Science.gov

Sample records for basic energy science

  1. Office of Basic Energy Sciences

    NASA Astrophysics Data System (ADS)

    1991-09-01

    Basic research is an important investment in the future and will help the U.S. maintain and enhance its economic strength. The U.S. Department of Energy Office of Basic Energy Sciences (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals (energy self-sufficiency, improved health and quality of life for all, economic growth, national security) depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions. The program has two distinct interrelated parts: research and facilities operations and development. In the pursuit of forefront research results, BES designs, builds and operates certain large, complex advanced scientific facilities such as neutron sources and synchrotron radiation sources. These facilities not only provide BES with unique instruments, but these instruments are also made available to all qualified users, even those not supported by BES. Thus, the facilities actually leverage a great deal more research from the national effort. The BES program conducts basic research that will most likely help the Nation's long-term energy goals. BES implements a broad strategy for conducting basic research and contributes strongly towards national energy goals and to national goals of maintaining and enhancing scientific leadership, technological innovation, and economic strength.

  2. Basic Energy Sciences Program Update

    SciTech Connect

    None, None

    2016-01-04

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) supports fundamental research to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels to provide the foundations for new energy technologies and to support DOE missions in energy, environment, and national security. The research disciplines covered by BES—condensed matter and materials physics, chemistry, geosciences, and aspects of physical biosciences— are those that discover new materials and design new chemical processes. These disciplines touch virtually every aspect of energy resources, production, conversion, transmission, storage, efficiency, and waste mitigation. BES also plans, constructs, and operates world-class scientific user facilities that provide outstanding capabilities for imaging and spectroscopy, characterizing materials of all kinds ranging from hard metals to fragile biological samples, and studying the chemical transformation of matter. These facilities are used to correlate the microscopic structure of materials with their macroscopic properties and to study chemical processes. Such experiments provide critical insights to electronic, atomic, and molecular configurations, often at ultrasmall length and ultrafast time scales.

  3. Basic Energy Sciences FY 2011 Research Summaries

    SciTech Connect

    2011-01-01

    This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  4. Basic Energy Sciences FY 2012 Research Summaries

    SciTech Connect

    2012-01-01

    This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  5. Basic Energy Sciences FY 2014 Research Summaries

    SciTech Connect

    2014-01-01

    This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

  6. Basic Energy Sciences: Summary of Accomplishments

    DOE R&D Accomplishments Database

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy-related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user'' facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  7. Basic energy sciences: Summary of accomplishments

    NASA Astrophysics Data System (ADS)

    1990-05-01

    For more than four decades, the Department of Energy, including its predecessor agencies, has supported a program of basic research in nuclear- and energy related sciences, known as Basic Energy Sciences. The purpose of the program is to explore fundamental phenomena, create scientific knowledge, and provide unique user facilities necessary for conducting basic research. Its technical interests span the range of scientific disciplines: physical and biological sciences, geological sciences, engineering, mathematics, and computer sciences. Its products and facilities are essential to technology development in many of the more applied areas of the Department's energy, science, and national defense missions. The accomplishments of Basic Energy Sciences research are numerous and significant. Not only have they contributed to Departmental missions, but have aided significantly the development of technologies which now serve modern society daily in business, industry, science, and medicine. In a series of stories, this report highlights 22 accomplishments, selected because of their particularly noteworthy contributions to modern society. A full accounting of all the accomplishments would be voluminous. Detailed documentation of the research results can be found in many thousands of articles published in peer-reviewed technical literature.

  8. Basic Science for a Secure Energy Future

    NASA Astrophysics Data System (ADS)

    Horton, Linda

    2010-03-01

    Anticipating a doubling in the world's energy use by the year 2050 coupled with an increasing focus on clean energy technologies, there is a national imperative for new energy technologies and improved energy efficiency. The Department of Energy's Office of Basic Energy Sciences (BES) supports fundamental research that provides the foundations for new energy technologies and supports DOE missions in energy, environment, and national security. The research crosses the full spectrum of materials and chemical sciences, as well as aspects of biosciences and geosciences, with a focus on understanding, predicting, and ultimately controlling matter and energy at electronic, atomic, and molecular levels. In addition, BES is the home for national user facilities for x-ray, neutron, nanoscale sciences, and electron beam characterization that serve over 10,000 users annually. To provide a strategic focus for these programs, BES has held a series of ``Basic Research Needs'' workshops on a number of energy topics over the past 6 years. These workshops have defined a number of research priorities in areas related to renewable, fossil, and nuclear energy -- as well as cross-cutting scientific grand challenges. These directions have helped to define the research for the recently established Energy Frontier Research Centers (EFRCs) and are foundational for the newly announced Energy Innovation Hubs. This overview will review the current BES research portfolio, including the EFRCs and user facilities, will highlight past research that has had an impact on energy technologies, and will discuss future directions as defined through the BES workshops and research opportunities.

  9. FWP executive summaries: Basic energy sciences materials sciences programs

    SciTech Connect

    Samara, G.A.

    1996-02-01

    This report provides an Executive Summary of the various elements of the Materials Sciences Program which is funded by the Division of Materials Sciences, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico.

  10. 78 FR 6088 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Basic Energy Sciences, U.S. Department of Energy; SC-22/Germantown Building, 1000 Independence Avenue SW...

  11. 77 FR 5246 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. ] SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory... Perine; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown Building, 1000...

  12. 75 FR 41838 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee...; Office of Basic Energy Sciences; U.S. Department of Energy; Germantown Building, 1000 Independence Avenue...

  13. 77 FR 41395 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  14. 76 FR 48147 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of renewal of the Basic Energy Sciences Advisory Committee. SUMMARY: Pursuant to Section 14(a)(2)(A) of...

  15. 78 FR 38696 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  16. 76 FR 41234 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Basic Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory...

  17. 76 FR 8358 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Energy Sciences; U.S. Department of Energy; Germantown Building, 1000 Independence Avenue, SW...

  18. 75 FR 6369 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of Open Meeting. SUMMARY: This notice announces a meeting of the Basic Energy Sciences Advisory Committee... Energy Sciences; U.S. Department of Energy; Germantown Building, Independence Avenue, Washington, DC...

  19. 78 FR 47677 - Basic Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of... Sciences Advisory Committee's (BESAC) charter will be renewed for a two-year period. The Committee will provide advice and recommendations to the Office of Science on the Basic Energy Sciences program...

  20. Basic research supported by the Office of Basic Energy Sciences, U.S. Department of Energy

    SciTech Connect

    Kelley, R.D.

    1995-08-01

    This presentation will outline the basic research activities of the Office of Basic Energy Sciences (BES) of the U.S. Department of Energy. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department`s mission. Of particular focus in the presentation are the research programs, amounting to about $10 million, supported by the Materials Sciences Division and the Chemical Sciences Division which are fairly directly related to electrochemical technologies.

  1. Office of Basic Energy Sciences 1990 summary report

    SciTech Connect

    Not Available

    1990-10-01

    Basic research is an important investment in the future which will help the US maintain and enhance its economic strength. The Office of Basic Energy Sciences (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals -- energy self-sufficiency, improved health and quality of life for all, economic growth, national security -- depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions.

  2. Office of Basic Energy Sciences 1990 summary report

    NASA Astrophysics Data System (ADS)

    1990-10-01

    Basic research is an important investment in the future which will help the U.S. maintain and enhance its economic strength. The Office of Basic Energy Sciences' (BES) basic research activities, carried out mainly in universities and Department of Energy (DOE) laboratories, are critical to the Nation's leadership in science, for training future scientists, and to fortify the Nation's foundations for social and economic well-being. Attainment of the national goals -- energy self-sufficiency, improved health and quality of life for all, economic growth, national security -- depends on both technological research achievements and the ability to exploit them rapidly. Basic research is a necessary element for technology development and economic growth. This report presents the Department of Energy's Office of Basic Energy Sciences program. The BES mission is to develop understanding and to stimulate innovative thinking needed to fortify the Department's missions.

  3. Opportunities for Computational Discovery in Basic Energy Sciences

    NASA Astrophysics Data System (ADS)

    Pederson, Mark

    2011-03-01

    An overview of the broad-ranging support of computational physics and computational science within the Department of Energy Office of Science will be provided. Computation as the third branch of physics is supported by all six offices (Advanced Scientific Computing, Basic Energy, Biological and Environmental, Fusion Energy, High-Energy Physics, and Nuclear Physics). Support focuses on hardware, software and applications. Most opportunities within the fields of~condensed-matter physics, chemical-physics and materials sciences are supported by the Officeof Basic Energy Science (BES) or through partnerships between BES and the Office for Advanced Scientific Computing. Activities include radiation sciences, catalysis, combustion, materials in extreme environments, energy-storage materials, light-harvesting and photovoltaics, solid-state lighting and superconductivity.~ A summary of two recent reports by the computational materials and chemical communities on the role of computation during the next decade will be provided. ~In addition to materials and chemistry challenges specific to energy sciences, issues identified~include a focus on the role of the domain scientist in integrating, expanding and sustaining applications-oriented capabilities on evolving high-performance computing platforms and on the role of computation in accelerating the development of innovative technologies. ~~

  4. FWP executive summaries: basic energy sciences materials sciences and engineering program (SNL/NM).

    SciTech Connect

    Samara, George A.; Simmons, Jerry A.

    2006-07-01

    This report presents an Executive Summary of the various elements of the Materials Sciences and Engineering Program which is funded by the Division of Materials Sciences and Engineering, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico. A general programmatic overview is also presented.

  5. Opportunities for discovery: Theory and computation in Basic Energy Sciences

    SciTech Connect

    Harmon, Bruce; Kirby, Kate; McCurdy, C. William

    2005-01-11

    New scientific frontiers, recent advances in theory, and rapid increases in computational capabilities have created compelling opportunities for theory and computation to advance the scientific mission of the Office of Basic Energy Sciences (BES). The prospects for success in the experimental programs of BES will be enhanced by pursuing these opportunities. This report makes the case for an expanded research program in theory and computation in BES. The Subcommittee on Theory and Computation of the Basic Energy Sciences Advisory Committee was charged with identifying current and emerging challenges and opportunities for theoretical research within the scientific mission of BES, paying particular attention to how computing will be employed to enable that research. A primary purpose of the Subcommittee was to identify those investments that are necessary to ensure that theoretical research will have maximum impact in the areas of importance to BES, and to assure that BES researchers will be able to exploit the entire spectrum of computational tools, including leadership class computing facilities. The Subcommittee s Findings and Recommendations are presented in Section VII of this report.

  6. Basic science and energy research sector profile: Background for the National Energy Strategy

    SciTech Connect

    March, F.; Ashton, W.B.; Kinzey, B.R.; McDonald, S.C.; Lee, V.E.

    1990-11-01

    This Profile report provides a general perspective on the role of basic science in the spectrum of research and development in the United States, and basic research's contributions to the goals of the National Energy Strategy (NES). It includes selected facts, figures, and analysis of strategic issues affecting the future of science in the United States. It is provided as background for people from government, the private sector, academia, and the public, who will be reviewing the NES in the coming months; and it is intended to serve as the basis for discussion of basic science issues within the context of the developing NES.

  7. PNNL Highlights for the Office of Basic Energy Sciences (July 2013-July 2014)

    SciTech Connect

    Anderson, Benjamin; Warren, Pamela M.; Manke, Kristin L.

    2014-08-13

    This report includes research highlights of work funded in part or whole by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences as well as selected leadership accomplishments.

  8. Basic research needs to assure a secure energy future. A report from the Basic Energy Sciences Advisory Committee

    SciTech Connect

    2003-02-01

    This report has highlighted many of the possible fundamental research areas that will help our country avoid a future energy crisis. The report may not have adequately captured the atmosphere of concern that permeated the discussions at the workshop. The difficulties facing our nation and the world in meeting our energy needs over the next several decades are very challenging. It was generally felt that traditional solutions and approaches will not solve the total energy problem. Knowledge that does not exist must be obtained to address both the quantity of energy needed to increase the standard of living world-wide and the quality of energy generation needed to preserve the environment. In terms of investments, it was clear that there is no single research area that will secure the future energy supply. A diverse range of economic energy sources will be required--and a broad range of fundamental research is needed to enable these. Many of the issues fall into the traditional materials and chemical sciences research areas, but with specific emphasis on understanding mechanisms, energy related phenomena, and pursuing novel directions in, for example, nanoscience and integrated modeling. An important result from the discussions, which is hopefully apparent from the brief presentations above, is that the problems that must be dealt with are truly multidisciplinary. This means that they require the participation of investigators with different skill sets. Basic science skills have to be complemented by awareness of the overall nature of the problem in a national and world context, and with knowledge of the engineering, design, and control issues in any eventual solution. It is necessary to find ways in which this can be done while still preserving the ability to do first-class basic science. The traditional structure of research, with specific disciplinary groupings, will not be sufficient. This presents great challenges and opportunities for the funders of the

  9. Basic Science.

    ERIC Educational Resources Information Center

    Mercer County Community Coll., Trenton, NJ.

    Instructional materials are provided for a course that covers basic concepts of physics and chemistry. Designed for use in a workplace literacy project developed by Mercer County Community College (New Jersey) and its partners, the course describes applications of these concepts to real-life situations, with an emphasis on applications of…

  10. Research programs for Division of Chemical Sciences, Office of Basic Energy Sciences, Department of Energy

    SciTech Connect

    Not Available

    1988-01-01

    A chemical sciences review meeting was held in which research programs in chemistry were discussed. Major topics included: chemistry of actinides and fission products, interactions of solvents, solutes and surfaces in supercritical extraction, chemical and physical principles in multiphase separations, and chemical kinetics of enzyme catalyzed reactions. Individual projects are processed separately for the data bases. (CBS)

  11. Science for Energy Technology: Strengthening the Link Between Basic Research and Industry

    SciTech Connect

    2010-04-01

    The nation faces two severe challenges that will determine our prosperity for decades to come: assuring clean, secure, and sustainable energy to power our world, and establishing a new foundation for enduring economic and jobs growth. These challenges are linked: the global demand for clean sustainable energy is an unprecedented economic opportunity for creating jobs and exporting energy technology to the developing and developed world. But achieving the tremendous potential of clean energy technology is not easy. In contrast to traditional fossil fuel-based technologies, clean energy technologies are in their infancy, operating far below their potential, with many scientific and technological challenges to overcome. Industry is ultimately the agent for commercializing clean energy technology and for reestablishing the foundation for our economic and jobs growth. For industry to succeed in these challenges, it must overcome many roadblocks and continuously innovate new generations of renewable, sustainable, and low-carbon energy technologies such as solar energy, carbon sequestration, nuclear energy, electricity delivery and efficiency, solid state lighting, batteries and biofuels. The roadblocks to higher performing clean energy technology are not just challenges of engineering design but are also limited by scientific understanding.Innovation relies on contributions from basic research to bridge major gaps in our understanding of the phenomena that limit efficiency, performance, or lifetime of the materials or chemistries of these sustainable energy technologies. Thus, efforts aimed at understanding the scientific issues behind performance limitations can have a real and immediate impact on cost, reliability, and performance of technology, and ultimately a transformative impact on our economy. With its broad research base and unique scientific user facilities, the DOE Office of Basic Energy Sciences (BES) is ideally positioned to address these needs. BES has laid

  12. Basic Research Needs for Advanced Nuclear Systems. Report of the Basic Energy Sciences Workshop on Basic Research Needs for Advanced Nuclear Energy Systems, July 31-August 3, 2006

    SciTech Connect

    Roberto, J.; Diaz de la Rubia, T.; Gibala, R.; Zinkle, S.; Miller, J.R.; Pimblott, S.; Burns, C.; Raymond, K.; Grimes, R.; Pasamehmetoglu, K.; Clark, S.; Ewing, R.; Wagner, A.; Yip, S.; Buchanan, M.; Crabtree, G.; Hemminger, J.; Poate, J.; Miller, J.C.; Edelstein, N.; Fitzsimmons, T.; Gruzalski, G.; Michaels, G.; Morss, L.; Peters, M.; Talamini, K.

    2006-10-01

    The global utilization of nuclear energy has come a long way from its humble beginnings in the first sustained nuclear reaction at the University of Chicago in 1942. Today, there are over 440 nuclear reactors in 31 countries producing approximately 16% of the electrical energy used worldwide. In the United States, 104 nuclear reactors currently provide 19% of electrical energy used nationally. The International Atomic Energy Agency projects significant growth in the utilization of nuclear power over the next several decades due to increasing demand for energy and environmental concerns related to emissions from fossil plants. There are 28 new nuclear plants currently under construction including 10 in China, 8 in India, and 4 in Russia. In the United States, there have been notifications to the Nuclear Regulatory Commission of intentions to apply for combined construction and operating licenses for 27 new units over the next decade. The projected growth in nuclear power has focused increasing attention on issues related to the permanent disposal of nuclear waste, the proliferation of nuclear weapons technologies and materials, and the sustainability of a once-through nuclear fuel cycle. In addition, the effective utilization of nuclear power will require continued improvements in nuclear technology, particularly related to safety and efficiency. In all of these areas, the performance of materials and chemical processes under extreme conditions is a limiting factor. The related basic research challenges represent some of the most demanding tests of our fundamental understanding of materials science and chemistry, and they provide significant opportunities for advancing basic science with broad impacts for nuclear reactor materials, fuels, waste forms, and separations techniques. Of particular importance is the role that new nanoscale characterization and computational tools can play in addressing these challenges. These tools, which include DOE synchrotron X

  13. Basic Research Needs for Solar Energy Utilization. Report of the Basic Energy Sciences Workshop on Solar Energy Utilization, April 18-21, 2005

    SciTech Connect

    Lewis, N. S.; Crabtree, G.; Nozik, A. J.; Wasielewski, M. R.; Alivisatos, P.; Kung, H.; Tsao, J.; Chandler, E.; Walukiewicz, W.; Spitler, M.; Ellingson, R.; Overend, R.; Mazer, J.; Gress, M.; Horwitz, J.; Ashton, C.; Herndon, B.; Shapard, L.; Nault, R. M.

    2005-04-21

    World demand for energy is projected to more than double by 2050 and to more than triple by the end of the century. Incremental improvements in existing energy networks will not be adequate to supply this demand in a sustainable way. Finding sufficient supplies of clean energy for the future is one of society?s most daunting challenges. Sunlight provides by far the largest of all carbon-neutral energy sources. More energy from sunlight strikes the Earth in one hour (4.3 ? 1020 J) than all the energy consumed on the planet in a year (4.1 ? 1020 J). We currently exploit this solar resource through solar electricity ? a $7.5 billion industry growing at a rate of 35?40% per annum ? and solar-derived fuel from biomass, which provides the primary energy source for over a billion people. Yet, in 2001, solar electricity provided less than 0.1% of the world's electricity, and solar fuel from modern (sustainable) biomass provided less than 1.5% of the world's energy. The huge gap between our present use of solar energy and its enormous undeveloped potential defines a grand challenge in energy research. Sunlight is a compelling solution to our need for clean, abundant sources of energy in the future. It is readily available, secure from geopolitical tension, and poses no threat to our environment through pollution or to our climate through greenhouse gases. This report of the Basic Energy Sciences Workshop on Solar Energy Utilization identifies the key scientific challenges and research directions that will enable efficient and economic use of the solar resource to provide a significant fraction of global primary energy by the mid 21st century. The report reflects the collective output of the workshop attendees, which included 200 scientists representing academia, national laboratories, and industry in the United States and abroad, and the U.S. Department of Energy?s Office of Basic Energy Sciences and Office of Energy Efficiency and Renewable Energy.

  14. FWP executive summaries, Basic Energy Sciences Materials Sciences Programs (SNL/NM)

    SciTech Connect

    Samara, G.A.

    1997-05-01

    The BES Materials Sciences Program has the central theme of Scientifically Tailored Materials. The major objective of this program is to combine Sandia`s expertise and capabilities in the areas of solid state sciences, advanced atomic-level diagnostics and materials synthesis and processing science to produce new classes of tailored materials as well as to enhance the properties of existing materials for US energy applications and for critical defense needs. Current core research in this program includes the physics and chemistry of ceramics synthesis and processing, the use of energetic particles for the synthesis and study of materials, tailored surfaces and interfaces for materials applications, chemical vapor deposition sciences, artificially-structured semiconductor materials science, advanced growth techniques for improved semiconductor structures, transport in unconventional solids, atomic-level science of interfacial adhesion, high-temperature superconductors, and the synthesis and processing of nano-size clusters for energy applications. In addition, the program includes the following three smaller efforts initiated in the past two years: (1) Wetting and Flow of Liquid Metals and Amorphous Ceramics at Solid Interfaces, (2) Field-Structured Anisotropic Composites, and (3) Composition-Modulated Semiconductor Structures for Photovoltaic and Optical Technologies. The latter is a joint effort with the National Renewable Energy Laboratory. Separate summaries are given of individual research areas.

  15. A report of the Basic Energy Sciences Advisory Committee: 1992 review of the Basic Energy Sciences Program of the Department of Energy

    SciTech Connect

    Not Available

    1993-09-01

    The general quality of BES research at each of the 4 laboratories is high. Diversity of management at the different laboratories is beneficial as long as the primary BES mission and goals are clearly identified and effectively pursued. External sources of personnel should be encouraged. DOE has been designing a new high flux research reactor, the Advanced Neutron Source, to replace DOE`s two aging research reactors; BESAC conducted a panel evaluation of neutron sources for the future. The two new light sources, Advanced Light Source and Advanced Photon source will come on line well before all of their beamline instrumentation can be funded, developed, and installed. Appointment of a permanent director and deputy for OBES would enhance OBES effectiveness in budget planning and intra-DOE program coordination. Some DOE and DP laboratories have substantial infrastructure which match well industry development-applications needs; interlaboratory partnerships in this area are encouraged. Funding for basic science research programs should be maintained at FY1993 levels, adjusted for inflation; OBES plans should be updated and monitored to maintain the balance between basic research and facilities construction and operation. The recommendations are discussed in detail in this document.

  16. Use of the National Ignition Facility for defense, energy, and basic research science

    SciTech Connect

    Logan, B.G.

    1994-07-15

    On January 15, 1993, the Department of Energy (DOE) approved the Justification for Mission Need (JMN) for the National Ignition Facility (NIF). This action (Key Decision Zero, or KD0) commenced the conceptual design for the facility, which has resulted in a recently completed Conceptual Design Report (CDR). The JMN document defined the NIF mission elements to include laboratory fusion ignition and energy gain, weapons physics, and nuclear weapons effects testing research (NWET). NIF has a dual benefit by contributing to inertial fusion energy (IFE), industrial technology development, new basic science areas applying high power lasers, and training young scientists for future stewardship activities. For consideration of the next DOE action, Key Decision One (KD1), all mission elements of the NIF as stated in the JMN are consistent with and important to the US stockpile stewardship program, and are expected to continue to be in the vital interest of the United States for the long term. This document provides further information on the utility of NIF for stockpile stewardship, including support for a Comprehensive Test Ban Treaty (CTBT), and specific findings of four national workshops on the NIF utility for weapons physics, NWET, IFE and basic science research. The role of NIF for stockpile stewardship has been refined since a DOE meeting in Albuquerque, NM Feb. 1--2, 1994. The possible compliance of NIF research with anticipated CTBT and NPT limitations was discussed at the DOE Office of Arms Control and Nonproliferation in Washington, DC on March 8, 1994.

  17. Basic Science Training Program.

    ERIC Educational Resources Information Center

    Brummel, Clete

    These six learning modules were developed for Lake Michigan College's Basic Science Training Program, a workshop to develop good study skills while reviewing basic science. The first module, which was designed to provide students with the necessary skills to study efficiently, covers the following topics: time management; an overview of a study…

  18. Basic Science Training Program.

    ERIC Educational Resources Information Center

    Brummel, Clete

    These six learning modules were developed for Lake Michigan College's Basic Science Training Program, a workshop to develop good study skills while reviewing basic science. The first module, which was designed to provide students with the necessary skills to study efficiently, covers the following topics: time management; an overview of a study…

  19. Review of the Lujan neutron scattering center: basic energy sciences prereport February 2009

    SciTech Connect

    Hurd, Alan J; Rhyne, James J; Lewis, Paul S

    2009-01-01

    The Lujan Neutron Scattering Center (Lujan Center) at LANSCE is a designated National User Facility for neutron scattering and nuclear physics studies with pulsed beams of moderated neutrons (cold, thermal, and epithermal). As one of five experimental areas at the Los Alamos Neutron Science Center (LANSCE), the Lujan Center hosts engineers, scientists, and students from around the world. The Lujan Center consists of Experimental Room (ER) 1 (ERl) built by the Laboratory in 1977, ER2 built by the Office of Basic Energy Sciences (BES) in 1989, and the Office Building (622) also built by BES in 1989, along with a chem-bio lab, a shop, and other out-buildings. According to a 1996 Memorandum of Agreement (MOA) between the Defense Programs (DP) Office of the National Nuclear Security Agency (NNSA) and the Office of Science (SC, then the Office of Energy Research), the Lujan Center flight paths were transferred from DP to SC, including those in ERI. That MOA was updated in 2001. Under the MOA, NNSA-DP delivers neutron beam to the windows of the target crypt, outside of which BES becomes the 'landlord.' The leveraging nature of the Lujan Center on the LANSCE accelerator is a substantial annual leverage to the $11 M BES operating fund worth approximately $56 M operating cost of the linear accelerator (LINAC)-in beam delivery.

  20. Large Scale Computing and Storage Requirements for Basic Energy Sciences Research

    SciTech Connect

    Gerber, Richard; Wasserman, Harvey

    2011-03-31

    The National Energy Research Scientific Computing Center (NERSC) is the leading scientific computing facility supporting research within the Department of Energy's Office of Science. NERSC provides high-performance computing (HPC) resources to approximately 4,000 researchers working on about 400 projects. In addition to hosting large-scale computing facilities, NERSC provides the support and expertise scientists need to effectively and efficiently use HPC systems. In February 2010, NERSC, DOE's Office of Advanced Scientific Computing Research (ASCR) and DOE's Office of Basic Energy Sciences (BES) held a workshop to characterize HPC requirements for BES research through 2013. The workshop was part of NERSC's legacy of anticipating users future needs and deploying the necessary resources to meet these demands. Workshop participants reached a consensus on several key findings, in addition to achieving the workshop's goal of collecting and characterizing computing requirements. The key requirements for scientists conducting research in BES are: (1) Larger allocations of computational resources; (2) Continued support for standard application software packages; (3) Adequate job turnaround time and throughput; and (4) Guidance and support for using future computer architectures. This report expands upon these key points and presents others. Several 'case studies' are included as significant representative samples of the needs of science teams within BES. Research teams scientific goals, computational methods of solution, current and 2013 computing requirements, and special software and support needs are summarized in these case studies. Also included are researchers strategies for computing in the highly parallel, 'multi-core' environment that is expected to dominate HPC architectures over the next few years. NERSC has strategic plans and initiatives already underway that address key workshop findings. This report includes a brief summary of those relevant to issues

  1. [Basic science and applied science].

    PubMed

    Pérez-Tamayo, R

    2001-01-01

    A lecture was presented by the author at the Democratic Opinion Forum on Health Teaching and Research, organized by Mexico's National Health Institutes Coordinating Office, at National Cardiology Institute "Ignacio Chavez", where he presented a critical review of the conventional classification of basic and applied science, as well as his personal view on health science teaching and research. According to the author, "well-conducted science" is that "generating reality-checked knowledge" and "mis-conducted science" is that "unproductive or producing 'just lies' and 'non-fundable'. To support his views, the author reviews utilitarian and pejorative definitions of science, as well as those of committed and pure science, useful and useless science, and practical and esoterical science, as synonyms of applied and basic science. He also asserts that, in Mexico, "this classification has been used in the past to justify federal funding cutbacks to basic science, allegedly because it is not targeted at solving 'national problems' or because it was not relevant to priorities set in a given six-year political administration period". Regarding health education and research, the author asserts that the current academic programs are inefficient and ineffective; his proposal to tackle these problems is to carry out a solid scientific study, conducted by a multidisciplinary team of experts, "to design the scientific researcher curricula from recruitment of intelligent young people to retirement or death". Performance assessment of researchers would not be restricted to publication of papers, since "the quality of scientific work and contribution to the development of science is not reflected by the number of published papers". The English version of this paper is available at: http://www.insp.mx/salud/index.html

  2. Materials Sciences Programs. Fiscal Year 1980, Office of Basic Energy Sciences

    SciTech Connect

    Not Available

    1980-09-01

    This report provides a convenient compilation index of the DOE Materials Sciences Division programs. This compilation is intended for use by administrators, managers, and scientists to help coordinate research and as an aid in selecting new programs and is divided into Sections A and B, listing all the projects, Section C, a summary of funding levels, and Section D, an index (the investigator index is in two parts - laboratory and contract research).

  3. Data and Communications in Basic Energy Sciences: Creating a Pathway for Scientific Discovery

    SciTech Connect

    Nugent, Peter E.; Simonson, J. Michael

    2011-10-24

    This report is based on the Department of Energy (DOE) Workshop on “Data and Communications in Basic Energy Sciences: Creating a Pathway for Scientific Discovery” that was held at the Bethesda Marriott in Maryland on October 24-25, 2011. The workshop brought together leading researchers from the Basic Energy Sciences (BES) facilities and Advanced Scientific Computing Research (ASCR). The workshop was co-sponsored by these two Offices to identify opportunities and needs for data analysis, ownership, storage, mining, provenance and data transfer at light sources, neutron sources, microscopy centers and other facilities. Their charge was to identify current and anticipated issues in the acquisition, analysis, communication and storage of experimental data that could impact the progress of scientific discovery, ascertain what knowledge, methods and tools are needed to mitigate present and projected shortcomings and to create the foundation for information exchanges and collaboration between ASCR and BES supported researchers and facilities. The workshop was organized in the context of the impending data tsunami that will be produced by DOE’s BES facilities. Current facilities, like SLAC National Accelerator Laboratory’s Linac Coherent Light Source, can produce up to 18 terabytes (TB) per day, while upgraded detectors at Lawrence Berkeley National Laboratory’s Advanced Light Source will generate ~10TB per hour. The expectation is that these rates will increase by over an order of magnitude in the coming decade. The urgency to develop new strategies and methods in order to stay ahead of this deluge and extract the most science from these facilities was recognized by all. The four focus areas addressed in this workshop were: Workflow Management - Experiment to Science: Identifying and managing the data path from experiment to publication. Theory and Algorithms: Recognizing the need for new tools for computation at scale, supporting large data sets and realistic

  4. Reflections on basic science.

    PubMed

    Piatigorsky, Joram

    2010-01-01

    After almost 50 years in science, I believe that there is an acceptable, often advantageous chasm between open-ended basic research-free exploration without a practical destination and in which the original ideas may fade into new concepts-and translational research or clinical research. My basic research on crystalline (proteins conferring the optical properties of the eye lens) led me down paths I never would have considered if I were conducting translational research. My investigations ranged from jellyfish to mice and resulted in the gene-sharing concept, which showed that the same protein can have distinct molecular functions depending upon its expression pattern and, conversely, that different proteins can serve similar functional roles. This essay portrays basic science as a creative narrative, comparable to literary and artistic endeavors. Preserving the autonomy of open-ended basic research and recognizing its artistic, narrative qualities will accelerate the development of innovative concepts, create a rich resource of information feeding translational research, and have a positive impact by attracting creative individuals to science.

  5. Basic Energy Sciences Exascale Requirements Review. An Office of Science review sponsored jointly by Advanced Scientific Computing Research and Basic Energy Sciences, November 3-5, 2015, Rockville, Maryland

    SciTech Connect

    Clark, Aurora; Millis, Andy; Gagliardi, Laura; Panagiotopoulos, Thanos; Siepmann, Ilja; Wolverton, Chris; Vashishta, Priya; Stevens, Mark; Gordon, Mark; Kent, Paul; va DAm, Kerstin Kleese; Proffen, Thomas; Tull, Craig; Diachin, Lori; Sethian, Jamie; Benali, Anouar; Chen, Jackie; Antypas, Katie; Gerber, Richard; Riley, Katherine; Straatsma, Tjerk

    2015-12-31

    Computers have revolutionized every aspect of our lives. Yet in science, the most tantalizing applications of computing lie just beyond our reach. The current quest to build an exascale computer with one thousand times the capability of today’s fastest machines (and more than a million times that of a laptop) will take researchers over the next horizon. The field of materials, chemical reactions, and compounds is inherently complex. Imagine millions of new materials with new functionalities waiting to be discovered — while researchers also seek to extend those materials that are known to a dizzying number of new forms. We could translate massive amounts of data from high precision experiments into new understanding through data mining and analysis. We could have at our disposal the ability to predict the properties of these materials, to follow their transformations during reactions on an atom-by-atom basis, and to discover completely new chemical pathways or physical states of matter. Extending these predictions from the nanoscale to the mesoscale, from the ultrafast world of reactions to long-time simulations to predict the lifetime performance of materials, and to the discovery of new materials and processes will have a profound impact on energy technology. In addition, discovery of new materials is vital to move computing beyond Moore’s law. To realize this vision, more than hardware is needed. New algorithms to take advantage of the increase in computing power, new programming paradigms, and new ways of mining massive data sets are needed as well. This report summarizes the opportunities and the requisite computing ecosystem needed to realize the potential before us. In addition to pursuing new and more complete physical models and theoretical frameworks, this review found that the following broadly grouped areas relevant to the U.S. Department of Energy (DOE) Office of Advanced Scientific Computing Research (ASCR) would directly affect the Basic Energy

  6. Student Disaffection with Basic Science.

    ERIC Educational Resources Information Center

    Roth, Gerald I.

    1986-01-01

    Six ways to reverse student disaffection with basic science instruction are proposed, including examining the current medical model critically, changing the emphasis from facts to problem solving, decompressing the dental curriculum, building in redundancy to deepen understanding, developing applied basic science, and reexamining the changing…

  7. Basic Research Needs for Electrical Energy Storage. Report of the Basic Energy Sciences Workshop on Electrical Energy Storage, April 2-4, 2007

    DOE R&D Accomplishments Database

    Goodenough, J. B.; Abruna, H. D.; Buchanan, M. V.

    2007-04-04

    To identify research areas in geosciences, such as behavior of multiphase fluid-solid systems on a variety of scales, chemical migration processes in geologic media, characterization of geologic systems, and modeling and simulation of geologic systems, needed for improved energy systems.

  8. Basic Research Needs for Superconductivity. Report of the Basic Energy Sciences Workshop on Superconductivity, May 8-11, 2006

    SciTech Connect

    Sarrao, J.; Kwok, W-K; Bozovic, I.; Mazin, I.; Seamus, J. C.; Civale, L.; Christen, D.; Horwitz, J.; Kellogg, G.; Finnemore, D.; Crabtree, G.; Welp, U.; Ashton, C.; Herndon, B.; Shapard, L.; Nault, R. M.

    2006-05-11

    As an energy carrier, electricity has no rival with regard to its environmental cleanliness, flexibility in interfacing with multiple production sources and end uses, and efficiency of delivery. In fact, the electric power grid was named ?the greatest engineering achievement of the 20th century? by the National Academy of Engineering. This grid, a technological marvel ingeniously knitted together from local networks growing out from cities and rural centers, may be the biggest and most complex artificial system ever built. However, the growing demand for electricity will soon challenge the grid beyond its capability, compromising its reliability through voltage fluctuations that crash digital electronics, brownouts that disable industrial processes and harm electrical equipment, and power failures like the North American blackout in 2003 and subsequent blackouts in London, Scandinavia, and Italy in the same year. The North American blackout affected 50 million people and caused approximately $6 billion in economic damage over the four days of its duration. Superconductivity offers powerful new opportunities for restoring the reliability of the power grid and increasing its capacity and efficiency. Superconductors are capable of carrying current without loss, making the parts of the grid they replace dramatically more efficient. Superconducting wires carry up to five times the current carried by copper wires that have the same cross section, thereby providing ample capacity for future expansion while requiring no increase in the number of overhead access lines or underground conduits. Their use is especially attractive in urban areas, where replacing copper with superconductors in power-saturated underground conduits avoids expensive new underground construction. Superconducting transformers cut the volume, weight, and losses of conventional transformers by a factor of two and do not require the contaminating and flammable transformer oils that violate urban safety

  9. Basic sciences: an alternative career?

    PubMed

    Khatri, R

    2013-01-01

    Career selection is a crucial and a complex process which is also true for the medical profession. In the context of our country, due to the limited opportunity and proper guidance, migration of medical graduates to foreign countries is increasing. Though, clinical subjects have a huge attraction, basic science field has failed to impress our medical graduates. In current scenario, basic science field seems to be a dumping site for the incompetent as the candidates who have failed trying their luck elsewhere stumble upon basic science careers though it is not true for all. Moreover, a very few medical graduates are interested in developing their career as a basic scientist. Therefore, to motivate today's young medical graduates, there is a need of a good mentor along with a proper career guidance which can help them to understand the basic science field as an alternative career.

  10. Toward Control of Matter: Basic Energy Science Needs for a New Class of X-Ray Light Sources

    SciTech Connect

    Arenholz, Elke; Belkacem, Ali; Cocke, Lew; Corlett, John; Falcone, Roger; Fischer, Peter; Fleming, Graham; Gessner, Oliver; Hasan, M. Zahid; Hussain, Zahid; Kevan, Steve; Kirz, Janos; McCurdy, Bill; Nelson, Keith; Neumark, Dan; Nilsson, Anders; Siegmann, Hans; Stocks, Malcolm; Schafer, Ken; Schoenlein, Robert; Spence, John; Weber, Thorsten

    2008-09-24

    Over the past quarter century, light-source user facilities have transformed research in areas ranging from gas-phase chemical dynamics to materials characterization. The ever-improving capabilities of these facilities have revolutionized our ability to study the electronic structure and dynamics of atoms, molecules, and even the most complex new materials, to understand catalytic reactions, to visualize magnetic domains, and to solve protein structures. Yet these outstanding facilities still have limitations well understood by their thousands of users. Accordingly, over the past several years, many proposals and conceptual designs for"next-generation" x-ray light sources have been developed around the world. In order to survey the scientific problems that might be addressed specifically by those new light sources operating below a photon energy of about 3 keV and to identify the scientific requirements that should drive the design of such facilities, a workshop"Science for a New Class of Soft X-Ray Light Sources" was held in Berkeley in October 2007. From an analysisof the most compelling scientific questions that could be identified and the experimental requirements for answering them, we set out to define, without regard to the specific technologies upon which they might be based, the capabilities such light sources would have to deliver in order to dramatically advance the state of research in the areas represented in the programs of the Department of Energy's Office of Basic Energy Sciences (BES). This report is based on the workshop presentations and discussions.

  11. User Facilities of the Office of Basic Energy Sciences: A National Resource for Scientific Research

    SciTech Connect

    2009-01-01

    The BES user facilities provide open access to specialized instrumentation and expertise that enable scientific users from universities, national laboratories, and industry to carry out experiments and develop theories that could not be done at their home institutions. These forefront research facilities require resource commitments well beyond the scope of any non-government institution and open up otherwise inaccessible facets of Nature to scientific inquiry. For approved, peer-reviewed projects, instrument time is available without charge to researchers who intend to publish their results in the open literature. These large-scale user facilities have made significant contributions to various scientific fields, including chemistry, physics, geology, materials science, environmental science, biology, and biomedical science. Over 16,000 scientists and engineers.pdf file (27KB) conduct experiments at BES user facilities annually. Thousands of other researchers collaborate with these users and analyze the data measured at the facilities to publish new scientific findings in peer-reviewed journals.

  12. Basic science of osteoarthritis.

    PubMed

    Cucchiarini, Magali; de Girolamo, Laura; Filardo, Giuseppe; Oliveira, J Miguel; Orth, Patrick; Pape, Dietrich; Reboul, Pascal

    2016-12-01

    Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large population worldwide and for which there is no definitive cure. This review provides critical insights into the basic knowledge on OA that may lead to innovative end efficient new therapeutic regimens. While degradation of the articular cartilage is the hallmark of OA, with altered interactions between chondrocytes and compounds of the extracellular matrix, the subchondral bone has been also described as a key component of the disease, involving specific pathomechanisms controlling its initiation and progression. The identification of such events (and thus of possible targets for therapy) has been made possible by the availability of a number of animal models that aim at reproducing the human pathology, in particular large models of high tibial osteotomy (HTO). From a therapeutic point of view, mesenchymal stem cells (MSCs) represent a promising option for the treatment of OA and may be used concomitantly with functional substitutes integrating scaffolds and drugs/growth factors in tissue engineering setups. Altogether, these advances in the fundamental and experimental knowledge on OA may allow for the generation of improved, adapted therapeutic regimens to treat human OA.

  13. Basic science of pain.

    PubMed

    DeLeo, Joyce A

    2006-04-01

    The origin of the theory that the transmission of pain is through a single channel from the skin to the brain can be traced to the philosopher and scientist René Descartes. This simplified scheme of the reflex was the beginning of the development of the modern doctrine of reflexes. Unfortunately, Descartes' reflex theory directed both the study and treatment of pain for more than 330 years. It is still described in physiology and neuroscience textbooks as fact rather than theory. The gate control theory proposed by Melzack and Wall in 1965 rejuvenated the field of pain study and led to further investigation into the phenomena of spinal sensitization and central nervous system plasticity, which are the potential pathophysiologic correlates of chronic pain. The processing of pain takes place in an integrated matrix throughout the neuroaxis and occurs on at least three levels-at peripheral, spinal, and supraspinal sites. Basic strategies of pain control monopolize on this concept of integration by attenuation or blockade of pain through intervention at the periphery, by activation of inhibitory processes that gate pain at the spinal cord and brain, and by interference with the perception of pain. This article discusses each level of pain modulation and reviews the mechanisms of action of opioids and potential new analgesics. A brief description of animal models frames a discussion about recent advances regarding the role of glial cells and central nervous system neuroimmune activation and innate immunity in the etiology of chronic pain states. Future investigation into the discovery and development of novel, nonopioid drug therapy may provide needed options for the millions of patients who suffer from chronic pain syndromes, including syndromes in which the pain originates from peripheral nerve, nerve root, spinal cord, bone, muscle, and disc.

  14. High Energy Density Plasmas (HEDP) for studies of basic nuclear science relevant to Stellar and Big Bang Nucleosynthesis

    NASA Astrophysics Data System (ADS)

    Frenje, Johan

    2014-06-01

    Thermonuclear reaction rates and nuclear processes have been explored traditionally by means of conventional accelerator experiments, which are difficult to execute at conditions relevant to stellar nucleosynthesis. Thus, nuclear reactions at stellar energies are often studied through extrapolations from higher-energy data or in low-background underground experiments. Even when measurements are possible using accelerators at relevant energies, thermonuclear reaction rates in stars are inherently different from those in accelerator experiments. The fusing nuclei are surrounded by bound electrons in accelerator experiments, whereas electrons occupy mainly continuum states in a stellar environment. Nuclear astrophysics research will therefore benefit from an enlarged toolkit for studies of nuclear reactions. In this presentation, we report on the first use of High Energy Density Plasmas for studies of nuclear reactions relevant to basic nuclear science, stellar and Big Bang nucleosynthesis. These experiments were carried out at the OMEGA laser facility at University of Rochester and the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory, in which spherical capsules were irradiated with powerful lasers to compress and heat the fuel to high enough temperatures and densities for nuclear reactions to occur. Four experiments will be highlighted in this presentation. In the first experiment, the differential cross section for the elastic neutron-triton (n-T) scattering at 14.1 MeV was measured with significantly higher accuracy than achieved in accelerator experiments. In the second experiment, the T(t,2n)4He reaction, a mirror reaction to the 3He(3He,2p)4He reaction that plays an important role in the proton-proton chain that transforms hydrogen into ordinary 4He in stars like our Sun, was studied at energies in the range 15-40 keV. In the third experiment, the 3He+3He solar fusion reaction was studied directly, and in the fourth experiment, we

  15. Medical Computing: Another Basic Science?

    PubMed Central

    Shortliffe, Edward H.

    1980-01-01

    Medical computing is frequently viewed as the application of established computer science techniques in medical domains. However, it is the thesis of this paper that many clinical computing tasks demand techniques that are as yet undeveloped. As a result, medical computing research should logically be closely tied to basic research in computer science. Failure to recognize that this developing discipline often requires fundamental investigation has tended to foster unrealistic expectations of the field.

  16. Fusion connection: contributions to industry, defense, and basic science resulting from scientific advances made in the Magnetic Fusion Energy Program

    SciTech Connect

    Finn, T.; Woo, J.; Temkin, R.; Anderson, D.; Anderson, J.; Barbosa, D.; Briggs, R.; Callen, J.; Colgate, S.; Cowles, J.

    1985-10-01

    Fusion research has led to significant contributions in many different areas of industry, defense, and basic science. This diversity is represented visually in the introductory figure which shows both a radio galaxy, and a microchip produced by plasma etching. Some of these spin-off technologies are discussed.

  17. Proposal to DOE Basic Energy Sciences: Ultrafast X-ray science facility at the Advanced Light Source

    SciTech Connect

    Schoenlein, Robert W.; Falcone, Roger W.; Abela, R.; Alivisatos, A.P.; Belkacem, A.; Berrah, N.; Bozek, J.; Bressler, C.; Cavalleri, A.; Chergui, M.; Glover, T.E.; Heimann, P.A.; Hepburn, J.; Larsson, J.; Lee, R.W.; McCusker, J.; Padmore, H.A.; Pattison, P.; Pratt, S.T.; Shank, C.V.; Wark, J.; Chang, Z.; Robin, D.W.; Schlueter, R.D.; Zholents, A.A.; Zolotorev, M.S.

    2001-12-12

    We propose to develop a true user facility for ultrafast x-ray science at the Advanced Light Source. This facility will be unique in the world, and will fill a critical need for the growing ultrafast x-ray research community. The development of this facility builds upon the expertise from long-standing research efforts in ultrafast x-ray spectroscopy and the development of femtosecond x-ray sources and techniques at both the Lawrence Berkeley National Laboratory and at U.C. Berkeley. In particular, the technical feasibility of a femtosecond x-ray beamline at the ALS has already been demonstrated, and existing ultrafast laser technology will enable such a beamline to operate near the practical limit for femtosecond x-ray flux and brightness from a 3rd generation synchrotron.

  18. CROI 2016: Basic Science Review.

    PubMed

    Stevenson, Mario

    2016-01-01

    The 2016 Conference on Retroviruses and Opportunistic Infections continued to maintain balance in the representation of different areas of research related to HIV/AIDS. The basic science category encompasses research on viral reservoirs and HIV cure, on cellular factors regulating the interplay between virus and host, and on factors that influence viral pathogenicity. Basic research on factors that influence the interaction between the virus and the host cell continues to unearth surprises with the identification of a new host antiviral factor. Further, research into the mechanisms of viral persistence reveals that there is much to learn about how HIV-1 is able to persist in the face of antiviral suppression.

  19. Basic Science and The NIH

    PubMed Central

    Varmus, Harold

    1994-01-01

    The following is an edited version of the Keynote Speech delivered at the Annual Meeting of the American Society for Cell Biology by Harold Varmus, Director of the National Institutes of Health. The address, entitled Basic Science and the NIH, was given at the opening of the meeting in New Orleans on December 11, 1993. It was Varmus' first public policy talk as NIH Director. PMID:8049519

  20. Basic sciences agonize in Turkey!

    NASA Astrophysics Data System (ADS)

    Akdemir, Fatma; Araz, Asli; Akman, Ferdi; Durak, Rıdvan

    2016-04-01

    In this study, changes from past to present in the departments of physics, chemistry, biology and mathematics, which are considered as the basic sciences in Turkey, are shown. The importance of basic science for the country emphasized and the status of our country was discussed with a critical perspective. The number of academic staff, the number of students, opened quotas according to years for these four departments at universities were calculated and analysis of the resulting changes were made. In examined graphics changes to these four departments were similar. Especially a significant change was observed in the physics department. Lack of jobs employing young people who have graduated from basic science is also an issue that must be discussed. There are also qualitative results of this study that we have discussed as quantitative. Psychological problems caused by unemployment have become a disease among young people. This study was focused on more quantitative results. We have tried to explain the causes of obtained results and propose solutions.

  1. Graduate student theses supported by Carbon Dioxide Research Division, Office of Basic Energy Sciences, US Department of Energy

    SciTech Connect

    Millemann, R.E.

    1987-09-01

    The US Department of Energy's Carbon Dioxide Research Division (CDRD) has a strong commitment to support graduate education. The purpose of this report was to summarize information on thesis research supported by CDRD and to make it available to carbon dioxide researchers and other interested persons. To date, 25 Ph.D. and 23 Master's theses, including 4 internship reports for the M.En. degree from Miami University, have been written based on research supported in whole or in part by CDRD funds. Of these, 16 are in the Carbon Cycle area, 11 relate to Climate, 17 to Vegetation Response, 3 to Sea Level, and 4 pertain to the Carbon Dioxide Information and Analysis Center with a few theses relevant to more than one area. The following four lists appear in this report: An Author List with the complete thesis citation, names of the major professor, major department, and contractor, and contract number. A Contractor List with the affiliation of each contractor and the thesis research supported by that contractor. A Program Area List with the theses grouped by subject area. Finally, a University List with the theses grouped by the degree-granting institutions.

  2. Resource Handbook--Matter and Energy. A Supplement to Basic Curriculum Guide--Science, Grades K-6.

    ERIC Educational Resources Information Center

    Starr, John W., 3rd., Ed.

    GRADES OR AGES: Grades K-6. SUBJECT MATTER: Science; matter and energy. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into the following six units: 1) Composition of Matter, with 27 concepts; 2) Light, with 20 concepts; 3) Heat, with 14 concepts; 4) Sound, with 12 concepts; 5) Electricity and Magnetism, with 17 concepts; and 6)…

  3. CROI 2014: Basic science review.

    PubMed

    Stevenson, Mario

    2014-05-01

    In the HIV basic science categories of the 2014 Conference on Retroviruses and Opportunistic Infections, research examining obstacles to viral eradication continued to be a major component. This research encompassed areas of activity from the identification of where virus resides in individuals on suppressive antiretroviral therapy to studies aimed at eliminating long-lived viral reservoirs that persist in the face of therapy. In the area of antiviral restrictions, a number of presentations highlighted the ability of host factors to profoundly shape the interplay between virus and host and, in particular, how innate immune response opposes viral infection through the induction of antiviral restrictions.

  4. Basic science and treatment innovation.

    PubMed

    Green, Jonathan

    2017-09-01

    The idea of trans-diagnostic and modular treatments highlighted in this Editorial points the way beyond self-contained 'branded' therapies to a more flexible intervention science responsive to advances in basic science and relevant also to personalisation of therapies. For such approaches to be rigorous, there need to be empirically identified trans-diagnostic target mechanisms. The Editorial reviews two studies of potential mechanisms of this kind in the developmental neurobiology of stress response in children at risk from prenatal maternal stress and post natal neglect and maltreatment. A number of treatment trials are also reviewed illustrating the common method of digitally-aided therapy; a common theme is the difficult in sustaining adherence to such treatment delivery methods. Finally it reviews a useful independent investigation of a commonly used autism screening instrument, suggesting improvements for greater specificity. © 2017 Association for Child and Adolescent Mental Health.

  5. Annual report, Basic Sciences Branch, FY 1991

    SciTech Connect

    Not Available

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  6. Basic Research Needs for Solid-State Lighting. Report of the Basic Energy Sciences Workshop on Solid-State Lighting, May 22-24, 2006

    SciTech Connect

    Phillips, J. M.; Burrows, P. E.; Davis, R. F.; Simmons, J. A.; Malliaras, G. G.; So, F.; Misewich, J.A.; Nurmikko, A. V.; Smith, D. L.; Tsao, J. Y.; Kung, H.; Crawford, M. H.; Coltrin, M. E.; Fitzsimmons, T. J.; Kini, A.; Ashton, C.; Herndon, B.; Kitts, S.; Shapard, L.; Brittenham, P. W.; Vittitow, M. P.

    2006-05-24

    The workshop participants enthusiastically concluded that the time is ripe for new fundamental science to beget a revolution in lighting technology. SSL sources based on organic and inorganic materials have reached a level of efficiency where it is possible to envision their use for general illumination. The research areas articulated in this report are targeted to enable disruptive advances in SSL performance and realization of this dream. Broad penetration of SSL technology into the mass lighting market, accompanied by vast savings in energy usage, requires nothing less. These new ?good ideas? will be represented not by light bulbs, but by an entirely new lighting technology for the 21st century and a bright, energy-efficient future indeed.

  7. CROI 2013: Basic science review.

    PubMed

    Stevenson, Mario

    2013-01-01

    The 20th Conference on Retroviruses and Opportunistic Infections was held in Atlanta, Georgia, and featured strong coverage in several basic science categories. Presentations on viral reservoir and cure research covered a variety of topics, including approaches to gauge viral reservoir size in patients on suppressive antiretroviral therapy, approaches to reactivate latently infected cells, and the role of residual replication in viral persistence under antiretroviral therapy. Research on viral restriction factors remains a strong feature of the conference, and presentations on the impact of viral restrictions on the establishment of viral reservoirs, as well as strategies that harness the antiviral potential of cellular restrictions, generated a lot of interest. Several studies on the nature of proviral latency left us with the sobering message that elimination of the latent viral pool is going to be an even greater challenge than previously suspected.

  8. CROI 2015: Basic Science Review.

    PubMed

    Stevenson, Mario

    2015-01-01

    The 2015 Conference on Retroviruses and Opportunistic Infections (CROI) represents a forum that encompasses all facets of research on HIV/AIDS and its complications. CROI is a valuable venue for scientific and public health researchers, clinicians, policy makers, and community representatives to be updated on the latest advances in their specific areas of interest and beyond. CROI 2015 continued to surprise. New insights into the viral reservoirs that persist in the face of antiretroviral therapy were prominently featured, as were therapeutic approaches aimed at curtailing and eliminating persistent viral reservoirs in HIV-infected individuals. Basic science is providing surrogates that could be valuable in how viral reservoirs are measured and, ultimately, in how to gauge if they are being effectively eliminated.

  9. Annual report, Basic Sciences Branch, FY 1991

    SciTech Connect

    Not Available

    1993-04-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1990, through September 30, 1991. Seven technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, Solid-State Spectroscopy, and Superconductivity. Each section explains the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  10. Basic space sciences in Africa

    NASA Astrophysics Data System (ADS)

    Abiodun, Adigun Ade; Odingo, Richard S.

    Through space applications, a number of social and economic programmes in education, communications, agro-climatology, weather forecasting and remote sensing are being realized within the African continent. Regional and international organizations and agencies such as the African Remote Sensing Council, the Pan-African Telecommunication Union and the United Nations system have been instrumental in making Africa conscious of the impact and implications of space science and technology on its peoples. The above notwithstanding, discernible interests in space research, to date, in Africa, have been limited to the work on the solar system and on interplanetary matters including satellite tracking, and to the joint African-Indian proposal for the establishment of an International Institute for Space Sciences and Electronics (INISSE) and the construction, in Kenya, of a Giant Equatorial Radio Telescope (GERT). During this ``Transport and Communications Decade in Africa,'' Africa's basic space research efforts would need to initially focus on the appropriateness, modification and adaptation of existing technologies for African conditions with a view to providing economic, reliable and functional services for the continent. These should include elements of electronics, communications, structural and tooling industries, and upper-atmosphere research. The experience of and collaborative work with India, Brazil and Argentina, as well as the roles of African scientists, are examined.

  11. Basic Sciences Branch annual report, FY 1990

    SciTech Connect

    Not Available

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL`s in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy`s National Photovoltaic Research Program plans.

  12. Symmetry in the basic sciences

    NASA Astrophysics Data System (ADS)

    Toole, Joseph E.; Jensen, David W.; Rogers, Mark E.; Chernek, Paul J.; Erstfeld, Thomas E.

    1989-04-01

    The basic mathematical theory behind plane symmetry groups is presented. This theory is then applied in classifying the symmetry of bounded figures, frieze patterns and wallpaper patterns. Recently developed algorithms are included to help analyze complex designs. Symmetry operations relevant to 3-D crystallography are discussed. In particular, the seven crystal systems that classify the 32 crystallographic point groups are described. These are then used to construct the Bravais lattices. The role is investigated of symmetry in biological forms. Specifically, work on growth and form of molluscan shells is reviewed with an attempt to explain the consequences of that growth and form to the natural history of the Chambered Nautilus and its ancestors. The central role symmetry has increasingly played in physics is looked at by examining the Principle of Least Action and the invariance of the Lagrangian under a transformation. Noether's Theorem guarantees that a conservation law is associated with each of these symmetries. Examples include the conservation of energy, linear momentum, and angular momentum, as well as the purely quantum mechanical symmetry of invariance under an exchange operation. A brief look at gauge theories is the final example of how symmetry has become a guiding principle in the formulation of new theories.

  13. Basic Research Needs for the Hydrogen Economy. Report of the Basic Energy Sciences Workshop on Hydrogen Production, Storage and Use, May 13-15, 2003

    SciTech Connect

    Dresselhaus, M; Crabtree, G; Buchanan, M; Mallouk, T; Mets, L; Taylor, K; Jena, P; DiSalvo, F; Zawodzinski, T; Kung, H; Anderson, I S; Britt, P; Curtiss, L; Keller, J; Kumar, R; Kwok, W; Taylor, J; Allgood, J; Campbell, B; Talamini, K

    2004-02-01

    The coupled challenges of a doubling in the world's energy needs by the year 2050 and the increasing demands for ''clean'' energy sources that do not add more carbon dioxide and other pollutants to the environment have resulted in increased attention worldwide to the possibilities of a ''hydrogen economy'' as a long-term solution for a secure energy future.

  14. Basic Sciences Branch annual report, FY 1990

    SciTech Connect

    Not Available

    1991-12-01

    This report summarizes the progress of the Basic Sciences Branch of the National Renewable Energy Laboratory (NREL) from October 1, 1989, through September 30, 1990. Six technical sections of the report cover these main areas of NREL's in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Solid-State Spectroscopy. Each section of the report was written by the group leader principally in charge of the work. The task in each case was to explain the purpose and major accomplishments of the work in the context of the US Department of Energy's National Photovoltaic Research Program plans.

  15. Scientific Grand Challenges: Discovery In Basic Energy Sciences: The Role of Computing at the Extreme Scale - August 13-15, 2009, Washington, D.C.

    SciTech Connect

    Galli, Giulia; Dunning, Thom

    2009-08-13

    The U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) and Office of Advanced Scientific Computing Research (ASCR) workshop in August 2009 on extreme-scale computing provided a forum for more than 130 researchers to explore the needs and opportunities that will arise due to expected dramatic advances in computing power over the next decade. This scientific community firmly believes that the development of advanced theoretical tools within chemistry, physics, and materials science—combined with the development of efficient computational techniques and algorithms—has the potential to revolutionize the discovery process for materials and molecules with desirable properties. Doing so is necessary to meet the energy and environmental challenges of the 21st century as described in various DOE BES Basic Research Needs reports. Furthermore, computational modeling and simulation are a crucial complement to experimental studies, particularly when quantum mechanical processes controlling energy production, transformations, and storage are not directly observable and/or controllable. Many processes related to the Earth’s climate and subsurface need better modeling capabilities at the molecular level, which will be enabled by extreme-scale computing.

  16. Clinical Science-linking basic science to disease mechanisms.

    PubMed

    Touyz, Rhian M

    2017-04-01

    For more than 50 years, Clinical Science has been at the interface linking basic science to disease mechanisms. Here, Rhian Touyz, the Editor-in-Chief, describes the journal, its aims and scope, and recent developments.

  17. Science versus Basic Educational Research

    ERIC Educational Resources Information Center

    Engelmann, Siegfried

    2008-01-01

    One goal of basic research in education is to identify the variables of effective instruction. As this pursuit has been conceived, however, its theoretical problems make it unlikely that the effort will provide a clear picture of instructional variables, their interactions, or the kind of teacher training that is implied by instructional variables.

  18. CROI 2017: Basic Science Review.

    PubMed

    Stevenson, Mario

    The Conference on Retroviruses and Opportunistic Infections (CROI) continues to be the preeminent gathering for HIV/AIDS researchers. It provides a forum in which investigators involved in all aspects of research on HIV/AIDS and related conditions can present and be updated on the latest scientific developments in the field. In 2017, basic research continued to be strongly represented at the conference. Most of the presentations focused on mechanisms of viral persistence in the face of effective antiretroviral therapy as well as approaches to measuring viral reservoirs and intervening in those reservoirs. The intermix of basic and clinical research presentations provided a dynamic forum for the sharing of knowledge that is crucial to moving the field forward.

  19. Hurdles in Basic Science Translation.

    PubMed

    Perry, Christina J; Lawrence, Andrew J

    2017-01-01

    In the past century there have been incredible advances in the field of medical research, but what hinders translation of this knowledge into effective treatment for human disease? There is an increasing focus on the failure of many research breakthroughs to be translated through the clinical trial process and into medical practice. In this mini review, we will consider some of the reasons that findings in basic medical research fail to become translated through clinical trials and into basic medical practices. We focus in particular on the way that human disease is modeled, the understanding we have of how our targets behave in vivo, and also some of the issues surrounding reproducibility of basic research findings. We will also look at some of the ways that have been proposed for overcoming these issues. It appears that there needs to be a cultural shift in the way we fund, publish and recognize quality control in scientific research. Although this is a daunting proposition, we hope that with increasing awareness and focus on research translation and the hurdles that impede it, the field of medical research will continue to inform and improve medical practice across the world.

  20. Radiological Dispersion Devices and Basic Radiation Science

    ERIC Educational Resources Information Center

    Bevelacqua, Joseph John

    2010-01-01

    Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous…

  1. Radiological Dispersion Devices and Basic Radiation Science

    ERIC Educational Resources Information Center

    Bevelacqua, Joseph John

    2010-01-01

    Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous…

  2. Basic Principles of Animal Science. Reprinted.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    The reference book is designed to fulfill the need for organized subject matter dealing with basic principles of animal science to be incorporated into the high school agriculture curriculum. The material presented is scientific knowledge basic to livestock production. Five units contain specific information on the following topics: anatomy and…

  3. [Challenges of basical sciences in medical education].

    PubMed

    Rodríguez Carranza, Rodolfo

    2014-12-01

    The relevance of basic sciences in medical education has been recognized for centuries, and the importance of exposing medical students to science was acknowledged and reinforced by the recommendations of Flexner in 1910. Since then, traditional medical education has been divided into preclinical and clinical subjects; within this scheme, the first terms of undergraduate medical education usually concentrate on basic sciences, while subsequent ones focus on clinical sciences and clinical training. Since 1956, this educational scheme has been questioned and, in some schools, the medical curriculum has undergone significant structural changes; some of these reforms, especially integrated curricula, are associated with important reductions in the time allotted to individual basic science courses or even with their removal. The removal of basic science subjects from the medical curriculum is paradoxical because nowadays the value of biomedical knowledge and the scientific reasoning to make medical decisions is more appreciated than ever. To maintain its relevance in medical education, basic sciences have to confront three challenges: a) increasing its presence in clinical education; b) developing nuclear programs; and c) renewing laboratory instruction.

  4. Fusion Energy Sciences Network Requirements

    SciTech Connect

    Dart, Eli; Tierney, Brian

    2012-09-26

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 25 years. In December 2011, ESnet and the Office of Fusion Energy Sciences (FES), of the DOE Office of Science (SC), organized a workshop to characterize the networking requirements of the programs funded by FES. The requirements identified at the workshop are summarized in the Findings section, and are described in more detail in the body of the report.

  5. Translating orthopaedic basic science into clinical relevance.

    PubMed

    Madry, Henning

    2014-12-01

    In orthopaedic and trauma surgery, the rapid evolution of biomedical research has fundamentally changed the perception of the musculoskeletal system. Here, the rigor of basic science and the art of musculoskeletal surgery have come together to create a new discipline -experimental orthopaedics- that holds great promise for the causative cure of many orthopaedic conditions. The Journal of Experimental Orthopaedics intends to bridge the gap between orthopaedic basic science and clinical relevance, to allow for a fruitful clinical translation of excellent and important investigations in the field of the entire musculoskeletal system.

  6. Basic science and applied science instruction: are they compatible?

    PubMed

    Harmon, B G

    1992-08-01

    Basic science and applied science instruction are compatible and essential for animal science professionals to succeed in their chosen career. Application of science is a continuum. Although production methods are constantly evolving, the science on which changes are made is fixed and fundamental. Only our understanding changes. We are educating students in preparation for a life-long learning process. Viability of animal science departments depends on attracting and challenging students with curricula that are demanding, create curiosity, and prepare students to understand the "whys and hows" of the phenomena of animal biology.

  7. Basic science right, not basic science lite: medical education at a crossroad.

    PubMed

    Fincher, Ruth-Marie E; Wallach, Paul M; Richardson, W Scott

    2009-11-01

    This perspective is a counterpoint to Dr. Brass' article, Basic biomedical sciences and the future of medical education: implications for internal medicine. The authors review development of the US medical education system as an introduction to a discussion of Dr. Brass' perspectives. The authors agree that sound scientific foundations and skill in critical thinking are important and that effective educational strategies to improve foundational science education should be implemented. Unfortunately, many students do not perceive the relevance of basic science education to clinical practice.The authors cite areas of disagreement. They believe it is unlikely that the importance of basic sciences will be diminished by contemporary directions in medical education and planned modifications of USMLE. Graduates' diminished interest in internal medicine is unlikely from changes in basic science education.Thoughtful changes in education provide the opportunity to improve understanding of fundamental sciences, the process of scientific inquiry, and translation of that knowledge to clinical practice.

  8. Preparation of Basic and Clinical Sciences Faculty.

    ERIC Educational Resources Information Center

    Adams, Anthony J.

    1995-01-01

    A discussion of basic and clinical science teaching in optometry in the next decade looks at the changing role of primary care and specialist optometrists, the training needs of current and future faculty, recommended curriculum changes, and decision making about delivery of this training. The roles of graduate training, residencies, and…

  9. Integration of Basic Sciences in Health's Courses

    ERIC Educational Resources Information Center

    Azzalis, L. A.; Giavarotti, L.; Sato, S. N.; Barros, N. M. T.; Junqueira, V. B. C.; Fonseca, F. L. A.

    2012-01-01

    Concepts from disciplines such as Biochemistry, Genetics, Cellular and Molecular Biology are essential to the understanding and treatment of an elevated number of illnesses, but often they are studied separately, with no integration between them. This article proposes a model for basic sciences integration based on problem-based learning (PBL) and…

  10. Integration of Basic Sciences in Health's Courses

    ERIC Educational Resources Information Center

    Azzalis, L. A.; Giavarotti, L.; Sato, S. N.; Barros, N. M. T.; Junqueira, V. B. C.; Fonseca, F. L. A.

    2012-01-01

    Concepts from disciplines such as Biochemistry, Genetics, Cellular and Molecular Biology are essential to the understanding and treatment of an elevated number of illnesses, but often they are studied separately, with no integration between them. This article proposes a model for basic sciences integration based on problem-based learning (PBL) and…

  11. Basic Physical Science. Apprentice Related Training Module.

    ERIC Educational Resources Information Center

    Rice, Eric

    One in a series of core instructional materials for apprentices to use during the first or second years of apprentice-related subjects training, this booklet deals with basic physical science. The first section consists of an outline of the content and scope of the core materials as well as a self-assessment pretest. Covered in the four…

  12. Radiological Dispersion Devices and Basic Radiation Science

    NASA Astrophysics Data System (ADS)

    Bevelacqua, Joseph John

    2010-05-01

    Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous manner. One reason for limited student interest is the failure to link the discussion to topics of current interest. The author has found that presenting this material with a link to radiological dispersion devices (RDDs), or dirty bombs, and their associated health effects provides added motivation for students. The events of Sept. 11, 2001, and periodic media focus on RDDs heighten student interest from both a scientific curiosity as well as a personal protection perspective. This article presents a framework for a more interesting discussion of the basics of radiation science and their associated health effects. The presentation can be integrated with existing radioactivity lectures or added as a supplementary or enrichment activity.

  13. Integrative basic sciences: change in mental status.

    PubMed

    Crane, Erika; Clark, Jeff

    2009-04-01

    This case discussion is part of the Integrating Basic Science Into Clinical Teaching Initiative. It examines the presentation of altered mental status and describes the underlying physiology, which explains the basic laboratory findings in an attempt to reach a diagnosis. This article describes a 13-year-old boy who presented to the emergency department with altered mental status after being found unconscious and alone in an abandoned building. He was unresponsive to painful and verbal stimuli, with otherwise normal findings on physical examination. Basic laboratory studies, including arterial blood gas, electrolytes, and serum osmolality, were obtained. The case discussion uses fundamentals of anatomy to build a focused differential diagnosis. The laboratory studies are interpreted using basic physiologic principles, including acid-base balance, anion gap, and osmolar gap, to determine the most likely cause of this patient's altered mental status. Subsequent investigation confirms a diagnosis of ethanol toxic effects. An understanding of electrolyte and acid-base physiology allows the clinician to use basic laboratory studies to build a focused differential diagnosis for altered mental status. This case discussion demonstrates how basic science principles of anatomy and physiology can be applied in clinical settings.

  14. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, Hans; Balogh, Werner

    2014-05-01

    The basic space science initiative was a long-term effort for the development of astronomy and space science through regional and international cooperation in this field on a worldwide basis, particularly in developing nations. Basic space science workshops were co-sponsored and co-organized by ESA, JAXA, and NASA. A series of workshops on basic space science was held from 1991 to 2004 (India 1991, Costa Rica and Colombia 1992, Nigeria 1993, Egypt 1994, Sri Lanka 1995, Germany 1996, Honduras 1997, Jordan 1999, France 2000, Mauritius 2001, Argentina 2002, and China 2004; http://neutrino.aquaphoenix.com/un-esa/) and addressed the status of astronomy in Asia and the Pacific, Latin America and the Caribbean, Africa, and Western Asia. Through the lead of the National Astronomical Observatory Japan, astronomical telescope facilities were inaugurated in seven developing nations and planetariums were established in twenty developing nations based on the donation of respective equipment by Japan.Pursuant to resolutions of the Committee on the Peaceful Uses of Outer Space of the United Nations (COPUOS) and its Scientific and Technical Subcommittee, since 2005, these workshops focused on the preparations for and the follow-ups to the International Heliophysical Year 2007 (UAE 2005, India 2006, Japan 2007, Bulgaria 2008, South Korea 2009; www.unoosa.org/oosa/SAP/bss/ihy2007/index.html). IHY's legacy is the current operation of 16 worldwide instrument arrays with more than 1000 instruments recording data on solar-terrestrial interaction from coronal mass ejections to variations of the total electron content in the ionosphere (http://iswisecretariat.org/). Instruments are provided to hosting institutions by entities of Armenia, Brazil, France, Israel, Japan, Switzerland, and the United States. Starting in 2010, the workshops focused on the International Space Weather Initiative (ISWI) as mandated in a three-year-work plan as part of the deliberations of COPUOS. Workshops on ISWI

  15. Basic science research in Australian intensive care practice.

    PubMed

    Laurie, Gordon A; Venkatesh, Bala; Kruger, Peter S; Morgan, T John; Pascoe, Ranald L S

    2008-03-01

    A number of recent therapeutic advances have resulted from basic science research. With the change in medical education and practice towards evidence-based medicine, we wished to determine the role of basic science research in Australian intensive care practice. We believe this is the first survey of Australian intensivists and trainees to assess the influence of basic science research on their clinical duties. We discuss the importance and influence of basic science in intensive care practice and the development of postgraduate appreciation of basic science, highlight the impact of some of the changes in medical education on basic science undergraduate teaching, and discuss the clinical applicability and current participation in basic science research. A questionnaire was mailed in November 2006 to all registered Fellows and trainees of the Joint Faculty of Intensive Care Medicine who were resident in Australia. 267 of 801 surveys were returned (33% response rate): 74% of respondents believed basic science is an important or very important influence on clinical decision-making, which is consistent with previous studies, and 8% believed it is crucial. The most familiar areas of basic science research are those with established clinical applications, such as drug metabolism, regional perfusion and the complement cascade. Most current intensive care practitioners were taught basic science as undergraduates. Involvement in basic science research increases during intensive care training, from 10% before a medical degree to over 30% at the end of training, with over a quarter of practicing intensivists having a basic science degree. Despite this increase in interest during training, only 9% of journal club attendees reported that they discuss basic science articles. Critical care practitioners consider basic science research to be relevant and important to their practice. There is interest in clinically applicable basic science research, but few people regularly review

  16. Limitations on diversity in basic science departments.

    PubMed

    Leboy, Phoebe S; Madden, Janice F

    2012-08-01

    It has been over 30 years since the beginning of efforts to improve diversity in academia. We can identify four major stages: (1) early and continuing efforts to diversify the pipeline by increasing numbers of women and minorities getting advanced degrees, particularly in science, technology, engineering, and math (STEM); (2) requiring academic institutions to develop their own "affirmative action plans" for hiring and promotion; (3) introducing mentoring programs and coping strategies to help women and minorities deal with faculty practices from an earlier era; (4) asking academic institutions to rethink their practices and policies with an eye toward enabling more faculty diversity, a process known as institutional transformation. The thesis of this article is that research-intensive basic science departments of highly ranked U.S. medical schools are stuck at stage 3, resulting in a less diverse tenured and tenure-track faculty than seen in well-funded science departments of major universities. A review of Web-based records of research-intensive departments in universities with both medical school and nonmedical school departments indicates that the proportion of women and Black faculty in science departments of medical schools is lower than the proportion in similarly research-intensive university science departments. Expectations for faculty productivity in research-intensive medical school departments versus university-based departments may lead to these differences in faculty diversity.

  17. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    Pursuant to recommendations of the United Nations Conference on the Exploration and Peaceful Uses of Outer Space UNISPACE III and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space UNCOPUOS annual UN European Space Agency workshops on basic space science have been held around the world since 1991 These workshops contribute to the development of astrophysics and space science particularly in developing nations Following a process of prioritization the workshops identified the following elements as particularly important for international cooperation in the field i operation of astronomical telescope facilities implementing TRIPOD ii virtual observatories iii astrophysical data systems iv concurrent design capabilities for the development of international space missions and v theoretical astrophysics such as applications of nonextensive statistical mechanics Beginning in 2005 the workshops focus on preparations for the International Heliophysical Year 2007 IHY2007 The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost ground-based world-wide instrument arrays as lead by the IHY secretariat Further information Wamsteker W Albrecht R and Haubold H J Developing Basic Space Science World-Wide A Decade of UN ESA Workshops Kluwer Academic Publishers Dordrecht 2004 http ihy2007 org http www oosa unvienna org SAP bss ihy2007 index html http www cbpf br GrupPesq StatisticalPhys biblio htm

  18. The United Nations Basic Space Science Initiative

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    2006-08-01

    Pursuant to recommendations of the United Nations Conference on the Exploration and Peaceful Uses of Outer Space (UNISPACE III) and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS), annual UN/ European Space Agency workshops on basic space science have been held around the world since 1991. These workshops contribute to the development of astrophysics and space science, particularly in developing nations. Following a process of prioritization, the workshops identified the following elements as particularly important for international cooperation in the field: (i) operation of astronomical telescope facilities implementing TRIPOD, (ii) virtual observatories, (iii) astrophysical data systems, (iv) concurrent design capabilities for the development of international space missions, and (v) theoretical astrophysics such as applications of nonextensive statistical mechanics. Beginning in 2005, the workshops focus on preparations for the International Heliophysical Year 2007 (IHY2007). The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost, ground-based, world-wide instrument arrays as lead by the IHY secretariat. Wamsteker, W., Albrecht, R. and Haubold, H.J.: Developing Basic Space Science World-Wide: A Decade of UN/ESA Workshops. Kluwer Academic Publishers, Dordrecht 2004. http://ihy2007.org http://www.unoosa.org/oosa/en/SAP/bss/ihy2007/index.html http://www.cbpf.br/GrupPesq/StatisticalPhys/biblio.htm

  19. Office of Basic Energy Sciences program to meet high priority nuclear data needs of the Office of Fusion Energy 1983 review

    SciTech Connect

    Haight, R.C.; Larson, D.C.

    1983-11-01

    This review was prepared during a coordination meeting held at Oak Ridge National Laboratory on September 28-29, 1983. Participants included research scientists working for this program, a representative from the OFE's Coordination of Magnetic Fusion Energy (MFE) Nuclear Data Needs Activities, and invited specialists.

  20. Basic Science Living Skills for Today's World. Teacher's Edition.

    ERIC Educational Resources Information Center

    Zellers (Robert W.) Educational Services, Johnstown, PA.

    This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…

  1. Teaching basic science to optimize transfer.

    PubMed

    Norman, Geoff

    2009-09-01

    Basic science teachers share the concern that much of what they teach is soon forgotten. Although some evidence suggests that relatively little basic science is forgotten, it may not appear so, as students commonly have difficulty using these concepts to solve or explain clinical problems: This phenomenon, using a concept learned in one context to solve a problem in a different context, is known to cognitive psychologists as transfer. The psychology literature shows that transfer is difficult; typically, even though students may know a concept, fewer than 30% will be able to use it to solve new problems. However a number of strategies to improve transfer can be adopted at the time of initial teaching of the concept, in the use of exemplars to illustrate the concept, and in practice with additional problems. In this article, we review the literature in psychology to identify practical strategies to improve transfer. Critical review of psychology literature to identify factors that enhance or impede transfer. There are a number of strategies available to teachers to facilitate transfer. These include active problem-solving at the time of initial learning, imbedding the concept in a problem context, using everyday analogies, and critically, practice with multiple dissimilar problems. Further, mixed practice, where problems illustrating different concepts are mixed together, and distributed practice, spread out over time, can result in significant and large gains. Transfer is difficult, but specific teaching strategies can enhance this skill by factors of two or three.

  2. [Evolutionary medicine: an emergent basic science].

    PubMed

    Spotorno, Angel E

    2005-02-01

    Evolutionary Medicine is an emergent basic science that offers new and varied perspectives to the comprehension of human health. The application of classic evolutionary theories (descent with modification, and natural selection) to the human organism, to its pathogens, and their mutual co-evolution, provides new explanations about why we get sick, how we can prevent this, and how we can heal. Medicine has focused mainly on the proximate or immediate causes of diseases and the treatment of symptoms, and very little on its evolutionary or mediate causes. For instance, the present human genome and phenotypes are essentially paleolithic ones: they are not adapted to modern life style, thus favoring the so-called diseases of civilization (ie: ateroesclerosis, senescence, myopia, phobias, panic attacks, stress, reproductive cancers). With the evolutionary approach, post-modern medicine is detecting better the vulnerabilities, restrictions, biases, adaptations and maladaptations of human body, its actual diseases, and its preventions.

  3. Endothelial glycocalyx: basic science and clinical implications.

    PubMed

    Pillinger, N L; Kam, Pca

    2017-05-01

    The classic Starling principle proposed that microvascular fluid exchange was determined by a balance of hydrostatic and oncotic pressures relative to the vascular wall and this movement of water was regulated by gaps in the intercellular spaces. However, current literature on the endothelial glycocalyx (a jelly-like protective layer covering the luminal surface of the endothelium) has revised Starling's traditional concepts. This article aims to summarise the literature on the glycocalyx related to its basic science, clinical settings inciting injury, protective strategies and clinical perspectives. Perioperative damage to the glycocalyx structure can increase vascular permeability leading to interstitial fluid shifts, oedema, and increased surgical morbidity. Pathological shedding of the glycocalyx occurs in response to mechanical cellular stress, endotoxins, inflammatory mediators, atrial natriuretic peptide, ischaemia-reperfusion injury, free oxygen radicals and hyperglycaemia. Increased understanding of the endothelial glycocalyx may change perioperative fluid management, and therapeutic strategies aimed at its preservation may improve patient outcomes.

  4. Basic Science of Muscle Neurotization: A Review.

    PubMed

    Konofaos, Petros; Wallace, Robert D

    2015-09-01

    Traumatic nerve injuries continue to be considered a challenge in the field of nerve microsurgical reconstruction. Despite the advances in microsurgical repair techniques, motor function recovery is not adequate in severe nerve injuries, especially when there is separation of the motor nerve from the muscle tissue. The technique of reinnervating skeletal muscles by insertion within it of a donor nerve was developed at the beginning of the 20th century during World War I, when injuries and poliomyelitis produced paralytics for whom no therapy was available. Only a few reports of clinically successful reinnervation exist, and clinical application of the method during the following decades has been limited. However, the functional value of this procedure remains a matter of controversy. The purpose of this review is to present what is known in basic science about direct neurotization of muscle along with a brief historical review. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  5. Atomic Energy Basics, Understanding the Atom Series.

    ERIC Educational Resources Information Center

    Atomic Energy Commission, Oak Ridge, TN. Div. of Technical Information.

    This booklet is part of the "Understanding the Atom Series," though it is a later edition and not included in the original set of 51 booklets. A basic survey of the principles of nuclear energy and most important applications are provided. These major topics are examined: matter has molecules and atoms, the atom has electrons, the nucleus,…

  6. Developing Basic Space Science World-Wide

    NASA Astrophysics Data System (ADS)

    Wamsteker, W.; Albrecht, Rudolf; Haubold, Hans J.

    2004-03-01

    When the first United Nations/European Space Agency Workshop for Basic Space Science was planned to be held in Bangalore, India (1991) on the invitation of ISRO, few of those involved could expect that a unique forum was going to be created for scientific dialogue between scientists from developing and industrialized nations. As the format of the first workshop was on purpose left free with time for presentations, working sessions, and plenary discussions, the workshop was left to find its own dynamics. After a decade of UN/ESA Workshops, this book brings together the historical activities, the plans which have been developed over the past decade in the different nations, and the results which have materialized during this time in different developing nations. It aims to achieve for development agencies to be assisted in ways to find more effective tools for the application of development aid. The last section of the book contains a guide for teachers to introduce astrophysics into university physics courses. This will be of use to teachers in many nations. Everything described in this book is the result of a truly collective effort from all involved in all UN/ESA workshops. The mutual support from the participants has helped significantly to implement some of the accomplishments described in the book. Rather than organizing this book in a subject driven way, it is essentially organized according to the common economic regions of the world, as defined by the United Nations (Africa, Asia and the Pacific, Europe, Latin America and the Caribbean, Western Asia). This allows better recognition of the importance of a regional (and at times) global approach to basic space science for the developing nation's world wide. It highlights very specific scientific investigations which have been completed successfully in the various developing nations. The book supplements the published ten volumes of workshop proceedings containing scientific papers presented in the workshops

  7. The use of simulation in teaching the basic sciences.

    PubMed

    Eason, Martin P

    2013-12-01

    To assess the current use of simulation in medical education, specifically, the teaching of the basic sciences to accomplish the goal of improved integration. Simulation is increasingly being used by the institutions to teach the basic sciences. Preliminary data suggest that it is an effective tool with increased retention and learner satisfaction. Medical education is undergoing tremendous change. One of the directions of that change is increasing integration of the basic and clinical sciences to improve the efficiency and quality of medical education, and ultimately to improve the patient care. Integration is thought to improve the understanding of basic science conceptual knowledge and to better prepare the learners for clinical practice. Simulation because of its unique effects on learning is currently being successfully used by many institutions as a means to produce that integration through its use in the teaching of the basic sciences. Preliminary data indicate that simulation is an effective tool for basic science education and garners high learner satisfaction.

  8. Exploring the basic science of prolapse meshes

    PubMed Central

    Liang, Rui; Knight, Katrina; Abramowitch, Steve; Moalli, Pamela A.

    2016-01-01

    Purpose of review Polypropylene mesh has been widely used in the surgical repair of pelvic organ prolapse. However, low but persistent rates of complications related to mesh, most commonly mesh exposure and pain, have hampered its use. Complications are higher following transvaginal implantation prompting the Food and Drug Administration to release two public health notifications warning of complications associated with transvaginal mesh use (PHN 2008 and 2011) and to upclassify transvaginal prolapse meshes from Class II to Class III devices. Although there have been numerous studies to determine the incidence and management of mesh complications as well as impact on quality of life, few studies have focused on mechanisms. Recent findings In this review, we summarize the current understanding of how mesh textile properties and mechanical behavior impact vaginal structure and function, as well as the local immune response. We also discuss how mesh properties change in response to loading. Summary We highlight a few areas of current and future research to emphasize collaborative strategies that incorporate basic science research to improve patient outcomes. PMID:27517341

  9. Exploring the basic science of prolapse meshes.

    PubMed

    Liang, Rui; Knight, Katrina; Abramowitch, Steve; Moalli, Pamela A

    2016-10-01

    Polypropylene mesh has been widely used in the surgical repair of pelvic organ prolapse. However, low but persistent rates of complications related to mesh, most commonly mesh exposure and pain, have hampered its use. Complications are higher following transvaginal implantation prompting the Food and Drug Administration to release two public health notifications warning of complications associated with transvaginal mesh use (PHN 2008 and 2011) and to upclassify transvaginal prolapse meshes from Class II to Class III devices. Although there have been numerous studies to determine the incidence and management of mesh complications as well as impact on quality of life, few studies have focused on mechanisms. In this review, we summarize the current understanding of how mesh textile properties and mechanical behavior impact vaginal structure and function, as well as the local immune response. We also discuss how mesh properties change in response to loading. We highlight a few areas of current and future research to emphasize collaborative strategies that incorporate basic science research to improve patient outcomes.

  10. Basic Solar Energy Research in Japan (2011 EFRC Forum)

    ScienceCinema

    Domen, Kazunari (University of Tokyo)

    2016-07-12

    Kazunari Domen, Chemical System Engineering Professor at the University of Tokyo, was the second speaker in the May 26, 2011 EFRC Forum session, "Global Perspectives on Frontiers in Energy Research." In his presentation, Professor Domen talked about basic solar energy research in Japan. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss "Science for our Nation's Energy Future." In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several “grand challenges” and use-inspired “basic research needs” recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  11. Future Energy Technology. A Basic Teaching Unit on Energy. Revised.

    ERIC Educational Resources Information Center

    McDermott, Hugh, Ed.; Scharmann, Larry, Ed.

    Recommended for grades 7-12 language arts, science, and social studies classes, this 5-7 day unit encourages students to investigate alternative energy sources through research. Focusing on geothermal energy, tide and ocean, fusion, wind, biomass, and solar energy as possible areas of consideration, the unit attempts to create an awareness of the…

  12. Future Energy Technology. A Basic Teaching Unit on Energy. Revised.

    ERIC Educational Resources Information Center

    McDermott, Hugh, Ed.; Scharmann, Larry, Ed.

    Recommended for grades 7-12 language arts, science, and social studies classes, this 5-7 day unit encourages students to investigate alternative energy sources through research. Focusing on geothermal energy, tide and ocean, fusion, wind, biomass, and solar energy as possible areas of consideration, the unit attempts to create an awareness of the…

  13. Science-based neurorehabilitation: recommendations for neurorehabilitation from basic science.

    PubMed

    Nielsen, Jens Bo; Willerslev-Olsen, Maria; Christiansen, Lasse; Lundbye-Jensen, Jesper; Lorentzen, Jakob

    2015-01-01

    Neuroscience has fundamentally changed the understanding of learning and memory within recent years. Here, the authors discuss a number of specific areas where they believe new understanding of the CNS from basic science is having a fundamental impact on neurorehabilitation and is leading to new therapeutic approaches. These areas have constituted a basis for development of some basic principles for neurorehabilitation: Optimal rehabilitation should involve (a) active (patient) participation in the training, (b) training that does not only involve many repetitions, but also continues to challenge the skill of the training person, (c) motivation and reward, (d) intensive training and practice over a long time, (e) careful organization of the training in relation to other activities, and (f) incorporation of other potentially beneficial parameters such as sleep and diet. It should in this relation also be pointed out that albeit neurorehabilitation may be predicted to have the most optimal effect early in life and as soon after injury as possible, there is no reason to believe that beneficial effects of training may not be obtained late in life or several years after injury.

  14. Attendance at Basic Sciences Lectures: A Student Perspective.

    ERIC Educational Resources Information Center

    Mendez, Antonio; Ramos, Gilberto

    Factors that may affect a medical student's decision to attend basic science lectures were investigated. Basic science faculty members and administrators' views on student lecture attendance were elicited to construct a questionnaire. A total of 103 first-year and 75 second-year medical students attending a Puerto Rican medical school responded to…

  15. Clinical Competencies and the Basic Sciences: An Online Case Tutorial Paradigm for Delivery of Integrated Clinical and Basic Science Content

    ERIC Educational Resources Information Center

    DiLullo, Camille; Morris, Harry J.; Kriebel, Richard M.

    2009-01-01

    Understanding the relevance of basic science knowledge in the determination of patient assessment, diagnosis, and treatment is critical to good medical practice. One method often used to direct students in the fundamental process of integrating basic science and clinical information is problem-based learning (PBL). The faculty facilitated small…

  16. Populations. Basic Edition. Science for Micronesia.

    ERIC Educational Resources Information Center

    Trust Territory of the Pacific Islands Dept. of Education, Saipan.

    This teacher's guide is for an elementary school science unit designed for use with third grade (or older) children in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of…

  17. Researchers warn of neglect to basic science

    NASA Astrophysics Data System (ADS)

    Banks, Michael

    2010-03-01

    Russia is losing its standing as a scientific powerhouse and its science is in a state of decline, according to a new report by the information-services provider Thomson Reuters. Entitled "The New Geography of Science: Research and Collaboration in Russia", the report warns that the country's research base "has a problem, and it shows little sign of a solution".

  18. TEACHING PHYSICS: Visual Basic science simulations

    NASA Astrophysics Data System (ADS)

    Evans, J. G.

    2000-01-01

    We are exploring the use of science simulation/modelling programs for teaching a variety of science concepts across the age range. The programs have been converted from the original RMBasic thanks to technological advances in equipment. We find that the programs complement practical work and allow in-depth analysis using multi-tasking with other programs.

  19. Basic Sciences Fertilizing Clinical Microbiology and Infection Management.

    PubMed

    Baquero, Fernando

    2017-08-15

    Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of "practice deconstruction" might reveal basic questions, as in de-differentiation of tissue cells. Basic sciences, microbiology, infectious diseases, and public health constitute an epistemological gradient that should also be an investigational continuum. The coexistence of all these interests and their cross-fertilization should be favored by interdisciplinary, integrative research organizations working simultaneously in the analytical and synthetic dimensions of scientific knowledge. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

  20. Energy, information science, and systems science

    SciTech Connect

    Wallace, Terry C; Mercer - Smith, Janet A

    2011-02-01

    This presentation will discuss global trends in population, energy consumption, temperature changes, carbon dioxide emissions, and energy security programs at Los Alamos National Laboratory. LANL's capabilities support vital national security missions and plans for the future. LANL science supports the energy security focus areas of impacts of Energy Demand Growth, Sustainable Nuclear Energy, and Concepts and Materials for Clean Energy. The innovation pipeline at LANL spans discovery research through technology maturation and deployment. The Lab's climate science capabilities address major issues. Examples of modeling and simulation for the Coupled Ocean and Sea Ice Model (COSIM) and interactions of turbine wind blades and turbulence will be given.

  1. The relevance of basic sciences in undergraduate medical education.

    PubMed

    Lynch, C; Grant, T; McLoughlin, P; Last, J

    2016-02-01

    Evolving and changing undergraduate medical curricula raise concerns that there will no longer be a place for basic sciences. National and international trends show that 5-year programmes with a pre-requisite for school chemistry are growing more prevalent. National reports in Ireland show a decline in the availability of school chemistry and physics. This observational cohort study considers if the basic sciences of physics, chemistry and biology should be a prerequisite to entering medical school, be part of the core medical curriculum or if they have a place in the practice of medicine. Comparisons of means, correlation and linear regression analysis assessed the degree of association between predictors (school and university basic sciences) and outcomes (year and degree GPA) for entrants to a 6-year Irish medical programme between 2006 and 2009 (n = 352). We found no statistically significant difference in medical programme performance between students with/without prior basic science knowledge. The Irish school exit exam and its components were mainly weak predictors of performance (-0.043 ≥ r ≤ 0.396). Success in year one of medicine, which includes a basic science curriculum, was indicative of later success (0.194 ≥ r (2) ≤ 0.534). University basic sciences were found to be more predictive than school sciences in undergraduate medical performance in our institution. The increasing emphasis of basic sciences in medical practice and the declining availability of school sciences should mandate medical schools in Ireland to consider how removing basic sciences from the curriculum might impact on future applicants.

  2. BASIC STEPS IN DESIGNING SCIENCE LABORATORIES.

    ERIC Educational Resources Information Center

    WHITNEY, FRANK L.

    PLANNERS OF CURRENT UNIVERSITY LABORATORIES OFTEN MAKE THE SAME MISTAKES MADE BY INDUSTRIAL LABORATORIES 20 YEARS AGO. THIS CAN BE REMEDIED BY INCREASED COMMUNICATION BETWEEN SCIENTISTS AND DESIGNERS IN SEMINARS DEFINING THE BASIC NEEDS OF A PARTICULAR LABORATORY SITUATION. ELECTRONIC AND MECHANICAL EQUIPMENT ACCOUNT FOR OVER 50 PER CENT OF TOTAL…

  3. BASIC STEPS IN DESIGNING SCIENCE LABORATORIES.

    ERIC Educational Resources Information Center

    WHITNEY, FRANK L.

    PLANNERS OF CURRENT UNIVERSITY LABORATORIES OFTEN MAKE THE SAME MISTAKES MADE BY INDUSTRIAL LABORATORIES 20 YEARS AGO. THIS CAN BE REMEDIED BY INCREASED COMMUNICATION BETWEEN SCIENTISTS AND DESIGNERS IN SEMINARS DEFINING THE BASIC NEEDS OF A PARTICULAR LABORATORY SITUATION. ELECTRONIC AND MECHANICAL EQUIPMENT ACCOUNT FOR OVER 50 PER CENT OF TOTAL…

  4. [Basic areas of medical science in Uzbekistan].

    PubMed

    Abdullakhodzhaeva, M S

    2016-01-01

    The paper considers the issues of medicine development in the Republic of Uzbekistan and the contribution made by prominent scientists developing effective methods for diagnosing and treating different diseases in medical science. A great part is assigned to medical science advances in our country. To solve the urgent problems of public health, much attention is given to the training of scientific manpower, the setting up of specialized research and practical medical centers of different profile, research laboratories of medical higher educational establishments as a base for conducting researches and investigations, which will be able to improve the quality of medical care to the population and corresponds to a health care reform program.

  5. Learning basic science alongside veterinary students: creating an interactive classroom.

    PubMed

    Brown, Scott A

    2004-01-01

    Dr. Scott Brown's dedication and contribution to the instructional programs of the University of Georgia College of Veterinary Medicine have been exceptionally meritorious. In the last eight years, he has served with the leadership among faculty in the design and approval of a new curriculum, and as chair of the curriculum committee he led the College in its implementation. Throughout this period his research productivity, mentorship of professional and graduate students, and professional development continued. Dr. Brown instills energy, broadens learning experiences from personal and professional development to basic science, and, in all probability, provides positive, life-changing experiences for his students. I am very pleased that he was recognized in 2003 with the Carl J. Norden National Distinguished Teacher Award.

  6. Teaching Basic Probability in Undergraduate Statistics or Management Science Courses

    ERIC Educational Resources Information Center

    Naidu, Jaideep T.; Sanford, John F.

    2017-01-01

    Standard textbooks in core Statistics and Management Science classes present various examples to introduce basic probability concepts to undergraduate business students. These include tossing of a coin, throwing a die, and examples of that nature. While these are good examples to introduce basic probability, we use improvised versions of Russian…

  7. Parsesciencing: A Basic Science Mode of Inquiry.

    PubMed

    Parse, Rosemarie Rizzo

    2016-10-01

    The purpose of this article is to introduce the language for the mode of inquiry, now known as Parsesciencing. The language for the Humanbecoming Hermeneutic Sciencing was introduced in an earlier volume of Nursing Science Quarterly. Language both reflects and cocreates meaning. The language of sciencing is everchanging; it is an evolutionary emergent, shifting as new ideas cocreate horizons beyond. The language set forth here is to articulate more explicitly meanings of the modes of inquiry consistent with the humanbecoming paradigm and distinct from modes of inquiry in other disciplines. In dwelling with the findings of published and unpublished studies that were guided by humanbecoming, new insights arose, and with creative conceptualizing these new insights gave birth to new meanings, thus different language. The language introduced here includes the following: Parsesciencing as coming to know the meanings of universal humanuniverse living experiences, horizon of inquiry, foreknowings, inquiry stance, mode of inquiry, historians, dialoging-engaging, scholar, distilling-fusing, discerning extant moment, transmogrifying, transsubstantiating, and newknowings. Note: an example of the new language with a Parsesciencing inquiry on the universal humanuniverse living experience of feeling unsure by Sandra Bunkers appears later in this issue.

  8. Science Serving the Nation: The Impact of Basic Research

    SciTech Connect

    None, None

    2012-01-01

    Impacts: The BES program supports basic research that underpins a broad range of energy technologies. Research in materials sciences and engineering leads to the development of materials that improve the efficiency, economy, environmental acceptability, and safety of energy generation, conversion, transmission, storage, and use. For example, advances in superconductivity have been introduced commercially in a number of demonstration projects around the country. Improvements in alloy design for high temperature applications are used in commercial furnaces and in green technologies such as lead-free solder. Research in chemistry has led to advances such as efficient combustion systems with reduced emissions of pollutants; new solar photoconversion processes; improved catalysts for the production of fuels and chemicals; and better separations and analytical methods for applications in energy processes, environmental remediation, and waste management. Research in geosciences results in advanced monitoring and measurement techniques for reservoir definition and an understanding of the fluid dynamics of complex fluids through porous and fractured subsurface rock. Research in the molecular and biochemical nature of photosynthesis aids the development of solar photo-energy conversion. The BES program also plays a major role in enabling the nanoscale revolution. The importance of nanoscience to future energy technologies is clearly reflected by the fact that all of the elementary steps of energy conversion (e.g., charge transfer, molecular rearrangement, and chemical reactions) take place on the nanoscale. The development of new nanoscale materials, as well as the methods to characterize, manipulate, and assemble them, create an entirely new paradigm for developing new and revolutionary energy technologies.

  9. The Museum of Science and Industry Basic List of Children's Science Books, 1986.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    This first supplement to the Museum of Science and Industry Basic List of Children's Science Books contains books received for the museum's 13th annual children's science book fair. Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; environment/conservation;…

  10. The Museum of Science and Industry Basic List of Children's Science Books, 1986.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    This first supplement to the Museum of Science and Industry Basic List of Children's Science Books contains books received for the museum's 13th annual children's science book fair. Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; environment/conservation;…

  11. Family Science Activities for Adult Basic and Literacy Education.

    ERIC Educational Resources Information Center

    Community Action Southwest, Waynesburg, PA.

    A staff development project created a series of family science activities to be used in adult basic and literacy education (ABLE) and family literacy programs and a training guide for staff and volunteers. The training guide provides background principles and concepts for science activities. The activities identify materials and indicate ways the…

  12. The Basic Mathematics of Astronomy: A Sourcebook for Science Teachers.

    ERIC Educational Resources Information Center

    Therkelsen, Edward Robert

    An attempt was made in this study to determine if there was a need for a sourcebook of the basic mathematics of astronomy for secondary school science teachers. Science teachers involved and interested in the teaching of astronomy were located through letters to the superintendents of the 400 largest school districts in the United States. Names…

  13. Review of basic science advances in HIV.

    PubMed

    Stevenson, Mario

    2012-01-01

    The Conference on Retroviruses and Opportunistic Infections (CROI) is held annually to provide a forum for scientists to hear the most recent advances in the field of HIV and AIDS research. Although the conference has a primary mission to showcase advances in the prevention and management of HIV-1 infection and opportunistic infections (in particular, tuberculosis and hepatitis C virus [HCV]), there continues to be a strong basic research component. Research on cellular factors that influence the interplay between the virus and the host cell, and especially, cellular factors that antagonize viral replication, had the greatest presence at the conference. In the area of retroviral pathogenesis, research on viral reservoirs and mechanisms of viral persistence in the face of antiretroviral therapy generated considerable interest. Research on mechanisms of viral persistence is beginning to reveal strategies, some of which were the focus of presentations at CROI, to eliminate long-lived viral reservoirs.

  14. Welding As Science: Applying Basic Engineering Principles to the Discipline

    NASA Technical Reports Server (NTRS)

    Nunes, A. C., Jr.

    2010-01-01

    This Technical Memorandum provides sample problems illustrating ways in which basic engineering science has been applied to the discipline of welding. Perhaps inferences may be drawn regarding optimal approaches to particular welding problems, as well as for the optimal education for welding engineers. Perhaps also some readers may be attracted to the science(s) of welding and may make worthwhile contributions to the discipline.

  15. Fluorescein angiography basic science and engineering.

    PubMed

    Wolfe, D R

    1986-12-01

    Fluorescein angiography is an application of the physical phenomenon of fluorescence, which is phosphorescence in which the quantum mechanical decay curve is so rapid that it appears instantaneous, and it consequently has no afterglow. Sodium fluorescein is excited by light energy between 465 and 490 nm, and it decays into a lower state emitting light energy between 520 and 530 nm as fluorescent radiation. The free electrons available for excitation are reduced by chemical bonding between the fluorescein dye and plasma proteins to which up to 80% of the dye is bound in the bloodstream, thus reducing overall fluorescence. Optimalization of the observed and recorded fluorescence is afforded by providing exciter and barrier filters with as little overlap as possible to reduce or eliminate contrast reducing pseudofluorescence.

  16. Science Activities in Energy: Solar Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 12 activities relating to solar energy. Activities are simple, concrete experiments for fourth, fifth, and sixth grades, which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's supplement…

  17. Science Activities in Energy: Solar Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 12 activities relating to solar energy. Activities are simple, concrete experiments for fourth, fifth, and sixth grades, which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's supplement…

  18. Science Activities in Energy: Chemical Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 15 activities relating to chemical energy. Activities are simple, concrete experiments for fourth, fifth and sixth grades which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's…

  19. Science Activities in Energy: Electrical Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 16 activities relating to electrical energy. Activities are simple, concrete experiments for fourth, fifth and sixth grades which illustrate principles and problems relating to energy. Each activity is outlined in a single card which is introduced by a question. A teacher's…

  20. Science Activities in Energy: Chemical Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 15 activities relating to chemical energy. Activities are simple, concrete experiments for fourth, fifth and sixth grades which illustrate principles and problems relating to energy. Each activity is outlined on a single card which is introduced by a question. A teacher's…

  1. The Museum of Science and Industry Basic List of Children's Science Books, 1987.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    Presented is the second annual supplement to the Museum of Science and Industry Basic List of Children's Science Books 1973-1984. In this supplement, children's science books are listed under the headings of animals, astronomy, aviation and space, biography, earth sciences, encyclopedias and reference books, environment and conservation, fiction,…

  2. The Museum of Science and Industry Basic List of Children's Science Books, 1987.

    ERIC Educational Resources Information Center

    Richter, Bernice, Comp.; Wenzel, Duane, Comp.

    Presented is the second annual supplement to the Museum of Science and Industry Basic List of Children's Science Books 1973-1984. In this supplement, children's science books are listed under the headings of animals, astronomy, aviation and space, biography, earth sciences, encyclopedias and reference books, environment and conservation, fiction,…

  3. Research Opportunities at the Basic Plasma Science Facility

    NASA Astrophysics Data System (ADS)

    Gekelman, Walter

    2005-04-01

    The Basic Plasma Science Facility (BAPSF) at (UCLA) is a user facility sponsored by the Department of Energy and the National Science Foundation. The purpose is to provide access, free of charge, to qualified national and international scientists to a state-of-the art, large plasma device (LAPD) which, permits the exploration of frontier topics in plasma science under controlled conditions. Some of the research activities are related to space plasma investigations, others explore fundamental issues of interest to fusion research. The operation is centered on the LAPD device developed by the UCLA research team. The machine produces quiescent and reproducible plasma discharges having typical duration of 10 msec (trep = 1 Hz), accessible throughout the day. The plasma column is 18 meters in length and 60 cm in diameter. The magnetic field can be varied continuously up to 2.5 kG. Fully ionized discharges in He, Ar, and Ne are available. Representative parameters are: The machine has 360 access ports. Qualified users have access to all of the machine diagnostics. Each user group is assigned a staff scientist who runs the machine and provides the necessary technical expertise to implement their research project. To obtain access a prospective user contacts the director and then submits a white paper. Instructions for this can be found at http://plasma.physics.ucla.edu/bapsf. The white paper is reviewed by an external committee. There are currently 11 active projects. This talk will give details of the device and briefly describe some of the experiments in progress.

  4. Speaking of food: connecting basic and applied plant science.

    PubMed

    Gross, Briana L; Kellogg, Elizabeth A; Miller, Allison J

    2014-10-01

    The Food and Agriculture Organization (FAO) predicts that food production must rise 70% over the next 40 years to meet the demands of a growing population that is expected to reach nine billion by the year 2050. Many facets of basic plant science promoted by the Botanical Society of America are important for agriculture; however, more explicit connections are needed to bridge the gap between basic and applied plant research. This special issue, Speaking of Food: Connecting Basic and Applied Plant Science, was conceived to showcase productive overlaps of basic and applied research to address the challenges posed by feeding billions of people and to stimulate more research, fresh connections, and new paradigms. Contributions to this special issue thus illustrate some interactive areas of study in plant science-historical and modern plant-human interaction, crop and weed origins and evolution, and the effects of natural and artificial selection on crops and their wild relatives. These papers provide examples of how research integrating the basic and applied aspects of plant science benefits the pursuit of knowledge and the translation of that knowledge into actions toward sustainable production of crops and conservation of diversity in a changing climate. © 2014 Botanical Society of America, Inc.

  5. XVII International AIDS Conference: From Evidence to Action - Basic science

    PubMed Central

    2009-01-01

    This article focuses on the sessions in which basic science research was presented at the XVII International AIDS Conference (AIDS 2008). It also provides an analysis of basic science issues which generated significant discussion and debate at the conference and are likely to have implications for future laboratory and clinical research. Data presented at AIDS 2008 confirmed the speed with which HIV establishes latent viral reservoirs following infection and the resulting challenges to viral eradication given how effectively HIV proviral RNA inserts itself into human DNA within these reservoirs. Studies also raised questions about the source of residual viremia and how these might be targeted by novel therapeutic approaches. PMID:19811669

  6. Contributions of Basic Sciences to Science of Education. Studies in Educational Administration.

    ERIC Educational Resources Information Center

    Lall, Bernard M.

    The science of education has been influenced by the basic sciences to the extent that educational research now has been able to modernize its approach by accepting and using the basic scientific methodology and experimental techniques. Using primarily the same steps of scientific investigations, education today holds a place of much greater esteem…

  7. Science Activities in Energy: Wind Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Included in this science activities energy package are 12 activities related to wind energy for elementary students. Each activity is outlined on a single card and is introduced by a question. Topics include: (1) At what time of day is there enough wind to make electricity where you live?; (2) Where is the windiest spot on your schoolground?; and…

  8. Science Activities in Energy: Wind Energy.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Included in this science activities energy package are 12 activities related to wind energy for elementary students. Each activity is outlined on a single card and is introduced by a question. Topics include: (1) At what time of day is there enough wind to make electricity where you live?; (2) Where is the windiest spot on your schoolground?; and…

  9. Science Activities in Energy: Conservation.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Presented is a science activities in energy package which includes 14 activities relating to energy conservation. Activities are simple, concrete experiments for fourth, fifth and sixth grades, which illustrate principles and problems relating to energy. Each activity is outlined on a simple card which is introduced by a question. A teacher's…

  10. Basic Energy Sciences 2011 Summary Report

    SciTech Connect

    2011-01-01

    This report describes how BES is organized and operates to accomplish our mission and presents selected accomplishments to illustrate some exciting new scientific advances that resulted from BES-supported research. Also included are references to supplementary resources that provide additional information about BES strategic planning, research, and user facilities.

  11. Basic Energy Sciences 2014 Summary Report

    SciTech Connect

    2014-02-01

    This report describes how BES is organized and operates to accomplish our mission and presents selected accomplishments to illustrate some exciting new scientific advances that resulted from BES-supported research. Also included are references to supplementary resources that provide additional information about BES strategic planning, research, and user facilities.

  12. Nutrition in pediatrics: basic science and clinical applications

    USDA-ARS?s Scientific Manuscript database

    The first edition of Nutrition in Pediatrics: Basic Science and Clinical Applications was published in 1985 to "...offer a comprehensive review of general concepts of nutrition as they pertain to pediatrics as well as relevant information on the nutritional management of specific disease states." A ...

  13. One Man's Approach to a Basic Course in Geological Sciences.

    ERIC Educational Resources Information Center

    Gould, Stephen Jay

    1984-01-01

    Presents a twofold approach to teaching basic geology based on five principles to make science accessible to students who think they are bored with or afraid of the subject. The approach focuses on: appealing to the mind (to attack boredom) and appealing to the emotions (to attack fear). (BC)

  14. Pima College Students' Knowledge of Selected Basic Physical Science Concepts.

    ERIC Educational Resources Information Center

    Iadevaia, David G.

    In 1989 a study was conducted at Pima Community College (PCC) to assess students' knowledge of basic physical science concepts. A three-part survey instrument was administered to students in a second semester sociology class, a first semester astronomy class, a second semester Spanish class, and a first semester physics class. The survey…

  15. A brief simulation intervention increasing basic science and clinical knowledge.

    PubMed

    Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l=515) and the intervention group received lecture plus a simulation exercise (n l+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.

  16. Curriculum Considerations for Correlating Basic and Clinical Sciences.

    ERIC Educational Resources Information Center

    Mackenzie, Richard S.

    1980-01-01

    Six ways a dentist can profit from the basic sciences are: (1) increased sensitivity to the environment, (2) improved judgment, (3) better explanations to patients, (4) enhanced ability to learn, (5) improved communication with health professionals, and (6) greater role diversity. Literature is reviewed related to mental processes. (Author/MLW)

  17. One Man's Approach to a Basic Course in Geological Sciences.

    ERIC Educational Resources Information Center

    Gould, Stephen Jay

    1984-01-01

    Presents a twofold approach to teaching basic geology based on five principles to make science accessible to students who think they are bored with or afraid of the subject. The approach focuses on: appealing to the mind (to attack boredom) and appealing to the emotions (to attack fear). (BC)

  18. A Case Study of a Nontraditional Basic Science Curriculum.

    ERIC Educational Resources Information Center

    Roth, Gerald I.; And Others

    1982-01-01

    A critical analysis of a university dental school's 10-year experience with a self-instructional basic sciences curriculum is presented, focusing on development of the curriculum, positive and negative effects on students and faculty, materials and format used, costs, and other administrative considerations. (Author/MSE)

  19. BASIC ELECTRICITY. SCIENCE IN ACTION SERIES, NUMBER 14.

    ERIC Educational Resources Information Center

    CASSEL, RICHARD

    THIS TEACHING GUIDE, INVOLVING ACTIVITIES FOR DEVELOPING AN UNDERSTANDING OF BASIC ELECTRICITY, EMPHASIZES STUDENT INVESTIGATIONS RATHER THAN FACTS, AND IS BASED ON THE PREMISE THAT THE MAJOR GOAL IN SCIENCE TEACHING IS THE DEVELOPMENT OF THE INVESTIGATIVE ATTITUDE IN THE STUDENT. ACTIVITIES SUGGESTED INVOLVE SIMPLE DEMONSTRATIONS AND EXPERIMENTS…

  20. A brief simulation intervention increasing basic science and clinical knowledge.

    PubMed

    Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    Background The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. Purpose To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. Methods This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l=515) and the intervention group received lecture plus a simulation exercise (n l+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Results Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Discussion Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.

  1. A brief simulation intervention increasing basic science and clinical knowledge

    PubMed Central

    Sheakley, Maria L.; Gilbert, Gregory E.; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    Background The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. Purpose To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. Methods This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (nl=515) and the intervention group received lecture plus a simulation exercise (nl+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Results Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Discussion Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum. PMID:27060102

  2. The New Millennium and an Education That Captures the Basic Spirit of Science.

    ERIC Educational Resources Information Center

    Bybee, Rodger W.

    This document discusses reflections of the old and new millennium on education that capture the basic spirit of science. The explanation includes basic scientific ideas in physical sciences, earth systems, solar system and space; living systems; basic scientific thinking; the basic distinction between science and technology; basic connections…

  3. Basic Research in Materials Science and Economic Sustainable Growth

    NASA Astrophysics Data System (ADS)

    Habermeier, H.-U.

    2000-09-01

    The necessity of public funding of basic research has been proclaimed by V. Bush 1945 in the `social contract for science' and this concept has been unanimously accepted as a vital prerequisite for the wealth of nations during the past 50 years. Recent developments gave rise to a paradigm shift away from the Bush's concept. In this paper this development is critically explored and the economical impact of research is discussed. Current evolution in knowledge generation and a change of the political boundary conditions require a new concept for an integrated research system. Examples taken from the semiconductor industry serve as an indicator of the enabling importance of materials science and condensed matter physics in the past. Basic research in materials science of functional ceramics generated new developments that are believed to have similar impact in the future. Already appearing and in the years ahead more emphasized nature of materials science as an multidisciplinary activity serves a model for the proposal of the vision of an integrated system of basic research and education. This is a prerequisite to master the challenges we are facind in the next century. A science based winning culture is the model for the future.

  4. Computational science for energy research

    NASA Astrophysics Data System (ADS)

    Abgrall, Rémi; Koren, Barry

    2017-09-01

    Computational science complements theory and experiments. It can deliver knowledge and understanding in application areas where the latter two can not. Computational science is particularly important for the simulation of various energy-related processes, ranging from classical energy processes as combustion and subsurface oil-reservoir flows to more modern processes as wind-farm aerodynamics, photovoltaics and - very challenging from a computational perspective - tokamak-plasma physics.

  5. Integration of basic sciences and clinical sciences in oral radiology education for dental students.

    PubMed

    Baghdady, Mariam T; Carnahan, Heather; Lam, Ernest W N; Woods, Nicole N

    2013-06-01

    Educational research suggests that cognitive processing in diagnostic radiology requires a solid foundation in the basic sciences and knowledge of the radiological changes associated with disease. Although it is generally assumed that dental students must acquire both sets of knowledge, little is known about the most effective way to teach them. Currently, the basic and clinical sciences are taught separately. This study was conducted to compare the diagnostic accuracy of students when taught basic sciences segregated or integrated with clinical features. Predoctoral dental students (n=51) were taught four confusable intrabony abnormalities using basic science descriptions integrated with the radiographic features or taught segregated from the radiographic features. The students were tested with diagnostic images, and memory tests were performed immediately after learning and one week later. On immediate and delayed testing, participants in the integrated basic science group outperformed those from the segregated group. A main effect of learning condition was found to be significant (p<0.05). The results of this study support the critical role of integrating biomedical knowledge in diagnostic radiology and shows that teaching basic sciences integrated with clinical features produces higher diagnostic accuracy in novices than teaching basic sciences segregated from clinical features.

  6. Storytelling in Earth sciences: The eight basic plots

    NASA Astrophysics Data System (ADS)

    Phillips, Jonathan

    2012-11-01

    Reporting results and promoting ideas in science in general, and Earth science in particular, is treated here as storytelling. Just as in literature and drama, storytelling in Earth science is characterized by a small number of basic plots. Though the list is not exhaustive, and acknowledging that multiple or hybrid plots and subplots are possible in a single piece, eight standard plots are identified, and examples provided: cause-and-effect, genesis, emergence, destruction, metamorphosis, convergence, divergence, and oscillation. The plots of Earth science stories are not those of literary traditions, nor those of persuasion or moral philosophy, and deserve separate consideration. Earth science plots do not conform those of storytelling more generally, implying that Earth scientists may have fundamentally different motivations than other storytellers, and that the basic plots of Earth Science derive from the characteristics and behaviors of Earth systems. In some cases preference or affinity to different plots results in fundamentally different interpretations and conclusions of the same evidence. In other situations exploration of additional plots could help resolve scientific controversies. Thus explicit acknowledgement of plots can yield direct scientific benefits. Consideration of plots and storytelling devices may also assist in the interpretation of published work, and can help scientists improve their own storytelling.

  7. Making evolutionary biology a basic science for medicine

    PubMed Central

    Nesse, Randolph M.; Bergstrom, Carl T.; Ellison, Peter T.; Flier, Jeffrey S.; Gluckman, Peter; Govindaraju, Diddahally R.; Niethammer, Dietrich; Omenn, Gilbert S.; Perlman, Robert L.; Schwartz, Mark D.; Thomas, Mark G.; Stearns, Stephen C.; Valle, David

    2010-01-01

    New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease. PMID:19918069

  8. Preparing medical students for future learning using basic science instruction.

    PubMed

    Mylopoulos, Maria; Woods, Nicole

    2014-07-01

    The construct of 'preparation for future learning' (PFL) is understood as the ability to learn new information from available resources, relate new learning to past experiences and demonstrate innovation and flexibility in problem solving. Preparation for future learning has been proposed as a key competence of adaptive expertise. There is a need for educators to ensure that opportunities are provided for students to develop PFL ability and that assessments accurately measure the development of this form of competence. The objective of this research was to compare the relative impacts of basic science instruction and clinically focused instruction on performance on a PFL assessment (PFLA). This study employed a 'double transfer' design. Fifty-one pre-clerkship students were randomly assigned to either basic science instruction or clinically focused instruction to learn four categories of disease. After completing an initial assessment on the learned material, all participants received clinically focused instruction for four novel diseases and completed a PFLA. The data from the initial assessment and the PFLA were submitted to independent-sample t-tests. Mean ± standard deviation [SD] scores on the diagnostic cases in the initial assessment were similar for participants in the basic science (0.65 ± 0.11) and clinical learning (0.62 ± 0.11) conditions. The difference was not significant (t[42] = 0.90, p = 0.37, d = 0.27). Analysis of the diagnostic cases on the PFLA revealed significantly higher mean ± SD scores for participants in the basic science learning condition (0.72 ± 0.14) compared with those in the clinical learning condition (0.63 ± 0.15) (t[42] = 2.02, p = 0.05, d = 0.62). Our results show that the inclusion of basic science instruction enhanced the learning of novel related content. We discuss this finding within the broader context of research on basic science instruction, development of adaptive expertise and assessment

  9. Science Activities in Energy: Solar Energy II.

    ERIC Educational Resources Information Center

    Oak Ridge Associated Universities, TN.

    Included in this science activities energy package are 14 activities related to solar energy for secondary students. Each activity is outlined on a single card and is introduced by a question such as: (1) how much solar heat comes from the sun? or (2) how many times do you have to run water through a flat-plate collector to get a 10 degree rise in…

  10. Skin pH: from basic science to basic skin care.

    PubMed

    Ali, Saba M; Yosipovitch, Gil

    2013-05-01

    The "acid mantle" is a topic not only of historical interest, but also of clinical significance and has recently been linked to vital stratum corneum function. Despite compelling basic science evidence placing skin pH as a key factor in barrier homeostasis, stratum corneum integrity, and antimicrobial defense, application of the acid mantle concept in clinical care is lacking. We review recent basic science investigations into skin pH, discuss skin disorders characterized by aberrant pH, and finally discuss practical application for preservation of the acid mantle. Recognizing factors that alter skin pH and selecting products that preserve the acid mantle is of prime importance in treating dermatologic patients.

  11. Enlivening basic-science learning with current journal articles.

    PubMed

    Beresford, W A

    1996-01-01

    Pre-clinical medical students are often unconvinced that the basic sciences are clinically valuable. Also, they are hesitant about formulating ideas on their own from non-textbook sources. First-year medical students taking histology or neurobiology were persuaded to consult articles from the current biomedical literature. I set brief short-answer and labeled-sketch questions well before the course theoretical examinations, where the answers counted toward the score. The answers could only be found by reading in articles made available in the laboratory. The articles were chosen to display basic-science knowledge in action in clinical contexts. The questions offer an additional curriculum that can be steered toward, for example, concerns of family practice, mechanisms of common diseases, and topics of fast-increasing clinical importance.

  12. Comparison of Basic Science Knowledge Between DO and MD Students.

    PubMed

    Davis, Glenn E; Gayer, Gregory G

    2017-02-01

    With the coming single accreditation system for graduate medical education, medical educators may wonder whether knowledge in basic sciences is equivalent for osteopathic and allopathic medical students. To examine whether medical students' basic science knowledge is the same among osteopathic and allopathic medical students. A dataset of the Touro University College of Osteopathic Medicine-CA student records from the classes of 2013, 2014, and 2015 and the national cohort of National Board of Medical Examiners Comprehensive Basic Science Examination (NBME-CBSE) parameters for MD students were used. Models of the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) Level 1 scores were fit using linear and logistic regression. The models included variables used in both osteopathic and allopathic medical professions to predict COMLEX-USA outcomes, such as Medical College Admission Test biology scores, preclinical grade point average, number of undergraduate science units, and scores on the NBME-CBSE. Regression statistics were studied to compare the effectiveness of models that included or excluded NBME-CBSE scores at predicting COMLEX-USA Level 1 scores. Variance inflation factor was used to investigate multicollinearity. Receiver operating characteristic curves were used to show the effectiveness of NBME-CBSE scores at predicting COMLEX-USA Level 1 pass/fail outcomes. A t test at 99% level was used to compare mean NBME-CBSE scores with the national cohort. A total of 390 student records were analyzed. Scores on the NBME-CBSE were found to be an effective predictor of COMLEX-USA Level 1 scores (P<.001). The pass/fail outcome on COMLEX-USA Level 1 was also well predicted by NBME-CBSE scores (P<.001). No significant difference was found in performance on the NBME-CBSE between osteopathic and allopathic medical students (P=.322). As an examination constructed to assess the basic science knowledge of allopathic medical students, the NBME-CBSE is

  13. Developing basic space science world wide: progress report

    NASA Astrophysics Data System (ADS)

    Haubold, Hans J.; Wamsteker, Willem

    2004-01-01

    The UN/ESA Workshops on Basic Space Science is a long-term effort for the development of astronomy and regional and international cooperation in this field on a world wide basis, particularly in developing nations. The first four workshops in this series (India 1991, Costa Rica and Colombia 1992, Nigeria 1993, and Egypt 1994) addressed the status of astronomy in Asia and the Pacific, Latin America and the Caribbean, Africa, and Western Asia, respectively. One major recommendation that emanated from the first four workshops was that small astronomical facilities should be established in developing nations for research and education programmes at the university level and that such facilities should be networked. Subsequently, material for teaching and observing programmes for small optical telescopes were developed or recommended and astronomical telescope facilities have been inaugurated at UN/ESA Workshops on Basic Space Science in Sri Lanka (1995), Honduras (1997), and Jordan (1999). UN/ESA Workshops on Basic Space Science in Germany (1996), France (2000), Mauritius (2001), and Argentina (2002) emphasized the particular importance of astrophysical data systems and the virtual observatory concept for the development of astronomy on a world wide basis. Since 1996, the workshops are contributing to the development of the World Space Observatory (WSO/UV) concept. Achievements of the series of workshops are briefly summarized in this report.

  14. Some basic research problems related to energy

    NASA Astrophysics Data System (ADS)

    The prediction and evaluation of thermophysical data of fluids and fluid mixtures are discussed. Models which calculate the transport properties of fluid mixtures according to their dependence on size and mass of the constituent particles are discussed. The application of nonlinear evolution equations to energy related processes is discussed. It is expected that the remarkable progress in this field will have significant practical uses.

  15. PROJECT SUCCESS: Marine Science. (Introductory Packet, Basic Marine Science Laboratory Techniques, Oceanographic Instruments, Individual Projects, Bibliography).

    ERIC Educational Resources Information Center

    Demaray, Bryan

    Five packets comprise the marine science component of an enrichment program for gifted elementary students. Considered in the introductory section are identification (pre/post measure) procedures. Remaining packets address the following topics (subtopics in parentheses): basic marine science laboratory techniques (microscope techniques and metric…

  16. PROJECT SUCCESS: Marine Science. (Introductory Packet, Basic Marine Science Laboratory Techniques, Oceanographic Instruments, Individual Projects, Bibliography).

    ERIC Educational Resources Information Center

    Demaray, Bryan

    Five packets comprise the marine science component of an enrichment program for gifted elementary students. Considered in the introductory section are identification (pre/post measure) procedures. Remaining packets address the following topics (subtopics in parentheses): basic marine science laboratory techniques (microscope techniques and metric…

  17. "Science Citation Index" Data as a Safety Net for Basic Science Books Considered for Weeding.

    ERIC Educational Resources Information Center

    Burdick, Amrita J.

    1989-01-01

    Describes the use of the "Science Citation Index" in deciding whether to keep older basic science books that have failed to meet other criteria for collection retention. It is concluded that manual searching of the indexes proved feasible and reliable, while the lack of book titles on the online version reduced reliability of weeding…

  18. Clinical competencies and the basic sciences: an online case tutorial paradigm for delivery of integrated clinical and basic science content.

    PubMed

    DiLullo, Camille; Morris, Harry J; Kriebel, Richard M

    2009-10-01

    Understanding the relevance of basic science knowledge in the determination of patient assessment, diagnosis, and treatment is critical to good medical practice. One method often used to direct students in the fundamental process of integrating basic science and clinical information is problem-based learning (PBL). The faculty facilitated small group discussion format traditionally used for PBL is a significant challenge for faculty and facilities with a large class. To provide inductive learning to a large class early in the preclerkship curriculum, a series of online, case-based tutorials was created using the method of inquiry-based learning. The tutorial paradigm is designed to challenge students through a guided inquiry process in which clinical skills and basic science information are seamlessly joined. The psychosocial dimension of patient care is added to the documented case presentation of the tutorials in the form of patient/physician history taking and physical examination videos. These videos augment the written case with additional information providing the student with visual exposure in methods of patient communication and appropriate professional patient/physician interactions that address competencies of patient care, communication, and professionalism. The tutorials were made available via learning management system course sites. The study tracked usage of the tutorials by 270 first-year medical students.

  19. Tendon basic science: Development, repair, regeneration, and healing.

    PubMed

    Andarawis-Puri, Nelly; Flatow, Evan L; Soslowsky, Louis J

    2015-06-01

    Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions. Despite the prevalence of these injuries, a limited number of investigators are conducting fundamental, basic science studies focused on understanding processes governing tendinopathies and tendon healing. Development of effective therapeutics is hindered by the lack of fundamental guiding data on the biology of tendon development, signal transduction, mechanotransduction, and basic mechanisms underlying tendon pathogenesis and healing. To propel much needed progress, the New Frontiers in Tendon Research Conference, co-sponsored by NIAMS/NIH, the Orthopaedic Research Society, and the Icahn School of Medicine at Mount Sinai, was held to promote exchange of ideas between tendon researchers and basic science experts from outside the tendon field. Discussed research areas that are underdeveloped and represent major hurdles to the progress of the field will be presented in this review. To address some of these outstanding questions, conference discussions and breakout sessions focused on six topic areas (Cell Biology and Mechanics, Functional Extracellular Matrix, Development, Mechano-biology, Scarless Healing, and Mechanisms of Injury and Repair), which are reviewed in this special issue and briefly presented in this review. Review articles in this special issue summarize the progress in the field and identify essential new research directions. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  20. Basic Science Considerations in Primary Total Hip Replacement Arthroplasty

    PubMed Central

    Mirza, Saqeb B; Dunlop, Douglas G; Panesar, Sukhmeet S; Naqvi, Syed G; Gangoo, Shafat; Salih, Saif

    2010-01-01

    Total Hip Replacement is one of the most common operations performed in the developed world today. An increasingly ageing population means that the numbers of people undergoing this operation is set to rise. There are a numerous number of prosthesis on the market and it is often difficult to choose between them. It is therefore necessary to have a good understanding of the basic scientific principles in Total Hip Replacement and the evidence base underpinning them. This paper reviews the relevant anatomical and biomechanical principles in THA. It goes on to elaborate on the structural properties of materials used in modern implants and looks at the evidence base for different types of fixation including cemented and uncemented components. Modern bearing surfaces are discussed in addition to the scientific basis of various surface engineering modifications in THA prostheses. The basic science considerations in component alignment and abductor tension are also discussed. A brief discussion on modular and custom designs of THR is also included. This article reviews basic science concepts and the rationale underpinning the use of the femoral and acetabular component in total hip replacement. PMID:20582240

  1. Nutritional biology: a neglected basic discipline of nutritional science.

    PubMed

    Döring, Frank; Ströhle, Alexander

    2015-11-01

    On the basis of a scientific-philosophical analysis, this paper tries to show that the approaches in current nutritional science-including its subdisciplines which focus on molecular aspects-are predominantly application-oriented. This becomes particularly evident through a number of conceptual problems characterized by the triad of 'dearth of theoretical foundation,' 'particularist research questions,' and 'reductionist understanding of nutrition.' The thesis presented here is that an interpretive framework based on nutritional biology is able to shed constructive light on the fundamental problems of nutritional science. In this context, the establishment of 'nutritional biology' as a basic discipline in research and education would be a first step toward recognizing the phenomenon of 'nutrition' as an oecic process as a special case of an organism-environment interaction. Modern nutritional science should be substantively grounded on ecological-and therefore systems biology as well as organismic-principles. The aim of nutritional biology, then, should be to develop near-universal 'law statements' in nutritional science-a task which presents a major challenge for the current science system.

  2. Characteristics of physicians engaged in basic science: a questionnaire survey of physicians in basic science departments of a medical school in Japan.

    PubMed

    Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji

    2012-01-01

    The number of physicians engaged in basic science and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study aimed to determine the characteristics of physicians who are engaged in basic science in efforts to recruit talent. A questionnaire was distributed to all 30 physicians in the basic science departments of Juntendo University School of Medicine. Question items inquired about sex, years since graduation, years between graduation and time entering basic science, clinical experience, recommending the career to medical students, expected obstacles to students entering basic science, efforts to inspire students in research, increased number of lectures and practical training sessions on research, and career choice satisfaction. Correlations between the variables were examined using χ(2) tests. Overall, 26 physicians, including 7 female physicians, returned the questionnaire (response rate 86.7%). Most physicians were satisfied with their career choice. Medical students were deemed not to choose basic science as their future career, because they aimed to become clinicians and because they were concerned about salary. Women physicians in basic science departments were younger than men. Women physicians also considered themselves to make more efforts in inspiring medical students to be interested in research. Moreover, physicians who became basic scientists earlier in their career wanted more research-related lectures in medical education. Improving physicians' salaries in basic science is important to securing talent. In addition, basic science may be a good career path for women physicians to follow.

  3. Translational Science for Energy and Beyond.

    PubMed

    McKone, James R; Crans, Debbie C; Martin, Cheryl; Turner, John; Duggal, Anil R; Gray, Harry B

    2016-09-19

    A clear challenge for the coming decades is decreasing the carbon intensity of the global energy supply while simultaneously accommodating a rapid worldwide increase in power demand. Meeting this challenge of providing abundant, clean energy undoubtedly requires synergistic efforts between basic and applied researchers in the chemical sciences to develop and deploy new technologies. Among the available options, solar energy is one of the promising targets because of the high abundance of solar photons over much of the globe. Similarly, decarbonization of the global energy supply will require clean sources of hydrogen to use as reducing equivalents for fuel and chemical feedstocks. In this report, we discuss the importance of translational research-defined as work that explicitly targets basic discovery as well as technology development-in the context of photovoltaics and solar fuels. We focus on three representative research programs encompassing translational research in government, industry, and academia. We then discuss more broadly the benefits and challenges of translational research models and offer recommendations for research programs that address societal challenges in the energy sector and beyond.

  4. Translational Science for Energy and Beyond

    SciTech Connect

    McKone, James R.; Crans, Debbie C.; Martin, Cheryl; Turner, John; Duggal, Anil R.; Gray, Harry B.

    2016-09-19

    A clear challenge for the coming decades is decreasing the carbon intensity of the global energy supply while simultaneously accommodating a rapid worldwide increase in power demand. Meeting this challenge of providing abundant, clean energy undoubtedly requires synergistic efforts between basic and applied researchers in the chemical sciences to develop and deploy new technologies. Among the available options, solar energy is one of the promising targets because of the high abundance of solar photons over much of the globe. Similarly, decarbonization of the global energy supply will require clean sources of hydrogen to use as reducing equivalents for fuel and chemical feedstocks. In this report, we discuss the importance of translational research -- defined as work that explicitly targets basic discovery as well as technology development -- in the context of photovoltaics and solar fuels. We focus on three representative research programs encompassing translational research in government, industry, and academia. We then discuss more broadly the benefits and challenges of translational research models and offer recommendations for research programs that address societal challenges in the energy sector and beyond.

  5. Sustainable Energy for University Science Majors: Developing Guidelines for Educators

    ERIC Educational Resources Information Center

    Langbeheim, Elon; Rez, Peter

    2017-01-01

    This paper describes the basic tenets of a sustainable energy course for university science majors. First, it outlines the three core components of the course: (1) The scientific evidence for the connection between climate change and energy usage; (2) An analysis of the capacity and environmental impact of various renewable and traditional energy…

  6. The United Nations Basic Space Science Initiative for IHY 2007

    NASA Astrophysics Data System (ADS)

    Gopalswamy, N.; Davila, J. M.; Thompson, B. J.; Haubold, H.

    2006-08-01

    The United Nations, in cooperation with national and international space-related agencies and organizations, has been organizing annual workshops since 1990 on basic space science, particularly for the benefit of scientists and engineers from developing nations. The United Nations Office for Outer Space Affairs, through the IHY Secretariat and the United Nations Basic Space Science Initiative (UNBSSI) will assist scientists and engineers from all over the world in participating in the International Heliophysical Year (IHY) 2007. A major thrust of the IHY/UNBSSI program is to deploy arrays of small, inexpensive instruments such as magnetometers, radio telescopes, GPS receivers, all-sky cameras, etc. around the world to provide global measurements of ionospheric and heliospheric phenomena. The small instrument program is envisioned as a partnership between instrument providers, and instrument hosts in developing countries. The lead scientist will provide the instruments (or fabrication plans for instruments) in the array; the host country will provide manpower, facilities, and operational support to obtain data with the instrument typically at a local university. Funds are not available through the IHY to build the instruments; these must be obtained through the normal proposal channels. However all instrument operational support for local scientists, facilities, data acquisition, etc will be provided by the host nation. It is our hope that the IHY/UNBSSI program can facilitate the deployment of several of these networks world wide. Existing data bases and relevant software tools that can will be identified to promote space science activities in developing countries. Extensive data on space science have been accumulated by a number of space missions. Similarly, long-term data bases are available from ground based observations. These data can be utilized in ways different from originally intended for understanding the heliophysical processes. This paper provides an

  7. Computer animation and improved student comprehension of basic science concepts.

    PubMed

    Thatcher, Jack D

    2006-01-01

    Many medical students have difficulty learning basic science, either because they find the material challenging to comprehend or because they believe it has limited clinical application. Computer-assisted instruction (CAI)--ie, computer animation--can clarify instruction by allowing students to visualize complex, dynamic processes in an interesting presentation. At West Virginia School of Osteopathic Medicine (WVSOM) in Lewisburg, a series of computer animations have been developed to present concepts in molecular and cellular biology. The author conducted an investigation to compare the efficacy of one representative computer animation with that of traditional textbook material. The subjects were 22 students who had been admitted to WVSOM but who had not yet begun classes. The experimental design of the study consisted of a prelesson test, a lesson, and a postlesson test. The lesson explained the process of deoxyribonucleic acid (DNA) replication using either a computer animation (n=12) or a chapter from a textbook (n=10). Lesson comprehension as measured by the tests was significantly higher for subjects who used the computer animation than for subjects who used the textbook (P<.01). Furthermore, reviewing the text after studying with the computer animation did not raise test scores, suggesting that the animation was sufficient for learning and the text was unnecessary. After the study, a majority of subjects indicated a preference for the animation over the text. These results demonstrate that CAI can be an effective tool for relating basic science to medical students by improving comprehension and eliciting interest in the lessons.

  8. Basic Science Research and the Protection of Human Research Participants

    NASA Astrophysics Data System (ADS)

    Eiseman, Elisa

    2001-03-01

    Technological advances in basic biological research have been instrumental in recent biomedical discoveries, such as in the understanding and treatment of cancer, HIV/AIDS, and heart disease. However, many of these advances also raise several new ethical challenges. For example, genetic research may pose no physical risk beyond that of obtaining the initial blood sample, yet it can pose significant psychological and economic risks to research participants, such as stigmatization, discrimination in insurance and employment, invasion of privacy, or breach of confidentiality. These harms may occur even when investigators do not directly interact with the person whose DNA they are studying. Moreover, this type of basic research also raises broader questions, such as what is the definition of a human subject, and what kinds of expertise do Institutional Review Boards (IRBs) need to review the increasingly diverse types of research made possible by these advances in technology. The National Bioethics Advisory Commission (NBAC), a presidentially appointed federal advisory committee, has addressed these and other ethical, scientific and policy issues that arise in basic science research involving human participants. Two of its six reports, in particular, have proposed recommendations in this regard. "Research Involving Human Biological Materials: Ethical and Policy Guidance" addresses the basic research use of human tissues, cells and DNA and the protection of human participants in this type of research. In "Ethical and Policy Issues in the Oversight of Human Research" NBAC proposes a definition of research involving human participants that would apply to all scientific disciplines, including physical, biological, and social sciences, as well as the humanities and related professions, such as business and law. Both of these reports make it clear that the protection of research participants is key to conducting ethically sound research. By ensuring that all participants in

  9. New Science for a Secure and Sustainable Energy Future

    SciTech Connect

    2008-12-01

    Over the past five years, the Department of Energy's Office of Basic Energy Sciences has engaged thousands of scientists around the world to study the current status, limiting factors and specific fundamental scientific bottlenecks blocking the widespread implementation of alternate energy technologies. The reports from the foundational BESAC workshop, the ten 'Basic Research Needs' workshops and the panel on Grand Challenge science detail the necessary research steps (http://www.sc.doe.gov/bes/reports/list.html). This report responds to a charge from the Director of the Office of Science to the Basic Energy Sciences Advisory Committee to conduct a study with two primary goals: (1) to assimilate the scientific research directions that emerged from these workshop reports into a comprehensive set of science themes, and (2) to identify the new implementation strategies and tools required to accomplish the science. From these efforts it becomes clear that the magnitude of the challenge is so immense that existing approaches - even with improvements from advanced engineering and improved technology based on known concepts - will not be enough to secure our energy future. Instead, meeting the challenge will require fundamental understanding and scientific breakthroughs in new materials and chemical processes to make possible new energy technologies and performance levels far beyond what is now possible.

  10. Teaching energy using an integrated science approach

    NASA Astrophysics Data System (ADS)

    Poggi, Valeria; Miceli, Cristina; Testa, Italo

    2017-01-01

    Despite its relevance to all scientific domains, the debate surrounding the teaching of energy is still open. The main point remains the problems students have in understanding some aspects of the energy concept and in applying their knowledge to the comprehension of natural phenomena. In this paper, we present a research-based interdisciplinary approach to the teaching of energy in which the first and second laws of thermodynamics were used to interpret physical, chemical and biological processes. The contents of the three disciplines (physics, chemistry, biology) were reconstructed focusing on six basic aspects of energy (forms, transfer, transformation, conservation, degradation, and entropy) and using common teaching methodologies. The module was assessed with 39 secondary school students (aged 15-16) using a 30-question research instrument and a treatment/control group methodology. Analysis of students’ learning outcomes suggests a better understanding of the energy concept, supporting the effectiveness of an interdisciplinary approach in the teaching of energy in physics and science in general. Implications for the teaching of energy are briefly discussed.

  11. Defense, basic, and industrial research at the Los Alamos Neutron Science Center: Proceedings

    SciTech Connect

    Longshore, A.; Salgado, K.

    1995-10-01

    The Workshop on Defense, Basic, and Industrial Research at the Los Alamos Neutron Science Center gathered scientists from Department of Energy national laboratories, other federal institutions, universities, and industry to discuss the use of neutrons in science-based stockpile stewardship, The workshop began with presentations by government officials, senior representatives from the three weapons laboratories, and scientific opinion leaders. Workshop participants then met in breakout sessions on the following topics: materials science and engineering; polymers, complex fluids, and biomaterials; fundamental neutron physics; applied nuclear physics; condensed matter physics and chemistry; and nuclear weapons research. They concluded that neutrons can play an essential role in science-based stockpile stewardship and that there is overlap and synergy between defense and other uses of neutrons in basic, applied, and industrial research from which defense and civilian research can benefit. This proceedings is a collection of talks and papers from the plenary, technical, and breakout session presentations. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  12. Photon Science for Renewable Energy

    SciTech Connect

    Hussain, Zahid; Tamura, Lori; Padmore, Howard; Schoenlein, Bob; Bailey, Sue

    2010-03-31

    Our current fossil-fuel-based system is causing potentially catastrophic changes to our planet. The quest for renewable, nonpolluting sources of energy requires us to understand, predict, and ultimately control matter and energy at the electronic, atomic, and molecular levels. Light-source facilities - the synchrotrons of today and the next-generation light sources of tomorrow - are the scientific tools of choice for exploring the electronic and atomic structure of matter. As such, these photon-science facilities are uniquely positioned to jump-start a global revolution in renewable and carbonneutral energy technologies. In these pages, we outline and illustrate through examples from our nation's light sources possible scientific directions for addressing these profound yet urgent challenges.

  13. Truth in basic biomedical science will set future mankind free.

    PubMed

    Ling, Gilbert N

    2011-01-01

    It is self-evident that continued wellbeing and prosperity of our species in time to come depends upon a steady supply of major scientific and technologic innovations. However, major scientific and technical innovations are rare. As a rule, they grow only in the exceptionally fertile minds of men and women, who have fully mastered the underlying basic sciences. To waken their interest in science at an early critical age and to nurture and enhance that interest afterward, good textbooks at all level of education that accurately portray the relevant up-to-date knowledge are vital. As of now, the field of science that offers by far the greatest promise for the future of humanity is the science of life at the most basic cell and below-cell level. Unfortunately, it is precisely this crucial part of the (standardized) biological textbooks for all high schools and colleges in the US and abroad that have become, so to speak, fossilized. As a result, generation after generation of (educated) young men and women have been and are still being force-fed as established scientific truth an obsolete membrane (pump) theory, which has been categorically disproved half a century ago (see Endnote 1.) To reveal this Trojan horse of a theory for what it really is demands the concerted efforts of many courageous individuals especially young biology teachers who take themselves and their career seriously. But even the most courageous and the most resourceful won't find the task easy. To begin with, they would find it hard to access the critical scientific knowledge, with which to convert the skeptic and to rally the friendly. For the wealth of mutually supportive evidence against the membrane (pump) theory are often hidden in inaccessible publications and/or in languages other than English. To overcome this seemingly trivial but in fact formidable obstacle and to reveal the beauty and coherence of the existing but untaught truth, I put together in this small package a collection of the

  14. Integrating basic science without integrating basic scientists: reconsidering the place of individual teachers in curriculum reform.

    PubMed

    Hopkins, Robin; Pratt, Daniel; Bowen, Judith L; Regehr, Glenn

    2015-02-01

    The call for integration of the basic and clinical sciences plays prominently in recent conversations about curricular change in medical education; however, history shows that, like other concepts related to curricular reform, integration has been continually revisited, leading to incremental change but no meaningful transformation. To redress this cycle of "change without difference," the medical education community must reexamine the approach that dominates medical education reform efforts and explore alternative perspectives that may help to resolve the cyclical "problem" of recommending but not effecting integration. To provide a different perspective on implementing integration, the authors of this Perspective look to the domain of educational change as an approach to examining the transitions that occur within complex and evolving environments. This area of literature both acknowledges the multiple levels involved in change and emphasizes the need not only to address systemic structure but also to prioritize individuals during times of transition. The struggle to implement curricular integration in medical education may stem from the fact that reform efforts appear to focus largely on transformation at the level of curricular structure as opposed to considering what learning needs to occur at each level of change and highlighting the individual as the educational change literature suggests. To bring appropriate attention to the place of individual educators, especially basic scientists, the medical education community should explore how the mandate to integrate clinically relevant material may impact these faculty and the teaching of their domains.

  15. Using educational games to engage students in veterinary basic sciences.

    PubMed

    Buur, Jennifer L; Schmidt, Peggy L; Barr, Margaret C

    2013-01-01

    Educational games are an example of an active learning teaching technique based on Kolb's learning cycle. We have designed multiple games to provide concrete experiences for social groups of learners in the basic sciences. "Antimicrobial Set" is a card game that illustrates global patterns in antimicrobial therapy. "SHOCK!" is a card game designed to enhance student understanding of the four types of hypersensitivity reactions. After each game is played, students undergo a structured debriefing session with faculty members to further enhance their self-reflective skills. "Foodborne Outbreak Clue" utilizes the famous Parker Brothers® board game as a means to practice skills associated with outbreak investigation and risk assessment. This game is used as a review activity and fun application of epidemiologic concepts. Anecdotal feedback from students suggests that they enjoyed the activities. Games such as these can be easily implemented in large- or small-group settings and can be adapted to other disciplines as needed.

  16. Corneal gene therapy: basic science and translational perspective.

    PubMed

    Mohan, Rajiv R; Rodier, Jason T; Sharma, Ajay

    2013-07-01

    Corneal blindness is the third leading cause of blindness worldwide. Gene therapy is an emerging technology for corneal blindness due to the accessibility and immune-privileged nature of the cornea, ease of vector administration and visual monitoring, and ability to perform frequent noninvasive corneal assessment. Vision restoration by gene therapy is contingent upon vector and mode of therapeutic gene introduction into targeted cells/tissues. Numerous efficacious vectors, delivery techniques, and approaches have evolved in the last decade for developing gene-based interventions for corneal diseases. Maximizing the potential benefits of gene therapy requires efficient and sustained therapeutic gene expression in target cells, low toxicity, and a high safety profile. This review describes the basic science associated with many gene therapy vectors and the present progress of gene therapy carried out for various ocular surface disorders and diseases.

  17. Corneal Gene Therapy: Basic Science and Translational Perspective

    PubMed Central

    Mohan, Rajiv R.; Rodier, Jason T.; Sharma, Ajay

    2013-01-01

    Corneal blindness is the third leading cause of blindness worldwide. Gene therapy is an emerging technology for corneal blindness due to the accessibility and immune-privileged nature of the cornea, ease of vector administration and visual monitoring, and ability to perform frequent noninvasive corneal assessment. Vision restoration by gene therapy is contingent upon vector and mode of therapeutic gene introduction into targeted cells/tissues. Numerous efficacious vectors, delivery techniques, and approaches have evolved in last decade for developing gene-based interventions for corneal diseases. Maximizing the potential benefits of gene therapy requires efficient and sustained therapeutic gene expression in target cells, low toxicity, and a high safety profile. This review describes the basic science associated with many gene therapy vectors and the present progress of gene therapy carried out for various ocular surface disorders and diseases. PMID:23838017

  18. Molecular imaging: interaction between basic and clinical science.

    PubMed

    Atreya, Raja; Waldner, Maximilian J; Neurath, Markus F

    2010-12-01

    One of the major proceedings in the field of gastrointestinal endoscopy has been the advent of molecular imaging, which possesses the potential to have a significant effect on the existing diagnostic and therapeutic paradigms. Molecular imaging encompasses different methods that enable the visualization of disease-specific morphologic or functional alterations of the mucosa based on the molecular signature of individual cells. This development has been made possible by advancements in basic science coupled with technological innovations in endoscopy, both facilitating the identification and characterization of mucosal lesions in vivo based on the lesions' molecular composition rather than their morphologic structure alone. Novel studies based on fluorescent antibody imaging pave the road toward clinical translation and give hope for improved diagnosis and targeted therapies in gastrointestinal diseases.

  19. Cryotherapy of cardiac arrhythmia: From basic science to the bedside.

    PubMed

    Avitall, Boaz; Kalinski, Arthur

    2015-10-01

    This review focuses on the basic science of cellular destruction by tissue freezing and application of transvenous cryocatheter technology to treat cardiac arrhythmia. Ideally, foci for arrhythmias are selectively ablated, arrhythmogenic tissues are destroyed, and reentry circuits are bisected in order to silence adverse electrical activity, with the goal of restoring normal sinus rhythm. The mechanism of ablation using cryotherapy results in distinct lesion qualities advantageous to radiofrequency (Khairy P, Chauvet M, Lehman J, et al. Lower incidence of thrombus formation with cryoenergy versus radiofrequency catheter ablation. Circulation 2003;107:2045-2050). This review is devoted to the mechanism of cryoablation, postablation histopathological changes, and how this information should be used by the clinicians to improve safety and maximize ablation success. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  20. Attitude of Basic Science Medical Students Toward Interprofessional Collaboration.

    PubMed

    Shankar, P Ravi; Dwivedi, Neelam R; Nandy, Atanu; Balasubramanium, Ramanan

    2015-09-25

    Interprofessional collaboration (IPC) and interprofessional education (IPE) are increasingly emphasized in the education of health professions. Xavier University School of Medicine, a Caribbean medical school admits students from the United States, Canada, and other countries to the undergraduate medical course. The present study was carried out to obtain information about the attitude toward IPC among basic science medical students and note differences, if any, among different subgroups. The study was conducted among first to fifth semester students during July 2015 using the previously validated Jefferson Scale of Attitudes Toward Interprofessional Collaboration (JeffSATIC). Gender, age, semester, and nationality were noted. Participants' agreement with a set of 20 statements was studied. Mean total scores, working relationship, and accountability scores were calculated and compared among different subgroups of respondents (p<0.05). Sixty-seven of the 71 students (94.4%) participated. Cronbach's alpha value of the questionnaire was 0.827, indicating good internal consistency. The mean total score was 104.48 (maximum score 140) while the working relationship and accountability scores were 63.51 (maximum score 84) and 40.97 (maximum score 56), respectively. Total scores were significantly higher among third-semester students and students of Canadian nationality. Working relationship and accountability scores were higher among first and third-semester students. The total working relationship and accountability scores were lower compared to those obtained in a previous study. Opportunities for IPE and IPC during the basic science years should be strengthened. Longitudinal studies in the institution may be helpful. Similar studies in other Caribbean medical schools are required.

  1. Attitude of Basic Science Medical Students Toward Interprofessional Collaboration

    PubMed Central

    Dwivedi, Neelam R; Nandy, Atanu; Balasubramanium, Ramanan

    2015-01-01

    Purpose: Interprofessional collaboration (IPC) and interprofessional education (IPE) are increasingly emphasized in the education of health professions. Xavier University School of Medicine, a Caribbean medical school admits students from the United States, Canada, and other countries to the undergraduate medical course. The present study was carried out to obtain information about the attitude toward IPC among basic science medical students and note differences, if any, among different subgroups. Methods: The study was conducted among first to fifth semester students during July 2015 using the previously validated Jefferson Scale of Attitudes Toward Interprofessional Collaboration (JeffSATIC). Gender, age, semester, and nationality were noted. Participants’ agreement with a set of 20 statements was studied. Mean total scores, working relationship, and accountability scores were calculated and compared among different subgroups of respondents (p<0.05). Results: Sixty-seven of the 71 students (94.4%) participated. Cronbach’s alpha value of the questionnaire was 0.827, indicating good internal consistency. The mean total score was 104.48 (maximum score 140) while the working relationship and accountability scores were 63.51 (maximum score 84) and 40.97 (maximum score 56), respectively. Total scores were significantly higher among third-semester students and students of Canadian nationality. Working relationship and accountability scores were higher among first and third-semester students. Conclusion: The total working relationship and accountability scores were lower compared to those obtained in a previous study. Opportunities for IPE and IPC during the basic science years should be strengthened. Longitudinal studies in the institution may be helpful. Similar studies in other Caribbean medical schools are required. PMID:26543691

  2. Republished: A straightforward guide to the basic science behind arrhythmogenesis.

    PubMed

    Dumotier, Berengere M

    2015-04-01

    The underlying mechanisms behind cardiac arrhythmias are described in this manuscript. In clinical practice, significant arrhythmias are unpredictable, and under some conditions, potentially life-threatening. How can basic science help improve our understanding of molecular entities and factors behind the arrhythmia to advance, develop, adapt or deliver available medications? Structural heart disease and remodelling (e.g., heart failure, cardiomyopathy), the presence of modulating factors (i.e., diabetes mellitus, autonomic nervous system), genetic predispositions (i.e., channelopathies) are considerable preconditions, and influence the development of an arrhythmia. Cardiac arrhythmias may indeed share common basic mechanisms, while elements and substrates perpetuating these may be different and ultimately manifest as various ECG abnormalities. This article lists cellular and subcellular iatrogenic disorders responsible for abnormal impulse generation, or conduction disturbances, including the latest development in theories and biological research, for a better understanding of cellular disorders behind arrhythmogenesis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  3. Basic science breaks through: New therapeutic advances in Parkinson's disease.

    PubMed

    Brundin, Patrik; Atkin, Graham; Lamberts, Jennifer T

    2015-09-15

    Parkinson's disease (PD) is the second most common neurodegenerative disease and is typically associated with progressive motor dysfunction, although PD patients also exhibit a variety of non-motor symptoms. The neuropathological hallmark of PD is intraneuronal inclusions containing primarily α-Synuclein (α-Syn), and several lines of evidence point to α-Syn as a key contributor to disease progression. Thus, basic research in the field of PD is largely focused on understanding the pathogenic properties of α-Syn. Over the past 2 y, these studies helped to identify several novel therapeutic strategies that have the potential to slow PD progression; such strategies include sequestration of extracellular α-Syn through immunotherapy, reduction of α-Syn multimerization or intracellular toxicity, and attenuation of the neuroinflammatory response. This review describes these and other putative therapeutic strategies, together with the basic science research that led to their identification. The current breadth of novel targets for the treatment of PD warrants cautious optimism in the fight against this devastating disease. © 2015 International Parkinson and Movement Disorder Society.

  4. A straightforward guide to the basic science behind arrhythmogenesis.

    PubMed

    Dumotier, Berengere M

    2014-12-01

    The underlying mechanisms behind cardiac arrhythmias are described in this manuscript. In clinical practice, significant arrhythmias are unpredictable, and under some conditions, potentially life-threatening. How can basic science help improve our understanding of molecular entities and factors behind the arrhythmia to advance, develop, adapt or deliver available medications? Structural heart disease and remodelling (eg, heart failure, cardiomyopathy), the presence of modulating factors (ie, diabetes mellitus, autonomic nervous system), genetic predispositions (ie, channelopathies) are considerable preconditions, and influence the development of an arrhythmia. Cardiac arrhythmias may indeed share common basic mechanisms, while elements and substrates perpetuating these may be different and ultimately manifest as various ECG abnormalities. This article lists cellular and subcellular iatrogenic disorders responsible for abnormal impulse generation, or conduction disturbances, including the latest development in theories and biological research, for a better understanding of cellular disorders behind arrhythmogenesis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. Basic Teaching Units, BTU's on Energy. Nebraska Energy Conservation Plan.

    ERIC Educational Resources Information Center

    Lay, Gary A., Ed.; McCurdy, Donald, Ed.

    This collection of 21 teaching units is designed for use in energy education within various disciplines of the secondary curriculum. Each unit is designed to stand alone. Suggested teaching times range from five to fifteen days. No particular order of presentation is implied. Each unit is organized as follows: abstract, recommended level, time…

  6. Basic Teaching Units, BTU's on Energy. Nebraska Energy Conservation Plan.

    ERIC Educational Resources Information Center

    Lay, Gary A., Ed.; McCurdy, Donald, Ed.

    This collection of 21 teaching units is designed for use in energy education within various disciplines of the secondary curriculum. Each unit is designed to stand alone. Suggested teaching times range from five to fifteen days. No particular order of presentation is implied. Each unit is organized as follows: abstract, recommended level, time…

  7. Solar Energy Education. Renewable energy activities for junior high/middle school science

    SciTech Connect

    Not Available

    1985-01-01

    Some basic topics on the subject of solar energy are outlined in the form of a teaching manual. The manual is geared toward junior high or middle school science students. Topics include solar collectors, solar water heating, solar radiation, insulation, heat storage, and desalination. Instructions for the construction of apparatus to demonstrate the solar energy topics are provided. (BCS)

  8. 75 FR 65363 - Basic Behavioral and Social Science Opportunity Network (OppNet)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... HUMAN SERVICES National Institutes of Health Basic Behavioral and Social Science Opportunity Network... promote and publicize the Basic Behavioral and Social Science Opportunity Network (OppNet) initiative... Behavioral and Social Science Opportunity Network (OppNet) is a trans-NIH initiative to expand the...

  9. The Reorganization of Basic Science Departments in U.S. Medical Schools, 1980-1999.

    ERIC Educational Resources Information Center

    Mallon, William T.; Biebuyck, Julien F.; Jones, Robert F.

    2003-01-01

    Constructed a longitudinal database to examine how basic science departments have been reorganized at U.S. medical schools. Found that there were fewer basic science departments in the traditional disciplines of anatomy, biochemistry, microbiology, pharmacology, and physiology in 1999 than in 1980. But as biomedical science has developed in an…

  10. Alternative Methods by Which Basic Science Pharmacy Faculty Can Relate to Clinical Practice.

    ERIC Educational Resources Information Center

    Kabat, Hugh F.; And Others

    1982-01-01

    A panel of pharmacy faculty ranked a broad inventory of basic pharmaceutical science topics in terms of their applicability to clinical pharmacy practice. The panel concluded that basic pharmaceutical sciences are essentially applications of foundation areas in biological, physical, and social sciences. (Author/MLW)

  11. Alternative Methods by Which Basic Science Pharmacy Faculty Can Relate to Clinical Practice.

    ERIC Educational Resources Information Center

    Kabat, Hugh F.; And Others

    1982-01-01

    A panel of pharmacy faculty ranked a broad inventory of basic pharmaceutical science topics in terms of their applicability to clinical pharmacy practice. The panel concluded that basic pharmaceutical sciences are essentially applications of foundation areas in biological, physical, and social sciences. (Author/MLW)

  12. The Reorganization of Basic Science Departments in U.S. Medical Schools, 1980-1999.

    ERIC Educational Resources Information Center

    Mallon, William T.; Biebuyck, Julien F.; Jones, Robert F.

    2003-01-01

    Constructed a longitudinal database to examine how basic science departments have been reorganized at U.S. medical schools. Found that there were fewer basic science departments in the traditional disciplines of anatomy, biochemistry, microbiology, pharmacology, and physiology in 1999 than in 1980. But as biomedical science has developed in an…

  13. Basic ingredients of free energy calculations: a review.

    PubMed

    Christ, Clara D; Mark, Alan E; van Gunsteren, Wilfred F

    2010-06-01

    Methods to compute free energy differences between different states of a molecular system are reviewed with the aim of identifying their basic ingredients and their utility when applied in practice to biomolecular systems. A free energy calculation is comprised of three basic components: (i) a suitable model or Hamiltonian, (ii) a sampling protocol with which one can generate a representative ensemble of molecular configurations, and (iii) an estimator of the free energy difference itself. Alternative sampling protocols can be distinguished according to whether one or more states are to be sampled. In cases where only a single state is considered, six alternative techniques could be distinguished: (i) changing the dynamics, (ii) deforming the energy surface, (iii) extending the dimensionality, (iv) perturbing the forces, (v) reducing the number of degrees of freedom, and (vi) multi-copy approaches. In cases where multiple states are to be sampled, the three primary techniques are staging, importance sampling, and adiabatic decoupling. Estimators of the free energy can be classified as global methods that either count the number of times a given state is sampled or use energy differences. Or, they can be classified as local methods that either make use of the force or are based on transition probabilities. Finally, this overview of the available techniques and how they can be best used in a practical context is aimed at helping the reader choose the most appropriate combination of approaches for the biomolecular system, Hamiltonian and free energy difference of interest.

  14. Transition of Solvent Interaction Research from Basic Science to Applied Science.

    PubMed

    Arakawa, Tsutomu

    2016-01-01

    As a graduate course student, I studied the aggregation behavior of the wheat protein gluten, induced by changes in pH and ionic strength, thus beginning my research career in the field of solvent effects. The following 5 years were spent as a post-doctoral reseracher in the U.S., focused on protein-solvent interactions, which, according to my advisor, Dr. Timasheff, was too basic to be supported by academic grants. This study, however, answered a number of questions about how different solvents affect behavior of proteins in solution, e.g., a solubility behavior known as Hofmeister series. This research experience landed me an R&D position at a startup biotech company, Amgen, where knowledge on solvents played a fundamental role in protein refolding, formulation and chromatography. This demonstrates the unanticipated possibility that an un-funded, basic academic science study earlier can be transitioned later into an industrially-significant applied science.

  15. Basic Research Policy of the Department of Defense: Report of the Defense Science Board Task Force

    DTIC Science & Technology

    1968-02-20

    Classification) Basic Research Policy of the Department of Defense, Report of the Defense Science Board Task Force, UNCLASSIFIED 12 PERSONAL AUTHOR(S) N/A...obsolete. SECURITY CLASSIFICATION OF THIS PAGE — In wcnssrnw BASIC RESEARCH POLICY OF THE DEPARTMENT OF DEFENSE Report of the Defense Science Board Task...BOARD SUBJECT: Report of Task Force on Basic Research Policy The Task Force of the Defense Science Board, appointed at the request of the

  16. Myocardial ischemia reperfusion injury: from basic science to clinical bedside.

    PubMed

    Frank, Anja; Bonney, Megan; Bonney, Stephanie; Weitzel, Lindsay; Koeppen, Michael; Eckle, Tobias

    2012-09-01

    Myocardial ischemia reperfusion injury contributes to adverse cardiovascular outcomes after myocardial ischemia, cardiac surgery or circulatory arrest. Primarily, no blood flow to the heart causes an imbalance between oxygen demand and supply, named ischemia (from the Greek isch, restriction; and haema, blood), resulting in damage or dysfunction of the cardiac tissue. Instinctively, early and fast restoration of blood flow has been established to be the treatment of choice to prevent further tissue injury. Indeed, the use of thrombolytic therapy or primary percutaneous coronary intervention is the most effective strategy for reducing the size of a myocardial infarct and improving the clinical outcome. Unfortunately, restoring blood flow to the ischemic myocardium, named reperfusion, can also induce injury. This phenomenon was therefore termed myocardial ischemia reperfusion injury. Subsequent studies in animal models of acute myocardial infarction suggest that myocardial ischemia reperfusion injury accounts for up to 50% of the final size of a myocardial infarct. Consequently, many researchers aim to understand the underlying molecular mechanism of myocardial ischemia reperfusion injury to find therapeutic strategies ultimately reducing the final infarct size. Despite the identification of numerous therapeutic strategies at the bench, many of them are just in the process of being translated to bedside. The current review discusses the most striking basic science findings made during the past decades that are currently under clinical evaluation, with the ultimate goal to treat patients who are suffering from myocardial ischemia reperfusion-associated tissue injury.

  17. The HelCat basic plasma science device

    NASA Astrophysics Data System (ADS)

    Gilmore, M.; Lynn, A. G.; Desjardins, T. R.; Zhang, Y.; Watts, C.; Hsu, S. C.; Betts, S.; Kelly, R.; Schamiloglu, E.

    2015-01-01

    The Helicon-Cathode(HelCat) device is a medium-size linear experiment suitable for a wide range of basic plasma science experiments in areas such as electrostatic turbulence and transport, magnetic relaxation, and high power microwave (HPM)-plasma interactions. The HelCat device is based on dual plasma sources located at opposite ends of the 4 m long vacuum chamber - an RF helicon source at one end and a thermionic cathode at the other. Thirteen coils provide an axial magnetic field B >= 0.220 T that can be configured individually to give various magnetic configurations (e.g. solenoid, mirror, cusp). Additional plasma sources, such as a compact coaxial plasma gun, are also utilized in some experiments, and can be located either along the chamber for perpendicular (to the background magnetic field) plasma injection, or at one of the ends for parallel injection. Using the multiple plasma sources, a wide range of plasma parameters can be obtained. Here, the HelCat device is described in detail and some examples of results from previous and ongoing experiments are given. Additionally, examples of planned experiments and device modifications are also discussed.

  18. Pharmacology of heart failure: From basic science to novel therapies.

    PubMed

    Lother, Achim; Hein, Lutz

    2016-10-01

    Chronic heart failure is one of the leading causes for hospitalization in the United States and Europe, and is accompanied by high mortality. Current pharmacological therapy of chronic heart failure with reduced ejection fraction is largely based on compounds that inhibit the detrimental action of the adrenergic and the renin-angiotensin-aldosterone systems on the heart. More than one decade after spironolactone, two novel therapeutic principles have been added to the very recently released guidelines on heart failure therapy: the HCN-channel inhibitor ivabradine and the combined angiotensin and neprilysin inhibitor valsartan/sacubitril. New compounds that are in phase II or III clinical evaluation include novel non-steroidal mineralocorticoid receptor antagonists, guanylate cyclase activators or myosine activators. A variety of novel candidate targets have been identified and the availability of gene transfer has just begun to accelerate translation from basic science to clinical application. This review provides an overview of current pharmacology and pharmacotherapy in chronic heart failure at three stages: the updated clinical guidelines of the American Heart Association and the European Society of Cardiology, new drugs which are in clinical development, and finally innovative drug targets and their mechanisms in heart failure which are emerging from preclinical studies will be discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Basic science behind the cardiovascular benefits of exercise.

    PubMed

    Wilson, Mathew G; Ellison, Georgina M; Cable, N Tim

    2015-12-01

    Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause mortality, with increases in cardiorespiratory fitness associated with corresponding decreases in CV disease risk. The effects of exercise upon the myocardium and vascular system are dependent upon the frequency, intensity and duration of the exercise itself. Following a prolonged period (≥ 6 months) of regular intensive exercise in previously untrained individuals, resting and submaximal exercising heart rates are typically 5-20 beats lower, with an increase in stroke volume of ∼ 20% and enhanced myocardial contractility. Structurally, all four heart chambers increase in volume with mild increases in wall thickness, resulting in greater cardiac mass due to increased myocardial cell size. With this in mind, the present paper aims to review the basic science behind the CV benefits of exercise. Attention will be paid to understanding (1) the relationship between exercise and cardiac remodelling; (2) the cardiac cellular and molecular adaptations in response to exercise, including the examination of molecular mechanisms of physiological cardiac growth and applying these mechanisms to identify new therapeutic targets to prevent or reverse pathological remodelling and heart failure; and (3) vascular adaptations in response to exercise. Finally, this review will briefly examine how to optimise the CV benefits of exercise by considering how much and how intense exercise should be. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  20. Basic science behind the cardiovascular benefits of exercise.

    PubMed

    Wilson, Mathew G; Ellison, Georgina M; Cable, N Tim

    2015-05-15

    Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause mortality, with increases in cardiorespiratory fitness associated with corresponding decreases in CV disease risk. The effects of exercise upon the myocardium and vascular system are dependent upon the frequency, intensity and duration of the exercise itself. Following a prolonged period (≥6 months) of regular intensive exercise in previously untrained individuals, resting and submaximal exercising heart rates are typically 5-20 beats lower, with an increase in stroke volume of ∼20% and enhanced myocardial contractility. Structurally, all four heart chambers increase in volume with mild increases in wall thickness, resulting in greater cardiac mass due to increased myocardial cell size. With this in mind, the present paper aims to review the basic science behind the CV benefits of exercise. Attention will be paid to understanding (1) the relationship between exercise and cardiac remodelling; (2) the cardiac cellular and molecular adaptations in response to exercise, including the examination of molecular mechanisms of physiological cardiac growth and applying these mechanisms to identify new therapeutic targets to prevent or reverse pathological remodelling and heart failure; and (3) vascular adaptations in response to exercise. Finally, this review will briefly examine how to optimise the CV benefits of exercise by considering how much and how intense exercise should be. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. Basic science behind the cardiovascular benefits of exercise.

    PubMed

    Wilson, Mathew G; Ellison, Georgina M; Cable, N Tim

    2016-01-01

    Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause mortality, with increases in cardiorespiratory fitness associated with corresponding decreases in CV disease risk. The effects of exercise upon the myocardium and vascular system are dependent upon the frequency, intensity and duration of the exercise itself. Following a prolonged period (≥6 months) of regular intensive exercise in previously untrained individuals, resting and submaximal exercising heart rates are typically 5-20 beats lower, with an increase in stroke volume of ∼20% and enhanced myocardial contractility. Structurally, all four heart chambers increase in volume with mild increases in wall thickness, resulting in greater cardiac mass due to increased myocardial cell size. With this in mind, the present paper aims to review the basic science behind the CV benefits of exercise. Attention will be paid to understanding (1) the relationship between exercise and cardiac remodelling; (2) the cardiac cellular and molecular adaptations in response to exercise, including the examination of molecular mechanisms of physiological cardiac growth and applying these mechanisms to identify new therapeutic targets to prevent or reverse pathological remodelling and heart failure; and (3) vascular adaptations in response to exercise. Finally, this review will briefly examine how to optimise the CV benefits of exercise by considering how much and how intense exercise should be. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. Cancer Pharmacogenomics: Integrating Discoveries in Basic, Clinical and Population Sciences to Advance Predictive Cancer Care

    Cancer.gov

    Cancer Pharmacogenomics: Integrating Discoveries in Basic, Clinical and Population Sciences to Advance Predictive Cancer Care, a 2010 workshop sponsored by the Epidemiology and Genomics Research Program.

  3. Energy Activities for Junior High Science.

    ERIC Educational Resources Information Center

    Beaver, David; And Others

    This document is a collection of six energy education activities for junior high school science. Its purpose is to help promote knowledge about energy, provide laboratory experiences, provoke inquiry, and relate energy to society through the science curriculum. The six activities are designed to take one to three class periods. Two of the…

  4. Energy Activities for Junior High Science.

    ERIC Educational Resources Information Center

    Beaver, David; And Others

    This document is a collection of six energy education activities for junior high school science. Its purpose is to help promote knowledge about energy, provide laboratory experiences, provoke inquiry, and relate energy to society through the science curriculum. The six activities are designed to take one to three class periods. Two of the…

  5. Neutron Capture Reactions for Stockpile Stewardship and Basic Science

    SciTech Connect

    Parker, W; Agvaanluvsan, U; Becker, J; Wilk, P; Wu, C; Bredeweg, T; Couture, A; Haight, R; Jandel, M; O'Donnell, J; Reifarth, R; Rundberg, R; Ullmann, J; Vieira, D; Wouters, J; Sheets, S; Mitchell, G; Becvar, F; Krticka, M

    2007-08-04

    The capture process is a nuclear reaction in which a target atom captures an incident projectile, e.g. a neutron. The excited-state compound nucleus de-excites by emitting photons. This process creates an atom that has one more neutron than the target atom, so it is a different isotope of the same element. With low energy (slow) neutron projectiles, capture is the dominant reaction, other than elastic scattering. However, with very heavy nuclei, fission competes with capture as a method of de-excitation of the compound nucleus. With higher energy (faster) incident neutrons, additional reactions are also possible, such as emission of protons or emission of multiple neutrons. The probability of a particular reaction occurring (such as capture) is referred to as the cross section for that reaction. Cross sections are very dependent on the incoming neutron's energy. Capture reactions can be studied either using monoenergetic neutron sources or 'white' neutron sources. A 'white' neutron source has a wide range of neutron energies in one neutron beam. The advantage to the white neutron source is that it allows the study of cross sections as they depend on neutron energies. The Los Alamos Neutron Science Center, located at Los Alamos National Laboratory, provides an intense white neutron source. Neutrons there are created by a high-energy proton beam from a linear accelerator striking a heavy metal (tungsten) target. The neutrons range in energy from subthermal up to very fast - over 100 MeV in energy. Low-energy neutron reaction cross sections fluctuate dramatically from one target to another, and they are very difficult to predict by theoretical modeling. The cross sections for particular capture reactions are important for defense sciences, advanced reactor concepts, transmutation of radioactive wastes and nuclear astrophysics. We now have a strong collaboration between Lawrence Livermore National Laboratory, Los Alamos National Laboratory, North Carolina State

  6. In defense of basic science funding: today's scientific discovery is tomorrow's medical advance.

    PubMed

    Tessier-Lavigne, Marc

    2013-06-01

    In this address, I will discuss the importance of basic science in tackling our health problems. I will also describe how the funding cuts are damaging our economic competitiveness and turning our young people away from science.

  7. Back to the basic sciences: an innovative approach to teaching senior medical students how best to integrate basic science and clinical medicine.

    PubMed

    Spencer, Abby L; Brosenitsch, Teresa; Levine, Arthur S; Kanter, Steven L

    2008-07-01

    Abraham Flexner persuaded the medical establishment of his time that teaching the sciences, from basic to clinical, should be a critical component of the medical student curriculum, thus giving rise to the "preclinical curriculum." However, students' retention of basic science material after the preclinical years is generally poor. The authors believe that revisiting the basic sciences in the fourth year can enhance understanding of clinical medicine and further students' understanding of how the two fields integrate. With this in mind, a return to the basic sciences during the fourth year of medical school may be highly beneficial. The purpose of this article is to (1) discuss efforts to integrate basic science into the clinical years of medical student education throughout the United States and Canada, and (2) describe the highly developed fourth-year basic science integration program at the University of Pittsburgh School of Medicine. In their critical review of medical school curricula of 126 U.S. and 17 Canadian medical schools, the authors found that only 19% of U.S. medical schools and 24% of Canadian medical schools require basic science courses or experiences during the clinical years, a minor increase compared with 1985. Curricular methods ranged from simple lectures to integrated case studies with hands-on laboratory experience. The authors hope to advance the national discussion about the need to more fully integrate basic science teaching throughout all four years of the medical student curriculum by placing a curricular innovation in the context of similar efforts by other U.S. and Canadian medical schools.

  8. Science as Knowledge, Practice, and Map Making: The Challenge of Defining Metrics for Evaluating and Improving DOE-Funded Basic Experimental Science

    SciTech Connect

    Bodnarczuk, M.

    1993-03-01

    Industrial R&D laboratories have been surprisingly successful in developing performance objectives and metrics that convincingly show that planning, management, and improvement techniques can be value-added to the actual output of R&D organizations. In this paper, I will discuss the more difficult case of developing analogous constructs for DOE-funded non-nuclear, non-weapons basic research, or as I will refer to it - basic experimental science. Unlike most industrial R&D or the bulk of applied science performed at the National Renewable Energy Laboratory (NREL), the purpose of basic experimental science is producing new knowledge (usually published in professional journals) that has no immediate application to the first link (the R) of a planned R&D chain. Consequently, performance objectives and metrics are far more difficult to define. My claim is that if one can successfully define metrics for evaluating and improving DOE-funded basic experimental science (which is the most difficult case), then defining such constructs for DOE-funded applied science should be much less problematic. With the publication of the DOE Standard - Implementation Guide for Quality Assurance Programs for Basic and Applied Research (DOE-ER-STD-6001-92) and the development of a conceptual framework for integrating all the DOE orders, we need to move aggressively toward the threefold next phase: (1) focusing the management elements found in DOE-ER-STD-6001-92 on the main output of national laboratories - the experimental science itself; (2) developing clearer definitions of basic experimental science as practice not just knowledge; and (3) understanding the relationship between the metrics that scientists use for evaluating the performance of DOE-funded basic experimental science, the management elements of DOE-ER-STD-6001-92, and the notion of continuous improvement.

  9. Japanese medical students' interest in basic sciences: a questionnaire survey of a medical school in Japan.

    PubMed

    Yamazaki, Yuka; Uka, Takanori; Shimizu, Haruhiko; Miyahira, Akira; Sakai, Tatsuo; Marui, Eiji

    2013-02-01

    The number of physicians engaged in basic sciences and teaching is sharply decreasing in Japan. To alleviate this shortage, central government has increased the quota of medical students entering the field. This study investigated medical students' interest in basic sciences in efforts to recruit talent. A questionnaire distributed to 501 medical students in years 2 to 6 of Juntendo University School of Medicine inquired about sex, grade, interest in basic sciences, interest in research, career path as a basic science physician, faculties' efforts to encourage students to conduct research, increases in the number of lectures, and practical training sessions on research. Associations between interest in basic sciences and other variables were examined using χ(2) tests. From among the 269 medical students (171 female) who returned the questionnaire (response rate 53.7%), 24.5% of respondents were interested in basic sciences and half of them considered basic sciences as their future career. Obstacles to this career were their original aim to become a clinician and concerns about salary. Medical students who were likely to be interested in basic sciences were fifth- and sixth-year students, were interested in research, considered basic sciences as their future career, considered faculties were making efforts to encourage medical students to conduct research, and wanted more research-related lectures. Improving physicians' salaries in basic sciences is important for securing talent. Moreover, offering continuous opportunities for medical students to experience research and encouraging advanced-year students during and after bedside learning to engage in basic sciences are important for recruiting talent.

  10. Basic Research in Predictability Science as it Relates to the National Earth System Prediction Capability

    NASA Astrophysics Data System (ADS)

    Harr, P.

    2016-12-01

    The support of basic research in the atmospheric sciences by the National Science Foundation (NSF) has been balanced in relation to process and properties that span space and time scales associated with atmospheric dynamics, chemistry, physics, and thermodynamics. Because of the direct impact of the atmosphere on nearly every aspect of society, research in atmospheric science has deep roots in support of the advancement of knowledge for societal benefit. Indeed, increased knowledge of key atmospheric processes in conjunction with development of the means to incorporate that understanding into increasingly complex numerical models has provided for more accurate analyses and predictions of weather and climate. However, continued advancements in Earth-system modeling require increased knowledge of properties and processes occurring in and coupling among the atmosphere, ocean, land, cryosphere, and near-space environments. In a basic research construct, the study of predictability science is related to incomplete knowledge of properties and processes, model errors, and sensitivities to initial conditions. The NSF efforts in support of research to increase knowledge of Earth-system predictability can be placed into the context of the National Strategic Computing Initiative (NSCI, http://www.nsf.gov/nsci), in which NSF is one of three lead agencies with the Department of Energy and the Department of Defense. Leverage of the NSCI goals that aim to increase the technology base used for modeling and simulation; define a path toward a viable high-performance computing (HPC) capabilities; and increase the capacity and capability of a HPC ecosystem that includes enduring public-private partnerships, will support research into the three components of predictability science defined above. As the NSCI efforts increase, it is expected that NSF will lead advances predictability science for the benefit the national Earth System Prediction Capability.

  11. Science Awareness and Science Literacy through the Basic Physics Course: Physics with a bit of Metaphysics?

    NASA Astrophysics Data System (ADS)

    Rusli, Aloysius

    2016-08-01

    Until the 1980s, it is well known and practiced in Indonesian Basic Physics courses, to present physics by its effective technicalities: The ideally elastic spring, the pulley and moving blocks, the thermodynamics of ideal engine models, theoretical electrostatics and electrodynamics with model capacitors and inductors, wave behavior and its various superpositions, and hopefully closed with a modern physics description. A different approach was then also experimented with, using the Hobson and Moore texts, stressing the alternative aim of fostering awareness, not just mastery, of science and the scientific method. This is hypothesized to be more in line with the changed attitude of the so-called Millenials cohort who are less attentive if not interested, and are more used to multi-tasking which suits their shorter span of attention. The upside is increased awareness of science and the scientific method. The downside is that they are getting less experience of the scientific method which intensely bases itself on critical observation, analytic thinking to set up conclusions or hypotheses, and checking consistency of the hypotheses with measured data. Another aspect is recognition that the human person encompasses both the reasoning capacity and the mental- spiritual-cultural capacity. This is considered essential, as the world grows even smaller due to increased communication capacity, causing strong interactions, nonlinear effects, and showing that value systems become more challenging and challenged due to physics / science and its cosmology, which is successfully based on the scientific method. So students should be made aware of the common basis of these two capacities: the assumptions, the reasoning capacity and the consistency assumption. This shows that the limits of science are their set of basic quantifiable assumptions, and the limits of the mental-spiritual-cultural aspects of life are their set of basic metaphysical (non-quantifiable) assumptions. The

  12. Acquisition of Basic Science Process Skills among Malaysian Upper Primary Students

    ERIC Educational Resources Information Center

    Ong, Eng Tek; Ramiah, Puspa; Ruthven, Kenneth; Salleh, Sabri Mohd; Yusuff, Nik Azmah Nik; Mokhsein, Siti Eshah

    2015-01-01

    This study aims to determine whether there are significant differences in the acquisition of basic science process skills by gender, school location and by grade levels among upper primary school students. Using an established 36-item Basic Science Process Skills test that assesses the skills of observing, communicating, classifying, measuring,…

  13. A Simulation for Teaching the Basic and Clinical Science of Fluid Therapy

    ERIC Educational Resources Information Center

    Rawson, Richard E.; Dispensa, Marilyn E.; Goldstein, Richard E.; Nicholson, Kimberley W.; Vidal, Noni Korf

    2009-01-01

    The course "Management of Fluid and Electrolyte Disorders" is an applied physiology course taught using lectures and paper-based cases. The course approaches fluid therapy from both basic science and clinical perspectives. While paper cases provide a basis for application of basic science concepts, they lack key components of genuine clinical…

  14. Basic Pharmaceutical Sciences Examination as a Predictor of Student Performance during Clinical Training.

    ERIC Educational Resources Information Center

    Fassett, William E.; Campbell, William H.

    1984-01-01

    A comparison of Basic Pharmaceutical Sciences Examination (BPSE) results with student performance evaluations in core clerkships, institutional and community externships, didactic and clinical courses, and related basic science coursework revealed the BPSE does not predict student performance during clinical instruction. (MSE)

  15. Progress in the Utilization of High-Fidelity Simulation in Basic Science Education

    ERIC Educational Resources Information Center

    Helyer, Richard; Dickens, Peter

    2016-01-01

    High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress.

  16. Acquisition of Basic Science Process Skills among Malaysian Upper Primary Students

    ERIC Educational Resources Information Center

    Ong, Eng Tek; Ramiah, Puspa; Ruthven, Kenneth; Salleh, Sabri Mohd; Yusuff, Nik Azmah Nik; Mokhsein, Siti Eshah

    2015-01-01

    This study aims to determine whether there are significant differences in the acquisition of basic science process skills by gender, school location and by grade levels among upper primary school students. Using an established 36-item Basic Science Process Skills test that assesses the skills of observing, communicating, classifying, measuring,…

  17. A Simulation for Teaching the Basic and Clinical Science of Fluid Therapy

    ERIC Educational Resources Information Center

    Rawson, Richard E.; Dispensa, Marilyn E.; Goldstein, Richard E.; Nicholson, Kimberley W.; Vidal, Noni Korf

    2009-01-01

    The course "Management of Fluid and Electrolyte Disorders" is an applied physiology course taught using lectures and paper-based cases. The course approaches fluid therapy from both basic science and clinical perspectives. While paper cases provide a basis for application of basic science concepts, they lack key components of genuine clinical…

  18. Progress in the utilization of high-fidelity simulation in basic science education.

    PubMed

    Helyer, Richard; Dickens, Peter

    2016-06-01

    High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress. Copyright © 2016 The American Physiological Society.

  19. Progress in the Utilization of High-Fidelity Simulation in Basic Science Education

    ERIC Educational Resources Information Center

    Helyer, Richard; Dickens, Peter

    2016-01-01

    High-fidelity patient simulators are mainly used to teach clinical skills and remain underutilized in teaching basic sciences. This article summarizes our current views on the use of simulation in basic science education and identifies pitfalls and opportunities for progress.

  20. The Role of Basic Sciences in Patient Care and Clinical Teaching.

    ERIC Educational Resources Information Center

    White, Raymond P.

    1986-01-01

    More can be done to incorporate basic biological science into clinical dental teaching, including increased early basic science instruction by clinical faculty, establishment of departments of oral biology, the grand rounds format, case presentation in clinical settings, and continuing education involving practicing dentists and dental students.…

  1. Back to Basics for Science Teachers in Rural India.

    ERIC Educational Resources Information Center

    Waldron, Nick

    1998-01-01

    Describes how practical science can be taught using locally-collected junk materials and encourages a new approach to science teaching in rural India. Emphasizes science relevant to the villages to which children will return to when they leave school. (DDR)

  2. Exploring cognitive integration of basic science and its effect on diagnostic reasoning in novices.

    PubMed

    Lisk, Kristina; Agur, Anne M R; Woods, Nicole N

    2016-06-01

    Integration of basic and clinical science knowledge is increasingly being recognized as important for practice in the health professions. The concept of 'cognitive integration' places emphasis on the value of basic science in providing critical connections to clinical signs and symptoms while accounting for the fact that clinicians may not spontaneously articulate their use of basic science knowledge in clinical reasoning. In this study we used a diagnostic justification test to explore the impact of integrated basic science instruction on novices' diagnostic reasoning process. Participants were allocated to an integrated basic science or clinical science training group. The integrated basic science group was taught the clinical features along with the underlying causal mechanisms of four musculoskeletal pathologies while the clinical science group was taught only the clinical features. Participants completed a diagnostic accuracy test immediately after initial learning, and one week later a diagnostic accuracy and justification test. The results showed that novices who learned the integrated causal mechanisms had superior diagnostic accuracy and better understanding of the relative importance of key clinical features. These findings further our understanding of cognitive integration by providing evidence of the specific changes in clinical reasoning when basic and clinical sciences are integrated during learning.

  3. Connecting Science and Society: Basic Research in the Service of Social Objectives

    NASA Astrophysics Data System (ADS)

    Sonnert, Gerhard

    2007-03-01

    A flawed dichotomy of basic versus applied science (or of ``curiosity-driven'' vs. ``mission-oriented'' science) pervades today's thinking about science policy. This talk argues for the addition of a third mode of scientific research, called Jeffersonian science. Whereas basic science, as traditionally understood, is a quest for the unknown regardless of societal needs, and applied science is known science applied to known needs, Jeffersonian science is the quest for the unknown in the service of a known social need. It is research in an identified area of basic scientific ignorance that lies at the heart of a social problem. The talk discusses the conceptual foundations and then provides some case examples of Jeffersonian-type science initiatives, such as the Lewis and Clark Expedition, initiated by Thomas Jefferson (which led us to call this mode of research Jeffersonian), research conducted under the auspices of the National Institutes of Health, and a science policy project by President Jimmy Carter and his Science Adviser, Frank Press, in the late 1970s. Because the concept of Jeffersonian science explicitly ties basic research to the social good, one of the potential benefits of adding a Jeffersonian dimension to our thinking about science is that it might make science careers more attractive to women and underrepresented minorities.

  4. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Presented are 10 science energy education units designed to help students learn how to turn science questions and problems about energy into experiments. Each unit focuses on subject-matter knowledge and on the logic and strategy of scientific problem solving. These teacher-oriented materials include an overview of each unit, background…

  5. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Presented are 10 science energy education units designed to help students learn how to turn science questions and problems about energy into experiments. Each unit focuses on subject-matter knowledge and on the logic and strategy of scientific problem solving. These teacher-oriented materials include an overview of each unit, background…

  6. Basic science research in pediatric radiology - how to empower the leading edge of our field.

    PubMed

    Daldrup-Link, Heike E

    2014-08-01

    Basic science research aims to explore, understand and predict phenomena in the natural world. It spurs the discovery of fundamentally new principles and leads to new knowledge and new concepts. By comparison, applied research employs basic science knowledge toward practical applications. In the clinical realm, basic science research and applied research should be closely connected. Basic science discoveries can build the foundation for a broad range of practical applications and thereby bring major benefits to human health, education, environment and economy. This article explains how basic science research impacts our field, it describes examples of new research directions in pediatric imaging and it outlines current challenges that we need to overcome in order to enable the next groundbreaking discovery.

  7. Development and Validation of the Life Sciences Assessment: A Measure of Preschool Children's Conceptions of Basic Life Sciences

    ERIC Educational Resources Information Center

    Maherally, Uzma Nooreen

    2014-01-01

    The purpose of this study was to develop and validate a science assessment tool termed the Life Sciences Assessment (LSA) in order to assess preschool children's conceptions of basic life sciences. The hypothesis was that the four sub-constructs, each of which can be measured through a series of questions on the LSA, will make a significant…

  8. Development and Validation of the Life Sciences Assessment: A Measure of Preschool Children's Conceptions of Basic Life Sciences

    ERIC Educational Resources Information Center

    Maherally, Uzma Nooreen

    2014-01-01

    The purpose of this study was to develop and validate a science assessment tool termed the Life Sciences Assessment (LSA) in order to assess preschool children's conceptions of basic life sciences. The hypothesis was that the four sub-constructs, each of which can be measured through a series of questions on the LSA, will make a significant…

  9. Teachers' Involvement in Implementing the Basic Science and Technology Curriculum of the Nine-Year Basic Education

    ERIC Educational Resources Information Center

    Odili, John Nwanibeze; Ebisine, Sele Sylvester; Ajuar, Helen Nwakaife

    2011-01-01

    The study investigated teachers' involvement in implementing the basic science and technology curriculum in primary schools in WSLGA (Warri South Local Government Area) of Delta State. It sought to identify the availability of the document in primary schools and teachers' knowledge of the objectives and activities specified in the curriculum.…

  10. Summary of basic science activities at the European Society of Cardiology Congress in Barcelona 2014.

    PubMed

    Thum, Thomas

    2014-12-01

    With >35 000 participants, the European Society of Cardiology (ESC) congress was one of the biggest ESC events ever and basic science activities were well implemented. I here summarize the basic science activities during the congress. This includes a section 'Basic science activities in a nutshell' summarizing the most important sessions as well as 'Emerging science activities in the ESC' section with special focus on novel research fields such as the characterization of long non-coding RNAs in cardiovascular research. © 2015 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

  11. Fragility and basic process energies in vitrifying systems

    PubMed Central

    Martinez-Garcia, Julio Cesar; Rzoska, Sylwester J.; Drozd-Rzoska, Aleksandra; Starzonek, Szymon; Mauro, John C.

    2015-01-01

    The concept of ‘fragility’ constitutes a central point of the glass transition science serving as the ‘universal’ metric linking previtreous dynamics of qualitatively distinct systems. Finding the fundamental meaning of fragility is the ‘condicio sine qua’ for reaching the long expected conceptual breakthrough in this domain. This report shows that fragility is determined by the ratio between two fundamental process energies, viz. the activation enthalpy and activation energy. The reasoning, avoiding any underlying physical model, is supported by the experimental evidence ranging from low molecular weight liquids and polymers to plastic crystals and liquid crystals. All these lead to the new general scaling plot for dynamics of arbitrary glass former. The limited adequacy of broadly used so far semi-empirical relationships between fragility and the activation energy is shown. Results presented remain valid for an arbitrary complex system and collective phenomena if their dynamics is described by the general super-Arrhenius relation. PMID:25660971

  12. Laser-driven electron beam and radiation sources for basic, medical and industrial sciences.

    PubMed

    Nakajima, Kazuhisa

    2015-01-01

    To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker's review article on "Laser Acceleration and its future" [Toshiki Tajima, (2010)],(1)) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated.

  13. Laser-driven electron beam and radiation sources for basic, medical and industrial sciences

    PubMed Central

    NAKAJIMA, Kazuhisa

    2015-01-01

    To date active research on laser-driven plasma-based accelerators have achieved great progress on production of high-energy, high-quality electron and photon beams in a compact scale. Such laser plasma accelerators have been envisaged bringing a wide range of applications in basic, medical and industrial sciences. Here inheriting the groundbreaker’s review article on “Laser Acceleration and its future” [Toshiki Tajima, (2010)],1) we would like to review recent progress of producing such electron beams due to relativistic laser-plasma interactions followed by laser wakefield acceleration and lead to the scaling formulas that are useful to design laser plasma accelerators with controllability of beam energy and charge. Lastly specific examples of such laser-driven electron/photon beam sources are illustrated. PMID:26062737

  14. Energy Convertors. Third World Science.

    ERIC Educational Resources Information Center

    Jones, Natalie; Hughes, Wyn

    This unit, developed by the Third World Science Project, is designed to add a multicultural element to existing science syllabi (for students aged 11-16) in the United Kingdom. The project seeks to develop an appreciation of the: boundless fascination of the natural world; knowledge, skills, and expertise possessed by men/women everywhere;…

  15. Energy Convertors. Third World Science.

    ERIC Educational Resources Information Center

    Jones, Natalie; Hughes, Wyn

    This unit, developed by the Third World Science Project, is designed to add a multicultural element to existing science syllabi (for students aged 11-16) in the United Kingdom. The project seeks to develop an appreciation of the: boundless fascination of the natural world; knowledge, skills, and expertise possessed by men/women everywhere;…

  16. The Relationship between Immediate Relevant Basic Science Knowledge and Clinical Knowledge: Physiology Knowledge and Transthoracic Echocardiography Image Interpretation

    ERIC Educational Resources Information Center

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-01-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent…

  17. The Relationship between Immediate Relevant Basic Science Knowledge and Clinical Knowledge: Physiology Knowledge and Transthoracic Echocardiography Image Interpretation

    ERIC Educational Resources Information Center

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-01-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent…

  18. The Impact of Hands-On-Approach on Student Academic Performance in Basic Science and Mathematics

    ERIC Educational Resources Information Center

    Ekwueme, Cecilia O.; Ekon, Esther E.; Ezenwa-Nebife, Dorothy C.

    2015-01-01

    Children can learn mathematics and sciences effectively even before being exposed to formal school curriculum if basic Mathematics and Sciences concepts are communicated to them early using activity oriented (Hands-on) method of teaching. Mathematics and Science are practical and activity oriented and can best be learnt through inquiry (Okebukola…

  19. Growth in Turkish Positive Basic Sciences, 1933-1966.

    ERIC Educational Resources Information Center

    Ozinonu, A. Kemal

    This study collected data on the measurable qualities of Turkish science in terms of high level scientific manpower, scientific productivity, and scientific fertility from 1933 to 1966 and analyzed the data collected with the goal of providing a deeper understanding of the nature of Turkish science. Scientific personnel, including Turkish…

  20. Analysis of the basic science section of the orthopaedic in-training examination.

    PubMed

    Sheibani-Rad, Shahin; Arnoczky, Steven Paul; Walter, Norman E

    2012-08-01

    Since 1963, the Orthopaedic In-Training Examination (OITE) has been administered to orthopedic residents to assess residents' knowledge and measure the quality of teaching within individual programs. The OITE currently consists of 275 questions divided among 12 domains. This study analyzed all OITE basic science questions between 2006 and 2010. The following data were recorded: number of questions, question taxonomy, category of question, type of imaging modality, and recommended journal and book references. Between 2006 and 2010, the basic science section constituted 12.2% of the OITE. The assessment of taxonomy classification showed that recall-type questions were the most common, at 81.4%. Imaging modalities typically involved questions on radiographs and constituted 6.2% of the OITE basic science section. The majority of questions were basic science questions (eg, genetics, cell replication, and bone metabolism), with an average of 26.4 questions per year. The Journal of Bone & Joint Surgery (American Volume) and the American Academy of Orthopaedic Surgeons' Orthopaedic Basic Science were the most commonly and consistently cited journal and review book, respectively. This study provides the first review of the question content and recommended references of the OITE basic science section. This information will provide orthopedic trainees, orthopedic residency programs, and the American Academy of Orthopaedic Surgeons Evaluation Committee valuable information related to improving residents' knowledge and performance and optimizing basic science educational curricula. Copyright 2012, SLACK Incorporated.

  1. Basic science research and education: a priority for training and capacity building in developing countries.

    PubMed

    Deckelbaum, Richard J; Ntambi, James M; Wolgemuth, Debra J

    2011-09-01

    This article provides evidence that basic science research and education should be key priorities for global health training, capacity building, and practice. Currently, there are tremendous gaps between strong science education and research in developed countries (the North) as compared to developing countries (the South). In addition, science research and education appear as low priorities in many developing countries. The need to stress basic science research beyond the typical investment of infectious disease basic service and research laboratories in developing areas is significant in terms of the benefits, not only to education, but also for economic strengthening and development of human resources. There are some indications that appreciation of basic science research education and training is increasing, but this still needs to be applied more rigorously and strengthened systematically in developing countries. Copyright © 2011 Elsevier Inc. All rights reserved.

  2. Basic research needs and priorities in solar energy. Volume II. Technology crosscuts for DOE

    SciTech Connect

    Jayadev, J S; Roessner, D

    1980-01-01

    Priorities for basic research important to the future developments of solar energy are idenified, described, and recommended. SERI surveyed more than 120 leading scientists who were engaged in or knowledgeable of solar-related research. The result is an amalgam of national scientific opinion representing the views of key researchers in relevant disciplines and of SERI staff members. The scientific disciplines included in the report are: chemistry, biology, materials sciences, engineering and mathematics, and the social and behavioral sciences. Each discipline is subdivided into two to five topical areas-and, within each topical area, research needs are described and ranked according to the priorities suggested in the survey. Three categories of priority were established: crucial, important, and needed. A narrative accompanying the description of research needs in each topical area discusses the importance of research in the area for solar energy development and presents the bases for the priority rankings recommended.

  3. Science, Volume 184 Number 4134. Energy.

    ERIC Educational Resources Information Center

    Abelson, Philip H., Ed.

    1974-01-01

    This entire issue of the "Science" journal is devoted to the topic of energy and issues relating to the energy crisis. Its content was chosen to present material relevant to important public decisions of the next few years. Twenty-six articles cover a wide range of topics, including the impact of the energy crisis on people and…

  4. Science, Volume 184 Number 4134. Energy.

    ERIC Educational Resources Information Center

    Abelson, Philip H., Ed.

    1974-01-01

    This entire issue of the "Science" journal is devoted to the topic of energy and issues relating to the energy crisis. Its content was chosen to present material relevant to important public decisions of the next few years. Twenty-six articles cover a wide range of topics, including the impact of the energy crisis on people and…

  5. Teaching Basic Science Environmentally, The Concept: The cell is basic unit of structure of most organisms.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1985-01-01

    Suggests simple ways to introduce students to the concept that the cell is the basic unit of structure of most organisms. Mentions materials for microscope study that are readily available and easy to handle, e.g., membranes from between the scales of the onion bulb, thin-leaved plants, pond water, and pollen. (JHZ)

  6. Teaching Basic Science Environmentally, The Concept: The cell is basic unit of structure of most organisms.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1985-01-01

    Suggests simple ways to introduce students to the concept that the cell is the basic unit of structure of most organisms. Mentions materials for microscope study that are readily available and easy to handle, e.g., membranes from between the scales of the onion bulb, thin-leaved plants, pond water, and pollen. (JHZ)

  7. Nutrition--A Basic Strand of School Science.

    ERIC Educational Resources Information Center

    Yager, Robert E.

    1981-01-01

    The need for nutrition education to be given higher priority in science instruction in today's world is promoted. Nutrition is viewed as a significant problem for all persons in a personal sense and in a societal sense. (MP)

  8. Energy Education in Elementary Science: Science Curriculum Improvement Study.

    ERIC Educational Resources Information Center

    Lind, Jackie; Premo, Joe

    This looseleaf teacher's manual is designed to facilitate using Science Curriculum Improvement Study (SCIS) for energy education in elementary schools. It is intended to be used with the SCIS Teacher's Guide as a supplement. The format of this manual matches a main SCIS concept with a closely related energy concept. Matrices show matched concepts…

  9. Energy Education in Elementary Science: Science Curriculum Improvement Study.

    ERIC Educational Resources Information Center

    Lind, Jackie; Premo, Joe

    This looseleaf teacher's manual is designed to facilitate using Science Curriculum Improvement Study (SCIS) for energy education in elementary schools. It is intended to be used with the SCIS Teacher's Guide as a supplement. The format of this manual matches a main SCIS concept with a closely related energy concept. Matrices show matched concepts…

  10. Teaching Basic Classification through an Elementary Science Unit on Food.

    ERIC Educational Resources Information Center

    Schubert, Nancy A.

    Five lesson plans are included in this unit designed to teach basic classification skills through the study of food. Each lesson plan contains an objective, list of materials needed, statement of the lesson problem, instructional strategies, learning outcomes, and evaluation method(s). Objectives of the lessons include: (1) grouping common animals…

  11. The Integration of Nutrition Education in the Basic Biomedical Sciences

    ERIC Educational Resources Information Center

    Raw, Isaias

    1977-01-01

    At the Center for Biomedical Education at the City University of New York, nutrition is integrated into the chemistry-biochemistry sequence of a six-year B.S.-M.D. program. Students perform an actual analysis of a sample of their own food, learning basic techniques and concepts, and also carry on experiments with rats on other diets. (Editor/LBH)

  12. Teaching Basic Classification through an Elementary Science Unit on Food.

    ERIC Educational Resources Information Center

    Schubert, Nancy A.

    Five lesson plans are included in this unit designed to teach basic classification skills through the study of food. Each lesson plan contains an objective, list of materials needed, statement of the lesson problem, instructional strategies, learning outcomes, and evaluation method(s). Objectives of the lessons include: (1) grouping common animals…

  13. The Integration of Nutrition Education in the Basic Biomedical Sciences

    ERIC Educational Resources Information Center

    Raw, Isaias

    1977-01-01

    At the Center for Biomedical Education at the City University of New York, nutrition is integrated into the chemistry-biochemistry sequence of a six-year B.S.-M.D. program. Students perform an actual analysis of a sample of their own food, learning basic techniques and concepts, and also carry on experiments with rats on other diets. (Editor/LBH)

  14. Solar energy education. Renewable energy activities for general science

    SciTech Connect

    Not Available

    1985-01-01

    Renewable energy topics are integrated with the study of general science. The literature is provided in the form of a teaching manual and includes such topics as passive solar homes, siting a home for solar energy, and wind power for the home. Other energy topics are explored through library research activities. (BCS)

  15. Physician perceptions of the role and value of basic science knowledge in daily clinical practice.

    PubMed

    Fischer, Jennifer A; Muller-Weeks, Susan

    2012-01-01

    The role of basic science education in a clinical setting remains unclear. Research to understand how academic clinicians perceive and use this part of their education can aid curricular development. To assess physician's attitudes toward the value of science knowledge in their clinical practice. Academic physicians from three medical schools completed a questionnaire about the utility of basic science education in core clinical tasks and in practice-based learning and improvement. A total of 109 clinical faculty returned the survey. Overall, 89% of the respondents indicated that basic science education is valuable to their clinical practice. When asked about the utility of basic science information in relation to direct patient care, greater than 50% of the doctors felt they use this when diagnosing and communicating with patients. This rose to greater than 60% when asked about choosing treatment options for their patients. Individuals also responded that basic science knowledge is valuable when developing evidence-based best practices. Specifically, 89% felt that they draw upon this information when training students/residents and 84% use this information when reading journal articles. This study shows that basic science education is perceived by responding academic physicians to be important to their clinical work.

  16. Solar Energy Project, Activities: Earth Science.

    ERIC Educational Resources Information Center

    Tullock, Bruce, Ed.; And Others

    This guide contains lesson plans and outlines of science activities which present concepts of solar energy in the context of earth science experiments. Each unit presents an introduction; objectives; skills and knowledge needed; materials; method; questions; recommendations for further study; and a teacher information sheet. The teacher…

  17. Solar Energy Project, Activities: Junior High Science.

    ERIC Educational Resources Information Center

    Tullock, Bruce, Ed.; And Others

    This guide contains lesson plans and outlines of science activities which present concepts of solar energy in the context of the junior high science curriculum. Each unit presents an introduction; objectives; skills and knowledge needed; materials; methods; questions; recommendations for further work; and a teacher information sheet. The teacher…

  18. Using Soils to Teach Basic Concepts in Science and Art

    NASA Astrophysics Data System (ADS)

    Lindbo, David L.; Kozlowski, Deborah; Robinson, Clay; Chapman, Susan

    2014-05-01

    Teaching primary and secondary school students (K-12) about science and art, although absolutely critical, can be difficult. Teachers have specific standards or subject matters that they are required to cover and often soils and soil science is not included in that list. We have struggled with ways to bring soil science information to the larger audience as the direct approach meets with resistance due to the time commitments to other standards. Our approach now is to use soils as a media or vehicle to teach key concepts in broad subject areas. We have developed several lesson plans in science, geography, math and art that focus on a concept but use soils to convey it. For example students make "mini" monoliths of a state soil. During this exercise students need to use skills in geography to find where their state soil occurs in their state and in the country. They need to understand colors in order to choose the correct colors to use to make their monolith. Finally, they must understand how scales work in order to make the monolith accurate in terms of horizon depths. Throughout the exercise discussion on my certain colors occur in the soil can be discussed. This discussion can lead to a qualitative understanding of chemistry and biology. This presentation will demonstrate this lesson and several others that have been developed and available through the Soil Science Society of America's K12 Education Committee.

  19. Nursing science: basic, applied, or practical? Implications for the art of nursing.

    PubMed

    Johnson, J L

    1991-09-01

    Nursing has long been described as both a science and an art. If the science of nursing is to be relevant to the art of nursing, then it must be conceptualized and pursued such that these two central components of nursing remain connected. Current conceptualizations of nursing science are examined in terms of the consequences that each conceptualization might have for the art of nursing. Pursuing nursing science as a basic science or an applied science disarticulates the science of nursing and the art of nursing. The author concludes that only if nursing science is conceptualized and pursued as a practical science will the science of nursing be consistently relevant to the art of nursing.

  20. Funding the Foundation: Basic Science at the Crossroads

    ERIC Educational Resources Information Center

    Hughes, Kent, Ed.; Sha, Lynn, Ed.

    2006-01-01

    These proceedings from a conference with leading experts examines the hugely successful American model of technological and scientific innovation. They stress the critical importance of government funding of physical science for the realms of national security, education, and industry. Kent Hughes and Frederick M. Bush, both of the Woodrow Wilson…

  1. CRC Tissue Core Management System (TCMS): Integration of Basic Science and Clinical Data for Translational Research

    PubMed Central

    Greaves, Andrew W.; Payne, Philip R.O.; Rassenti, Laura; Kipps, Thomas J.

    2003-01-01

    The Chronic Lymphocytic Leukemia (CLL) Research Consortium (CRC) consists of 9 geographically distributed sites conducting a program of research including both basic science and clinical components. The CRC TCMS was designed to capture and integrate basic science and clinical data sets. The system utilizes multiple data modeling methodologies and web-application platforms, and was designed with the high level objectives of providing an extensible, generalizable model for integrating data as required to conduct translational research. PMID:14728358

  2. Retention of basic science knowledge: a comparison between body system-based and clinical presentation curricula.

    PubMed

    Woloschuk, Wayne; Mandin, Henry; Harasym, Peter; Lorscheider, Fritz; Brant, Rollin

    2004-01-01

    When the University of Calgary implemented the clinical presentation (CP) curriculum in 1994, it was prospectively decided to administer the National Board of Medical Examiner's Comprehensive Basic Science Exam (CBSE) as a measure of students' basic science knowledge retention. The exam performance from 2 classes (1995, 1996) of the previous system-based (SB) curriculum was compared to exam performance of 2 classes (2000, 2002) of the CP curriculum. Data analyses employed 2 statistical models (covariate multiple linear regression and hierarchical mixed effects), and effect sizes were computed. Differences between CBSE mean scores produced by students from the SB and CP curricula showed a curricular effect on students' retention of basic science knowledge. However, preexisting differences between groups were found to be in the small-to-medium range. Evidence supporting the potential of schemes within a CP curriculum and their relation to basic science knowledge retention was observed. Effect size for the CP curriculum on students' retention of basic science knowledge was substantial; however, a notable part of that difference can be accounted for by extraneous and confounding factors. Further research utilizing more rigorous designs to investigate the relation between schemes and basic science retention is warranted.

  3. Atmospheric science: Energy and precipitation

    NASA Astrophysics Data System (ADS)

    Donohoe, Aaron

    2016-12-01

    The latitude of the tropical rainbelt is constrained by the energy balance between hemispheres. An expansion of this theory that includes longitudinal variations of atmospheric heating can predict regional changes in tropical precipitation.

  4. Accelerator Science: Luminosity vs. Energy

    SciTech Connect

    Lincoln, Don

    2016-09-19

    In the world of high energy physics there are several parameters that are important when one constructs a particle accelerator. Two crucial ones are the energy of the beam and the luminosity, which is another word for the number of particles in the beam. In this video, Fermilab’s Dr. Don Lincoln explains the differences and the pros and cons. He even works in an unexpected sporting event.

  5. Accelerator Science: Luminosity vs. Energy

    ScienceCinema

    Lincoln, Don

    2016-09-28

    In the world of high energy physics there are several parameters that are important when one constructs a particle accelerator. Two crucial ones are the energy of the beam and the luminosity, which is another word for the number of particles in the beam. In this video, Fermilab’s Dr. Don Lincoln explains the differences and the pros and cons. He even works in an unexpected sporting event.

  6. Why our patients (and we) need basic science research

    PubMed Central

    2013-01-01

    In times of fiscal austerity, the tendency is to seek instant, inexpensive gratification. In the case of biomedical research, this means the shortest path to practical clinical implementation. But fueling the translational pipeline with discovery depends critically on allowing the biomedical research community to follow their science where it takes them. Fiscal constraints carry with them the risk of squelching creativity and forfeiting the power of serendipity to provide the substrate for the translational engine in the future. PMID:23713087

  7. Why our patients (and we) need basic science research.

    PubMed

    Schor, Nina F

    2013-05-28

    In times of fiscal austerity, the tendency is to seek instant, inexpensive gratification. In the case of biomedical research, this means the shortest path to practical clinical implementation. But fueling the translational pipeline with discovery depends critically on allowing the biomedical research community to follow their science where it takes them. Fiscal constraints carry with them the risk of squelching creativity and forfeiting the power of serendipity to provide the substrate for the translational engine in the future.

  8. The Museum of Science and Industry Basic List of Children's Science Books 1973-1984.

    ERIC Educational Resources Information Center

    Richter, Bernice; Wenzel, Duane

    Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; encyclopedias and reference books; environment and conservation; fiction; general science; life sciences; marine life; mathematics and computer science; medical and health sciences; physics and chemistry; plant…

  9. The Museum of Science and Industry Basic List of Children's Science Books 1973-1984.

    ERIC Educational Resources Information Center

    Richter, Bernice; Wenzel, Duane

    Children's science books are listed under these headings: animals; astronomy; aviation and space; biography; careers; earth sciences; encyclopedias and reference books; environment and conservation; fiction; general science; life sciences; marine life; mathematics and computer science; medical and health sciences; physics and chemistry; plant…

  10. 78 FR 15937 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Fusion Energy Sciences Advisory Committee..., Designated Federal Officer, Office of Fusion Energy Sciences; U.S. Department of Energy; 1000 Independence...

  11. 77 FR 485 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Fusion Energy Sciences Advisory Committee.... Synakowski, Designated Federal Officer, Office of Fusion Energy Sciences; U.S. Department of Energy; 1000...

  12. Cause and Effect: Testing a Mechanism and Method for the Cognitive Integration of Basic Science.

    PubMed

    Kulasegaram, Kulamakan; Manzone, Julian C; Ku, Cheryl; Skye, Aimee; Wadey, Veronica; Woods, Nicole N

    2015-11-01

    Methods of integrating basic science with clinical knowledge are still debated in medical training. One possibility is increasing the spatial and temporal proximity of clinical content to basic science. An alternative model argues that teaching must purposefully expose relationships between the domains. The authors compared different methods of integrating basic science: causal explanations linking basic science to clinical features, presenting both domains separately but in proximity, and simply presenting clinical features First-year undergraduate health professions students were randomized to four conditions: (1) science-causal explanations (SC), (2) basic science before clinical concepts (BC), (3) clinical concepts before basic science (CB), and (4) clinical features list only (FL). Based on assigned conditions, participants were given explanations for four disorders in neurology or rheumatology followed by a memory quiz and diagnostic test consisting of 12 cases which were repeated after one week. Ninety-four participants completed the study. No difference was found on memory test performance, but on the diagnostic test, a condition by time interaction was found (F[3,88] = 3.05, P < .03, ηp = 0.10). Although all groups had similar immediate performance, the SC group had a minimal decrease in performance on delayed testing; the CB and FL groups had the greatest decreases. These results suggest that creating proximity between basic science and clinical concepts may not guarantee cognitive integration. Although cause-and-effect explanations may not be possible for all domains, making explicit and specific connections between domains will likely facilitate the benefits of integration for learners.

  13. Development and Validation of a Project Package for Junior Secondary School Basic Science

    ERIC Educational Resources Information Center

    Udofia, Nsikak-Abasi

    2014-01-01

    This was a Research and Developmental study designed to develop and validate projects for Junior Secondary School Basic Science instruction and evaluation. The projects were developed using the project blueprint and sent for validation by experts in science education and measurement and evaluation; using a project validation scale. They were to…

  14. Selecting Students for Medical School: What Predicts Success during Basic Science Studies? A Cognitive Approach.

    ERIC Educational Resources Information Center

    Lindblom-Ylanne, Sari; And Others

    1996-01-01

    A study with 503 applicants to the University of Helsinki (Finland) medical school compared the predictive validity of multiple-choice science tests and a "learning-from-text" test (LFT) designed to measure deep-level text processing. Results indicated the LFT was the best predictor of student academic progress in basic science courses.…

  15. Science and Nonscience Students' Ideas about Basic Astronomy Concepts in Preservice Training for Elementary School Teachers

    ERIC Educational Resources Information Center

    Kalkan, Huseyin; Kiroglu, Kasim

    2007-01-01

    A 14-item questionnaire was given to 100 students in preservice training to become primary and secondary education faculty. Results showed that science and non-science majors held a series of misconceptions about several basic topics central to astronomy. The changes in astronomy misconceptions were analyzed by means of a written questionnaire…

  16. Proceedings of the seventeenth symposium on energy engineering sciences

    SciTech Connect

    1999-05-13

    This Proceedings Volume includes the technical papers that were presented during the Seventeenth Symposium on Energy Engineering Sciences on May 13-14, 1999, at Argonne National Laboratory, Argonne, Illinois. The Symposium was structured into seven technical sessions, which included 25 individual presentations followed by discussion and interaction with the audience. A list of participants is appended to this volume. The DOE Office of Basic Energy Sciences (BES), of which Engineering Research is a component program, is responsible for the long-term, mission-oriented research in the Department. The Office has prime responsibility for establishing the basic scientific foundation upon which the Nation's future energy options will be identified, developed, and built. BES is committed to the generation of new knowledge necessary to solve present and future problems regarding energy exploration, production, conversion, and utilization, while maintaining respect for the environment. Consistent with DOE/BES mission, the Engineering Research Program is charged with the identification, initiation, and management of fundamental research on broad, generic topics addressing energy-related engineering problems. Its stated goals are to improve and extend the body of knowledge underlying current engineering practice so as to create new options for enhancing energy savings and production, prolonging the useful life of energy-related structures and equipment, and developing advanced manufacturing technologies and materials processing. The program emphasis is on reducing costs through improved industrial production and performance and expanding the nation's store of fundamental knowledge for solving anticipated and unforeseen engineering problems in energy technologies. To achieve these goals, the Engineering Research Program supports approximately 130 research projects covering a broad spectrum of topics that cut across traditional engineering disciplines. The program focuses on

  17. Pharmacotherapy of cardiac arrhythmias--basic science for clinicians.

    PubMed

    Shu, Juan; Zhou, Jun; Patel, Chinmay; Yan, Gan-Xin

    2009-11-01

    Cardiac arrhythmias occur in approximately 5.3% of the population and contribute substantially to morbidity and mortality. Pharmacological therapy still remains the major approach in management of patients with nearly every form of cardiac arrhythmia. Effective and safe management of cardiac arrhythmias with antiarrhythmic drugs requires understanding of basic mechanisms for various cardiac arrhythmias, clinical diagnosis of an arrhythmia and identification of underlying cardiac diseases, pharmacokinetics, and antiarrhythmic properties of each individual antiarrhythmic drug. Most cardiac arrhythmias occur via one of the two mechanisms: abnormal impulse formation and reentry or both. Antiarrhythmic drugs primarily work via influencing cardiac automaticity or triggered activity or by their effects on effective refractoriness of cardiac cells. Proarrhythmic effects of antiarrhythmic drugs are also briefly discussed in this review article.

  18. A Sustainable Energy Laboratory Course for Non-Science Majors

    NASA Astrophysics Data System (ADS)

    Nathan, Stephen A.; Loxsom, Fred

    2016-10-01

    Sustainable energy is growing in importance as the public becomes more aware of climate change and the need to satisfy our society's energy demands while minimizing environmental impacts. To further this awareness and to better prepare a workforce for "green careers," we developed a sustainable energy laboratory course that is suitable for high school and undergraduate students, especially non-science majors. Thirteen hands-on exercises provide an overview of sustainable energy by demonstrating the basic principles of wind power, photovoltaics, electric cars, lighting, heating/cooling, insulation, electric circuits, and solar collectors. The order of content presentation and instructional level (secondary education or college) can easily be modified to suit instructor needs and/or academic programs (e.g., engineering, physics, renewable and/or sustainable energy).

  19. Energy Storage. Teachers Guide. Science Activities in Energy.

    ERIC Educational Resources Information Center

    Jacobs, Mary Lynn, Ed.

    Included in this science activities energy package for students in grades 4-10 are 12 activities related to energy storage. Each activity is outlined on the front and back of a single sheet and is introduced by a key question. Most of the activities can be completed in the classroom with materials readily available in any community. Among the…

  20. Complex biomedical systems: from basic science to translation.

    PubMed

    Grzywacz, Norberto M

    2012-07-01

    The Department of Biomedical Engineering (BME) of the University of Southern California (BME@USC) has a longstanding tradition of advancing biomedicine through the development and application of novel engineering ideas. More than 80 primary and affiliated faculty members conduct cutting-edge research in a wide variety of areas, such as neuroengineering, biosystems and biosignal analysis, medical devices (including biomicroelectromechanical systems (bioMEMS) and bionanotechnology), biomechanics, bioimaging, and imaging informatics. Currently, the department hosts six internationally recognized research centers: the Biomimetic MicroElectronic Systems Engineering Research Center (funded by the National Science Foundation), the Biomedical Simulations Resource [funded by the National Institutes of Health (NIH)], the Medical Ultrasonic Transducer Center (funded by NIH), the Center for Neural Engineering, the Center for Vision Science and Technology (funded by an NIH Bioengineering Research Partnership Grant), and the Center for Genomic and Phenomic Studies in Autism (funded by NIH). BME@USC ranks in the top tier of all U.S. BME departments in terms of research funding per faculty.

  1. Proceedings of the fifteenth symposium on energy engineering sciences

    SciTech Connect

    1997-11-01

    This Proceedings Volume includes the technical papers that were presented during the Fifteenth Symposium on Energy Engineering Sciences on May 14-15, 1997, at Argonne National Laboratory, Argonne, Illinois. The Symposium was organized into eight technical sessions, which included 32 individual presentations followed by discussion and interaction with the audience. The topics of the eight sessions are: multiphase flows 1; multiphase flows 2; mostly optics; fluid mechanics; nonlinear fields; welding and cracks; materials; and controls. The DOE Office of Basic Energy Sciences, of which Engineering Research is a component program, is responsible for the long-term mission-oriented research in the Department. It has the prime responsibility for establishing the basic scientific foundation upon which the Nation`s future energy options will have to be identified, developed, and built. It is committed to the generation of new knowledge necessary for the solution of present and future problems of energy exploration, production, conversion, and utilization, consistent with respect for the environment. Separate abstracts have been indexed into the energy database for contributions to this Symposium.

  2. Is basic science disappearing from medicine? The decline of biomedical research in the medical literature.

    PubMed

    Steinberg, Benjamin E; Goldenberg, Neil M; Fairn, Gregory D; Kuebler, Wolfgang M; Slutsky, Arthur S; Lee, Warren L

    2016-02-01

    Explosive growth in our understanding of genomics and molecular biology have fueled calls for the pursuit of personalized medicine, the notion of harnessing biologic variability to provide patient-specific care. This vision will necessitate a deep understanding of the underlying pathophysiology in each patient. Medical journals play a pivotal role in the education of trainees and clinicians, yet we suspected that the amount of basic science in the top medical journals has been in decline. We conducted an automated search strategy in PubMed to identify basic science articles and calculated the proportion of articles dealing with basic science in the highest impact journals for 8 different medical specialties from 1994 to 2013. We observed a steep decline (40-60%) in such articles over time in almost all of the journals examined. This rapid decline in basic science from medical journals is likely to affect practitioners' understanding of and interest in the basic mechanisms of disease and therapy. In this Life Sciences Forum, we discuss why this decline may be occurring and what it means for the future of science and medicine.

  3. The Path to Sustainable Nuclear Energy. Basic and Applied Research Opportunities for Advanced Fuel Cycles

    SciTech Connect

    Finck, P.; Edelstein, N.; Allen, T.; Burns, C.; Chadwick, M.; Corradini, M.; Dixon, D.; Goff, M.; Laidler, J.; McCarthy, K.; Moyer, B.; Nash, K.; Navrotsky, A.; Oblozinsky, P.; Pasamehmetoglu, K.; Peterson, P.; Sackett, J.; Sickafus, K. E.; Tulenko, J.; Weber, W.; Morss, L.; Henry, G.

    2005-09-01

    The objective of this report is to identify new basic science that will be the foundation for advances in nuclear fuel-cycle technology in the near term, and for changing the nature of fuel cycles and of the nuclear energy industry in the long term. The goals are to enhance the development of nuclear energy, to maximize energy production in nuclear reactor parks, and to minimize radioactive wastes, other environmental impacts, and proliferation risks. The limitations of the once-through fuel cycle can be overcome by adopting a closed fuel cycle, in which the irradiated fuel is reprocessed and its components are separated into streams that are recycled into a reactor or disposed of in appropriate waste forms. The recycled fuel is irradiated in a reactor, where certain constituents are partially transmuted into heavier isotopes via neutron capture or into lighter isotopes via fission. Fast reactors are required to complete the transmutation of long-lived isotopes. Closed fuel cycles are encompassed by the Department of Energy?s Advanced Fuel Cycle Initiative (AFCI), to which basic scientific research can contribute. Two nuclear reactor system architectures can meet the AFCI objectives: a ?single-tier? system or a ?dual-tier? system. Both begin with light water reactors and incorporate fast reactors. The ?dual-tier? systems transmute some plutonium and neptunium in light water reactors and all remaining transuranic elements (TRUs) in a closed-cycle fast reactor. Basic science initiatives are needed in two broad areas: ? Near-term impacts that can enhance the development of either ?single-tier? or ?dual-tier? AFCI systems, primarily within the next 20 years, through basic research. Examples: Dissolution of spent fuel, separations of elements for TRU recycling and transmutation Design, synthesis, and testing of inert matrix nuclear fuels and non-oxide fuels Invention and development of accurate on-line monitoring systems for chemical and nuclear species in the nuclear

  4. Cosmic Visions Dark Energy: Science

    SciTech Connect

    Dodelson, S.; Slosar, A.; Heitmann, K.; Hirata, C.; Honscheid, K.; Roodman, A.; Seljak, U.; Trodden, M.

    2016-04-26

    Cosmic surveys provide crucial information about high energy physics including strong evidence for dark energy, dark matter, and inflation. Ongoing and upcoming surveys will start to identify the underlying physics of these new phenomena, including tight constraints on the equation of state of dark energy, the viability of modified gravity, the existence of extra light species, the masses of the neutrinos, and the potential of the field that drove inflation. Even after the Stage IV experiments, DESI and LSST, complete their surveys, there will still be much information left in the sky. This additional information will enable us to understand the physics underlying the dark universe at an even deeper level and, in case Stage IV surveys find hints for physics beyond the current Standard Model of Cosmology, to revolutionize our current view of the universe. There are many ideas for how best to supplement and aid DESI and LSST in order to access some of this remaining information and how surveys beyond Stage IV can fully exploit this regime. These ideas flow to potential projects that could start construction in the 2020's.

  5. Cosmic Visions Dark Energy. Science

    SciTech Connect

    Dodelson, Scott; Heitmann, Katrin; Hirata, Chris; Honscheid, Klaus; Roodman, Aaron; Seljak, Uroš; Slosar, Anže; Trodden, Mark

    2016-04-26

    Cosmic surveys provide crucial information about high energy physics including strong evidence for dark energy, dark matter, and inflation. Ongoing and upcoming surveys will start to identify the underlying physics of these new phenomena, including tight constraints on the equation of state of dark energy, the viability of modified gravity, the existence of extra light species, the masses of the neutrinos, and the potential of the field that drove inflation. Even after the Stage IV experiments, DESI and LSST, complete their surveys, there will still be much information left in the sky. This additional information will enable us to understand the physics underlying the dark universe at an even deeper level and, in case Stage IV surveys find hints for physics beyond the current Standard Model of Cosmology, to revolutionize our current view of the universe. There are many ideas for how best to supplement and aid DESI and LSST in order to access some of this remaining information and how surveys beyond Stage IV can fully exploit this regime. These ideas flow to potential projects that could start construction in the 2020's.

  6. Trends in Basic Sciences Education in Dental Schools, 1999-2016.

    PubMed

    Lantz, Marilyn S; Shuler, Charles F

    2017-08-01

    The purpose of this study was to examine data published over the past two decades to identify trends in the basic sciences curriculum in dental education, provide an analysis of those trends, and compare them with trends in the basic sciences curriculum in medical education. Data published from the American Dental Association (ADA) Surveys of Dental Education, American Dental Education Association (ADEA) Surveys of Dental School Seniors, and two additional surveys were examined. In large part, survey data collected focused on the structure, content, and instructional strategies used in dental education: what was taught and how. Great variability was noted in the total clock hours of instruction and the clock hours of basic sciences instruction reported by dental schools. Moreover, the participation of medical schools in the basic sciences education of dental students appears to have decreased dramatically over the past decade. Although modest progress has been made in implementing some of the curriculum changes recommended in the 1995 Institute of Medicine report such as integrated basic and clinical sciences curricula, adoption of active learning methods, and closer engagement with medical and other health professions education programs, educational effectiveness studies needed to generate data to support evidence-based approaches to curriculum reform are lacking. Overall, trends in the basic sciences curriculum in medical education were similar to those for dental education. Potential drivers of curriculum change were identified, as was recent work in other fields that should encourage reconsideration of dentistry's approach to basic sciences education. This article was written as part of the project "Advancing Dental Education in the 21st Century."

  7. Japanese representation in leading general medicine and basic science journals: a comparison of two decades.

    PubMed

    Fukui, Tsuguya; Takahashi, Osamu; Rahman, Mahbubur

    2013-11-01

    During 1991-2000, Japan contribution to the top general medicine journals was very small although the contribution to the top basic science journals was sizeable. However, it has not been examined whether the contribution to the top general medicine and basic science journals has changed during the last decade (2001-2010). The objective of this study was to compare Japan representation in high-impact general medicine and basic science journals between the years 1991-2000 and 2001-2010. We used PubMed database to examine the frequency of articles originated from Japan and published in 7 high-impact general medicine and 6 high-impact basic science journals. Several Boolean operators were used to connect name of the journal, year of publication and corresponding authors' affiliation in Japan. Compared to the 1991-2000 decade, Japan contribution to the top general medicine journals did not increase over the 2001-2010 period (0.66% vs. 0.74%, P = 0.255). However, compared to the same period, its contribution to the top basic science journals increased during 2001-2010 (2.51% vs. 3.60%, P < 0.001). Japan representation in basic science journals showed an upward trend over the 1991-2000 period (P < 0.001) but remained flat during 2001-2010 (P = 0.177). In contrast, the trend of Japan representation in general medicine journals remained flat both during 1991-2000 (P = 0.273) and 2001-2010 (P = 0.073). Overall, Japan contribution to the top general medicine journals has remained small and unchanged over the last two decades. However, top basic science journals had higher Japan representation during 2001-2010 compared to 1991-2000.

  8. 76 FR 49757 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of... that the Fusion Energy Sciences Advisory Committee will be renewed for a two-year period beginning on...-range plans, priorities, and strategies for advancing plasma science, fusion science, and fusion...

  9. Sensory Gating: A Translational Effort From Basic to Clinical Science

    PubMed Central

    Cromwell, Howard C.; Mears, Ryan P.; Wan, Li; Boutros, Nash N.

    2014-01-01

    Sensory gating (SG) is a prevalent physiological process important for information filtering in complex systems. SG is evaluated by presenting repetitious stimuli and measuring the degree of neural inhibition that occurs. SG has been found to be impaired in several psychiatric disorders. Recent animal and human research has made great progress in the study of SG, and in this review we provide an overview of recent research on SG using different methods. Animal research has uncovered findings that suggest 1) SG is displayed by single neurons and can be similar to SG observed from scalp recordings in humans, 2) SG is found in numerous brain structures located in sensory, motor and limbic subregions, 3) SG can be significantly influenced by state changes of the organism, and 4) SG has a diverse pharmacological profile accented by a strong influence from nicotine receptor activation. Human research has addressed similar issues using deep electrode recordings of brain structures. These experiments have revealed that 1) SG can be found in cortical regions surrounding hippocampus, 2) the order of neural processing places hippocampal involvement during a later stage of sensory processing than originally thought, and 3) multiple subtypes of gating exist that could be dependent on different brain circuits and more or less influenced by alterations in organismal state. Animal and human research both have limitations. We emphasize the need for integrative approaches to understand the process and combine information between basic and clinical fields so that a more complete picture of SG will emerge. PMID:18450171

  10. Energy Frontier Research Centers: Science for Our Nation's Energy Future, September 2016

    SciTech Connect

    None, None

    2016-09-01

    As world demand for energy rapidly expands, transforming the way energy is collected, stored, and used has become a defining challenge of the 21st century. At its heart, this challenge is a scientific one, inspiring the U.S. Department of Energy’s (DOE) Office of Basic Energy Sciences (BES) to establish the Energy Frontier Research Center (EFRC) program in 2009. The EFRCs represent a unique approach, bringing together creative, multidisciplinary scientific teams to perform energy-relevant basic research with a complexity beyond the scope of single-investigator projects. These centers take full advantage of powerful new tools for characterizing, understanding, modeling, and manipulating matter from atomic to macroscopic length scales. They also train the next-generation scientific workforce by attracting talented students and postdoctoral researchers interested in energy science. The EFRCs have collectively demonstrated the potential to substantially advance the scientific understanding underpinning transformational energy technologies. Both a BES Committee of Visitors and a Secretary of Energy Advisory Board Task Force have found the EFRC program to be highly successful in meeting its goals. The scientific output from the EFRCs is impressive, and many centers have reported that their results are already impacting both technology research and industry. This report on the EFRC program includes selected highlights from the initial 46 EFRCs and the current 36 EFRCs.

  11. 75 FR 8685 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Fusion Energy Sciences Advisory Committee... Sciences; U.S. Department of Energy; 1000 Independence Avenue, SW.; Washington, DC 20585-1290; Telephone...

  12. What's hot, what's new at WTC--basic science.

    PubMed

    Bromberg, J S

    2015-02-01

    The World Transplant Congress of 2014 presented a broad swath of science that touched on many disparate aspects of cell and organ transplantation, molecular and cellular immunology, systems biology, development, technology and translation into humans. A number of themes emerged this year. B cell biology and antibody chemistry were prominent, as they have been for several years. T cells, co-stimulatory blockade and regulatory T cells continue to dominate many aspects of immune research. Many new aspects of monocyte, macrophage, NK cell and NK T cell development, biology and regulation are now being explored. Diverse aspects of organ injury and the acute and chronic responses to injury are being investigated with new techniques, new targets and a resurgent vigor. Novel advances in xenotransplantation and experimental tolerance garnered much attention. Newer investigations in microbiota and nanotechnology promise significant gains in the near future. Lastly the 'omics of DNA, RNA, proteins, metabolites, bacteria and enzyme actions promise new understanding in biological systems and how to control those systems. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

  13. Fusion energy science: Clean, safe, and abundant energy through innovative science and technology

    SciTech Connect

    2001-01-01

    Fusion energy science combines the study of the behavior of plasmas--the state of matter that forms 99% of the visible universe--with a vision of using fusion--the energy source of the stars--to create an affordable, plentiful, and environmentally benign energy source for humankind. The dual nature of fusion energy science provides an unfolding panorama of exciting intellectual challenge and a promise of an attractive energy source for generations to come. The goal of this report is a comprehensive understanding of plasma behavior leading to an affordable and attractive fusion energy source.

  14. Cognition before curriculum: rethinking the integration of basic science and clinical learning.

    PubMed

    Kulasegaram, Kulamakan Mahan; Martimianakis, Maria Athina; Mylopoulos, Maria; Whitehead, Cynthia R; Woods, Nicole N

    2013-10-01

    Integrating basic science and clinical concepts in the undergraduate medical curriculum is an important challenge for medical education. The health professions education literature includes a variety of educational strategies for integrating basic science and clinical concepts at multiple levels of the curriculum. To date, assessment of this literature has been limited. In this critical narrative review, the authors analyzed literature published in the last 30 years (1982-2012) using a previously published integration framework. They included studies that documented approaches to integration at the level of programs, courses, or teaching sessions and that aimed to improve learning outcomes. The authors evaluated these studies for evidence of successful integration and to identify factors that contribute to integration. Several strategies at the program and course level are well described but poorly evaluated. Multiple factors contribute to successful learning, so identifying how interventions at these levels result in successful integration is difficult. Evidence from session-level interventions and experimental studies suggests that integration can be achieved if learning interventions attempt to link basic and clinical science in a causal relationship. These interventions attend to how learners connect different domains of knowledge and suggest that successful integration requires learners to build cognitive associations between basic and clinical science. One way of understanding the integration of basic and clinical science is as a cognitive activity occurring within learners. This perspective suggests that learner-centered, content-focused, and session-level-oriented strategies can achieve cognitive integration.

  15. [A new, problem oriented medicine curriculum in Utrecht: less basic science knowledge].

    PubMed

    Keijsers, Carolina J P W; Custers, Eugène J F M; ten Cate, Olle Th J

    2009-01-01

    To investigate whether the transition from a conventional, discipline-based curriculum to a problem-orientated, integrated curriculum at the University Medical Center Utrecht, the Netherlands, has resulted in students having less knowledge of the basic medical sciences. Comparative. The difference in the amount of basic science between the curricula was quantitatively assessed. 37 final-year students in each curriculum volunteered to complete a test specifically designed to measure knowledge of the basic sciences, a few weeks before their graduation. The transition from the old to the new curriculum resulted in a decline of almost half in the amount of time dedicated to the basic sciences, from 84 to 48 'fulltime week equivalents'. Students in the old curriculum performed significantly better on the test than students in the new curriculum, with 43.2% (SD: 9.56) correct answers versus 35.8% (SD: 8.19) correct answers respectively, which amounted to an effect size of 0.828 (Cohen-d). Yet, on the pathophysiology/pathology subscale, students in each curriculum showed similar performance: 36.1% (SD: 11.55) correct answers for students in the old curriculum, versus 37.2% (SD: 11.66) correct answers for students in the new curriculum. Students in the old curriculum had overall significantly more knowledge of the basic sciences than students in the new curriculum, except for pathophysiology/pathology, though the time devoted to this discipline in the new curriculum had also decreased considerably.

  16. Energy Frontier Research Center, Center for Materials Science of Nuclear Fuels

    SciTech Connect

    Todd R. Allen

    2011-12-01

    This is a document required by Basic Energy Sciences as part of a mid-term review, in the third year of the five-year award period and is intended to provide a critical assessment of the Center for Materials Science of Nuclear Fuels (strategic vision, scientific plans and progress, and technical accomplishments).

  17. Energy Conservation in the Home. A Basic Teaching Unit on Energy. Revised.

    ERIC Educational Resources Information Center

    McDermott, Hugh, Ed.; Scharmann, Larry, Ed.

    Recommended for grades 7-9 science and/or social studies classes, this 8-10 day unit provides students with experiences in conserving energy through small conservation activities and practices. The unit consists of 11 activities with rationale, objectives, and instructional strategies provided for each activity. Students are given information on…

  18. Energy from the Atom. A Basic Teaching Unit on Energy. Revised.

    ERIC Educational Resources Information Center

    McDermott, Hugh, Ed.; Scharmann, Larry, Ed.

    Recommended for grades 9-12 social studies and/or physical science classes, this 4-8 day unit focuses on four topics: (1) the background and history of atomic development; (2) two common types of nuclear reactors (boiling water and pressurized water reactors); (3) disposal of radioactive waste; and (4) the future of nuclear energy. Each topic…

  19. Energy from the Atom. A Basic Teaching Unit on Energy. Revised.

    ERIC Educational Resources Information Center

    McDermott, Hugh, Ed.; Scharmann, Larry, Ed.

    Recommended for grades 9-12 social studies and/or physical science classes, this 4-8 day unit focuses on four topics: (1) the background and history of atomic development; (2) two common types of nuclear reactors (boiling water and pressurized water reactors); (3) disposal of radioactive waste; and (4) the future of nuclear energy. Each topic…

  20. Sex bias exists in basic science and translational surgical research.

    PubMed

    Yoon, Dustin Y; Mansukhani, Neel A; Stubbs, Vanessa C; Helenowski, Irene B; Woodruff, Teresa K; Kibbe, Melina R

    2014-09-01

    Although the Revitalization Act was passed in 1993 to increase enrollment of women in clinical trials, there has been little focus on sex disparity in basic and translational research. We hypothesize that sex bias exists in surgical biomedical research. Manuscripts from Annals of Surgery, American Journal of Surgery, JAMA Surgery, Journal of Surgical Research, and Surgery from 2011 to 2012 were reviewed. Data abstracted included study type, sex of the animal or cell studied, location, and presence of sex-based reporting of data. Of 2,347 articles reviewed, 618 included animals and/or cells. For animal research, 22% of the publications did not specify the sex of the animals. Of the reports that did specify the sex, 80% of publications included only males, 17% only females, and 3% both sexes. A greater disparity existed in the number of animals studied: 16,152 (84%) male and 3,173 (16%) female (P < .0001). For cell research, 76% of the publications did not specify the sex. Of the papers that did specify the sex, 71% of publications included only males, 21% only females, and 7% both sexes. Only 7 (1%) studies reported sex-based results. For publications on female-prevalent diseases, 44% did not report the sex studied. Of those reports that specified the sex, only 12% studied female animals. More international than national (ie, United States) publications studied only males (85% vs 71%, P = .004), whereas more national publications did not specify the sex (47% vs 20%, P < .0001). A subanalysis of a single journal showed that across three decades, the number of male-only studies and usage of male animals has become more disparate over time. Sex bias, be it overt, inadvertent, situational, financial, or ignorant, exists in surgical biomedical research. Because biomedical research serves as the foundation for subsequent clinical research and medical decision-making, it is imperative that this disparity be addressed because conclusions derived from such studies may

  1. The Year in Basic Science: calmodulin kinase cascades.

    PubMed

    Means, Anthony R

    2008-12-01

    This article highlights studies published during the past year that represent significant scientific achievements in the world of calmodulin kinase cascades. Calmodulin is the primary receptor for calcium present in all cells. The binding of its calcium ligand results in a conformational change in calmodulin, which allows the calcium-calmodulin complex to interact with many different targets. In the studies to be summarized in this review, the particular calmodulin cascade involved is shown to be the pathway responsible for important biological responses, including long-term memory formation, dendritic cell survival, hypercapnia, neuronal migration, synapse formation, autophagy, fatty acid oxidation, and energy balance. In some cases, the pathway was previously unknown, and the identification of the calmodulin cascade represents the definition of roles. In other cases, manipulating the cascade has suggested therapeutic approaches to certain diseases, most significantly, type 2 diabetes and obesity.

  2. Wind Energy Workforce Development: Engineering, Science, & Technology

    SciTech Connect

    Lesieutre, George A.; Stewart, Susan W.; Bridgen, Marc

    2013-03-29

    Broadly, this project involved the development and delivery of a new curriculum in wind energy engineering at the Pennsylvania State University; this includes enhancement of the Renewable Energy program at the Pennsylvania College of Technology. The new curricula at Penn State includes addition of wind energy-focused material in more than five existing courses in aerospace engineering, mechanical engineering, engineering science and mechanics and energy engineering, as well as three new online graduate courses. The online graduate courses represent a stand-alone Graduate Certificate in Wind Energy, and provide the core of a Wind Energy Option in an online intercollege professional Masters degree in Renewable Energy and Sustainability Systems. The Pennsylvania College of Technology erected a 10 kilowatt Xzeres wind turbine that is dedicated to educating the renewable energy workforce. The entire construction process was incorporated into the Renewable Energy A.A.S. degree program, the Building Science and Sustainable Design B.S. program, and other construction-related coursework throughout the School of Construction and Design Technologies. Follow-on outcomes include additional non-credit opportunities as well as secondary school career readiness events, community outreach activities, and public awareness postings.

  3. The challenge for basic science education in problem-based medical curricula.

    PubMed

    Sweeney, G

    1999-02-01

    There has been intense debate about medical curriculum reform since the early 1950s. The last 25 years have seen a steady shift ward problem-based learning curriculum design in schools of medicine and allied health sciences. This trend has been less challenging for clinical departments than for departments of basic science, where it has often evoked anxiety, antipathy, lack of cooperation, and general mistrust. This appears paradoxical, as problem-based learning (PBL) is promoted as an improved method of integrating scientific concepts, and the advances that drive much of modern medical practice are advances in the basic sciences. While proponents of PBL argue that the approach promotes better integration and use of scientific concepts, the evidence, such as it is, is against this. As well, other evidence suggests that clinicians do not use basic science concepts extensively in their practice. This then questions the utility of scientific knowledge in a medical curriculum. This article examines this notion of utility (the quality or state of being useful), to establish some ground rules for what does, and does not, possess utility, and to present strategies to develop specific objectives from general statements concerning utility. Understanding of biologic and pathologic processes becomes of central importance and arguably possesses utility. If it is both required and evaluated, such understanding necessitates mastery of basic science concepts. Previously, the presentation of the basic sciences in medical curricula has emphasized the acquisition of knowledge rather than its use. Such learning has been perceived to lack utility; strategies to enhance the value of studying basic science concepts are suggested. If the importance of objectives in the basic medical sciences is accepted, these objectives should be achieved early in training, maintained at exit from medical school, and revisited in continuing medical education. The process of change in medical education

  4. Basic research needs and priorities in solar energy. Volume I. Executive summary. Technology crosscuts for DOE

    SciTech Connect

    Jayadev, T S; Roessner, D

    1980-01-01

    This report identifies, describes, and recommends priorities for basic research important to the future development of solar energy. In response to a request from the US Department of Energy, SERI surveyed more than 120 leading scientists who were engaged in or knowledgeable of solar-related research. SERI scientists relied heavily on the opinions of scientists polled, but weighted their own recommendations and opinions equally. The result is an amalgam of national scientific opinion representing the views of key researchers in relevant disciplines and of SERI staff members. The Scientific disciplines included in the report are: chemistry, biology, materials sciences, engineering and mathematics, and the social and behavioral sciences. Each discipline is subdivided into two to five topical areas and, wintin each topical area, research needs are described and ranked according to the priorities suggested in the survey. Three categories of priority were established: Crucial, important, and needed. A narrative accompanying the descripton of research needs in each topical area discusses the importance of research in the area for solar energy development and presents the bases for the priority rankings recommended.

  5. Systematic Approach to Remediation in Basic Science Knowledge for Preclinical Students: A case study

    NASA Astrophysics Data System (ADS)

    Amara, Francis

    Remediation of pre-clerkship students for deficits in basic science knowledge should help them overcome their learning deficiencies prior to clerkship. However, very little is known about remediation in basic science knowledge during pre-clerkship. This study utilized the program theory framework to collect and organize mixed methods data of the remediation plan for pre-clerkship students who failed their basic science cognitive examinations in a Canadian medical school. This plan was analyzed using a logic model narrative approach and compared to literature on the learning theories. The analysis showed a remediation plan that was strong on governance and verification of scores, but lacked: clarity and transparency of communication, qualified remedial tutors, individualized diagnosis of learner's deficits, and student centered learning. Participants admitted uncertainty about the efficacy of the remediation process. A remediation framework is proposed that includes student-centered participation, individualized learning plan and activities, deliberate practice, feedback, reflection, and rigorous reassessment.

  6. Predicting success of pharmacy students in basic science and clinical clerkship courses.

    PubMed

    Kimberlin, C L; Hadsall, R S; Gourley, D R; Benedict, L K

    1983-04-01

    A number of studies on the ability of admissions variables to predict success in pharmacy schools have examined only success in the first professional year, which typically consists primarily of basic science courses. This study examined not only grades in basic science courses but also performance on clinical clerkships, for two classes of students. It also examined the ability of various personality variables to predict performance in clinical and basic science coursework. Previous grade point average (GPA) was the best single predictor of performance. In one class, the personality variable of Responsibility best predicted clinical clerkship performance. However, it only accounted for 13 percent of the variance in clerkship grades. Pharmacy College Admission Test (PCAT) Biology and PCAT Verbal Ability scores added to the predictive ability of previous GPA in one class, but none of the PCAT scales entered a prediction equation for the other class. The limitations on our ability to predict, with any consistency, academic performance in pharmacy school is discussed.

  7. Basic Steps to Using the Energy Savings Plus Health Guidelines

    EPA Pesticide Factsheets

    he Energy Savings Plus Health Guide equips school districts to integrate indoor air quality protections into school energy efficiency retrofits and other building upgrade projects. This document describes steps to using the Energy Savings Plus Health guide

  8. Computational Support for Alternative Confinement Concepts Basic Plasma Science

    SciTech Connect

    Dalton D. Schnack

    2002-12-09

    This is the final report for contract DE-FG03-99ER54528, ''Computational Support for Alternative Confinement Concepts''. Progress was made in the following areas of investigation: (1) Extensive studies of the confinement properties of conventional Reversed-field Pinch (RFP) configurations (i.e., without current profile control) were performed in collaboration with the Royal Institute of Technology (KTH) in Stockholm, Sweden. These studies were carried out using the full 3-dimensional, finite-{beta}, resistive MHD model in the DEBS code, including ohmic heating and anisotropic heat conduction, and thus for the first time included the self-consistent effects of the dynamo magnetic fluctuations on the confinement properties of the RFP. By using multi-variant regression analysis of these results, scaling laws for various properties characterizing the conventional RFP were obtained. In particular, it was found that the, for constant ratio of I/N (where I is the current and N = na{sup 2} is the line density), and over a range of Lundquist numbers S that approaches 10{sup 6}, the fluctuations scale as {delta}B/B {approx} S{sup -0.14}, the temperature scales as T {approx} I{sup 0.56}, the poloidal beta scales as {beta}{sub {theta}} {approx} I{sup -0.4}, and the energy confinement time scales as {tau}{sub E} {approx} I{sup 0.34}. The degradation of poloidal beta with current is a result of the weak scaling of the fluctuation level with the Lundquist number, and leads to the unfavorable scaling laws for temperature and energy confinement time. These results compare reasonably well with experimental data, and emphasize the need for external control of the dynamo fluctuations in the RFP. (2) Studies of feedback stabilization of resistive wall modes in the RFP were performed with the DEBS code in collaboration with the CNR/RFX group in Padua, Italy. The ideal growth rates are ''passively'' reduced by the presence of a resistive wall within the radius for perfectly conducting

  9. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Ten units which focus on subject-matter knowledge about energy and on the logic and strategy of problem-solving within science are provided in this user's guide. Each unit includes: a detailed summary of unit problems and activities; recommended grade levels and subject areas; possible learner outcomes and general goals; teacher background…

  10. A Portfolio of Energy Ideas: Science.

    ERIC Educational Resources Information Center

    Clark, Richard C., Ed.

    Ten units which focus on subject-matter knowledge about energy and on the logic and strategy of problem-solving within science are provided in this user's guide. Each unit includes: a detailed summary of unit problems and activities; recommended grade levels and subject areas; possible learner outcomes and general goals; teacher background…

  11. Contexts, concepts and cognition: principles for the transfer of basic science knowledge.

    PubMed

    Kulasegaram, Kulamakan M; Chaudhary, Zarah; Woods, Nicole; Dore, Kelly; Neville, Alan; Norman, Geoffrey

    2017-02-01

    Transfer of basic science aids novices in the development of clinical reasoning. The literature suggests that although transfer is often difficult for novices, it can be optimised by two complementary strategies: (i) focusing learners on conceptual knowledge of basic science or (ii) exposing learners to multiple contexts in which the basic science concepts may apply. The relative efficacy of each strategy as well as the mechanisms that facilitate transfer are unknown. In two sequential experiments, we compared both strategies and explored mechanistic changes in how learners address new transfer problems. Experiment 1 was a 2 × 3 design in which participants were randomised to learn three physiology concepts with or without emphasis on the conceptual structure of basic science via illustrative analogies and by means of one, two or three contexts during practice (operationalised as organ systems). Transfer of these concepts to explain pathologies in familiar organ systems (near transfer) and unfamiliar organ systems (far transfer) was evaluated during immediate and delayed testing. Experiment 2 examined whether exposure to conceptual analogies and multiple contexts changed how learners classified new problems. Experiment 1 showed that increasing context variation significantly improved far transfer performance but there was no difference between two and three contexts during practice. Similarly, the increased conceptual analogies led to higher performance for far transfer. Both interventions had independent but additive effects on overall performance. Experiment 2 showed that such analogies and context variation caused learners to shift to using structural characteristics to classify new problems even when there was superficial similarity to previous examples. Understanding problems based on conceptual structural characteristics is necessary for successful transfer. Transfer of basic science can be optimised by using multiple strategies that collectively emphasise

  12. Lost in Translation—Basic Science in the Era of Translational Research ▿

    PubMed Central

    Fang, Ferric C.; Casadevall, Arturo

    2010-01-01

    The concept of translational research, which aims to facilitate the application of basic scientific discoveries in clinical and community settings, is currently in vogue. While there are powerful forces driving this trend, support for translational research must be accompanied by a robust investment in basic science, which provides the essential raw material for translation and continues to represent humanity's best hope to meet a wide range of public health challenges. PMID:20038540

  13. Solar Energy Education. Renewable energy activities for earth science

    SciTech Connect

    Not Available

    1980-01-01

    A teaching manual is provided to aid teachers in introducing renewable energy topics to earth science students. The main emphasis is placed on solar energy. Activities for the student include a study of the greenhouse effect, solar gain for home heating, measuring solar radiation, and the construction of a model solar still to obtain fresh water. Instructions for the construction of apparatus to demonstrate a solar still, the greenhouse effect and measurement of the altitude and azimuth of the sun are included. (BCS)

  14. Information-seeking behavior of basic science researchers: implications for library services

    PubMed Central

    Haines, Laura L.; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A.

    2010-01-01

    Objectives: This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. Methods: A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. Results: The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Conclusions: Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository. PMID:20098658

  15. Information-seeking behavior of basic science researchers: implications for library services.

    PubMed

    Haines, Laura L; Light, Jeanene; O'Malley, Donna; Delwiche, Frances A

    2010-01-01

    This study examined the information-seeking behaviors of basic science researchers to inform the development of customized library services. A qualitative study using semi-structured interviews was conducted on a sample of basic science researchers employed at a university medical school. The basic science researchers used a variety of information resources ranging from popular Internet search engines to highly technical databases. They generally relied on basic keyword searching, using the simplest interface of a database or search engine. They were highly collegial, interacting primarily with coworkers in their laboratories and colleagues employed at other institutions. They made little use of traditional library services and instead performed many traditional library functions internally. Although the basic science researchers expressed a positive attitude toward the library, they did not view its resources or services as integral to their work. To maximize their use by researchers, library resources must be accessible via departmental websites. Use of library services may be increased by cultivating relationships with key departmental administrative personnel. Despite their self-sufficiency, subjects expressed a desire for centralized information about ongoing research on campus and shared resources, suggesting a role for the library in creating and managing an institutional repository.

  16. The Challenge of the Humanities and Social Science Education Through the Basic Seminar (Science of Snow Sports)

    NASA Astrophysics Data System (ADS)

    Taniai, Tetsuyuki; Sugimoto, Taku; Sato, Ken-Ichi; Ikota, Masaru

    The Education Center of Chiba Institute of Technology is taking a new approach to the introduction of liberal arts subjects commonly included in the curriculum of all departments through a newly established basic seminar, the Science of Snow Sports. Each faculty member has been working on setting up classes that cross the conventional boundaries of fields and disciplines and which are targeted at students of all faculties and departments. This paper describes the potential for teaching liberal arts and social science subjects to engineering students through the medium of sports science, based on actual experience gained via this new approach.

  17. The Basic Science of Bone Marrow Aspirate Concentrate in Chondral Injuries.

    PubMed

    Holton, James; Imam, Mohamed; Ward, Jonathan; Snow, Martyn

    2016-09-19

    There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.

  18. 78 FR 48863 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ... Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of... that the Fusion Energy Sciences Advisory Committee will be renewed for a two-year period beginning on August 2, 2013. The Committee will provide advice to the Office of Science (DOE), on long-range plans...

  19. Clinical and basic science teachers' opinions about the required depth of biomedical knowledge for medical students.

    PubMed

    Koens, Franciska; Custers, Eugène J F M; ten Cate, Olle T J

    2006-05-01

    The aim of the present study was to investigate whether basic scientists and physicians agree on the required depth of biomedical knowledge of medical students at graduation. A selection of basic science and clinical teachers rated the relevance of biomedical topics for students at graduation, illustrated by 80 example items. The items were derived from ten organ systems and designed at four levels: clinical, organ, cellular and molecular. Respondents were asked to identify for each item to what extent recently graduated medical students should have knowledge about it. In addition, they were asked to indicate whether the content of the item should be included in the medical curriculum. Analysis showed that basic scientists and physicians do not diverge at the clinical level. At the organ, cellular and molecular levels however, basic scientists judge that medical students should have more active knowledge. As expected, basic scientists also indicate that more deep level content should be included. Explanations for this phenomenon will be discussed.

  20. Basic Energy Conservation and Management Part 1: Looking at Lighting

    ERIC Educational Resources Information Center

    Krueger, Glenn

    2012-01-01

    Reducing school district energy expenditures has become a universal goal. However, school board members, superintendents, and directors of buildings and grounds are often unaware of the many options available to conserve energy. School energy conservation used to be relatively simple: turn off the lights and turn down the heat in the winter and…

  1. Basic Energy Conservation and Management--Part 2: HVAC

    ERIC Educational Resources Information Center

    Krueger, Glenn

    2012-01-01

    Reducing school district energy expenditures has become a universal goal, and new technologies have brought greater energy efficiencies to the school environment. In Part 1 of this two-part series, the author discussed the steps required to establish an energy conservation and management program with an emphasis on lighting. In this article, he…

  2. Basic Energy Conservation and Management--Part 2: HVAC

    ERIC Educational Resources Information Center

    Krueger, Glenn

    2012-01-01

    Reducing school district energy expenditures has become a universal goal, and new technologies have brought greater energy efficiencies to the school environment. In Part 1 of this two-part series, the author discussed the steps required to establish an energy conservation and management program with an emphasis on lighting. In this article, he…

  3. Basic Energy Conservation and Management Part 1: Looking at Lighting

    ERIC Educational Resources Information Center

    Krueger, Glenn

    2012-01-01

    Reducing school district energy expenditures has become a universal goal. However, school board members, superintendents, and directors of buildings and grounds are often unaware of the many options available to conserve energy. School energy conservation used to be relatively simple: turn off the lights and turn down the heat in the winter and…

  4. 76 FR 40714 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF ENERGY Fusion Energy Sciences Advisory Committee AGENCY: Department of Energy, Office of Science. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Fusion Energy Sciences...

  5. 78 FR 2259 - Fusion Energy Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Fusion Energy Sciences Advisory Committee AGENCY: Office of Science, Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Fusion Energy Sciences Advisory...

  6. Undergraduate Student Researchers, Preferred Learning Styles, and Basic Science Research: A Winning Combination

    ERIC Educational Resources Information Center

    Woeste, Lori A.; Barham, Beverly J.

    2007-01-01

    In basic science research, student researchers are often challenged with not only the technical portion of the research design but also the team dynamic. Understanding how a student prefers to learn can provide an advantage for mentors to better meet these challenges. In this article, the authors describe the experience of working with student…

  7. Effects of Concept Mapping Instruction Approach on Students' Achievement in Basic Science

    ERIC Educational Resources Information Center

    Ogonnaya, Ukpai Patricia; Okafor, Gabriel; Abonyi, Okechukwu S.; Ugama, J. O.

    2016-01-01

    The study investigated the effects of concept mapping on students' achievement in basic science. The study was carried out in Ebonyi State of Nigeria. The study employed a quasi-experimental design. Specifically the pretest posttest non-equivalent control group research design was used. The sample was 122 students selected from two secondary…

  8. Evaluation of a Basic Science, Peer Tutorial Program for First- and Second-Year Medical Students.

    ERIC Educational Resources Information Center

    Trevino, Fernando M.; Eiland, D. C., Jr.

    1980-01-01

    A peer tutorial program in the basic sciences implemented at the University of Texas Medical Branch at Galveston is evaluated. The grades of students receiving peer tutorials were analyzed and questionnaires were mailed to each participant soliciting their evaluation of services received. Future cost-benefit evaluations are planned. (Author/MLW)

  9. How do medical students in their clinical years perceive basic sciences courses at King Saud University?

    PubMed

    Alam, Awatif

    2011-01-01

    The inclusion of detailed basic science courses in medical school curricula has been a concern of students. The main objective of this study was to explore the attitudes of medical students towards basic sciences courses taught to them in the preclinical years and the applicability of these courses to current clinical practice. A cross-sectional survey was conducted during 2008-2009 among medical students in their clinical years at King Saud University, Riyadh, Saudi Arabia. Thirty percent of all students (n=314) were randomly selected to receive a questionnaire designed to evaluate their opinions about course load, ability to recall information, value of practical sessions, availability of references and course guidelines, and the applicability of individual courses to clinical practice. Students identified anatomy and pathology as the courses most overloaded with content (76% and 70%, respectively). Half of the students felt they retained the most knowledge of physiology (50%), while less than a quarter of students (19%) felt they retained the most information from biochemistry coursework. The role of practical sessions in facilitating theoretical understanding was more evident in anatomy (69%). Physiology was perceived as the subject with the highest applicability to clinical practice (66%), while pathology (29%) was identified as the subject with the least practical application. Students became increasingly negative in their opinions about basic science courses as they progressed through their medical education. Current attitudes of medical students towards their basic science courses indicate a need to reform the curricula so as to maximize the benefit of these courses.

  10. Improving College Faculty Instruction in the Basic and Allied Health Sciences.

    ERIC Educational Resources Information Center

    Washton, Nathan S.

    A project to improve college instruction in the basic and allied health sciences at New York Chiropractic College and the New York Institute of Technology is described. Attention was directed to: the kinds of resources colleges and professional schools provide to improve instruction; motivation of faculty to explore innovative or strategic…

  11. Integrating Basic Science and Clinical Teaching for Third-Year Medical Students.

    ERIC Educational Resources Information Center

    Croen, Lila G.; And Others

    1986-01-01

    A 2-month program for third-year students at Yeshiva's Albert Einstein College of Medicine that provides a model for integrating basic sciences and clinical training is described. It demonstrates the importance of lifelong learning in a field that constantly changes. (Author/MLW)

  12. Using "Basic Principles" to Understand Complex Science: Nicotine Smoke Chemistry and Literature Analogies

    ERIC Educational Resources Information Center

    Seeman, Jeffrey I.

    2005-01-01

    The chemical and physical properties of nicotine and its carboxylic acid salts found in tobacco provided as an interesting example to understand basic principles of complex science. The result showed that the experimental data used were inconsistent to the conclusion made, and the transfer of nicotine smoke from tobacco to smoke cannot be…

  13. Using "Basic Principles" to Understand Complex Science: Nicotine Smoke Chemistry and Literature Analogies

    ERIC Educational Resources Information Center

    Seeman, Jeffrey I.

    2005-01-01

    The chemical and physical properties of nicotine and its carboxylic acid salts found in tobacco provided as an interesting example to understand basic principles of complex science. The result showed that the experimental data used were inconsistent to the conclusion made, and the transfer of nicotine smoke from tobacco to smoke cannot be…

  14. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    ERIC Educational Resources Information Center

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2013-01-01

    Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…

  15. Integrating Basic Science and Clinical Teaching for Third-Year Medical Students.

    ERIC Educational Resources Information Center

    Croen, Lila G.; And Others

    1986-01-01

    A 2-month program for third-year students at Yeshiva's Albert Einstein College of Medicine that provides a model for integrating basic sciences and clinical training is described. It demonstrates the importance of lifelong learning in a field that constantly changes. (Author/MLW)

  16. Improving College Faculty Instruction in the Basic and Allied Health Sciences.

    ERIC Educational Resources Information Center

    Washton, Nathan S.

    A project to improve college instruction in the basic and allied health sciences at New York Chiropractic College and the New York Institute of Technology is described. Attention was directed to: the kinds of resources colleges and professional schools provide to improve instruction; motivation of faculty to explore innovative or strategic…

  17. Using a Database to Analyze Core Basic Science Content in a Problem-Based Curriculum.

    ERIC Educational Resources Information Center

    Rosen, Robert L.; And Others

    1992-01-01

    A study used computer analysis to examine distribution of basic science content in the 53 cases in the problem-based medical curriculum of Rush Medical College (Illinois) and compared it to application of that content by students and faculty. The method of analysis is recommended for reviewing curricula for omissions and redundancy. (Author/MSE)

  18. Pair Comparison Study of the Relevance of Nine Basic Science Courses

    ERIC Educational Resources Information Center

    Spilman, Edra L.; Spilman, Helen W.

    1975-01-01

    Reports a survey study in which basic science courses were rated according to relevance. Notes approaches for making the anatomy disciplines more relevant because results showed them of lowest relevancy compared with physiology, pathology, and pharmacology which were rated of highest relevance and with biochemistry and microbiology which fell…

  19. Evaluation of a Basic Science, Peer Tutorial Program for First- and Second-Year Medical Students.

    ERIC Educational Resources Information Center

    Trevino, Fernando M.; Eiland, D. C., Jr.

    1980-01-01

    A peer tutorial program in the basic sciences implemented at the University of Texas Medical Branch at Galveston is evaluated. The grades of students receiving peer tutorials were analyzed and questionnaires were mailed to each participant soliciting their evaluation of services received. Future cost-benefit evaluations are planned. (Author/MLW)

  20. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    ERIC Educational Resources Information Center

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2013-01-01

    Objective: To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease…

  1. Peer-Assisted Learning: Filling the Gaps in Basic Science Education for Preclinical Medical Students

    ERIC Educational Resources Information Center

    Sammaraiee, Yezen; Mistry, Ravi D.; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth

    2016-01-01

    In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United…

  2. Long-Term Retention of Basic Science Knowledge: A Review Study

    ERIC Educational Resources Information Center

    Custers, Eugene J. F. M.

    2010-01-01

    In this paper, a review of long-term retention of basic science knowledge is presented. First, it is argued that retention of this knowledge has been a long-standing problem in medical education. Next, three types of studies are described that are employed in the literature to investigate long-term retention of knowledge in general. Subsequently,…

  3. Peer-Assisted Learning: Filling the Gaps in Basic Science Education for Preclinical Medical Students

    ERIC Educational Resources Information Center

    Sammaraiee, Yezen; Mistry, Ravi D.; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth

    2016-01-01

    In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United…

  4. The double macchiato years; awards for the best basic science and epidemiology papers in 2012.

    PubMed

    Cullinan, Paul; Lloyd, Clare

    2013-08-01

    It's increasingly difficult to get published in Thorax so we commend all those who managed it in 2012; and salute all those who tried and failed. We think that comparisons are invidious but our chief editors, with all their schoolboy charm, disagree so here are our awards for the best basic science and epidemiological manuscripts in the year of the London Olympics.

  5. Effect of Self Regulated Learning Approach on Junior Secondary School Students' Achievement in Basic Science

    ERIC Educational Resources Information Center

    Nwafor, Chika E.; Obodo, Abigail Chikaodinaka; Okafor, Gabriel

    2015-01-01

    This study explored the effect of self-regulated learning approach on junior secondary school students' achievement in basic science. Quasi-experimental design was used for the study.Two co-educational schools were drawn for the study through simple random sampling technique. One school was assigned to the treatment group while the other was…

  6. An Analysis of Taiwanese Eighth Graders' Science Achievement, Scientific Epistemological Beliefs and Cognitive Structure Outcomes After Learning Basic Atomic Theory.

    ERIC Educational Resources Information Center

    Tsai, Chin-Chung

    1998-01-01

    Explores the interrelationships between students' general science achievement, scientific epistemological beliefs, and cognitive structure outcomes derived from instruction of basic atomic theory. Contains 19 references. (DDR)

  7. An Analysis of Taiwanese Eighth Graders' Science Achievement, Scientific Epistemological Beliefs and Cognitive Structure Outcomes After Learning Basic Atomic Theory.

    ERIC Educational Resources Information Center

    Tsai, Chin-Chung

    1998-01-01

    Explores the interrelationships between students' general science achievement, scientific epistemological beliefs, and cognitive structure outcomes derived from instruction of basic atomic theory. Contains 19 references. (DDR)

  8. Mesenchymal Stem Cells in Lipogems, a Reverse Story: from Clinical Practice to Basic Science.

    PubMed

    Tremolada, Carlo; Ricordi, Camillo; Caplan, Arnold I; Ventura, Carlo

    2016-01-01

    The idea that basic science should be the starting point for modern clinical approaches has been consolidated over the years, and emerged as the cornerstone of Molecular Medicine. Nevertheless, there is increasing concern over the low efficiency and inherent costs related to the translation of achievements from the bench to the bedside. These burdens are also perceived with respect to the effectiveness of translating basic discoveries in stem cell biology to the newly developing field of advanced cell therapy or Regenerative Medicine. As an alternative paradigm, past and recent history in Medical Science provides remarkable reverse stories in which clinical observations at the patient's bedside have fed major advances in basic research which, in turn, led to consistent progression in clinical practice. Within this context, we discuss our recently developed method and device, which forms the core of a system (Lipogems) for processing of human adipose tissue solely with the aid of mild mechanical forces to yield a microfractured tissue product.

  9. Clear and Present Atmospheric Science Foci for Wind Energy (Invited)

    NASA Astrophysics Data System (ADS)

    Poulos, G. S.

    2010-12-01

    The energy capacity of installed wind farms, with the exception of 2010, has grown at approximately 40% per year in the United States. Simultaneously, wind turbines have grown in height, rotor diameter and technological sophistication altering the time and space scales relevant to their operation. The meteorological phenomena and micrometeorological climatic conditions at turbine vertical scales, in the regions of the U. S. that have been developed, are different than those from which current wind turbine standards are derived. Some spectacular technological and performance failures have resulted, whose roots can be traced in part to a lack of knowledge transfer from atmospheric science to wind energy engineering and in part to knowledge gaps in atmospheric science. The result is that a wide variety of significant and meaningful basic and applied atmospheric science research topics are available to be addressed in the near term. To consolidate the discussion we will focus on two main areas: 1. Micrometeorological climatology for wind resource assessment, site suitability and wind turbine engineering standards, and, 2. Operational wind energy-focused numerical forecasting, forensics and efficiency.

  10. A hybrid model of mathematics support for science students emphasizing basic skills and discipline relevance

    NASA Astrophysics Data System (ADS)

    Jackson, Deborah C.; Johnson, Elizabeth D.

    2013-09-01

    The problem of students entering university lacking basic mathematical skills is a critical issue in the Australian higher-education sector and relevant globally. The Maths Skills programme at La Trobe University has been developed to address under preparation in the first-year science cohort in the absence of an institutional mathematics support centre. The programme was delivered through first-year science and statistics subjects with large enrolments and focused on basic mathematical skills relevant to each science discipline. The programme offered a new approach to the traditional mathematical support centre or class. It was designed through close collaboration between science subject coordinators and the project leader, a mathematician, and includes resources relevant to science and mathematics questions written in context. Evaluation of the programme showed it improved the confidence of the participating students who found it helpful and relevant. The programme was delivered through three learning modes to allow students to select activities most suitable for them, which was appreciated by students. Mathematics skills appeared to increase following completion of the programme and student participation in the programme correlated positively and highly with academic grades in their relevant science subjects. This programme offers an alternative model for mathematics support tailored to science disciplines.

  11. Care for child development: basic science rationale and effects of interventions.

    PubMed

    Holt, Rebecca L; Mikati, Mohamad A

    2011-04-01

    The past few years have witnessed increasing interest in devising programs to enhance early childhood development. We review current understandings of brain development, recent advances in this field, and their implications for clinical interventions. An expanding body of basic science laboratory data demonstrates that several interventions, including environmental enrichment, level of parental interaction, erythropoietin, antidepressants, transcranial magnetic stimulation, transcranial direct current stimulation, hypothermia, nutritional supplements, and stem cells, can enhance cerebral plasticity. Emerging clinical data, using functional magnetic resonance imaging and clinical evaluations, also support the hypothesis that clinical interventions can increase the developmental potential of children, rather than merely allowing the child to achieve an already predetermined potential. Such interventions include early developmental enrichment programs, which have improved cognitive function; high-energy and high-protein diets, which have increased brain growth in infants with perinatal brain damage; constraint-induced movement therapy, which has improved motor function in patients with stroke, cerebral palsy, and cerebral hemispherectomy; and transcranial magnetic stimulation, which has improved motor function in stroke patients.

  12. Energy Science and Technology Software Center

    SciTech Connect

    Kidd, E.M.

    1995-03-01

    The Energy Science and Technology Software Center (ESTSC), is the U.S. Department of Energy`s (DOE) centralized software management facility. It is operated under contract for the DOE Office of Scientific and Technical Information (OSTI) and is located in Oak Ridge, Tennessee. The ESTSC is authorized by DOE and the U.S. Nuclear Regulatory Commission (NRC) to license and distribute DOE-and NRC-sponsored software developed by national laboratories and other facilities and by contractors of DOE and NRC. ESTSC also has selected software from the Nuclear Energy Agency (NEA) of the Organisation for Economic Cooperation and Development (OECD) through a software exchange agreement that DOE has with the agency.

  13. United Nations/European Space Agency Workshops on Basic Space Science

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.

    1995-02-01

    In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica and Colombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.

  14. United Nations/European Space Agency Workshops on Basic Space Science

    NASA Technical Reports Server (NTRS)

    Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.

    1995-01-01

    In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica andColombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.

  15. United Nations/European Space Agency Workshops on Basic Space Science

    NASA Technical Reports Server (NTRS)

    Haubold, H. J.; Ocampo, A.; Torres, S.; Wamsteker, W.

    1995-01-01

    In 1958, the United Nations (UN) formally recognized a new potential for international cooperation by establishing an ad hoc Committee on the Peaceful Uses of Outer Space (COPUOS). A year later the Committee became a permanent body, and by 1983 membership had expanded to 53 states, with more than half of the members coming from the developing world. In 1970, COPUOS established the UN Program on Space Applications in order to strengthen cooperation in space science and technology between non-industrialized and industrialized countries. In the last few years, the UN and its COPUOS have paid increasing attention to education and research in space science and technology, including basic space science. In 1991 the UN, in cooperation with ESA, initiated the organization of annual Workshops in Basic Space Science for developing countries. These Workshops are designed to be held in one of the following major regions: Asia and the Pacific, Latin America and the Caribbean, Africa, Western Asia, and Europe. Accordingly, Basic Space Science Workshops have already been held in India (1991), Costa Rica andColombia (1992), and Nigeria (1993). The fourth Workshop was held from 27 June to 1 July 1994 at the Cairo University, in Egypt, for Western Asia.

  16. Utilization and acceptance of virtual patients in veterinary basic sciences - the vetVIP-project.

    PubMed

    Kleinsorgen, Christin; Kankofer, Marta; Gradzki, Zbigniew; Mandoki, Mira; Bartha, Tibor; von Köckritz-Blickwede, Maren; Naim, Hassan Y; Beyerbach, Martin; Tipold, Andrea; Ehlers, Jan P

    2017-01-01

    Context: In medical and veterinary medical education the use of problem-based and cased-based learning has steadily increased over time. At veterinary faculties, this development has mainly been evident in the clinical phase of the veterinary education. Therefore, a consortium of teachers of biochemistry and physiology together with technical and didactical experts launched the EU-funded project "vetVIP", to create and implement veterinary virtual patients and problems for basic science instruction. In this study the implementation and utilization of virtual patients occurred at the veterinary faculties in Budapest, Hannover and Lublin. Methods: This report describes the investigation of the utilization and acceptance of students studying veterinary basic sciences using optional online learning material concurrently to regular biochemistry and physiology didactic instruction. The reaction of students towards this offer of clinical case-based learning in basic sciences was analysed using quantitative and qualitative data. Quantitative data were collected automatically within the chosen software-system CASUS as user-log-files. Responses regarding the quality of the virtual patients were obtained using an online questionnaire. Furthermore, subjective evaluation by authors was performed using a focus group discussion and an online questionnaire. Results: Implementation as well as usage and acceptance varied between the three participating locations. High approval was documented in Hannover and Lublin based upon the high proportion of voluntary students (>70%) using optional virtual patients. However, in Budapest the participation rate was below 1%. Due to utilization, students seem to prefer virtual patients and problems created in their native language and developed at their own university. In addition, the statement that assessment drives learning was supported by the observation that peak utilization was just prior to summative examinations. Conclusion: Veterinary

  17. Utilization and acceptance of virtual patients in veterinary basic sciences – the vetVIP-project

    PubMed Central

    Kleinsorgen, Christin; Kankofer, Marta; Gradzki, Zbigniew; Mandoki, Mira; Bartha, Tibor; von Köckritz-Blickwede, Maren; Naim, Hassan Y.; Beyerbach, Martin; Tipold, Andrea; Ehlers, Jan P.

    2017-01-01

    Context: In medical and veterinary medical education the use of problem-based and cased-based learning has steadily increased over time. At veterinary faculties, this development has mainly been evident in the clinical phase of the veterinary education. Therefore, a consortium of teachers of biochemistry and physiology together with technical and didactical experts launched the EU-funded project “vetVIP”, to create and implement veterinary virtual patients and problems for basic science instruction. In this study the implementation and utilization of virtual patients occurred at the veterinary faculties in Budapest, Hannover and Lublin. Methods: This report describes the investigation of the utilization and acceptance of students studying veterinary basic sciences using optional online learning material concurrently to regular biochemistry and physiology didactic instruction. The reaction of students towards this offer of clinical case-based learning in basic sciences was analysed using quantitative and qualitative data. Quantitative data were collected automatically within the chosen software-system CASUS as user-log-files. Responses regarding the quality of the virtual patients were obtained using an online questionnaire. Furthermore, subjective evaluation by authors was performed using a focus group discussion and an online questionnaire. Results: Implementation as well as usage and acceptance varied between the three participating locations. High approval was documented in Hannover and Lublin based upon the high proportion of voluntary students (>70%) using optional virtual patients. However, in Budapest the participation rate was below 1%. Due to utilization, students seem to prefer virtual patients and problems created in their native language and developed at their own university. In addition, the statement that assessment drives learning was supported by the observation that peak utilization was just prior to summative examinations. Conclusion

  18. Aligning library instruction with the needs of basic sciences graduate students: a case study.

    PubMed

    O'Malley, Donna; Delwiche, Frances A

    2012-10-01

    How can an existing library instruction program be reconfigured to reach basic sciences graduate students and other patrons missed by curriculum-based instruction? The setting is an academic health sciences library that serves both the university and its affiliated teaching hospital. The existing program was redesigned to incorporate a series of seven workshops that encompassed the range of information literacy skills that graduate students in the basic sciences need. In developing the new model, the teaching librarians made changes in pedagogy, technology, marketing, and assessment strategies. Total attendance at the sessions increased substantially in the first 2 years of the new model, increasing from an average of 20 per semester to an average of 124. Survey results provided insight about what patrons wanted to learn and how best to teach it. Modifying the program's content and structure resulted in a program that appealed to the target audience.

  19. Aligning library instruction with the needs of basic sciences graduate students: a case study

    PubMed Central

    O'Malley, Donna; Delwiche, Frances A.

    2012-01-01

    Question: How can an existing library instruction program be reconfigured to reach basic sciences graduate students and other patrons missed by curriculum-based instruction? Setting: The setting is an academic health sciences library that serves both the university and its affiliated teaching hospital. Methods: The existing program was redesigned to incorporate a series of seven workshops that encompassed the range of information literacy skills that graduate students in the basic sciences need. In developing the new model, the teaching librarians made changes in pedagogy, technology, marketing, and assessment strategies. Results: Total attendance at the sessions increased substantially in the first 2 years of the new model, increasing from an average of 20 per semester to an average of 124. Survey results provided insight about what patrons wanted to learn and how best to teach it. Conclusion: Modifying the program's content and structure resulted in a program that appealed to the target audience. PMID:23133328

  20. Iron and Malaria Interactions: Research Needs From Basic Science to Global Policy12

    PubMed Central

    Cox, Sharon E.

    2012-01-01

    The resurgence in interest and concern regarding the potentially malign interactions between iron administration and malaria infections, especially in young children and pregnant women, has generated a research agenda that is both broad and deep. This paper highlights some of the key questions under 5 headings: basic science; clinical science and epidemiology; technological developments; country level planning; and global policy. At a time of unparalleled progress in basic science, which is illuminating the mechanisms by which iron interacts with infectious organisms, it is concluded that there are good medium-term prospects for achieving policy breakthroughs based on a secure foundation of disease-nutrient interactions. However, it is also stressed that there is much that can be done in the interim, especially in relation to health systems and implementation research that can empower systems to integrate iron interventions with programs for malaria prevention, surveillance, and treatment. PMID:22797996

  1. Interconnections of basic science research and product development in medical device design.

    PubMed

    Privitera, Mary Beth; Design, M; Johnson, Jeffrey

    2009-01-01

    The relationship between basic science research and product design/development are intertwined. This paper explores the definition of basic science and design as it relates to medical device development. It is intended to serve as a reference for both researchers and device developers to assist in trans-disciplinary collaborative efforts in improving patient care as each are of equal importance. The definition of a medical device is broad and varied. This paper is aimed towards those devices which interact with tissue and are rooted in the tenets of science. Both the scientific method and the design process are compared with similarities and opposites identified. The paper concludes identifying fundamental principles of medical device development and highlights the importance of both entities.

  2. A Bibliography of Basic Books on Atomic Energy. Update.

    ERIC Educational Resources Information Center

    Atomic Energy Commission, Washington, DC. Office of Information Services.

    This booklet, part of the United States Atomic Energy Commission's series of information booklets, lists selected commerically published books for the general public on atomic energy and closely related subjects. It includes annotated bibliographies for children (grade level indicated) and adults. The books are arranged by subject, alphabetized by…

  3. Changing educational needs of psychologists: do we need more medical knowledge, basic science and more psychological science?

    PubMed

    Belar, Cynthia D

    2008-03-01

    Psychologists of the 21st century must be highly skilled and versatile to function effectively in academic health centers (AHCs). Thus, the current paper focuses on the training psychologists receive to prepare them for their diverse roles in AHCs. The paper is framed around the question: Do we need more medical knowledge, basic science and more psychological science? posed to the author by the conference organizers of the 3rd National Association of Psychologists in Academic Health Centers (APAHC) Conference and is based on the perspective of the author.

  4. Operant conditioning of spinal reflexes: from basic science to clinical therapy

    PubMed Central

    Thompson, Aiko K.; Wolpaw, Jonathan R.

    2014-01-01

    New appreciation of the adaptive capabilities of the nervous system, recent recognition that most spinal cord injuries are incomplete, and progress in enabling regeneration are generating growing interest in novel rehabilitation therapies. Here we review the 35-year evolution of one promising new approach, operant conditioning of spinal reflexes. This work began in the late 1970’s as basic science; its purpose was to develop and exploit a uniquely accessible model for studying the acquisition and maintenance of a simple behavior in the mammalian central nervous system (CNS). The model was developed first in monkeys and then in rats, mice, and humans. Studies with it showed that the ostensibly simple behavior (i.e., a larger or smaller reflex) rests on a complex hierarchy of brain and spinal cord plasticity; and current investigations are delineating this plasticity and its interactions with the plasticity that supports other behaviors. In the last decade, the possible therapeutic uses of reflex conditioning have come under study, first in rats and then in humans. The initial results are very exciting, and they are spurring further studies. At the same time, the original basic science purpose and the new clinical purpose are enabling and illuminating each other in unexpected ways. The long course and current state of this work illustrate the practical importance of basic research and the valuable synergy that can develop between basic science questions and clinical needs. PMID:24672441

  5. Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicine.

    PubMed

    Nesse, Randolph M; Bergstrom, Carl T; Ellison, Peter T; Flier, Jeffrey S; Gluckman, Peter; Govindaraju, Diddahally R; Niethammer, Dietrich; Omenn, Gilbert S; Perlman, Robert L; Schwartz, Mark D; Thomas, Mark G; Stearns, Stephen C; Valle, David

    2010-01-26

    New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease.

  6. Operant conditioning of spinal reflexes: from basic science to clinical therapy.

    PubMed

    Thompson, Aiko K; Wolpaw, Jonathan R

    2014-01-01

    New appreciation of the adaptive capabilities of the nervous system, recent recognition that most spinal cord injuries are incomplete, and progress in enabling regeneration are generating growing interest in novel rehabilitation therapies. Here we review the 35-year evolution of one promising new approach, operant conditioning of spinal reflexes. This work began in the late 1970's as basic science; its purpose was to develop and exploit a uniquely accessible model for studying the acquisition and maintenance of a simple behavior in the mammalian central nervous system (CNS). The model was developed first in monkeys and then in rats, mice, and humans. Studies with it showed that the ostensibly simple behavior (i.e., a larger or smaller reflex) rests on a complex hierarchy of brain and spinal cord plasticity; and current investigations are delineating this plasticity and its interactions with the plasticity that supports other behaviors. In the last decade, the possible therapeutic uses of reflex conditioning have come under study, first in rats and then in humans. The initial results are very exciting, and they are spurring further studies. At the same time, the original basic science purpose and the new clinical purpose are enabling and illuminating each other in unexpected ways. The long course and current state of this work illustrate the practical importance of basic research and the valuable synergy that can develop between basic science questions and clinical needs.

  7. Reviewing a Manuscript: Disparity Amongst Peer Reviewers' Priorities from Basic Health Sciences and Clinicians.

    PubMed

    Baig, Saeeda; Ahmed, Sana; Attique, Hira

    2016-08-01

    To determine the disparities and the priorities of basic health scientists and clinicians while assessing a manuscript. Cross-sectional study. The study was conducted at Karachi, from January to April 2014. The study was a proforma-based research, employed convenient sampling for data collection, in which 100 reviewers belonging to clinical and basic health science background were selected. The questionnaire used was a selfadministered one with close-ended questions. The results were analysed using SPSS software. Out of 100 respondents, 50 were from Basic Health Sciences Reviewers (BRs) and 50 Clinicians Reviewers (CRs). The results depicted grammatical and improper referencing amongst formatting mistakes as the most common observation by the reviewers. The reviewers also raised concerns regarding validity of statistical analysis, use of outdated references and lack of acknowledgment of the sources of funding utilised by the authors. There were elements of manuscripts that BRs and CRs reviewers agreed upon and prioritised, but there were elements of the manuscript that they approached mostly in methods, results and conclusion components. The priorities of reviewers from Basic Health Sciences and Clinical background differed markedly in certain respects. This impacts how they review the manuscripts.

  8. Science and scientific literacy vs science and scientific awareness through basic physics lectures: A study of wish and reality

    NASA Astrophysics Data System (ADS)

    Rusli, Aloysius

    2012-06-01

    Scientific literacy was already discussed in the 1950s, as a prerequisite for the general citizen in a world increasingly served and infused by science and technology: the so-called knowledge or learning society. This kind of literacy has been described in detail by Victor Showalter in 1975, expanded by others, and later defined succinctly by the OECD in 2003. As a complement, science literacy is described also by the National Science Digital Library (NSDL) as a content knowledge needed in setting up practical models for handling daily matters with science and engineering. These important and worthy aims were studied, and compared with reality and existing conditions. One hypothesis put forward and argued for is, that it is more realistic, considering existing trends, to aim for scientific and science awareness for the general student, while scientific and science literacy remain important and worthy aims for the common good of the global community, and important to be strived for by teachers, lecturers and intellectuals. The Basic Physics lectures can also lend themselves usefully for the more realistic aim, due to the science-based nature of the present knowledge society.

  9. LSST Dark Energy Science Final Report

    SciTech Connect

    Asztalos, S

    2007-02-15

    Three decadal surveys recommend a large-aperture synoptic survey telescope (LSST) to allow time-domain and cosmological studies of distant objects. LLNL designed the optical system and also is expected to play a significant role in the engineering associated with the camera. Precision cosmology from ground-based instruments is in a sense terra incognita. Numerous systematic effects occur that would be minimal or absent in their space-based counterparts. We proposed developing some basic tools and techniques for investigating ''dark sector'' cosmological science with such next-generation, large-aperture, real-time telescopes. The critical research involved determining whether systematic effects might dominate the extremely small distortions (''shears'') in images of faint background galaxies. To address these issues we carried out a comprehensive data campaign and developed detailed computer simulations.

  10. Renewable energy and the atmospheric sciences

    NASA Astrophysics Data System (ADS)

    Nakajima, T. Y.; Takenaka, H.; Watanabe, T.; Nakajima, T.; Takamura, T.; Kurino, T.

    2013-12-01

    The demand for renewable energy in social energy systems has grown in recent years. In the atmospheric sciences, the energy balances and dynamics in the atmosphere are studied on both local and global scales, and thus estimation of renewable energy is an important practical application. For instance, shortwave solar radiation that reaches Earth's surface is an essential quantity for evaluating the photovoltaic (PV) power generation. Indeed, shortwave solar radiation can be calculated by a radiative transfer solver and an accurate electromagnetic wave scattering theory. A beneficial application of atmospheric sciences is obtaining of solar radiation on the basis of geostationary satellite measurements. Such satellites provide data covering most parts of the Earth every 30 min to 1 h. Geo-parameters such as cloud and aerosol properties are needed for calculating the amount of solar radiation that reaches Earth's surface. Multispectral images acquired by geostationary satellites allow for such geo-parameters to be evaluated. Additionally, polar-orbiting Earth observation satellites are also needed for improving data analysis techniques. For instance, multispectral imagers (e.g., MODIS) and cloud radars (e.g., CloudSat) aboard polar-orbiting satellites can be used to reveal the relationship between multispectral imaging results and the vertical structure of clouds. The EarthCARE (JAXA, ESA, NICT) and the GCOM-C (JAXA) satellites that will be launched in the middle of 2010-era are also used for improving cloud and aerosol process. This paper presents a method using satellite data to evaluate the optical and microphysical parameters of clouds that affect solar radiation. Also presented is a method for evaluating solar radiation that reaches Earth's surface. A new research project in Japan, JST-CREST-EMS (Energy Management System)-TEEDDA (Terrestrial Energy Estimation by Diurnal Data Analyses), which was started in October 2012, is also introduced.

  11. Interdisciplinary research in climate and energy sciences

    SciTech Connect

    Xu, Xiaofeng; Goswami, Santonu; Gulledge, Jay; Wullschleger, Stan D.; Thornton, Peter E.

    2015-09-12

    Due to the complex nature of climate change, interdisciplinary research approaches involving knowledge and skills from a broad range of disciplines have been adopted for studying changes in the climate system as well as strategies for mitigating climate change (i.e., greenhouse gas emissions reductions) and adapting to its impacts on society and natural systems. Harnessing of renewable energy sources to replace fossil fuels is widely regarded as a long-term mitigation strategy that requires the synthesis of knowledge from engineering, technology, and natural and social sciences. In this study, we examine how the adoption of interdisciplinary approaches has evolved over time and in different geographic regions. We conducted a comprehensive literature survey using an evaluation matrix of keywords, in combination with a word cloud analysis, to evaluate the spatiotemporal dynamics of scholarly discourse about interdisciplinary approaches to climate change and renewable energy research and development (R&D). Publications that discuss interdisciplinary approaches to climate change and renewable energy have substantially increased over the last 60 years; it appears, however, that the nature, timing, and focus of these publications vary across countries and through time. Over the most recent three decades, the country-level contribution to interdisciplinary research for climate change has become more evenly distributed, but this was not true for renewable energy research, which remained dominated by the United Sates and a few other major economies. The research topics have also evolved: Water resource management was emphasized from 1990s to 2000s, policy and adaptation were emphasized from the 2000s to 2010 – 2013, while vulnerability became prominent during the most recent years (2010 – 2013). Lastly, our analysis indicates that the rate of growth of interdisciplinary research for renewable energy lags behind that for climate change, possibly because knowledge

  12. Interdisciplinary research in climate and energy sciences

    DOE PAGES

    Xu, Xiaofeng; Goswami, Santonu; Gulledge, Jay; ...

    2015-09-12

    Due to the complex nature of climate change, interdisciplinary research approaches involving knowledge and skills from a broad range of disciplines have been adopted for studying changes in the climate system as well as strategies for mitigating climate change (i.e., greenhouse gas emissions reductions) and adapting to its impacts on society and natural systems. Harnessing of renewable energy sources to replace fossil fuels is widely regarded as a long-term mitigation strategy that requires the synthesis of knowledge from engineering, technology, and natural and social sciences. In this study, we examine how the adoption of interdisciplinary approaches has evolved over timemore » and in different geographic regions. We conducted a comprehensive literature survey using an evaluation matrix of keywords, in combination with a word cloud analysis, to evaluate the spatiotemporal dynamics of scholarly discourse about interdisciplinary approaches to climate change and renewable energy research and development (R&D). Publications that discuss interdisciplinary approaches to climate change and renewable energy have substantially increased over the last 60 years; it appears, however, that the nature, timing, and focus of these publications vary across countries and through time. Over the most recent three decades, the country-level contribution to interdisciplinary research for climate change has become more evenly distributed, but this was not true for renewable energy research, which remained dominated by the United Sates and a few other major economies. The research topics have also evolved: Water resource management was emphasized from 1990s to 2000s, policy and adaptation were emphasized from the 2000s to 2010 – 2013, while vulnerability became prominent during the most recent years (2010 – 2013). Lastly, our analysis indicates that the rate of growth of interdisciplinary research for renewable energy lags behind that for climate change, possibly because knowledge

  13. Assessment of the Fusion Energy Sciences Program. Final Report

    SciTech Connect

    2001-05-01

    An assessment of the Office of Fusion Energy Sciences (OFES) program with guidance for future program strategy. The overall objective of this study is to prepare an independent assessment of the scientific quality of the Office of Fusion Energy Sciences program at the Department of Energy. The Fusion Science Assessment Committee (FuSAC) has been appointed to conduct this study.

  14. Energy. Physical Science in Action. Teacher's Manual and Workbook.

    ERIC Educational Resources Information Center

    Sneider, Cary I.; Piccotto, Henri

    The Science in Action series is designed to teach practical science concepts to special-needs students. It is intended to develop students' problem-solving skills by teaching them to observe, record, analyze, conclude, and predict. This document contains a student workbook which deals with basic principles of physical science. Six separate units…

  15. Evaluation of Some Approved Basic Science and Technology Textbooks in Use in Junior Secondary Schools in Nigeria

    ERIC Educational Resources Information Center

    Nwafor, C. E.; Umoke, C. C.

    2016-01-01

    This study was designed to evaluate the content adequacy and readability of approved basic science and technology textbooks in use in junior secondary schools in Nigeria. Eight research questions guided the study. The sample of the study consisted of six (6) approved basic science and technology textbooks, 30 Junior Secondary Schools randomly…

  16. Adult-Rated Oceanography Part 1: A Project Integrating Ocean Sciences into Adult Basic Education Programs.

    NASA Astrophysics Data System (ADS)

    Cowles, S.; Collier, R.; Torres, M. K.

    2004-12-01

    Busy scientists seek opportunities to implement education and outreach efforts, but often don't know where to start. One easy and tested method is to form collaborations with federally-funded adult education and adult literacy programs. These programs exist in every U.S. state and territory and serve underrepresented populations through such major initiatives as adult basic education, adult secondary education (and GED preparation), and English language acquisition. These students are workers, consumers, voters, parents, grandparents, and members of every community. They have specific needs that are often overlooked in outreach activities. This presentation will describe the steps by which the Oregon Ocean Science and Math Collaborative program was developed. It is based on a partnership between the Oregon Department of Community Colleges and Workforce Development, Oregon State University College of Oceanic and Atmospheric Sciences, Oregon Sea Grant, and the OSU Hatfield Marine Science Center. It includes professional development through instructor institutes; teachers at sea and informal education opportunities; curriculum and web site development. Through the partnership described here, instructors in adult basic education programs participate in a yearlong experience in which they develop, test, and adapt innovative instructional strategies to meet the specific needs of adult learners. This, in turn, leads to new prospects for study in the areas of ocean science and math and introduces non-academic careers in marine science to a new community. Working directly with instructors, we have identified expertise level, instructional environment, instructor background and current teaching strategies used to address science literacy and numeracy goals of the adult learners in the State of Oregon. Preliminary evaluation of our ongoing project in meeting these goals will be discussed. These efforts contribute to national goals of science literacy for all, by providing

  17. Energy Frontier Research Center Materials Science of Actinides (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

    ScienceCinema

    Burns, Peter (Director, Materials Science of Actinides); MSA Staff

    2016-07-12

    'Energy Frontier Research Center Materials Science of Actinides' was submitted by the EFRC for Materials Science of Actinides (MSA) to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. MSA is directed by Peter Burns at the University of Notre Dame, and is a partnership of scientists from ten institutions.The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges.

  18. U.S. National Science Foundation Budget Proposal Focuses on Basic Research

    NASA Astrophysics Data System (ADS)

    Kumar, Mohi

    2008-03-01

    The budget request of the U.S. National Science Foundation (NSF) for fiscal year (FY) 2009 focuses attention on basic research, establishes and supports several cross-foundation investment projects designed to have a transformative impact across science and engineering, and puts foundation activities back on track to double their research budgets by the next decade. The foundation's total proposed budget is US$6.85 billion, an increase of 13% over that enacted for FY 2008. Most of this funding increase goes to NSF's Research and Related Activities (R&RA) account, which, at $5.59 billion, is $772.5 million above the FY 2008 enacted amount.

  19. Long-term retention of basic science knowledge: a review study.

    PubMed

    Custers, Eugène J F M

    2010-03-01

    In this paper, a review of long-term retention of basic science knowledge is presented. First, it is argued that retention of this knowledge has been a long-standing problem in medical education. Next, three types of studies are described that are employed in the literature to investigate long-term retention of knowledge in general. Subsequently, first the results of retention studies in general education are presented, followed by those of studies of basic science knowledge in medical education. The results of the review, in the general educational domain as well as in medical education, suggest that approximately two-third to three-fourth of knowledge will be retained after one year, with a further decrease to slightly below fifty percent in the next year. Finally, some recommendations are made for instructional strategies in curricula to improve long term retention of the subject matter dealt with.

  20. PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies.

    PubMed

    Zhou, Yiqin; Wang, James H-C

    2016-01-01

    Platelet-Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is controversial. This paper focuses on reviewing the basic science studies on PRP performed under well-controlled conditions. Both in vitro and in vivo studies describe PRP's anabolic and anti-inflammatory effects on tendons. While some clinical trials support these findings, others refute them. In this review, we discuss the effectiveness of PRP to treat tendon injuries with evidence presented in basic science studies and the potential reasons for the controversial results in clinical trials. Finally, we comment on the approaches that may be required to improve the efficacy of PRP treatment for tendinopathy.

  1. PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies

    PubMed Central

    2016-01-01

    Platelet-Rich Plasma (PRP) has been widely used in orthopaedic surgery and sport medicine to treat tendon injuries. However, the efficacy of PRP treatment for tendinopathy is controversial. This paper focuses on reviewing the basic science studies on PRP performed under well-controlled conditions. Both in vitro and in vivo studies describe PRP's anabolic and anti-inflammatory effects on tendons. While some clinical trials support these findings, others refute them. In this review, we discuss the effectiveness of PRP to treat tendon injuries with evidence presented in basic science studies and the potential reasons for the controversial results in clinical trials. Finally, we comment on the approaches that may be required to improve the efficacy of PRP treatment for tendinopathy. PMID:27610386

  2. Neutron transfer reactions: Surrogates for neutron capture for basic and applied nuclear science

    SciTech Connect

    Cizewski, J. A.; Jones, K. L.; Kozub, R. L.; Pain, Steven D; Peters, W. A.; Adekola, Aderemi S; Allen, J.; Bardayan, Daniel W; Becker, J.; Blackmon, Jeff C; Chae, K. Y.; Chipps, K.; Erikson, Luke; Gaddis, A. L.; Harlin, Christopher W; Hatarik, Robert; Howard, Joshua A; Jandel, M.; Johnson, Micah; Kapler, R.; Krolas, W.; Liang, J Felix; Livesay, Jake; Ma, Zhanwen; Matei, Catalin; Matthews, C.; Moazen, Brian; Nesaraja, Caroline D; O'Malley, Patrick; Patterson, N. P.; Paulauskas, Stanley; Pelham, T.; Pittman, S. T.; Radford, David C; Rogers, J.; Schmitt, Kyle; Shapira, Dan; ShrinerJr., J. F.; Sissom, D. J.; Smith, Michael Scott; Swan, T. P.; Thomas, J. S.; Vieira, D. J.; Wilhelmy, J. B.; Wilson, Gemma L

    2009-04-01

    Neutron capture reactions on unstable nuclei are important for both basic and applied nuclear science. A program has been developed at the Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory to study single-neutron transfer (d,p) reactions with rare isotope beams to provide information on neutron-induced reactions on unstable nuclei. Results from (d,p) studies on {sup 130,132}Sn, {sup 134}Te and {sup 75}As are discussed.

  3. Phenomenographic study of basic science understanding-senior medical students' conceptions of fatigue.

    PubMed

    Wilhelmsson, Niklas; Dahlgren, Lars Owe; Hult, Håkan; Wirell, Staffan; Ledin, Torbjörn; Josephson, Anna

    2013-01-01

    Helping students learn to apply their newly learned basic science knowledge to clinical situations is a long-standing challenge for medical educators. This study aims to describe how medical students' knowledge of the basic sciences is construed toward the end of their medical curriculum, focusing on how senior medical students explain the physiology of a given scenario. Methods A group of final-year medical students from two universities was investigated. Interviews were performed and phenomenographic analysis was used to interpret students' understanding of the physiology underlying the onset of fatigue in an individual on an exercise bicycle. Three categories of description depict the qualitatively different ways the students conceptualized fatigue. A first category depicts well integrated physiological and bio-chemical knowledge characterized by equilibrium and causality. The second category contains conceptions of finite amount of substrate and juxtaposition of physiological concepts that are not fully integrated. The third category exhibits a fragmented understanding of disparate sections of knowledge without integration of basic science and clinical knowledge. Distinctive conceptions of fatigue based with varying completeness of students' understanding characterized the three identified categories. The students' conceptions of fatigue were based on varying understanding of how organ systems relate and of the thresholds that determine physiological processes. Medical instruction should focus on making governing steps in biological processes clear and providing opportunity for causal explanations of clinical scenarios containing bio-chemical as well as clinical knowledge. This augments earlier findings by adding descriptions in terms of the subject matter studied about how basic science is applied by students in clinical settings.

  4. Very long-term retention of basic science knowledge in doctors after graduation.

    PubMed

    Custers, Eugène J F M; Ten Cate, Olle T J

    2011-04-01

    Despite frequent complaints that biomedical knowledge is quickly forgotten after it has been learned, few investigations of actual long-term retention of basic science knowledge have been conducted in the medical domain. Our aim was to illuminate the long-term retention of basic science knowledge, particularly of unrehearsed knowledge. Using a cross-sectional study design, medical students and doctors in the Netherlands were tested for retention of basic science knowledge. Relationships between retention interval and proportion of correct answers on a knowledge test were investigated. The popular notion that most of basic science knowledge is forgotten shortly after graduation is not supported by our findings. With respect to the full test scores, which reflect a composite of unrehearsed and rehearsed knowledge, performance decreased from approximately 40% correct answers for students still in medical school, to 25-30% correct answers for doctors after many years of practice. When rehearsal during the retention interval is controlled for, it appears that little knowledge is lost for 1.5-2 years after it was last used; from then on, retention is best described by a negatively accelerated (logarithmic) forgetting curve. After ≥ 25 years, retention levels were in the range of 15-20%. Conclusions about the forgetting of unrehearsed knowledge in this study are in line with findings reported in other domains: it proceeds in accordance with the Ebbinghaus curve for meaningful material, except that in our findings the 'downward' part appears to start later than in most other studies. The limitations of the study are discussed and possible ramifications for medical education are proposed. © Blackwell Publishing Ltd 2011.

  5. Association between pharmaceutical support and basic science research on erythropoiesis-stimulating agents.

    PubMed

    Bennett, Charles L; Lai, Stephen Y; Henke, Michael; Barnato, Sara E; Armitage, James O; Sartor, Oliver

    2010-09-13

    To our knowledge, no prior research has evaluated the association between pharmaceutical industry funding and basic science research results. When erythropoiesis-stimulating agents (ESAs) were licensed to treat chemotherapy-associated anemia, basic science concerns related to potential cancer stimulation were raised. We evaluated associations between pharmaceutical industry support and reported findings evaluating ESA effects on cancer cells. Articles identified in MEDLINE and EMBASE databases (1988-2008) investigating basic science findings related to ESA administration in the solid tumor setting were reviewed. Outcomes included information on erythropoietin receptors (EpoRs), Epo-induced signaling events, cellular function, and qualitative conclusions. Information on study funding (academic investigators with no reported funding from ESA manufacturers [64 studies], academic investigators with grant funding from ESA manufacturers [7 studies], and investigators employed by the ESA manufacturers [3 studies]) was evaluated. Some studies did not include information on each outcome. Investigators without funding from ESA manufacturers were more likely than academic investigators with such funding or investigators employed by ESA manufacturers to identify EpoRs on solid tumor cells (100%, 60%, and 67%, respectively; P = .009), Epo-induced signaling events (94%, 0%, and 0%, respectively; P = .001), or changes in cellular function (57%, 0%, and 0%, respectively; P = .007) and to conclude that ESAs had potentially harmful effects on cancer cells (57%, 0%, and 0%, respectively; P = .008). Researchers who do not have pharmaceutical industry support are more likely than those with pharmaceutical support to identify detrimental in vitro effects of ESAs. The potential for conflicts of interest to affect basic science research should be considered.

  6. Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies.

    PubMed

    Brookes, S J; Dinning, P G; Gladman, M A

    2009-12-01

    Colorectal physiology is complex and involves programmed, coordinated interaction between muscular and neuronal elements. Whilst a detailed understanding remains elusive, novel information has emerged from recent basic science and human clinical studies concerning normal sensorimotor mechanisms and the organization and function of the key elements involved in the control of motility. This chapter summarizes these observations to provide a contemporary review of the neuroanatomy and physiology of colorectal function and defaecation.

  7. Cassava: a basic energy source in the tropics

    SciTech Connect

    Cock, J.H.

    1982-11-19

    Cassava (Manihot esculenta) is the fourth most important source of food energy in the tropics. More than two-thirds of the total production of this crop is used as food for humans, with lesser amounts being used for animal feed and industrial purposes. The ingestion of high levels of cassava has been associated with chronic cyanide toxicity in parts of Africa, but this appears to be related to inadequate processing of the root and poor overall nutrition. Although cassava is not a complete food it is important as a cheap source of calories. The crop has a high yield potential under good conditions, and compared to other crops it excels under suboptimal conditions, thus offering the possibility of using marginal land to increase total agricultural production. Breeding programs that bring together germ plasm from different regions coupled with improved agronomic practices can markedly increase yields. The future demand for fresh cassava may depend on improved storage methods. The markets for cassava as a substitute for cereal flours in bakery products and as an energy source in animal feed rations are likely to expand. The use of cassava as a source of ethanol for fuel depends on finding an efficient source of energy for distillation or an improved method of separating ethanol from water. 7 figures, 8 tables.

  8. Invitations to the Matter-Energy Cycle. Teacher-Friendly Science Activities with Reproducible Handouts in English and Spanish. Grades 3-5. Living Things Science Series.

    ERIC Educational Resources Information Center

    Camp, Carole Ann, Ed.

    This booklet, one of six in the Living Things Science series, presents activities about matter and energy which address basic "Benchmarks" suggested by the American Association for the Advancement of Science for the Living Environment for grades 3-5. Contents include background information, vocabulary (in English and Spanish), materials,…

  9. Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials.

    PubMed

    An, G

    2001-10-01

    The management of Systemic Inflammatory Response Syndrome (SIRS)/Multiple Organ Failure (MOF) remains the greatest challenge in the field of critical care. There has been uniform difficulty in translating the results of basic science research into effective therapeutic regimes. We propose that this is due in part to a failure to account for the complex, nonlinear nature of the inflammatory process of which SIRS/MOF represents a disordered state. Attempts to manipulate this process without an understanding of the dynamics of the system may potentially produce unintended consequences. Agent-Based Computer Simulation (ABCS) provides a means to synthesize the information acquired from the linear analysis of basic science into a model that preserves the complexity of the inflammatory system. We have constructed an abstracted version of the inflammatory process using an ABCS that is based at the cellular level. Despite its abstraction, the simulation produces non-linear behavior and reproduces the dynamic structure of the inflammatory response. Furthermore, adjustment of the simulation to model one of the unsuccessful initial anti-inflammatory trials of the 1990's demonstrates the adverse outcome that was observed in those clinical trials. It must be emphasized that the current model is extremely abstract and simplified. However, it is hoped that future ABCSs of sufficient sophistication eventually may provide an important bridging tool to translate basic science discoveries into clinical applications. Creating these simulations will require a large collaborative effort, and it is hoped that this paper will stimulate interest in this form of analysis.

  10. Necessity of Accreditation Standards for Quality Assurance of Medical Basic Sciences

    PubMed Central

    Rezaeian, M; Jalili, Z; Nakhaee, N; Shirazi, J Jahroomi; Jafari, AR

    2013-01-01

    Background: The present article reviews the significance of accreditation standards while emphasizing the necessity of implementation of such standards by basic medical science council, with an eye on such international standards as those published by WFME. This review article had to decide on the key words and expressions, data bases, to review relevant literature, review higher and medical education journals at GOOGLE, ELSEVIER, PUBMED, and such web sites as those of WFME and WMA’s. Accreditation is a powerful leverage for institutional change and improvement and must be actively supported by academic and national health authorities worldwide. Considering the mission of the Basic Medical Science, Health and Post grad. Education, Ministry of Health and Medical Education, Tehran, Iran as accountable medical education, all specialists of the spectrum of disciplines agreed on the necessity of formulating the medical education standards for all disciplines of their interest. It is important that all efforts be joined in the endeavor to create effective and reliable instruments for quality assurance of Basic Medical Sciences Education. PMID:23865033

  11. Integrative cases for preclinical medical students: connecting clinical, basic science, and public health approaches.

    PubMed

    Schapiro, Renie; Stickford-Becker, Amy E; Foertsch, Julie A; Remington, Patrick L; Seibert, Christine S

    2011-10-01

    Healthcare and public health systems are each transforming, resulting in a need for better integration between clinical and population-based approaches to improve the health of populations. These changes also demand substantial transformations in the curriculum for medical students. Integrative Cases were designed for all first- and second-year medical students to provide them with more awareness, knowledge, and skills in integrating public health into clinical medicine. Each case examines basic science factors, clinical approaches, and public health determinants, including risk factors and direct and indirect contributing factors. This study was designed to evaluate the effectiveness of Integrative Cases in the medical student curriculum. Integrative Cases were formatively evaluated using standardized online post-event questionnaires emailed to students after each case. The questionnaires focused on goals specific to each case, ratings of particular sessions and facilitators, general impressions of the case, and student suggestions for improvement. Student evaluations indicate that Integrative Cases achieved their goals, especially providing experiences that offer a more expansive view of medicine and public health, stimulating interest and questions that anticipate future learning and making connections across basic science, medicine, and health. Students also indicated that these cases added to their understanding of public health issues and how to apply what they had learned to patient care. Integrative Cases demonstrate the effectiveness of a comprehensive approach that integrates clinical medicine with basic science and public health perspectives. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  12. Department of Energy Nanoscale Science Research Centers: Approach to Nanomaterial ES&H

    SciTech Connect

    None, None

    2008-05-12

    The following non-mandatory guidance is intended for the Nanoscale Science Research Centers (NSRCs) funded by the Basic Energy Sciences program office under the U.S. Department of Energy's Office of Science. It describes practices thought appropriate to the management of environmental, safety and health (ES&H) concerns associated with laboratory-scale operations involving the design, synthesis, or characterization of engineered nanomaterials, In general, it is intended to apply to precursors, intermediates, and wastes used during, or resulting from synthesizing such nanomaterials. In general, it is not intended to apply to materials for which an occupational exposure limit has been established.

  13. Perspective on Department of Energy Geospatial Science: Past, Present, and Future

    SciTech Connect

    Bhaduri, Budhendra L

    2007-01-01

    For many decades, the Department of Energy (DOE) has been a leader in basic scientific and engineering research that utilizes geospatial science to advance the state of knowledge in disciplines impacting national security, energy sustainability, and environmental stewardship. DOE recently established a comprehensive Geospatial Science Program that will provide an enterprise geographic information system infrastructure connecting all elements of DOE to critical geospatial data and associated geographic information services (GIServices). The Geospatial Science Program will provide a common platform for enhanced scientific and technical collaboration across DOE's national laboratories and facilities.

  14. Energy from biomass — Some basic physical and related considerations

    NASA Astrophysics Data System (ADS)

    Gloyne, R. W.

    1983-09-01

    The production of vegetable matter (biomass) by photosynthesis is determined by species and by meteorological factors (especially, but not exclusively, solar radiation). Annual net primary production of land-based biomass corresponds to only about 1/1000 of the intercepted irradiation at ground level, but even so, is 10 times the world's estimated energy needs. The exploitation of this energy potential at any one place is critically influenced by the economic, political and social factors, amongst which are the competition from agriculture (especially food crops), forestry, industrial and urban (including leisure) needs for land and resources. Social factors (e.g. population and population density) also constitute prime influences. Strategies for utilisation range from the cultivation of special energy crops (readily conceivable on the American/ Australasian continents); to the more efficient manipulation of current land-use patterns (including “opportunity” cropping); to the more effective exploitation of biologi cal wastes (e.g. methane from sewage), probably the only immediately practical possibility in any densely populated and highly industrialised country. The spatial pattern of solar irradiation at ground level is complex. In the summer, total daily irradiation in continental high latitudes can exceed that in maritime temperate regions; and this combined with species differences and the almost infinite variety of shape and orientation of plant parts, result in a photosynthetic production of biomass which does not conform completely to a zonal pattern, but in broad terms annual dry matter production varies from a few kg/ha in Arctic Tundra to tens of tonnes in temperate latitudes rising to nearly 100 t/ha for perennial tropical crops. If a species could be developed to grow throughout the year at the current seasonal rate, a yield of 150 t/yr, ha) seems possible.

  15. Statistical Energy Analysis for Designers. Part 1. Basic Theory

    DTIC Science & Technology

    1974-09-01

    the various energy storage elements or mode groups. As noted above, this amounts to solving a set of linear algebraic equations, one equation to each...undamped string, p = lineal density, r = 0, and A=-T(D/ax) 2. Thus, Eq. (2.3.2) becomes Tk2 = pw2, or k = ±w/c , (2.3.3) where c=VT- is the speed of...systems, then our impedances would have become matrices involving both force and moment terms, but the structure of the result would remain the same. The

  16. Movement as a basic concept in physiotherapy--a human science approach.

    PubMed

    Wikström-Grotell, Camilla; Eriksson, Katie

    2012-08-01

    The development of scientific knowledge of physiotherapy (PT) has advanced significantly. Research is mostly conducted within a biomedical paradigm and theory-building is underpinned by a positivist paradigm. The basic philosophical questions and concepts are not much reflected on, and PT lacks an established theoretical frame. The first step in theory development is to define the basic concepts. The aim of this professional theoretical paper was to reflect on and describe the concept of movement in PT based on earlier research as a standpoint for a broader and deeper understanding of the complex nature of PT reality inspired by a model for concept analysis developed in caring science [Eriksson K 2010 Concept determination as part of the development of knowledge in caring science. Scandinavian Journal of Caring Sciences 24: 2-11]. The concept of movement in PT is conceptualized as complex and multidimensional. The understanding of human movement in PT is based on five categories described in the paper. The conceptualization of movement includes acting in relation to the socio-cultural environment, inter-dynamic aspects, as well as personal, intradynamic aspects. This paper argues for the need to further develop the concept of movement in PT within a human science approach. A deeper understanding is needed as a basis for understanding complex clinical practice as well as in shaping the PT discipline.

  17. Integrating Basic Analytical Methods and Computer-Interface Technology into an Environmental Science Water Quality Lab Improves Student Attitude

    ERIC Educational Resources Information Center

    Carvalho-Knighton, Kathleen M.; Smoak, Joseph M.

    2009-01-01

    The aim of this study was to investigate if integrating basic analytical methods and computer interface technology would result in a positive change in student attitude. Students' self-concept of science knowledge and skills (Capability), opinion towards science (Affect), and perceptions of the value of science (Value) were determined with…

  18. The Future of Basic Science in Academic Surgery: Identifying Barriers to Success for Surgeon-scientists.

    PubMed

    Keswani, Sundeep G; Moles, Chad M; Morowitz, Michael; Zeh, Herbert; Kuo, John S; Levine, Matthew H; Cheng, Lily S; Hackam, David J; Ahuja, Nita; Goldstein, Allan M

    2017-06-01

    The aim of this study was to examine the challenges confronting surgeons performing basic science research in today's academic surgery environment. Multiple studies have identified challenges confronting surgeon-scientists and impacting their ability to be successful. Although these threats have been known for decades, the downward trend in the number of successful surgeon-scientists continues. Clinical demands, funding challenges, and other factors play important roles, but a rigorous analysis of academic surgeons and their experiences regarding these issues has not previously been performed. An online survey was distributed to 2504 members of the Association for Academic Surgery and Society of University Surgeons to determine factors impacting success. Survey results were subjected to statistical analyses. We also reviewed publicly available data regarding funding from the National Institutes of Health (NIH). NIH data revealed a 27% decline in the proportion of NIH funding to surgical departments relative to total NIH funding from 2007 to 2014. A total of 1033 (41%) members responded to our survey, making this the largest survey of academic surgeons to date. Surgeons most often cited the following factors as major impediments to pursuing basic investigation: pressure to be clinically productive, excessive administrative responsibilities, difficulty obtaining extramural funding, and desire for work-life balance. Surprisingly, a majority (68%) did not believe surgeons can be successful basic scientists in today's environment, including departmental leadership. We have identified important barriers that confront academic surgeons pursuing basic research and a perception that success in basic science may no longer be achievable. These barriers need to be addressed to ensure the continued development of future surgeon-scientists.

  19. Internal Medicine Clerkship Directors' opinion regarding clinical input in the preclinical years: the 2002 CDIM basic science survey results.

    PubMed

    O'Brien, Kevin; Crespo, Lynn; Wallach, Paul; Elnicki, Michael

    2006-01-01

    Input from both basic science and clinical faculty members is needed to promote further integration of medical curricula. To assess current views of clerkship directors about the role and relationship of the basic sciences to clinical years in medical education. As part of the 2002 Annual CDIM Survey, questions regarding basic science curriculum were included; 89 of 123 CDIM members responded (72%). Overall, respondents felt participation from both basic science and clinical faculty members is necessary to define basic science course content. Nearly 89% of clerkship directors indicated curricular review should be collaborative and interdepartmental; 93% felt that this review effort should occur frequently. Supporting the growing philosophy that the structure of the preclinical years should involve increased clinically relevant integration, 58% favored an integrated organ system approach rather than the traditional departmental structure (18%). In addition, in order of ranking, respondents felt that small group (M = 2.0 +/- 0.9) and problem-based learning (M = 2.1 +/- 1.1) are better approaches than the standard lecture format (M = 2.8 +/- 1.2). Although clerkship directors recognized the need for increased clinical input in the preclinical years, many reported a lack of knowledge regarding the amount of clinical exposure students received in the basic science years (33%), frequency of peer review of the basic science courses (20%), and who performed peer review of the basic science courses at their institution (36%). Medical clerkship directors believe that basic science education should be developed collaboratively, organized by organ system, and presented in small groups.

  20. Basic Science Evidence for the Link Between Erectile Dysfunction and Cardiometabolic Dysfunction

    PubMed Central

    Musicki, Biljana; Bella, Anthony J.; Bivalacqua, Trinity J.; Davies, Kelvin P.; DiSanto, Michael E.; Gonzalez-Cadavid, Nestor F.; Hannan, Johanna L.; Kim, Noel N.; Podlasek, Carol A.; Wingard, Christopher J.; Burnett, Arthur L.

    2016-01-01

    Introduction Although clinical evidence supports an association between cardiovascular/metabolic diseases (CVMD) and erectile dysfunction (ED), scientific evidence for this link is incompletely elucidated. Aim This study aims to provide scientific evidence for the link between CVMD and ED. Methods In this White Paper, the Basic Science Committee of the Sexual Medicine Society of North America assessed the current literature on basic scientific support for a mechanistic link between ED and CVMD, and deficiencies in this regard with a critical assessment of current preclinical models of disease. Results A link exists between ED and CVMD on several grounds: the endothelium (endothelium-derived nitric oxide and oxidative stress imbalance); smooth muscle (SM) (SM abundance and altered molecular regulation of SM contractility); autonomic innervation (autonomic neuropathy and decreased neuronal-derived nitric oxide); hormones (impaired testosterone release and actions); and metabolics (hyperlipidemia, advanced glycation end product formation). Conclusion Basic science evidence supports the link between ED and CVMD. The Committee also highlighted gaps in knowledge and provided recommendations for guiding further scientific study defining this risk relationship. This endeavor serves to develop novel strategic directions for therapeutic interventions. PMID:26646025

  1. Basic Science Evidence for the Link Between Erectile Dysfunction and Cardiometabolic Dysfunction.

    PubMed

    Musicki, Biljana; Bella, Anthony J; Bivalacqua, Trinity J; Davies, Kelvin P; DiSanto, Michael E; Gonzalez-Cadavid, Nestor F; Hannan, Johanna L; Kim, Noel N; Podlasek, Carol A; Wingard, Christopher J; Burnett, Arthur L

    2015-12-01

    Although clinical evidence supports an association between cardiovascular/metabolic diseases (CVMD) and erectile dysfunction (ED), scientific evidence for this link is incompletely elucidated. This study aims to provide scientific evidence for the link between CVMD and ED. In this White Paper, the Basic Science Committee of the Sexual Medicine Society of North America assessed the current literature on basic scientific support for a mechanistic link between ED and CVMD, and deficiencies in this regard with a critical assessment of current preclinical models of disease. A link exists between ED and CVMD on several grounds: the endothelium (endothelium-derived nitric oxide and oxidative stress imbalance); smooth muscle (SM) (SM abundance and altered molecular regulation of SM contractility); autonomic innervation (autonomic neuropathy and decreased neuronal-derived nitric oxide); hormones (impaired testosterone release and actions); and metabolics (hyperlipidemia, advanced glycation end product formation). Basic science evidence supports the link between ED and CVMD. The Committee also highlighted gaps in knowledge and provided recommendations for guiding further scientific study defining this risk relationship. This endeavor serves to develop novel strategic directions for therapeutic interventions. © 2015 International Society for Sexual Medicine.

  2. The Neuropsychoanalytic Approach: Using Neuroscience as the Basic Science of Psychoanalysis

    PubMed Central

    Johnson, Brian; Flores Mosri, Daniela

    2016-01-01

    Neuroscience was the basic science behind Freud's psychoanalytic theory and technique. He worked as a neurologist for 20 years before being aware that a new approach to understand complex diseases, namely the hysterias, was needed. Solms coined the term neuropsychoanalysis to affirm that neuroscience still belongs in psychoanalysis. The neuropsychoanalytic field has continued Freud's original ideas as stated in 1895. Developments in psychoanalysis that have been created or revised by the neuropsychoanalysis movement include pain/relatedness/opioids, drive, structural model, dreams, cathexis, and dynamic unconscious. Neuroscience has contributed to the development of new psychoanalytic theory, such as Bazan's (2011) description of anxiety driven by unconscious intentions or “phantoms.” Results of adopting the “dual aspect monism” approach of idiographic psychoanalytic clinical observation combined with nomothetic investigation of related human phenomena include clarification and revision of theory, restoration of the scientific base of psychoanalysis, and improvement of clinical treatments. By imbricating psychoanalytic thinking with neuroscience, psychoanalysts are also positioned to make contributions to neuroscience research. Freud's original Project for a Scientific Psychology/Psychology for Neurologists can be carried forward in a way that moves psychoanalysis into the twenty-first century as a core contemporary science (Kandel, 1999). Neuroscience as the basic science of psychoanalysis both improves the field, and enhances its scientific and cultural status. PMID:27790160

  3. The Neuropsychoanalytic Approach: Using Neuroscience as the Basic Science of Psychoanalysis.

    PubMed

    Johnson, Brian; Flores Mosri, Daniela

    2016-01-01

    Neuroscience was the basic science behind Freud's psychoanalytic theory and technique. He worked as a neurologist for 20 years before being aware that a new approach to understand complex diseases, namely the hysterias, was needed. Solms coined the term neuropsychoanalysis to affirm that neuroscience still belongs in psychoanalysis. The neuropsychoanalytic field has continued Freud's original ideas as stated in 1895. Developments in psychoanalysis that have been created or revised by the neuropsychoanalysis movement include pain/relatedness/opioids, drive, structural model, dreams, cathexis, and dynamic unconscious. Neuroscience has contributed to the development of new psychoanalytic theory, such as Bazan's (2011) description of anxiety driven by unconscious intentions or "phantoms." Results of adopting the "dual aspect monism" approach of idiographic psychoanalytic clinical observation combined with nomothetic investigation of related human phenomena include clarification and revision of theory, restoration of the scientific base of psychoanalysis, and improvement of clinical treatments. By imbricating psychoanalytic thinking with neuroscience, psychoanalysts are also positioned to make contributions to neuroscience research. Freud's original Project for a Scientific Psychology/Psychology for Neurologists can be carried forward in a way that moves psychoanalysis into the twenty-first century as a core contemporary science (Kandel, 1999). Neuroscience as the basic science of psychoanalysis both improves the field, and enhances its scientific and cultural status.

  4. The United Nations Basic Space Science Initiative (UNBSSI): A Historical Introduction

    NASA Astrophysics Data System (ADS)

    Haubold, H. J.

    2006-11-01

    Pursuant to recommendations of the Third United Nations Conference on the Exploration and Peaceful Uses of Outer Space (UNISPACE III) and deliberations of the United Nations Committee on the Peaceful Uses of Outer Space (UNCOPUOS), annual UN/European Space Agency workshops on basic space science have been held around the world since 1991. These workshops contributed to the development of astrophysics and space science, particularly in developing nations. Following a process of prioritization, the workshops identified the following elements as particularly important for international cooperation in the field: (i) operation of astronomical telescope facilities implementing TRIPOD, (ii) virtual observatories, (iii) astrophysical data systems, (iv) con-current design capabilities for the development of international space missions, and (v) theoretical astrophysics such as applications of non-extensive statistical mechanics. Beginning in 2005, the workshops are focusing on preparations for the International Heliophysical Year 2007 (IHY2007). The workshops continue to facilitate the establishment of astronomical telescope facilities as pursued by Japan and the development of low-cost, ground-based, world- wide instrument arrays as led by the IHY secretariat. Wamsteker, W., Albrecht, R. and Haubold, H.J.: Developing Basic Space Science World-Wide: A Decade of UN/ESA Workshops: Kluwer Academic Publishers, Dordrecht 2004. http://ihy2007.org http://www.unoosa.org/oosa/en/SAP/bss/ihy2007/index.html http://www.cbpf.br/GrupPesq/StatisticalPhys/biblio.htm

  5. Assessing Understanding of the Energy Concept in Different Science Disciplines

    ERIC Educational Resources Information Center

    Park, Mihwa; Liu, Xiufeng

    2016-01-01

    Energy is one of the most central and richly connected ideas across all science disciplines. The purpose of this study was to develop a measurement instrument for assessing students' understanding of the energy concept within and across different science disciplines. To achieve this goal, the Inter-Disciplinary Energy concept Assessment (IDEA) was…

  6. Energy Monitoring: Powerful Connections between Math, Science, and Community

    ERIC Educational Resources Information Center

    Farrin, Lynn; Mokros, Jan

    2012-01-01

    Middle school students need to know about energy concepts and how they can reduce their energy use. New energy-monitoring tools provide powerful opportunities for students to engage in authentic investigations rich in the science practices described in "A Framework for K-12 Science Education" (NRC 2012), while at the same time advancing their…

  7. Assessing Understanding of the Energy Concept in Different Science Disciplines

    ERIC Educational Resources Information Center

    Park, Mihwa; Liu, Xiufeng

    2016-01-01

    Energy is one of the most central and richly connected ideas across all science disciplines. The purpose of this study was to develop a measurement instrument for assessing students' understanding of the energy concept within and across different science disciplines. To achieve this goal, the Inter-Disciplinary Energy concept Assessment (IDEA) was…

  8. The articulation of integration of clinical and basic sciences in concept maps: differences between experienced and resident groups.

    PubMed

    Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan

    2016-08-01

    To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic science concepts and these basic science concepts are expected to be used for the organization of the maps. These hypotheses are derived from studies about knowledge development of individuals. However, integrated curricula require a high degree of cooperation between clinicians and basic scientists. This study examined whether there are consistent variations regarding the articulation of integration when groups of experienced clinicians and basic scientists and groups of residents and basic scientists-in-training construct concept maps. Seven groups of three clinicians and basic scientists on experienced level and seven such groups on resident level constructed concept maps illuminating clinical problems. They were guided by instructions that focused them on articulation of integration. The concept maps were analysed by features that described integration. Descriptive statistics showed consistent variations between the two expertise levels. The concept maps of the resident groups exceeded those of the experienced groups in articulated integration. First, they used significantly more links between clinical and basic science concepts. Second, these links connected basic science concepts with a greater variety of clinical concepts than the experienced groups. Third, although residents did not use significantly more basic science concepts, they used them significantly more frequent to organize the clinical concepts. The conclusion was drawn that not all hypotheses could be confirmed and that the resident concept maps were more elaborate than expected. This article discusses the implications for the role that residents and

  9. The relationship between immediate relevant basic science knowledge and clinical knowledge: physiology knowledge and transthoracic echocardiography image interpretation.

    PubMed

    Nielsen, Dorte Guldbrand; Gotzsche, Ole; Sonne, Ole; Eika, Berit

    2012-10-01

    Two major views on the relationship between basic science knowledge and clinical knowledge stand out; the Two-world view seeing basic science and clinical science as two separate knowledge bases and the encapsulated knowledge view stating that basic science knowledge plays an overt role being encapsulated in the clinical knowledge. However, resent research has implied that a more complex relationship between the two knowledge bases exists. In this study, we explore the relationship between immediate relevant basic science (physiology) and clinical knowledge within a specific domain of medicine (echocardiography). Twenty eight medical students in their 3rd year and 45 physicians (15 interns, 15 cardiology residents and 15 cardiology consultants) took a multiple-choice test of physiology knowledge. The physicians also viewed images of a transthoracic echocardiography (TTE) examination and completed a checklist of possible pathologies found. A total score for each participant was calculated for the physiology test, and for all physicians also for the TTE checklist. Consultants scored significantly higher on the physiology test than did medical students and interns. A significant correlation between physiology test scores and TTE checklist scores was found for the cardiology residents only. Basic science knowledge of immediate relevance for daily clinical work expands with increased work experience within a specific domain. Consultants showed no relationship between physiology knowledge and TTE interpretation indicating that experts do not use basic science knowledge in routine daily practice, but knowledge of immediate relevance remains ready for use.

  10. Peer-assisted learning: filling the gaps in basic science education for preclinical medical students.

    PubMed

    Sammaraiee, Yezen; Mistry, Ravi D; Lim, Julian; Wittner, Liora; Deepak, Shantal; Lim, Gareth

    2016-09-01

    In contrast to peer-assisted learning (PAL) in clinical training, there is scant literature on the efficacy of PAL during basic medical sciences teaching for preclinical students. A group of senior medical students aimed to design and deliver clinically oriented small-group tutorials after every module in the preclinical curriculum at a United Kingdom medical school. Twenty tutorials were delivered by senior students throughout the year to first- and second-year students. A baseline questionnaire was delivered to inform the development of the program followed by an end-point questionnaire the next year (n = 122). Quizzes were administered before and after five separate tutorials to assess changes in mean student scores. Additionally, each tutorial was evaluated via a questionnaire for participants (n = 949). All five posttutorial quizzes showed a significant improvement in mean student score (P < 0.05). Questionnaires showed students found the program to be relevant and useful for revision purposes and appreciated how tutorials contextualized basic science to clinical medicine. Students appreciated the interactive nature of the sessions and found receiving personalized feedback about their learning and consolidating information with someone familiar with the material to be useful. With the inclusion of the program, students felt there were now an adequate number of tutorials during the year. In conclusion, this study shows that senior medical students can design and deliver a program that adds value to the mostly lecture-based formal preclinical curriculum. We hope that our study can prompt further work to explore the effect of PAL on the teaching of basic sciences during preclinical studies.

  11. Vertical integration of basic science in final year of medical education.

    PubMed

    Rajan, Sudha Jasmine; Jacob, Tripti Meriel; Sathyendra, Sowmya

    2016-01-01

    Development of health professionals with ability to integrate, synthesize, and apply knowledge gained through medical college is greatly hampered by the system of delivery that is compartmentalized and piecemeal. There is a need to integrate basic sciences with clinical teaching to enable application in clinical care. To study the benefit and acceptance of vertical integration of basic science in final year MBBS undergraduate curriculum. After Institutional Ethics Clearance, neuroanatomy refresher classes with clinical application to neurological diseases were held as part of the final year posting in two medical units. Feedback was collected. Pre- and post-tests which tested application and synthesis were conducted. Summative assessment was compared with the control group of students who had standard teaching in other two medical units. In-depth interview was conducted on 2 willing participants and 2 teachers who did neurology bedside teaching. Majority (>80%) found the classes useful and interesting. There was statistically significant improvement in the post-test scores. There was a statistically significant difference between the intervention and control groups' scores during summative assessment (76.2 vs. 61.8 P < 0.01). Students felt that it reinforced, motivated self-directed learning, enabled correlations, improved understanding, put things in perspective, gave confidence, aided application, and enabled them to follow discussions during clinical teaching. Vertical integration of basic science in final year was beneficial and resulted in knowledge gain and improved summative scores. The classes were found to be useful, interesting and thought to help in clinical care and application by majority of students.

  12. How We Make Energy Work: Grades 4, 5, 6 Science.

    ERIC Educational Resources Information Center

    National Science Teachers Association, Washington, DC.

    This packet of units is designed to focus on the technological aspects of energy. Four units are presented, with from 1-4 lessons included in each unit. Units include: (1) basic concepts and applications of energy; (2) steps and processes of energy production and transmission; (3) fuel acquisition; and (4) energy futures and application of…

  13. The Basic Science of Behavior Change and Its Application to Pediatric Providers.

    PubMed

    Love, Allison R; Jensen, Peter S; Khan, Lisa; Brandt, Tiffany West; Jaccard, James

    2017-10-01

    Pediatric primary care providers (PPCPs) are increasingly expected to know how to assess, diagnose, and treat a wide range of mental health problems in children and adolescents. For many PPCPs, this means learning and performing new practice behaviors that were not taught in their residency training. Typical continuing education approaches to engage PPCPs in new practices have not yielded the desired changes in provider behavior. This article summarizes behavior change principles identified through basic behavior science, adult education, and communication research, and discusses their application to a patient-centered pediatric primary care mental health curriculum. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Noninvasive Cardiovascular Imaging Techniques for Basic Science Research: Application to Cellular Therapeutics

    PubMed Central

    Gilson, Wesley D.; Kraitchman, Dara L.

    2010-01-01

    Cell therapy continues to be an active area of basic science research with early promise in the treatment of cardiovascular diseases. However, there are many unknowns including the mechanisms by which they work, the most useful cell types, the most efficient delivery strategies, and their safety. Noninvasive imaging provides a wide array of tools to quantitatively address many of these unknowns. This article reviews echocardiography, magnetic resonance imaging, computed tomography, positron emission tomography and single photon emission tomography in the context of imaging cellular therapeutics to demonstrate how these modalities are being used to answer some of these questions. PMID:19706247

  15. [Three-dimensional cell cultures. Applications in basic science and biotechnology].

    PubMed

    Kitel, Radosław; Czarnecka, Joanna; Rusin, Aleksandra

    2013-01-01

    The tissue culture technique is widely used in biochemical and molecular studies, offering accessibility to biological material, high reproducibility of results and high throughput format, comparing with organ cultures. However, traditional, two-dimensional cultures (2D cultures) poorly represent the microenvironment of a tissue, and they are gradually replaced with 3D cultures, that enable formation of intercellular contacts, signaling pathways and gene expression characteristic for tissue in vivo. This paper presents the biology of three-dimensional cultures (spheroids), their applications in basic science and biotechnology and methods of spheroids formation.

  16. Medication-Related Osteonecrosis of the Jaw: Basic and Translational Science Updates.

    PubMed

    Allen, Matthew R

    2015-11-01

    In the late 1990s and the early 2000s, bisphosphonates had become the clinical pillar of excellence for treating metabolic bone disease, and thus their connection with osteonecrosis of the jaw (ONJ) caused significant concern. Over the past decade, progress has been made in understanding what is now referred to as medication-related ONJ (MRONJ), because of its connections to agents other than bisphosphonates, although in many respects the progress has been slow. This review highlights the key basic science and translational (animal) studies in the area of MRONJ and suggests areas of focus as the field moves into the next decade. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Back from basics: integration of science and practice in medical education.

    PubMed

    Bandiera, Glen; Kuper, Ayelet; Mylopoulos, Maria; Whitehead, Cynthia; Ruetalo, Mariela; Kulasegaram, Kulamakan; Woods, Nicole N

    2017-10-10

    In 1988, the Edinburgh Declaration challenged medical teachers, curriculum designers and leaders to make an organised effort to change medical education for the better. Among a series of recommendations was a call to integrate training in science and clinical practice across a breadth of clinical contexts. The aim was to create physicians who could serve the needs of all people and provide care in a multitude of contexts. In the years since, in the numerous efforts towards integration, new models of curricula have been proposed and implemented with varying levels of success. In this paper, we examine the evolution of curricular integration since the Edinburgh Declaration, and discuss theoretical advances and practical solutions. In doing so, we draw on recent consensus reports on the state of medical education, emblematic initiatives reported in the literature, and developments in education theory pertinent to the role of integrated curricula. Interest in integration persists despite 30 years of efforts to respond to the Edinburgh Declaration. We argue, however, that a critical shift has taken place with respect to the conception of integration, whereby empirical models support a view of integration as pertaining to both cognitive activity and curricular structure. In addition, we describe a broader definition of 'basic science' relevant to clinical practice that encompasses social and behavioural sciences, as well as knowledge derived from biomedical science. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

  18. Integration of Basic and Clinical Science Courses in US PharmD Programs.

    PubMed

    Islam, Mohammed A; Talukder, Rahmat M; Taheri, Reza; Blanchard, Nicholas

    2016-12-25

    Objective. To determine the current status of and faculty perceptions regarding integration of basic and clinical science courses in US pharmacy programs. Methods. A 25-item survey instrument was developed and distributed to 132 doctor of pharmacy (PharmD) programs. Survey data were analyzed using Mann-Whitney U test or Kruskal-Wallis test. Thematic analysis of text-based comments was performed using the constant comparison method. Results. One hundred twelve programs responded for a response rate of 85%. Seventy-eight (70%) offered integrated basic and clinical science courses. The types of integration included: full integration with merging disciplinary contents (n=25), coordinated delivery of disciplinary contents (n=50), and standalone courses with integrated laboratory (n=3). Faculty perceptions of course integration were positive. Themes that emerged from text-based comments included positive learning experiences as well as the challenges, opportunities, and skepticism associated with course integration. Conclusion. The results suggest wide variations in the design and implementation of integrated courses among US pharmacy programs. Faculty training and buy-in play a significant role in successful implementation of curricular integration.

  19. Integration of Basic and Clinical Science Courses in US PharmD Programs

    PubMed Central

    Talukder, Rahmat M.; Taheri, Reza; Blanchard, Nicholas

    2016-01-01

    Objective. To determine the current status of and faculty perceptions regarding integration of basic and clinical science courses in US pharmacy programs. Methods. A 25-item survey instrument was developed and distributed to 132 doctor of pharmacy (PharmD) programs. Survey data were analyzed using Mann-Whitney U test or Kruskal-Wallis test. Thematic analysis of text-based comments was performed using the constant comparison method. Results. One hundred twelve programs responded for a response rate of 85%. Seventy-eight (70%) offered integrated basic and clinical science courses. The types of integration included: full integration with merging disciplinary contents (n=25), coordinated delivery of disciplinary contents (n=50), and standalone courses with integrated laboratory (n=3). Faculty perceptions of course integration were positive. Themes that emerged from text-based comments included positive learning experiences as well as the challenges, opportunities, and skepticism associated with course integration. Conclusion. The results suggest wide variations in the design and implementation of integrated courses among US pharmacy programs. Faculty training and buy-in play a significant role in successful implementation of curricular integration. PMID:28179715

  20. A Team-based Assignment to Integrate Basic Science and Pharmacotherapeutic Principles for Anticancer Agents.

    PubMed

    Kurup, Sonali; Jungsuwadee, Paiboon; Sakharkar, Prashant

    2017-06-01

    Objective. To implement and evaluate an active-learning, team-based assignment centered on anticancer agents for the integration of basic science and pharmacotherapeutic principles. Methods. Student teams were assigned a specific anticancer agent and were expected to answer a series of questions on the written section of the assignment, followed by a presentation to the class. Each assignment was assessed using a grading rubric that was mapped to the 2013 CAPE educational outcomes. Student perceptions of the assignment were assessed using a short survey. Results. Student cohort performance on the assignment was in the B range (83%) with a mean of 33.2 out of 40. Using the grading rubric, the 12 student cohorts performed particularly well under professionalism (Domain 4.4) that focuses on personal and professional development from CAPE 2013 with means >4 on a 1-5 scale. Student impressions of the assignment suggested that students believed the assignment had a positive effect on their learning and should be continued. Conclusion. The assignment provided a focused review of basic science and pharmacotherapeutic principles and enabled integration of concepts relating to the therapeutic application of anticancer agents, and management of anticancer agent mediated adverse effects. The assignment could contribute toward preparing students for the evolving role of the pharmacist in the management of cancer.

  1. A Team-based Assignment to Integrate Basic Science and Pharmacotherapeutic Principles for Anticancer Agents

    PubMed Central

    Jungsuwadee, Paiboon; Sakharkar, Prashant

    2017-01-01

    Objective. To implement and evaluate an active-learning, team-based assignment centered on anticancer agents for the integration of basic science and pharmacotherapeutic principles. Methods. Student teams were assigned a specific anticancer agent and were expected to answer a series of questions on the written section of the assignment, followed by a presentation to the class. Each assignment was assessed using a grading rubric that was mapped to the 2013 CAPE educational outcomes. Student perceptions of the assignment were assessed using a short survey. Results. Student cohort performance on the assignment was in the B range (83%) with a mean of 33.2 out of 40. Using the grading rubric, the 12 student cohorts performed particularly well under professionalism (Domain 4.4) that focuses on personal and professional development from CAPE 2013 with means >4 on a 1-5 scale. Student impressions of the assignment suggested that students believed the assignment had a positive effect on their learning and should be continued. Conclusion. The assignment provided a focused review of basic science and pharmacotherapeutic principles and enabled integration of concepts relating to the therapeutic application of anticancer agents, and management of anticancer agent mediated adverse effects. The assignment could contribute toward preparing students for the evolving role of the pharmacist in the management of cancer. PMID:28720921

  2. Landscape of Innovation for Cardiovascular Pharmaceuticals: From Basic Science to New Molecular Entities.

    PubMed

    Beierlein, Jennifer M; McNamee, Laura M; Walsh, Michael J; Kaitin, Kenneth I; DiMasi, Joseph A; Ledley, Fred D

    2017-07-01

    This study examines the complete timelines of translational science for new cardiovascular therapeutics from the initiation of basic research leading to identification of new drug targets through clinical development and US Food and Drug Administration (FDA) approval of new molecular entities (NMEs) based on this research. This work extends previous studies by examining the association between the growth of research on drug targets and approval of NMEs associated with these targets. Drawing on research on innovation in other technology sectors, where technological maturity is an important determinant in the success or failure of new product development, an analytical model was used to characterize the growth of research related to the known targets for all 168 approved cardiovascular therapeutics. Categorizing and mapping the technological maturity of cardiovascular therapeutics reveal that (1) there has been a distinct transition from phenotypic to targeted methods for drug discovery, (2) the durations of clinical and regulatory processes were significantly influenced by changes in FDA practice, and (3) the longest phase of the translational process was the time required for technology to advance from initiation of research to a statistically defined established point of technology maturation (mean, 30.8 years). This work reveals a normative association between metrics of research maturation and approval of new cardiovascular therapeutics and suggests strategies for advancing translational science by accelerating basic and applied research and improving the synchrony between the maturation of this research and drug development initiatives. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

  3. An elective course on the basic and clinical sciences aspects of vitamins and minerals.

    PubMed

    Islam, Mohammed A

    2013-02-12

    Objective. To develop and implement an elective course on vitamins and minerals and their usefulness as dietary supplements. Design. A 2-credit-hour elective course designed to provide students with the most up-to-date basic and clinical science information on vitamins and minerals was developed and implemented in the doctor of pharmacy (PharmD) curriculum. In addition to classroom lectures, an active-learning component was incorporated in the course in the form of group discussion. Assessment. Student learning was demonstrated by examination scores. Performance on pre- and post-course surveys administered in 2011 demonstrated a significant increase in students' knowledge of the basic and clinical science aspects of vitamins and minerals, with average scores increasing from 61% to 86%. At the end of the semester, students completed a standard course evaluation. Conclusion. An elective course on vitamin and mineral supplements was well received by pharmacy students and helped them to acquire knowledge and competence in patient counseling regarding safe, appropriate, effective, and economical use of these products.

  4. An Elective Course on the Basic and Clinical Sciences Aspects of Vitamins and Minerals

    PubMed Central

    2013-01-01

    Objective. To develop and implement an elective course on vitamins and minerals and their usefulness as dietary supplements. Design. A 2-credit-hour elective course designed to provide students with the most up-to-date basic and clinical science information on vitamins and minerals was developed and implemented in the doctor of pharmacy (PharmD) curriculum. In addition to classroom lectures, an active-learning component was incorporated in the course in the form of group discussion. Assessment. Student learning was demonstrated by examination scores. Performance on pre- and post-course surveys administered in 2011 demonstrated a significant increase in students’ knowledge of the basic and clinical science aspects of vitamins and minerals, with average scores increasing from 61% to 86%. At the end of the semester, students completed a standard course evaluation. Conclusion. An elective course on vitamin and mineral supplements was well received by pharmacy students and helped them to acquire knowledge and competence in patient counseling regarding safe, appropriate, effective, and economical use of these products. PMID:23463149

  5. Establishing a successful basic science research program in colon and rectal surgery.

    PubMed

    Leeds, Ira; Wick, Elizabeth C

    2014-06-01

    Although at first glance, the surgeon-scientist appears to be a rare breed in today's clinical revenue-driven world, with careful planning and mentorship this is still a vibrant career path. If one is considering this avenue, it is important to seize even small opportunities to pursue laboratory work during training-summers in college and medical school, rotation blocks, and dedicated time in the middle of residency. Publications and small grants during these times will lay the ground work for future success. When considering a faculty position, it is essential to identify a mentorship environment that has a track record for success-either in the department of surgery or anywhere in the university. Ensuring adequate support from the department of surgery chair and division leader is essential. Basic science careers take years for the return in investment to be manifested! Also critical is to secure extramural funding early in the faculty stint-first foundation grants and then National Institutes of Health-mentored scientist funding. Surgeons provide a unique perspective in basic science work and it is critical that we continue to support young surgeons in this career path.

  6. Establishing a Successful Basic Science Research Program in Colon and Rectal Surgery

    PubMed Central

    Leeds, Ira; Wick, Elizabeth C.

    2014-01-01

    Although at first glance, the surgeon-scientist appears to be a rare breed in today's clinical revenue-driven world, with careful planning and mentorship this is still a vibrant career path. If one is considering this avenue, it is important to seize even small opportunities to pursue laboratory work during training—summers in college and medical school, rotation blocks, and dedicated time in the middle of residency. Publications and small grants during these times will lay the ground work for future success. When considering a faculty position, it is essential to identify a mentorship environment that has a track record for success—either in the department of surgery or anywhere in the university. Ensuring adequate support from the department of surgery chair and division leader is essential. Basic science careers take years for the return in investment to be manifested! Also critical is to secure extramural funding early in the faculty stint—first foundation grants and then National Institutes of Health–mentored scientist funding. Surgeons provide a unique perspective in basic science work and it is critical that we continue to support young surgeons in this career path. PMID:25067919

  7. What's hot, what's new in basic science: report from the American Transplant Congress 2015.

    PubMed

    Heeger, P S

    2015-11-01

    Research reports presented at the American Transplant Congress 2015 provided an array of basic science findings of relevance to the transplant community. Among key themes is the concept that ischemia-reperfusion injury and early posttransplantation inflammation is linked to adaptive alloimmunity and transplant injury. Molecular and cellular mechanisms contributing to these interactions were highlighted. The relevance of understanding how blocking costimulation, including CD40/CD154 interactions, affects various aspects of the alloimmune response was enhanced by the description of preclinical studies demonstrating efficacy of a unique, blocking anti-CD40 monoclonal antibody that could potentially be used in humans. The identification of mechanisms underlying interactions among T cell subsets and B cells, including follicular helper T cells, regulatory T cells, effector B cells, and regulatory B cells, provides multiple previously unrecognized targets for future therapeutic interventions. Additional reports of interest include novel insights into effects of the gut microbiome on graft survival and the ability to differentiate insulin-secreting, islet-like cells from induced pluripotent stem cells. Overall, the reported basic science findings from American Transplant Congress 2015 add to the fundamental understanding of innate and adaptive alloimmunity and provide novel and testable hypotheses that have the potential to be translated into improved clinical care of transplant patients. © Copyright 2015 The American Society of Transplantation and the American Society of Transplant Surgeons.

  8. The Impact of Emotion on Learners' Application of Basic Science Principles to Novel Problems.

    PubMed

    McConnell, Meghan M; Monteiro, Sandra; Pottruff, Molly M; Neville, Alan; Norman, Geoff R; Eva, Kevin W; Kulasegaram, Kulamakan

    2016-11-01

    Training to become a physician is an emotionally laden experience. Research in cognitive psychology indicates that emotions can influence learning and performance, but the materials used in such research (e.g., word lists) rarely reflect the complexity of material presented in medical school. The present study examined whether emotions influence learning of basic science principles. Fifty-five undergraduate psychology students were randomly assigned to write about positive, negative, or neutral life events for nine minutes. Participants were then taught three physiological concepts, each in the context of a single organ system. Testing consisted of 13 clinical cases, 7 presented with the same concept/organ system pairing used during training ("near transfer") and 6 with novel pairings ("far transfer"). Testing was repeated after one week with 13 additional cases. Forty-nine students provided complete data. Higher test scores were found when the concept/organ system pairing was held constant (near transfer = 51% correct vs. far = 33%; P < .001). Emotion condition influenced participants' overall performance, with individuals in the neutral condition (50.1%) performing better than those in the positive (38.2%, P < .05) and negative (37.7%, P < .001) emotion conditions. These data suggest that regardless of whether the emotion is positive or negative, mild affective states can impair learning of basic science concepts by novices. Demands on working memory and subsequent cognitive load provide a potential explanation. Future work will examine the extent to which these findings generalize to medical trainees.

  9. Making Basic Science Studies in Glaucoma More Clinically Relevant: The Need for a Consensus.

    PubMed

    Toris, Carol B; Gelfman, Claire; Whitlock, Andy; Sponsel, William E; Rowe-Rendleman, Cheryl L

    2017-09-01

    Glaucoma is a chronic, progressive, and debilitating optic neuropathy that causes retinal damage and visual defects. The pathophysiologic mechanisms of glaucoma remain ill-defined, and there is an indisputable need for contributions from basic science researchers in defining pathways for translational research. However, glaucoma researchers today face significant challenges due to the lack of a map of integrated pathways from bench to bedside and the lack of consensus statements to guide in choosing the right research questions, techniques, and model systems. Here, we present the case for the development of such maps and consensus statements, which are critical for faster development of the most efficacious glaucoma therapy. We underscore that interrogating the preclinical path of both successful and unsuccessful clinical programs is essential to defining future research. One aspect of this is evaluation of available preclinical research tools. To begin this process, we highlight the utility of currently available animal models for glaucoma and emphasize that there is a particular need for models of glaucoma with normal intraocular pressure. In addition, we outline a series of discoveries from cell-based, animal, and translational research that begin to reveal a map of glaucoma from cell biology to physiology to disease pathology. Completion of these maps requires input and consensus from the global glaucoma research community. This article sets the stage by outlining various approaches to such a consensus. Together, these efforts will help accelerate basic science research, leading to discoveries with significant clinical impact for people with glaucoma.

  10. Restructuring a basic science course for core competencies: an example from anatomy teaching.

    PubMed

    Gregory, Jeremy K; Lachman, Nirusha; Camp, Christopher L; Chen, Laura P; Pawlina, Wojciech

    2009-09-01

    Medical schools revise their curricula in order to develop physicians best skilled to serve the public's needs. To ensure a smooth transition to residency programs, undergraduate medical education is often driven by the six core competencies endorsed by the Accreditation Council for Graduate Medical Education (ACGME): patient care, medical knowledge, practice-based learning, interpersonal skills, professionalism, and systems-based practice. Recent curricular redesign at Mayo Medical School provided an opportunity to restructure anatomy education and integrate radiology with first-year gross and developmental anatomy. The resulting 6-week (120-contact-hour) human structure block provides students with opportunities to learn gross anatomy through dissection, radiologic imaging, and embryologic correlation. We report more than 20 educational interventions from the human structure block that may serve as a model for incorporating the ACGME core competencies into basic science and early medical education. The block emphasizes clinically-oriented anatomy, invites self- and peer-evaluation, provides daily formative feedback through an audience response system, and employs team-based learning. The course includes didactic briefing sessions and roles for students as teachers, leaders, and collaborators. Third-year medical students serve as teaching assistants. With its clinical focus and competency-based design, the human structure block connects basic science with best-practice clinical medicine.

  11. An overview of digital spectrometers for MR imaging. Instrumentation Subcommittee of the SMRI Basic Science Council.

    PubMed

    Holland, G N; MacFall, J R

    1992-01-01

    Most magnetic resonance (MR) imaging systems were originally designed with analog spectrometers, since that was the "state of the art" in the late 1970s, when they were developed. Advances in technology have allowed the design of radio-frequency electronics with a much larger percentage of digital components while the cost of such components has decreased. This has given manufacturers the incentive to develop new spectrometers that incorporate these electronics for cost reduction and potentially better performance. Upgrades and new models of MR units have become available with these so-called "digital spectrometers." Because of the interest in the new systems, the Instrumentation Subcommittee of the Basic Science Council of the Society for Magnetic Resonance Imaging has produced this report to review the basic features of analog and digital spectrometers to help the MR imaging community better understand the similarities and differences of these systems. Some details of actual commercial implementations were left out to focus on the basic features. Regardless, the authors hope they have provided a readable introduction to this important topic.

  12. Science and the Energy Security Challenge: The Example of Solid-State Lighting

    ScienceCinema

    Philips, Julia [Sandia

    2016-07-12

    Securing a viable, carbon neutral energy future for humankind will require an effort of gargantuan proportions. As outlined clearly in a series of workshops sponsored by the DOE Office of Basic Energy Sciences (http://www.sc.doe.gov/bes/reports/list.html), fundamental advances in scientific understanding are needed to broadly implement many of the technologies that are held out as promising options to meet future energy needs, ranging from solar energy, to nuclear energy, to approaches to clean combustion. Using solid state lighting based on inorganic materials as an example, I will discuss some recent results and new directions, emphasizing the multidisciplinary, team nature of the endeavor. I will also offer some thoughts about how to encourage translation of the science into attractive, widely available products – a significant challenge that cannot be ignored. This case study offers insight into approaches that are likely to be beneficial for addressing other aspects of the energy security challenge.

  13. Assessment of knowledge and perceptions toward generic medicines among basic science undergraduate medical students at Aruba

    PubMed Central

    Shankar, P. Ravi; Herz, Burton L.; Dubey, Arun K.; Hassali, Mohamed A.

    2016-01-01

    Objective: Use of generic medicines is important to reduce rising health-care costs. Proper knowledge and perception of medical students and doctors toward generic medicines are important. Xavier University School of Medicine in Aruba admits students from the United States, Canada, and other countries to the undergraduate medical (MD) program. The present study was conducted to study the knowledge and perception about generic medicines among basic science MD students. Materials and Methods: The cross-sectional study was conducted among first to fifth semester students during February 2015. A previously developed instrument was used. Basic demographic information was collected. Respondent’s agreement with a set of statements was noted using a Likert-type scale. The calculated total score was compared among subgroups of respondents. One sample Kolmogorov–Smirnov test was used to study the normality of distribution, Independent samples t-test to compare the total score for dichotomous variables, and analysis of variance for others were used for statistical analysis. Results: Fifty-six of the 85 students (65.8%) participated. Around 55% of respondents were between 20 and 25 years of age and of American nationality. Only three respondents (5.3%) provided the correct value of the regulatory bioequivalence limits. The mean total score was 43.41 (maximum 60). There was no significant difference in scores among subgroups. Conclusions: There was a significant knowledge gap with regard to the regulatory bioequivalence limits for generic medicines. Respondents’ level of knowledge about other aspects of generic medicines was good but could be improved. Studies among clinical students in the institution and in other Caribbean medical schools are required. Deficiencies were noted and we have strengthened learning about generic medicines during the basic science years. PMID:28031604

  14. Assessment of knowledge and perceptions toward generic medicines among basic science undergraduate medical students at Aruba.

    PubMed

    Shankar, P Ravi; Herz, Burton L; Dubey, Arun K; Hassali, Mohamed A

    2016-10-01

    Use of generic medicines is important to reduce rising health-care costs. Proper knowledge and perception of medical students and doctors toward generic medicines are important. Xavier University School of Medicine in Aruba admits students from the United States, Canada, and other countries to the undergraduate medical (MD) program. The present study was conducted to study the knowledge and perception about generic medicines among basic science MD students. The cross-sectional study was conducted among first to fifth semester students during February 2015. A previously developed instrument was used. Basic demographic information was collected. Respondent's agreement with a set of statements was noted using a Likert-type scale. The calculated total score was compared among subgroups of respondents. One sample Kolmogorov-Smirnov test was used to study the normality of distribution, Independent samples t-test to compare the total score for dichotomous variables, and analysis of variance for others were used for statistical analysis. Fifty-six of the 85 students (65.8%) participated. Around 55% of respondents were between 20 and 25 years of age and of American nationality. Only three respondents (5.3%) provided the correct value of the regulatory bioequivalence limits. The mean total score was 43.41 (maximum 60). There was no significant difference in scores among subgroups. There was a significant knowledge gap with regard to the regulatory bioequivalence limits for generic medicines. Respondents' level of knowledge about other aspects of generic medicines was good but could be improved. Studies among clinical students in the institution and in other Caribbean medical schools are required. Deficiencies were noted and we have strengthened learning about generic medicines during the basic science years.

  15. International cooperation in basic space science, Western Asian countries and the world

    NASA Astrophysics Data System (ADS)

    de Morais Mendonca Teles, Antonio

    The world will never better develop and attain a global peace state, if it does not exist a world-wide cooperation, union of interests among all countries on planet Earth, respecting and understanding each other culture differences. So, if the countries interested in space science want to create or better develop this field, they need to firstly construct peace states and social cooperation, while scientific and technological cooperation will develop -among them. Here in this paper, under the principles in the United Nations (UN)' Agenda 21 (UN UNCED, 1992), I propose four points that can lead to a practical and solid international cooperation in basic aerospace science and technology, based on ground studies, with sustainable space programs in countries with social necessities, and to the construction of an avenue of peace states in those areas and in the world, 1) The creation of LINKS among the "developing" countries, among the "developed" ones and between them -with scientists, engineers, educators and administrative personnel. This can catalyze a self-sustainable scientific and technological production in the "developing" countries. Financial matters could be done through the World Bank in coopera-tion with UNESCO. 2) The administration of this difficult enterprise of international coopera-tion. With the increasing complexity of relationships among the aerospace-interested countries, it will be necessary the creation of a center capable to serve as an INTERNATIONAL CO-ORDINATOR CENTER FOR AEROSPACE ACTIVITIES. 3) CULTURE: in Western Asian countries there is a cultural habit that when somebody gives something valuable to a person, this person should give something back. Thus, the Western Asian countries receiving infor-mation on basic aerospace science and technology from the "developed" ones, those countries would probably feel they should give something in return. Western Asian countries could trans-mit their costumes, thinking ways, habits, persons' worries

  16. Obstacles of Implementing the Science Curricula of the Basic Stage as Perceived by the Teachers in a Jordanian Town

    ERIC Educational Resources Information Center

    Ayasra, Ahmad

    2015-01-01

    This study aimed to investigate obstacles that prevent implementation of science curriculum which was developed within the Education Reform for the Knowledge Economy project (ErfKE). To achieve this, a purposeful sample consisted of four teachers of science for the basic stage in the town located in the north of Jordan in the first semester of the…

  17. The Views of Science Pre-Service Teachers about the Usage of Basic Information Technologies (BIT) in Education and Instruction

    ERIC Educational Resources Information Center

    Çetin, Oguz

    2016-01-01

    In this study aiming to present a description based on science pre-service teachers' views related to use of Basic Information Technologies (BIT) in education and training, an interview is carried out with 21 pre-service science teachers who study in different classes in Faculty of Education, Nigde University. For this aim, improved interview form…

  18. Rare isotope accelerator project in Korea and its application to high energy density sciences

    NASA Astrophysics Data System (ADS)

    Chung, M.; Chung, Y. S.; Kim, S. K.; Lee, B. J.; Hoffmann, D. H. H.

    2014-01-01

    As a national science project, the Korean government has recently established the Institute for Basic Science (IBS) with the goal of conducting world-class research in basic sciences. One of the core facilities for the IBS will be the rare isotope accelerator which can produce high-intensity rare isotope beams to investigate the fundamental properties of nature, and also to support a broad research program in material sciences, medical and biosciences, and future nuclear energy technologies. The construction of the accelerator is scheduled to be completed by approximately 2017. The design of the accelerator complex is optimized to deliver high average beam current on targets, and to maximize the production of rare isotope beams through the simultaneous use of Isotope Separation On-Line (ISOL) and In-Flight Fragmentation (IFF) methods. The proposed accelerator is, however, not optimal for high energy density science, which usually requires very high peak currents on the target. In this study, we present possible beam-plasma experiments that can be done within the scope of the current accelerator design, and we also investigate possible future extension paths that may enable high energy density science with intense pulsed heavy ion beams.

  19. Evaluation of Students' Energy Conception in Environmental Science

    ERIC Educational Resources Information Center

    Park, Mihwa; Johnson, Joseph A.

    2016-01-01

    While significant research has been conducted on students' conceptions of energy, alternative conceptions of energy have not been actively explored in the area of environmental science. The purpose of this study is to examine students' alternative conceptions in the environmental science discipline through the analysis of responses of first year…

  20. How neuroscience is taught to North American dental students: results of the Basic Science Survey Series.

    PubMed

    Gould, Douglas J; Clarkson, Mackenzie J; Hutchins, Bob; Lambert, H Wayne

    2014-03-01

    The purpose of this study was to determine how North American dental students are taught neuroscience during their preclinical dental education. This survey represents one part of a larger research project, the Basic Science Survey Series for Dentistry, which covers all of the biomedical science coursework required of preclinical students in North American dental schools. Members of the Section on Anatomical Sciences of the American Dental Education Association assembled, distributed, and analyzed the neuroscience survey, which had a 98.5 percent response from course directors of the sixty-seven North American dental schools. The eighteen-item instrument collected demographic data on the course directors, information on the content in each course, and information on how neuroscience content is presented. Findings indicate that 1) most neuroscience instruction is conducted by non-dental school faculty members; 2) large content variability exists between programs; and 3) an increase in didactic instruction, integrated curricula, and use of computer-aided instruction is occurring. It is anticipated that the information derived from the survey will help guide neuroscience curricula in dental schools and aid in identifying appropriate content.

  1. Embryology and histology education in North American dental schools: the Basic Science Survey Series.

    PubMed

    Burk, Dorothy T; Lee, Lisa M J; Lambert, H Wayne

    2013-06-01

    As part of the Basic Science Survey Series (BSSS) for Dentistry, members of the American Dental Education Association (ADEA) Anatomical Sciences Section surveyed faculty members teaching embryology and histology courses at North American dental schools. The survey was designed to assess, among other things, curriculum content, utilization of laboratories, use of computer-assisted instruction (CAI), and recent curricular changes. Responses were received from fifty-nine (88.1 percent) of the sixty-seven U.S. and Canadian dental schools. Findings suggest the following: 1) a trend toward combining courses is evident, though the integration was predominantly discipline-based; 2) embryology is rarely taught as a stand-alone course, as content is often covered in gross anatomy, oral histology, and/or in an integrated curriculum; 3) the number of contact hours in histology is decreasing; 4) a trend toward reduction in formal laboratory sessions, particularly in embryology, is ongoing; and 5) use of CAI tools, including virtual microscopy, in both embryology and histology has increased. Additionally, embryology and histology content topic emphasis is identified within this study. Data, derived from this study, may be useful to new instructors, curriculum and test construction committees, and colleagues in the anatomical sciences, especially when determining a foundational knowledge base.

  2. The Divergent Thinking of Basic Skills of Sciences Process Skills of Life Aspects on Natural Sciences Subject in Indonesian Elementary School Students

    ERIC Educational Resources Information Center

    Subali, Bambang; Paidi; Mariyam, Siti

    2016-01-01

    This research aims at measuring the divergent thinking of basic skills of science process skills (SPS) of life aspects in Natural Sciences subjects on Elementary School. The test instruments used in this research have been standardized through the development of instruments. In this case, the tests were tried out to 3070 students. The results of…

  3. The Cognitive Outcome in the Physical Games at the College of Students of the Basic Science in the World Islamic Sciences and Education University

    ERIC Educational Resources Information Center

    Salameh, Ibrahim A. M.; Al-Maharmeh, Yaseen A. M.; Oudat, Mo'een A.

    2013-01-01

    The study aimed at reconnoitering the cognitive outcome in the physical games at students of the college of basic science in the World Islamic Science and Education University. The descriptive method was employed, where the sample was randomly chosen, and amounted to (16) students (males & females) from the faculty. The sample discussed five…

  4. The Divergent Thinking of Basic Skills of Sciences Process Skills of Life Aspects on Natural Sciences Subject in Indonesian Elementary School Students

    ERIC Educational Resources Information Center

    Subali, Bambang; Paidi; Mariyam, Siti

    2016-01-01

    This research aims at measuring the divergent thinking of basic skills of science process skills (SPS) of life aspects in Natural Sciences subjects on Elementary School. The test instruments used in this research have been standardized through the development of instruments. In this case, the tests were tried out to 3070 students. The results of…

  5. There was less self-critique among basic than in clinical science articles in three rheumatology journals.

    PubMed

    Yazici, Hasan; Gogus, Feride; Esen, Fehim; Yazici, Yusuf

    2014-06-01

    There is concern that self-critique with authors acknowledging limitations of their work is not given due importance in scientific articles. We had the impression that this was more true for articles in basic compared with clinical science. We thus surveyed for the presence of self-critique in the discussion sections of the original articles in three rheumatology journals with attention to differences between the basic and the clinical science articles. The discussion sections of the original articles in January, May, and September 2012 issues of Annals of the Rheumatic Diseases, Arthritis and Rheumatism, and Rheumatology (Oxford) were surveyed (n = 223) after classifying each article as mainly related to clinical or basic science. The discussion sections were electronically scanned by two observers for the presence of the root word "limit" or its derivatives who also read each discussion section for the presence of any limitations otherwise voiced. A limitation discussion in any form was present in only 19 (20.2%) or 29 (30.1%) of 94 basic science vs. 95 (73.6%) or 107 (82.3%) of 129 clinical science articles (P < 0.0001 for either observer). Self-critique, especially lacking in basic science articles, should be given due attention. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Facing Our Energy Challenges in a New Era of Science (2011 EFRC Forum)

    ScienceCinema

    Dehmer, Patricia M. (Deputy Director for Science Programs at DOE)

    2016-07-12

    Patricia Dehmer, Deputy Director for Science Programs at DOE, opened the May 26, 2011 EFRC Forum session, 'Global Perspectives on Frontiers in Energy Research,' with the talk, 'Facing Our Energy Challenges in a New Era of Science.' In her presentation, Dr. Dehmer gave a tutorial on the energy challenges facing our Nation and showed how the DOE research portfolio addresses those issues. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss 'Science for our Nation's Energy Future.' In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  7. Energy and Agriculture. A Basic Core Curriculum for Teaching Energy to Vocational Agriculture Students.

    ERIC Educational Resources Information Center

    Albracht, James; French, Byron

    This core curriculum contains five units of material for teaching energy to vocational agriculture students. Energy uses and the benefits of energy conservation are covered in a unit on the impact of energy on agriculture. Discussed next are tractor performance and Nebraska tractor test data for selecting and evaluating tractors for maximum fuel…

  8. Energy and Agriculture. A Basic Core Curriculum for Teaching Energy to Vocational Agriculture Students.

    ERIC Educational Resources Information Center

    Albracht, James; French, Byron

    This core curriculum contains five units of material for teaching energy to vocational agriculture students. Energy uses and the benefits of energy conservation are covered in a unit on the impact of energy on agriculture. Discussed next are tractor performance and Nebraska tractor test data for selecting and evaluating tractors for maximum fuel…

  9. Nuffield Secondary Science, Theme 4, Harnessing Energy.

    ERIC Educational Resources Information Center

    Howard, Edgar

    Nuffield Secondary Science is a set of tested materials from which teachers can prepare courses for students in grades 9-11 (approximately) who do not intend to major in science. The materials are designed for British secondary schools but are adaptable to other countries. The Teachers' Guide to the entire set of Themes is described in SE 015 440…

  10. Understanding Engagement: Science Demonstrations and Emotional Energy

    ERIC Educational Resources Information Center

    Milne, Catherine; Otieno, Tracey

    2007-01-01

    Although beloved of some chemists and physicists, science demonstrations have been criticized for stifling inquiry and assisting teachers to maintain a power differential between themselves and students in the classroom. This interpretive study reports the unexpected positive learning outcomes for urban science students in two chemistry classes…

  11. Understanding Engagement: Science Demonstrations and Emotional Energy

    ERIC Educational Resources Information Center

    Milne, Catherine; Otieno, Tracey

    2007-01-01

    Although beloved of some chemists and physicists, science demonstrations have been criticized for stifling inquiry and assisting teachers to maintain a power differential between themselves and students in the classroom. This interpretive study reports the unexpected positive learning outcomes for urban science students in two chemistry classes…

  12. Nuffield Secondary Science, Theme 4, Harnessing Energy.

    ERIC Educational Resources Information Center

    Howard, Edgar

    Nuffield Secondary Science is a set of tested materials from which teachers can prepare courses for students in grades 9-11 (approximately) who do not intend to major in science. The materials are designed for British secondary schools but are adaptable to other countries. The Teachers' Guide to the entire set of Themes is described in SE 015 440…

  13. Role of basic biological sciences in clinical orthodontics: a case series.

    PubMed

    Davidovitch, Ze'ev; Krishnan, Vinod

    2009-02-01

    Orthodontic therapy is based on interaction between mechanics and biology. Basic biologic research aims at developing a better understanding of the mechanism of transformation of mechanical energy into biologic reactions, and exposing the reasons for iatrogenic tissue damage in orthodontics. Previous research has shown that inflammation is a major part of the biologic response to orthodontic forces. In inflammation, signal molecules that originate in remote diseased organs can reach strained paradental tissues and exacerbate the inflammatory process, leading to tissue damage. Our case series includes 3 patients, each having had systemic diseases and malocclusion. One had diabetes mellitus, Hashimoto's thyroiditis, and depression. Concern about the possible effect of these conditions on the well-being of the teeth and their surrounding tissues compelled the orthodontist to choose not to treat this patient. The other 2 patients had allergies, and 1 also had bronchial asthma and bruises. Although these conditions are thought to be risk factors for root resorption, these patients received orthodontic treatment for 2 and 3.5 years, respectively. At the end of treatment, both had excessive root resorption of many teeth. In 1 patient, this damage led to the loss of most maxillary teeth. Basic research should continue to address questions related to the biologic mechanisms of tooth movement on tissue, cellular, and molecular levels. Moreover, this research should continue to identify risk factors that might jeopardize the longevity of treated teeth. Such basic research should promote the development of new tissue-friendly and patient-friendly therapeutic methods.

  14. Cartilage repair: synthetics and scaffolds: basic science, surgical techniques, and clinical outcomes.

    PubMed

    Kerker, Jordan T; Leo, Andrew J; Sgaglione, Nicholas A

    2008-12-01

    Symptomatic articular cartilage lesions have gained attention and clinical interest in recent years and can be difficult to treat. Historically, various biologic surgical treatment options have yielded inconsistent results because of the inferior biomechanical properties associated with a variable healing response. Improving technology and surgical advances has generated considerable research in cartilage resurfacing and optimizing hyaline tissue restoration. Biologic innovation and tissue engineering in cartilage repair have used matrix scaffolds, autologous and allogenic chondrocytes, cartilage grafts, growth factors, stem cells, and genetic engineering. Numerous evolving technologies and surgical approaches have been introduced into the clinical setting. This review will discuss the basic science, surgical techniques, and clinical outcomes of novel synthetic materials and scaffolds for articular cartilage repair.

  15. [Evolution of the number of authors in clinical and basic science journals in the Spanish language].

    PubMed

    Soteras, F; Blanco, J R; García Pineda, A F; Rupérez, H; Córdova, A; Escanero, J F

    1990-01-01

    The number of signing authors in Revista Clínica Española. Revista Española de Fisiología and Revista Española de Oncología have been analyzed from their first to the last received issue. The results obtained show an increasing number of authors in all journals specially during the 70s. The results also point out a relative decrease in the number of authors in basic sciences in relation to clinical publications. The increase in the number of authors in The Revista Española de Oncología has started somewhat later than the others. The environmental and professional stress as well as the interrelations between different hospital members have been suggested, amongst others, as the possible cause of these events.

  16. Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy

    PubMed Central

    Kim, Joyce H.; Dougherty, Patrick M.; Abdi, Salahadin

    2017-01-01

    Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting toxicity of several chemotherapeutics used in the treatment of all the most common malignancies. There are several defined mechanisms of nerve damage that take place along different areas of the peripheral and the central nervous system. Treatment is based on symptom management and there are several classes of medications found to be efficacious in the treatment of neuropathic pain. Neuropathic pain that persists despite appropriate pharmacotherapy may respond to interventional procedures that span a range of invasiveness. The purpose of this review article is to examine the basic science of neuropathy and currently available treatment options in the context of chemotherapy induced peripheral neuropathy. PMID:25584767

  17. A prescription that addresses the decline of basic science education in medical school.

    PubMed

    Miller, Daniel; Thornton, Christina S; Keough, Michael B; Roberts, Jodie I; Yipp, Bryan; Hollenberg, Morley; Bau, Jason T; Peplowski, Michael A; Beck, Paul L

    2014-10-04

    Over 30 years ago a cry rang out through the proverbial halls of academia; "The clinician scientist is an endangered species." These prophetic words have been reverberated in the ears of every specialty and every general medical organization in deafening tones. Why is the role of the clinician scientist or clinician investigator so important that this phrase has been repeated subsequently in medical and educational journals? Simply put, the clinician scientist bridges the ravine between the ever-growing mountain of scientific knowledge and the demanding patient centered clinical care. Here, we describe the current educational model established by the University of Calgary, Leaders in Medicine Program. Our program seeks to train future physicians and clinician scientists by incorporating training in basic science, translational and clinical research with clinical and medical education in a longitudinal program to students of traditional MD/PhD, MD/MSc or MD/MBA stream as well as interested Doctor of Medicine students.

  18. Does teacher thinking match teaching practice? A study of basic science teachers.

    PubMed

    Laksov, Klara B; Nikkola, Matti; Lonka, Kirsti

    2008-02-01

    To obtain an understanding of basic science medical teachers' conceptions of learning and their ideas for facilitation of learning. Teaching staff at a biomedical centre (n = 62) were asked to describe their definitions of learning, their suggestions for how to solve an applied educational problem and their intended activities when teaching students. The research was carried out using a questionnaire consisting of open-ended and fixed-choice questions. Although 1 in 4 teachers endorsed constructivist conceptions of learning, only 1 in 8 actually reported using activating teaching strategies. Conceptions of learning did not co-vary with teaching practice. The assumption that conceptions of learning and teaching practice are aligned was challenged. The current questionnaire could be used as an intervention tool for educational development to map whether or not there is a match between teachers' conceptions and their practice.

  19. Role of Basic Science in the Development of New Medicines: Examples from the Eicosanoid Field

    PubMed Central

    Samuelsson, Bengt

    2012-01-01

    The role of basic science in the development of health care has received more and more attention. In my own area of research involving the so-called eicosanoids, there are many examples of how studies of structure and function of small molecules, as well as proteins and genes, have led to new therapeutic agents for treatment of a variety of diseases. In most of the cases, the discoveries have resulted in the recognition of novel therapeutic targets amenable to modulation by small molecules. However, there are also examples in which the molecular mechanisms of actions of drugs, discovered by phenotypic screening, have been elucidated. The majority of the examples in this article consist of approved drugs; however, in some cases, ongoing developments of potential therapeutics are cited. PMID:22318727

  20. The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder.

    PubMed

    Suzuki, Tadashi

    2015-01-01

    Peptide:N-glycanase (PNGase) is a de-N-glycosylating enzyme that cleaves intact N-glycans from glycoproteins/glycopeptides. The activity of the cytoplasmic PNGase in several mammalian-derived cultured cells was first reported in 1993, and 7 years later, the gene encoding the enzyme was identified in budding yeast. Although the gene-PNG1 in budding yeast and NGLY1/Ngly1 in mammalian cells-appears to be well conserved throughout eukaryotes, the biological significance of this enzyme has remained elusive until recently. However, discovery of a human genetic disorder involving the NGLY1 gene clearly indicates that this enzyme plays a critical role in human biology. This review summarizes the research history of cytoplasmic PNGase. The importance of curiosity-driven, pure 'basic science' will also be discussed. © The Authors 2014. Published by Oxford University Press on behalf of the Japanese Biochemical Society. All rights reserved.

  1. Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences.

    PubMed

    Shrestha, Badri Man

    2017-02-01

    Tacrolimus, a calcineurin inhibitor, has been the cornerstone of immunosuppressive regimens in renal transplant over 2 decades. This has significantly improved the outcomes of renal transplant, including reduction of acute rejection episodes, improvement of renal function and graft survival, and reduction of some of the adverse effects associated with cyclosporine. However, use of tacrolimus is associated with a number of undesirable effects, such as nephrotoxicity, posttransplant diabetes mellitus, neurotoxicity, and cosmetic and electrolyte disturbances. To alleviate these effects, several strategies have been adopted to minimize or eliminate tacrolimus from maintenance regimens of immunosuppression, with some success. This review focuses on advancements in the understanding of the basic science related to tacrolimus and the clinical evidences that have examined the efficacy and safety of tacrolimus in renal transplant over the past 2 decades and highlights the future directions.

  2. The role of cardiac PET in translating basic science into the clinical arena.

    PubMed

    Bravo, Paco E; Bengel, Frank M

    2011-08-01

    Non-invasive imaging has become fundamental in translating findings from basic science research into clinical applications. In this aspect, positron-emission tomography (PET) offers important advantages over other common imaging modalities like single-photon emission computed tomography, computed tomography, and magnetic resonance imaging (MRI), since PET provides superior detection sensitivity in the evaluation of different cardiovascular targets and pathways at the cellular and subcellular level, and because it is a well-established technique for absolute image quantification. The development and the introduction of dedicated small animal PET systems have greatly facilitated and contributed to advancements in the translation of novel radio-labeled compounds from experimental to clinical practice. The scope of the present article is to review the most relevant and successful PET applications in cardiovascular translational research.

  3. Regenerative dentistry: translating advancements in basic science research to the dental practice.

    PubMed

    Garcia-Godoy, Franklin; Murray, Peter

    2010-01-01

    Scientific advances in the creation of restorative biomaterials, in vitro cell culture technology, tissue engineering, molecular biology and the human genome project provide the basis for the introduction of new technologies into dentistry. This review provides an assessment of how tissue engineering, stem cell, genetic transfer, biomaterial and growth factor therapies can be integrated into clinical dental therapies to restore and regenerate oral tissues. In parallel to the creation of a new field in general medicine called "regenerative medicine," we call this field "regenerative dentistry." While the problems of introducing regenerative therapies are substantial, the potential benefits to patients and the profession are equally ground-breaking. In this review, we outline a few areas of interest for the future of oral and dental medicine in which advancements in basic science have already been adapted to fit the goals of 21st century dentistry.

  4. A brief history of geospatial science in the Department of Energy

    SciTech Connect

    Bhaduri, Budhendra L

    2007-01-01

    The U.S. Department of Energy (DOE) has a rich history of significant contributions to geospatial science spanning the past four decades. In the early years, work focused on basic research, such as development of algorithms for processing geographic data and early use of LANDSAT imagery. The emphasis shifted in the mid-1970s to development of geographic information system (GIS) applications to support programs such as the National Uranium Resource Evaluation (NURE), and later to issue-oriented GIS applications supporting programs such as environmental restoration and management (mid-1980s through present). Throughout this period, the DOE national laboratories represented a strong chorus of voices advocating the importance of geospatial science and technology in the decades to come. The establishment of a Geospatial Science Program by the DOE Office of the Chief Information Officer in 2005 reflects the continued potential of geospatial science to enhance DOE's science, projects, and operations, as is well demonstrated by historical analysis.

  5. Translating Basic Behavioral and Social Science Research to Clinical Application: The EVOLVE Mixed Methods Approach

    PubMed Central

    Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

    2012-01-01

    Objective To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in three high-risk clinical populations. Our theoretically-derived intervention comprised a combination of positive affect and self-affirmation (PA/SA) which we applied to three clinical chronic disease populations. Methods We employed a sequential mixed methods model (EVOLVE) to design and test the PA/SA intervention in order to increase physical activity in people with coronary artery disease (post-percutaneous coronary intervention [PCI]) or asthma (ASM), and to improve medication adherence in African Americans with hypertension (HTN). In an initial qualitative phase, we explored participant values and beliefs. We next pilot tested and refined the intervention, and then conducted three randomized controlled trials (RCTs) with parallel study design. Participants were randomized to combined PA/SA vs. an informational control (IC) and followed bimonthly for 12 months, assessing for health behaviors and interval medical events. Results Over 4.5 years, we enrolled 1,056 participants. Changes were sequentially made to the intervention during the qualitative and pilot phases. The three RCTs enrolled 242 PCI, 258 ASM and 256 HTN participants (n=756). Overall, 45.1% of PA/SA participants versus 33.6% of IC participants achieved successful behavior change (p=0.001). In multivariate analysis PA/SA intervention remained a significant predictor of achieving behavior change (p<0.002, OR=1.66, 95% CI 1.22–2.27), controlling for baseline negative affect, comorbidity, gender, race/ethnicity, medical events, smoking and age. Conclusions The EVOLVE method is a means by which basic behavioral science research can be translated into efficacious interventions for chronic disease populations. PMID:22963594

  6. Translating basic behavioral and social science research to clinical application: the EVOLVE mixed methods approach.

    PubMed

    Peterson, Janey C; Czajkowski, Susan; Charlson, Mary E; Link, Alissa R; Wells, Martin T; Isen, Alice M; Mancuso, Carol A; Allegrante, John P; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B

    2013-04-01

    To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease populations. We employed a sequential mixed methods model (EVOLVE) to design and test the PA/SA intervention in order to increase physical activity in people with coronary artery disease (post-percutaneous coronary intervention [PCI]) or asthma (ASM) and to improve medication adherence in African Americans with hypertension (HTN). In an initial qualitative phase, we explored participant values and beliefs. We next pilot tested and refined the intervention and then conducted 3 randomized controlled trials with parallel study design. Participants were randomized to combined PA/SA versus an informational control and were followed bimonthly for 12 months, assessing for health behaviors and interval medical events. Over 4.5 years, we enrolled 1,056 participants. Changes were sequentially made to the intervention during the qualitative and pilot phases. The 3 randomized controlled trials enrolled 242 participants who had undergone PCI, 258 with ASM, and 256 with HTN (n = 756). Overall, 45.1% of PA/SA participants versus 33.6% of informational control participants achieved successful behavior change (p = .001). In multivariate analysis, PA/SA intervention remained a significant predictor of achieving behavior change (p < .002, odds ratio = 1.66), 95% CI [1.22, 2.27], controlling for baseline negative affect, comorbidity, gender, race/ethnicity, medical events, smoking, and age. The EVOLVE method is a means by which basic behavioral science research can be translated into efficacious interventions for chronic disease populations.

  7. Teaching population health as a basic science at Harvard Medical School.

    PubMed

    Finkelstein, Jonathan A; McMahon, Graham T; Peters, Antoinette; Cadigan, Rebecca; Biddinger, Paul; Simon, Steven R

    2008-04-01

    In 2006-2007, Harvard Medical School implemented a new, required course for first-year medical and dental students entitled Clinical Epidemiology and Population Health. Conceived of as a "basic science" course, its primary goal is to allow students to develop an understanding of caring for individuals and promoting the health of populations as a continuum of strategies, all requiring the engagement of physicians. In the course's first iteration, topical content accessible to first-year students was selected to exemplify physicians' roles in addressing current threats to population health. Methodological areas included domains of clinical epidemiology, decision sciences, population-level prevention and health promotion, physicians' roles in the public health system, and population-level surveillance and intervention strategies. Large-group settings were selectively used to frame the relevance of each topic, and conceptual learning of statistical and epidemiologic methods occurred in conference groups of 24 students. Finally, tutorials of eight students and one or two faculty were used for critical reading of published studies, review of problem sets, and group discussion of population health issues. To help students appreciate the structure and function of the public health system and physicians' role in public health emergencies, the course included a role-playing exercise simulating response to an influenza pandemic. The first iteration of the course was well received, and assessment of students suggested mastery of basic skills. Preclinical courses represent a progressive step in developing a workforce of physicians who embrace their responsibility to improve the health of the population as a whole, as well as the health of the patient in front of them.

  8. Platelet-rich plasma in the pathologic processes of cartilage: review of basic science evidence.

    PubMed

    Smyth, Niall A; Murawski, Christopher D; Fortier, Lisa A; Cole, Brian J; Kennedy, John G

    2013-08-01

    The purpose of this study was to systematically review the basic science evidence for the use of platelet-rich plasma (PRP) in the treatment of pathologic processes of cartilage, both as an adjunct to cartilage repair and as a conservative management strategy for osteoarthritis, with the intent of determining the effect of PRP and whether a proof of concept for its use has been established to facilitate further investigation at a clinical level. Using the terms "platelet-rich plasma OR PRP OR autologous conditioned plasma OR ACP AND cartilage OR chondrocytes OR chondrogenesis OR osteoarthritis OR arthritis" we searched EMBASE and PubMed/Medline in April 2012. Two authors performed the search, 3 authors independently assessed the studies for inclusion, and 2 authors extracted the data. Extracted data included cytologic analysis of PRP, study design, and results. Twenty-one studies (12 in vitro, 8 in vivo, one in vitro and in vivo) met the inclusion criteria. The effects of PRP in these studies included increasing chondrocyte and mesenchymal stem cell proliferation, proteoglycan deposition, and type II collagen deposition. PRP was also found to increase the cell viability of chondrocytes and the migration and chondrogenic differentiation of mesenchymal stem cells (MSCs) and to inhibit the effect of catabolic cytokines. In vivo, PRP was used as an adjunct to concomitant surgical management, including microfracture surgery and implant, scaffold, and graft insertion. Not all studies concluded that PRP has a positive effect on cartilage repair. The current basic science evidence suggests that PRP has several potential effects on cartilage repair and osteoarthritis, and a proof of concept has been established. Well-designed randomized controlled trials (RCTs) are needed to extrapolate this evidence to the clinical setting. Copyright © 2013 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  9. Basic science and spine literature document bone morphogenetic protein increases cancer risk.

    PubMed

    Epstein, Nancy E

    2014-01-01

    Increasingly, clinical articles document that bone morphogenetic protein (BMP/INFUSE: Medtronic, Memphis, TN, USA) and its derivatives utilized in spinal surgery increase the risk of developing cancer. However, there is also a large body of basic science articles that also document that various types of BMP and other members of the TGF-Beta (transforming growth factor beta) family promote the growth of different types of cancers. This review looks at many clinical articles citing BMP/INFUSE's role, largely "off-label", in contributing to complications encountered during spinal surgery. Next, however, specific attention is given to the clinical and basic science literature regarding how BMP and its derivatives (e.g. members of the TGF-beta family) may also impact the development of breast and other cancers. Utilizing BMP/INFUSE in spine surgery increased the risk of cancers/new malignancy as documented in several studies. For example, Carragee et al. found that for single-level instrumented posterolateral fusions (PLF) using high-dose rhBMP-2 (239 patients) vs. autograft (control group; n = 224), the risks of new cancers at 2 and 5 years postoperatively were increased. In laboratory studies, BMP's along with other members of the TGF-Beta family also modulated/contributed to the proliferation/differentiation of breast cancer (e.g. bone formation/turnover, breast cancer-related solid tumors, and metastases), lung, adrenal, and colon cancer. BMP/INFUSE when utilized clinically in spinal fusion surgery appears to promote cancer at higher rates than observed in the overall population. Furthermore, BMP and TGF-beta are correlated with increased cancer growth both in the clinic and the laboratory.

  10. Knowledge loss of medical students on first year basic science courses at the University of Saskatchewan.

    PubMed

    D'Eon, Marcel F

    2006-01-14

    Many senior undergraduate students from the University of Saskatchewan indicated informally that they did not remember much from their first year courses and wondered why we were teaching content that did not seem relevant to later clinical work or studies. To determine the extent of the problem a course evaluation study that measured the knowledge loss of medical students on selected first year courses was conducted. This study replicates previous memory decrement studies with three first year medicine basic science courses, something that was not found in the literature. It was expected that some courses would show more and some courses would show less knowledge loss. In the spring of 2004 over 20 students were recruited to retake questions from three first year courses: Immunology, physiology, and neuroanatomy. Student scores on the selected questions at the time of the final examination in May 2003 (the 'test') were compared with their scores on the questions 10 or 11 months later (the 're-test') using paired samples t -tests. A repeated-measures MANOVA was used to compare the test and re-test scores among the three courses. The re-test scores were matched with the overall student ratings of the courses and the student scores on the May 2003 examinations. A statistically significant main effect of knowledge loss (F = 297.385; p < .001) and an interaction effect by course (F = 46.081; p < .001) were found. The students' scores in the Immunology course dropped 13.1%, 46.5% in Neuroanatomy, and 16.1% in physiology. Bonferroni post hoc comparisons showed a significant difference between Neuroanatomy and Physiology (mean difference of 10.7, p = .004). There was considerable knowledge loss among medical students in the three basic science courses tested and this loss was not uniform across courses. Knowledge loss does not seem to be related to the marks on the final examination or the assessment of course quality by the students.

  11. Use of a clinical seminar to horizontally integrate basic science and clinical topics for year-one students.

    PubMed

    Green, Bart N; Johnson, Claire D; Vuong, Jill; Luckock, Arlene S; Waagen, Gerald

    2008-01-01

    To describe a clinical seminar introduced to integrate basic science and clinical topics for first-quarter chiropractic students. A 2-hour interactive seminar was created to integrate information from a diverse array of basic science and clinical courses that students undertake during the first quarter of a chiropractic degree program. A patient from teaching clinic served as the clinical focus for integrating basic science and clinical topics. Student knowledge, confidence in knowledge and perceptions of the program were assessed using blinded questionnaires. Changes in student knowledge were analyzed using the sign test. Changes in student confidence in knowledge were assessed using the Wilcoxon Signed Rank test for two related samples. Student perceptions of the experience were assessed using six Likert items and written comments that were analyzed qualitatively. One hundred ten students participated in the seminar. A statistically significant improvement in student knowledge and confidence in knowledge was observed immediately following the seminar. Student satisfaction with the program was considered high, based on questionnaire scores. Overall, attendance at the seminar enhanced student clinical and basic science knowledge and confidence in knowledge gained. Students found the seminar enjoyable, and the seminar achieved the goal of integrating clinical information with basic science information.

  12. International Space Science Programs: Basic Research with a High Public Purpose

    NASA Astrophysics Data System (ADS)

    Baker, D. N.

    2009-04-01

    The exploration of outer space, and the use of platforms in space to monitor the Earth, are increasingly international enterprises. The spacefaring nations of the world have programs to study the moon, the Sun, the other planets of the solar system, and the universe beyond. Space is also the domain from which navigation, communication, reconnaissance, and resource management functions are carried out by civilian and military agencies. Recent decades of experience have shown the immense benefits of international cooperation to pursue scientific research goals. In turn, the products of such basic research have immense potential to improve space situational awareness and to mitigate the effects of ''space weather'' on human technology. A key to future success of space exploration is to minimize the impacts of laws and regulations such as ITAR (International Traffic in Arms Regulations) that have already had a devastating effect on space commerce and basic space research. In this presentation I discuss the conduct of forefront science in the context of sensible, prudent international space policy and evolving governmental regulations.

  13. Basic Sciences in Development: What Changes Will We See in Transplantation in the Next 5 Years?

    PubMed

    Baan, Carla C

    2016-12-01

    Over 3000 delegates attended the 26th International Congress of the Transplantation Society in Hong Kong, which marked the 50th anniversary of the society. In his presidential address, Professor Phil O'Connell from the Westmead Hospital in Sydney, Australia, commented that a major challenge for the future is improving long-term outcomes after solid organ transplantation. He highlighted that 40% of transplanted organs are lost within 10 years, and that a high proportion of patients suffer from immunosuppression-related side effects. These 2 issues are the key drivers for basic scientists in the field of transplantation. A deeper understanding of the biological mechanisms involved, and more accurate identification of patients at risk for poor outcomes or drug-related adverse effects, will ultimately help to address these problems and improve graft survival rates and patients' quality of life. The research was more diverse than ever before, reflecting the variety and complexity of the many processes which underlie outcomes after transplantation, and the need to broaden our thinking when seeking solutions to the wide-ranging complications which face the transplant team. This article explores the latest developments in basic science presented at the Congress which may offer new insights and solutions to the current challenges in organ transplantation. With so many interesting papers presented, it is impossible to discuss everything, but some key areas are considered.

  14. Pharmacology education in North American dental schools: the basic science survey series.

    PubMed

    Gautam, Medha; Shaw, David H; Pate, Ted D; Lambert, H Wayne

    2013-08-01

    As part of the Basic Science Survey Series (BSSS) for Dentistry, members of the American Dental Education Association (ADEA) Physiology, Pharmacology, and Therapeutics Section surveyed course directors of basic pharmacology courses in North American dental schools. The survey was designed to assess, among other things, faculty affiliation and experience of course directors, teaching methods, general course content and emphasis, extent of interdisciplinary (shared) instruction, and impact of recent curricular changes. Responses were received from forty-nine of sixty-seven (73.1 percent) U.S. and Canadian dental schools. The findings suggest the following: 1) substantial variation exists in instructional hours, faculty affiliation, placement within curriculum, class size, and interdisciplinary nature of pharmacology courses; 2) pharmacology course content emphasis is similar among schools; 3) the number of contact hours in pharmacology has remained stable over the past three decades; 4) recent curricular changes were often directed towards enhancing the integrative and clinically relevant aspects of pharmacology instruction; and 5) a trend toward innovative content delivery, such as use of computer-assisted instruction applications, is evident. Data, derived from this study, may be useful to pharmacology course directors, curriculum committees, and other dental educators with an interest in integrative and interprofessional education.

  15. Historical Roots of the Energy Crisis: A Basic Bibliography of Energy History.

    ERIC Educational Resources Information Center

    Ferguson, Eugene S.

    1982-01-01

    Intended for nonspecialists, discusses various aspects of energy in historical terms. Areas addressed include brevity of the cheap energy era, exponential growth, and ideology/controversey (suggesting relationships between power plants and economic power). Examines general literature providing a framework for qualitative thinking about energy and…

  16. Europa Science Platforms and Kinetic Energy Probes

    NASA Technical Reports Server (NTRS)

    Hays, C. C.; Klein, G. A.

    2003-01-01

    This presentation will outline a proposed mission for the Jupiter Icy Moons Orbiter (JIMO). The mission outlined will concentrate on an examination of Europa. Some of the primary science goals for the JIMO mission are: 1) to answer broad science questions, 2) improved knowledge of Jovian system; specifically, lunar geological and geophysical properties, 3) chemical composition of Jovian lunar surfaces and subterranean matter, and 4) the search for life. In order to address these issues, the experiment proposed here will deploy orbiting, surface, and subterranean science platforms.

  17. Europa Science Platforms and Kinetic Energy Probes

    NASA Technical Reports Server (NTRS)

    Hays, C. C.; Klein, G. A.

    2003-01-01

    This presentation will outline a proposed mission for the Jupiter Icy Moons Orbiter (JIMO). The mission outlined will concentrate on an examination of Europa. Some of the primary science goals for the JIMO mission are: 1) to answer broad science questions, 2) improved knowledge of Jovian system; specifically, lunar geological and geophysical properties, 3) chemical composition of Jovian lunar surfaces and subterranean matter, and 4) the search for life. In order to address these issues, the experiment proposed here will deploy orbiting, surface, and subterranean science platforms.

  18. Strengthening faculty recruitment for health professions training in basic sciences in Zambia.

    PubMed

    Simuyemba, Moses; Talib, Zohray; Michelo, Charles; Mutale, Wilbroad; Zulu, Joseph; Andrews, Ben; Nzala, Selestine; Katubulushi, Max; Njelesani, Evariste; Bowa, Kasonde; Maimbolwa, Margaret; Mudenda, John; Mulla, Yakub

    2014-08-01

    Zambia is facing a crisis in its human resources for health, with deficits in the number and skill mix of health workers. The University of Zambia School of Medicine (UNZA SOM) was the only medical school in the country for decades, but recently it was joined by three new medical schools--two private and one public. In addition to expanding medical education, the government has also approved several allied health programs, including pharmacy, physiotherapy, biomedical sciences, and environmental health. This expansion has been constrained by insufficient numbers of faculty. Through a grant from the Medical Education Partnership Initiative (MEPI), UNZA SOM has been investing in ways to address faculty recruitment, training, and retention. The MEPI-funded strategy involves directly sponsoring a cohort of faculty at UNZA SOM during the five-year grant, as well as establishing more than a dozen new master's programs, with the goal that all sponsored faculty are locally trained and retained. Because the issue of limited basic science faculty plagues medical schools throughout Sub-Saharan Africa, this strategy of using seed funding to build sustainable local capacity to recruit, train, and retain faculty could be a model for the region.

  19. Clinical and basic science research in sexual medicine must rely, in part, on pharmaceutical funding?

    PubMed

    Jannini, Emmanuele A; Eardley, Ian; Sand, Michael; Hackett, Geoffrey

    2010-07-01

    The conflict of interest in sexual medicine (SM) is a never-ending debate between scientists who consider possible and fruitful the partnership between science and the pharmaceutical industry (pharma) and others who are afraid that such a relationship might contaminate the veracity of scientific research. The aim of this Controversy is to appreciate opinions from both perspectives. Four scientists (three from academic or private practice and one employee of the industry) with expertise in the area of SM were asked to contribute with their opinions. Expert opinion supported by the critical review of the currently available literature. Expert #1, who is Controversy's section editor, and Expert #3 consider industry involvement in the field of SM problematic but potentially synergistic with the aim of science. On the other side, the Experts #2 and 4 argue that it is almost impossible to serve two masters. They believe that the pharma involved both in basic and applied research may jeopardize the independent evolution of the young SM. After reading this Controversy, The Journal of Sexual Medicine's readers should be able to judge by themselves the claims of the discussants and if the partnership between industry and SM is a risk or a potential benefit.

  20. Strengthening Faculty Recruitment for Health Professions Training in Basic Sciences in Zambia

    PubMed Central

    Simuyemba, Moses; Talib, Zohray; Michelo, Charles; Mutale, Wilbroad; Zulu, Joseph; Andrews, Ben; Katubulushi, Max; Njelesani, Evariste; Bowa, Kasonde; Maimbolwa, Margaret; Mudenda, John; Mulla, Yakub

    2014-01-01

    Zambia is facing a crisis in its human resources for health (HRH), with deficits in the number and skill mix of health workers. The University of Zambia School of Medicine (UNZA SOM) was the only medical school in the country for decades, but recently it was joined by three new medical schools—two private and one public. In addition to expanding medical education, the government has also approved several allied health programs, including pharmacy, physiotherapy, biomedical sciences, and environmental health. This expansion has been constrained by insufficient numbers of faculty. Through a grant from the Medical Education Partnership Initiative (MEPI), UNZA SOM has been investing in ways to address faculty recruitment, training, and retention. The MEPI-funded strategy involves directly sponsoring a cohort of faculty at UNZA SOM during the five-year grant, as well as establishing more than a dozen new master’s programs, with the goal that all sponsored faculty are locally trained and retained. Because the issue of limited basic science faculty plagues medical schools throughout Sub-Saharan Africa, this strategy of using seed funding to build sustainable local capacity to recruit, train, and retain faculty could be a model for the region. PMID:25072591