher and students do and say in the…

  18. Entrepreneur Grows Microswitch Company

    ScienceCinema

    Czaja, Danny; Christenson, Todd

    2018-05-30

    Todd Christenson took advantage of Sandia National Laboratories’ Entrepreneurial Separation to Transfer Technology (ESTT) program to start HT MicroAnalytical (HT Micro) in 2003 in order to apply his specialized expertise in high aspect ratio microfabrication (HARM) technology gained while at Sandia to the creation of the world’s smallest electromechanical switches.

  19. Examining Shifts in Medical Students' Microanalytic Motivation Beliefs and Regulatory Processes during a Diagnostic Reasoning Task

    ERIC Educational Resources Information Center

    Cleary, Timothy J.; Dong, Ting; Artino, Anthony R., Jr.

    2015-01-01

    This study examined within-group shifts in the motivation beliefs and regulatory processes of second-year medical students as they engaged in a diagnostic reasoning activity. Using a contextualized assessment methodology called self-regulated learning microanalysis, the authors found that the 71 medical student participants showed statistically…

  20. Bullying in Context: Stories of Bullying on an Internet Discussion Board

    ERIC Educational Resources Information Center

    Osvaldsson, Karin

    2011-01-01

    The paper examines how young people describe experiences of bullying when participating in an Internet community dedicated to young people experiencing mental health problems. The micro-analytic focus demonstrates how young people construct their identities in relation to their telling about their experiences of being victims of bullying,…

  1. Tensions in the Biology Laboratory: What Are They?

    ERIC Educational Resources Information Center

    Tan, Aik-Ling

    2008-01-01

    The purpose of this paper is to identify tensions in teacher-student interaction in a high school biology laboratory. Using micro-analytic analysis of classroom talk, the interaction between the students and a teacher working in the biology laboratory session on "Reproduction in Plants" is studied. The two tensions highlighted here are…

  2. Affordances for Participation: Children's Appropriation of Rules in a Reggio Emilia School

    ERIC Educational Resources Information Center

    Martin, Cathrin; Evaldsson, Ann-Carita

    2012-01-01

    This study explores how young children appropriate school rules and what opportunities for active participation are afforded in a Reggio Emilia elementary classroom with particular interest in the interactional and communicative competences children display in situated practice. An ethnographic and microanalytic approach is used to study how the…

  3. Late-Preterm Birth, Maternal Symptomatology, and Infant Negativity

    PubMed Central

    Voegtline, Kristin M.; Stifter, Cynthia A.

    2010-01-01

    The present study examined infant negativity and maternal symptomatology by term status in a predominately low-income, rural sample of 132 infants (66 late-preterm) and their mothers. Late-preterm and term infants were group-matched by race, income, and maternal age. Maternal depression and anxiety symptoms were measured with the Brief Symptom Inventory 18 (BSI-18) when infants were 2 and 6 months of age. Also at 6 months, infant negativity was assessed by global observer ratings, maternal ratings, and microanalytic behavioral coding of fear and frustration. Results indicate that after controlling for infant age, late-preterm status predicted higher ratings of infant negativity by mothers, but not by global observers or microanalytic coding, despite a positive association in negativity across the three measures. Further, mothers of late-preterm infants reported more elevated and chronic co-morbid symptoms of depression and anxiety, which in turn, was related to concurrent maternal ratings of their infant’s negativity. Mothers response to late-preterm birth and partiality in the assessment of their infant’s temperament is discussed. PMID:20732715

  4. Development in Dialogic Teaching Skills: A Micro-Analytic Case Study of a Pre-Service ITA

    ERIC Educational Resources Information Center

    Rine, Emily F.

    2009-01-01

    As universities have come to depend increasingly on international, non-native English-speaking graduate students to teach many of the undergraduate courses, they have created International Teaching Assistant (ITA) programs in order to provide ITAs with the cultural, pedagogical, and linguistic skills needed to instruct in an American university…

  5. Surface Analysis and Tools

    NASA Technical Reports Server (NTRS)

    Miyoshi, Kazuhisa

    2002-01-01

    This article is a chapter of the book entitled, "Tribology of Mechanical Systems," to be published by ASME Press, New York, NY. It describes selected analytical techniques, which are being used in understanding phenomena and mechanisms of oxidation, adhesion, bonding, friction, erosion, abrasion, and wear, and in defining the problems. The primary emphasis is on microanalytical approaches to engineering surfaces.

  6. Microanalytic Case studies of Individual Participation Patterns in an Asynchronous Online Discussion in an Undergraduate Blended Course

    ERIC Educational Resources Information Center

    Wise, Alyssa Friend; Perera, Nishan; Hsiao, Ying-Ting; Speer, Jennifer; Marbouti, Farshid

    2012-01-01

    This study presents three case studies of students' participation patterns in an online discussion to address the gap in our current understanding of how "individuals" experience asynchronous learning environments. Cases were constructed via microanalysis of log-file data, post contents, and the evolving discussion structure. The first student was…

  7. [Microanalytical determinations of gold alloys for fixed dentures].

    PubMed

    Lotito, M; Negri, P; Fraschini, M

    1993-01-01

    In this work the authors analyse gold alloys for fixed prosthesis by X-ray spectrometry in energy dispersion (EDS). The results of this analysis, given in graphic and table form, show remarkable differences in alloy composition. For this reason recommended dentists are to be attentive and severe in the control of gold alloys for fixed prosthesis.

  8. A microanalytical method for the determination of dihydroquercetin in wood

    Treesearch

    Richard W. Hemingway; W.E. Hillis

    1969-01-01

    Dihydroquercetin (3,5,7,3',4'-pentahydroxyflavanone) is a major constituent of the alcohol soluble materials in the wood of Larch species and the wood and bark of Douglas-fir. A sensitive analytical method is needed to enable rapid assessment of amounts of dihydroquercetin (DHQ) when processing commercial materials and for studies of biochemical aspects of...

  9. Working Memory Capacity and the Antisaccade Task: A Microanalytic-Macroanalytic Investigation of Individual Differences in Goal Activation and Maintenance

    ERIC Educational Resources Information Center

    Meier, Matt E.; Smeekens, Bridget A.; Silvia, Paul J.; Kwapil, Thomas R.; Kane, Michael J.

    2018-01-01

    The association between working memory capacity (WMC) and the antisaccade task, which requires subjects to move their eyes and attention away from a strong visual cue, supports the claim that WMC is partially an attentional construct (Kane, Bleckley, Conway, & Engle, 2001; Unsworth, Schrock, & Engle, 2004). Specifically, the…

  10. Microchannel gel electrophoretic separation systems and methods for preparing and using

    DOEpatents

    Herr, Amy E; Singh, Anup K; Throckmorton, Daniel J

    2015-02-24

    A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The microfluidic immunoassays are performed by gel electrophoretic separation and quantifying analyte concentration based upon conventional polyacrylamide gel electrophoresis (PAGE). To retain biological activity of proteins and maintain intact immune complexes, native PAGE conditions were employed. Both direct (non-competitive) and competitive immunoassay formats are demonstrated in microchips for detecting toxins and biomarkers (cytokines, c-reactive protein) in bodily fluids (serum, saliva, oral fluids). Further, a description of gradient gels fabrication is included, in an effort to describe methods we have developed for further optimization of on-chip PAGE immunoassays. The described chip-based PAGE immunoassay method enables immunoassays that are fast (minutes) and require very small amounts of sample (less than a few microliters). Use of microfabricated chips as a platform enables integration, parallel assays, automation and development of portable devices.

  11. Microchannel gel electrophoretic separation systems and methods for preparing and using

    DOEpatents

    Herr, Amy; Singh, Anup K; Throckmorton, Daniel J

    2013-09-03

    A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The microfluidic immunoassays are performed by gel electrophoretic separation and quantifying analyte concentration based upon conventional polyacrylamide gel electrophoresis (PAGE). To retain biological activity of proteins and maintain intact immune complexes, native PAGE conditions were employed. Both direct (non-competitive) and competitive immunoassay formats are demonstrated in microchips for detecting toxins and biomarkers (cytokines, c-reactive protein) in bodily fluids (serum, saliva, oral fluids). Further, a description of gradient gels fabrication is included, in an effort to describe methods we have developed for further optimization of on-chip PAGE immunoassays. The described chip-based PAGE immunoassay method enables immunoassays that are fast (minutes) and require very small amounts of sample (less than a few microliters). Use of microfabricated chips as a platform enables integration, parallel assays, automation and development of portable devices.

  12. Microanalytical study of a ferrous agricultural tool recovered from a historical site in Rio de Janeiro

    NASA Astrophysics Data System (ADS)

    Campos, G. N.; Solórzano, I. G.

    The present work has as its objective a microanalytical study of a metallic archeological artifact using methods of optical microscopy (MO), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The object of the study corresponds to an agricultural tool (a hoe) from the Brazilian colonial period, dating from the late XVIII century, removed from an archeological site (Sítio Rochedo) in excavations conducted by researchers of the Brazilian Archeological Institute. Sample preparation required a meticulous procedure in view of the fragility of the object. The hoe has been suffering the action of oxidation-corrosion over the years, thereby making the impregnation of mineral sediments possible. A detailed metallographic analysis, coupled with spectroscopic SEM and TEM measurements, allows one to conclude that the hoe was made of puddle iron, retaining significant amount of slag. The hoe was probably made by African slaves who had metallurgical knowledge acquired from their ancestors under Portuguese colonization. The equi-axial microstructure of ferrite grains, together with the alignment of slag inclusions, strongly suggest a metal forming procedure conducted on low-carbon puddled iron, followed by heat treatment and then cooling at a slow rate.

  13. Insights into the varnishes of historical musical instruments using synchrotron micro-analytical methods

    NASA Astrophysics Data System (ADS)

    Echard, J.-P.; Cotte, M.; Dooryhee, E.; Bertrand, L.

    2008-07-01

    Though ancient violins and other stringed instruments are often revered for the beauty of their varnishes, the varnishing techniques are not much known. In particular, very few detailed varnish analyses have been published so far. Since 2002, a research program at the Musée de la musique (Paris) is dedicated to a detailed description of varnishes on famous ancient musical instruments using a series of novel analytical methods. For the first time, results are presented on the study of the varnish from a late 16th century Venetian lute, using synchrotron micro-analytical methods. Identification of both organic and inorganic compounds distributed within the individual layers of a varnish microsample has been performed using spatially resolved synchrotron Fourier transform infrared microscopy. The univocal identification of the mineral phases is obtained through synchrotron powder X-ray diffraction. The materials identified may be of utmost importance to understand the varnishing process and its similarities with some painting techniques. In particular, the proteinaceous binding medium and the calcium sulfate components (bassanite and anhydrite) that have been identified in the lower layers of the varnish microsample could be related, to a certain extent, to the ground materials of earlier Italian paintings.

  14. Fundamentals and practice for ultrasensitive laser-induced fluorescence detection in microanalytical systems.

    PubMed

    Johnson, Mitchell E; Landers, James P

    2004-11-01

    Laser-induced fluorescence is an extremely sensitive method for detection in chemical separations. In addition, it is well-suited to detection in small volumes, and as such is widely used for capillary electrophoresis and microchip-based separations. This review explores the detailed instrumental conditions required for sub-zeptomole, sub-picomolar detection limits. The key to achieving the best sensitivity is to use an excitation and emission volume that is matched to the separation system and that, simultaneously, will keep scattering and luminescence background to a minimum. We discuss how this is accomplished with confocal detection, 90 degrees on-capillary detection, and sheath-flow detection. It is shown that each of these methods have their advantages and disadvantages, but that all can be used to produce extremely sensitive detectors for capillary- or microchip-based separations. Analysis of these capabilities allows prediction of the optimal means of achieving ultrasensitive detection on microchips.

  15. The Influence of Maternal Language Responsiveness on the Expressive Speech Production of Children with Autism Spectrum Disorders: A Microanalysis of Mother-Child Play Interactions

    ERIC Educational Resources Information Center

    Walton, Katherine M.; Ingersoll, Brooke R.

    2015-01-01

    Adult responsiveness is related to language development both in young typically developing children and in children with autism spectrum disorders, such that parents who use more responsive language with their children have children who develop better language skills over time. This study used a micro-analytic technique to examine how two facets…

  16. Temperature programmable microfabricated gas chromatography column

    DOEpatents

    Manginell, Ronald P.; Frye-Mason, Gregory C.

    2003-12-23

    A temperature programmable microfabricated gas chromatography column enables more efficient chemical separation of chemical analytes in a gas mixture by the integration of a resistive heating element and temperature sensing on the microfabricated column. Additionally, means are provided to thermally isolate the heated column from their surroundings. The small heat capacity and thermal isolation of the microfabricated column improves the thermal time response and power consumption, both important factors for portable microanalytical systems.

  17. Spectroscopic Studies of Nuclear Submarine Atmospheres. I. Desorption and Analysis of Contaminants from Hopcalite

    DTIC Science & Technology

    A semi-microanalytical method is described for desorbing contaminants from Hopcalite , an oxide catalyst used in the purification of submarine...contaminants are desorbed from the Hopcalite by passing pressurized steam through a column of the catalyst. The various compounds are eluted from the column...appropriate solvent. Infrared spectral analyses of contaminants desorbed from Hopcalite following its use as a catalyst for the oxidation of pure

  18. Exploring Clinical Reasoning in Novices: A Self-Regulated Learning Microanalytic Approach

    DTIC Science & Technology

    2013-07-05

    important medical school performance outcomes. Self-Regulated Learning Microanalysis Social-cognitive researchers have defined SRL as “the...It is important to note at the outset, however, that our plan was not to use SRL microanalysis to comprehensively assess students’ reasoning skills...2.97 1.31 .29* 1.39 .51 .32 † 22 Discussion This study was important because it represents an initial attempt to examine SRL

  19. GSD-1G and MPI-DING Reference Glasses for In Situ and Bulk Isotopic Determination

    USGS Publications Warehouse

    Jochum, K.P.; Wilson, S.A.; Abouchami, W.; Amini, M.; Chmeleff, J.; Eisenhauer, A.; Hegner, E.; Iaccheri, L.M.; Kieffer, B.; Krause, J.; McDonough, W.F.; Mertz-Kraus, R.; Raczek, I.; Rudnick, R.L.; Scholz, Donna K.; Steinhoefel, G.; Stoll, B.; Stracke, A.; Tonarini, S.; Weis, D.; Weis, U.; Woodhead, J.D.

    2011-01-01

    This paper contains the results of an extensive isotopic study of United States Geological Survey GSD-1G and MPI-DING reference glasses. Thirteen different laboratories were involved using high-precision bulk (TIMS, MC-ICP-MS) and microanalytical (LA-MC-ICP-MS, LA-ICP-MS) techniques. Detailed studies were performed to demonstrate the large-scale and small-scale homogeneity of the reference glasses. Together with previously published isotopic data from ten other laboratories, preliminary reference and information values as well as their uncertainties at the 95% confidence level were determined for H, O, Li, B, Si, Ca, Sr, Nd, Hf, Pb, Th and U isotopes using the recommendations of the International Association of Geoanalysts for certification of reference materials. Our results indicate that GSD-1G and the MPI-DING glasses are suitable reference materials for microanalytical and bulk analytical purposes. Ce document contient les r??sultats d'une importante ??tude isotopique des verres de r??f??rence USGS GSD-1G et MPI-DING. Treize laboratoires diff??rents ont particip?? au travers de techniques analytiques de haute pr??cision travaillant soit sur ??chantillon total (TIMS, MC-ICP-MS) soit par microanalyse ??in situ?? (LA-MC-ICP-MS, LA-ICP-MS). ?? 2010 The Authors. Geostandards and Geoanalytical Research ?? 2010 International Association of Geoanalysts.

  20. Microanalysis characterization of bioactive protein-bound polysaccharides produced by Amanita ponderosa cultures.

    PubMed

    Salvador, Cátia; Martins, M Rosário; Caldeira, A Teresa

    2015-02-01

    Different compounds of edible mushrooms are responsible for their bioactivity. The ability to synthesize polysaccharides, namely protein-polysaccharide (PPS) complexes, is related to the antioxidant capacity of these compounds and present great interest in preventing a number of diseases, including cancer, cardiovascular and auto-immune diseases, and accelerated aging. Amanita ponderosa are wild edible mushrooms that grow in Mediterranean "montado" areas [Portuguese name given to cork oak (Quercus suber) and holm oak (Quercus ilex) forests]. The aim of this study was to evaluate the production of PPS complexes obtained from A. ponderosa cultures using a new microanalytical approach to quickly and easily monitor the production process. Microanalysis using Fourier-transform infrared using attenuated total reflection and Raman spectroscopy of PPS samples showed spectra compatible with identification of this type of compound in culture extracts. PPS separated by size-exclusion chromatography showed seven main complexes. Molecular weights of the main PPS complexes isolated from cultures ranged between 1.5 and 20 kDa and did not present toxicity against Artemia salina, demonstrating the potential of A. ponderosa as a source of biologically active compounds with nutraceutical value. Application of this microanalytical approach to monitoring the production of PPS compounds can be successfully applied in biotechnological processes.

  1. Mechanisms of contextual risk for adolescent self-injury: invalidation and conflict escalation in mother-child interactions.

    PubMed

    Crowell, Sheila E; Baucom, Brian R; McCauley, Elizabeth; Potapova, Natalia V; Fitelson, Martha; Barth, Heather; Smith, Cindy J; Beauchaine, Theodore P

    2013-01-01

    According to developmental theories of self-injury, both child characteristics and environmental contexts shape and maintain problematic behaviors. Although progress has been made toward identifying biological vulnerabilities to self-injury, mechanisms underlying psychosocial risk have received less attention. In the present study, we compared self-injuring adolescents (n = 17) with typical controls (n = 20) during a mother-child conflict discussion. Dyadic interactions were coded using both global and microanalytic systems, allowing for a highly detailed characterization of mother-child interactions. We also assessed resting state psychophysiological regulation, as indexed by respiratory sinus arrhythmia (RSA). Global coding revealed that maternal invalidation was associated with adolescent anger. Furthermore, maternal invalidation and coerciveness were both related to adolescent opposition/defiance. Results from the microanalytic system indicated that self-injuring dyads were more likely to escalate conflict, suggesting a potential mechanism through which emotion dysregulation is shaped and maintained over time. Finally, mother and teen aversiveness interacted to predict adolescent resting RSA. Low-aversive teens with highly aversive mothers had the highest RSA, whereas teens in high-high dyads showed the lowest RSA. These findings are consistent with theories that emotion invalidation and conflict escalation are possible contextual risk factors for self-injury.

  2. Mechanisms of Contextual Risk for Adolescent Self-Injury: Invalidation and Conflict Escalation in Mother-Child Interactions

    PubMed Central

    Crowell, Sheila E.; Baucom, Brian R.; McCauley, Elizabeth; Potapova, Natalia V.; Fitelson, Martha; Barth, Heather; Smith, Cindy J.; Beauchaine, Theodore P.

    2013-01-01

    OBJECTIVE According to developmental theories of self-injury, both child characteristics and environmental contexts shape and maintain problematic behaviors. Although progress has been made toward identifying biological vulnerabilities to self-injury, mechanisms underlying psychosocial risk have received less attention. METHOD In the present study, we compared self-injuring adolescents (n=17) with typical controls (n=20) during a mother-child conflict discussion. Dyadic interactions were coded using both global and microanalytic systems, allowing for a highly detailed characterization of mother-child interactions. We also assessed resting state psychophysiological regulation, as indexed by respiratory sinus arrhythmia (RSA). RESULTS Global coding revealed that maternal invalidation was associated with adolescent anger. Furthermore, maternal invalidation and coerciveness were both related to adolescent opposition/defiance. Results from the microanalytic system indicated that self-injuring dyads were more likely to escalate conflict, suggesting a potential mechanism through which emotion dysregulation is shaped and maintained over time. Finally, mother and teen aversiveness interacted to predict adolescent resting RSA. Low-aversive teens with highly aversive mothers had the highest RSA, whereas teens in high-high dyads showed the lowest RSA. CONCLUSIONS These findings are consistent with theories that emotion invalidation and conflict escalation are possible contextual risk factors for self-injury. PMID:23581508

  3. Postvaccinal sarcomas in the cat: epidemiology and electron probe microanalytical identification of aluminum

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hendrick, M.J.; Goldschmidt, M.H.; Shofer, F.S.

    1992-10-01

    An increase in fibrosarcomas in a biopsy population of cats in the Pennsylvania area appears to be related to the increased vaccination of cats following enactment of a mandatory rabies vaccination law. The majority of fibrosarcomas arose in sites routinely used by veterinarians for vaccination, and 42 of 198 tumors were surrounded by lymphocytes and macrophages containing foreign material identical to that previously described in postvaccinal inflammatory injection site reactions. Some of the vaccines used have aluminum-based adjuvants, and macrophages surrounding three tumors contained aluminum oxide identified by electron probe microanalysis and imaged by energy-filtered electron microscopy. Persistence of inflammatorymore » and immunological reactions associated with aluminum may predispose the cat to a derangement of its fibrous connective tissue repair response, leading to neoplasia.« less

  4. NENIMF: Northeast National Ion Microprobe Facility - A Multi-User Facility for SIMS Microanalysis

    NASA Astrophysics Data System (ADS)

    Layne, G. D.; Shimizu, N.

    2002-12-01

    The MIT-Brown-Harvard Regional Ion Microprobe Facility was one of the earliest multi-user facilities enabled by Dan Weill's Instrumentation and Facilities Program - and began with the delivery of a Cameca IMS 3f ion microprobe to MIT in 1978. The Northeast National Ion Microprobe Facility (NENIMF) is the direct descendant of this original facility. Now housed at WHOI, the facility incorporates both the original IMS 3f, and a new generation, high transmission-high resolution instrument - the Cameca IMS 1270. Purchased with support from NSF, and from a consortium of academic institutions in the Northeast (The American Museum of Natural History, Brown University, The Lamont-Doherty Earth Observatory, MIT, Rensselaer Polytechnic Institute, WHOI) - this latest instrument was delivered and installed during 1996. NENIMF continues to be supported by NSF EAR I&F as a multi-user facility for geochemical research. Work at NENIMF has extended the original design strength of the IMS 1270 for microanalytical U-Pb zircon geochronology to a wide variety of novel and improved techniques for geochemical research. Isotope microanalysis for studies in volcanology and petrology is currently the largest single component of facility activity. This includes the direct measurement of Pb isotopes in melt inclusions, an application developed at NENIMF, which is making an increasingly significant contribution to our understanding of basalt petrogenesis. This same technique has also been extended to the determination of Pb isotopes in detrital feldspar grains, for the study of sedimentary provenance and tectonics of the Himalayas and other terrains. The determination of δ11B in volcanic melt inclusions has also proven to be a powerful tool in the modeling of subduction-related magmatism. The recent development of δ34S and δ37Cl determination in glasses is being applied to studies of the behavior of these volatile elements in both natural and experimental systems. Other recent undertakings have included development of high precision 232Th/230Th for U-series disequilibrium studies of young volcanic rocks, and the implementation and refinement of U-Th-Pb dating of individual monazite crystals. The facility is also developing an expanding number of applications in the general field of biogeochemistry. Examples include; δ18O in biogenic carbonates for climate and paleotemperature studies, determination of δ13C in graphite microfossils for early life studies, and determination of δ13C and trace metal concentrations in bacterial cultures in support of studies of natural microbial ecosystems. The IMS 3f instrument - now in its 25th year of operation - continues to be a productive resource for trace element and rare earth element determinations in natural and experimental materials. It has also become an important component of ongoing research in the derivation of paleotemperatures from marine biomineralization using trace element ratios of biogenic aragonite.

  5. Characterization and differentiation of rock varnish types from different environments by microanalytical techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Macholdt, D. S.; Jochum, K. P.; Pöhlker, C.

    We investigated rock varnishes collected from several locations and environments worldwide by a wide range of microanalytical techniques. These techniques were selected to address the challenges posed by the chemical and structural complexity within the micrometer- to nanometer-sized structures in these geological materials. Femtosecond laser ablation-inductively coupled plasma-mass spectrometry (fs LA-ICP-MS), scanning transmission X-ray microscopy-near edge X-ray adsorption fine structure spectroscopy (STXM-NEXAFS) in combination with scanning electron microscopy (SEM) of focused ion beam (FIB) ultra-thin (100–200 nm) sections, conventional and polarization microscopy, as well as electron paramagnetic resonance (EPR) measurements were used to obtain information about these rock varnishes. Rockmore » varnishes from different environments, which cannot readily be distinguished based on their macroscopic appearance, differ significantly in their constituent elemental mass fractions, e.g., of Mn, Fe, Ni, Co, Ba, and Pb, and their rare earth element (REE) patterns. Structural characteristics such as the particle sizes of embedded dust grains, internal structures such as layers of Mn-, Fe-, and Ca -rich material, and structures such as cavities varied between varnishes from different environments and regions in the world. The EPR spectra were consistent with aged biogenic Mn oxides in all samples, but showed subtle differences between samples of different origin. Our observations allow us to separate rock varnishes into different types, with differences that might be indicators of distinct geneses. Five different types of rock varnish could be distinguished, Type I–V, of which only Type I might be used as potential paleoclimate archive. Each varnish type has specific characteristics in terms of their elemental composition, element distribution, and structures. The combination of element ratios (Mn/Ba, Al/Ni, Mn/REY, Mn/Ce, Mn/Pb, La N /Yb N , and Ce/Ce*), total REE contents, and structures can be used to separate the different types of rock varnish from each other.« less

  6. Microanalytical identification of barium sulphate crystals in statoliths of Chara Rhizoids

    NASA Technical Reports Server (NTRS)

    Schroeter, K.; Lauchli, A.; Sievers, A. J.

    1979-01-01

    In contrast to higher plants, Chara rhizoids contain statolith vacuoles filled with biocrystallites of BaS04 in the form of rods composed of globular subunits ca. 7 nm in diameter. The revelation of the crystallites under electron microscopy is dependent on the fixative; best structural preservation was observed after fixation in a buffered glutaraldehyde + acrolein solution; 0s04 and KMnO4 partially dissolved both the biocrystallites and synthetic BaS04.

  7. Space Science

    NASA Image and Video Library

    2003-06-07

    The heart of a colorimetric solid phase extractor (CSPE) test kit quickly measures the concentration of the biocides silver or iodine in astronauts’ drinking water to determine whether concentrations are safe. When 10 milliliters (ml) of water is drawn through the disk, the disk will turn color (yellow in this picture for iodine) indicating the presence of the biocides. The device could someday be used to test water safety at reservoirs and water treatment plants on Earth. (photo credit: Microanalytical Instrumentation Center, Iowa State University).

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vilches, J.; Lopez, A.; Martinez, M.C.

    This paper discusses the value of scanning electron microscopy (SEM) and x-ray microanalysis in the classification of craniopharyngiomas. This neoplasm shows epithelial nest, cords of cuboid cells, foci of squamous metaplasia, and microcystic degeneration. SEM reveals that the epithelial cysts are lined with elongated cells that possess numerous microvilli and blebs and that some cysts are lined with polyhedral cells. The microvilli are interpreted as characteristic of the fast growing craniopharyngiomas. A microanalytical study of the calcified areas reveals the presence of magnesium, phosphorus, and calcium.

  9. Simultaneous X-ray fluorescence and scanning X-ray diffraction microscopy at the Australian Synchrotron XFM beamline

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, Michael W. M.; Phillips, Nicholas W.; van Riessen, Grant A.

    2016-08-11

    Owing to its extreme sensitivity, quantitative mapping of elemental distributionsviaX-ray fluorescence microscopy (XFM) has become a key microanalytical technique. The recent realisation of scanning X-ray diffraction microscopy (SXDM) meanwhile provides an avenue for quantitative super-resolved ultra-structural visualization. The similarity of their experimental geometries indicates excellent prospects for simultaneous acquisition. Here, in both step- and fly-scanning modes, robust, simultaneous XFM-SXDM is demonstrated.

  10. Analysis of defect structure in silicon. Characterization of samples from UCP ingot 5848-13C

    NASA Technical Reports Server (NTRS)

    Natesh, R.; Guyer, T.; Stringfellow, G. B.

    1982-01-01

    Statistically significant quantitative structural imperfection measurements were made on samples from ubiquitous crystalline process (UCP) Ingot 5848 - 13 C. Important trends were noticed between the measured data, cell efficiency, and diffusion length. Grain boundary substructure appears to have an important effect on the conversion efficiency of solar cells from Semix material. Quantitative microscopy measurements give statistically significant information compared to other microanalytical techniques. A surface preparation technique to obtain proper contrast of structural defects suitable for QTM analysis was perfected.

  11. Morphological classification and microanalysis of tire tread particles worn by abrasion or corrosion

    NASA Astrophysics Data System (ADS)

    Crosta, Giovanni F.

    2011-06-01

    Two types of tread wear particles are investigated: tread wear particles from a steel brush abrader (TrBP) and particles produced during a steering pad run (TrSP). A leaching experiment in water at pH = 7.5 for 24 and 48h was carried out on TrBP to simulate environmental degradation. Images of all materials were collected by a scanning electron microscope (SEM) together with element microanalytical (EDX) data. Surface morphology is described by a function of wave number (the "enhanced spectrum") obtained from SEM image analysis and non-linear filtering. A surface roughness index, ρ, is derived from the enhanced spectrum. The innovative contribution of this work is the representation of morphology by means of ρ, which, together with EDX data, allows the quantitative characterization of the materials. In particular, the surface roughness of leached TrBP is shown to decay in time and is related to the corresponding microanalytical data for the first time. The morphology of steering pad TrSP, affected by included mineral particles, is shown to be more heterogeneous. Differences in morphology (enhanced spectra and ρ), elemental composition and surface chemistry of TrBP and TrSP are discussed. All methods described and implemented herewith can be immediately applied to other types of tread wear material. The arguments put forward herewith should help in the proper design of those experiments aimed at assessing the impact of tread wear materials on the environment and on human health.

  12. Electroosmotic pumps for microflow analysis

    PubMed Central

    Wang, Xiayan; Wang, Shili; Gendhar, Brina; Cheng, Chang; Byun, Chang Kyu; Li, Guanbin; Zhao, Meiping; Liu, Shaorong

    2009-01-01

    With rapid development in microflow analysis, electroosmotic pumps are receiving increasing attention. Compared to other micropumps, electroosmotic pumps have several unique features. For example, they are bi-directional, can generate constant and pulse-free flows with flow rates well suited to microanalytical systems, and can be readily integrated with lab-on-chip devices. The magnitude and the direction of flow of an electroosmotic pump can be changed instantly. In addition, electroosmotic pumps have no moving parts. In this article, we discuss common features, introduce fabrication technologies and highlight applications of electroosmotic pumps. PMID:20047021

  13. Non-planar chemical preconcentrator

    DOEpatents

    Manginell, Ronald P [Albuquerque, NM; Adkins, Douglas R [Albuquerque, NM; Sokolowski, Sara S [Albuquerque, NM; Lewis, Patrick R [Albuquerque, NM

    2006-10-10

    A non-planar chemical preconcentrator comprises a high-surface area, low mass, three-dimensional, flow-through sorption support structure that can be coated or packed with a sorptive material. The sorptive material can collect and concentrate a chemical analyte from a fluid stream and rapidly release it as a very narrow temporal plug for improved separations in a microanalytical system. The non-planar chemical preconcentrator retains most of the thermal and fabrication benefits of a planar preconcentrator, but has improved ruggedness and uptake, while reducing sorptive coating concerns and extending the range of collectible analytes.

  14. Sub-to super-ambient temperature programmable microfabricated gas chromatography column

    DOEpatents

    Robinson, Alex L.; Anderson, Lawrence F.

    2004-03-16

    A sub- to super-ambient temperature programmable microfabricated gas chromatography column enables more efficient chemical separation of chemical analytes in a gas mixture by combining a thermoelectric cooler and temperature sensing on the microfabricated column. Sub-ambient temperature programming enables the efficient separation of volatile organic compounds and super-ambient temperature programming enables the elution of less volatile analytes within a reasonable time. The small heat capacity and thermal isolation of the microfabricated column improves the thermal time response and power consumption, both important factors for portable microanalytical systems.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vilches, J.; Lopez, A.; De Palacio, L.

    Calculi removed from human prostates affected with nodular hyperplasia were analyzed with scanning electron microscopy and EDAX system. The general spectrum was made up of Na, Al, Mg, S, P, Ca and Zn. Two types of stone were identified morphostructurally and microanalytically: calculi type I of nodular surface with high peaks of S, and calculi type II polyfaceted with high peaks of P and Ca. Their formation from corpora amylacea and/or exogenous constituents is discussed. The superficial deposit of Zn suggests its incorporation from the prostatic liquid and does not seem to play an important role in the genesis.

  16. Cometary and interstellar dust grains - Analysis by ion microprobe mass spectrometry and other techniques

    NASA Technical Reports Server (NTRS)

    Zinner, Ernst

    1991-01-01

    A survey of microanalytical measurements on interplanetary dust particles (IDPs) and interstellar dust grains from primitive meteorites is presented. Ion-microprobe mass spectrometry with its capability to determine isotopic compositions of many elements on a micron spatial scale has played a special role. Examples are measurements of H, N, and O isotopes and refractory trace elements in IDPs; C, N, Mg, and Si isotopes in interstellar SiC grains; and C and N isotopes and H, N, Al, and Si concentrations in interstellar graphite grains.

  17. Synthesis, spectral characterization and antimicrobial studies of nano-sized oxovanadium(IV) complexes with Schiff bases derived from 5-(phenyl/substituted phenyl)-2-hydrazino-1,3,4-thiadiazole and indoline-2,3-dione.

    PubMed

    Sahani, M K; Yadava, U; Pandey, O P; Sengupta, S K

    2014-05-05

    A new class of oxovanadium(IV) complexes with Schiff bases derived by the condensation of 5-(phenyl/substituted phenyl)-2-hydrazino-1,3,4-thiadiazoles and indoline-2,3-dione have been prepared in ethanol in the presence of sodium acetate. Micro-analytical data, magnetic susceptibility, UV-Vis, IR, EPR and XRD spectral techniques were used to confirm the structures. Electronic absorption spectra of the complexes suggest a square-pyramidal geometry. The oxovanadium(IV) complexes have monoclinic crystal system and particle sizes were found to be in the range 18.0 nm to 24.0 nm (nano-size). In vitro antifungal activity of synthesized compounds was determined against fungi Aspergillus niger, Colletotrichum falcatum and Colletotrichum pallescence and in vitro antibacterial activity was determined by screening the compounds against Gram-negative (Escherichia coli and Salmonella typhi) and Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacterial strains. The oxovanadium(IV) complexes have higher antimicrobial effect than free ligands. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Spectral, biological screening of metal chelates of chalcone based Schiff bases of N-(3-aminopropyl) imidazole.

    PubMed

    Kalanithi, M; Rajarajan, M; Tharmaraj, P; Sheela, C D

    2012-02-15

    Tridentate chelate complexes of Co(II), Ni(II), Cu(II) and Zn(II) have been synthesized from the chalcone based ligands 2-[1-(3-(1H-imidazol-1-yl)propylimino)-3-(phenylallyl)]phenol(HL(1)), 2-[1-(3-(1H-imidazol-1-yl)propylimino)-3-p-tolylallyl]phenol(HL(2)), 2-[1-(3-(1H-imidazol-1-yl)propylimino)-3-4-nitrophenylallyl]phenol(HL(3)). Microanalytical data, UV-vis spectrophotometric method, magnetic susceptibility measurements, IR, 1H NMR, Mass, and EPR techniques were used to characterize the structure of chelates. The electronic absorption spectra and magnetic susceptibility measurements suggest a distorted square planar geometry for the copper(II) ion. The other metal complexes show distorted tetrahedral geometry. The coordination of the ligands with metal(II) ions was further confirmed by solution fluorescence spectrum. The antimicrobial activity of the ligands and metal(II) complexes against the species Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Candida albigans and Aspergillus niger has been carried out and compared. The electrochemical behavior of copper(II) complex is studied by cyclic voltammetry. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. Characterisation of a natural quartz crystal as a reference material for microanalytical determination of Ti, Al, Li, Fe, Mn, Ga and Ge

    USGS Publications Warehouse

    Audetat, Andreas; Garbe-Schonberg, Dieter; Kronz, Andreas; Pettke, Thomas; Rusk, Brian G.; Donovan, John J.; Lowers, Heather

    2015-01-01

    A natural smoky quartz crystal from Shandong province, China, was characterised by laser ablation ICP-MS, electron probe microanalysis (EPMA) and solution ICP-MS to determine the concentration of twenty-four trace and ultra trace elements. Our main focus was on Ti quantification because of the increased use of this element for titanium-in-quartz (TitaniQ) thermobarometry. Pieces of a uniform growth zone of 9 mm thickness within the quartz crystal were analysed in four different LA-ICP-MS laboratories, three EPMA laboratories and one solution-ICP-MS laboratory. The results reveal reproducible concentrations of Ti (57 ± 4 μg g-1), Al (154 ± 15 μg g-1), Li (30 ± 2 μg g-1), Fe (2.2 ± 0.3 μg g-1), Mn (0.34 ± 0.04 μg g-1), Ge (1.7 ± 0.2 μg g-1) and Ga (0.020 ± 0.002 μg g-1) and detectable, but less reproducible, concentrations of Be, B, Na, Cu, Zr, Sn and Pb. Concentrations of K, Ca, Sr, Mo, Ag, Sb, Ba and Au were below the limits of detection of all three techniques. The uncertainties on the average concentration determinations by multiple techniques and laboratories for Ti, Al, Li, Fe, Mn, Ga and Ge are low; hence, this quartz can serve as a reference material or a secondary reference material for microanalytical applications involving the quantification of trace elements in quartz.

  20. The effects of strontium on bone mineral: A review on current knowledge and microanalytical approaches.

    PubMed

    Querido, William; Rossi, Andre L; Farina, Marcos

    2016-01-01

    The interest in effects of strontium (Sr) on bone has greatly increased in the last decade due to the development of the promising drug strontium ranelate. This drug is used for treating osteoporosis, a major bone disease affecting hundreds of millions of people worldwide, especially postmenopausal women. The novelty of strontium ranelate compared to other treatments for osteoporosis is its unique effect on bone: it simultaneously promotes bone formation by osteoblasts and inhibits bone resorption by osteoclasts. Besides affecting bone cells, treatment with strontium ranelate also has a direct effect on the mineralized bone matrix. Due to the chemical similarities between Sr and Ca, a topic that has long been of particular interest is the incorporation of Sr into bones replacing Ca from the mineral phase, which is composed by carbonated hydroxyapatite nanocrystals. Several groups have analyzed the mineral produced during treatment; however, most analysis were done with relatively large samples containing numerous nanocrystals, resulting thus on data that represents an average of many crystalline domains. The nanoscale analysis of the bone apatite crystals containing Sr has only been described in a few studies. In this study, we review the current knowledge on the effects of Sr on bone mineral and discuss the methodological approaches that have been used in the field. In particular, we focus on the great potential that advanced microscopy and microanalytical techniques may have on the detailed analysis of the nanostructure and composition of bone apatite nanocrystals produced during treatment with strontium ranelate. Copyright © 2015. Published by Elsevier Ltd.

  1. Correlated Raman micro-spectroscopy and scanning electron microscopy analyses of flame retardants in environmental samples: a micro-analytical tool for probing chemical composition, origin and spatial distribution.

    PubMed

    Ghosal, Sutapa; Wagner, Jeff

    2013-07-07

    We present correlated application of two micro-analytical techniques: scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS) and Raman micro-spectroscopy (RMS) for the non-invasive characterization and molecular identification of flame retardants (FRs) in environmental dusts and consumer products. The SEM/EDS-RMS technique offers correlated, morphological, molecular, spatial distribution and semi-quantitative elemental concentration information at the individual particle level with micrometer spatial resolution and minimal sample preparation. The presented methodology uses SEM/EDS analyses for rapid detection of particles containing FR specific elements as potential indicators of FR presence in a sample followed by correlated RMS analyses of the same particles for characterization of the FR sub-regions and surrounding matrices. The spatially resolved characterization enabled by this approach provides insights into the distributional heterogeneity as well as potential transfer and exposure mechanisms for FRs in the environment that is typically not available through traditional FR analysis. We have used this methodology to reveal a heterogeneous distribution of highly concentrated deca-BDE particles in environmental dust, sometimes in association with identifiable consumer materials. The observed coexistence of deca-BDE with consumer material in dust is strongly indicative of its release into the environment via weathering/abrasion of consumer products. Ingestion of such enriched FR particles in dust represents a potential for instantaneous exposure to high FR concentrations. Therefore, correlated SEM/RMS analysis offers a novel investigative tool for addressing an area of important environmental concern.

  2. [Early interaction is a prerequisite for favorable psychic development].

    PubMed

    Pesonen, Anu-Katriina

    2010-01-01

    Empirical studies on the parent-baby interaction have greatly influenced our insight into the child's psychological development. Initial stages of the research attempted to reveal features in the mother's action that would predict the child's favorable development. Since then, also fathers and the child's development in a more broad sense have been studied. The most prominent progress has taken place in microanalytical methods for these interactions. The research has increased our knowledge of the baby's interactive capabilities and the significance of successful interactive events for the child's development, laying the basis for various interventions related to parenthood.

  3. Workshop on Analysis of Returned Comet Nucleus Samples

    NASA Technical Reports Server (NTRS)

    1989-01-01

    This volume contains abstracts that were accepted by the Program Committee for presentation at the workshop on the analysis of returned comet nucleus samples held in Milpitas, California, January 16 to 18, 1989. The abstracts deal with the nature of cometary ices, cryogenic handling and sampling equipment, origin and composition of samples, and spectroscopic, thermal and chemical processing methods of cometary nuclei. Laboratory simulation experimental results on dust samples are reported. Some results obtained from Halley's comet are also included. Microanalytic techniques for examining trace elements of cometary particles, synchrotron x ray fluorescence and instrument neutron activation analysis (INAA), are presented.

  4. Microanalytical study of some cosmic dust discovered in sea-floor sediments in China

    NASA Technical Reports Server (NTRS)

    Shijie, Z.; Hanchang, P.; Zhong, Y.

    1984-01-01

    The study of cosmic dust can provide useful data in the investigation of the origin of the Earth and the evolution of celestial bodies. Three types of cosmic dust (ferriginous, siliceous, and glassy) were discovered in the seafloor sediments near China. Their chemical composition and microstructure were examined by X-ray diffraction, fractography, and electron microscopy. The major mineral in an iron-containing cosmic dust is magnetite. The silicate spheres contain sundry metals and metal oxides. Glassy microtektites are similar in composition to tektites, and are found in all the major meteorite areas worldwide.

  5. Considering "Nonlinearity" Across the Continuum in Medical Education Assessment: Supporting Theory, Practice, and Future Research Directions.

    PubMed

    Durning, Steven J; Lubarsky, Stuart; Torre, Dario; Dory, Valérie; Holmboe, Eric

    2015-01-01

    The purpose of this article is to propose new approaches to assessment that are grounded in educational theory and the concept of "nonlinearity." The new approaches take into account related phenomena such as "uncertainty," "ambiguity," and "chaos." To illustrate these approaches, we will use the example of assessment of clinical reasoning, although the principles we outline may apply equally well to assessment of other constructs in medical education. Theoretical perspectives include a discussion of script theory, assimilation theory, self-regulated learning theory, and situated cognition. Assessment examples to include script concordance testing, concept maps, self-regulated learning microanalytic technique, and work-based assessment, which parallel the above-stated theories, respectively, are also highlighted. We conclude with some practical suggestions for approaching nonlinearity. © 2015 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on Continuing Medical Education, Association for Hospital Medical Education.

  6. Australian Red Dune Sand: A Potential Martian Regolith Analog

    NASA Technical Reports Server (NTRS)

    Kuhlman, K. R.; Marshall, J.; Evans, N. D.; Luttge, A.

    2001-01-01

    To demonstrate the potential scientific and technical merits of in situ microscopy on Mars, we analyzed a possible Martian regolith analog - an acolian red dune sand from the central Australian desert (near Mt. Olga). This sand was chosen for its ubiquitous red coating and the desert environment in which is it found. Grains of this sand were analyzed using a variety of microanalytical techniques. A database of detailed studies of such terrestrial analogs would assist the study of geological and astrobiological specimens in future missions to Mars. Potential instrument concepts for in situ deployment on Mars include local electrode atom probe nanoanalysis (LEAP), vertical scanning white light interferometry (VSWLI), scanning electron microscopies, energy dispersive x-ray microanalysis (EDX), atomic force microscopy (AFM) and X-ray diffraction (XRD). While in situ deployment of these techniques is many years away, ground-based studies using these analytical techniques extend our understanding of the data obtained from instruments to be flown in the near future.

  7. High-Performance and Traditional Multicrystalline Silicon: Comparing Gettering Responses and Lifetime-Limiting Defects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Castellanos, Sergio; Ekstrom, Kai E.; Autruffe, Antoine

    2016-05-01

    In recent years, high-performance multicrystalline silicon (HPMC-Si) has emerged as an attractive alternative to traditional ingot-based multicrystalline silicon (mc-Si), with a similar cost structure but improved cell performance. Herein, we evaluate the gettering response of traditional mc-Si and HPMC-Si. Microanalytical techniques demonstrate that HPMC-Si and mc-Si share similar lifetime-limiting defect types but have different relative concentrations and distributions. HPMC-Si shows a substantial lifetime improvement after P-gettering compared with mc-Si, chiefly because of lower area fraction of dislocation-rich clusters. In both materials, the dislocation clusters and grain boundaries were associated with relatively higher interstitial iron point-defect concentrations after diffusion, which ismore » suggestive of dissolving metal-impurity precipitates. The relatively fewer dislocation clusters in HPMC-Si are shown to exhibit similar characteristics to those found in mc-Si. Given similar governing principles, a proxy to determine relative recombination activity of dislocation clusters developed for mc-Si is successfully transferred to HPMC-Si.« less

  8. Compound Nucleus Reactions in LENR, Analogy to Uranium Fission

    NASA Astrophysics Data System (ADS)

    Hora, Heinrich; Miley, George; Philberth, Karl

    2008-03-01

    The discovery of nuclear fission by Hahn and Strassmann was based on a very rare microanalytical result that could not initially indicate the very complicated details of this most important process. A similarity is discussed for the low energy nuclear reactions (LENRs) with analogies to the yield structure found in measurements of uranium fission. The LENR product distribution measured earlier in a reproducible way in experiments with thin film electrodes and a high density deuteron concentration in palladium has several striking similarities with the uranium fission fragment yield curve.ootnotetextG.H. Miley and J.A. Patterson, J. New Energy 1, 11 (1996); G.H. Miley et al, Proc ICCF6, p. 629 (1997).This comparison is specifically focussed to the Maruhn-Greiner local maximum of the distribution within the large-scale minimum when the fission nuclei are excited. Implications for uranium fission are discussed in comparison with LENR relative to the identification of fission a hypothetical compound nuclear reaction via a element ^306X126 with double magic numbers.

  9. Sample displacement chromatography as a method for purification of proteins and peptides from complex mixtures

    PubMed Central

    Gajdosik, Martina Srajer; Clifton, James; Josic, Djuro

    2012-01-01

    Sample displacement chromatography (SDC) in reversed-phase and ion-exchange modes was introduced approximately twenty years ago. This method takes advantage of relative binding affinities of components in a sample mixture. During loading, there is a competition among different sample components for the sorption on the surface of the stationary phase. SDC was first used for the preparative purification of proteins. Later, it was demonstrated that this kind of chromatography can also be performed in ion-exchange, affinity and hydrophobic-interaction mode. It has also been shown that SDC can be performed on monoliths and membrane-based supports in both analytical and preparative scale. Recently, SDC in ion-exchange and hydrophobic interaction mode was also employed successfully for the removal of trace proteins from monoclonal antibody preparations and for the enrichment of low abundance proteins from human plasma. In this review, the principals of SDC are introduced, and the potential for separation of proteins and peptides in micro-analytical, analytical and preparative scale is discussed. PMID:22520159

  10. Combined oxygen-isotope and U-Pb zoning studies of titanite: New criteria for age preservation

    DOE PAGES

    Bonamici, Chloe E.; Fanning, C. Mark; Kozdon, Reinhard; ...

    2015-02-11

    Here, titanite is an important U-Pb chronometer for dating geologic events, but its high-temperature applicability depends upon its retention of radiogenic lead (Pb). Experimental data predict similar rates of diffusion for lead (Pb) and oxygen (O) in titanite at granulite-facies metamorphic conditions (T = 650-800°C). This study therefore investigates the utility of O-isotope zoning as an indicator for U-Pb zoning in natural titanite samples from the Carthage-Colton Mylonite Zone of the Adirondack Mountains, New York. Based on previous field, textural, and microanalytical work, there are four generations (types) of titanite in the study area, at least two of which preservemore » diffusion-related δ 18O zoning. U-Th-Pb was analyzed by SIMS along traverses across three grains of type-2 titanite, which show well-developed diffusional δ 18O zoning, and one representative grain from each of the other titanite generations.« less

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rodríguez-Pulido, A.; Martínez-Gutiérrez, H.; Calderon-Polania, G. A.

    Nitrogen-doped multiwalled carbon nanotubes (CNx-MWNTs) have been decorated with γ-Al 2O 3 nanoparticles by a novel method. This process involved a wet chemical approach in conjunction with thermal treatment. During the particle anchoring process, individual CNx-MWNT nanotubes agglomerated into bundles, resulting in arrays of aligned CNx-MWNT coated with γ-Al 2O 3. Extensive characterization of the resulting γ-Al 2O 3/CNx-MWNT bundles was performed using a range of electron microscopy imaging and microanalytical techniques. In conclusion, a possible mechanism explaining the nanobundle alignment is described, and possible applications of these materials for the fabrication of ceramic composites using CNx-MWNTs are briefly discussed.

  12. Formation of hydrogen peroxide in the silver reductor: A micro-analytical method for iron

    USGS Publications Warehouse

    Fryling, C.F.; Tooley, F.V.

    1936-01-01

    1. An attempt to determine small quantities of iron by reduction with silver followed by titration with eerie sulfate revealed an error attributable to the formation of hydrogen peroxide in the reductor. 2. By conducting the reduction in an atmosphere of hydrogen, thereby decreasing the reductor correction, and applying a correction for the indicator, it was possible to determine quantities of iron of the order of 1.5 mg. with a high degree of accuracy. 3. The method was found to be relatively rapid and not to require the use of large platinum dishes, thus possessing advantages of practical value.

  13. Advances toward submicron resolution optics for x-ray instrumentation and applications

    NASA Astrophysics Data System (ADS)

    Cordier, Mark; Stripe, Benjamin; Yun, Wenbing; Lau, S. H.; Lyon, Alan; Reynolds, David; Lewis, Sylvia J. Y.; Chen, Sharon; Semenov, Vladimir A.; Spink, Richard I.; Seshadri, Srivatsan

    2017-08-01

    Sigray's axially symmetric x-ray optics enable advanced microanalytical capabilities for focusing x-rays to microns-scale to submicron spot sizes, which can potentially unlock many avenues for laboratory micro-analysis. The design of these optics allows submicron spot sizes even at low x-ray energies, enabling research into low atomic number elements and allows increased sensitivity of grazing incidence measurements and surface analysis. We will discuss advances made in the fabrication of these double paraboloidal mirror lenses designed for use in laboratory x-ray applications. We will additionally present results from as-built paraboloids, including surface figure error and focal spot size achieved to-date.

  14. Development of Austenitic ODS Strengthened Alloys for Very High Temperature Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stubbins, James; Heuser, Brent; Robertson, Ian

    2015-04-22

    This “Blue Sky” project was directed at exploring the opportunities that would be gained by developing Oxide Dispersion Strengthened (ODS) alloys based on the Fe-Cr-Ni austenitic alloy system. A great deal of research effort has been directed toward ferritic and ferritic/martensitic ODS alloys which has resulted in reasonable advances in alloy properties. Similar gains should be possible with austenitic alloy which would also take advantage of other superior properties of that alloy system. The research effort was aimed at the developing an in-depth understanding of the microstructural-level strengthening effects of ODS particles in austentic alloys. This was accomplished on amore » variety of alloy compositions with the main focus on 304SS and 316SS compositions. A further goal was to develop an understanding other the role of ODS particles on crack propagation and creep performance. Since these later two properties require bulk alloy material which was not available, this work was carried out on promising austentic alloy systems which could later be enhanced with ODS strengthening. The research relied on a large variety of micro-analytical techniques, many of which were available through various scientific user facilities. Access to these facilities throughout the course of this work was instrumental in gathering complimentary data from various analysis techniques to form a well-rounded picture of the processes which control austenitic ODS alloy performance. Micromechanical testing of the austenitic ODS alloys confirmed their highly superior mechanical properties at elevated temperature from the enhanced strengthening effects. The study analyzed the microstructural mechanisms that provide this enhanced high temperature performance. The findings confirm that the smallest size ODS particles provide the most potent strengthening component. Larger particles and other thermally- driven precipitate structures were less effective contributors and, in some cases, limited overall properties. With this understanding, the major materials development challenge is to provide a high uniformly distributed population of very fine ODS particles to be able to realize the full promise of dispersion strengthening. This should be a major goal of future work. This program had the further goal to develop graduate student researcher with the experience and capabilities to move this field forward. The support in this program was used for graduate student support and for research expenses; none of the program funds directly supported the faculty in the program. In this sense, the program was successful in supporting several very promising graduate researchers. Four of the graduate students supported here will complete their PhDs in 2015.« less

  15. Geochemical and mineralogical controls on metal(loid) mobility in the oxide zone of the Prairie Creek Deposit, NWT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stavinga, Drew; Jamieson, Heather; Layton-Matthews, Daniel

    2017-02-01

    Prairie Creek is an unmined high grade Zn-Pb-Ag deposit in the southern Mackenzie Mountains of the Northwest Territories, located in a 320 km2 enclave surrounded by the Nahanni National Park reserve. The upper portion of the quartz-carbonate-sulphide vein mineralization has undergone extensive oxidation, forming high grade zones, rich in smithsonite (ZnCO3) and cerussite (PbCO3). This weathered zone represents a significant resource and a potential component of mine waste material. This study is focused on characterizing the geochemical and mineralogical controls on metal(loid) mobility under mine waste conditions, with particular attention to the metal carbonates as a potential source of tracemore » elements to the environment. Analyses were conducted using a combination of microanalytical techniques (electron microprobe, scanning electron microscopy with automated mineralogy, laser-ablation inductively-coupled mass spectrometry, and synchrotron-based element mapping, micro-X-ray diffraction and micro-X-ray absorbance). The elements of interest included Zn, Pb, Ag, As, Cd, Cu, Hg, Sb and Se.« less

  16. Study of Chemical Changes in Uranium Oxyfluoride Particles Progress Report March - October 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kips, R; Kristo, M; Hutcheon, I

    2009-11-22

    Nuclear forensics relies on the analysis of certain sample characteristics to determine the origin and history of a nuclear material. In the specific case of uranium enrichment facilities, it is the release of trace amounts of uranium hexafluoride (UF{sub 6}) gas - used for the enrichment of uranium - that leaves a process-characteristic fingerprint. When UF{sub 6} gas interacts with atmospheric moisture, uranium oxyfluoride particles or particle agglomerates are formed with sizes ranging from several microns down to a few tens of nanometers. These particles are routinely collected by safeguards organizations, such as the International Atomic Energy Agency (IAEA), allowingmore » them to verify whether a facility is compliant with its declarations. Spectrometric analysis of uranium particles from UF{sub 6} hydrolysis has revealed the presence of both particles that contain fluorine, and particles that do not. It is therefore assumed that uranium oxyfluoride is unstable, and decomposes to form uranium oxide. Understanding the rate of fluorine loss in uranium oxyfluoride particles, and the parameters that control it, may therefore contribute to placing boundaries on the particle's exposure time in the environment. Expressly for the purpose of this study, we prepared a set of uranium oxyfluoride particles at the Institute for Reference Materials and Measurements (EU-JRC-IRMM) from a static release of UF{sub 6} in a humid atmosphere. The majority of the samples was stored in controlled temperature, humidity and lighting conditions. Single particles were characterized by a suite of micro-analytical techniques, including NanoSIMS, micro-Raman spectrometry (MRS), scanning (SEM) and transmission (TEM) electron microscopy, energy-dispersive X-ray spectrometry (EDX) and focused ion beam (FIB). The small particle size was found to be the main analytical challenge. The relative amount of fluorine, as well as the particle chemical composition and morphology were determined at different stages in the ageing process, and immediately after preparation. This report summarizes our most recent findings for each of the analytical techniques listed above, and provides an outlook on what remains to be resolved. Additional spectroscopic and mass spectrometric measurements were carried out at Pacific Northwest National Laboratory, but are not included in this summary.« less

  17. The epididymal microenvironment: a site of attack for a male contraceptive?

    PubMed

    Hinton, B T

    1980-07-01

    During their development, spermatozoa are continually bathed in fluid provided by epithelial secretions of the seminiferous tubule and the epididymal duct. This fluid or microenvironment is probably very important for spermatozoal maturation and survival. Micropuncture and microanalytic studies have revealed the occurrence of several biochemical changes of this specialized microenvironment along the epididymal duct; these changes seem to be linked to sperm maturation. The interactions between maturing spermatozoa and their microenvironment must be understood before interference in sperm maturation through intervention of the formation of the microenvironment is possible. Several compounds have been shown to interfere in spermatozoal maturation in the epididymis although their use as male contraceptives requires further investigation.

  18. Vital effects in coral skeletal composition display strict three-dimensional control

    USGS Publications Warehouse

    Meibom, A.; Yurimoto, H.; Cuif, J.-P.; Domart-Coulon, I.; Houlbreque, F.; Constantz, B.; Dauphin, Y.; Tambutte, E.; Tambutte, S.; Allemand, D.; Wooden, J.; Dunbar, R.

    2006-01-01

    Biological control over coral skeletal composition is poorly understood but critically important to paleoenvironmental reconstructions. We present microanalytical measurements of trace-element abundances as well as oxygen and carbon isotopic compositions of individual skeletal components in the zooxanthellate coral Colpophyllia sp. Our data show that centers of calcification (COC) have higher trace element concentrations and distinctly lighter isotopic compositions than the fibrous components of the skeleton. These observations necessitate that COC and the fibrous skeleton are precipitated by different mechanisms, which are controlled by specialized domains of the calicoblastic cell-layer. Biological processes control the composition of the skeleton even at the ultra-structure level. Copyright 2006 by the American Geophysical Union.

  19. Anchorage of γ-Al 2O 3 nanoparticles on nitrogen-doped multiwalled carbon nanotubes

    DOE PAGES

    Rodríguez-Pulido, A.; Martínez-Gutiérrez, H.; Calderon-Polania, G. A.; ...

    2016-06-07

    Nitrogen-doped multiwalled carbon nanotubes (CNx-MWNTs) have been decorated with γ-Al 2O 3 nanoparticles by a novel method. This process involved a wet chemical approach in conjunction with thermal treatment. During the particle anchoring process, individual CNx-MWNT nanotubes agglomerated into bundles, resulting in arrays of aligned CNx-MWNT coated with γ-Al 2O 3. Extensive characterization of the resulting γ-Al 2O 3/CNx-MWNT bundles was performed using a range of electron microscopy imaging and microanalytical techniques. In conclusion, a possible mechanism explaining the nanobundle alignment is described, and possible applications of these materials for the fabrication of ceramic composites using CNx-MWNTs are briefly discussed.

  20. White spots on Smoke rings by Bruce Nauman: a case study on contemporary art conservation using microanalytical techniques.

    PubMed

    Mafalda, Ana Cardeira; da Câmara, Rodrigo Bettencourt; Strzelec, Patrick; Schiavon, Nick; Mirão, José; Candeias, António; Carvalho, Maria Luísa; Manso, Marta

    2015-02-01

    The artwork "Smoke Rings: Two Concentric Tunnels, Non-Communicating" by Bruce Nauman represents a case study of corrosion of a black patina-coated Al-alloy contemporary artwork. The main concern over this artwork was the widespread presence of white spots on its surface. Alloy substrate, patina, and white spots were characterized by means of energy-dispersive X-ray fluorescence and scanning electron microscopy with energy-dispersive spectroscopy. Alloy substrate was identified as an aluminum alloy 6,000 series Al-Si-Mg. Patina's identified composition confirmed the documentation provided by the atelier. Concerning the white spots, zircon particles were found on patina surface as external elements.

  1. Microanalytical characterization of multi-rare earth nanocrystalline magnets by TEM and APT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Y. Q.; Tang, W.; Miller, Michael K

    2006-01-01

    The partitioning behavior of various rare-earth (RE) elements during solidification and their segregation behavior at the grain boundaries were investigated in nanocrystalline (Y{sub 0.5}Dy{sub 0.5}{sub 2.2}Fe{sub 14}B and (Nd{sub 0.5}Y{sub 0.25}Dy{sub 0.25}){sub 1.8}Zr{sub 0.4}Co{sub 1.5}Fe{sub 12.5}B alloys by transmission electron microscopy and atom probe tomography. The best hard magnetic properties obtained are H{sub cj} = 22 kOe, B{sub r}=5.10 kG, and (BH){sub max} = 5.97 MG Oe for the Y-Dy-based alloy and H{sub cj}=10.6 kOe, B{sub r}=6.64 kG, and (BH){sub max}=9.56 MG Oe for the Y-Nd-Dy based alloy. The grain size of the Y-Dy based alloy was {approx} 50 nm.more » The Y-Nd-Dy based alloy had an overall finer, bimodal grain size. An intergranular (Y{sub 0.36}Dy{sub 0.64}){sub 6}Fe{sub 23} phase was detected in the Y-Dy based alloy. A uniform distribution of RE elements was found within the 2-14-1 grains in both alloys. The Y:(Dy+Nd) ratio in the Y-Nd-Dy alloy was lower than its nominal composition, indicating that the Y is segregating to grain boundaries or forming a second phase.« less

  2. Engineering of PDMS Surfaces for use in Microsystems for Capture and Isolation of Complex and Biomedically Important Proteins: Epidermal Growth Factor Receptor as a Model System

    PubMed Central

    Lowe, Aaron M.; Ozer, Byram H.; Wiepz, Gregory J.; Bertics, Paul J.; Abbott, Nicholas L.

    2009-01-01

    Elastomers based on poly(dimethylsiloxane) (PDMS) are promising materials for fabrication of a wide range of microanalytical systems due to their mechanical and optical properties and ease of processing. To date, however, quantitative studies that demonstrate reliable and reproducible methods for attachment of binding groups that capture complex receptor proteins of relevance to biomedical applications of PDMS microsystems have not been reported. Herein we describe methods that lead to the reproducible capture of a transmembrane protein, the human epidermal growth factor (EGF) receptor, onto PDMS surfaces presenting covalently immobilized antibodies for EGF receptor, and subsequent isolation of the captured receptor by mechanical transfer of the receptor onto a chemically functionalized surface of a gold film for detection. This result is particularly significant because the physical properties of transmembrane proteins make this class of proteins a difficult one to analyze. We benchmark the performance of antibodies to the human EGF receptor covalently immobilized on PDMS against the performance of the same antibodies physisorbed to conventional surfaces utilized in ELISA assays through the use of EGF receptor that was 32P-radiolabeled in its autophosphorylation domain. These results reveal that two pan-reactive antibodies for the EGF receptor (H11 and 111.6) and one phosphospecific EGF receptor antibody (pY1068) capture the receptor on both PDMS and ELISA plates. When using H11 antibody to capture EGF receptor and subsequent treatment with a stripping buffer (NaOH and sodium dodecylsulfate) to isolate the receptor, the signal-to-background obtained using the PDMS surface was 82:1, exceeding the signal-to-background measured on the ELISA plate (<48:1). We also characterized the isolation of captured EGF receptor by mechanical contact of the PDMS surface with a chemically functionalized gold film. The efficiency of mechanical transfer of the transmembrane protein from the PDMS surface was found to be 75–81%. However, the transfer of non-specifically bound protein was substantially less than 75%, thus leading to the important finding that mechanical transfer of the EGF receptor leads to an approximately four-fold increase in signal-to-background from 20:1 to 88:1. The signal-to-background obtained following mechanical transfer is also better than that obtained using ELISA plates and stripping buffer (<48:1). The EGF receptor is a clinically important protein and the target of numerous anticancer agents and thus these results, when combined, provide guidance for the design of PDMS-based microanalytical systems for the capture and isolation of complex and clinically important transmembrane proteins. PMID:18651079

  3. Engineering of PDMS surfaces for use in microsystems for capture and isolation of complex and biomedically important proteins: epidermal growth factor receptor as a model system.

    PubMed

    Lowe, Aaron M; Ozer, Byram H; Wiepz, Gregory J; Bertics, Paul J; Abbott, Nicholas L

    2008-08-01

    Elastomers based on poly(dimethylsiloxane) (PDMS) are promising materials for fabrication of a wide range of microanalytical systems due to their mechanical and optical properties and ease of processing. To date, however, quantitative studies that demonstrate reliable and reproducible methods for attachment of binding groups that capture complex receptor proteins of relevance to biomedical applications of PDMS microsystems have not been reported. Herein we describe methods that lead to the reproducible capture of a transmembrane protein, the human epidermal growth factor (EGF) receptor, onto PDMS surfaces presenting covalently immobilized antibodies for EGF receptor, and subsequent isolation of the captured receptor by mechanical transfer of the receptor onto a chemically functionalized surface of a gold film for detection. This result is particularly significant because the physical properties of transmembrane proteins make this class of proteins a difficult one to analyze. We benchmark the performance of antibodies to the human EGF receptor covalently immobilized on PDMS against the performance of the same antibodies physisorbed to conventional surfaces utilized in ELISA assays through the use of EGF receptor that was (32)P-radiolabeled in its autophosphorylation domain. These results reveal that two pan-reactive antibodies for the EGF receptor (clones H11 and 111.6) and one phosphospecific EGF receptor antibody (clone pY1068) capture the receptor on both PDMS and ELISA plates. When using H11 antibody to capture EGF receptor and subsequent treatment with a stripping buffer (NaOH and sodium dodecylsulfate) to isolate the receptor, the signal-to-background obtained using the PDMS surface was 82 : 1, exceeding the signal-to-background measured on the ELISA plate (<48 : 1). We also characterized the isolation of captured EGF receptor by mechanical contact of the PDMS surface with a chemically functionalized gold film. The efficiency of mechanical transfer of the transmembrane protein from the PDMS surface was found to be 75-81%. However, the transfer of non-specifically bound protein was substantially less than 75%, thus leading to the important finding that mechanical transfer of the EGF receptor leads to an approximately four-fold increase in signal-to-background from 20 : 1 to 88 : 1. The signal-to-background obtained following mechanical transfer is also better than that obtained using ELISA plates and stripping buffer (<48 : 1). The EGF receptor is a clinically important protein and the target of numerous anticancer agents and thus these results, when combined, provide guidance for the design of PDMS-based microanalytical systems for the capture and isolation of complex and clinically important transmembrane proteins.

  4. From Dates to Rates: The Emergence of Integrated Geochronometry (Invited)

    NASA Astrophysics Data System (ADS)

    Hodges, K. V.; Adams, B. A.; Bohon, W.; Cooper, F. J.; Tripathy-Lang, A.; Van Soest, M. C.; Watson, E. B.; Young, K. E.

    2013-12-01

    Many applications of isotope geochemistry to telling time have involved geochronology - the measurement of the crystallization age of a mineral - or thermochronology, the measurement of the time at which a mineral cooled through an estimated closure temperature. The resulting data typically provide one or two points along an evolving temperature-time (Tt) path. Unfortunately, many problems require a richer knowledge of longer portions of the Tt path and thus the integrated application of multiple chronometers to individual minerals or suites of minerals from a particular sample or outcrop. In this presentation, we review some of the most recent advances in geochronometry, the direct dating of rates of a wide range of geologic processes on timescales ranging from seconds (in the case of bolide impact on Earth and elsewhere in the Solar System) to hundreds of millions of years (in the case of very slowly cooled Precambrian terrains). For all chronometers except those based on the production of fission tracks, our capacity to extract precise and accurate Tt paths depends on a good understanding of the kinetics of diffusive loss of radiogenic daughter isotopes. Laboratory experiments have substantially improved our understanding of nominal kinetic parameters in recent years, but our increased use of new methods for their determination (e.g., Rutherford backscattering spectroscopy, nuclear reaction analysis, and laser depth profiling) have demonstrated complexities related to compositional variations and asymmetric diffusion. At the same time, a growing number of geologic applications of these chronometers illustrate the importance of deformation history and radiation damage in modifying effective diffusion parameters. Such factors have two important implications for geochronometry. First, they suggest that studies of multiple minerals employing multiple isotopic methods - integrated geochronometry - are likely to produce more robust constraints on Tt paths than those involving the application of a single geochronometer. Second, they suggest that characterization of the chemistry and structure of minerals prior to dating may become standard procedure in most laboratories. Some of the most valuable constraints on the cooling histories of individual crystals come from microanalytical techniques that illuminate natural diffusive loss profiles, either directly (e.g., laser and ion microprobe mapping) or indirectly (e.g., 40Ar/39Ar and 4He/3He incremental heating experimentation). For most materials and most cooling histories, direct microanalytical approaches yield less spatial resolution and thus a poorer resolution of the cooling history. On the other hand, the extraction of cooling histories based on data obtained through indirect techniques requires significant simplifying assumptions regarding the three-dimensional distribution of parent isotopes that are not always warranted. Studies that integrate such techniques, rare in the literature thus far, are ushering in a new era of quantitative geochronometry.

  5. Photoresponse and DFT studies of new synthesized 2-benzylidene-3-hydroxy -1-(5,6-diphenyl-1,2,4-triazine-3-yl)hydrazine and optical sensor application

    NASA Astrophysics Data System (ADS)

    Taha, A.; Farag, A. A. M.; Adly, O. M. I.; Roushdy, N.; Shebl, Magdy; Ahmed, H. M.

    2017-08-01

    A newly Schiff base,2-benzylidene-3-hydroxy-1-(5,6-diphenyl-1,2,4-triazine-3-yl)hydrazine] (HBDHT) was synthesized and characterized on the basis of micro-analytical and spectroscopic studies. Basic parameters of the combined compound HBDHT were ascertained on the premise of DFT level actualized on Gaussian 09. Thin films of HBDHT were successfully prepared by spin coating technique and confirmed by atomic force microscopy (AFM). The optical attributes of the studied films were considered utilizing spectrophotometric estimations in a wide spectral range of 200-2500 nm. Some important optical parameters such as extinction index, refractive index, dispersion energy, oscillator energy and high-frequency dielectric constant were extracted. Analysis of the absorption coefficient near the fundamental absorption edge confirms an indirectly allowed transition with an energy gap of 1.7eV. The refractive index dispersion was estimated on basis of single oscillator model expressed by Wemple-Didomenico. Current-voltage (I-V) characteristics were studied in dark and under illumination of 100 mW/cm2 to clarify the sensitivity to light. Moreover, the photo-transient properties were also investigated to confirm that the prepared heterojunction based HBDHT can be operated as a photodiode.

  6. Insights into metals in individual fine particles from municipal solid waste using synchrotron radiation-based micro-analytical techniques.

    PubMed

    Zhu, Yumin; Zhang, Hua; Shao, Liming; He, Pinjing

    2015-01-01

    Excessive inter-contamination with heavy metals hampers the application of biological treatment products derived from mixed or mechanically-sorted municipal solid waste (MSW). In this study, we investigated fine particles of <2mm, which are small fractions in MSW but constitute a significant component of the total heavy metal content, using bulk detection techniques. A total of 17 individual fine particles were evaluated using synchrotron radiation-based micro-X-ray fluorescence and micro-X-ray diffraction. We also discussed the association, speciation and source apportionment of heavy metals. Metals were found to exist in a diffuse distribution with heterogeneous intensities and intense hot-spots of <10 μm within the fine particles. Zn-Cu, Pb-Fe and Fe-Mn-Cr had significant correlations in terms of spatial distribution. The overlapped enrichment, spatial association, and the mineral phases of metals revealed the potential sources of fine particles from size-reduced waste fractions (such as scraps of organic wastes or ceramics) or from the importation of other particles. The diverse sources of heavy metal pollutants within the fine particles suggested that separate collection and treatment of the biodegradable waste fraction (such as food waste) is a preferable means of facilitating the beneficial utilization of the stabilized products. Copyright © 2014. Published by Elsevier B.V.

  7. Exploring clinical reasoning in novices: a self-regulated learning microanalytic assessment approach

    PubMed Central

    Artino, Anthony R; Cleary, Timothy J; Dong, Ting; Hemmer, Paul A; Durning, Steven J

    2014-01-01

    Objectives The primary objectives of this study were to examine the regulatory processes of medical students as they completed a diagnostic reasoning task and to examine whether the strategic quality of these regulatory processes were related to short-term and longer-term medical education outcomes. Methods A self-regulated learning (SRL) microanalytic assessment was administered to 71 second-year medical students while they read a clinical case and worked to formulate the most probable diagnosis. Verbal responses to open-ended questions targeting forethought and performance phase processes of a cyclical model of SRL were recorded verbatim and subsequently coded using a framework from prior research. Descriptive statistics and hierarchical linear regression models were used to examine the relationships between the SRL processes and several outcomes. Results Most participants (90%) reported focusing on specific diagnostic reasoning strategies during the task (metacognitive monitoring), but only about one-third of students referenced these strategies (e.g. identifying symptoms, integration) in relation to their task goals and plans for completing the task. After accounting for prior undergraduate achievement and verbal reasoning ability, strategic planning explained significant additional variance in course grade (ΔR2 = 0.15, p < 0.01), second-year grade point average (ΔR2 = 0.14, p < 0.01), United States Medical Licensing Examination Step 1 score (ΔR2 = 0.08, p < 0.05) and National Board of Medical Examiner subject examination score in internal medicine (ΔR2 = 0.10, p < 0.05). Conclusions These findings suggest that most students in the formative stages of learning diagnostic reasoning skills are aware of and think about at least one key diagnostic reasoning process or strategy while solving a clinical case, but a substantially smaller percentage set goals or develop plans that incorporate such strategies. Given that students who developed more strategic plans achieved better outcomes, the potential importance of forethought regulatory processes is underscored. PMID:24528463

  8. Examining Middle School Science Student Self-Regulated Learning in a Hypermedia Learning Environment through Microanalysis

    NASA Astrophysics Data System (ADS)

    Mandell, Brian E.

    The purpose of the present embedded mixed method study was to examine the self-regulatory processes used by high, average, and low achieving seventh grade students as they learned about a complex science topic from a hypermedia learning environment. Thirty participants were sampled. Participants were administered a number of measures to assess their achievement and self-efficacy. In addition, a microanalytic methodology, grounded in Zimmerman's cyclical model of self-regulated learning, was used to assess student self-regulated learning. It was hypothesized that there would be modest positive correlations between Zimmerman's three phases of self-regulated learning, that high achieving science students would deploy more self-regulatory subprocesses than average and low achieving science students, that high achieving science students would have higher self-efficacy beliefs to engage in self-regulated learning than average and low achieving science students, and that low achieving science students would over-estimate their self-efficacy for performance beliefs, average achieving science students would slightly overestimate their self-efficacy for performance beliefs, and high achieving science students would under-estimate their self-efficacy for performance beliefs. All hypotheses were supported except for the high achieving science students who under-estimated their self-efficacy for performance beliefs on the Declarative Knowledge Measure and slightly overestimated their self-efficacy for performance beliefs on the Conceptual Knowledge Measure. Finally, all measures of self-regulated learning were combined and entered into a regression formula to predict the students' scores on the two science tests, and it was revealed that the combined measure predicted 91% of the variance on the Declarative Knowledge Measure and 92% of the variance on the Conceptual Knowledge Measure. This study adds hypermedia learning environments to the contexts that the microanalytic methodology has been successfully administered. Educational implications and limitations to the study are also discussed.

  9. A Development Strategy for Creating a Suite of Reference Materials for the in-situ Microanalysis of Non-conventional Raw Materials

    NASA Astrophysics Data System (ADS)

    Renno, A. D.; Merchel, S.; Michalak, P. P.; Munnik, F.; Wiedenbeck, M.

    2010-12-01

    Recent economic trends regarding the supply of rare metals readily justify scientific research into non-conventional raw materials, where a particular need is a better understanding of the relationship between mineralogy, microstructure and the distribution of key metals within ore deposits (geometallurgy). Achieving these goals will require an extensive usage of in-situ microanalytical techniques capable of spatially resolving material heterogeneities which can be key for understanding better resource utilization. The availability of certified reference materials (CRMs) is an essential prerequisite for (1) validating new analytical methods, (2) demonstrating data quality to the contracting authorities, (3) supporting method development and instrument calibration, and (4) establishing traceability between new analytical approaches and existing data sets. This need has led to the granting of funding by the European Union and the German Free State of Saxony for a program to develop such reference materials . This effort will apply the following strategies during the selection of the phases: (1) will use exclusively synthetic minerals, thereby providing large volumes of homogeneous starting material. (2) will focus on matrices which are capable of incorporating many ‘important’ elements while avoid exotic compositions which would not be optimal matrix matches. (3) will emphasise those phases which remain stable during the various microanalytical procedure. This initiative will assess the homogeneity of the reference materials at sampling sizes ranging between 50 and 1 µm; it is also intended to document crystal structural homogeneity too, as this too may potentially impact specific analytical methods. As far as possible both definitive methods as well as methods involving matrix corrections will be used for determining the compositions of the of the individual materials. A critical challenge will be the validation of the determination of analytes concentrations as sub-µg sampling masses. It is planned to cooperate with those who are interested in the development of such reference materials and we invite them to take part in round-robin exercises.

  10. Fabrication of functional devices using soft lithography and unconventional micropatterning

    NASA Astrophysics Data System (ADS)

    Deng, Tao

    In this thesis, I present part of our work in the fabrication of functional devices using soft lithography, and also describe unconventional micropatterning techniques involving photographic films. Soft lithography is a set of techniques that are complementary to photolithography, but not limited to planar patterning. It offers the capability of generating micro and nanostructures to a larger community than that familiar with conventional fabrication facilities. The first part of this thesis (chapter 1--4) focuses on the fabrication of microelectronic and micromagnetic devices. These successful demonstrations establish the compatibility of soft lithography with multilayer fabrication of functional devices, and open the door for the further development in these areas. Chapter 1 and 2 describe the use of microtransfer molding (muTM), micromolding in capillaries (MIMIC), and microcontact (muCP) for fabricating Schottky diodes and half-wave rectifier circuits. The fabrication processes involve multiple soft lithography steps and address the registrations between different layer of structures. Room temperature characteristics of these devices resemble those of diodes and rectifiers fabricated by photolithography. Chapter 3 and 4 demonstrate the fabrication of micromagnetic systems. In chapter 3, a one-dimensional bead motor is reported. Based on current-carrying wire systems, the bead motor can trap and transfer magnetic beads suspended in aqueous solutions. Chapter 4 shows a microfiltration system that uses arrays of nickel posts positioned in a polydimethylsiloxane (PDMS) microfluidic channel as the filtering elements. Turning on or off the magnetic field that is localized by these nickel posts can trap or release magnetic beads flowing by. The second part of this thesis (chapter 5--7) focuses on the development of unconventional microfabrication. The major objective underlying this work is to explore the simplest and most broadly available techniques that we could identify for forming patterns with features useful in functional microstructures. Chapter 5 and 6 describe the use of photographic films (microfiche and slide film) and transparencies printed using different printers as photomasks in the fabrication of PDMS stamps/molds for soft lithography. In chapter 6, we also compare different methods of generating microstructures using facilities readily and inexpensively available to chemistry and biology laboratories. Among the films and transparencies investigated, microfiche carries the highest resolution. It can generate structures as small as ˜10 mum in lateral dimensions. Chapter 7 shows a new rapid prototyping process for the fabrication of metallic microstructures using silver halide-based photographic film. The whole process, which involves photographic development and electrochemical deposition, only takes ˜2 hours, starting from a computer design file. It can generate electrically continuous structures with the smallest dimension of ˜30 mum in the plane of the film. The resulting structures---either supported on the film backing, or freed from it---are appropriate for use as passive, structural materials such as wire frames or meshes, and can also be used in microfluidic, microanalytical, and microelectromechanical systems (MEMS).

  11. Structure, chemistry, and stress corrosion cracking of grain boundaries in alloys 600 and 690

    NASA Astrophysics Data System (ADS)

    Stiller, Krystyna; Nilsson, Jan-Olof; Norring, Kjell

    1996-02-01

    The microstructure in six commercial batches of alloys 600 and 690 has been investigated using scanning electron microscopy (SEM), analytical transmission electron microscopy (ATEM), atom probe field ion microscopy (APFIM), and secondary ion mass spectroscopy (SIMS). The materials were also tested with respect to their resistance to intergranular stress corrosion cracking (IGSCC) in high-purity water at 365 °. Applied microanalytical techniques allowed direct measurement of carbon concentration in the matrix together with determination of grain boundary micro structure and microchemistry in all material conditions. The distribution of oxygen near a crack in material tested with respect to IGSCC was also investigated. The role of carbon and chromium and intergranular precipitates on IGSCC is discussed.

  12. Assessment of the geoavailability of trace elements from minerals in mine wastes: analytical techniques and assessment of selected copper minerals

    USGS Publications Warehouse

    Driscoll, Rhonda; Hageman, Phillip L.; Benzel, William M.; Diehl, Sharon F.; Adams, David T.; Morman, Suzette; Choate, LaDonna M.

    2012-01-01

    In this study, four randomly selected copper-bearing minerals were examined—azurite, malachite, bornite, and chalcopyrite. The objectives were to examine and enumerate the crystalline and chemical properties of each of the minerals, to determine which, if any, of the Cu-bearing minerals might adversely affect systems biota, and to provide a multi-procedure reference. Laboratory work included use of computational software for quantifying crystalline and amorphous material and optical and electron imaging instruments to model and project crystalline structures. Chemical weathering, human fluid, and enzyme simulation studies were also conducted. The analyses were conducted systematically: X-ray diffraction and microanalytical studies followed by a series of chemical, bio-leaching, and toxicity experiments.

  13. X-ray microanalytical surveys of minor element concentrations in unsectioned biological samples

    NASA Astrophysics Data System (ADS)

    Schofield, R. M. S.; Lefevre, H. W.; Overley, J. C.; Macdonald, J. D.

    1988-03-01

    Approximate concentration maps of small unsectioned biological samples are made using the pixel by pixel ratio of PIXE images to areal density images. Areal density images are derived from scanning transmission ion microscopy (STIM) proton energy-loss images. Corrections for X-ray production cross section variations, X-ray attenuation, and depth averaging are approximated or ignored. Estimates of the magnitude of the resulting error are made. Approximate calcium concentrations within the head of a fruit fly are reported. Concentrations in the retinula cell region of the eye average about 1 mg/g dry weight. Concentrations of zinc in the mandible of several ant species average about 40 mg/g. Zinc concentrations in the stomachs of these ants are at least 1 mg/g.

  14. Sample injector for high pressure liquid chromatography

    DOEpatents

    Paul, Phillip H.; Arnold, Don W.; Neyer, David W.

    2001-01-01

    Apparatus and method for driving a sample, having a well-defined volume, under pressure into a chromatography column. A conventional high pressure sampling valve is replaced by a sample injector composed of a pair of injector components connected in series to a common junction. The injector components are containers of porous dielectric material constructed so as to provide for electroosmotic flow of a sample into the junction. At an appropriate time, a pressure pulse from a high pressure source, that can be an electrokinetic pump, connected to the common junction, drives a portion of the sample, whose size is determined by the dead volume of the common junction, into the chromatographic column for subsequent separation and analysis. The apparatus can be fabricated on a substrate for microanalytical applications.

  15. A review of electrochemiluminescence (ECL) in and for microfluidic analytical devices.

    PubMed

    Kirschbaum, Stefanie E K; Baeumner, Antje J

    2015-05-01

    The concept and realization of microfluidic total analysis systems (microTAS) have revolutionized the analytical process by integrating the whole breadth of analytical techniques into miniaturized systems. Paramount for efficient and competitive microTAS are integrated detection strategies, which lead to low limits of detection while reducing the sample volume. The concept of electrochemiluminescence (ECL) has been intriguing ever since its introduction based on Ru(bpy)3 (2+) by Tokel and Bard [1] (J Am Chem Soc 1853:2862-2863, 1972), especially because of its immense sensitivity, nonexistent auto-luminescent background signal, and simplicity in experimental design. Therefore, integrating ECL detection into microTAS is a logical consequence to achieve simple, yet highly sensitive, sensors. However, published microanalytical devices employing ECL detection focus in general on traditional ECL chemistry and have yet to take advantage of advances made in standard bench-top ECL strategies. This review will therefore focus on the most recent advancements in microfluidic ECL approaches, but also evaluate the potential impact of bench-top ECL research progress that would further improve performance and lower limits of detection of micro analytical ECL systems, ensuring their desirability as detection principle for microTAS applications.

  16. Integrative molecular and microanalytical studies of syntrophic partnerships linking C, S, and N cycles in anoxic environments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orphan, Victoria

    2016-07-15

    Syntrophy and other forms of symbiotic associations between microorganisms are central to carbon and nutrient cycling in the environment. However, the inherent interdependence of these interactions, dynamic behavior, and frequent existence at thermodynamic limits has hindered our ability to both recognize syntrophic partnerships in nature and effectively study their behavior in the laboratory. To characterize and understand the underlying factors influencing syntrophic associations within complex communities requires a suite of tools that extend beyond basic molecular identification and cultivation. This specifically includes methods that preserve the natural spatial relationships between metabolically interdependent microorganisms while allowing downstream geochemical and/or molecular analysis.more » With support from this award, we have developed and applied new combinations of molecular, microscopy, and stable isotope-based methodologies that enable the characterization of fundamental links between phylogenetically-identified microorganisms and their specific metabolic activities and interactions in the environment. Through the coupling of fluorescence in situ hybridization (FISH) with cell capture and targeted metagenomics (Magneto-FISH), and FISH + secondary ion mass spectrometry (i.e. FISH-SIMS or FISH-nanoSIMS), we have defined new microbial interactions and the ecophysiology of anaerobic microorganisms involved in environmental methane cycling.« less

  17. Characterization and source term assessments of radioactive particles from Marshall Islands using non-destructive analytical techniques

    NASA Astrophysics Data System (ADS)

    Jernström, J.; Eriksson, M.; Simon, R.; Tamborini, G.; Bildstein, O.; Marquez, R. Carlos; Kehl, S. R.; Hamilton, T. F.; Ranebo, Y.; Betti, M.

    2006-08-01

    Six plutonium-containing particles stemming from Runit Island soil (Marshall Islands) were characterized by non-destructive analytical and microanalytical methods. Composition and elemental distribution in the particles were studied with synchrotron radiation based micro X-ray fluorescence spectrometry. Scanning electron microscope equipped with energy dispersive X-ray detector and with wavelength dispersive system as well as a secondary ion mass spectrometer were used to examine particle surfaces. Based on the elemental composition the particles were divided into two groups: particles with pure Pu matrix, and particles where the plutonium is included in Si/O-rich matrix being more heterogenously distributed. All of the particles were identified as nuclear fuel fragments of exploded weapon components. As containing plutonium with low 240Pu/ 239Pu atomic ratio, less than 0.065, which corresponds to weapons-grade plutonium or a detonation with low fission yield, the particles were identified to originate from the safety test and low-yield tests conducted in the history of Runit Island. The Si/O-rich particles contained traces of 137Cs ( 239 + 240 Pu/ 137Cs activity ratio higher than 2500), which indicated that a minor fission process occurred during the explosion. The average 241Am/ 239Pu atomic ratio in the six particles was 3.7 × 10 - 3 ± 0.2 × 10 - 3 (February 2006), which indicated that plutonium in the different particles had similar age.

  18. Aberration-Corrected STEM Imaging Through Off-Site Remote Operation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jarvis, Karalee; Allard Jr, Lawrence Frederick; Jerome, Timothy Y

    2010-01-01

    Recent advances in aberration-corrected electron microscopy have allowed researchers to image materials at sub- ngstr m resolution. Many of these modern instruments are designed to be operated from separate 'control' rooms, removing the effect of the operator on the instrument s physical environment. This capability also allows operation from suitable workstations, over internet connections, from literally anywhere in the world [1]. Researchers at the University of Texas at Austin (UTA) have collaborated with Oak Ridge National Laboratory (ORNL) and JEOL Ltd. to routinely conduct research sessions in which high-resolution images and X-ray microanalytical data are acquired during after-hours research sessions,more » utilizing the JEOL 2200FS aberration-corrected STEM/TEM at ORNL from their lab in Austin. Details of the remote operation are presented here.« less

  19. The evolution of Yellowstone's magmatic system over the past 630 kyr: Insights from the crystal record

    NASA Astrophysics Data System (ADS)

    Stelten, M. E.

    2017-12-01

    The Yellowstone Plateau volcanic field in northwestern Wyoming is one of the world's largest, active silicic volcanic centers, and has produced three caldera-forming "super eruptions" over the past 2.1 Myr. As a result, the petrologic evolution of Yellowstone's magmatic system has been the focus of numerous studies over the past 60 years. Early studies at Yellowstone focused on characterizing whole-rock chemical and isotopic variations observed in magmas erupted over Yellowstone's lifetime. While these have provided important insights into the source of Yellowstone magmas and the processes controlling their compositional evolution though time, whole-rock studies are limited in their ability to identify the mechanisms and timescales of rhyolite generation. In contrast, much of the recent work at Yellowstone has focused on applying micro-analytical techniques to characterize the age and composition of phenocrysts hosted in Yellowstone rhyolites. These studies have greatly advanced our understanding of the magmatic system at Yellowstone and have provided crucial new insights into the mechanisms and timescales of rhyolite generation. In particular, recent work has focused on applying micro-analytical techniques to study the age and origin of the [1] three caldera-forming eruptions that produced the Huckleberry Ridge, Mesa Falls, Lava Creek tuffs and [2] post-Lava Creek tuff intracaldera rhyolites that compose the Plateau Rhyolite. As a result, a wealth of crystal-chemical data now exists for rhyolites erupted throughout Yellowstone's 2.1 Myr history. These data provide a unique opportunity to create a detailed reconstruction of Yellowstone's magmatic system through time. In this contribution, I integrate available age, chemical, and isotopic data for phenocrysts hosted in Yellowstone rhyolites to construct a model for the evolution of Yellowstone's magmatic system from the caldera-forming eruption of the Lava Creek tuff at ca. 0.63 Ma to the present day. In particular, I highlight new insights into [1] the physical nature of Yellowstone's magmatic system, [2] the ways in which the mechanisms and timescales of rhyolite generation have changed though time, and [3] implications for the current state of the Yellowstone's magmatic system.

  20. Exploring clinical reasoning in novices: a self-regulated learning microanalytic assessment approach.

    PubMed

    Artino, Anthony R; Cleary, Timothy J; Dong, Ting; Hemmer, Paul A; Durning, Steven J

    2014-03-01

    The primary objectives of this study were to examine the regulatory processes of medical students as they completed a diagnostic reasoning task and to examine whether the strategic quality of these regulatory processes were related to short-term and longer-term medical education outcomes. A self-regulated learning (SRL) microanalytic assessment was administered to 71 second-year medical students while they read a clinical case and worked to formulate the most probable diagnosis. Verbal responses to open-ended questions targeting forethought and performance phase processes of a cyclical model of SRL were recorded verbatim and subsequently coded using a framework from prior research. Descriptive statistics and hierarchical linear regression models were used to examine the relationships between the SRL processes and several outcomes. Most participants (90%) reported focusing on specific diagnostic reasoning strategies during the task (metacognitive monitoring), but only about one-third of students referenced these strategies (e.g. identifying symptoms, integration) in relation to their task goals and plans for completing the task. After accounting for prior undergraduate achievement and verbal reasoning ability, strategic planning explained significant additional variance in course grade (ΔR(2 ) = 0.15, p < 0.01), second-year grade point average (ΔR(2) = 0.14, p < 0.01), United States Medical Licensing Examination Step 1 score (ΔR(2) = 0.08, p < 0.05) and National Board of Medical Examiner subject examination score in internal medicine (ΔR(2) = 0.10, p < 0.05). These findings suggest that most students in the formative stages of learning diagnostic reasoning skills are aware of and think about at least one key diagnostic reasoning process or strategy while solving a clinical case, but a substantially smaller percentage set goals or develop plans that incorporate such strategies. Given that students who developed more strategic plans achieved better outcomes, the potential importance of forethought regulatory processes is underscored. Published 2014. This article is a U.S. Government work and is in the public domain in the USA. Medical Education published by John Wiley & Sons Ltd.

  1. Ultrastructural and x-ray microanalytical observations of minocycline-related hyperpigmentation of the skin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sato, S.; Murphy, G.F.; Bernhard, J.D.

    1981-09-01

    In order to elucidate the nature and distribution of the pigment responsible for the circumscribed blue-black cutaneous hyperpigmentation occurring after administration of minocycline hydrochloride, transmission electron microscopy and energy-dispersive electron x-ray microanalysis were performed on lesional skin. Ultrastructural observations demonstrated electron-dense iron-containing particles either incorporated into a variety of siderosomes, within dermal histiocytes, free within the cytoplasm, or, rarely, scattered among dermal collagen fibers. Electron x-ray microanalysis confirmed iron content present within these particles. Although siderosomal inclusions contained occasional melanosome complexes, the degree of deposition of electron-dense iron-containing particles in dermal histiocytes seemed to be primarily responsible for the blue-blackmore » discoloration of the skin. The present study is an investigation of the structure and composition of the pigment responsible for minocycline-related cutaneous hyperpigmentation.« less

  2. Electrochemical Sensors for the Detection of Lead and Other Toxic Heavy Metals: The Next Generation of Personal Exposure Biomonitors

    PubMed Central

    Yantasee, Wassana; Lin, Yuehe; Hongsirikarn, Kitiya; Fryxell, Glen E.; Addleman, Raymond; Timchalk, Charles

    2007-01-01

    To support the development and implementation of biological monitoring programs, we need quantitative technologies for measuring xenobiotic exposure. Microanalytical based sensors that work with complex biomatrices such as blood, urine, or saliva are being developed and validated and will improve our ability to make definitive associations between chemical exposures and disease. Among toxic metals, lead continues to be one of the most problematic. Despite considerable efforts to identify and eliminate Pb exposure sources, this metal remains a significant health concern, particularly for young children. Ongoing research focuses on the development of portable metal analyzers that have many advantages over current available technologies, thus potentially representing the next generation of toxic metal analyzers. In this article, we highlight the development and validation of two classes of metal analyzers for the voltammetric detection of Pb, including: a) an analyzer based on flow injection analysis and anodic stripping voltammetry at a mercury-film electrode, and b) Hg-free metal analyzers employing adsorptive stripping voltammetry and novel nanostructure materials that include the self-assembled monolayers on mesoporous supports and carbon nanotubes. These sensors have been optimized to detect Pb in urine, blood, and saliva as accurately as the state-of-the-art inductively coupled plasma-mass spectrometry with high reproducibility, and sensitivity allows. These improved and portable analytical sensor platforms will facilitate our ability to conduct biological monitoring programs to understand the relationship between chemical exposure assessment and disease outcomes. PMID:18087583

  3. Pedothem carbonates reveal anomalous North American atmospheric circulation 70,000–55,000 years ago

    PubMed Central

    Sharp, Warren D.; Oster, Jessica L.; Ebeling, Angela; Valley, John W.; Kozdon, Reinhard; Orland, Ian J.; Woodhead, Jon D.; Hergt, Janet M.; Chadwick, Oliver A.; Amundson, Ronald

    2016-01-01

    Our understanding of climatic conditions, and therefore forcing factors, in North America during the past two glacial cycles is limited in part by the scarcity of long, well-dated, continuous paleoclimate records. Here, we present the first, to our knowledge, continuous, millennial-resolution paleoclimate proxy record derived from millimeter-thick pedogenic carbonate clast coatings (pedothems), which are widely distributed in semiarid to arid regions worldwide. Our new multiisotope pedothem record from the Wind River Basin in Wyoming confirms a previously hypothesized period of increased transport of Gulf of Mexico moisture northward into the continental interior from 70,000 to 55,000 years ago based on oxygen and carbon isotopes determined by ion microprobe and uranium isotopes and U-Th dating by laser ablation inductively coupled plasma mass spectrometry. This pronounced meridional moisture transport, which contrasts with the dominant zonal transport of Pacific moisture into the North American interior by westerly winds before and after 70,000–55,000 years ago, may have resulted from a persistent anticyclone developed above the North American ice sheet during Marine Isotope Stage 4. We conclude that pedothems, when analyzed using microanalytical techniques, can provide high-resolution paleoclimate records that may open new avenues into understanding past terrestrial climates in regions where paleoclimate records are not otherwise available. When pedothem paleoclimate records are combined with existing records they will add complimentary soil-based perspectives on paleoclimate conditions. PMID:26755592

  4. Analysis of defect structure in silicon. Characterization of SEMIX material. Silicon sheet growth development for the large area silicon sheet task of the low-cost solar array project

    NASA Technical Reports Server (NTRS)

    Natesh, R.; Stringfellow, G. B.; Virkar, A. V.; Dunn, J.; Guyer, T.

    1983-01-01

    Statistically significant quantitative structural imperfection measurements were made on samples from ubiquitous crystalline process (UCP) Ingot 5848 - 13C. Important correlation was obtained between defect densities, cell efficiency, and diffusion length. Grain boundary substructure displayed a strong influence on the conversion efficiency of solar cells from Semix material. Quantitative microscopy measurements gave statistically significant information compared to other microanalytical techniques. A surface preparation technique to obtain proper contrast of structural defects suitable for quantimet quantitative image analyzer (QTM) analysis was perfected and is used routinely. The relationships between hole mobility and grain boundary density was determined. Mobility was measured using the van der Pauw technique, and grain boundary density was measured using quantitative microscopy technique. Mobility was found to decrease with increasing grain boundary density.

  5. Tortuous path chemical preconcentrator

    DOEpatents

    Manginell, Ronald P.; Lewis, Patrick R.; Adkins, Douglas R.; Wheeler, David R.; Simonson, Robert J.

    2010-09-21

    A non-planar, tortuous path chemical preconcentrator has a high internal surface area having a heatable sorptive coating that can be used to selectively collect and concentrate one or more chemical species of interest from a fluid stream that can be rapidly released as a concentrated plug into an analytical or microanalytical chain for separation and detection. The non-planar chemical preconcentrator comprises a sorptive support structure having a tortuous flow path. The tortuosity provides repeated twists, turns, and bends to the flow, thereby increasing the interfacial contact between sample fluid stream and the sorptive material. The tortuous path also provides more opportunities for desorption and readsorption of volatile species. Further, the thermal efficiency of the tortuous path chemical preconcentrator is comparable or superior to the prior non-planar chemical preconcentrator. Finally, the tortuosity can be varied in different directions to optimize flow rates during the adsorption and desorption phases of operation of the preconcentrator.

  6. Preparation of metallic Pd nanoparticles using supercritical CO2 deposition: An efficient catalyst for Suzuki cross-coupling reaction

    NASA Astrophysics Data System (ADS)

    Tezcan, Burcu; Ulusal, Fatma; Egitmen, Asım; Guzel, Bilgehan

    2018-05-01

    Ligand-free palladium nanoparticles supported on multi-walled carbon nanotubes (Pd/MWCNT) were prepared by the supercritical carbon dioxide (scCO2) deposition method using a novel scCO2-soluble Pd organometallic complex as a precursor. The precursor with the perfluoroalkyl chain group was synthesized and identified by microanalytic methods. The deposition was carried out at the temperature of 363.15 K and pressure of 27.6 MPa CO2. The prepared metallic nanoparticles were obtained with an average size of 2 nm. Pd/MWCNT was utilized as a heterogeneous catalyst in Suzuki cross-coupling reaction. The nanocatalyst was found very effective in Suzuki reaction and it could also be recovered easily from the reaction media and reused over several cycles without significant loss of catalytic activity under mild conditions. [Figure not available: see fulltext.

  7. Synthesis, in Vivo Anti-inflammatory, and in Vitro Antimicrobial Activity of New 5-Benzofuranyl Fused Pyrimidines.

    PubMed

    Nassar, Ekhlass; El-Badry, Yaser Abdel-Moemen; El Kazaz, Hagar

    2016-01-01

    Chalcone (3) has been synthesized as a new chalcone derivative bearing benzofuran moiety at 1 position. Such chalcone was used as a model dielectrophile applied to react with some nucleophiles such as 5-amino pyrazoles, 5-amino-1,2,4-triazole, 2-aminobenzimidazole, and 6-uraciles under Michael reaction conditions and resulted in a new series of fused pyrimidines such as pyrazolo[1,5-a]pyrimidines 7a-e, [1,2,4]-triazolo[1,5-a]pyrimidine 9, pyrimido[1,2-a]benzimidazole 11, and synthesis of pyrido[2,3-d]pyrimidinones 13a and b. The structures of the synthesized target heterocyclic compounds were confirmed by microanalytical and spectral data such as Fourier transform (FT)-IR, (1)H-NMR, and MS spectra. The newly synthesized compounds were evaluated for their anti-inflammatory and antimicrobial activities; most showed significant activities.

  8. Effects of lead pollution on Ammonia parkinsoniana (foraminifera): ultrastructural and microanalytical approaches.

    PubMed

    Frontalini, F; Curzi, D; Giordano, F M; Bernhard, J M; Falcieri, E; Coccioni, R

    2015-01-30

    The responses of Ammonia parkinsoniana (Foraminifera) exposed to different concentrations of lead (Pb) were evaluated at the cytological level. Foraminifera-bearing sediments were placed in mesocosms that were housed in aquaria each with seawater of a different lead concentration. On the basis of transmission electron microscopy and environmental scanning electron microscopy coupled with energy dispersive spectrometer analyses, it was possible to recognize numerous morphological differences between untreated (i.e., control) and treated (i.e., lead enrichment) specimens. In particular, higher concentrations of this pollutant led to numerical increase of lipid droplets characterized by a more electron-dense core, proliferation of residual bodies, a thickening of the organic lining, mitochondrial degeneration, autophagosome proliferation and the development of inorganic aggregates.  All these cytological modifications might be related to the pollutant-induced stress and some of them such as the thickening of organic lining might suggest a potential mechanism of protection adopted by foraminifera.

  9. Synthesis and characterization of ligational behavior of curcumin drug towards some transition metal ions: Chelation effect on their thermal stability and biological activity

    NASA Astrophysics Data System (ADS)

    Refat, Moamen S.

    2013-03-01

    Complexes of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with curcumin ligand as antitumor activity were synthesized and characterized by elemental analysis, conductometry, magnetic susceptibility, UV-Vis, IR, Raman, ESR, 1H-NMR spectroscopy, X-ray diffraction analysis of powdered samples and thermal analysis, and screened for antimicrobial activity. The IR spectral data suggested that the ligand behaves as a monobasic bidentate ligand towards the central metal ion with an oxygen's donor atoms sequence of both sbnd OH and Cdbnd O groups under keto-enol structure. From the microanalytical data, the stoichiometry of the complexes 1:2 (metal:ligand) was found. The ligand and their metal complexes were screened for antibacterial activity against Escherichia Coli, Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa and fungicidal activity against Aspergillus flavus and Candida albicans.

  10. Miniature Bioreactor System for Long-Term Cell Culture

    NASA Technical Reports Server (NTRS)

    Gonda, Steve R.; Kleis, Stanley J.; Geffert, Sandara K.

    2010-01-01

    A prototype miniature bioreactor system is designed to serve as a laboratory benchtop cell-culturing system that minimizes the need for relatively expensive equipment and reagents and can be operated under computer control, thereby reducing the time and effort required of human investigators and reducing uncertainty in results. The system includes a bioreactor, a fluid-handling subsystem, a chamber wherein the bioreactor is maintained in a controlled atmosphere at a controlled temperature, and associated control subsystems. The system can be used to culture both anchorage-dependent and suspension cells, which can be either prokaryotic or eukaryotic. Cells can be cultured for extended periods of time in this system, and samples of cells can be extracted and analyzed at specified intervals. By integrating this system with one or more microanalytical instrument(s), one can construct a complete automated analytical system that can be tailored to perform one or more of a large variety of assays.

  11. Immunoaffinity chromatography: an introduction to applications and recent developments

    PubMed Central

    Moser, Annette C

    2010-01-01

    Immunoaffinity chromatography (IAC) combines the use of LC with the specific binding of antibodies or related agents. The resulting method can be used in assays for a particular target or for purification and concentration of analytes prior to further examination by another technique. This review discusses the history and principles of IAC and the various formats that can be used with this method. An overview is given of the general properties of antibodies and of antibody-production methods. The supports and immobilization methods used with antibodies in IAC and the selection of application and elution conditions for IAC are also discussed. Several applications of IAC are considered, including its use in purification, immunodepletion, direct sample analysis, chromatographic immunoassays and combined analysis methods. Recent developments include the use of IAC with CE or MS, ultrafast immunoextraction methods and the use of immunoaffinity columns in microanalytical systems. PMID:20640220

  12. Characterization of blue decorated Renaissance pottery fragments from Caltagirone (Sicily, Italy)

    NASA Astrophysics Data System (ADS)

    Barilaro, D.; Crupi, V.; Interdonato, S.; Majolino, D.; Venuti, V.; Barone, G.; La Russa, M. F.; Bardelli, F.

    2008-07-01

    Renaissance blue decorated pottery fragments from the archaeological site of Caltagirone (Sicily, Italy) were analysed by scanning electron microscopy - energy dispersive X-ray spectrometry (SEM/EDS). The samples were dated back to 16th century AD on the basis of archaeological observations. The micro-chemical analyses were performed on the ceramic body and the surface decorated layer of the samples. Particularly, the investigation was addressed the characterization of the coating blue decorations. The obtained results allowed us to clearly identify smalt as pigment. Also the presence of arsenic (As) was revealed and the Co/As ratio values were calculated and related to the different process used for the pigment preparation. Further spectroscopic analyses, performed through X-ray absorbance spectroscopy (XAS), carried out at the Co K-edge, confirmed the micro-analytical results and permitted us to identify the oxidation form and the local environment of cobalt atoms.

  13. Microdisc gel electrophoresis in sodium dodecyl sulfate of organic material from rat otoconial complexes

    NASA Technical Reports Server (NTRS)

    Ross, M. D.; Pote, K. G.; Rarey, K. E.; Verma, L. M.

    1981-01-01

    The gravity receptors of all vertebrates utilize a 'test mass' consisting of a complex arrangement of mineral and organic substance that lies over the sensory receptor areas. In most vertebrates, the mineral is a polymorph of calcium carbonate in the form of minute, single crystals called otoconia. An investigation is conducted to determine the number of proteins in otoconial complexes and their molecular weights. The investigation makes use of a microdisk gel electrophoresis method reported by Gainer (1971). The most important finding of the reported research is that analysis of the proteins of the organic material of the otoconial complexes is possible when sensitive microanalytical methods are employed. Further modification of the basic technique employed and the inclusion of other sensitive staining methods should mean that, in the future, protein separation by molecular weight will be possible in sample pools containing only two otoconial masses.

  14. Progress Towards an Open Data Ecosystem for Australian Geochemistry and Geochronology Data

    NASA Astrophysics Data System (ADS)

    McInnes, B.; Rawling, T.; Brown, W.; Liffers, M.; Wyborn, L. A.; Brown, A.; Cox, S. J. D.

    2016-12-01

    Technological improvements in laboratory automation and microanalytical methods are producing an unprecedented volume of high-value geochemical data for use by geoscientists in understanding geological and planetary processes. In contrast, the research infrastructure necessary to systematically manage, deliver and archive analytical data has not progressed much beyond the minimum effort necessary to produce a peer-reviewed publication. Anecdotal evidence indicates that the majority of publically funded data is underreported, and what is published is relatively undiscoverable to experienced researchers let alone the general public. Government-funded "open data" initiatives have a role to play in the development of networks of data management and delivery ecosystems and practices allowing access to publically funded data. This paper reports on progress in Australia towards creation of an open data ecosystem involving multiple academic and government research institutions cooperating to create an open data architecture linking researchers, physical samples, sample metadata, laboratory metadata, analytical data and consumers.

  15. Polymer-encapsulated metal nanoparticles: optical, structural, micro-analytical and hydrogenation studies of a composite material.

    PubMed

    Scalzullo, Stefania; Mondal, Kartick; Witcomb, Mike; Deshmukh, Amit; Scurrell, Mike; Mallick, Kaushik

    2008-02-20

    A single-step synthesis route is described for the preparation of a metal-polymer composite in which palladium acetate and meta-amino benzoic acid were used as the precursors for palladium nanoparticles and poly(meta-amino benzoic acid) (PABA). The palladium nanoparticles were found to be uniformly dispersed and highly stabilized throughout the macromolecule matrix. The resultant composite material was characterized by means of different techniques, such as IR and Raman spectroscopy, which provided information regarding the chemical structure of the polymer, whereas electron microscopy images yielded information regarding the morphology of the composite material and the distribution of the metal particles in the composite material. The composite material was used as a catalyst for the ethylene hydrogenation reaction and showed catalytic activity at higher temperatures. TEM studies confirmed the changed environment of the nanoparticles at these temperatures.

  16. Microscopy and Microanalysis of Blood in a Snake Head Fish, Channa gachua Exposed to Environmental Pollution.

    PubMed

    Pala, Eva M; Dey, Sudip

    2016-02-01

    Conventional and highly sophisticated analytical methods (Cyria et al., 1989; Massar et al., 2012a) were used to analyze micro-structural and micro-analytical aspects of the blood of snake head fish, Channa gachua, exposed to municipal wastes and city garbage. Red (RBC) and white blood cell (WBC) counts and hemhemoglobin content were found to be higher in pollution affected fish as compared with control. Scanning electron microscopy revealed the occurrence of abnormal erythrocytes such as crenated cells, echinocytes, lobopodial projections, membrane internalization, spherocytes, ruptured cells, contracted cells, depression, and uneven elongation of erythrocyte membranes in fish inhabiting the polluted sites. Energy-dispersive X-ray spectroscopy (EDS) revealed the presence of silicon and lead in the RBCs of pollution affected fish. Significance of the study includes the highly sophisticated analytical approach, which revealed the aforementioned micro-structural abnormalities.

  17. Constraints on the timing of multiple thermal events and re-equilibration recorded by high-U zircon and xenotime: Case study of pegmatite from Piława Górna (Góry Sowie Block, SW Poland)

    NASA Astrophysics Data System (ADS)

    Budzyń, Bartosz; Sláma, Jiří; Kozub-Budzyń, Gabriela A.; Konečný, Patrik; Holický, Ivan; Rzepa, Grzegorz; Jastrzębski, Mirosław

    2018-06-01

    The application of zircon and xenotime geochronometers requires knowledge of their potential and limitations related to possible disturbance of the age record. The alteration of the intergrown zircon and xenotime in pegmatite from the Góry Sowie Block (SW Poland) was studied using the electron microprobe analysis, X-ray WDS compositional mapping, micro-Raman analysis, and LA-ICP-MS U-Pb dating of zircon and xenotime, as well as the U-Th-total Pb dating of uraninite. These microanalytical techniques were applied to understand the formation mechanisms of the secondary textures related to post-magmatic processes in the zircon and xenotime intergrowth, and to constrain their timing. Textural and compositional features combined with U-Pb data indicate that the pegmatite-related crystallization of the zircon and xenotime intergrowth occurred ca. 2.09 Ga (2086 ± 35 Ma for zircon and 2093 ± 52 Ma for xenotime), followed by the re-equilibration of zircon and xenotime ca. 370 Ma (373 ± 18 Ma and 368 ± 6 Ma, respectively) during the formation of the younger pegmatite. The zircon and xenotime were most likely derived from Precambrian basement rocks and emplaced in the pegmatite as a restite. The zircon preserved textures related to diffusion-reaction processes that affected its high-U core (up to ca. 9.6 wt% UO2), which underwent further metamictization and amorphization due to self-radiation damage. The zircon rim and xenotime were affected by coupled dissolution-reprecipitation processes that resulted in patchy zoning, age disturbance and sponge-like textures. Xenotime was also partially replaced by fluorapatite or hingganite-(Y) and Y-enriched allanite-(Ce). The termination of the low-temperature alteration was constrained by the U-Th-total Pb age of the uraninite inclusions that crystallized in zircon at 281 ± 2 Ma, which is consistent with the age of 278 ± 15 Ma obtained from the youngest cluster of U-Pb ages in the re-equilibrated high-U zircon domains. This study demonstrates the importance of the careful examination of compositional, microtextural and geochronological data obtained using microanalytical techniques to reconstruct the complex thermal histories recorded by accessory minerals.

  18. Detecting Cancer Quickly and Accurately

    NASA Astrophysics Data System (ADS)

    Gourley, Paul; McDonald, Anthony; Hendricks, Judy; Copeland, Guild; Hunter, John; Akhil, Ohmar; Capps, Heather; Curry, Marc; Skirboll, Steve

    2000-03-01

    We present a new technique for high throughput screening of tumor cells in a sensitive nanodevice that has the potential to quickly identify a cell population that has begun the rapid protein synthesis and mitosis characteristic of cancer cell proliferation. Currently, pathologists rely on microscopic examination of cell morphology using century-old staining methods that are labor-intensive, time-consuming and frequently in error. New micro-analytical methods for automated, real time screening without chemical modification are critically needed to advance pathology and improve diagnoses. We have teamed scientists with physicians to create a microlaser biochip (based upon our R&D award winning bio-laser concept)1 which evaluates tumor cells by quantifying their growth kinetics. The key new discovery was demonstrating that the lasing spectra are sensitive to the biomolecular mass in the cell, which changes the speed of light in the laser microcavity. Initial results with normal and cancerous human brain cells show that only a few hundred cells -- the equivalent of a billionth of a liter -- are required to detect abnormal growth. The ability to detect cancer in such a minute tissue sample is crucial for resecting a tumor margin or grading highly localized tumor malignancy. 1. P. L. Gourley, NanoLasers, Scientific American, March 1998, pp. 56-61. This work supported under DOE contract DE-AC04-94AL85000 and the Office of Basic Energy Sciences.

  19. Design and fabrication of a multilayered polymer microfluidic chip with nanofluidic interconnects via adhesive contact printing.

    PubMed

    Flachsbart, Bruce R; Wong, Kachuen; Iannacone, Jamie M; Abante, Edward N; Vlach, Robert L; Rauchfuss, Peter A; Bohn, Paul W; Sweedler, Jonathan V; Shannon, Mark A

    2006-05-01

    The design and fabrication of a multilayered polymer micro-nanofluidic chip is described that consists of poly(methylmethacrylate) (PMMA) layers that contain microfluidic channels separated in the vertical direction by polycarbonate (PC) membranes that incorporate an array of nanometre diameter cylindrical pores. The materials are optically transparent to allow inspection of the fluids within the channels in the near UV and visible spectrum. The design architecture enables nanofluidic interconnections to be placed in the vertical direction between microfluidic channels. Such an architecture allows microchannel separations within the chip, as well as allowing unique operations that utilize nanocapillary interconnects: the separation of analytes based on molecular size, channel isolation, enhanced mixing, and sample concentration. Device fabrication is made possible by a transfer process of labile membranes and the development of a contact printing method for a thermally curable epoxy based adhesive. This adhesive is shown to have bond strengths that prevent leakage and delamination and channel rupture tests exceed 6 atm (0.6 MPa) under applied pressure. Channels 100 microm in width and 20 microm in depth are contact printed without the adhesive entering the microchannel. The chip is characterized in terms of resistivity measurements along the microfluidic channels, electroosmotic flow (EOF) measurements at different pH values and laser-induced-fluorescence (LIF) detection of green-fluorescent protein (GFP) plugs injected across the nanocapillary membrane and into a microfluidic channel. The results indicate that the mixed polymer micro-nanofluidic multilayer chip has electrical characteristics needed for use in microanalytical systems.

  20. Orbital transfer vehicle launch operations study: Manpower summary and facility requirements, volume 5

    NASA Technical Reports Server (NTRS)

    1986-01-01

    All manpower numbers, number of heads (by skill), serial time and manhours have been accumulated and compiled on a per subtask basis in spreadsheet format for both the ground based and the space based data flows. To aid in identifying the facility resources required to process the Ground Based Orbital Transfer Vehicle (GBOTV) and/or the space based orbital transfer vehicle (SBOTV) through the ground facilities at Kennedy Space Center (KSC), a software application package was developed using a general purpose data base management system known as Data Flex. The facility requirements are used as the basic input to this software application. The resources of the KSC facility that could be used by orbital transfer vehicle program were digitized in the same format used to identify facility requirements. The facility capabilities were digitized in this format for subsequent, automated comparative analyses. Composite facility requirements are compared to each of the baseline facility capabilities and the system generates a relative score that indicates how each facility weighs against the composite requirements in relation to the other facilities in the set.

  1. Ion beam analyses of radionuclide migration in heterogeneous rocks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alonso, Ursula; Missana, Tiziana; Garcia-Gutierrez, Miguel

    2013-07-18

    The migration of radionuclides (RN) in the environment is a topic of general interest, for its implications on public health, and it is an issue for the long-term safety studies of deep geological repositories (DGR) for high-level radioactive waste. The role played by colloids on RN migration is also of great concern. Diffusion and sorption are fundamental mechanisms controlling RN migration in rocks and many experimental approaches are applied to determine transport parameters for low sorbing RN in homogeneous rocks. However, it is difficult to obtain relevant data for high sorbing RN or colloids, for which diffusion lengths are extremelymore » short, or within heterogeneous rocks, where transport might be different in different minerals. The ion beam techniques Rutherford Backscattering Spectrometry (RBS) and micro-Particle Induced X-Ray Emission ({mu}PIXE), rarely applied in the field, were selected for their micro-analytical potential to study RN diffusion and surface retention within heterogeneous rocks. Main achievements obtained during last 12 years are highlighted.« less

  2. Compartmentation of metals in foliage of Populus tremula grown on soils with mixed contamination. II. Zinc binding inside leaf cell organelles.

    PubMed

    Vollenweider, Pierre; Bernasconi, Petra; Gautschi, Hans-Peter; Menard, Terry; Frey, Beat; Günthardt-Goerg, Madeleine S

    2011-01-01

    The phytoextraction potential of plants for removing heavy metals from polluted soils is determined by their capacity to store contaminants in aboveground organs and complex them safely. In this study, the metal compartmentation, elemental composition of zinc deposits and zinc complexation within leaves from poplars grown on soil with mixed metal contamination was analysed combining several histochemical and microanalytical approaches. Zinc was the only heavy metal detected and was stored in several organelles in the form of globoid deposits showing β-metachromasy. It was associated to oxygen anions and different cations, noteworthy phosphorous. The deposit structure, elemental composition and element ratios indicated that zinc was chelated by phytic acid ligands. Maturation processes in vacuolar vs. cytoplasmic deposits were suggested by differences in size and amounts of complexed zinc. Hence, zinc complexation by phytate contributed to metal detoxification and accumulation in foliage but could not prevent toxicity reactions therein. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Cytology of pollutant metals in marine invertebrates: A review of microanalytical applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nott, J.A.

    1991-03-01

    x-ray microanalysis (XRMA) is customized for investigations of the metabolic and detoxification strategies of heavy metals taken by marine organisms from polluted environments. Sites of uptake, intracellular accumulation, transport and excretion are visualized, analysed and quantified. Cryopreparation techniques are required to prevent the translocation or loss from specimens of soluble metal species. In marine invertebrates, metals are detoxified by systems of chemical binding and intracellular compartmentalization. XRMA investigations have concentrated on marine molluscs and crustaceans and even within these restricted groups there are marked inter-species differences in the biochemical and cytological processes which reduce metal bioavailability. Some detoxification systems alsomore » protect the carnivores which ingest the metal-laden tissues of the prey. This results in the bioreduction of metals along a food chain. These processes are investigated by XRMA which can be tuned to observe the complex interactions which operate at all levels within and between the biota and polluted environments. 90 refs.« less

  4. Mechanical stability of heat-treated nanoporous anodic alumina subjected to repetitive mechanical deformation

    NASA Astrophysics Data System (ADS)

    Bankova, A.; Videkov, V.; Tzaneva, B.; Mitov, M.

    2018-03-01

    We report studies on the mechanical response and deformation behavior of heat-treated nanoporous anodic alumina using a micro-balance test and experimental test equipment especially designed for this purpose. AAO samples were characterized mechanically by a three-point bending test using a micro-analytical balance. The deformation behavior was studied by repetitive mechanical bending of the AAO membranes using an electronically controlled system. The nanoporous AAO structures were prepared electrochemically from Al sheet substrates using a two-step anodizing technique in oxalic acid followed by heat treatment at 700 °C in air. The morphological study of the aluminum oxide layer after the mechanical tests and mechanical deformation was conducted using scanning electron and optical microscopy, respectively. The experimental results showed that the techniques proposed are simple and accurate; they could, therefore, be combined to constitute a method for mechanical stability assessment of nanostructured AAO films, which are important structural components in the design of MEMS devices and sensors.

  5. Integrated Experimental and Modelling Research for Non-Ferrous Smelting and Recycling Systems

    NASA Astrophysics Data System (ADS)

    Jak, Evgueni; Hidayat, Taufiq; Shishin, Denis; Mehrjardi, Ata Fallah; Chen, Jiang; Decterov, Sergei; Hayes, Peter

    The chemistries of industrial pyrometallurgical non-ferrous smelting and recycling processes are becoming increasingly complex. Optimisation of process conditions, charge composition, temperature, oxygen partial pressure, and partitioning of minor elements between phases and different process streams require accurate description of phase equilibria and thermodynamics which are the focus of the present research. The experiments involve high temperature equilibration in controlled gas atmospheres, rapid quenching and direct measurement of equilibrium phase compositions with quantitative microanalytical techniques including electron probe X-ray microanalysis and Laser Ablation ICP-MS. The thermodynamic modelling is undertaken using computer package FactSage with the quasi-chemical model for the liquid slag phase and other advanced models. Experimental and modelling studies are combined into an integrated research program focused on the major elements Cu-Pb-Fe-O-Si-S system, slagging Al, Ca, Mg and other minor elements. The ongoing development of the research methodologies has resulted in significant advances in research capabilities. Examples of applications are given.

  6. Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor.

    PubMed

    Makos, Monique A; Omiatek, Donna M; Ewing, Andrew G; Heien, Michael L

    2010-06-15

    This work describes the development and characterization of a modified carbon-fiber microelectrode sensor capable of measuring real-time physiological pH changes in biological microenvironments. The reagentless sensor was fabricated under ambient conditions from voltammetric reduction of the diazonium salt Fast Blue RR onto a carbon-fiber surface in aprotic media. Fast-scan cyclic voltammetry was used to probe redox activity of the p-quinone moiety of the surface-bound molecule as a function of pH. In vitro calibration of the sensor in solutions ranging from pH 6.5 to 8.0 resulted in a pH-dependent anodic peak potential response. Flow-injection analysis was used to characterize the modified microelectrode, revealing sensitivity to acidic and basic changes discernible to 0.005 pH units. Furthermore, the modified electrode was used to measure dynamic in vivo pH changes evoked during neurotransmitter release in the central nervous system of the microanalytical model organism Drosophila melanogaster.

  7. Aging effect on Zn retention on a calcareous soil: column experiments and synchrotron X-ray micro-spectroscopic investigation.

    PubMed

    Sayen, Stéphanie; Guillon, Emmanuel

    2014-07-15

    In this study, a combination of column experiments and micro-analytical techniques exploiting synchrotron generated X-rays was used to assess the effect of aging time on Zn retention and mobility in the specific case of calcareous soils (high pH value, ≈ 8). The samples were subjected to aging for 2, 6, 17, and 63 days. Freshly added Zn mainly existed as an exchangeable form, and this metal fraction decreased over time due to Zn redistribution to stronger binding sites. Thus, after aging for 63 days, 45% of Zn is remobilized from exchangeable sites to stronger binding sites. μ-XRF maps were used to find correlations among elements in the sample, and μ-XANES spectra were recorded to precise Zn speciation. These analyses evidenced an increasing partitioning of Zn from organic matter to iron oxy(hydr)oxides over time. The occurrence of hydrozincite is evidenced in all samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Characterization of uranium tetrafluoride (UF 4) with Raman spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Villa-Aleman, Eliel; Wellons, Matthew S.

    The Raman spectrum of uranium tetrafluoride (UF 4) is unambiguously characterized with multiple Raman excitation laser sources for the first time. Across different laser excitation wavelengths, UF 4 demonstrates 16 distinct Raman bands within the 50-400 cm -1 region. The observed Raman bands are representative of various F-F vibrational modes. UF 4 also shows intense fluorescent bands in the 325 – 750 nm spectral region. Comparison of the UF 4 spectrum with the ZrF 4 spectrum, its crystalline analog, demonstrates a similar Raman band structure consistent with group theory predictions for expected Raman bands. Additionally, a demonstration of combined scanningmore » electron microscopy (SEM) and in situ Raman spectroscopy microanalytical measurements of UF 4 particulates shows that despite the inherent weak intensity of Raman bands, identification and characterization are possible for micron-sized particulates with modern instrumentation. The published well characterized UF 4 spectrum is extremely relevant to nuclear materials and nuclear safeguard applications.« less

  9. Characterization of uranium tetrafluoride (UF 4) with Raman spectroscopy

    DOE PAGES

    Villa-Aleman, Eliel; Wellons, Matthew S.

    2016-03-22

    The Raman spectrum of uranium tetrafluoride (UF 4) is unambiguously characterized with multiple Raman excitation laser sources for the first time. Across different laser excitation wavelengths, UF 4 demonstrates 16 distinct Raman bands within the 50-400 cm -1 region. The observed Raman bands are representative of various F-F vibrational modes. UF 4 also shows intense fluorescent bands in the 325 – 750 nm spectral region. Comparison of the UF 4 spectrum with the ZrF 4 spectrum, its crystalline analog, demonstrates a similar Raman band structure consistent with group theory predictions for expected Raman bands. Additionally, a demonstration of combined scanningmore » electron microscopy (SEM) and in situ Raman spectroscopy microanalytical measurements of UF 4 particulates shows that despite the inherent weak intensity of Raman bands, identification and characterization are possible for micron-sized particulates with modern instrumentation. The published well characterized UF 4 spectrum is extremely relevant to nuclear materials and nuclear safeguard applications.« less

  10. Wear of liquid nitrogen-cooled 440C bearing steels in an oxygen environment

    NASA Technical Reports Server (NTRS)

    Chaudhuri, Dilip K.; Verma, Ravi

    1988-01-01

    This paper presents up-to-date findings of the research being conducted to understand the mechanism of sliding wear in unlubricated 440C bearing steels under oxidative conditions. A sliding wear test rig has been designed and built with a cylinder-on-flat geometry. The equipment is capable of testing specimens under high axial loads and sliding speeds in a simulated LOX environment. Samples of 440C steel, quenched and tempered to a hardness of Rc 56, were tested under a load of 890 N and a sliding speed of 2.05 m/sec for total sliding distances of up to 5.54 km. Flash temperatures during these tests were measured with an IR camera and a fast digital recorder. Microstructural and microanalytical data from the worn surfaces and the debris particles are analyzed extensively, along with wear rates, flash temperatures, surface profiles, hardnesses, and residual stresses, in the context of oxidation and wear theories.

  11. The development of maternal touch across the first year of life.

    PubMed

    Ferber, Sari Goldstein; Feldman, Ruth; Makhoul, Imad R

    2008-06-01

    The developmental trajectories of specific forms of maternal touch during natural caregiving were examined across the first year in relation to the development of mother-infant reciprocal communication. One hundred and thirty-one mothers and infants in four groups aged 3, 6, 9, and 12 months were observed in a cross-sectional design at home during natural caregiving and mother-child play sessions. Microanalytic coding of the caregiving sessions considered nine forms of maternal touch, which were aggregated into three global touch categories: affectionate, stimulating, and instrumental. Play sessions were coded for maternal sensitivity and dyadic reciprocity. Maternal affectionate and stimulating touch decreased significantly during the second 6 months of life. In parallel, dyadic reciprocity increased in the second half year. Dyadic reciprocity was predicted by the frequency of affectionate touch but not by any other form of touch. Results contribute to specifying the role of touch as it evolves across the first year of life within the global mother-infant communication system.

  12. [Microanalytical identification of barium sulphate crystals in statoliths of Chara rhizoids (Ch. fragilis, desv.)].

    PubMed

    Schröter, K; Läuchli, A; Sievers, A

    1975-01-01

    In contrast to the statocytes of higher plants, in which amyloplasts function as statoliths, Chara-rhizoids contain statolith vacuoles filled with biocrystallites of BaSO4. This was revealed by qualitative and quantitative electron microprobe analysis, atomic absorption spectrophotometry and selected area electron diffraction. The barium sulphate crystallites are rods which are linearly composed of globular subunits approximately 7 nm in diameter.The electron optical evidence of the crystallites depends on the nature of the fixatives. Best structural preservation was observed after fixation in a buffered solution of glutaraldehyde plus acrolein without addition of heavy metals. OsO4 and particularly KMnO4 partially dissolve the biocrystallites as well as synthetic BaSO4. The crystal solubility must be taken into consideration when micrographs of such small crystallites are interpreted.The fact that BaSO4 is chemically very inert seems to exclude biochemical interactions of the statoliths with other cell components during graviperception. It favours the theory that only the mass of the statoliths is effective.

  13. Maternal Responsiveness and Sensitivity Re-Considered: Some Is More

    PubMed Central

    Bornstein, Marc H.; Manian, Nanmathi

    2013-01-01

    Is it always or necessarily the case that common and important parenting practices are better insofar as they occur more often, or worse because they occur less often? Perhaps, less is more, or some is more. To address this question, we studied mothers’ microcoded contingent responsiveness to their infants (M = 5.4 months, SD = 0.2) in relation to independent global judgments of the same mothers’ parenting sensitivity. In a community sample of 335 European American dyads, videorecorded infant and maternal behaviors were timed microanalytically throughout an extended home observation; separately and independently, global maternal sensitivity was rated macroanalytically. Sequential analysis and spline regression showed that, as maternal contingent responsiveness increased, judged maternal sensitivity increased to significance on the contingency continuum, after which mothers who were even more contingent were judged less sensitive. Just significant levels of maternal responsiveness are deemed optimally sensitive. Implications of these findings for typical and atypical parenting, child development, and intervention science are discussed. PMID:24229542

  14. Spectroscopic, structural characterizations and antioxidant capacity of the chromium (III) niacinamide compound as a diabetes mellitus drug model

    NASA Astrophysics Data System (ADS)

    Refat, Moamen S.; El-Megharbel, Samy M.; Hussien, M. A.; Hamza, Reham Z.; Al-Omar, Mohamed A.; Naglah, Ahmed M.; Afifi, Walid M.; Kobeasy, Mohamed I.

    2017-02-01

    New binuclear chromium (III) niacinamide compound with chemical formula [Cr2(Nic)(Cl)6(H2O)4]·H2O was obtained upon the reaction of chromium (III) chloride with niacinamide (Nic) in methanol solvent at 60 °C. The proposed structure was discussed with the help of microanalytical analyses, conductivity, spectroscopic (FT-IR and UV-vis.), magnetic calculations, thermogravimetric analyses (TG/TGA), and morphological studies (X-ray of solid powder and scan electron microscopy. The infrared spectrum of free niacinamide in comparison with its chromium (III) compound indicated that the chelation mode occurs via both nitrogen atoms of pyridine ring and primary -NH2 group. The efficiency of chromium (III) niacinamide compound in decreasing of glucose level of blood and HbA1c in case of diabetic rats was checked. The ameliorating gluconeogenic enzymes, lipid profile and antioxidant defense capacities are considered as an indicator of the efficiency of new chromium (III) compound as antidiabetic drug model.

  15. Development and Characterization of a Voltammetric Carbon-fiber Microelectrode pH Sensor

    PubMed Central

    Makos, Monique A.; Omiatek, Donna M.; Ewing, Andrew G.; Heien, Michael L.

    2010-01-01

    This work describes the development and characterization of a modified carbon-fiber microelectrode sensor capable of measuring real-time physiological pH changes in biological microenvironments. The reagentless sensor was fabricated under ambient conditions from voltammetric reduction of the diazonium salt Fast Blue RR onto a carbon-fiber surface in aprotic media. Fast-scan cyclic voltammetry was used to probe redox activity of the p-quinone moiety of the surface-bound molecule as a function of pH. In vitro calibration of the sensor in solutions ranging from pH 6.5 to 8.0 resulted in a pH-dependent anodic peak potential response. Flow-injection analysis was used to characterize the modified microelectrode, revealing sensitivity to acidic and basic changes discernable to 0.005 pH units. Furthermore, the modified electrode was used to measure dynamic in vivo pH changes evoked during neurotransmitter release in the central nervous system of the microanalytical model organism Drosophila melanogaster. PMID:20380393

  16. Rapid prototyping facility for flight research in artificial-intelligence-based flight systems concepts

    NASA Technical Reports Server (NTRS)

    Duke, E. L.; Regenie, V. A.; Deets, D. A.

    1986-01-01

    The Dryden Flight Research Facility of the NASA Ames Research Facility of the NASA Ames Research Center is developing a rapid prototyping facility for flight research in flight systems concepts that are based on artificial intelligence (AI). The facility will include real-time high-fidelity aircraft simulators, conventional and symbolic processors, and a high-performance research aircraft specially modified to accept commands from the ground-based AI computers. This facility is being developed as part of the NASA-DARPA automated wingman program. This document discusses the need for flight research and for a national flight research facility for the rapid prototyping of AI-based avionics systems and the NASA response to those needs.

  17. Facilities Performance Indicators Report, 2008-09

    ERIC Educational Resources Information Center

    Hills, Christina, Ed.

    2010-01-01

    This paper features another expanded Web-based Facilities Performance Indicators Report (FPI). The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. The 2008-09 iteration of the Web-based Facilities Performance Indicators Survey was posted and…

  18. Lunar base launch and landing facility conceptual design, 2nd edition

    NASA Technical Reports Server (NTRS)

    1988-01-01

    This report documents the Lunar Base Launch and Landing Facility Conceptual Design study. The purpose of this study was to examine the requirements for launch and landing facilities for early lunar bases and to prepare conceptual designs for some of these facilities. The emphasis of this study is on the facilities needed from the first manned landing until permanent occupancy. Surface characteristics and flight vehicle interactions are described, and various facility operations are related. Specific recommendations for equipment, facilities, and evolutionary planning are made, and effects of different aspects of lunar development scenarios on facilities and operations are detailed. Finally, for a given scenario, a specific conceptual design is developed and presented.

  19. Magma decompression rates during explosive eruptions of Kīlauea volcano, Hawaii, recorded by melt embayments

    USGS Publications Warehouse

    Ferguson, David J.; Gonnermann, Helge M.; Ruprecht, Philipp; Plank, Terry; Hauri, Erik H.; Houghton, Bruce F.; Swanson, Donald A.

    2016-01-01

    The decompression rate of magma as it ascends during volcanic eruptions is an important but poorly constrained parameter that controls many of the processes that influence eruptive behavior. In this study, we quantify decompression rates for basaltic magmas using volatile diffusion in olivine-hosted melt tubes (embayments) for three contrasting eruptions of Kīlauea volcano, Hawaii. Incomplete exsolution of H2O, CO2, and S from the embayment melts during eruptive ascent creates diffusion profiles that can be measured using microanalytical techniques, and then modeled to infer the average decompression rate. We obtain average rates of ~0.05–0.45 MPa s−1 for eruptions ranging from Hawaiian style fountains to basaltic subplinian, with the more intense eruptions having higher rates. The ascent timescales for these magmas vary from around ~5 to ~36 min from depths of ~2 to ~4 km, respectively. Decompression-exsolution models based on the embayment data also allow for an estimate of the mass fraction of pre-existing exsolved volatiles within the magma body. In the eruptions studied, this varies from 0.1 to 3.2 wt% but does not appear to be the key control on eruptive intensity. Our results do not support a direct link between the concentration of pre-eruptive volatiles and eruptive intensity; rather, they suggest that for these eruptions, decompression rates are proportional to independent estimates of mass discharge rate. Although the intensity of eruptions is defined by the discharge rate, based on the currently available dataset of embayment analyses, it does not appear to scale linearly with average decompression rate. This study demonstrates the utility of the embayment method for providing quantitative constraints on magma ascent during explosive basaltic eruptions.

  20. Magma decompression rates during explosive eruptions of Kīlauea volcano, Hawaii, recorded by melt embayments

    NASA Astrophysics Data System (ADS)

    Ferguson, David J.; Gonnermann, Helge M.; Ruprecht, Philipp; Plank, Terry; Hauri, Erik H.; Houghton, Bruce F.; Swanson, Donald A.

    2016-10-01

    The decompression rate of magma as it ascends during volcanic eruptions is an important but poorly constrained parameter that controls many of the processes that influence eruptive behavior. In this study, we quantify decompression rates for basaltic magmas using volatile diffusion in olivine-hosted melt tubes (embayments) for three contrasting eruptions of Kīlauea volcano, Hawaii. Incomplete exsolution of H2O, CO2, and S from the embayment melts during eruptive ascent creates diffusion profiles that can be measured using microanalytical techniques, and then modeled to infer the average decompression rate. We obtain average rates of ~0.05-0.45 MPa s-1 for eruptions ranging from Hawaiian style fountains to basaltic subplinian, with the more intense eruptions having higher rates. The ascent timescales for these magmas vary from around ~5 to ~36 min from depths of ~2 to ~4 km, respectively. Decompression-exsolution models based on the embayment data also allow for an estimate of the mass fraction of pre-existing exsolved volatiles within the magma body. In the eruptions studied, this varies from 0.1 to 3.2 wt% but does not appear to be the key control on eruptive intensity. Our results do not support a direct link between the concentration of pre-eruptive volatiles and eruptive intensity; rather, they suggest that for these eruptions, decompression rates are proportional to independent estimates of mass discharge rate. Although the intensity of eruptions is defined by the discharge rate, based on the currently available dataset of embayment analyses, it does not appear to scale linearly with average decompression rate. This study demonstrates the utility of the embayment method for providing quantitative constraints on magma ascent during explosive basaltic eruptions.

  1. Evidence from detrital zircons for the existence of continental crust and oceans on the Earth 4.4 Gyr ago.

    PubMed

    Wilde, S A; Valley, J W; Peck, W H; Graham, C M

    2001-01-11

    No crustal rocks are known to have survived since the time of the intense meteor bombardment that affected Earth between its formation about 4,550 Myr ago and 4,030 Myr, the age of the oldest known components in the Acasta Gneiss of northwestern Canada. But evidence of an even older crust is provided by detrital zircons in metamorphosed sediments at Mt Narryer and Jack Hills in the Narryer Gneiss Terrane, Yilgarn Craton, Western Australia, where grains as old as approximately 4,276 Myr have been found. Here we report, based on a detailed micro-analytical study of Jack Hills zircons, the discovery of a detrital zircon with an age as old as 4,404+/-8 Myr--about 130 million years older than any previously identified on Earth. We found that the zircon is zoned with respect to rare earth elements and oxygen isotope ratios (delta18O values from 7.4 to 5.0%), indicating that it formed from an evolving magmatic source. The evolved chemistry, high delta18O value and micro-inclusions of SiO2 are consistent with growth from a granitic melt with a delta18O value from 8.5 to 9.5%. Magmatic oxygen isotope ratios in this range point toward the involvement of supracrustal material that has undergone low-temperature interaction with a liquid hydrosphere. This zircon thus represents the earliest evidence for continental crust and oceans on the Earth.

  2. Direct tandem mass spectrometry for the simultaneous assay of opioids, cocaine and metabolites in dried urine spots.

    PubMed

    Otero-Fernández, Mara; Cocho, José Ángel; Tabernero, María Jesús; Bermejo, Ana María; Bermejo-Barrera, Pilar; Moreda-Piñeiro, Antonio

    2013-06-19

    A micro-analytical method based on spotting urine samples (20μL) onto blood/urine spot collection cards followed by air-drying and extraction (dried urine spot, DUS) was developed and validated for the screening/confirmation assay of morphine, 6-methylacetylmorphine (6-MAM), codeine, cocaine and benzoylecgonine (BZE). Acetonitrile (3 mL) was found to be a useful solvent for target extraction from DUSs under an orbital-horizontal stirring at 180 rpm for 10 min. Determinations were performed by direct electrospray ionization tandem mass spectrometry (ESI-MS/MS) under positive electrospray ionization conditions, and by using multiple reaction monitoring (MRM) with one precursor ion/product ion transition for the identification and quantification (deuterated analogs of each target as internal standards) of each analyte. The limits of detection of the method were 0.26, 0.94, 1.5, 1.1, and 2.0 ng mL(-1), for cocaine, BZE, codeine, morphine and 6-MAM, respectively; whereas, relative standard deviations of intra- and inter-day precision were lower than 8 and 11%, respectively, and intra- and inter-day analytical recoveries ranged from 94±4 to 105±3%. The small volume of urine required (20 μL), combined with the simplicity of the analytical technique makes it a useful procedure for screening/quantifying drugs of abuse. The method was successfully applied to the analysis of urine from polydrug abusers. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Definition of technology development missions for early space stations orbit transfer vehicle serving. Phase 2, task 1: Space station support of operational OTV servicing

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Representative space based orbital transfer vehicles (OTV), ground based vehicle turnaround assessment, functional operational requirements and facilities, mission turnaround operations, a comparison of ground based versus space based tasks, activation of servicing facilities prior to IOC, fleet operations requirements, maintenance facilities, OTV servicing facilities, space station support requirements, and packaging for delivery are discussed.

  4. Impact of Facility- and Community-Based Peer Support Models on Maternal Uptake and Retention in Malawi's Option B+ HIV Prevention of Mother-to-Child Transmission Program: A 3-Arm Cluster Randomized Controlled Trial (PURE Malawi).

    PubMed

    Phiri, Sam; Tweya, Hannock; van Lettow, Monique; Rosenberg, Nora E; Trapence, Clement; Kapito-Tembo, Atupele; Kaunda-Khangamwa, Blessings; Kasende, Florence; Kayoyo, Virginia; Cataldo, Fabian; Stanley, Christopher; Gugsa, Salem; Sampathkumar, Veena; Schouten, Erik; Chiwaula, Levison; Eliya, Michael; Chimbwandira, Frank; Hosseinipour, Mina C

    2017-06-01

    Many sub-Saharan African countries have adopted Option B+, a prevention of mother-to-child transmission approach providing HIV-infected pregnant and lactating women with immediate lifelong antiretroviral therapy. High maternal attrition has been observed in Option B+. Peer-based support may improve retention. A 3-arm stratified cluster randomized controlled trial was conducted in Malawi to assess whether facility- and community-based peer support would improve Option B+ uptake and retention compared with standard of care (SOC). In SOC, no enhancements were made (control). In facility-based and community-based models, peers provided patient education, support groups, and patient tracing. Uptake was defined as attending a second scheduled follow-up visit. Retention was defined as being alive and in-care at 2 years without defaulting. Attrition was defined as death, default, or stopping antiretroviral therapy. Generalized estimating equations were used to estimate risk differences (RDs) in uptake. Cox proportional hazards regression with shared frailties was used to estimate hazard of attrition. Twenty-one facilities were randomized and enrolled 1269 women: 447, 428, and 394 in facilities that implemented SOC, facility-based, and community-based peer support models, respectively. Mean age was 27 years. Uptake was higher in facility-based (86%; RD: 6%, confidence interval [CI]: -3% to 15%) and community-based (90%; RD: 9%, CI: 1% to 18%) models compared with SOC (81%). At 24 months, retention was higher in facility-based (80%; RD: 13%, CI: 1% to 26%) and community-based (83%; RD: 16%, CI: 3% to 30%) models compared with SOC (66%). Facility- and community-based peer support interventions can benefit maternal uptake and retention in Option B+.

  5. A summary of existing and planned experiment hardware for low-gravity fluids research

    NASA Technical Reports Server (NTRS)

    Hill, Myron E.; O'Malley, Terence F.

    1991-01-01

    NASA's ground-based and space-based low-gravity facilities are summarized, and an overview of selected experiments that have been developed for use in these facilities is presented. A variety of ground-based facilities (drop towers and aircraft) used to conduct low-gravity experiments for in-space experimentation are described. Capabilities that are available to the researcher and future on-orbit fluids facilities are addressed. The payload bay facilities range from the completely self-contained, relatively small get-away-special canisters to the Materials Science Laboratory and to the larger Spacelab facilities that require crew interaction.

  6. A rapid prototyping facility for flight research in advanced systems concepts

    NASA Technical Reports Server (NTRS)

    Duke, Eugene L.; Brumbaugh, Randal W.; Disbrow, James D.

    1989-01-01

    The Dryden Flight Research Facility of the NASA Ames Research Facility of the NASA Ames Research Center is developing a rapid prototyping facility for flight research in flight systems concepts that are based on artificial intelligence (AI). The facility will include real-time high-fidelity aircraft simulators, conventional and symbolic processors, and a high-performance research aircraft specially modified to accept commands from the ground-based AI computers. This facility is being developed as part of the NASA-DARPA automated wingman program. This document discusses the need for flight research and for a national flight research facility for the rapid prototyping of AI-based avionics systems and the NASA response to those needs.

  7. A summary of existing and planned experiment hardware for low-gravity fluids research

    NASA Technical Reports Server (NTRS)

    Hill, Myron E.; Omalley, Terence F.

    1991-01-01

    An overview is presented of (1) existing ground-based, low gravity research facilities, with examples of hardware capabilities, and (2) existing and planned space-based research facilities, with examples of current and past flight hardware. Low-gravity, ground-based facilities, such as drop towers and aircraft, provide the experimenter with quick turnaround time, easy access to equipment, gravity levels ranging from 10(exp -2) to 10(exp -6) G, and low-gravity durations ranging from 2 to 30 sec. Currently, the only operational space-based facility is the Space Shuttle. The Shuttle's payload bay and middeck facilities are described. Existing and planned low-gravity fluids research facilities are also described with examples of experiments and hardware capabilities.

  8. Lunar base launch and landing facilities conceptual design

    NASA Technical Reports Server (NTRS)

    Phillips, Paul G.; Simonds, Charles H.; Stump, William R.

    1992-01-01

    The purpose of this study was to perform a first look at the requirements for launch and landing facilities for early lunar bases and to prepared conceptual designs for some of these facilities. The emphasis of the study is on the facilities needed from the first manned landing until permanent occupancy, the Phase 2 lunar base. Factors including surface characteristics, navigation system, engine blast effects, and expected surface operations are used to develop landing pad designs, and definitions fo various other elements of the launch and landing facilities. Finally, the dependence of the use of these elements and the evolution of the facilities are established.

  9. 47 CFR 63.22 - Facilities-based international common carriers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Facilities-based international common carriers. 63.22 Section 63.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Supplements § 63.22 Facilities-based international common carriers. The following conditions apply to...

  10. 47 CFR 63.22 - Facilities-based international common carriers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Facilities-based international common carriers. 63.22 Section 63.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Supplements § 63.22 Facilities-based international common carriers. The following conditions apply to...

  11. 47 CFR 63.22 - Facilities-based international common carriers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Facilities-based international common carriers. 63.22 Section 63.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Supplements § 63.22 Facilities-based international common carriers. The following conditions apply to...

  12. Facilities Performance Indicators Report 2013-14: Tracking Your Facilities Vital Signs

    ERIC Educational Resources Information Center

    APPA: Association of Higher Education Facilities Officers, 2015

    2015-01-01

    This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA: Association of Higher Education Facilities Officers (APPA's) Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance…

  13. Determinants and trends in health facility-based deliveries and caesarean sections among married adolescent girls in Bangladesh.

    PubMed

    Shahabuddin, A S M; Delvaux, Thérèse; Utz, Bettina; Bardají, Azucena; De Brouwere, Vincent

    2016-09-15

    To identify the determinants and measure the trends in health facility-based deliveries and caesarean sections among married adolescent girls in Bangladesh. In order to measure the trends in health facility-based deliveries and caesarean sections, Bangladesh Demographic Health Survey (BDHS) data sets were analysed (BDHS; 1993-1994, 1996-1997, 1999-2000, 2004, 2007, 2011). The BDHS 2011 data sets were analysed to identify the determinants of health facility-based deliveries and caesarean sections. A total of 2813 adolescent girls (aged 10-19 years) were included for analysis. Bivariate and multivariate analyses were performed. Health facility-based deliveries have continuously increased among adolescents in Bangladesh over the past two decades from 3% in 1993-1994 to 24.5% in 2011. Rates of population-based and facility-based caesarean sections have increased linearly among all age groups of women including adolescents. Although the country's overall (population-based) caesarean section rate among adolescents was within acceptable range (11.6%), a rate of nearly 50% health facility level caesarean sections among adolescent girls is alarming. Among adolescent girls, use of antenatal care (ANC) appeared to be the most important predictor of health facility-based delivery (OR: 4.04; 95% CI 2.73 to 5.99), whereas the wealth index appeared as the most important predictor of caesarean sections (OR: 5.7; 95% CI 2.74 to 12.1). Maternal health-related interventions should be more targeted towards adolescent girls in order to encourage them to access ANC and promote health facility-based delivery. Rising trends of caesarean sections require further investigation on indication and provider-client-related determinants of these interventions among adolescent girls in Bangladesh. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  14. Tracking Radionuclide Fractionation in the First Atomic Explosion Using Stable Elements

    DOE PAGES

    Bonamici, Chloë E.; Hervig, Richard L.; Kinman, William S.

    2017-08-25

    Compositional analysis of postdetonation fallout is a tool for forensic identification of nuclear devices. However, the relationship between device composition and fallout composition is difficult to interpret because of the complex combination of physical mixing, nuclear reactions, and chemical fractionations that occur in the chaotic nuclear fireball. By using a combination of in situ microanalytical techniques (electron microprobe analysis and secondary ion mass spectrometry), we show that some heavy stable elements (Rb, Sr, Zr, Ba, Cs, Ba, La, Ce, Nd, Sm, Dy, Lu, U, Th) in glassy fallout from the first nuclear test, Trinity, are reliable chemical proxies for radionuclidesmore » generated during the explosion. Stable-element proxies show that radionuclides from the Trinity device were chemically, but not isotopically, fractionated by condensation. Moreover, stable-element proxies delineate chemical fractionation trends that can be used to connect present-day fallout composition to past fireball composition. Stable-element proxies therefore offer a novel approach for elucidating the phenomenology of the nuclear fireball as it relates to the formation of debris and the fixation of device materials within debris.« less

  15. Achieving an empathic stance: dialogical sequence analysis of a change episode.

    PubMed

    Tikkanen, Soile; Stiles, William B; Leiman, Mikael

    2013-01-01

    Abstract This study examined a client's therapeutic progress within one session of an 18-session child neurological assessment. The analysis focused on a parent-psychologist dialogue in one session of the assessment process. Dialogical sequence analysis (DSA; Leiman, 2004, 2012) was used as a micro-analytic method to examine the developing discourse. The analysis traced the mother's developing of a reflective stance toward herself and her problematic ways of interacting with her daughter, who was the client. During the dialogue, the mother began to recognize her own contribution in maintaining the problematic pattern. Her gradual acknowledgment of the child's perspective and her growing sense of the child's otherness were mediated by an observer position (third-person view) toward the problematic pattern, which allowed a flexible exchange between the perspectives of self and the other. The results demonstrate the parallel development of intrapersonal and interpersonal empathy shown previously to characterize the transition from stage 3 (problem statement/clarification) to stage 4 (understanding/insight) in the assimilation of problematic experiences sequence (Brinegar, Salvi, Stiles, & Greenberg, 2006).

  16. Fundamentals of Passive Oxidation In SiC and Si3N4

    NASA Technical Reports Server (NTRS)

    Thomas-Ogbuji, Linus U.

    1998-01-01

    The very slow oxidation kinetics of silicon carbide and silicon nitride, which derive from their adherent and passivating oxide films, has been explored at length in a broad series of studies utilizing thermogravimetric analysis, electron and optical micrography, energy dispersive spectrometry, x-ray diffractometry, micro-analytical depth profiling, etc. Some interesting microstructural phenomena accompanying the process of oxidation in the two materials will be presented. In Si3N4 the oxide is stratified, with an SiO2 topscale (which is relatively impervious to O2)underlain by a coherent subscale of silicon oxynitride which is even less permeable to O2- Such "defence in depth" endows Si3N4 with what is perhaps the highest oxidation resistance of any material, and results in a unique set of oxidation processes. In SiC the oxidation reactions are much simpler, yet new issues still emerge; for instance, studies involving controlled devitrification of the amorphous silica scale confirmed that the oxidation rate of SiC drops by more than an order of magnitude when the oxide scale fully crystallizes.

  17. Tracking Radionuclide Fractionation in the First Atomic Explosion Using Stable Elements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bonamici, Chloë E.; Hervig, Richard L.; Kinman, William S.

    Compositional analysis of postdetonation fallout is a tool for forensic identification of nuclear devices. However, the relationship between device composition and fallout composition is difficult to interpret because of the complex combination of physical mixing, nuclear reactions, and chemical fractionations that occur in the chaotic nuclear fireball. By using a combination of in situ microanalytical techniques (electron microprobe analysis and secondary ion mass spectrometry), we show that some heavy stable elements (Rb, Sr, Zr, Ba, Cs, Ba, La, Ce, Nd, Sm, Dy, Lu, U, Th) in glassy fallout from the first nuclear test, Trinity, are reliable chemical proxies for radionuclidesmore » generated during the explosion. Stable-element proxies show that radionuclides from the Trinity device were chemically, but not isotopically, fractionated by condensation. Moreover, stable-element proxies delineate chemical fractionation trends that can be used to connect present-day fallout composition to past fireball composition. Stable-element proxies therefore offer a novel approach for elucidating the phenomenology of the nuclear fireball as it relates to the formation of debris and the fixation of device materials within debris.« less

  18. Hg localisation in Tillandsia usneoides L. (Bromeliaceae), an atmospheric biomonitor

    NASA Astrophysics Data System (ADS)

    Amado Filho, G. M.; Andrade, L. R.; Farina, M.; Malm, O.

    The Spanish moss, Tillandsia usneoides, has been applied as an atmospheric biomonitor of Hg contamination, although the mechanism of metal plant accumulation has not been understood until now. In the present work, analytical scanning electron microscopy (SEM) was used to localize Hg in T. usneoides exposed to a Hg-air-contaminated area during 15 days. After this period, Hg was determined by the flow injection mercury system, and plants were prepared for SEM observation and energy-dispersive X-ray analysis. A concentration of 2702±318 μg Hg g -1 was determined in exposed plants. The presented microanalytical results demonstrated that Hg was partly associated with atmospheric particles deposited upon the plant surface, but it was highly absorbed by the scales, stem and leaves surfaces and less absorbed by epidermal cells of T. usneoides. No Hg was detected in mesophyll parenchyma or in vascular system cells. The great surface adsorption area provided by the scales, in addition to the characteristics of T. usneoides morphology, especially of the node region, are suggested to confer the great capability of T. usneoides in Hg holding.

  19. The Space Shuttle Columbia Accident Investigation and Reconstruction: Two Years Later

    NASA Technical Reports Server (NTRS)

    McDanels, Steven J.

    2005-01-01

    The Space Shuttle Columbia was lost during re-entry over two years ago. Since the release of the official materials-related findings in August of 2003, additional testing and analysis of select pieces of debris has continued. Microanalytical techniques, including EMPA, ESCA, and x-ray elemental dot mapping, were employed during the initial investigation; the results related the microstructural characteristics of deposit layers to the breach location in the leading edge of the left wing. Such characteristics included deposition order, composition, and distribution. Subsequent to the original efforts, new analytical data and information, not available at the time of the primary investigation, has been generated. This data was obtained via a low-vacuum SEM, fitted not only with a light-element EDS detector, but an XRF tube as well. Essentially, for elements up to sodium, classic EDS was utilized; above sodium, XRF was used. Predominantly, the elements of interest were aluminum, titanium, chromium, iron, nickel, and copper. The findings of both old and new data are compared, and their application to the overall accident investigation detailed.

  20. Tracking Radionuclide Fractionation in the First Atomic Explosion Using Stable Elements.

    PubMed

    Bonamici, Chloë E; Hervig, Richard L; Kinman, William S

    2017-09-19

    Compositional analysis of postdetonation fallout is a tool for forensic identification of nuclear devices. However, the relationship between device composition and fallout composition is difficult to interpret because of the complex combination of physical mixing, nuclear reactions, and chemical fractionations that occur in the chaotic nuclear fireball. Using a combination of in situ microanalytical techniques (electron microprobe analysis and secondary ion mass spectrometry), we show that some heavy stable elements (Rb, Sr, Zr, Ba, Cs, Ba, La, Ce, Nd, Sm, Dy, Lu, U, Th) in glassy fallout from the first nuclear test, Trinity, are reliable chemical proxies for radionuclides generated during the explosion. Stable-element proxies show that radionuclides from the Trinity device were chemically, but not isotopically, fractionated by condensation. Furthermore, stable-element proxies delineate chemical fractionation trends that can be used to connect present-day fallout composition to past fireball composition. Stable-element proxies therefore offer a novel approach for elucidating the phenomenology of the nuclear fireball as it relates to the formation of debris and the fixation of device materials within debris.

  1. Solving mercury (Hg) speciation in soil samples by synchrotron X-ray microspectroscopic techniques.

    PubMed

    Terzano, Roberto; Santoro, Anna; Spagnuolo, Matteo; Vekemans, Bart; Medici, Luca; Janssens, Koen; Göttlicher, Jörg; Denecke, Melissa A; Mangold, Stefan; Ruggiero, Pacifico

    2010-08-01

    Direct mercury (Hg) speciation was assessed for soil samples with a Hg concentration ranging from 7 up to 240 mg kg(-1). Hg chemical forms were identified and quantified by sequential extractions and bulk- and micro-analytical techniques exploiting synchrotron generated X-rays. In particular, microspectroscopic techniques such as mu-XRF, mu-XRD and mu-XANES were necessary to solve bulk Hg speciation, in both soil fractions <2 mm and <2 microm. The main Hg-species found in the soil samples were metacinnabar (beta-HgS), cinnabar (alpha-HgS), corderoite (Hg(3)S(2)Cl(2)), and an amorphous phase containing Hg bound to chlorine and sulfur. The amount of metacinnabar and amorphous phases increased in the fraction <2 microm. No interaction among Hg-species and soil components was observed. All the observed Hg-species originated from the slow weathering of an inert Hg-containing waste material (K106, U.S. EPA) dumped in the area several years ago, which is changing into a relatively more dangerous source of pollution. Copyright 2010 Elsevier Ltd. All rights reserved.

  2. A microanalytical method for ammonium and short-chain primary aliphatic amines using precolumn derivatization and capillary liquid chromatography.

    PubMed

    Moliner-Martínez, Y; Herráez-Hernández, R; Campíns-Falcó, P

    2007-09-14

    A new microscale method is presented for the determination of ammonium and primary short-chain aliphatic amines (methylamine, ethylamine, propylamine, n-butylamine and n-pentylamine) in water. The assay uses precolumn derivatization with the reagent o-phthaldialdehyde (OPA) in combination with the thiol N-acetyl-L-cysteine (NAC), and capillary liquid chromatography with UV detection at 330 nm. The described method is very simple and rapid as no preconcentration of the analytes is necessary, and the volume of sample required is only 0.1 mL. Under the proposed conditions good linearity has been obtained up to a concentration of the analytes of 10.0 mgL(-1), the limits of detection being of 8-50 microgL(-1). No matrix effect was found, and recoveries between 97 and 110% were obtained. The precision of the method was good, and the achieved variation coefficients were below 12%. The reliability of the proposed approach has been tested by analyzing a microsample of fogwater collected from leaf surfaces.

  3. A case series study on the effect of Ebola on facility-based deliveries in rural Liberia.

    PubMed

    Lori, Jody R; Rominski, Sarah Danielson; Perosky, Joseph E; Munro, Michelle L; Williams, Garfee; Bell, Sue Anne; Nyanplu, Aloysius B; Amarah, Patricia N M; Boyd, Carol J

    2015-10-12

    As communities' fears of Ebola virus disease (EVD) in West Africa exacerbate and their trust in healthcare providers diminishes, EVD has the potential to reverse the recent progress made in promoting facility-based delivery. Using retrospective data from a study focused on maternal and newborn health, this analysis examined the influence of EVD on the use of facility-based maternity care in Bong Country, Liberia, which shares a boarder with Sierra Leone - near the epicenter of the outbreak. Using a case series design, retrospective data from logbooks were collected at 12 study sites in one county. These data were then analyzed to determine women's use of facility-based maternity care between January 2012 and October 2014. The primary outcome was the number of facility-based deliveries over time. The first suspected case of EVD in Bong County was reported on June 30, 2014. Heat maps were generated and the number of deliveries was normalized to the average number of deliveries during the full 12 months before the EVD outbreak (March 2013 - February 2014). Prior to the EVD outbreak, facility-based deliveries steadily increased in Bong County reaching an all-time high of over 500 per month at study sites in the first half of 2014 - indicating Liberia was making inroads in normalizing institutional maternal healthcare. However, as reports of EVD escalated, facility-based deliveries decreased to a low of 113 in August 2014. Ebola virus disease has negatively impacted the use of facility-based maternity services, placing childbearing women at increased risk for morbidity and death.

  4. Facility-based delivery in the context of Zimbabwe's HIV epidemic--missed opportunities for improving engagement with care: a community-based serosurvey.

    PubMed

    Buzdugan, Raluca; McCoy, Sandra I; Webb, Karen; Mushavi, Angela; Mahomva, Agnes; Padian, Nancy S; Cowan, Frances M

    2015-12-17

    In developing countries, facility-based delivery is recommended for maternal and neonatal health, and for prevention of mother-to-child HIV transmission (PMTCT). However, little is known about whether or not learning one's HIV status affects one's decision to deliver in a health facility. We examined this association in Zimbabwe. We analyzed data from a 2012 cross-sectional community-based serosurvey conducted to evaluate Zimbabwe's accelerated national PMTCT program. Eligible women (≥16 years old and mothers of infants born 9-18 months before the survey) were randomly sampled from the catchment areas of 157 health facilities in five of ten provinces. Participants were interviewed about where they delivered and provided blood samples for HIV testing. Overall 8796 (77 %) mothers reported facility-based delivery; uptake varied by community (30-100%). The likelihood of facility-based delivery was not associated with maternal HIV status. Women who self-reported being HIV-positive before delivery were as likely to deliver in a health facility as women who were HIV-negative, irrespective of when they learned their status - before (adjusted prevalence ratio (PRa) = 1.04, 95% confidence interval (CI) = 1.00-1.09) or during pregnancy (PRa = 1.05, 95% CI = 1.01-1.09). Mothers who had not accessed antenatal care or tested for HIV were most likely to deliver outside a health facility (69%). Overall, however 77% of home deliveries occurred among women who had accessed antenatal care and were HIV-tested. Uptake of facility-based delivery was similar among HIV-infected and HIV-uninfected mothers, which was somewhat unexpected given the substantial technical and financial investment aimed at retaining HIV-positive women in care in Zimbabwe.

  5. New spatial clustering-based models for optimal urban facility location considering geographical obstacles

    NASA Astrophysics Data System (ADS)

    Javadi, Maryam; Shahrabi, Jamal

    2014-03-01

    The problems of facility location and the allocation of demand points to facilities are crucial research issues in spatial data analysis and urban planning. It is very important for an organization or governments to best locate its resources and facilities and efficiently manage resources to ensure that all demand points are covered and all the needs are met. Most of the recent studies, which focused on solving facility location problems by performing spatial clustering, have used the Euclidean distance between two points as the dissimilarity function. Natural obstacles, such as mountains and rivers, can have drastic impacts on the distance that needs to be traveled between two geographical locations. While calculating the distance between various supply chain entities (including facilities and demand points), it is necessary to take such obstacles into account to obtain better and more realistic results regarding location-allocation. In this article, new models were presented for location of urban facilities while considering geographical obstacles at the same time. In these models, three new distance functions were proposed. The first function was based on the analysis of shortest path in linear network, which was called SPD function. The other two functions, namely PD and P2D, were based on the algorithms that deal with robot geometry and route-based robot navigation in the presence of obstacles. The models were implemented in ArcGIS Desktop 9.2 software using the visual basic programming language. These models were evaluated using synthetic and real data sets. The overall performance was evaluated based on the sum of distance from demand points to their corresponding facilities. Because of the distance between the demand points and facilities becoming more realistic in the proposed functions, results indicated desired quality of the proposed models in terms of quality of allocating points to centers and logistic cost. Obtained results show promising improvements of the allocation, the logistics costs and the response time. It can also be inferred from this study that the P2D-based model and the SPD-based model yield similar results in terms of the facility location and the demand allocation. It is noted that the P2D-based model showed better execution time than the SPD-based model. Considering logistic costs, facility location and response time, the P2D-based model was appropriate choice for urban facility location problem considering the geographical obstacles.

  6. QACD: A method for the quantitative assessment of compositional distribution in geologic materials

    NASA Astrophysics Data System (ADS)

    Loocke, M. P.; Lissenberg, J. C. J.; MacLeod, C. J.

    2017-12-01

    In order to fully understand the petrogenetic history of a rock, it is critical to obtain a thorough characterization of the chemical and textural relationships of its mineral constituents. Element mapping combines the microanalytical techniques that allow for the analysis of major- and minor elements at high spatial resolutions (e.g., electron microbeam analysis) with 2D mapping of samples in order to provide unprecedented detail regarding the growth histories and compositional distributions of minerals within a sample. We present a method for the acquisition and processing of large area X-ray element maps obtained by energy-dispersive X-ray spectrometer (EDS) to produce a quantitative assessment of compositional distribution (QACD) of mineral populations within geologic materials. By optimizing the conditions at which the EDS X-ray element maps are acquired, we are able to obtain full thin section quantitative element maps for most major elements in relatively short amounts of time. Such maps can be used to not only accurately identify all phases and calculate mineral modes for a sample (e.g., a petrographic thin section), but, critically, enable a complete quantitative assessment of their compositions. The QACD method has been incorporated into a python-based, easy-to-use graphical user interface (GUI) called Quack. The Quack software facilitates the generation of mineral modes, element and molar ratio maps and the quantification of full-sample compositional distributions. The open-source nature of the Quack software provides a versatile platform which can be easily adapted and modified to suit the needs of the user.

  7. Studies of Scale Formation and Kinetics of Crofer 22 APU and Haynes 230 in Carbon Oxide-Containing Environment for SOFC Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ziomek-Moroz, M.; Covino, B.S., Jr.; Holcomb, G.R.

    2006-01-01

    Significant progress in reducing the operating temperature of SOFCs below 800oC may allow the use of chromia-forming metallic interconnects at a substantial cost savings. Hydrogen is the main fuel for all types of fuel cells except direct methanol fuel cells. Hydrogen can be generated from fossil fuels, including coal, natural gas, diesel, gasoline, other hydrocarbons, and oxygenates (e.g., methanol, ethanol, butanol, etc.). Carbon oxides present in the hydrogen fuel can cause significant performance problems due to carbon formation (coking). Also, literature data indicate that in CO/CO2 gaseous environments, metallic materials that gain their corrosion resistance due to formation of Cr2O3,more » could form stable chromium carbides. The chromium carbide formation causes depletion of chromium in these alloys. If the carbides oxidize, they form non-protective scales. Considering a potential detrimental effect of carbon oxides on iron- and nickel-base alloy stability, determining corrosion performance of metallic interconnect candidates in carbon oxide-containing environments at SOFC operating temperatures is a must. In this research, the corrosion behavior of Crofer 22 APU and Haynes 230 was studied in a CO-rich atmosphere at 750°C. Chemical composition of the gaseous environment at the outlet was determined using gas chromatography (GC). After 800 h of exposure to the gaseous environment the surfaces of the corroded samples were studied by scanning electron microscopy (SEM) equipped with microanalytical capabilities. X-ray diffraction (XRD) analysis was also used in this study.« less

  8. Synthesis, molecular and crystalline architectures, and properties of mononuclear cobalt(II)thiocyanates containing a symmetrical tailored diimine/an unsymmetrical bidentate Schiff base

    NASA Astrophysics Data System (ADS)

    Sarkar, Bhola Nath; Bhar, Kishalay; Kundu, Subhasis; Fun, Hoong-Kun; Ghosh, Barindra Kumar

    2009-11-01

    Two hexacoordinated mononuclear cobalt(II)thiocyanate complexes of general formula [Co(LL) 2(NCS) 2]. nH 2O [LL = 2,2'-dipyridylamine (dpa), n = 1, 1; LL = N-((pyridin-2-yl)benzylidene)benzylamine (pbba), n = 0, 2] have been prepared and characterized using microanalytical, spectroscopic and other physicochemical results. The compounds are non-electrolytes and behave as three-electron paramagnets. Structures of 1 and 2 are solved by X-ray diffraction measurements. Structural analyses show that each metal center in 1 and 2 adopts a distorted octahedral geometry with a CoN 6 chromophore ligated through four N atoms of two bidentate LL units; the hexacoordination is completed by two N atoms of terminal thiocyanates in mutual cis orientation. The mononuclear units in 1 are engaged in weak intermolecular N-H…S and C-H…S hydrogen bonds to give a 2D sheet structure, which is further stabilized by π…π interactions among the pyridine rings of dpa units. In the long-range form, two mononuclear units of 2 are locked by weak doubly C-H…S hydrogen bonds producing a dimeric unit, which packs through C-H…π interaction leading to a 2D continuum. In MeCN solutions, the compounds show a nearly reversible one-electron oxidative response corresponding to cobalt(III)-cobalt(II) couple. The complexes display intraligand 1(π-π∗) fluorescence at room temperature and intraligand 3(π-π∗) phosphorescence in glassy solutions (DMF at 77 K).

  9. Reliable Facility Location Problem with Facility Protection

    PubMed Central

    Tang, Luohao; Zhu, Cheng; Lin, Zaili; Shi, Jianmai; Zhang, Weiming

    2016-01-01

    This paper studies a reliable facility location problem with facility protection that aims to hedge against random facility disruptions by both strategically protecting some facilities and using backup facilities for the demands. An Integer Programming model is proposed for this problem, in which the failure probabilities of facilities are site-specific. A solution approach combining Lagrangian Relaxation and local search is proposed and is demonstrated to be both effective and efficient based on computational experiments on random numerical examples with 49, 88, 150 and 263 nodes in the network. A real case study for a 100-city network in Hunan province, China, is presented, based on which the properties of the model are discussed and some managerial insights are analyzed. PMID:27583542

  10. Fire safety of ground-based space facilities on the spaceport ;Vostochny;

    NASA Astrophysics Data System (ADS)

    Artamonov, Vladimir S.; Gordienko, Denis M.; Melikhov, Anatoly S.

    2017-06-01

    The facilities of the spaceport ;Vostochny; and the innovative technologies for fire safety to be implemented are considered. The planned approaches and prospects for fire safety ensuring at the facilities of the spaceport ;Vostochny; are presented herein, based on the study of emergency situations having resulted in fire accidents and explosion cases at the facilities supporting space vehicles operation.

  11. 18. Topside facility, interior of facility manager's room, view towards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Topside facility, interior of facility manager's room, view towards west. Lyon - Whiteman Air Force Base, Oscar O-1 Minuteman Missile Alert Facility, Southeast corner of Twelfth & Vendenberg Avenues, Knob Noster, Johnson County, MO

  12. A distributed data base management facility for the CAD/CAM environment

    NASA Technical Reports Server (NTRS)

    Balza, R. M.; Beaudet, R. W.; Johnson, H. R.

    1984-01-01

    Current/PAD research in the area of distributed data base management considers facilities for supporting CAD/CAM data management in a heterogeneous network of computers encompassing multiple data base managers supporting a variety of data models. These facilities include coordinated execution of multiple DBMSs to provide for administration of and access to data distributed across them.

  13. 33 CFR 157.304 - Shore-based reception facility: standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Shore-based reception facility: standards. 157.304 Section 157.304 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... CARRYING OIL IN BULK Exemption From § 157.10a or § 157.10c § 157.304 Shore-based reception facility...

  14. 33 CFR 157.304 - Shore-based reception facility: standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Shore-based reception facility: standards. 157.304 Section 157.304 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... CARRYING OIL IN BULK Exemption From § 157.10a or § 157.10c § 157.304 Shore-based reception facility...

  15. Facilities Performance Indicators Report 2012-13: Tracking Your Facilities Vital Signs

    ERIC Educational Resources Information Center

    APPA: Association of Higher Education Facilities Officers, 2014

    2014-01-01

    This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance Indicators Report" is designed for survey…

  16. Comparing the nutrition environment and practices of home- and centre-based child-care facilities.

    PubMed

    Martyniuk, Olivia J M; Vanderloo, Leigh M; Irwin, Jennifer D; Burke, Shauna M; Tucker, Patricia

    2016-03-01

    To assess and compare the nutrition environment and practices (as they relate to pre-schoolers) of centre- and home-based child-care facilities. Using a cross-sectional study design, nineteen child-care facilities (ten centre-based, nine home-based) were assessed for one full day using the Environment and Policy Assessment and Observation (EPAO) tool (consisting of a day-long observation/review of the nutrition environment, practices and related documents). Specifically, eight nutrition-related subscales were considered. Child-care facilities in London, Ontario, Canada. Child-care facilities were recruited through directors at centre-based programmes and the providers of home-based programmes. The mean total nutrition environment EPAO scores for centre- and home-based facilities were 12·3 (sd 1·94) and 10·8 (sd 0·78) out of 20 (where a higher score indicates a more supportive environment with regard to nutrition), respectively. The difference between the total nutrition environment EPAO score for centre- and home-based facilities was approaching significance (P=0·055). For both types of facilities, the highest nutrition subscale score (out of 20) was achieved in the staff behaviours domain (centre mean=17·4; home mean=17·0) and the lowest was in the nutrition training and education domain (centre mean=3·6; home mean=2·0). Additional research is needed to confirm these findings. In order to better support child-care staff and enhance the overall nutrition environment in child care, modifications to food practices could be adopted. Specifically, the nutritional quality of foods/beverages provided to pre-schoolers could be improved, nutrition-related training for child-care staff could be provided, and a nutrition curriculum could be created to educate pre-schoolers about healthy food choices.

  17. A First Look at PCMH Implementation for Minority Veterans: Room for Improvement.

    PubMed

    Hernandez, Susan E; Taylor, Leslie; Grembowski, David; Reid, Robert J; Wong, Edwin; Nelson, Karin M; Liu, Chuan-Fen; Fihn, Stephan D; Hebert, Paul L

    2016-03-01

    Implementation of Patient Aligned Care Teams (PACT), a patient-centered medical home model, has been inconsistent among the >900 primary care facilities in the Veterans Health Administration. Estimate if the degree of PACT implementation at a facility varied with the percentage of minority veteran patients at the facility. Cross-sectional, facility-level analysis of PACT implementation measures in 2012. Veterans Health Administration hospital-based and community-based primary care facilities. We used a previously validated PACT Implementation Progress Index (Pi) and its 8 domains: access, continuity of care, care coordination, comprehensiveness, self-management support, and patient-centered care and communication, shared decision-making domains, and team functioning. Facilities were categorized as low (<5.2%, n=208), medium (5.2%-25.8%, n=413), and high (>25.8%, n=206) percent minority based on the percent of their own veteran population. Most minority veterans received care in high minority (69%) and medium minority facilities (29%). In adjusted analyses, medium and high minority facilities scored 0.773 (P=0.009) and 0.930 (P=0.008) points lower on the Pi score relative to low minority facilities. Relative to low minority facilities, both medium and high minority facilities were less likely of having high Pi scores (≥2) and more likely of having low Pi scores (≤-2). Both medium and high minority facilities had the same 3 domain scores lower than low minority facilities (care coordination, comprehensiveness, and self-management). Overall PACT implementation varied with respect to the racial/ethnic composition of a facility, with medium and high minority facilities having a lower implementation scores.

  18. Proposal for a new categorization of aseptic processing facilities based on risk assessment scores.

    PubMed

    Katayama, Hirohito; Toda, Atsushi; Tokunaga, Yuji; Katoh, Shigeo

    2008-01-01

    Risk assessment of aseptic processing facilities was performed using two published risk assessment tools. Calculated risk scores were compared with experimental test results, including environmental monitoring and media fill run results, in three different types of facilities. The two risk assessment tools used gave a generally similar outcome. However, depending on the tool used, variations were observed in the relative scores between the facilities. For the facility yielding the lowest risk scores, the corresponding experimental test results showed no contamination, indicating that these ordinal testing methods are insufficient to evaluate this kind of facility. A conventional facility having acceptable aseptic processing lines gave relatively high risk scores. The facility showing a rather high risk score demonstrated the usefulness of conventional microbiological test methods. Considering the significant gaps observed in calculated risk scores and in the ordinal microbiological test results between advanced and conventional facilities, we propose a facility categorization based on risk assessment. The most important risk factor in aseptic processing is human intervention. When human intervention is eliminated from the process by advanced hardware design, the aseptic processing facility can be classified into a new risk category that is better suited for assuring sterility based on a new set of criteria rather than on currently used microbiological analysis. To fully benefit from advanced technologies, we propose three risk categories for these aseptic facilities.

  19. Experimental Fuels Facility Re-categorization Based on Facility Segmentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reiss, Troy P.; Andrus, Jason

    The Experimental Fuels Facility (EFF) (MFC-794) at the Materials and Fuels Complex (MFC) located on the Idaho National Laboratory (INL) Site was originally constructed to provide controlled-access, indoor storage for radiological contaminated equipment. Use of the facility was expanded to provide a controlled environment for repairing contaminated equipment and characterizing, repackaging, and treating waste. The EFF facility is also used for research and development services, including fuel fabrication. EFF was originally categorized as a LTHC-3 radiological facility based on facility operations and facility radiological inventories. Newly planned program activities identified the need to receive quantities of fissionable materials in excessmore » of the single parameter subcritical limit in ANSI/ANS-8.1, “Nuclear Criticality Safety in Operations with Fissionable Materials Outside Reactors” (identified as “criticality list” quantities in DOE-STD-1027-92, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports,” Attachment 1, Table A.1). Since the proposed inventory of fissionable materials inside EFF may be greater than the single parameter sub-critical limit of 700 g of U-235 equivalent, the initial re-categorization is Hazard Category (HC) 2 based upon a potential criticality hazard. This paper details the facility hazard categorization performed for the EFF. The categorization was necessary to determine (a) the need for further safety analysis in accordance with LWP-10802, “INL Facility Categorization,” and (b) compliance with 10 Code of Federal Regulations (CFR) 830, Subpart B, “Safety Basis Requirements.” Based on the segmentation argument presented in this paper, the final hazard categorization for the facility is LTHC-3. Department of Energy Idaho (DOE-ID) approval of the final hazard categorization determined by this hazard assessment document (HAD) was required per the DOE-ID Supplemental Guidance for DOE-STD-1027-92 based on the proposed downgrade of the initial facility categorization of Hazard Category 2.« less

  20. Planning of dairy farm and dairy plant based ecotourism

    NASA Astrophysics Data System (ADS)

    Sarnyoto, A. S.; Tama, I. P.; Tantrika, C. F. M.

    2017-06-01

    One of a dairy production company producing pasteurized milk and yoghurt drink, whose brand has widely known in East Java, has a factory plant in Batu City, one of tourism destinations in Indonesia. Behind the factory plant, there is a vacant land with an estimated total area of 2.3 ha and a vacant cowshed which had not been used for cattle ranching. Because of that, the company planned to develop the vacant land as a dairy farm and plant based ecotourism. In addition, dairy farm and dairy plant based tourism attractions are still rarely found in Batu. Thus, the first aim of this study was to analyse the potencies of the company that related to future plans of ecotourism built. The second aim was to set up the strategies that can be done in order to actualize the ecotourism project. The next aim was to plan the ecotourism, especially the facilities planning and the facilities arrangement on the vacant land. Strategic management approach was used to analyse the potencies and to determine the strategies. To select the proper facilities, tourists were asked to give appraisal by using questionnaire. Appraisal result was mapped onto four quadrants spatial map to see advantages and shortcomings of each facility along with choosing the right facilities to be built. Those facilities and tourist activities were compared with ecotourism criteria to make sure that the facilities were appropriate to provide not only entertainment but also ecotourism function. To arrange the chosen facilities, the step in Systematic Layout Planning were conducted to generate a propose layout of facilities arrangement. Based on potencies analysis, in Internal-External matrix, the company current position was on quadrant 2 (grow and build), with the most appropriate strategy was intensive or integrative. The proposed strategies were to build the new infrastructure, to renovate cowshed, and to add new tourism facilities on the land. There were 11 selected facilities based on MDS. Moreover, based on SLP, a facility layout had been designed and been proposed to be built on the vacant land behind the factory as the new ecotourism destination.

  1. [The situation and associated factors of facility-based HIV testing among men who sex with men in Beijing].

    PubMed

    Ren, X L; Mi, G D; Zhao, Y; Rou, K M; Zhang, D P; Geng, L; Chen, Z H; Wu, Z Y

    2017-04-06

    Objective: To understand the prevalence of facility-based HIV testing and its associated factors among men who have sex with men (MSM) in Beijing city. Methods: An application-based cross-sectional survey was employed to understand HIV site test situation and associated factors. The survey was carried out from May 14(th) to 21(st), 2016. Users of a smart phone application for gay dating were recruited and those eligible for this survey were investigated with an online self-administered questionnaire. Information of demographics, sexual behaviors, facility-based HIV testing history and recreational drug abuses were collected. The multivariate logistic regression was used to make comparison among different groups and assess associated factors. Results: A total of 7 494 participants were enrolled in the survey with mean age of (28.81 ± 7.38) years, 87.14% (6 530/7 494) sought sexual partners through internet. The proportion of facility-based HIV testing in 1 year was 42.55% (3 189/7 494), MSM who were 25-29 years had higher proportion of facility-based HIV testing in 1 year, the proportion was 45.56%(1 104/2 423). Among MSM who could insist in using condom during anal sex (50.46% (1 539/3 050)), the proportion of HIV site testing in 1 year was higher. The MSM who reported seeking healthcare for symptoms of a sexually transmitted infections (STIs) in the past year or ever using recreational drug had higher proportion of facility-based HIV testing, the proportions were 56.81% (409/720) and 52.00% (1 340/4 917), respectively. Compared with alone cohabitation, cohabitating was associated with decreased odds of HIV facility-based testing in past 1 year(odds ratio ( OR )= 0.79, P< 0.001). Compared with homosexual sexual orientation, bisexual sexual orientation was associated with decreased odds of facility-based HIV testing ( OR= 0.83, P= 0.004). With the increasing of number of male anal sex partners, the odds of HIV facility-based testing was increasing ( OR= 1.31, P< 0.001) But with the decreasing of the frequency of condom using with male anal sex partners, the odds of facility-based HIV testing was decreasing ( OR= 0.85, P= 0.014). Using recreational drugs ( OR= 1.36, P< 0.001) and seeking healthcare for symptoms of a STI in the past 1 year ( OR= 1.73, P< 0.001) were associated with decreased odds of HIV site testing. Conclusion: MSM in Beijing had lower proportion of facility-based HIV testing in past 1 year. Multiple anal sex partners, using recreational drugs, seeking healthcare for symptoms of a STI in the past year, cohabitating, bisexual sexual orientation, and lower frequency of condom using with male anal sex partners were associated with the odds of HIV facility-based testing in past 1 year.

  2. A novel method for designing and optimizing the layout of facilities in bathroom for the elderly in home-based rehabilitation.

    PubMed

    Wang, Duojin; Wu, Jing; Lin, Qinglian

    2018-05-01

    The home-based rehabilitation of elderly patients improves their autonomy, independence and reintegration into society. Hence, a suitable environment plays an important role in rehabilitation, as do different assistance technologies. The majority of accidents at home involving elderly people occur in the bathroom. Therefore, the planning of the layout of facilities is important in this potentially dangerous area. This paper proposes an approach towards designing and optimizing the layout of facilities in the bathroom, based on logistical and nonlogistical relationships. A fuzzy-based analytical hierarchical process (fuzzy-AHP) is then proposed for a comprehensive evaluation of the alternatives for this layout plan. This approach was applied to the home of a 71 years old female patient, who was experiencing home-based rehabilitation. After the initial designing and optimizing of the layout of the facilities in her bathroom, a plan could then be created for her particular needs. The results of this research could then enable the home-based rehabilitation of elderly patients to be more effective. Value: This paper develops a new approach to design and optimize the layout of facilities in bathroom for the elderly. Implications for Rehabilitation Develop a new approach to design and optimize the layout of facilities in bathroom. Provide a mathematical and more scientific approach to home layout design for home-based rehabilitation. Provide new opportunities for research, for both the therapist and the patient to analyse the home facility layout.

  3. 10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

  4. 10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

  5. 10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

  6. 10 CFR 70.64 - Requirements for new facilities or new processes at existing facilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... behavior of items relied on for safety. (b) Facility and system design and facility layout must be based on... existing facilities. (a) Baseline design criteria. Each prospective applicant or licensee shall address the following baseline design criteria in the design of new facilities. Each existing licensee shall address the...

  7. Facilities Performance Indicators Report, 2004-05. Facilities Core Data Survey

    ERIC Educational Resources Information Center

    Glazner, Steve, Ed.

    2006-01-01

    The purpose of "Facilities Performance Indicators" is to provide a representative set of statistics about facilities in educational institutions. The second iteration of the web-based Facilities Core Data Survey was posted and available to facilities professionals at more than 3,000 institutions in the Fall of 2005. The website offered a printed…

  8. Cost and cost-effectiveness of community based and health facility based directly observed treatment of tuberculosis in Dar es Salaam, Tanzania

    PubMed Central

    Wandwalo, Eliud; Robberstad, Bjarne; Morkve, Odd

    2005-01-01

    Background Identifying new approaches to tuberculosis treatment that are effective and put less demand to meagre health resources is important. One such approach is community based direct observed treatment (DOT). The purpose of the study was to determine the cost and cost effectiveness of health facility and community based directly observed treatment of tuberculosis in an urban setting in Tanzania. Methods Two alternative strategies were compared: health facility based directly observed treatment by health personnel and community based directly observed treatment by treatment supervisors. Costs were analysed from the perspective of health services, patients and community in the year 2002 in US $ using standard methods. Treatment outcomes were obtained from a randomised-controlled trial which was conducted alongside the cost study. Smear positive, smear negative and extra-pulmonary TB patients were included. Cost-effectiveness was calculated as the cost per patient successfully treated. Results The total cost of treating a patient with conventional health facility based DOT and community based DOT were $ 145 and $ 94 respectively. Community based DOT reduced cost by 35%. Cost fell by 27% for health services and 72% for patients. When smear positive and smear negative patients were considered separately, community DOT was associated with 45% and 19% reduction of the costs respectively. Patients used about $ 43 to follow their medication to health facility which is equivalent to their monthly income. Indirect costs were as important as direct costs, contributing to about 49% of the total patient's cost. The main reason for reduced cost was fewer number of visits to the TB clinic. Community based DOT was more cost-effective at $ 128 per patient successfully treated compared to $ 203 for a patient successfully treated with health facility based DOT. Conclusion Community based DOT presents an economically attractive option to complement health facility based DOT. This is particularly important in settings where TB clinics are working beyond capacity under limited resources. PMID:16018806

  9. 32 CFR 766.4 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to land at a facility, provided such aircraft is not engaging in air commerce, and such landing is... to base or operate from a facility for personal convenience nor base at a facility under the guise of... engaging in air commerce, and such landing is for official business required by written orders. Such...

  10. The Effectiveness and Need for Facility Based Nurse Aide Training Competency Evaluation Programs.

    PubMed

    Mileski, Michael; McIlwain, Amber S; Kruse, Clemens Scott; Lieneck, Cristian; Sokan, Amanda

    2016-01-01

    It has become crucial for nursing facilities to rapidly train future nurse aides and remove any barriers to their matriculation into the field of care. Facilities feel the organizational burden of insufficient staffing and need to lever all effective programs to train future employees. The facility-based, Nurse Aide Training Competency Evaluation Programs (NATCEP) serve as a viable option to help fill shortages in the professional medical workforce. Data were analyzed from the National Nursing Assistant Survey to provide an overview of the benefits of using facility-trained nurse aides, versus those trained elsewhere, including their own perceptions of training and abilities. These findings also show the importance of facility based training programs for nurse aides on a global level. Providing training on site increases the efficiency and proficiency of nurse aides, making the transition to caregivers an easier for students, employers and residents.

  11. Downgrading Nuclear Facilities to Radiological Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jarry, Jeffrey F.; Farr, Jesse Oscar; Duran, Leroy

    2015-08-01

    Based on inventory reductions and the use of alternate storage facilities, the Sandia National Laboratories (SNL) downgraded 4 SNL Hazard Category 3 (HC-3) nuclear facilities to less-than-HC-3 radiological facilities. SNL’s Waste Management and Pollution Prevention Department (WMPPD) managed the HC-3 nuclear facilities and implemented the downgrade. This paper will examine the downgrade process,

  12. Facility-Level Characteristics Associated with Serious Suicide Attempts and Deaths from Suicide in Juvenile Justice Residential Facilities

    ERIC Educational Resources Information Center

    Gallagher, Catherine A.; Dobrin, Adam

    2006-01-01

    Little is known about how facility-level characteristics affect the risk of suicide and suicide attempts in juvenile justice residential facilities. This leaves facility administrators and mental health providers without evidence-based guidance on how the facility itself affects risks. The current study uses data from two recently developed…

  13. Coal gasification systems engineering and analysis. Appendix C: Alternate product facility designs

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The study of the production of methane, methanol, gasoline, and hydrogen by an add-on facility to a Koppers-Totzek based MBG plant is presented. Applications to a Texaco facility are inferred by evaluation of delta effects from the K-T cases. The production of methane from an add-on facility to a Lurgi based MBG plant and the co-production of methane and methanol from a Lurgi based system is studied. Studies are included of the production of methane from up to 50 percent of the MBG produced in an integrated K-T based plant and the production of methane from up to 50 percent of the MBG produced from an integrated plant in which module 1 is based on K-T technology and modules 2, 3, and 4 are based on Texaco technology.

  14. Environmental Assessment for Developing Renewable Energy Enhanced Use Lease Facilities at Robins Air Force Base

    DTIC Science & Technology

    2013-12-15

    Blufftown is underlain by igneous and metamorphic rocks which are equivalent to those of the Georgia Piedmont. Potable and process waters are produced...Final Environmental Assessment for Developing Renewable Energy Enhanced Use Lease Facilities at Robins Air Force Base...TITLE AND SUBTITLE Final Environmental Assessment for Developing Renewable Energy Enhanced Use Lease Facilities at Robins Air Force Base 5a. CONTRACT

  15. Environmental Assessment for Developing Renewable Energy Enhanced Use Lease Facilities at Robins Air Force Base

    DTIC Science & Technology

    2013-12-15

    underlain by igneous and metamorphic rocks which are equivalent to those of the Georgia Piedmont. Potable and process waters are produced from the...Final Environmental Assessment for Developing Renewable Energy Enhanced Use Lease Facilities at Robins Air Force Base...RENEWABLE ENERGY ENHANCED USE LEASE FACILITIES AT ROBINS AIR FORCE BASE In accordance with the National Environmental Policy Act (NEPA) of 1969 (42 U.S

  16. Environmental Assessment: Proposed Training Facilities, Hill Air Force Base, Utah

    DTIC Science & Technology

    2013-08-08

    FA8201-09-D-0002 Facilities, Hill Air Force Base, Utah 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Klein, Randal 5d...PERFORMING ORGANIZATION REPORT NUMBER Streamline Consulting, LLC 1713 N. Sweetwater Lane Farmington, Utah 84025...proposes to construct new training facilities at Hill Air Force Base, Utah . The findings of this EA indicate that the proposed action would not have

  17. View of Facility 222 (on right) and Facility 221 through ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Facility 222 (on right) and Facility 221 through trees (parapet of latter above trees) from the parade ground. - U.S. Naval Base, Pearl Harbor, Gymnasium & Theater, Neville Way, Pearl City, Honolulu County, HI

  18. Automated on-line renewable solid-phase extraction-liquid chromatography exploiting multisyringe flow injection-bead injection lab-on-valve analysis.

    PubMed

    Quintana, José Benito; Miró, Manuel; Estela, José Manuel; Cerdà, Víctor

    2006-04-15

    In this paper, the third generation of flow injection analysis, also named the lab-on-valve (LOV) approach, is proposed for the first time as a front end to high-performance liquid chromatography (HPLC) for on-line solid-phase extraction (SPE) sample processing by exploiting the bead injection (BI) concept. The proposed microanalytical system based on discontinuous programmable flow features automated packing (and withdrawal after single use) of a small amount of sorbent (<5 mg) into the microconduits of the flow network and quantitative elution of sorbed species into a narrow band (150 microL of 95% MeOH). The hyphenation of multisyringe flow injection analysis (MSFIA) with BI-LOV prior to HPLC analysis is utilized for on-line postextraction treatment to ensure chemical compatibility between the eluate medium and the initial HPLC gradient conditions. This circumvents the band-broadening effect commonly observed in conventional on-line SPE-based sample processors due to the low eluting strength of the mobile phase. The potential of the novel MSFI-BI-LOV hyphenation for on-line handling of complex environmental and biological samples prior to reversed-phase chromatographic separations was assessed for the expeditious determination of five acidic pharmaceutical residues (viz., ketoprofen, naproxen, bezafibrate, diclofenac, and ibuprofen) and one metabolite (viz., salicylic acid) in surface water, urban wastewater, and urine. To this end, the copolymeric divinylbenzene-co-n-vinylpyrrolidone beads (Oasis HLB) were utilized as renewable sorptive entities in the micromachined unit. The automated analytical method features relative recovery percentages of >88%, limits of detection within the range 0.02-0.67 ng mL(-1), and coefficients of variation <11% for the column renewable mode and gives rise to a drastic reduction in operation costs ( approximately 25-fold) as compared to on-line column switching systems.

  19. Final Environmental Assessment: Base-Wide Building Demolition Arnold Air Force Base, Tennessee

    DTIC Science & Technology

    2006-02-01

    Building • Engine Test Facility ( ETF )-B Exhauster • ETF -A Airside • ETF -A Exhauster • ETF -A Reefer • CE Facility • Rocket Storage • Von Karman Gas...Executive Order ESA Endangered Species Act ETF Engine Test Facility FamCamp Family Camping Area P:\\ARNOLDAFB\\333402DO42COMPLIANCE\\DEMOLITION...Fabrication Shop • Natural Resources Building • Salt Storage Building • Administration Building • Engine Test Facility ( ETF )-B Exhauster • ETF -A

  20. Capabilities and constraints of NASA's ground-based reduced gravity facilities

    NASA Technical Reports Server (NTRS)

    Lekan, Jack; Neumann, Eric S.; Sotos, Raymond G.

    1993-01-01

    The ground-based reduced gravity facilities of NASA have been utilized to support numerous investigations addressing various processes and phenomina in several disciplines for the past 30 years. These facilities, which include drop towers, drop tubes, aircraft, and sounding rockets are able to provide a low gravity environment (gravitational levels that range from 10(exp -2)g to 10(exp -6)g) by creating a free fall or semi-free fall condition where the force of gravity on an experiment is offset by its linear acceleration during the 'fall' (drop or parabola). The low gravity condition obtained on the ground is the same as that of an orbiting spacecraft which is in a state of perpetual free fall. The gravitational levels and associated duration times associated with the full spectrum of reduced gravity facilities including spaced-based facilities are summarized. Even though ground-based facilities offer a relatively short experiment time, this available test time has been found to be sufficient to advance the scientific understanding of many phenomena and to provide meaningful hardware tests during the flight experiment development process. Also, since experiments can be quickly repeated in these facilities, multistep phenomena that have longer characteristic times associated with them can sometimes be examined in a step-by-step process. There is a large body of literature which has reported the study results achieved through using reduced-gravity data obtained from the facilities.

  1. Simplifying ART cohort monitoring: can pharmacy stocks provide accurate estimates of patients retained on antiretroviral therapy in Malawi?

    PubMed

    Tweya, Hannock; Feldacker, Caryl; Ben-Smith, Anne; Harries, Anthony D; Komatsu, Ryuichi; Jahn, Andreas; Phiri, Sam; Tassie, Jean-Michel

    2012-07-20

    Routine monitoring of patients on antiretroviral therapy (ART) is crucial for measuring program success and accurate drug forecasting. However, compiling data from patient registers to measure retention in ART is labour-intensive. To address this challenge, we conducted a pilot study in Malawi to assess whether patient ART retention could be determined using pharmacy records as compared to estimates of retention based on standardized paper- or electronic based cohort reports. Twelve ART facilities were included in the study: six used paper-based registers and six used electronic data systems. One ART facility implemented an electronic data system in quarter three and was included as a paper-based system facility in quarter two only. Routine patient retention cohort reports, paper or electronic, were collected from facilities for both quarter two [April-June] and quarter three [July-September], 2010. Pharmacy stock data were also collected from the 12 ART facilities over the same period. Numbers of ART continuation bottles recorded on pharmacy stock cards at the beginning and end of each quarter were documented. These pharmacy data were used to calculate the total bottles dispensed to patients in each quarter with intent to estimate the number of patients retained on ART. Information for time required to determine ART retention was gathered through interviews with clinicians tasked with compiling the data. Among ART clinics with paper-based systems, three of six facilities in quarter two and four of five facilities in quarter three had similar numbers of patients retained on ART comparing cohort reports to pharmacy stock records. In ART clinics with electronic systems, five of six facilities in quarter two and five of seven facilities in quarter three had similar numbers of patients retained on ART when comparing retention numbers from electronically generated cohort reports to pharmacy stock records. Among paper-based facilities, an average of 13 4 hours was needed to calculate patient retention for cohort reporting using patient registers as compared to 2.25 hours using pharmacy stock cards. The numbers of patients retained on ART as estimated using pharmacy stock records were largely similar to estimates based on either paper registers or electronic data system. Furthermore, less time and staff effort was needed to estimate ART patient retention using pharmacy stock records versus paper-based registers. Reinforcing ARV stock management may improve the precision of estimates.

  2. 75 FR 9451 - Notice of Receipt and Availability of Environmental Report Supplement 2 for the Proposed GE...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... Availability of Environmental Report Supplement 2 for the Proposed GE-Hitachi Global Laser Enrichment Laser- Based Uranium Enrichment Facility On January 13, 2009, GE-Hitachi Global Laser Enrichment, LLC (GLE) was..., operation, and decommissioning of a laser-based uranium enrichment facility. The proposed facility would be...

  3. Information security management system planning for CBRN facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lenaeu, Joseph D.; O'Neil, Lori Ross; Leitch, Rosalyn M.

    The focus of this document is to provide guidance for the development of information security management system planning documents at chemical, biological, radiological, or nuclear (CBRN) facilities. It describes a risk-based approach for planning information security programs based on the sensitivity of the data developed, processed, communicated, and stored on facility information systems.

  4. 77 FR 29620 - Notice of Availability of Record of Decision for TRIDENT Support Facilities Explosives Handling...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... TRIDENT Support Facilities Explosives Handling Wharf at Naval Base Kitsap at Bangor, Kitsap County, WA... existing Explosives Handling Wharf in Hood Canal on the waterfront of Naval Base Kitsap (NBK) at Bangor, WA... Stevenson, Naval Facilities Engineering Command Northwest, 1101 Tautog Circle, Silverdale, WA 98315-1101...

  5. FACILITY 316. EXTERIOR OBLIQUE OF FRONT AS SEEN FROM FACILITY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 316. EXTERIOR OBLIQUE OF FRONT AS SEEN FROM FACILITY 362. VIEW FACING SOUTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

  6. Activity-based costing of health-care delivery, Haiti.

    PubMed

    McBain, Ryan K; Jerome, Gregory; Leandre, Fernet; Browning, Micaela; Warsh, Jonathan; Shah, Mahek; Mistry, Bipin; Faure, Peterson Abnis I; Pierre, Claire; Fang, Anna P; Mugunga, Jean Claude; Gottlieb, Gary; Rhatigan, Joseph; Kaplan, Robert

    2018-01-01

    To evaluate the implementation of a time-driven activity-based costing analysis at five community health facilities in Haiti. Together with stakeholders, the project team decided that health-care providers should enter start and end times of the patient encounter in every fifth patient's medical dossier. We trained one data collector per facility, who manually entered the time recordings and patient characteristics in a database and submitted the data to a cloud-based data warehouse each week. We calculated the capacity cost per minute for each resource used. An automated web-based platform multiplied reported time with capacity cost rate and provided the information to health-facilities administrators. Between March 2014 and June 2015, the project tracked the clinical services for 7162 outpatients. The cost of care for specific conditions varied widely across the five facilities, due to heterogeneity in staffing and resources. For example, the average cost of a first antenatal-care visit ranged from 6.87 United States dollars (US$) at a low-level facility to US$ 25.06 at a high-level facility. Within facilities, we observed similarly variation in costs, due to factors such as patient comorbidities, patient arrival time, stocking of supplies at facilities and type of visit. Time-driven activity-based costing can be implemented in low-resource settings to guide resource allocation decisions. However, the extent to which this information will drive observable changes at patient, provider and institutional levels depends on several contextual factors, including budget constraints, management, policies and the political economy in which the health system is situated.

  7. Activity-based costing of health-care delivery, Haiti

    PubMed Central

    Jerome, Gregory; Leandre, Fernet; Browning, Micaela; Warsh, Jonathan; Shah, Mahek; Mistry, Bipin; Faure, Peterson Abnis I; Pierre, Claire; Fang, Anna P; Mugunga, Jean Claude; Gottlieb, Gary; Rhatigan, Joseph; Kaplan, Robert

    2018-01-01

    Abstract Objective To evaluate the implementation of a time-driven activity-based costing analysis at five community health facilities in Haiti. Methods Together with stakeholders, the project team decided that health-care providers should enter start and end times of the patient encounter in every fifth patient’s medical dossier. We trained one data collector per facility, who manually entered the time recordings and patient characteristics in a database and submitted the data to a cloud-based data warehouse each week. We calculated the capacity cost per minute for each resource used. An automated web-based platform multiplied reported time with capacity cost rate and provided the information to health-facilities administrators. Findings Between March 2014 and June 2015, the project tracked the clinical services for 7162 outpatients. The cost of care for specific conditions varied widely across the five facilities, due to heterogeneity in staffing and resources. For example, the average cost of a first antenatal-care visit ranged from 6.87 United States dollars (US$) at a low-level facility to US$ 25.06 at a high-level facility. Within facilities, we observed similarly variation in costs, due to factors such as patient comorbidities, patient arrival time, stocking of supplies at facilities and type of visit. Conclusion Time-driven activity-based costing can be implemented in low-resource settings to guide resource allocation decisions. However, the extent to which this information will drive observable changes at patient, provider and institutional levels depends on several contextual factors, including budget constraints, management, policies and the political economy in which the health system is situated. PMID:29403096

  8. Does a voucher program improve reproductive health service delivery and access in Kenya?

    PubMed

    Njuki, Rebecca; Abuya, Timothy; Kimani, James; Kanya, Lucy; Korongo, Allan; Mukanya, Collins; Bracke, Piet; Bellows, Ben; Warren, Charlotte E

    2015-05-23

    Current assessments on Output-Based Aid (OBA) programs have paid limited attention to the experiences and perceptions of the healthcare providers and facility managers. This study examines the knowledge, attitudes, and experiences of healthcare providers and facility managers in the Kenya reproductive health output-based approach voucher program. A total of 69 in-depth interviews with healthcare providers and facility managers in 30 voucher accredited facilities were conducted. The study hypothesized that a voucher program would be associated with improvements in reproductive health service provision. Data were transcribed and analyzed by adopting a thematic framework analysis approach. A combination of inductive and deductive analysis was conducted based on previous research and project documents. Facility managers and providers viewed the RH-OBA program as a feasible system for increasing service utilization and improving quality of care. Perceived benefits of the program included stimulation of competition between facilities and capital investment in most facilities. Awareness of family planning (FP) and gender-based violence (GBV) recovery services voucher, however, remained lower than the maternal health voucher service. Relations between the voucher management agency and accredited facilities as well as existing health systems challenges affect program functions. Public and private sector healthcare providers and facility managers perceive value in the voucher program as a healthcare financing model. They recognize that it has the potential to significantly increase demand for reproductive health services, improve quality of care and reduce inequities in the use of reproductive health services. To improve program functioning going forward, there is need to ensure the benefit package and criteria for beneficiary identification are well understood and that the public facilities are permitted greater autonomy to utilize revenue generated from the voucher program.

  9. A method for studying the development pattern of urban commercial service facilities based on customer reviews from social media

    NASA Astrophysics Data System (ADS)

    Wang, Y. D.; Jiang, B. T.; Ye, X. Y.

    2016-06-01

    Urbanization is one of the most important human social activities in the 21st century (Chaolin et al., 2012). With an increasing number of people visiting cities, the provision of adequate urban service facilities, including public and commercial service facilities, in locations where people live has become an important guarantee of the success of urbanization. Exploring the commercial service facilities in a specific area of a city can help us understand the progress and trends of urban renewal in the area, provide a quantitative basis for evaluating the rationality of planning implementation, and facilitate an analysis of the effects of different factors on the regional development of a city (Schor et al. 2003). In this paper, we proposed a data processing and analysis method for studying the distribution and development pattern of urban commercial facilities based on customer reviews. In addition, based on road network constraints, we explored the patterns contained in customer reviews data, including patterns for the spatial distribution and spatial-temporal evolution of facilities as well as the number of facilities and degree of satisfaction.

  10. Facilities Performance Indicators Report 2011-12: Tracking Your Facilities Vital Signs

    ERIC Educational Resources Information Center

    APPA: Association of Higher Education Facilities Officers, 2013

    2013-01-01

    This paper provides an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. APPA's Information and Research Committee's goal for this year was to enhance the…

  11. 77 FR 31841 - Notice of Applications for Authorization To Abandon Facilities and Services and To Acquire...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... To Abandon Facilities and Services and To Acquire Facilities by Merger Steuben Gas Storage Company... Field Storage Facilities (Adrian Field) which Steuben operates pursuant to certificates of public... authorization to charge market based rates following its acquisition of the Adrian Field Storage Facility. The...

  12. Design of carbon therapy facility based on 10 years experience at HIMAC

    NASA Astrophysics Data System (ADS)

    Noda, K.; Furukawa, T.; Iwata, Y.; Kanai, T.; Kanazawa, M.; Kanematsu, N.; Kitagawa, A.; Komori, M.; Minohara, S.; Murakami, T.; Muramatsu, M.; Sato, S.; Sato, Y.; Shibuya, S.; Torikoshi, M.; Yamada, S.

    2006-06-01

    Since 1994, the clinical trial for cancer therapy with HIMAC has successfully progressed, and more than 2100 cancer patients have been treated with a carbon beam. Based on the development of the accelerator and irradiation technologies for 10 years, we have designed a new carbon-therapy facility for widespread use in Japan, and key technologies for the new facility have been developed. We describe the conceptual design of the new facility and the status of development for the key technologies.

  13. Human Research Initiative (HRI)

    NASA Technical Reports Server (NTRS)

    Motil, Brian

    2003-01-01

    A code U initiative starting in the FY04 budget includes specific funding for 'Phase Change' and 'Multiphase Flow Research' on the ISS. NASA GRC developed a concept for two facilities based on funding/schedule constraints: 1) Two Phase Flow Facility (TphiFFy) which assumes integrating into FIR; 2) Contact Line Dynamics Experiment Facility (CLiDE) which assumes integration into MSG. Each facility will accommodate multiple experiments conducted by NRA selected PIs with an overall goal of enabling specific NASA strategic objectives. There may also be a significant ground-based component.

  14. Increase in facility-based deliveries associated with a maternal health voucher programme in informal settlements in Nairobi, Kenya.

    PubMed

    Bellows, Ben; Kyobutungi, Catherine; Mutua, Martin Kavao; Warren, Charlotte; Ezeh, Alex

    2013-03-01

    To measure whether there was an association between the introduction of an output-based voucher programme and the odds of a facility-based delivery in two Nairobi informal settlements. Nairobi Urban Health and Demographic Surveillance System (NUHDSS) and two cross-sectional household surveys in Korogocho and Viwandani informal settlements in 2004-05 and 2006-08. Odds of facility-based delivery were estimated before and after introduction of an output-based voucher. Supporting NUHDSS data were used to determine whether any trend in maternal health care was coincident with immunizations, a non-voucher outpatient service. As part of NUHDSS, households in Korogocho and Viwandani reported place of delivery and the presence of a skilled birth attendant (2003-10) and vaccination coverage (2003-09). A detailed maternal and child health (MCH) tool was added to NUHDSS (September 2006-10). Prospective enrolment in NUHDSS-MCH was conditional on having a newborn after September 2006. In addition to recording mother's place of delivery, NUHDSS-MCH recorded the use of the voucher. There were significantly greater odds of a facility-based delivery among respondents during the voucher programme compared with similar respondents prior to voucher launch. Testing whether unrelated outpatient care also increased, a falsification exercise found no significant increase in immunizations for children 12-23 months of age in the same period. Although the proportion completing any antenatal care (ANC) visit remained above 95% of all reported pregnancies and there was a significant increase in facility-based deliveries, the proportion of women completing 4+ ANC visits was significantly lower during the voucher programme. A positive association was observed between vouchers and facility-based deliveries in Nairobi. Although there is a need for higher quality evidence and validation in future studies, this statistically significant and policy relevant finding suggests that increases in facility-based deliveries can be achieved through output-based finance models that target subsidies to underserved populations.

  15. FACILITY 317. EXTERIOR OF FRONT SIDE, WITH FACILITY 316 BEYOND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 317. EXTERIOR OF FRONT SIDE, WITH FACILITY 316 BEYOND ON THE LEFT. VIEW FACING NORTH. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hospital Point, Pharmacist's Quarters Type, 13-16 First Street, Pearl City, Honolulu County, HI

  16. Using health-facility data to assess subnational coverage of maternal and child health indicators, Kenya.

    PubMed

    Maina, Isabella; Wanjala, Pepela; Soti, David; Kipruto, Hillary; Droti, Benson; Boerma, Ties

    2017-10-01

    To develop a systematic approach to obtain the best possible national and subnational statistics for maternal and child health coverage indicators from routine health-facility data. Our approach aimed to obtain improved numerators and denominators for calculating coverage at the subnational level from health-facility data. This involved assessing data quality and determining adjustment factors for incomplete reporting by facilities, then estimating local target populations based on interventions with near-universal coverage (first antenatal visit and first dose of pentavalent vaccine). We applied the method to Kenya at the county level, where routine electronic reporting by facilities is in place via the district health information software system. Reporting completeness for facility data were well above 80% in all 47 counties and the consistency of data over time was good. Coverage of the first dose of pentavalent vaccine, adjusted for facility reporting completeness, was used to obtain estimates of the county target populations for maternal and child health indicators. The country and national statistics for the four-year period 2012/13 to 2015/16 showed good consistency with results of the 2014 Kenya demographic and health survey. Our results indicated a stagnation of immunization coverage in almost all counties, a rapid increase of facility-based deliveries and caesarean sections and limited progress in antenatal care coverage. While surveys will continue to be necessary to provide population-based data, web-based information systems for health facility reporting provide an opportunity for more frequent, local monitoring of progress, in maternal and child health.

  17. Rayleigh Scattering for Measuring Flow in a Nozzle Testing Facility

    NASA Technical Reports Server (NTRS)

    Gomez, Carlos R.; Panda, Jayanta

    2006-01-01

    A molecular Rayleigh-scattering-based air-density measurement system was built in a large nozzle-and-engine-component test facility for surveying supersonic plumes from jet-engine exhaust. A molecular Rayleigh-scattering-based air-density measurement system was built in a large nozzle-and-enginecomponent test facility for surveying supersonic plumes from jet-engine exhaust

  18. Facility Composer (Trademark) and PACES (Trademark) Integration: Development of an XML Interface Based on Industry Foundation Classes

    DTIC Science & Technology

    2007-11-01

    Engineer- ing Research Laboratory is currently developing a set of facility ‘architec- tural’ programming tools , called Facility ComposerTM (FC). FC...requirements in the early phases of project development. As the facility program, crite- ria, and requirements are chosen, these tools populate the IFC...developing a set of facility “ar- chitectural” programming tools , called Facility Composer (FC), to support the capture and tracking of facility criteria

  19. The Alto Tandem and Isol Facility at IPN Orsay

    NASA Astrophysics Data System (ADS)

    Franchoo, Serge

    Alto is an infrastructure for experimental nuclear physics in France that comprises both an on-line isotope-separation facility based on the photofission of uranium and a stable-ion beam facility based on a 14.5-MV tandem accelerator. The isotope-separation on-line section of Alto is dedicated to the production of neutron-rich radioactive ion beams (RIB) from the interaction of the γ-flux induced by a 50-MeV 10-µA electron beam in a uranium-carbide target. It is dimensioned for 1011 fissions per second. The RIB facility is exploited in alternating mode with the tandem-based section of Alto, capable of accelerating both light ions for nuclear astrophysics and heavy ions for γ-spectroscopy. The facility thereby offers the opportunity to deliver beams to a large range of physics programmes from nuclear to interdisciplinary physics. In this article, we present the Alto facility as well as some of the highlights and prospects of the experimental programme.

  20. Case-Mix Adjusting Performance Measures in a Veteran Population: Pharmacy- and Diagnosis-Based Approaches

    PubMed Central

    Liu, Chuan-Fen; Sales, Anne E; Sharp, Nancy D; Fishman, Paul; Sloan, Kevin L; Todd-Stenberg, Jeff; Nichol, W Paul; Rosen, Amy K; Loveland, Susan

    2003-01-01

    Objective To compare the rankings for health care utilization performance measures at the facility level in a Veterans Health Administration (VHA) health care delivery network using pharmacy- and diagnosis-based case-mix adjustment measures. Data Sources/Study Setting The study included veterans who used inpatient or outpatient services in Veterans Integrated Service Network (VISN) 20 during fiscal year 1998 (October 1997 to September 1998; N=126,076). Utilization and pharmacy data were extracted from VHA national databases and the VISN 20 data warehouse. Study Design We estimated concurrent regression models using pharmacy or diagnosis information in the base year (FY1998) to predict health service utilization in the same year. Utilization measures included bed days of care for inpatient care and provider visits for outpatient care. Principal Findings Rankings of predicted utilization measures across facilities vary by case-mix adjustment measure. There is greater consistency within the diagnosis-based models than between the diagnosis- and pharmacy-based models. The eight facilities were ranked differently by the diagnosis- and pharmacy-based models. Conclusions Choice of case-mix adjustment measure affects rankings of facilities on performance measures, raising concerns about the validity of profiling practices. Differences in rankings may reflect differences in comparability of data capture across facilities between pharmacy and diagnosis data sources, and unstable estimates due to small numbers of patients in a facility. PMID:14596393

  1. Short-term effect of zoledronic acid upon fracture resistance of the mandibular condyle and femoral head in an animal model.

    PubMed

    Camacho-Alonso, Fabio; López-Jornet, Pía; Vicente-Hernández, Ascensión

    2013-05-01

    The aim of this study was to compare the effects in terms of resistance to fracture of the mandibular condyle and femoral head following different doses of zoledronic acid in an animal model. A total of 80 adult male Sprague-Dawley rats were included in a prospective randomized study. The animals were randomly divided into four groups of 20 rats each. Group 1 (control) received sterile saline solution, while groups 2, 3 and 4 received a accumulated dose of 0.2 mg, 0.4 mg and 0.6 mg of zoledronic acid, respectively. The animals were sacrificed 28 days after the last dose, and the right hemimandible and the right femur were removed. The fracture strength was measured (in Newtons) with a universal test machine using a 1 kN load connected to a metal rod with one end angled at 30 degrees. The cross-head speed was 1 mm/min. Later, the specimens were observed under a scanning electron microscope with backscattered electron imaging (SEM-BSE). At last, chemical analysis and elemental mapping of the mineral bone composition were generated using a microanalytical system based on energy-dispersive and X-ray spectrometry (EDX). A total of 160 fracture tests were performed. The fracture resistance increased in mandible and femur with a higher accumulated dose of zoledronic acid. Statistically significant differences were recorded versus the controls with all the studies groups. The chemical analysis in mandible showed a significantly increased of calcium and phosphorous to compare the control with all of the study groups; however, in femur no statistically significant differences between the four study groups were observed. The administration of bisphosphonates increases the fracture resistance in mandible and femur.

  2. Blending Curriculum with Research in an Undergraduate Petrology Course: A Recipe for Success?

    NASA Astrophysics Data System (ADS)

    Gonzales, D. A.; Semken, S. C.

    2009-12-01

    In this presentation we discuss the design, key curricular elements, and strengths and weaknesses of an undergraduate course in the Department of Geosciences at Fort Lewis College that was recast to focus on petrologic studies in the Southern Rocky Mountains and Colorado Plateau. Redesign of the course retained an additional petrology option in the curriculum and offered undergraduates a richer opportunity to learn and practice science-research skills. This course emphasizes direct engagement and student responsibility for learning: traits valuable in transforming undergraduates into experienced and competent professionals. Previous offerings of this course have been field based, each having a unique context for research. The primary pedagogical strategy was to blend field studies with inquiry to promote authentic, student-driven research. Students applied and tested their prior knowledge, and used observational and interpretative skills, to investigate major regional rock bodies and geologic histories, as opposed to completing a set of activities with predefined outcomes. In 2010, students will work on an NSF-funded project to test hypotheses on the origin and evolution of mafic magmas of the Navajo volcanic field. This research will most involve petrographic and microanalytical techniques on rock specimens with a subordinate amount of field work. Formative and summative assessment data for previous offerings of this course reveal that these classes have an impact on the academic interests and future successes of students. Assessment data collected from students, and other faculty that interacted with them, indicate that students in this research-oriented petrology course have gained a greater understanding of the elements and complications of research. They have also developed geologic skills and a passion for geologic research that have influenced subsequent academic (and later career) paths of the students.

  3. A Generalized Approach to Forensic Dye Identification: Development and Utility of Reference Libraries.

    PubMed

    Groves, Ethan; Palenik, Skip; Palenik, Christopher S

    2018-04-18

    While color is arguably the most important optical property of evidential fibers, the actual dyestuffs responsible for its expression in them are, in forensic trace evidence examinations, rarely analyzed and still less often identified. This is due, primarily, to the exceedingly small quantities of dye present in a single fiber as well as to the fact that dye identification is a challenging analytical problem, even when large quantities are available for analysis. Among the practical reasons for this are the wide range of dyestuffs available (and the even larger number of trade names), the low total concentration of dyes in the finished product, the limited amount of sample typically available for analysis in forensic cases, and the complexity of the dye mixtures that may exist within a single fiber. Literature on the topic of dye analysis is often limited to a specific method, subset of dyestuffs, or an approach that is not applicable given the constraints of a forensic analysis. Here, we present a generalized approach to dye identification that ( 1 ) combines several robust analytical methods, ( 2 ) is broadly applicable to a wide range of dye chemistries, application classes, and fiber types, and ( 3 ) can be scaled down to forensic casework-sized samples. The approach is based on the development of a reference collection of 300 commercially relevant textile dyes that have been characterized by a variety of microanalytical methods (HPTLC, Raman microspectroscopy, infrared microspectroscopy, UV-Vis spectroscopy, and visible microspectrophotometry). Although there is no single approach that is applicable to all dyes on every type of fiber, a combination of these analytical methods has been applied using a reproducible approach that permits the use of reference libraries to constrain the identity of and, in many cases, identify the dye (or dyes) present in a textile fiber sample.

  4. The Analytical Limits of Modeling Short Diffusion Timescales

    NASA Astrophysics Data System (ADS)

    Bradshaw, R. W.; Kent, A. J.

    2016-12-01

    Chemical and isotopic zoning in minerals is widely used to constrain the timescales of magmatic processes such as magma mixing and crystal residence, etc. via diffusion modeling. Forward modeling of diffusion relies on fitting diffusion profiles to measured compositional gradients. However, an individual measurement is essentially an average composition for a segment of the gradient defined by the spatial resolution of the analysis. Thus there is the potential for the analytical spatial resolution to limit the timescales that can be determined for an element of given diffusivity, particularly where the scale of the gradient approaches that of the measurement. Here we use a probabilistic modeling approach to investigate the effect of analytical spatial resolution on estimated timescales from diffusion modeling. Our method investigates how accurately the age of a synthetic diffusion profile can be obtained by modeling an "unknown" profile derived from discrete sampling of the synthetic compositional gradient at a given spatial resolution. We also include the effects of analytical uncertainty and the position of measurements relative to the diffusion gradient. We apply this method to the spatial resolutions of common microanalytical techniques (LA-ICP-MS, SIMS, EMP, NanoSIMS). Our results confirm that for a given diffusivity, higher spatial resolution gives access to shorter timescales, and that each analytical spacing has a minimum timescale, below which it overestimates the timescale. For example, for Ba diffusion in plagioclase at 750 °C timescales are accurate (within 20%) above 10, 100, 2,600, and 71,000 years at 0.3, 1, 5, and 25 mm spatial resolution, respectively. For Sr diffusion in plagioclase at 750 °C, timescales are accurate above 0.02, 0.2, 4, and 120 years at the same spatial resolutions. Our results highlight the importance of selecting appropriate analytical techniques to estimate accurate diffusion-based timescales.

  5. Doing, talking and writing science: A discourse analysis of the process of resemiotization in a middle school lab-based science class

    NASA Astrophysics Data System (ADS)

    Wright, Laura J.

    This study examines students' sense making practices in a middle school science class from a discourse analytic perspective. Using Mediated Discourse Analysis (MDA) (Scollon 1998, 2001) and interactional sociolinguistics (Gumperz 1999, 2001, Schiffrin 1994), my research seeks to enrich findings from recent sociocultural studies of science classrooms that focus on doing, talking and writing science (Roth 2005, Kress, et al. 2002, Halliday & Martin 1993, Lemke 1990). Within a middle school science classroom, these fundamental activities form a nexus of practice (Scollon 1998, 2001) basic to science literacy (AAAS 1989) and reflective of the work of practicing scientists. Moreover, students' engagement in these practices provides insight into the cultural production and reproduction of science and scientist. I first examine how the students' curriculum text encourages these three scientific practices and then trace students' uptake; that is, how they subsequently do, talk, and write science throughout the course of the unit. I argue that learning science with this curriculum unit requires students to resemiotize (Iedema 2001, 2003) first hand experience so they can represent their knowledge cohesively and coherently in evaluable forms. Ultimately, students must transform language from the curriculum text and their teacher into action in their laboratory activities and action in their laboratory activities into language. In addition, I show how students are apprenticed to the conventionalized practices and voices (Bakhtin 1986) of science (i.e. the scientific register), and how their figures of personhood (Agha 2005) reflect the development of their scientific identities. Overall, I argue that the microanalytic methods I use illuminate how students draw upon curricular resources to become scientifically literate and develop scientific identities.

  6. Evaluation of laboratory powder X-ray micro-diffraction for applications in the fields of cultural heritage and forensic science.

    PubMed

    Svarcová, Silvie; Kocí, Eva; Bezdicka, Petr; Hradil, David; Hradilová, Janka

    2010-09-01

    The uniqueness and limited amounts of forensic samples and samples from objects of cultural heritage together with the complexity of their composition requires the application of a wide range of micro-analytical methods, which are non-destructive to the samples, because these must be preserved for potential late revision. Laboratory powder X-ray micro-diffraction (micro-XRD) is a very effective non-destructive technique for direct phase analysis of samples smaller than 1 mm containing crystal constituents. It compliments optical and electron microscopy with elemental micro-analysis, especially in cases of complicated mixtures containing phases with similar chemical composition. However, modification of X-ray diffraction to the micro-scale together with its application for very heterogeneous real samples leads to deviations from the standard procedure. Knowledge of both the limits and the phenomena which can arise during the analysis is crucial for the meaningful and proper application of the method. We evaluated basic limits of micro-XRD equipped with a mono-capillary with an exit diameter of 0.1 mm, for example the size of irradiated area, appropriate grain size, and detection limits allowing identification of given phases. We tested the reliability and accuracy of quantitative phase analysis based on micro-XRD data in comparison with conventional XRD (reflection and transmission), carrying out experiments with two-phase model mixtures simulating historic colour layers. Furthermore, we demonstrate the wide use of micro-XRD for investigation of various types of micro-samples (contact traces, powder traps, colour layers) and we show how to enhance data quality by proper choice of experiment geometry and conditions.

  7. The oxidation state of Fe in MORB glasses and the oxygen fugacity of the upper mantle

    NASA Astrophysics Data System (ADS)

    Cottrell, Elizabeth; Kelley, Katherine A.

    2011-05-01

    Micro-analytical determination of Fe3+/∑Fe ratios in mid-ocean ridge basalt (MORB) glasses using micro X-ray absorption near edge structure (μ-XANES) spectroscopy reveals a substantially more oxidized upper mantle than determined by previous studies. Here, we show that global MORBs yield average Fe3+/∑Fe ratios of 0.16 ± 0.01 (n = 103), which trace back to primary MORB melts equilibrated at the conditions of the quartz-fayalite-magnetite (QFM) buffer. Our results necessitate an upward revision of the Fe3+/∑Fe ratios of MORBs, mantle oxygen fugacity, and the ferric iron content of the mantle relative to previous wet chemical determinations. We show that only 0.01 (absolute, or < 10%) of the difference between Fe3+/∑Fe ratios determined by micro-colorimety and XANES can be attributed to the Mössbauer-based XANES calibration. The difference must instead derive from a bias between micro-colorimetry performed on experimental vs. natural basalts. Co-variations of Fe3+/∑Fe ratios in global MORB with indices of low-pressure fractional crystallization are consistent with Fe3+ behaving incompatibly in shallow MORB magma chambers. MORB Fe3+/∑Fe ratios do not, however, vary with indices of the extent of mantle melting (e.g., Na2O(8)) or water concentration. We offer two hypotheses to explain these observations: The bulk partition coefficient of Fe3+ may be higher during peridotite melting than previously thought, and may vary with temperature, or redox exchange between sulfide and sulfate species could buffer mantle melting at ~ QFM. Both explanations, in combination with the measured MORB Fe3+/∑Fe ratios, point to a fertile MORB source with greater than 0.3 wt.% Fe2O3.

  8. Laser micromachined isoelectric focusing devices on polymer substrate for electrospray mass spectrometry

    NASA Astrophysics Data System (ADS)

    Lin, Yuehe; Wen, Jenny; Fan, Xiang; Matson, Dean W.; Smith, Richard D.

    1999-08-01

    A microfabricated device for isoelectric focusing (IEF) incorporating an optimized electrospray ionization (ESI) tip was constructed on polycarbonate plates using a laser micromachining technique. The separation channels on an IEF chip were 16 cm long, 50 micrometers wide and 30 micrometers deep. Electrical potentials used for IEF focusing and electrospray were applied through platinum electrodes placed in the buffer reservoirs, and which were isolated from the separation channel by molecular porous membranes. On-line ESI produced directly from a sharp `tip' on the microchip was evaluated. The results indicate that this design can produce a stable electrospray that is further improved and made more flexible with the assistance of sheath gas and sheath liquid. Error analysis of the spectral data shows that the standard deviation in signal intensity for an analyte peak was less than approximately 5% over 3 hours. The production of stable electrosprays directly from microchip IEF devices represents a step towards easily- fabricated microanalytical devices. IEF separations of protein mixtures were demonstrated for uncoated polycarbonate microchips. On-line IEF/ESI-MS was demonstrated using the microfabricated chip with an ion-trap ESI mass spectrometer for characterization of protein mixtures.

  9. Gender Differences in Emotion Expression in Low-Income Adolescents Under Stress

    PubMed Central

    Panjwani, Naaila; Chaplin, Tara M.; Sinha, Rajita; Mayes, Linda C.

    2015-01-01

    Gender roles in mainstream U.S. culture suggest that girls express more happiness, sadness, anxiety, and shame/embarrassment than boys, while boys express more anger and externalizing emotions, such as contempt. However, gender roles and emotion expression may be different in low-income and ethnically diverse families, as children and parents are often faced with greater environmental stressors and may have different gender expectations. This study examined gender differences in emotion expression in low-income adolescents, an understudied population. One hundred and seventy nine adolescents (aged 14-17) participated in the Trier Social Stress Test (TSST). Trained coders rated adolescents’ expressions of happiness, sadness, anxiety, shame/embarrassment, anger, and contempt during the TSST using a micro-analytic coding system. Analyses showed that, consistent with gender roles, girls expressed higher levels of happiness and shame than boys; however, contrary to traditional gender roles, girls showed higher levels of contempt than boys. Also, in contrast to cultural stereotypes, there were no differences in anger between boys and girls. Findings suggest gender-role inconsistent displays of externalizing emotions in low-income adolescents under acute stress, and may reflect different emotion socialization experiences in this group. PMID:29056804

  10. Gender Differences in Emotion Expression in Low-Income Adolescents Under Stress.

    PubMed

    Panjwani, Naaila; Chaplin, Tara M; Sinha, Rajita; Mayes, Linda C

    2016-06-01

    Gender roles in mainstream U.S. culture suggest that girls express more happiness, sadness, anxiety, and shame/embarrassment than boys, while boys express more anger and externalizing emotions, such as contempt. However, gender roles and emotion expression may be different in low-income and ethnically diverse families, as children and parents are often faced with greater environmental stressors and may have different gender expectations. This study examined gender differences in emotion expression in low-income adolescents, an understudied population. One hundred and seventy nine adolescents (aged 14-17) participated in the Trier Social Stress Test (TSST). Trained coders rated adolescents' expressions of happiness, sadness, anxiety, shame/embarrassment, anger, and contempt during the TSST using a micro-analytic coding system. Analyses showed that, consistent with gender roles, girls expressed higher levels of happiness and shame than boys; however, contrary to traditional gender roles, girls showed higher levels of contempt than boys. Also, in contrast to cultural stereotypes, there were no differences in anger between boys and girls. Findings suggest gender-role inconsistent displays of externalizing emotions in low-income adolescents under acute stress, and may reflect different emotion socialization experiences in this group.

  11. Propellant's differentiation using FTIR-photoacoustic detection for forensic studies of improvised explosive devices.

    PubMed

    Álvarez, Ángela; Yáñez, Jorge; Contreras, David; Saavedra, Renato; Sáez, Pedro; Amarasiriwardena, Dulasiri

    2017-11-01

    The use of propellant for making improvised explosive devices (IED) is an incipient criminal practice. Propellant can be used as initiator in explosive mixtures along with other components such as coal, ammonium nitrate, sulfur, etc. The identification of the propellant's brand used in homemade explosives can provide additional forensic information of this evidence. In this work, four of the most common propellant brands were characterized by Fourier-transform infrared photoacoustic spectroscopy (FTIR-PAS) which is a non-destructive micro-analytical technique. Spectra shows characteristic signals of typical compounds in the propellants, such as nitrocellulose, nitroglycerin, guanidine, diphenylamine, etc. The differentiation of propellant components was achieved by using FTIR-PAS combined with chemometric methods of classification. Principal component analysis (PCA) and soft independent modelling of class analogy (SIMCA) were used to achieve an effective differentiation and classification (100%) of propellant brands. Furthermore, propellant brand differentiation was also assessed using partial least squares discriminant analyses (PLS-DA) by leave one out cross (∼97%) and external (∼100%) validation method. Our results show the ability of FTIR-PAS combined with chemometric analysis to identify and differentiate propellant brands in different explosive formulations of IED. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Stable isotopes in mid-ocean ridge hydrothermal systems: Interactions between fluids, minerals, and organisms

    USGS Publications Warehouse

    Shanks, Wayne C.; Böhlke, John Karl; Seal, Robert R.; Humphries, S.D.; Zierenberg, Robert A.; Mullineaux, Lauren S.; Thomson, Richard E.

    1995-01-01

    Studies of abundance variations of light stable isotopes in nature have had a tremendous impact on all aspects of geochemistry since the development, in 1947, of a gas source isotope ratio mass spectrometer capable of measuring small variations in stable isotope ratios (Nice, 1947]. Stable isotope geochemistry is now a mature field, as witnessed by the proliferation of commercially available mass spectrometers installed at virtually every major academic, government, and private-sector research geochemistry laboratory. A recent search of a literature database revealed over 3,000 articles that utilized stable isotope geochemistry over the last 20 years. Nonetheless, many exciting new technical developments are leading to exciting new discoveries and applications. In particular, micro-analytical techniques involving new generations of laser- and ion-microprobes are revolutionizing the types of analyses that can be done on spot sizes as small as a few tens of micrometers [Shanks and Criss, 1989]. New generations of conventional gas source and thermal ionization mass spectrometers, with high levels of automation and increased sensitivity and precision, are allowing analyses of large numbers of samples, like those needed for stable isotope stratigraphy in marine sediments, and are enabling the development and application of new isotopic systems.

  13. Analysis of metal-binding proteins separated by non-denaturating gel electrophoresis using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).

    PubMed

    Becker, J Susanne; Mounicou, Sandra; Zoriy, Miroslav V; Becker, J Sabine; Lobinski, Ryszard

    2008-09-15

    Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) have become established as very efficient and sensitive biopolymer and elemental mass spectrometric techniques for studying metal-binding proteins (metalloproteins) in life sciences. Protein complexes present in rat tissues (liver and kidney) were separated in their native state in the first dimension by blue native gel electrophoresis (BN-PAGE). Essential and toxic metals, such as zinc, copper, iron, nickel, chromium, cadmium and lead, were detected by scanning the gel bands using quadrupole LA-ICP-MS with and without collision cell as a microanalytical technique. Several proteins were identified by using MALDI-TOF-MS together with a database search. For example, on one protein band cut from the BN-PAGE gel and digested with the enzyme trypsin, two different proteins - protein FAM44B and cathepsin B precursor - were identified. By combining biomolecular and elemental mass spectrometry, it was possible to characterize and identify selected metal-binding rat liver and kidney tissue proteins.

  14. Integration of electrochemistry in micro-total analysis systems for biochemical assays: recent developments.

    PubMed

    Xu, Xiaoli; Zhang, Song; Chen, Hui; Kong, Jilie

    2009-11-15

    Micro-total analysis systems (microTAS) integrate different analytical operations like sample preparation, separation and detection into a single microfabricated device. With the outstanding advantages of low cost, satisfactory analytical efficiency and flexibility in design, highly integrated and miniaturized devices from the concept of microTAS have gained widespread applications, especially in biochemical assays. Electrochemistry is shown to be quite compatible with microanalytical systems for biochemical assays, because of its attractive merits such as simplicity, rapidity, high sensitivity, reduced power consumption, and sample/reagent economy. This review presents recent developments in the integration of electrochemistry in microdevices for biochemical assays. Ingenious microelectrode design and fabrication methods, and versatility of electrochemical techniques are involved. Practical applications of such integrated microsystem in biochemical assays are focused on in situ analysis, point-of-care testing and portable devices. Electrochemical techniques are apparently suited to microsystems, since easy microfabrication of electrochemical elements and a high degree of integration with multi-analytical functions can be achieved at low cost. Such integrated microsystems will play an increasingly important role for analysis of small volume biochemical samples. Work is in progress toward new microdevice design and applications.

  15. Subcellular distribution of a new fluorinated, biocompatible, non-ionic telomeric carrier: a study in cultured B16 melanoma and rat skin fibroblasts.

    PubMed

    Chehade, F; Maurizis, J C; Pucci, B; Pavia, A A; Ollier, M; Veyre, A; Escaig, F; Jeanguillaume, C; Dennebouy, R; Slodzian, G; Hindié, E

    1996-05-01

    Tris-hydroxymethyl-amino-methane telomers bearing a fluorinated end have recently been proposed as potential drug carriers. Using ion microscopy, we have investigated the cell uptake and subcellular distribution of a perfluorinated telomere, called F-TAC, in two cell lines, malignant murine B16 melanoma and normal rat skin fibroblasts. Single layer cell cultures on gold plates were incubated with F-TAC at different concentrations. Ion microscopy using mass spectrometry enabled the detection of Fluorine 19 atoms entering into F-TAC constitution. This microanalytical study showed an elective cytoplasmic localization of the molecule, wherein the distribution is relatively homogeneous. Within same culture and incubation conditions, intercellular variations in F-TAC content were very low. In the malignant line, the intracellular concentration remains practically identical when increasing F-TAC concentration in the culture medium above 0.2 mg/ml, indicating that the uptake phenomenon is saturable. In conclusion, the F-TAC telomer easily crosses the plasma membrane, however, it has difficulties in crossing the nuclear membrane. It is likely that intracellular penetration is essentially due to rapid endocytosis of the telomer.

  16. Facility and market factors affecting transitions from nursing home to community.

    PubMed

    Arling, Greg; Abrahamson, Kathleen A; Cooke, Valerie; Kane, Robert L; Lewis, Teresa

    2011-09-01

    Research into nursing home transitions has given limited attention to the facility or community contexts. To identify facility and market factors affecting transitions of nursing home residents back to the community. Multilevel models were used to estimate effects of facility and market factors on facility-level community discharge rates after controlling for resident demographic, health, and functional conditions. Facility discharge rates were adjusted using Empirical Bayes estimation. Annual cohort of first-time admissions (N=24,648) to 378 Minnesota nursing facilities in 75 nursing home markets from July 2005 to June 2006. Community discharge within 90 days of admission; facility occupancy, payer mix, ownership, case-mix acuity, size, admissions from hospitals, nurse staffing level, and proportion of admissions preferring or having support to return to the community; and nursing market population size, average occupancy, market concentration, and availability of home and community-based services. Rates of community discharge (Empirical Bayes residual) were highest in facilities with more residents preferring community discharge, more Medicare days, higher nurse staffing levels, and higher occupancy. In addition, facilities had higher community discharge rates if they were located in markets with a greater ratio of home and community-based services recipients to nursing home residents and with larger populations. State Medicaid programs should undertake system-level interventions that encourage nursing facilities to reduce unused bed capacity, balance the mix of payers, invest in nurse staffing, and take other steps to promote community discharges. In addition, states should increase home and community-based services, particularly in markets with low community discharge rates.

  17. Determinants of use of health facility for childbirth in rural Hadiya zone, Southern Ethiopia.

    PubMed

    Asseffa, Netsanet Abera; Bukola, Fawole; Ayodele, Arowojolu

    2016-11-16

    Maternal mortality remains a major global public health concern despite many international efforts. Facility-based childbirth increases access to appropriate skilled attendance and emergency obstetric care services as the vast majority of obstetric complications occur during delivery. The purpose of the study was to determine the proportion of facility delivery and assess factors influencing utilization of health facility for childbirth. A cross-sectional study was conducted in two rural districts of Hadiya zone, southern Ethiopia. Participants who delivered within three years of the survey were selected by stratified random sampling. Trained interviewers administered a pre-tested semi-structured questionnaire. We employed bivariate analysis and logistic regression to identify determinants of facility-based delivery. Data from 751 participants showed that 26.9% of deliveries were attended in health facilities. In bivariate analysis, maternal age, education, husband's level of education, possession of radio, antenatal care, place of recent ANC attended, planned pregnancy, wealth quintile, parity, birth preparedness and complication readiness, being a model family and distance from the nearest health facility were associated with facility delivery. On multiple logistic regression, age, educational status, antenatal care, distance from the nearest health facility, wealth quintile, being a model family, planned pregnancy and place of recent ANC attended were the determinants of facility-based childbirth. Efforts to improve institutional deliveries in the region must strengthen initiatives that promote female education, opportunities for wealth creation, female empowerment and increased uptake of family planning among others. Service related barriers and cultural influences on the use of health facility for childbirth require further evaluation.

  18. Overview taken from Facility 2 looking east down Avenue E ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overview taken from Facility 2 looking east down Avenue E (Russell Avenue). Facility 1 is on left, Facility 1G and 1C in center. View facing east - U.S. Naval Base, Pearl Harbor, Administration Annex, Near Russell Avenue (previously Avenue E), between of Facility Nos. 1C & 1E , Pearl City, Honolulu County, HI

  19. Ergonomics and simulation-based approach in improving facility layout

    NASA Astrophysics Data System (ADS)

    Abad, Jocelyn D.

    2018-02-01

    The use of the simulation-based technique in facility layout has been a choice in the industry due to its convenience and efficient generation of results. Nevertheless, the solutions generated are not capable of addressing delays due to worker's health and safety which significantly impact overall operational efficiency. It is, therefore, critical to incorporate ergonomics in facility design. In this study, workstation analysis was incorporated into Promodel simulation to improve the facility layout of a garment manufacturing. To test the effectiveness of the method, existing and improved facility designs were measured using comprehensive risk level, efficiency, and productivity. Results indicated that the improved facility layout generated a decrease in comprehensive risk level and rapid upper limb assessment score; an increase of 78% in efficiency and 194% increase in productivity compared to existing design and thus proved that the approach is effective in attaining overall facility design improvement.

  20. Shaw Air Force Base Capital Improvement Program Environmental Assessment

    DTIC Science & Technology

    2010-05-01

    storage tank VOC volatile organic compound WINDO Wing Infrastructure Development Outlook WWTP Wastewater Treatment Plant FINDING OF NO...efficiency and synergy. Outdated facilities would be demolished to provide opportunities for future base development . No additional personnel would be...facilities. The demolition of outdated facilities would provide more opportunities for future development that would be more consistent with existing land

  1. Credit BG. Northeast and northwest facades of Building 4496 (Security ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. Northeast and northwest facades of Building 4496 (Security Facility) as seen when looking south (178°) from entrance to secured area. The Control Tower (Building 4500) appears in background. The Security Facility is part of the secured Building 4505 complex - Edwards Air Force Base, North Base, Security Facility, Northeast of A Street, Boron, Kern County, CA

  2. Reducing Operating Costs by Optimizing Space in Facilities

    DTIC Science & Technology

    2012-03-01

    Base level 5 engineering units will provide facility floor plans, furniture layouts, and staffing documentation as necessary. One obstacle...due to the quantity and diverse locations. Base level engineering units provided facility floor plans, furniture layouts, and staffing documentation... furniture purchases and placement 5. Follow a quality systematic process in all decisions The per person costs can be better understood with a real

  3. Evaluation and use of U.S. Environmental Protection Agency Clean Watersheds Needs Survey data to quantify nutrient loads to surface water, 1978–2012

    USGS Publications Warehouse

    Ivahnenko, Tamara I.

    2017-12-07

    Changes in municipal and industrial point-source discharges over time have been an important factor affecting nutrient trends in many of the Nation’s streams and rivers. This report documents how three U.S. Environmental Protection Agency (EPA) national datasets—the Permit Compliance System, the Integrated Compliance Information System, and the Clean Watersheds Needs Survey—were evaluated for use in the U.S. Geological Survey National Water-Quality Assessment project to assess the causes of nutrient trends. This report also describes how a database of total nitrogen load and total phosphorous load was generated for select wastewater treatment facilities in the United States based on information reported in the EPA Clean Watersheds Needs Survey. Nutrient loads were calculated for the years 1978, 1980, 1982, 1984, 1986, 1988, 1990, 1992, 1996, 2000, 2004, 2008, and 2012 based on average nitrogen and phosphorous concentrations for reported treatment levels and on annual reported flow values.The EPA Permit Compliance System (PCS) and Integrated Compliance Information System (ICIS), which monitor point-source facility discharges, together are the Nation’s most spatially comprehensive dataset for nutrients released to surface waters. However, datasets for many individual facilities are incomplete, the PCS/ICIS historical data date back only to 1989, and historical data are available for only a limited number of facilities. Additionally, inconsistencies in facility reporting make it difficult to track or identify changes in nutrient discharges over time. Previous efforts made by the U.S. Geological Survey to “fill in” gaps in the PCS/ICIS data were based on statistical methods—missing data were filled in through the use of a statistical model based on the Standard Industrial Classification code, size, and flow class of the facility and on seasonal nutrient discharges of similar facilities. This approach was used to estimate point-source loads for a single point in time; it was not evaluated for use in generating a consistent data series over time.Another national EPA dataset that is available is the Clean Watersheds Needs Survey (CWNS), conducted every 4 years beginning 1973. The CWNS is an assessment of the capital needs of wastewater facilities to meet the water-quality goals set in the Clean Water Act. Data collected about these facilities include location and contact information for the facilities; population served; flow and treatment level of the facility; estimated capital needs to upgrade, repair, or improve facilities for water quality; and nonpoint-source best management practices.Total nitrogen and total phosphorous load calculations for each of the CWNS years were based on treatment level information and average annual outflow (in million gallons per day) from each of the facilities that had reported it. Treatment levels categories (such as Primary, Secondary, or Advanced) were substituted with average total nitrogen and total phosphorous concentrations for each treatment level based on those reported in literature. The CWNS dataset, like the PCS/ICIS dataset, has years where facilities did not report either a treatment level or an annual average outflow, or both. To fill in the data gaps, simple linear assumptions were made based on each facility’s responses to the survey in years bracketing the data gap or immediately before or after the data gap if open ended. Treatment level and flow data unique to each facility were used to complete the CWNS dataset for that facility.

  4. Health and Safety Management for Small-scale Methane Fermentation Facilities

    NASA Astrophysics Data System (ADS)

    Yamaoka, Masaru; Yuyama, Yoshito; Nakamura, Masato; Oritate, Fumiko

    In this study, we considered health and safety management for small-scale methane fermentation facilities that treat 2-5 ton of biomass daily based on several years operation experience with an approximate capacity of 5 t·d-1. We also took account of existing knowledge, related laws and regulations. There are no qualifications or licenses required for management and operation of small-scale methane fermentation facilities, even though rural sewerage facilities with a relative similar function are required to obtain a legitimate license. Therefore, there are wide variations in health and safety consciousness of the operators of small-scale methane fermentation facilities. The industrial safety and health laws are not applied to the operation of small-scale methane fermentation facilities. However, in order to safely operate a small-scale methane fermentation facility, the occupational safety and health management system that the law recommends should be applied. The aims of this paper are to clarify the risk factors in small-scale methane fermentation facilities and encourage planning, design and operation of facilities based on health and safety management.

  5. Human use regulatory affairs advisor (HURAA): learning about research ethics with intelligent learning modules.

    PubMed

    Hu, Xiangen; Graesser, Arthur C

    2004-05-01

    The Human Use Regulatory Affairs Advisor (HURAA) is a Web-based facility that provides help and training on the ethical use of human subjects in research, based on documents and regulations in United States federal agencies. HURAA has a number of standard features of conventional Web facilities and computer-based training, such as hypertext, multimedia, help modules, glossaries, archives, links to other sites, and page-turning didactic instruction. HURAA also has these intelligent features: (1) an animated conversational agent that serves as a navigational guide for the Web facility, (2) lessons with case-based and explanation-based reasoning, (3) document retrieval through natural language queries, and (4) a context-sensitive Frequently Asked Questions segment, called Point & Query. This article describes the functional learning components of HURAA, specifies its computational architecture, and summarizes empirical tests of the facility on learners.

  6. Gemini base facility operations environmental monitoring: key systems and tools for the remote operator

    NASA Astrophysics Data System (ADS)

    Cordova, Martin; Serio, Andrew; Meza, Francisco; Arriagada, Gustavo; Swett, Hector; Ball, Jesse; Collins, Paul; Masuda, Neal; Fuentes, Javier

    2016-07-01

    In 2014 Gemini Observatory started the base facility operations (BFO) project. The project's goal was to provide the ability to operate the two Gemini telescopes from their base facilities (respectively Hilo, HI at Gemini North, and La Serena, Chile at Gemini South). BFO was identified as a key project for Gemini's transition program, as it created an opportunity to reduce operational costs. In November 2015, the Gemini North telescope started operating from the base facility in Hilo, Hawaii. In order to provide the remote operator the tools to work from the base, many of the activities that were normally performed by the night staff at the summit were replaced with new systems and tools. This paper describes some of the key systems and tools implemented for environmental monitoring, and the design used in the implementation at the Gemini North telescope.

  7. Environmental Assessment for Construction and Repair of Fuel Storage and Offloading Facilities at Kirtland Air Force Base

    DTIC Science & Technology

    2005-09-01

    G Ot-T GOO) D. BRENT WILSON, P.E. Base Civil Engineer Kirtland Air Force Base Kirtland AFB Fuel Storage and Ofjloading Facilities Construction...September 2005 A-1 3 77 MSG/CEVQ DEPARTMENT OF THE AIR FORCE 3 77th Civil Engineer Division (AFMC) 2050 Wyoming Blvd SE, Suite 120 Kirtland AFB NM...FINAL FINDING OF NO SIGNIFICANT IMPACT FOR THE FOR CONSTRUCTION AND REP AIR OF FUEL STORAGE AND OFFLOADING FACILITIES AT KIRTLAND AIR FORCE

  8. User Evaluation of Biospice

    DTIC Science & Technology

    2006-10-01

    pipe facilities). The Dashboard is based on the NetBeans application platform, a Java-based tool kit. Tools may be written in any language...manner loosely analogous to UNIX shells (especially with respect to UNIX pipe facilities). The Dashboard is based on the NetBeans application

  9. National facilities study. Volume 2: Task group on aeronautical research and development facilities report

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The Task Group on Aeronautics R&D Facilities examined the status and requirements for aeronautics facilities against the competitive need. Emphasis was placed on ground-based facilities for subsonic, supersonic and hypersonic aerodynamics, and propulsion. Subsonic and transonic wind tunnels were judged to be most critical and of highest priority. Results of the study are presented.

  10. Modular Extended-Stay HyperGravity Facility Design Concept: An Artificial-Gravity Space-Settlement Ground Analogue

    NASA Technical Reports Server (NTRS)

    Dorais, Gregory A.

    2015-01-01

    This document defines the design concept for a ground-based, extended-stay hypergravity facility as a precursor for space-based artificial-gravity facilities that extend the permanent presence of both human and non-human life beyond Earth in artificial-gravity settlements. Since the Earth's current human population is stressing the environment and the resources off-Earth are relatively unlimited, by as soon as 2040 more than one thousand people could be living in Earthorbiting artificial-gravity habitats. Eventually, the majority of humanity may live in artificialgravity habitats throughout this solar system as well as others, but little is known about the longterm (multi-generational) effects of artificial-gravity habitats on people, animals, and plants. In order to extend life permanently beyond Earth, it would be useful to create an orbiting space facility that generates 1g as well as other gravity levels to rigorously address the numerous challenges of such an endeavor. Before doing so, developing a ground-based artificial-gravity facility is a reasonable next step. Just as the International Space Station is a microgravity research facility, at a small fraction of the cost and risk a ground-based artificial-gravity facility can begin to address a wide-variety of the artificial-gravity life-science questions and engineering challenges requiring long-term research to enable people, animals, and plants to live off-Earth indefinitely.

  11. Wound center facility billing: A retrospective analysis of time, wound size, and acuity scoring for determining facility level of service.

    PubMed

    Fife, Caroline E; Walker, David; Farrow, Wade; Otto, Gordon

    2007-01-01

    Outpatient wound center facility reimbursement for Medicare beneficiaries can be a challenge to determine and obtain. To compare methods of calculating facility service levels for outpatient wound centers and to demonstrate the advantages of an acuity-based billing system (one that incorporates components of facility work that is non-reimbursable by procedure codes and that represents an activity-based costing approach to medical billing), a retrospective study of 5,098 patient encounters contained in a wound care-specific electronic medical record database was conducted. Approximately 500 patient visits to the outpatient wound center of a Texas regional hospital between April 2003 and November 2004 were categorized by service level in documentation and facility management software. Visits previously billed using a time-based system were compared to the Centers for Medicare and Medicaid Services' proposed three-tiered wound size-based system. The time-based system also was compared to an acuity-based scoring system. The Pearson correlation coefficient between billed level of service by time and estimated level of service by acuity was 0.442 and the majority of follow-up visits were billed as Level 3 and above (on a time level of 1 to 5) , confirming that time is not a surrogate for actual work performed. Wound size also was found to be unrelated to service level (Pearson correlation = 0.017) and 97% of wound areas were < 100 cm2. The acuity-based scoring system produced a near-normal distribution of results, producing more mid-range billings than extremes; no other method produced this distribution. Hospital-based outpatient wound centers should develop, review, and refine acuity score-based models on which to determine billed level of service.

  12. Cyber Mutual Assistance Workshop Report

    DTIC Science & Technology

    2018-02-01

    Information Technology, Nuclear Reactors, Materials/Waste, Defense Industrial Base, Critical Manufacturing, Food/ Agriculture Government Facilities and...Manufacturing, Food/ Agriculture Government Facilities and Chemical, Commercial Facilities [DHS 2017c]. Distributed Energy Resources (DER) are

  13. Uptake and linkage into care over one year of providing HIV testing and counselling through community and health facility testing modalities in urban informal settlement of Kibera, Nairobi Kenya.

    PubMed

    Muhula, Samuel; Memiah, Peter; Mbau, Lilian; Oruko, Happiness; Baker, Bebora; Ikiara, Geoffrey; Mungai, Margaret; Ndirangu, Meshack; Achwoka, Dunstan; Ilako, Festus

    2016-05-04

    We examine the uptake of HIV Testing and Counselling (HTC) and linkage into care over one year of providing HTC through community and health facility testing modalities among people living in Kibera informal urban settlement in Nairobi Kenya. We analyzed program data on health facility-based HIV testing and counselling and community- based testing and counselling approaches for the period starting October 2013 to September 2014. Univariate and bivariate analysis methods were used to compare the two approaches with regard to uptake of HTC and subsequent linkage to care. The exact Confidence Intervals (CI) to the proportions were approximated using simple normal approximation to binomial distribution method. Majority of the 18,591 clients were tested through health facility-based testing approaches 72.5 % (n = 13485) vs those tested through community-based testing comprised 27.5 % (n = 5106). More clients tested at health facilities were reached through Provider Initiated Testing and Counselling PITC 81.7 % (n = 11015) while 18.3 % were reached through Voluntary Counselling and Testing (VCT)/Client Initiated Testing and Counselling (CITC) services. All clients who tested positive during health facility-based testing were successfully linked to care either at the project sites or sites of client choice while not all who tested positive during community based testing were linked to care. The HIV prevalence among all those who were tested for HIV in the program was 5.2 % (n = 52, 95 % CI: 3.9 %-6.8 %). Key study limitation included use of aggregate data to report uptake of HTC through the two testing approaches and not being able to estimate the population in the catchment area likely to test for HIV. Health facility-based HTC approach achieved more clients tested for HIV, and this method also resulted in identifying greater numbers of people who were HIV positive in Kibera slum within one year period of testing for HIV compared to community-based HTC approach. Linking HIV positive clients to care proved much easier during health facility- based HTC compared to community- based HTC.

  14. Reference Materials for Trace Element Microanalysis of Carbonates by SIMS and other Mass Spectrometric Techniques

    NASA Astrophysics Data System (ADS)

    Layne, G. D.

    2009-12-01

    Today, many areas of geochemical research utilize microanalytical determinations of trace elements in carbonate minerals. In particular, there has been an explosion in the application of Secondary Ion Mass Spectrometry (SIMS) to studies of marine biomineralization. SIMS provides highly precise determinations of Mg and Sr at the concentration levels normally encountered in corals, mollusks or fish otoliths. It is also a highly effective means for determining a wide range of other trace elements at ppm levels (e.g., Na, Fe, Mn, Ba, REE, Pb, Th, and U) in a variety of naturally occurring calcite and aragonite matrices - and so is potentially valuable in studies of diagenesis, hydrothermal fluids and carbonatitic magmas. For SIMS, modest time per spot (often <5 min), lateral spatial resolution (<10 μm), sample volume consumption (<10 ng) and overall reproducibility compare extremely favorably with other microanalytical techniques for these applications. However, accuracy and reproducibility are currently wholly limited by the homogeneity of available solid reference material - which is far inferior to the tenths of a percent levels of precision achieved by SIMS. Due to variation in the sputtered ion yields of most elements with the major element composition of the sample matrix, accuracy of SIMS depends intimately on matrix-matched solid reference materials. Despite its rapidly increasing use for trace element analyses of carbonates, there remains a dearth of certified reference materials suitable for calibrating SIMS. The pressed powders used by some analysts to calibrate LA-ICP-MS do not perform well for SIMS - they are not perfectly dense or homogeneous to the desired level at the micron scale of sampling. Further, they often prove incompatible with the sample high vacuum compatibility requirement for stable SIMS analysis (10-8 to 10-9 torr). Some naturally occurring calcite has apparent utility as a reference material. For example, equigranular calcite from some zones of carbonatite intrusions (sovites) and recrystallized calcites from highly metamorphosed metallic ore deposits. Most calcite marbles, though possibly appropriate as Sr standards, show substantial inhomogeneity in Mg, Mn and Ba. Some hydrothermal “Iceland Spar” calcite may prove useful as a reference for extremely low concentrations of Mg, Sr and Ba. The best carbonatitic calcites currently in use appear homogeneous to better than 2-3% for Sr (and somewhat less homogeneous for Mg). But these standards still require numerous replicate analyses during analytical sessions to reduce the overall uncertainty to <<1.0%.The availability of appropriate certified solid reference materials with a high degree of homogeneity would greatly benefit the utilization and inter-comparison of SIMS determinations in carbonates, while substantially reducing the time consumed in calibration. Some studies would also benefit from the extension of this effort to the characterization of appropriate standards of other rhombohedral carbonates (especially dolomite and Fe-rich calcite).

  15. Development of laboratory testing facility for evaluation of base-soil behavior under repeated loading : phase-1 : feasibility study.

    DOT National Transportation Integrated Search

    2008-03-01

    The main objective of this study was to determine the most beneficial and cost-effective accelerated load facility that can be used in conjunction with LTRCs Accelerated Load Facility (ALF). The facility will be used primarily for conducting preli...

  16. The ICCB Computer Based Facilities Inventory & Utilization Management Information Subsystem.

    ERIC Educational Resources Information Center

    Lach, Ivan J.

    The Illinois Community College Board (ICCB) Facilities Inventory and Utilization subsystem, a part of the ICCB management information system, was designed to provide decision makers with needed information to better manage the facility resources of Illinois community colleges. This subsystem, dependent upon facilities inventory data and course…

  17. FACILITY 89. WEST FRONT. U.S. Naval Base, Pearl Harbor, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FACILITY 89. WEST FRONT. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Makalapa, Junior Officers' Quarters Type K, Makin Place, & Halawa, Makalapa, & Midway Drives, Pearl City, Honolulu County, HI

  18. Cost and quality of life analysis of HIV self-testing and facility-based HIV testing and counselling in Blantyre, Malawi.

    PubMed

    Maheswaran, Hendramoorthy; Petrou, Stavros; MacPherson, Peter; Choko, Augustine T; Kumwenda, Felistas; Lalloo, David G; Clarke, Aileen; Corbett, Elizabeth L

    2016-02-19

    HIV self-testing (HIVST) has been found to be highly effective, but no cost analysis has been undertaken to guide the design of affordable and scalable implementation strategies. Consecutive HIV self-testers and facility-based testers were recruited from participants in a community cluster-randomised trial ( ISRCTN02004005 ) investigating the impact of offering HIVST in addition to facility-based HIV testing and counselling (HTC). Primary costing studies were undertaken of the HIVST service and of health facilities providing HTC to the trial population. Costs were adjusted to 2014 US$ and INT$. Recruited participants were asked about direct non-medical and indirect costs associated with accessing either modality of HIV testing, and additionally their health-related quality of life was measured using the EuroQol EQ-5D. A total of 1,241 participants underwent either HIVST (n = 775) or facility-based HTC (n = 446). The mean societal cost per participant tested through HIVST (US$9.23; 95 % CI: US$9.14-US$9.32) was lower than through facility-based HTC (US$11.84; 95 % CI: US$10.81-12.86). Although the mean health provider cost per participant tested through HIVST (US$8.78) was comparable to facility-based HTC (range: US$7.53-US$10.57), the associated mean direct non-medical and indirect cost was lower (US$2.93; 95 % CI: US$1.90-US$3.96). The mean health provider cost per HIV positive participant identified through HIVST was higher (US$97.50) than for health facilities (range: US$25.18-US$76.14), as was the mean cost per HIV positive individual assessed for anti-retroviral treatment (ART) eligibility and the mean cost per HIV positive individual initiated onto ART. In comparison to the facility-testing group, the adjusted mean EQ-5D utility score was 0.046 (95 % CI: 0.022-0.070) higher in the HIVST group. HIVST reduces the economic burden on clients, but is a costlier strategy for the health provider aiming to identify HIV positive individuals for treatment. The provider cost of HIVST could be substantially lower under less restrictive distribution models, or if costs of oral fluid HIV test kits become comparable to finger-prick kits used in health facilities.

  19. Underwater Facilities Inspection and Assessment at Magnetic Silencing Facility, Naval Submarine Base, Trident Support Site, Bangor, Washington.

    DTIC Science & Technology

    1980-10-01

    failure was noted in any other area of the facility. :’.. - . - ..- UNDERWATER FACILITI ES INSPECTION AND ASSESSMENT AT S- MAGNETIC SILENCING FACILITY...piling were found to be in excellent condition. No damage or failure was noted in any other * area of the facility. EXECUTIVE SUI’IARY TABLE U Piling...5-1 LEGEND TO TABLES. .... ........... ........ T-1 - -TABLE 1: REMAINING CROSS-SECTIONAL AREA AND DESCRIPTION OF DAMAGE TO

  20. Space technology test facilities at the NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R.; Rodrigues, Annette T.

    1990-01-01

    The major space research and technology test facilities at the NASA Ames Research Center are divided into five categories: General Purpose, Life Support, Computer-Based Simulation, High Energy, and the Space Exploraton Test Facilities. The paper discusses selected facilities within each of the five categories and discusses some of the major programs in which these facilities have been involved. Special attention is given to the 20-G Man-Rated Centrifuge, the Human Research Facility, the Plant Crop Growth Facility, the Numerical Aerodynamic Simulation Facility, the Arc-Jet Complex and Hypersonic Test Facility, the Infrared Detector and Cryogenic Test Facility, and the Mars Wind Tunnel. Each facility is described along with its objectives, test parameter ranges, and major current programs and applications.

  1. 77 FR 1087 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Reinstatement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... offender facilities (except in California); vocational training facilities; prison hospitals; drug and... facility. Based on the preference of the respondent, these data can be submitted via an electronic datafile...

  2. 24 CFR 982.613 - Group home: Rent and voucher housing assistance payment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM... facilities for food preparation and service, are common facilities or private facilities. (c) Payment...

  3. A new AMS facility at Inter University Accelerator Centre, New Delhi

    NASA Astrophysics Data System (ADS)

    Kumar, Pankaj; Chopra, S.; Pattanaik, J. K.; Ojha, S.; Gargari, S.; Joshi, R.; Kanjilal, D.

    2015-10-01

    Inter University Accelerator Centre (IUAC), a national facility of government of India, is having a 15UD Pelletron accelerator for multidisciplinary ion beam based research programs. Recently, a new accelerator mass spectrometry (AMS) facility has been developed after incorporating many changes in the existing 15UD Pelletron accelerator. A clean chemistry laboratory for 10Be and 26Al with all the modern facilities has also been developed for the chemical processing of samples. 10Be measurements on sediment samples, inter laboratory comparison results and 26Al measurements on standard samples are presented in this paper. In addition to the 10Be and 26Al AMS facilities, a new 14C AMS facility based on a dedicated 500 kV tandem ion accelerator with two cesium sputter ion sources, is also being setup at IUAC.

  4. Environmental Assessment (EA): Proposed Software Facilities, Hill Air Force Base, Utah

    DTIC Science & Technology

    2011-04-19

    retention facilities ; • connections to adjacent buried utilities consisting of water, electricity, natural gas, telephone/ data , sanitary sewer, and storm...engineering, development, and testing workloads for F-22 and F-35 aircraft. Military construction (MILCON) project data explain existing facilities ...Existing Facilities MILCON project data state there are no facilities on Hill AFB with adequate security to house the specialized laboratory space or

  5. Increase in facility-based deliveries associated with a maternal health voucher programme in informal settlements in Nairobi, Kenya

    PubMed Central

    Bellows, Ben; Kyobutungi, Catherine; Mutua, Martin Kavao; Warren, Charlotte; Ezeh, Alex

    2013-01-01

    Objective To measure whether there was an association between the introduction of an output-based voucher programme and the odds of a facility-based delivery in two Nairobi informal settlements. Data sources Nairobi Urban Health and Demographic Surveillance System (NUHDSS) and two cross-sectional household surveys in Korogocho and Viwandani informal settlements in 2004–05 and 2006–08. Methods Odds of facility-based delivery were estimated before and after introduction of an output-based voucher. Supporting NUHDSS data were used to determine whether any trend in maternal health care was coincident with immunizations, a non-voucher outpatient service. As part of NUHDSS, households in Korogocho and Viwandani reported place of delivery and the presence of a skilled birth attendant (2003–10) and vaccination coverage (2003–09). A detailed maternal and child health (MCH) tool was added to NUHDSS (September 2006–10). Prospective enrolment in NUHDSS-MCH was conditional on having a newborn after September 2006. In addition to recording mother’s place of delivery, NUHDSS-MCH recorded the use of the voucher. Findings There were significantly greater odds of a facility-based delivery among respondents during the voucher programme compared with similar respondents prior to voucher launch. Testing whether unrelated outpatient care also increased, a falsification exercise found no significant increase in immunizations for children 12–23 months of age in the same period. Although the proportion completing any antenatal care (ANC) visit remained above 95% of all reported pregnancies and there was a significant increase in facility-based deliveries, the proportion of women completing 4+ ANC visits was significantly lower during the voucher programme. Conclusions A positive association was observed between vouchers and facility-based deliveries in Nairobi. Although there is a need for higher quality evidence and validation in future studies, this statistically significant and policy relevant finding suggests that increases in facility-based deliveries can be achieved through output-based finance models that target subsidies to underserved populations. PMID:22437506

  6. Scaling laws between population and facility densities.

    PubMed

    Um, Jaegon; Son, Seung-Woo; Lee, Sung-Ik; Jeong, Hawoong; Kim, Beom Jun

    2009-08-25

    When a new facility like a grocery store, a school, or a fire station is planned, its location should ideally be determined by the necessities of people who live nearby. Empirically, it has been found that there exists a positive correlation between facility and population densities. In the present work, we investigate the ideal relation between the population and the facility densities within the framework of an economic mechanism governing microdynamics. In previous studies based on the global optimization of facility positions in minimizing the overall travel distance between people and facilities, it was shown that the density of facility D and that of population rho should follow a simple power law D approximately rho(2/3). In our empirical analysis, on the other hand, the power-law exponent alpha in D approximately rho(alpha) is not a fixed value but spreads in a broad range depending on facility types. To explain this discrepancy in alpha, we propose a model based on economic mechanisms that mimic the competitive balance between the profit of the facilities and the social opportunity cost for populations. Through our simple, microscopically driven model, we show that commercial facilities driven by the profit of the facilities have alpha = 1, whereas public facilities driven by the social opportunity cost have alpha = 2/3. We simulate this model to find the optimal positions of facilities on a real U.S. map and show that the results are consistent with the empirical data.

  7. Development and Validation of Pathogen Environmental Monitoring Programs for Small Cheese Processing Facilities.

    PubMed

    Beno, Sarah M; Stasiewicz, Matthew J; Andrus, Alexis D; Ralyea, Robert D; Kent, David J; Martin, Nicole H; Wiedmann, Martin; Boor, Kathryn J

    2016-12-01

    Pathogen environmental monitoring programs (EMPs) are essential for food processing facilities of all sizes that produce ready-to-eat food products exposed to the processing environment. We developed, implemented, and evaluated EMPs targeting Listeria spp. and Salmonella in nine small cheese processing facilities, including seven farmstead facilities. Individual EMPs with monthly sample collection protocols were designed specifically for each facility. Salmonella was detected in only one facility, with likely introduction from the adjacent farm indicated by pulsed-field gel electrophoresis data. Listeria spp. were isolated from all nine facilities during routine sampling. The overall Listeria spp. (other than Listeria monocytogenes ) and L. monocytogenes prevalences in the 4,430 environmental samples collected were 6.03 and 1.35%, respectively. Molecular characterization and subtyping data suggested persistence of a given Listeria spp. strain in seven facilities and persistence of L. monocytogenes in four facilities. To assess routine sampling plans, validation sampling for Listeria spp. was performed in seven facilities after at least 6 months of routine sampling. This validation sampling was performed by independent individuals and included collection of 50 to 150 samples per facility, based on statistical sample size calculations. Two of the facilities had a significantly higher frequency of detection of Listeria spp. during the validation sampling than during routine sampling, whereas two other facilities had significantly lower frequencies of detection. This study provides a model for a science- and statistics-based approach to developing and validating pathogen EMPs.

  8. Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility.

    PubMed

    Williamson, Nicholas A

    2018-03-01

    This paper discusses the successful adoption of a subscription-based, open-access model of service delivery for a mass spectrometry and proteomics facility. In 2009, the Mass Spectrometry and Proteomics Facility at the University of Melbourne (Australia) moved away from the standard fee for service model of service provision. Instead, the facility adopted a subscription- or membership-based, open-access model of service delivery. For a low fixed yearly cost, users could directly operate the instrumentation but, more importantly, there were no limits on usage other than the necessity to share available instrument time with all other users. All necessary training from platform staff and many of the base reagents were also provided as part of the membership cost. These changes proved to be very successful in terms of financial outcomes for the facility, instrument access and usage, and overall research output. This article describes the systems put in place as well as the overall successes and challenges associated with the operation of a mass spectrometry/proteomics core in this manner. Graphical abstract ᅟ.

  9. Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility

    NASA Astrophysics Data System (ADS)

    Williamson, Nicholas A.

    2018-03-01

    This paper discusses the successful adoption of a subscription-based, open-access model of service delivery for a mass spectrometry and proteomics facility. In 2009, the Mass Spectrometry and Proteomics Facility at the University of Melbourne (Australia) moved away from the standard fee for service model of service provision. Instead, the facility adopted a subscription- or membership-based, open-access model of service delivery. For a low fixed yearly cost, users could directly operate the instrumentation but, more importantly, there were no limits on usage other than the necessity to share available instrument time with all other users. All necessary training from platform staff and many of the base reagents were also provided as part of the membership cost. These changes proved to be very successful in terms of financial outcomes for the facility, instrument access and usage, and overall research output. This article describes the systems put in place as well as the overall successes and challenges associated with the operation of a mass spectrometry/proteomics core in this manner. [Figure not available: see fulltext.

  10. INCINERATION RESEARCH FACILITY

    EPA Science Inventory

    The Cincinnati-based Risk Reduction Engineering Laboratory, ORD, U.S. EPA operates the Incineration Research Facility *IRF) in Jefferson, Arkansas. This facility's pilot-scale experimental incineration systems include a Rotary Kiln System and a Liquid Injection System. Each syste...

  11. 76 FR 67224 - Agency Information Collection Activities; Proposed Collection, Comments Requested: Reinstatement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... conservation camps; youthful offender facilities (except in California); vocational training facilities; prison... plans to modify or close the facility. Based on the preference of the respondent, these data can be...

  12. A performance goal-based seismic design philosophy for waste repository facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hossain, Q.A.

    1994-12-31

    A performance goal-based seismic design philosophy, compatible with DOE`s present natural phenomena hazards mitigation and {open_quotes}graded approach{close_quotes} philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed.

  13. Environmental Assessment: Proposed Automotive/Arts and Crafts Skills Center, Hill Air Force Base, Utah

    DTIC Science & Technology

    2010-10-14

    Water regarding potential sources of t practices to ensure drinking water source protection. u ity design and operating standards would be based...center would not be constructed, and adequate facilities would not be provided. The existing facility would operate as it currently exists...would be properly handled during the construction process. Operational activities would generate the same types of waste as the existing facility

  14. 42 CFR 413.65 - Requirements for a determination that a facility or an organization has provider-based status.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... an organization has provider-based status. 413.65 Section 413.65 Public Health CENTERS FOR MEDICARE... or an organization has provider-based status. (a) Scope and definitions.(1) Scope. (i) This section applies to all facilities for which provider-based status is sought, including remote locations of...

  15. 76 FR 75453 - Restricted Areas and Danger Zones at Eglin Air Force Base, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... and Danger Zones at Eglin Air Force Base, FL AGENCY: U.S. Army Corps of Engineers, Department of... within the Eglin Air Force Base (AFB) facilities and along the Eglin AFB facility shoreline in Florida... have the permission of the Commander, 96 Air Base Wing, Eglin AFB or his/her authorized representative...

  16. ROYAL PALMLINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ROYAL PALM-LINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY 1040 (QUARTERS 1) TO LEFT. TAKEN AT CORNER OF HALE ALII AVENUE AND EIGHTH STREET. VIEW FACING EAST. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hale Alii, Hale Alii Avenue, Eighth Street, & Avenue D, Pearl City, Honolulu County, HI

  17. A Guide to Preparing Educational Specifications for Secondary Industrial Arts Facilities. Monograph No. 1.

    ERIC Educational Resources Information Center

    Steeb, Ralph V.

    The guide describes procedures for designing secondary industrial arts facilities based on careful scrutiny of the educational program which the facilities are intended to serve. It offers a four step general outline for planning such facilities and discusses in detail the following considerations with respect to writing subject area…

  18. A PLANNED COMMUNITY FOR MIGRATORY FARM WORKERS--A PROPOSAL FOR A DEMONSTRATION PROJECT.

    ERIC Educational Resources Information Center

    PEERY, A.B.

    A DEMONSTRATION PROJECT FOR MIGRATORY FARM LABORERS HOME-BASED IN SOUTH TEXAS IS PROPOSED. THE PURPOSE IS TO DESIGN A PLANNED COMMUNITY CONTAINING HOUSING, HEALTH FACILITIES, ORIENTATION AND EDUCATIONAL FACILITIES, JOB-PLACEMENT FACILITIES, AND SOCIAL, RECREATIONAL, AND COMMERCIAL FACILITIES. THE PLANNED COMMUNITY WOULD PROVIDE SAFE, SANITARY, AND…

  19. Legal requirements for human-health based appeals of wind energy projects in ontario.

    PubMed

    Engel, Albert M

    2014-01-01

    In 2009, the government of the province of Ontario, Canada passed new legislation to promote the development of renewable energy facilities, including wind energy facilities in the province. Throughout the legislative process, concerns were raised with respect to the effect of wind energy facilities on human health. Ultimately, the government established setbacks and sound level limits for wind energy facilities and provided Ontario residents with the right to appeal the approval of a wind energy facility on the ground that engaging in the facility in accordance with its approval will cause serious harm to human health. The first approval of a wind facility under the new legislation was issued in 2010 and since then, Ontario's Environmental Review Tribunal as well as Ontario's courts has been considering evidence proffered by appellants seeking revocation of approvals on the basis of serious harm to human health. To date, the evidence has been insufficient to support the revocation of a wind facility approval. This article reviews the legal basis for the dismissal of human-health based appeals.

  20. A free-piston Stirling engine/linear alternator controls and load interaction test facility

    NASA Technical Reports Server (NTRS)

    Rauch, Jeffrey S.; Kankam, M. David; Santiago, Walter; Madi, Frank J.

    1992-01-01

    A test facility at LeRC was assembled for evaluating free-piston Stirling engine/linear alternator control options, and interaction with various electrical loads. This facility is based on a 'SPIKE' engine/alternator. The engine/alternator, a multi-purpose load system, a digital computer based load and facility control, and a data acquisition system with both steady-periodic and transient capability are described. Preliminary steady-periodic results are included for several operating modes of a digital AC parasitic load control. Preliminary results on the transient response to switching a resistive AC user load are discussed.

  1. Minnesota's Nursing Facility Performance-Based Incentive Payment Program: An Innovative Model for Promoting Care Quality

    ERIC Educational Resources Information Center

    Cooke, Valerie; Arling, Greg; Lewis, Teresa; Abrahamson, Kathleen A.; Mueller, Christine; Edstrom, Lisa

    2010-01-01

    Purpose: Minnesota's Nursing Facility Performance-Based Incentive Payment Program (PIPP) supports provider-initiated projects aimed at improving care quality and efficiency. PIPP moves beyond conventional pay for performance. It seeks to promote implementation of evidence-based practices, encourage innovation and risk taking, foster collaboration…

  2. How women are treated during facility-based childbirth: development and validation of measurement tools in four countries - phase 1 formative research study protocol.

    PubMed

    Vogel, Joshua P; Bohren, Meghan A; Tunçalp, Özge; Oladapo, Olufemi T; Adanu, Richard M; Baldé, Mamadou Diouldé; Maung, Thae Maung; Fawole, Bukola; Adu-Bonsaffoh, Kwame; Dako-Gyeke, Phyllis; Maya, Ernest Tei; Camara, Mohamed Campell; Diallo, Alfa Boubacar; Diallo, Safiatou; Wai, Khin Thet; Myint, Theingi; Olutayo, Lanre; Titiloye, Musibau; Alu, Frank; Idris, Hadiza; Gülmezoglu, Metin A

    2015-07-22

    Every woman has the right to dignified, respectful care during childbirth. Recent evidence has demonstrated that globally many women experience mistreatment during labour and childbirth in health facilities, which can pose a significant barrier to women attending facilities for delivery and can contribute to poor birth experiences and adverse outcomes for women and newborns. However there is no clear consensus on how mistreatment of women during childbirth in facilities is defined and measured. We propose using a two-phased, mixed-methods study design in four countries to address these research gaps. This protocol describes the Phase 1 qualitative research activities. We will employ qualitative research methodologies among women, healthcare providers and administrators in the facility catchment areas of two health facilities in each country: Ghana, Guinea, Myanmar and Nigeria. In-depth interviews (IDIs) and focus group discussions (FGDs) will be conducted among women of reproductive age (15-49 years) to explore their perceptions and experiences of facility-based childbirth care, focused on how they were treated by healthcare workers and perceived factors affecting how they were treated. IDIs will also be conducted with healthcare providers of different cadres (e.g.: nurses, midwives, medical officers, specialist obstetricians) and facility administrators working in the selected facilities to explore healthcare providers' perceptions and experiences of facility-based childbirth care and how staff are treated, colleagues and supervisors. Audio recordings will be transcribed and translated to English. Textual data will be analysed using a thematic framework approach and will consist of two levels of analysis: (1) conduct of local analysis workshops with the research assistants in each country; and (2) line-by-line coding to develop a thematic framework and coding scheme. This study serves several roles. It will provide an in-depth understanding of how women are treated during childbirth in four countries and perceived factors associated with this mistreatment. It will also provide data on where and how an intervention could be developed to reduce mistreatment and promote respectful care. The findings from this study will contribute to the development of tools to measure the prevalence of mistreatment of women during facility-based childbirth.

  3. U.S. Naval Base, Pearl Harbor, Operations & Message Center, Behind ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    U.S. Naval Base, Pearl Harbor, Operations & Message Center, Behind Facility No. 1, corner of Avenue E & Seventh Street, connected to Facility Nos. 1B & 1D by wooden bridges, Pearl City, Honolulu County, HI

  4. Cryogenic Fluid Management Facility

    NASA Technical Reports Server (NTRS)

    Eberhardt, R. N.; Bailey, W. J.; Symons, E. P.; Kroeger, E. W.

    1984-01-01

    The Cryogenic Fluid Management Facility (CFMF) is a reusable test bed which is designed to be carried into space in the Shuttle cargo bay to investigate systems and technologies required to efficiently and effectively manage cryogens in space. The facility hardware is configured to provide low-g verification of fluid and thermal models of cryogenic storage, transfer concepts and processes. Significant design data and criteria for future subcritical cryogenic storage and transfer systems will be obtained. Future applications include space-based and ground-based orbit transfer vehicles (OTV), space station life support, attitude control, power and fuel depot supply, resupply tankers, external tank (ET) propellant scavenging, space-based weapon systems and space-based orbit maneuvering vehicles (OMV). This paper describes the facility and discusses the cryogenic fluid management technology to be investigated. A brief discussion of the integration issues involved in loading and transporting liquid hydrogen within the Shuttle cargo bay is also included.

  5. A survey of veterinary radiation facilities in 2010.

    PubMed

    Farrelly, John; McEntee, Margaret C

    2014-01-01

    A survey of veterinary radiation therapy facilities in the United States, Canada, and Europe was done in 2010, using an online survey tool, to determine the type of equipment available, radiation protocols used, caseload, tumor types irradiated, as well as other details of the practice of veterinary radiation oncology. The results of this survey were compared to a similar survey performed in 2001. A total of 76 facilities were identified including 24 (32%) academic institutions and 52 (68%) private practice external beam radiation therapy facilities. The overall response rate was 51% (39/76 responded). Based on this survey, there is substantial variation among facilities in all aspects ranging from equipment and personnel to radiation protocols and caseloads. American College of Veterinary Radiology boarded radiation oncologists direct 90% of the radiation facilities, which was increased slightly compared to 2001. All facilities surveyed in 2010 had a linear accelerator. More facilities reported having electron capability (79%) compared to the 2001 survey. Eight facilities had a radiation oncology resident, and academic facilities were more likely to have residents. Patient caseload information was available from 28 sites (37% of radiation facilities), and based on the responses 1376 dogs and 352 cats were irradiated in 2010. The most frequently irradiated tumors were soft tissue sarcomas in dogs, and oral squamous cell carcinoma in cats. © 2014 American College of Veterinary Radiology.

  6. Consumer Choice Between Hospital-Based and Freestanding Facilities for Arthroscopy: Impact on Prices, Spending, and Surgical Complications.

    PubMed

    Robinson, James C; Brown, Timothy T; Whaley, Christopher; Bozic, Kevin J

    2015-09-16

    Hospital-based outpatient departments traditionally charge higher prices for ambulatory procedures, compared with freestanding surgery centers. Under emerging reference-based benefit designs, insurers establish a contribution limit that they will pay, requiring the patient to pay the difference between that contribution limit and the actual price charged by the facility. The purpose of this study was to evaluate the impact of reference-based benefits on consumer choices, facility prices, employer spending, and surgical outcomes for orthopaedic procedures performed at ambulatory surgery centers. We obtained data on 3962 patients covered by the California Public Employees' Retirement System (CalPERS) who underwent arthroscopy of the knee or shoulder in the three years prior to the implementation of reference-based benefits in January 2012 and on 2505 patients covered by CalPERS who underwent arthroscopy in the two years after implementation. Control group data were obtained on 57,791 patients who underwent arthroscopy and were not subject to reference-based benefits. The impact of reference-based benefits on consumer choices between hospital-based and freestanding facilities, facility prices, employer spending, and surgical complications was assessed with use of difference-in-differences multivariable regressions to adjust for patient demographic characteristics, comorbidities, and geographic location. By the second year of the program, the shift to reference-based benefits was associated with an increase in the utilization of freestanding ambulatory surgery centers by 14.3 percentage points (95% confidence interval, 8.1 to 20.5 percentage points) for knee arthroscopy and by 9.9 percentage points (95% confidence interval, 3.2 to 16.7 percentage points) for shoulder arthroscopy and a corresponding decrease in the use of hospital-based facilities. The mean price paid by CalPERS fell by 17.6% (95% confidence interval, -24.9% to -9.6%) for knee procedures and by 17.0% (95% confidence interval, -29.3% to -2.5%) for shoulder procedures. The shift to reference-based benefits was not associated with a change in the rate of surgical complications. In the first two years after the implementation of reference-based benefits, CalPERS saved $2.3 million (13%) on these two orthopaedic procedures. Reference-based benefits increase consumer sensitivity to price differences between freestanding and hospital-based surgical facilities. This study shows that the implementation of reference-based benefits does not result in a significant increase in measured complication rates for those subject to reference-based benefits. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

  7. Consumer Choice Between Hospital-Based and Freestanding Facilities for Arthroscopy

    PubMed Central

    Robinson, James C.; Brown, Timothy T.; Whaley, Christopher; Bozic, Kevin J.

    2015-01-01

    Background: Hospital-based outpatient departments traditionally charge higher prices for ambulatory procedures, compared with freestanding surgery centers. Under emerging reference-based benefit designs, insurers establish a contribution limit that they will pay, requiring the patient to pay the difference between that contribution limit and the actual price charged by the facility. The purpose of this study was to evaluate the impact of reference-based benefits on consumer choices, facility prices, employer spending, and surgical outcomes for orthopaedic procedures performed at ambulatory surgery centers. Methods: We obtained data on 3962 patients covered by the California Public Employees’ Retirement System (CalPERS) who underwent arthroscopy of the knee or shoulder in the three years prior to the implementation of reference-based benefits in January 2012 and on 2505 patients covered by CalPERS who underwent arthroscopy in the two years after implementation. Control group data were obtained on 57,791 patients who underwent arthroscopy and were not subject to reference-based benefits. The impact of reference-based benefits on consumer choices between hospital-based and freestanding facilities, facility prices, employer spending, and surgical complications was assessed with use of difference-in-differences multivariable regressions to adjust for patient demographic characteristics, comorbidities, and geographic location. Results: By the second year of the program, the shift to reference-based benefits was associated with an increase in the utilization of freestanding ambulatory surgery centers by 14.3 percentage points (95% confidence interval, 8.1 to 20.5 percentage points) for knee arthroscopy and by 9.9 percentage points (95% confidence interval, 3.2 to 16.7 percentage points) for shoulder arthroscopy and a corresponding decrease in the use of hospital-based facilities. The mean price paid by CalPERS fell by 17.6% (95% confidence interval, −24.9% to −9.6%) for knee procedures and by 17.0% (95% confidence interval, −29.3% to −2.5%) for shoulder procedures. The shift to reference-based benefits was not associated with a change in the rate of surgical complications. In the first two years after the implementation of reference-based benefits, CalPERS saved $2.3 million (13%) on these two orthopaedic procedures. Conclusions: Reference-based benefits increase consumer sensitivity to price differences between freestanding and hospital-based surgical facilities. Clinical Relevance: This study shows that the implementation of reference-based benefits does not result in a significant increase in measured complication rates for those subject to reference-based benefits. PMID:26378263

  8. Societal-Equity-Enhancing Criteria and Facility-Host Incentives Supporting Five Key Elements in the January 2012 Blue Ribbon Commission Report - 13015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eriksson, Leif G.; Dials, George E.; George, Critz H.

    2013-07-01

    In February 2009, the Obama Administration announced it would abandon USA's only candidate SNF/HLW-disposal facility since 1987. In 2010, all related activities were stopped and the Blue Ribbon Commission on America's Nuclear Future was established 'to recommend a new strategy for managing the back end of the nuclear fuel cycle', which it did in January 2012, emphasizing eight key elements. However, Key Element 1, 'A new, consent-based approach to siting future nuclear facilities', is qualitative/indeterminate rather than quantitative/measurable. It is thus highly-susceptible to semantic permutations that could extend rather than, as intended, expedite the siting of future nuclear facilities unlessmore » it also defines: a) Whose consent is needed?; and b) What constitutes consent? The following 'generic', radiation-risk- and societal-equity-based criteria address these questions: 1. Identify areas affected by projected radiation and other health risks from: a. The proposed nuclear facility (facility stakeholders); and b. The related nuclear-materials-transportation routes (transportation stakeholders); then 2. Surround each stakeholder area with a buffer zone and use this enlarged foot print to identify: a. Stakeholder hosts; and b. Areas not hosting any stakeholder category (interested parties). 3. Define 'consent-based' as being at least 60 percent of the 'population' in the respective stakeholder category and apply this yardstick to both 'in favor' and 'against' votes. Although criteria 1 and 2 also need facility-based definitions to make Key Element 1 measurable, the described siting approach, augmented by related facility-host incentives, would expedite the schedule and reduce the cost for achieving Key Elements 4-6 and 8, politics permitting. (authors)« less

  9. Quality of Post-Acute Care in Skilled Nursing Facilities That Disproportionately Serve Black and Hispanic Patients.

    PubMed

    Rivera-Hernandez, Maricruz; Rahman, Momotazur; Mukamel, Dana B; Mor, Vincent; Trivedi, Amal N

    2018-04-25

    Understanding and addressing racial and ethnic disparities in the quality of post-acute care in skilled nursing facilities is an important health policy issue, particularly as the Medicare program initiates value-based payments for these institutions. Our final cohort included 649,187 Medicare beneficiaries in either the fee-for-service or Medicare Advantage programs, who were 65 and older and were admitted to a skilled nursing facility following an acute hospital stay, from 8,375 skilled nursing facilities. We examined the quality of care in skilled nursing facilities that disproportionately serve minority patients compared to non-Hispanic whites. Three measures, all calculated at the level of the facility, were used to assess quality of care in skilled nursing facilities: 1) 30-day rehospitalization rate; 2) successful discharge from the facility to the community; and 3) Medicare five-star quality ratings. We found that African-American post-acute patients are highly concentrated in a small number of institutions, with 28% of facilities accounting for 80% of all post-acute admissions for African-American patients. Similarly, just 20% of facilities accounted for 80% of all admissions for Hispanics. Skilled nursing facilities with higher fractions of African-American patients had worse performance for three publicly-reported quality measures: rehospitalization, successful discharge to the community, and the star rating indicator. Efforts to address disparities should focus attention on institutions that disproportionately serve minority patients and monitor unintended consequences of value-based payments to skilled nursing facilities.

  10. A standards-based approach to quality improvement for HIV services at Zambia Defence Force facilities: results and lessons learned.

    PubMed

    Kols, Adrienne; Kim, Young-Mi; Bazant, Eva; Necochea, Edgar; Banda, Joseph; Stender, Stacie

    2015-07-01

    The Zambia Defence Force adopted the Standards-Based Management and Recognition approach to improve the quality of the HIV-related services at its health facilities. This quality improvement intervention relies on comprehensive, detailed assessment tools to communicate and verify adherence to national standards of care, and to test and implement changes to improve performance. A quasi-experimental evaluation of the intervention was conducted at eight Zambia Defence Force primary health facilities (four facilities implemented the intervention and four did not). Data from three previous analyses are combined to assess the effect of Standards-Based Management and Recognition on three domains: facility readiness to provide services; observed provider performance during antiretroviral therapy (ART) and antenatal care consultations; and provider perceptions of the work environment. Facility readiness scores for ART improved on four of the eight standards at intervention sites, and one standard at comparison sites. Facility readiness scores for prevention of mother-to-child transmission (PMTCT) of HIV increased by 15 percentage points at intervention sites and 7 percentage points at comparison sites. Provider performance improved significantly at intervention sites for both ART services (from 58 to 84%; P < 0.01) and PMTCT services (from 58 to 73%; P = 0.003); there was no significant change at comparison sites. Providers' perceptions of the work environment generally improved at intervention sites and declined at comparison sites; differences in trends between study groups were significant for eight items. A standards-based approach to quality improvement proved effective in supporting healthcare managers and providers to deliver ART and PMTCT services in accordance with evidence-based standards in a health system suffering from staff shortages.

  11. Treatment of men with high-risk prostate cancer based on race, insurance coverage, and access to advanced technology

    PubMed Central

    Gerhard, R. Steven; Patil, Dattatraya; Liu, Yuan; Ogan, Kenneth; Alemozaffar, Mehrdad; Jani, Ashesh B.; Kucuk, Omer N.; Master, Viraj A.; Gillespie, Theresa W.; Filson, Christopher P.

    2017-01-01

    PURPOSE We characterized factors related to non-definitive management of high-risk prostate cancer patients, and assessed impact from race, insurance status, and facility-level volume of technologically-advanced prostate cancer treatments (i.e. intensity-modulated radiation therapy, robotic-assisted laparoscopic radical prostatectomy) on this outcome. METHODS We identified men with high-risk localized prostate cancer (based on D’Amico criteria) in the National Cancer Data Base (2010–2012). Primary outcome was non-definitive management (i.e., delayed/no treatment with prostatectomy/radiation therapy or androgen deprivation therapy monotherapy). Treating facilities were classified by quartiles of proportions of patients treated with advanced technology. Multivariable regression estimated odds of primary outcome based on race, insurance status, and facility-level technology use, and evaluated for interactions between these covariates. RESULTS Among 60,300 patients, 9265 (15.4%) received non-definitive management. This was more common among non-White men (p<0.001), Medicaid/uninsured patients (p<0.001), and those managed at facilities in the lowest quartile of technology use (25.1% vs 11.0% highest, p<0.001). Though non-definitive management was common among non-White men with Medicaid/no insurance treated at low-technology centers (43% vs 10% White, private/Medicare, high-tech facility; adjusted OR 7.18, p<0.001), this was less likely if this group was managed at a high-tech hospital (22% vs 43% low-tech, p<0.001). CONCLUSIONS Technology-use at a facility correlates with high-quality prostate cancer care, and is associated with diminished disparities based on insurance status and patient race. More research is required to characterize other facility-level factors explaining these findings. PMID:28089387

  12. A Study of Selected Issues in Military Construction and Base Operating Support

    DTIC Science & Technology

    1986-12-01

    and poten- tial, of data reported annually on the readiness of Navy shore base facilities * Development of a statistical model for forecasting the...of replacing or modernizing existing facilities * Study of the set of activities--including retail supply operations, bachelor housing, automated data ...until data from FY 1986 can be obtained and I SECTION 2 CAPITAL FACILITIES : AGING, REPLACEMENT, AND CHANGE OVER TIME During development of the POM, OP

  13. New Ground Based facilities in QSO research; The GTC

    NASA Astrophysics Data System (ADS)

    Rodriguez Espinosa, J. M.

    New ground based observing opportunities are becoming, or about to become, available to astronomers for QSO research. These, combined with state of the art focal plane instruments, provide unprecedented sensitivity for detecting faint surface brightness features. During the talk I will take the liberty of talking about one of these new large telescope facilities currently being built in Spain, and will discuss some of the advantages for QSO research offered by these new facilities.

  14. Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing Facilities for FY 2017, SNF Value-Based Purchasing Program, SNF Quality Reporting Program, and SNF Payment Models Research. Final rule.

    PubMed

    2016-08-05

    This final rule updates the payment rates used under the prospective payment system (PPS) for skilled nursing facilities (SNFs) for fiscal year (FY) 2017. In addition, it specifies a potentially preventable readmission measure for the Skilled Nursing Facility Value-Based Purchasing Program (SNF VBP), and implements requirements for that program, including performance standards, a scoring methodology, and a review and correction process for performance information to be made public, aimed at implementing value-based purchasing for SNFs. Additionally, this final rule includes additional polices and measures in the Skilled Nursing Facility Quality Reporting Program (SNF QRP). This final rule also responds to comments on the SNF Payment Models Research (PMR) project.

  15. Population-based geographic access to parent and satellite National Cancer Institute Cancer Center Facilities.

    PubMed

    Onega, Tracy; Alford-Teaster, Jennifer; Wang, Fahui

    2017-09-01

    Satellite facilities of National Cancer Institute (NCI) cancer centers have expanded their regional footprints. This study characterized geographic access to parent and satellite NCI cancer center facilities nationally overall and by sociodemographics. Parent and satellite NCI cancer center facilities, which were geocoded in ArcGIS, were ascertained. Travel times from every census tract in the continental United States and Hawaii to the nearest parent and satellite facilities were calculated. Census-based population attributes were used to characterize measures of geographic access for sociodemographic groups. From the 62 NCI cancer centers providing clinical care in 2014, 76 unique parent locations and 211 satellite locations were mapped. The overall proportion of the population within 60 minutes of a facility was 22% for parent facilities and 32.7% for satellite facilities. When satellites were included for potential access, the proportion of some racial groups for which a satellite was the closest NCI cancer center facility increased notably (Native Americans, 22.6% with parent facilities and 39.7% with satellite facilities; whites, 34.8% with parent facilities and 50.3% with satellite facilities; and Asians, 40.0% with parent facilities and 54.0% with satellite facilities), with less marked increases for Hispanic and black populations. Rural populations of all categories had dramatically low proportions living within 60 minutes of an NCI cancer center facility of any type (1.0%-6.6%). Approximately 14% of the population (n = 43,033,310) lived more than 180 minutes from a parent or satellite facility, and most of these individuals were Native Americans and/or rural residents (37% of Native Americans and 41.7% of isolated rural residents). Racial/ethnic and rural populations showed markedly improved geographic access to NCI cancer center care when satellite facilities were included. Cancer 2017;123:3305-11. © 2017 American Cancer Society. © 2017 American Cancer Society.

  16. Managing the visual effects of outer continental shelf and other petroleum-related coastal development

    Treesearch

    Philip A. Marcus; Ethan T. Smith

    1979-01-01

    Five petroleum-related facilities often sited in the coastal zone during development of Outer Continental oil and gas can change the visual appearance of coastal areas. These facilities are service bases, platform fabrication yards, marine terminals and associated storage facilities, oil and gas processing facilities, and liquified natural gas terminals. Examples of...

  17. Limited Service Availability, Readiness, and Use of Facility-Based Delivery Care in Haiti: A Study Linking Health Facility Data and Population Data

    PubMed Central

    Wang, Wenjuan; Winner, Michelle; Burgert-Brucker, Clara R

    2017-01-01

    Background: Understanding the barriers that women in Haiti face to giving birth at a health facility is important for improving coverage of facility delivery and reducing persistently high maternal mortality. We linked health facility survey data and population survey data to assess the role of the obstetric service environment in affecting women's use of facility delivery care. Methods: Data came from the 2012 Haiti Demographic and Health Survey (DHS) and the 2013 Haiti Service Provision Assessment (SPA) survey. DHS clusters and SPA facilities were linked with their geographic coordinate information. The final analysis sample from the DHS comprised 4,921 women who had a live birth in the 5 years preceding the survey. Service availability was measured with the number of facilities providing delivery services within a specified distance from the cluster (within 5 kilometers for urban areas and 10 kilometers for rural areas). We measured facility readiness to provide obstetric care using 37 indicators defined by the World Health Organization. Random-intercept logistic regressions were used to model the variation in individual use of facility-based delivery care and cluster-level service availability and readiness, adjusting for other factors. Results: Overall, 39% of women delivered their most recent birth at a health facility and 61% delivered at home, with disparities by residence (about 60% delivered at a health facility in urban areas vs. 24% in rural areas). About one-fifth (18%) of women in rural areas and one-tenth (12%) of women in nonmetropolitan urban areas lived in clusters where no facility offered delivery care within the specified distances, while nearly all women (99%) in the metropolitan area lived in clusters that had at least 2 such facilities. Urban clusters had better service readiness compared with rural clusters, with a wide range of variation in both areas. Regression models indicated that in both rural and nonmetropolitan urban areas availability of delivery services was significantly associated with women's greater likelihood of using facility-based delivery care after controlling for other covariates, while facilities' readiness to provide delivery services was also important in nonmetropolitan urban areas. Conclusion: Increasing physical access to delivery care should become a high priority in rural Haiti. In urban areas, where delivery services are more available than in rural areas, improving quality of care at facilities could potentially lead to increased coverage of facility delivery. PMID:28539502

  18. Toll facilities in the United States : bridges, roads, tunnels, ferries

    DOT National Transportation Integrated Search

    2005-06-01

    This report contains selected information on toll facilities in the United States. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 2005. /Abstract from report, p. xi/

  19. Toll Facilities in the United States : Bridges, Roads, Tunnels, Ferries

    DOT National Transportation Integrated Search

    2003-06-01

    This report contains selected information on toll facilities in the United States. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 2003. /Abstract from report, p. x/

  20. 75 FR 60409 - Diamond Sawblades and Parts Thereof From the People's Republic of China: Initiation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... facilities; (2) supplier relationships; (3) management; and (4) customer base.\\6\\ \\6\\ See Letter from Hebei...; and (4) customer base.\\8\\ Although no single factor will necessarily provide a dispositive indication... management, suppliers, customer base, and production facilities that the Department considers in its...

  1. The relationship of prenatal maternal depression or anxiety to maternal caregiving behavior and infant behavior self-regulation during infant heel lance: an ethological time-based study of behavior.

    PubMed

    Warnock, Fay F; Craig, Kenneth D; Bakeman, Roger; Castral, Thaila; Mirlashari, Jila

    2016-09-07

    Sensitive and responsive maternal caregiving behavior strengthens infant self-regulatory capacities (HL), but this regulatory role may be diminished in some mothers with second-trimester prenatal exposure to depression and/ or anxiety (MDA). This study examined maternal and infant behavior during infant heel lance (HL) when mothers had or did not have MDA. Ethological methods and micro-analytic approaches capable of distinguishing and comparing time-based patterning in maternal and infant behavior were used to clarify biological mechanisms, such as MDA, that may underlie observed behavior. Aims were to examine group differences in caregiving behavior between mothers with and without MDA 5 min Pre-HL and 5 min Post-H, and relationships between MDA, maternal caregiving behavior and infant pain behavior self-regulation, concurrently. At second trimester, mothers were assessed for symptoms of mild-severe depression or anxiety. Mothers whose scores exceeded predetermined cut-off scores on one or more of the mental health measures were allocated to the MDA-exposure group, those below to the non-MDA-exposure group. Reliable observers, blinded to MDA status and study phases, coded video records of the caregiving behavior of each study mother for the full duration of the 5 min Pre-HL and 5 min Post-HL study phases. Group differences and associations between mean measures of maternal mental health scores, time-based measures of maternal behavior, and time-based measures of infant pain behavior regulation (previously coded) were concurrently analyzed using comparative and correlational statistics. MDA-exposed mothers spent significantly more time not embracing, engaging or responding to infant cues than maternal controls Pre-HL and Post-HL. MDA was associated with atypical maternal caregiving behavior, which in turn was related to atypical infant pain behavior self-regulation during and after the HL. Our findings have implication for practice. We recommend inclusion of mothers with MDA and their infants in interventions that strengthen the early mother-infant interaction and mother's regulatory caregiving role. MDA and maternal caregiving behavior must be considered in future infant pain studies to examine if they confound effectiveness of mother driven caregiving interventions for neonatal pain. We highlight the importance of examining maternal mental health throughout the perinatal and postnatal trajectory, and particularly the newborn period.

  2. Hazardous waste: Siting of storage facility at Kelly Air Force Base, Texas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-01-01

    This report provides information on whether the hazardous waste storage facility at Kelly Air Force Base meets Resource Conservation and Recovery Act, state, and Air Force siting requirements; on whether the Air Force or the Defense Reutilization and Marketing Office selected the best site available to protect the public and to preserve good public relations with the community; on whether the Air Force, Kelly Air Force Base, or the Defense Logistics Agency adjusted siting standards as a result of the adverse publicity the hazardous waste facility has generated; and on whether Kelly Air Force Base is revising its hazardous wastemore » management organization so that it is similar to the organizations at Tinker and McClellan Air Force Bases.« less

  3. Strategic facility planning improves capital decision making.

    PubMed

    Reeve, J R

    2001-03-01

    A large, Midwestern IDS undertook a strategic facility-planning process to evaluate its facility portfolio and determine how best to allocate future investments in facility development. The IDS assembled a facility-planning team, which initiated the planning process with a market analysis to determine future market demands and identify service areas that warranted facility expansion. The team then analyzed each of the IDS's facilities from the perspective of uniform capacity measurements, highest and best use compared with needs, building condition and investment-worthiness, and facility growth and site development opportunities. Based on results of the analysis, the strategy adopted entailed, in part, shifting some space from inpatient care to ambulatory care services and demolishing and replacing the 11 percent of facilities deemed to be in the worst condition.

  4. Surrogate Plant Data Base : Volume 2. Appendix C : Facilities Planning Baseline Data

    DOT National Transportation Integrated Search

    1983-05-01

    This four volume report consists of a data base describing "surrogate" automobile and truck manufacturing plants developed as part of a methodology for evaluating capital investment requirements in new manufacturing facilities to build new fleets of ...

  5. Thermal Radiation Source Test Facility, Kirtland Air Force Base, New Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, W.F.

    This report describes the Thermal Radiation Source (TRS) Test Facility at Kirtland AF Base, New Mexico. It lists the instrumentation and equipment available for use by DOD and other government agencies studying the effects produced by nuclear weapons.

  6. 47 CFR 63.22 - Facilities-based international common carriers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... through post facto remedies, the International Bureau may impose temporary requirements on carriers.... 63.22 Section 63.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Supplements § 63.22 Facilities-based international common carriers. The following conditions apply to...

  7. 47 CFR 63.22 - Facilities-based international common carriers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... through post facto remedies, the International Bureau may impose temporary requirements on carriers.... 63.22 Section 63.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Supplements § 63.22 Facilities-based international common carriers. The following conditions apply to...

  8. 47 CFR 69.124 - Interconnection charge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES..., facilities-based rate elements in the future, from the part 69 transport revenue requirement, and dividing by... local exchange carrier anticipates will be reassigned to other, facilities-based rate elements in the...

  9. Microgravity research in NASA ground-based facilities

    NASA Technical Reports Server (NTRS)

    Lekan, Jack

    1989-01-01

    An overview of reduced gravity research performed in NASA ground-based facilities sponsored by the Microgravity Science and Applications Program of the NASA Office of Space Science and Applications is presented. A brief description and summary of the operations and capabilities of each of these facilities along with an overview of the historical usage of them is included. The goals and program elements of the Microgravity Science and Applications programs are described and the specific programs that utilize the low gravity facilities are identified. Results from two particular investigations in combustion (flame spread over solid fuels) and fluid physics (gas-liquid flows at microgravity conditions) are presented.

  10. The relationship between the availability of the supporting elements of pedestrian with pedestrian crossing facility usage based on user preferences (Case Study corridor of Sumbersari Street, Gajayana Street, MT. Haryono Street, Malang City)

    NASA Astrophysics Data System (ADS)

    Soetrisno, D. P.

    2017-06-01

    Pedestrian crossing facilities are effective enough to avoid pedestrians with vehicles, but its utilization is still quite low. It indicated that safety is not the only factor that influences a person to utilize the pedestrian crossing facilities. In addition, the availability of supporting elements of the pedestrian is still not quite attention, which is also became a factor that causes the pedestrians doesn’t utilize the pedestrian crossing facilities. Therefore, this research was structured to examine the relationship between the availability of the supporting elements of the pedestrian with pedestrian crossing facility usage based on user preferences. Data collection method used is primary survey consist of observation and the questionnaire. Sampling techniques used is purposive sampling with the number of respondents as many as 211 respondents by using questionnaire with ordinal scales to identify respondents’ consideration level of supporting elements pedestrian and crossing facility utilization factors. The survey is done on 15 crossing facilities area in 3 different locations with the same characteristics of land use in the form of higher education area (university area) and trades and services activities area. The analysis technique used is frequency distribution analysis in order to identify preference pedestrian on the availability of supporting elements of pedestrian and pedestrian crossing facility utilization factors, and chi square analysis is used to analyze the relationship between the availability of the supporting elements of the pedestrian with pedestrian crossing facility utilization. Based on the chi square analysis results with significance 5 % obtained the result that there are six supporting elements of pedestrian having correlation to the factors of pedestrian crossing facility utilization consist of the availability of sidewalk, pedestrian lights, Street Lighting Lamps, Pedestrian Crossing Markings Facilities, Sign Crossings Facilities, vegetation, and dustbin. So the result of this research can be considered for the government as main stakehoder especially the local government in preparing policy to provide supporting elements of pedestrian that should be on the area of pedestrian crossing facilities.

  11. Novel neutron sources at the Radiological Research Accelerator Facility

    PubMed Central

    Xu, Yanping; Garty, Guy; Marino, Stephen A.; Massey, Thomas N.; Randers-Pehrson, Gerhard; Johnson, Gary W.; Brenner, David J.

    2012-01-01

    Since the 1960s, the Radiological Research Accelerator Facility (RARAF) has been providing researchers in biology, chemistry and physics with advanced irradiation techniques, using charged particles, photons and neutrons. We are currently developing a unique facility at RARAF, to simulate neutron spectra from an improvised nuclear device (IND), based on calculations of the neutron spectrum at 1.5 km from the epicenter of the Hiroshima atom bomb. This is significantly different from a standard fission spectrum, because the spectrum changes as the neutrons are transported through air, and is dominated by neutron energies between 0.05 and 8 MeV. This facility will be based on a mixed proton/deuteron beam impinging on a thick beryllium target. A second, novel facility under development is our new neutron microbeam. The neutron microbeam will, for the first time, provide a kinematically collimated neutron beam, 10–20 micron in diameter. This facility is based on a Proton Microbeam, impinging on a thin lithium target near the threshold of the 7Li(p,n)7Be reaction. This novel neutron microbeam will enable studies of neutron damage to small targets, such as single cells, individual organs within small animals or microelectronic components. PMID:22545061

  12. Novel neutron sources at the Radiological Research Accelerator Facility.

    PubMed

    Xu, Yanping; Garty, Guy; Marino, Stephen A; Massey, Thomas N; Randers-Pehrson, Gerhard; Johnson, Gary W; Brenner, David J

    2012-03-16

    Since the 1960s, the Radiological Research Accelerator Facility (RARAF) has been providing researchers in biology, chemistry and physics with advanced irradiation techniques, using charged particles, photons and neutrons.We are currently developing a unique facility at RARAF, to simulate neutron spectra from an improvised nuclear device (IND), based on calculations of the neutron spectrum at 1.5 km from the epicenter of the Hiroshima atom bomb. This is significantly different from a standard fission spectrum, because the spectrum changes as the neutrons are transported through air, and is dominated by neutron energies between 0.05 and 8 MeV. This facility will be based on a mixed proton/deuteron beam impinging on a thick beryllium target.A second, novel facility under development is our new neutron microbeam. The neutron microbeam will, for the first time, provide a kinematically collimated neutron beam, 10-20 micron in diameter. This facility is based on a Proton Microbeam, impinging on a thin lithium target near the threshold of the (7)Li(p,n)(7)Be reaction. This novel neutron microbeam will enable studies of neutron damage to small targets, such as single cells, individual organs within small animals or microelectronic components.

  13. Novel neutron sources at the Radiological Research Accelerator Facility

    DOE PAGES

    Xu, Yanping; Garty, G.; Marino, S. A.; ...

    2012-03-16

    Since the 1960s, the Radiological Research Accelerator Facility (RARAF) has been providing researchers in biology, chemistry and physics with advanced irradiation techniques, using charged particles, photons and neutrons. We are currently developing a unique facility at RARAF, to simulate neutron spectra from an improvised nuclear device (IND), based on calculations of the neutron spectrum at 1.5 km from the epicenter of the Hiroshima atom bomb. This is significantly different from a standard fission spectrum, because the spectrum changes as the neutrons are transported through air, and is dominated by neutron energies between 0.05 and 8 MeV. This facility will bemore » based on a mixed proton/deuteron beam impinging on a thick beryllium target. A second, novel facility under development is our new neutron microbeam. The neutron microbeam will, for the first time, provide a kinematically collimated neutron beam, 10-20 micron in diameter. This facility is based on a proton microbeam, impinging on a thin lithium target near the threshold of the Li-7(p,n)Be-7 reaction. Lastly, this novel neutron microbeam will enable studies of neutron damage to small targets, such as single cells, individual organs within small animals or microelectronic components.« less

  14. Reduction of Neonatal Mortality Requires Strengthening of the Health System: A Situational Analysis of Neonatal Care Services in Ballabgarh.

    PubMed

    Gosain, Mudita; Goel, Akhil D; Kharya, Pradeep; Agarwal, Ramesh; Amarchand, Ritvik; Rai, Sanjay K; Kapoor, Suresh; Paul, Vinod K; Krishnan, Anand

    2017-10-01

    Planning a comprehensive program addressing neonatal mortality will require a detailed situational analysis of available neonatal-specific health infrastructure. We identified facilities providing essential and sick neonatal care (ENC, SNC) by a snowballing technique in Ballabgarh Block. These were assessed for infrastructure, human resource and equipment along with self-rated competency of the staff and compared with facility-based or population-based norms. A total of 35 facilities providing ENC and 10 facilities for SNC were identified. ENC services were largely in the public-sector domain (68.5% of births) and were well distributed in the block. SNC burden was largely being borne by the private sector (66% of admissions), which was urban-based. The private sector and nurses reported lower competency especially for SNC. Only 53.9% of government facilities and 17.5% of private facilities had a fully equipped newborn care corner. Serious efforts to reduce neonatal mortality would require major capacity strengthening of the health system, including that of the private sector. © The Author [2017]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  15. Novel neutron sources at the Radiological Research Accelerator Facility

    NASA Astrophysics Data System (ADS)

    Xu, Y.; Garty, G.; Marino, S. A.; Massey, T. N.; Randers-Pehrson, G.; Johnson, G. W.; Brenner, D. J.

    2012-03-01

    Since the 1960s, the Radiological Research Accelerator Facility (RARAF) has been providing researchers in biology, chemistry and physics with advanced irradiation techniques, using charged particles, photons and neutrons. We are currently developing a unique facility at RARAF, to simulate neutron spectra from an improvised nuclear device (IND), based on calculations of the neutron spectrum at 1.5 km from the epicenter of the Hiroshima atom bomb. This is significantly different from a standard fission spectrum, because the spectrum changes as the neutrons are transported through air, and is dominated by neutron energies between 0.05 and 8 MeV. This facility will be based on a mixed proton/deuteron beam impinging on a thick beryllium target. A second, novel facility under development is our new neutron microbeam. The neutron microbeam will, for the first time, provide a kinematically collimated neutron beam, 10-20 micron in diameter. This facility is based on a proton microbeam, impinging on a thin lithium target near the threshold of the 7Li(p,n)7Be reaction. This novel neutron microbeam will enable studies of neutron damage to small targets, such as single cells, individual organs within small animals or microelectronic components.

  16. [The development of the system of medical rehabilitation based at the Russian health resort facilities: investment prospects].

    PubMed

    Povazhnaya, E L; Gusakova, E V; Moiseenko, S V

    2018-05-21

    The present work is devoted to the prospects for attracting investments for the maintenance and development of the medical rehabilitation practices based at the Russian health resort facilities. The article describes the prerequisites for the enhancement of the investment attractiveness of the development of the system of medical rehabilitation in the said institutions including the formulation and strengthening of the legal and regulatory framework, the capacity for the organization of the second and third stages of medical rehabilitation in the existing spa and health resort facilities, the attraction of the funds of compulsory medical insurance as an additional source of the financial support. The main legal documents regulating the organization and provision of medical rehabilitation based at the spa and health resort facilities are presented. The results of the implementation of the investment concept of the development of medical rehabilitation in the framework of the system of health resort treatment as exemplified by the experience of JSC «The group of companies «Medsi» are discussed. It is shown that the development of medical rehabilitation based at the spa and health resort facilities greatly contributes to the significant expansion of the potential customer base and promotes the further growth of business scale.

  17. Availability of emergency obstetric care (EmOC) among public and private health facilities in rural northwest Bangladesh.

    PubMed

    Sikder, Shegufta S; Labrique, Alain B; Ali, Hasmot; Hanif, Abu A M; Klemm, Rolf D W; Mehra, Sucheta; West, Keith P; Christian, Parul

    2015-01-31

    Although safe motherhood strategies recommend that women seek timely care from health facilities for obstetric complications, few studies have described facility availability of emergency obstetric care (EmOC). We sought to describe and compare availability and readiness to provide EmOC among public and private health facilities commonly visited for pregnancy-related complications in two districts of northwest Bangladesh. We also described aspects of financial and geographic access to healthcare and key constraints to EmOC provision. Using data from a large population-based community trial, we identified and surveyed the 14 health facilities (7 public, 7 private) most frequently visited for obstetric complications and near misses as reported by women. Availability of EmOC was based on provision of medical services, assessed through clinician interviews and record review. Levels of EmOC availability were defined as basic or comprehensive. Readiness for EmOC provision was based on scores in four categories: staffing, equipment, laboratory capacity, and medicines. Readiness scores were calculated using unweighted averages. Costs of C-section procedures and geographic locations of facilities were described. Textual analysis was used to identify key constraints. The seven surveyed private facilities offered comprehensive EmOC compared to four of the seven public facilities. With 100% representing full readiness, mean EmOC readiness was 81% (range: 63%-91%) among surveyed private facilities compared to 67% (range: 48%-91%) in public facilities (p = 0.040). Surveyed public clinics had low scores on staffing and laboratory capacity (69%; 50%). The mean cost of the C-section procedure in private clinics was $77 (standard deviation: $16) and free in public facilities. The public sub-district facilities were the only facilities located in rural areas, with none providing comprehensive EmOC. Shortages in specialized staff were listed as the main barrier to EmOC provision in public facilities. Although EmOC availability and readiness was higher among the surveyed seven most commonly visited private clinics, public facilities appeared to be more affordable for C-section and more geographically accessible. Strategies to retain anesthesiologists and surgeons, such as non-financial incentives, are needed to improve EmOC provision in the public sector. Centralized blood banks are recommended to streamline safe blood acquisition for obstetric surgeries.

  18. Panorama, section 2 of 3, note the Operations Building (Facility ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Panorama, section 2 of 3, note the Operations Building (Facility 294) in the center of facility, view facing west - U.S. Naval Base, Pearl Harbor, Naval Radio Station, AF/FRD-10 Circularly Disposed Antenna Array, Wahiawa, Honolulu County, HI

  19. Medicare: Comparison of Catastropic Health Insurance Proposals--an Update.

    DTIC Science & Technology

    1987-10-01

    Accounting Office ICF intermediate care facility SNF skilled nursing facility VA Veterans Administration d4 ....... ’. - --- MEDICARE: COMPARISON OF...optional woe services, such as home and community-based services; services in an intermediate care facility (ICF); and prescribed drugs, dentures

  20. Medicare: Comparison of Catastrophic Health Insurance Proposals.

    DTIC Science & Technology

    1987-06-01

    GAO General Accounting Office ICF intermediate care facility SNF skilled nursing facility VA Veterans Administration -4 MEDICARE: COMPARISON OF...community-based services; services in an intermediate care facility (ICF); and prescribed drugs, dentures, and eyeglasses. In recent years, the number of

  1. Women's Preferences for Place of Delivery in Rural Tanzania: A Population-Based Discrete Choice Experiment

    PubMed Central

    Paczkowski, Magdalena; Mbaruku, Godfrey; de Pinho, Helen; Galea, Sandro

    2009-01-01

    Objectives. We fielded a population-based discrete choice experiment (DCE) in rural western Tanzania, where only one third of women deliver children in a health facility, to evaluate health-system factors that influence women's delivery decisions. Methods. Women were shown choice cards that described 2 hypothetical health centers by means of 6 attributes (distance, cost, type of provider, attitude of provider, drugs and equipment, free transport). The women were then asked to indicate which of the 2 facilities they would prefer to use for a future delivery. We used a hierarchical Bayes procedure to estimate individual and mean utility parameters. Results. A total of 1203 women completed the DCE. The model showed good predictive validity for actual facility choice. The most important facility attributes were a respectful provider attitude and availability of drugs and medical equipment. Policy simulations suggested that if these attributes were improved at existing facilities, the proportion of women preferring facility delivery would rise from 43% to 88%. Conclusions. In regions in which attended delivery rates are low despite availability of primary care facilities, policy experiments should test the effect of targeted quality improvements on facility use. PMID:19608959

  2. 12 CFR 7.5006 - Data processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... banking functions. A national bank may produce, market, or sell software that performs services or... services, facilities (including equipment, technology, and personnel), data bases, advice and access to such services, facilities, data bases and advice, for itself and for others, where the data is banking...

  3. EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet

    EPA Pesticide Factsheets

    This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz

  4. EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet Download

    EPA Pesticide Factsheets

    This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers

  5. EPA Facility Registry Service (FRS): Facility Interests Dataset Download

    EPA Pesticide Factsheets

    This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers

  6. EPA Facility Registry Service (FRS): Facility Interests Dataset

    EPA Pesticide Factsheets

    This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in the FRS individual feature layers. The layers comprise the FRS major program databases, including:Assessment Cleanup and Redevelopment Exchange System (ACRES) : brownfields sites ; Air Facility System (AFS) : stationary sources of air pollution ; Air Quality System (AQS) : ambient air pollution data from monitoring stations; Bureau of Indian Affairs (BIA) : schools data on Indian land; Base Realignment and Closure (BRAC) facilities; Clean Air Markets Division Business System (CAMDBS) : market-based air pollution control programs; Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) : hazardous waste sites; Integrated Compliance Information System (ICIS) : integrated enforcement and compliance information; National Compliance Database (NCDB) : Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Toxic Substances Control Act (TSCA); National Pollutant Discharge Elimination System (NPDES) module of ICIS : NPDES surface water permits; Radiation Information Database (RADINFO) : radiation and radioactivity facilities; RACT/BACT/LAER Clearinghouse (RBLC) : best available air pollution technology requirements; Resource Conservation and Recovery Act Information System (RCRAInfo) : tracks generators, transporters, treaters, storers, and disposers of haz

  7. Toll facilities in the United States : bridges, roads, tunnels, ferries

    DOT National Transportation Integrated Search

    2007-12-01

    This report contains selected information on toll facilities in the United States that has been provided to FHWA by the States and/or various toll authorities. The information is based on a survey of facilities in operation, financed, or under constr...

  8. Preliminary definition of a lunar landing and launch facility (Complex 39L)

    NASA Technical Reports Server (NTRS)

    Matthews, H. Dennis; Jenson, Eric B.; Linsley, Jerald N.

    1992-01-01

    A preliminary definition of a lunar landing and launch facility has been formulated. A permanently manned lunar base and a baseline lunar module are assumed. The major features of the facility are specified and major design areas are described.

  9. Use of a Balanced Scorecard in strengthening health systems in developing countries: an analysis based on nationally representative Bangladesh Health Facility Survey.

    PubMed

    Khan, M Mahmud; Hotchkiss, David R; Dmytraczenko, Tania; Zunaid Ahsan, Karar

    2013-01-01

    This paper illustrates the importance of collecting facility-based data through regular surveys to supplement the administrative data, especially for developing countries of the world. In Bangladesh, measures based on facility survey indicate that only 70% of very basic medical instruments and 35% of essential drugs were available in health facilities. Less than 2% of officially designated obstetric care facilities actually had required drugs, injections and personnel on-site. Majority of (80%) referral hospitals at the district level were not ready to provide comprehensive emergency obstetric care. Even though the Management Information System reports availability of diagnostic machines in all district-level and sub-district-level facilities, it fails to indicate that 50% of these machines are not functional. In terms of human resources, both physicians and nurses are in short supply at all levels of the healthcare system. The physician-nurse ratio also remains lower than the desirable level of 3.0. Overall job satisfaction index was less than 50 for physicians and 66 for nurses. Patient satisfaction score, however, was high (86) despite the fact that process indicators of service quality were poor. Facility surveys can help strengthen not only the management decision-making process but also the quality of administrative data. Copyright © 2012 John Wiley & Sons, Ltd.

  10. Impact of facility size and profit status on intermediate outcomes in chronic dialysis patients.

    PubMed

    Frankenfield, D L; Sugarman, J R; Presley, R J; Helgerson, S D; Rocco, M V

    2000-08-01

    Little information is available regarding the influence of dialysis facility size or profit status on intermediate outcomes in chronic dialysis patients. We have combined data from the Health Care Financing Administration (HCFA) Core Indicators Project; the end-stage renal disease (ESRD) facility survey; and the HCFA On-Line Survey, Certification, and Reporting System to analyze trends in this area. For hemodialysis patients, larger facilities were more likely than smaller facilities to perform dialysis on patients who were younger than 65 years of age, black, or undergoing dialysis 2 years or more (P < 0.001). Nonprofit facilities were more likely to perform dialysis on patients with diabetes mellitus as a cause of ESRD and less likely to perform dialysis on patients with hypertension as a cause of ESRD compared with for-profit units (P < 0.05). By multivariate analysis, larger facility size was modestly associated with a greater Kt/V value and urea reduction ratio, but not with hematocrit or serum albumin values. Facility profit status was not associated with these intermediate outcomes. For peritoneal dialysis patients, there were no significant differences in patient demographics based on facility size. More patients in nonprofit units had been undergoing dialysis 2 or more years than patients in for-profit units (P < 0.05). By univariate analysis, patients in larger facilities were more likely to have an adequacy measure performed than patients from smaller facilities (P < 0.05). There were few substantial differences in intermediate outcomes in chronic dialysis patients based on facility size or profit status.

  11. Optically-based Sensor System for Critical Nuclear Facilities Post-Event Seismic Structural Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCallen, David; Petrone, Floriana; Buckle, Ian

    The U.S. Department of Energy (DOE) has ownership and operational responsibility for a large enterprise of nuclear facilities that provide essential functions to DOE missions ranging from national security to discovery science and energy research. These facilities support a number of DOE programs and offices including the National Nuclear Security Administration, Office of Science, and Office of Environmental Management. With many unique and “one of a kind” functions, these facilities represent a tremendous national investment, and assuring their safety and integrity is fundamental to the success of a breadth of DOE programs. Many DOE critical facilities are located in regionsmore » with significant natural phenomenon hazards including major earthquakes and DOE has been a leader in developing standards for the seismic analysis of nuclear facilities. Attaining and sustaining excellence in nuclear facility design and management must be a core competency of the DOE. An important part of nuclear facility management is the ability to monitor facilities and rapidly assess the response and integrity of the facilities after any major upset event. Experience in the western U.S. has shown that understanding facility integrity after a major earthquake is a significant challenge which, lacking key data, can require extensive effort and significant time. In the work described in the attached report, a transformational approach to earthquake monitoring of facilities is described and demonstrated. An entirely new type of optically-based sensor that can directly and accurately measure the earthquake-induced deformations of a critical facility has been developed and tested. This report summarizes large-scale shake table testing of the sensor concept on a representative steel frame building structure, and provides quantitative data on the accuracy of the sensor measurements.« less

  12. The use of an automated flight test management system in the development of a rapid-prototyping flight research facility

    NASA Technical Reports Server (NTRS)

    Duke, Eugene L.; Hewett, Marle D.; Brumbaugh, Randal W.; Tartt, David M.; Antoniewicz, Robert F.; Agarwal, Arvind K.

    1988-01-01

    An automated flight test management system (ATMS) and its use to develop a rapid-prototyping flight research facility for artificial intelligence (AI) based flight systems concepts are described. The ATMS provides a flight test engineer with a set of tools that assist in flight planning and simulation. This system will be capable of controlling an aircraft during the flight test by performing closed-loop guidance functions, range management, and maneuver-quality monitoring. The rapid-prototyping flight research facility is being developed at the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) to provide early flight assessment of emerging AI technology. The facility is being developed as one element of the aircraft automation program which focuses on the qualification and validation of embedded real-time AI-based systems.

  13. Major Range and Test Facility Base Summary of Capabilities.

    DTIC Science & Technology

    1983-06-01

    TEST CHART NATIONAL BUREAU OF STANDARDS 1963 A 3,i 4, S °.I i L -. ~ . % o,. ° . - ° . - . .I ¢ PHOTOGRAPH THIS SHEET LEVEL INVENTORY DOCUMENT...NUMBER DOD 3200.11-D 4. TTLE(~dS..tt~t@) S TYPE Of REPORT a PERIO’ COVERED Major Range and Test Facility Base Summary Reference Maerial of Capabilities...Electronic Warfare, Command, Control Communications and Intelligence (C31) Surveillance, Jammers, Radar, Test Facility ZG5 ABETW ACT f~ a "Afie Afr- s 444 eF~f

  14. The development of an automated flight test management system for flight test planning and monitoring

    NASA Technical Reports Server (NTRS)

    Hewett, Marle D.; Tartt, David M.; Duke, Eugene L.; Antoniewicz, Robert F.; Brumbaugh, Randal W.

    1988-01-01

    The development of an automated flight test management system (ATMS) as a component of a rapid-prototyping flight research facility for AI-based flight systems concepts is described. The rapid-prototyping facility includes real-time high-fidelity simulators, numeric and symbolic processors, and high-performance research aircraft modified to accept commands for a ground-based remotely augmented vehicle facility. The flight system configuration of the ATMS includes three computers: the TI explorer LX and two GOULD SEL 32/27s.

  15. Ecologically Based Interventions in Residential and School Facilities: Theory or Practice?

    ERIC Educational Resources Information Center

    Termini, Ann Marie

    1991-01-01

    Illustrates some important differences between interdisciplinary and ecological perspectives on meeting the needs of adolescents experiencing emotional difficulties. Highlights use of ecosystemic models in residential and school facilities and enumerates areas where ecologically based changes might be appropriate. Outlines operational guidelines…

  16. SOLVENT-BASED TO WATERBASED ADHESIVE-COATED SUBSTRATE RETROFIT - VOLUME III: LABEL MANUFACTURING CASE STUDY: NASHUA CORPORATION

    EPA Science Inventory

    This volume discusses Nashua Corporation's Omaha facility, a label and label stock manufacturing facility that no longer uses solvent-based adhesives. Information obtained includes issues related to the technical, economic, and environmental barriers and opportunities associated ...

  17. Toll facilities in the United States : Bridges, Roads, Tunnels, Ferries

    DOT National Transportation Integrated Search

    1993-02-01

    Selected information on toll facilities in the United States open to the public are contained in this report. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 1993. The information is p...

  18. Toll facilities in the United States : bridges, roads, tunnels, ferries

    DOT National Transportation Integrated Search

    1995-02-01

    This report contains selected information on toll facilities in the United States. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 1995, and is presented in four tables. Table T-1 cont...

  19. Toll Facilities in the United States : Bridges, Roads, Tunnels, Ferries

    DOT National Transportation Integrated Search

    1999-02-01

    This report contains selected information on toll facilities in the United States. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 1999, and is presented in six tables. Table T-1 conta...

  20. 45 CFR 1304.53 - Facilities, materials, and equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... (a) Head Start physical environment and facilities. (1) Grantee and delegate agencies must provide a physical environment and facilities conducive to learning and reflective of the different stages of... delegate agencies must provide a center-based environment free of toxins, such as cigarette smoke, lead...

  1. Sabbatical Report: Results of a Survey of Library Microforms Facilities.

    ERIC Educational Resources Information Center

    McIntosh, Melinda C.

    1987-01-01

    Highlights findings on the status of academic library microforms facilities in the United States and Canada based on visits to 11 libraries. Topics covered include administration, personnel, collection access and storage, classification, acquisition, circulation, indexes, hours, facilities, signage, equipment, photocopying, cleanliness, vandalism,…

  2. Observation of Neutron Skyshine from an Accelerator Based Neutron Source

    NASA Astrophysics Data System (ADS)

    Franklyn, C. B.

    2011-12-01

    A key feature of neutron based interrogation systems is the need for adequate provision of shielding around the facility. Accelerator facilities adapted for fast neutron generation are not necessarily suitably equipped to ensure complete containment of the vast quantity of neutrons generated, typically >1011 nṡs-1. Simulating the neutron leakage from a facility is not a simple exercise since the energy and directional distribution can only be approximated. Although adequate horizontal, planar shielding provision is made for a neutron generator facility, it is sometimes the case that vertical shielding is minimized, due to structural and economic constraints. It is further justified by assuming the atmosphere above a facility functions as an adequate radiation shield. It has become apparent that multiple neutron scattering within the atmosphere can result in a measurable dose of neutrons reaching ground level some distance from a facility, an effect commonly known as skyshine. This paper describes a neutron detection system developed to monitor neutrons detected several hundred metres from a neutron source due to the effect of skyshine.

  3. Seismic assessment of Technical Area V (TA-V).

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Medrano, Carlos S.

    The Technical Area V (TA-V) Seismic Assessment Report was commissioned as part of Sandia National Laboratories (SNL) Self Assessment Requirement per DOE O 414.1, Quality Assurance, for seismic impact on existing facilities at Technical Area-V (TA-V). SNL TA-V facilities are located on an existing Uniform Building Code (UBC) Seismic Zone IIB Site within the physical boundary of the Kirtland Air Force Base (KAFB). The document delineates a summary of the existing facilities with their safety-significant structure, system and components, identifies DOE Guidance, conceptual framework, past assessments and the present Geological and Seismic conditions. Building upon the past information and themore » evolution of the new seismic design criteria, the document discusses the potential impact of the new standards and provides recommendations based upon the current International Building Code (IBC) per DOE O 420.1B, Facility Safety and DOE G 420.1-2, Guide for the Mitigation of Natural Phenomena Hazards for DOE Nuclear Facilities and Non-Nuclear Facilities.« less

  4. Using business intelligence for efficient inter-facility patient transfer.

    PubMed

    Haque, Waqar; Derksen, Beth Ann; Calado, Devin; Foster, Lee

    2015-01-01

    In the context of inter-facility patient transfer, a transfer operator must be able to objectively identify a destination which meets the needs of a patient, while keeping in mind each facility's limitations. We propose a solution which uses Business Intelligence (BI) techniques to analyze data related to healthcare infrastructure and services, and provides a web based system to identify optimal destination(s). The proposed inter-facility transfer system uses a single data warehouse with an Online Analytical Processing (OLAP) cube built on top that supplies analytical data to multiple reports embedded in web pages. The data visualization tool includes map based navigation of the health authority as well as an interactive filtering mechanism which finds facilities meeting the selected criteria. The data visualization is backed by an intuitive data entry web form which safely constrains the data, ensuring consistency and a single version of truth. The overall time required to identify the destination for inter-facility transfers is reduced from hours to a few minutes with this interactive solution.

  5. The Role of Distance and Quality on Facility Selection for Maternal and Child Health Services in Urban Kenya.

    PubMed

    Escamilla, Veronica; Calhoun, Lisa; Winston, Jennifer; Speizer, Ilene S

    2018-02-01

    Universal access to health care requires service availability and accessibility for those most in need of maternal and child health services. Women often bypass facilities closest to home due to poor quality. Few studies have directly linked individuals to facilities where they sought maternal and child health services and examined the role of distance and quality on this facility choice. Using endline data from a longitudinal survey from a sample of women in five cities in Kenya, we examine the role of distance and quality on facility selection for women using delivery, facility-based contraceptives, and child health services. A survey of public and private facilities offering reproductive health services was also conducted. Distances were measured between household cluster location and both the nearest facility and facility where women sought care. A quality index score representing facility infrastructure, staff, and supply characteristics was assigned to each facility. We use descriptive statistics to compare distance and quality between the nearest available facility and visited facility among women who bypassed the nearest facility. Facility distance and quality comparisons were also stratified by poverty status. Logistic regression models were used to measure associations between the quality and distance to the nearest facility and bypassing for each outcome. The majority of women bypassed the nearest facility regardless of service sought. Women bypassing for delivery traveled the furthest and had the fewest facility options near their residential cluster. Poor women bypassing for delivery traveled 4.5 km further than non-poor women. Among women who bypassed, two thirds seeking delivery and approximately 46% seeking facility-based contraception or child health services bypassed to a public hospital. Both poor and non-poor women bypassed to higher quality facilities. Our findings suggest that women in five cities in Kenya prefer public hospitals and are willing to travel further to obtain services at public hospitals, possibly related to free service availability. Over time, it will be important to examine service quality and availability in public sector facilities with reduced or eliminated user fees, and whether it lends itself to a continuum of care where women can visit one facility for multiple services reducing travel burden.

  6. A health maintenance facility for space station freedom

    NASA Technical Reports Server (NTRS)

    Billica, R. D.; Doarn, C. R.

    1991-01-01

    We describe a health care facility to be built and used on an orbiting space station in low Earth orbit. This facility, called the health maintenance facility, is based on and modeled after isolated terrestrial medical facilities. It will provide a phased approach to health care for the crews of Space Station Freedom. This paper presents the capabilities of the health maintenance facility. As Freedom is constructed over the next decade there will be an increase in activities, both construction and scientific. The health maintenance facility will evolve with this process until it is a mature, complete, stand-alone health care facility that establishes a foundation to support interplanetary travel. As our experience in space continues to grow so will the commitment to providing health care.

  7. Biomineralization of endolithic microbes in rocks from the McMurdo Dry Valleys of Antarctica: implications for microbial fossil formation and their detection.

    PubMed

    Wierzchos, Jacek; Sancho, Leopoldo García; Ascaso, Carmen

    2005-04-01

    In some zones of Antarctica's cold and dry desert, the extinction of cryptoendolithic microorganisms leaves behind inorganic traces of microbial life. In this paper, we examine the transition from live microorganisms, through their decay, to microbial fossils using in situ microscopy (transmission electron microscopy, scanning electron microscopy in back-scattered electron mode) and microanalytical (energy dispersive X-ray spectroscopy) techniques. Our results demonstrate that, after their death, endolithic microorganisms inhabiting Commonwealth Glacier sandstone from the Antarctica McMurdo Dry Valleys become mineralized. In some cases, epicellular deposition of minerals and/or simply filling up of empty moulds by minerals leads to the formation of cell-shaped structures that may be considered biomarkers. The continuous deposition of allochthonous clay minerals and sulfate-rich salts fills the sandstone pores. This process can give rise to microbial fossils with distinguishable cell wall structures. Often, fossilized cell interiors were of a different chemical composition to the mineralized cell walls. We propose that the microbial fossil formation observed was induced by mineral precipitation resulting from inorganic processes occurring after the death of cryptoendolithic microorganisms. Nevertheless, it must have been the organic template that provoked the diffusion of mineral elements and gave rise to their characteristic distribution pattern inside the fossilized cells.

  8. Current Nucleic Acid Extraction Methods and Their Implications to Point-of-Care Diagnostics.

    PubMed

    Ali, Nasir; Rampazzo, Rita de Cássia Pontello; Costa, Alexandre Dias Tavares; Krieger, Marco Aurelio

    2017-01-01

    Nucleic acid extraction (NAE) plays a vital role in molecular biology as the primary step for many downstream applications. Many modifications have been introduced to the original 1869 method. Modern processes are categorized into chemical or mechanical, each with peculiarities that influence their use, especially in point-of-care diagnostics (POC-Dx). POC-Dx is a new approach aiming to replace sophisticated analytical machinery with microanalytical systems, able to be used near the patient, at the point of care or point of need . Although notable efforts have been made, a simple and effective extraction method is still a major challenge for widespread use of POC-Dx. In this review, we dissected the working principle of each of the most common NAE methods, overviewing their advantages and disadvantages, as well their potential for integration in POC-Dx systems. At present, it seems difficult, if not impossible, to establish a procedure which can be universally applied to POC-Dx. We also discuss the effects of the NAE chemicals upon the main plastic polymers used to mass produce POC-Dx systems. We end our review discussing the limitations and challenges that should guide the quest for an efficient extraction method that can be integrated in a POC-Dx system.

  9. Incorporation of Metals into Calcite in a Deep Anoxic Granite Aquifer.

    PubMed

    Drake, Henrik; Mathurin, Frédéric A; Zack, Thomas; Schäfer, Thorsten; Roberts, Nick Mw; Whitehouse, Martin; Karlsson, Andreas; Broman, Curt; Åström, Mats E

    2018-01-16

    Understanding metal scavenging by calcite in deep aquifers in granite is of importance for deciphering and modeling hydrochemical fluctuations and water-rock interaction in the upper crust and for retention mechanisms associated with underground repositories for toxic wastes. Metal scavenging into calcite has generally been established in the laboratory or in natural environments that cannot be unreservedly applied to conditions in deep crystalline rocks, an environment of broad interest for nuclear waste repositories. Here, we report a microanalytical study of calcite precipitated over a period of 17 years from anoxic, low-temperature (14 °C), neutral (pH: 7.4-7.7), and brackish (Cl: 1700-7100 mg/L) groundwater flowing in fractures at >400 m depth in granite rock. This enabled assessment of the trace metal uptake by calcite under these deep-seated conditions. Aquatic speciation modeling was carried out to assess influence of metal complexation on the partitioning into calcite. The resulting environment-specific partition coefficients were for several divalent ions in line with values obtained in controlled laboratory experiments, whereas for several other ions they differed substantially. High absolute uptake of rare earth elements and U(IV) suggests that coprecipitation into calcite can be an important sink for these metals and analogousactinides in the vicinity of geological repositories.

  10. Transmission electron microscopy, fluorescence microscopy, and confocal raman microscopic analysis of ultrastructural and compositional heterogeneity of Cornus alba L. wood cell wall.

    PubMed

    Ma, Jianfeng; Ji, Zhe; Zhou, Xia; Zhang, Zhiheng; Xu, Feng

    2013-02-01

    Transmission electron microscopy (TEM), fluorescence microscopy, and confocal Raman microscopy can be used to characterize ultrastructural and compositional heterogeneity of plant cell walls. In this study, TEM observations revealed the ultrastructural characterization of Cornus alba L. fiber, vessel, axial parenchyma, ray parenchyma, and pit membrane between cells, notably with the ray parenchyma consisting of two well-defined layers. Fluorescence microscopy evidenced that cell corner middle lamella was more lignified than adjacent compound middle lamella and secondary wall with variation in lignification level from cell to cell. In situ Raman images showed that the inhomogeneity in cell wall components (cellulose and lignin) among different cells and within morphologically distinct cell wall layers. As the significant precursors of lignin biosynthesis, the pattern of coniferyl alcohol and aldehyde (joint abbreviation Lignin-CAA for both structures) distribution in fiber cell wall was also identified by Raman images, with higher concentration occurring in the fiber secondary wall where there was the highest cellulose concentration. Moreover, noteworthy was the observation that higher concentration of lignin and very minor amounts of cellulose were visualized in the pit membrane areas. These complementary microanalytical methods provide more accurate and complete information with regard to ultrastructural and compositional characterization of plant cell walls.

  11. The influence of maternal language responsiveness on the expressive speech production of children with autism spectrum disorders: a microanalysis of mother-child play interactions.

    PubMed

    Walton, Katherine M; Ingersoll, Brooke R

    2015-05-01

    Adult responsiveness is related to language development both in young typically developing children and in children with autism spectrum disorders, such that parents who use more responsive language with their children have children who develop better language skills over time. This study used a micro-analytic technique to examine how two facets of maternal utterances, relationship to child focus of attention and degree of demandingness, influenced the immediate use of appropriate expressive language of preschool-aged children with autism spectrum disorders (n = 28) and toddlers with typical development (n = 16) within a naturalistic mother-child play session. Mothers' use of follow-in demanding language was most likely to elicit appropriate expressive speech in both children with autism spectrum disorders and children with typical development. For children with autism spectrum disorders, but not children with typical development, mothers' use of orienting cues conferred an additional benefit for expressive speech production. These findings are consistent with the naturalistic behavioral intervention philosophy and suggest that following a child's lead while prompting for language is likely to elicit speech production in children with autism spectrum disorders and children with typical development. Furthermore, using orienting cues may help children with autism spectrum disorders to verbally respond. © The Author(s) 2014.

  12. Cesium distribution and phases in proxy experiments on the incineration of radioactively contaminated waste from the Fukushima area.

    PubMed

    Saffarzadeh, Amirhomayoun; Shimaoka, Takayuki; Kakuta, Yoshitada; Kawano, Takashi

    2014-10-01

    After the March 11, 2011 Tohoku earthquake and Fukushima I Nuclear Power Plant accident, incineration was initially adopted as an effective technique for the treatment of post-disaster wastes. Accordingly, considerable amounts of radioactively contaminated residues were immediately generated through incineration. The level of radioactivity associated with radiocesium in the incineration ash residues (bottom ash and fly ash) became significantly high (several thousand to 100,000 Bq/kg) as a result of this treatment. In order to understand the modes of occurrence of radiocesium, bottom ash products were synthesized through combusting of refuse-derived fuel (RDF) with stable Cs salts in a pilot incinerator. Microscopic and microanalytical (SEM-EDX) techniques were applied and the following Cs categories were identified: low and high concentrations in the matrix glass, low-level partitioning into some newly-formed silicate minerals, partitioning into metal-sulfide compounds, and occurring in newly-formed Cs-rich minerals. These categories that are essentially silicate-bound are the most dominant forms in large and medium size bottom ash particles. It is expected that these achievements provide solutions to the immobilization of radiocesium in the incineration ash products contaminated by Fukushima nuclear accident. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Nanostructure characterisation of flow-formed Cr-Mo-V steel using transmission Kikuchi diffraction technique.

    PubMed

    Birosca, S; Ding, R; Ooi, S; Buckingham, R; Coleman, C; Dicks, K

    2015-06-01

    Nowadays flow-forming has become a desired near net shape manufacturing method as it provides excellent mechanical properties with improved surface finish and significant manufacturing cost reduction. However, the material is subjected to excessive plastic deformation during flow-forming process, generating a very fine and complex microstructure. In addition, the intense dislocation density and residual stress that is generated in the component during processing makes the microstructure characterisation using conventional micro-analytical tools challenging. Thus, the microstructure/property relationship study in such a material is rather difficult. In the present study a flow-formed Cr-Mo-V steel nanostructure and crystallographic texture were characterised by means of Transmission Kikuchi Diffraction (TKD). Here, TKD is shown to be a powerful technique in revealing very fine martensite laths within an austenite matrix. Moreover, fine precipitates in the order of 20-70 nm on the martensite lath boundaries were clearly imaged and characterised. This greatly assisted in understanding the preferable site formation of the carbides in such a complex microstructure. The results showed that the actual TKD spatial resolution was in the range of 5-10 nm using 25 kV for flow-formed Cr-Mo-V steel. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Glimpses into the blind spot: Social interaction and autism.

    PubMed

    Bottema-Beutel, Kristen

    2017-07-01

    A primary feature of autism spectrum disorder (ASD) is marked difficulty in social interactions. Despite the centrality of social interaction differences to the clinical presentation of ASD, only a small portion of research in this field characterizes interaction in everyday social contexts. This theoretical paper reviews the growing corpus of interactional research on ASD, including discourse analysis (DA) and conversation analysis (CA) approaches. DA and CA are micro-analytic methods aimed at understanding the organizational structure of, and actions pursued within, social encounters. These methods are aligned with enactive theories of social interaction. The bulk of current ASD research construes social interaction as involving isolated individuals who represent and/or theorize about the minds of an interlocutor. Enactive approaches posit that achieving intersubjectivity does not require theories of other minds, but instead a propensity for coordinating social actions with others. Through the complementary lenses of enactivism and interactional research, I offer an account of autistic social interaction as involving differences in interactional coordination, interactional priorities, and the enactment of meaning across conversational turns. This characterization challenges the explanatory role of cognitive processes such as Theory of Mind, and points to new avenues for conceptualizing, measuring, and supporting social interaction. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. TCP is hardly resorbed and not osteoconductive in a non-loading calvarial model.

    PubMed

    Handschel, Jörg; Wiesmann, Hans Peter; Stratmann, Udo; Kleinheinz, Johannes; Meyer, Ulrich; Joos, Ulrich

    2002-04-01

    Tricalciumphosphate (TCP) has been used as a ceramic bone substitute material in the orthopedic field as well as in craniofacial surgery. Some controversies exist concerning the osteoconductive potential of this material in different implantation sites. This study was designed to evaluate the biological response of calvarial bone towards TCP granules under non-loading conditions to assess the potential of TCP as a biodegredable and osteoconductive bone substitue material for the cranial vault. Full-thickness non-critical size defects were made bilaterally in the calvaria of 21 adult Wistar rats. One side was filled by TCP granules, the contralateral side was left empty and used as a control. Animals were sacrified in defined time intervals up to 6 months. Bone regeneration was analyzed with special respect toward the micromorphological and microanalytical features of the material-bone interaction by electron microscopy and electron diffraction analysis. Histologic examination revealed no TCP degradation even after 6 months of implantation. In contrast, a nearly complete bone regeneration of control defects was found after 6 months. At all times TCP was surrounded by a thin fibrous layer without presence of osteoblasts and features of regular mineralization. As far as degradation and substitution are concerned, TCP is a less favourable material tinder conditions of non-loading.

  16. Chromium oxidation state mapping in human cells

    NASA Astrophysics Data System (ADS)

    Ortega, R.; Fayard, B.; Salomé, M.; Devès, G.; Susini, J.

    2003-03-01

    The widespread use of chromium in industrial applications such as chemical production of pigments, refractory brick production, tanning, metallurgy, electroplating, and combustion of fuels has lead to human occupational exposure and to its increased introduction into the environment. Hexavalent chromium compounds are established carcinogens but their mechanism of cell transformation is not known. Up to now, no microanalytical technique was sensitive enough to allow the observation of chromium distribution, and oxidation state identification, within isolated cells at carcinogenic concentrations. In this experiment, we used successfully the ID-21 X-ray microscope to map Cr(VI) and total Cr distributions in cells exposed in vitro to soluble, and insoluble, Cr(VI) compounds. Exposure to soluble compounds, weak carcinogens, resulted in a homogeneous intracellular distribution of Cr, confirming by in situ measurement that Cr is present in the cell nucleus. Cr(VI) was never detected in cells which suggests a mechanism of rapid intracellular reducticn. On the other hand, exposure to insoluble compounds, strong carcinogens, also resulted in a homogeneous distribution of reduced forms of Cr in cells, and their nucleus. However, in this case, Cr(VI)-rich structures were observed into the cells suggesting that carcinogenicity is enhanced when oxidation reactions due to Cr(VI) chronic exposure are associated to Cr-DNA alterations.

  17. Prospects for Practical Laser Ablation U/Pb and (U-Th)/He Double-Dating (LADD) of Detrital Apatite

    NASA Astrophysics Data System (ADS)

    Horne, A.; Hodges, K. V.; Van Soest, M. C.

    2017-12-01

    A laser ablation micro-analytical technique for (U-Th)/He dating has been shown to be an effective approach to the thermochronologic study of detrital zircons (Tripathy-Lang et al., J. Geophys. Res., 2013), while Evans et al. (J. Anal. At. Spectrom., 2015) and Horne et al. (Geochim. Cosmochim. Acta, 2016) demonstrated how the technique could be modified to enable laser ablation U/Pb and (U-Th)/He double-dating (LADD) of detrital zircon and titanite. These successes beg the question of whether or not LADD is viable for another commonly encountered detrital mineral: apatite. Exploratory LADD studies in Arizona State University's Group 18 Laboratories - using Durango fluorapatite, apatite from the Fish Canyon tuff, and detrital apatite from modern fluvial sediments in the eastern Sierra Nevada of California - illustrate that the method is indeed viable for detrital apatite. However, the method may not be appropriate for all detrital samples. For example, many apatite grains encountered in detrital samples from young orogenic settings have low concentrations of U and Th and small crystal sizes. This can lead to imprecise laser ablation (U-Th)/He dates, especially for very young grains potentially obscuring or inhibiting relevant interpretations of the data set.

  18. Current Nucleic Acid Extraction Methods and Their Implications to Point-of-Care Diagnostics

    PubMed Central

    Ali, Nasir; Rampazzo, Rita de Cássia Pontello; Krieger, Marco Aurelio

    2017-01-01

    Nucleic acid extraction (NAE) plays a vital role in molecular biology as the primary step for many downstream applications. Many modifications have been introduced to the original 1869 method. Modern processes are categorized into chemical or mechanical, each with peculiarities that influence their use, especially in point-of-care diagnostics (POC-Dx). POC-Dx is a new approach aiming to replace sophisticated analytical machinery with microanalytical systems, able to be used near the patient, at the point of care or point of need. Although notable efforts have been made, a simple and effective extraction method is still a major challenge for widespread use of POC-Dx. In this review, we dissected the working principle of each of the most common NAE methods, overviewing their advantages and disadvantages, as well their potential for integration in POC-Dx systems. At present, it seems difficult, if not impossible, to establish a procedure which can be universally applied to POC-Dx. We also discuss the effects of the NAE chemicals upon the main plastic polymers used to mass produce POC-Dx systems. We end our review discussing the limitations and challenges that should guide the quest for an efficient extraction method that can be integrated in a POC-Dx system. PMID:28785592

  19. Availability of Youth Services in U.S. Mental Health Treatment Facilities

    PubMed Central

    Cummings, Janet R.; Case, Brady G.; Ji, Xu; Marcus, Steven C.

    2015-01-01

    Despite concern about access to mental health (MH) services for youth, little is known about the specialty treatment infrastructure serving this population. We used national data to examine which types of MH treatment facilities (hospital- and community-based) were most likely to offer youth services and which types of communities were most likely to have this infrastructure. Larger (p<0.001) and privately owned (p<0.001) facilities were more likely to offer youth services. Rural counties, counties in which a majority of residents were nonwhite, and/or counties with a higher percentage of uninsured residents were less likely to have a community-based MH treatment facility that served youth (p<0.001). PMID:26467795

  20. Costs of facility-based HIV testing in Malawi, Zambia and Zimbabwe

    PubMed Central

    Mwenge, Lawrence; Sande, Linda; Mangenah, Collin; Ahmed, Nurilign; Kanema, Sarah; d’Elbée, Marc; Sibanda, Euphemia; Kalua, Thokozani; Ncube, Gertrude; Johnson, Cheryl C.; Hatzold, Karin; Cowan, Frances M.; Corbett, Elizabeth L.; Ayles, Helen; Maheswaran, Hendramoorthy

    2017-01-01

    Background Providing HIV testing at health facilities remains the most common approach to ensuring access to HIV treatment and prevention services for the millions of undiagnosed HIV-infected individuals in sub-Saharan Africa. We sought to explore the costs of providing these services across three southern African countries with high HIV burden. Methods Primary costing studies were undertaken in 54 health facilities providing HIV testing services (HTS) in Malawi, Zambia and Zimbabwe. Routinely collected monitoring and evaluation data for the health facilities were extracted to estimate the costs per individual tested and costs per HIV-positive individual identified. Costs are presented in 2016 US dollars. Sensitivity analysis explored key drivers of costs. Results Health facilities were testing on average 2290 individuals annually, albeit with wide variations. The mean cost per individual tested was US$5.03.9 in Malawi, US$4.24 in Zambia and US$8.79 in Zimbabwe. The mean cost per HIV-positive individual identified was US$79.58, US$73.63 and US$178.92 in Malawi, Zambia and Zimbabwe respectively. Both cost estimates were sensitive to scale of testing, facility staffing levels and the costs of HIV test kits. Conclusions Health facility based HIV testing remains an essential service to meet HIV universal access goals. The low costs and potential for economies of scale suggests an opportunity for further scale-up. However low uptake in many settings suggests that demand creation or alternative testing models may be needed to achieve economies of scale and reach populations less willing to attend facility based services. PMID:29036171

  1. Nanosized (mu12-Pt)Pd164-xPtx(CO)72(PPh3)20 (x approximately 7) containing Pt-centered four-shell 165-atom Pd-Pt core with unprecedented intershell bridging carbonyl ligands: comparative analysis of icosahedral shell-growth patterns with geometrically related Pd145(CO)x(PEt3)30 (x approximately 60) containing capped three-shell Pd145 core.

    PubMed

    Mednikov, Evgueni G; Jewell, Matthew C; Dahl, Lawrence F

    2007-09-19

    Presented herein are the preparation and crystallographic/microanalytical/magnetic/spectroscopic characterization of the Pt-centered four-shell 165-atom Pd-Pt cluster, (mu(12)-Pt)Pd(164-x)Pt(x)(CO)(72)(PPh(3))(20) (x approximately 7), 1, that replaces the geometrically related capped three-shell icosahedral Pd(145) cluster, Pd(145)(CO)(x)(PEt(3))(30) (x approximately 60), 2, as the largest crystallographically determined discrete transition metal cluster with direct metal-metal bonding. A detailed comparison of their shell-growth patterns gives rise to important stereochemical implications concerning completely unexpected structural dissimilarities as well as similarities and provides new insight concerning possible synthetic approaches for generation of multi-shell metal clusters. 1 was reproducibly prepared in small yields (<10%) from the reaction of Pd(10)(CO)(12)(PPh(3))(6) with Pt(CO)(2)(PPh(3))(2). Its 165-atom metal-core geometry and 20 PPh(3) and 72 CO ligands were established from a low-temperature (100 K) CCD X-ray diffraction study. The well-determined crystal structure is attributed largely to 1 possessing cubic T(h) (2/m3) site symmetry, which is the highest crystallographic subgroup of the noncrystallographic pseudo-icosahedral I(h) (2/m35) symmetry. The "full" four-shell Pd-Pt anatomy of 1 consists of: (a) shell 1 with the centered (mu(12)-Pt) atom encapsulated by the 12-atom icosahedral Pt(x)Pd(12-x) cage, x = 1.2(3); (b) shell 2 with the 42-atom nu(2) icosahedral Pt(x)Pd(42-x) cage, x = 3.5(5); (c) shell 3 with the anti-Mackay 60-atom semi-regular rhombicosidodecahedral Pt(x)Pd(60-x) cage, x = 2.2(6); (d) shell 4 with the 50-atom nu(2) pentagonal dodecahedral Pd(50) cage. The total number of crystallographically estimated Pt atoms, 8 +/- 3, which was obtained from least-squares (Pt(x)/Pd(1-x))-occupancy analysis of the X-ray data that conclusively revealed the central atom to be pure Pt (occupancy factor, x = 1.00(3)), is fortuitously in agreement with that of 7.6(7) found from an X-ray Pt/Pd microanalysis (WDS spectrometer) on three crystals of 1. Our utilization of this site-occupancy (Pt(x)Pd(1-x))-analysis for shells 1-3 originated from the microanalytical results; otherwise, the presumed metal-core composition would have been (mu(12)-Pt)Pd(164). [Alternatively, the (mu(12)-Pt)M(164) core-geometry of 1 may be viewed as a pseudo-Ih Pt-centered six-shell successive nu(1) polyhedral system, each with radially equivalent vertex atoms: Pt@M(12)(icosahedron)@M(30)(icosidodecahedron)@M(12)(icosahedron)@M(60)(rhombicosidodecahedron)@M(30)(icosidodecahedron)@M(20)(pentagonal dodecahedron)]. Completely surprising structural dissimilarities between 1 and 2 are: (1) to date 1 is only reproducibly isolated as a heterometallic Pd-Pt cluster with a central Pt instead of Pd atom; (2) the 50 atoms comprising the outer fourth nu(2) pentagonal dodecahedral shell in 1 are less than the 60 atoms of the inner third shell in 1, in contradistinction to shell-by-shell growth processes in all other known shell-based structures; (3) the 10 fewer PR3 ligands in 1 necessitate larger bulky PPh(3) ligands to protect the Pd-Pt core-geometry; (4) the 72 CO ligands consist of six bridging COs within each of the 12 pentagons in shell 4 that are coordinated to intershell metal atoms. SQUID magnetometry measurements showed a single-crystal sample of 1 to be diamagnetic over the entire temperature range of 10-300 K.

  2. Fixed Base Modal Testing Using the NASA GRC Mechanical Vibration Facility

    NASA Technical Reports Server (NTRS)

    Staab, Lucas D.; Winkel, James P.; Suarez, Vicente J.; Jones, Trevor M.; Napolitano, Kevin L.

    2016-01-01

    The Space Power Facility at NASA's Plum Brook Station houses the world's largest and most powerful space environment simulation facilities, including the Mechanical Vibration Facility (MVF), which offers the world's highest-capacity multi-axis spacecraft shaker system. The MVF was designed to perform sine vibration testing of a Crew Exploration Vehicle (CEV)-class spacecraft with a total mass of 75,000 pounds, center of gravity (cg) height above the table of 284 inches, diameter of 18 feet, and capability of 1.25 gravity units peak acceleration in the vertical and 1.0 gravity units peak acceleration in the lateral directions. The MVF is a six-degree-of-freedom, servo-hydraulic, sinusoidal base-shake vibration system that has the advantage of being able to perform single-axis sine vibration testing of large structures in the vertical and two lateral axes without the need to reconfigure the test article for each axis. This paper discusses efforts to extend the MVF's capabilities so that it can also be used to determine fixed base modes of its test article without the need for an expensive test-correlated facility simulation.

  3. Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing Facilities (SNFs) for FY 2016, SNF Value-Based Purchasing Program, SNF Quality Reporting Program, and Staffing Data Collection. Final Rule.

    PubMed

    2015-08-04

    This final rule updates the payment rates used under the prospective payment system (PPS) for skilled nursing facilities (SNFs) for fiscal year (FY) 2016. In addition, it specifies a SNF all-cause all-condition hospital readmission measure, as well as adopts that measure for a new SNF Value-Based Purchasing (VBP) Program, and includes a discussion of SNF VBP Program policies we are considering for future rulemaking to promote higher quality and more efficient health care for Medicare beneficiaries. Additionally, this final rule will implement a new quality reporting program for SNFs as specified in the Improving Medicare Post-Acute Care Transformation Act of 2014 (IMPACT Act). It also amends the requirements that a long-term care (LTC) facility must meet to qualify to participate as a skilled nursing facility (SNF) in the Medicare program, or a nursing facility (NF) in the Medicaid program, by establishing requirements that implement the provision in the Affordable Care Act regarding the submission of staffing information based on payroll data.

  4. The impact of targeted subsidies for facility-based delivery on access to care and equity - evidence from a population-based study in rural Burkina Faso.

    PubMed

    De Allegri, Manuela; Ridde, Valéry; Louis, Valérie R; Sarker, Malabika; Tiendrebéogo, Justin; Yé, Maurice; Müller, Olaf; Jahn, Albrecht

    2012-11-01

    We conducted the first population-based impact assessment of a financing policy introduced in Burkina Faso in 2007 on women's access to delivery services. The policy offers an 80 per cent subsidy for facility-based delivery. We collected information on delivery in five repeated cross-sectional surveys carried out from 2006 to 2010 on a representative sample of 1050 households in rural Nouna Health District. Over the 5 years, the proportion of facility-based deliveries increased from 49 to 84 per cent (P<0.001). The utilization gap across socio-economic quintiles, however, remained unchanged. The amount received for all services associated with births decreased by 67 per cent (P<0.001), but women continued to pay on average 1423 CFA (\\[euro]1=655 CFA), about 500 CFA more than the set tariff of 900 CFA. Our findings indicate the operational effectiveness of the policy in increasing the use of facility-based delivery services for women. The potential to reduce maternal mortality substantially has not yet been assessed by health outcome measures of neonatal and maternal mortality.

  5. Diarrhea Outbreak During U.S. Military Training In El Salvador

    DTIC Science & Technology

    2012-07-01

    Brigade (MEB) were detached to the Base Poligono in San Vicente, El Salvador as part of a military training and humanitarian assistance mission. The... Poligono included tent city (living quarters), latrines, hygiene facilities, the potable water distribution system, dining facility (DFAC), on-base vendor

  6. Surrogate Plant Data Base : Volume 3. Appendix D : Facilities Planning Data ; Operating Manpower, Manufacturing Budgets and Pre-Production Launch ...

    DOT National Transportation Integrated Search

    1983-05-01

    This four volume report consists of a data base describing "surrogate" automobile and truck manufacturing plants developed as part of a methodology for evaluating capital investment requirements in new manufacturing facilities to build new fleets of ...

  7. 6 CFR 27.220 - Tiering.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Tiering. 27.220 Section 27.220 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.220 Tiering. (a) Preliminary Determination of Risk-Based Tiering. Based on...

  8. 47 CFR 64.1310 - Payphone compensation procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... tendered for a quarter, the chief financial officer of the Completing Carrier shall submit to each payphone... Intermediate Carrier is a facilities-based long distance carrier that switches payphone calls to other facilities-based long distance carriers. (c) Unless the payphone service provider agrees to other reporting...

  9. NPDES Permit for F.E. Warren Air Force Base Missile Launch Facilities in Colorado

    EPA Pesticide Factsheets

    Under NPDES permit CO-0034789, the USAF, F. E. Warren Air Force Base, is authorized to discharge from the Missile Launch Facilities located in northeastern Colorado to unnamed drainage ditches located in the Cedar Creek and Pawnee Creek drainage basins.

  10. Toll Facilities in the United States : Bridges, Roads, Tunnels, Ferries

    DOT National Transportation Integrated Search

    1989-04-01

    Selected data on highway toll facilities in the United States are contained in Table T-1 of this report based on a survey of facilities in operation, financed, or under construction as of January 1, 1989. The data include information such as the name...

  11. Toll Facilities in the United States: Bridges - Roads - Tunnels - Ferries

    DOT National Transportation Integrated Search

    1987-04-01

    Selected data on highway toll facilities in the United States are contained in Table T-1 of this report based on a survey of facilities in operation, financed, or under construction as of January 1, 1987. The data includes information such as the nam...

  12. Facilities Management: A Program for the 1980s.

    ERIC Educational Resources Information Center

    Kaiser, Harvey H.

    1980-01-01

    Successful facilities management is described as based on a 10-point comprehensive program including: (1) physical planning policy; (2) facilities analysis; (3) management audit; (4) space utilization; (5) capital programs; (6) deferred maintenance; (7) controlled maintenance; (8) energy conservation; (9) environmental quality, health, and safety;…

  13. 78 FR 45983 - Acceptability of Corrective Action Programs for Fuel Cycle Facilities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... Programs for Fuel Cycle Facilities AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; withdrawal... withdrawing draft NUREG-2154, ``Acceptability of Corrective Action Programs for Fuel Cycle Facilities,'' based... determine whether a submittal for a Corrective Action Program (CAP), voluntarily submitted by fuel cycle...

  14. Creating Standards-Based Technology Education Facilities

    ERIC Educational Resources Information Center

    Daugherty, Michael K.; Klenke, Andrew M.; Neden, Michael

    2008-01-01

    One of the most intimidating tasks faced by new or practicing technology education teachers is the challenge of creating new facilities or renovating current facilities for a new purpose. While the fourth program standard in "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards (AETL)"…

  15. 40 CFR 256.41 - Recommendations for assessing the need for facilities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... facilities and practices and the need for new or expanded facilities and practices. (1) The needs assessment... require new capacity development, based on the needs assessment. ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommendations for assessing the need...

  16. 40 CFR 256.41 - Recommendations for assessing the need for facilities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... facilities and practices and the need for new or expanded facilities and practices. (1) The needs assessment... require new capacity development, based on the needs assessment. ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommendations for assessing the need...

  17. 40 CFR 256.41 - Recommendations for assessing the need for facilities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... facilities and practices and the need for new or expanded facilities and practices. (1) The needs assessment... require new capacity development, based on the needs assessment. ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommendations for assessing the need...

  18. Assessing healthcare quality using routine data: evaluating the performance of the national tuberculosis programme in South Africa.

    PubMed

    McLaren, Zoë M; Sharp, Alana R; Zhou, Jifang; Wasserman, Sean; Nanoo, Ananta

    2017-02-01

    To assess the performance of healthcare facilities by means of indicators based on guidelines for clinical care of TB, which is likely a good measure of overall facility quality. We assessed quality of care in all public health facilities in South Africa using graphical, correlation and locally weighted kernel regression analysis of routine TB test data. Facility performance falls short of national standards of care. Only 74% of patients with TB provided a second specimen for testing, 18% received follow-up testing and 14% received drug resistance testing. Only resistance testing rates improved over time, tripling between 2004 and 2011. National awareness campaigns and changes in clinical guidelines had only a transient impact on testing rates. The poorest performing facilities remained at the bottom of the rankings over the period of study. The optimal policy strategy requires both broad-based policies and targeted resources to poor performers. This approach to assessing facility quality of care can be adapted to other contexts and also provides a low-cost method for evaluating the effectiveness of proposed interventions. Devising targeted policies based on routine data is a cost-effective way to improve the quality of public health care provided. © 2016 John Wiley & Sons Ltd.

  19. Understanding the relationship between access to care and facility-based delivery through analysis of the 2008 Ghana Demographic Health Survey.

    PubMed

    Moyer, Cheryl A; McLaren, Zoë M; Adanu, Richard M; Lantz, Paula M

    2013-09-01

    To determine the types of access to care most strongly associated with facility-based delivery among women in Ghana. Data relating to the "5 As of Access" framework were extracted from the 2008 Ghana Demographic Health Survey and analyzed using multivariate logistic regression. In all, 55.5% of a weighted sample of 1102 women delivered in a healthcare facility, whereas 45.5% delivered at home. Affordability was the strongest access factor associated with delivery location, with health insurance coverage tripling the odds of facility delivery. Availability, accessibility (except urban residence), acceptability, and social access variables were not significant factors in the final models. Social access variables, including needing permission to seek healthcare and not being involved in decisions regarding healthcare, were associated with a reduced likelihood of facility-based delivery when examined individually. Multivariate analysis suggested that these variables reflected maternal literacy, health insurance coverage, and household wealth, all of which attenuated the effects of social access. Affordability was an important determinant of facility delivery in Ghana-even among women with health insurance-but social access variables had a mediating role. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  20. Implementation research to improve quality of maternal and newborn health care, Malawi.

    PubMed

    Brenner, Stephan; Wilhelm, Danielle; Lohmann, Julia; Kambala, Christabel; Chinkhumba, Jobiba; Muula, Adamson S; De Allegri, Manuela

    2017-07-01

    To evaluate the impact of a performance-based financing scheme on maternal and neonatal health service quality in Malawi. We conducted a non-randomized controlled before and after study to evaluate the effects of district- and facility-level performance incentives for health workers and management teams. We assessed changes in the facilities' essential drug stocks, equipment maintenance and clinical obstetric care processes. Difference-in-difference regression models were used to analyse effects of the scheme on adherence to obstetric care treatment protocols and provision of essential drugs, supplies and equipment. We observed 33 health facilities, 23 intervention facilities and 10 control facilities and 401 pregnant women across four districts. The scheme improved the availability of both functional equipment and essential drug stocks in the intervention facilities. We observed positive effects in respect to drug procurement and clinical care activities at non-intervention facilities, likely in response to improved district management performance. Birth assistants' adherence to clinical protocols improved across all studied facilities as district health managers supervised and coached clinical staff more actively. Despite nation-wide stock-outs and extreme health worker shortages, facilities in the study districts managed to improve maternal and neonatal health service quality by overcoming bottlenecks related to supply procurement, equipment maintenance and clinical performance. To strengthen and reform health management structures, performance-based financing may be a promising approach to sustainable improvements in quality of health care.

  1. Analysis of Student Satisfaction Toward Quality of Service Facility

    NASA Astrophysics Data System (ADS)

    Napitupulu, D.; Rahim, R.; Abdullah, D.; Setiawan, MI; Abdillah, LA; Ahmar, AS; Simarmata, J.; Hidayat, R.; Nurdiyanto, H.; Pranolo, A.

    2018-01-01

    The development of higher education is very rapid rise to the tight competition both public universities and private colleges. XYZ University realized to win the competition, required continuous quality improvement, including the quality of existing service facilities. Amenities quality services is believed to support the success of the learning activities and improve user satisfaction. This study aims to determine the extent to which the quality of the services effect on user satisfaction. The research method used is survey-based questionnaire that measure perception and expectation. The results showed a gap between perception and expectations of the respondents have a negative value for each item. This means XYZ service facility at the university is not currently meet the expectations of society members. Three service facility that has the lowest index is based on the perception of respondents is a laboratory (2.56), computer and multimedia (2.63) as well as wifi network (2.99). The magnitude of the correlation between satisfaction with the quality of service facilities is 0.725 which means a strong and positive relationship. The influence of the quality of service facilities to the satisfaction of the students is 0.525 meaning that the variable quality of the services facility can explain 52.5% of the variable satisfaction. The study provided recommendations for improvements to enhance the quality of services facility at the XYZ university facilities.

  2. Determinants of Contraceptive Availability at Medical Facilities in the Department of Veterans Affairs

    PubMed Central

    Cope, Jacqueline R; Yano, Elizabeth M; Lee, Martin L; Washington, Donna L

    2006-01-01

    OBJECTIVE To describe the variation in provision of hormonal and intrauterine contraception among Veterans Affairs (VA) facilities. DESIGN Key informant, cross-sectional survey of 166 VA medical facilities. Data from public use data sets and VA administrative databases were linked to facility data to further characterize their contextual environments. PARTICIPANTS All VA hospital-based and affiliated community-based outpatient clinics delivering services to at least 400 unique women during fiscal year 2000. MEASUREMENTS Onsite availability of hormonal contraceptive prescription and intrauterine device (IUD) placement. RESULTS Ninety-seven percent of facilities offered onsite prescription and management of hormonal contraception whereas 63% offered placement of IUDs. After adjusting for facility caseload of reproductive-aged women, 3 organizational factors were independently associated with onsite IUD placement: (1) onsite gynecologist (adjusted odds ratio [OR], 20.35; 95% confidence interval [CI], 7.02 to 58.74; P<.001); (2) hospital-based in contrast to community-based practice (adjusted OR, 5.49; 95% CI, 1.16 to 26.10; P=.03); and (3) availability of a clinician providing women's health training to other clinicians (adjusted OR, 3.40; 95% CI 1.19 to 9.76; P=.02). CONCLUSIONS VA's provision of hormonal and intrauterine contraception is in accordance with community standards, although onsite availability is not universal. Although contraception is a crucial component of a woman's health maintenance, her ability to obtain certain contraceptives from the facility where she obtains her primary care is largely influenced by the availability of a gynecologist. Further research is needed to determine how fragmentation of women's care into reproductive and nonreproductive services impacts access to contraception and the incidence of unintended pregnancy. PMID:16637943

  3. Treatment of men with high-risk prostate cancer based on race, insurance coverage, and access to advanced technology.

    PubMed

    Gerhard, Robert Steven; Patil, Dattatraya; Liu, Yuan; Ogan, Kenneth; Alemozaffar, Mehrdad; Jani, Ashesh B; Kucuk, Omer N; Master, Viraj A; Gillespie, Theresa W; Filson, Christopher P

    2017-05-01

    We characterized factors related to nondefinitive management (NDM) of patients with high-risk prostate cancer and assessed impact from race, insurance status, and facility-level volume of technologically advanced prostate cancer treatments (i.e., intensity-modulated radiation therapy, robotic-assisted laparoscopic radical prostatectomy) on this outcome. We identified men with high-risk localized prostate cancer (based on D׳Amico criteria) in the National Cancer Database (2010-2012). Primary outcome was NDM (i.e., delayed/no treatment with prostatectomy/radiation therapy or androgen-deprivation monotherapy). Treating facilities were classified by quartiles of proportions of patients treated with advanced technology. Multivariable regression estimated odds of primary outcome based on race, insurance status, and facility-level technology use, and evaluated for interactions between these covariates. Among 60,300 patients, 9,265 (15.4%) received NDM. This was more common among non-White men (P<0.001), Medicaid/uninsured patients (P<0.001), and those managed at facilities in the lowest quartile of technology use (25.1% vs. 11.0% highest, P<0.001). Though NDM was common among non-White men with Medicaid/no insurance treated at low-technology centers (43% vs. 10% White, private/Medicare, high-tech facility; adjusted odds ratios = 7.18, P<0.001), this was less likely if this group was managed at a high-tech hospital (22% vs. 43% low-tech, P<0.001). Technology use at a facility correlates with high-quality prostate cancer care and is associated with diminished disparities based on insurance status and patient race. More research is required to characterize other facility-level factors explaining these findings. Published by Elsevier Inc.

  4. Towards ion beam therapy based on laser plasma accelerators.

    PubMed

    Karsch, Leonhard; Beyreuther, Elke; Enghardt, Wolfgang; Gotz, Malte; Masood, Umar; Schramm, Ulrich; Zeil, Karl; Pawelke, Jörg

    2017-11-01

    Only few ten radiotherapy facilities worldwide provide ion beams, in spite of their physical advantage of better achievable tumor conformity of the dose compared to conventional photon beams. Since, mainly the large size and high costs hinder their wider spread, great efforts are ongoing to develop more compact ion therapy facilities. One promising approach for smaller facilities is the acceleration of ions on micrometre scale by high intensity lasers. Laser accelerators deliver pulsed beams with a low pulse repetition rate, but a high number of ions per pulse, broad energy spectra and high divergences. A clinical use of a laser based ion beam facility requires not only a laser accelerator providing beams of therapeutic quality, but also new approaches for beam transport, dosimetric control and tumor conformal dose delivery procedure together with the knowledge of the radiobiological effectiveness of laser-driven beams. Over the last decade research was mainly focused on protons and progress was achieved in all important challenges. Although currently the maximum proton energy is not yet high enough for patient irradiation, suggestions and solutions have been reported for compact beam transport and dose delivery procedures, respectively, as well as for precise dosimetric control. Radiobiological in vitro and in vivo studies show no indications of an altered biological effectiveness of laser-driven beams. Laser based facilities will hardly improve the availability of ion beams for patient treatment in the next decade. Nevertheless, there are possibilities for a need of laser based therapy facilities in future.

  5. STD testing policies and practices in U.S. city and county jails.

    PubMed

    Parece, M S; Herrera, G A; Voigt, R F; Middlekauff, S L; Irwin, K L

    1999-09-01

    Studies have shown that sexually transmitted disease (STD) rates are high in the incarcerated population. However, little is known about STD testing policies or practices in jails. To assess STD testing policies and practices in jails. The Division of STD Prevention developed and distributed an e-mail survey to 94 counties reporting more than 40 primary and secondary cases in 1996 or having cities with more than 200,000 persons. State and local STD program managers completed the assessment in collaboration with health departments and the main jail facilities in the selected counties. Most facilities (52-77%) had a policy for STD screening based only on symptoms or by arrestee request, and in these facilities, 0.2% to 6% of arrestees were tested. Facilities having a policy of offering routine testing tested only 3% to 45% of arrestees. Large facilities, facilities using public providers, and facilities routinely testing for syphilis using Stat RPR tested significantly more arrestees (P<0.05). Approximately half of the arrestees were released within 48 hours after intake, whereas 45% of facilities did not have STD testing results until after 48 hours. Most facilities had a policy for STD screening based only on symptoms or by arrestee request. Facilities having a policy of routine STD testing are not testing most of the arrestees. There is a small window (<48 hours) for STD testing and treatment before release. Smaller jails and facilities using private providers may need additional resources to increase STD testing levels. Correctional facilities should be considered an important setting for STD public health intervention where routine rapid STD screening and treatment on-site could be implemented.

  6. Quantitative Properties of the Macro Supply and Demand Structure for Care Facilities for Elderly in Japan.

    PubMed

    Nishino, Tatsuya

    2017-12-01

    As the Asian country with the most aged population, Japan, has been modifying its social welfare system. In 2000, the Japanese social care vision turned towards meeting the elderly's care needs in their own homes with proper formal care services. This study aims to understand the quantitative properties of the macro supply and demand structure for facilities for the elderly who require support or long-term care throughout Japan and present them as index values. Additionally, this study compares the targets for establishing long-term care facilities set by Japan's Ministry of Health, Labor and Welfare for 2025. In 2014, approximately 90% of all the people who were certified as requiring support and long-term care and those receiving preventive long-term care or long-term care services, were 75 years or older. The target increases in the number of established facilities by 2025 (for the 75-years-or-older population) were calculated to be 3.3% for nursing homes; 2.71% for long-term-care health facilities; 1.7% for group living facilities; and, 1.84% for community-based multi-care facilities. It was revealed that the establishment targets for 2025 also increase over current projections with the expected increase of the absolute number of users of group living facilities and community-based multi-care facilities. On the other hand, the establishment target for nursing homes remains almost the same as the current projection, whereas that for long-term-care health facilities decreases. These changes of facility ratios reveal that the Japanese social care system is shifting to realize 'Ageing in Place'. When considering households' tendencies, the target ratios for established facilities are expected to be applied to the other countries in Asia.

  7. Quantitative Properties of the Macro Supply and Demand Structure for Care Facilities for Elderly in Japan

    PubMed Central

    Nishino, Tatsuya

    2017-01-01

    As the Asian country with the most aged population, Japan, has been modifying its social welfare system. In 2000, the Japanese social care vision turned towards meeting the elderly’s care needs in their own homes with proper formal care services. This study aims to understand the quantitative properties of the macro supply and demand structure for facilities for the elderly who require support or long-term care throughout Japan and present them as index values. Additionally, this study compares the targets for establishing long-term care facilities set by Japan’s Ministry of Health, Labor and Welfare for 2025. In 2014, approximately 90% of all the people who were certified as requiring support and long-term care and those receiving preventive long-term care or long-term care services, were 75 years or older. The target increases in the number of established facilities by 2025 (for the 75-years-or-older population) were calculated to be 3.3% for nursing homes; 2.71% for long-term-care health facilities; 1.7% for group living facilities; and, 1.84% for community-based multi-care facilities. It was revealed that the establishment targets for 2025 also increase over current projections with the expected increase of the absolute number of users of group living facilities and community-based multi-care facilities. On the other hand, the establishment target for nursing homes remains almost the same as the current projection, whereas that for long-term-care health facilities decreases. These changes of facility ratios reveal that the Japanese social care system is shifting to realize ‘Ageing in Place’. When considering households’ tendencies, the target ratios for established facilities are expected to be applied to the other countries in Asia. PMID:29194405

  8. Prevalence of pregnancy-related complications and course of labour of surviving women who gave birth in selected health facilities in Rwanda: a health facility-based, cross-sectional study.

    PubMed

    Semasaka Sengoma, Jean Paul; Krantz, Gunilla; Nzayirambaho, Manasse; Munyanshongore, Cyprien; Edvardsson, Kristina; Mogren, Ingrid

    2017-07-09

    This study estimated health facility-based prevalence for pre-eclampsia/eclampsia, postpartum haemorrhage and caesarean section (CS) due to prolonged labour/dystocia. The background characteristics of Rwandan pregnant women, the course of labour and the level of healthcare were investigated in relation to pregnancy and delivery outcomes. This is health facility-based study and data were collected in 2014-2015 through structured interviews and medical records (n=817) in Kigali and Northern Province, Rwanda. Frequencies and prevalence were used to describe participants' background factors, labour and delivery-related characteristics. Bivariable and multivariable logistic regression models were performed for different background factors and pregnancy/delivery outcomes. Pre-eclampsia/eclampsia, postpartum haemorrhage and CS due to prolonged labour/dystocia represented 1%, 2.7% and 5.4% of all participants, respectively. In total, 56.4% of the participants were transferred from facilities with low levels to those with higher levels of healthcare, and the majority were transferred from health centres to district hospitals, with CS as the main reason for transfer. Participants who arrived at the health facility with cervical dilation grade of ≤3 cm spent more hours in maternity ward than those who arrived with cervical dilatation grade of ≥4 cm. Risk factors for CS due to prolonged labour or dystocia were poor households, nulliparity and residence far from health facility. The estimated health facility-based prevalence of pregnancy-related complications was relatively low in this sample from Rwanda. CS was the main reason for the transfer of pregnant women from health centres to district hospitals. Upgrading the capacity of health centres in the management of pregnant women in Rwanda may improve maternal and fetal health. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Enhancing resiliency for elderly populations : Shelter-in-place planning and training at facilities serving elderly populations through the Rhode Island Senior Resiliency Project.

    PubMed

    Smith, Richard; Mozzer, Michael; Albanese, Joseph; Paturas, James; Gold, Julia

    2017-06-01

    Elderly populations are disproportionately affected by disasters. In part, this is true because for many older adults, special assistance is needed to mitigate the consequences of disasters on their health and wellbeing. In addition, many older adults may reside in diverse living complexes such as long-term care facilities, assisted living facilities and independent-living senior housing complexes. Planning for each type of facility is different and the unique features of these facilities must be considered to develop readiness to deal with disasters. Based on this, the Rhode Island Department of Health established the Senior Resiliency Project to bolster the level of resiliency for the types of living facilities housing older adults. The project involves performing onsite assessments of energy resources, developing site-specific sheltering-inplace and energy resiliency plans, and educating and training facility employees and residents on these plans and steps they can take to be better prepared. Based on the feasibility of conducting these activities within a variety of facilities housing older adults, the project is segmented into three phases. This paper describes survey findings, outcomes of interventions, challenges and recommendations for bridging gaps observed in phases 1 and 2 of the project.

  10. Accelerator Physics Working Group Summary

    NASA Astrophysics Data System (ADS)

    Li, D.; Uesugi, T.; Wildnerc, E.

    2010-03-01

    The Accelerator Physics Working Group addressed the worldwide R&D activities performed in support of future neutrino facilities. These studies cover R&D activities for Super Beam, Beta Beam and muon-based Neutrino Factory facilities. Beta Beam activities reported the important progress made, together with the research activity planned for the coming years. Discussion sessions were also organized jointly with other working groups in order to define common ground for the optimization of a future neutrino facility. Lessons learned from already operating neutrino facilities provide key information for the design of any future neutrino facility, and were also discussed in this meeting. Radiation damage, remote handling for equipment maintenance and exchange, and primary proton beam stability and monitoring were among the important subjects presented and discussed. Status reports for each of the facility subsystems were presented: proton drivers, targets, capture systems, and muon cooling and acceleration systems. The preferred scenario for each type of possible future facility was presented, together with the challenges and remaining issues. The baseline specification for the muon-based Neutrino Factory was reviewed and updated where required. This report will emphasize new results and ideas and discuss possible changes in the baseline scenarios of the facilities. A list of possible future steps is proposed that should be followed up at NuFact10.

  11. A cross sectional comparison of postnatal care quality in facilities participating in a maternal health voucher program versus non-voucher facilities in Kenya.

    PubMed

    Warren, Charlotte E; Abuya, Timothy; Kanya, Lucy; Obare, Francis; Njuki, Rebecca; Temmerman, Marleen; Bellows, Ben

    2015-07-24

    Health service fees constitute substantial barriers for women seeking childbirth and postnatal care. In an effort to reduce health inequities, the government of Kenya in 2006 introduced the output-based approach (OBA), or voucher programme, to increase poor women's access to quality Safe Motherhood services including postnatal care. To help improve service quality, OBA programmes purchase services on behalf of the poor and marginalised, with provider reimbursements for verified services. Kenya's programme accredited health facilities in three districts as well as in two informal Nairobi settlements. Postnatal care quality in voucher health facilities (n = 21) accredited in 2006 and in similar non-voucher health facilities (n = 20) are compared with cross sectional data collected in 2010. Summary scores for quality were calculated as additive sums of specific aspects of each attribute (structure, process, outcome). Measures of effect were assessed in a linear regression model accounting for clustering at facility level. Data were analysed using Stata 11.0. The overall quality of postnatal care is poor in voucher and non-voucher facilities, but many facilities demonstrated 'readiness' for postnatal care (structural attributes: infrastructure, equipment, supplies, staffing, training) indicated by high scores (83/111), with public voucher facilities scoring higher than public non-voucher facilities. The two groups of facilities evinced no significant differences in postnatal care mean process scores: 14.2/55 in voucher facilities versus 16.4/55 in non-voucher facilities; coefficient: -1.70 (-4.9, 1.5), p = 0.294. Significantly more newborns were seen within 48 hours (83.5% versus 72.1%: p = 0.001) and received Bacillus Calmette-Guerin (BCG) (82.5% versus 76.5%: p < 0.001) at voucher facilities than at non-voucher facilities. Four years after facility accreditation in Kenya, scores for postnatal care quality are low in all facilities, even those with Safe Motherhood vouchers. We recommend the Kenya OBA programme review its Safe Motherhood reimbursement package and draw lessons from supply side results-based financing initiatives, to improve postnatal care quality.

  12. Lessons Learned from Radioactive Waste Storage and Disposal Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Esh, David W.; Bradford, Anna H.

    2008-01-15

    The safety of radioactive waste disposal facilities and the decommissioning of complex sites may be predicated on the performance of engineered and natural barriers. For assessing the safety of a waste disposal facility or a decommissioned site, a performance assessment or similar analysis is often completed. The analysis is typically based on a site conceptual model that is developed from site characterization information, observations, and, in many cases, expert judgment. Because waste disposal facilities are sited, constructed, monitored, and maintained, a fair amount of data has been generated at a variety of sites in a variety of natural systems. Thismore » paper provides select examples of lessons learned from the observations developed from the monitoring of various radioactive waste facilities (storage and disposal), and discusses the implications for modeling of future waste disposal facilities that are yet to be constructed or for the development of dose assessments for the release of decommissioning sites. Monitoring has been and continues to be performed at a variety of different facilities for the disposal of radioactive waste. These include facilities for the disposal of commercial low-level waste (LLW), reprocessing wastes, and uranium mill tailings. Many of the lessons learned and problems encountered provide a unique opportunity to improve future designs of waste disposal facilities, to improve dose modeling for decommissioning sites, and to be proactive in identifying future problems. Typically, an initial conceptual model was developed and the siting and design of the disposal facility was based on the conceptual model. After facility construction and operation, monitoring data was collected and evaluated. In many cases the monitoring data did not comport with the original site conceptual model, leading to additional investigation and changes to the site conceptual model and modifications to the design of the facility. The following cases are discussed: commercial LLW disposal facilities; uranium mill tailings disposal facilities; and reprocessing waste storage and disposal facilities. The observations developed from the monitoring and maintenance of waste disposal and storage facilities provide valuable lessons learned for the design and modeling of future waste disposal facilities and the decommissioning of complex sites.« less

  13. 12 CFR 7.5006 - Data processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... services, facilities (including equipment, technology, and personnel), data bases, advice and access to such services, facilities, data bases and advice, for itself and for others, where the data is banking... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Data processing. 7.5006 Section 7.5006 Banks...

  14. 12 CFR 7.5006 - Data processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... services, facilities (including equipment, technology, and personnel), data bases, advice and access to such services, facilities, data bases and advice, for itself and for others, where the data is banking... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Data processing. 7.5006 Section 7.5006 Banks...

  15. 12 CFR 7.5006 - Data processing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... services, facilities (including equipment, technology, and personnel), data bases, advice and access to such services, facilities, data bases and advice, for itself and for others, where the data is banking... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Data processing. 7.5006 Section 7.5006 Banks...

  16. Experience with a UNIX based batch computing facility for H1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gerhards, R.; Kruener-Marquis, U.; Szkutnik, Z.

    1994-12-31

    A UNIX based batch computing facility for the H1 experiment at DESY is described. The ultimate goal is to replace the DESY IBM mainframe by a multiprocessor SGI Challenge series computer, using the UNIX operating system, for most of the computing tasks in H1.

  17. 7 CFR 1942.18 - Community facilities-Planning, bidding, contracting, constructing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... exceptions must have prior National Office concurrence. (5) Energy conservation. Facility design should consider cost effective energy saving measures or devices. (6) Lead base paints. Lead base paints shall not... meet the requirements of the Safe Drinking Water Act (Pub. L. 93-523) and provide water of a quality...

  18. 7 CFR 1942.18 - Community facilities-Planning, bidding, contracting, constructing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... exceptions must have prior National Office concurrence. (5) Energy conservation. Facility design should consider cost effective energy saving measures or devices. (6) Lead base paints. Lead base paints shall not... meet the requirements of the Safe Drinking Water Act (Pub. L. 93-523) and provide water of a quality...

  19. 7 CFR 1942.18 - Community facilities-Planning, bidding, contracting, constructing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... exceptions must have prior National Office concurrence. (5) Energy conservation. Facility design should consider cost effective energy saving measures or devices. (6) Lead base paints. Lead base paints shall not... meet the requirements of the Safe Drinking Water Act (Pub. L. 93-523) and provide water of a quality...

  20. Responsible Adult Culture (RAC): Cognitive and Behavioral Changes at a Community-Based Correctional Facility

    ERIC Educational Resources Information Center

    Devlin, Renee S.; Gibbs, John C.

    2010-01-01

    This article examined cognitive and behavioral changes among participants in Responsible Adult Culture (RAC), a cognitive-behavioral (especially, cognitive restructuring) treatment program in use at the Franklin County Community-Based Correctional Facility (CBCF). Participants were adult felony offenders (approximately three-fourths male). A…

  1. Integrity-Based Budgeting

    ERIC Educational Resources Information Center

    Kaleba, Frank

    2008-01-01

    The central problem for the facility manager of large portfolios is not the accuracy of data, but rather data integrity. Data integrity means that it's (1) acceptable to the users; (2) based upon an objective source; (3) reproducible; and (4) internally consistent. Manns and Katsinas, in their January/February 2006 Facilities Manager article…

  2. 38 CFR 17.80 - Alcohol and drug dependence or abuse treatment and rehabilitation in residential and...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... other community-based treatment facilities, when considered to be medically advantageous and cost... dependence or abuse treatment and rehabilitation in residential and nonresidential facilities by contract. 17... rehabilitation in residential and nonresidential facilities by contract. (a) Alcohol and drug dependence or abuse...

  3. The Otis Weather Test Facility at Otis ANGB, Falmouth, MA : an aviation weather resource

    DOT National Transportation Integrated Search

    2004-10-06

    The Otis Weather Test Facility (WTF) is located on the US Air National Guard Base, Cape Cod, MA. The Facility was originally established by the US Air Force Cambridge Research Laboratory [now Air Force Research Laboratory (AFRL)] in 1974 to develop a...

  4. 48 CFR 252.239-7011 - Special construction and equipment charges.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the Contractor stops using facilities or equipment which the Government has, in whole or part... equipment attributable to the Government's contribution. Determine the value of the facilities and equipment...— (1) Recurring charges for the services, facilities, and equipment do not include in the rate base any...

  5. ELEVATION OF FACILITY 667 WITH GRADUATED SCALE IN 1' INCREMENTS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ELEVATION OF FACILITY 667 WITH GRADUATED SCALE IN 1' INCREMENTS. NOTE: THE TORPEDO IN THE FOREGROUND IS A DISPLAY ASSOCIATED WITH FACILITY 683. VIEW FACING NORTHEAST - U.S. Naval Base, Pearl Harbor, Gymnasium Building, North Waterfront & Pierce Street near Berth S-13, Pearl City, Honolulu County, HI

  6. Data-Linking Requirements in Facilities Condition Audit RFPs.

    ERIC Educational Resources Information Center

    DeFranco, Randall W.

    2002-01-01

    Discusses why, when preparing a Request for Proposal (RFP) for Facilities Condition Audit (FCA)--including software-based delivery of findings--facilities managers should avoid complicating the bidding process with nondescript data-linking requirements. Presents ways to get an apples-to-apples comparison of bids for a proposed FCA project and…

  7. NIST Document Sharing Test Facility

    Science.gov Websites

    NIST Document Sharing Test Facility This site supports the IHE effort in Document Sharing as part . This test facility is based on the IHE IT Infrastructure Technical Framework. All testing done against that Patient IDs be pre-registered before submitting metadata about them. To allocate new patient IDs

  8. 78 FR 73144 - Acceleration of Broadband Deployment by Improving Wireless Facilities Siting Policies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ..., ground-based enclosures, battery back-up power systems, grounding equipment, power transfer switch, and... No. 11-59; FCC 13-122] Acceleration of Broadband Deployment by Improving Wireless Facilities Siting... of new wireless facilities and on rules to implement statutory provisions governing State and local...

  9. 29 CFR 1910.141 - Sanitation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...), toilet facilities, in toilet rooms separate for each sex, shall be provided in all places of employment in accordance with table J-1 of this section. The number of facilities to be provided for each sex shall be based on the number of employees of that sex for whom the facilities are furnished. Where...

  10. Campania Region's Educational Quality Facilities Project

    ERIC Educational Resources Information Center

    Ponti, Giorgio

    2009-01-01

    This article describes the Educational Quality Facilities project undertaken by Italy's Campania Region to provide quality facilities to all of its communities basing new spaces on the "Flexible Learning Module". The objectives of the five-year project are to: build and equip new educational spaces; improve the quality of existing…

  11. Anatomy Education in Namibia: Balancing Facility Design and Curriculum Development

    ERIC Educational Resources Information Center

    Wessels, Quenton; Vorster, Willie; Jacobson, Christian

    2012-01-01

    The anatomy curriculum at Namibia's first, and currently only, medical school is clinically oriented, outcome-based, and includes all of the components of modern anatomical sciences i.e., histology, embryology, neuroanatomy, gross, and clinical anatomy. The design of the facilities and the equipment incorporated into these facilities were directed…

  12. Academic Computing Facilities and Services in Higher Education--A Survey.

    ERIC Educational Resources Information Center

    Warlick, Charles H.

    1986-01-01

    Presents statistics about academic computing facilities based on data collected over the past six years from 1,753 institutions in the United States, Canada, Mexico, and Puerto Rico for the "Directory of Computing Facilities in Higher Education." Organizational, functional, and financial characteristics are examined as well as types of…

  13. National Biomedical Tracer Facility. Project definition study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schafer, R.

    We request a $25 million government-guaranteed, interest-free loan to be repaid over a 30-year period for construction and initial operations of a cyclotron-based National Biomedical Tracer Facility (NBTF) in North Central Texas. The NBTF will be co-located with a linear accelerator-based commercial radioisotope production facility, funded by the private sector at approximately $28 million. In addition, research radioisotope production by the NBTF will be coordinated through an association with an existing U.S. nuclear reactor center that will produce research and commercial radioisotopes through neutron reactions. The combined facilities will provide the full range of technology for radioisotope production and research:more » fast neutrons, thermal neutrons, and particle beams (H{sup -}, H{sup +}, and D{sup +}). The proposed NBTF facility includes an 80 MeV, 1 mA H{sup -} cyclotron that will produce proton-induced (neutron deficient) research isotopes.« less

  14. Clean room survey and assessment, volume 5, appendix H

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The scope of this task is to perform a comparative analysis of the various Environmental Control Life Support System (ECLSS) options for different growth scenarios. The Space Station Freedom ECLSS design and existing ground-based clean room facilities are used as a baseline for comparison. Specifically addressed here are the ground based clean room facilities at the Marshall Space Flight Center (MSFC). Given here is an evaluation of the facilities, equipment, technologies, and procedures used to maintain specified environments in typical aerospace industrial areas. Twenty-five specific clean rooms are evaluated. The objectives were to collect, compare, and catalog data for each specified facility in the areas of engineering and design, construction materials, work stations, contamination control, particulate elimination, entry systems, and instrumentation, and to make recommendations concerning enhancements required to assure an efficient and orderly evolution of MSFC clean room environmental control facilities.

  15. Preventing Heel Pressure Ulcers: Sustained Quality Improvement Initiative in a Canadian Acute Care Facility.

    PubMed

    Hanna-Bull, Debbie

    2016-01-01

    The setting for this quality improvement initiative designed to reduce the prevalence of facility-acquired heel pressure ulcers was a regional, acute-care, 490-bed facility in Ontario, Canada, responsible for dialysis, vascular, and orthopedic surgery. An interdisciplinary skin and wound care team designed an evidence-based quality improvement initiative based on a systematic literature review and standardization of heel offloading methods. The prevalence of heel pressure ulcers was measured at baseline (immediately prior to implementation of initiative) and at 1 and 4 years following implementation. The prevalence of facility-acquired heel pressure ulcers was 5.8% when measured before project implementation. It was 4.2% at 1 year following implementation and 1.6% when measured at the end of the 4-year initiative. Outcomes demonstrate that the initiative resulted in a continuous and sustained reduction in facility-acquired heel pressure ulcer incidence over a 4-year period.

  16. Comparing facility-level methane emission rate estimates at natural gas gathering and boosting stations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaughn, Timothy L.; Bell, Clay S.; Yacovitch, Tara I.

    Coordinated dual-tracer, aircraft-based, and direct component-level measurements were made at midstream natural gas gathering and boosting stations in the Fayetteville shale (Arkansas, USA). On-site component-level measurements were combined with engineering estimates to generate comprehensive facility-level methane emission rate estimates ('study on-site estimates (SOE)') comparable to tracer and aircraft measurements. Combustion slip (unburned fuel entrained in compressor engine exhaust), which was calculated based on 111 recent measurements of representative compressor engines, accounts for an estimated 75% of cumulative SOEs at gathering stations included in comparisons. Measured methane emissions from regenerator vents on glycol dehydrator units were substantially larger than predicted bymore » modelling software; the contribution of dehydrator regenerator vents to the cumulative SOE would increase from 1% to 10% if based on direct measurements. Concurrent measurements at 14 normally-operating facilities show relative agreement between tracer and SOE, but indicate that tracer measurements estimate lower emissions (regression of tracer to SOE = 0.91 (95% CI = 0.83-0.99), R2 = 0.89). Tracer and SOE 95% confidence intervals overlap at 11/14 facilities. Contemporaneous measurements at six facilities suggest that aircraft measurements estimate higher emissions than SOE. Aircraft and study on-site estimate 95% confidence intervals overlap at 3/6 facilities. The average facility level emission rate (FLER) estimated by tracer measurements in this study is 17-73% higher than a prior national study by Marchese et al.« less

  17. Comparing facility-level methane emission rate estimates at natural gas gathering and boosting stations

    DOE PAGES

    Vaughn, Timothy L.; Bell, Clay S.; Yacovitch, Tara I.; ...

    2017-02-09

    Coordinated dual-tracer, aircraft-based, and direct component-level measurements were made at midstream natural gas gathering and boosting stations in the Fayetteville shale (Arkansas, USA). On-site component-level measurements were combined with engineering estimates to generate comprehensive facility-level methane emission rate estimates ('study on-site estimates (SOE)') comparable to tracer and aircraft measurements. Combustion slip (unburned fuel entrained in compressor engine exhaust), which was calculated based on 111 recent measurements of representative compressor engines, accounts for an estimated 75% of cumulative SOEs at gathering stations included in comparisons. Measured methane emissions from regenerator vents on glycol dehydrator units were substantially larger than predicted bymore » modelling software; the contribution of dehydrator regenerator vents to the cumulative SOE would increase from 1% to 10% if based on direct measurements. Concurrent measurements at 14 normally-operating facilities show relative agreement between tracer and SOE, but indicate that tracer measurements estimate lower emissions (regression of tracer to SOE = 0.91 (95% CI = 0.83-0.99), R2 = 0.89). Tracer and SOE 95% confidence intervals overlap at 11/14 facilities. Contemporaneous measurements at six facilities suggest that aircraft measurements estimate higher emissions than SOE. Aircraft and study on-site estimate 95% confidence intervals overlap at 3/6 facilities. The average facility level emission rate (FLER) estimated by tracer measurements in this study is 17-73% higher than a prior national study by Marchese et al.« less

  18. Rehabilitation of the Rocket Vehicle Integration Test Stand at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    Jones, Daniel S.; Ray, Ronald J.; Phillips, Paul

    2005-01-01

    Since initial use in 1958 for the X-15 rocket-powered research airplane, the Rocket Engine Test Facility has proven essential for testing and servicing rocket-powered vehicles at Edwards Air Force Base. For almost two decades, several successful flight-test programs utilized the capability of this facility. The Department of Defense has recently demonstrated a renewed interest in propulsion technology development with the establishment of the National Aerospace Initiative. More recently, the National Aeronautics and Space Administration is undergoing a transformation to realign the organization, focusing on the Vision for Space Exploration. These initiatives provide a clear indication that a very capable ground-test stand at Edwards Air Force Base will be beneficial to support the testing of future access-to-space vehicles. To meet the demand of full integration testing of rocket-powered vehicles, the NASA Dryden Flight Research Center, the Air Force Flight Test Center, and the Air Force Research Laboratory have combined their resources in an effort to restore and upgrade the original X-15 Rocket Engine Test Facility to become the new Rocket Vehicle Integration Test Stand. This report describes the history of the X-15 Rocket Engine Test Facility, discusses the current status of the facility, and summarizes recent efforts to rehabilitate the facility to support potential access-to-space flight-test programs. A summary of the capabilities of the facility is presented and other important issues are discussed.

  19. The impact of community health worker-led home delivery of antiretroviral therapy on virological suppression: a non-inferiority cluster-randomized health systems trial in Dar es Salaam, Tanzania.

    PubMed

    Geldsetzer, Pascal; Francis, Joel M; Ulenga, Nzovu; Sando, David; Lema, Irene A; Mboggo, Eric; Vaikath, Maria; Koda, Happiness; Lwezaula, Sharon; Hu, Janice; Noor, Ramadhani A; Olofin, Ibironke; Larson, Elysia; Fawzi, Wafaie; Bärnighausen, Till

    2017-02-22

    Home delivery of antiretroviral therapy (ART) by community health workers (CHWs) may improve ART retention by reducing the time burden and out-of-pocket expenditures to regularly attend an ART clinic. In addition, ART home delivery may shorten waiting times and improve quality of care for those in facility-based care by decongesting ART clinics. This trial aims to determine whether ART home delivery for patients who are clinically stable on ART combined with facility-based care for those who are not stable on ART is non-inferior to the standard of care (facility-based care for all ART patients) in achieving and maintaining virological suppression. This is a non-inferiority cluster-randomized trial set in Dar es Salaam, Tanzania. A cluster is one of 48 healthcare facilities with its surrounding catchment area. 24 clusters were randomized to ART home delivery and 24 to the standard of care. The intervention consists of home visits by CHWs to provide counseling and deliver ART to patients who are stable on ART, while the control is the standard of care (facility-based ART and CHW home visits without ART home delivery). In addition, half of the healthcare facilities in each study arm were randomized to standard counseling during home visits (covering family planning, prevention of HIV transmission, and ART adherence), and half to standard plus nutrition counseling (covering food production and dietary advice). The non-inferiority design applies to the endpoints of the ART home delivery trial; the primary endpoint is the proportion of ART patients at a healthcare facility who are virally suppressed at the end of the study period. The margin of non-inferiority for this primary endpoint was set at nine percentage points. As the number of ART patients in sub-Saharan Africa is expected to rise, this trial provides causal evidence on the effectiveness of a home-based care model that could decongest ART clinics and reduce patients' healthcare expenditures. More broadly, this trial will inform the increasing policy interest in task-shifting of chronic disease care from facility- to community-based healthcare workers. ClinicalTrials.gov: NCT02711293 . Registration date: 16 March 2016.

  20. Strategic Defense Initiative Demonstration/Validation Program: Environmental Assessments Summary

    DTIC Science & Technology

    1987-08-01

    TECHNOLOGY TESTS BY FACILITY TECHNOLOGY FACILITY BSTS SSTS GSTS SBI ERIS BM/C 3 Alabama Advanced Research Center A,S,C * California Edwards Air Force Base...Alabama - Advanced Research Center o California - Edwards Air Force Base o Florida - Eglin Air Force Base Kennedy Space Center o Maryland - Harry Diamond...BSTS SSTS GSTS SBI ERIS BM/C 3 Alabama Advanced Research Center A,S,C * California Edwards Air Force Base C Vandenberg Air Force Base/ F (1) F (2) F( 2

  1. Assessment of management policies and practices for occupational exposure to bloodborne pathogens in dialysis facilities.

    PubMed

    Mbaeyi, Chukwuma; Panlilio, Adelisa L; Hobbs, Cynthia; Patel, Priti R; Kuhar, David T

    2012-10-01

    Occupational exposure management is an important element in preventing the transmission of bloodborne pathogens in health care settings. In 2008, the US Centers for Disease Control and Prevention conducted a survey to assess procedures for managing occupational bloodborne pathogen exposures in outpatient dialysis facilities in the United States. A cross-sectional survey of randomly selected outpatient dialysis facilities. 339 outpatient dialysis facilities drawn from the 2006 US end-stage renal disease database. Hospital affiliation (free-standing vs hospital-based facilities), profit status (for-profit vs not-for-profit facilities), and number of health care personnel (≥100 vs <100 health care personnel). Exposures to hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV); provision of HBV and HIV postexposure prophylaxis. We calculated the proportion of facilities reporting occupational bloodborne pathogen exposures and offering occupational exposure management services. We analyzed bloodborne pathogen exposures and provision of postexposure prophylaxis by facility type. Nearly all respondents (99.7%) had written policies and 95% provided occupational exposure management services to health care personnel during the daytime on weekdays, but services were provided infrequently during other periods of the week. Approximately 10%-15% of facilities reported having HIV, HBV, or HCV exposures in health care personnel in the 12 months prior to the survey, but inconsistencies were noted in procedures for managing such exposures. Despite 86% of facilities providing HIV prophylaxis for exposed health care personnel, only 37% designated a primary HIV postexposure prophylaxis regimen. For-profit and free-standing facilities reported fewer exposures, but did not as reliably offer HBV prophylaxis or have a primary HIV postexposure prophylaxis regimen relative to not-for-profit and hospital-based facilities. The survey response rate was low (37%) and familiarity of individuals completing the survey with facility policies or national guidelines could not be ascertained. Significant improvements are required in the implementation of guidelines for managing occupational exposures to bloodborne pathogens in outpatient dialysis facilities. Published by Elsevier Inc.

  2. Is the closest facility the one actually used? An assessment of travel time estimation based on mammography facilities.

    PubMed

    Alford-Teaster, Jennifer; Lange, Jane M; Hubbard, Rebecca A; Lee, Christoph I; Haas, Jennifer S; Shi, Xun; Carlos, Heather A; Henderson, Louise; Hill, Deirdre; Tosteson, Anna N A; Onega, Tracy

    2016-02-18

    Characterizing geographic access depends on a broad range of methods available to researchers and the healthcare context to which the method is applied. Globally, travel time is one frequently used measure of geographic access with known limitations associated with data availability. Specifically, due to lack of available utilization data, many travel time studies assume that patients use the closest facility. To examine this assumption, an example using mammography screening data, which is considered a geographically abundant health care service in the United States, is explored. This work makes an important methodological contribution to measuring access--which is a critical component of health care planning and equity almost everywhere. We analyzed one mammogram from each of 646,553 women participating in the US based Breast Cancer Surveillance Consortium for years 2005-2012. We geocoded each record to street level address data in order to calculate travel time to the closest and to the actually used mammography facility. Travel time between the closest and the actual facility used was explored by woman-level and facility characteristics. Only 35% of women in the study population used their closest facility, but nearly three-quarters of women not using their closest facility used a facility within 5 min of the closest facility. Individuals that by-passed the closest facility tended to live in an urban core, within higher income neighborhoods, or in areas where the average travel times to work was longer. Those living in small towns or isolated rural areas had longer closer and actual median drive times. Since the majority of US women accessed a facility within a few minutes of their closest facility this suggests that distance to the closest facility may serve as an adequate proxy for utilization studies of geographically abundant services like mammography in areas where the transportation networks are well established.

  3. Developing tourism facilities based on geotourism in Silalahi Village, Geopark Toba Caldera

    NASA Astrophysics Data System (ADS)

    Ginting, Nurlisa; Sasmita, Anggun

    2018-03-01

    Toba Caldera is one of the biggest lakes in Indonesia with supervolcano geology phenomenon, and its result amazing natural resources. It makes Toba Lake become the number one tourism in North Sumatera. However, tourism in Toba Lake is still needed development. Geotourism is one of the concept that suitable for this case. It is because geotourism is a new development tourism concept that focuses on the natural and geological phenomenon. Silalahi Village is one of the areas in Toba Caldera that still needs development, especially in tourism facilities sector. This research aims to investigation the facilities concept based on geotourism in Silalahi Village that would be analyzed by three element of tourism facilities namely, accommodation, support facilities and tourism auxiliary facilities. The method used for this research is mixed methods by distributing 100 questionnaires, observations directly to the area and interviews with three informants related parties interested in tourism, such as local people, government, and academics. The data would be processed and analyzed with techniques of exploration. The result shows that the three elements of tourism facilities are still lacking and needs to improve to increase the economy and tourism in the area.

  4. Web-Based Requesting and Scheduling Use of Facilities

    NASA Technical Reports Server (NTRS)

    Yeager, Carolyn M.

    2010-01-01

    Automated User's Training Operations Facility Utilization Request (AutoFUR) is prototype software that administers a Web-based system for requesting and allocating facilities and equipment for astronaut-training classes in conjunction with scheduling the classes. AutoFUR also has potential for similar use in such applications as scheduling flight-simulation equipment and instructors in commercial airplane-pilot training, managing preventive- maintenance facilities, and scheduling operating rooms, doctors, nurses, and medical equipment for surgery. Whereas requesting and allocation of facilities was previously a manual process that entailed examination of documents (including paper drawings) from different sources, AutoFUR partly automates the process and makes all of the relevant information available via the requester s computer. By use of AutoFUR, an instructor can fill out a facility-utilization request (FUR) form on line, consult the applicable flight manifest(s) to determine what equipment is needed and where it should be placed in the training facility, reserve the corresponding hardware listed in a training-hardware inventory database, search for alternative hardware if necessary, submit the FUR for processing, and cause paper forms to be printed. Auto-FUR also maintains a searchable archive of prior FURs.

  5. From Cure to Care: Assessing the Ethical and Professional Learning Needs of Medical Learners in a Care-Based Facility

    ERIC Educational Resources Information Center

    Hall, Pippa; O'Reilly, Jane; Dojeiji, Sue; Blair, Richard; Harley, Anne

    2009-01-01

    The purpose of this study was to assess the ethical and professional learning needs of medical trainees on clinical placements at a care-based facility, as they shifted from acute care to care-based philosophy. Using qualitative data analysis and grounded theory techniques, 12 medical learners and five clinical supervisors were interviewed. Five…

  6. Final Environmental Assessment: Proposed Composite Aircraft Inspection Facilities, Hill Air Force Base, Utah

    DTIC Science & Technology

    2008-10-02

    radiography . Two large inspection bays would each accommodate one F-22 aircraft and robotic x-ray inspection equipment. Six smaller bays would accommodate...large aircraft components (two ultrasonic inspection bays, two laser shearography inspection bays, and two digital radiography inspection bays...Hill Air Force Base, Utah Final Environmental Assessment: Proposed Composite Aircraft Inspection Facilities, Hill Air Force Base, Utah

  7. Provision of family planning services in Tanzania: a comparative analysis of public and private facilities.

    PubMed

    Kakoko, Deodatus C; Ketting, Evert; Kamazima, Switbert R; Ruben, Ruerd

    2012-12-01

    Adherence to the policy guidelines and standards is necessary for family planning services. We compared public and private facilities in terms of provision of family planning services. We analyzed data from health facility questionnaire of the 2006 Tanzania Service Provision Assessment survey, based on 529 health facilities. Majority of public facilities (95.4%) offered family planning services, whereas more than half of private facilities (52.1%) did not offer those. Public facilities were more likely to offer modern contraceptives as compared to private facilities. However, private facilities were more likely to offer counseling on natural methods of family planning [AOR = 2.12 (1.15-3.92), P < or = 0.001]. Public facilities were more likely to report having guidelines or protocols for family planning services and various kinds of visual aids for family planning and STIs when compared to private facilities. This comparative analysis entails the need to enforce the standards of family planning services in Tanzania.

  8. EPA Facility Registry Service (FRS): CAMDBS

    EPA Pesticide Factsheets

    This web feature service contains location and facility identification information from EPA's Facility Registry Service (FRS) for the subset of facilities that link to the Clean Air Markets Division Business System (CAMDBS). Administered by the EPA Clean Air Markets Division, within the Office of Air and Radiation, CAMDBS supports the implementation of market-based air pollution control programs, including the Acid Rain Program and regional programs designed to reduce the transport of ozone. FRS identifies and geospatially locates facilities, sites or places subject to environmental regulations or of environmental interest. Using vigorous verification and data management procedures, FRS integrates facility data from EPA's national program systems, other federal agencies, and State and tribal master facility records and provides EPA with a centrally managed, single source of comprehensive and authoritative information on facilities. This data set contains the subset of FRS integrated facilities that link to CAMDBS facilities once the CAMDBS data has been integrated into the FRS database. Additional information on FRS is available at the EPA website https://www.epa.gov/enviro/facility-registry-service-frs.

  9. Does courtesy bias affect how clients report on objective and subjective measures of family planning service quality? A comparison between facility- and home-based interviews.

    PubMed

    Hameed, Waqas; Ishaque, Muhammad; Gul, Xaher; Siddiqui, Junaid-Ur-Rehman; Hussain, Sharmeen; Hussain, Wajahat; Ahmed, Aftab; Balal, Asma

    2017-01-01

    Despite a general understanding that exit interviews being conducted at service providers' facilities may influence clients' responses favorably to health professionals, there is very little evidence available that demonstrates the extent to which this problem exists. This study aimed at assessing and comparing clients' perceptions of the quality of family planning services and their satisfaction levels between facility- and home-based interviews. A cross-sectional survey was conducted among clients receiving family planning services across three service delivery channels - nongovernmental organization (NGO) clinics, social franchise (SF) centers, and outreach camps. The survey took place from December 2015 to January 2016 in 70 districts across all four provinces of Pakistan. A total of 2,807 clients were interviewed, of whom 1,404 clients were interviewed at health facilities after receiving services and 1,403 were interviewed at their homes within 3 days of method uptake. Overall, we found no significant differences between the characteristics of study participants interviewed at health facilities or at home. The findings suggested that experiences reported in exit surveys at facilities were strongly biased positively. This was true for both experiential (service quality) and perception-based (satisfaction) questions in the context of SF centers, while at NGO clinics the interview location only affected clients' responses regarding service quality. However, in outreach settings, clients are more likely to share bad experiences in exit interviews than in home-based interviews on objectively asked questions (service quality). Our study indicates signs of courtesy bias and possibly the Hawthorne effect in exit interviews. Program implementers could opt for home-based interviews for women receiving services at NGO clinics or SF center, whereas exit interviews could be used in outreach settings.

  10. Does courtesy bias affect how clients report on objective and subjective measures of family planning service quality? A comparison between facility- and home-based interviews

    PubMed Central

    Hameed, Waqas; Ishaque, Muhammad; Gul, Xaher; Siddiqui, Junaid-ur-Rehman; Hussain, Sharmeen; Hussain, Wajahat; Ahmed, Aftab; Balal, Asma

    2017-01-01

    Purpose Despite a general understanding that exit interviews being conducted at service providers’ facilities may influence clients’ responses favorably to health professionals, there is very little evidence available that demonstrates the extent to which this problem exists. This study aimed at assessing and comparing clients’ perceptions of the quality of family planning services and their satisfaction levels between facility- and home-based interviews. Methods A cross-sectional survey was conducted among clients receiving family planning services across three service delivery channels – nongovernmental organization (NGO) clinics, social franchise (SF) centers, and outreach camps. The survey took place from December 2015 to January 2016 in 70 districts across all four provinces of Pakistan. A total of 2,807 clients were interviewed, of whom 1,404 clients were interviewed at health facilities after receiving services and 1,403 were interviewed at their homes within 3 days of method uptake. Results Overall, we found no significant differences between the characteristics of study participants interviewed at health facilities or at home. The findings suggested that experiences reported in exit surveys at facilities were strongly biased positively. This was true for both experiential (service quality) and perception-based (satisfaction) questions in the context of SF centers, while at NGO clinics the interview location only affected clients’ responses regarding service quality. However, in outreach settings, clients are more likely to share bad experiences in exit interviews than in home-based interviews on objectively asked questions (service quality). Conclusion Our study indicates signs of courtesy bias and possibly the Hawthorne effect in exit interviews. Program implementers could opt for home-based interviews for women receiving services at NGO clinics or SF center, whereas exit interviews could be used in outreach settings. PMID:29760573

  11. Public-Private Ventures in Bachelor Quarters: A Solution to the Loss of Military Construction Projects. Volume 1. Findings, Conclusions, and Recommendations

    DTIC Science & Technology

    1990-06-01

    restaurants, and other amenities. Although the food and beverage facilities at the National Medical Center are ample, they are not targeted for the...against including a club and restaurant in the BOQ project. Current on-base food and beverage facilities are sufficient to serve the additional demand that...taxing its capacity. In fact, tlie base has six food and beverage facilities that provide a variety of choices, and adding a seventh in the BOQ would

  12. Nuclotron-Based Ion Collider Facility (nica)

    NASA Astrophysics Data System (ADS)

    Meshkov, I.; Sissakian, A.; Sorin, A.

    2008-09-01

    The project of an ion collider accelerator complex NICA that is under development at JINR is presented. The article is based on the Conceptual Design Report (CDR)1 of the NICA project delivered in January 2008. The article contains NICA facility scheme, the facility operation scenario, its elements parameters, the proposed methods of intense ion beam acceleration and achievement of the required luminosity of the collider. The symmetric mode of the collider operation is considered here and most attention is concentrated on the luminosity provision in collisions of uranium ions (nuclei).

  13. Health care facility-based decontamination of victims exposed to chemical, biological, and radiological materials.

    PubMed

    Koenig, Kristi L; Boatright, Connie J; Hancock, John A; Denny, Frank J; Teeter, David S; Kahn, Christopher A; Schultz, Carl H

    2008-01-01

    Since the US terrorist attacks of September 11, 2001, concern regarding use of chemical, biological, or radiological weapons is heightened. Many victims of such an attack would present directly to health care facilities without first undergoing field decontamination. This article reviews basic tenets and recommendations for health care facility-based decontamination, including regulatory concerns, types of contaminants, comprehensive decontamination procedures (including crowd control, triage, removal of contaminated garments, cleaning of body contaminants, and management of contaminated materials and equipment), and a discussion of methods to achieve preparedness.

  14. Space transportation node - The Atrium Facility

    NASA Technical Reports Server (NTRS)

    Kennedy, Kriss J.

    1990-01-01

    A conceptual design for a space transportation node is presented with a view to the fulfilment of assembly platform support requirements associated with a lunar transportation system. This 'Atrium Facility', which will support lunar base activities before, during, and after the lunar base buildup phase, encompasses a central assembly area surrounded by hangars and workstation platforms; six permanent crewmembers will be supported, as well as four to six transient lunar and Space Shuttle crewmembers. The Atrium Facility dry mass of nearly 320,000 kg excludes cryogenic propellant stowage and the traslunar vehicle envisioned for transportation.

  15. Radiological performance assessment for the E-Area Vaults Disposal Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cook, J.R.

    This report is the first revision to ``Radiological Performance Assessment for the E-Area Vaults Disposal Facility, Revision 0'', which was issued in April 1994 and received conditional DOE approval in September 1994. The title of this report has been changed to conform to the current name of the facility. The revision incorporates improved groundwater modeling methodology, which includes a large data base of site specific geotechnical data, and special Analyses on disposal of cement-based wasteforms and naval wastes, issued after publication of Revision 0.

  16. Medicare and Medicaid programs; fire safety requirements for certain health care facilities; amendment. Interim final rule with comment period.

    PubMed

    2005-03-25

    This interim final rule with comment period adopts the substance of the April 15, 2004 temporary interim amendment (TIA) 00-1 (101), Alcohol Based Hand Rub Solutions, an amendment to the 2000 edition of the Life Safety Code, published by the National Fire Protection Association (NFPA). This amendment will allow certain health care facilities to place alcohol-based hand rub dispensers in egress corridors under specified conditions. This interim final rule with comment period also requires that nursing facilities install smoke detectors in resident rooms and public areas if they do not have a sprinkler system installed throughout the facility or a hard-wired smoke detection system in those areas.

  17. Availability of Youth Services in U.S. Mental Health Treatment Facilities.

    PubMed

    Cummings, Janet R; Case, Brady G; Ji, Xu; Marcus, Steven C

    2016-09-01

    Despite concern about access to mental health (MH) services for youth, little is known about the specialty treatment infrastructure serving this population. We used national data to examine which types of MH treatment facilities (hospital- and community-based) were most likely to offer youth services and which types of communities were most likely to have this infrastructure. Larger (p < 0.001) and privately owned (p < 0.001) facilities were more likely to offer youth services. Rural counties, counties in which a majority of residents were nonwhite, and/or counties with a higher percentage of uninsured residents were less likely to have a community-based MH treatment facility that served youth (p < 0.001).

  18. The Size and Scope of Collegiate Athletic Training Facilities and Staffing.

    PubMed

    Gallucci, Andrew R; Petersen, Jeffrey C

    2017-08-01

      Athletic training facilities have been described in terms of general design concepts and from operational perspectives. However, the size and scope of athletic training facilities, along with staffing at different levels of intercollegiate competition, have not been quantified.   To define the size and scope of athletic training facilities and staffing levels at various levels of intercollegiate competition. To determine if differences existed in facilities (eg, number of facilities, size of facilities) and staffing (eg, full time, part time) based on the level of intercollegiate competition.   Cross-sectional study.   Web-based survey.   Athletic trainers (ATs) who were knowledgeable about the size and scope of athletic training programs.   Athletic training facility size in square footage; the AT's overall facility satisfaction; athletic training facility component spaces, including satellite facilities, game-day facilities, offices, and storage areas; and staffing levels, including full-time ATs, part-time ATs, and undergraduate students.   The survey was completed by 478 ATs (response rate = 38.7%) from all levels of competition. Sample means for facilities were 3124.7 ± 4425 ft 2 (290.3 ± 411 m 2 ) for the central athletic training facility, 1013 ± 1521 ft 2 (94 ± 141 m 2 ) for satellite athletic training facilities, 1272 ± 1334 ft 2 (118 ± 124 m 2 ) for game-day athletic training facilities, 388 ± 575 ft 2 (36 ± 53 m 2 ) for athletic training offices, and 424 ± 884 ft 2 (39 ± 82 m 2 ) for storage space. Sample staffing means were 3.8 ± 2.5 full-time ATs, 1.6 ± 2.5 part-time ATs, 25 ± 17.6 athletic training students, and 6.8 ± 7.2 work-study students. Division I schools had greater resources in multiple categories (P < .001). Differences among other levels of competition were not as well defined. Expansion or renovation of facilities in recent years was common, and almost half of ATs reported that upgrades have been approved for the near future.   This study provides benchmark descriptive data on athletic training staffing and facilities. The results (1) suggest that the ATs were satisfied with their facilities and (2) highlight the differences in resources among competition levels.

  19. Strategic Defense Initiative Demonstration/Validation Program Environmental Assessment. Space-Based Surveillance and Tracking System (SSTS),

    DTIC Science & Technology

    1987-08-01

    take place in both contractor and government facilities. The on-orbit evaluation could utilize modified launch facilities depending on the launch...technological issues : o Telescope Optics: Verify that the distortions associated vith large optical elements satisfy detection and tracking requirements; verify...Validation program vould be car- ried out at contractor facilities that 1’ave not been identified and at six government facilities (Arnold Engineering

  20. Gemini Observatory base facility operations: systems engineering process and lessons learned

    NASA Astrophysics Data System (ADS)

    Serio, Andrew; Cordova, Martin; Arriagada, Gustavo; Adamson, Andy; Close, Madeline; Coulson, Dolores; Nitta, Atsuko; Nunez, Arturo

    2016-08-01

    Gemini North Observatory successfully began nighttime remote operations from the Hilo Base Facility control room in November 2015. The implementation of the Gemini North Base Facility Operations (BFO) products was a great learning experience for many of our employees, including the author of this paper, the BFO Systems Engineer. In this paper we focus on the tailored Systems Engineering processes used for the project, the various software tools used in project support, and finally discuss the lessons learned from the Gemini North implementation. This experience and the lessons learned will be used both to aid our implementation of the Gemini South BFO in 2016, and in future technical projects at Gemini Observatory.

  1. Fuel-Flexible Gas Turbine Combustor Flametube Facility

    NASA Technical Reports Server (NTRS)

    Little, James E.; Nemets, Stephen A.; Tornabene, Robert T.; Smith, Timothy D.; Frankenfield, Bruce J.; Manning, Stephen D.; Thompson, William K.

    2004-01-01

    Facility modifications have been completed to an existing combustor flametube facility to enable testing with gaseous hydrogen propellants at the NASA Glenn Research Center. The purpose of the facility is to test a variety of fuel nozzle and flameholder hardware configurations for use in aircraft combustors. Facility capabilities have been expanded to include testing with gaseous hydrogen, along with the existing hydrocarbon-based jet fuel. Modifications have also been made to the facility air supply to provide heated air up to 350 psig, 1100 F, and 3.0 lbm/s. The facility can accommodate a wide variety of flametube and fuel nozzle configurations. Emissions and performance data are obtained via a variety of gas sample probe configurations and emissions measurement equipment.

  2. The design and implementation of the Technical Facilities Controller (TFC) for the Goldstone deep space communications complex

    NASA Technical Reports Server (NTRS)

    Killian, D. A.; Menninger, F. J.; Gorman, T.; Glenn, P.

    1988-01-01

    The Technical Facilities Controller is a microprocessor-based energy management system that is to be implemented in the Deep Space Network facilities. This system is used in conjunction with facilities equipment at each of the complexes in the operation and maintenance of air-conditioning equipment, power generation equipment, power distribution equipment, and other primary facilities equipment. The implementation of the Technical Facilities Controller was completed at the Goldstone Deep Space Communications Complex and is now operational. The installation completed at the Goldstone Complex is described and the utilization of the Technical Facilities Controller is evaluated. The findings will be used in the decision to implement a similar system at the overseas complexes at Canberra, Australia, and Madrid, Spain.

  3. [Interdisciplinary Cooperation as a Characteristic of Successful Rehabilitation Facilities--Results from the Project MeeR].

    PubMed

    Kleineke, V; Stamer, M; Zeisberger, M; Brandes, I; Meyer, T

    2015-08-01

    To determine if there is a difference between successful and less successful rehabilitation facilities concerning their extent and quality of interdisciplinary cooperation? This analysis is part of the project MeeR, that aims to identify characteristics of rehabilitation facilities related to successful rehabilitation. 6 facilities were recruited based on a quantitative analysis; 3 facilities that ranked as above average and 3 as below average in terms of their success in rehabilitating patients. Comprehensive qualitative data were collected on these 6 facilities. In above average rehabilitation facilities, the extent of interdisciplinary cooperation was higher than in below average facilities; the position of the medical profession was less dominant and there was a wider access to team meetings. Promotion of interdisciplinary cooperation is an important component for the improvement of the success of rehabilitation facilities. © Georg Thieme Verlag KG Stuttgart · New York.

  4. Various Approaches for Targeting Quasar Candidates

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Zhao, Y.

    2015-09-01

    With the establishment and development of space-based and ground-based observational facilities, the improvement of scientific output of high-cost facilities is still a hot issue for astronomers. The discovery of new and rare quasars attracts much attention. Different methods to select quasar candidates are in bloom. Among them, some are based on color cuts, some are from multiwavelength data, some rely on variability of quasars, some are based on data mining, and some depend on ensemble methods.

  5. Studies of Plasma Instability Processes Excited by Ground Based High Power HF (Heating) Facilities

    DTIC Science & Technology

    2001-04-01

    and Megill, 1974; Carlson, 1974; Bernhardt et al., 1989). During the last years new interesting results have been obtained at HAARP facility (Peterson...Haslett and Megill, 1974; Carlson, 1974; Bernhardt et al., 1989). During the last years new interesting results have been obtained at HAARP facility

  6. Comparative Costs and Staffing Report for College and University Facilities, 1993-94.

    ERIC Educational Resources Information Center

    Silberman, Gil, Ed.; Glazner, Steve, Ed.

    This report presents comparative data on facility management costs and staffing based on responses from 516 U.S. postsecondary educational facilities during 1993-94. It lists statistics from both private and public institutions, beginning with statistical reductions presenting the survey response tally, institutional profiles, and mean costs per…

  7. School Facilities Funding and Capital-Outlay Distribution in the States

    ERIC Educational Resources Information Center

    Duncombe, William; Wang, Wen

    2009-01-01

    Traditionally, financing the construction of school facilities has been a local responsibility. In the past several decades, states have increased their support for school facilities. Using data collected from various sources, this study first classifies the design of capital aid programs in all 50 states into various categories based on the scope…

  8. 21 CFR 900.16 - Appeals of denials of certification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... accreditation body. Appeals for facilities that have failed to become accredited are governed by the procedures... facility will not permit inspections or provide access to records or information in a timely fashion; or (3... accreditation body, FDA shall provide the facility with a statement of the grounds on which the denial is based...

  9. 21 CFR 900.16 - Appeals of denials of certification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... accreditation body. Appeals for facilities that have failed to become accredited are governed by the procedures... facility will not permit inspections or provide access to records or information in a timely fashion; or (3... accreditation body, FDA shall provide the facility with a statement of the grounds on which the denial is based...

  10. Planning for Future Forms of Education: Towards an Educational and Educational Facilities Planning Model.

    ERIC Educational Resources Information Center

    Leu, Donald J.

    The author provides an overview and conceptualization of the total educational and educational facility planning process. The presentation attempts to provide a simple practical outline for local planners, so they may actively engage in relevant educational facility planning, and a common conceptual base, so the various components of Project…

  11. 78 FR 36744 - Diamond Sawblades and Parts Thereof From the People's Republic of China: Preliminary Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... management, production facilities, supplier relationships, and customer base.\\5\\ While no single factor or... significant changes to management, production facilities, supplier relationships, and customers. As a result..., production facilities, and customer/ supplier relationships have not changed as a result of the name change...

  12. Proposed Capital Program 1970-1975, the School District of Philadelphia.

    ERIC Educational Resources Information Center

    Philadelphia School District, PA.

    This report presents the School District of Philadelphia's long-range plan for school facilities and, based upon it, a capital program for the fiscal years 1970 through 1975. Present conditions are reviewed, citing the "facility gap" and indicating future needs. The plan for school facilities is presented specifying--(1) the educational basis of…

  13. Comparative Costs and Staffing Report for Educational Facilities, 1997-1998.

    ERIC Educational Resources Information Center

    Glazner, Steve, Ed.

    This report presents comparative data on facility management costs and staffing based on responses from 193 U.S. postsecondary educational facilities and K-12 institutions during 1997-98. It also lists data from both private and public institutions. Section 1 contains general data on the survey response tally and institutional profiles listed by…

  14. Use of the Homeland-Defense Operational Planning System (HOPS) for Emergency Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Durling, Jr., R L; Price, D E

    2005-12-16

    The Homeland-Defense Operational Planning System (HOPS), is a new operational planning tool leveraging Lawrence Livermore National Laboratory's expertise in weapons systems and in sparse information analysis to support the defense of the U.S. homeland. HOPS provides planners with a basis to make decisions to protect against acts of terrorism, focusing on the defense of facilities critical to U.S. infrastructure. Criticality of facilities, structures, and systems is evaluated on a composite matrix of specific projected casualty, economic, and sociopolitical impact bins. Based on these criteria, significant unidentified vulnerabilities are identified and secured. To provide insight into potential successes by malevolent actors,more » HOPS analysts strive to base their efforts mainly on unclassified open-source data. However, more cooperation is needed between HOPS analysts and facility representatives to provide an advantage to those whose task is to defend these facilities. Evaluated facilities include: refineries, major ports, nuclear power plants and other nuclear licensees, dams, government installations, convention centers, sports stadiums, tourist venues, and public and freight transportation systems. A generalized summary of analyses of U.S. infrastructure facilities will be presented.« less

  15. Risk Assessment Using The Homeland-Defense Operational Planning System (HOPS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Price, D E; Durling, R L

    2005-10-10

    The Homeland-Defense Operational Planning System (HOPS), is a new operational planning tool leveraging Lawrence Livermore National Laboratory's expertise in weapons systems and in sparse information analysis to support the defense of the U.S. homeland. HOPS provides planners with a basis to make decisions to protect against acts of terrorism, focusing on the defense of facilities critical to U.S. infrastructure. Criticality of facilities, structures, and systems is evaluated on a composite matrix of specific projected casualty, economic, and sociopolitical impact bins. Based on these criteria, significant unidentified vulnerabilities are identified and secured. To provide insight into potential successes by malevolent actors,more » HOPS analysts strive to base their efforts mainly on unclassified open-source data. However, more cooperation is needed between HOPS analysts and facility representatives to provide an advantage to those whose task is to defend these facilities. Evaluated facilities include: refineries, major ports, nuclear power plants and other nuclear licensees, dams, government installations, convention centers, sports stadiums, tourist venues, and public and freight transportation systems. A generalized summary of analyses of U.S. infrastructure facilities will be presented.« less

  16. Correspondence regarding 'Assefa Y, et al., BMC Health Services Research. 2011; 11 (1):81 and 2014; 14(1):45': The Positive-Deviance approach for translating evidence into practice to improve patient retention in HIV care.

    PubMed

    Assefa, Yibeltal; Hill, Peter S; Kloos, Helmut; Ooms, Gorik; Van Damme, Wim

    2018-03-21

    The purpose of this correspondence is to describe how the positive-deviance approach can be used to translate evidence into practice, based on successive studies conducted in Ethiopia. In earlier studies, it was identified that retention in antiretroviral treatment care was variable across health facilities; and, seeking compliance across facilities, a framework was developed based on the practices of those positive-deviant health facilities, where performance was noted to be markedly better. It was found that the positive deviance approach was effective in facilitating the transfer of innovative practices (using different mechanisms) from positive-deviant health facilities to negative-deviant health facilities. As a result, the variability in retention in care across health facilities narrowed over time, increasing from 83 to 96% in 2007/8 to 95-97% in 2013/14. In conclusion, the positive-deviance approach is a valuable tool to translate evidence into practice, spread good practices, and help achieving universal health coverage.

  17. Observation of Neutron Skyshine from an Accelerator Based Neutron Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Franklyn, C. B.

    2011-12-13

    A key feature of neutron based interrogation systems is the need for adequate provision of shielding around the facility. Accelerator facilities adapted for fast neutron generation are not necessarily suitably equipped to ensure complete containment of the vast quantity of neutrons generated, typically >10{sup 11} n{center_dot}s{sup -1}. Simulating the neutron leakage from a facility is not a simple exercise since the energy and directional distribution can only be approximated. Although adequate horizontal, planar shielding provision is made for a neutron generator facility, it is sometimes the case that vertical shielding is minimized, due to structural and economic constraints. It ismore » further justified by assuming the atmosphere above a facility functions as an adequate radiation shield. It has become apparent that multiple neutron scattering within the atmosphere can result in a measurable dose of neutrons reaching ground level some distance from a facility, an effect commonly known as skyshine. This paper describes a neutron detection system developed to monitor neutrons detected several hundred metres from a neutron source due to the effect of skyshine.« less

  18. Evaluating the impact of the community-based health planning and services initiative on uptake of skilled birth care in Ghana.

    PubMed

    Johnson, Fiifi Amoako; Frempong-Ainguah, Faustina; Matthews, Zoe; Harfoot, Andrew J P; Nyarko, Philomena; Baschieri, Angela; Gething, Peter W; Falkingham, Jane; Atkinson, Peter M

    2015-01-01

    The Community-based Health Planning and Services (CHPS) initiative is a major government policy to improve maternal and child health and accelerate progress in the reduction of maternal mortality in Ghana. However, strategic intelligence on the impact of the initiative is lacking, given the persistant problems of patchy geographical access to care for rural women. This study investigates the impact of proximity to CHPS on facilitating uptake of skilled birth care in rural areas. Data from the 2003 and 2008 Demographic and Health Survey, on 4,349 births from 463 rural communities were linked to georeferenced data on health facilities, CHPS and topographic data on national road-networks. Distance to nearest health facility and CHPS was computed using the closest facility functionality in ArcGIS 10.1. Multilevel logistic regression was used to examine the effect of proximity to health facilities and CHPS on use of skilled care at birth, adjusting for relevant predictors and clustering within communities. The results show that a substantial proportion of births continue to occur in communities more than 8 km from both health facilities and CHPS. Increases in uptake of skilled birth care are more pronounced where both health facilities and CHPS compounds are within 8 km, but not in communities within 8 km of CHPS but lack access to health facilities. Where both health facilities and CHPS are within 8 km, the odds of skilled birth care is 16% higher than where there is only a health facility within 8km. Where CHPS compounds are set up near health facilities, there is improved access to care, demonstrating the facilitatory role of CHPS in stimulating access to better care at birth, in areas where health facilities are accessible.

  19. Evaluating the Impact of the Community-Based Health Planning and Services Initiative on Uptake of Skilled Birth Care in Ghana

    PubMed Central

    Johnson, Fiifi Amoako; Frempong-Ainguah, Faustina; Matthews, Zoe; Harfoot, Andrew J. P.; Nyarko, Philomena; Baschieri, Angela; Gething, Peter W.; Falkingham, Jane; Atkinson, Peter M.

    2015-01-01

    Background The Community-based Health Planning and Services (CHPS) initiative is a major government policy to improve maternal and child health and accelerate progress in the reduction of maternal mortality in Ghana. However, strategic intelligence on the impact of the initiative is lacking, given the persistant problems of patchy geographical access to care for rural women. This study investigates the impact of proximity to CHPS on facilitating uptake of skilled birth care in rural areas. Methods and Findings Data from the 2003 and 2008 Demographic and Health Survey, on 4,349 births from 463 rural communities were linked to georeferenced data on health facilities, CHPS and topographic data on national road-networks. Distance to nearest health facility and CHPS was computed using the closest facility functionality in ArcGIS 10.1. Multilevel logistic regression was used to examine the effect of proximity to health facilities and CHPS on use of skilled care at birth, adjusting for relevant predictors and clustering within communities. The results show that a substantial proportion of births continue to occur in communities more than 8 km from both health facilities and CHPS. Increases in uptake of skilled birth care are more pronounced where both health facilities and CHPS compounds are within 8 km, but not in communities within 8 km of CHPS but lack access to health facilities. Where both health facilities and CHPS are within 8 km, the odds of skilled birth care is 16% higher than where there is only a health facility within 8km. Conclusion Where CHPS compounds are set up near health facilities, there is improved access to care, demonstrating the facilitatory role of CHPS in stimulating access to better care at birth, in areas where health facilities are accessible. PMID:25789874

  20. 78 FR 27417 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ..., Washington, DC 20593-0001; (202) 475- 5609; NASA: Mr. Frank T. Bellinger, Facilities Engineering Division...: Unutilized Comments: Off-site removal; 1,836 sf.; storage; 60 months vacant; lead-based paint; very poor....; storage; 60 months vacant; very poor conditions; lead-based paint; repairs a must; rodents w/Hanta virus...

  1. 76 FR 70118 - Notice of Public Meetings for the Draft Environmental Impact Statement for Basing of MV-22 and H...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... and parking apron improvements; construction of additional bachelor enlisted quarters (BEQs... MCB Hawaii Kaneohe Bay, types of basing facilities that are required, improvements at training areas... construction, replacement, and renovation of facilities at MCB Hawaii Kaneohe Bay, and include improvements to...

  2. The Successes and Struggles of Closing a Facility-Based Employment Service.

    ERIC Educational Resources Information Center

    Butterworth, John; Fesko, Sheila Lynch

    1999-01-01

    This brief paper reports on an evaluation of 10 community rehabilitation providers, six that successfully closed a facility-based program between 1989 and 1994, and four who are currently involved in a change process. Data collection consisted of participant observation, in-depth interviews, and document analysis. Findings indicated: (1)…

  3. Event simulation based on three-fluid hydrodynamics for collisions at energies available at the Dubna Nuclotron-based Ion Collider Facility and at the Facility for Antiproton and Ion Research in Darmstadt

    NASA Astrophysics Data System (ADS)

    Batyuk, P.; Blaschke, D.; Bleicher, M.; Ivanov, Yu. B.; Karpenko, Iu.; Merts, S.; Nahrgang, M.; Petersen, H.; Rogachevsky, O.

    2016-10-01

    We present an event generator based on the three-fluid hydrodynamics approach for the early stage of the collision, followed by a particlization at the hydrodynamic decoupling surface to join to a microscopic transport model, ultrarelativistic quantum molecular dynamics, to account for hadronic final-state interactions. We present first results for nuclear collisions of the Facility for Antiproton and Ion Research-Nuclotron-based Ion Collider Facility energy scan program (Au+Au collisions, √{sN N}=4 -11 GeV ). We address the directed flow of protons and pions as well as the proton rapidity distribution for two model equations of state, one with a first-order phase transition and the other with a crossover-type softening at high densities. The new simulation program has the unique feature that it can describe a hadron-to-quark matter transition which proceeds in the baryon stopping regime that is not accessible to previous simulation programs designed for higher energies.

  4. Revealed access to haemodialysis facilities in northeastern Iran: Factors that matter in rural and urban areas.

    PubMed

    Kiani, Behzad; Bagheri, Nasser; Tara, Ahmad; Hoseini, Benyamin; Tabesh, Hamed; Tara, Mahmood

    2017-11-07

    Poor access to haemodialysis facilities is associated with high mortality and morbidity rates. This study investigated factors affecting revealed access to the haemodialysis facilities considering patients living in rural and urban areas without any haemodialysis facility (Group A) and those living urban areas with haemodialysis facilities (Group B). This study is based on selfreported Actual Access Time (AAT) to referred haemodialysis facilities and other information regarding travel to haemodialysis facilities from patients. All significant variables on univariate analysis were entered into a univariate general linear model in order to identify factors associated with AAT. Both spatial (driving time and distance) and non-spatial factors (sex, income level, caregivers, transportation mode, education level, ethnicity and personal vehicle ownership) influenced the revealed access identified in Group A. The non-spatial factors for Group B patients were the same as for Group A, but no spatial factor was identified in Group B. It was found that accessibility is strongly underestimated when driving time is chosen as accessibility measure to haemodialysis facilities. Analysis of revealed access determinants provides policymakers with an appropriate decision base for making appropriate decisions and finding solutions to decrease the access time for patients under haemodialysis therapy. Driving time alone is not a good proxy for measuring access to haemodialysis facilities as there are many other potential obstacles, such as women's special travel problems, poor other transportation possibilities, ethnicity disparities, low education levels, low caregiver status and low-income.

  5. The effect of on-site and outreach-based needle and syringe programs in people who inject drugs in Kermanshah, Iran.

    PubMed

    Nazari, Seyed Saeed Hashemi; Noroozi, Mehdi; Soori, Hamid; Noroozi, Alireza; Mehrabi, Yadollah; Hajebi, Ahmad; Sharifi, Hamid; Higgs, Peter; Mirzazadeh, Ali

    2016-01-01

    Needle and syringe programs (NSPs) are widely used to reduce harms associated with drug injecting. This study assessed the effect of facility-based (on-site services at drop-in centre) and outreach models of NSP on injection risk behaviours. Self-reported data from 455 people who injected drugs (PWID) during 2014 in Kermanshah, Iran, were examined to measure demographic characteristics and risk behaviors. Self-reported and program data were also assessed to identify their main source of injection equipment. Participants were divided into three sub-groups: facility-based NSP users, outreach NSP users and non-users (comparison group). Coarsened exact matching was used to make the three groups statistically equivalent based on age, place of residence, education and income, and groups were compared regarding the proportion of borrowing or lending of syringes/cookers, reusing syringes and recent HIV testing. Overall, 76% of participants reported any NSP service use during the two months prior to interview. Only 23% (95%CI: 17-27) reported outreach NSP as their main source of syringes. Using facility-based NSP significantly decreased recent syringe borrowing (OR: 0.27, 95%CI: 0.10-0.70), recent syringe reuse (OR: 0.38, 95%CI: 0.23-0.68) and increased recent HIV testing (OR: 2.60, 95%CI: 1.48-4.56). Similar effects were observed among outreach NSP users; in addition, the outreach NSP model significantly reduced the chance of lending syringes (OR: 0.31, 95%CI: 0.15-0.60), compared to facility-based NSP (OR: 1.25, 95%CI: 0.74-2.17). These findings suggest that the outreach NSP model is as effective as facility-based NSP in reducing injection risk behaviours and increasing the rate of HIV testing. Outreach NSP was even more effective than facility-based in reducing the lending of syringes to others. Scaling up outreach NSP is an effective intervention to further reduce transmission of HIV via needle sharing. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Implementation of Grid Tier 2 and Tier 3 facilities on a Distributed OpenStack Cloud

    NASA Astrophysics Data System (ADS)

    Limosani, Antonio; Boland, Lucien; Coddington, Paul; Crosby, Sean; Huang, Joanna; Sevior, Martin; Wilson, Ross; Zhang, Shunde

    2014-06-01

    The Australian Government is making a AUD 100 million investment in Compute and Storage for the academic community. The Compute facilities are provided in the form of 30,000 CPU cores located at 8 nodes around Australia in a distributed virtualized Infrastructure as a Service facility based on OpenStack. The storage will eventually consist of over 100 petabytes located at 6 nodes. All will be linked via a 100 Gb/s network. This proceeding describes the development of a fully connected WLCG Tier-2 grid site as well as a general purpose Tier-3 computing cluster based on this architecture. The facility employs an extension to Torque to enable dynamic allocations of virtual machine instances. A base Scientific Linux virtual machine (VM) image is deployed in the OpenStack cloud and automatically configured as required using Puppet. Custom scripts are used to launch multiple VMs, integrate them into the dynamic Torque cluster and to mount remote file systems. We report on our experience in developing this nation-wide ATLAS and Belle II Tier 2 and Tier 3 computing infrastructure using the national Research Cloud and storage facilities.

  7. How reliable are odour assessments?

    PubMed

    Bokowa, A; Beukes, J A

    2012-01-01

    This paper will demonstrate the differences found in odour test results, when odour sampling is performed at the same sources by two different consultants. By examining two case studies, this paper will highlight that the difference between the results can be significant. Both studies are based on odour sampling programs determining the odour removal efficiency of odour control units installed at two different facilities: a pet food facility and an oil/grease recycling facility. The first study is based on odour measurements at the inlet and outlet of the unit installed by Applied Plasma Physics AS at the pet food facility. Odour assessments were performed by two separate consultants at the same time. The second study is based on testing of the odour removal effectiveness of two units: a scrubber and a biofilter at an oil/grease recycling facility. During this study two odour sampling programs were performed by two consultants at different times, but under the same process conditions. This paper will show how varying results can play a role in choosing the adequate odour control technologies. The final results suggest that although, an odour control unit may appear to be insufficient, it actually is successful at removing the odours.

  8. Healthcare-seeking Behaviour for Common Infectious Disease-related Illnesses in Rural Kenya: A Community-based House-to-house Survey

    PubMed Central

    Flannery, Brendan; Onyango, Bernard; Larson, Charles; Alaii, Jane; Zhang, Xingyou; Hamel, Mary J.; Breiman, Robert F.; Feikin, Daniel R.

    2011-01-01

    Community surveys of healthcare-use determine the proportion of illness episodes not captured by health facility-based surveillance, the methodology used most commonly to estimate the burden of disease in Africa. A cross-sectional survey of households with children aged less than five years was conducted in 35 of 686 census enumeration areas in rural Bondo district, western Kenya. Healthcare sought for acute episodes of diarrhoea or fever in the past two weeks or pneumonia in the past year was evaluated. Factors associa-ted with healthcare-seeking were analyzed by logistic regression accounting for sample design. In total, 6,223 residents of 981 households were interviewed. Of 1,679 children aged less than five years, 233 (14%) had diarrhoea, and 736 (44%) had fever during the past two weeks; care at health facilities was sought for one-third of these episodes. Pneumonia in the past year was reported for 64 (4%) children aged less than five years; 88% sought healthcare at any health facility and 48% at hospitals. Seeking healthcare at health facilities was more likely for children from households with higher socioeconomic status and with more symptoms of severe illness. Health facility and hospital-based surveillance would underestimate the burden of disease substantially in rural western Kenya. Seeking healthcare at health facilities and hospitals varied by syndrome, severity of illness, and characteristics of the patient. PMID:21528791

  9. Metrics for Success: Strategies for Enabling Core Facility Performance and Assessing Outcomes

    PubMed Central

    Hockberger, Philip E.; Meyn, Susan M.; Nicklin, Connie; Tabarini, Diane; Auger, Julie A.

    2016-01-01

    Core Facilities are key elements in the research portfolio of academic and private research institutions. Administrators overseeing core facilities (core administrators) require assessment tools for evaluating the need and effectiveness of these facilities at their institutions. This article discusses ways to promote best practices in core facilities as well as ways to evaluate their performance across 8 of the following categories: general management, research and technical staff, financial management, customer base and satisfaction, resource management, communications, institutional impact, and strategic planning. For each category, we provide lessons learned that we believe contribute to the effective and efficient overall management of core facilities. If done well, we believe that encouraging best practices and evaluating performance in core facilities will demonstrate and reinforce the importance of core facilities in the research and educational mission of institutions. It will also increase job satisfaction of those working in core facilities and improve the likelihood of sustainability of both facilities and personnel. PMID:26848284

  10. Metrics for Success: Strategies for Enabling Core Facility Performance and Assessing Outcomes.

    PubMed

    Turpen, Paula B; Hockberger, Philip E; Meyn, Susan M; Nicklin, Connie; Tabarini, Diane; Auger, Julie A

    2016-04-01

    Core Facilities are key elements in the research portfolio of academic and private research institutions. Administrators overseeing core facilities (core administrators) require assessment tools for evaluating the need and effectiveness of these facilities at their institutions. This article discusses ways to promote best practices in core facilities as well as ways to evaluate their performance across 8 of the following categories: general management, research and technical staff, financial management, customer base and satisfaction, resource management, communications, institutional impact, and strategic planning. For each category, we provide lessons learned that we believe contribute to the effective and efficient overall management of core facilities. If done well, we believe that encouraging best practices and evaluating performance in core facilities will demonstrate and reinforce the importance of core facilities in the research and educational mission of institutions. It will also increase job satisfaction of those working in core facilities and improve the likelihood of sustainability of both facilities and personnel.

  11. Federal Facilities (Executive Offices) Sector (NAICS 921110)

    EPA Pesticide Factsheets

    Find EPA regulatory information for federal facilities (NAICS 92), including information on base closures and transfers, hazardous waste, military munitions, perchorlate, environmentally preferable purchasing and comprehensive procurement guidelines

  12. A Methodology for Conducting Space Utilization Studies within Department of Defense Medical Facilities

    DTIC Science & Technology

    1992-07-01

    database programs, such as dBase or Microsoft Excell, to yield statistical reports that can profile the health care facility . Ladeen (1989) feels that the...service specific space status report would be beneficial to the specific service(s) under study, it would not provide sufficient data for facility -wide...change in the Master Space Plan. The revised methodology also provides a mechanism and forum for spuce management education within the facility . The

  13. China’s Military Support Facility in Djibouti: The Economic and Security Dimensions of China’s First Overseas Base

    DTIC Science & Technology

    2017-07-01

    Cleared for Public Release China’s Military Support Facility in Djibouti: The Economic and Security Dimensions of China’s...paper provides a preliminary look at the origins of China’s military support facility in Djibouti. It explores the evolution of the economic and security...military facilities abroad. It also assesses the implications of the growing economic and military ties between the two countries for the United

  14. Autonomous Electrothermal Facility for Oil Recovery Intensification Fed by Wind Driven Power Unit

    NASA Astrophysics Data System (ADS)

    Belsky, Aleksey A.; Dobush, Vasiliy S.

    2017-10-01

    This paper describes the structure of autonomous facility fed by wind driven power unit for intensification of viscous and heavy crude oil recovery by means of heat impact on productive strata. Computer based service simulation of this facility was performed. Operational energy characteristics were obtained for various operational modes of facility. The optimal resistance of heating element of the downhole heater was determined for maximum operating efficiency of wind power unit.

  15. Are park proximity and park features related to park use and park-based physical activity among adults? Variations by multiple socio-demographic characteristics.

    PubMed

    Kaczynski, Andrew T; Besenyi, Gina M; Stanis, Sonja A Wilhelm; Koohsari, Mohammad Javad; Oestman, Katherine B; Bergstrom, Ryan; Potwarka, Luke R; Reis, Rodrigo S

    2014-12-06

    Parks are valuable resources for physical activity (PA) given their widespread availability and low cost to maintain and use. Both proximity to parks and the availability of particular features are important correlates of PA. However, few studies have explored multiple measures of proximity simultaneously or the specific facilities associated with park use and park-based PA among adults, let alone differences across socio-demographic characteristics. The purpose of this study was to examine associations between park proximity and park facilities and adults' park use and park-based PA, while also exploring differences by gender, age, race, and income. Data on monthly park use and weekly amount of PA undertaken in parks were collected via a mail survey of adults from randomly-selected households (n = 893) in Kansas City, Missouri (KCMO) in 2010-2011. Three measures of park proximity were calculated within 1 mile of participating households: distance to the closest park, number of parks, and total park area. All parks in KCMO were audited using the Community Park Audit Tool to determine the availability of 14 park facilities within 1 mile of each participant (e.g., trail, playground, tennis court). Multilevel logistic regression was used to examine the relationship between each of park use and park-based PA and 1) three measures of park proximity, and 2) the availability of 14 park facilities within 1 mile of participants. Separate analyses were conducted by gender, age, race, and income, while controlling for all socio-demographic characteristics and BMI. Across all sub-samples, distance to the closest park was not significantly related to either park use or park-based PA. However, numerous significant associations were found for the relationship of number of parks and amount of park space within 1 mile with both outcomes. As well, diverse facilities were associated with park use and park-based PA. For both park proximity and facilities, the significant relationships varied widely across gender, age, race, and income groups. Both park proximity and park facilities are related to park use and park-based PA. Understanding how such associations vary across demographic groups is important in planning for activity-friendly parks that are responsive to the needs of neighborhood residents.

  16. Spatial distribution of emergency obstetric and newborn care services in Ghana: Using the evidence to plan interventions.

    PubMed

    Bosomprah, Samuel; Tatem, Andrew J; Dotse-Gborgbortsi, Winfred; Aboagye, Patrick; Matthews, Zoe

    2016-01-01

    To provide clear policy directions for gaps in the provision of signal function services and sub-regions requiring priority attention using data from the 2010 Ghana Emergency Obstetric and Newborn Care (EmONC) survey. Using 2010 survey data, the fraction of facilities with only one or two signal functions missing was calculated for each facility type and EmONC designation. Thematic maps were used to provide insight into inequities in service provision. Of 1159 maternity facilities, 89 provided all the necessary basic or comprehensive EmONC signal functions 3months prior to the 2010 survey. Only 21% of facility-based births were in fully functioning EmONC facilities, but an additional 30% occurred in facilities missing one or two basic signal functions-most often assisted vaginal delivery and removal of retained products. Tackling these missing signal functions would extend births taking place in fully functioning facilities to over 50%. Subnational analyses based on estimated total pregnancies in each district revealed a pattern of inequity in service provision across the country. Upgrading facilities missing only one or two signal functions will allow Ghana to meet international standards for availability of EmONC services. Reducing maternal deaths will require high national priority given to addressing inequities in the distribution of EmONC services. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  17. Final Environmental Assessment Addressing 21st Explosive Ordinance Disposal Weapons of Mass Destruction Facilities Demolition and Expansion at Kirtland Air Force Base, New Mexico

    DTIC Science & Technology

    2011-07-01

    KIRTLAND AIR FORCE BASE, NEW MEXICO JULY 2011 Report Documentation Page Form ApprovedOMB No. 0704...Facilities Demolition and Expansion at Kirtland Air Force Base, New Mexico 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...EXPANSION KIRTLAND AIR FORCE BASE, NEW MEXICO Pursuant to the Council on Environmental Quality (CEQ) regulations for implementing procedural

  18. Validation of vision-based obstacle detection algorithms for low-altitude helicopter flight

    NASA Technical Reports Server (NTRS)

    Suorsa, Raymond; Sridhar, Banavar

    1991-01-01

    A validation facility being used at the NASA Ames Research Center is described which is aimed at testing vision based obstacle detection and range estimation algorithms suitable for low level helicopter flight. The facility is capable of processing hundreds of frames of calibrated multicamera 6 degree-of-freedom motion image sequencies, generating calibrated multicamera laboratory images using convenient window-based software, and viewing range estimation results from different algorithms along with truth data using powerful window-based visualization software.

  19. Potential advantages associated with implementing a risk-based inspection program by a nuclear facility

    NASA Astrophysics Data System (ADS)

    McNeill, Alexander, III; Balkey, Kenneth R.

    1995-05-01

    The current inservice inspection activities at a U.S. nuclear facility are based upon the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code, Section XI. The Code selects examination locations based upon a sampling criteria which includes component geometry, stress, and usage among other criteria. This can result in a significant number of required examinations. As a result of regulatory action each nuclear facility has conducted probabilistic risk assessments (PRA) or individual plant examinations (IPE), producing plant specific risk-based information. Several initiatives have been introduced to apply this new plant risk information. Among these initiatives is risk-based inservice inspection. A code case has been introduced for piping inspections based upon this new risk- based technology. This effort brought forward to the ASME Section XI Code committee, has been initiated and championed by the ASME Research Task Force on Risk-Based Inspection Guidelines -- LWR Nuclear Power Plant Application. Preliminary assessments associated with the code case have revealed that potential advantages exist in a risk-based inservice inspection program with regard to a number of exams, risk, personnel exposure, and cost.

  20. Operator Interface for the ALMA Observing System

    NASA Astrophysics Data System (ADS)

    Grosbøl, P.; Schilling, M.

    2009-09-01

    The Atacama Large Millimeter/submillimeter Array (ALMA) is a major new ground-based radio-astronomical facility being constructed in Chile in an international collaboration between Europe, Japan and North America in cooperation with the Republic of Chile. The facility will include 54 12m and 12 7m antennas at the Altiplano de Chajnantor and be operated from the Operations Support Facilities (OSF) near San Pedro. This paper describes design and baseline implementation of the Graphical User Interface (GUI) used by operators to monitor and control the observing facility. It is written in Java and provides a simple plug-in interface which allows different subsystems to add their own panels to the GUI. The design is based on a client/server concept and supports multiple operators to share or monitor operations.

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