Sample records for baseline change request

  1. Comparing spatially static and dynamic vibrotactile take-over requests in the driver seat.

    PubMed

    Petermeijer, S M; Cieler, S; de Winter, J C F

    2017-02-01

    Vibrotactile stimuli can be effective as warning signals, but their effectiveness as directional take-over requests in automated driving is yet unknown. This study aimed to investigate the correct response rate, reaction times, and eye and head orientation for static versus dynamic directional take-over requests presented via vibrating motors in the driver seat. In a driving simulator, eighteen participants performed three sessions: 1) a session involving no driving (Baseline), 2) driving a highly automated car without additional task (HAD), and 3) driving a highly automated car while performing a mentally demanding task (N-Back). Per session, participants received four directional static (in the left or right part of the seat) and four dynamic (moving from one side towards the opposite left or right of the seat) take-over requests via two 6×4 motor matrices embedded in the seat back and bottom. In the Baseline condition, participants reported whether the cue was left or right, and in the HAD and N-Back conditions participants had to change lanes to the left or to the right according to the directional cue. The correct response rate was operationalized as the accuracy of the self-reported direction (Baseline session) and the accuracy of the lane change direction (HAD & N-Back sessions). The results showed that the correct response rate ranged between 94% for static patterns in the Baseline session and 74% for dynamic patterns in the N-Back session, although these effects were not statistically significant. Steering wheel touch and steering input reaction times were approximately 200ms faster for static patterns than for dynamic ones. Eye tracking results revealed a correspondence between head/eye-gaze direction and lane change direction, and showed that head and eye-gaze movements where initiated faster for static vibrations than for dynamic ones. In conclusion, vibrotactile stimuli presented via the driver seat are effective as warnings, but their effectiveness as directional take-over requests may be limited. The present study may encourage further investigation into how to get drivers safely back into the loop. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Computational fluid dynamics (CFD) in the design of a water-jet-drive system

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto

    1994-01-01

    NASA/Marshall Space Flight Center (MSFC) has an ongoing effort to transfer to industry the technologies developed at MSFC for rocket propulsion systems. The Technology Utilization (TU) Office at MSFC promotes these efforts and accepts requests for assistance from industry. One such solicitation involves a request from North American Marine Jet, Inc. (NAMJ) for assistance in the design of a water-jet-drive system to fill a gap in NAMJ's product line. NAMJ provided MSFC with a baseline axial flow impeller design as well as the relevant working parameters (rpm, flow rate, etc.). This baseline design was analyzed using CFD, and significant deficiencies identified. Four additional analyses were performed involving MSFC changes to the geometric and operational parameters of the baseline case. Subsequently, the impeller was redesigned by NAMJ and analyzed by MSFC. This new configuration performs significantly better than the baseline design. Similar cooperative activities are planned for the design of the jet-drive inlet.

  3. Does children's screen time predict requests for advertised products? Cross-sectional and prospective analyses.

    PubMed

    Chamberlain, Lisa J; Wang, Yun; Robinson, Thomas N

    2006-04-01

    To examine children's screen media exposure and requests for advertised toys and food/drinks. Prospective cohort study. Twelve elementary schools in northern California. Eight hundred twenty-seven third grade children participated at baseline; 386 students in 6 schools were followed up for 20 months. None. Child self-reported requests for advertised toys and foods/drinks. At baseline, children's screen media time was significantly associated with concurrent requests for advertised toys (Spearman r = 0.15 [TV viewing] and r = 0.20 [total screen time]; both P<.001) and foods/drinks (Spearman r = 0.16 [TV viewing] and r = 0.18 [total screen time]; both P<.001). In prospective analysis, children's screen media time at baseline was significantly associated with their mean number of toy requests 7 to 20 months later (Spearman r = 0.21 [TV viewing] and r = 0.24 [total screen time]; both P<.001) and foods/drinks requests (Spearman r = 0.14 [TV viewing] and r = 0.16 [total screen time]; both P<.01). After adjusting for baseline requests and sociodemographic variables, the relationship between screen media exposure and future requests for advertised foods/drinks remained significant for total TV viewing and total screen media exposure. The relationship with future requests for toys remained significant for total screen media exposure. Screen media exposure is a prospective risk factor for children's requests for advertised products. Future experimental studies on children's health- and consumer-related outcomes are warranted.

  4. Descriptive Study Analyzing Discrepancies in a Software Development Project Change Request (CR) Assessment Process and Recommendations for Process Improvements

    NASA Technical Reports Server (NTRS)

    Cunningham, Kenneth J.

    2002-01-01

    The Change Request (CR) assessment process is essential in the display development cycle. The assessment process is performed to ensure that the changes stated in the description of the CR match the changes in the actual display requirements. If a discrepancy is found between the CR and the requirements, the CR must be returned to the originator for corrections. Data will be gathered from each of the developers to determine the type of discrepancies and the amount of time spent assessing each CR. This study will determine the most common types of discrepancies and the amount of time spent assessing those issues. The results of the study will provide a foundation for future improvements as well as a baseline for future studies.

  5. 75 FR 67768 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... submission of responses. Agency: Occupational Safety and Health Administration (OSHA). Type of Review: New...: The Department of Labor (DOL) hereby announces submission of the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR), ``Baseline Safety and Health Practices...

  6. 76 FR 29272 - Agency Information Collection Activities; Submission for OMB Emergency Review: Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... for OMB Emergency Review: Comment Request; Baseline Information for Green Jobs and Health Care Impact..., ``Baseline Information for Green Jobs and Health Care Impact Evaluation of ARRA-funded Grants,'' to the... is preparation for an evaluation of the Green Jobs and Health Care (GJHC) training grants. The ETA...

  7. Method for controlling powertrain pumps

    DOEpatents

    Sime, Karl Andrew; Spohn, Brian L; Demirovic, Besim; Martini, Ryan D; Miller, Jean Marie

    2013-10-22

    A method of controlling a pump supplying a fluid to a transmission includes sensing a requested power and an excess power for a powertrain. The requested power substantially meets the needs of the powertrain, while the excess power is not part of the requested power. The method includes sensing a triggering condition in response to the ability to convert the excess power into heat in the transmission, and determining that an operating temperature of the transmission is below a maximum. The method also includes determining a calibrated baseline and a dissipation command for the pump. The calibrated baseline command is configured to supply the fluid based upon the requested power, and the dissipation command is configured to supply additional fluid and consume the excess power with the pump. The method operates the pump at a combined command, which is equal to the calibrated baseline command plus the dissipation command.

  8. Keeping Tabs on the Unique Jet in M87 During Cycle 19

    NASA Astrophysics Data System (ADS)

    Cheung, C. Teddy

    2017-09-01

    We request two observations of M87 at 5 ks each. The first should be in Dec 2017 and the second in 2018 Mar. There are three reasons for this modest request: (1) If our companion M87 ToO proposal is triggered, we need to know the X-ray intensity of each component in the jet before the onset of TeV flaring. (2) Ascertain if the intensities of the known X-ray variable nucleus and knot HST-1, as well as knot D (known to be optically variable with superluminal sub-structures) have increased substantially since our most recent observation; if we were to find a substantial change, a DDT request would be instigated. (3) Extend the time baseline for evaluation of long term intensity decay of knots as expected for synchrotron losses of high energy electrons responsible for X-ray emission.

  9. A communication-based intervention for nonverbal children with autism: what changes? Who benefits?

    PubMed

    Gordon, Kate; Pasco, Greg; McElduff, Fiona; Wade, Angie; Howlin, Pat; Charman, Tony

    2011-08-01

    This article examines the form and function of spontaneous communication and outcome predictors in nonverbal children with autism following classroom-based intervention (Picture Exchange Communication System [PECS] training). 84 children from 15 schools participated in a randomized controlled trial (RCT) of PECS (P. Howlin, R. K. Gordon, G. Pasco, A. Wade, & T. Charman, 2007). They were aged 4-10 years (73 boys). Primary outcome measure was naturalistic observation of communication in the classroom. Multilevel Poisson regression was used to test for intervention effects and outcome predictors. Spontaneous communication using picture cards, speech, or both increased significantly following training (rate ratio [RR] =1.90, 95% CI [1.46, 2.48], p < .001; RR = 1.77, 95% CI [1.35, 2.32], p < .001; RR = 3.74, 95% CI [2.19, 6.37], p < .001, respectively). Spontaneous communication to request objects significantly increased (RR = 2.17, 95% CI [1.75, 2.68], p < .001), but spontaneous requesting for social purposes did not (RR = 1.34, 95% CI [0.83, 2.18], p = .237). Only the effect on spontaneous speech persisted by follow-up (9 months later). Less severe baseline autism symptomatology (lower Autism Diagnosis Observation Schedule [ADOS] score; C. Lord et al., 2000) was associated with greater increase in spontaneous speech (RR = 0.90, 95% CI [0.83, 0.98], p = .011) and less severe baseline expressive language impairment (lower ADOS item A1 score), with larger increases in spontaneous use of speech and pictures together (RR = 0.62, 95% CI [0.44, 0.88], p = .008). Overall, PECS appeared to enhance children's spontaneous communication for instrumental requesting using pictures, speech, or a combination of both. Some effects of training were moderated by baseline factors. For example, PECS appears to have increased spontaneous speech in children who could talk a little at baseline.

  10. 76 FR 7827 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    .... Baseline data for the B&B:08 cohort were collected as part of the National Postsecondary Student Aid Study... administrative data sources, including the Central Processing System, the National Student Loan Data System, and the National Student Clearinghouse. This request also requests a waiver of the 60-day Federal Register...

  11. Structured education to improve primary-care management of headache: how long do the benefits last? A follow-up observational study.

    PubMed

    Braschinsky, M; Haldre, S; Kals, M; Arge, M; Saar, B; Niibek, M; Katsarava, Z; Steiner, T J

    2018-03-01

    Our earlier study showed that structured education of general practitioners (GPs) improved their practice in headache management. Here the duration of this effect was assessed. In a follow-up observational study in southern Estonia, subjects were the same six GPs as previously, managing patients presenting with headache as the main complaint. Data reflecting their practice were collected prospectively during a 1-year period commencing 2 years after the educational intervention. The primary outcome measure was referral rate (RR) to neurological services. Comparisons were made with baseline and post-intervention data from the earlier study. In 366 patients consulting during the follow-up period, the RR was 19.9%, lower than at baseline (39.5%; P < 0.0001) or post-intervention (34.7%; P < 0.0001). The RR was diagnosis-dependent: the biggest decline was for migraine. Use of headache diagnostic terms showed changes generally favouring specific terminology. In particular, the proportion of patients given migraine diagnoses greatly increased whilst use of the inappropriate M79.1 (Pericranial) myalgia almost disappeared. Requests for investigations, which had fallen from 26% (of patients seen) at baseline to 4% post-intervention, resurged to 23% (mostly laboratory investigations; requests for X-rays continued to dwindle). Initiation of treatment by the GPs remained at the post-intervention level of just over 80% (up from baseline 58%). Improvements in GPs' practice after a structured educational programme mostly last for ≥3 years, some showing further betterment. A few measures suggest the beginnings of a decline towards baseline levels. This policy-informing evidence for continuing medical education indicates that the educational programme needs repeating every 2-3 years. © 2017 EAN.

  12. 78 FR 11869 - Proposed Information Collection Request; Comment Request; Registration of Fuels and Fuel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... biodiesel, water/diesel emulsions, several atypical additives, and renewable gasoline and diesel fuels. Tier... health effects. Tier 2 data have been submitted for baseline diesel, biodiesel, and water/diesel...

  13. 78 FR 41059 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... for biodiesel, water/diesel emulsions, several atypical additives, and renewable gasoline and diesel... adverse health effects. Tier 2 data have been submitted for baseline diesel, biodiesel, and water/diesel...

  14. 77 FR 71431 - New Agency Information Collection Activity Under OMB Review: Highway Baseline Assessment for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... Collection Activity Under OMB Review: Highway Baseline Assessment for Security Enhancement (BASE) Program... Assessment for Security Enhancement (BASE) Program. Type of Request: New collection. OMB Control Number: Not yet assigned. Form(s): Highway Baseline Assessment for Security Enhancement (BASE). Affected Public...

  15. Runway Independent Aircraft Extremely Short Takeoff and Landing Regional Airliner: The Model 110

    NASA Technical Reports Server (NTRS)

    Hall, David W.

    2003-01-01

    Airports throughout the United States are plagued with growing congestion. With the increase in air traffic predicted in the next few years, congestion will worsen. The accepted solution of building larger airplanes to carry more travelers is no longer a viable option, as airports are unable to accommodate larger aircraft without expensive infrastructure changes. Past NASA research has pointed to the need for a new approach, which can economically and safely utilize smaller airports. To study this option further, NASA requested the California Polytechnic State University at San Luis Obispo (Cal Poly/SLO) to design a baseline aircraft to be used for system studies. The requirements put forth by NASA are summarized. The design team was requested to create a demonstrator vehicle, which could be built without requiring enabling technology development. To this end, NASA requested that the tested and proven high-lift system of the Boeing C-17 Globemaster III be combined with the fuselage of the BAe-146. NASA also requested that Cal Poly determine the availability and usability of underutilized airports starting with California, then expanding if time and funds permitted to the U.S.

  16. 75 FR 9418 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... OMB Review; Comment Request Title: Evaluation of Adolescent Pregnancy Prevention Approaches-- Baseline... part of the Evaluation of Adolescent Pregnancy Prevention Approaches (PPA). PPA is being undertaken to expand available evidence on effective ways to reduce teen pregnancy. The evaluation will document and...

  17. 77 FR 506 - Agency Information Collection Request. 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    .... Proposed Project: Teen Pregnancy Prevention Replication Evaluation Study: Baseline Data Collection--OMB No... for Children and Families (ACF) on adolescent pregnancy prevention evaluation activities. OAH will jointly oversee with ASPE the Teen Pregnancy Prevention Replication Evaluation Study (TPP Replication...

  18. Product retrieval time in small tobacco retail outlets before and after the Australian plain packaging policy: real-world study.

    PubMed

    Wakefield, Melanie; Bayly, Megan; Scollo, Michelle

    2014-01-01

    We aimed to assess change in cigarette pack retrieval time in small retail outlets following the introduction of plain packaging in Australia in 1 December 2012. A sample of 303 milk bars, convenience stores, petrol stations and newsagents was selected in four capital cities, stratified by area socioeconomic status. In June and September (baseline months), the first 2 weeks of December 2012, and February 2013, stores were visited by trained fieldworkers who requested a cigarette pack of a pre-determined brand, variant and pack size, unobtrusively recording the time from the end of the request to when the pack was scanned or placed on the counter. In multivariate analysis, December retrieval time (12.43 s) did not differ from June (10.91 s; p=0.410) or February (10.37 s; p=0.382), but was slower than September (9.84 s; p=0.024). In December, retrieval time declined as days after plain packaging implementation increased (β=-0.21, p=0.011), returning to the baseline range by the second week of implementation. This pattern was not observed in baseline months or in February. Sensitivity analyses showed that results were robust to the variability in purchasing circumstances in tobacco retail outlets. Retailers quickly gained experience with the new plain packaging legislation, evidenced by retrieval time having returned to the baseline range by the second week of implementation and remaining so several months later. The long retrieval times predicted by tobacco industry-funded retailer groups and the consequent costs they predicted would fall upon small retailers from plain packaging are unlikely to eventuate.

  19. 76 FR 14399 - Agency Information Collection Request; 60-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    .... Proposed Project: Evaluation of Adolescent Pregnancy Prevention Approaches and the Impact Evaluation of the Teen Pregnancy Prevention Program Grantees: Baseline Data Collection--OMB No. OS-0990--NEW-- Office of... overseeing and coordinating adolescent pregnancy prevention evaluation efforts as part of the Teen Pregnancy...

  20. 77 FR 57074 - Proposed Information Collection; Comment Request; Social Capital Survey of Northeast Groundfish...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... Collection; Comment Request; Social Capital Survey of Northeast Groundfish Fishery Permit Holders AGENCY... action over time. The value of these relationships is commonly referred to in social and economic literature as social capital. A baseline of existing social capital in the groundfish fishery in the...

  1. A rapid response air quality analysis system for use in projects having stringent quality assurance requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bowman, A.W.

    1990-04-01

    This paper describes an approach to solve air quality problems which frequently occur during iterations of the baseline change process. From a schedule standpoint, it is desirable to perform this evaluation in as short a time as possible while budgetary pressures limit the size of the staff available to do the work. Without a method in place to deal with baseline change proposal requests the environment analysts may not be able to produce the analysis results in the time frame expected. Using a concept called the Rapid Response Air Quality Analysis System (RAAS), the problems of timing and cost becomemore » tractable. The system could be adapted to assess other atmospheric pathway impacts, e.g., acoustics or visibility. The air quality analysis system used to perform the EA analysis (EA) for the Salt Repository Project (part of the Civilian Radioactive Waste Management Program), and later to evaluate the consequences of proposed baseline changes, consists of three components: Emission source data files; Emission rates contained in spreadsheets; Impact assessment model codes. The spreadsheets contain user-written codes (macros) that calculate emission rates from (1) emission source data (e.g., numbers and locations of sources, detailed operating schedules, and source specifications including horsepower, load factor, and duty cycle); (2) emission factors such as those published by the U.S. Environmental Protection Agency, and (3) control efficiencies.« less

  2. 38 CFR 20.1304 - Rule 1304. Request for change in representation, request for personal hearing, or submission of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... change in representation, request for personal hearing, or submission of additional evidence following... Miscellaneous § 20.1304 Rule 1304. Request for change in representation, request for personal hearing, or...) Request for a change in representation, request for a personal hearing, or submission of additional...

  3. 76 FR 71036 - Agency Information Collection Request. 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... performance of the agency's functions; (2) the accuracy of the estimated burden; (3) ways to enhance the... three waves of in- person data collection collected from incarcerated and released fathers and their... months post-baseline in five sites. A fourth wave of data collection at approximately 34 months, will be...

  4. 76 FR 51980 - Agency Information Collection Request. 60-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    ... collection for the proper performance of the agency's functions; (2) the accuracy of the estimated burden; (3... for the evaluation will come from three waves of in- person data collection collected from... follow-up surveys at approximately 9 and 18 months post-baseline in five sites. A fourth wave of data...

  5. 77 FR 37047 - Agency Information Collection Request; 60-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    ... collection for the proper performance of the agency's functions; (2) the accuracy of the estimated burden; (3... ordering physicians. The anticipated bi-annual data collection effort will be conducted in two waves--Wave I in November of 2012 will establish the baseline and Wave II in 2014 will measure progress...

  6. Long-term organ damage accrual and safety in patients with SLE treated with belimumab plus standard of care.

    PubMed

    Bruce, I N; Urowitz, M; van Vollenhoven, R; Aranow, C; Fettiplace, J; Oldham, M; Wilson, B; Molta, C; Roth, D; Gordon, D

    2016-06-01

    To examine long-term organ damage and safety following treatment with belimumab plus standard of care (SoC) in patients with systemic lupus erythematosus (SLE). Pooled data were examined from two ongoing open-label studies that enrolled patients who completed BLISS-52 or BLISS-76. Patients received belimumab every four weeks plus SoC. SLICC Damage Index (SDI) values were assessed every 48 weeks (study years) following belimumab initiation (baseline). The primary endpoint was change in SDI from baseline at study years 5-6. Incidences of adverse events (AEs) were reported for the entire study period. The modified intent-to-treat (MITT) population comprised 998 patients. At baseline, 940 (94.2%) were female, mean (SD) age was 38.7 (11.49) years, and disease duration was 6.7 (6.24) years. The mean (SD) SELENA-SLEDAI and SDI scores were 8.2 (4.18) and 0.7 (1.19), respectively; 411 (41.2%) patients had organ damage (SDI = 1: 235 (23.5%); SDI ≥ 2: 176 (17.6%)) prior to belimumab. A total of 427 (42.8%) patients withdrew overall; the most common reasons were patient request (16.8%) and AEs (8.5%).The mean (SD) change in SDI was +0.2 (0.48) at study years 5-6 (n = 403); 343 (85.1%) patients had no change from baseline in SDI score (SDI +1: 46 (11.4%), SDI +2: 13 (3.2%), SDI +3: 1 (0.2%)). Of patients without organ damage at baseline, 211/241 (87.6%) had no change in SDI and the mean change (SD) in SDI was +0.2 (0.44). Of patients with organ damage at baseline, 132/162 (81.5%) had no change in SDI and the mean (SD) change in SDI was +0.2 (0.53). The probability of not having a worsening in SDI score was 0.88 (95% CI: 0.85, 0.91) and 0.75 (0.67, 0.81) in those without and with baseline damage, respectively (post hoc analysis).Drug-related AEs were reported for 433 (43.4%) patients; infections/infestations (282, 28.3%) and gastrointestinal disorders (139, 13.9%) were the most common. Patients with SLE treated with long-term belimumab plus SoC had a low incidence of organ damage accrual and no unexpected AEs. High-risk patients with pre-existing organ damage also had low accrual, suggesting a favorable effect on future damage development. © The Author(s) 2016.

  7. 40 CFR 74.10 - Roles-EPA and permitting authority.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... opt-in provisions of the Acid Rain Program: (1) Calculating the baseline or alternative baseline and... withdrawal conditions prior to withdrawal from the Acid Rain Program as provided under § 74.18; and (5) Approving and disapproving the request to withdraw from the Acid Rain Program. (b) Permitting authority...

  8. 40 CFR 74.10 - Roles-EPA and permitting authority.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... opt-in provisions of the Acid Rain Program: (1) Calculating the baseline or alternative baseline and... withdrawal conditions prior to withdrawal from the Acid Rain Program as provided under § 74.18; and (5) Approving and disapproving the request to withdraw from the Acid Rain Program. (b) Permitting authority...

  9. 40 CFR 74.10 - Roles-EPA and permitting authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... opt-in provisions of the Acid Rain Program: (1) Calculating the baseline or alternative baseline and... withdrawal conditions prior to withdrawal from the Acid Rain Program as provided under § 74.18; and (5) Approving and disapproving the request to withdraw from the Acid Rain Program. (b) Permitting authority...

  10. 40 CFR 74.10 - Roles-EPA and permitting authority.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... opt-in provisions of the Acid Rain Program: (1) Calculating the baseline or alternative baseline and... withdrawal conditions prior to withdrawal from the Acid Rain Program as provided under § 74.18; and (5) Approving and disapproving the request to withdraw from the Acid Rain Program. (b) Permitting authority...

  11. 77 FR 50140 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... disorders. Administered at baseline only. d. Questions on trauma events to document adult, childhood, and recent trauma. Lifetime questions administered at baseline only and recent at six month. e. Questions on trauma symptoms using the Post-Traumatic Disorder Checklist--Civilian (PCL-C) to document trauma...

  12. 77 FR 64528 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... include: a. Questions about housing stability, one about recentcy of homelessness and the number of days homeless in the past 6 months. Administered at baseline only. b. Questions about lifetime incidence of.... Administered at baseline only. d. Questions on trauma events to document adult, childhood, and recent trauma...

  13. 77 FR 30306 - Notice of Proposed Information Collection: Comment Request; Request for Acceptance of Changes in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... Information Collection: Comment Request; Request for Acceptance of Changes in Approved Drawings and... also lists the following information: Title of Proposal: Changes in Approved Drawings and... proposed use: Builders who request changes to HUD's accepted drawings and specifications for proposed...

  14. Acquisition and Generalization of the Picture Exchange Communication System Behaviors across Settings, Persons, and Stimulus Classes with Three Students with Autism

    ERIC Educational Resources Information Center

    Dogoe, Maud S.; Banda, Devender R.; Lock, Robin H.

    2010-01-01

    This study examined the acquisition and generalization of requesting behaviors learned through PECS with three children with autism. A single-subject multiple baseline across participants design was used to determine the effects of PECS. Results indicated that all three participants acquired PECS skills for requesting and generalized the skills…

  15. Teaching young people who are blind and have autism to make requests using a variation on the picture exchange communication system with tactile symbols: a preliminary investigation.

    PubMed

    Lund, Shelley K; Troha, Jeanette M

    2008-04-01

    This study used a single-subject multiple baseline across participants design to evaluate the effectiveness of a modified picture exchange communication system (PECS) teaching protocol with tactile symbols. Three students (two male, one female) aged 12-17 years who had autism and were blind participated in the study. The instructional program involved three phases. First, each participant learned to exchange a tactile symbol with his/her communication partner to request a preferred item/activity. Second, the distance between the communication partner and the participant was increased. Third, the participants were required to discriminate between two dissimilar tactile symbols. One out of three participants completed all phases of the instructional program. Although the other two participants did not complete the program, they demonstrated improvement from baseline responding rates. This study provided preliminary results that using tactile symbols with strategies from PECS may be an effective method to teach requesting to youth who are blind and have autism.

  16. 76 FR 60084 - Extension Request for Collection of Baseline Information for Green Jobs and Health Care Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Baseline Information for Green Jobs and Health Care Impact Evaluation of ARRA-Funded Grants AGENCY... the Green Jobs and Health Care American Recovery and Reinvestment Act of 2009 (ARRA or Recovery Act... supports an evaluation of the impacts of the Green Jobs and Health Care (GJHC) training grants. This...

  17. Pester power and its consequences: do European children's food purchasing requests relate to diet and weight outcomes?

    PubMed

    Huang, Christina Y; Reisch, Lucia A; Gwozdz, Wencke; Molnár, Dénes; Konstabel, Kenn; Michels, Nathalie; Tornaritis, Michalis; Eiben, Gabriele; Siani, Alfonso; Fernández-Alvira, Juan M; Ahrens, Wolfgang; Pigeot, Iris; Lissner, Lauren

    2016-09-01

    Children may influence household spending through 'pester power'. The present study examined pestering through parent-child food shopping behaviours in relation to children's diet and weight status. Cross-sectional and prospective analyses drawn from the IDEFICS study, a cohort study of parents and their children. Children's height and weight were measured and their recent diets were reported by parental proxy based on the Children's Eating Habits Questionnaire-FFQ at baseline and 2-year follow-up. Parents also completed questionnaires at both time points about pestering, including whether the child goes grocery shopping with them, asks for items seen on television and is bought requested food items. Participants were recruited from eight European countries for the IDEFICS study (non-nationally representative sample). Study participants were children aged 2-9 years at enrolment and their parents. A total of 13 217 parent-child dyads were included at baseline. Two years later, 7820 of the children were re-examined. Most parents (63 %) at baseline reported 'sometimes' acquiescing to their children's requests to purchase specific foods. Pestering was modestly associated with weight and diet. At baseline, children whose parents 'often' complied consumed more high-sugar and high-fat foods. Children who 'often' asked for items seen on television were likely to become overweight after 2 years (OR=1·31), whereas 'never' asking protected against overweight (OR=0·72). Pestering was modestly related to diet and weight in cross-sectional, but not longitudinal analyses. Asking for items seen on television had the most robust relationships across child outcomes and over time.

  18. Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma.

    PubMed

    Simeone, Ester; Gentilcore, Giusy; Giannarelli, Diana; Grimaldi, Antonio M; Caracò, Corrado; Curvietto, Marcello; Esposito, Assunta; Paone, Miriam; Palla, Marco; Cavalcanti, Ernesta; Sandomenico, Fabio; Petrillo, Antonella; Botti, Gerardo; Fulciniti, Franco; Palmieri, Giuseppe; Queirolo, Paola; Marchetti, Paolo; Ferraresi, Virginia; Rinaldi, Gaetana; Pistillo, Maria Pia; Ciliberto, Gennaro; Mozzillo, Nicola; Ascierto, Paolo A

    2014-07-01

    Ipilimumab can induce durable disease control and long-term survival in patients with metastatic melanoma. Identification of a biomarker that correlates with clinical benefit and potentially provides an early marker of response is an active area of research. Ipilimumab was available upon physician request for patients aged ≥16 years with stage III (unresectable) or IV cutaneous, ocular or mucosal melanoma, who had failed or did not tolerate previous treatments and had no other therapeutic option available. Patients received ipilimumab 3 mg/kg every 3 weeks for four doses. Tumour assessments were conducted at baseline, Week 12 and Week 24 using immune-related response criteria. Patients were monitored continuously for adverse events (AEs), including immune-related AEs. Candidate immunological markers were evaluated in peripheral blood and sera samples collected at baseline and Weeks 4, 7, 10 and 12. Among 95 patients treated with ipilimumab 3 mg/kg, the immune-related disease control rate at Week 24 was 38 %. With a median follow-up of 24 months, median overall survival was 9.6 months. Both disease control and survival were significantly associated with decreasing levels of lactate dehydrogenase, C-reactive protein and FoxP3/regulatory T cells, and increasing absolute lymphocyte count, between baseline and the end of dosing (Week 12). Ipilimumab is a feasible treatment option for heavily pretreated patients with metastatic melanoma. Changes in some immunological markers between baseline and the fourth ipilimumab infusion appear to be associated with disease control and survival, but verification in prospective clinical trials is required.

  19. Impact of the picture exchange communication system: effects on communication and collateral effects on maladaptive behaviors.

    PubMed

    Ganz, Jennifer B; Parker, Richard; Benson, Joanne

    2009-12-01

    Many children with autism require intensive instruction in the use of augmentative or alternative communication systems, such as the Picture Exchange Communication System (PECS). This study investigated the use of PECS with three young boys with autism to determine the impact of PECS training on use of pictures for requesting, use of intelligible words, and maladaptive behaviors. A multiple baseline-probe design with a staggered start was implemented. Results indicated that all of the participants quickly learned to make requests using pictures and that two used intelligible speech following PECS instruction; maladaptive behaviors were variable throughout baseline and intervention phases. Although all of the participants improved in at least one dependent variable, there remain questions regarding who is best suited for PECS and similar interventions.

  20. 78 FR 4124 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ...: National Oceanic and Atmospheric Administration (NOAA). Title: Social Capital Survey of Northeast... relationships is commonly referred to in social and economic literature. A baseline of existing social capital...

  1. Impact of introducing near patient testing for standard investigations in general practice.

    PubMed Central

    Rink, E; Hilton, S; Szczepura, A; Fletcher, J; Sibbald, B; Davies, C; Freeling, P; Stilwell, J

    1993-01-01

    OBJECTIVE--To assess the clinical and economic impact of surgery based near patient testing in general practice for six commonly used biochemical and bacteriological tests. DESIGN--After four months' monitoring, equipment for two bacteriological and four biochemical tests was introduced without cost into 12 practices using a crossover design. Structured request forms were used to monitor laboratory investigations. SETTING--12 general practices in west midlands and south west Thames with list sizes above 9000. MAIN OUTCOME MEASURES--Investigation rates per 1000 consultations. Changes from baseline rates. Reasons for requesting investigations and provisional diagnoses. Cost per test and sensitivity of costs to rate of use. RESULTS--Investigation rates for the six tests rose by 16.5% (from 78.6/1000 consultations to 91.6/1000) when equipment was available in the surgery and reverted to baseline rates when it was withdrawn. The average weekly number of tests when equipment was available ranged from 0.5 to 10.5 (mean 9.0). Cholesterol tests were used as an addition to laboratory testing, usually for screening. Midstream urine analysis was often done in the surgery instead of in the laboratory, although 30% of samples were tested by both methods. Doctors' reasons for investigation and conditions tested were largely unaffected by availability of surgery tests. Costs for surgery tests were higher for all tests except midstream urine. CONCLUSIONS--Availability of surgery based testing increased the number of tests performed. It was cost effective only for midstream urine analysis. PMID:8219952

  2. 78 FR 8152 - Proposed Collection; Comment Request: Women's Health Initiative Observational Study

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... of Management and Budget (OMB) for review and approval. Proposed Collection: Title: The Women's... women and relating subsequent disease development to baseline assessments of historical, physical...

  3. Using pathology-specific laboratory profiles in Clinical Pathology to reduce inappropriate test requesting: two completed audit cycles

    PubMed Central

    2012-01-01

    Background Systematic reviews have shown that, although well prepared, the Consensus Guidelines have failed to change clinical practice. In the healthcare district of Castelnovo né Monti (Reggio Emilia, Italy), it became necessary for the GPs and Clinical Pathologists to work together to jointly define laboratory profiles. Methods Observational study with two cycles of retrospective audit on test request forms, in a primary care setting. Objectives of the study were to develop pathology-specific laboratory profiles and to increase the number of provisional diagnoses on laboratory test request forms. A Multiprofessional Multidisciplinary Inter-hospital Work Team developed pathology-specific laboratory profiles for more effective test requesting. After 8 training sessions that used a combined strategy with multifaceted interventions, the 23 General Practitioners (GPs) in the trial district (Castelnovo nè Monti) tested the profiles; the 21 GPs in the Puianello district were the control group; all GPs in both districts participated in the trial. All laboratory tests for both healthcare districts are performed at the Laboratory located in the trial district. A baseline and a 1-year audit were performed in both districts on the GPs’ request forms. Results Seven pathology-specific laboratory profiles for outpatients were developed. In the year after the first audit cycle: 1) the number of tests requested in the trial district was distinctly lower than that in the previous year, with a decrease of about 5% (p < 0.001); 2) the provisional diagnosis on the request forms was 52.8% in the trial district and 42% in the control district (P < 0.001); 3) the decrease of the number of tests on each request form was much more marked in the trial district (8.73 vs. 10.77; p < 0.001). Conclusions The first audit cycle showed a significant decrease in the number of tests ordered only in the trial district. The combined strategy used in this study improved the prescriptive compliance of most of the GPs involved. The presence of the clinical pathologist is seen as an added value. PMID:22759353

  4. Using pathology-specific laboratory profiles in clinical pathology to reduce inappropriate test requesting: two completed audit cycles.

    PubMed

    Baricchi, Roberto; Zini, Michele; Nibali, Maria Grazia; Vezzosi, Walter; Insegnante, Vincenzo; Manfuso, Clotilde; Polese, Alessandra; Costoli, Valmer; Spelti, Antonio; Formisano, Debora; Orlandini, Danilo; Nicolini, Fausto; Poli, Antonio

    2012-07-03

    Systematic reviews have shown that, although well prepared, the Consensus Guidelines have failed to change clinical practice. In the healthcare district of Castelnovo né Monti (Reggio Emilia, Italy), it became necessary for the GPs and Clinical Pathologists to work together to jointly define laboratory profiles. Observational study with two cycles of retrospective audit on test request forms, in a primary care setting. Objectives of the study were to develop pathology-specific laboratory profiles and to increase the number of provisional diagnoses on laboratory test request forms. A Multiprofessional Multidisciplinary Inter-hospital Work Team developed pathology-specific laboratory profiles for more effective test requesting. After 8 training sessions that used a combined strategy with multifaceted interventions, the 23 General Practitioners (GPs) in the trial district (Castelnovo nè Monti) tested the profiles; the 21 GPs in the Puianello district were the control group; all GPs in both districts participated in the trial. All laboratory tests for both healthcare districts are performed at the Laboratory located in the trial district. A baseline and a 1-year audit were performed in both districts on the GPs' request forms. Seven pathology-specific laboratory profiles for outpatients were developed. In the year after the first audit cycle: 1) the number of tests requested in the trial district was distinctly lower than that in the previous year, with a decrease of about 5% (p < 0.001); 2) the provisional diagnosis on the request forms was 52.8% in the trial district and 42% in the control district (P < 0.001); 3) the decrease of the number of tests on each request form was much more marked in the trial district (8.73 vs. 10.77; p < 0.001). The first audit cycle showed a significant decrease in the number of tests ordered only in the trial district. The combined strategy used in this study improved the prescriptive compliance of most of the GPs involved. The presence of the clinical pathologist is seen as an added value.

  5. A Preliminary Analysis of Teaching Improvisation with the Picture Exchange Communication System to Children with Autism

    PubMed Central

    Marckel, Julie M; Neef, Nancy A; Ferreri, Summer J

    2006-01-01

    Two young boys with autism who used the picture exchange communication system were taught to solve problems (improvise) by using descriptors (functions, colors, and shapes) to request desired items for which specific pictures were unavailable. The results of a multiple baseline across descriptors showed that training increased the number of improvised requests, and that these skills generalized to novel items, and across settings and listeners in the natural environment. PMID:16602390

  6. A preliminary analysis of teaching improvisation with the picture exchange communication system to children with autism.

    PubMed

    Marckel, Julie M; Neef, Nancy A; Ferreri, Summer J

    2006-01-01

    Two young boys with autism who used the picture exchange communication system were taught to solve problems (improvise) by using descriptors (functions, colors, and shapes) to request desired items for which specific pictures were unavailable. The results of a multiple baseline across descriptors showed that training increased the number of improvised requests, and that these skills generalized to novel items, and across settings and listeners in the natural environment.

  7. 76 FR 32997 - Submission for Review: RI 20-120, Request for Change to Unreduced Annuity

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... Annuity AGENCY: U.S. Office of Personnel Management. ACTION: 60-day notice and request for comments..., Request for Change to Unreduced Annuity. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104... Management. Title: Request for Change to Unreduced Annuity. OMB Number: 3206-0245. Frequency: On occasion...

  8. 76 FR 18810 - Submission for Review: Request To Change Federal Employees Health Benefits (FEHB) Enrollment for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ...) 3206-0202, Request to Change Federal Employees Health Benefits (FEHB) Enrollment for Spouse Equity... to Change Federal Employees Health Benefits (FEHB) Enrollment for Spouse Equity/Temporary... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Request To Change Federal Employees Health...

  9. 22 CFR 505.8 - Agency review of requests for changes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Agency review of requests for changes. 505.8... review of requests for changes. (a) In reviewing a record in response to a request to amend or correct a... record in the review. (b) If we agree with you to amend your records, we will: (1) Advise you in writing...

  10. Combined effect of new complete dentures and simple dietary advice on nutritional status in edentulous patients: study protocol for a randomized controlled trial.

    PubMed

    Komagamine, Yuriko; Kanazawa, Manabu; Iwaki, Maiko; Jo, Ayami; Suzuki, Hiroyuki; Amagai, Noriko; Minakuchi, Shunsuke

    2016-11-09

    Individuals who are edentulous have a lower intake of fruit, vegetables, fiber, and protein compared with their dentate counterparts because tooth loss is accompanied by a decrease in ability to chew. Whether or not a combination of prosthetic rehabilitation and simple dietary advice produces improvement in dietary intake among edentulous persons is unclear. We aim to investigate the effect of a simultaneous combination of simple dietary advice delivered by dentists and provision of new complete dentures on dietary intake in edentulous individuals who request new dentures. Through a double-blinded, parallel, randomized controlled trial in which 70 edentate persons who request new complete dentures will be enrolled, eligible study participants will be randomly allocated to either a dietary intervention group receiving dietary advice or to a control group receiving only advice on the care and maintenance of dentures. Outcome measures include daily intake of nutrients and food items, assessed using a brief self-administered diet history questionnaire; antioxidant capacity, determined using blood and urine samples; nutritional status, assessed with the Mini-Nutritional Assessment-Short Form; oral health-related quality of life, assessed with the Japanese version of the Oral Health Impact Profile-EDENT and the Geriatric Oral Health Assessment Index; subjective chewing ability; masticatory performance, assessed using a color-changeable chewing gum and a gummy jelly; patient self-assessment of dentures; mild cognitive impairment, assessed with the Japanese version of the Montreal Cognitive Assessment; and functional capacity, assessed with the Japan Science and Technology Agency Index of Competence. Outcome measures, except for antioxidant capacity, are to be implemented at three time points: at baseline and at 3 and 6 months following intervention. Antioxidant capacity data are to be collected twice: at baseline and at 3 months following intervention. Differences between the groups at 3 and 6 months and within-group changes are to be compared using the paired t test. Simple dietary advice that can be implemented by a dentist would be more practical in clinical practice than tailored dietary counseling. The results of this study will provide beneficial information on dietary intake changes for both edentulous individuals requesting new complete dentures and dentists. University Hospital Medical Information Network Center Unique Trial Number: UMIN000017879 . Registered on 12 June 2015.

  11. 75 FR 7634 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... public that the Postal Service has filed a request to add International Business Reply Service... entered into two additional International Business Reply Service (IBRS) Contracts.\\1\\ Additionally, the... to Establish Successor Instruments as Baseline International Business Reply Service Competitive...

  12. Golden Gate National Recreation Area : acoustical monitoring 2007/2008

    DOT National Transportation Integrated Search

    2011-03-01

    In 2007, the Natural Sounds Program (NPS) received a technical assistance request to collect baseline acoustical data at Golden Gate National Recreation Area (GGNRA). During the summer (June September 2007) and winter (January February 2008),...

  13. Collecting Unsolicited User-Generated Change Requests

    DTIC Science & Technology

    2015-12-01

    change requests, although the core principles of the steps apply equally to non- software change requests ( Champagne and April, 2014:pp 6-9). The...Capabilities Integration and Development System (JCIDS). JCIDS Manual. Washington: CJCS, 12 February 2015. Champagne , Roger and Alain April. “Software

  14. Establishing generative yes/no responses in developmentally disabled children.

    PubMed Central

    Neef, N A; Walters, J; Egel, A L

    1984-01-01

    We evaluated the effects of two procedures for teaching four developmentally disabled children to respond yes/no appropriately. During baseline, tutoring was conducted in which five known items were individually presented with the question, "Is this a ----?", followed either by access to requested items or by remedial prompting contingent on responding. When tutoring did not improve performance, instruction was embedded in the regular classroom activities. In this condition, items requested by students were either presented or withheld on the basis of their response to the question, "Do you want ----?". Increases in correct responding were confirmed by a multiple-baseline design across all four students and were maintained with the introduction of new items. However, generalization to "Is this a ----?" questions did not occur in the tutoring setting until specifically programmed. Subsequently, students also demonstrated appropriate yes/no responding to questions involving actions, possession, and spatial relations. PMID:6526766

  15. Constellation Program (CxP) Crew Exploration Vehicle (CEV) Project Integrated Landing System

    NASA Technical Reports Server (NTRS)

    Baker, John D.; Yuchnovicz, Daniel E.; Eisenman, David J.; Peer, Scott G.; Fasanella, Edward L.; Lawrence, Charles

    2009-01-01

    Crew Exploration Vehicle (CEV) Chief Engineer requested a risk comparison of the Integrated Landing System design developed by NASA and the design developed by Contractor- referred to as the LM 604 baseline. Based on the results of this risk comparison, the CEV Chief engineer requested that the NESC evaluate identified risks and develop strategies for their reduction or mitigation. The assessment progressed in two phases. A brief Phase I analysis was performed by the Water versus Land-Landing Team to compare the CEV Integrated Landing System proposed by the Contractor against the NASA TS-LRS001 baseline with respect to risk. A phase II effort examined the areas of critical importance to the overall landing risk, evaluating risk to the crew and to the CEV Crew Module (CM) during a nominal land-landing. The findings of the assessment are contained in this report.

  16. A multifaceted strategy for implementation of the Ottawa ankle rules in two emergency departments

    PubMed Central

    Clark, Robyn; Shakib, Sepehr; Hughes, Geoffrey

    2009-01-01

    Problem Despite widespread acceptance of the Ottawa ankle rules for assessment of acute ankle injuries, their application varies considerably. Design Before and after study. Background and setting Emergency departments of a tertiary teaching hospital and a community hospital in Australia. Key measures for improvement Documentation of the Ottawa ankle rules, proportion of patients referred for radiography, proportion of radiographs showing a fracture. Strategies for change Education, a problem specific radiography request form, reminders, audit and feedback, and using radiographers as “gatekeepers.” Effects of change Documentation of the Ottawa ankle rules improved from 57.5% to 94.7% at the tertiary hospital, and 51.6% to 80.8% at the community hospital (P<0.001 for both). The proportion of patients undergoing radiography fell from 95.8% to 87.2% at the tertiary hospital, and from 91.4% to 78.9% at the community hospital (P<0.001 for both). The proportion of radiographs showing a fracture increased from 20.4% to 27.1% at the tertiary hospital (P=0.069), and 15.2% to 27.2% (P=0.002) at the community hospital. The missed fracture rate increased from 0% to 2.9% at the tertiary hospital and from 0% to 1.6% at the community hospital compared with baseline (P=0.783 and P=0.747). Lessons learnt Assessment of case note documentation has limitations. Clinician groups seem to differ in their capacity and willingness to change their practice. A multifaceted change strategy including a problem specific radiography request form can improve the selection of patients for radiography. PMID:19675080

  17. [Indicator condition guided human immunodeficiency virus requesting in primary health care: results of a collaboration].

    PubMed

    Cayuelas-Redondo, Laia; Menacho-Pascual, Ignacio; Noguera-Sánchez, Pablo; Goicoa-Gago, Carmen; Pollio-Peña, Gernónimo; Blanco-Delgado, Rebeca; Barba-Ávila, Olga; Sequeira-Aymar, Ethel; Muns, Mercè; Clusa, Thais; García, Felipe; León, Agathe

    2015-12-01

    The search of HIV infected patients guided by indicator conditions (IC) is a strategy used to increase the early detection of HIV. The objective is to analyze whether a collaboration to raise awareness of the importance of early detection of HIV in 3 primary care centers influenced the proportion of HIV serology requested. Multicenter retrospective study was conducted comparing the baseline and a post-collaboration period. The collaboration consisted of training sessions and participation in the HIDES study (years 2009-2010). Patients between 18 and 64 years old with newly diagnosed herpes zoster, seborrheic eczema, mononucleosis syndrome, and leucopenia/thrombocytopenia in 3 primary care centers in 2008 (baseline period) and 2012 (post-collaboration period). The sociodemographic variables, HIV risk conditions, requests for HIV serology, and outcomes were evaluated. A total of 1,219 ICs were included (558 in 2008 and 661 in 2012). In 2008 the number of HIV tests in patients with an IC was 3.9%, and rose to 11.8% in 2012 (P<.0001). The HIV infection rate was 2.2% (95% CI: 0.4-7.3) (n=2). It was estimated that 25 new cases (12 in 2008 and 13 in 2012) would have been diagnosed if they had performed the test on all patients with IC. Predictors of HIV request were, having an IC in 2012, a younger age, having an mononucleosis syndrome, and not being Spanish. The HIV request demand tripled, after the collaboration with primary care centers, however in 88% the test was not requested, resulting in diagnostic losses. New strategies are needed to raise awareness of the importance of early detection of HIV. Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  18. A Comparison of PECS and iPad to Teach Requesting to Pre-schoolers with Autistic Spectrum Disorders.

    PubMed

    Agius, May M; Vance, Margaret

    2016-01-01

    Few studies have compared the efficacy of the Picture Exchange Communication System (PECS) and iPads used as speech generating devices (SGDs), and none have targeted preschoolers. This study compares the relative efficacy of PECS and an iPad/SGD with three preschool-aged children with autism spectrum disorder and limited functional speech who lived in Malta. The study utilized an adapted alternating treatment design embedded in a multiple baseline design, with requesting of reinforcers as the dependent variable. Visual analysis of the results indicated that all participants required more prompted trials and sessions for the iPad/SGD condition. All participants learned a three step navigational sequence on the iPad. Participant preference probes were inconclusive and were not linked to speed of acquisition of requesting skills. Results suggest that both PECS and an iPad could be appropriate for teaching requesting skills to beginning communicators.

  19. Baseline budgeting for continuous improvement.

    PubMed

    Kilty, G L

    1999-05-01

    This article is designed to introduce the techniques used to convert traditionally maintained department budgets to baseline budgets. This entails identifying key activities, evaluating for value-added, and implementing continuous improvement opportunities. Baseline Budgeting for Continuous Improvement was created as a result of a newly named company president's request to implement zero-based budgeting. The president was frustrated with the mind-set of the organization, namely, "Next year's budget should be 10 to 15 percent more than this year's spending." Zero-based budgeting was not the answer, but combining the principles of activity-based costing and the Just-in-Time philosophy of eliminating waste and continuous improvement did provide a solution to the problem.

  20. Traffic Aware Strategic Aircrew Requests (TASAR) Concept of Operations

    NASA Technical Reports Server (NTRS)

    Henderson, Jeffrey

    2013-01-01

    Aircrews submit trajectory change requests to air traffic control (ATC) to better achieve the operator's preferred business trajectory. Requests are currently made with limited information and are often denied because the change is not compatible with traffic. Also, request opportunities can be overlooked due to lack of automation that advises aircrews of trajectory changes that improve flight time, fuel burn, and other objectives. The Traffic Aware Strategic Aircrew Requests (TASAR) concept leverages Automatic Dependent Surveillance-Broadcast (ADS-B) surveillance information to advise the aircrew of beneficial trajectory changes that are probed for traffic compatibility prior to issuing the request to ATC. This document describes the features, benefits, and limitations of TASAR automation hosted on an Electronic Flight Bag. TASAR has two modes: (1) auto mode that continuously assesses opportunities for improving the performance of the flight and (2) manual mode that probes trajectory changes entered by aircrews for conflicts and performance objectives. The roles and procedures of the aircrew and ATC remain unchanged under TASAR.

  1. 76 FR 67558 - Proposed Information Collection (Request for Change of Program or Place of Training) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... information needed to determine a claimant's eligibility for continued educational assistance when he or she... use of other forms of information technology. Title: Request for Change of Program or Place of... collection. Abstract: Claimants receiving educational benefits complete VA Form 22-1995 to request a change...

  2. The Challenges in Meeting OSD’s Obligation and Expenditure Rate Goals: A Closer Look at Potential Causal Factors, Their Groupings, and How They Modulate

    DTIC Science & Technology

    2013-10-01

    F22 Defense Contract Audit Agency (DCAA) administrative actions 44% 3.92 2.61 F23 Unplanned Congressional adds to Program Baseline (PB) request 43...materialized F21 Program delays from prerequisite events F22 DCAA administrative actions F23 Unplanned Congressional adds to PB request F24...functional areas (F27) and Tenure of PM and others in key positions (F46); and DCMA administrative actions (F36) and DCAA administrative actions ( F22

  3. A study of the influence of task familiarity on user behaviors and performance with a MeSH term suggestion interface for PubMed bibliographic search.

    PubMed

    Tang, Muh-Chyun; Liu, Ying-Hsang; Wu, Wan-Ching

    2013-09-01

    Previous research has shown that information seekers in biomedical domain need more support in formulating their queries. A user study was conducted to evaluate the effectiveness of a metadata based query suggestion interface for PubMed bibliographic search. The study also investigated the impact of search task familiarity on search behaviors and the effectiveness of the interface. A real user, user search request and real system approach was used for the study. Unlike tradition IR evaluation, where assigned tasks were used, the participants were asked to search requests of their own. Forty-four researchers in Health Sciences participated in the evaluation - each conducted two research requests of their own, alternately with the proposed interface and the PubMed baseline. Several performance criteria were measured to assess the potential benefits of the experimental interface, including users' assessment of their original and eventual queries, the perceived usefulness of the interfaces, satisfaction with the search results, and the average relevance score of the saved records. The results show that, when searching for an unfamiliar topic, users were more likely to change their queries, indicating the effect of familiarity on search behaviors. The results also show that the interface scored higher on several of the performance criteria, such as the "goodness" of the queries, perceived usefulness, and user satisfaction. Furthermore, in line with our hypothesis, the proposed interface was relatively more effective when less familiar search requests were attempted. Results indicate that there is a selective compatibility between search familiarity and search interface. One implication of the research for system evaluation is the importance of taking into consideration task familiarity when assessing the effectiveness of interactive IR systems. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  4. 77 FR 17074 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... information on the effects of these programs on parents and children. This includes investigating the effects... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Proposed...: Baseline survey data collection. OMB No.: 0970-0402. Description: The Administration for Children and...

  5. 78 FR 4906 - International Mail Contracts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... the baseline agreements and that the benefits are comparable. Id. The Postal Service states that...-filed Postal Service request concerning an additional Global Plus 1C contract. This document invites...: January 24, 2013. ADDRESSES: Submit comments electronically via the Commission's Filing Online system at...

  6. 78 FR 41801 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-11

    ... outcomes, the study will also consider the living, employment, education, and family situation of the youth... Survey 15 1 1 15 Youth Baseline Survey 1250 1 0.75 937.50 Youth 6-Month Follow Up 1250 1 0.33 412.50...

  7. 78 FR 52005 - 30-Day Notice of Proposed Information Collection: Multifamily Project Construction Contract...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-21

    ... Construction Contract, Building Loan Agreement, & Construction Change Request AGENCY: Office of the Chief... Information Collection Title of Information Collection: Multifamily Project Construction Contract, Building Loan Agreement, & Construction Change Request. OMB Approval Number: 2502-0011. Type of Request...

  8. Preclinic group education sessions reduce waiting times and costs at public pain medicine units.

    PubMed

    Davies, Stephanie; Quintner, John; Parsons, Richard; Parkitny, Luke; Knight, Paul; Forrester, Elizabeth; Roberts, Mary; Graham, Carl; Visser, Eric; Antill, Tracy; Packer, Tanya; Schug, Stephan A

    2011-01-01

    To assess the effects of preclinic group education sessions and system redesign on tertiary pain medicine units and patient outcomes. Prospective cohort study. Two public hospital multidisciplinary pain medicine units. People with persistent pain. A system redesign from a "traditional" model (initial individual medical appointments) to a model that delivers group education sessions prior to individual appointments. Based on Patient Triage Questionnaires patients were scheduled to attend Self-Training Educative Pain Sessions (STEPS), a two day eight hour group education program, followed by optional patient-initiated clinic appointments. Number of patients completing STEPS who subsequently requested individual outpatient clinic appointment(s); wait-times; unit cost per new patient referred; recurrent health care utilization; patient satisfaction; Global Perceived Impression of Change (GPIC); and utilized pain management strategies. Following STEPS 48% of attendees requested individual outpatient appointments. Wait times reduced from 105.6 to 16.1 weeks at one pain unit and 37.3 to 15.2 weeks at the second. Unit cost per new patient appointed reduced from $1,805 Australian Dollars (AUD) to AUD$541 (for STEPS). At 3 months, patients scored their satisfaction with "the treatment received for their pain" more positively than at baseline (change score=0.88; P=0.0003), GPIC improved (change score=0.46; P<0.0001) and mean number of active strategies utilized increased by 4.12 per patient (P=0.0004). The introduction of STEPS was associated with reduced wait-times and costs at public pain medicine units and increased both the use of active pain management strategies and patient satisfaction. Wiley Periodicals, Inc.

  9. 78 FR 31942 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-28

    ... No.: 0970-0403. Description: The Office of Planning, Research, and Evaluation (OPRE), Administration... critical to informing decisions related to future investments in programming as well as the design and... program applicants)--APPROVED October 31, 2012. (3) Baseline Survey (for RF study participants)--APPROVED...

  10. Effect of fennel vaginal cream on sexual function in postmenopausal women: A double blind randomized controlled trial

    PubMed Central

    Abedi, Parvin; Najafian, Mahin; Yaralizadeh, Masumeh; Namjoyan, Foroogh

    2018-01-01

    Objective: The aim of this study was to assess the effect of fennel on sexual function in postmenopausal women. It was a randomized controlled trial in 60 postmenopausal women with sexual dysfunction who were randomly assigned to two groups receiving either fennel vaginal cream (n=30) or placebo (n=30). Vaginal atrophy in the women was assessed using symptoms such as pallor, dryness, dyspareunia, itching and burning. The pH of the vagina and cytology of the vaginal mucosa were also measured at baseline and 8 weeks after the intervention. All participants were requested to fill out the Female Sexual Function Index (FSFI) at baseline and after 8 weeks. The intervention group was requested to use fennel vaginal cream (5 grams) every night, while the control group used placebo each night for 8 weeks. The data were analyzed using the independent t-test and Chi-square, Mann-Whitney and Wilcoxon tests. All areas of sexual function including arousal, lubrication, orgasm, sexual satisfaction and pain improved in both fennel and placebo groups after 8 weeks; however, the differences in the fennel group were more evident (p<0.05). The total FSFI score was significantly higher in the fennel group compared to the control group (8.2 ±9.4 and 8.03±10.36 before the intervention and changing to 33.79±0.7 and 18.99±1.09 after the intervention in the fennel and placebo groups, respectively; p<0.001). Discussion: According to our results, fennel vaginal cream is an effective means of improving sexual activity in postmenopausal women. The use of this product in women who have sexual dysfunction and contraindications for hormone therapy is recommended. PMID:29696061

  11. High-resolution topographic, bathymetric, and oceanographic data for the Pleasure Point Area, Santa Cruz County, California: 2005-2007

    USGS Publications Warehouse

    Storlazzi, Curt D.; Barnard, Patrick L.; Collins, Brian D.; Finlayson, David P.; Golden, Nadine E.; Hatcher, Gerry A.; Kayen, Robert E.; Ruggiero, Peter

    2007-01-01

    The County of Santa Cruz Department of Public Works and the County of Santa Cruz Redevelopment Agency requested the U.S. Geological Survey (USGS) Western Coastal and Marine Geology Team (WCMG) to provide baseline geologic and oceanographic information on the coast and inner shelf at Pleasure Point, Santa Cruz County, California. The rationale for this proposed work is a need to better understand the environmental consequences of a proposed bluff stabilization project on the beach, the nearshore and the surf at Pleasure Point, Santa Cruz County, California. To meet these information needs, the USGS-WCMG Team collected baseline scientific information on the morphology and waves at Pleasure Point. This study provided high-resolution topography of the coastal bluffs and bathymetry of the inner shelf off East Cliff Drive between 32nd Avenue and 41st Avenue. The spatial and temporal variation in waves and their breaking patterns at the study site were documented. Although this project did not actively investigate the impacts of the proposed bluff stabilization project, these data provide the baseline information required for future studies directed toward predicting the impacts of stabilization on the sea cliffs, beach and nearshore sediment profiles, natural rock reef structures, and offshore habitats and resources. They also provide a basis for calculating potential changes to wave transformations into the shore at Pleasure Point.

  12. 30 CFR 585.610 - What must I include in my SAP?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... offshore and onshore. (6) General structural and project design, fabrication, and installation Information... requested by BOEM. (b) You must provide the results of geophysical and geological surveys, hazards surveys, archaeological surveys (if required), and baseline collection studies (e.g., biological) with the supporting data...

  13. 30 CFR 585.610 - What must I include in my SAP?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... offshore and onshore. (6) General structural and project design, fabrication, and installation Information... requested by BOEM. (b) You must provide the results of geophysical and geological surveys, hazards surveys, archaeological surveys (if required), and baseline collection studies (e.g., biological) with the supporting data...

  14. 30 CFR 585.610 - What must I include in my SAP?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... offshore and onshore. (6) General structural and project design, fabrication, and installation Information... requested by BOEM. (b) You must provide the results of geophysical and geological surveys, hazards surveys, archaeological surveys (if required), and baseline collection studies (e.g., biological) with the supporting data...

  15. 77 FR 31866 - Intent To Request Approval From OMB of One New Public Collection of Information: Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... (BASE) Program for Public Transportation Systems AGENCY: Transportation Security Administration, DHS. ACTION: 60-day Notice. SUMMARY: The Transportation Security Administration (TSA) invites public comment... under contract with a public transportation agency. \\1\\ TSA, ``Transportation Sector-Specific Plan Mass...

  16. 75 FR 22575 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... impact of the PITC on child care quality and children's development. The evaluation is conducted by... children's language, social and cognitive development. Baseline data collection took place 2007; follow-up... Review: Extension. Title: Study of the Program for Infant Toddler Care. Frequency: Once. Affected Public...

  17. 77 FR 24481 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... Power North, LLC. Description: Silver State Solar Power North LLC Baseline Tariff Amendment to be... Market Power Update of CPV Batesville, LLC. Filed Date: 3/21/12. Accession Number: 20120321-5067...: ER12-799-000. Applicants: Nevada Solar One, LLC. Description: Supplement to Request for Determination...

  18. 77 FR 4287 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... other will not have experienced the feature (``control''). Average test scores of the two groups will... Promising Features of Teacher Preparation Programs; Phase 1--Recruitment. OMB Control Number: 1850-NEW... baseline student achievement test for an experimental study of the effect on student learning of teachers...

  19. 76 FR 36583 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... Docket No. CP2010-36 serve as the baseline contract for future functional equivalence analyses of the... commitments, do not alter the contract's functional equivalency. Id. at 4. The Postal Service asserts that... offered or the fundamental structure of the contract. Therefore, it requests that the instant contract be...

  20. 75 FR 9189 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... mandated standardized test scores); follow-up surveys for students; teacher and parent rating/observation on various student aspects (e.g., student social skills); baseline and follow-up surveys for teachers... Character (LIC) program. This study is based on an experimental design that utilizes the random assignment...

  1. NCO Production Management Branch

    Science.gov Websites

    Climate Climate Prediction Climate Archives Weather Safety Storm Ready NOAA Central Library Photo Library Management Branch Production Management Branch About the Production Management Branch NCO REQUEST FOR CHANGE (RFC) DATABASE ACCESS NCO Request For Change (RFC) Archive [For INTERNAL Use Only] NCO Request For

  2. 75 FR 33584 - Request for Comments on Proposed Changes to Restriction Practice in Patent Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... DEPARTMENT OF COMMERCE United States Patent and Trademark Office [Docket No.: PTO-P-2010-0030] Request for Comments on Proposed Changes to Restriction Practice in Patent Applications AGENCY: United States Patent and Trademark Office, Commerce. ACTION: Request for comments. SUMMARY: In situations in...

  3. Impact of worktime arrangements on work-home interference among Dutch employees.

    PubMed

    Jansen, Nicole W H; Kant, Ijmert; Nijhuis, Frans J N; Swaen, Gerard M H; Kristensen, Tage S

    2004-04-01

    This study examined the effects of different worktime arrangements on work-home interference while taking into account other work-related factors, private situation and health status, explored gender differences in this relation, and examined reciprocal effects between workhours and work-home interference. Data from the Maastricht cohort study on fatigue at work were used with 8 months of follow-up (N=6947 at baseline). Worktime arrangements were related to work-home interference among the men and women, even after control for confounding. As compared with daywork, baseline shiftwork was associated with higher work-home interference over time. Within daywork, full-time work was prospectively related to higher work-home interference than part-time work was. For full-timers, baseline overtime work, hours of overtime work, change in number of workhours, and commuting time were related to higher work-home interference over time, whereas compensation for overtime work, familiarity with work roster, ability to take a day off, and a decrease in workhours at own request were associated with less work-home interference. For the part-timers, baseline overtime work and commuting time were related to higher work-home interference over time, whereas compensation for overtime, flexible workhours, and ability to take a day off were protective against work-home interference. Reciprocal relations between work-home interference and workhours were also found. Worktime arrangements are clearly related to work-home interference. Because reciprocal effects exist as well, important selection processes may exist. Nevertheless, specific characteristics of worktime arrangements could constitute useful tools for reducing work-home interference.

  4. Decision Making and Communications Process Assessment of NASA Using Three Change Requests from the Space Launch System Program

    NASA Technical Reports Server (NTRS)

    Hicks, Karen Campbell

    2015-01-01

    This thesis investigated the communication and decision making process as part of the Systems Engineering practices at the NASA/Marshall Center to determine its level of effectiveness. Data was collected across three change requests to assess how decisions were made, how the decisions were communicated, and whether a process mattered in the formulation and dissemination of those decisions. Data results revealed the comprehensive decision making process for the technical change requests to be effective. Evidence revealed that the process was sufficiently tailored to accommodate the need of each individual technical change which promoted effective communication amongst the stakeholders in the formulation of the strategic decision recommendations elevated to upper management. However, data results also revealed the dissemination of the final decision and approval of the change requests from the higher organizational level down to all stakeholders was less effective. An establishment of a culmination meeting at the end of the change request decision process in which to close the communication loop with all entities would be beneficial.

  5. Advanced Strategic and Tactical Relay Request Management for the Mars Relay Operations Service

    NASA Technical Reports Server (NTRS)

    Allard, Daniel A.; Wallick, Michael N.; Gladden, Roy E.; Wang, Paul; Hy, Franklin H.

    2013-01-01

    This software provides a new set of capabilities for the Mars Relay Operations Service (MaROS) in support of Strategic and Tactical relay, including a highly interactive relay request Web user interface, mission control over relay planning time periods, and mission management of allowed strategic vs. tactical request parameters. Together, these new capabilities expand the scope of the system to include all elements critical for Tactical relay operations. Planning of replay activities spans a time period that is split into two distinct phases. The first phase is called Strategic, which begins at the time that relay opportunities are identified, and concludes at the point that the orbiter generates the flight sequences for on board execution. Any relay request changes from this point on are called Tactical. Tactical requests, otherwise called Orbit - er Relay State Changes (ORSC), are highly restricted in terms of what types of changes can be made, and the types of parameters that can be changed may differ from one orbiter to the next. For example, one orbiter may be able to delay the start of a relay request, while another may not. The legacy approach to ORSC management involves exchanges of e-mail with "requests for change" and "acknowledgement of approval," with no other tracking of changes outside of e-mail folders. MaROS Phases 1 and 2 provided the infrastructure for strategic relay for all supported missions. This new version, 3.0, introduces several capabilities that fully expand the scope of the system to include tactical relay. One new feature allows orbiter users to manage and "lock" Planning Periods, which allows the orbiter team to formalize the changeover from Strategic to Tactical operations. Another major feature allows users to interactively submit tactical request changes via a Web user interface. A third new feature allows orbiter missions to specify allowed tactical updates, which are automatically incorporated into the tactical change process. This software update is significant in that it provides the only centralized service for tactical request management available for relay missions.

  6. 77 FR 31632 - Intent To Request Approval From OMB of One New Public Collection of Information: Highway Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... and assets owned and operated by state departments of education and transportation. The Highway BASE... Transportation (DOT), Federal Motor Carrier Safety Administration (FMCSA), school bus, motorcoach companies... consistent road map for highway systems to address security and emergency program vulnerabilities. In...

  7. 76 FR 2124 - Agency Information Collection Activities; Proposed Collection; Comment Request; Voluntary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... (original and update), and verification audit; names of the person(s) who completed the self-assessment... of the self assessment, date of the verification audit report, name of the auditor, signature and... self assessment, (2) conducting a baseline survey of the regulated industry, and (3) obtaining an...

  8. 75 FR 79053 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... POSTAL REGULATORY COMMISSION [Docket Nos. MC2011-7, CP2011-39 and CP2011-40; Order No. 607] New... Service seeks to add Global Plus 1B as a new product, to the competitive product list.\\1\\ The Request has... instant contracts be considered ``the new `baseline' contracts for future functional equivalency analyses...

  9. 75 FR 471 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ...' Decision No. 08-10, the Postal Service submitted a description of Global Direct Contracts which it... take the place of its immediate predecessor and one of the original baseline Global Direct Contracts, the contract in Docket No. CP2009-11, the Postal Service requests that the instant contract be treated...

  10. 76 FR 41805 - Submission for OMB Review; Comment Request; Prostate, Lung, Colorectal and Ovarian Cancer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... baseline, will be used to assure comparability between the screening and control groups and make... control number. Proposed Collection: Title: Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial... and instruments, contact Dr. Christine D. Berg, Chief, Early Detection Research Group, National Cancer...

  11. 78 FR 58309 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... initiative, funded by the Children's Bureau (CB) within ACF, will support planning grants to develop a model... for the process evaluation will be used to assess grantees' organizational capacity and readiness to... response burden hours Baseline Telephone Interview of 540 270 1 1.0 270 Organizational Readiness...

  12. 75 FR 32947 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... interviews include 11 questions and will take approximately 60 minutes to complete. These follow-up... readiness within which a community must progress through. CRAs include 26 interview questions which address... Collection Activities--Tier I GONA--Baseline Interviews (1 Version). Each participating community will have...

  13. 39 CFR 3001.72 - Filing of formal requests.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Requests for Changes in the Nature of Postal Services § 3001.72 Filing of formal requests. Whenever the... in the nature of postal services subject to this subpart, the Postal Service shall file with the... Postal Service proposes to make effective the change in the nature of postal services involved. Within 5...

  14. Methoxyflurane Analgesia in Adult Patients in the Emergency Department: A Subgroup Analysis of a Randomized, Double-blind, Placebo-controlled Study (STOP!).

    PubMed

    Coffey, Frank; Dissmann, Patrick; Mirza, Kazim; Lomax, Mark

    2016-11-01

    Acute pain remains highly prevalent in the Emergency Department (ED) setting. This double-blind, randomized, placebo-controlled UK study investigated the efficacy and safety of low-dose methoxyflurane analgesia for the treatment of acute pain in the ED in the adult population of the STOP! trial. Patients presenting to the ED requiring analgesia for acute pain (pain score of 4-7 on the Numerical Rating Scale) due to minor trauma were randomized in a 1:1 ratio to receive methoxyflurane (up to 6 mL) or placebo (normal saline), both via a Penthrox ® (Medical Developments International Limited, Scoresby, Australia) inhaler. Rescue medication (paracetamol/opioids) was available immediately upon request. Change from baseline in visual analog scale (VAS) pain intensity was the primary endpoint. 300 adult and adolescent patients were randomized; data are presented for the adult subgroup (N = 204). Mean baseline VAS pain score was ~66 mm in both groups. The mean change from baseline to 5, 10, 15 and 20 min was greater for methoxyflurane (-20.7, -27.4, -33.3 and -34.8 mm, respectively) than placebo (-8.0, -11.1, -12.3 and -15.2 mm, respectively). The primary analysis showed a highly significant treatment effect overall across all four time points (-17.4 mm; 95% confidence interval: -22.3 to -12.5 mm; p < 0.0001). Median time to first pain relief was 5 min with methoxyflurane [versus 20 min with placebo; (hazard ratio: 2.32; 95% CI: 1.63, 3.30; p < 0.0001)]; 79.4% of methoxyflurane-treated patients experienced pain relief within 1-10 inhalations. 22.8% of placebo-treated patients requested rescue medication within 20 min compared with 2.0% of methoxyflurane-treated patients (p = 0.0003). Methoxyflurane treatment was rated 'Excellent', 'Very Good' or 'Good' by 77.6% of patients, 74.5% of physicians and 72.5% of nurses. Treatment-related adverse events (mostly dizziness/headache) were reported by 42.2% of patients receiving methoxyflurane and 14.9% of patients receiving placebo; none caused withdrawal and the majority were mild and transient. The results of this study support the evidence from previous trials that low-dose methoxyflurane administered via the Penthrox inhaler is a well-tolerated, efficacious and rapid-acting analgesic. Medical Developments International (MDI) Limited and Mundipharma Research GmbH & Co.KG. Clinicaltrials.gov identifier: NCT01420159, EudraCT number: 2011-000338-12.

  15. Structured education can improve primary-care management of headache: the first empirical evidence, from a controlled interventional study.

    PubMed

    Braschinsky, Mark; Haldre, Sulev; Kals, Mart; Iofik, Anna; Kivisild, Ave; Korjas, Jaanus; Koljal, Silvia; Katsarava, Zaza; Steiner, Timothy J

    2016-01-01

    Headache disorders are under-recognized and under-diagnosed. A principal factor in their suboptimal management is lack of headache-related training among health-care providers, especially in primary care. In Estonia, general practitioners (GPs) refer many headache patients to neurological specialist services, mostly unnecessarily. GPs request "diagnostic" investigations, which are usually unhelpful and therefore wasteful. GP-made headache diagnoses are often arcane and non-specific, and treatments based on these are inappropriate. The aim of this study was to develop, implement and test an educational model intended to improve headache-related primary health care in Estonia. This was a controlled study consisting of baseline observation, intervention and follow-up observation using the same measures of effect. It involved six GPs in Põlva and the surrounding region in Southern Estonia, together with their future patients presenting consecutively with headache as their main complaint, all with their consent. The primary outcome measure was referral rate (RR) to neurological specialist services. Secondary measures included number of GP-requested investigations, GP-made headache diagnoses and how these conformed to standard terminology (ICD-10), and GP-recommended or initiated treatments. RR at baseline (n = 490) was 39.5 %, falling to 34.7 % in the post-intervention group (n = 295) (overall reduction 4.8 %; p = 0.21). In the large subgroup of patients (88 %) for whom GPs made clearly headache-related ICD-10 diagnoses, RR fell by one fifth (from 40 to 32 %; p = 0.08), but the only diagnosis-related RR that showed a statistically significant reduction was (pericranial) myalgia (19 to 3 %; p = 0.03). There was a significant increase towards use of more specific diagnoses. Use of investigations in diagnosing headache reduced from 26 to 4 % (p < 0.0001). Initiation of treatment by GPs increased from 58 to 81 % (p < 0.0001). These were modest changes in GPs' entrenched behaviour. Nevertheless they were empirical evidence that GPs' practice in the field of headache could be improved by structured education. Furthermore, the changes were likely to be cost-saving. To our knowledge this study is the first to produce such evidence.

  16. The Development of Referential Communication and Autism Symptomatology in High-Risk Infants

    PubMed Central

    Ibañez, Lisa V.; Grantz, Caroline J.; Messinger, Daniel S.

    2013-01-01

    Non-verbal referential communication is impaired in children with Autism Spectrum Disorders (ASD). However, the development of difficulties with referential communication in the younger siblings of children with ASD (High-Risk Siblings)—and the degree to which early referential communication predicts later autism symptomatology—is not clear. We modeled the early developmental trajectories of three types of referential communication: responding to joint attention (RJA), initiating joint attention (IJA), and initiating behavioral requests (IBR) across 8, 10, 12, 15, and18 months of age in High-Risk Siblings (n = 40) and the infant siblings of children without ASD (Low-Risk Siblings; n = 21). Hierarchical Linear Modeling indicated that High-Risk Siblings exhibited lower levels of baseline RJA and IJA and a lower rate of linear change in IBR than Low-Risk Siblings. When the 10 High-Risk Siblings who received an ASD diagnosis were excluded from analyses, group differences in the development of referential communication remained significant only for RJA. Baseline levels of IJA were associated with later ASD symptomatology among High-Risk Siblings, suggesting that individual differences in referential communication development at 8 months may index early manifestations of ASD. PMID:24403864

  17. 33 CFR 117.35 - Temporary change to a drawbridge operating schedule.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... District Commander for approval of the change. (2) The request must describe the reason for the closure and... receipt of the request. If the request is denied, the reasons for the denial will be set out in the... broken into separate time periods on the same day or on consecutive days, the drawbridge must provide...

  18. 75 FR 33886 - Proposed Collection; Comment Request for Form 5308

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ..., Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently, the IRS is soliciting comments concerning Form 5308, Request for Change in Plan/Trust Year. DATES: Written comments should be received on or before... INFORMATION: Title: Request for Change in Plan/Trust Year. OMB Number: 1545-0201. Form Number: 5308. Abstract...

  19. 78 FR 57372 - Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ... p.m. Requests to speak at one or more public scoping meeting(s) should be received at the address... ADDRESSES section. ADDRESSES: Requests to speak at a public scoping meeting(s), and requests for individuals... Impact Statement: Announcement of Change in Public Meeting Location AGENCY: Department of Energy. ACTION...

  20. Towards estimates of future rainfall erosivity in Europe based on REDES and WorldClim datasets

    NASA Astrophysics Data System (ADS)

    Panagos, Panos; Ballabio, Cristiano; Meusburger, Katrin; Spinoni, Jonathan; Alewell, Christine; Borrelli, Pasquale

    2017-05-01

    The policy requests to develop trends in soil erosion changes can be responded developing modelling scenarios of the two most dynamic factors in soil erosion, i.e. rainfall erosivity and land cover change. The recently developed Rainfall Erosivity Database at European Scale (REDES) and a statistical approach used to spatially interpolate rainfall erosivity data have the potential to become useful knowledge to predict future rainfall erosivity based on climate scenarios. The use of a thorough statistical modelling approach (Gaussian Process Regression), with the selection of the most appropriate covariates (monthly precipitation, temperature datasets and bioclimatic layers), allowed to predict the rainfall erosivity based on climate change scenarios. The mean rainfall erosivity for the European Union and Switzerland is projected to be 857 MJ mm ha-1 h-1 yr-1 till 2050 showing a relative increase of 18% compared to baseline data (2010). The changes are heterogeneous in the European continent depending on the future projections of most erosive months (hot period: April-September). The output results report a pan-European projection of future rainfall erosivity taking into account the uncertainties of the climatic models.

  1. Towards estimates of future rainfall erosivity in Europe based on REDES and WorldClim datasets.

    PubMed

    Panagos, Panos; Ballabio, Cristiano; Meusburger, Katrin; Spinoni, Jonathan; Alewell, Christine; Borrelli, Pasquale

    2017-05-01

    The policy requests to develop trends in soil erosion changes can be responded developing modelling scenarios of the two most dynamic factors in soil erosion, i.e. rainfall erosivity and land cover change. The recently developed Rainfall Erosivity Database at European Scale (REDES) and a statistical approach used to spatially interpolate rainfall erosivity data have the potential to become useful knowledge to predict future rainfall erosivity based on climate scenarios. The use of a thorough statistical modelling approach (Gaussian Process Regression), with the selection of the most appropriate covariates (monthly precipitation, temperature datasets and bioclimatic layers), allowed to predict the rainfall erosivity based on climate change scenarios. The mean rainfall erosivity for the European Union and Switzerland is projected to be 857 MJ mm ha -1  h -1  yr -1 till 2050 showing a relative increase of 18% compared to baseline data (2010). The changes are heterogeneous in the European continent depending on the future projections of most erosive months (hot period: April-September). The output results report a pan-European projection of future rainfall erosivity taking into account the uncertainties of the climatic models.

  2. COMPONENT COMMANDS

    Science.gov Websites

    EMERGENCY PREPAREDNESS CONTACT REQUEST A SPEAKER REQUEST A COLOR GUARD OPERATIONAL CONTRACT SUPPORT every two years and makes recommendations to the President, through the Secretary of Defense, on changes Preparedness Contact Request A Speaker Request A Color Guard Stay Connected Privacy & Security Inspector

  3. 76 FR 73777 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... historical baseline is used to set the dividend rate for the next quarter. Affected Public: Banks and lending..., Public Law 104-13, on or after the date of publication of this notice. DATES: Comments should be received..., a bank is required to submit a Supplemental Report each quarter. The Supplemental Report serves two...

  4. 77 FR 27460 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... combined. Individuals will be randomly assigned to a treatment or control group at each site. Data for the..., and 36 months. The 6-month survey is intended to gather information from treatment and control group.... Respondents: Study participants in the treatment and control groups will respond to the baseline and follow-up...

  5. 76 FR 80908 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... for 25 baseline interviews for the respondents participating in the In-situ study at location 1 (30...) responses for 25 In-situ survey participants (670 responses per person) at location 1 (3 minutes per...). Total Responses for Year 2: 18,475. Year 3 8,250 (estimated) responses for 25 In-situ survey respondents...

  6. 75 FR 41177 - Protection of Stratospheric Ozone: Request for Methyl Bromide Critical Use Exemption Applications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... this will be the state's agriculture or environmental protection agency) to receive information about.... Government (through EPA, Department of State, U.S. Department of Agriculture, and other interested Federal... baseline year, the U.S. consumption was approximately 25,500 metric tons of methyl bromide. In 2010, the...

  7. Age and Sex Differences in Children's Responses to Babies: Effects of Adult's Caretaking Requests and Instructions.

    ERIC Educational Resources Information Center

    Berman, Phyllis W.; Goodman, Vickie

    1984-01-01

    In a double-baseline design, children were observed first after being asked to take care of a baby then after watching a male or female adult demonstrate appropriate interactions with the baby. Younger and older day care children (between 30 and 63 months old) participated. (Author/RH)

  8. 76 FR 9356 - Intent To Request Approval From OMB of One New Public Collection of Information: Baseline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... during site visits with security and operating officials of transit systems. The STSIs capture and... assessments during site visits with security and operating officials of transit agencies. DATES: Send your... distance passenger railroad providers operate in the United States.\\1\\ Mass transit and passenger rail...

  9. Using an adapted form of the picture exchange communication system to increase independent requesting in deafblind adults with learning disabilities.

    PubMed

    Bracken, Maeve; Rohrer, Nicole

    2014-02-01

    The current study assessed the effectiveness of an adapted form of the Picture Exchange Communication System (PECS) in increasing independent requesting in deafblind adults with learning disabilities. PECS cards were created to accommodate individual needs, including adaptations such as enlarging photographs and using swelled images which consisted of images created on raised line drawing paper. Training included up to Phase III of PECS and procedures ensuring generalizations across individuals and contexts were included. The effects of the intervention were evaluated using a multiple baseline design across participants. Results demonstrated an increase in independent requesting with each of the participants reaching mastery criterion. These results suggest that PECS, in combination with some minor adaptations, may be an effective communicative alternative for individuals who are deafblind and have learning impairments. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Patient Awareness and Expectations of Pharmacist Services During Hospital Stay.

    PubMed

    King, Philip K; Martin, Steven J; Betka, Eric M

    2017-10-01

    There are insufficient data in the United States regarding patient awareness and expectations of hospital pharmacist availability and services. The objective of this research is to assess patient awareness and expectations of hospital pharmacist services and to determine whether a marketing campaign for pharmacist services increases patient awareness and expectations. Eligible inpatients were surveyed before and after implementation of a hospital-wide pharmacist services marketing campaign (12 items; Likert scale of 1 [strongly disagree] to 4 [strongly agree]; maximum total score of 48) regarding awareness of pharmacist services. The primary outcome was the change in median total survey scores from baseline. Other outcomes included the frequency of patient requests for pharmacists. Similar numbers of patients completed the survey before and after the campaign (intervention, n = 140, vs control, n = 147). Awareness of pharmacist availability and services was increased (41 [interquartile ranges, IQRs: 36-46] vs 37 [IQR 31-43]; P < .001). Patients were 7 times more likely to request a pharmacist following the marketing campaign implementation. Awareness among inpatients of pharmacist services is low. Marketing pharmacist availability and services to patients in the hospital improves awareness and expectations for pharmacist-provided care and increases the frequency of patient-initiated interaction between pharmacists and patients. This could improve patient outcomes as pharmacists become more integrally involved in direct patient care.

  11. Science supporting Gulf of Mexico oil-spill response, mitigation, and restoration activities-Assessment, monitoring, mapping, and coordination

    USGS Publications Warehouse

    Kindinger, Jack; Tihansky, Ann B.; Cimitile, Matthew

    2011-01-01

    The St. Petersburg Coastal and Marine Science Center of the U.S. Geological Survey (USGS) investigates physical processes related to coastal and marine environments and societal implications related to natural hazards, resource sustainability, and environmental change. Immediately after the Deepwater Horizon event, the USGS began responding to data requests, directing response personnel, and providing coastal and shelf geophysical data to coastal-resource managers. The USGS provided oil-spill responders with up-to-date coastal bathymetry, geologic data, and maps characterizing vulnerability and levels of risk from potential spill impacts in Louisiana, Mississippi, and Alabama. Baseline conditions prior to any spill impacts were documented through programs that included shoreline sampling and sediment coring from east Texas to the east coast of Florida and aerial photography of many environmentally sensitive Gulf coastal areas. The USGS responded to numerous verbal and written data requests from Federal, State, and local partners and academic institutions with USGS scientific staff participating in the Coast Guard Unified Commands (UC) and Operational Science Advisory Teams (OSAT). The USGS conducted technical review of reports and plans for many response activities. Oil-spill responders, managers, and personnel on the ground, including partners such as the National Park Service, Gulf Islands National Seashore, Chandeleur Islands Refuge, and State agencies, continue to rely on USGS products.

  12. Epoch of Reionisation

    NASA Astrophysics Data System (ADS)

    Barry, N.; Beardsley, A.; Bowman, J.; Briggs, F.; Byrne, R.; Carroll, P.; Hazelton, B.; Jacobs, D.; Jordan, C.; Kittiwisit, P.; Lanman, A.; Lenc, E.; Li, W.; Line, J.; McKinley, B.; Mitchell, D.; Morales, M.; Murray, S.; Paul, S.; Pindor, B.; Pober, J.; Rahimi, M.; Riding, J.; Sethi, S.; Shankar, U.; Subrahmanyan, R.; Sullivan, I.; Takahashi, K.; Thyagarajan, N.; Tingay, S.; Trott, C.; Wayth, R.; Webster, R.; Wyithe, S.

    2017-01-01

    The Murchison Widefield Array is designed to measure the fluctuations in the 21cm emission from neutral hydrogen during the Epoch of Reionisation. The new hex configuration is explicitly designed to test the predicted increase in sensitivity of redundant baselines. However the challenge of the new array is to understand calibration with the new configuration. We have developed two new pipelines to reduce the hex data, and will compare the results with previous datasets from the Phase 1 array. We have now processed 80 hours of data refining the data analysis through our two established Phase 1 pipelines. This proposal requests as much observing time as possible in semester 2017-A to (1) obtain a comparable hex dataset to test the sensitivity and systematic limits with redundant arrays, (2) establish the optimal observing strategy for an EoR detection, and (3) continue to explore observational strategies in the three EoR fields to advise the design of SKA-low experiments. Due to the proposed changes in the array during the upcoming semester, we have not requested a specific number of hours, but will optimise our observing program as availability of the telescope becomes clear. We note that this observing proposal implements the key scientific program that can benefit from the new hex configuration.

  13. Randomised controlled trial of routine individual feedback to improve rationality and reduce numbers of test requests.

    PubMed

    Winkens, R A; Pop, P; Bugter-Maessen, A M; Grol, R P; Kester, A D; Beusmans, G H; Knottnerus, J A

    1995-02-25

    Feedback can be described as a way to provide information on doctors' performance to enable changes in future behaviour. Feedback is used with the aim of changing test-ordering behaviour. It can lead to reductions in test usage and cost savings. It is not sufficiently clear, however, whether feedback leads to more appropriate test use. Since 1985, the Diagnostic Coordinating Center Maastricht has been giving feedback on diagnostic tests as a routine health care activity to all family doctors in its region. Both quantity and quality of requests are discussed. In a randomised, controlled trial over 2.5 years, discussion of tests not included previously was added to the existing routine feedback. One group of family doctors (n = 39) received feedback on test-group A (electrocardiography, endoscopy, cervical smears, and allergy tests), the other (n = 40) on test-group B (radiographic and ultrasonographic tests). Thus, each group of doctors acted as a control group for the other. Changes in volume and rationality of requests were analysed. The number of requests decreased during the trial (p = 0.036). Request numbers decreased particularly for test-group A (p = 0.04). The proportion of requests that were non-rational decreased more in the intervention than in the control groups (p = 0.009). Rationality improved predominantly for test-group B (p = 0.043). Thus, routine feedback can change the quantity and quality of requests.

  14. From Advance Euthanasia Directive to Euthanasia: Stable Preference in Older People?

    PubMed

    Bolt, Eva E; Pasman, H Roeline W; Deeg, Dorly J H; Onwuteaka-Philipsen, Bregje D

    2016-08-01

    To determine whether older people with advance directive for euthanasia (ADEs) are stable in their advance desire for euthanasia in the last years of life, how frequently older people with an ADE eventually request euthanasia, and what factors determine this. Mortality follow-back study nested in a cohort study. The Netherlands. Proxies of deceased members of a cohort representative of Dutch older people (n = 168) and a cohort of people with advance directives (n = 154). Data from cohort members (possession of ADE) combined with after-death proxy information on cohort members' last 3 months of life. Multiple logistic regression analysis was performed on determinants of a euthanasia request in individuals with an ADE. Response rate was 65%. One hundred forty-two cohort members had an ADE at baseline. Three months before death, 87% remained stable in their desire for euthanasia; 47% eventually requested euthanasia (vs 6% without an ADE), and 16% died after euthanasia. People with an ADE were more likely to request euthanasia if they worried about loss of dignity. The majority of older adults who complete an ADE will have a stable preference over time, but an advance desire for euthanasia does not necessarily result in a euthanasia request. Writing an ADE may reflect a person's need for reassurance that they can request euthanasia in the future. © 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

  15. Method and apparatus for granting processors access to a resource

    DOEpatents

    Blumrich, Matthias A.; Salapura, Valentina

    2010-03-16

    An apparatus and method for granting one or more requesting entities access to a resource in a predetermined time interval. The apparatus includes a first circuit receiving one or more request signals, and implementing logic for assigning a priority to the one or more request signals, and, generating a set of first_request signals based on the priorities assigned. One or more priority select circuits for receiving the set of first_request signals and generating corresponding one or more fixed grant signals representing one or more highest priority request signals when asserted during the predetermined time interval. A second circuit device receives the one or more fixed grant signals generates one or more grant signals associated with one or more highest priority request signals assigned, the grant signals for enabling one or more respective requesting entities access to the resource in the predetermined time interval, wherein the priority assigned to the one or more request signals changes each successive predetermined time interval. In one embodiment, the assigned priority is based on a numerical pattern, the first circuit changing the numerical pattern with respect to the first_request signals generated at each successive predetermined time interval.

  16. 19 CFR 181.96 - Change in status of transaction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Change in status of transaction. Each person submitting a request for an advance ruling in connection... described in the advance ruling request as prospective becomes current and under the jurisdiction of a...

  17. 19 CFR 181.96 - Change in status of transaction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Change in status of transaction. Each person submitting a request for an advance ruling in connection... described in the advance ruling request as prospective becomes current and under the jurisdiction of a...

  18. 77 FR 58364 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ..., proposes to extend without changes for three years the Form DOE-887, ``DOE Customer Surveys'' with the... Collection Request Title: ``DOE Customer Surveys;'' (3) Type of Request: Three-year extension without changes; [[Page 58365

  19. 39 CFR 3001.71 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Requests for Changes in the Nature of Postal Services § 3001.71 Applicability. The rules in this subpart... requesting from the Commission an advisory opinion on changes in the nature of postal services which will...

  20. Implementing a reward and reminder underage drinking prevention program in convenience stores near Southern California American Indian reservations.

    PubMed

    Moore, Roland S; Roberts, Jennifer; McGaffigan, Richard; Calac, Daniel; Grube, Joel W; Gilder, David A; Ehlers, Cindy L

    2012-09-01

    Underage drinking is associated with a number of social and public health consequences. Preventing access to alcohol is one approach to reducing underage drinking. This study assesses the efficacy of a culturally tailored "reward and reminder" program aimed at reducing convenience store alcohol sales to youth living on or near nine American Indian reservations. First, tribal council proclamations were sought to support underage drinking prevention, including reward and reminder efforts. Then, decoys (volunteers over 21 years of age but judged to look younger) attempted to purchase alcohol without identification. Clerks who asked for identification were given "rewards" (gift cards and congratulatory letters), whereas clerks who did not were given "reminders" of the law regarding sales to minors. Following an initial baseline of 12 purchase attempts, three repeated reward and reminder visits were made to 13 convenience stores selling alcohol within 10 miles of the reservations (n = 51 total attempts). Five of nine tribal councils passed resolutions in support of the program. The baseline sales rate without requesting ID was 33%. Similarly, 38% of stores in the first reward and reminder visit round failed to request identification. However, in the following two reward and reminder rounds, 0% of the stores failed to request identification. These results indicate that environmental community-level underage drinking prevention strategies to reduce alcohol sales near rural reservations are feasible and can be effective. Environmental prevention strategies within reservation communities support integrated supply and demand reduction models for reducing underage drinking.

  1. Fertility preservation: a challenge for IVF-clinics.

    PubMed

    Dahhan, Taghride; Mol, Femke; Kenter, Gemma G; Balkenende, Eva M E; de Melker, Annemieke A; van der Veen, Fulco; Dancet, Eline A F; Goddijn, Mariëtte

    2015-11-01

    Acute fertility preservation for women is an interdisciplinary treatment that requires adequate information provision and early referral. This quality management project aimed to improve fertility preservation care by using a practical tool: Strengths, Weaknesses, Opportunities and Threats (SWOT) analysis. Quality management project was executed between May 2011 and July 2013. This project has been executed in a university affiliated IVF-clinic in cooperation with two oncological sites and used a four-step strategy: (1) monitoring baseline referral process, (2) exploring baseline fertility preservation program by Strengths, Weaknesses, Opportunities and Threats' (SWOT)-analysis, (3) setting up a new fertility preservation program and (4) evaluating the new fertility preservation program by means of SWOT-analysis. During the three-months monitoring period, fertility preservation was requested for a total of 126 women. The mean age of the women was 33.8 years old (range 1-42 years old). Most requests came from women who wanted to cryopreserve oocytes because of age-related decline of fertility (n=90; 71%). Most requests for acute fertility preservation concerned women with breast cancer (n=16; 57%). Information leaflets and pre-consultation questionnaires for women improved the quality of first fertility preservation consultation as evaluated by final SWOT-analysis. Collaboration with oncological centres and information about fertility preservation improved the referral process. SWOT-analysis proved useful for setting up a new fertility preservation-program and can be recommended as a tool to improve the management and organisation of new types of reproductive care. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  2. 78 FR 58608 - Proposed Collection; Comment Request for the EFTPS Primary Contact Information Change Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... EFTPS Primary Contact Information Change Form AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning the EFTPS Primary Contact Information Change Form. DATES... Constitution Avenue NW., Washington, DC 20224. FOR FURTHER INFORMATION CONTACT: Requests for additional...

  3. 75 FR 61245 - Proposed Collection; Comment Request for the EFTPS Primary Contact Information Change Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... EFTPS Primary Contact Information Change Form AGENCY: Internal Revenue Service (IRS), Treasury. ACTION..., the IRS is soliciting comments concerning the EFTPS Primary Contact Information Change Form. DATES... Constitution Avenue, NW., Washington, DC 20224. FOR FURTHER INFORMATION CONTACT: Requests for additional...

  4. 78 FR 341 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ..., Parkersburg, WV 26106-1328, (304) 480-8150. SUPPLEMENTARY INFORMATION: Form Numbers and Title: PD F 5354--FHA Transaction Request; PD F 5366--FHA New Account Request; PD F 5367--FHA Debenture Transfer Request. OMB Number: 1535-0102. Abstract: The information is used to (1) Establish a book-entry account; (2) change...

  5. 29 CFR 2201.6 - Responses to requests.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... information substantially change the estimated time to process a request, the requester will be notified in... given to be true and correct to the best of his or her knowledge and belief. The certification...

  6. 78 FR 59341 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...: Title, Associated Form and OMB Number: TRICARE Plus Enrollment Application (DD 2853) and TRICARE Plus Disenrollment Request (DD 2854); OMB Control Number 0720-0028. Type of Request: Reinstatement with Change Number...

  7. 20 CFR 422.110 - Individual's request for change in record.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... change in records to any Social Security office, or, if you are outside the U.S., to the Department of... limitations specified in § 422.103(e)(2) for replacement social security number cards representing a change of... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Individual's request for change in record...

  8. 20 CFR 422.110 - Individual's request for change in record.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... change in records to any Social Security office, or, if you are outside the U.S., to the Department of... limitations specified in § 422.103(e)(2) for replacement social security number cards representing a change of... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Individual's request for change in record...

  9. Traffic Aware Strategic Aircrew Requests (TASAR)

    NASA Technical Reports Server (NTRS)

    Ballin, Mark G.; Wing, David J.

    2012-01-01

    Under Instrument Flight Rules, pilots are not permitted to make changes to their approved trajectory without first receiving permission from Air Traffic Control (ATC). Referred to as "user requests," trajectory change requests from aircrews are often denied or deferred by controllers because they have awareness of traffic and airspace constraints not currently available to flight crews. With the introduction of Automatic Dependent Surveillance-Broadcast (ADS-B) and other information services, a rich traffic, weather, and airspace information environment is becoming available on the flight deck. Automation developed by NASA uses this information to aid flight crews in the identification and formulation of optimal conflict-free trajectory requests. The concept of Traffic Aware Strategic Aircrew Requests (TASAR) combines ADS-B and airborne automation to enable user-optimal in-flight trajectory replanning and to increase the likelihood of ATC approval for the resulting trajectory change request. TASAR may improve flight efficiency or other user-desired attributes of the flight while not impacting and potentially benefiting the air traffic controller. This paper describes the TASAR concept of operations, its enabling automation technology which is currently under development, and NASA s plans for concept assessment and maturation.

  10. 78 FR 72687 - Agency Information Collection Activities: Reinstatement, Without Change; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Information Collection Activities: Reinstatement, Without Change; Comment Request ACTION: 30-Day Notice of Information Collection for Review; Form No. I- 333, Obligor Change of Address; OMB Control No. 1653-0042. The... appropriate automated, electronic, mechanical, or other technological collection techniques or other forms of...

  11. Three children with autism spectrum disorder learn to perform a three-step communication sequence using an iPad®-based speech-generating device.

    PubMed

    Waddington, Hannah; Sigafoos, Jeff; Lancioni, Giulio E; O'Reilly, Mark F; van der Meer, Larah; Carnett, Amarie; Stevens, Michelle; Roche, Laura; Hodis, Flaviu; Green, Vanessa A; Sutherland, Dean; Lang, Russell; Marschik, Peter B

    2014-12-01

    Many children with autism spectrum disorder (ASD) have limited or absent speech and might therefore benefit from learning to use a speech-generating device (SGD). The purpose of this study was to evaluate a procedure aimed at teaching three children with ASD to use an iPad(®)-based SGD to make a general request for access to toys, then make a specific request for one of two toys, and then communicate a thank-you response after receiving the requested toy. A multiple-baseline across participants design was used to determine whether systematic instruction involving least-to-most-prompting, time delay, error correction, and reinforcement was effective in teaching the three children to engage in this requesting and social communication sequence. Generalization and follow-up probes were conducted for two of the three participants. With intervention, all three children showed improvement in performing the communication sequence. This improvement was maintained with an unfamiliar communication partner and during the follow-up sessions. With systematic instruction, children with ASD and severe communication impairment can learn to use an iPad-based SGD to complete multi-step communication sequences that involve requesting and social communication functions. Copyright © 2014 ISDN. Published by Elsevier Ltd. All rights reserved.

  12. Joint Intelligence Operations Center (JIOC) Baseline Business Process Model & Capabilities Evaluation Methodology

    DTIC Science & Technology

    2012-03-01

    Targeting Review Board OPLAN Operations Plan OPORD Operations Order OPSIT Operational Situation OSINT Open Source Intelligence OV...Analysis Evaluate FLTREPs MISREPs Unit Assign Assets Feedback Asset Shortfalls Multi-Int Collection Political & Embasy Law Enforcement HUMINT OSINT ...Embassy Information OSINT Manage Theater HUMINT Law Enforcement Collection Sort Requests Platform Information Agency Information M-I Collect

  13. A Preliminary Analysis of Teaching Improvisation with the Picture Exchange Communication System to Children with Autism

    ERIC Educational Resources Information Center

    Marckel, Julie M.; Neef, Nancy A.; Ferreri, Summer J.

    2006-01-01

    Two young boys with autism who used the picture exchange communication system were taught to solve problems (improvise) by using descriptors (functions, colors, and shapes) to request desired items for which specific pictures were unavailable. The results of a multiple baseline across descriptors showed that training increased the number of…

  14. 76 FR 77538 - Family and Youth Services Bureau; Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ...) evaluation design, which will involve baseline surveys and two follow-up surveys. This will allow short- and... descriptive analysis of how States designed and implemented PREP programs. The study will use multiple methods... ``Design Survey'', will focus on how states designed programs, and the second round of interviews, known as...

  15. 78 FR 64598 - Bank Enterprise Award (BEA) Program; Programmatic and Administrative Aspects; Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... an audit opinion a key indicator of the financial health of an Applicant. As stated in Section VII... the time of application if the Applicant received a going concern opinion on its most recent audit... would inform prospective Applicants that a going concern audit opinion during the Baseline Period or the...

  16. 76 FR 70209 - Proposed Information Collection Request; Notice of New Requirements and Procedures for Grant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Procedures for Grant Payment Request Submission. OMB Control Number: XXXX-XXXX. Type of Request: New... Administrations (OAs).\\1\\ DOT is updating systems that support grant payments and there will be changes to the way... requesting payment electronically through the National Highway Traffic Safety Administration's Grant Tracking...

  17. 20 CFR 418.2255 - What kind of evidence of a major life-changing event will you need to support your request for us...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-changing event will you need to support your request for us to use a more recent tax year? 418.2255 Section... Adjustments to Medicare Prescription Drug Coverage Premiums Determinations Using A More Recent Tax Year's... need to support your request for us to use a more recent tax year? We will follow the rules in § 418...

  18. 20 CFR 418.2255 - What kind of evidence of a major life-changing event will you need to support your request for us...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-changing event will you need to support your request for us to use a more recent tax year? 418.2255 Section... Adjustments to Medicare Prescription Drug Coverage Premiums Determinations Using A More Recent Tax Year's... need to support your request for us to use a more recent tax year? We will follow the rules in § 418...

  19. 20 CFR 418.2255 - What kind of evidence of a major life-changing event will you need to support your request for us...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-changing event will you need to support your request for us to use a more recent tax year? 418.2255 Section... Adjustments to Medicare Prescription Drug Coverage Premiums Determinations Using A More Recent Tax Year's... need to support your request for us to use a more recent tax year? We will follow the rules in § 418...

  20. Patient-centeredness and quality management in Dutch diabetes care organizations after a 1-year intervention.

    PubMed

    Campmans-Kuijpers, Marjo Je; Lemmens, Lidwien C; Baan, Caroline A; Rutten, Guy Ehm

    2016-01-01

    More focus on patient-centeredness in care for patients with type 2 diabetes requests increasing attention to diabetes quality management processes on patient-centeredness by managers in primary care groups and outpatient clinics. Although patient-centered care is ultimately determined by the quality of interactions between patients and clinicians at the practice level, it should be facilitated at organizational level too. This nationwide study aimed to assess the state of diabetes quality management on patient-centeredness at organizational level and its possibilities to improve after a tailored intervention. This before-after study compares the quality management on patient-centeredness within Dutch diabetes care groups and outpatient clinics before and after a 1-year stepwise intervention. At baseline, managers of 51 diabetes primary care groups and 28 outpatient diabetes clinics completed a questionnaire about the organization's quality management program. Patient-centeredness (0%-100%) was operationalized in six subdomains: facilitating self-management support, individualized care plan support, patients' access to medical files, patient education policy, safeguarding patients' interests, and formal patient involvement. The intervention consisted of feedback and benchmark and if requested a telephone call and/or a consultancy visit. After 1 year, the managers completed the questionnaire again. The 1-year changes were examined by dependent (non) parametric tests. Care groups improved significantly on patient-centeredness (from 47.1% to 53.3%; P =0.002), and on its subdomains "access to medical files" (from 42.0% to 49.4%), and "safeguarding patients' interests" (from 58.1% to 66.2%). Outpatient clinics, which scored higher at baseline (66.7%) than care groups, did not improve on patient-centeredness (65.6%: P =0.54) or its subdomains. "Formal patient involvement" remained low in both care groups (23.2%) and outpatient clinics (33.9%). After a simple intervention, care groups significantly improved their quality management on patient-centeredness, but outpatient clinics did not. Interventions to improve quality management on patient-centeredness in diabetes care organizations should differ between primary and secondary care.

  1. 18 CFR 281.211 - Filing and documentation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... belief. (2) Local distribution companies. Each request for classification of essential agricultural...) Subsequent request. (i) For 1979, changes in priority 2 entitlements for essential agricultural use... that there has been a change in essential agricultural requirements. (Natural Gas Policy Act of 1978...

  2. WIPP Magnesium Oxide (MgO) - Planned Change Request

    EPA Pesticide Factsheets

    On April 10, 2006, the DOE submitted a planned change request pertaining to the amount of MgO emplaced in the WIPP repository. MgO is an engineered barrier that DOE included as part of the original WIPP Certification Decision.

  3. Videotaped Self-Modeling as a Technique for Training Preschoolers with Autism in Social-Communicative Functioning.

    ERIC Educational Resources Information Center

    Neisworth, John T.; Wert, Barbara Yingling

    This report discusses findings of a study that investigated the effectiveness of video self-modeling (VSM) for increasing request communication of children with autism. A single subject design using multiple baselines across subjects was used. Four participants (ages 4-6) with autism were taped in the home setting for the purpose of creating VSM…

  4. Disaster Down East: Using Participatory Action Research to Explore Intimate Partner Violence in Eastern North Carolina

    ERIC Educational Resources Information Center

    Frasier, Pamela York; Belton, Leigh; Hooten, Elizabeth; Campbell, Marci Kramish; DeVellis, Brenda; Benedict, Salli; Carrillo, Carla; Gonzalez, Pam; Kelsey, Kristine; Meier, Andrea

    2004-01-01

    In the aftermath of Hurricane Floyd in 1999, a Community Advisory Committee requested assistance from its university partners (University of North Carolina) to address stress and increased risk for intimate partner violence (IPV). Collected from 12 study work sites, baseline data indicated that IPV rates were higher among blue-collar women in…

  5. Letter from Galo Jackson, USEPA to Prashant Gupta, Honeywell International, Inc. Subject: Leaching to Groundwater OU3 (Uplands) Baseline Human Health Risk Assessment

    EPA Pesticide Factsheets

    May 27, 2011 letter in response to a request for a status letter for the LCP Chemicals Superfund site and interest in selling Parcel B05308053001 and Tract 4 of Parcel B007800000001 in Brunswick, Georgia. Region ID: 04 DocID: 10748549, DocDate: 05-27-2011

  6. The Picture Exchange Communication System: Effects on Manding and Speech Development for School-Aged Children with Autism

    ERIC Educational Resources Information Center

    Tincani, Matt; Crozier, Shannon; Alazett, Shannon

    2006-01-01

    We examined the effects of the Picture Exchange Communication System (PECS; Frost & Bondy, 2002) on the manding (requesting) and speech development of school-aged children with autism. In study 1, two participants, Damian and Bob, were taught PECS within a delayed multiple baseline design. Both participants demonstrated increased levels of manding…

  7. The Impact of the Picture Exchange Communication System on Requesting and Speech Development in Preschoolers with Autism Spectrum Disorders and Similar Characteristics

    ERIC Educational Resources Information Center

    Ganz, Jennifer B.; Simpson, Richard L.; Corbin-Newsome, Jawanda

    2008-01-01

    By definition children with autism spectrum disorders (ASD) experience difficulty understanding and using language. Accordingly, visual and picture-based strategies such as the Picture Exchange Communication System (PECS) show promise in ameliorating speech and language deficits. This study reports the results of a multiple baseline across…

  8. 76 FR 31358 - Information Collection Request Sent to the Office of Management and Budget (OMB) for Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... Baseline Questionnaire for CLGs 250 .59 148 Annual Achievements Report for CLGs 900 2.20 1,980 State Inventory Maintenance 26,904 .46 12,376 State Review and Compliance Task Tracking 25,370 .17 4,313 State... regulations at 43 CFR part 12. This information collection also produces performance data that we use to...

  9. 76 FR 45799 - Agency Information Collection Activities; Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... the 2005 survey so that the results from it can be used as a baseline for a time-series analysis.\\1... 15 minutes to complete the pretest, the same time as that needed for the actual survey. The revised estimate takes further into account the presumed added time required to respond to questions unique to the...

  10. Promoting Healthy Choices in Non-Chain Restaurants: Effects of a Simple Cue to Customers

    PubMed Central

    Nothwehr, Faryle K.; Snetselaar, Linda; Dawson, Jeffrey; Schultz, Ulrike

    2014-01-01

    This study tested a novel intervention to influence restaurant customer ordering behavior, with measurements at baseline and 3, 6, and 12 months postintervention in four owner-operated restaurants in the Midwest. A sample of 141 to 370 customers was surveyed at each time point. The response rate was 70% to 84% with 59% women, 98% White, and a mean age of 53 years. Table signs listed changes customers might consider, for example, asking for meat broiled instead of fried or requesting smaller portions. Customer surveys measured program reach and effectiveness. Owner interviews measured perceptions of program burden and customer response. Order slips were analyzed for evidence of changes in ordering. Window signs were noticed by 40%, 48%, and 45% of customers at each follow-up, respectively. Table signs were noticed by 67%, 71%, and 69% of customers, respectively. Of those, 34% at each time point stated that the signs influenced their order. Examples of how orders were influenced were elicited. Order slip data not only did not show significant changes but was also found to be an inadequate measure for the intervention. Owners reported no concerns or complaints. This intervention resulted in small but positive behavior changes among a portion of customers. Because of its simplicity and acceptability, it has great potential for dissemination. PMID:23048009

  11. Promoting healthy choices in non-chain restaurants: effects of a simple cue to customers.

    PubMed

    Nothwehr, Faryle K; Snetselaar, Linda; Dawson, Jeffrey; Schultz, Ulrike

    2013-01-01

    This study tested a novel intervention to influence restaurant customer ordering behavior, with measurements at baseline and 3, 6, and 12 months postintervention in four owner-operated restaurants in the Midwest. A sample of 141 to 370 customers was surveyed at each time point. The response rate was 70% to 84% with 59% women, 98% White, and a mean age of 53 years. Table signs listed changes customers might consider, for example, asking for meat broiled instead of fried or requesting smaller portions. Customer surveys measured program reach and effectiveness. Owner interviews measured perceptions of program burden and customer response. Order slips were analyzed for evidence of changes in ordering. Window signs were noticed by 40%, 48%, and 45% of customers at each follow-up, respectively. Table signs were noticed by 67%, 71%, and 69% of customers, respectively. Of those, 34% at each time point stated that the signs influenced their order. Examples of how orders were influenced were elicited. Order slip data not only did not show significant changes but was also found to be an inadequate measure for the intervention. Owners reported no concerns or complaints. This intervention resulted in small but positive behavior changes among a portion of customers. Because of its simplicity and acceptability, it has great potential for dissemination.

  12. 76 FR 64377 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Alien's Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... Collection; Comments Requested: Alien's Change of Address Forms: 33/BIA Board of Immigration Appeals and 33... approved collection. (2) Title of the Form/Collection: Alien's Change of Address Forms: 33/BIA Board of... determine where to send notices of the next administrative action or of any decisions in an alien's case. (5...

  13. 76 FR 80403 - Agency Information Collection Activities; Proposed collection; Comments Request: Alien's Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... collection; Comments Request: Alien's Change of Address Form: 33/BIA Board of Immigration Appeal; 33/IC... Collection. (2) Title of the Form/Collection: Alien's Change of Address Forms 33/BIA Board of Immigration... send notices of the next administrative action or of any decisions in an alien's case. (5) An estimate...

  14. 29 CFR 4903.19 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... change in circumstances such as catastrophic illness, divorce, death, or disability? 4903.19 Section 4903... debtor request a special review based on a change in circumstances such as catastrophic illness, divorce... not limited to, catastrophic illness, divorce, death, or disability. (b) Inability to pay. For...

  15. 29 CFR 4903.19 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... change in circumstances such as catastrophic illness, divorce, death, or disability? 4903.19 Section 4903... debtor request a special review based on a change in circumstances such as catastrophic illness, divorce... not limited to, catastrophic illness, divorce, death, or disability. (b) Inability to pay. For...

  16. 29 CFR 4903.19 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... change in circumstances such as catastrophic illness, divorce, death, or disability? 4903.19 Section 4903... debtor request a special review based on a change in circumstances such as catastrophic illness, divorce... not limited to, catastrophic illness, divorce, death, or disability. (b) Inability to pay. For...

  17. 29 CFR 4903.19 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... change in circumstances such as catastrophic illness, divorce, death, or disability? 4903.19 Section 4903... debtor request a special review based on a change in circumstances such as catastrophic illness, divorce... not limited to, catastrophic illness, divorce, death, or disability. (b) Inability to pay. For...

  18. 77 FR 30325 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ...] Agency Information Collection Activities: Proposed Collection; Comments Requested: Notification of Change... through the use of appropriate automated, electronic, mechanical, or other technological collection... currently approved collection. (2) Title of the Form/Collection: Notification of Change of Mailing or...

  19. 78 FR 45275 - Agency Information Collection Activities; Proposed collection; Comments Requested: Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ...] Agency Information Collection Activities; Proposed collection; Comments Requested: Notification of Change... technological collection techniques or other forms of information technology, e.g., permitting electronic... currently approved collection. (2) Title of the Form/Collection: Notification of Change of Mailing or...

  20. Implementing a reward and reminder underage drinking prevention program in convenience stores near Southern California American Indian reservations

    PubMed Central

    Moore, Roland S.; Roberts, Jennifer; McGaffigan, Richard; Calac, Daniel; Grube, Joel W.; Gilder, David A.; Ehlers, Cindy L.

    2012-01-01

    Background Underage drinking is associated with a number of social and public health consequences. Preventing access to alcohol is one approach to reducing underage drinking. Objectives This study assesses the efficacy of a culturally tailored “reward and reminder” program aimed at reducing convenience store alcohol sales to youth living on or near nine American Indian reservations. Methods First, tribal council proclamations were sought to support underage drinking prevention, including reward and reminder efforts. Then, decoys (volunteers over 21 years of age but judged to look younger) attempted to purchase alcohol without identification. Clerks who asked for identification were given “rewards” (gift cards and congratulatory letters), whereas clerks who did not were given “reminders” of the law regarding sales to minors. Following an initial baseline of 12 purchase attempts, three repeated reward and reminder visits were made to 13 convenience stores selling alcohol within ten miles of the reservations (n=51 total attempts). Results Five of nine tribal councils passed resolutions in support of the program. The baseline sales rate without requesting ID was 33%. Similarly, 38% of stores in the first reward and reminder visit round failed to request identification. However, in the following two reward and reminder rounds, 0% of the stores failed to request identification. Conclusions These results indicate that environmental community-level underage drinking prevention strategies to reduce alcohol sales near rural reservations are feasible and can be effective. Scientific Significance Environmental prevention strategies within reservation communities support integrated supply and demand reduction models for reducing underage drinking. PMID:22931080

  1. 78 FR 21617 - Notice of Proposed Information Collection: Comment Request; Multifamily Project Construction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... Information Collection: Comment Request; Multifamily Project Construction Contract, Building Loan Agreement, and Construction Change Request AGENCY: Office of the Assistant Secretary for Housing, HUD. ACTION.... This Notice also lists the following information: Title of Proposal: Multifamily Project Construction...

  2. 75 FR 76951 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... harassment/refusal to board, safety or performance concerns, 15 minutes each; observer provider change in... of contracts with observers or vessels, change in ownership information, and reports of harassment of...

  3. 78 FR 77667 - Proposed Agency Information Collection Extension With Changes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... with changes, under the provisions of the Paperwork Reduction Act of 1995, for the Electricity and.../electricity/ . SUPPLEMENTARY INFORMATION: This information collection request contains: (1) OMB No.: 1905-0129; (2) Information Collection Request Title: Electricity and Renewables Power Surveys; (3) Type of...

  4. 77 FR 44270 - Agency Information Collection Activities; Proposed Collection; Comments Requested: Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ...] Agency Information Collection Activities; Proposed Collection; Comments Requested: Notification of Change... automated, electronic, mechanical, or other technological collection techniques or other forms of...: Notification of Change of Mailing or Premise Address. (3) Agency form number, if any, and the applicable...

  5. 78 FR 59722 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ...] Agency Information Collection Activities: Proposed Collection; Comments Requested; Notification of Change... automated, electronic, mechanical, or other technological collection techniques or other forms of...: Notification of Change of Mailing or Premise Address. (3) Agency form number, if any, and the applicable...

  6. Patient-initiated electronic health record amendment requests

    PubMed Central

    Hanauer, David A; Preib, Rebecca; Zheng, Kai; Choi, Sung W

    2014-01-01

    Background and objective Providing patients access to their medical records offers many potential benefits including identification and correction of errors. The process by which patients ask for changes to be made to their records is called an ‘amendment request’. Little is known about the nature of such amendment requests and whether they result in modifications to the chart. Methods We conducted a qualitative content analysis of all patient-initiated amendment requests that our institution received over a 7-year period. Recurring themes were identified along three analytic dimensions: (1) clinical/documentation area, (2) patient motivation for making the request, and (3) outcome of the request. Results The dataset consisted of 818 distinct requests submitted by 181 patients. The majority of these requests (n=636, 77.8%) were made to rectify incorrect information and 49.7% of all requests were ultimately approved. In 6.6% of the requests, patients wanted valid information removed from their record, 27.8% of which were approved. Among all of the patients requesting a copy of their chart, only a very small percentage (approximately 0.2%) submitted an amendment request. Conclusions The low number of amendment requests may be due to inadequate awareness by patients about how to make changes to their records. To make this approach effective, it will be important to inform patients of their right to view and amend records and about the process for doing so. Increasing patient access to medical records could encourage patient participation in improving the accuracy of medical records; however, caution should be used. PMID:24863430

  7. Climate Hazard Assessment for Stakeholder Adaptation Planning in New York City

    NASA Technical Reports Server (NTRS)

    Horton, Radley M.; Gornitz, Vivien; Bader, Daniel A.; Ruane, Alex C.; Goldberg, Richard; Rosenzweig, Cynthia

    2011-01-01

    This paper describes a time-sensitive approach to climate change projections, developed as part of New York City's climate change adaptation process, that has provided decision support to stakeholders from 40 agencies, regional planning associations, and private companies. The approach optimizes production of projections given constraints faced by decision makers as they incorporate climate change into long-term planning and policy. New York City stakeholders, who are well-versed in risk management, helped pre-select the climate variables most likely to impact urban infrastructure, and requested a projection range rather than a single 'most likely' outcome. The climate projections approach is transferable to other regions and consistent with broader efforts to provide climate services, including impact, vulnerability, and adaptation information. The approach uses 16 Global Climate Models (GCMs) and three emissions scenarios to calculate monthly change factors based on 30-year average future time slices relative to a 30- year model baseline. Projecting these model mean changes onto observed station data for New York City yields dramatic changes in the frequency of extreme events such as coastal flooding and dangerous heat events. Based on these methods, the current 1-in-10 year coastal flood is projected to occur more than once every 3 years by the end of the century, and heat events are projected to approximately triple in frequency. These frequency changes are of sufficient magnitude to merit consideration in long-term adaptation planning, even though the precise changes in extreme event frequency are highly uncertain

  8. 78 FR 59671 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NESHAP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... anticipated to change over the next three years; and (2) the growth rate for the respondents is very low... is that all comments received will be included in the public docket without change including any... 40 CFR part 63, subpart A, and any changes, or additions, to the Provisions specified at 40 CFR part...

  9. 75 FR 45600 - Information Collection; Customer Data Worksheet Request for Service Center Information Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection; Customer Data Worksheet Request for Service Center Information Management System (SCIMS) Record Changes AGENCY: Farm Service... Customer Data Worksheet Request for Service Center Information Management System (SCIMS) that contains the...

  10. Analysis of Operational Hazards and Safety Requirements for Traffic Aware Strategic Aircrew Requests (TASAR)

    NASA Technical Reports Server (NTRS)

    Koczo, Stefan, Jr.

    2013-01-01

    Safety analyses of the Traffic Aware Strategic Aircrew Requests (TASAR) Electronic Flight Bag (EFB) application are provided to establish its Failure Effects Classification which affects certification and operational approval requirements. TASAR was developed by NASA Langley Research Center to offer flight path improvement opportunities to the pilot during flight for operational benefits (e.g., reduced fuel, flight time). TASAR, using own-ship and network-enabled information concerning the flight and its environment, including weather and Air Traffic Control (ATC) system constraints, provides recommended improvements to the flight trajectory that the pilot can choose to request via Change Requests to ATC for revised clearance. This study reviews the Change Request process of requesting updates to the current clearance, examines the intended function of TASAR, and utilizes two safety assessment methods to establish the Failure Effects Classification of TASAR. Considerable attention has been given in this report to the identification of operational hazards potentially associated with TASAR.

  11. 77 FR 25692 - Marine Mammals; File No. 16479

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ...], 300 Maalaea Road, Suite 211, Wailuku, HI 96793, has requested a change in Principal Investigator to..., environmental variables, vessel behavior, whale abundance, and individual sex and age classes. Up to 567... activities. Under the pending permit application, The Pacific Whale Foundation is requesting a change in...

  12. Interlibrary loan in US and Canadian health sciences libraries 2005: update on journal article use.

    PubMed

    Lacroix, Eve-Marie; Collins, Maria Elizabeth

    2007-04-01

    The authors analyzed 2.48 million interlibrary loan (ILL) requests entered in the National Library of Medicine's (NLM's) DOCLINE system from 3,234 US and Canadian medical libraries during fiscal year (FY) 2005 to study their distribution and nature and the journals in which requested articles were published. Data from DOCLINE and NLM's indexing system and online catalog were used to analyze all DOCLINE ILL transactions acted on from October 2004 to September 2005. The authors compared results from this analysis to previous data collected in FY 1992. Overall ILL volume in the United States and Canada is at about the same level as FY 1992 despite marked growth in online searching, knowledge discovery tools, and journals available online. Over 21,000 unique journal titles and 1.4 million unique articles were used to fill 2.2 million ILL requests in FY 2005. Over 1 million of the articles were requested only once by any network library. Fifty-two percent (11,022) of journals had 5 or fewer requests for articles from all the years of a journal by all libraries in the network. Fifty-two percent of the articles requested were published within the most recent 5 years. The overall ILL profile in the libraries studied has changed little since FY 1992, notable given other changes in publishing. Small changes, however, may reveal developing trends. Total ILL traffic has been declining in recent years following a peak in 2002, and fewer of the articles requested were published in the most recent five years compared to requests from 1992.

  13. Knowledge Assessment of the Dental Community in Texas on the Role of Human Papilloma Virus in Oropharyngeal Cancer.

    PubMed

    Rowan, Stephanie D; Hu, Shirley L; Brotzman, Jacob S; Redding, Spencer W; Rankin, K Vendrell; Vigneswaran, Nadarajah

    2015-08-01

    The epidemiology of oral cancer is changing. From 1988 to 2004, there has been a dramatic increase in Human Papilloma virus (HPV) positive oropharyngeal squamous cell carcinoma (OPC) in the U.S. At the same time there have been decreasing rates of OPC associated with the traditional risk factors of smoking and alcohol consumption. The epidemiology of oral cancer is changing. As the epidemiology changes, it is important that the dental community recognize these factors. The goal of this study was to assess the baseline level of knowledge about HPV and OPC within the Texas dental community. Practicing dentists and dental hygienists from Texas dental professional networks and dental students from the three Texas schools of dentistry were recruited to participate in the study. Participants were requested to access and complete a 7-item online survey. To ensure anonymity, a third party practice facilitator or department administrator disseminated the survey link to participants. Of the 457 surveys completed, 100% of respondents reported conducting oral soft tissue examinations at least annually. However, only 73% included the oropharynx in their exam. Less than 50% of dental professionals selected the correct location of the greatest increase in oral cancer incidence during the last 10 years. Less than 30% of each of the groups answered correctly in indicating the age group with the most rapidly increasing incidence of oral cancer. Approximately 40% of all groups indicated that a biopsy from the posterior oropharynx should be tested for HPV. Survey results across Texas dentists, dental hygienists, and Texas dental students demonstrated a lack of knowledge of the changing profile of oral cancer regarding HPV-associated OPC. This aim of this initial phase was to determine the baseline level of knowledge surrounding the risks associated with oropharyngeal cancer in the survey population. Our goal is to utilize these findings to develop educational interventions that will be disseminated throughout the dental community in Texas to improve diagnosis of these devastating cancers.

  14. 77 FR 31832 - Proposed Information Collection; Comment Request; Procedures for Considering Requests and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... Section 328 of the United States-Colombia Trade Promotion Agreement Implementation Act (the ``Act... of the United States- Colombia Trade Promotion Agreement (the ``Agreement''). This safeguard... directly competitive article; and (5) all data available to the requester showing changes in productivity...

  15. Enhanced Oceanic Operations Human-In-The-Loop In-Trail Procedure Validation Simulation Study

    NASA Technical Reports Server (NTRS)

    Murdoch, Jennifer L.; Bussink, Frank J. L.; Chamberlain, James P.; Chartrand, Ryan C.; Palmer, Michael T.; Palmer, Susan O.

    2008-01-01

    The Enhanced Oceanic Operations Human-In-The-Loop In-Trail Procedure (ITP) Validation Simulation Study investigated the viability of an ITP designed to enable oceanic flight level changes that would not otherwise be possible. Twelve commercial airline pilots with current oceanic experience flew a series of simulated scenarios involving either standard or ITP flight level change maneuvers and provided subjective workload ratings, assessments of ITP validity and acceptability, and objective performance measures associated with the appropriate selection, request, and execution of ITP flight level change maneuvers. In the majority of scenarios, subject pilots correctly assessed the traffic situation, selected an appropriate response (i.e., either a standard flight level change request, an ITP request, or no request), and executed their selected flight level change procedure, if any, without error. Workload ratings for ITP maneuvers were acceptable and not substantially higher than for standard flight level change maneuvers, and, for the majority of scenarios and subject pilots, subjective acceptability ratings and comments for ITP were generally high and positive. Qualitatively, the ITP was found to be valid and acceptable. However, the error rates for ITP maneuvers were higher than for standard flight level changes, and these errors may have design implications for both the ITP and the study's prototype traffic display. These errors and their implications are discussed.

  16. Determining Mobility Support Advisory Squadron Effectiveness in Support of Building Partner Capacity

    DTIC Science & Technology

    2012-06-15

    Pamela Bennet Bardot, USAF Expeditionary Center Librarian - Extraordinaire for graciously entertaining my numerous requests for information and helping... standardized , realistic set of performance criteria can ensure standardization between the MSAS and give AMC a baseline from which to inspect compliance...continue to mature. They include: • Lacking a universally recognized and utilized lexicon. In reference to working with PNs, common , interchangeably

  17. 78 FR 78694 - Airworthiness Directives; Airbus Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... all Airbus Model A330-200 and -300 series airplanes, and Model A340-200 and -300 series airplanes. AD..., and corrective actions if needed. This new AD expands the applicability, reduces the compliance time... the comment received. Request To Change Compliance Time US Airways requested that we change the...

  18. 75 FR 39619 - Proposed Information Collection (Dependent's Request for Change of Program or Place of Training...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits... the notice. This notice solicits comments on the information needed to request a change of education... to Nancy J. Kessinger, Veterans Benefits Administration (20M35), Department of Veterans Affairs, 810...

  19. 78 FR 65764 - Information Collection Proposed Renewal Without Change; Comment Request; Anti-Money Laundering...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... Renewal Without Change; Comment Request; Anti-Money Laundering Programs; Due Diligence Programs for... policies, procedures, and controls reasonably designed to detect and report money laundering through... Enforcement Network, P.O. Box 39, Vienna, VA 22183, Attention: Comments on Anti-Money Laundering Program and...

  20. 75 FR 16899 - Public Notice for a Change in Use of Aeronautical Property at Houlton International Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Public Notice for a Change in Use of Aeronautical Property at Houlton International Airport, Houlton, ME AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Request for Public Comments. SUMMARY: The FAA is requesting public comment on the...

  1. 76 FR 2757 - Proposed Information Collection (Application for Change of Permanent Plan (Medical); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... (Application for Change of Permanent Plan (Medical); Comment Request AGENCY: Veterans Benefits Administration... collection of certain information by the agency. Under the Paperwork Reduction Act (PRA) of 1995, Federal agencies are required to publish notice in the Federal Register concerning each proposed collection of...

  2. 78 FR 33452 - International Product Change-Global Reseller Expedited Package Contracts 2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... POSTAL SERVICE International Product Change--Global Reseller Expedited Package Contracts 2 AGENCY... request with the Postal Regulatory Commission to add Global Reseller Expedited Package Contracts 2 to the... Regulatory Commission, a request to add Global Reseller Expedited Package Contracts 2 (GREP Contracts 2) to...

  3. 44 CFR 72.5 - Exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Requests for map changes based on mapping or study analysis errors; (b) Requests for map changes based on... and hydraulic studies conducted by Federal, State, or local agencies to replace approximate studies... information meant to improve upon that shown on the flood map or within the flood study will be exempt from...

  4. 44 CFR 72.5 - Exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Requests for map changes based on mapping or study analysis errors; (b) Requests for map changes based on... and hydraulic studies conducted by Federal, State, or local agencies to replace approximate studies... information meant to improve upon that shown on the flood map or within the flood study will be exempt from...

  5. 75 FR 8188 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ...-9, and RP 2008-52, RP 2009-XX; Changes in Methods of Accounting. Description: The information... taxpayer properly is requesting to change its method of accounting and the terms and conditions of the... approved collection. Title: REG-141402-02 Limitation on Use of the Nonaccrual-Experience Method of...

  6. 78 FR 63521 - Product Change-Parcel Select & Parcel Return Service Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... POSTAL SERVICE Product Change--Parcel Select & Parcel Return Service Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY: The Postal Service gives notice of filing a request... Request of the United States Postal Service to Add Parcel Select & Parcel Return Service Contract 5 to...

  7. 78 FR 59671 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NESHAP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... in the public docket without change including any personal information provided, unless the comment...: 144 (total). Frequency of response: Initially, quarterly, and semiannually. Total estimated burden: 23... year), includes $800 annualized capital or operation & maintenance costs. Changes in the Estimates...

  8. 76 FR 33326 - Agency Information Collection Activities, Submission for OMB Review; Comment Request; Severe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... request for comments; extension, without change, of a currently approved information collection; FEMA Form...) Appeals. Type of information collection: Extension, without change, of a currently approved information... owners with the ability to appeal an increase in their flood insurance premium rate if they refuse an...

  9. Patients' experiences of an open access follow up arrangement in managing inflammatory bowel disease

    PubMed Central

    Rogers, A; Kennedy, A; Nelson, E; Robinson, A

    2004-01-01

    Background: Improving access is a key policy issue in improving quality of care and extending patient choice and participation. People's experience of changing from fixed outpatient appointments to more flexible direct access arrangements for chronic disease has been underexplored. Objectives: To examine patients' views on using an open system of access compared with fixed outpatient appointments as part of a guided self-management intervention for inflammatory bowel disease (IBD). Design: Embedded qualitative study undertaken alongside a randomised controlled trial. Semi-structured interviews were undertaken to obtain an in depth understanding of patients' experience of the change in access arrangements. Participants: A purposive sample (n = 30) was drawn from the intervention group (n = 700) according to a range of responses to the trial baseline and follow up quantitative measures. Results: 28 interviews were included in the analysis. Compared with the previous system of fixed appointments, preference for the new open access system was based on enhanced personal control in contacting services and the view that it fitted better with everyday routine management and the requirement for urgent medical contact when symptoms fail to respond to medication. Preference for retaining fixed appointments was based on a sense of security from gaining access which did not require the individual to initiate the request for medical help. Conclusions: Open access may fit better with patients' self-management of their condition and everyday routines, roles and responsibilities. Ensuring that outpatient organisational arrangements and personnel are responsive to patient initiated requests for appointments is likely to impact on the acceptability of this type of access arrangement. Some people may continue to prefer the fixed appointment system which should be retained if patient choice is to be respected. PMID:15465941

  10. Does counsellor's attitude influence change in a request for a caesarean in women with fear of birth?

    PubMed

    Halvorsen, Lotta; Nerum, Hilde; Sørlie, Tore; Oian, Pål

    2010-02-01

    the attitudes of two counsellors towards women requesting a caesarean section due to fear of birth were identified. One emphasised the ability to overcome any emotional obstacle to vaginal birth ('coping attitude'), and the other emphasised that the ultimate choice of mode of birth was the womans' ('autonomy attitude'). Two research questions were asked: (1) What are the predictors of change in a wish for a caesarean and of vaginal birth in women with fear of birth? (2) Does a change from an 'autonomy attitude' to a 'coping attitude' increase the number of women who change their request for a caesarean and who give birth vaginally? the study population consisted of two samples of pregnant women with fear of birth and concurrent request for a caesarean, referred for crisis-oriented counselling at the antenatal clinic, University Hospital of North Norway between 2000-2002 (n=86) and 2004-2006 (n=107). Data were gathered from referral letters, counseling and antenatal, intra- and postpartum records. a coping attitude of the counsellor was positively associated with change in the request for a caesarean and with vaginal birth. A change from an autonomy attitude to a coping attitude was associated with a significant increase in the percentage of women who changed their desire for a caesarean from 77 to 93, and who had a vaginal birth from 42 to 81. a coping attitude was strongly associated with change in the desire for a caesarean and giving birth vaginally. A coping attitude can be learned through critical reflection and awareness of the counsellor's attitude, with measurable clinical results. Copyright 2008 Elsevier Ltd. All rights reserved.

  11. 20 CFR 418.2255 - What kind of evidence of a major life-changing event will you need to support your request for us...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-changing event will you need to support your request for us to use a more recent tax year? 418.2255 Section 418.2255 Employees' Benefits SOCIAL SECURITY ADMINISTRATION MEDICARE SUBSIDIES Income-Related Monthly... Modified Adjusted Gross Income § 418.2255 What kind of evidence of a major life-changing event will you...

  12. Prognostic Value of Adipokines in Predicting Cardiovascular Outcome: Explaining the Obesity Paradox.

    PubMed

    Wolk, Robert; Bertolet, Marnie; Singh, Prachi; Brooks, Maria M; Pratley, Richard E; Frye, Robert L; Mooradian, Arshag D; Rutter, Martin K; Calvin, Andrew D; Chaitman, Bernard R; Somers, Virend K

    2016-07-01

    To evaluate the cardiovascular (CV) prognostic value of adipokines in a large prospective cohort of patients participating in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial. The effects of the adipokine levels at baseline and change from baseline on the composite outcome (CV death, myocardial infarction, and stroke) were analyzed using unadjusted and fully adjusted Cox models in 2330 patients with type 2 diabetes and coronary artery disease who had participated in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial (from January 1, 2001, through December 1, 2008). In a fully adjusted model, baseline leptin and change from baseline leptin were protective for CV events, whereas baseline adiponectin, baseline tumor necrosis factor α (TNF-α), change from baseline TNF-α, baseline C-reactive protein (CRP), and change from baseline CRP were harmful. The effect of baseline leptin on CV events depended on the body mass index (BMI), such that the hazard ratios (HRs) varied between 0.6 and 1.4 across the BMI quintiles (interaction P=.03). The same was true for baseline adiponectin (HR varied from 0.7 to 1.7; interaction P=.01), change from baseline monocyte chemoattractant protein-1 (HR varied from 0.8 to 1.8; interaction P=.03), change from baseline TNF-α (HR varied from 0.9 to 1.4; interaction P=.02), and change from baseline IL-6 (HR varied from 0.7 to 1.8; interaction P=.005). Adipokines are independent predictors of CV events in patients with type 2 diabetes and coronary artery disease. The association between the specific adipokines and CV outcome varies depending on BMI. This reflects the complex pathophysiology of CV disease in obesity and may help explain the "obesity paradox." clinicaltrials.gov Identifier: NCT00006305. Copyright © 2016 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  13. 78 FR 58350 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Operations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... for OMB Review; Comment Request; Operations Under Water ACTION: Notice. SUMMARY: The Department of... collection request (ICR) titled, ``Operations Under Water,'' to the Office of Management and Budget (OMB) for review and approval for continued use, without change, in accordance with the Paperwork Reduction Act...

  14. 76 FR 52956 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... (HPBS) Transmission File Layouts for HPBS Work Measures OMB No.: 0970-0230 Description: There is no... provide us less precise information on States' performance. The Transmission File Layouts form provides... requested to transmit similar files. We are not requesting any changes to the Transmission File Layouts form...

  15. 76 FR 18301 - Proposed Collection; Comment Request for HCTC Program Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... requests of; changes to their account information, waivers from the Federal requirement that mandates all... on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of... INFORMATION CONTACT: Requests for additional information or copies of the form and instructions should be...

  16. 75 FR 53983 - Proposed Information Collection Request of the ETA-5130 Benefit Appeals Report; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-02

    ... of the ETA-5130 Benefit Appeals Report; Comment Request on Extension Without Change (OMB Control [email protected] . SUPPLEMENTARY INFORMATION: I. Background The ETA-5130, Benefit Appeals Report, contains... Training Administration is soliciting comments concerning the proposed extension collection of the ETA-5130...

  17. 77 FR 59013 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Consumer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    ... for OMB Review; Comment Request; Consumer Price Index Housing Survey ACTION: Notice. SUMMARY: The... request (ICR) titled, ``Consumer Price Index Housing Survey,'' to the Office of Management and Budget (OMB...)(D). SUPPLEMENTARY INFORMATION: The Consumer Price Index (CPI) is a measure of the average change...

  18. 75 FR 72841 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Job Corps...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... for OMB Review; Comment Request; Job Corps Health Questionnaire ACTION: Notice. SUMMARY: The...) sponsored information collection request (ICR) titled, ``Job Corps Health Questionnaire,'' to the Office of... without change of a currently approved collection. Title of Collection: Job Corps Health Questionnaire...

  19. 44 CFR 72.3 - Fee schedule.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... structural measures; (8) Requests for LOMRs and PMRs based on as-built information for projects for which...) Requests for CLOMRs based on projects involving levees, berms, or other structural measures. (d) If a... PROCESSING MAP CHANGES § 72.3 Fee schedule. (a) For requests for CLOMRs, LOMRs, and PMRs based on structural...

  20. 77 FR 50146 - Agency Information Collection Activities: Extension, With Change, of an Existing Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... Request ACTION: 60-day notice of information collection; 10-002; Electronic Funds Transfer Waiver Request... appropriate automated, electronic, mechanical, or other technological collection techniques or other forms of.... (2) Title of the Form/Collection: Electronic Funds Transfer Waiver Request. (3) Agency form number...

  1. Interlibrary loan in US and Canadian health sciences libraries 2005: update on journal article use

    PubMed Central

    Lacroix, Eve-Marie; Collins, Maria Elizabeth

    2007-01-01

    Purpose: The authors analyzed 2.48 million interlibrary loan (ILL) requests entered in the National Library of Medicine's (NLM's) DOCLINE system from 3,234 US and Canadian medical libraries during fiscal year (FY) 2005 to study their distribution and nature and the journals in which requested articles were published. Methods: Data from DOCLINE and NLM's indexing system and online catalog were used to analyze all DOCLINE ILL transactions acted on from October 2004 to September 2005. The authors compared results from this analysis to previous data collected in FY 1992. Results: Overall ILL volume in the United States and Canada is at about the same level as FY 1992 despite marked growth in online searching, knowledge discovery tools, and journals available online. Over 21,000 unique journal titles and 1.4 million unique articles were used to fill 2.2 million ILL requests in FY 2005. Over 1 million of the articles were requested only once by any network library. Fifty-two percent (11,022) of journals had 5 or fewer requests for articles from all the years of a journal by all libraries in the network. Fifty-two percent of the articles requested were published within the most recent 5 years. Conclusion: The overall ILL profile in the libraries studied has changed little since FY 1992, notable given other changes in publishing. Small changes, however, may reveal developing trends. Total ILL traffic has been declining in recent years following a peak in 2002, and fewer of the articles requested were published in the most recent five years compared to requests from 1992. PMID:17443252

  2. 48 CFR 252.243-7002 - Requests for equitable adjustment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the change, and shall not include any costs that already have been reimbursed or that have been separately claimed. All indirect costs included in the request shall be properly allocable to the change in... supporting data are accurate and complete to the best of my knowledge and belief. (Official's Name) (Title...

  3. 76 FR 19515 - Public Notice for a Change in Use of Aeronautical Property at Bradford Regional Airport (BFD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... Aeronautical Property at Bradford Regional Airport (BFD), Bradford, PA AGENCY: Federal Aviation Administration... Administration is requesting public comment on the Bradford Regional Airport Authority's request to change 35.46... Bradford Regional Airport (BFD) in Lafayette Township, McKean County, PA. The property is currently...

  4. 78 FR 11619 - Greenhouse Gas Reporting Rule: Revision to Best Available Monitoring Method Request Submission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... is (202) 566-1742. FOR FURTHER INFORMATION CONTACT: Carole Cook, Climate Change Division, Office of... Rule must submit requests for use of best available monitoring methods to the Administrator. This proposed revision does not change any other requirements for owners or operators as outlined in the best...

  5. 77 FR 38731 - Defense Federal Acquisition Regulation Supplement: Updates to Wide Area WorkFlow (DFARS Case 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... generating invoices and receiving reports. TEDS is an accepted system for processing payment requests for... follows: A. Summary of Significant Changes Changes to the proposed rule to clarify language were made at... receive payment requests and receiving reports and clarify language and to clarify instructions for...

  6. 78 FR 29433 - Proposed Information Collection (Dependent's Request for Change of Program or Place of Training...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits... request a change of education program or place of training. DATES: Written comments and recommendations on...) at www.Regulations.gov or to Nancy J. Kessinger, Veterans Benefits Administration (20M35), Department...

  7. 78 FR 47426 - Virgil C. Summer Nuclear Station, Units 2 and 3; South Carolina Electric and Gas; Change to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Additional Electrical Penetration Assemblies AGENCY: Nuclear Regulatory Commission. ACTION: Exemption and... requested adding four electrical penetration assemblies to the containment vessel and shield building in... assemblies to containment and the shield building. As part of this request, the licensee needed to change...

  8. Requests for new oral antibiotic prescriptions in children within 2 days: a Norwegian population-based study.

    PubMed

    Bergene, E H; Nordeng, H; Rø, T B; Steinsbekk, A

    2018-05-09

    Children commonly refuse to take antibiotics, which may induce parents to request new antibiotic prescriptions with different pharmaceutical characteristics. To investigate prescription changes for children 0-12 years receiving oral liquid or solid antibiotic formulations and to explore the relationships between prescription changes and characteristics related to the child, prescriber and antibiotic. A population-based registry study based on data from the Norwegian Prescription Database (NorPD) from 2004 to 2016. Antibiotic prescription changes were defined as the dispensing of subsequent antibiotics with different pharmaceutical characteristics to the same child within 2 days after initial prescriptions. Data were analysed using multivariable logistic regression and generalized estimating equations. Requests for new prescriptions followed 3.0% of 2 691 483 initial antibiotic prescriptions for children. Young children who received solid formulations (10.9%) and certain poor-tasting antibiotics (8.6%) had the highest proportions of new prescriptions. Penicillin V was most commonly changed, while macrolides/lincosamides dominated subsequent prescriptions. In order of magnitude, the characteristics associated with requests for new prescriptions were the children's ages, poor taste and concentration of liquids, size and shape of solids, prescribers born in recent decades, and girl patients. Reimbursed prescriptions and scored solids were associated with fewer requests. While only 3% of the antibiotic prescriptions were changed, the preference of broad-spectrum over narrow-spectrum antibiotics for young children in this study mirrors international prescription patterns. Avoiding the costs of children's refusal and consequent changes may thus be a motivation for choosing more preferred antibiotics.

  9. Instruction and Pragmatic Change during Study Abroad Email Communication

    ERIC Educational Resources Information Center

    Alcón-Soler, Eva

    2015-01-01

    The study deals with the effect of instruction and study abroad (SA) on pragmatic knowledge. More specifically, the focus is on gains in explicit knowledge of request mitigators, and whether learners draw on this knowledge when they perform email requests. Email requests produced by 60 Spanish students staying abroad (30 treatment/30 control…

  10. 5 CFR 1650.17 - Changes and cancellation of a withdrawal request.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... processes withdrawal requests each business day and those that are entered into the record keeping system by 12:00 noon eastern time will ordinarily be processed that night; those entered after 12:00 noon eastern time will be processed the next business day. Consequently, a cancellation request must be...

  11. 77 FR 12444 - Airworthiness Directives; General Electric Company (GE) Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... support the NPRM as written. Request To Correct Part Number Commenters GE and Delta Airlines (Delta... packing configuration either on-wing or in the shop and to determine if further actions are necessary. We.... Request To Modify Compliance Time Commenters GE and Delta requested that we change the compliance time of...

  12. 75 FR 27557 - Agency Information Collection Activities: Final Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... many FTEs were supported or created for this deal; and d. Changed the amount of financeable local costs... transaction requests submitted to the Export Import Bank under its long term guarantee and direct loan... transaction requests submitted to the Export Import Bank under its long term guarantee and direct loan...

  13. 76 FR 27665 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Consumer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-12

    ... INFORMATION: The Consumer Price Index (CPI) is a measure of the average change over time in the prices paid by... for OMB Review; Comment Request; Consumer Price Index Commodities and Services Survey ACTION: Notice...) sponsored information collection request (ICR) titled, ``Consumer Price Index Commodities and Services...

  14. 77 FR 60742 - Proposed Collection; Comment Request for TD 9178

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... receipt of a request or demand for disclosure of IRS records or information. The purpose of the final... make requests or demands for disclosure. Current Actions: There is no change in the paperwork burden... forms of information technology; and (e) estimates of capital or start-up costs and costs of operation...

  15. Re-Assessing Green Building Performance: A Post Occupancy Evaluation of 22 GSA Buildings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fowler, Kimberly M.; Rauch, Emily M.; Henderson, Jordan W.

    2010-06-01

    2nd report on the performance of GSA's sustainably designed buildings. The purpose of this study was to provide an overview of measured whole building performance as it compares to GSA and industry baselines. The PNNL research team found the data analysis illuminated strengths and weaknesses of individual buildings as well as the portfolio of buildings. This section includes summary data, observations that cross multiple performance metrics, discussion of lessons learned from this research, and opportunities for future research. The summary of annual data for each of the performance metrics is provided in Table 25. The data represent 1 year ofmore » measurements and are not associated with any specific design features or strategies. Where available, multiple years of data were examined and there were minimal significant differences between the years. Individually focused post occupancy evaluation (POEs) would allow for more detailed analysis of the buildings. Examining building performance over multiple years could potentially offer a useful diagnostic tool for identifying building operations that are in need of operational changes. Investigating what the connection is between the building performance and the design intent would offer potential design guidance and possible insight into building operation strategies. The 'aggregate operating cost' metric used in this study represents the costs that were available for developing a comparative industry baseline for office buildings. The costs include water utilities, energy utilities, general maintenance, grounds maintenance, waste and recycling, and janitorial costs. Three of the buildings that cost more than the baseline in Figure 45 have higher maintenance costs than the baseline, and one has higher energy costs. Given the volume of data collected and analyzed for this study, the inevitable request is for a simple answer with respect to sustainably designed building performance. As previously stated, compiling the individual building values into single metrics is not statistically valid given the small number of buildings, but it has been done to provide a cursory view of this portfolio of sustainably designed buildings. For all metrics except recycling cost per rentable square foot and CBE survey response rate, the averaged building performance was better than the baseline for the GSA buildings in this study.« less

  16. Teaching Young People Who Are Blind and Have Autism to Make Requests Using a Variation on the Picture Exchange Communication System with Tactile Symbols: A Preliminary Investigation

    ERIC Educational Resources Information Center

    Lund, Shelley K.; Troha, Jeanette M.

    2008-01-01

    This study used a single-subject multiple baseline across participants design to evaluate the effectiveness of a modified picture exchange communication system (PECS) teaching protocol with tactile symbols. Three students (two male, one female) aged 12-17 years who had autism and were blind participated in the study. The instructional program…

  17. Staying Connected: A Feasibility Study Linking American Indian and Alaska Native Trauma Survivors to their Tribal Communities

    PubMed Central

    Tsosie, Ursula; Nannauck, Sweetwater; Buchwald, Dedra; Russo, Joan; Geiss Trusz, Sarah; Foy, Hugh; Zatzick, Douglas

    2013-01-01

    The objective of this investigation was to assess the feasibility of a culturally tailored care management intervention for physically injured American Indian/Alaska Native (AI/AN) patients. The intervention was initiated at a Level I trauma center and aimed to link AI/AN patients to their distant tribal communities. Thirty AI/AN patients were randomized to the intervention or to usual care. Assessments at baseline, 3 months, and 6 months included self-reported lifetime cumulative trauma burden, Native healing requests, and symptoms of posttraumatic stress, depression, and alcohol use. Generalized estimating equations ascertained differences between groups over time. Ninety-four percent of eligible patients participated; follow-up at 3 and 6 months was 83%. Participants had high numbers of lifetime traumas (mean = 5.1, standard deviation = 2.6). No differences between the intervention and control groups were observed in posttraumatic stress symptoms, depression symptoms, or alcohol use at baseline or follow-up time points. Among intervention patients, 60% either requested or participated in traditional Native healing practices and 75% reported that the intervention was helpful. This effectiveness trial demonstrated the feasibility of recruiting and randomizing injured AI/AN patients. Future efforts could integrate evidence-based interventions and traditional Native healing into stepped collaborative care treatment programs. PMID:22168295

  18. Changed nursing scheduling for improved safety culture and working conditions - patients' and nurses' perspectives.

    PubMed

    Kullberg, Anna; Bergenmar, Mia; Sharp, Lena

    2016-05-01

    To evaluate fixed scheduling compared with self-scheduling for nursing staff in oncological inpatient care with regard to patient and staff outcomes. Various scheduling models have been tested to attract and retain nursing staff. Little is known about how these schedules affect staff and patients. Fixed scheduling and self-scheduling have been studied to a small extent, solely from a staff perspective. We implemented fixed scheduling on two of four oncological inpatient wards. Two wards kept self-scheduling. Through a quasi-experimental design, baseline and follow-up measurements were collected among staff and patients. The Safety Attitudes Questionnaire was used among staff, as well as study-specific questions for patients and staff. Fixed scheduling was associated with less overtime and fewer possibilities to change shifts. Self-scheduling was associated with more requests from management for short notice shift changes. The type of scheduling did not affect patient-reported outcomes. Fixed scheduling should be considered in order to lower overtime. Further research is necessary and should explore patient outcomes to a greater extent. Scheduling is a core task for nurse managers. Our study suggests fixed scheduling as a strategy for managers to improve the effective use of resources and safety. © 2016 John Wiley & Sons Ltd.

  19. Protocol for population testing of an Internet-based Personalised Decision Support system for colorectal cancer screening

    PubMed Central

    2010-01-01

    Background Australia has a comparatively high incidence of colorectal (bowel) cancer; however, population screening uptake using faecal occult blood test (FOBT) remains low. This study will determine the impact on screening participation of a novel, Internet-based Personalised Decision Support (PDS) package. The PDS is designed to measure attitudes and cognitive concerns and provide people with individually tailored information, in real time, that will assist them with making a decision to screen. The hypothesis is that exposure to (tailored) PDS will result in greater participation in screening than participation following exposure to non-tailored PDS or resulting from the current non-tailored, paper-based approach. Methods/design A randomised parallel trial comprising three arms will be conducted. Men and women aged 50-74 years (N = 3240) will be recruited. They must have access to the Internet; have not had an FOBT within the previous 12 months, or sigmoidoscopy or colonoscopy within the previous 5 years; have had no clinical diagnosis of bowel cancer. Groups 1 and 2 (PDS arms) will access a website and complete a baseline survey measuring decision-to-screen stage, attitudes and cognitive concerns and will receive immediate feedback; Group 1 will receive information 'tailored' to their responses in the baseline survey and group 2 will received 'non-tailored' bowel cancer information. Respondents in both groups will subsequently receive an FOBT kit. Group 3 (usual practice arm) will complete a paper-based version of the baseline survey and respondents will subsequently receive 'non-tailored' paper-based bowel cancer information with accompanying FOBT kit. Following despatch of FOBTs, all respondents will be requested to complete an endpoint survey. Main outcome measures are (1) completion of FOBT and (2) change in decision-to-screen stage. Secondary outcomes include satisfaction with decision and change in attitudinal scores from baseline to endpoint. Analyses will be performed using Chi-square tests, analysis of variance and log binomial generalized linear models as appropriate. Discussion It is necessary to restrict participants to Internet users to provide an appropriately controlled evaluation of PDS. Once efficacy of the approach has been established, it will be important to evaluate effectiveness in the wider at-risk population, and to identify barriers to its implementation in those settings. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12610000095066 PMID:20843369

  20. 78 FR 49551 - Vogtle Electric Generating Station, Units 3 and 4; Southern Nuclear Operating Company; Change to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... design and layout of the turbine building. As part of this request, the licensee needed to change the... information related to the design and layout of the Turbine Building detailed in the amendment request. These... Structures and Layout AGENCY: Nuclear Regulatory Commission. ACTION: Exemption and combined license amendment...

  1. 77 FR 2573 - International Product Change-Global Plus 1C and 2C Negotiated Service Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... POSTAL SERVICE International Product Change--Global Plus 1C and 2C Negotiated Service Agreements... a request with the Postal Regulatory Commission to add Global Plus 1C and 2C Negotiated Service... with the Postal Regulatory Commission, Requests of United States Postal Service to Add Global Plus 1C...

  2. 78 FR 72079 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... of the true value of the audit sample to the compliance authority (state, local or EPA Regional... AASP. The AASP would report the true value of the audit sample to the compliance authority (state..., validating, disturbing and reporting the audit results. Changes in the Estimates: There are no changes in the...

  3. 76 FR 55458 - Agency Information Collection Activities: Notice of request for approval of a new information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... substantial changes to our business including funding, the workforce, State and National policy dynamics and the systems used to deliver products and services to the public. What has not changed is the... collection. SUMMARY: The FHWA invites public comments about our intention to request the Office of Management...

  4. 76 FR 20451 - Proposed Collection; Comment Request; Renewal Without Change of the Registration of Money...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Request; Renewal Without Change of the Registration of Money Services Business, FinCEN Form 107 AGENCY... Money Services Business, FinCEN Form 107. The form will be used by currency dealers or exchangers; check cashers; issuers of traveler's checks, money orders or stored value; sellers of traveler's checks, money...

  5. 43 CFR 3106.3 - Fees.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of this chapter. Each request for a transfer to an heir or devisee, request for a change of name, or notification of a corporate merger under § 3106.8, must include payment of the processing fee for name changes, corporate mergers or transfers to heir/devisee found in the fee schedule in § 3000.12 of this chapter. Each...

  6. 43 CFR 3106.3 - Fees.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of this chapter. Each request for a transfer to an heir or devisee, request for a change of name, or notification of a corporate merger under § 3106.8, must include payment of the processing fee for name changes, corporate mergers or transfers to heir/devisee found in the fee schedule in § 3000.12 of this chapter. Each...

  7. 43 CFR 3106.3 - Fees.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of this chapter. Each request for a transfer to an heir or devisee, request for a change of name, or notification of a corporate merger under § 3106.8, must include payment of the processing fee for name changes, corporate mergers or transfers to heir/devisee found in the fee schedule in § 3000.12 of this chapter. Each...

  8. 43 CFR 3106.3 - Fees.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of this chapter. Each request for a transfer to an heir or devisee, request for a change of name, or notification of a corporate merger under § 3106.8, must include payment of the processing fee for name changes, corporate mergers or transfers to heir/devisee found in the fee schedule in § 3000.12 of this chapter. Each...

  9. 76 FR 9615 - Agency Forms Submitted for OMB Review, Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... Regulatory Affairs (OIRA), Office of Management and Budget (OMB) to request an extension without change of a... the Social Security Act, states may enter into ``buy-in agreements'' with the Secretary of Health and... voluntary. One response is received from each respondent. The RRB proposes no changes to Form RL-380-F...

  10. System of and method for transparent management of data objects in containers across distributed heterogenous resources

    DOEpatents

    Moore, Reagan W.; Rajasekar, Arcot; Wan, Michael Y.

    2004-01-13

    A system of and method for maintaining data objects in containers across a network of distributed heterogeneous resources in a manner which is transparent to a client. A client request pertaining to containers is resolved by querying meta data for the container, processing the request through one or more copies of the container maintained on the system, updating the meta data for the container to reflect any changes made to the container as a result processing the request, and, if a copy of the container has changed, changing the status of the copy to indicate dirty status or synchronizing the copy to one or more other copies that may be present on the system.

  11. System of and method for transparent management of data objects in containers across distributed heterogenous resources

    DOEpatents

    Moore, Reagan W.; Rajasekar, Arcot; Wan, Michael Y.

    2010-09-21

    A system of and method for maintaining data objects in containers across a network of distributed heterogeneous resources in a manner which is transparent to a client. A client request pertaining to containers is resolved by querying meta data for the container, processing the request through one or more copies of the container maintained on the system, updating the meta data for the container to reflect any changes made to the container as a result processing the request, and, if a copy of the container has changed, changing the status of the copy to indicate dirty status or synchronizing the copy to one or more other copies that may be present on the system.

  12. Improvements in Health Behaviors, Eating Self-Efficacy, and Goal-Setting Skills Following Participation in Wellness Coaching.

    PubMed

    Clark, Matthew M; Bradley, Karleah L; Jenkins, Sarah M; Mettler, Emily A; Larson, Brent G; Preston, Heather R; Liesinger, Juliette T; Werneburg, Brooke L; Hagen, Philip T; Harris, Ann M; Riley, Beth A; Olsen, Kerry D; Vickers Douglas, Kristin S

    2016-07-01

    Purpose . This project examined potential changes in health behaviors following wellness coaching. Design . In a single cohort study design, wellness coaching participants were recruited in 2011, data were collected through July 2012, and were analyzed through December 2013. Items in the study questionnaire used requested information about 11 health behaviors, self-efficacy for eating, and goal-setting skills. Setting . Worksite wellness center. Participants . One-hundred employee wellness center members with an average age of 42 years; 90% were female and most were overweight or obese. Intervention . Twelve weeks of in-person, one-on-one wellness coaching. Method . Participants completed study questionnaires when they started wellness coaching (baseline), after 12 weeks of wellness coaching, and at a 3-month follow-up. Results . From baseline to week 12, these 100 wellness coaching participants improved their self-reported health behaviors (11 domains, 0- to 10-point scale) from an average of 6.4 to 7.7 (p < .001), eating self-efficacy from an average of 112 to 142 (on a 0- to 180-point scale; p < .001), and goal-setting skills from an average of 49 to 55 (on a 16- to 80-point scale; p < .001). Conclusion . These results suggest that participants improved their current health behaviors and learned skills for continued healthy living. Future studies that use randomized controlled trials are needed to establish causality for wellness coaching.

  13. Baseline Levels, and Changes Over Time in Body Mass Index and Fasting Insulin, and Their Relationship to Change in Metabolic Trait Clustering

    PubMed Central

    Sullivan, Lisa M.; Fox, Caroline S.; Wilson, Peter W.F.; Nathan, David M.; Vasan, Ramachandran S.; D'Agostino, Ralph B.; Meigs, James B.

    2014-01-01

    Abstract Background: Multiple abnormal metabolic traits are found together or “cluster” within individuals more often than is predicted by chance. The individual and combined role of adiposity and insulin resistance (IR) on metabolic trait clustering is uncertain. We tested the hypothesis that change in trait clustering is a function of both baseline level and change in these measures. Methods: In 2616 nondiabetic Framingham Offspring Study participants, body mass index (BMI) and fasting insulin were related to a within-person 7-year change in a trait score of 0–4 Adult Treatment Panel III metabolic syndrome traits (hypertension, high triglycerides, low high-density lipoprotein cholesterol, hyperglycemia). Results: At baseline assessment, mean trait score was 1.4 traits, and 7-year mean (SEM) change in trait score was +0.25 (0.02) traits, P<0.0001. In models with BMI predictors only, for every quintile difference in baseline BMI, the 7-year trait score increase was 0.14 traits, and for every quintile increase in BMI during 7-year follow-up, the trait score increased by 0.3 traits. Baseline level and change in fasting insulin were similarly related to trait score change. In models adjusted for age–sex–baseline cluster score, 7-year change in trait score was significantly related to both a 1-quintile difference in baseline BMI (0.07 traits) and fasting insulin (0.18 traits), and to both a 1-quintile 7-year increase in BMI (0.21 traits) and fasting insulin (0.18 traits). Conclusions: Change in metabolic trait clustering was significantly associated with baseline levels and changes in both BMI and fasting insulin, highlighting the importance of both obesity and IR in the clustering of metabolic traits. PMID:25007010

  14. 32 CFR 767.8 - Requests for amendments or extensions of active permits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Requests for amendments or extensions of active permits. 767.8 Section 767.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... extensions of active permits. (a) Requests for amendments to active permits (e.g., a change in study design...

  15. 32 CFR 767.8 - Requests for amendments or extensions of active permits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Requests for amendments or extensions of active permits. 767.8 Section 767.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... extensions of active permits. (a) Requests for amendments to active permits (e.g., a change in study design...

  16. 32 CFR 767.8 - Requests for amendments or extensions of active permits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Requests for amendments or extensions of active permits. 767.8 Section 767.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... extensions of active permits. (a) Requests for amendments to active permits (e.g., a change in study design...

  17. 32 CFR 767.8 - Requests for amendments or extensions of active permits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Requests for amendments or extensions of active permits. 767.8 Section 767.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... extensions of active permits. (a) Requests for amendments to active permits (e.g., a change in study design...

  18. 76 FR 33761 - Agency Information Collection Request. 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... behavior change, interaction design, and service innovation to increase the understanding and adoption of Comparative Effectiveness Research (CER) information by physicians and patients. By truly understanding the...

  19. Measuring Historical Coastal Change using GIS and the Change Polygon Approach

    USGS Publications Warehouse

    Smith, M.J.; Cromley, R.G.

    2012-01-01

    This study compares two automated approaches, the transect-from-baseline technique and a new change polygon method, for quantifying historical coastal change over time. The study shows that the transect-from-baseline technique is complicated by choice of a proper baseline as well as generating transects that intersect with each other rather than with the nearest shoreline. The change polygon method captures the full spatial difference between the positions of the two shorelines and average coastal change is the defined as the ratio of the net area divided by the shoreline length. Although then change polygon method is sensitive to the definition and measurement of shoreline length, the results are more invariant to parameter changes than the transect-from-baseline method, suggesting that the change polygon technique may be a more robust coastal change method. ?? 2012 Blackwell Publishing Ltd.

  20. 78 FR 23329 - Notice of Release From Federal Surplus Property and Grant Assurance Obligations at Oroville...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... Airport and serving the interest of civil aviation. The City is also requesting a land-use change for... its sale and a land-use change for approximately 13.62 acres of airport land for long term leasing for... AGENCY: Federal Aviation Administration, DOT. ACTION: Notice of request to release airport land. SUMMARY...

  1. Education Reform: School-Based Management Results in Changes in Instruction and Budgeting. Report to Congressional Requesters.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Health, Education, and Human Services Div.

    This report responds to a request for information on School Based Management (SBM) from Senators Edward M. Kennedy and David Durenberger. It answers the following questions: (1) Under SBM, did administrators and teachers change their schools' instructional programs and budgets and, if so, how? (2) What were key similarities and differences in…

  2. 20 CFR 418.1250 - What evidence will you need to support your request that we use a more recent tax year?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... request that we use a more recent tax year? 418.1250 Section 418.1250 Employees' Benefits SOCIAL SECURITY... determine your income-related monthly adjustment amount, we will ask for evidence of the major life-changing..., additional evidence documenting the major life-changing event(s) will not be needed. ...

  3. 20 CFR 418.1250 - What evidence will you need to support your request that we use a more recent tax year?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... request that we use a more recent tax year? 418.1250 Section 418.1250 Employees' Benefits SOCIAL SECURITY... determine your income-related monthly adjustment amount, we will ask for evidence of the major life-changing..., additional evidence documenting the major life-changing event(s) will not be needed. ...

  4. 75 FR 4080 - Submission for OMB Review; Comment Request; Next Series of Tobacco Use Supplements to the Current...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... request: REINSTATEMENT WITH CHANGE of OMB 0925-0368, Expiration 4/30/2009. Need and Use of Information...; health professional advice to stop smoking; and changes in smoking norms and attitudes. The TUS-CPS will... that need to be provided. A unique feature is the ability to link other social and economic Census...

  5. Preliminary Benefits Assessment of Traffic Aware Strategic Aircrew Requests (TASAR)

    NASA Technical Reports Server (NTRS)

    Henderson, Jeff; Idris, Husni; Wing, David J.

    2012-01-01

    While en route, aircrews submit trajectory change requests to air traffic control (ATC) to better meet their objectives including reduced delays, reduced fuel burn, and passenger comfort. Aircrew requests are currently made with limited to no information on surrounding traffic. Consequently, these requests are uninformed about a key ATC objective, ensuring traffic separation, and therefore less likely to be accepted than requests informed by surrounding traffic and that avoids creating conflicts. This paper studies the benefits of providing aircrews with on-board decision support to generate optimized trajectory requests that are probed and cleared of known separation violations prior to issuing the request to ATC. These informed requests are referred to as traffic aware strategic aircrew requests (TASAR) and leverage traffic surveillance information available through Automatic Dependent Surveillance Broadcast (ADS-B) In capability. Preliminary fast-time simulation results show increased benefits with longer stage lengths since beneficial trajectory changes can be applied over a longer distance. Also, larger benefits were experienced between large hub airports as compared to other airport sizes. On average, an aircraft equipped with TASAR reduced its travel time by about one to four minutes per operation and fuel burn by about 50 to 550 lbs per operation depending on the objective of the aircrew (time, fuel, or weighted combination of time and fuel), class of airspace user, and aircraft type. These preliminary results are based on analysis of approximately one week of traffic in July 2012 and additional analysis is planned on a larger data set to confirm these initial findings.

  6. 77 FR 12448 - Airworthiness Directives; Pratt & Whitney Division Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... Delta Airlines, Inc. requested that we specify replacing affected FMUs with FMU P/N 53U044, or later FAA... actual cost of the AD; not other costs. We did not change the AD. Request To Replace FMUs On-Wing United Parcel Service Co. requested that we include in the AD the option to perform on-wing replacements of...

  7. Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients.

    PubMed

    Denardo, Scott J; Vock, David M; Schmalfuss, Carsten M; Young, Gregory D; Tcheng, James E; O'Connor, Christopher M

    2016-07-01

    Contrast media administered during cardiac catheterization can affect hemodynamic variables. However, little is documented about the effects of contrast on hemodynamics in heart failure patients or the prognostic value of baseline and changes in hemodynamics for predicting subsequent adverse events. In this prospective study of 150 heart failure patients, we measured hemodynamics at baseline and after administration of iodixanol or iopamidol contrast. One-year Kaplan-Meier estimates of adverse event-free survival (death, heart failure hospitalization, and rehospitalization) were generated, grouping patients by baseline measures of pulmonary capillary wedge pressure (PCWP) and cardiac index (CI), and by changes in those measures after contrast administration. We used Cox proportional hazards modeling to assess sequentially adding baseline PCWP and change in CI to 5 validated risk models (Seattle Heart Failure Score, ESCAPE [Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness], CHARM [Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity], CORONA [Controlled Rosuvastatin Multinational Trial in Heart Failure], and MAGGIC [Meta-Analysis Global Group in Chronic Heart Failure]). Median contrast volume was 109 mL. Both contrast media caused similarly small but statistically significant changes in most hemodynamic variables. There were 39 adverse events (26.0%). Adverse event rates increased using the composite metric of baseline PCWP and change in CI (P<0.01); elevated baseline PCWP and decreased CI after contrast correlated with the poorest prognosis. Adding both baseline PCWP and change in CI to the 5 risk models universally improved their predictive value (P≤0.02). In heart failure patients, the administration of contrast causes small but significant changes in hemodynamics. Calculating baseline PCWP with change in CI after contrast predicts adverse events and increases the predictive value of existing models. Patients with elevated baseline PCWP and decreased CI after contrast merit greatest concern. © 2016 American Heart Association, Inc.

  8. Pain and fear avoidance partially mediate change in muscle strength during resistance exercise in women with fibromyalgia.

    PubMed

    Larsson, Anette; Palstam, Annie; Löfgren, Monika; Ernberg, Malin; Bjersing, Jan; Bileviciute-Ljungar, Indre; Gerdle, Björn; Kosek, Eva; Mannerkorpi, Kaisa

    2017-11-21

    Resistance exercise results in health benefits in fibromyalgia. The aim of this study was to determine the factors that mediate change in muscle strength in women with fibromyalgia as a result of resistance exercise. Sixty-seven women with fibromyalgia (age range 25-64 years) were included. Tests of muscle strength and questionnaires related to pain, fear avoidance and physical activity were carried out. Multivariable stepwise regression was used to analyse explanatory factors for change and predictors for final values of knee-extension force, elbow-flexion force and hand-grip force. Change in knee-extension force was explained by fear avoidance beliefs about physical activity at baseline, together with change in pain intensity, knee-extension force at baseline, age and body mass index (BMI) (R2=0.40, p = 0.013). Change in elbow-flexion force was explained by pain intensity at baseline, together with baseline fear avoidance beliefs about physical activity, BMI and elbow-flexion force at baseline (R2 = 0.32, p = 0.043). Change in hand-grip force was explained by hand-grip force at baseline, change in pain intensity and baseline fear avoidance (R2 = 0.37, p = 0.009). Final muscle strength was predicted by the same variables as change, except pain. Pain and fear avoidance are important factors to consider in rehabilitation using resistance exercise for women with fibromyalgia.

  9. Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users.

    PubMed

    Beale, Camilla; Broyd, Samantha J; Chye, Yann; Suo, Chao; Schira, Mark; Galettis, Peter; Martin, Jennifer H; Yücel, Murat; Solowij, Nadia

    2018-01-01

    Introduction: Chronic cannabis use is associated with neuroanatomical alterations in the hippocampus. While adverse impacts of cannabis use are generally attributed to Δ 9 -tetrahydrocannabinol, emerging naturalistic evidence suggests cannabidiol (CBD) is neuroprotective and may ameliorate brain harms associated with cannabis use, including protection from hippocampal volume loss. This study examined whether prolonged administration of CBD to regular cannabis users within the community could reverse or reduce the characteristic hippocampal harms associated with chronic cannabis use. Materials and Methods: Eighteen regular cannabis users participated in an ∼10-week open-label pragmatic trial involving daily oral administration of 200 mg CBD, with no change to their ongoing cannabis use requested. Participants were assessed at baseline and post-CBD treatment using structural magnetic resonance imaging. Automated longitudinal hippocampal segmentation was performed to assess volumetric change over the whole hippocampus and within 12 subfields. Results: No change was observed in left or right hippocampus as a whole. However, left subicular complex (parasubiculum, presubiculum, and subiculum) volume significantly increased from baseline to post-treatment ( p =0.017 uncorrected) by 1.58% (Cohen's d =0.63; 2.83% in parasubiculum). Heavy cannabis users demonstrated marked growth in the left subicular complex, predominantly within the presubiculum, and right cornu ammonis (CA)1 compared to lighter users. Associations between greater right subicular complex and total hippocampal volume and higher plasma CBD concentration were evident, particularly in heavy users. Conclusions: Our findings suggest a restorative effect of CBD on the subicular and CA1 subfields in current cannabis users, especially those with greater lifetime exposure to cannabis. While replication is required in a larger, placebo-controlled trial, these findings support a protective role of CBD against brain structural harms conferred by chronic cannabis use. Furthermore, these outcomes suggest that CBD may be a useful adjunct in treatments for cannabis dependence and may be therapeutic for a range of clinical disorders characterized by hippocampal pathology (e.g., schizophrenia, Alzheimer's disease, and major depressive disorder).

  10. Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users

    PubMed Central

    Beale, Camilla; Broyd, Samantha J.; Chye, Yann; Suo, Chao; Schira, Mark; Galettis, Peter; Martin, Jennifer H.; Yücel, Murat; Solowij, Nadia

    2018-01-01

    Abstract Introduction: Chronic cannabis use is associated with neuroanatomical alterations in the hippocampus. While adverse impacts of cannabis use are generally attributed to Δ9-tetrahydrocannabinol, emerging naturalistic evidence suggests cannabidiol (CBD) is neuroprotective and may ameliorate brain harms associated with cannabis use, including protection from hippocampal volume loss. This study examined whether prolonged administration of CBD to regular cannabis users within the community could reverse or reduce the characteristic hippocampal harms associated with chronic cannabis use. Materials and Methods: Eighteen regular cannabis users participated in an ∼10-week open-label pragmatic trial involving daily oral administration of 200 mg CBD, with no change to their ongoing cannabis use requested. Participants were assessed at baseline and post-CBD treatment using structural magnetic resonance imaging. Automated longitudinal hippocampal segmentation was performed to assess volumetric change over the whole hippocampus and within 12 subfields. Results: No change was observed in left or right hippocampus as a whole. However, left subicular complex (parasubiculum, presubiculum, and subiculum) volume significantly increased from baseline to post-treatment (p=0.017 uncorrected) by 1.58% (Cohen's d=0.63; 2.83% in parasubiculum). Heavy cannabis users demonstrated marked growth in the left subicular complex, predominantly within the presubiculum, and right cornu ammonis (CA)1 compared to lighter users. Associations between greater right subicular complex and total hippocampal volume and higher plasma CBD concentration were evident, particularly in heavy users. Conclusions: Our findings suggest a restorative effect of CBD on the subicular and CA1 subfields in current cannabis users, especially those with greater lifetime exposure to cannabis. While replication is required in a larger, placebo-controlled trial, these findings support a protective role of CBD against brain structural harms conferred by chronic cannabis use. Furthermore, these outcomes suggest that CBD may be a useful adjunct in treatments for cannabis dependence and may be therapeutic for a range of clinical disorders characterized by hippocampal pathology (e.g., schizophrenia, Alzheimer's disease, and major depressive disorder). PMID:29682609

  11. Patient-centeredness and quality management in Dutch diabetes care organizations after a 1-year intervention

    PubMed Central

    Campmans-Kuijpers, Marjo JE; Lemmens, Lidwien C; Baan, Caroline A; Rutten, Guy EHM

    2016-01-01

    Background More focus on patient-centeredness in care for patients with type 2 diabetes requests increasing attention to diabetes quality management processes on patient-centeredness by managers in primary care groups and outpatient clinics. Although patient-centered care is ultimately determined by the quality of interactions between patients and clinicians at the practice level, it should be facilitated at organizational level too. This nationwide study aimed to assess the state of diabetes quality management on patient-centeredness at organizational level and its possibilities to improve after a tailored intervention. Methods This before–after study compares the quality management on patient-centeredness within Dutch diabetes care groups and outpatient clinics before and after a 1-year stepwise intervention. At baseline, managers of 51 diabetes primary care groups and 28 outpatient diabetes clinics completed a questionnaire about the organization’s quality management program. Patient-centeredness (0%–100%) was operationalized in six subdomains: facilitating self-management support, individualized care plan support, patients’ access to medical files, patient education policy, safeguarding patients’ interests, and formal patient involvement. The intervention consisted of feedback and benchmark and if requested a telephone call and/or a consultancy visit. After 1 year, the managers completed the questionnaire again. The 1-year changes were examined by dependent (non) parametric tests. Results Care groups improved significantly on patient-centeredness (from 47.1% to 53.3%; P=0.002), and on its subdomains “access to medical files” (from 42.0% to 49.4%), and “safeguarding patients’ interests” (from 58.1% to 66.2%). Outpatient clinics, which scored higher at baseline (66.7%) than care groups, did not improve on patient-centeredness (65.6%: P=0.54) or its subdomains. “Formal patient involvement” remained low in both care groups (23.2%) and outpatient clinics (33.9%). Conclusion After a simple intervention, care groups significantly improved their quality management on patient-centeredness, but outpatient clinics did not. Interventions to improve quality management on patient-centeredness in diabetes care organizations should differ between primary and secondary care. PMID:27784994

  12. Effect of local wound infiltration with ketamine versus dexmedetomidine on postoperative pain and stress after abdominal hysterectomy, a randomized trial.

    PubMed

    Mohamed, S A; Sayed, D M; El Sherif, F A; Abd El-Rahman, A M

    2018-05-01

    Postoperative pain and stress elicit hormonal changes. We aimed at comparing the effects of wound infiltration with ketamine versus dexmedetomidine on postoperative pain and stress response. This double-blinded study included ninety patients scheduled for total abdominal hysterectomy and were randomly assigned into three groups to receive local wound infiltration with 40 mL of 0.25% bupivacaine (group C), plus 2 mg/kg ketamine (group K) or 2 μg/kg dexmedetomidine (group D). Primary outcome was postoperative morphine consumption; secondary outcomes included first request of analgesia, VAS scores at rest and movement (VAS-R/M) and side effects. Serum cortisol, prolactin and glucose levels at baseline, pre-infiltration, 6 and 24 h postoperatively were measured. Rescue analgesia was less in K (6.80 ± 3.19 mg) and D (8.39 ± 3.86 mg) compared to C (13.33 ± 4.01 mg) (p < 0.05). First request of analgesia was delayed in K (7.60 ± 4.16 h) and D (6.00 ± 3.73 h) compared to C (4.20 ± 1.13 h) (p < 0.05). Both VAS and R/M were significantly lower in K (all over 24 h) and D (for 8 and 4 h, respectively) compared to C. Stress markers were significantly lower in K and D compared to C at 6 and 24 h, and in K compared to D at 24 h (p < 0.05). Local wound infiltration with ketamine or dexmedetomidine added to bupivacaine had an opioid-sparing effect, delayed first request of rescue analgesia, and attenuated postoperative stress response, especially with ketamine in patients underwent total abdominal hysterectomy. © 2018 European Pain Federation - EFIC®.

  13. Change Analysis in Structural Laser Scanning Point Clouds: The Baseline Method

    PubMed Central

    Shen, Yueqian; Lindenbergh, Roderik; Wang, Jinhu

    2016-01-01

    A method is introduced for detecting changes from point clouds that avoids registration. For many applications, changes are detected between two scans of the same scene obtained at different times. Traditionally, these scans are aligned to a common coordinate system having the disadvantage that this registration step introduces additional errors. In addition, registration requires stable targets or features. To avoid these issues, we propose a change detection method based on so-called baselines. Baselines connect feature points within one scan. To analyze changes, baselines connecting corresponding points in two scans are compared. As feature points either targets or virtual points corresponding to some reconstructable feature in the scene are used. The new method is implemented on two scans sampling a masonry laboratory building before and after seismic testing, that resulted in damages in the order of several centimeters. The centres of the bricks of the laboratory building are automatically extracted to serve as virtual points. Baselines connecting virtual points and/or target points are extracted and compared with respect to a suitable structural coordinate system. Changes detected from the baseline analysis are compared to a traditional cloud to cloud change analysis demonstrating the potential of the new method for structural analysis. PMID:28029121

  14. Change Analysis in Structural Laser Scanning Point Clouds: The Baseline Method.

    PubMed

    Shen, Yueqian; Lindenbergh, Roderik; Wang, Jinhu

    2016-12-24

    A method is introduced for detecting changes from point clouds that avoids registration. For many applications, changes are detected between two scans of the same scene obtained at different times. Traditionally, these scans are aligned to a common coordinate system having the disadvantage that this registration step introduces additional errors. In addition, registration requires stable targets or features. To avoid these issues, we propose a change detection method based on so-called baselines. Baselines connect feature points within one scan. To analyze changes, baselines connecting corresponding points in two scans are compared. As feature points either targets or virtual points corresponding to some reconstructable feature in the scene are used. The new method is implemented on two scans sampling a masonry laboratory building before and after seismic testing, that resulted in damages in the order of several centimeters. The centres of the bricks of the laboratory building are automatically extracted to serve as virtual points. Baselines connecting virtual points and/or target points are extracted and compared with respect to a suitable structural coordinate system. Changes detected from the baseline analysis are compared to a traditional cloud to cloud change analysis demonstrating the potential of the new method for structural analysis.

  15. Evaluation of software maintain ability with open EHR - a comparison of architectures.

    PubMed

    Atalag, Koray; Yang, Hong Yul; Tempero, Ewan; Warren, James R

    2014-11-01

    To assess whether it is easier to maintain a clinical information system developed using open EHR model driven development versus mainstream methods. A new open source application (GastrOS) has been developed following open EHR's multi-level modelling approach using .Net/C# based on the same requirements of an existing clinically used application developed using Microsoft Visual Basic and Access database. Almost all the domain knowledge was embedded into the software code and data model in the latter. The same domain knowledge has been expressed as a set of open EHR Archetypes in GastrOS. We then introduced eight real-world change requests that had accumulated during live clinical usage, and implemented these in both systems while measuring time for various development tasks and change in software size for each change request. Overall it took half the time to implement changes in GastrOS. However it was the more difficult application to modify for one change request, suggesting the nature of change is also important. It was not possible to implement changes by modelling only. Comparison of relative measures of time and software size change within each application highlights how architectural differences affected maintain ability across change requests. The use of open EHR model driven development can result in better software maintain ability. The degree to which open EHR affects software maintain ability depends on the extent and nature of domain knowledge involved in changes. Although we used relative measures for time and software size, confounding factors could not be totally excluded as a controlled study design was not feasible. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  16. 77 FR 11383 - Change of Address and Electronic Submission of FOIA Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ...The Federal Retirement Thrift Investment Board (Agency) is amending its regulations to reflect its new office address and to permit Freedom of Information Act (FOIA) requests via electronic mail and facsimile.

  17. 75 FR 63476 - Agency Information Collection Activities; Request for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ..., Investigator, Division of Marketing Practices, Bureau of Consumer Protection, Federal Trade Commission, Room H... new warranties and changes to existing warranties comply with the Rule--requires a mix of legal...

  18. 78 FR 76986 - Version 5 Critical Infrastructure Protection Reliability Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-20

    ...].'' The sentence as revised would thus read, ``NERC requests that the CIP version 5 Standards become... 16 is changed to ``[ninth].'' The sentence as revised would thus read, ``NERC requests that the CIP...

  19. Evaluating Alzheimer's disease biomarkers as mediators of age-related cognitive decline.

    PubMed

    Hohman, Timothy J; Tommet, Doug; Marks, Shawn; Contreras, Joey; Jones, Rich; Mungas, Dan

    2017-10-01

    Age-related changes in cognition are partially mediated by the presence of neuropathology and neurodegeneration. This manuscript evaluates the degree to which biomarkers of Alzheimer's disease, (AD) neuropathology and longitudinal changes in brain structure, account for age-related differences in cognition. Data from the AD Neuroimaging Initiative (n = 1012) were analyzed, including individuals with normal cognition and mild cognitive impairment. Parallel process mixed effects regression models characterized longitudinal trajectories of cognitive variables and time-varying changes in brain volumes. Baseline age was associated with both memory and executive function at baseline (p's < 0.001) and change in memory and executive function performances over time (p's < 0.05). After adjusting for clinical diagnosis, baseline, and longitudinal changes in brain volume, and baseline levels of cerebrospinal fluid biomarkers, age effects on change in episodic memory and executive function were fully attenuated, age effects on baseline memory were substantially attenuated, but an association remained between age and baseline executive function. Results support previous studies that show that age effects on cognitive decline are fully mediated by disease and neurodegeneration variables but also show domain-specific age effects on baseline cognition, specifically an age pathway to executive function that is independent of brain and disease pathways. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial.

    PubMed

    Young, Sean D; Cumberland, William G; Lee, Sung-Jae; Jaganath, Devan; Szekeres, Greg; Coates, Thomas

    2013-09-03

    Social networking technologies are an emerging tool for HIV prevention. To determine whether social networking communities can increase HIV testing among African American and Latino men who have sex with men (MSM). Randomized, controlled trial with concealed allocation. (ClinicalTrials.gov: NCT01701206). Online. 112 MSM based in Los Angeles, more than 85% of whom were African American or Latino. Sixteen peer leaders were randomly assigned to deliver information about HIV or general health to participants via Facebook groups over 12 weeks. After participants accepted a request to join the group, participation was voluntary. Group participation and engagement were monitored. Participants could request a free, home-based HIV testing kit and completed questionnaires at baseline and 12-week follow-up. Participant acceptance of and engagement in the intervention and social network participation, rates of home-based HIV testing, and sexual risk behaviors. Almost 95% of intervention participants and 73% of control participants voluntarily communicated using the social platform. Twenty-five of 57 intervention participants (44%) requested home-based HIV testing kits compared with 11 of 55 control participants (20%) (difference, 24 percentage points [95% CI, 8 to 41 percentage points]). Nine of the 25 intervention participants (36%) who requested the test took it and mailed it back compared with 2 of the 11 control participants (18%) who requested the test. Retention at study follow-up was more than 93%. Only 2 Facebook communities were included for each group. Social networking communities are acceptable and effective tools to increase home-based HIV testing among at-risk populations. National Institute of Mental Health.

  1. The NuMAX Long Baseline Neutrino Factory Concept

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delahaye, J-P.; Ankenbrandt, C.; Bogacz, A.

    A Neutrino Factory where neutrinos of all species are produced in equal quantities by muon decay is described as a facility at the intensity frontier for exquisite precision providing ideal conditions for ultimate neutrino studies and the ideal complement to Long Baseline Facilities like LBNF at Fermilab. It is foreseen to be built in stages with progressively increasing complexity and performance, taking advantage of existing or proposed facilities at an existing laboratory like Fermilab. A tentative layout based on a recirculating linac providing opportunities for considerable saving is discussed as well as its possible evolution toward a muon collider ifmore » and when requested by Physics. Tentative parameters of the various stages are presented as well as the necessary R&D to address the technological issues and demonstrate their feasibility.« less

  2. Behavior analysis in consumer affairs: encouraging dental professionals to provide consumers with shielding from unnecessary X-ray exposure.

    PubMed

    Greene, B F; Neistat, M D

    1983-01-01

    An unobtrusive observation system was developed to determine the extent to which dental professionals in two communities provided lead shielding to patients during X-ray exams. A lengthy baseline revealed low and irregular provision of shielding among half of these professionals. Subsequently, a program was undertaken by a consumer's group in which these professionals were requested to provide shielding and were given confidential feedback regarding its use during the baseline period. The provision of shielding dramatically increased at all offices and was maintained throughout a follow-up period extending to more than 9 months after the program's implementation. Little or no generalized effect was observed in the occurrence of three collateral behaviors that were also assessed throughout the study.

  3. Behavior analysis in consumer affairs: encouraging dental professionals to provide consumers with shielding from unnecessary X-ray exposure.

    PubMed Central

    Greene, B F; Neistat, M D

    1983-01-01

    An unobtrusive observation system was developed to determine the extent to which dental professionals in two communities provided lead shielding to patients during X-ray exams. A lengthy baseline revealed low and irregular provision of shielding among half of these professionals. Subsequently, a program was undertaken by a consumer's group in which these professionals were requested to provide shielding and were given confidential feedback regarding its use during the baseline period. The provision of shielding dramatically increased at all offices and was maintained throughout a follow-up period extending to more than 9 months after the program's implementation. Little or no generalized effect was observed in the occurrence of three collateral behaviors that were also assessed throughout the study. PMID:6833165

  4. Using iPads to Teach Communication Skills of Students with Autism.

    PubMed

    Xin, Joy F; Leonard, Deborah A

    2015-12-01

    The purpose of this study was to examine the effects of using an iPad to assist students with autism in learning communication skills. Three, 10 years old learners diagnosed with autism who present little or no functional speech, participated in the study. A multiple baseline design with AB phases across academic and social settings was used. During the baseline, students were given access to an iPad with the SonoFlex speech-generating device application, while no communicative attempts were observed. During the intervention, the students were taught to use the iPad to communicate with their teacher and peers for 6 weeks. With a least-to-most prompting hierarchy, all students increased initiating requests, responding to questions and making social comments in both class and recess settings.

  5. The NuMAX Long Baseline Neutrino Factory concept

    DOE PAGES

    Delahaye, J-P.; Ankenbrandt, C. M.; Bogacz, S. A.; ...

    2018-06-01

    A Neutrino Factory where neutrinos of all species are produced in equal quantities by muon decay is described as a facility at the intensity frontier for exquisite precision providing ideal conditions for ultimate neutrino studies and the ideal complement to Long Baseline Facilities like LBNF at Fermilab. It is foreseen to be built in stages with progressively increasing complexity and performance, taking advantage of existing or proposed facilities at an existing laboratory like Fermilab. A tentative layout based on a recirculating linac providing opportunities for considerable saving is discussed as well as its possible evolution toward a muon collider ifmore » and when requested by Physics. Tentative parameters of the various stages are presented as well as the necessary R&D to address the technological issues and demonstrate their feasibility.« less

  6. The NuMAX Long Baseline Neutrino Factory concept

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delahaye, J-P.; Ankenbrandt, C. M.; Bogacz, S. A.

    A Neutrino Factory where neutrinos of all species are produced in equal quantities by muon decay is described as a facility at the intensity frontier for exquisite precision providing ideal conditions for ultimate neutrino studies and the ideal complement to Long Baseline Facilities like LBNF at Fermilab. It is foreseen to be built in stages with progressively increasing complexity and performance, taking advantage of existing or proposed facilities at an existing laboratory like Fermilab. A tentative layout based on a recirculating linac providing opportunities for considerable saving is discussed as well as its possible evolution toward a muon collider ifmore » and when requested by Physics. Tentative parameters of the various stages are presented as well as the necessary R&D to address the technological issues and demonstrate their feasibility.« less

  7. The NuMAX Long Baseline Neutrino Factory Concept

    DOE PAGES

    Delahaye, J-P.; Ankenbrandt, C.; Bogacz, A.; ...

    2018-06-12

    A Neutrino Factory where neutrinos of all species are produced in equal quantities by muon decay is described as a facility at the intensity frontier for exquisite precision providing ideal conditions for ultimate neutrino studies and the ideal complement to Long Baseline Facilities like LBNF at Fermilab. It is foreseen to be built in stages with progressively increasing complexity and performance, taking advantage of existing or proposed facilities at an existing laboratory like Fermilab. A tentative layout based on a recirculating linac providing opportunities for considerable saving is discussed as well as its possible evolution toward a muon collider ifmore » and when requested by Physics. Tentative parameters of the various stages are presented as well as the necessary R&D to address the technological issues and demonstrate their feasibility.« less

  8. Review of the President’s Fiscal Year 2009 Budget Request for the Defense Health Program’s Private Sector Care Budget Activity Group

    DTIC Science & Technology

    2008-05-28

    2009 budget request for the Defense Health Program’s Private Sector Care BAG. To do this, we reviewed (1) DOD’s justification for the request for the... Private Sector Care BAG, including the underlying estimates and the extent to which DOD considered historical information; and (2) changes between this...develop the budget requests for the Private Sector Care BAG in fiscal years 2008 and 2009. We also interviewed officials and analyzed documents from

  9. Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study.

    PubMed

    Yu, Edward; Papandreou, Christopher; Ruiz-Canela, Miguel; Guasch-Ferre, Marta; Clish, Clary B; Dennis, Courtney; Liang, Liming; Corella, Dolores; Fitó, Montserrat; Razquin, Cristina; Lapetra, José; Estruch, Ramón; Ros, Emilio; Cofán, Montserrat; Arós, Fernando; Toledo, Estefania; Serra-Majem, Lluis; Sorlí, José V; Hu, Frank B; Martinez-Gonzalez, Miguel A; Salas-Salvado, Jordi

    2018-06-08

    Metabolites of the tryptophan-kynurenine pathway (i.e., tryptophan, kynurenine, kynurenic acid, quinolinic acid, 3-hydroxyanthranilic) may be associated with diabetes development. Using a case-cohort design nested in the Prevención con Dieta Mediterránea (PREDIMED) study, we studied the associations of baseline and 1-year changes of these metabolites with incident type 2 diabetes (T2D). Plasma metabolite concentrations were quantified via LC-MS for n = 641 in a randomly selected subcohort and 251 incident cases diagnosed during 3.8 years of median follow-up. Weighted Cox models adjusted for age, sex, body mass index, and other T2D risk factors were used. Contrary to our hypothesis, baseline tryptophan was associated with higher risk of incident T2D (hazard ratio = 1.29; 95% CI, 1.04-1.61 per SD). Positive changes in quinolinic acid from baseline to 1 year were associated with a higher risk of T2D (hazard ratio = 1.39; 95% CI, 1.09-1.77 per SD). Baseline tryptophan and kynurenic acid were directly associated with changes in homeostatic model assessment for insulin resistance (HOMA-IR) from baseline to 1 year. Concurrent changes in kynurenine, quinolinic acid, 3-hydroxyanthranilic acid, and kynurenine/tryptophan ratio were associated with baseline-to-1-year changes in HOMA-IR. Baseline tryptophan and 1-year increases in quinolinic acid were positively associated with incident T2D. Baseline and 1-year changes in tryptophan metabolites predicted changes in HOMA-IR. © 2018 American Association for Clinical Chemistry.

  10. Weight change by baseline BMI from three-year observational data: findings from the Worldwide Schizophrenia Outpatient Health Outcomes Database.

    PubMed

    Bushe, Chris J; Slooff, Cees J; Haddad, Peter M; Karagianis, Jamie L

    2013-04-01

    The aim was to explore weight and body mass index (BMI) changes by baseline BMI in patients completing three years of monotherapy with various first- and second-generation antipsychotics in a large cohort in a post hoc analysis of three-year observational data. Data were analyzed by antipsychotic and three baseline BMI bands: underweight/normal weight (BMI <25 kg/m²), overweight (25-30 kg/m²) and obese (>30 kg/m²). Baseline BMI was associated with subsequent weight change irrespective of the antipsychotic given. Specifically, a smaller proportion of patients gained ≥7% baseline bodyweight, and a greater proportion of patients lost ≥7% baseline bodyweight with increasing baseline BMI. For olanzapine (the antipsychotic associated with highest mean weight gain in the total drug cohort), the percentage of patients gaining ≥7% baseline weight was 45% (95% CI: 43-48) in the underweight/normal weight BMI cohort and 20% (95% CI: 15-27) in the obese BMI cohort; 7% (95% CI: 6-8) of the underweight/normal cohort and 19% (95% CI: 13-27) of the obese cohort lost ≥7% baseline weight. BMI has an association with the likelihood of weight gain or loss and should be considered in analyses of antipsychotic weight change.

  11. An Analysis Of The Benefits And Application Of Earned Value Management (EVM) Project Management Techniques For Dod Programs That Do Not Meet Dod Policy Thresholds

    DTIC Science & Technology

    2017-12-01

    carefully to ensure only minimum information needed for effective management control is requested.  Requires cost-benefit analysis and PM...baseline offers metrics that highlights performance treads and program variances. This information provides Program Managers and higher levels of...The existing training philosophy is effective only if the managers using the information have well trained and experienced personnel that can

  12. Automated Computer Access Request System

    NASA Technical Reports Server (NTRS)

    Snook, Bryan E.

    2010-01-01

    The Automated Computer Access Request (AutoCAR) system is a Web-based account provisioning application that replaces the time-consuming paper-based computer-access request process at Johnson Space Center (JSC). Auto- CAR combines rules-based and role-based functionality in one application to provide a centralized system that is easily and widely accessible. The system features a work-flow engine that facilitates request routing, a user registration directory containing contact information and user metadata, an access request submission and tracking process, and a system administrator account management component. This provides full, end-to-end disposition approval chain accountability from the moment a request is submitted. By blending both rules-based and rolebased functionality, AutoCAR has the flexibility to route requests based on a user s nationality, JSC affiliation status, and other export-control requirements, while ensuring a user s request is addressed by either a primary or backup approver. All user accounts that are tracked in AutoCAR are recorded and mapped to the native operating system schema on the target platform where user accounts reside. This allows for future extensibility for supporting creation, deletion, and account management directly on the target platforms by way of AutoCAR. The system s directory-based lookup and day-today change analysis of directory information determines personnel moves, deletions, and additions, and automatically notifies a user via e-mail to revalidate his/her account access as a result of such changes. AutoCAR is a Microsoft classic active server page (ASP) application hosted on a Microsoft Internet Information Server (IIS).

  13. 77 FR 46683 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) School...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ... Bureau plans to request clearance for updating the universe of collection of data concerning the school... based on current trends in school enrollment for people over 24. This change in universe will result in...

  14. 78 FR 14838 - Proposed Information Collection Request of the Resource Justification Model (RJM); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-07

    ... submissions of responses. III. Current Actions Type of Review: Extension without change. Title: Resource... hours........ 424 hours. TOTALS 212 6,519 hrs Total Burden Cost (capital/startup): $0. Total Burden Cost...

  15. 40 CFR 63.1417 - Reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... compliance with the requirements of this subpart, or changes in methods or equipment for monitoring... submitted on electronic media. (d) Precompliance Report. Owners or operators of affected sources requesting an extension for compliance; requesting approval to use alternative monitoring parameters...

  16. Defense: FY2017 Budget Request, Authorization, and Appropriations

    DTIC Science & Technology

    2016-04-12

    for FY2016. In addition to the base budget request, the Administration requested $58.8 billion—including $3.4 billion for the European Reassurance...than by enlarging their numbers. Congressional deliberations on the FY2017 defense budget may be influenced, in part, by the broader budget...changing their organization rather than by enlarging their numbers; and  emphasizing innovation. A number of observers have called for DOD to be

  17. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  18. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  19. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  20. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  1. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  2. Growing an ethics consultation service: A longitudinal study examining two decades of practice.

    PubMed

    Gorka, Christine; Craig, Jana M; Spielman, Bethany J

    2017-01-01

    Little is known about what factors may contribute to the growth of a consultation service or how a practice may change or evolve across time. This study examines data collected from a busy ethics consultation service over a period of more than two decades. We report a number of longitudinal findings that represent significant growth in the volume of ethics consultation requests from 19 in 1990 to 551 in 2013, as well as important changes in the patient population for which ethics help is requested. The findings include (1) a steady growth in requests from primary care providers (e.g., physicians and nurses), as well as increases in ancillary services (e.g., social workers); (2) a decrease in length of stay (days) before ethics help is requested; (3) an increase in the reasons that individuals ask for help from ethics; (4) an upsurge in consults requests from areas outside the intensive care unit (ICU); (5) a decrease in patients that died during hospitalization (e.g., live discharges); and (6) growth in the numbers of patients lacking decision-making capacity. We believe the increases in consult requests reflect appropriate and necessary growth because recent consultations have also been associated with consultations requiring (7) additional interventions and (8) reasonably high time intensity scores.

  3. Assessment of Air Traffic Controller Acceptability of Aircrew Route Change Requests

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Enea, Gabriele; Burke, Kelly; Wing, David

    2017-01-01

    NASA developed the traffic aware strategic aircrew requests concept for a cockpit automation that identifies route improvements and advises the aircrew to request the change from the air traffic controller. In order to increase the chance of air traffic control approval, the automation ensures that the route is clear of known traffic, weather, and airspace restrictions. Hence the technology is anticipated to provide benefits in areas such as flight efficiency, flight schedule compliance, passenger comfort, and pilot and controller workload. In support of a field trial of a prototype of the technology, observations were conducted at the Atlanta and Jacksonville air traffic control centers to identify the main factors that affect the acceptability of aircrew requests by air traffic controllers. Observers shadowed air traffic controllers as the test flight pilot made pre-scripted requests to invoke acceptability issues and then they interviewed voluntarily fifty controllers with experience ranging from one to thirty-five years. The most common reason for rejecting requests is conflicting with traffic followed by violating air traffic procedures, increasing sector workload, and conflicting with major arrival and departure flows and flow restrictions. Quantitative parameters such as the distance that a route should maintain from sector boundaries and special use airspace were identified and recommended for inclusion in the automation.

  4. Heat engine generator control system

    DOEpatents

    Rajashekara, K.; Gorti, B.V.; McMullen, S.R.; Raibert, R.J.

    1998-05-12

    An electrical power generation system includes a heat engine having an output member operatively coupled to the rotor of a dynamoelectric machine. System output power is controlled by varying an electrical parameter of the dynamoelectric machine. A power request signal is related to an engine speed and the electrical parameter is varied in accordance with a speed control loop. Initially, the sense of change in the electrical parameter in response to a change in the power request signal is opposite that required to effectuate a steady state output power consistent with the power request signal. Thereafter, the electrical parameter is varied to converge the output member speed to the speed known to be associated with the desired electrical output power. 8 figs.

  5. Heat engine generator control system

    DOEpatents

    Rajashekara, Kaushik; Gorti, Bhanuprasad Venkata; McMullen, Steven Robert; Raibert, Robert Joseph

    1998-01-01

    An electrical power generation system includes a heat engine having an output member operatively coupled to the rotor of a dynamoelectric machine. System output power is controlled by varying an electrical parameter of the dynamoelectric machine. A power request signal is related to an engine speed and the electrical parameter is varied in accordance with a speed control loop. Initially, the sense of change in the electrical parameter in response to a change in the power request signal is opposite that required to effectuate a steady state output power consistent with the power request signal. Thereafter, the electrical parameter is varied to converge the output member speed to the speed known to be associated with the desired electrical output power.

  6. Changing effects of direct-to-consumer broadcast drug advertising information sources on prescription drug requests.

    PubMed

    Lee, Annisa Lai

    2009-06-01

    This study tracks the changes of the effects of 4 information sources for direct-to-consumer drug advertising on patients' requests for prescription drugs from physicians since the inception of the "Guidance for Industry about Consumer-directed Broadcast Advertisements." The Guidance advises pharmaceuticals to use four information sources for consumers to seek further information to supplement broadcast drug advertisements: small-print information, the Internet, a toll-free number, and health-care providers (nurses, doctors, and pharmacists). Logistic models were created by using survey data collected by the Food and Drug Administration in 1999 and 2002. Results show that throughout the years, health-care providers remain the most used and strongest means associated with patients' direct requests for nonspecific and specific prescription drugs from doctors. The small-print information source gains power and changes from an indirect means associated with patients' discussing drugs with health-care providers to a direct means associated with patients' asking about nonspecific and specific drugs from their doctors. The Internet is not directly related to drug requests, but the effect of its association with patients seeking information from health-care providers grew 11-fold over the course of the study. The toll-free number lost its power altogether for both direct request for a prescription drug and further discussion with health-care providers. Patient demographics will be considered for specific policy implications.

  7. The Work Ability Index as a screening tool to identify the need for rehabilitation: longitudinal findings from the Second German Sociomedical Panel of Employees.

    PubMed

    Bethge, Matthias; Radoschewski, Friedrich Michael; Gutenbrunner, Christoph

    2012-11-01

    To evaluate the predictive value of the Work Ability Index (WAI) for different indicators of the need for rehabilitation at 1-year follow-up. Cohort study. Data were obtained from the Second German Sociomedical Panel of Employees, a large-scale cohort study with postal surveys in 2009 and 2010. A total of 457 women and 579 men were included. Confirmatory factor analysis confirmed the one-dimensionality of the WAI. Regression analyses showed that poor and moderate baseline WAI scores were associated with lower health-related quality of life and more frequent use of primary healthcare 1 year later. Subjects with poor baseline work ability had 4.6 times higher odds of unemployment and 12.2 times higher odds of prolonged sick leave than the reference group with good or excellent baseline work ability. Moreover, the odds of subjectively perceived need for rehabilitation, intention to request rehabilitation and actual use of rehabilitation services were 9.7, 5.7 and 3 times higher in the poor baseline WAI group and 5.5, 4 and 1.8 times higher in the moderate baseline WAI group, respectively. A WAI score ≤ 37 was identified as the optimal cut-off to predict the need for rehabilitation. The WAI is a valid screening tool for identifying the need for rehabilitation.

  8. Los Alamos National Laboratory and Lawrence Livermore National Laboratory Plutonium Sustainment Monthly Program Report September 2012

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McLaughlin, Anastasia Dawn; Storey, Bradford G.; Bowidowicz, Martin

    In March of 2012 the Plutonium Sustainment program at LANL completed or addressed the following high-level activities: (1) Delivered Revision 2 of the Plutonium Sustainment Manufacturing Study, which incorporated changes needed due to the release of the FY2013 President's Budget and the delay in the Chemistry and Metallurgy Research Replacement Nuclear Facility (CMRRNF). (2) W87 pit type development activities completed a detailed process capability review for the flowsheet in preparation for the Engineering Development Unit Build. (3) Completed revising the Laser Beam Welding schedule to address scope and resource changes. (4) Completed machining and inspecting the first set of high-fidelitymore » cold parts on Precitech 2 for Gemini. (5) The Power Supply Assembly Area started floor cutting with a concrete saw and continued legacy equipment decommissioning. There are currently no major issues associated with achieving MRT L2 Milestones 4195-4198 or the relevant PBIs associated with Plutonium Sustainment. There are no budget issues associated with FY12 final budget guidance. Table 1 identifies all Baseline Change Requests (BCRs) that were initiated, in process, or completed during the month. The earned value metrics overall for LANL are within acceptable thresholds, so no high-level recovery plan is required. Each of the 5 major LANL WBS elements is discussed in detail.« less

  9. Impact of peer review on reports of randomised trials published in open peer review journals: retrospective before and after study

    PubMed Central

    Collins, Gary S; Boutron, Isabelle; Yu, Ly-Mee; Cook, Jonathan; Shanyinde, Milensu; Wharton, Rose; Shamseer, Larissa; Altman, Douglas G

    2014-01-01

    Objective To investigate the effectiveness of open peer review as a mechanism to improve the reporting of randomised trials published in biomedical journals. Design Retrospective before and after study. Setting BioMed Central series medical journals. Sample 93 primary reports of randomised trials published in BMC-series medical journals in 2012. Main outcome measures Changes to the reporting of methodological aspects of randomised trials in manuscripts after peer review, based on the CONSORT checklist, corresponding peer reviewer reports, the type of changes requested, and the extent to which authors adhered to these requests. Results Of the 93 trial reports, 38% (n=35) did not describe the method of random sequence generation, 54% (n=50) concealment of allocation sequence, 50% (n=46) whether the study was blinded, 34% (n=32) the sample size calculation, 35% (n=33) specification of primary and secondary outcomes, 55% (n=51) results for the primary outcome, and 90% (n=84) details of the trial protocol. The number of changes between manuscript versions was relatively small; most involved adding new information or altering existing information. Most changes requested by peer reviewers had a positive impact on the reporting of the final manuscript—for example, adding or clarifying randomisation and blinding (n=27), sample size (n=15), primary and secondary outcomes (n=16), results for primary or secondary outcomes (n=14), and toning down conclusions to reflect the results (n=27). Some changes requested by peer reviewers, however, had a negative impact, such as adding additional unplanned analyses (n=15). Conclusion Peer reviewers fail to detect important deficiencies in reporting of the methods and results of randomised trials. The number of these changes requested by peer reviewers was relatively small. Although most had a positive impact, some were inappropriate and could have a negative impact on reporting in the final publication. PMID:24986891

  10. Job strain and changes in the body mass index among working women: A prospective study

    PubMed Central

    Fujishiro, Kaori; Lawson, Christina C.; Hibert, Eileen Lividoti; Chavarro, Jorge E.; Rich-Edwards, Janet W.

    2015-01-01

    Objectives The relationship between job strain and weight gain has been unclear, especially for women. Using data from over 52 000 working women, we compare the association between change in job strain and change in BMI across different levels of baseline BMI. Subjects/Methods We used data from participants in the Nurses’ Health Study II (n=52 656, mean age = 38.4), an ongoing prospective cohort study. Using linear regression, we modeled the change in BMI over 4 years as a function of the change in job strain, baseline BMI, and the interaction between the two. Change in job strain was characterized in four categories combining baseline and follow-up levels: consistently low strain [low at both points], decreased strain [high strain at baseline only], increased strain [high strain at follow-up only], and consistently high strain [high at both points]. Age, race/ethnicity, pregnancy history, job types, and health behaviors at baseline were controlled for in the model. Results In adjusted models, women who reported high job strain at least once during the four-year period had a greater increase in BMI (ΔBMI=0.06–0.12, p<0.05) than those who never reported high job strain. The association between the change in job strain exposure and the change in BMI depended on the baseline BMI level (p=0.015 for the interaction): the greater the baseline BMI, the greater the BMI gain associated with consistently high job strain. The BMI gain associated with increased or decreased job strain was uniform across the range of baseline BMI. Conclusions Women with higher BMI may be more vulnerable to BMI gain when exposed to constant work stress. Future research focusing on mediating mechanisms between job strain and BMI change should explore the possibility of differential responses to job strain by initial BMI. PMID:25986779

  11. 76 FR 52934 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... Auxiliary members report observations of changes that require additions, corrections or revisions to... writing Diana Hynek, Departmental Paperwork Clearance Officer, (202) 482-0266, Department of Commerce...

  12. 78 FR 60826 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... groundfish fishing behavior and possible responses to potential regulatory changes. Affected Public... writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  13. 76 FR 67454 - Agency Information Collection Request; 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... revising the collection to include changes adopted by the cross-agency R&R working group. This working... Assistance (Cover); R&R Personal Data; R&R Senior/Key Person Profile; R&R Senior/Key Person Profile (Expanded...

  14. Association between objective and subjective binge eating and psychopathology during a psychological treatment trial for bulimic symptoms.

    PubMed

    Goldschmidt, Andrea B; Accurso, Erin C; Crosby, Ross D; Cao, Li; Ellison, Jo; Smith, Tracey L; Klein, Marjorie H; Mitchell, James E; Crow, Scott J; Wonderlich, Stephen A; Peterson, Carol B

    2016-12-01

    Although loss of control (LOC) while eating is a core construct of bulimia nervosa (BN), questions remain regarding its validity and prognostic significance independent of overeating. We examined trajectories of objective and subjective binge eating (OBE and SBE, respectively; i.e., LOC eating episodes involving an objectively or subjectively large amount of food) among adults participating in psychological treatments for BN-spectrum disorders (n = 80). We also explored whether changes in the frequency of these eating episodes differentially predicted changes in eating-related and general psychopathology and, conversely, whether changes in eating-related and general psychopathology predicted differential changes in the frequency of these eating episodes. Linear mixed models with repeated measures revealed that OBE decreased twice as rapidly as SBE throughout treatment and 4-month follow-up. Generalized linear models revealed that baseline to end-of-treatment reductions in SBE frequency predicted baseline to 4-month follow-up changes in eating-related psychopathology, depression, and anxiety, while changes in OBE frequency were not predictive of psychopathology at 4-month follow-up. Zero-inflation models indicated that baseline to end-of-treatment changes in eating-related psychopathology and depression symptoms predicted baseline to 4-month follow-up changes in OBE frequency, while changes in anxiety and self-esteem did not. Baseline to end-of-treatment changes in eating-related psychopathology, self-esteem, and anxiety predicted baseline to 4-month follow-up changes in SBE frequency, while baseline to end-of-treatment changes in depression did not. Based on these findings, LOC accompanied by objective overeating may reflect distress at having consumed an objectively large amount of food, whereas LOC accompanied by subjective overeating may reflect more generalized distress related to one's eating- and mood-related psychopathology. BN treatments should comprehensively target LOC eating and related psychopathology, particularly in the context of subjectively large episodes, to improve global outcomes. Copyright © 2016. Published by Elsevier Ltd.

  15. Estradiol valerate plus dienogest versus ethinylestradiol plus levonorgestrel for the treatment of primary dysmenorrhea.

    PubMed

    Petraglia, Felice; Parke, Susanne; Serrani, Marco; Mellinger, Uwe; Römer, Thomas

    2014-06-01

    To demonstrate the superiority of estradiol valerate plus dienogest (E(2)V/DNG) over ethinylestradiol plus levonorgestrel (EE/LNG) in reducing the number of days with dysmenorrheic pain among women with primary dysmenorrhea. In a phase IIIb trial conducted at 44 centers worldwide between April 2009 and November 2010, otherwise healthy women aged 14-50 years requesting contraception were randomized to daily oral administration of E(2)V/DNG (n = 253) or EE/LNG (n = 254) for three 28-daycycles. The primary efficacy variable was number of days with dysmenorrheic pain, the category of which (none, mild, moderate, severe) was self-assessed on a daily basis (irrespective of menstrual bleeding status) and recorded on diary cards. Notably, the women documented their pain as they experienced it before taking any (permitted) rescue medication. Overall, 217 and 209 women receiving E(2)V/DNG and EE/LNG, respectively, completed the study. The mean ± SD change from baseline in number of days with dysmenorrheic pain was -4.6 ± 4.6 days and -4.2 ± 4.2 days for the E(2)V/DNG and EE/LNG groups, respectively (P = 0.34). Both E(2)V/DNG and EE/LNG led to considerable relief of dysmenorrheic complaints among women with primary dysmenorrhea, decreasing the number of days with dysmenorrheic pain from baseline to a similar extent. ClinicalTrials.gov:NCT00909857. Copyright © 2014 International Federation of Gynecology and Obstetrics. All rights reserved.

  16. Association of Hemoglobin A1c and Wound Healing in Diabetic Foot Ulcers.

    PubMed

    Fesseha, Betiel K; Abularrage, Christopher J; Hines, Kathryn F; Sherman, Ronald; Frost, Priscilla; Langan, Susan; Canner, Joseph; Likes, Kendall C; Hosseini, Sayed M; Jack, Gwendolyne; Hicks, Caitlin W; Yalamanchi, Swaytha; Mathioudakis, Nestoras

    2018-04-16

    This study evaluated the association between hemoglobin A 1c (A1C) and wound outcomes in patients with diabetic foot ulcers (DFUs). We conducted a retrospective analysis of an ongoing prospective, clinic-based study of patients with DFUs treated at an academic institution during a 4.7-year period. Data from 270 participants and 584 wounds were included in the analysis. Cox proportional hazards regression was used to assess the incidence of wound healing at any follow-up time in relation to categories of baseline A1C and the incidence of long-term (≥90 days) wound healing in relation to tertiles of nadir A1C change and mean A1C change from baseline, adjusted for potential confounders. Baseline A1C was not associated with wound healing in univariate or fully adjusted models. Compared with a nadir A1C change from baseline of -0.29 to 0.0 (tertile 2), a nadir A1C change of 0.09 to 2.4 (tertile 3) was positively associated with long-term wound healing in the subset of participants with baseline A1C <7.5% (hazard ratio [HR], 2.07; 95% CI, 1.08-4.00), but no association with wound healing was seen with the mean A1C change from baseline in this group. Neither nadir A1C change nor mean A1C change were associated with long-term wound healing in participants with baseline A1C ≥7.5%. There does not appear to be a clinically meaningful association between baseline or prospective A1C and wound healing in patients with DFUs. The paradoxical finding of accelerated wound healing and increase in A1C in participants with better baseline glycemic control requires confirmation in further studies. © 2018 by the American Diabetes Association.

  17. Weaknesses in the Resident Language Training System of Defense Language Institute Affect the Quality of Trained Linguists

    DTIC Science & Technology

    1982-05-06

    request of- " -a)1LjrLetmmanZeon -E- -Pemetta. GAO’s objec- / tives were to identify and analyze signif - icant internal Defense Language Institute...as a baseline from which to measure vari- ances, assess the reasons for variances , and make needed correc- tions. We were told that DLI had not...etc. Multiply these major efforts times the number of high density "threat" languages and one can better understand the nature of manpower expenditures

  18. Request for Information Response for the Flight Validation of Adaptive Control to Prevent Loss-of-Control Events. Overview of RFI Responses

    NASA Technical Reports Server (NTRS)

    Bosworth, John T.

    2009-01-01

    Adaptive control should be integrated with a baseline controller and only used when necessary (5 responses). Implementation as an emergency system. Immediately re-stabilize and return to controlled flight. Forced perturbation (excitation) for fine-tuning system a) Check margins; b) Develop requirements for amplitude of excitation. Adaptive system can improve performance by eating into margin constraints imposed on the non-adaptive system. Nonlinear effects due to multi-string voting.

  19. Availability of illicit tobacco in small retail outlets before and after the implementation of Australian plain packaging legislation.

    PubMed

    Scollo, Michelle; Bayly, Megan; Wakefield, Melanie

    2015-03-01

    We aimed to assess change in the availability of illicit tobacco in small mixed business retail outlets following the December 2012 introduction of plain packaging in Australia. 303 small retail outlets were visited in June and September 2012 (baseline months), and in December 2012 and February, April and July 2013. Fieldworkers requested a particular low-cost brand of cigarettes and then pressed the retailer for an 'even cheaper' brand. The cheapest pack of cigarettes offered was purchased and later examined to assess any divergence from prescribed Australian packaging regulations. The price paid was compared with tax liability and recommended retail price for the particular brand and pack size. In a sub-set of 179 stores, fieldworkers then asked the retailer about availability of unbranded (chop-chop) tobacco. Thirteen (2.2%) of 598 packs purchased pre-plain packaging were either non-compliant with Australian health warnings and/or suspiciously priced. Four packs (1.3%) of 297 met either or both criteria in the December implementation month, and five (0.6%) of 878 did so in the three collection months following implementation. Chop-chop was offered upon enquiry on 0.6% (n=2) of 338 occasions prior to implementation, 0.6% (n=1) of 170 occasions in the December 2012 implementation month, and 0.6% (n=3) of 514 occasions postimplementation. The likelihood of a 'positive' response (either an offer to sell or information about where unbranded tobacco may be purchased) did not differ across preimplementation, during-implementation and postimplementation waves. Overall, packs judged likely to be illicit were sold in response to requests for cheapest available packs on fewer than one percent of occasions. Offers to sell unbranded tobacco were rare. No change in availability of illicit tobacco was observed following implementation of plain packaging. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  20. 1997 Monitoring report for the Gunnison, Colorado Wetlands Mitigation Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-11-01

    Under the Uranium Mill Tailings Remedial Action (UMTRA) Project, the U.S. Department of Energy (DOE) cleaned up uranium mill tailings and other surface contamination near the town of Gunnison, Colorado. Remedial action resulted in the elimination of 4.3 acres (ac) (1.7 hectares [ha]) of wetlands. This loss is mitigated by the enhancement of six spring-fed areas on Bureau of Land Management (BLM) land (mitigation sites). Approximately 254 ac (1 03.3 ha) were fenced at the six sites to exclude grazing livestock. Of the 254 ac (103.3 ha), 17.8 ac (7.2 ha) are riparian plant communities; the rest are sagebrush communities.more » Baseline grazed conditions of the riparian plant communities at the mitigation sites were measured prior to fencing. This report discusses results of the fourth year of a monitoring program implemented to document the response of vegetation and wildlife to the exclusion of livestock. Three criteria for determining success of the mitigation were established: plant height, vegetation density (bare ground), and vegetation diversity. By 1996, Prospector Spring, Upper Long`s Gulch, and Camp Kettle met the criteria. The DOE requested transfer of these sites to BLM for long-term oversight. The 1997 evaluation of the three remaining sites, discussed in this report, showed two sites (Houston Gulch and Lower Long`s Gulch) meet the criteria. The DOE will request the transfer of these two sites to the BLM for long-term oversight. The last remaining site, Sage Hen Spring, has met only two of the criteria (percent bare ground and plant height). The third criterion, vegetation diversity, was not met. The vegetation appears to be changing from predominantly wet species to drier upland species, although the reason for this change is uncertain. It may be due to below-normal precipitation in recent years, diversion of water from the spring to the stock tank, or manipulation of the hydrology farther up gradient.« less

  1. 76 FR 10366 - Agency Information Collection Request; 60-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ...). Abstract: This research leverages best practices in behavior change, interaction design, and service innovation to increase the understanding and adoption of Comparative Effectiveness Research (CER) information..., translation, and adoption of evidence-based, outcomes- oriented CER findings. Comparative Effectiveness...

  2. 76 FR 72673 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-25

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... certificates, and 30 minutes for certificate change notifications and exception to procedures. Needs and Uses... writing Diana Hynek, Departmental Paperwork Clearance Officer, (202) 482-0266, Department of Commerce...

  3. 78 FR 20296 - Proposed Information Collection; Comment Request; Marine Recreational Information Program Fishing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... Collection; Comment Request; Marine Recreational Information Program Fishing Effort Survey AGENCY: National... title will be changed from ``Marine Recreational Information Program'' to ``Marine Recreational Information Program Fishing Effort Survey''. Marine recreational anglers are surveyed to collect catch and...

  4. 75 FR 38090 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... DEPARTMENT OF DEFENSE Department of the Army [Docket ID USA-2010-0016] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army, (OAA-AAHS-RDR... without change, including any personal identifiers or contact information. FOR FURTHER INFORMATION CONTACT...

  5. 78 FR 50491 - Agency Information Collection Activities: Information Collection Renewal; Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... 20219. SUPPLEMENTARY INFORMATION: The OCC is requesting an extension, without change, of the following... requirements. The information collection requirements ensure that national banks and Federal savings... banking statutes and regulations. The information is necessary for regulatory and examination purposes...

  6. 77 FR 31017 - Office of Facilities Management and Program Services; Information Collection; Background...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... a Basic National Agency Check Criminal History, GSA Form 176; and 2. Two sets of fingerprints on FBI Fingerprint Cards, for FD-258. This is not a request to collect new information, this is a request to change...

  7. Comparison of baseline-referenced versus norm-referenced analytical approaches for in-theatre assessment of mild traumatic brain injury neurocognitive impairment.

    PubMed

    Haran, F Jay; Dretsch, Michael N; Slaboda, Jill C; Johnson, Dagny E; Adam, Octavian R; Tsao, Jack W

    2016-01-01

    To examine differences between the baseline-referenced and norm-referenced approaches for determining decrements in Automated Neuropsychological Assessment Metrics Version 4 TBI-MIL (ANAM) performance following mild traumatic brain injury (mTBI). ANAM data were reviewed for 616 US Service members, with 528 of this sample having experienced an mTBI and 88 were controls. Post-injury change scores were calculated for each sub-test: (1) normative change score = in-theater score - normative mean and (2) baseline change score = in-theater score - pre-deployment baseline. Reliable change cut-scores were applied to the change and the resulting frequency distributions were compared using McNemar tests. Receiver operator curves (ROC) using both samples (i.e. mTBI and control) were calculated for the change scores for each approach to determine the discriminate ability of the ANAM. There were no statistical differences, p < 0.05 (Bonferonni-Holm corrected), between the approaches. When the area under the curve for the ROCs were averaged across sub-tests, there were no significant differences between either the norm-referenced (0.65) or baseline-referenced (0.66) approaches, p > 0.05. Overall, the findings suggest there is no clear advantage of using the baseline-referenced approach over norm-referenced approach.

  8. Social networking technologies as emerging tools for HIV prevention: A Cluster Randomized Trial

    PubMed Central

    Young, Sean D.; Cumberland, William G.; Lee, Sung-Jae; Jaganath, Devan; Szekeres, Greg; Coates, Thomas

    2013-01-01

    Background Social networking technologies are an emerging tool for HIV prevention. Objective To determine whether social networking communities can increase HIV testing among African American and Latino men who have sex with men (MSM). Design Randomized; controlled trial with concealed allocation (ClinicalTrials.gov: NCT01701206). Setting Online. Patients 112 MSM based in Los Angeles, more than 85% of whom were African American or Latino. Intervention Sixteen peer leaders were randomly assigned to deliver information about HIV or general health to participants via Facebook groups over 12 weeks. After participants accepted a request to join the group, participation was voluntary. Group participation and engagement was monitored. Participants could request a free home-based HIV testing kit and completed questionnaires at baseline and 12-week follow-up. Measurements Participant acceptance of and engagement in the intervention and social network participation, rates of home-based HIV testing, and sexual risk behaviors. Results Almost 95% of intervention participants and 73% of control participants voluntarily communicated using the social platform. Twenty-five of the 57 intervention participants (44%) requested home-based HIV testing kits compared with 11 of 55 control participants (20%) (difference, 24 percentage points [95% CI, 8 to 41 percentage points]). Nine of the 25 intervention participants (36%) who requested the test took it and mailed it back compared with 2 of the 11 control participants (18%) who requested the test. Retention at study follow-up was more 93%. Limitations Only 2 Facebook communities were included for each group. Conclusions Social networking communities are acceptable and effective tools to increase home-based HIV testing among at-risk populations. Primary funding source National Institute of Mental Health ClinicalTrials.gov Identifier (NCT01701206) PMID:24026317

  9. Factors that influence patient response to requests to change to a unified restrictive formulary.

    PubMed

    Smetana, Gerald W; Davis, Roger B; Phillips, Russell S

    2004-12-01

    To determine factors that influence patient willingness to accept a medication change to a unified, restrictive formulary. Prospective cohort study. University-affiliated hospital-based primary care internal medicine practice. Two hundred ninety-seven members of a managed care plan who had received a prescription for a nonformulary medication in the previous 4 months and whose primary care physician approved a conversion to a formulary medication. Clinical nurses invited patients to change to a formulary medication at the time of a telephone refill request based on a standard script. The overall conversion rate to the formulary medication was 59.8%. Seventy-four percent of patients who requested a refill by telephone converted to the formulary (odds ratio [OR], 2.24; 95% confidence interval [CI], 1.02 to 4.72). Patient age (OR, 1.03; CI, 1.01 to 1.05) and male gender (OR, 2.00; CI, 1.09 to 3.67) were each significant correlates of conversion. After adjustment in a multivariable model, only telephone refill request (adjusted OR, 2.31; CI, 1.07 to 4.97) and age (adjusted OR, 1.03; CI, 1.01 to 1.06) remained significant. Among the patients who made a telephone refill request, those who converted were more likely to completely trust their physician's judgment (P=.04) and to trust their physician to put their health over cost concerns (P=.05). Formulary conversion reduced costs beginning 3 months after the conversion date. A protocol for encouraging conversion to a unified formulary at the point of a telephone refill request increases formulary compliance rates and reduces medication costs. Patients who decline to convert medications are less likely to trust their physician.

  10. Sexual and Contraceptive Behaviors among Adolescents Requesting Emergency Contraception.

    PubMed

    Cwiak, Carrie; Howard, Brandon; Hsieh, Jennifer; Ricciotti, Nancy; Sucato, Gina S

    2016-12-01

    Unintended pregnancy rates in the United States remain high among adolescents. Emergency contraception (EC) provides the only option for pregnancy prevention after unprotected sex. To better define the population of adolescents who request and use EC pills, we performed a post hoc analysis of an over-the-counter simulation study of EC pills. Teen reproductive health clinics in 5 cities. Adolescents between the ages of 13 and 17 years who requested EC. Single-tablet levonorgestrel 1.5 mg. We calculated the correlations between age and baseline sexual and contraceptive behaviors. χ 2 Tests were used to compare behaviors of first-time and repeat EC users. Overall, the most commonly reported contraceptive methods ever used were condoms, oral contraceptives, none, and withdrawal; the most common method ever used in each age group was no method for 13- to 14-year-olds and condom for 15-, 16-, and 17-year-olds. The percentage of participants who had never used contraception before requesting EC decreased with age (53% [20/28] of 13- to 14-year-olds vs 15% [10/65] of 17-year-olds). First-time EC users were more likely to report no previous contraceptive use compared with repeat EC users (42% [88/208] vs 10% [13/135]; P < .001). Regardless of age, the most commonly reported reason for requesting EC was nonuse of any contraceptive method (ie, "unprotected sex"). Adolescents who requested EC most commonly reported ever-use of contraceptive methods that rely on user adherence or no method at all, with younger adolescents more likely than older adolescents to have used no previous method. The provision of EC presents an opportunity to provide education and access to highly effective, long-term contraceptive methods. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  11. Requests for electroencephalography in a district general hospital: retrospective and prospective audit

    PubMed Central

    Smith, D; Bartolo, R; Pickles, R M; Tedman, B M

    2001-01-01

    Objectives To determine the number of inappropriate requests for electroencephalography (EEG) and whether guidelines on use could reduce this number. Design Audit with retrospective and prospective components. Setting EEG department in district general hospital and centre for neurology and neurosurgery. Participants Retrospective: 368 at the general hospital and 143 patients at the neurology centre. Prospective: 241 patients undergoing EEG at the general hospital. Interventions Guidelines for EEG issued to users of service at the general hospital. Outcomes Retrospective: differences in requesting practice, result in different clinical scenarios, relative roles of procedure, clinical acumen in establishing diagnosis, usefulness of procedure. Prospective: change of requesting practice, impact on use. Results There were considerable differences in requesting practice. Non-specialists seem to use EEG as a diagnostic tool, especially in patients with “funny turns,” when it is much more likely to yield potentially misleading than clinically useful information. The overall proportion of procedures considered to influence management, to be justifiable, and to be inappropriate were 16% (59), 28.3% (104), and 55.7% (205), respectively. In the prospective study the total number of requests was significantly reduced (χ2=33.85, df=5, P<0.0001), mainly because of fewer requests in patients with non-specific “funny turns” (χ2=21.90, df=6, P=0.0013). There was a concomitant change in the usefulness of EEG (χ2 =26.99, df=2, P<0.0001). Conclusions This original audit informed clinical practice and had potential benefits for patients, clinicians, and provision of service. Systematic replication of this project, possibly on a regional basis, could result in financial savings, which would allow development of accessible local neurophysiology services. What is already known on this topicThere is unrestricted access to EEG in most district general hospitals throughout the United KingdomThe combination of equivocal symptoms and non-specific abnormalities carries a risk of misdiagnosis of epilepsyWhat this study addsAn audit of requests for EEG showed that a large proportion were inappropriate, mainly because of the prevalent misconception that the procedure could prove or exclude a diagnosis of epilepsy in patients with “funny turns”After intervention with clinicians, which used an educative approach, there was a considerable and sustained change in requesting practice PMID:11312226

  12. 15 CFR 752.10 - Changes to the SCL.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... request for each end-user. Example: end-user XXX is to be “added” and end-user AAA is to be “changed” from... Blocks 1 and 19. In Block 21, cite the end-user requirement or condition (i.e., end-user XXX is requested...

  13. 15 CFR 752.10 - Changes to the SCL.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... request for each end-user. Example: end-user XXX is to be “added” and end-user AAA is to be “changed” from... Blocks 1 and 19. In Block 21, cite the end-user requirement or condition (i.e., end-user XXX is requested...

  14. 15 CFR 752.10 - Changes to the SCL.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... request for each end-user. Example: end-user XXX is to be “added” and end-user AAA is to be “changed” from... Blocks 1 and 19. In Block 21, cite the end-user requirement or condition (i.e., end-user XXX is requested...

  15. 15 CFR 752.10 - Changes to the SCL.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... request for each end-user. Example: end-user XXX is to be “added” and end-user AAA is to be “changed” from... Blocks 1 and 19. In Block 21, cite the end-user requirement or condition (i.e., end-user XXX is requested...

  16. 76 FR 24006 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... provide low-income parents residing in the District of Columbia with expanded options for the education of... authorizing statute requires the mandated evaluation to address changes in parents' school involvement and... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests AGENCY: Department of...

  17. 76 FR 48801 - Submission for OMB Review; Comment Request

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    2011-08-09

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... responsibility over its portfolio. The revision involves a change in reporting including 100% electronic... Clearance Officer, (202) 482-0266, Department of Commerce, Room 6616, 14th and Constitution Avenue, NW...

  18. 77 FR 70416 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... that the requirements of the Magnuson-Stevens Act are being met. Change: Adobe fillable nomination kits... writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  19. 76 FR 60127 - Submission for OMB Review; Comment Request

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    2011-09-28

    ... plan administrators will use these forms to submit requests of; changes to their account information... Department of the Treasury will submit the following public information collection requirements to OMB for... Officer listed. Comments regarding these information collections should be addressed to the OMB reviewer...

  20. 77 FR 25706 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... ensure that requested data can be provided in the desired format, reporting burden (time and financial... sections of the collection instrument to reflect changes in the performance measures as approved by OMB and which will capture appropriate data for the Corporation's required performance measurement reporting...

  1. 48 CFR 243.205-71 - Requests for equitable adjustment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requests for equitable adjustment. 243.205-71 Section 243.205-71 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.205-71...

  2. 17 CFR 242.303 - Record preservation requirements for alternative trading systems.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... malfunctions, changes to system procedures, maintenance of hardware and software, instructions pertaining to... will be surrendered promptly on request of the alternative trading system, and shall include the... alternative trading system shall furnish to any representative of the Commission promptly upon request...

  3. 15 CFR 752.10 - Changes to the SCL.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... request for each end-user. Example: end-user XXX is to be “added” and end-user AAA is to be “changed” from... Blocks 1 and 19. In Block 21, cite the end-user requirement or condition (i.e., end-user XXX is requested...

  4. 78 FR 51176 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2013-0012] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army, (OAA-AAHS....regulations.gov as they are received without change, including any personal identifiers or contact information...

  5. 78 FR 63970 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2013-0034] Proposed Collection; Comment Request AGENCY: Office of the Administrative Assistant to the Secretary of the Army (OAA-RPA), DoD... they are received without change, including any personal identifiers or contact information. FOR...

  6. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... any changes to the previously-approved measurement and/or allocation procedures. Your application... and reflect the same degree of water saturation as in the gas volume. (8) When requested by the Regional Supervisor, submit copies of gas volume statements for each requested gas meter. Show whether gas...

  7. 77 FR 16870 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... take into account the frequency, volume, and duration of the employees' unemployment and sickness benefits. Each employer's contribution rate includes a component for administrative expenses as well as a... response is requested quarterly of each respondent and completion is mandatory. The RRB proposes no changes...

  8. 48 CFR 243.205-71 - Requests for equitable adjustment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requests for equitable adjustment. 243.205-71 Section 243.205-71 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.205-71...

  9. 77 FR 31005 - Agency Information Collection Activities; Proposed Collection; Comment Request; 2013 Hazardous...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... Activities; Proposed Collection; Comment Request; 2013 Hazardous Waste Report, Notification of Regulated Waste Activity, and Part A Hazardous Waste Permit Application and Modification AGENCY: Environmental... proposed changes to the Hazardous Waste Report form and instructions designed to clarify long-standing...

  10. Baseline estradiol concentration in community-dwelling Japanese American men is not associated with intra-abdominal fat accumulation over 10 years.

    PubMed

    Kocarnik, Beverly M; Boyko, Edward J; Matsumoto, Alvin M; Fujimoto, Wilfred Y; Hayashi, Tomoshige; Leonetti, Donna L; Page, Stephanie T

    The role of plasma estradiol in the accumulation of intra-abdominal fat (IAF) in men is uncertain. Cross-sectional studies using imaging of IAF have shown either a positive or no association. In contrast, a randomised controlled trial using an aromatase inhibitor to suppress estradiol production found an association between oestrogen deficiency and short-term IAF accumulation. No longitudinal study has been conducted to examine the relationship between plasma estradiol concentration and the change in IAF area measured using direct imaging. This is a longitudinal observational study in community-dwelling Japanese-American men (n=215, mean age 52 years, BMI 25.4kg/m 2 ). IAF and subcutaneous fat areas were assessed using computerized tomography (CT) at baseline, 5 and 10 years. Baseline plasma estradiol concentrations were measured using liquid chromatography-tandem mass spectrometry. Univariate analysis found no association between baseline estradiol concentration and baseline IAF, or 5- or 10-year changes in IAF area (r=-0.05 for both time points, p=0.45 and p=0.43, respectively). Multivariate linear regression analysis of the change in IAF area by baseline estradiol concentration adjusted for age, baseline IAF area, and weight change found no association with either the 5- or 10-year IAF area change (p=0.52 and p=0.55, respectively). Plasma estradiol concentration was not associated with baseline IAF nor with change in IAF area over 5 or 10 years based on serial CT scans in community-dwelling Japanese-American men. These results do not support a role for oestrogen deficiency in IAF accumulation in men. Copyright © 2015 Asia Oceania Association for the Study of Obesity. All rights reserved.

  11. Baseline estradiol concentration in community-dwelling Japanese American men is not associated with intra-abdominal fat accumulation over 10 years

    PubMed Central

    Kocarnik, Beverly M.; Boyko, Edward J.; Matsumoto, Alvin M.; Fujimoto, Wilfred Y.; Hayashi, Tomoshige; Leonetti, Donna L.; Page, Stephanie T.

    2016-01-01

    Summary Problem The role of plasma estradiol in the accumulation of intra-abdominal fat (IAF) in men is uncertain. Cross-sectional studies using imaging of IAF have shown either a positive or no association. In contrast, a randomised controlled trial using an aromatase inhibitor to suppress estradiol production found an association between oestrogen deficiency and short-term IAF accumulation. No longitudinal study has been conducted to examine the relationship between plasma estradiol concentration and the change in IAF area measured using direct imaging. Methods This is a longitudinal observational study in community-dwelling Japanese-American men (n = 215, mean age 52 years, BMI 25.4 kg/m2). IAF and subcutaneous fat areas were assessed using computerized tomography (CT) at baseline, 5 and 10 years. Baseline plasma estradiol concentrations were measured using liquid chromatography-tandem mass spectrometry. Results Univariate analysis found no association between baseline estradiol concentration and baseline IAF, or 5- or 10-year changes in IAF area (r = −0.05 for both time points, p = 0.45 and p = 0.43, respectively). Multivariate linear regression analysis of the change in IAF area by baseline estradiol concentration adjusted for age, baseline IAF area, and weight change found no association with either the 5- or 10-year IAF area change (p = 0.52 and p = 0.55, respectively). Conclusions Plasma estradiol concentration was not associated with baseline IAF nor with change in IAF area over 5 or 10 years based on serial CT scans in community-dwelling Japanese-American men. These results do not support a role for oestrogen deficiency in IAF accumulation in men. PMID:26747209

  12. Determination of Baseline Periods of Record for Selected Streamflow-Gaging Stations in New Jersey for Determining Ecologically Relevant Hydrologic Indices (ERHI)

    USGS Publications Warehouse

    Esralew, Rachel A.; Baker, Ronald J.

    2008-01-01

    Hydrologic changes in New Jersey stream basins resulting from human activity can affect the flow and ecology of the streams. To assess future changes in streamflow resulting from human activity an understanding of the natural variability of streamflow is needed. The natural variability can be classified using Ecologically Relevant Hydrologic Indices (ERHIs). ERHIs are defined as selected streamflow statistics that characterize elements of the flow regime that substantially affect biological health and ecological sustainability. ERHIs are used to quantitatively characterize aspects of the streamflow regime, including magnitude, duration, frequency, timing, and rate of change. Changes in ERHI values can occur as a result of human activity, and changes in ERHIs over time at various stream locations can provide information about the degree of alteration in aquatic ecosystems at or near those locations. New Jersey streams can be divided into four classes (A, B, C, or D), where streams with similar ERHI values (determined from cluster analysis) are assigned the same stream class. In order to detect and quantify changes in ERHIs at selected streamflow-gaging stations, a 'baseline' period is needed. Ideally, a baseline period is a period of continuous daily streamflow record at a gaging station where human activity along the contributing stream reach or in the stream's basin is minimal. Because substantial urbanization and other development had already occurred before continuous streamflow-gaging stations were installed, it is not possible to identify baseline periods that meet this criterion for many reaches in New Jersey. Therefore, the baseline period for a considerably altered basin can be defined as a period prior to a substantial human-induced change in the drainage basin or stream reach (such as regulations or diversions), or a period during which development did not change substantially. Index stations (stations with minimal urbanization) were defined as streamflow-gaging stations in basins that contain less than 15 percent urban land use throughout the period of continuous streamflow record. A minimum baseline period of record for each stream class was determined by comparing the variability of selected ERHIs among consecutive 5-, 10-, 15-, and 20-year time increments for index stations. On the basis of this analysis, stream classes A and D were assigned a minimum of 20 years of continuous record as a baseline period and stream classes B and C, a minimum of 10 years. Baseline periods were calculated for 85 streamflow-gaging stations in New Jersey with 10 or more years of continuous daily streamflow data, and the values of 171 ERHIs also were calculated for these baseline periods for each station. Baseline periods were determined by using historical streamflow-gaging station data, estimated changes in impervious surface in the drainage basin, and statistically significant changes in annual base flow and runoff. Historical records were reviewed to identify years during which regulation, diversions, or withdrawals occurred in the drainage basins. Such years were not included in baseline periods of record. For some sites, the baseline period of record was shorter than the minimum period of record specified for the given stream class. In such cases, the baseline period was rated as 'poor'. Impervious surface was used as an indicator of urbanization and change in streamflow characteristics owing to increases in storm runoff and decreases in base flow. Percentages of impervious surface were estimated for 85 streamflow-gaging stations from available municipal population-density data by using a regression model. Where the period of record was sufficiently long, all years after the impervious surface exceeded 10 to 20 percent were excluded from the baseline period. The percentage of impervious surface also was used as a criterion in assigning qualitative ratings to baseline periods. Changes in trends of annual base fl

  13. Role of baseline leptin and ghrelin levels on body weight and fat mass changes after an energy-restricted diet intervention in obese women: effects on energy metabolism.

    PubMed

    Labayen, Idoia; Ortega, Francisco B; Ruiz, Jonatan R; Lasa, Arrate; Simón, Edurne; Margareto, Javier

    2011-06-01

    Hormones related to energy balance control may play an important role on weight loss resistance after low-caloric diet (LCD) intervention. To investigate the predictive value of baseline leptin and ghrelin on body fat mass (FM) loss after 12 wk of LCD intervention and to study whether these associations could be related to changes in resting metabolic rate (RMR). The study comprised a total of 78 obese women (age 36.7 ± 7 yr). We measured, before and after the LCD intervention, FM (dual-energy x-ray absorptiometry) and RMR (kilojoules per kilogram body weight per day, indirect calorimetry). We also analyzed fasting serum leptin and ghrelin, and leptin to ghrelin ratio was calculated. FM and RMR changes (data at baseline - data after the intervention) were assessed. Baseline serum leptin (r = -0.301; age- and baseline FM-adjusted P = 0.009) and ghrelin (r = 0.314, adjusted P = 0.014) levels as well as leptin to ghrelin levels (r = -0.331; adjusted P = 0.009) were significantly correlated with FM changes. Leptin to ghrelin ratio was significantly correlated with RMR at baseline and after the LCD (both P < 0.010). Baseline leptin to ghrelin ratio significantly predicted changes in RMR after the LCD (r = 0.298; P = 0.019) regardless of age, baseline RMR, and total body weight (r = 0.307; P = 0.016) or FM loss (r = 0.312; P = 0.015). Obese women with higher leptin and lower ghrelin levels at baseline seem to be more resistant to FM loss. The leptin to ghrelin ratio could be proposed as a biomarker for predicting metabolic adaptations to energy restriction treatment and, if confirmed in future studies, as a predictor of treatment success/failure.

  14. 75 FR 70754 - Postal Classification Changes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... POSTAL REGULATORY COMMISSION [Docket No. MC2011-5; Order No. 583] Postal Classification Changes...-filed Postal Service request announcing a classification change affecting bundle and container charges... Commission announcing a classification change [[Page 70755

  15. 78 FR 43943 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... and Exchange Commission has submitted to the Office of Management and Budget a request for extension... investment advisory contract and the approval of changes in fundamental investment policies of the Fund... Affairs, Office of Management and Budget, Room 10102, New Executive Office Building, Washington, DC 20503...

  16. 78 FR 38293 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... of the U.S. Department of Commerce Office of Energy and Environmental Industries. It allows accurate... trade negotiation efforts. The title of the information collection has been changed to reflect the title...

  17. 76 FR 68194 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... Layouts for HPBS Work Measures. OMB No.: 0970-0230. Description: There is no longer a High Performance... information on States' performance. The Transmission File Layouts form provides the format that States will... are not requesting any changes to the Transmission File Layouts form. Respondents: Respondents may...

  18. 75 FR 62542 - Agency Information Collection Request. 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Public Health Service Act, as amended. The funding opportunity focuses on two categories of activities: Category A: Obesity prevention through improved nutrition and increased physical activity Category B.../enactment of MAPPS-related policy, systems, and environmental change in physical activity, nutrition, and...

  19. 77 FR 57197 - Proposed Collection; Comment Request for Form 1099-CAP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... 1099-CAP AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments... Form 1099-CAP, Changes in Corporate Control and Capital Structure. DATES: Written comments should be... Structure. OMB Number: 1545-1814. Form Number: 1099-CAP. Abstract: Any corporation that undergoes...

  20. 77 FR 31857 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... OMB Review; Comment Request Title: 1309 Head Start Facilities Construction, Purchase and Major Renovations. OMB No.: 0970-0193. Description: The Head Start Bureau is proposing to renew, without changes... administrative requirements applicable to Head Start and Early Head Start grantees, when applying for funding to...

  1. 48 CFR 243.204-71 - Certification of requests for equitable adjustment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Certification of requests for equitable adjustment. 243.204-71 Section 243.204-71 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders...

  2. 77 FR 75407 - Proposed Information Collection; Comment Request; Interim Procedures for Considering Requests...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... States-Panama Trade Promotion Agreement Implementation Act (the ``Act'') [Pub. L. 112-43] implements the... Promotion Agreement (the ``Agreement''). This safeguard mechanism applies when, as a result of the...) all data available to the requestor showing changes in productivity, utilization of capacity...

  3. 77 FR 33226 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... Pricing Program while maintaining efficiency, transparency and integrity, the HRSA Office of Pharmacy... minimal for submitting change requests. Contract Pharmacy Self-Certification In order to ensure that drug manufacturers and drug wholesalers recognize contract pharmacy arrangements, covered entities that elect to...

  4. 78 FR 75926 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-13

    ... Geographic Classification Review Board (MGCRB) in reviewing and making decisions regarding hospitals... the following transmissions: OMB, Office of Information and Regulatory Affairs, Attention: CMS Desk... Deborah Larwood at 410-786-9500). 2. Type of Information Collection Request: Extension without change of a...

  5. Request for Correction 12001 Analyses Associated with the Impact of Biofuels

    EPA Pesticide Factsheets

    Request for Correction #11001 by the Competitive Enterprise Institute and ActionAid USA regarding the impacts of biofuel mandates on global hunger and mortality in the EPA's Regulation of Fuels and Fuel Additives: Changes to Renewable Fuel Standard Program, 40 CFR Part 80.

  6. 78 FR 5780 - Agency Information Collection Activities: Proposed Collection, Comment Request: Generic Clearance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... could change significantly based on the collection method ultimately used in the research. Estimated..., Comment Request: Generic Clearance for the Collection of Qualitative Feedback on Agency Service Delivery... qualitative consumer and stakeholder feedback in an efficient, timely manner to facilitate service delivery...

  7. 77 FR 36294 - Agency Information Collection Activities; Proposed Collection; Comments Requested: Accounting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... Collection Activities; Proposed Collection; Comments Requested: Accounting System and Financial Capability... change of a currently approved collection. (2) The title of the form/collection: Accounting System and... for-profit entities and not-for-profit institutions. Other: None. The purpose of the Accounting System...

  8. 48 CFR 243.204-71 - Certification of requests for equitable adjustment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Certification of requests for equitable adjustment. 243.204-71 Section 243.204-71 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders...

  9. Improving the care pathway for women who request Caesarean section: an experience-based co-design study.

    PubMed

    Kenyon, Sara L; Johns, Nina; Duggal, Sandhya; Hewston, Ruth; Gale, Nicola

    2016-11-09

    Maternal request for Caesarean section is controversial and yet the NICE Caesarean section Guideline recommends that that if this is requested, following discussion of the risks and benefits, women should be supported in their choice. There was a desire to improve the pathway at Birmingham Women's NHS Foundation Trust. Experience-based co-design methodology uses service user and clinicians experiences collected using qualitative methods to jointly re-design services. Firstly semi-structured interviews were conducted to elicit the views and experiences of health care professionals and women who requested Caesarean section (with and without medical indication). Analysis identified key themes arising from the health care professionals' interviews and 'touch points' (key moments or events related to the experience of care) arising from the interviews with women.. Separate workshops were then held with each group to ensure these resonated and to identify key areas for service improvement. At the first joint workshop a pathway using 'audio clips' demonstrating women's agreed 'touch points' prompted discussion and joint working began to change the pathway. A final second workshop was held to agree changes to the pathway. Interviews were conducted with health care professionals (n = 22, 10 consultant obstetricians and 12 midwives) and women (n = 15). The women's 'touch points' included repetition of request, delay in the decision for Caesarean section to be made, feeling judged, and that information was poor with similar findings identified from the health care professionals. Joint working resulted in a revised pathway for women who request Caesarean section. Changes to the pathway for women as a result of the work include written information about 'The way your baby may be born' which is given to the woman followed by a discussion about mode of birth around the 16 week appointment. If the woman wishes to have a Caesarean section, referral is made to appropriate health care professionals (e.g., Consultant Midwife, counsellor) only if support and information would be useful. If Caesarean section is requested, woman is referred to a consultant obstetrician for an appointment at 20/40, with a decision by 28/40. Recording this in the notes minimises repeated challenge described by women. Final consent and timing of Caesarean section remain as recommended. This has resulted in changes to the pathway agreed by a co-design process and which are acceptable to both health care professionals and women. Use of such methodologies should be considered more frequently when implementing service change.

  10. Increased Visceral Adipose Tissue Is an Independent Predictor for Future Development of Atherogenic Dyslipidemia.

    PubMed

    Hwang, You-Cheol; Fujimoto, Wilfred Y; Hayashi, Tomoshige; Kahn, Steven E; Leonetti, Donna L; Boyko, Edward J

    2016-02-01

    Atherogenic dyslipidemia is frequently observed in persons with a greater amount of visceral adipose tissue (VAT). However, it is still uncertain whether VAT is independently associated with the future development of atherogenic dyslipidemia. The aim of this study was to determine whether baseline and changes in VAT and subcutaneous adipose tissue (SAT) are associated with future development of atherogenic dyslipidemia independent of baseline lipid levels and standard anthropometric indices. Community-based prospective cohort study with 5 years of follow-up. A total of 452 Japanese Americans (240 men, 212 women), aged 34-75 years were assessed at baseline and after 5 years of follow-up. Abdominal fat areas were measured by computed tomography. Atherogenic dyslipidemia was defined as one or more abnormalities in high-density lipoprotein (HDL) cholesterol, triglycerides, or non-HDL cholesterol levels. Baseline VAT and change in VAT over 5 years were independently associated with log-transformed HDL cholesterol, log-transformed triglyceride, and non-HDL cholesterol after 5 years (standardized β = -0.126, 0.277, and 0.066 for baseline VAT, respectively, and -0.095, 0.223, and 0.090 for change in VAT, respectively). However, baseline and change in SAT were not associated with any future atherogenic lipid level. In multivariate logistic regression analysis, incremental change in VAT (odds ratio [95% confidence interval], 1.73 [1.20-2.48]; P = .003), triglycerides (4.01 [1.72-9.33]; P = .001), HDL cholesterol (0.32 [0.18-0.58]; P < .001), and non-HDL cholesterol (7.58 [4.43-12.95]; P < .001) were significantly associated with the future development of atherogenic dyslipidemia independent of age, sex, diastolic blood pressure, homeostasis model assessment insulin resistance, body mass index (BMI), change in BMI, SAT, and baseline atherogenic lipid levels. Baseline and change in VAT were independent predictors for future development of atherogenic dyslipidemia. However, BMI, waist circumference, and SAT were not associated with future development of atherogenic dyslipidemia.

  11. Conservation of forest birds: evidence of a shifting baseline in community structure

    Treesearch

    Chadwick D. Rittenhouse; Anna M. Pidgeon; Thomas P. Albright; Patrick D. Culbert; Murray K. Clayton; Curtis H. Flather; Chengquan Huang; Jeffrey G. Masek; Susan I. Stewart; Volker C. Radeloff

    2010-01-01

    Quantifying changes in forest bird diversity is an essential task for developing effective conservation actions. When subtle changes in diversity accumulate over time, annual comparisons may offer an incomplete perspective of changes in diversity. In this case, progressive change, the comparison of changes in diversity from a baseline condition, may offer greater...

  12. Ghrelin and PYY levels in adolescents with severe obesity: effects of weight loss induced by long-term exercise training and modified food habits.

    PubMed

    Gueugnon, Carine; Mougin, Fabienne; Nguyen, Nhu Uyen; Bouhaddi, Malika; Nicolet-Guénat, Marie; Dumoulin, Gilles

    2012-05-01

    This study investigated (a) changes in ghrelin and peptide YY (PYY) concentrations during a weight reduction programme and (b) baseline ghrelin and PYY levels as predictors of weight loss in 32 severely obese adolescents (BMI z score = 4.1). Subjects spent an academic year in an institution for childhood obesity. Fasting ghrelin and PYY, leptin, insulin levels and insulin resistance were measured at baseline (month 0) and during the programme (months 3, 6, 9). In addition, 15 normal-weight teenagers served as reference for the baseline assessments. At baseline, obese teenagers had lower ghrelin and PYY concentrations than normal-weight adolescents (P < 0.05). Moreover, they showed significantly higher leptin, insulin levels and homeostasis model assessment (HOMA) (P < 0.0001). During the lifestyle modification, there was a significant decrease in body weight among obese teenagers, associated with an increase in ghrelin (apparent from month 6; P < 0.05), a decrease in leptin (from month 3; P < 0.05) and a decrease in insulin and HOMA (from month 3; P < 0.0001), without any significant change in PYY. Anthropometrical changes were correlated neither with baseline ghrelin levels nor with changes in ghrelin and PYY after the lifestyle modification. However, higher baseline PYY tended to correlate with greater anthropometrical changes (P < 0.1). In adolescents with severe obesity, a long-term combination of supervised aerobic exercises and a balanced diet led to weight reduction and increased ghrelin concentrations, without any change in PYY concentrations. Moreover, baseline PYY concentrations might be considered as predictors of weight loss.

  13. Baseline and changes in serum uric acid independently predict 11-year incidence of metabolic syndrome among community-dwelling women.

    PubMed

    Kawamoto, R; Ninomiya, D; Kasai, Y; Senzaki, K; Kusunoki, T; Ohtsuka, N; Kumagi, T

    2018-02-19

    Metabolic syndrome (MetS) is associated with an increased risk of major cardiovascular events. In women, increased serum uric acid (SUA) levels are associated with MetS and its components. However, whether baseline and changes in SUA predict incidence of MetS and its components remains unclear. The subjects comprised 407 women aged 71 ± 8 years from a rural village. We have identified participants who underwent a similar examination 11 years ago, and examined the relationship between baseline and changes in SUA, and MetS based on the modified criteria of the National Cholesterol Education Program's Adult Treatment Panel (NCEP-ATP) III report. Of these subjects, 83 (20.4%) women at baseline and 190 (46.7%) women at follow-up had MetS. Multiple linear regression analysis was performed to evaluate the contribution of each confounding factor for MetS; both baseline and changes in SUA as well as history of cardiovascular disease, low-density lipoprotein cholesterol, and estimated glomerular filtration ratio (eGFR) were independently and significantly associated with the number of MetS components during an 11-year follow-up. The adjusted odds ratios (ORs) (95% confidence interval) for incident MetS across tertiles of baseline SUA and changes in SUA were 1.00, 1.47 (0.82-2.65), and 3.11 (1.66-5.83), and 1.00, 1.88 (1.03-3.40), and 2.49 (1.38-4.47), respectively. In addition, the combined effect between increased baseline and changes in SUA was also a significant and independent determinant for the accumulation of MetS components (F = 20.29, p < 0.001). The ORs for incident MetS were significant only in subjects with age ≥ 55 years, decline in eGFR, and no baseline MetS. These results suggested that combined assessment of baseline and changes in SUA levels provides increased information for incident MetS, independent of other confounding factors in community-dwelling women.

  14. Changes in sexual function in middle-aged and older men: longitudinal data from the Massachusetts Male Aging Study.

    PubMed

    Araujo, Andre B; Mohr, Beth A; McKinlay, John B

    2004-09-01

    To describe within-individual change in sexual function over a 9-year period and to determine whether the amount of change differs by age group. Cohort study; participants interviewed at baseline (1987-89) and follow-up (1995-97). Population-based; communities surrounding Boston, Massachusetts. One thousand eighty-five men aged 40 to 70 at baseline (born between 1917 and 1947) with complete baseline and follow-up sexual function data. Within-person change (follow-up minus baseline) in the following sexual function variables: sexual intercourse, erection frequency, sexual desire, ejaculation with masturbation, satisfaction with sex, and difficulty with orgasm. Unadjusted analyses showed significant longitudinal changes over the 9-year period in all domains of sexual function except frequency of ejaculation with masturbation, which showed no change between baseline and follow-up. Adjusted for baseline sexual function, within-person change in all outcomes was strongly related to age, with decline in sexual function becoming more pronounced with increasing age. For example, over the 9-year study period, sexual intercourse or activity frequency decreased by less than once per month, two times per month, and three times per month in men in their 40s, 50s, and 60s, respectively. Number of erections per month declined by 3, 9, and 13 in men in their 40s, 50s, and 60s, respectively. This research fills a major gap in the literature by providing age-specific estimates of change in sexual functioning over a 9-year period in a cohort of unselected men. Copyright 2004 American Geriatrics Society

  15. 76 FR 77813 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

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  16. 75 FR 71416 - Submission for OMB Review; Comment Request

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  17. 78 FR 53793 - Request To Amend a License To Export Radioactive Waste

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  18. 48 CFR 5242.9000 - Requests for refunds.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... intrinsic value as defined in the clause at 5252.242-9000. Refunds shall be requested only for the difference between the intrinsic value of the item at the time an agreement on price was reached and the... due to productivity gains (beyond economic quantity considerations) or changes in market conditions...

  19. 48 CFR 5242.9000 - Requests for refunds.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... intrinsic value as defined in the clause at 5252.242-9000. Refunds shall be requested only for the difference between the intrinsic value of the item at the time an agreement on price was reached and the... due to productivity gains (beyond economic quantity considerations) or changes in market conditions...

  20. 48 CFR 5242.9000 - Requests for refunds.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... intrinsic value as defined in the clause at 5252.242-9000. Refunds shall be requested only for the difference between the intrinsic value of the item at the time an agreement on price was reached and the... due to productivity gains (beyond economic quantity considerations) or changes in market conditions...

  1. 48 CFR 5242.9000 - Requests for refunds.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... intrinsic value as defined in the clause at 5252.242-9000. Refunds shall be requested only for the difference between the intrinsic value of the item at the time an agreement on price was reached and the... due to productivity gains (beyond economic quantity considerations) or changes in market conditions...

  2. 78 FR 7436 - Request for Public Comment: 30-Day Proposed Information Collection: Indian Health Service...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ..., 0917- 0002, ``IHS Contract Health Service Report.'' While there were minor text changes (i.e., updating... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service Request for Public Comment: 30-Day Proposed Information Collection: Indian Health Service Contract Health Services Report AGENCY: Indian...

  3. 75 FR 79438 - Notice of Request for the Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

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  4. 76 FR 54242 - Agency Information Collection Activities: Post-Award Contract Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Information AGENCY: Office of Chief Procurement Officer, DHS. ACTION: 60-Day notice and request for comments; Extension without change. SUMMARY: The Department of Homeland Security, Office of Chief Procurement Officer... about this Information Collection Request should be forwarded to the Office of Chief Procurement Officer...

  5. 22 CFR 505.7 - Correction or amendment of record.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 505.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PRIVACY ACT REGULATION § 505.7 Correction or... be in writing and mailed or delivered to the FOIA/Privacy Act Officer, FOIA/Privacy Act Office... requested change. The requester should submit as much documentation, arguments or other data as seems...

  6. 22 CFR 505.7 - Correction or amendment of record.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 505.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PRIVACY ACT REGULATION § 505.7 Correction or... be in writing and mailed or delivered to the FOIA/Privacy Act Officer, FOIA/Privacy Act Office... requested change. The requester should submit as much documentation, arguments or other data as seems...

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    ... Collection for the Workforce Investment Act (WIA) Management Information and Reporting System; Extension With... changes that are being requested in the extension with revisions to the WIA Management Information and.... III. Current Actions Type of Review: Extension with revisions. Title: WIA Management Information and...

  8. 78 FR 48138 - Proposed Information Collection; Comment Request; Report of Requests for Restrictive Trade...

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  9. 77 FR 50677 - Submission for OMB Review; Comment Request

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    2012-08-22

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... the benefits and costs of changes in management measures, and to monitor and respond to incidental..., Department of Commerce, Room 6616, 14th and Constitution Avenue NW., Washington, DC 20230 (or via the...

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    2012-03-28

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  11. 75 FR 5945 - Proposed Information Collection; Comment Request; Pacific Coast Groundfish, Rationalization...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... Activities; Proposed Collection; Comment Request; Reporting Under EPA's Landfill Methane Outreach Program...; and other landfill gas energy stakeholders. Title: Reporting Under EPA's Landfill Methane Outreach... Landfill Methane Outreach Program (LMOP), created by EPA as part of the Climate Change Action Plan, is a...

  13. 77 FR 65366 - Interim Procedures for Considering Requests From the Public for Textile and Apparel Safeguard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... Promotion Agreement (``U.S.-Colombia TPA''). Title III, Subtitle B, Section 321 through Section 328 of the United States-Colombia Trade Promotion Agreement Implementation Act (``Implementation Act'') [Pub. L. 112... requester showing changes in productivity, utilization of capacity, inventories, exports, wages, employment...

  14. 19 CFR 177.2 - Submission of ruling requests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Headquarters Office will prepare final decisions under § 177.11 (Requests for Advice by Field Officers), or § 174.23 (Further Review of Protests), § 177.10 (Change of Practice), decisions under part 175 of this... Carrier rulings should be addressed to the Commissioner of Customs and Border Protection, Attention...

  15. 15 CFR Appendix A to Subpart C of... - Certification Application Templates

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Contact E-Mail Address This is a request for the above named company or individual (hereinafter referred... Distributor prior to submitting the application. (1) Correspondence and applications/requests for... contact (995.10 (d)). Distributor agrees to immediately notify the Government of any changes to point of...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... determination to complete Form SSA-3441-BK. This form allows claimants to disclose any changes to their disability or resources that might influence SSA's unfavorable determination. SSA may use the information to: (1) Reconsider and review an initial disability determination; (2) review a continuing disability...

  18. 18 CFR 341.14 - Special permission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requested waiver. If the application requests permission to make changes in joint tariffs, it must state... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Special permission. 341... COMPANIES SUBJECT TO SECTION 6 OF THE INTERSTATE COMMERCE ACT § 341.14 Special permission. (a) Procedure...

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    ... request the consent of the Commissioner to change their methods of accounting for the capitalization of... number. Books or records relating to a collection of information must be retained as long as their... information is necessary for the proper performance of the functions of the agency, including whether the...

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  7. 7 CFR 945.80 - Reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Reports. 945.80 Section 945.80 Agriculture Regulations... Reports. (a) Upon the request of the committee, with approval of the Secretary, every handler shall... shall have the right to modify, change, or rescind any requests for reports pursuant to this section. (b...

  8. 7 CFR 945.80 - Reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Reports. 945.80 Section 945.80 Agriculture Regulations... Reports. (a) Upon the request of the committee, with approval of the Secretary, every handler shall... shall have the right to modify, change, or rescind any requests for reports pursuant to this section. (b...

  9. 32 CFR 312.7 - Request for correction or amendment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Request for correction or amendment. 312.7 Section 312.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE... be changed as specifically as possible, the type of amendment (e.g., deletion, correction, amendment...

  10. 32 CFR 312.7 - Request for correction or amendment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Request for correction or amendment. 312.7 Section 312.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE... be changed as specifically as possible, the type of amendment (e.g., deletion, correction, amendment...

  11. 32 CFR 312.7 - Request for correction or amendment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Request for correction or amendment. 312.7 Section 312.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE... be changed as specifically as possible, the type of amendment (e.g., deletion, correction, amendment...

  12. 32 CFR 312.7 - Request for correction or amendment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Request for correction or amendment. 312.7 Section 312.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE... be changed as specifically as possible, the type of amendment (e.g., deletion, correction, amendment...

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  16. Modelling fluid accumulation in the neck using simple baseline fluid metrics: implications for sleep apnea.

    PubMed

    Vena, Daniel; Yadollahi, A; Bradley, T Douglas

    2014-01-01

    Obstructive sleep apnea (OSA) is a common respiratory disorder among adults. Recently we have shown that sedentary lifestyle causes an increase in diurnal leg fluid volume (LFV), which can shift into the neck at night when lying down to sleep and increase OSA severity. The purpose of this work was to investigate various metrics that represent baseline fluid retention in the legs and examine their correlation with neck fluid volume (NFV) and to develop a robust model for predicting fluid accumulation in the neck. In 13 healthy awake non-obese men, LFV and NFV were recorded continuously and simultaneously while standing for 5 minutes and then lying supine for 90 minutes. Simple regression was used to examine correlations between baseline LFV, baseline neck circumference (NC) and change in LFV with the outcome variables: change in NC (ΔNC) and in NFV (ΔNFV90) after lying supine for 90 minutes. An exhaustive grid search was implemented to find combinations of input variables which best modeled outcomes. We found strong positive correlations between baseline LFV (supine and standing) and ΔNFV90. Models developed for predicting ΔNFV90 included baseline standing LFV, baseline NC combined with change in LFV after lying supine for 90 minutes. These correlations and the developed models suggest that a greater baseline LFV might contribute to increased fluid accumulation in the neck. These results give more evidence that sedentary lifestyle might play a role in the pathogenesis of OSA by increasing the baseline LFV. The best models for predicting ΔNC include baseline LFV and NC; they improved accuracies of estimating ΔNC over individual predictors, suggesting that a combination of baseline fluid metrics is a good predictor of the change in NC while lying supine. Future work is aimed at adding additional baseline demographic features to improve model accuracy and eventually use it as a screening tool to predict severity of OSA prior to sleep.

  17. An Ontology for Requesting Distant Robotic Action: A Case Study in Naming and Action Identification for Planning on the Mars Exploration Rover Mission

    NASA Technical Reports Server (NTRS)

    Wales, Roxana C.; Shalin, Valerie L.; Bass, Deborah S.

    2004-01-01

    This paper focuses on the development and use of the abbreviated names as well as an emergent ontology associated with making requests for action of a distant robotic rover during the 2003-2004 NASA Mars Exploration Rover (MER) mission, run by the Jet Propulsion Laboratory. The infancy of the domain of Martian telerobotic science, in which specialists request work from a rover moving through the landscape, as well as the need to consider the interdisciplinary teams involved in the work required an empirical approach. The formulation of this ontology is grounded in human behavior and work practice. The purpose of this paper is to identify general issues for an ontology of action (specifically for requests for action), while maintaining sensitivity to the users, tools and the work system within a specific technical domain. We found that this ontology of action must take into account a dynamic environment, changing in response to the movement of the rover, changes on the rover itself, as well as be responsive to the purposeful intent of the science requestors. Analysis of MER mission events demonstrates that the work practice and even robotic tool usage changes over time. Therefore, an ontology must adapt and represent both incremental change and revolutionary change, and the ontology can never be more than a partial agreement on the conceptualizations involved. Although examined in a rather unique technical domain, the general issues pertain to the control of any complex, distributed work system as well as the archival record of its accomplishments.

  18. Meta-Analysis of the Relation of Baseline Right Ventricular Function to Response to Cardiac Resynchronization Therapy.

    PubMed

    Sharma, Abhishek; Bax, Jerome J; Vallakati, Ajay; Goel, Sunny; Lavie, Carl J; Kassotis, John; Mukherjee, Debabrata; Einstein, Andrew; Warrier, Nikhil; Lazar, Jason M

    2016-04-15

    Right ventricular (RV) dysfunction has been associated with adverse clinical outcomes in patients with heart failure (HF). Cardiac resynchronization therapy (CRT) improves left ventricular (LV) size and function in patients with markedly abnormal electrocardiogram QRS duration. However, relation of baseline RV function with response to CRT has not been well described. In this study, we aim to investigate the relation of baseline RV function with response to CRT as assessed by change in LV ejection fraction (EF). A systematic search of studies published from 1966 to May 31, 2015 was conducted using PubMed, CINAHL, Cochrane CENTRAL, and the Web of Science databases. Studies were included if they have reported (1) parameters of baseline RV function (tricuspid annular plane systolic excursion [TAPSE] or RVEF or RV basal strain or RV fractional area change [FAC]) and (2) LVEF before and after CRT. Random-effects metaregression was used to evaluate the effect of baseline RV function parameters and change in LVEF. Sixteen studies (n = 1,764) were selected for final analysis. Random-effects metaregression analysis showed no significant association between the magnitude of the difference in EF before and after CRT with baseline TAPSE (β = 0.005, p = 0.989); baseline RVEF (β = 0.270, p = 0.493); baseline RVFAC (β = -0.367, p = 0.06); baseline basal strain (β = -0.342, p = 0.462) after a mean follow-up period of 10.5 months. In conclusion, baseline RV function as assessed by TAPSE, FAC, basal strain, or RVEF does not determine response to CRT as assessed by change in LVEF. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Satellite laser ranging and geological constraints on plate motion

    NASA Technical Reports Server (NTRS)

    Harrison, C. G. A.; Douglas, Nancy B.

    1990-01-01

    Satellite laser ranging (SLR) observed baseline rates of change were measured and compared with rates determined from sea floor spreading rates and directions, and earth-quake solutions. With the number of years of observation now over six for many of the baselines, the inaccuracy of determining baseline rates of change has diminished so that in some cases it is less than a few mm per year. Thus, a direct comparison between baseline rates of change and rates of change established using geophysical information (called geological rates) is now feasible. In most cases, there is good agreement between the rates determined from SLR and geological rates, but in some cases there appear to be discrepancies. These discrepancies involve many of the data for which one end of the baseline is either Quincy (California), Huahine (French Polynesia), or Simosato (Japan). A method for looking at the discrepancies for these SLR observatories has been devised which makes it possible to calculate the motion not modeled by the geologic information.

  20. Audit of Trichomonas vaginalis test requesting by community referrers after a change from culture to molecular testing, including a cost analysis.

    PubMed

    Bissessor, Liselle; Wilson, Janet; McAuliffe, Gary; Upton, Arlo

    2017-06-16

    Trichomonas vaginalis (TV) prevalence varies among different communities and peoples. The availability of robust molecular platforms for the detection of TV has advanced diagnosis; however, molecular tests are more costly than phenotypic methodologies, and testing all urogenital samples is costly. We recently replaced culture methods with the Aptima Trichomonas vaginalis nucleic acid amplification test on specific request and as reflex testing by the laboratory, and have audited this change. Data were collected from August 2015 (microbroth culture and microscopy) and August 2016 (Aptima TV assay) including referrer, testing volumes, results and test cost estimates. In August 2015, 10,299 vaginal swabs, and in August 2016, 2,189 specimens (urogenital swabs and urines), were tested. The positivity rate went from 0.9% to 5.3%, and overall more TV infections were detected in 2016. The number needed to test and cost for one positive TV result respectively was 111 and $902.55 in 2015, and 19 and $368.92 in 2016. Request volumes and positivity rates differed among referrers. The methodology change was associated with higher overall detection of TV, and reductions in the numbers needed to test/cost for one TV diagnosis. Our audit suggests that there is room for improvement with TV test requesting in our community.

  1. Longitudinal change instead of baseline testosterone predicts depressive symptoms.

    PubMed

    Kische, Hanna; Pieper, Lars; Venz, John; Klotsche, Jens; März, Winfried; Koch-Gromus, Uwe; Pittrow, David; Lehnert, Hendrik; Silber, Sigmund; Stalla, G K; Zeiher, Andreas M; Wittchen, Hans-Ulrich; Haring, Robin

    2018-03-01

    The association between total testosterone (T) and depression mostly relies on single sex hormone assessment and remains inconclusive. Thus, we investigated the comparative predictive performance of baseline T and change in T with development of depressive symptoms and incident depressive episodes. We used data from 6493 primary care patients (2653 men and 3840 women) of the DETECT study (Diabetes Cardiovascular Risk-Evaluation: Targets and Essential Data for Commitment of Treatment), including four-year follow-up, repeated immunoassay-based measurement of serum T and depressive symptoms assessed by the Depression Screening Questionnaire (DSQ). Cross-sectional and longitudinal associations of baseline T and one-year change in T with prevalent and incident depression were investigated using age- and multivariable-adjusted regression models. Baseline T showed no association with prevalent or incident depressive symptoms and episodes in both sexes. In men, a positive change in T (higher T at one-year follow-up compared to baseline) was associated with a lower burden of depressive symptoms (β-coefficient per unit change in T: -0.17; 95% CI: -0.31 to -0.04) and lower risk of incident depressive symptoms (odds ratio per unit change in T: 0.84; 95% CI: 0.72-0.98) at four-year follow-up. In women, the association of T change with incident depressive episodes was rendered non-significant after multivariable adjustment. The present study observed a sex-specific inverse association of T change, but not baseline T, with increased depressive symptom burden in men. Future studies should assess longitudinal changes in sex hormone status as predictor of adverse health outcomes related to low T. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Traffic Aware Planner for Cockpit-Based Trajectory Optimization

    NASA Technical Reports Server (NTRS)

    Woods, Sharon E.; Vivona, Robert A.; Henderson, Jeffrey; Wing, David J.; Burke, Kelly A.

    2016-01-01

    The Traffic Aware Planner (TAP) software application is a cockpit-based advisory tool designed to be hosted on an Electronic Flight Bag and to enable and test the NASA concept of Traffic Aware Strategic Aircrew Requests (TASAR). The TASAR concept provides pilots with optimized route changes (including altitude) that reduce fuel burn and/or flight time, avoid interactions with known traffic, weather and restricted airspace, and may be used by the pilots to request a route and/or altitude change from Air Traffic Control. Developed using an iterative process, TAP's latest improvements include human-machine interface design upgrades and added functionality based on the results of human-in-the-loop simulation experiments and flight trials. Architectural improvements have been implemented to prepare the system for operational-use trials with partner commercial airlines. Future iterations will enhance coordination with airline dispatch and add functionality to improve the acceptability of TAP-generated route-change requests to pilots, dispatchers, and air traffic controllers.

  3. Numeric score-based conditional and overall change-in-status indices for ordered categorical data.

    PubMed

    Lyles, Robert H; Kupper, Lawrence L; Barnhart, Huiman X; Martin, Sandra L

    2015-11-30

    Planned interventions and/or natural conditions often effect change on an ordinal categorical outcome (e.g., symptom severity). In such scenarios, it is sometimes desirable to assign a priori scores to observed changes in status, typically giving higher weight to changes of greater magnitude. We define change indices for such data based upon a multinomial model for each row of a c × c table, where the rows represent the baseline status categories. We distinguish an index designed to assess conditional changes within each baseline category from two others designed to capture overall change. One of these overall indices measures expected change across a target population. The other is scaled to capture the proportion of total possible change in the direction indicated by the data, so that it ranges from -1 (when all subjects finish in the least favorable category) to +1 (when all finish in the most favorable category). The conditional assessment of change can be informative regardless of how subjects are sampled into the baseline categories. In contrast, the overall indices become relevant when subjects are randomly sampled at baseline from the target population of interest, or when the investigator is able to make certain assumptions about the baseline status distribution in that population. We use a Dirichlet-multinomial model to obtain Bayesian credible intervals for the conditional change index that exhibit favorable small-sample frequentist properties. Simulation studies illustrate the methods, and we apply them to examples involving changes in ordinal responses for studies of sleep deprivation and activities of daily living. Copyright © 2015 John Wiley & Sons, Ltd.

  4. When the topic is you: genetic counselor responses to prenatal patients' requests for self-disclosure.

    PubMed

    Balcom, Jessica R; Veach, Patricia McCarthy; Bemmels, Heather; Redlinger-Grosse, Krista; LeRoy, Bonnie S

    2013-06-01

    A limited amount of research indicates patient requests play a major role in genetic counselors' self-disclosure decisions and that disclosure and non-disclosure responses to patient requests may differentially affect genetic counseling processes. Studies further suggest patient requests may be more common in prenatal settings, particularly when counselors are pregnant. Empirical evidence is limited however, concerning the nature of patient requests. This study explored genetic counselors' experiences of prenatal patients' requests for self-disclosure. Four major research questions were: (1) What types of questions do prenatal patients ask that invite self-disclosure?; (2) Do pregnant genetic counselors have unique experiences with prenatal patient disclosure requests?; (3) How do genetic counselors typically respond to disclosure requests?; and (4) What strategies are effective and ineffective in responding to disclosure requests? One hundred seventy-six genetic counselors completed an online survey and 40 also participated in telephone interviews. Inductive analysis of 21 interviews revealed patient questions vary, although questions about counselor demographics are most common, and patients are more likely to ask pregnant counselors questions about their personal pregnancy decisions. Participants reported greater discomfort with self-disclosure requests during pregnancy, yet also disclosing more frequently during pregnancy. Counselor responses included personal self-disclosure, professional self-disclosure, redirection, and declining to disclose. Factors perceived as influencing disclosure included: topic, patient motivations, timing of request, quality of counseling relationship, patient characteristics, and ethical/legal responsibilities. Disclosure practices changed over time for most counselors. Additional findings, practice implications, and research recommendations are discussed.

  5. Open access to MRI for general practitioners: 12 years' experience at one institution -- a retrospective analysis.

    PubMed

    Gough-Palmer, A L; Burnett, C; Gedroyc, W M

    2009-08-01

    The aim of this study was to evaluate 12 years of general practitioner (GP) use of open access MRI services at a single London teaching hospital. A retrospective analysis of reports from all GP requests for MRI scans between 1994 and 2005 was performed. The date, scanned body part, and requester details from 1798 scans requested by 209 individual GPs over a continuous 12-year period were recorded. All scans were then graded into four categories based on the severity of reported findings from normal to gross abnormality. Over the study period, GP requests as a percentage of the total (MRI) department workload remained low at approximately 2.6%. Spine, knee and brain requests constituted 86% (n = 1546) of requested scans. 48% (n = 868) of scans were reported as normal or minor degenerative changes only. 26% (n = 466) of scans demonstrated serious pathology that was likely to warrant hospital consultant referral. There was a wide range of scans requested per requester, from 1 to 240 over the period, with an average of 8.5 scans per GP. In conclusion, any department wishing to set up open access to MRI services for GPs could cover the majority of requests by offering spine, knee and brain imaging. The percentage of normal report rates for GP requests is comparable with previous studies of outpatient referrals. A large variation in requesting patterns between GPs suggests the need for increased communication between GPs and imaging departments to optimise use of the service.

  6. 20 CFR 405.317 - Objections.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... requesting the change and the impact of the proposed change on the efficient administration of the hearing process. Factors affecting the impact of the change include, but are not limited to, the effect on the...

  7. A mixed-method examination of food marketing directed towards children in Australian supermarkets.

    PubMed

    Campbell, Sarah; James, Erica L; Stacey, Fiona G; Bowman, Jennifer; Chapman, Kathy; Kelly, Bridget

    2014-06-01

    The purpose of this study was to determine the prevalence of children's food requests, and parents' experiences of food marketing directed towards children, in the supermarket environment. A mixed-method design was used. Firstly, intercept interviews were conducted with parents accompanied by a child/children on exiting supermarkets (sampled from a large regional centre in Australia). Parents were asked about the prevalence and types of food requests by child/children during their supermarket visit and whether they purchased these foods. Secondly, focus groups (n = 13) and telephone interviews (n = 3) were conducted exploring parents' experiences of supermarket shopping with children and the impact of child-directed marketing. Of the 158 intercept survey participants (30% response rate), 73% reported a food request during the supermarket visit. Most requested food items (88%) were unhealthy foods, with chocolate/confectionery being the most common food category requested (40%). Most parents (70%) purchased at least one food item requested during the shopping trip. Qualitative interviews identified four themes associated with food requests and prompts in the supermarket: parents' experience of pester power in the supermarket; prompts for food requests in the supermarket; parental responses to pestering in the supermarket environment, and; strategies to manage pestering and minimize requests for food items. Food requests from children are common during supermarket shopping. Despite the majority of the requests being unhealthy, parents often purchase these foods. Parents reported difficulties dealing with constant requests and expressed desire for environmental changes including confectionery-free checkouts, minimization of child friendly product placement and reducing children's exposure to food marketing.

  8. Monosodium glutamate and aspartame in perceived pain in fibromyalgia.

    PubMed

    Vellisca, María Y; Latorre, José I

    2014-07-01

    Our aim was to assess the effect of dietary elimination of monosodium glutamate (MSG) and aspartame on perceived pain in fibromyalgia. A total of 72 female patients with fibromyalgia were randomized to discontinuation of dietary MSG and aspartame (n = 36) or waiting list (n = 36). Patients were requested to rate their pain using a seven-point scale. Comparisons between both groups showed no significant differences on pain referred during the baseline or after the elimination of dietary MSG and aspartame. The discontinuation of dietary MSG and aspartame did not improve the symptoms of fibromyalgia.

  9. Potential land use adjustment for future climate change adaptation in revegetated regions.

    PubMed

    Peng, Shouzhang; Li, Zhi

    2018-05-22

    To adapt to future climate change, appropriate land use patterns are desired. Potential natural vegetation (PNV) emphasizing the dominant role of climate can provide a useful baseline to guide the potential land use adjustment. This work is particularly important for the revegetated regions with intensive human perturbation. However, it has received little attention. This study chose China's Loess Plateau, a typical revegetated region, as an example study area to generate the PNV patterns with high spatial resolution over 2071-2100 with a process-based dynamic vegetation model (LPJ-GUESS), and further investigated the potential land use adjustment through comparing the simulated and observed land use patterns. Compared with 1981-2010, the projected PNV over 2071-2100 would have less forest and more steppe because of drier climate. Subsequently, 25.3-55.0% of the observed forests and 79.3-91.9% of the observed grasslands in 2010 can be kept over 2071-2100, and the rest of the existing forested area and grassland were expected to be more suitable for steppes and forests, respectively. To meet the request of China's Grain for Green Project, 60.9-84.8% of the existing steep farmland could be converted to grassland and the other for forest. Our results highlight the importance in adjusting the existing vegetation pattern to adapt to climate change. The research approach is extendable and provides a framework to evaluate the sustainability of the existing land use pattern under future climate. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Increase in relative skeletal muscle mass over time and its inverse association with metabolic syndrome development: a 7-year retrospective cohort study.

    PubMed

    Kim, Gyuri; Lee, Seung-Eun; Jun, Ji Eun; Lee, You-Bin; Ahn, Jiyeon; Bae, Ji Cheol; Jin, Sang-Man; Hur, Kyu Yeon; Jee, Jae Hwan; Lee, Moon-Kyu; Kim, Jae Hyeon

    2018-02-05

    Skeletal muscle mass was negatively associated with metabolic syndrome prevalence in previous cross-sectional studies. The aim of this study was to investigate the impact of baseline skeletal muscle mass and changes in skeletal muscle mass over time on the development of metabolic syndrome in a large population-based 7-year cohort study. A total of 14,830 and 11,639 individuals who underwent health examinations at the Health Promotion Center at Samsung Medical Center, Seoul, Korea were included in the analyses of baseline skeletal muscle mass and those changes from baseline over 1 year, respectively. Skeletal muscle mass was estimated by bioelectrical impedance analysis and was presented as a skeletal muscle mass index (SMI), a body weight-adjusted appendicular skeletal muscle mass value. Using Cox regression models, hazard ratio for developing metabolic syndrome associated with SMI values at baseline or changes of SMI over a year was analyzed. During 7 years of follow-up, 20.1% of subjects developed metabolic syndrome. Compared to the lowest sex-specific SMI tertile at baseline, the highest sex-specific SMI tertile showed a significant inverse association with metabolic syndrome risk (adjusted hazard ratio [AHR] = 0.61, 95% confidence interval [CI] 0.54-0.68). Furthermore, compared with SMI changes < 0% over a year, multivariate-AHRs for metabolic syndrome development were 0.87 (95% CI 0.78-0.97) for 0-1% changes and 0.67 (0.56-0.79) for > 1% changes in SMI over 1 year after additionally adjusting for baseline SMI and glycometabolic parameters. An increase in relative skeletal muscle mass over time has a potential preventive effect on developing metabolic syndrome, independently of baseline skeletal muscle mass and glycometabolic parameters.

  11. Choice of baseline climate data impacts projected species' responses to climate change.

    PubMed

    Baker, David J; Hartley, Andrew J; Butchart, Stuart H M; Willis, Stephen G

    2016-07-01

    Climate data created from historic climate observations are integral to most assessments of potential climate change impacts, and frequently comprise the baseline period used to infer species-climate relationships. They are often also central to downscaling coarse resolution climate simulations from General Circulation Models (GCMs) to project future climate scenarios at ecologically relevant spatial scales. Uncertainty in these baseline data can be large, particularly where weather observations are sparse and climate dynamics are complex (e.g. over mountainous or coastal regions). Yet, importantly, this uncertainty is almost universally overlooked when assessing potential responses of species to climate change. Here, we assessed the importance of historic baseline climate uncertainty for projections of species' responses to future climate change. We built species distribution models (SDMs) for 895 African bird species of conservation concern, using six different climate baselines. We projected these models to two future periods (2040-2069, 2070-2099), using downscaled climate projections, and calculated species turnover and changes in species-specific climate suitability. We found that the choice of baseline climate data constituted an important source of uncertainty in projections of both species turnover and species-specific climate suitability, often comparable with, or more important than, uncertainty arising from the choice of GCM. Importantly, the relative contribution of these factors to projection uncertainty varied spatially. Moreover, when projecting SDMs to sites of biodiversity importance (Important Bird and Biodiversity Areas), these uncertainties altered site-level impacts, which could affect conservation prioritization. Our results highlight that projections of species' responses to climate change are sensitive to uncertainty in the baseline climatology. We recommend that this should be considered routinely in such analyses. © 2016 John Wiley & Sons Ltd.

  12. Longitudinal evaluation of a World Wide Web-based antimicrobial stewardship program: assessing factors associated with approval patterns and trends over time.

    PubMed

    Venugopal, Vidya; Lehmann, Christoph U; Diener-West, Marie; Agwu, Allison L

    2014-02-01

    The Johns Hopkins Children's Medical and Surgery Center developed a Web-based Antimicrobial Stewardship Program (ASP) in 2005. The present study aimed to assess longitudinal antimicrobial request and approval patterns for this ASP. We analyzed a total of 16,229 antimicrobial requests for 3,542 patients between June 1, 2005, and June 30, 2009. Antimicrobial approval was the outcome of interest. We assessed gaming by studying trends in automatically approved requests. Nonparametric tests for trend were performed to detect changes in approval patterns. Multiple logistic regression was used to identify factors associated with approval. The vast majority (91.3%) of antimicrobial requests were approved, with an increase of 6.1% over time (P < .01). Renewal requests were more likely than primary requests (adjusted odds ratio [aOR], 1.72; 95% confidence interval [CI], 1.45-2.04) to be approved. Antiviral requests had higher odds of approval than antibiotic requests (aOR, 1.27; 95% CI, 1.04-1.56). Compared with requests by medical services, requests by surgical services had lower odds of approval (aOR, 0.70; 95% CI, 0.59-0.83), whereas pediatric intensive care requests had higher odds of approval (aOR, 1.18; 95% CI, 1.00-1.40). The number of auto-approved requests remained consistent. The Web-based ASP allows management of a large number of antimicrobial requests, without apparent gaming. Observed differences in approval patterns based on patient, requestor, and antimicrobial factors may inform the development of ASPs and evaluation of provider education and training. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  13. 77 FR 67442 - Proposed Information Collections; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-09

    ... summarized in our request for Office of Management and Budget (OMB) approval of the relevant information... changes to these two forms, see the TTB announcement posted on the beer page of the TTB Web site at http://www.ttb.gov/beer/index.shtml . Type of Review: Revision of a currently approved collection. Affected...

  14. 77 FR 59167 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... requests authorization from the Office of Management and Budget (OMB) to increase the universe for three of... changes in the population dictate a need to increase the universe up to the age of 54. Raising the age of... organizations use the school enrollment data collected. Increasing the universe will provide data on how federal...

  15. 78 FR 31412 - Drawbridge Operation Regulation; Thea Foss Waterway Previously Known as City Waterway, Tacoma, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... openings during designated hours. This rule also removes previously authorized closure periods for the... for requesting emergency bridge openings. DATES: This rule is effective June 24, 2013. ADDRESSES... needed to request emergency openings of the bridge. C. Discussion of Comments, Changes and the Final Rule...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... Review and Comments Request. Form Title: Short Term Multi-Buyer Export Credit Insurance Policy.... The Short Term Multi-Buyer Export Credit Insurance Policy Application will be used by entities.... Change question three (3) to read ``Do you have an SBA or Ex-Im Bank Working Capital Loan or are you...

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    ... Collection, with Change; Comments Requested: COPS Progress Report ACTION: 60-Day Notice. The Department of Justice (DOJ) Office of Community Oriented Policing Services (COPS) will be submitting the following...; comments requested. (2) Title of the Form/Collection: COPS Progress Report. (3) Agency form number, if any...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... NUCLEAR REGULATORY COMMISSION Request To Amend a License To Import Radioactive Waste Pursuant to... (Class A total of 5,500 ``Foreign Suppliers.'' No IW022/04 radioactive tons of low- other changes to the existing 11005700 waste). level waste). license which authorizes the import of low-level waste for...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... NUCLEAR REGULATORY COMMISSION Request To Amend a License To Export Radioactive Waste Pursuant to...; XW012/03; 11005699. A radioactive total of 5,500 Energy of Canada waste). tons of low- Limited facilities as level waste). ``Ultimate Foreign Consignee(s).'' No other changes to the existing license which...

  1. 75 FR 71568 - Establishment of Negotiated Rulemaking Committee for Changes to Livestock Mandatory Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... solicits comments on this initiative and requests interested parties to nominate representatives for... Committee and, in Section D, Request for Nominations, AMS provides a process for the public to nominate... logistical support to the Committee. In addition, once the Committee is established, it may seek advisors or...

  2. 75 FR 16750 - Request for Comments on Proposed Change To Missing Parts Practice

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... efforts on commercialization during this period. The proposal would benefit the USPTO and the public by... response to a number of requests to reduce the costs due one year after filing a provisional application... that 12-month period. The proposal would benefit applicants by permitting additional time to determine...

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    .... Physical Activity, which includes measures related to change in knowledge, attitudes, behavior, and levels... hours BMI 50 30 1,500 .10 150 Nutrition 50 30 1,500 .20 300 Physical Activity 50 30 1,500 .20 300... Information Collection Activities: Proposed Collection: Comment Request In compliance with the requirement for...

  4. 77 FR 21556 - Don Pedro Hydroelectric Project: Turlock Irrigation District; Modesto Irrigation District...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... studies. All local, state, and federal agencies, Indian tribes, and other interested parties are invited... written submissions as necessary to understand the matters in dispute. The Panel will limit all input that... Rate of Change; Request 7-- Evaluation of the Upper Tuolumne Habitats for Anadromous Fish; Request 8...

  5. 31 CFR 344.3 - What provisions apply to the SLGSafe Service?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... documents, which may be downloaded from BPD's Web site and which may change from time to time, apply to... and other transaction requests exclusively through SLGSafe, except to the extent you establish to the satisfaction of BPD that good cause exists for you to submit such subscriptions and requests by other means...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...-0027] Agency Information Collection Activities: Interagency Record of Request A, G, or NATO Dependent Employment Authorization or Change/ Adjustment To/From A, G, or NATO Status, Form I-566; Revision of a... techniques or other forms of information technology, e.g., permitting electronic submission of responses...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...: Uniform Data Set (UDS)--Reinstatement with Change--OMB No. 0990-0275-Office of Public Health Science (OPHS... approval on a revised collection, Uniform Data Set (OMB No. 0990- 0275), the tool used by the Office Minority Health (OMH) to collect program management and performance data for all OMH-funded projects...

  8. 75 FR 50766 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...). To request a copy of these documents, call the SAMHSA Reports Clearance Officer on (240) 276-1243..., including sustainability of the program or its intended outcomes after Federal funding ends. It also seeks... conclusion of Federal funding, such as capacity improvement, system change, sustainability and influence on...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Submission for OMB Review; 30-day Comment Request: The Clinical Trials Reporting Program (CTRP) Database (NCI) SUMMARY: Under... Program (CTRP) Database, 0925-0600, Expiration Date 3/31/2013--REINSTATEMENT WITH CHANGE, National Cancer...

  10. 76 FR 1434 - Request for Information on 2,3-Pentanedione and Other Alpha-Diketones Used As Diacetyl Substitutes

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  11. Implementing E-Government: A Case Study of Improving the Process for Transferring Conventional Ammunition Among the Military Services

    DTIC Science & Technology

    2003-03-01

    BUSINESS PROCESS REDESIGN.............................................................22 F . SECOND WAVE BPR...Receive/Review/Decide on Lot Data.........................58 f . Step 7 – Create Cross-Leveling Request.................................60 g. Step 8...Compile Cross-Leveling Request...............................60 h. Steps 9 and 10 – (No Change) ................................................60 F

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    2010-06-16

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  16. Politeness Strategies Used in Requests--A Cybernetic Model.

    ERIC Educational Resources Information Center

    Kitao, Kenji

    This paper discusses a cybernetic model of politeness strategies used in the process of making a request. The concept of systems, cybernetic models, and politeness strategies are reviewed, and the way they work together in the proposed model is examined. Politeness strategies are communication strategies used to change behavior enough to achieve…

  17. 78 FR 26035 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... technology to minimize the information collection burden. 1. Type of Information Collection Request: Revision..., such as Part B. The instructions have also been changed to guide plans on when to use this optional... with 45 CFR part 46 or equivalent federal regulations and applicable state or local law or regulations...

  18. 77 FR 65662 - Request for Extension and Revision of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... Stockyards Administration's intention to request that the Office of Management and Budget approve a 3-year... online instructions for submitting comments. Mail, hand deliver, or courier to Dexter Thomas, GIPSA, USDA... subsequent filings of new contracts or changes, as packers initially need to review all their contracts to...

  19. 76 FR 52026 - Agency Forms Submitted for OMB Review, Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    ... AA-104, Application for Canadian Hospital Benefits Under Medicare--Part A, is provided by the RRB to...) submitted: AA-104 Type of request: Revision of a currently approved collection Affected public: Individuals... proposes non-burden impacting formatting and editorial changes to Form AA-104. The burden estimate for the...

  20. Integrating multi-view transmission system into MPEG-21 stereoscopic and multi-view DIA (digital item adaptation)

    NASA Astrophysics Data System (ADS)

    Lee, Seungwon; Park, Ilkwon; Kim, Manbae; Byun, Hyeran

    2006-10-01

    As digital broadcasting technologies have been rapidly progressed, users' expectations for realistic and interactive broadcasting services also have been increased. As one of such services, 3D multi-view broadcasting has received much attention recently. In general, all the view sequences acquired at the server are transmitted to the client. Then, the user can select a part of views or all the views according to display capabilities. However, this kind of system requires high processing power of the server as well as the client, thus posing a difficulty in practical applications. To overcome this problem, a relatively simple method is to transmit only two view-sequences requested by the client in order to deliver a stereoscopic video. In this system, effective communication between the server and the client is one of important aspects. In this paper, we propose an efficient multi-view system that transmits two view-sequences and their depth maps according to user's request. The view selection process is integrated into MPEG-21 DIA (Digital Item Adaptation) so that our system is compatible to MPEG-21 multimedia framework. DIA is generally composed of resource adaptation and descriptor adaptation. It is one of merits that SVA (stereoscopic video adaptation) descriptors defined in DIA standard are used to deliver users' preferences and device capabilities. Furthermore, multi-view descriptions related to multi-view camera and system are newly introduced. The syntax of the descriptions and their elements is represented in XML (eXtensible Markup Language) schema. If the client requests an adapted descriptor (e.g., view numbers) to the server, then the server sends its associated view sequences. Finally, we present a method which can reduce user's visual discomfort that might occur while viewing stereoscopic video. This phenomenon happens when view changes as well as when a stereoscopic image produces excessive disparity caused by a large baseline between two cameras. To solve for the former, IVR (intermediate view reconstruction) is employed for smooth transition between two stereoscopic view sequences. As well, a disparity adjustment scheme is used for the latter. Finally, from the implementation of testbed and the experiments, we can show the valuables and possibilities of our system.

  1. Ethnoracial differences in brain structure change and cognitive change.

    PubMed

    Gavett, Brandon E; Fletcher, Evan; Harvey, Danielle; Farias, Sarah Tomaszewski; Olichney, John; Beckett, Laurel; DeCarli, Charles; Mungas, Dan

    2018-04-12

    The purpose of this study was to examine longitudinal associations between structural MRI and cognition in a diverse sample. Older adults (n = 444; Mage = 74.5)-121 African Americans, 212 Whites, and 111 Hispanics-underwent an average of 5.3 annual study visits. Approximately half were cognitively normal at baseline (global Clinical Dementia Rating M = 0.5). Of the patients with dementia, most (79%) were diagnosed with Alzheimer's disease (AD). MRI measures of gray matter volume (baseline and change), and hippocampal and white matter hyperintensity (WMH) volumes (baseline), were used to predict change in global cognition. Multilevel latent variable modeling was used to test the hypothesis that brain effects on cognitive change differed across ethnoracial groups. In a multivariable model, global gray matter change was the strongest predictor of cognitive decline in Whites and African Americans and specific temporal lobe change added incremental explanatory power in Whites. Baseline WMH volume was the strongest predictor of cognitive decline in Hispanics and made an incremental contribution in Whites. We found ethnoracial group differences in associations of brain variables with cognitive decline. The unique patterns in Whites appeared to suggest a greater influence of AD in this group. In contrast, cognitive decline in African Americans and Hispanics was most uniquely attributable to global gray matter change and baseline WMH, respectively. Brain changes underlying cognitive decline in older adults are heterogeneous and depend on fixed and modifiable risk factors that differ based on ethnicity and race. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  2. Changes in corneal astigmatism during 20 years after cataract surgery.

    PubMed

    Hayashi, Ken; Manabe, Shin-Ichi; Hirata, Akira; Yoshimura, Koichi

    2017-05-01

    To examine how corneal astigmatism changes with age over 20 years after cataract surgery and to assess whether the changes differ from those in eyes that did not have surgery. Hayashi Eye Hospital, Fukuoka, Japan. Retrospective case study. Using an autokeratometer, corneal astigmatism was measured preoperatively, at baseline (the day the surgically induced astigmatism stabilized), and 10 years and 20 years after baseline. The change in corneal astigmatism between baseline and 10 years, 10 years and 20 years, and baseline and 20 years was determined using power vector analysis and compared between the time intervals and between groups. The study assessed 74 eyes that had phacoemulsification with a horizontal scleral incision more than 21 years ago (surgery group) and 68 eyes that did not have surgery (no-surgery group). The mean vertical/horizontal change in corneal astigmatism (J0) between baseline and 20 years was -0.64 diopter (D) in the surgery group and -0.49 D in the no-surgery group. The oblique change (J45) was -0.03 D in the surgery group and 0.07 D in the no-surgery group. Using multivariate comparison, the mean J0 and J45 values were not significantly different between baseline and 10 years or between 10 years and 20 years in both groups (P ≥ .2350). The J0 and J45 values were not significantly different between the 2 groups at any time interval (P ≥ .1331). Corneal astigmatism continues to change toward against-the-rule astigmatism over 20 years after cataract surgery. This change was similar in eyes that did not have surgery. Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  3. Code Lavender: Cultivating Intentional Acts of Kindness in Response to Stressful Work Situations.

    PubMed

    Davidson, Judy E; Graham, Patricia; Montross-Thomas, Lori; Norcross, William; Zerbi, Giovanna

    Providing healthcare can be stressful. Gone unchecked, clinicians may experience decreased compassion, and increased burnout or secondary traumatic stress. Code Lavender is designed to increase acts of kindness after stressful workplace events occur. To test the feasibility of providing Code Lavender. After stressful events in the workplace, staff will provide, receive, and recommend Code Lavender to others. The provision of Code Lavender will improve Professional Quality of Life Scale (ProQoL) scores, general job satisfaction, and feeling cared for in the workplace. Pilot program testing and evaluation. Staff and physicians on four hospital units were informed of the Code Lavender kit availability, which includes words of comfort, chocolate, lavender essential oil, and employee health referral information. Feasibility data and ProQoL scores were collected at baseline and three months. At baseline, 48% (n = 164) reported a stressful event at work in the last three months. Post-intervention, 51% reported experiencing a stressful workplace event, with 32% receiving a Code Lavender kit from their co-workers as a result (n = 83). Of those who received the Code Lavender intervention; 100% found it helpful, and 84% would recommend it to others. No significant changes were demonstrated before and after the intervention in ProQoL scores or job satisfaction, however the emotion of feeling cared-for improved. Results warrant continuation and further dissemination of Code Lavender. Investigators have received requests to expand the program implying positive reception of the intervention. Additional interventions are needed to overcome workplace stressors. A more intense peer support program is being tested. Copyright © 2017. Published by Elsevier Inc.

  4. Is it acceptable to use coagulation plasma samples stored at room temperature and 4°C for 24 hours for additional prothrombin time, activated partial thromboplastin time, fibrinogen, antithrombin, and D-dimer testing?

    PubMed

    Rimac, V; Coen Herak, D

    2017-10-01

    Coagulation laboratories are faced on daily basis with requests for additional testing in already analyzed fresh plasma samples. This prompted us to examine whether plasma samples stored at room temperature (RT), and 4°C for 24 hours can be accepted for additional prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen (Fbg), antithrombin (AT), and D-dimer testing. We measured PT, aPTT, Fbg in 50 and AT in 30 plasma samples with normal and pathological values, within 4 hours of blood collection (baseline results) and after 24-hours storage at RT (primary tubes), and 4°C (aliquots). D-dimer stability was investigated in 20 samples stored in primary tubes at 4°C. No statistically significant difference between baseline results and results in samples stored at RT and 4°C was observed for PT (P=.938), aPTT (P=.186), Fbg (P=.962), AT (P=.713), and D-dimers (P=.169). The highest median percentage changes were found for aPTT, being more pronounced for samples stored at 4°C (13.0%) than at RT (8.7%). Plasma samples stored both at RT and 4°C for 24 hours are acceptable for additional PT, Fbg, and AT testing. Plasma samples stored 24 hours in primary tubes at 4°C are suitable for D-dimer testing. © 2017 John Wiley & Sons Ltd.

  5. Bilingual Text4Walking Food Service Employee Intervention Pilot Study

    PubMed Central

    Ingram, Diana; Wilbur, JoEllen; Fogg, Louis; Sandi, Giselle; Moss, Angela; Ocampo, Edith V

    2016-01-01

    Background Half of all adults in the United States do not meet the level of recommended aerobic physical activity. Physical activity interventions are now being conducted in the workplace. Accessible technology, in the form of widespread usage of cell phones and text messaging, is available for promoting physical activity. Objective The purposes of this study, which was conducted in the workplace, were to determine (1) the feasibility of implementing a bilingual 12-week Text4Walking intervention and (2) the effect of the Text4Walking intervention on change in physical activity and health status in a food service employee population. Methods Before conducting the study reported here, the Text4Walking research team developed a database of motivational physical activity text messages in English. Because Hispanic or Latino adults compose one-quarter of all adults employed in the food service industry, the Text4Walking team translated the physical activity text messages into Spanish. This pilot study was guided by the Physical Activity Health Promotion Framework and used a 1-group 12-week pre- and posttest design with food service employees who self-reported as being sedentary. The aim of the study was to increase the number of daily steps over the baseline by 3000 steps. Three physical activity text messages were delivered weekly. In addition, participants received 3 motivational calls during the study. Results SPSS version 19.0 and R 3.0 were used to perform the data analysis. There were 33 employees who participated in the study (57.6% female), with a mean age of 43.7 years (SD 8.4). The study included 11 Hispanic or Latino participants, 8 of whom requested that the study be delivered in Spanish. There was a 100% retention rate in the study. At baseline, the participants walked 102 (SD 138) minutes/day (per self-report). This rate increased significantly (P=.008) to 182 (SD 219) minutes/day over the course of the study. The participants had a baseline mean of 10,416 (SD 5097) steps, which also increased significantly (P=.017) to 12,540 (SD 5149). They significantly improved their performance on their aerobic fitness test (P<.001). The participants had a baseline mean systolic blood pressure of 120 mm Hg and diastolic blood pressure of 76 mm Hg, a mean body mass index of 29.29 kg/m2, and a mean waist circumference of 36.95 inches, without significant changes seen at 12 weeks. Conclusions We were able to conduct a motivational physical activity text messaging intervention within the workplace setting. Both physical activity and aerobic fitness improved. However, at baseline, participants were more active than they perceived themselves to be. Although there is insufficient evidence to draw strong conclusions about the study findings, it would be useful to test this physical activity text messaging intervention in a sedentary sample within a larger workplace intervention study trial conducted over a longer time frame. PMID:27251878

  6. Bilingual Text4Walking Food Service Employee Intervention Pilot Study.

    PubMed

    Buchholz, Susan Weber; Ingram, Diana; Wilbur, JoEllen; Fogg, Louis; Sandi, Giselle; Moss, Angela; Ocampo, Edith V

    2016-06-01

    Half of all adults in the United States do not meet the level of recommended aerobic physical activity. Physical activity interventions are now being conducted in the workplace. Accessible technology, in the form of widespread usage of cell phones and text messaging, is available for promoting physical activity. The purposes of this study, which was conducted in the workplace, were to determine (1) the feasibility of implementing a bilingual 12-week Text4Walking intervention and (2) the effect of the Text4Walking intervention on change in physical activity and health status in a food service employee population. Before conducting the study reported here, the Text4Walking research team developed a database of motivational physical activity text messages in English. Because Hispanic or Latino adults compose one-quarter of all adults employed in the food service industry, the Text4Walking team translated the physical activity text messages into Spanish. This pilot study was guided by the Physical Activity Health Promotion Framework and used a 1-group 12-week pre- and posttest design with food service employees who self-reported as being sedentary. The aim of the study was to increase the number of daily steps over the baseline by 3000 steps. Three physical activity text messages were delivered weekly. In addition, participants received 3 motivational calls during the study. SPSS version 19.0 and R 3.0 were used to perform the data analysis. There were 33 employees who participated in the study (57.6% female), with a mean age of 43.7 years (SD 8.4). The study included 11 Hispanic or Latino participants, 8 of whom requested that the study be delivered in Spanish. There was a 100% retention rate in the study. At baseline, the participants walked 102 (SD 138) minutes/day (per self-report). This rate increased significantly (P=.008) to 182 (SD 219) minutes/day over the course of the study. The participants had a baseline mean of 10,416 (SD 5097) steps, which also increased significantly (P=.017) to 12,540 (SD 5149). They significantly improved their performance on their aerobic fitness test (P<.001). The participants had a baseline mean systolic blood pressure of 120 mm Hg and diastolic blood pressure of 76 mm Hg, a mean body mass index of 29.29 kg/m2, and a mean waist circumference of 36.95 inches, without significant changes seen at 12 weeks. We were able to conduct a motivational physical activity text messaging intervention within the workplace setting. Both physical activity and aerobic fitness improved. However, at baseline, participants were more active than they perceived themselves to be. Although there is insufficient evidence to draw strong conclusions about the study findings, it would be useful to test this physical activity text messaging intervention in a sedentary sample within a larger workplace intervention study trial conducted over a longer time frame.

  7. 46 CFR 15.505 - Changes in the certificate of inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.505 Changes in the certificate of inspection. All requests for changes in manning as indicated on the certificate of inspection must be made to...

  8. 46 CFR 15.505 - Changes in the certificate of inspection.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.505 Changes in the certificate of inspection. All requests for changes in manning as indicated on the certificate of inspection must be made to...

  9. 46 CFR 15.505 - Changes in the certificate of inspection.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.505 Changes in the certificate of inspection. All requests for changes in manning as indicated on the certificate of inspection must be made to...

  10. 46 CFR 15.505 - Changes in the certificate of inspection.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.505 Changes in the certificate of inspection. All requests for changes in manning as indicated on the certificate of inspection must be made to...

  11. The influence of gene expression profiling on decisional conflict in decision making for early-stage breast cancer chemotherapy.

    PubMed

    MacDonald, Karen V; Bombard, Yvonne; Deal, Ken; Trudeau, Maureen; Leighl, Natasha; Marshall, Deborah A

    2016-07-01

    Women with early-stage breast cancer, of whom only 15% will experience a recurrence, are often conflicted or uncertain about taking chemotherapy. Gene expression profiling (GEP) of tumours informs risk prediction, potentially affecting treatment decisions. We examined whether receiving a GEP test score reduces decisional conflict in chemotherapy treatment decision making. A general population sample of 200 women completed the decisional conflict scale (DCS) at baseline (no GEP test score scenario) and after (scenario with GEP test score added) completing a discrete choice experiment survey for early-stage breast cancer chemotherapy. We scaled the 16-item DCS total scores and subscores from 0 to 100 and calculated means, standard deviations and change in scores, with significance (p < 0.05) based on matched pairs t-tests. We identified five respondent subgroups based on preferred treatment option; almost 40% did not change their chemotherapy decision after receiving GEP testing information. Total score and all subscores (uncertainty, informed, values clarity, support, and effective decision) decreased significantly in the respondent subgroup who were unsure about taking chemotherapy initially but changed to no chemotherapy (n =33). In the subgroup of respondents (n = 25) who chose chemotherapy initially but changed to unsure, effective decision subscore increased significantly. In the overall sample, changes in total and all subscores were non-significant. GEP testing adds value for women initially unsure about chemotherapy treatment with a decrease in decisional conflict. However, for women who are confident about their treatment decisions, GEP testing may not add value. Decisions to request GEP testing should be personalised based on patient preferences. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. The Radiative Forcing Model Intercomparison Project (RFMIP): Experimental protocol for CMIP6

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pincus, Robert; Forster, Piers M.; Stevens, Bjorn

    The phrasing of the first of three questions motivating CMIP6 – “How does the Earth system respond to forcing?” – suggests that forcing is always well-known, yet the radiative forcing to which this question refers has historically been uncertain in coordinated experiments even as understanding of how best to infer radiative forcing has evolved. The Radiative Forcing Model Intercomparison Project (RFMIP) endorsed by CMIP6 seeks to provide a foundation for answering the question through three related activities: (i) accurate characterization of the effective radiative forcing relative to a near-preindustrial baseline and careful diagnosis of the components of this forcing; (ii) assessment ofmore » the absolute accuracy of clear-sky radiative transfer parameterizations against reference models on the global scales relevant for climate modeling; and (iii) identification of robust model responses to tightly specified aerosol radiative forcing from 1850 to present. Complete characterization of effective radiative forcing can be accomplished with 180 years (Tier 1) of atmosphere-only simulation using a sea-surface temperature and sea ice concentration climatology derived from the host model's preindustrial control simulation. Assessment of parameterization error requires trivial amounts of computation but the development of small amounts of infrastructure: new, spectrally detailed diagnostic output requested as two snapshots at present-day and preindustrial conditions, and results from the model's radiation code applied to specified atmospheric conditions. In conclusion, the search for robust responses to aerosol changes relies on the CMIP6 specification of anthropogenic aerosol properties; models using this specification can contribute to RFMIP with no additional simulation, while those using a full aerosol model are requested to perform at least one and up to four 165-year coupled ocean–atmosphere simulations at Tier 1.« less

  13. The Radiative Forcing Model Intercomparison Project (RFMIP): Experimental protocol for CMIP6

    DOE PAGES

    Pincus, Robert; Forster, Piers M.; Stevens, Bjorn

    2016-09-27

    The phrasing of the first of three questions motivating CMIP6 – “How does the Earth system respond to forcing?” – suggests that forcing is always well-known, yet the radiative forcing to which this question refers has historically been uncertain in coordinated experiments even as understanding of how best to infer radiative forcing has evolved. The Radiative Forcing Model Intercomparison Project (RFMIP) endorsed by CMIP6 seeks to provide a foundation for answering the question through three related activities: (i) accurate characterization of the effective radiative forcing relative to a near-preindustrial baseline and careful diagnosis of the components of this forcing; (ii) assessment ofmore » the absolute accuracy of clear-sky radiative transfer parameterizations against reference models on the global scales relevant for climate modeling; and (iii) identification of robust model responses to tightly specified aerosol radiative forcing from 1850 to present. Complete characterization of effective radiative forcing can be accomplished with 180 years (Tier 1) of atmosphere-only simulation using a sea-surface temperature and sea ice concentration climatology derived from the host model's preindustrial control simulation. Assessment of parameterization error requires trivial amounts of computation but the development of small amounts of infrastructure: new, spectrally detailed diagnostic output requested as two snapshots at present-day and preindustrial conditions, and results from the model's radiation code applied to specified atmospheric conditions. In conclusion, the search for robust responses to aerosol changes relies on the CMIP6 specification of anthropogenic aerosol properties; models using this specification can contribute to RFMIP with no additional simulation, while those using a full aerosol model are requested to perform at least one and up to four 165-year coupled ocean–atmosphere simulations at Tier 1.« less

  14. 
Intrathecal analgesia by bupivacaine is not enhanced by coadministration of morphine in patients with severe cancer-related pain: a randomized double-blind cross-over study.

    PubMed

    Reif, Ingalill; Wincent, Anders; Stiller, Carl-Olav

    2017-06-01

    The objective of this randomized double blind cross-over trial was to determine if patients with severe cancer-related pain and inadequate response to systemic opioids prefer intrathecal (IT) pain relief with a combination of bupivacaine and morphine or bupivacaine only. Adult patients with cancer-related pain (n = 23) scheduled for IT analgesia at the Pain Center at the Karo-linska University Hospital Solna, Stockholm, Sweden, were included. The optimal individual flow rate of IT bupivacaine (2 mg/mL) in addition to bolus doses was titrated and maintained for 4 days. Morphine (1 mg/mL) was added to bupivacaine either on day 2 or 4 according to a randomization protocol. Expression of pain relief preference for morphine instead of control (bupivacaine only) was the primary outcome. Secondary outcomes were difference in pain intensity, pain relief, total use of bupivacaine per 24 hours and number of requested bolus doses. Eight patients dropped out during the 4-day study period for reasons not related to the trial. IT bupivacaine significantly decreased median (interquartile range) pain intensity from 5 (3 - 7) at baseline (before catheter insertion) to 1 (0 - 1) (p = 0.0001; Wilcoxon test). Only 1 patient of 15 with 4-day data expressed any preference for morphine. The addition of IT morphine did not result in any significant change of pain intensity, pain relief score, total use of bupivacaine per 24 hours, or number of requested bolus doses. These results suggest that patients with cancer-related pain treated with high doses of systemic opioids, may start IT treatment with an optimal dose of IT bupivacaine without morphine.
.

  15. 7 CFR 3560.405 - Borrower organizational structure or ownership interest changes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Servicing § 3560.405 Borrower organizational structure or ownership interest changes. (a) General. The requirements of this section apply to changes in a borrower entity's organizational structure or to a change in... organizational change. The request must document that the proposed changes will not adversely affect the program...

  16. Environmental Baseline Survey Report for the Title Transfer of Parcel ED-9 at the East Tennessee Technology Park, Oak Ridge, Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    SAIC

    2010-05-01

    This environmental baseline survey (EBS) report documents the baseline environmental conditions of the U. S. Department of Energy's (DOE's) Parcel ED-9 at the East Tennessee Technology Park (ETTP). Parcel ED-9 consists of about 13 acres that DOE proposes to transfer to Heritage Center, LLC (hereafter referred to as 'Heritage Center'), a subsidiary of the Community Reuse Organization of East Tennessee (CROET). The 13 acres include two tracts of land, referred to as ED-9A (7.06 acres) and ED-9B (5.02 acres), and a third tract consisting of about 900 linear feet of paved road and adjacent right-of-way, referred to as ED-9C (0.98more » acres). Transfer of the title to ED-9 will be by deed under a Covenant Deferral Request (CDR) pursuant to Section 120(h)(3)(C) of the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This report provides a summary of information to support the transfer of this government-owned property at ETTP to a non-federal entity.« less

  17. Weight-Control Methods, 3-Year Weight Change, and Eating Behaviors: A Prospective Nationwide Study of Middle-Aged New Zealand Women.

    PubMed

    Leong, Sook Ling; Gray, Andrew; Haszard, Jillian; Horwath, Caroline

    2016-08-01

    The effectiveness of women's weight-control methods and the influences of dieting on eating behaviors remain unclear. Our aim was to determine the association of various weight-control methods at baseline with weight change to 3 years, and examine the association between baseline weight-control status (trying to lose weight, trying to prevent weight gain or no weight-control attempts) and changes in intuitive eating and binge eating at 3 years. A nationally representative sample of 1,601 New Zealand women (40 to 50 years) was recruited and completed a self-administered questionnaire at baseline regarding use of variety of weight-control methods. Information on demographic characteristics, weight, height, food habits, binge eating, and intuitive eating were collected at baseline and 3 years. Linear and logistic regression models examined associations between both weight status and weight-control methods at baseline and weight change to 3 years; and baseline weight-control status and change in intuitive eating from baseline to 3 years and binge eating at 3 years. χ(2) tests were used to cross-sectionally compare food habits across the weight status categories at both baseline and 3 years. Trying to lose weight and the use of weight-control methods at baseline were not associated with change in body weight to 3 years. There were a few differences in the frequency of consumption of high-energy-density foods between those trying to lose or maintain weight and those not attempting weight control. Trying to lose weight at baseline was associated with a 2.0-unit (95% CI 0.7 to 3.4, P=0.003) reduction in intuitive eating scores by 3 years (potential range=21 to 105), and 224% (odds ratio=3.24; 95% CI 1.69 to 6.20; P<0.001) higher odds of binge eating at 3 years. The apparent ineffectiveness of dieting and weight-control behaviors may reflect misconceptions about what constitutes healthy eating or energy-dense foods. Dieting may reduce women's ability to recognize hunger and satiety cues and place women at increased risk of binge eating. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  18. Determinants of change in polypharmacy status in Switzerland: the population-based CoLaus study.

    PubMed

    Abolhassani, Nazanin; Castioni, Julien; Marques-Vidal, Pedro; Vollenweider, Peter; Waeber, Gérard

    2017-09-01

    This study aimed to assess the prevalence, the change, and the determinants of change in polypharmacy in a population-based sample. Baseline (2003-2006) and follow-up (2009-2012) data are from 4679 participants aged between 35 and 75 years (53.5% women, mean age 52.6 ± 10.6 years) from the population of Lausanne, Switzerland. Polypharmacy was defined by the regular use of ≥5 drugs. Four categories of change were defined: never (no polypharmacy at baseline and follow-up), initiating (no polypharmacy at baseline but at follow-up), maintaining, or quitting. Polypharmacy increased from 7.7% at baseline to 15.3% at follow-up. Cardiovascular drugs were the most prescribed medicines at baseline and follow-up. Gender, age, obesity, smoking, previously diagnosed hypertension, or diabetes or dyslipidemia were significantly and independently associated with initiating and maintaining polypharmacy. In a population-based sample, prevalence of polypharmacy doubled over a 5.6-year period. The main determinants of initiating polypharmacy were age, overweight and obesity, smoking status, and previously diagnosed cardiovascular risk factors.

  19. Visual Acuity Change over 12 Months in the Prospective Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Study: ProgStar Report Number 6.

    PubMed

    Kong, Xiangrong; Strauss, Rupert W; Cideciyan, Artur V; Michaelides, Michel; Sahel, José-Alain; Munoz, Beatriz; Ahmed, Mohamed; Ervin, Ann M; West, Sheila K; Cheetham, Janet K; Scholl, Hendrik P N

    2017-11-01

    To estimate the yearly rate of change of best-corrected visual acuity (BCVA) and the risk of loss 1 line or more over 1 year and to identify risk factors for BCVA loss in patients with Stargardt disease (STGD1). Multicenter, prospective cohort study. Two hundred fifty-nine patients (489 eyes) with molecularly confirmed STGD1 enrolled at 9 centers in the United States and Europe. Participants were followed up every 6 months, and data at the baseline and 6- and 12-month visits were analyzed. Best-corrected visual acuity was measured using the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol. Standardized reporting forms were used to collect participants' characteristics and clinical observations. Linear mixed effects models were used to estimate the rate of BCVA loss. Linear models with generalized estimating equations were used to identify risk factors for BCVA loss of 1 line or more over 1 year. Change in BCVA over 1 year. Cross-sectional analysis at baseline showed that earlier symptom onset and longer duration since onset was associated with worse BCVA. Longitudinal analysis showed no overall significant change of BCVA within 12 months, but the rate of BCVA change was significantly different by baseline BCVA (P < 0.001). The BCVA of eyes with baseline BCVA of 20/25 or better declined at a rate of 2.8 ETDRS letters per year (P = 0.10), eyes with baseline BCVA between 20/25 and 20/70 declined at a rate of 2.3 ETDRS letters per year (P = 0.002), eyes with baseline BCVA between 20/70 and 20/200 declined at a rate of 0.8 ETDRS letters per year (P = 0.08), and eyes with baseline BCVA worse than 20/200 showed a significant improvement of 2.3 ETDRS letters per year (P < 0.001). Overall, 12.9% of eyes lost 1 line or more, and the risk of such BCVA loss was different by baseline BCVA level (P = 0.016). Smoking and vitamin A use was not associated significantly with baseline BCVA, nor with rate of BCVA loss over 1 year. Change in BCVA in STGD1 patients over a 12-month period was small, but varied depending on baseline BCVA. Given the slow change during 1 year, BCVA is unlikely to be a sensitive outcome measure for STGD1 treatment trials with 1 year's duration. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  20. Understanding the role of emotion-oriented coping in women's motivation for change.

    PubMed

    Wu, Qiong; Slesnick, Natasha; Zhang, Jing

    2018-03-01

    This study tested a sequential mediation model that emotion-oriented coping and motivation for change mediate the relations between anxiety and depressive symptoms and the change in substance use. Data included 183 substance using women, randomly assigned to family therapy (N=123) or individual therapy (N=60). They reported their baseline anxiety and depressive symptoms, emotion-oriented coping, as well as motivation for change throughout treatment, and substance use over a time period of 1.5years. Latent growth curve modeling showed that increased baseline motivation was associated with a faster decline in alcohol and drug use. Moreover, higher baseline anxiety and depressive symptoms were associated with a faster decrease in drug use through higher emotion-oriented coping and higher baseline motivation. This study underscores the importance of emotion-oriented coping in increasing clients' motivation and reducing their drug use. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. 75 FR 10529 - Mail Classification Change

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... POSTAL REGULATORY COMMISSION [Docket Nos. MC2010-19; Order No. 415] Mail Classification Change...-filed Postal Service request to make a minor modification to the Mail Classification Schedule. The.... concerning a change in classification which reflects a change in terminology from Bulk Mailing Center (BMC...

  2. 46 CFR 15.505 - Changes in the certificate of inspection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MANNING REQUIREMENTS Manning Requirements; Inspected Vessels § 15.505 Changes in the certificate of inspection. All requests for changes to the manning required on the COI must be made to the OCMI who last...

  3. 26 CFR 1.167(e)-1 - Change in method.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... percent of the straight line rate, or any change in the interest factor used in connection with a compound interest or sinking fund method, will constitute a change in method of depreciation. Any request for a...

  4. 75 FR 3387 - Outer Continental Shelf Air Regulations Consistency Update for Alaska

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... Explanation of Proposed Changes'' identifies changes and rational for each change made in the rules. These... change made to part 55, with a rational for each change. Response: The changes to the regulations are explained above. This comment requesting that the rational for each change be explained is beyond the scope...

  5. 77 FR 58097 - Extension of Comment Period for Request for Comments Regarding Amending the First Filing Deadline...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ...] Extension of Comment Period for Request for Comments Regarding Amending the First Filing Deadline for... comment regarding a potential legislative change to amend the first filing deadline for Affidavits or... why such an amendment is or is not favored. DATES: Written comments must be received on or before...

  6. 78 FR 69083 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; 8-Hour...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... received will be included in the public docket without change including any personal information provided... Code C539- 01, Environmental Protection Agency, T.W. Alexander Drive, Research Triangle Park, NC 27711... promulgated in two Phases: Phase 1 published on April 30, 2004, (69 FR 23951) and Phase 2 published on...

  7. 77 FR 74002 - Proposed Information Collection Request; Comment Request; Technical Assistance Needs Assessments...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... with the Paperwork Reduction Act (44 U.S.C. 3501 et seq.). Before doing so, EPA is soliciting public... received will be included in the public docket without change including any personal information provided... the EPA will be collecting are available in the public docket for this ICR. The docket can be viewed...

  8. Conversion of the Livermore Education Center to College Status.

    ERIC Educational Resources Information Center

    Freitas, Joseph M.; And Others

    In March 1988, the South County Community College District (SCCCD) requested the approval of the Board of Governors of the California Community Colleges to change the status of the Livermore Education Center from an "educational center" to a "college." An analysis by the Chancellor's Office of the request indicated that the District met Title 5…

  9. 76 FR 67506 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Expanding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... Potential ``Users'' of Its Co-Location Services To Include Any Market Participant That Requests To Receive Co-Location Services Directly From the Exchange and Amending Its Price List To Establish a Fee for... scope of potential ``Users'' of its co-location services to include any market participant that requests...

  10. 76 FR 67522 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... Potential ``Users'' of Its Co-Location Services To Include Any Market Participant That Requests To Receive Co-Location Services Directly From the Exchange and Amending Its Fee Schedule To Establish a Fee for... scope of potential ``Users'' of its co-location services to include any market participant that requests...

  11. 77 FR 63727 - Drawbridge Operation Regulation; Schuylkill River, Philadelphia, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... 51 MGT of freight every year. However, over the past 13 years the bridge logs show that there has..., because there have been no requests for openings for the past 13 years, and there is no anticipated change... no requests for openings in 13 years. DATES: This rule is effective November 16, 2012. [[Page 63728...

  12. 76 FR 18399 - Changes To Implement the Prioritized Examination Track (Track I) of the Enhanced Examination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... questioned whether the processing fee was required only if early publication was requested. Response: Both... fee for requesting early publication. Comment 5: A few comments indicated that the fee for prioritized... applicant being unable to amend the claims to place them in independent form after a final rejection where...

  13. 76 FR 10226 - Airworthiness Directives; The Boeing Company Model 757 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... contents of the proposed rule. Request To Revise the Compliance Time FedEx, US Airways, Delta, European Air Transport Leipzig GmbH (European Air)/DHL Air requested a change in the compliance time. FedEx, Delta, and..., dated July 16, 2007. FedEx and Delta stated that fuel tank access occurs at 72-month intervals. European...

  14. 36 CFR 228.104 - Consideration of requests to modify, waive, or grant exceptions to lease stipulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... An operator submitting a surface use plan of operations may request the authorized Forest officer to authorize the Bureau of Land Management to modify (permanently change), waive (permanently remove), or grant... Forest officer may authorize the Bureau of Land Management to modify, waive, or grant an exception to a...

  15. 75 FR 57955 - Agency Information Collection Request; 30-Day Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... approval on a revised collection, Uniform Data Set (OMB No. 0990- 0275), the tool used by the Office... notice directly to the OS OMB Desk Officer; faxed to OMB at 202-395-5806. Proposed Project: Uniform Data Set (UDS)--Reinstatement with Change--OMB No. 0990-0275-Office of Public Health Science (OPHS...

  16. 76 FR 48058 - Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... embolism, muscle/nerve stimulation, stenosis, and erosion/extrusion may occur as a result of the clinical... advises that to ensure timely filing of any such petition, any request should be submitted to the Division... timely request for a change in the classification of this device is submitted, the Agency will, within 60...

  17. 77 FR 37713 - Comment Request for Information Collection for ETA 9162, Random Audit of EUC 2008 Claimants...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... Collection for ETA 9162, Random Audit of EUC 2008 Claimants, Comment Request for Extension Without Change... assessed. Currently, ETA is soliciting comments concerning the collection of data about Random Audit of... describing random audits of the work search provision of Public Law 112-96 (see Section 2141(b)). Random...

  18. 12 CFR 225.89 - How to request approval to engage in an activity that is complementary to a financial activity?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding Companies § 225.89 How to request... holding company and to the financial system generally; (5) Describe the potential adverse effects... effects. (c) Board action. The Board will inform the financial holding company in writing of the Board's...

  19. 76 FR 6598 - Notice of Intent To Request Revision and Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... Clearance for Survey Research Studies. Revision to burden hours may be needed due to changes in the size of the target population, sampling design, and/or questionnaire length. DATES: Comments on this notice... Survey Research Studies. OMB Control Number: 0535-0248. Type of Request: To revise and extend a currently...

  20. 77 FR 75120 - Notice of Intent To Request Revision and Extension of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... Clearance for Survey Research Studies. Revision to burden hours will be needed due to changes in the size of the target population, sampling design, and/or questionnaire length. DATES: Comments on this notice... Survey Research Studies. OMB Control Number: 0535-0248. Type of Request: To revise and extend a currently...

  1. 78 FR 72079 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NSPS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... Utility Steam Generating Units (40 CFR Part 60, Subpart Da) (Renewal)'' (EPA ICR No. 1053.11, OMB Control..., and any changes, or additions to the Provisions, are specified at 40 CFR part 60, subpart Da. Owners... part 60, subpart Da). Estimated number of respondents: 710 (total). Frequency of response: Initially...

  2. 78 FR 27951 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-13

    ...-0757. Form Number(s): H-100, H-108, H-100(L), H-100L(A). Type of Request: Reinstatement, with change... vacancy rate of housing in the city. The NYCHPD must take this survey every three years. The Census Bureau... rental or real estate agent (vacant units) to gather information on vacancy rates, housing costs, and the...

  3. 77 FR 3289 - Agency Forms Submitted for OMB Review, Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... uses Form AA-6, Employee Application for Medicare; Form AA-7, Spouse/Divorced Spouse Application for Medicare; and Form AA-8, Widow/Widower Application for Medicare; to obtain the information needed to.... Forms submitted: AA-6, AA-7, AA-8, RL-311-F. Type of request: Extension without change of a currently...

  4. Effects of Evolocumab on Vitamin E and Steroid Hormone Levels: Results From the 52-Week, Phase 3, Double-Blind, Randomized, Placebo-Controlled DESCARTES Study.

    PubMed

    Blom, Dirk J; Djedjos, C Stephen; Monsalvo, Maria Laura; Bridges, Ian; Wasserman, Scott M; Scott, Rob; Roth, Eli

    2015-09-25

    Vitamin E transport and steroidogenesis are closely associated with low-density lipoproteins (LDLs) metabolism, and evolocumab can lower LDL cholesterol (LDL-C) to low levels. To determine the effects of evolocumab on vitamin E and steroid hormone levels. After titration of background lipid-lowering therapy per cardiovascular risk, 901 patients with an LDL-C ≥2.0 mmol/L were randomized to 52 weeks of monthly, subcutaneous evolocumab, or placebo. Vitamin E, cortisol, adrenocorticotropic hormone, and gonadal hormones were analyzed at baseline and week 52. In a substudy (n=100), vitamin E levels were also measured in serum, LDL, high-density lipoprotein, and red blood cell membranes at baseline and week 52. Absolute vitamin E decreased in evolocumab-treated patients from baseline to week 52 by 16% but increased by 19% when normalized for cholesterol. In the substudy, vitamin E level changes from baseline to week 52 mirrored the changes in the lipid fraction, and red blood cell membrane vitamin E levels did not change. Cortisol in evolocumab-treated patients increased slightly from baseline to week 52, but adrenocorticotropic hormone and the cortisol:adrenocorticotropic hormone ratio did not change. No patient had a cortisol:adrenocorticotropic hormone ratio <3.0 (nmol/pmol). Among evolocumab-treated patients, gonadal hormones did not change from baseline to week 52. Vitamin E and steroid changes were consistent across subgroups by minimum postbaseline LDL-C <0.4 and <0.6 mmol/L. As expected, vitamin E levels changed similarly to lipids among patients treated for 52 weeks with evolocumab. No adverse effects were observed in steroid or gonadal hormones, even at very low LDL-C levels. URL: http://www.clinicaltrials.gov. Unique identifier: NCT01516879. © 2015 American Heart Association, Inc.

  5. Direct-to-consumer advertising: public perceptions of its effects on health behaviors, health care, and the doctor-patient relationship.

    PubMed

    Murray, Elizabeth; Lo, Bernard; Pollack, Lance; Donelan, Karen; Lee, Ken

    2004-01-01

    To determine public perceptions of the effect of direct-to-consumer advertising (DTCA) of prescription medications on health behaviors, health care utilization, the doctor-patient relationship, and the association between socioeconomic status and these effects. Cross-sectional survey of randomly selected, nationally representative sample of the US public using computer-assisted telephone interviewing. numbers and proportions of respondents in the past 12 months who, as a result of DTCA, requested preventive care or scheduled a physician visit; were diagnosed with condition mentioned in advertisement; disclosed health concerns to a doctor; felt enhanced confidence or sense of control; perceived an effect on the doctor-patient relationship; requested a test, medication change, or specialist referral; or manifested serious dissatisfaction after a visit to a doctor. As a result of DTCA, 14% of respondents disclosed health concerns to a physician, 6% requested preventive care, 5% felt more in control during a physician visit; 5% made requests for a test, medication change, or specialist referral, and 3% received the requested intervention. One percent of patients reported negative outcomes, including worsened treatment, serious dissatisfaction with the visit, or that the physician acted challenged. Effects of DTCA were greater for respondents with low socioeconomic status. DTCA has positive and negative effects on health behaviors, health service utilization, and the doctor-patient relationship that are greatest on people of low socioeconomic status. The benefits of DTCA in terms of encouraging hard-to-reach sections of the population to seek preventive care must be balanced against increased health care costs caused by clinically inappropriate requests generated by DTCA.

  6. Coal Transportation Rate Sensitivity Analysis

    EIA Publications

    2005-01-01

    On December 21, 2004, the Surface Transportation Board (STB) requested that the Energy Information Administration (EIA) analyze the impact of changes in coal transportation rates on projected levels of electric power sector energy use and emissions. Specifically, the STB requested an analysis of changes in national and regional coal consumption and emissions resulting from adjustments in railroad transportation rates for Wyoming's Powder River Basin (PRB) coal using the National Energy Modeling System (NEMS). However, because NEMS operates at a relatively aggregate regional level and does not represent the costs of transporting coal over specific rail lines, this analysis reports on the impacts of interregional changes in transportation rates from those used in the Annual Energy Outlook 2005 (AEO2005) reference case.

  7. Association of baseline knee bone size, cartilage volume, and body mass index with knee cartilage loss over time: a longitudinal study in younger or middle-aged adults.

    PubMed

    Antony, Benny; Ding, Changhai; Stannus, Oliver; Cicuttini, Flavia; Jones, Graeme

    2011-09-01

    To determine the association of knee bone size, cartilage volume, and body mass index (BMI) at baseline with knee cartilage loss over 2 years in younger or middle-aged adults. A total of 324 subjects (mean age 45 yrs, range 26-61) were measured at baseline and about 2 years later. Knee cartilage volume and bone size were determined using T1-weighted fat-saturated magnetic resonance imaging. In multivariable analysis, baseline knee bone size was negatively associated with annual change in knee cartilage volume at medial and lateral tibial sites (ß = -0.62% to -0.47%/cm(2), all p < 0.001). The associations disappeared at medial tibial site after adjustment for baseline cartilage volume and became of borderline statistical significance at lateral tibial site after adjustment for both baseline cartilage volume and osteophytes (ß = -0.29, p = 0.059). Baseline knee cartilage volume was consistently and negatively associated with annual change in knee cartilage volume at all 3 medial tibial, lateral tibial, and patellar sites (ß = -4.41% to -1.37%/ml, all p < 0.001). Baseline BMI was negatively associated with an annual change in knee cartilage volume, but only in subjects within the upper tertile of baseline cartilage volume, even after adjusting for cartilage defects (ß = -0.16% to -0.34%/kg/m(2), all p < 0.05). Our study suggests that both higher baseline tibial bone area and knee cartilage volume (most likely due to cartilage swelling) are associated with greater knee cartilage loss over 2 years. A higher BMI was associated with greater knee cartilage loss only in subjects with higher baseline cartilage volume.

  8. Extending solid state laser performance

    NASA Astrophysics Data System (ADS)

    Miesak, Ed

    2017-02-01

    Coherent Diode-Pumped Solid-State Orlando (CDO), formerly known as Lee Laser, headquartered in Orlando Florida produces CW and pulsed solid state lasers. Primary wavelengths include 1064 nm, 532 nm, and 355 nm. Other wavelengths produced include 1320 nm, 15xx nm, and 16xx nm. Pulse widths are in the range of singles to hundreds of nanoseconds. Average powers are in the range of a few watts to 1000 watts. Pulse repetition rates are typically in the range of 100 Hz to 100 KHz. Laser performance parameters are often modified according to customer requests. Laser parameters that can be adjusted include average power, pulse repetition rate, pulse length, beam quality, and wavelength. Laser parameters are typically cross-coupled such that adjusting one may change some or all of the others. Customers often request one or more parameters be changed without changing any of the remaining parameters. CDO has learned how to accomplish this successfully with rapid turn-around times and minimal cost impact. The experience gained by accommodating customer requests has produced a textbook of cause and effect combinations of laser components to accomplish almost any parameter change request. Understanding the relationships between component combinations provides valuable insight into lasing effects allowing designers to extend laser performance beyond what is currently available. This has led to several break through products, i.e. >150W average power 355 nm, >60W average power 6 ps 1064 nm, pulse lengths longer than 400 ns at 532 nm with average power >100W, >400W 532 nm with pulse lengths in the 100 ns range.

  9. Predictors of long-term change of a physical activity promotion programme in primary care.

    PubMed

    Sanchez, Alvaro; Grandes, Gonzalo; Ortega Sánchez-Pinilla, Ricardo; Torcal, Jesus; Montoya, Imanol

    2014-02-04

    Further research is needed to improve the evidence regarding determinants of physical activity (PA) as a crucial step to plan higher effective intervention strategies. The goal of the present study is to identify socio-demographic and clinical characteristics of primary care (PHC) insufficiently active patients that are associated with longitudinal changes in the level of physical activity. Longitudinal analysis of baseline socio-demographic and clinical predictors of physical activity change in insufficiently active PHC patients who participated in a PA-promoting multi-centre randomized clinical trial conducted from October 2003 through March 2006. The primary outcome measure was the self-reported physical activity assessed with the 7-day Physical Activity Recall (PAR), at baseline, 6, 12 and 24 months. Baseline covariates included sex, age, social class, anthropometric measures and other cardiovascular risk factors or associated diseases (Diabetes, HTA, tobacco use, etc.), and stage of readiness to change PA. Generalized linear mixed models were used to estimate longitudinal association of studied variables on PA change over the three follow-up measurements. A total of 3691 patients (85% of the 4317 recruited in the trial) with at least one follow-up measurement were included in the longitudinal analysis. At baseline, analysed patients (mean age: 50.6 years; 64.6% women) devoted 34.7 minutes and 2.36 metabolic equivalent hours per week (MET.h/week) to moderate and vigorous physical activity. Older age, male gender, higher social class, lower BMI, diagnosis of diabetes or hypertension, and measurement season were significant predictors of PA longitudinal change. The effect of baseline readiness to change on PA dose was modified by time, showing a positive gradient in favour of those with more readiness to change that increases significantly at 12 and 24 months (p-value interaction < .0001). Identified baseline characteristics such as readiness to change and risk factors can guide physicians to prioritize time and intervention efforts for maximizing their impact on insufficiently active PHC patients.

  10. 40 CFR 35.114 - Amendments and other changes.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Amendments and other changes. The provisions of 40 CFR 31.30 do not apply to environmental program grants.... Recipients must request, in writing, grant amendments for changes requiring increases in environmental... specific recipients and costs contained in OMB cost principles. (e) Changes in consolidated grants...

  11. 40 CFR 35.114 - Amendments and other changes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Amendments and other changes. The provisions of 40 CFR 31.30 do not apply to environmental program grants.... Recipients must request, in writing, grant amendments for changes requiring increases in environmental... specific recipients and costs contained in OMB cost principles. (e) Changes in consolidated grants...

  12. Autonomous Preference-Aware Information Services Integration for High Response in Integrated Faded Information Field Systems

    NASA Astrophysics Data System (ADS)

    Lu, Xiaodong; Mori, Kinji

    The market and users' requirements have been rapidly changing and diversified. Under these heterogeneous and dynamic situations, not only the system structure itself, but also the accessible information services would be changed constantly. To cope with the continuously changing conditions of service provision and utilization, Faded Information Field (FIF) has been proposed, which is a agent-based distributed information service system architecture. In the case of a mono-service request, the system is designed to improve users' access time and preserve load balancing through the information structure. However, with interdependent requests of multi-service increasing, adaptability and timeliness have to be assured by the system. In this paper, the relationship that exists among the correlated services and the users' preferences for separate and integrated services is clarified. Based on these factors, the autonomous preference-aware information services integration technology to provide one-stop service for users multi-service requests is proposed. As compared to the conventional system, we show that proposed technology is able to reduce the total access time.

  13. Association of Fetal Heart Rate Baseline Change and Neonatal Outcomes.

    PubMed

    Yang, Michael; Stout, Molly J; López, Julia D; Colvin, Ryan; Macones, George A; Cahill, Alison G

    2017-07-01

    Objective  The objective of this study was to describe the incidence of baseline change within normal range during labor and its prediction of neonatal outcomes. Materials and Methods  This was a prospective cohort of singleton, nonanomalous, term neonates with continuous electronic fetal monitoring and normal baseline fetal heart rate throughout the last 2 hours of labor. We determined baseline in 10-minute segments using Eunice Kennedy Shriver National Institute of Child Health and Human Development criteria. We evaluated baseline changes of ≥ 20 and ≥ 30 bpm for association with acidemia (umbilical cord arterial pH ≤ 7.10) and neonatal intensive care unit (NICU) admission. Finally, we performed a sensitivity analysis of normal neonates, excluding those with acidemia, NICU admission, or 5-minute Apgar < 4. Results  Among all neonates ( n  = 3,021), 1,267 (41.9%) had change ≥ 20 bpm; 272 (9.0%) had ≥ 30 bpm. Among normal neonates ( n  = 2,939), 1,221 (41.5%) had change ≥20 bpm. Acidemia was not associated with baseline change of any direction or magnitude. NICU admission was associated with decrease ≥ 20 bpm (adjusted odds ratio [aOR]: 2.93; 95% confidence interval [CI]: 1.19 - 7.21) or any direction ≥ 20 bpm (aOR: 4.06; 95% CI: 1.46-11.29). For decrease ≥ 20 bpm, sensitivity and specificity were 40.0 and 81.7%; for any direction ≥ 20 bpm, 75.0 and 58.3%. Conclusion  Changes of normal baseline are common in term labor and poorly predict morbidity, regardless of direction or magnitude. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  14. The Whole-Brain “Global” Signal from Resting State fMRI as a Potential Biomarker of Quantitative State Changes in Glucose Metabolism

    PubMed Central

    Thompson, Garth J.; Grimmer, Timo; Drzezga, Alexander; Herman, Peter

    2016-01-01

    Abstract The evolution of functional magnetic resonance imaging to resting state (R-fMRI) allows measurement of changes in brain networks attributed to state changes, such as in neuropsychiatric diseases versus healthy controls. Since these networks are observed by comparing normalized R-fMRI signals, it is difficult to determine the metabolic basis of such group differences. To investigate the metabolic basis of R-fMRI network differences within a normal range, eyes open versus eyes closed in healthy human subjects was used. R-fMRI was recorded simultaneously with fluoro-deoxyglucose positron emission tomography (FDG-PET). Higher baseline FDG was observed in the eyes open state. Variance-based metrics calculated from R-fMRI did not match the baseline shift in FDG. Functional connectivity density (FCD)-based metrics showed a shift similar to the baseline shift of FDG, however, this was lost if R-fMRI “nuisance signals” were regressed before FCD calculation. Average correlation with the mean R-fMRI signal across the whole brain, generally regarded as a “nuisance signal,” also showed a shift similar to the baseline of FDG. Thus, despite lacking a baseline itself, changes in whole-brain correlation may reflect changes in baseline brain metabolism. Conversely, variance-based metrics may remain similar between states due to inherent region-to-region differences overwhelming the differences between normal physiological states. As most previous studies have excluded the spatial means of R-fMRI metrics from their analysis, this work presents the first evidence of a potential R-fMRI biomarker for baseline shifts in quantifiable metabolism between brain states. PMID:27029438

  15. The Whole-Brain "Global" Signal from Resting State fMRI as a Potential Biomarker of Quantitative State Changes in Glucose Metabolism.

    PubMed

    Thompson, Garth J; Riedl, Valentin; Grimmer, Timo; Drzezga, Alexander; Herman, Peter; Hyder, Fahmeed

    2016-07-01

    The evolution of functional magnetic resonance imaging to resting state (R-fMRI) allows measurement of changes in brain networks attributed to state changes, such as in neuropsychiatric diseases versus healthy controls. Since these networks are observed by comparing normalized R-fMRI signals, it is difficult to determine the metabolic basis of such group differences. To investigate the metabolic basis of R-fMRI network differences within a normal range, eyes open versus eyes closed in healthy human subjects was used. R-fMRI was recorded simultaneously with fluoro-deoxyglucose positron emission tomography (FDG-PET). Higher baseline FDG was observed in the eyes open state. Variance-based metrics calculated from R-fMRI did not match the baseline shift in FDG. Functional connectivity density (FCD)-based metrics showed a shift similar to the baseline shift of FDG, however, this was lost if R-fMRI "nuisance signals" were regressed before FCD calculation. Average correlation with the mean R-fMRI signal across the whole brain, generally regarded as a "nuisance signal," also showed a shift similar to the baseline of FDG. Thus, despite lacking a baseline itself, changes in whole-brain correlation may reflect changes in baseline brain metabolism. Conversely, variance-based metrics may remain similar between states due to inherent region-to-region differences overwhelming the differences between normal physiological states. As most previous studies have excluded the spatial means of R-fMRI metrics from their analysis, this work presents the first evidence of a potential R-fMRI biomarker for baseline shifts in quantifiable metabolism between brain states.

  16. Evaluation of a curriculum for intimate partner violence screening in a pediatric emergency department.

    PubMed

    Knapp, Jane F; Dowd, M Denise; Kennedy, Christopher S; Stallbaumer-Rouyer, Jennifer; Henderson, Deborah P

    2006-01-01

    We sought to describe the assessment of course participant changes in attitudes, self-efficacy, and behaviors after completion of the Its Time to Ask training curriculum for screening for intimate partner violence (IPV) in a pediatric emergency department (PED). A 22-item Likert scale questionnaire was administered at baseline (before training), after training, and at 6-month follow-up to PED employee participants in a 2-hour IPV education program. Mean participant responses were compared between baseline/posttraining and baseline/6-month follow-up. Participants also completed a course-satisfaction survey. A total of 79 PED staff completed the baseline questionnaire before the training. Eighty-seven participants completed the posttraining questionnaire, and 48 completed the 6-month follow-up questionnaire. Participants had consistent, positive changes in attitudes after training that persisted at the 6-month follow-up for 5 items on the questionnaire. Attitudes that did not change showed baseline means already in disagreement with questionnaire statements. Participants reported significant, positive changes for all 7 self-efficacy statements at 1 or both of the posttraining evaluations. The only changes in behavior were observed at 6 months. The majority of participants were satisfied with the training and would recommend it to colleagues. Significant, self-reported changes in attitudes, self-efficacy, and behaviors/clinical practice regarding screening for IPV in a PED can be achieved through participation in a brief training curriculum.

  17. Baseline Body Mass Index and the Efficacy of Hypoglycemic Treatment in Type 2 Diabetes: A Meta-Analysis.

    PubMed

    Cai, Xiaoling; Yang, Wenjia; Gao, Xueying; Zhou, Lingli; Han, Xueyao; Ji, Linong

    2016-01-01

    The aim of this study is to compare the effects of hypoglycemic treatments in groups of patients categorized according to the mean baseline body mass indexes (BMIs). Studies were identified by a literature search and all the studies were double blind, placebo-controlled randomized trials in type 2 diabetes patients; study length of ≥12 weeks with the efficacy evaluated by changes in HbA1c from baseline in groups. The electronic search was first conducted in January 2015 and repeated in June 2015. 227 studies were included. Treatment with sulfonylureas was compared with placebo in overweight patients and resulted in a significantly greater change in the HbA1c levels (weighted mean difference (WMD), -1.39%) compared to obese patients (WMD, -0.77%)(p<0.05). Treatment with metformin in overweight patients resulted in a comparable change in the HbA1c levels (WMD, -0.99%) compared to obese patients (WMD, -1.06%)(p>0.05). Treatment with alpha glucosidase inhibitors in normal weight patients was associated with a HbA1c change (WMD, -0.94%) that was comparable that in overweight (WMD, -0.72%) and obese patients (WMD, -0.56%)(p>0.05). Treatment with thiazolidinediones in normal weight patients was associated with a HbA1c change (WMD, -1.04%) that was comparable with that in overweight (WMD, -1.02%) and obese patients (WMD, -0.88%)(p>0.05). Treatment with DPP-4 inhibitors in normal weight patients was associated with a HbA1c change (WMD, -0.93%) that was comparable with that in overweight (WMD, -0.66%) and obese patients (WMD, -0.61%)(p>0.05). In total, of the seven hypoglycemic agents, regression analysis indicated that the mean baseline BMI was not associated with the mean HbA1c changes from baseline. In each kind of hypoglycemic therapy in type 2 diabetes, the baseline BMI was not associated with the efficacy of HbA1c changes from baseline.

  18. Baseline Body Mass Index and the Efficacy of Hypoglycemic Treatment in Type 2 Diabetes: A Meta-Analysis

    PubMed Central

    Cai, Xiaoling; Yang, Wenjia; Gao, Xueying; Zhou, Lingli; Han, Xueyao; Ji, Linong

    2016-01-01

    Aim The aim of this study is to compare the effects of hypoglycemic treatments in groups of patients categorized according to the mean baseline body mass indexes (BMIs). Methods Studies were identified by a literature search and all the studies were double blind, placebo-controlled randomized trials in type 2 diabetes patients; study length of ≥12 weeks with the efficacy evaluated by changes in HbA1c from baseline in groups. The electronic search was first conducted in January 2015 and repeated in June 2015. Results 227 studies were included. Treatment with sulfonylureas was compared with placebo in overweight patients and resulted in a significantly greater change in the HbA1c levels (weighted mean difference (WMD), −1.39%) compared to obese patients (WMD, −0.77%)(p<0.05). Treatment with metformin in overweight patients resulted in a comparable change in the HbA1c levels (WMD, −0.99%) compared to obese patients (WMD, −1.06%)(p>0.05). Treatment with alpha glucosidase inhibitors in normal weight patients was associated with a HbA1c change (WMD, −0.94%) that was comparable that in overweight (WMD, −0.72%) and obese patients (WMD, −0.56%)(p>0.05). Treatment with thiazolidinediones in normal weight patients was associated with a HbA1c change (WMD, −1.04%) that was comparable with that in overweight (WMD, −1.02%) and obese patients (WMD, −0.88%)(p>0.05). Treatment with DPP-4 inhibitors in normal weight patients was associated with a HbA1c change (WMD, −0.93%) that was comparable with that in overweight (WMD, −0.66%) and obese patients (WMD, −0.61%)(p>0.05). In total, of the seven hypoglycemic agents, regression analysis indicated that the mean baseline BMI was not associated with the mean HbA1c changes from baseline. Conclusion In each kind of hypoglycemic therapy in type 2 diabetes, the baseline BMI was not associated with the efficacy of HbA1c changes from baseline. PMID:27935975

  19. Toward Robust Climate Baselining: Objective Assessment of Climate Change Using Widely Distributed Miniaturized Sensors for Accurate World-Wide Geophysical Measurements

    DOE R&D Accomplishments Database

    Teller, E.; Leith, C.; Canavan, G.; Marion, J.; Wood, L.

    2001-11-13

    A gap-free, world-wide, ocean-, atmosphere-, and land surface-spanning geophysical data-set of three decades time-duration containing the full set of geophysical parameters characterizing global weather is the scientific perquisite for defining the climate; the generally-accepted definition in the meteorological community is that climate is the 30-year running-average of weather. Until such a tridecadal climate baseline exists, climate change discussions inevitably will have a semi-speculative, vs. a purely scientific, character, as the baseline against which changes are referenced will at least somewhat uncertain.

  20. Effects of long-term treatment with testosterone on weight and waist size in 411 hypogonadal men with obesity classes I-III: observational data from two registry studies.

    PubMed

    Saad, F; Yassin, A; Doros, G; Haider, A

    2016-01-01

    Long-term testosterone replacement therapy (TRT) up to 5 years has been shown to produce progressive and sustainable weight loss (WL) in hypogonadal men. This study investigated effects of long-term TRT up to 8 years in hypogonadal men with different obesity classes. From two independent observational registries we identified a total of 411 obese, hypogonadal men receiving TRT in urological clinics. The effects of TRT on anthropometric as well as metabolic parameters were studied for a maximum duration of 8 years, mean follow-up: 6 years. All men received long-acting injections of testosterone undecanoate in 3-monthly intervals. In all three classes of obesity, T therapy produced significant WL, decrease in waist circumference (WC) and body mass index (BMI). In patients with class I obesity, mean weight decreased from 102.6±6.4 to 84.1±4.9 kg, change from baseline: -17.4±0.5 kg and -16.8±0.4%. WC in this group of patients decreased from 106.8±7.4 to 95.1±5.3 cm, change from baseline: -10.6±0.3 cm. BMI decreased from 32.69±1.4 to 27.07±1.57, change from baseline: -5.52±0.15 kg m(-2). In patients with class II obesity, weight decreased from 116.8±6.9 to 91.3±6.3 kg, change from baseline: -25.3±0.5 kg and -21.5±0.4%. WC decreased from 113.5±7.5 to 100.0±5.4 cm, change from baseline: -13.9±0.4 cm. BMI decreased from 37.32±1.45 to 29.49±1.71, change from baseline: -8.15±0.17 kg m(-2). In patients with class III obesity, weight decreased from 129.0±5.6 to 98.9±4.8 kg, change from baseline: -30.5±0.7 kg and -23.6±0.5%. WC decreased from 118.5±5.6 to 103.8±4.9 cm, change from baseline: -14.3±0.4 cm. BMI decreased from 41.93±1.48 to 32.46±1.59, change from baseline -9.96±0.29 kg m(-2). Testosterone therapy appears to be an effective approach to achieve sustained WL in obese hypogonadal men irrespective of severity of obesity. Based on these findings we suggest that T therapy offers safe and effective treatment strategy of obesity in hypogonadal men.

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