Sample records for basic pressure production

  1. 30 CFR 250.528 - What must I include in my casing pressure request?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... calculated MAWOPs; (h) All casing/riser pre-bleed down pressures; (i) Shut-in tubing pressure; (j) Flowing tubing pressure; (k) Date and the calculated daily production rate during last well test (oil, gas, basic...); (m) Well type (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well schematic; (p...

  2. 30 CFR 250.527 - What must I include in my casing pressure request?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... calculated MAWOPs; (h) All casing/riser pre-bleed down pressures; (i) Shut-in tubing pressure; (j) Flowing tubing pressure; (k) Date and the calculated daily production rate during last well test (oil, gas, basic...); (m) Well type (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well schematic; (p...

  3. 30 CFR 250.528 - What must I include in my casing pressure request?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... calculated MAWOPs; (h) All casing/riser pre-bleed down pressures; (i) Shut-in tubing pressure; (j) Flowing tubing pressure; (k) Date and the calculated daily production rate during last well test (oil, gas, basic...); (m) Well type (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well schematic; (p...

  4. The good laboratory practice and good clinical practice requirements for the production of radiopharmaceuticals in clinical research.

    PubMed

    De Vos, Filip J; De Decker, Mario; Dierckx, Rudi A

    2005-07-01

    Radiopharmaceuticals account for more than 95% of the group of sterile pharmaceutical products and should therefore be handled and produced with care. Since the introduction of the European directive, all pharmaceuticals used in clinical studies must be prepared under good manufacturing practice (GMP) conditions. This review aims to give an overview of the basic principles and guidelines for the preparation of radiopharmaceuticals. Special attention is given to the production area environment and personnel, the two basic requirements for GMP productions. Especially for the production area, two philosophies have to be combined: the cascade system of over-pressure for the production of pharmaceuticals and the under pressure system for the manufacturing of radioisotopes. Personnel should be selected based on education and regularly given special training for the handling of radioactive material. Compared to pharmaceuticals, radiopharmaceuticals have their own labels, taking into account their specific nature. Besides the standard quality control, other items for quality control of radiopharmaceuticals are also discussed in this article.

  5. Compression stockings for treating venous leg ulcers: measurement of interface pressure under a new ulcer kit.

    PubMed

    Partsch, B; Partsch, H

    2008-01-01

    The aim of this study was to measure the interface pressure of a newly designed two-layer compression stocking (Mediven ulcer kit Medi QMBH, Bayreuth, Germany) in different body positions and to compare the values with those obtained with another two-layer product. Interface pressure was measured on the distal medial leg in 16 legs of volunteers, with the basic layer alone and with the whole stocking kit in the supine, sitting and standing position for both stocking systems. The literature concerning ulcer-healing rates is reviewed. Mediven ulcerkit produced statistically significant higher pressure values than the ulcer stocking with a median resting value of 35.5 mmHg in the supine and 42.5 mmHg in the standing position. The pressure while standing comes close to values exerted by bandages. The basic layer alone applies a pressure of 20.5 mmHg. Especially designed compression stockings exerting sufficient interface pressure may be indicated in patients with small ulcers of short duration.

  6. Flight evaluation of an engine static pressure noseprobe in an F-15 airplane

    NASA Technical Reports Server (NTRS)

    Foote, C. H.; Jaekel, R. F.

    1981-01-01

    The flight testing of an inlet static pressure probe and instrumented inlet case produced results consistent with sea-level and altitude stand testing. The F-15 flight test verified the basic relationship of total to static pressure ratio versus corrected airflow and automatic distortion downmatch with the engine pressure ratio control mode. Additionally, the backup control inlet case statics demonstrated sufficient accuracy for backup control fuel flow scheduling, and the station 6 manifolded production probe was in agreement with the flight test station 6 tota pressure probes.

  7. 30 CFR 250.527 - What must I include in my casing pressure request?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and the calculated daily production rate during last well test (oil, gas, basic sediment, and water... (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well schematic; (p) Water depth; (q...: (1) Bleed down/buildup test; (2) Shut-in the well and monitor the pressure drop test; (3) Constant...

  8. The spectral properties of uranium hexafluoride and its thermal decomposition products

    NASA Technical Reports Server (NTRS)

    Krascella, N. L.

    1976-01-01

    This investigation was initiated to provide basic spectral data for gases of interest to the plasma core reactor concept. The attenuation of vacuum ultraviolet (VUV) radiation by helium at pressures up to 20 atm over path lengths of about 61 cm and in the approximate wavelength range between 80 and 300 nm was studied. Measurements were also conducted to provide basic VUV data with respect to UF6 and UF6/argon mixtures in the wavelength range between 80 and 120 nm. Finally, an investigation was initiated to provide basic spectral emission and absorption data for UF6 and possible thermal decomposition products of UF6 at elevated temperatures.

  9. Western Shallow Oil Zone, Elk Hills Field, Kern County, California: General reservoir study, Appendix 4, Fourth Wilhelm sand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carey, K.B.

    1987-09-01

    The general Reservoir Study of the Western Shallow Oil Zone was prepared by Evans, Carey and Crozier as Task Assignment 009 with the United States Department of Energy. This study, Appendix IV, addresses the Fourth Wilhelm Sand and its sub units and pools. Basic pressure, production and assorted technical data were provided by the US Department of Energy staff at Elk Hills. Basic pressure production and assorted technical data were provided by the US Department of Energy staff at Elk Hills. These data were accepted as furnished with no attempt being made by Evans, Carey and Crozier for independent verification.more » This study has identified the petrophysical properties and the past productive performance of the reservoir. Primary reserves have been determined and general means of enhancing future recovery have been suggested. It is hoped that this volume can now additionally serve as a take off point for exploitation engineers to develop specific programs toward the end. 12 figs., 9 tabs.« less

  10. Dynamic Pressure Microphones

    NASA Astrophysics Data System (ADS)

    Werner, E.

    In 1876, Alexander Graham Bell described his first telephone with a microphone using magnetic induction to convert the voice input into an electric output signal. The basic principle led to a variety of designs optimized for different needs, from hearing impaired users to singers or broadcast announcers. From the various sound pressure versions, only the moving coil design is still in mass production for speech and music application.

  11. Modeling of edge effect in subaperture tool influence functions of computer controlled optical surfacing.

    PubMed

    Wan, Songlin; Zhang, Xiangchao; He, Xiaoying; Xu, Min

    2016-12-20

    Computer controlled optical surfacing requires an accurate tool influence function (TIF) for reliable path planning and deterministic fabrication. Near the edge of the workpieces, the TIF has a nonlinear removal behavior, which will cause a severe edge-roll phenomenon. In the present paper, a new edge pressure model is developed based on the finite element analysis results. The model is represented as the product of a basic pressure function and a correcting function. The basic pressure distribution is calculated according to the surface shape of the polishing pad, and the correcting function is used to compensate the errors caused by the edge effect. Practical experimental results demonstrate that the new model can accurately predict the edge TIFs with different overhang ratios. The relative error of the new edge model can be reduced to 15%.

  12. Pressure-induced polymerization of acetylene: Structure-directed stereoselectivity and a possible route to graphane

    DOE PAGES

    Sun, Jiangman; Dong, Xiao; Wang, Yajie; ...

    2017-05-02

    Geometric isomerism in polyacetylene is a basic concept in chemistry textbooks. Polymerization to cis-isomer is kinetically preferred at low temperature, not only in the classic catalytic reaction in solution but also, unexpectedly, in the crystalline phase when it is driven by external pressure without a catalyst. Until now, no perfect reaction route has been proposed for this pressure-induced polymerization. Using in situ neutron diffraction and meta-dynamic simulation, we discovered that under high pressure, acetylene molecules react along a specific crystallographic direction that is perpendicular to those previously proposed. Moreover, following this route produces a pure cis-isomer and more surprisingly, predictsmore » that graphane is the final product. Experimentally, polycyclic polymers with a layered structure were identified in the recovered product by solid-state nuclear magnetic resonance and neutron pair distribution functions, which indicates the possibility of synthesizing graphane under high pressure.« less

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Jiangman; Dong, Xiao; Wang, Yajie

    Geometric isomerism in polyacetylene is a basic concept in chemistry textbooks. Polymerization to cis-isomer is kinetically preferred at low temperature, not only in the classic catalytic reaction in solution but also, unexpectedly, in the crystalline phase when it is driven by external pressure without a catalyst. Until now, no perfect reaction route has been proposed for this pressure-induced polymerization. Using in situ neutron diffraction and meta-dynamic simulation, we discovered that under high pressure, acetylene molecules react along a specific crystallographic direction that is perpendicular to those previously proposed. Moreover, following this route produces a pure cis-isomer and more surprisingly, predictsmore » that graphane is the final product. Experimentally, polycyclic polymers with a layered structure were identified in the recovered product by solid-state nuclear magnetic resonance and neutron pair distribution functions, which indicates the possibility of synthesizing graphane under high pressure.« less

  14. Manufacturing methods of a composite cell case for a Ni-Cd battery

    NASA Technical Reports Server (NTRS)

    Bauer, J. L.

    1979-01-01

    Basic manufacturing method refinements for using graphite epoxy material for a nickel cadmium battery cell case were performed to demonstrate production feasibility. The various facets of production scale-up, i.e., process and tooling development, together with material and process control, were integrated into a comprehensive manufacturing process that assures production reproducibility and product uniformity. Test results substantiate that a battery cell case produced from graphite epoxy pre-impregnated material, utilizing the internal pressure bag fabrication method, is feasible.

  15. Antihypertensive effects of continuous oral administration of nattokinase and its fragments in spontaneously hypertensive rats.

    PubMed

    Fujita, Mitsugu; Ohnishi, Katsunori; Takaoka, Shinsaku; Ogasawara, Kazuya; Fukuyama, Ryo; Nakamuta, Hiromichi

    2011-01-01

    To determine whether the antihypertensive effect of nattokinase is associated with the protease activity of this enzyme, we compared nattokinase with the fragments derived from nattokinase, which possessed no protease activity, in terms of the effect on hypertension in spontaneously hypertensive rats (SHR). In the continuous oral administration test, the groups were given a basic diet alone (control), the basic diet containing nattokinase (0.2, 2.6 mg/g diet) or the basic diet containing the fragments derived from nattokinase (0.2, 0.6 mg/g diet). The group fed the basic diet containing high-dosage nattokinase (2.6 mg/g diet) showed significant reductions in systolic blood pressure (SBP), diastolic blood pressure (DBP) and plasma fibrinogen level, compared with control group and no influence on activities of renin and angiotensin-converting enzyme (ACE, EC 3.4.15.1), and plasma angiotensin II level in the renin-angiotensin system. The treatment of the basic diet containing high-dosage fragments (0.6 mg/g diet) significantly decreased SBP, DBP and plasma angiotensin II level in plasma but the treatment did not influence on plasma fibrinogen level. These results suggest that nattokinase and its fragments are different from each other in the mechanism to reduce hypertension. Nattokinase, retained its protease activity after absorbance across the intestines, may decrease blood pressure through cleavage of fibrinogen in plasma. The fragments, which absorbed as nattokinase-degradation products, prevents the elevation of plasma angiotensin II level to suppress hypertension.

  16. Production of hydrocarbon fuels from pyrolysis of soybean oils using a basic catalyst.

    PubMed

    Xu, Junming; Jiang, Jianchun; Sun, Yunjuan; Chen, Jie

    2010-12-01

    Triglycerides obtained from animals and plants have attracted great attention from researchers for developing an environmental friendly and high-quality fuel, free of nitrogen and sulfur. In the present work, the production of biofuel by catalytic cracking of soybean oil over a basic catalyst in a continuous pyrolysis reactor at atmospheric pressure has been studied. Experiments were designed to study the effect of different types of catalysts on the yield and acid value of the diesel and gasoline fractions from the pyrolytic oil. It was found that basic catalyst gave a product with relatively low acid number. These pyrolytic oils were also further reacted with alcohol in order to decrease their acid value. After esterification, the physico-chemical properties of these biofuels were characterized, and compared with Chinese specifications for conventional diesel fuels. The results showed that esterification of pyrolytic oil from triglycerides represents an alternative technique for producing biofuels from soybean oils with characteristics similar to those of petroleum fuels. Published by Elsevier Ltd.

  17. Pressure-Induced Polymerization of Acetylene: Structure-Directed Stereoselectivity and a Possible Route to Graphane.

    PubMed

    Sun, Jiangman; Dong, Xiao; Wang, Yajie; Li, Kuo; Zheng, Haiyan; Wang, Lijuan; Cody, George D; Tulk, Christopher A; Molaison, Jamie J; Lin, Xiaohuan; Meng, Yufei; Jin, Changqing; Mao, Ho-Kwang

    2017-06-01

    Geometric isomerism in polyacetylene is a basic concept in chemistry textbooks. Polymerization to cis-isomer is kinetically preferred at low temperature, not only in the classic catalytic reaction in solution but also, unexpectedly, in the crystalline phase when it is driven by external pressure without a catalyst. Until now, no perfect reaction route has been proposed for this pressure-induced polymerization. Using in situ neutron diffraction and meta-dynamic simulation, we discovered that under high pressure, acetylene molecules react along a specific crystallographic direction that is perpendicular to those previously proposed. Following this route produces a pure cis-isomer and more surprisingly, predicts that graphane is the final product. Experimentally, polycyclic polymers with a layered structure were identified in the recovered product by solid-state nuclear magnetic resonance and neutron pair distribution functions, which indicates the possibility of synthesizing graphane under high pressure. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Nuclear Power from Fission Reactors. An Introduction.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Technical Information Center.

    The purpose of this booklet is to provide a basic understanding of nuclear fission energy and different fission reaction concepts. Topics discussed are: energy use and production, current uses of fuels, oil and gas consumption, alternative energy sources, fossil fuel plants, nuclear plants, boiling water and pressurized water reactors, the light…

  19. Manufacturing methods of a composite cell case for a Ni-Cd battery

    NASA Technical Reports Server (NTRS)

    Bauer, J. L.; Bogner, R. S.; Lowe, E. P.; Orlowski, E.

    1979-01-01

    Graphite epoxy material for a nickel cadmium battery cell case has been evaluated and determined to perform in the simulated environment of the battery. The basic manufacturing method requires refinement to demonstrate production feasibility. The various facets of production scale-up, i.e., process and tooling development together with material and process control, have been integrated into a comprehensive manufacturing process that assures production reproducibility and product uniformity. Test results substantiate that a battery cell case produced from graphite epoxy pre-impregnated material utilizing internal pressure bag fabrication method is feasible.

  20. Process for liquefying carbonaceous materials of high molecular weight and for separating liquefaction products

    DOEpatents

    Malek, John M.

    1977-01-01

    Process characterized by comprising successively a dissolution zone fed with carbonaceous solids and with a solvent, a high pressure hydrogenation zone provided with a source of hydrogen, and a hydrogenation products separation zone, wherein the improvement consists mainly in chemical upgrading of the liquidform products derived from the separation zone, and recycling a part of the upgraded products to the dissolution zone, this recycled part being of either positively acidic or positively basic properties for enhancing the dissolution - decomposition of base-acid structures present in the carbonaceous solid feed.

  1. Weeds and their effect on the performance of maize and fingermillet in the mid-hills of Nepal

    USDA-ARS?s Scientific Manuscript database

    Relay cropping of maize with fingermillet (maize/fingermillet) is the predominant cropping system for sustaining food security in the hilly regions of Nepal. In this region weed pressure severely reduces crop yields, yet basic information on weed species composition, biomass production and their eff...

  2. Carbon-free hydrogen production from low rank coal

    NASA Astrophysics Data System (ADS)

    Aziz, Muhammad; Oda, Takuya; Kashiwagi, Takao

    2018-02-01

    Novel carbon-free integrated system of hydrogen production and storage from low rank coal is proposed and evaluated. To measure the optimum energy efficiency, two different systems employing different chemical looping technologies are modeled. The first integrated system consists of coal drying, gasification, syngas chemical looping, and hydrogenation. On the other hand, the second system combines coal drying, coal direct chemical looping, and hydrogenation. In addition, in order to cover the consumed electricity and recover the energy, combined cycle is adopted as addition module for power generation. The objective of the study is to find the best system having the highest performance in terms of total energy efficiency, including hydrogen production efficiency and power generation efficiency. To achieve a thorough energy/heat circulation throughout each module and the whole integrated system, enhanced process integration technology is employed. It basically incorporates two core basic technologies: exergy recovery and process integration. Several operating parameters including target moisture content in drying module, operating pressure in chemical looping module, are observed in terms of their influence to energy efficiency. From process modeling and calculation, two integrated systems can realize high total energy efficiency, higher than 60%. However, the system employing coal direct chemical looping represents higher energy efficiency, including hydrogen production and power generation, which is about 83%. In addition, optimum target moisture content in drying and operating pressure in chemical looping also have been defined.

  3. Chemistry experience in the primary heat transport circuits of Kraftwerk Union pressurized water reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riess, R.

    Chosen for this description of the selected Kraftwerk Union (KWU) pressurized water reactor units were Obrigheim (KWO, 345 MW(e)), Stade (KKS, 662 (MW(e)), Borselle (KCB, 477 MW(e)), and Biblis (KWB-A, 1204 MW(e)). The experience at these plants shows that with a special startup procedure and a proper chemical control of the primary heat transport system that influences general corrosion, selective types of corrosion, corrosion product activity transport and resulting contamination, and radiation-induced decomposition, KWU units have no basic problems.

  4. Clinical and biomechanical perspectives on pressure injury prevention research: The case of prophylactic dressings.

    PubMed

    Gefen, A; Kottner, J; Santamaria, N

    2016-10-01

    In this perspective paper, we discuss clinical and biomechanical viewpoints on pressure injury (or pressure ulcer) prevention research. We have selected to focus on the case of prophylactic dressings for pressure injury prevention, and the background of the historical context of pressure injury research, as an exemplar to illuminate some of the good and not so good in current biomechanical and clinical research in the wound prevention and care arena. Investigators who are conducting medical or clinical research in academia, in medical settings or in industry to determine the efficacy of wound prevention and care products could benefit from applying some basic principles that are detailed in this paper, and that should leverage the research outcomes, thereby contributing to setting higher standards in the field. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Stress-strain analysis of contractility in the ileum in response to flow and ramp distension in streptozotocin-induced diabetic rats--association with advanced glycation end product formation.

    PubMed

    Zhao, Jingbo; Chen, Pengmin; Gregersen, Hans

    2015-04-13

    This study compared the ileal contractility and analyzed the association between contractility with advanced glycation end product (AGE) formation in normal and streptozotocin (STZ)-induced diabetic rats. Nine STZ-induced diabetic rats (Diabetes group) and 9 normal rats (Normal group) were used. The motility experiments were carried out on ileums in organ baths containing physiological Krebs solution. Ileal pressure and diameter changes were obtained from basic, flow-induced and ramp distension-induced contractions. The frequency and amplitude of contractions were analyzed from pressure-diameter curves. Distension-induced contraction thresholds and maximum contraction amplitude of basic and flow-induced contractions were calculated in terms of stress and strain. AGE and its receptor (RAGE) in the layers were detected by immunohistochemistry staining. The maximum stress of flow-induced contractions was lowest in the Diabetes Group (P<0.05). During ramp distension, the pressure and stress thresholds and Young's modulus to induce phasic contraction were lowest in the Diabetes Group (P<0.05 and P<0.01). AGE and RAGE expressions in the different ileum layers were highest in the Diabetes group. The contraction pressure and stress thresholds were significantly associated with AGE expression in the muscle layer and RAGE expression in mucosa epithelium and neurons. The diabetic intestine was hypersensitive to distension for contraction induction. However, the contraction force produced by smooth muscle was lowest in diabetic rats. Increased AGE/RAGE expression was associated with the contractility changes in diabetic rats. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Microbial production of biopolymers from the renewable resource wheat straw.

    PubMed

    Gasser, E; Ballmann, P; Dröge, S; Bohn, J; König, H

    2014-10-01

    Production of poly-ß-hydroxybutyrate (PHB) and the chemical basic compound lactate from the agricultural crop 'wheat straw' as a renewable carbon resource. A thermal pressure hydrolysis procedure for the breakdown of wheat straw was applied. By this means, the wheat straw was converted into a partially solubilized hemicellulosic fraction, consisting of sugar monomers, and an insoluble cellulosic fraction, containing cellulose, lignin and a small portion of hemicellulose. The insoluble cellulosic fraction was further hydrolysed by commercial enzymes in monomers. The production of PHB from the sugar monomers originating from hemicellulose or cellulose was achieved by the isolates Bacillus licheniformis IMW KHC 3 and Bacillus megaterium IMW KNaC 2. The basic chemical compound, lactate, a starting compound for the production of polylactide (PLA), was formed by some heterofermentative lactic acid bacteria (LAB) able to grow with xylose from the hemicellulosic wheat straw hydrolysate. Two strains were selected which were able to produce PHB from the sugars both from the hemicellulosic and the cellulosic fraction of the wheat straw. In addition, some of the LAB tested were capable of producing lactate from the hemicellulosic hydrolysate. The renewable resource wheat straw could serve as a substrate for microbiologically produced basic chemicals and biodegradable plastics. © 2014 The Society for Applied Microbiology.

  7. Synthesis of ammonia directly from air and water at ambient temperature and pressure

    NASA Astrophysics Data System (ADS)

    Lan, Rong; Irvine, John T. S.; Tao, Shanwen

    2013-01-01

    The N≡N bond (225 kcal mol-1) in dinitrogen is one of the strongest bonds in chemistry therefore artificial synthesis of ammonia under mild conditions is a significant challenge. Based on current knowledge, only bacteria and some plants can synthesise ammonia from air and water at ambient temperature and pressure. Here, for the first time, we report artificial ammonia synthesis bypassing N2 separation and H2 production stages. A maximum ammonia production rate of 1.14 × 10-5 mol m-2 s-1 has been achieved when a voltage of 1.6 V was applied. Potentially this can provide an alternative route for the mass production of the basic chemical ammonia under mild conditions. Considering climate change and the depletion of fossil fuels used for synthesis of ammonia by conventional methods, this is a renewable and sustainable chemical synthesis process for future.

  8. Synthesis of ammonia directly from air and water at ambient temperature and pressure

    PubMed Central

    Lan, Rong; Irvine, John T. S.; Tao, Shanwen

    2013-01-01

    The N≡N bond (225 kcal mol−1) in dinitrogen is one of the strongest bonds in chemistry therefore artificial synthesis of ammonia under mild conditions is a significant challenge. Based on current knowledge, only bacteria and some plants can synthesise ammonia from air and water at ambient temperature and pressure. Here, for the first time, we report artificial ammonia synthesis bypassing N2 separation and H2 production stages. A maximum ammonia production rate of 1.14 × 10−5 mol m−2 s−1 has been achieved when a voltage of 1.6 V was applied. Potentially this can provide an alternative route for the mass production of the basic chemical ammonia under mild conditions. Considering climate change and the depletion of fossil fuels used for synthesis of ammonia by conventional methods, this is a renewable and sustainable chemical synthesis process for future. PMID:23362454

  9. Synthesis of ammonia directly from air and water at ambient temperature and pressure.

    PubMed

    Lan, Rong; Irvine, John T S; Tao, Shanwen

    2013-01-01

    The N≡N bond (225 kcal mol⁻¹) in dinitrogen is one of the strongest bonds in chemistry therefore artificial synthesis of ammonia under mild conditions is a significant challenge. Based on current knowledge, only bacteria and some plants can synthesise ammonia from air and water at ambient temperature and pressure. Here, for the first time, we report artificial ammonia synthesis bypassing N₂ separation and H₂ production stages. A maximum ammonia production rate of 1.14 × 10⁻⁵ mol m⁻² s⁻¹ has been achieved when a voltage of 1.6 V was applied. Potentially this can provide an alternative route for the mass production of the basic chemical ammonia under mild conditions. Considering climate change and the depletion of fossil fuels used for synthesis of ammonia by conventional methods, this is a renewable and sustainable chemical synthesis process for future.

  10. Short-bearing approximation for full journal bearings

    NASA Technical Reports Server (NTRS)

    Ocvirk, F W

    1952-01-01

    A short-bearing approximation of pressure distribution in the oil film is presented which is an extension of the pressure-distribution function of Michell and Cardullo and includes end-leakage effects. Equations giving applied load, attitude angle, location and magnitude of peak film pressure, friction, and required oil flow rate as functions of the eccentricity ratio are also given. The capacity number, a basic non dimensional quantity resulting from this analysis is the product of the Sommerfeld number and the square of the length-diameter ratio. Curves determined by this analysis are compared with previously published experimental data and theoretical curves of Sommerfeld and Cameron and Wood. Conclusions reached indicate that this approximation is of practical value for analysis of short bearings.

  11. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion.

    PubMed

    Yan, Jing; Nadell, Carey D; Stone, Howard A; Wingreen, Ned S; Bassler, Bonnie L

    2017-08-23

    Biofilms, surface-attached communities of bacteria encased in an extracellular matrix, are a major mode of bacterial life. How the material properties of the matrix contribute to biofilm growth and robustness is largely unexplored, in particular in response to environmental perturbations such as changes in osmotic pressure. Here, using Vibrio cholerae as our model organism, we show that during active cell growth, matrix production enables biofilm-dwelling bacterial cells to establish an osmotic pressure difference between the biofilm and the external environment. This pressure difference promotes biofilm expansion on nutritious surfaces by physically swelling the colony, which enhances nutrient uptake, and enables matrix-producing cells to outcompete non-matrix-producing cheaters via physical exclusion. Osmotic pressure together with crosslinking of the matrix also controls the growth of submerged biofilms and their susceptibility to invasion by planktonic cells. As the basic physicochemical principles of matrix crosslinking and osmotic swelling are universal, our findings may have implications for other biofilm-forming bacterial species.Most bacteria live in biofilms, surface-attached communities encased in an extracellular matrix. Here, Yan et al. show that matrix production in Vibrio cholerae increases the osmotic pressure within the biofilm, promoting biofilm expansion and physical exclusion of non-matrix producing cheaters.

  12. Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring.

    PubMed

    Elias, Merrill F; Sullivan, Lisa M; Elias, Penelope K; D'Agostino, Ralph B; Wolf, Philip A; Seshadri, Sudha; Au, Rhoda; Benjamin, Emelia J; Vasan, Ramachandran S

    2007-03-01

    The purpose of this study was to determine whether echocardiographic left ventricular mass is related to cognitive performance beyond casual blood pressure adjusting for the influence of other vascular risk factors. We used multivariable regression analyses to relate left ventricular mass assessed at a routine examination (1995-1998) to measures of cognitive ability obtained routinely (1998-2001) in 1673 Framingham Offspring Study participants (56% women; mean age: 57 years) free from stroke, transient ischemic attack, and dementia. We adjusted for the following covariates hierarchically: (1) age, education, sex, body weight, height, interval between left ventricular mass measurement and neuropsychological testing (basic model); (2) basic model+blood pressure+treatment for hypertension; and (3) basic model+blood pressure+treatment for hypertension+vascular risk factors and prevalent cardiovascular disease. For the basic model, left ventricular mass was inversely associated with abstract reasoning (similarities), visual-spatial memory and organization, and verbal memory. For the basic model+blood pressure+treatment for hypertension, left ventricular mass was inversely associated with similarities and visual-spatial memory and organization. For the basic+blood pressure+treatment for hypertension+risk factors+cardiovascular disease model, no significant associations were observed. Echocardiographic left ventricular mass is associated with cognitive performance beyond casual and time-averaged systolic blood pressure, but this association is attenuated and rendered nonsignificant with additional adjustment for cardiovascular risk factors and cardiovascular disease, thus suggesting that these variables play an important role in mediating the association between left ventricular mass and cognition.

  13. Acidic leaching both of zinc and iron from basic oxygen furnace sludge.

    PubMed

    Trung, Zuzana Hoang; Kukurugya, Frantisek; Takacova, Zita; Orac, Dusan; Laubertova, Martina; Miskufova, Andrea; Havlik, Tomas

    2011-09-15

    During the steel production in the basic oxygen furnace (BOF), approximately 7-15 kg of dust per tonne of produced steel is generated. This dust contains approximately 1.4-3.2% Zn and 54-70% Fe. Regarding the zinc content, the BOF dust is considered to be highly problematic, and therefore new technological processes for recycling dusts and sludge from metallurgical production are still searched for. In this study the hydrometallurgical processing of BOF sludge in the sulphuric acid solutions under atmospheric pressure and temperatures up to 100 °C is investigated on laboratory scale. The influence of sulphuric acid concentration, temperature, time and liquid to solid ratio (L:S) on the leaching process was studied. The main aim of this study was to determine optimal conditions when the maximum amount of zinc passes into the solution whilst iron remains in a solid residue. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. Unit mechanisms of fission gas release: Current understanding and future needs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tonks, Michael; Andersson, David; Devanathan, Ram

    Gaseous fission product transport and release has a large impact on fuel performance, degrading fuel properties and, once the gas is released into the gap between the fuel and cladding, lowering gap thermal conductivity and increasing gap pressure. While gaseous fission product behavior has been investigated with bulk reactor experiments and simplified analytical models, recent improvements in experimental and modeling approaches at the atomistic and mesoscales are being applied to provide unprecedented understanding of the unit mechanisms that define the fission product behavior. In this article, existing research on the basic mechanisms behind the various stages of fission gas releasemore » during normal reactor operation are summarized and critical areas where experimental and simulation work is needed are identified. This basic understanding of the fission gas behavior mechanisms has the potential to revolutionize our ability to predict fission product behavior during reactor operation and to design fuels that have improved fission product retention. In addition, this work can serve as a model on how a coupled experimental and modeling approach can be applied to understand the unit mechanisms behind other critical behaviors in reactor materials.« less

  15. 24 CFR 200.926e - Supplemental information for use with the CABO One and Two Family Dwelling Code.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... shall be in accordance with section 7 of ASCE 7-88. (c) Wind pressures. The minimum Design Wind Pressures (net pressures) set forth below apply to areas designated as experiencing basic wind speeds up to and including 80 mph, as shown in ASCE 7-88, Figure 1, Basic Wind Speed Map. These pressures also...

  16. 24 CFR 200.926e - Supplemental information for use with the CABO One and Two Family Dwelling Code.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... shall be in accordance with section 7 of ASCE 7-88. (c) Wind pressures. The minimum Design Wind Pressures (net pressures) set forth below apply to areas designated as experiencing basic wind speeds up to and including 80 mph, as shown in ASCE 7-88, Figure 1, Basic Wind Speed Map. These pressures also...

  17. 24 CFR 200.926e - Supplemental information for use with the CABO One and Two Family Dwelling Code.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... shall be in accordance with section 7 of ASCE 7-88. (c) Wind pressures. The minimum Design Wind Pressures (net pressures) set forth below apply to areas designated as experiencing basic wind speeds up to and including 80 mph, as shown in ASCE 7-88, Figure 1, Basic Wind Speed Map. These pressures also...

  18. 24 CFR 200.926e - Supplemental information for use with the CABO One and Two Family Dwelling Code.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shall be in accordance with section 7 of ASCE 7-88. (c) Wind pressures. The minimum Design Wind Pressures (net pressures) set forth below apply to areas designated as experiencing basic wind speeds up to and including 80 mph, as shown in ASCE 7-88, Figure 1, Basic Wind Speed Map. These pressures also...

  19. 24 CFR 200.926e - Supplemental information for use with the CABO One and Two Family Dwelling Code.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... shall be in accordance with section 7 of ASCE 7-88. (c) Wind pressures. The minimum Design Wind Pressures (net pressures) set forth below apply to areas designated as experiencing basic wind speeds up to and including 80 mph, as shown in ASCE 7-88, Figure 1, Basic Wind Speed Map. These pressures also...

  20. The Balanced Development of Basic Education in the Context of Globalization

    ERIC Educational Resources Information Center

    Sun, Qi-lin; Kong, Kai

    2006-01-01

    Basic education is not only an essential means for eliminating stratification and differences in society but also one of the main reasons for the enlargement of the gap between the rich and the poor. Because it faces pressure in the context of globalization, a balanced development of basic education would be a good way to relieve this pressure.…

  1. Injection Molding Parameters Calculations by Using Visual Basic (VB) Programming

    NASA Astrophysics Data System (ADS)

    Tony, B. Jain A. R.; Karthikeyen, S.; Alex, B. Jeslin A. R.; Hasan, Z. Jahid Ali

    2018-03-01

    Now a day’s manufacturing industry plays a vital role in production sectors. To fabricate a component lot of design calculation has to be done. There is a chance of human errors occurs during design calculations. The aim of this project is to create a special module using visual basic (VB) programming to calculate injection molding parameters to avoid human errors. To create an injection mold for a spur gear component the following parameters have to be calculated such as Cooling Capacity, Cooling Channel Diameter, and Cooling Channel Length, Runner Length and Runner Diameter, Gate Diameter and Gate Pressure. To calculate the above injection molding parameters a separate module has been created using Visual Basic (VB) Programming to reduce the human errors. The outcome of the module dimensions is the injection molding components such as mold cavity and core design, ejector plate design.

  2. Different types of interactions of links in artificial and natural ecosystems under anthropogenic pressure

    NASA Astrophysics Data System (ADS)

    Somova, Lydia; Pisman, Tamara; Mikheeva, Galina; Pechurkin, Nickolay

    The life of organisms in an ecosystem depends not only on abiotic factors, but also on the interaction of organisms in which they come with each other. The study of mechanisms of the bioregulation based on ecological - biochemical interactions of ecosystem links is necessary to know the ecosystem development, its stability, survival of ecosystem organisms. It is of high importance as for the creation of artificial ecosystems, and also for the study of natural ecosystems under anthropogenic pressure on them. To create well-functioning ecosystems is necessary to study and consider the basic types of relationships between organisms. The basic types of interactions between organisms have been studied with simple terrestrial and water ecosystems. 1. The interaction of microbiocenoses and plants were studied in experiments with agrocenoses. Microbiocenosis proposed for increase of productivity of plants and for obtaining ecologically pure production of plants has been created taking into account mutual relationships between species of microorganisms. 2. The experimental model of the atmosphere closed «autotroph - heterotroph» system in which heterotrophic link was the mixed population of yeasts (Candida utilis and Candida guilliermondii) was studied. The algae Chlorella vulgaris was used as an autotroph link. It was shown, that the competition result for heterotrophic link depended on strategy of populations of yeast in relation to a substrate and oxygen utilization. 3. As a result of experimental and theoretical modelling of a competition of algae Chlorella vulgaris and Scenedesmus quadricauda at continuous cultivation, the impossibility of their coexistence in the conditions of limitation on nitrogen was shown. 4. Pray-predator interactions between algae (Chlorella vulgaris, Scenedesmus quadricauda) and invertebrates (Paramecium caudatum, Brachionus plicatilis) were studied in experimental closed ecosystem. This work was partly supported by the Russian Foundation for Basic Research, project No.13-06-00060

  3. Genetic link between EMI and EMII: An adakite connection

    NASA Astrophysics Data System (ADS)

    Shimoda, Gen

    2009-10-01

    Geochemical modeling of the origin of enriched mantle I (EMI) and enriched mantle II (EMII) is conducted from the perspective of adakite production. For the model, the average composition of adakites is re-estimated from published data for eighteen trace elements. Although the concentrations determined for highly incompatible elements are very high (about 100 times of primitive mantle), these high concentrations can be explained by melting of oceanic crust without sediment contribution. The compiled data further suggest that the mantle-slab melt reaction would play a major role in the production of basic adakites. In addition, crystal fractionation in the magma chamber should produce additional chemical variations in adakites, in particular for acidic adakites. To examine the effect of chemical variations on the isotopic composition of recycled adakites, broad correlations between trace elements and SiO 2 concentrations, and the MELTS program are employed. The results suggest that recycling of a basic adakite (SiO 2 = 55%) can account for EMI isotopic signatures with storage times of about 2.0 Gyr. The isotopic compositions of less-basic adakites and their evolved magmas shift towards EMII values with increasing SiO 2 concentrations. In particular, evolved acidic adakite can yield EMII isotopic signatures. These lines of evidence suggest that the recycling of adakites at various stages of evolution can conceivably produce the entire isotopic range between EMI and EMII reservoirs. Consequently, adakite recycling via sediment subduction or subduction erosion can account for the origins of EMI and EMII reservoirs. In this context, residual garnet under high pressure and plagioclase fractionation at low pressure might play an essential role in producing the chemical variations among adakites that ultimately govern the isotopic compositions of these geochemical reservoirs.

  4. Computer program for calculation of oxygen uptake

    NASA Technical Reports Server (NTRS)

    Castle, B. L.; Castle, G.; Greenleaf, J. E.

    1979-01-01

    A description and operational precedures are presented for a computer program, written in Super Basic, that calculates oxygen uptake, carbon dioxide production, and related ventilation parameters. Program features include: (1) the option of entering slope and intercept values of calibration curves for the O2 and CO2 and analyzers; (2) calculation of expired water vapor pressure; and (3) the option of entering inspured O2 and CO2 concentrations. The program is easily adaptable for programmable laboratory calculators.

  5. Numerical study of canister filters with alternatives filter cap configurations

    NASA Astrophysics Data System (ADS)

    Mohammed, A. N.; Daud, A. R.; Abdullah, K.; Seri, S. M.; Razali, M. A.; Hushim, M. F.; Khalid, A.

    2017-09-01

    Air filtration system and filter play an important role in getting a good quality air into turbo machinery such as gas turbine. The filtration system and filter has improved the quality of air and protect the gas turbine part from contaminants which could bring damage. During separation of contaminants from the air, pressure drop cannot be avoided but it can be minimized thus helps to reduce the intake losses of the engine [1]. This study is focused on the configuration of the filter in order to obtain the minimal pressure drop along the filter. The configuration used is the basic filter geometry provided by Salutary Avenue Manufacturing Sdn Bhd. and two modified canister filter cap which is designed based on the basic filter model. The geometries of the filter are generated by using SOLIDWORKS software and Computational Fluid Dynamics (CFD) software is used to analyse and simulates the flow through the filter. In this study, the parameters of the inlet velocity are 0.032 m/s, 0.063 m/s, 0.094 m/s and 0.126 m/s. The total pressure drop produce by basic, modified filter 1 and 2 is 292.3 Pa, 251.11 Pa and 274.7 Pa. The pressure drop reduction for the modified filter 1 is 41.19 Pa and 14.1% lower compared to basic filter and the pressure drop reduction for modified filter 2 is 17.6 Pa and 6.02% lower compared to the basic filter. The pressure drops for the basic filter are slightly different with the Salutary Avenue filter due to limited data and experiment details. CFD software are very reliable in running a simulation rather than produces the prototypes and conduct the experiment thus reducing overall time and cost in this study.

  6. Tissue fluid pressures - From basic research tools to clinical applications

    NASA Technical Reports Server (NTRS)

    Hargens, Alan R.; Akeson, Wayne H.; Mubarak, Scott J.; Owen, Charles A.; Gershuni, David H.

    1989-01-01

    This paper describes clinical applications of two basic research tools developed and refined in the past 20 years: the wick catheter (for measuring tissue fluid pressure) and the colloid osmometer (for measuring osmotic pressure). Applications of the osmometer include estimations of the reduced osmotic pressure of sickle-cell hemoglobin with deoxygenation, and of reduced swelling pressure of human nucleus pulposus with hydration or upon action of certain enzymes. Clinical uses of the wick-catheter technique include an improvement of diagnosis and treatment of acute and chronic compartment syndromes, the elucidation of the tissue pressure thresholds for neuromuscular dysfunction, and the development of a better tourniquet for orthopedics.

  7. Pake Prize: The Evolving Nature of Industrial Research

    NASA Astrophysics Data System (ADS)

    Compton, W. Dale

    2014-03-01

    The support of basic research in the physical sciences expanded rather quickly in the late 1950s and into the 1960s stimulated, in part, by the successful contribution of the scientific effort to the Second World War. Many in industry took on the challenge of creating research activities that focused on basic research. Many of these activities slowed in the 1970s and 1980s because of events in the economy and the marketplace. The challenges confronting the industrial research complexes were many. Retaining the high standards of quality in the research organization, encouraging partial realignment of programs to be more supportive of product lines and the various pressures arising from legislative measures to increase product efficiencies while reducing unwanted pollutants into the atmosphere, to name a few. Some of the highlights of the past 50 years will be reviewed using automotive industry examples. There will be another talk from Paul Grant for the next 36 minutes. I do not have his abstract yet but it has been requested.

  8. Hypertension, nitric oxide, oxidants, and dietary plant polyphenols.

    PubMed

    Galleano, Monica; Pechanova, Olga; Fraga, Cesar G

    2010-12-01

    Fruits and vegetables are key foods whose high ingestion is associated with the improvement of numerous pathological conditions, including hypertension. Such health promoting actions have been increasingly ascribed to the antioxidant characteristics of different polyphenols in fruits and vegetables. Consequently, based on this assumption, many beverages and foods rich in polyphenols, grape, tea, cocoa, and soy products and many of their chemical constituents purified, are being studied both, as antioxidants and antihypertensive agents. This paper reviews the current evidence linking high polyphenol consumption with reductions in blood pressure. Basic chemical aspects of flavanols, flavonols, isoflavones and stilbenes, as possible responsible for the observed effects of those foods on blood pressure are included. Human interventions studies by using grapes and wine, cocoa and chocolate, black and green tea, soy products, and purified compounds ((+)-catequin, quercetin, (-)-epigallocatechin gallate) are summarized. The discussed hypothesis, strongly supported by experimental data in animals, is that by regulating nitric oxide bioavailability, polyphenols present in fruits and vegetables affect endothelial function and as a consequence, blood pressure. Even when data are not definitive and many questions remain open, the whole evidence is encouraging to start considering diets that can provide a benefit to hypertensive subjects, and those benefits will be more significant in people that do not have controlled his/her elevated blood pressure.

  9. Study on Strata Behavior Regularity of 1301 Face in Thick Bedrock of Wei - qiang Coal Mine

    NASA Astrophysics Data System (ADS)

    Gu, Shuancheng; Yao, Boyu

    2017-09-01

    In order to ensure the safe and efficient production of the thick bedrock face, the rule of the strata behavior of the thick bedrock face is discussed through the observation of the strata pressure of the 1301 first mining face in Wei qiang coal mine. The initial face is to press the average distance of 50.75m, the periodic weighting is to press the average distance of 12.1m; during the normal mining period, although the upper roof can not be broken at the same time, but the pressure step is basically the same; the working face for the first weighting and periodical weighting is more obvious to the change of pressure step change, when the pressure of the working face is coming, the stent force increased significantly, but there are still part of the stent work resistance exceeds the rated working resistance, low stability, still need to strengthen management.

  10. Gas and plasma dynamics of RF discharge jet of low pressure in a vacuum chamber with flat electrodes and inside tube, influence of RF discharge on the steel surface parameters

    NASA Astrophysics Data System (ADS)

    Khristoliubova, V. I.; Kashapov, N. F.; Shaekhov, M. F.

    2016-06-01

    Researches results of the characteristics of the RF discharge jet of low pressure and the discharge influence on the surface modification of high speed and structural steels are introduced in the article. Gas dynamics, power and energy parameters of the RF low pressure discharge flow in the discharge chamber and the electrode gap are studied in the presence of the materials. Plasma flow rate, discharge power, the concentration of electrons, the density of RF power, the ion current density, and the energy of the ions bombarding the surface materials are considered for the definition of basic properties crucial for the process of surface modification of materials as they were put in the plasma jet. The influence of the workpiece and effect of products complex configuration on the RF discharge jet of low pressure is defined. The correlation of the input parameters of the plasma unit on the characteristics of the discharge is established.

  11. SPE (tm) water electrolyzers in support of mission from planet Earth

    NASA Technical Reports Server (NTRS)

    Mcelroy, J. F.

    1991-01-01

    During the 1970's, the Solid Polymer Electrolyte (SPE) water electrolyzer, which uses ion exchange membranes as its sole electrolyte, was developed for nuclear submarine metabolic oxygen production. SPE water electrolyzer developments included operation at up to 3,000 psia and at current densities in excess of 1,000 amps per square foot. The SPE water electrolyzer system has accumulated tens of thousands of system hours with the Navies of both the United States and the United Kingdom. During the 1980's, the basic SPE water electrolyzer cell structure developed for the Navies was incorporated into several demonstrators for NASA's Space Station Program. Among these were: (1) the SPE regenerative fuel cell for electrical energy storage; (2) the SPE water electrolyzer for metabolic oxygen production; and (3) the high pressure SPE water electrolyzer for reboost propellant production. In the 1990's, emphasis will be the development of SPE water electrolyzers for Mission from Planet Earth. Currently defined potential applications for the SPE water electrolyzer include: (1) SPE water electrolyzers operating at high pressure as part of a regenerative fuel cell extraterrestrial surface energy storage system; (2) SPE water electrolyzers for propellant production from extraterrestrial indigenous materials; and (3) SPE water electrolyzers for metabolic oxygen and potable water production from reclaimed water.

  12. Flame Atmospheric Pressure Chemical Ionization Coupled with Negative Electrospray Ionization Mass Spectrometry for Ion Molecule Reactions

    NASA Astrophysics Data System (ADS)

    Cheng, Sy-Chyi; Bhat, Suhail Muzaffar; Shiea, Jentaie

    2017-07-01

    Flame atmospheric pressure chemical ionization (FAPCI) combined with negative electrospray ionization (ESI) mass spectrometry was developed to detect the ion/molecule reactions (IMRs) products between nitric acid (HNO3) and negatively charged amino acid, angiotensin I (AI) and angiotensin II (AII), and insulin ions. Nitrate and HNO3-nitrate ions were detected in the oxyacetylene flame, suggesting that a large quantity of nitric acid (HNO3) was produced in the flame. The HNO3 and negatively charged analyte ions produced by a negative ESI source were delivered into each arm of a Y-shaped stainless steel tube where they merged and reacted. The products were subsequently characterized with an ion trap mass analyzer attached to the exit of the Y-tube. HNO3 showed the strongest affinity to histidine and formed (Mhistidine-H+HNO3)- complex ions, whereas some amino acids did not react with HNO3 at all. Reactions between HNO3 and histidine residues in AI and AII resulted in the formation of dominant [MAI-H+(HNO3)]- and [MAII-H+(HNO3)]- ions. Results from analyses of AAs and insulin indicated that HNO3 could not only react with basic amino acid residues, but also with disulfide bonds to form [M-3H+(HNO3)n]3- complex ions. This approach is useful for obtaining information about the number of basic amino acid residues and disulfide bonds in peptides and proteins.

  13. Flame Atmospheric Pressure Chemical Ionization Coupled with Negative Electrospray Ionization Mass Spectrometry for Ion Molecule Reactions.

    PubMed

    Cheng, Sy-Chyi; Bhat, Suhail Muzaffar; Shiea, Jentaie

    2017-07-01

    Flame atmospheric pressure chemical ionization (FAPCI) combined with negative electrospray ionization (ESI) mass spectrometry was developed to detect the ion/molecule reactions (IMRs) products between nitric acid (HNO 3 ) and negatively charged amino acid, angiotensin I (AI) and angiotensin II (AII), and insulin ions. Nitrate and HNO 3 -nitrate ions were detected in the oxyacetylene flame, suggesting that a large quantity of nitric acid (HNO 3 ) was produced in the flame. The HNO 3 and negatively charged analyte ions produced by a negative ESI source were delivered into each arm of a Y-shaped stainless steel tube where they merged and reacted. The products were subsequently characterized with an ion trap mass analyzer attached to the exit of the Y-tube. HNO 3 showed the strongest affinity to histidine and formed (M histidine -H+HNO 3 ) - complex ions, whereas some amino acids did not react with HNO 3 at all. Reactions between HNO 3 and histidine residues in AI and AII resulted in the formation of dominant [M AI -H+(HNO 3 )] - and [M AII -H+(HNO 3 )] - ions. Results from analyses of AAs and insulin indicated that HNO 3 could not only react with basic amino acid residues, but also with disulfide bonds to form [M-3H+(HNO 3 ) n ] 3- complex ions. This approach is useful for obtaining information about the number of basic amino acid residues and disulfide bonds in peptides and proteins. Graphical Abstract ᅟ.

  14. Increased nocturnal blood pressure in enuretic children with polyuria.

    PubMed

    Kruse, Anne; Mahler, Birgitte; Rittig, Soren; Djurhuus, Jens Christian

    2009-10-01

    We investigated the association between nocturnal blood pressure and urine production in children with enuresis. A total of 39 consecutive children with a mean age of 9.8 years (range 6.2 to 14.9) with monosymptomatic nocturnal enuresis completed a bladder diary, including 2 weeks of basic documentation and 2 with desmopressin titration from 120 to 240 microg sublingually. Arterial blood pressure was measured every 30 minutes during 24 hours and during 4 additional nights using an ambulatory blood pressure monitor. Furthermore, 10 healthy children were recruited into the study who completed a bladder diary for 5 days while measuring arterial blood pressures with documentation of all intake and voided volumes. Patients with nocturnal polyuria had significantly higher nocturnal mean arterial pressure than patients without polyuria and controls (p <0.05). Furthermore, a positive correlation was seen between nocturnal urine output and nocturnal mean arterial pressure (r = 0.32, p <0.001). Nocturnal urine output was significantly higher during wet nights than dry nights (p <0.001). However, no significant difference was found in mean arterial pressure between wet and dry nights. Nocturnal mean arterial pressure was significantly higher in children with enuresis with polyuria than in children without polyuria. There was a significant positive correlation between average nocturnal mean arterial pressure and nocturnal urine volume in the whole study. The association between nocturnal blood pressure and urine volume, and the role of blood pressure should be investigated in a larger group of children with enuresis who have nocturnal polyuria.

  15. A Basic Behavior of CNG DI Combustion in a Spark-Ignited Rapid Compression Machine

    NASA Astrophysics Data System (ADS)

    Huang, Zuohua; Shiga, Seiichi; Ueda, Takamasa; Jingu, Nobuhisa; Nakamura, Hisao; Ishima, Tsuneaki; Obokata, Tomio; Tsue, Mitsuhiro; Kono, Michikata

    A basic characteristics of compressed natural gas direct-injection (CNG DI) combustion was studied by using a rapid compression machine. Results show that comparing with homogeneous mixture, CNG DI has short combustion duration, high pressure rise due to combustion, and high rate of heat release, which are considered to come from the charge stratification and the gas flow generated by the fuel injection. CNG DI can realize extremely lean combustion which reaches 0.03 equivalence ratio, φ. Combustion duration, maximum pressure rise due to combustion and combustion efficiency are found to be insensitive to the injection modes. Unburned methane showed almost the same level as that of homogeneous mixture combustion. CO increased steeply with the increase in φ when φ was greater than 0.8 due to the excessive stratification, and NOx peak value shifted to the region of lower φ. Combustion inefficiency maintains less than 0.08 in the range of φ from 0.1 to 0.9 and increases at very low φ due to bulk quenching and at higher φ due to excessive stratification. The combustion efficiency estimated from combustion products shows good agreement with that of heat release analysis.

  16. Effectiveness of olive oil for the prevention of pressure ulcers caused in immobilized patients within the scope of primary health care: study protocol for a randomized controlled trial

    PubMed Central

    2013-01-01

    Background Pressure ulcers are considered an important issue, mainly affecting immobilized older patients. These pressure ulcers increase the care burden for the professional health service staff as well as pharmaceutical expenditure. There are a number of studies on the effectiveness of different products used for the prevention of pressure ulcers; however, most of these studies were carried out at a hospital level, basically using hyperoxygenated fatty acids (HOFA). There are no studies focused specifically on the use of olive-oil-based products and therefore this research is intended to find the most cost-effective treatment and achieve an alternative treatment. Methods/design The main objective is to assess the effectiveness of olive oil, comparing it with HOFA, to treat immobilized patients at home who are at risk of pressure ulcers. As a secondary objective, the cost-effectiveness balance of this new application with regard to the HOFA will be assessed. The study is designed as a noninferiority, triple-blinded, parallel, multi-center, randomized clinical trial. The scope of the study is the population attending primary health centers in Andalucía (Spain) in the regional areas of Malaga, Granada, Seville, and Cadiz. Immobilized patients at risk of pressure ulcers will be targeted. The target group will be treated by application of an olive-oil-based formula whereas the control group will be treated by application of HOFA to the control group. The follow-up period will be 16 weeks. The main variable will be the presence of pressure ulcers in the patient. Secondary variables include sociodemographic and clinical information, caregiver information, and whether technical support exists. Statistical analysis will include the Kolmogorov-Smirnov test, symmetry and kurtosis analysis, bivariate analysis using the Student’s t and chi-squared tests as well as the Wilcoxon and the Man-Whitney U tests, ANOVA and multivariate logistic regression analysis. Discussion The regular use of olive-oil-based formulas should be effective in preventing pressure ulcers in immobilized patients, thus leading to a more cost-effective product and an alternative treatment. Trial registration Clinicaltrials.gov identifier: NCT01595347. PMID:24152576

  17. Effectiveness of olive oil for the prevention of pressure ulcers caused in immobilized patients within the scope of primary health care: study protocol for a randomized controlled trial.

    PubMed

    Lupiáñez-Pérez, Inmaculada; Morilla-Herrera, Juan Carlos; Ginel-Mendoza, Leovigildo; Martín-Santos, Francisco Javier; Navarro-Moya, Francisco Javier; Sepúlveda-Guerra, Rafaela Pilar; Vázquez-Cerdeiros, Rosa; Cuevas-Fernández-Gallego, Magdalena; Benítez-Serrano, Isabel María; Lupiáñez-Pérez, Yolanda; Morales-Asencio, José Miguel

    2013-10-23

    Pressure ulcers are considered an important issue, mainly affecting immobilized older patients. These pressure ulcers increase the care burden for the professional health service staff as well as pharmaceutical expenditure. There are a number of studies on the effectiveness of different products used for the prevention of pressure ulcers; however, most of these studies were carried out at a hospital level, basically using hyperoxygenated fatty acids (HOFA). There are no studies focused specifically on the use of olive-oil-based products and therefore this research is intended to find the most cost-effective treatment and achieve an alternative treatment. The main objective is to assess the effectiveness of olive oil, comparing it with HOFA, to treat immobilized patients at home who are at risk of pressure ulcers. As a secondary objective, the cost-effectiveness balance of this new application with regard to the HOFA will be assessed. The study is designed as a noninferiority, triple-blinded, parallel, multi-center, randomized clinical trial. The scope of the study is the population attending primary health centers in Andalucía (Spain) in the regional areas of Malaga, Granada, Seville, and Cadiz. Immobilized patients at risk of pressure ulcers will be targeted. The target group will be treated by application of an olive-oil-based formula whereas the control group will be treated by application of HOFA to the control group. The follow-up period will be 16 weeks. The main variable will be the presence of pressure ulcers in the patient. Secondary variables include sociodemographic and clinical information, caregiver information, and whether technical support exists. Statistical analysis will include the Kolmogorov-Smirnov test, symmetry and kurtosis analysis, bivariate analysis using the Student's t and chi-squared tests as well as the Wilcoxon and the Man-Whitney U tests, ANOVA and multivariate logistic regression analysis. The regular use of olive-oil-based formulas should be effective in preventing pressure ulcers in immobilized patients, thus leading to a more cost-effective product and an alternative treatment. Clinicaltrials.gov identifier: NCT01595347.

  18. Effect of Exit-Slot Position and Opening on the Available Cooling Pressure for NACA Nose-Slot Cowlings

    NASA Technical Reports Server (NTRS)

    Stickle, George W; Naiman, Irven; Crigler, John L

    1940-01-01

    Report presents the results of an investigation of full-scale nose-slot cowlings conducted in the NACA 20-foot wind tunnel to furnish information on the pressure drop available for cooling. Engine conductances from 0 to 0.12 and exit-slot conductances from 0 to 0.30 were covered. Two basic nose shapes were tested to determine the effect of the radius of curvature of the nose contour; the nose shape with the smaller radius of curvature gave the higher pressure drop across the engine. The best axial location of the slot for low-speed operation was found to be in the region of maximum negative pressure for the basic shape for the particular operating condition. The effect of the pressure operating condition on the available cooling pressure is shown.

  19. Supercritical transitiometry of polymers.

    PubMed

    Randzio, S L; Grolier, J P

    1998-06-01

    Employing supercritical fluids (SCFs) during polymers processing allows the unusual properties of SCFs to be exploited for making polymer products that cannot be obtained by other means. A new supercritical transitiometer has been constructed to permit study of the interactions of SCFs with polymers during processing under well-defined conditions of temperature and pressure. The supercritical transitiometer allows pressure to be exerted by either a supercritical fluid or a neutral medium and enables simultaneous determination of four basic parameters of a transition, i.e., p, T, Δ(tr)H and Δ(tr)V. This permits determination of the SCF effect on modification of the polymer structure at a given pressure and temperature and defines conditions to allow reproducible preparation of new polymer structures. Study of a semicrystalline polyethylene by this method has defined conditions for preparation of new microfoamed phases with good mechanical properties. The low densities and microporous structures of the new materials may make them useful for applications in medicine, pharmacy, or the food industry, for example.

  20. Efficient green methanol synthesis from glycerol

    NASA Astrophysics Data System (ADS)

    Haider, Muhammad H.; Dummer, Nicholas F.; Knight, David W.; Jenkins, Robert L.; Howard, Mark; Moulijn, Jacob; Taylor, Stuart H.; Hutchings, Graham J.

    2015-12-01

    The production of biodiesel from the transesterification of plant-derived triglycerides with methanol has been commercialized extensively. Impure glycerol is obtained as a by-product at roughly one-tenth the mass of the biodiesel. Utilization of this crude glycerol is important in improving the viability of the overall process. Here we show that crude glycerol can be reacted with water over very simple basic or redox oxide catalysts to produce methanol in high yields, together with other useful chemicals, in a one-step low-pressure process. Our discovery opens up the possibility of recycling the crude glycerol produced during biodiesel manufacture. Furthermore, we show that molecules containing at least two hydroxyl groups can be converted into methanol, which demonstrates some aspects of the generality of this new chemistry.

  1. Matrix exponential-based closures for the turbulent subgrid-scale stress tensor.

    PubMed

    Li, Yi; Chevillard, Laurent; Eyink, Gregory; Meneveau, Charles

    2009-01-01

    Two approaches for closing the turbulence subgrid-scale stress tensor in terms of matrix exponentials are introduced and compared. The first approach is based on a formal solution of the stress transport equation in which the production terms can be integrated exactly in terms of matrix exponentials. This formal solution of the subgrid-scale stress transport equation is shown to be useful to explore special cases, such as the response to constant velocity gradient, but neglecting pressure-strain correlations and diffusion effects. The second approach is based on an Eulerian-Lagrangian change of variables, combined with the assumption of isotropy for the conditionally averaged Lagrangian velocity gradient tensor and with the recent fluid deformation approximation. It is shown that both approaches lead to the same basic closure in which the stress tensor is expressed as the matrix exponential of the resolved velocity gradient tensor multiplied by its transpose. Short-time expansions of the matrix exponentials are shown to provide an eddy-viscosity term and particular quadratic terms, and thus allow a reinterpretation of traditional eddy-viscosity and nonlinear stress closures. The basic feasibility of the matrix-exponential closure is illustrated by implementing it successfully in large eddy simulation of forced isotropic turbulence. The matrix-exponential closure employs the drastic approximation of entirely omitting the pressure-strain correlation and other nonlinear scrambling terms. But unlike eddy-viscosity closures, the matrix exponential approach provides a simple and local closure that can be derived directly from the stress transport equation with the production term, and using physically motivated assumptions about Lagrangian decorrelation and upstream isotropy.

  2. Effects of Cations on Corrosion of Inconel 625 in Molten Chloride Salts

    NASA Astrophysics Data System (ADS)

    Zhu, Ming; Ma, Hongfang; Wang, Mingjing; Wang, Zhihua; Sharif, Adel

    2016-04-01

    Hot corrosion of Inconel 625 in sodium chloride, potassium chloride, magnesium chloride, calcium chloride and their mixtures with different compositions is conducted at 900°C to investigate the effects of cations in chloride salts on corrosion behavior of the alloy. XRD, SEM/EDS were used to analyze the compositions, phases, and morphologies of the corrosion products. The results showed that Inconel 625 suffers more severe corrosion in alkaline earth metal chloride molten salts than alkaline metal chloride molten salts. For corrosion in mixture salts, the corrosion rate increased with increasing alkaline earth metal chloride salt content in the mixture. Cations in the chloride molten salts mainly affect the thermal and chemical properties of the salts such as vapor pressure and hydroscopicities, which can affect the basicity of the molten salt. Corrosion of Inconel 625 in alkaline earth metal chloride salts is accelerated with increasing basicity.

  3. Guide for certifying pressure vessels and systems

    NASA Technical Reports Server (NTRS)

    Lundy, Floyd; Krusa, Paul W.

    1992-01-01

    This guide is intended to provide methodology and describe the intent of the Pressure Vessel and System (PV/S) Certification program. It is not meant to be a mandated document, but is intended to transmit a basic understanding of the PV/S program, and include examples. After the reader has familiarized himself with this publication, he should have a basic understanding of how to go about developing a PV/S certification program.

  4. Boosting the value of biodiesel byproduct by the non-catalytic transesterification of dimethyl carbonate via a continuous flow system under ambient pressure.

    PubMed

    Kwon, Eilhann E; Yi, Haakrho; Jeon, Young Jae

    2014-10-01

    Transformation of coconut oil into biodiesel by using dimethyl carbonate (DMC) via a non-catalytic transesterification reaction under ambient pressure was investigated in this study. The non-catalytic transformation to biodiesel was achieved by means of a heterogeneous reaction between liquid triglycerides and gas phase DMC. The reaction was enhanced in the presence of porous material due to its intrinsic physical properties such as tortuosity and absorption/adsorption. The numerous pores in the material served as micro reaction chambers and ensured that there was enough contact time between the liquid triglycerides and the gaseous DMC, which enabled the completion of the transesterification. The highest fatty acid methyl esters (FAMEs) yield achieved was 98±0.5% within 1-2min at a temperature of 360-450°C under ambient pressure. The fast reaction rates made it possible to convert the lipid feedstock into biodiesel via a continuous flow system without the application of increased pressure. This suggested that the commonly used supercritical conditions could be avoided, resulting in huge cost benefits for biodiesel production. In addition, the high value of the byproduct from the transesterification of the lipid feedstock with DMC suggested that the production biodiesel using this method could be more economically competitive. Finally, the basic properties of biodiesel derived from the non-catalytic conversion of rapeseed oil with DMC were summarised. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Industrial waste utilization in the panels production for high buildings facade and socle facing

    NASA Astrophysics Data System (ADS)

    Vitkalova, Irina; Torlova, Anastasiya; Pikalov, Evgeniy; Selivanov, Oleg

    2018-03-01

    The research presents comprehensive utilization of such industrial waste as galvanic sludge, broken window glass as functional additives for producing ceramics for facade and socle paneling in high-rise construction. The basic charge component is low-plasticity clay, which does not allow producing high-quality products if used without any functional additives. The application of the mentioned above components broadens the resource base, reduces production cost and the mass of the products in comparison with the currently used facing ceramics. The decrease of product mass helps to reduce the load on the basement and to use ceramic material in high-rise construction more effectively. Additional advantage of the developed composition is the reducing of production energy intensity due to comparatively low pressing pressure and firing temperature thus reducing the overall production cost. The research demonstrates the experimental results of determining density, compressive strength, water absorption, porosity and frost resistance of the produced ceramic material. These characteristics prove that the material can be applied for high buildings outdoor paneling. Additional research results prove ecologic safety of the produced ceramic material.

  6. Setting the Pressure at Which to Conduct a Distillation.

    ERIC Educational Resources Information Center

    Barduhn, Allen J.

    1984-01-01

    Discusses how pressure setting is determined for distillation columns, examining factors which must be considered when optimizing design for economical balance. Also discusses the basics of heat exchangers and cites a common problem with pressure differences. (JM)

  7. Low-Cost High-Pressure Hydrogen Generator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cropley, Cecelia C.; Norman, Timothy J.

    Electrolysis of water, particularly in conjunction with renewable energy sources, is potentially a cost-effective and environmentally friendly method of producing hydrogen at dispersed forecourt sites, such as automotive fueling stations. The primary feedstock for an electrolyzer is electricity, which could be produced by renewable sources such as wind or solar that do not produce carbon dioxide or other greenhouse gas emissions. However, state-of-the-art electrolyzer systems are not economically competitive for forecourt hydrogen production due to their high capital and operating costs, particularly the cost of the electricity used by the electrolyzer stack. In this project, Giner Electrochemical Systems, LLC (GES)more » developed a low cost, high efficiency proton-exchange membrane (PEM) electrolysis system for hydrogen production at moderate pressure (300 to 400 psig). The electrolyzer stack operates at differential pressure, with hydrogen produced at moderate pressure while oxygen is evolved at near-atmospheric pressure, reducing the cost of the water feed and oxygen handling subsystems. The project included basic research on catalysts and membranes to improve the efficiency of the electrolysis reaction as well as development of advanced materials and component fabrication methods to reduce the capital cost of the electrolyzer stack and system. The project culminated in delivery of a prototype electrolyzer module to the National Renewable Energy Laboratory for testing at the National Wind Technology Center. Electrolysis cell efficiency of 72% (based on the lower heating value of hydrogen) was demonstrated using an advanced high-strength membrane developed in this project. This membrane would enable the electrolyzer system to exceed the DOE 2012 efficiency target of 69%. GES significantly reduced the capital cost of a PEM electrolyzer stack through development of low cost components and fabrication methods, including a 60% reduction in stack parts count. Economic analysis indicates that hydrogen could be produced for $3.79 per gge at an electricity cost of $0.05/kWh by the lower-cost PEM electrolyzer developed in this project, assuming high-volume production of large-scale electrolyzer systems.« less

  8. On the mechanism of self gravitating Rossby interfacial waves in proto-stellar accretion discs

    NASA Astrophysics Data System (ADS)

    Yellin-Bergovoy, Ron; Heifetz, Eyal; Umurhan, Orkan M.

    2016-05-01

    The dynamical response of edge waves under the influence of self-gravity is examined in an idealised two-dimensional model of a proto-stellar disc, characterised in steady state as a rotating vertically infinite cylinder of fluid with constant density except for a single density interface at some radius ?. The fluid in basic state is prescribed to rotate with a Keplerian profile ? modified by some additional azimuthal sheared flow. A linear analysis shows that there are two azimuthally propagating edge waves, kin to the familiar Rossby waves and surface gravity waves in terrestrial studies, which move opposite to one another with respect to the local basic state rotation rate at the interface. Instability only occurs if the radial pressure gradient is opposite to that of the density jump (unstably stratified) where self-gravity acts as a wave stabiliser irrespective of the stratification of the system. The propagation properties of the waves are discussed in detail in the language of vorticity edge waves. The roles of both Boussinesq and non-Boussinesq effects upon the stability and propagation of these waves with and without the inclusion of self-gravity are then quantified. The dynamics involved with self-gravity non-Boussinesq effect is shown to be a source of vorticity production where there is a jump in the basic state density In addition, self-gravity also alters the dynamics via the radial main pressure gradient, which is a Boussinesq effect. Further applications of these mechanical insights are presented in the conclusion including the ways in which multiple density jumps or gaps may or may not be stable.

  9. Technology advancement of the static feed water electrolysis process

    NASA Technical Reports Server (NTRS)

    Schubert, F. H.; Wynveen, R. A.

    1977-01-01

    A program to advance the technology of oxygen- and hydrogen-generating subsystems based on water electrolysis was studied. Major emphasis was placed on static feed water electrolysis, a concept characterized by low power consumption and high intrinsic reliability. The static feed based oxygen generation subsystem consists basically of three subassemblies: (1) a combined water electrolysis and product gas dehumidifier module; (2) a product gas pressure controller and; (3) a cyclically filled water feed tank. Development activities were completed at the subsystem as well as at the component level. An extensive test program including single cell, subsystem and integrated system testing was completed with the required test support accessories designed, fabricated, and assembled. Mini-product assurance activities were included throughout all phases of program activities. An extensive number of supporting technology studies were conducted to advance the technology base of the static feed water electrolysis process and to resolve problems.

  10. Strategic marketing, part 2: the 4 P's of marketing.

    PubMed

    Lexa, Frank James; Berlin, Jonathan

    2006-04-01

    Marketing and branding are critical business functions that are often ignored or misapplied in the health care sector. Radiology professionals are facing unprecedented competition, turf battles, and other pressures. One tool that can help in meeting this onslaught is to improve your marketing efforts. Some of the most expensive mistakes in marketing (medical and otherwise) are caused by not paying attention to the basics. These "rookie" errors can be avoided by a careful review of the 4 key principles of introductory marketing: product, price, placement, and promotion. This article reviews these concepts as they relate to medical marketing.

  11. Space Shuttle Orbiter oxygen partial pressure sensing and control system improvements

    NASA Technical Reports Server (NTRS)

    Frampton, Robert F.; Hoy, Dennis M.; Kelly, Kevin J.; Walleshauser, James J.

    1992-01-01

    A program aimed at developing a new PPO2 oxygen sensor and a replacement amplifier for the Space Shuttle Orbiter is described. Experimental design methodologies used in the test and modeling process made it possible to enhance the effectiveness of the program and to reduce its cost. Significant cost savings are due to the increased lifetime of the basic sensor cell, the maximization of useful sensor life through an increased amplifier gain adjustment capability, the use of streamlined production processes for the manufacture of the assemblies, and the refurbishment capability of the replacement sensor.

  12. Development of Wing Inlets

    NASA Technical Reports Server (NTRS)

    Racisz, Stanley F.

    1946-01-01

    Lift, drag, internal flow, and pressure distribution measurements were made on a low-drag airfoil incorporating various air inlet designs. Two leading-edge air inlets are developed which feature higher lift coefficients and critical Mach than the basic airfoil. Higher lift coefficients and critical speeds are obtained for leading half of these inlet sections but because of high suction pressures near exist, slightly lower critical speeds are obtained for the entire inlet section than the basic airfoil.

  13. 48 CFR 252.216-7000 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products. 252.216-7000 Section 252.216-7000 Federal... adjustment—basic steel, aluminum, brass, bronze, or copper mill products. As prescribed in 216.203-4-70(a)(1), use the following clause: Economic Price Adjustment—Basic Steel, Aluminum, Brass, Bronze, or Copper...

  14. 48 CFR 252.216-7000 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products. 252.216-7000 Section 252.216-7000 Federal... adjustment—basic steel, aluminum, brass, bronze, or copper mill products. As prescribed in 216.203-4-70(a)(1), use the following clause: Economic Price Adjustment—Basic Steel, Aluminum, Brass, Bronze, or Copper...

  15. 48 CFR 252.216-7000 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products. 252.216-7000 Section 252.216-7000 Federal... adjustment—basic steel, aluminum, brass, bronze, or copper mill products. As prescribed in 216.203-4-70(a)(1), use the following clause: Economic Price Adjustment—Basic Steel, Aluminum, Brass, Bronze, or Copper...

  16. 48 CFR 252.216-7000 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products. 252.216-7000 Section 252.216-7000 Federal... adjustment—basic steel, aluminum, brass, bronze, or copper mill products. As prescribed in 216.203-4-70(a), use the following clause: Economic Price Adjustment—Basic Steel, Aluminum, Brass, Bronze, or Copper...

  17. Upgrade to the Cryogenic Hydrogen Gas Target Monitoring System

    NASA Astrophysics Data System (ADS)

    Slater, Michael; Tribble, Robert

    2013-10-01

    The cryogenic hydrogen gas target at Texas A&M is a vital component for creating a secondary radioactive beam that is then used in experiments in the Momentum Achromat Recoil Spectrometer (MARS). A stable beam from the K500 superconducting cyclotron enters the gas cell and some incident particles are transmuted by a nuclear reaction into a radioactive beam, which are separated from the primary beam and used in MARS experiments. The pressure in the target chamber is monitored so that a predictable isotope production rate can be assured. A ``black box'' received the analog pressure data and sent RS232 serial data through an outdated serial connection to an outdated Visual Basic 6 (VB6) program, which plotted the chamber pressure continuously. The black box has been upgraded to an Arduino UNO microcontroller [Atmel Inc.], which can receive the pressure data and output via USB to a computer. It has been programmed to also accept temperature data for future upgrade. A new computer program, with updated capabilities, has been written in Python. The software can send email alerts, create audible alarms through the Arduino, and plot pressure and temperature. The program has been designed to better fit the needs of the users. Funded by DOE and NSF-REU Program.

  18. Development of processes for the production of solar grade silicon from halides and alkali metals, phase 1 and phase 2

    NASA Technical Reports Server (NTRS)

    Dickson, C. R.; Gould, R. K.; Felder, W.

    1981-01-01

    High temperature reactions of silicon halides with alkali metals for the production of solar grade silicon are described. Product separation and collection processes were evaluated, measure heat release parameters for scaling purposes and effects of reactants and/or products on materials of reactor construction were determined, and preliminary engineering and economic analysis of a scaled up process were made. The feasibility of the basic process to make and collect silicon was demonstrated. The jet impaction/separation process was demonstrated to be a purification process. The rate at which gas phase species from silicon particle precursors, the time required for silane decomposition to produce particles, and the competing rate of growth of silicon seed particles injected into a decomposing silane environment were determined. The extent of silane decomposition as a function of residence time, temperature, and pressure was measured by infrared absorption spectroscopy. A simplistic model is presented to explain the growth of silicon in a decomposing silane enviroment.

  19. Pressure ulcers: Back to the basics

    PubMed Central

    Agrawal, Karoon; Chauhan, Neha

    2012-01-01

    Pressure ulcer in an otherwise sick patient is a matter of concern for the care givers as well as the medical personnel. A lot has been done to understand the disease process. So much so that USA and European countries have established advisory panels in their respective continents. Since the establishment of these organizations, the understanding of the pressure ulcer has improved significantly. The authors feel that the well documented and well publicized definition of pressure ulcer is somewhat lacking in the correct description of the disease process. Hence, a modified definition has been presented. This disease is here to stay. In the process of managing these ulcers the basic pathology needs to be understood well. Pressure ischemia is the main reason behind the occurrence of ulceration. Different extrinsic and intrinsic factors have been described in detail with review of literature. There are a large number of risk factors causing ulceration. The risk assessment scales have eluded the surgical literature and mostly remained in nursing books and websites. These scales have been reproduced for completion of the basics on decubitus ulcer. The classification of the pressure sores has been given in a comparative form to elucidate that most of the classifications are the same except for minor variations. The management of these ulcers is ever evolving but the age old saying of “prevention is better than cure” suits this condition the most. PMID:23162223

  20. Non-linear optical techniques and optical properties of condensed molecular systems

    NASA Astrophysics Data System (ADS)

    Citroni, Margherita

    2013-06-01

    Structure, dynamics, and optical properties of molecular systems can be largely modified by the applied pressure, with remarkable consequences on their chemical stability. Several examples of selective reactions yielding technologically attractive products can be cited, which are particularly efficient when photochemical effects are exploited in conjunction with the structural conditions attained at high density. Non-linear optical techniques are a basic tool to unveil key aspects of the chemical reactivity and dynamic properties of molecules. Their application to high-pressure samples is experimentally challenging, mainly because of the small sample dimensions and of the non-linear effects generated in the anvil materials. In this talk I will present results on the electronic spectra of several aromatic crystals obtained through two-photon induced fluorescence and two-photon excitation profiles measured as a function of pressure (typically up to about 25 GPa), and discuss the relationship between the pressure-induced modifications of the electronic structure and the chemical reactivity at high pressure. I will also present the first successful pump-probe infrared measurement performed as a function of pressure on a condensed molecular system. The system under examination is liquid water, in a sapphire anvil cell, up to 1 GPa along isotherms at 298 and 363 K. These measurements give a new enlightening insight into the dynamical properties of low- and high-density water allowing a definition of the two structures.

  1. Numerical study on self-cleaning canister filter with modified filter cap

    NASA Astrophysics Data System (ADS)

    Mohammed, Akmal Nizam; Zolkhaely, Mohd Hafiz; Sahrudin, Mohd Sahrizan; Razali, Mohd Azahari; Sapit, Azwan; Hushim, Mohd Faisal

    2017-04-01

    Air filtration system plays an important role in getting good quality air into turbo machinery such as gas turbine. The filtration system and filters improve the quality of air and protect the gas turbine parts from contaminants which could bring damage. This paper is focused on the configuration of the self-cleaning canister filter in order to obtain the minimal pressure drop along the filter. The configuration includes a modified canister filter cap that is based on the basic geometry that conforms to industry standard. This paper describes the use of CFD to simulate and analyze the flow through the filter. This tool is also used to monitor variables such as pressure and velocity along the filter and to visualize them in the form of contours, vectors and streamlines. In this study, the main parameter varied is the inlet velocity set in the boundary condition during simulations, which are 0.032, 0.063, 0.094 and 0.126 m/s respectively. The data obtained from simulations are then validated with reference data sourced from the industry, and comparisons have subsequently been made for these two filters. As a result, the improvement of the pressure drop for the modified filter is found to be 11.47% to 14.82% compared to the basic filter at the inlet velocity from 0.032 to 0.126 m/s. the total pressure drop produced is 292.3 Pa by the basic filter and 251.11 Pa for modified filter. The pressure drop reduction is 41.19 Pa, which is 14.1% from the basic filter.

  2. The Future of Basic Science in Academic Surgery: Identifying Barriers to Success for Surgeon-scientists.

    PubMed

    Keswani, Sundeep G; Moles, Chad M; Morowitz, Michael; Zeh, Herbert; Kuo, John S; Levine, Matthew H; Cheng, Lily S; Hackam, David J; Ahuja, Nita; Goldstein, Allan M

    2017-06-01

    The aim of this study was to examine the challenges confronting surgeons performing basic science research in today's academic surgery environment. Multiple studies have identified challenges confronting surgeon-scientists and impacting their ability to be successful. Although these threats have been known for decades, the downward trend in the number of successful surgeon-scientists continues. Clinical demands, funding challenges, and other factors play important roles, but a rigorous analysis of academic surgeons and their experiences regarding these issues has not previously been performed. An online survey was distributed to 2504 members of the Association for Academic Surgery and Society of University Surgeons to determine factors impacting success. Survey results were subjected to statistical analyses. We also reviewed publicly available data regarding funding from the National Institutes of Health (NIH). NIH data revealed a 27% decline in the proportion of NIH funding to surgical departments relative to total NIH funding from 2007 to 2014. A total of 1033 (41%) members responded to our survey, making this the largest survey of academic surgeons to date. Surgeons most often cited the following factors as major impediments to pursuing basic investigation: pressure to be clinically productive, excessive administrative responsibilities, difficulty obtaining extramural funding, and desire for work-life balance. Surprisingly, a majority (68%) did not believe surgeons can be successful basic scientists in today's environment, including departmental leadership. We have identified important barriers that confront academic surgeons pursuing basic research and a perception that success in basic science may no longer be achievable. These barriers need to be addressed to ensure the continued development of future surgeon-scientists.

  3. Effect of chest compressions only during experimental basic life support on alveolar collapse and recruitment.

    PubMed

    Markstaller, Klaus; Rudolph, Annette; Karmrodt, Jens; Gervais, Hendrik W; Goetz, Rolf; Becher, Anja; David, Matthias; Kempski, Oliver S; Kauczor, Hans-Ulrich; Dick, Wolfgang F; Eberle, Balthasar

    2008-10-01

    The importance of ventilatory support during cardiac arrest and basic life support is controversial. This experimental study used dynamic computed tomography (CT) to assess the effects of chest compressions only during cardiopulmonary resuscitation (CCO-CPR) on alveolar recruitment and haemodynamic parameters in porcine model of ventricular fibrillation. Twelve anaesthetized pigs (26+/-1 kg) were randomly assigned to one of the following groups: (1) intermittent positive pressure ventilation (IPPV) both during basic life support and advanced cardiac life support, or (2) CCO during basic life support and IPPV during advanced cardiac life support. Measurements were acquired at baseline prior to cardiac arrest, during basic life support, during advanced life support, and after return of spontaneous circulation (ROSC), as follows: dynamic CT series, arterial and central venous pressures, blood gases, and regional organ blood flow. The ventilated and atelectatic lung area was quantified from dynamic CT images. Differences between groups were analyzed using the Kruskal-Wallis test, and a p<0.05 was considered statistically significant. IPPV was associated with cyclic alveolar recruitment and de-recruitment. Compared with controls, the CCO-CPR group had a significantly larger mean fractional area of atelectasis (p=0.009), and significantly lower PaO2 (p=0.002) and mean arterial pressure (p=0.023). The increase in mean atelectatic lung area observed during basic life support in the CCO-CPR group remained clinically relevant throughout the subsequent advanced cardiac life support period and following ROSC, and was associated with prolonged impaired haemodynamics. No inter-group differences in myocardial and cerebral blood flow were observed. A lack of ventilation during basic life support is associated with excessive atelectasis, arterial hypoxaemia and compromised CPR haemodynamics. Moreover, these detrimental effects remain evident even after restoration of IPPV.

  4. Basic science faculty in surgical departments: advantages, disadvantages and opportunities.

    PubMed

    Chinoy, Mala R; Moskowitz, Jay; Wilmore, Douglas W; Souba, Wiley W

    2005-01-01

    The number of Ph.D. faculty in clinical departments now exceeds the number of Ph.D. faculty in basic science departments. Given the escalating pressures on academic surgeons to produce in the clinical arena, the recruitment and retention of high-quality Ph.D.s will become critical to the success of an academic surgical department. This success will be as dependent on the surgical faculty understanding the importance of the partnership as the success of the Ph.D. investigator. Tighter alignment among the various clinical and research programs and between surgeons and basic scientists will facilitate the generation of new knowledge that can be translated into useful products and services (thus improving care). To capitalize on what Ph.D.s bring to the table, surgery departments may need to establish a more formal research infrastructure that encourages the ongoing exchange of ideas and resources. Physically removing barriers between the research groups, encouraging the open exchange of techniques and observations and sharing core laboratories is characteristic of successful research teams. These strategies can meaningfully contribute to developing successful training program grants, program projects and bringing greater research recognition to the department of surgery.

  5. 48 CFR 252.216-7000 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products. 252.216-7000 Section 252.216-7000 Federal... adjustment—basic steel, aluminum, brass, bronze, or copper mill products. As prescribed in 216.203-4-70(a... Mill Products (JUL 1997) (a) Definitions. As used in this clause— Established price means a price which...

  6. Improved egg crack detection algorithm for modified pressure imaging system

    USDA-ARS?s Scientific Manuscript database

    Shell eggs with microcracks are often undetected during egg grading processes. In the past, a modified pressure imaging system was developed to detect eggs with microcracks without adversely affecting the quality of normal intact eggs. The basic idea of the modified pressure imaging system was to ap...

  7. Western Shallow Oil Zone, Elk Hills Field, Kern County, California:

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carey, K.B.

    1987-09-01

    The general Reservoir Study of the Western Shallow Oil Zone was prepared by Evans, Carey and Crozier as Task Assignment 009 with the United States Department of Energy. This study, Appendix II addresses the first Wilhelm Sands and its sub unites and pools. Basic pressure, production and assorted technical data were provided by the US Department of Energy staff at Elk Hills. These data were accepted as furnished with no attempt being made by Evans, Carey and Crozier for independent verification. This study has identified the petrophysical properties and the past productive performance of the reservoir. Primary reserves have beenmore » determined and general means of enhancing future recovery have been suggested. It is hoped that this volume can now additionally serve as a take off point for exploitation engineers to develop specific programs toward the end.« less

  8. FoilSim: Basic Aerodynamics Software Created

    NASA Technical Reports Server (NTRS)

    Peterson, Ruth A.

    1999-01-01

    FoilSim is interactive software that simulates the airflow around various shapes of airfoils. The graphical user interface, which looks more like a video game than a learning tool, captures and holds the students interest. The software is a product of NASA Lewis Research Center s Learning Technologies Project, an educational outreach initiative within the High Performance Computing and Communications Program (HPCCP).This airfoil view panel is a simulated view of a wing being tested in a wind tunnel. As students create new wing shapes by moving slider controls that change parameters, the software calculates their lift. FoilSim also displays plots of pressure or airspeed above and below the airfoil surface.

  9. Basic Study on Production Well Integrity for Methane Hydrate Development

    NASA Astrophysics Data System (ADS)

    Kakumoto, M.; Yoneda, J.; Katagiri, J.; Tenma, N.; Aoki, K.

    2014-12-01

    Methane Hydrate (MH) exist as an ice-like crystal under low-temperature and high-pressure condition, and it has gathering attention as a non-conventional natural gas resource. Depressurization method is a method to reduce the bottom hole pressure by submersible pump lowering water level in the production well, and gas and water is recovered by MH dissociation at the in situ. During the depressurization operation, consolidation and deformation of sediment occurs because of increase of effective stress by depressurization and changes in the soil structure by MH dissociation. Then consolidation and deformation of sediment makes negative friction between the production well and sediment, and large stress is occur in casing. Therefore there is concern that it may cause compression failure and shear failure of the production well. For safe MH development, it is necessary to grasp the deformation and stress vicinity of the production well. At first, we conducted push-out test to get friction strength between the different materials simulated the well and sediment. And we have done numerical analysis for integrity using by these data. The results of numerical analysis showed that the large deformation of sediment occur around the depressurization zone, and for the well, the large tensile stress in the vertical direction occur the upper vicinity of the depressurization zone.This study was financially supported by the Research Consortium for Methane Hydrate Resources in Japan (MH21 Research Consortium) planned by Ministry of Economy, Trade and Industry (METI). The authors thank the entire personnel related to MH21 Research Consortium.

  10. Measurement Corner: Volume, Temperature and Pressure

    ERIC Educational Resources Information Center

    Teates, Thomas G.

    1977-01-01

    Boyle's Law and basic relationships between volume and pressure of a gas at constant temperature are presented. Suggests two laboratory activities for demonstrating the effect of temperature on the volume of a gas or liquid. (CS)

  11. 48 CFR 252.216-7007 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products-representation. 252.216-7007 Section 252....216-7007 Economic price adjustment—basic steel, aluminum, brass, bronze, or copper mill products... Steel, Aluminum, Brass, Bronze, or Copper Mill Products—Representation (MAR 2012) (a) Definitions. The...

  12. 48 CFR 252.216-7007 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products-representation. 252.216-7007 Section 252....216-7007 Economic price adjustment—basic steel, aluminum, brass, bronze, or copper mill products... Steel, Aluminum, Brass, Bronze, or Copper Mill Products—Representation (MAR 2012) (a) Definitions. The...

  13. 48 CFR 252.216-7007 - Economic price adjustment-basic steel, aluminum, brass, bronze, or copper mill products...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-basic steel, aluminum, brass, bronze, or copper mill products-representation. 252.216-7007 Section 252....216-7007 Economic price adjustment—basic steel, aluminum, brass, bronze, or copper mill products... Steel, Aluminum, Brass, Bronze, or Copper Mill Products—Representation (MAR 2012) (a) Definitions. The...

  14. Experimental and Computational Studies of Molecular and Lattice Symmetries of Energetic Materials at High Pressure

    DTIC Science & Technology

    2002-01-01

    Prescribed by ANSI Std Z39-18 Research and Technology Department Dynamics and Diagnostics Division, Static High- Pressure Group Overall Research...Department Dynamics and Diagnostics Division, Static High- Pressure Group Impact of this Basic Research • This research generates phase and density...Static High- Pressure Group Experimental Methodology Use Diamond Anvil Cells (DAC) with coil Heaters (HDAC) to achieve • High pressures (P) to 10 GPa

  15. Basic Nuclear Physics.

    ERIC Educational Resources Information Center

    Bureau of Naval Personnel, Washington, DC.

    Basic concepts of nuclear structures, radiation, nuclear reactions, and health physics are presented in this text, prepared for naval officers. Applications to the area of nuclear power are described in connection with pressurized water reactors, experimental boiling water reactors, homogeneous reactor experiments, and experimental breeder…

  16. The Future of Basic Science in Academic Surgery

    PubMed Central

    Keswani, Sundeep G.; Moles, Chad M.; Morowitz, Michael; Zeh, Herbert; Kuo, John S.; Levine, Matthew H.; Cheng, Lily S.; Hackam, David J.; Ahuja, Nita; Goldstein, Allan M.

    2017-01-01

    Objective The aim of this study was to examine the challenges confronting surgeons performing basic science research in today’s academic surgery environment. Summary of Background Data Multiple studies have identified challenges confronting surgeon-scientists and impacting their ability to be successful. Although these threats have been known for decades, the downward trend in the number of successful surgeon-scientists continues. Clinical demands, funding challenges, and other factors play important roles, but a rigorous analysis of academic surgeons and their experiences regarding these issues has not previously been performed. Methods An online survey was distributed to 2504 members of the Association for Academic Surgery and Society of University Surgeons to determine factors impacting success. Survey results were subjected to statistical analyses. We also reviewed publicly available data regarding funding from the National Institutes of Health (NIH). Results NIH data revealed a 27% decline in the proportion of NIH funding to surgical departments relative to total NIH funding from 2007 to 2014. A total of 1033 (41%) members responded to our survey, making this the largest survey of academic surgeons to date. Surgeons most often cited the following factors as major impediments to pursuing basic investigation: pressure to be clinically productive, excessive administrative responsibilities, difficulty obtaining extramural funding, and desire for work-life balance. Surprisingly, a majority (68%) did not believe surgeons can be successful basic scientists in today’s environment, including departmental leadership. Conclusions We have identified important barriers that confront academic surgeons pursuing basic research and a perception that success in basic science may no longer be achievable. These barriers need to be addressed to ensure the continued development of future surgeon-scientists. PMID:27643928

  17. Particle behavior and char burnout mechanisms under pressurized combustion conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bauer, C.M.; Spliethoff, H.; Hein, K.R.G.

    Combined cycle systems with coal-fired gas turbines promise highest cycle efficiencies for this fuel. Pressurized pulverized coal combustion, in particular, yields high cycle efficiencies due to the high flue gas temperatures possible. The main problem, however, is to ensure a flue gas clean enough to meet the high gas turbine standards with a dirty fuel like coal. On the one hand, a profound knowledge of the basic chemical and physical processes during fuel conversion under elevated pressures is required whereas on the other hand suitable hot gas cleaning systems need to be developed. The objective of this work was tomore » provide experimental data to enable a detailed description of pressurized coal combustion processes. A series of experiments were performed with two German hvb coals, Ensdorf and Goettelborn, and one German brown coal, Garzweiler, using a semi-technical scale pressurized entrained flow reactor. The parameters varied in the experiments were pressure, gas temperature and bulk gas oxygen concentration. A two-color pyrometer was used for in-situ determination of particle surface temperatures and particle sizes. Flue gas composition was measured and solid residue samples taken and subsequently analyzed. The char burnout reaction rates were determinated varying the parameters pressure, gas temperature and initial oxygen concentration. Variation of residence time was achieved by taking the samples at different points along the reaction zone. The most influential parameters on char burnout reaction rates were found to be oxygen partial pressure and fuel volatile content. With increasing pressure the burn-out reactions are accelerated and are mostly controlled by product desorption and pore diffusion being the limiting processes. The char burnout process is enhanced by a higher fuel volatile content.« less

  18. Military Potential Test of Elapsed-Time Indicator, P/N 85986X

    DTIC Science & Technology

    1967-06-13

    consisting basically of an electrolytic mercury cell, an accutron-quality mercury battery, and a pressure switch . The unit weighs 1. 687 ounces. Installed, it...orientation from 18 inches’ distance. The test item is actuated by a pressure switch which senses an actuating pressure of 40 t 5 pounds per square inch

  19. Motion compensated image processing and optimal parameters for egg crack detection using modified pressure

    USDA-ARS?s Scientific Manuscript database

    Shell eggs with microcracks are often undetected during egg grading processes. In the past, a modified pressure imaging system was developed to detect eggs with microcracks without adversely affecting the quality of normal intact eggs. The basic idea of the modified pressure imaging system was to ap...

  20. Career Education and the Marshmallow Principle.

    ERIC Educational Resources Information Center

    Hoyt, Kenneth B.

    The "Marshmallow Principle" introduced in this paper is stated as follows: "External pressure exerted on an organization to change its basic structure will, for as long as that pressure is applied, cause the organization's structure to bend and assume a new shape. Once the pressure is removed, the organization will reassume its original shape.…

  1. Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats.

    PubMed

    Tunctan, Bahar; Korkmaz, Belma; Cuez, Tuba; Kemal Buharalioglu, C; Sahan-Firat, Seyhan; Falck, John; Malik, Kafait U

    2010-11-01

    Our previous studies with the use of non-selective cyclooxygenase (COX) inhibitor, indomethacin, demonstrated that prostanoids produced during endotoxaemia increase inducible nitric oxide synthase (iNOS) protein expression and nitric oxide synthesis, and decrease cyctochrome P450 (CYP) 4A1 protein expression and CYP 4A activity. The results suggest that dual inhibition of iNOS and COX by indomethacin restores blood pressure presumably due to increased production of 20-hydroxyeicosatetraenoic acid (20-HETE) derived from CYP 4A in endotoxaemic rats. The present study examined whether increased levels of vasoconstrictor eicosanoids, 20-HETE, prostaglandin F(2α) (PGF(2α) )and thromboxane A(2) (TxA(2) ), would contribute to the effect of selective COX-2 inhibition to prevent endotoxin (ET)-induced fall in blood pressure associated with an increase in the production of vasodilator prostanoids, prostaglandin I(2) (PGI(2) ) and prostaglandin E(2) (PGE(2) ) and nitric oxide synthesis. Mean arterial blood pressure fell by 31 mmHg and heart rate (HR) rose by 90 beats/min. in male Wistar rats treated with ET (10 mg/kg, i.p.). The fall in mean arterial pressure and increase in HR were associated with increased levels of 6-keto-prostaglandin F(1α) (6-keto-PGF(1α) ), PGE(2) , TxB(2) , and nitrite in the serum, kidney, heart, thoracic aorta and/or superior mesenteric artery. Systemic and renal 20-HETE and PGF(2α) levels were also decreased in endotoxaemic rats. These effects of ET were prevented by a selective COX-2 inhibitor, N-(2-cyclohexyloxy-4-nitrophenyl)methansulphonamide (10 mg/kg, i.p.), given 1 hr after injection of ET. These data suggest that an increase in 20-HETE and PGF(2α) levels associated with decreased production of PGI(2) , PGE(2) , and TxA(2) , and nitric oxide synthesis contributes to the effect of selective COX-2 inhibitor to prevent the hypotension during rat endotoxaemia. © 2010 The Authors. Basic & Clinical Pharmacology & Toxicology © 2010 Nordic Pharmacological Society.

  2. Fast analysis of doping agents in urine by ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry. II: Confirmatory analysis.

    PubMed

    Badoud, F; Grata, E; Perrenoud, L; Saugy, M; Rudaz, S; Veuthey, J-L

    2010-06-18

    For doping control, analyses of samples are generally achieved in two steps: a rapid screening and, in the case of a positive result, a confirmatory analysis. A two-step methodology based on ultra-high-pressure liquid chromatography coupled to a quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) was developed to screen and confirm 103 doping agents from various classes (e.g., beta-blockers, stimulants, diuretics, and narcotics). The screening method was presented in a previous article as part I (i.e., Fast analysis of doping agents in urine by ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry. Part I: screening analysis). For the confirmatory method, basic, neutral and acidic compounds were extracted by a dedicated solid-phase extraction (SPE) in a 96-well plate format and detected by MS in the tandem mode to obtain precursor and characteristic product ions. The mass accuracy and the elemental composition of precursor and product ions were used for compound identification. After validation including matrix effect determination, the method was considered reliable to confirm suspect results without ambiguity according to the positivity criteria established by the World Anti-Doping Agency (WADA). Moreover, an isocratic method was developed to separate ephedrine from its isomer pseudoephedrine and cathine from phenylpropanolamine in a single run, what allowed their direct quantification in urine. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  3. Traditional Chinese Medicine, Food Therapy, and Hypertension Control: A Narrative Review of Chinese Literature.

    PubMed

    Zou, Ping

    2016-01-01

    Despite the lack of English literature about Traditional Chinese Medicine (TCM) food therapy, there is abundant Chinese literature about the application of food therapy for hypertension control. This paper summarizes basic concepts of TCM, the principles of food therapy and its application for hypertension control according to Chinese literature. In TCM, food is conceptualized according to both nutritional and functional aspects, and can be used to treat illnesses. Four principles of TCM food therapy including light eating, balancing the "hot" and "cold" nature of food, the harmony of the five flavors of food, and consistency between dietary intake and different health conditions, can be used to facilitate hypertension control. Based on a statistical analysis of antihypertensive foods recommended in 20 books on the application of food therapy for hypertension control, the 38 most frequently recommended are celery, tomato, banana, hawthorn, garlic, onion, seaweed, apple, corn, green beans, persimmon, laver, kiwi, watermelon, eggplant, carrots, mushroom, peanut, soy products, sea cucumber, buckwheat, garland chrysanthemum, spinach, honey, dairy products, vinegar, black fungus, jellyfish, green onion, shepherd's purse, soybean, potato, pear, winter melon, bitter melon, oat, pea, and tea. Food therapy emphasizes the therapeutic effects of food, considering its nature, taste, and function on human balanced health, which leads to optimal blood pressure control. Current literature suggests that food therapy is effective in blood pressure control and can be incorporated into blood pressure self-management in the Chinese population.

  4. Productive and Participatory: Basic Education for High-Performing and Actively Engaged Workers

    ERIC Educational Resources Information Center

    Jurmo, Paul

    2010-01-01

    The adult basic education field in the United States has experienced an ebb and flow of interest and investment in "worker education" over the past three decades. Although the rhetoric around workplace basic skills tends to focus on such outcomes as productivity and competitiveness, some proponents of worker basic education see it as a…

  5. Recovery of Anthocyanins Using Membrane Technologies: A Review.

    PubMed

    Martín, Julia; Díaz-Montaña, Enrique Jacobo; Asuero, Agustin G

    2018-05-04

    Anthocyanins are naturally occurring polyphenolic compounds and give many flowers, fruits and vegetable their orange, red, purple and blue colors. Besides their color attributes, anthocyanins have received much attention in recent years due to the growing evidence of their antioxidant capacity and health benefits on humans. However, these compounds usually occur in low concentrations in mixtures of complex matrices, and therefore large-scale harvesting is needed to obtain sufficient amounts for their practical usage. Effective fractionation or separation technologies are therefore essential for the screening and production of these bioactive compounds. In this context, membrane technologies have become popular due to their operational simplicity, the capacity to achieve good simultaneous separation/pre-concentration and matrix reduction with lower temperature and lower operating cost in comparison to other sample preparation methods. Membrane fractionation is based on the molecular or particle sizes (pressure-driven processes), on their charge (electrically driven processes) or are dependent on both size and charge. Other non-pressure-driven membrane processes (osmotic pressure and vapor pressure-driven) have been developed in recent years and employed as alternatives for the separation or fractionation of bioactive compounds at ambient conditions without product deterioration. These technologies are applied either individually or in combination as an integrated membrane system to meet the different requirements for the separation of bioactive compounds. The first section of this review examines the basic principles of membrane processes, including the different types of membranes, their structure, morphology and geometry. The most frequently used techniques are also discussed. Last, the specific application of these technologies for the separation, purification and concentration of phenolic compounds, with special emphasis on anthocyanins, are also provided.

  6. Outcome analysis of hemoglobin A1c, weight, and blood pressure in a VA diabetes education program.

    PubMed

    North, Susan L; Palmer, Glen A

    2015-01-01

    To determine the effect of a specific diabetes education class (Basics) on hemoglobin A1c values, weight, and systolic blood pressure. In this retrospective study, the researchers compared 2 groups of male veterans with a recent diagnosis of type 2 diabetes. One group received diabetes group education (n = 175) over a 4-month period, and the other received standard diabetes management follow-up (n = 184). Outpatient clinic setting in the Midwest. Basics class compared with standard level of care. Pre- and post-laboratory values for hemoglobin A1c, weight, and systolic blood pressure. Multivariate analysis of covariance and follow-up univariate statistics for significant differences. Findings revealed significant differences in hemoglobin A1c (P < .001) and weight (P < .001) in the treatment group compared with the control group. No significant difference was found in systolic blood pressure readings between the 2 groups. There was a significant difference in weight change between groups, with the treatment group demonstrating greater weight loss. There was an association between participation in the Basics diabetes education curriculum and reduction of hemoglobin A1c values. Some participants also had added benefit of significant weight loss. Published by Elsevier Inc.

  7. Introversion associated with large differences between screening blood pressure and home blood pressure measurement: The Ohasama study.

    PubMed

    Hozawa, Atsushi; Ohkubo, Takayoshi; Obara, Taku; Metoki, Hirohito; Kikuya, Masahiro; Asayama, Kei; Totsune, Kazuhito; Hashimoto, Junichiro; Hoshi, Haruhisa; Arai, Yumiko; Satoh, Hiroshi; Hosokawa, Toru; Imai, Yutaka

    2006-11-01

    To explore the effect of personality on screening blood pressures measured in clinical settings and home blood pressure measurements. From 1997 to 1999, 699 participants underwent screening and home blood pressure measurements and completed the Japanese version of the short-form Eysenck personality questionnaire. An increased screening blood pressure was defined as screening blood pressure > or = 140/90 mmHg and an increased home blood pressure was defined as home blood pressure > or = 135/85 mmHg. Participants with lower extroversion scores (i.e., introversion) showed a greater difference between screening and home systolic blood pressure. The association between introversion and differences was statistically significant, even after adjustment for other possible factors (younger age, female, wide screening pulse pressure, never smoked, and no antihypertensive medication). The adjusted means of SBP differences were 7.3 and 4.4 mmHg among the lowest and highest extroversion quartiles, respectively (P for trend = 0.02). Other personality scores (psychoticism or neuroticism) were not associated with screening and home blood pressure differences. The incorporation of an extroversion score in the basic model consisting of the above factors that affected the difference between screening and home blood pressure slightly improved the prediction of a high home blood pressure. The area under the receiver operating characteristic curve increased by 0.037 among participants with high screening blood pressure and 0.006 for those with normal screening blood pressure compared with the basic model. Physicians may need to be aware of 'introverted' patients who have high blood pressure in clinic settings, because they have the potential for 'white-coat' hypertension.

  8. High Pressure Laminates with Antimicrobial Properties

    PubMed Central

    Magina, Sandra; Santos, Mauro D.; Ferra, João; Cruz, Paulo; Portugal, Inês; Evtuguin, Dmitry

    2016-01-01

    High-pressure laminates (HPLs) are durable, resistant to environmental effects and good cost-benefit decorative surface composite materials with special properties tailored to meet market demand. In the present work, polyhexamethylene biguanide (PHMB) was incorporated for the first time into melamine-formaldehyde resin (MF) matrix on the outer layer of HPLs to provide them antimicrobial properties. Chemical binding of PHMB to resin matrix was detected on the surface of produced HPLs by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Antimicrobial evaluation tests were carried out on the ensuing HPLs doped with PHMB against gram-positive Listeria innocua and gram-negative Escherichia coli bacteria. The results revealed that laminates prepared with 1.0 wt % PHMB in MF resin were bacteriostatic (i.e., inhibited the growth of microorganisms), whereas those prepared with 2.4 wt % PHMB in MF resin exhibited bactericidal activity (i.e., inactivated the inoculated microorganisms). The results herein reported disclose a promising strategy for the production of HPLs with antimicrobial activity without affecting basic intrinsic quality parameters of composite material. PMID:28787897

  9. High Pressure Laminates with Antimicrobial Properties.

    PubMed

    Magina, Sandra; Santos, Mauro D; Ferra, João; Cruz, Paulo; Portugal, Inês; Evtuguin, Dmitry

    2016-02-06

    High-pressure laminates (HPLs) are durable, resistant to environmental effects and good cost-benefit decorative surface composite materials with special properties tailored to meet market demand. In the present work, polyhexamethylene biguanide (PHMB) was incorporated for the first time into melamine-formaldehyde resin (MF) matrix on the outer layer of HPLs to provide them antimicrobial properties. Chemical binding of PHMB to resin matrix was detected on the surface of produced HPLs by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Antimicrobial evaluation tests were carried out on the ensuing HPLs doped with PHMB against gram-positive Listeria innocua and gram-negative Escherichia coli bacteria. The results revealed that laminates prepared with 1.0 wt % PHMB in MF resin were bacteriostatic ( i.e. , inhibited the growth of microorganisms), whereas those prepared with 2.4 wt % PHMB in MF resin exhibited bactericidal activity ( i.e. , inactivated the inoculated microorganisms). The results herein reported disclose a promising strategy for the production of HPLs with antimicrobial activity without affecting basic intrinsic quality parameters of composite material.

  10. Numerical Investigation of Flow in a Centrifugal Compressor

    NASA Astrophysics Data System (ADS)

    Grishin, Yu. A.; Bakulin, V. N.

    2015-09-01

    With the use of the domestic software suite of computational hydrodynamics Flow Vision based on application of the method of control volumes, numerical simulation of air composition and delivery by a centrifugal compressor employed for supercharging a piston engine has been carried out. The head-flow characteristics of the compressor, as well as the 3D fields of flow velocity and pressure distributions in the elements of the compressor flow passage, including the interblade channels of the impeller, have been obtained for various regimes. In the regimes of diminished air flow rate, surging phenomena are identified, characterized by a return flow. The application of the technique of numerical experiment will make it possible from here on to carry out design optimization of the compressor flow passage profile and thus to improve its basic characteristics — the degree of pressure increase, compressed air flow rate, and the efficiency — as well as to reduce the costs of the development and production of compressors.

  11. Formation of ammonia from dinitrogen under primordial conditions

    NASA Astrophysics Data System (ADS)

    Weigand, W.; Dörr, M.; Robl, C.; Kreisel, G.; Grunert, R.; Käßbohrer, J.; Brand, W.; Werner, R.; Popp, J.; Tarcea, N.

    2002-11-01

    Ammonia is one of the most largely industrially produced basic compounds, leading to a variety of important secondary products. In the chemical industry, ammonia is produced in large amounts via the HABER-BOSCH-process. In contrast to the industrial process, the nitrogenase enzyme operates in organisms under very mild conditions at atmospheric pressure and ambient temperature. In this article, we describe a method for the synthesis of ammonia from molecular nitrogen using H2S and freshly precipitated iron sulfide as a mediator thus serving as a primordial inorganic substitute for the enzyme nitrogenase. The reductand, as well as the reaction conditions (atmospheric nitrogen pressure and temperatures on the order of 70 - 80°C) are rather mild and therefore comparable to the biological processes. The driving force of the overall reaction is believed to be the oxidation of iron sulfide to iron disulfide, and the formation of hydrogen from H2S. The reactions reported in this article may support the theory of an archaic nitrogen-fixing Fe-S cluster.

  12. Optimizing parameters of GTU cycle and design values of air-gas channel in a gas turbine with cooled nozzle and rotor blades

    NASA Astrophysics Data System (ADS)

    Kler, A. M.; Zakharov, Yu. B.

    2012-09-01

    The authors have formulated the problem of joint optimization of pressure and temperature of combustion products before gas turbine, profiles of nozzle and rotor blades of gas turbine, and cooling air flow rates through nozzle and rotor blades. The article offers an original approach to optimization of profiles of gas turbine blades where the optimized profiles are presented as linear combinations of preliminarily formed basic profiles. The given examples relate to optimization of the gas turbine unit on the criterion of power efficiency at preliminary heat removal from air flows supplied for the air-gas channel cooling and without such removal.

  13. Design considerations in mechanical face seals for improved performance. 1: Basic configurations

    NASA Technical Reports Server (NTRS)

    Ludwig, L. P.; Greiner, H. F.

    1977-01-01

    Basic assembly configurations of the mechanical face seal are described and some advantages associated with each are listed. The various forms of seal components are illustrated, and functions pointed out. The technique of seal pressure balancing and its application are described; and the concept of the PV factor, its different forms and limitations are discussed. Brief attention is given to seal lubrication since it is covered in detail in a companion paper. Finally, the operating conditions for various applications of low pressure seals (aircraft transmissions) are listed, and the seal failure mode of a particular application is discussed.

  14. Low Pressure Spark Gap

    DTIC Science & Technology

    1981-06-01

    voltage electrode and forms the interface between the water and vacuum. Figure 1 Low Pressure Switch Apparatus 380 The water Blumlein, the...buildup of current and can predict the rate constant within 30%, it appears that we understand the basic mechanism of the low pressure switch . 0.22...E. J. Lauer, "Status of Low Pressure Switch Research and Development," UCID 17998, Dec. 12, 1978. 4. E. J. Lauer, S. S. Yu and D. M. Cox, "Onset

  15. Basic Pressure Measurements at Transonic Speeds on a Thin 45 deg Sweptback Highly Tapered Wing with Systematic Spanwise Twist Variations

    NASA Technical Reports Server (NTRS)

    Mugler, John P., Jr.

    1958-01-01

    Pressure distributions are presented for a thin highly tapered untwisted 45 deg sweptback wing in combination with a body. These tests were made in the Langley 8-foot transonic pressure tunnel at both 1.0 and 0.5 atmosphere stagnation pressures at Mach numbers from 0.800 to 1.200 through an angle-of-attack range of -4 deg to 12 deg.

  16. [Support devices for the prevention and treatment of pressure sores].

    PubMed

    Perrouin-Verbe, Brigite

    2014-12-01

    There is a strategy to be followed in the treatment of patients with specific pathologies placing them at high risk of pressure sores. In some cases, sophisticated support devices are used.These techniques must be combined with basic good practices.

  17. A method for estimating fall adult sex ratios from production and survival data

    USGS Publications Warehouse

    Wight, H.M.; Heath, R.G.; Geis, A.D.

    1965-01-01

    This paper presents a method of utilizing data relating to the production and survival of a bird population to estimate a basic fall adult sex ratio. This basic adult sex ratio is an average value derived from average production and survival rates. It is an estimate of the average sex ratio about which the fall adult ratios will fluctuate according to annual variations in production and survival. The basic fall adult sex ratio has been calculated as an asymptotic value which is the limit of an infinite series wherein average population characteristics are used as constants. Graphs are provided that allow the determination of basic sex ratios from production and survival data of a population. Where the respective asymptote has been determined, it may be possible to estimate various production and survival rates by use of variations of the formula for estimating the asymptote.

  18. Ultra-high pressure water jetting for coating removal and surface preparation

    NASA Technical Reports Server (NTRS)

    Johnson, Spencer T.

    1995-01-01

    This paper shall examine the basics of water technology with particular attention paid to systems currently in use and some select new applications. By providing an overview of commercially available water jet systems in the context of recent case histories, potential users may evaluate the process for future applications. With the on going introduction of regulations prohibiting the use of chemical paint strippers, manual scrapping and dry abrasive media blasting, the need for an environmentally compliant coating removal process has been mandated. Water jet cleaning has been a traditional part of many industrial processed for year, although it has only been in the last few years that reliable pumping equipment capable of ultra-high pressure operation have become available. With the advent of water jet pumping equipment capable of sustaining pressures in excess of 36,000 psi. there has been shift away from lower pressure, high water volume systems. One of the major factors in driving industry to seek higher pressures is the ability to offer higher productivity rates while lowering the quantity of water used and subsequently reprocessed. Among benefits of the trend toward higher pressure/lower volume systems is the corresponding reduction in water jet reaction forces making hand held water jetting practical and safe. Other unique applications made possible by these new generation pumping systems include the use of alternative fluids including liquid ammonia for specialized and hazardous material removal applications. A review of the equipment used and the required modifications will be presented along with the conclusions reached reached during this test program.

  19. 16 CFR Figure 2 to Part 1203 - ISO Headform-Basic, Reference, and Median Planes

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false ISO Headform-Basic, Reference, and Median Planes 2 Figure 2 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT... Headform-Basic, Reference, and Median Planes ER10MR98.002 ...

  20. Arterial Pressure Analog.

    ERIC Educational Resources Information Center

    Heusner, A. A.; Tracy, M. L.

    1980-01-01

    Describes a simple hydraulic analog which allows students to explore some physical aspects of the cardiovascular system and provides them with a means to visualize and conceptualize these basic principles. Simulates the behavior of arterial pressure in response to changes in heart rate, stroke volume, arterial compliance, and peripheral…

  1. Grain-size-independent plastic flow at ultrahigh pressures and strain rates.

    PubMed

    Park, H-S; Rudd, R E; Cavallo, R M; Barton, N R; Arsenlis, A; Belof, J L; Blobaum, K J M; El-dasher, B S; Florando, J N; Huntington, C M; Maddox, B R; May, M J; Plechaty, C; Prisbrey, S T; Remington, B A; Wallace, R J; Wehrenberg, C E; Wilson, M J; Comley, A J; Giraldez, E; Nikroo, A; Farrell, M; Randall, G; Gray, G T

    2015-02-13

    A basic tenet of material science is that the flow stress of a metal increases as its grain size decreases, an effect described by the Hall-Petch relation. This relation is used extensively in material design to optimize the hardness, durability, survivability, and ductility of structural metals. This Letter reports experimental results in a new regime of high pressures and strain rates that challenge this basic tenet of mechanical metallurgy. We report measurements of the plastic flow of the model body-centered-cubic metal tantalum made under conditions of high pressure (>100  GPa) and strain rate (∼10(7)  s(-1)) achieved by using the Omega laser. Under these unique plastic deformation ("flow") conditions, the effect of grain size is found to be negligible for grain sizes >0.25  μm sizes. A multiscale model of the plastic flow suggests that pressure and strain rate hardening dominate over the grain-size effects. Theoretical estimates, based on grain compatibility and geometrically necessary dislocations, corroborate this conclusion.

  2. Cardio-ankle vascular index (CAVI) differentiates pharmacological properties of vasodilators nicardipine and nitroglycerin in anesthetized rabbits.

    PubMed

    Chiba, Tatsuo; Yamanaka, Mari; Takagi, Sachie; Shimizu, Kazuhiro; Takahashi, Mao; Shirai, Kohji; Takahara, Akira

    2015-08-01

    Cardio-ankle vascular index (CAVI) has been developed for measurement of vascular stiffness from the aorta to tibial artery, which is clinically utilized for assessing the progress of arteriosclerosis. In this study, we established measuring system of the CAVI in rabbits, and assessed whether the index could reflect different pharmacological actions of nitroglycerin and nicardipine on the systemic vasculature. Rabbits were anesthetized with halothane, and the CAVI was calculated from the well-established basic equations with variables obtained from brachial and tibial blood pressure and phonocardiogram. Nicardipine (1, 3 and 10 μg/kg, i.v.) decreased the blood pressure, femoral vascular resistance, and heart-ankle pulse wave velocity (haPWV). Meanwhile, no significant change was detected in the CAVI at the low or middle dose, which reflects the defining feature of the CAVI that is independent of blood pressure. The index increased at the high dose. Nitroglycerin (2, 4 and 8 μg/kg, i.v.) decreased the blood pressure, femoral vascular resistance, and haPWV. Meanwhile, the CAVI was decreased during the nitroglycerin infusion, which may reflect its well-known pharmacological action dilating conduit arteries. These results suggest that the CAVI differentiates the properties of these vasodilators in vivo. Copyright © 2015 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

  3. Pressure-induced orientational glass phase in molecular para-hydrogen.

    PubMed

    Schelkacheva, T I; Tareyeva, E E; Chtchelkatchev, N M

    2009-02-01

    We propose a theoretical description of a possible orientational glass transition in solid molecular para-hydrogen and ortho-deuterium under pressure supposing that they are mixtures of J=0 and J=2 states of molecules. The theory uses the basic concepts and methods of standard spin-glass theory. We expect our orientational glass to correspond to the II' phase of the high-pressure hydrogen phase diagram.

  4. PRESSURE TRANSDUCER

    DOEpatents

    Sander, H.H.

    1959-10-01

    A pressure or mechanical force transducer particularly adaptable to miniature telemetering systems is described. Basically the device consists of a transistor located within a magnetic field adapted to change in response to mechanical force. The conduction characteristics of the transistor in turn vary proportionally with changes in the magnetic flux across the transistor such that the output (either frequency of amplitude) of the transistor circuit is proportional to mechanical force or pressure.

  5. Implementation of a low-cost, commercial orbit determination system

    NASA Technical Reports Server (NTRS)

    Corrigan, Jim

    1994-01-01

    This paper describes the implementation and potential applications of a workstation-based orbit determination system developed by Storm Integration, Inc. called the Precision Orbit Determination System (PODS). PODS is offered as a layered product to the commercially-available Satellite Tool Kit (STK) produced by Analytical Graphics, Inc. PODS also incorporates the Workstation/Precision Orbit Determination (WS/POD) product offered by Van Martin System, Inc. The STK graphical user interface is used to access and invoke the PODS capabilities and to display the results. WS/POD is used to compute a best-fit solution to user-supplied tracking data. PODS provides the capability to simultaneously estimate the orbits of up to 99 satellites based on a wide variety of observation types including angles, range, range rate, and Global Positioning System (GPS) data. PODS can also estimate ground facility locations, Earth geopotential model coefficients, solar pressure and atmospheric drag parameters, and observation data biases. All determined data is automatically incorporated into the STK data base, which allows storage, manipulation and export of the data to other applications. PODS is offered in three levels: Standard, Basic GPS and Extended GPS. Standard allows processing of non-GPS observation types for any number of vehicles and facilities. Basic GPS adds processing of GPS pseudo-ranging data to the Standard capabilities. Extended GPS adds the ability to process GPS carrier phase data.

  6. Integration of Basic Knowledge Models for the Simulation of Cereal Foods Processing and Properties.

    PubMed

    Kristiawan, Magdalena; Kansou, Kamal; Valle, Guy Della

    Cereal processing (breadmaking, extrusion, pasting, etc.) covers a range of mechanisms that, despite their diversity, can be often reduced to a succession of two core phenomena: (1) the transition from a divided solid medium (the flour) to a continuous one through hydration, mechanical, biochemical, and thermal actions and (2) the expansion of a continuous matrix toward a porous structure as a result of the growth of bubble nuclei either by yeast fermentation or by water vaporization after a sudden pressure drop. Modeling them is critical for the domain, but can be quite challenging to address with mechanistic approaches relying on partial differential equations. In this chapter we present alternative approaches through basic knowledge models (BKM) that integrate scientific and expert knowledge, and possess operational interest for domain specialists. Using these BKMs, simulations of two cereal foods processes, extrusion and breadmaking, are provided by focusing on the two core phenomena. To support the use by non-specialists, these BKMs are implemented as computer tools, a Knowledge-Based System developed for the modeling of the flour mixing operation or Ludovic ® , a simulation software for twin screw extrusion. They can be applied to a wide domain of compositions, provided that the data on product rheological properties are available. Finally, it is stated that the use of such systems can help food engineers to design cereal food products and predict their texture properties.

  7. Beyond the basics: brain injuries.

    PubMed

    Duncan, Tim; Krost, William S; Mistovich, Joseph J; Limmer, Daniel

    2007-07-01

    Increased intracranial pressure can be a catastrophic event that may lead to death or permanent disability. Without prompt recognition and reversal of hypoxia, hypotension, hypercarbia, acidosis and increased intracranial pressure, the cerebral blood flow and resultant cerebral perfusion can be inadequate, leading to an exacerbation of secondary brain injury.

  8. Basic Workplace Skills: The Foundation for Productivity Improvement. Workforce Brief #4.

    ERIC Educational Resources Information Center

    Bergman, Terri

    Studies have confirmed that there is a strong correlation between employees' levels of basic workplace skills and their productivity in the workplace. Programs to build basic workplace skills have been shown to yield the following positive results: more instances of employees using reading and writing on the job, higher employee participation in…

  9. Differential Roles for the Thyroarytenoid and Lateral Cricoarytenoid Muscles in Phonation

    PubMed Central

    Chhetri, Dinesh K.; Neubauer, Juergen

    2015-01-01

    Objective Laryngeal adductor muscle dysfunction is common cause of voice disorders. Reconstitution of adductor muscle function is often the target of therapy, but the effects of these muscles on voice production remain to be fully understood. This study investigated the differential roles of thyroarytenoid (TA) and lateral cricoarytenoid (LCA) muscles on voice production. Study Design Basic science study using an in vivo canine model of phonation. Methods The TA and LCA muscle nerve branches were stimulated to obtain 7 graded levels of muscle activation, from threshold to maximal contraction. The effects of LCA activation alone, TA activation alone, and combined TA and LCA activation on phonation onset parameters were investigated. Phonatory posture, phonation onset type, fundamental frequency (F0), phonation onset pressure, and airflow were evaluated. Results LCA activation closed the posterior glottis but mid-membranous gap remained. TA activation closed the membranous glottis but posterior gap remained. Complete glottal closure was obtained only with combined TA and LCA activation. Phonation onset with LCAs alone was characterized by multiple modes (soft, aperiodic, periodic), while with TAs alone was abrupt and periodic but had significant baseline noise. Combined muscle activation led to elimination of baseline noise with stable abrupt periodic onset of phonation. Combined muscle activation was also necessary for F0 variation. LCA assisted the TA in increasing subglottal pressure while concurrently reducing phonation onset airflow. Conclusion TA is necessary for F0 variation, stable onset phonation, and increased subglottal pressure but needs LCA for optimal effectiveness and to reduce airflow requirements with increased activation. PMID:26198167

  10. Re-Modeling Basic Writing

    ERIC Educational Resources Information Center

    Rigolino, Rachel; Freel, Penny

    2007-01-01

    In 1996, the State University of New York at New Paltz developed the Supplemental Writing Workshop Program for its basic writing students in response to public pressure to discontinue the offering of so-called remedial writing courses at four-year institutions. Our primary purpose in this article is to describe the design of the SWW Program, which…

  11. Mississippi's forest products industry: performance and contribution to the State's economy, 1970 to 1980.

    Treesearch

    Con H Schallau; Wilbur R. Maki; Bennett B. Foster; Clair H. Redmond

    1988-01-01

    The forest products industry is one of Mississippi's basic industries, and in 1980, it accounted for about one of six basic jobs. Mississippi was one of the majority of Southern States in which the forest products industry improved its competitive position during the 1970's. Between 1972 and 1977, growth in productivity of Mississippi's forest products...

  12. Control of the dehydration process in production of intermediate-moisture meat products: a review.

    PubMed

    Chang, S F; Huang, T C; Pearson, A M

    1996-01-01

    IM meat products are produced by lowering the aw to 0.90 to 0.60. Such products are stable at ambient temperature and humidity and are produced in nearly every country in the world, especially in developing areas where refrigeration is limited or unavailable. Traditionally IM meats use low cost sources of energy for drying, such as sun drying, addition of salt, or fermentation. Products produced by different processes are of interest since they do not require refrigeration during distribution and storage. Many different IM meat products can be produced by utilizing modern processing equipment and methods. Production can be achieved in a relatively short period of time and their advantages during marketing and distribution can be utilized. Nevertheless, a better understanding of the principles involved in heat transfer and efficiency of production are still needed to increase efficiency of processing. A basic understanding of the influence of water vapor pressure and sorption phenomena on water activity can materially improve the efficiency of drying of IM meats. Predrying treatments, such as fermentation and humidity control, can also be taken advantage of during the dehydration process. Such information can lead to process optimization and reduction of energy costs during production of IM meats. The development of sound science-based methods to assure the production of high-quality and nutritious IM meats is needed. Finally, such products also must be free of pathogenic microorganisms to assure their success in production and marketing.

  13. Oxygen Transport: A Simple Model for Study and Examination.

    ERIC Educational Resources Information Center

    Gaar, Kermit A., Jr.

    1985-01-01

    Describes an oxygen transport model computer program (written in Applesoft BASIC) which uses such variables as amount of time lapse from beginning of the simulation, arterial blood oxygen concentration, alveolar oxygen pressure, and venous blood oxygen concentration and pressure. Includes information on obtaining the program and its documentation.…

  14. A system for the automatic measurement and digital display of systolic and diastolic blood pressures

    NASA Technical Reports Server (NTRS)

    Schulze, A. E.

    1971-01-01

    Basic components of system are - occluding cuff with mounted cuff microscope, cuff pump deflator, pressure transducer, preamplifier unit, electrocardiograph machine, an analog to digital convertor unit, and digital display unit. System utilizes indirect auscultatory method, based on Korotkoff sounds, for measurement.

  15. CBM Resources/reserves classification and evaluation based on PRMS rules

    NASA Astrophysics Data System (ADS)

    Fa, Guifang; Yuan, Ruie; Wang, Zuoqian; Lan, Jun; Zhao, Jian; Xia, Mingjun; Cai, Dechao; Yi, Yanjing

    2018-02-01

    This paper introduces a set of definitions and classification requirements for coalbed methane (CBM) resources/reserves, based on Petroleum Resources Management System (PRMS). The basic CBM classification criterions of 1P, 2P, 3P and contingent resources are put forward from the following aspects: ownership, project maturity, drilling requirements, testing requirements, economic requirements, infrastructure and market, timing of production and development, and so on. The volumetric method is used to evaluate the OGIP, with focuses on analyses of key parameters and principles of the parameter selection, such as net thickness, ash and water content, coal rank and composition, coal density, cleat volume and saturation and absorbed gas content etc. A dynamic method is used to assess the reserves and recovery efficiency. Since the differences in rock and fluid properties, displacement mechanism, completion and operating practices and wellbore type resulted in different production curve characteristics, the factors affecting production behavior, the dewatering period, pressure build-up and interference effects were analyzed. The conclusion and results that the paper achieved can be used as important references for reasonable assessment of CBM resources/reserves.

  16. Direct Measurement of Intracellular Pressure

    PubMed Central

    Petrie, Ryan J.; Koo, Hyun

    2014-01-01

    A method to directly measure the intracellular pressure of adherent, migrating cells is described in the Basic Protocol. This approach is based on the servo-null method where a microelectrode is introduced into the cell to directly measure the physical pressure of the cytoplasm. We also describe the initial calibration of the microelectrode as well as the application of the method to cells migrating inside three-dimensional (3D) extracellular matrix (ECM). PMID:24894836

  17. Response of space shuttle insulation panels to acoustic noise pressure

    NASA Technical Reports Server (NTRS)

    Vaicaitis, R.

    1976-01-01

    The response of reusable space shuttle insulation panels to random acoustic pressure fields are studied. The basic analytical approach in formulating the governing equations of motion uses a Rayleigh-Ritz technique. The input pressure field is modeled as a stationary Gaussian random process for which the cross-spectral density function is known empirically from experimental measurements. The response calculations are performed in both frequency and time domain.

  18. Air Bag Applies Uniform Bonding Pressure

    NASA Technical Reports Server (NTRS)

    Gillespie, C. A.

    1982-01-01

    Air-bag box applies constant uniform pressure to tiles and other objects undergoing adhesive bonding. Box is basically a compliant clamp with adjustable force and position. Can be used on irregular surfaces as well as on flat ones. Pressurized air is fed to bag through a tube so that it expands, filling the box and pressing against work. Bag adopts a contour that accommodates surface under open side of box.

  19. KC-135 wing and winglet flight pressure distributions, loads, and wing deflection results with some wind tunnel comparisons

    NASA Technical Reports Server (NTRS)

    Montoya, L. C.; Jacobs, P.; Flechner, S.; Sims, R.

    1982-01-01

    A full-scale winglet flight test on a KC-135 airplane with an upper winglet was conducted. Data were taken at Mach numbers from 0.70 to 0.82 at altitudes from 34,000 feet to 39,000 feet at stabilized flight conditions for wing/winglet configurations of basic wing tip, 15/-4 deg, 15/-2 deg, and 0/-4 deg winglet cant/incidence. An analysis of selected pressure distribution and data showed that with the basic wing tip, the flight and wind tunnel wing pressure distribution data showed good agreement. With winglets installed, the effects on the wing pressure distribution were mainly near the tip. Also, the flight and wind tunnel winglet pressure distributions had some significant differences primarily due to the oilcanning in flight. However, in general, the agreement was good. For the winglet cant and incidence configuration presented, the incidence had the largest effect on the winglet pressure distributions. The incremental flight wing deflection data showed that the semispan wind tunnel model did a reasonable job of simulating the aeroelastic effects at the wing tip. The flight loads data showed good agreement with predictions at the design point and also substantiated the predicted structural penalty (load increase) of the 15 deg cant/-2 deg incidence winglet configuration.

  20. 16 CFR 305.8 - Submission of data.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... input voltage and frequency; (vi) Ballast efficacy factor; and (vii) Type (F40T12, F96T12 or F96T12HO..., heat pumps, furnaces, ceiling fans, and pool heaters) for each basic model in current production..., for each basic model in current production: the brand name; the model numbers for each basic model...

  1. 27 CFR 1.35 - Authority to issue, amend, deny, suspend, revoke, or annul basic permits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Authority to issue, amend, deny, suspend, revoke, or annul basic permits. 1.35 Section 1.35 Alcohol, Tobacco Products and Firearms... SALES AND BOTTLING OF DISTILLED SPIRITS Basic Permits Authorization § 1.35 Authority to issue, amend...

  2. Tennessee's forest products industry: performance and contribution to the State's economy, 1970 to 1980.

    Treesearch

    Wilbur R. Maki; Con H Schallau; Bennett B. Foster; Clair H. Redmond

    1987-01-01

    The forest products industry is one of Tennessee's basic industries; in 1980, for example, it accounted for about 1 of every 12 basic jobs. Furthermore, Tennessee was one of the majority of Southern States in which the forest products industry improved its competitive position during the 1970's. In 1977, productivity growth of the paper and allied products...

  3. In situ measurement of magnesium carbonate formation from CO2 using static high-pressure and -temperature 13C NMR.

    PubMed

    Surface, J Andrew; Skemer, Philip; Hayes, Sophia E; Conradi, Mark S

    2013-01-02

    We explore a new in situ NMR spectroscopy method that possesses the ability to monitor the chemical evolution of supercritical CO(2) in relevant conditions for geological CO(2) sequestration. As a model, we use the fast reaction of the mineral brucite, Mg(OH)(2), with supercritical CO(2) (88 bar) in aqueous conditions at 80 °C. The in situ conversion of CO(2) into metastable and stable carbonates is observed throughout the reaction. After more than 58 h of reaction, the sample was depressurized and analyzed using in situ Raman spectroscopy, where the laser was focused on the undisturbed products through the glass reaction tube. Postreaction, ex situ analysis was performed on the extracted and dried products using Raman spectroscopy, powder X-ray diffraction, and magic-angle spinning (1)H-decoupled (13)C NMR. These separate methods of analysis confirmed a spatial dependence of products, possibly caused by a gradient of reactant availability, pH, and/or a reaction mechanism that involves first forming hydroxy-hydrated (basic, hydrated) carbonates that convert to the end-product, anhydrous magnesite. This carbonation reaction illustrates the importance of static (unmixed) reaction systems at sequestration-like conditions.

  4. Aerobic Oxidation of Xylose to Xylaric acid in Water over Pt Catalysts.

    PubMed

    Saha, Basudeb; Sadula, Sunitha

    2018-05-02

    Energy-efficient catalytic conversion of biomass intermediates to functional chemicals can enable bio-products viable. Herein, we report an efficient and low temperature aerobic oxidation of xylose to xylaric acid, a promising bio-based chemical for the production of glutaric acid, over commercial catalysts in water. Among several heterogeneous catalysts investigated, Pt/C exhibits the best activity. Systematic variation of reaction parameters in the pH range of 2.5 to 10 suggests that the reaction is fast at higher temperatures but high C-C scission of intermediate C5-oxidized products to low carbon carboxylic acids undermines xylaric acid selectivity. The C-C cleavage is also high in basic solution. The oxidation at neutral pH and 60 C achieves the highest xylaric acid yield (64%). O2 pressure and Pt-amount have significant influence on the reactivity. Decarboxylation of short chain carboxylic acids results in formation of CO2, causing some carbon loss; however such decarboxylation is slow in the presence of xylose. The catalyst retained comparable activity, in terms of product selectivity, after five cycles with no sign of Pt leaching. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Sustainable food security in India-Domestic production and macronutrient availability.

    PubMed

    Ritchie, Hannah; Reay, David; Higgins, Peter

    2018-01-01

    India has been perceived as a development enigma: Recent rates of economic growth have not been matched by similar rates in health and nutritional improvements. To meet the second Sustainable Development Goal (SDG2) of achieving zero hunger by 2030, India faces a substantial challenge in meeting basic nutritional needs in addition to addressing population, environmental and dietary pressures. Here we have mapped-for the first time-the Indian food system from crop production to household-level availability across three key macronutrients categories of 'calories', 'digestible protein' and 'fat'. To better understand the potential of reduced food chain losses and improved crop yields to close future food deficits, scenario analysis was conducted to 2030 and 2050. Under India's current self-sufficiency model, our analysis indicates severe shortfalls in availability of all macronutrients across a large proportion (>60%) of the Indian population. The extent of projected shortfalls continues to grow such that, even in ambitious waste reduction and yield scenarios, enhanced domestic production alone will be inadequate in closing the nutrition supply gap. We suggest that to meet SDG2 India will need to take a combined approach of optimising domestic production and increasing its participation in global trade.

  6. Sustainable food security in India—Domestic production and macronutrient availability

    PubMed Central

    2018-01-01

    India has been perceived as a development enigma: Recent rates of economic growth have not been matched by similar rates in health and nutritional improvements. To meet the second Sustainable Development Goal (SDG2) of achieving zero hunger by 2030, India faces a substantial challenge in meeting basic nutritional needs in addition to addressing population, environmental and dietary pressures. Here we have mapped—for the first time—the Indian food system from crop production to household-level availability across three key macronutrients categories of ‘calories’, ‘digestible protein’ and ‘fat’. To better understand the potential of reduced food chain losses and improved crop yields to close future food deficits, scenario analysis was conducted to 2030 and 2050. Under India’s current self-sufficiency model, our analysis indicates severe shortfalls in availability of all macronutrients across a large proportion (>60%) of the Indian population. The extent of projected shortfalls continues to grow such that, even in ambitious waste reduction and yield scenarios, enhanced domestic production alone will be inadequate in closing the nutrition supply gap. We suggest that to meet SDG2 India will need to take a combined approach of optimising domestic production and increasing its participation in global trade. PMID:29570702

  7. Investigation of Pressurized Wave Bearings

    NASA Technical Reports Server (NTRS)

    Keith, Theo G., Jr.; Dimofte, Florin

    2003-01-01

    The wave bearing has been pioneered and developed by Dr. Dimofte over the past several years. This bearing will be the main focus of this research. It is believed that the wave bearing offers a number of advantages over the foil bearing, which is the bearing that NASA is currently pursuing for turbomachinery applications. The wave bearing is basically a journal bearing whose film thickness varies around the circumference approximately sinusoidally, with usually 3 or 4 waves. Being a rigid geometry bearing, it provides precise control of shaft centerlines. The wave profile also provides good load capacity and makes the bearing very stable. Manufacturing techniques have been devised that should allow the production of wave bearings almost as cheaply as conventional full-circular bearings.

  8. Dynamics of Geometrically Nonlinear Elastic Nonthin Anisotropic Shells of Variable Thickness

    NASA Astrophysics Data System (ADS)

    Marchuk, M. V.; Tuchapskii, R. I.

    2017-11-01

    A theory of dynamic elastic geometrically nonlinear deformation of nonthin anisotropic shells with variable thickness is constructed. Shells are assumed asymmetric about the reference surface. Functions are expanded into Legendre series. The basic equations are written in a coordinate system aligned with the lines of curvature of the reference surface. The equations of motion and appropriate boundary conditions are obtained using the Hamilton-Ostrogradsky variational principle. The change in metric across the thickness is taken into account. The theory assumes that the refinement process is regular and allows deriving equations including products of terms of Legendre series of unknown functions of arbitrary order. The behavior of a square metallic plate acted upon by a pressure pulse distributed over its face is studied.

  9. Gas pipeline relief valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bright, G.F.

    1974-01-01

    A discussion of the increasing activity of natural gas pipeline companies in the analysis of the overpressure protection methods for complying with the provisions of Part 192, Title 49, Code of Federal Regulations ''Transportation of Natural and Other Gas by Pipelines; Minimum Federal Safety Standards'' and with the USAS B31.8 Code covers the basic requirements for protection against accidental overpressure as being essentially the same in both documents, i.e., at the maximum allowable operating overpressure in a gas system can be exceeded either at a compressor station or downstream of a pressure control valve; mandatory use of overpressure protection devicesmore » in these situations, except for those cases which exempt some service regulators because the distribution system pressure is less than 60 psig and six other requirements of design, performance, and size are met; and basic design requirements of a pressure relief or limiting station and the components used.« less

  10. Protecting the Purity of Pure Research: Organizational Boundary-Work at an Institute of Basic Research

    ERIC Educational Resources Information Center

    Sapir, Adi

    2017-01-01

    Research institutions and universities are positioned in a state of inherent struggle to reconcile the pressures and demands of the external environment with those of the scientific community. This paper is focused on one contested area, the division between basic and applied research, and explores how universities work to balance organizational…

  11. [Possibilities of bi-level positive pressure ventilation in chronic hypoventilation].

    PubMed

    Saaresranta, Tarja; Anttalainen, Ulla; Polo, Olli

    2011-01-01

    During the last decade, noninvasive bi-level positive pressure ventilation has enabled respiratory support in inpatient wards and at home. In many cases, a bi-level airway pressure ventilator can be used to avoid artificial airway and respirator therapy, and may shorten hospital stay and save costs. The treatment alleviates the patient's dyspnea and fatigue, whereby the quality of life improves, and in certain situations also the life span increases. The implementation of bi-level positive pressure ventilation by the physician requires knowledge of the basics of respiratory physiology and familiarization with the bi-level airway pressure ventilator.

  12. Equine Management and Production. Vocational Agriculture Education.

    ERIC Educational Resources Information Center

    Rudolph, James A.

    This basic core of instruction for equine management and production is designed to assist instructors in preparing students for successful employment or management of a one- or two-horse operation. Contents include seven instructional areas totaling seventeen units of instruction: (1) Orientation (basic horse production; handling and grooming;…

  13. 77 FR 74616 - Amendments and Correction to Petitions for Waiver and Interim Waiver for Consumer Products and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... decision and order must be used for all future testing for any basic models covered by the decision and... require petitioners to: (1) Specify the basic model(s) to which the waiver applies; (2) identify other manufacturers of similar products; (3) include any known alternate test procedures of the basic model, with the...

  14. High pressure in bioscience and biotechnology: pure science encompassed in pursuit of value.

    PubMed

    Hayashi, Rikimaru

    2002-03-25

    A fundamental factors, pressure (P), is indispensable to develop and support applications in the field of bioscience and biotechnology. This short sentence describes an example how high pressure bioscience and biotechnology, which started from applied science, stimulates challenges of basic science and pure science in the biology-related fields including not only food science, medicine, and pharmacology but also biochemistry, molecular biology, cell biology, physical chemistry, and engineering.

  15. Pressure and Temperature Sensitive Paint Measurements on Rotors

    NASA Technical Reports Server (NTRS)

    Sullivan, John

    1999-01-01

    Luminescent molecular probes imbedded in a polymer binder form a temperature or pressure paint. On excitation by light of the proper wavelength, the luminescence, which is quenched either thermally or by oxygen, is detected by a camera or photodetector. From the detected luminescent intensity, temperature and pressure can be determined. The basic photophysics, calibration, accuracy and time response of luminescent paints is described followed by applications in wind tunnels and in rotating machinery.

  16. 30 CFR 250.527 - What must I include in my casing pressure request?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... casing/riser calculated MAWOPs; (h) All casing/riser pre-bleed down pressures; (i) Shut-in tubing... test (oil, gas, basic sediment, and water); (l) Well status (shut-in, temporarily abandoned, producing, injecting, or gas lift); (m) Well type (dry tree, hybrid, or subsea); (n) Date of diagnostic test; (o) Well...

  17. Electrical conductivity of MgH2 at multiple shock compression

    NASA Astrophysics Data System (ADS)

    Shakhray, Denis; Molodets, Alexander; Fortov, Vladimir

    2011-06-01

    The electrical conductivity of MgH2 has been studied under multishock compression. Earlier we had been experimentally studied metallization possibility of alane at high pressures in conditions quasiisentropic compression up to 100 GPa. A study of thermodynamic properties of MgH2 under multishock compression has been carried out also. High pressures and temperatures were obtained with an explosive device, which accelerates the metallic impactor up to 3 km/s. Identification of the hydride in experiments was made on the basis of calculations of phase trajectories loading a material in the area of existence of polymorphic phases including high-pressure phases of magnesium hydride (α and γ MgH2, hP1 and hP2). It is shown that occurrence of magnesium hydride electrical conductivity occurs in the field of existence of high-pressure hP2 phase This work was partially supported by the Presidium of the Russian Academy of Sciences within the Program of Basic Research ``Thermal Physics and Mechanics of Extreme Energy Effects and Physics of Strongly Compressed Matter and Russian Foundation for Basic Research Grant No. 10-02-01078.''

  18. The Application of the NFW Design Philosophy to the HSR Arrow Wing Configuration

    NASA Technical Reports Server (NTRS)

    Bauer, Steven X. S.; Krist, Steven E.

    1999-01-01

    The Natural Flow Wing design philosophy was developed for improving performance characteristics of highly-swept fighter aircraft at cruise and maneuvering conditions across the Mach number range (from Subsonic through Supersonic). The basic philosophy recognizes the flow characteristics that develop on highly swept wings and contours the surface to take advantage of those flow characteristics (e.g., forward facing surfaces in low pressure regions and aft facing surfaces in higher pressure regions for low drag). Because the wing leading edge and trailing edge have multiple sweep angles and because of shocks generated on nacelles and diverters, a viscous code was required to accurately define the surface pressure distributions on the wing. A method of generating the surface geometry to take advantage of those surface pressures (as well as not violating any structural constraints) was developed and the resulting geometries were analyzed and compared to a baseline configuration. This paper will include discussions of the basic Natural Flow Wing design philosophy, the application of the philosophy to an HSCT vehicle, and preliminary wind-tunnel assessment of the NFW HSCT vehicle.

  19. An experimental study of the validity of the heat-field concept for sonic-boom alleviation

    NASA Technical Reports Server (NTRS)

    Swigart, R. J.

    1974-01-01

    An experimental program was carried out in the NASA-Langley 4 ft x 4 ft supersonic pressure tunnel to investigate the validity of the heat-field concept for sonic boom alleviation. The concept involves heating the flow about a supersonic aircraft in such a manner as to obtain an increase in effective aircraft length and yield an effective aircraft shape that will result in a shock-free pressure signature on the ground. First, a basic body-of-revolution representing an SST configuration with its lift equivalence in volume was tested to provide a baseline pressure signature. Second, a model having a 5/2-power area distribution which, according to theory, should yield a linear pressure rise with no front shock wave was tested. Third, the concept of providing the 5/2-power area distribution by using an off-axis slender fin below the basic body was investigated. Then a substantial portion (approximately 40 percent) of the solid fin was replaced by a heat field generated by passing heated nitrogen through the rear of the fin.

  20. The effects of leading-edge serrations on reducing flow unsteadiness about airfoils, an experimental and analytical investigation

    NASA Technical Reports Server (NTRS)

    Schwind, R. G.; Allen, H. J.

    1973-01-01

    High frequency surface pressure measurements were obtained from wind-tunnel tests over the Reynolds number range 1.2 times one million to 6.2 times one million on a rectangular wing of NACA 63-009 airfoil section. Measurements were also obtained with a wide selection of leading-edge serrations added to the basic airfoil. Under a two-dimensional laminar bubble very close to the leading edge of the basic airfoil there is a large apatial peak in rms pressure. Frequency analysis of the pressure signals in this region show a large, high-frequency energy peak which is interpreted as an oscillation in size and position of the bubble. The serrations divide the bubble into segments and reduce the peak rms pressures. A low Reynolds number flow visualization test on a hydrofoil in water was also conducted. A von Karman vortex street was found trailing from the rear of the foil. Its frequency is at a much lower Strouhal number than in the high Reynolds number experiment, and is related to the trailing-edge and boundary-layer thicknesses.

  1. Management of raised intracranial pressure and hyperosmolar therapy.

    PubMed

    Ropper, Allan H

    2014-06-01

    The management of raised intracranial pressure is undergoing rapid change. The choice of medical treatments to reduce intracranial pressure varies between institutions and regions of the world. The mainstay of therapy, however, continues to be the infusion of a hyperosmolar solution to achieve an osmotic gradient to force the exit of water from the brain. This review introduces the basic concepts of raised intracranial pressure, summarises several recent studies that have challenged dogma in the field, and provides practical advice on hyperosmolar treatment, based on personal experience and a critical reading of the literature.

  2. Food webs and carbon flux in the Barents Sea

    NASA Astrophysics Data System (ADS)

    Wassmann, Paul; Reigstad, Marit; Haug, Tore; Rudels, Bert; Carroll, Michael L.; Hop, Haakon; Gabrielsen, Geir Wing; Falk-Petersen, Stig; Denisenko, Stanislav G.; Arashkevich, Elena; Slagstad, Dag; Pavlova, Olga

    2006-10-01

    Within the framework of the physical forcing, we describe and quantify the key ecosystem components and basic food web structure of the Barents Sea. Emphasis is given to the energy flow through the ecosystem from an end-to-end perspective, i.e. from bacteria, through phytoplankton and zooplankton to fish, mammals and birds. Primary production in the Barents is on average 93 g C m -2 y -1, but interannually highly variable (±19%), responding to climate variability and change (e.g. variations in Atlantic Water inflow, the position of the ice edge and low-pressure pathways). The traditional focus upon large phytoplankton cells in polar regions seems less adequate in the Barents, as the cell carbon in the pelagic is most often dominated by small cells that are entangled in an efficient microbial loop that appears to be well coupled to the grazing food web. Primary production in the ice-covered waters of the Barents is clearly dominated by planktonic algae and the supply of ice biota by local production or advection is small. The pelagic-benthic coupling is strong, in particular in the marginal ice zone. In total 80% of the harvestable production is channelled through the deep-water communities and benthos. 19% of the harvestable production is grazed by the dominating copepods Calanus finmarchicus and C. glacialis in Atlantic or Arctic Water, respectively. These two species, in addition to capelin ( Mallotus villosus) and herring ( Clupea harengus), are the keystone organisms in the Barents that create the basis for the rich assemblage of higher trophic level organisms, facilitating one of the worlds largest fisheries (capelin, cod, shrimps, seals and whales). Less than 1% of the harvestable production is channelled through the most dominating higher trophic levels such as cod, harp seals, minke whales and sea birds. Atlantic cod, seals, whales, birds and man compete for harvestable energy with similar shares. Climate variability and change, differences in recruitment, variable resource availability, harvesting restrictions and management schemes will influence the resource exploitation between these competitors, that basically depend upon the efficient energy transfer from primary production to highly successful, lipid-rich zooplankton and pelagic fishes.

  3. [Study of the supra-glottic pressure during partial constriction of the vocal tract].

    PubMed

    Suares, M; Cayrayre, F; Ouaknine, M; de la Brèteque, B Amy; Giovanni, A

    2004-01-01

    Phonation in a small plastic tube 22 cm length and 5 mms diameter (basic exercise of the method of Dr Amy de la Brèteque), is current practice in vocal rehabilitation in France. This work aims to show the effects of this method on the glottic vibration. The hypothesis was that at the time of phonation in the tube with a strong flow as recommended in the method, the vocal cords vibrate without contact. This limits the mechanical trauma at this level. We have analyzed the sound production in a tube in 11 trained and not trained subjects. We simultaneously collected the intra-oral air pressure and the vocal signal which was subjected to a spectral analysis. Spectral analysis confirmed that the signal was produced correctly i.e. with a strong flow and without interruption of the sound less rich in harmonics. We interpreted these results in the light of our preceding works on the glottic vibration and we show that this vocal production was of the sinusoidal type; this implies the absence of physical contact between the vocal cords, which validates our hypothesis. Further works are necessary to better understand the physical relations between the supra-glottic aerodynamic phenomena and the vibratory functioning of the vocal cords and also to analyze the therapeutic potential ofthe method within speech therapy rehabilitation.

  4. Global scientific research commons under the Nagoya Protocol: Towards a collaborative economy model for the sharing of basic research assets.

    PubMed

    Dedeurwaerdere, Tom; Melindi-Ghidi, Paolo; Broggiato, Arianna

    2016-01-01

    This paper aims to get a better understanding of the motivational and transaction cost features of building global scientific research commons, with a view to contributing to the debate on the design of appropriate policy measures under the recently adopted Nagoya Protocol. For this purpose, the paper analyses the results of a world-wide survey of managers and users of microbial culture collections, which focused on the role of social and internalized motivations, organizational networks and external incentives in promoting the public availability of upstream research assets. Overall, the study confirms the hypotheses of the social production model of information and shareable goods, but it also shows the need to complete this model. For the sharing of materials, the underlying collaborative economy in excess capacity plays a key role in addition to the social production, while for data, competitive pressures amongst scientists tend to play a bigger role.

  5. Efficient Hydrogen Storage and Production Using a Catalyst with an Imidazoline-Based, Proton-Responsive Ligand.

    PubMed

    Wang, Lin; Onishi, Naoya; Murata, Kazuhisa; Hirose, Takuji; Muckerman, James T; Fujita, Etsuko; Himeda, Yuichiro

    2017-03-22

    A series of new imidazoline-based iridium complexes has been developed for hydrogenation of CO 2 and dehydrogenation of formic acid. One of the proton-responsive complexes bearing two -OH groups at ortho and para positions on a coordinating pyridine ring (3 b) can catalyze efficiently the chemical fixation of CO 2 and release H 2 under mild conditions in aqueous media without using organic additives/solvents. Notably, hydrogenation of CO 2 can be efficiently carried out under CO 2 and H 2 at atmospheric pressure in basic water by 3 b, achieving a turnover frequency of 106 h -1 and a turnover number of 7280 at 25 °C, which are higher than ever reported. Moreover, highly efficient CO-free hydrogen production from formic acid in aqueous solution employing the same catalyst under mild conditions has been achieved, thus providing a promising potential H 2 -storage system in water. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite

    DOEpatents

    Tierney, J.W.; Wender, I.; Palekar, V.M.

    1995-01-24

    The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination comprising reduced copper chromite and basic alkali salts or alkaline earth salts. The present invention allows the synthesis of methanol to occur in the temperature range of approximately 100--160 C and the pressure range of 40--65 atm. The process produces methanol with up to 90% syngas conversion per pass and up to 95% methanol selectivity. The only major by-product is a small amount of easily separated methyl formate. Very small amounts of water, carbon dioxide and dimethyl ether are also produced. The present catalyst combination also is capable of tolerating fluctuations in the H[sub 2]/CO ratio without major deleterious effect on the reaction rate. Furthermore, carbon dioxide and water are also tolerated without substantial catalyst deactivation.

  7. Uptake of Alkylamines on Dicarboxylic Acids Relevant to Secondary Organic Aerosol Formation

    NASA Astrophysics Data System (ADS)

    Marrero-Ortiz, W.; Secrest, J.; Zhang, R.

    2017-12-01

    Aerosols play a critical role in climate directly by scattering and absorbing solar radiation, and indirectly by functioning as cloud condensation nuclei (CCN); both represent the largest uncertainties in climate predictions. New particle formation contributes significantly to CCN production; however, the mechanisms related to particle nucleation and growth processes are not well understood. Organic acids are atmospherically abundant, and their neutralization by low molecular weight amines may result in the formation of stable low volatility aminium salt products contributing to the growth of secondary organic aerosols and even the alteration of the aerosol properties. The acid-base neutralization of particle phase succinic acid and tartaric acid by low molecular weight aliphatic amines, i.e. methylamine, dimethylamine, and trimethylamine, has been investigated by employing a low-pressure fast flow reactor at 298K with an ion drift - chemical ionization mass spectrometer (ID-CIMS). The heterogeneous uptake is time dependent and influenced by organic acids functionality, alkylamines basicity, and steric effect. The implications of our results to atmospheric nanoparticle growth will be discussed.

  8. Efficient hydrogen storage and production using a catalyst with an imidazoline-based, proton-responsive ligand

    DOE PAGES

    Wang, Lin; Onishi, Naoya; Murata, Kazuhisa; ...

    2016-12-28

    A series of new imidazoline-based iridium complexes has been developed for hydrogenation of CO 2 and dehydrogenation of formic acid. One of the proton-responsive complexes bearing two –OH groups at ortho and para positions on a coordinating pyridine ring (3 b) can catalyze efficiently the chemical fixation of CO 2 and release H 2 under mild conditions in aqueous media without using organic additives/solvents. Notably, hydrogenation of CO 2 can be efficiently carried out under CO 2 and H 2 at atmospheric pressure in basic water by 3 b, achieving a turnover frequency of 106 h –1 and a turnovermore » number of 7280 at 25 °C, which are higher than ever reported. Furthermore, highly efficient CO-free hydrogen production from formic acid in aqueous solution employing the same catalyst under mild conditions has been achieved, thus providing a promising potential H 2-storage system in water.« less

  9. Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite

    DOEpatents

    Tierney, John W.; Wender, Irving; Palekar, Vishwesh M.

    1995-01-01

    The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination comprising reduced copper chromite and basic alkali salts or alkaline earth salts. The present invention allows the synthesis of methanol to occur in the temperature range of approximately 100.degree.-160.degree. C. and the pressure range of 40-65 atm. The process produces methanol with up to 90% syngas conversion per pass and up to 95% methanol selectivity. The only major by-product is a small amount of easily separated methyl formate. Very small amounts of water, carbon dioxide and dimethyl ether are also produced. The present catalyst combination also is capable of tolerating fluctuations in the H.sub.2 /CO ratio without major deleterious effect on the reaction rate. Furthermore, carbon dioxide and water are also tolerated without substantial catalyst deactivation.

  10. Methanol synthesis using a catalyst combination of alkali or alkaline earth salts and reduced copper chromite for methanol synthesis

    DOEpatents

    Tierney, John W.; Wender, Irving; Palekar, Vishwesh M.

    1993-01-01

    The present invention relates to a novel route for the synthesis of methanol, and more specifically to the production of methanol by contacting synthesis gas under relatively mild conditions in a slurry phase with a catalyst combination comprising reduced copper chromite and basic alkali salts or alkaline earth salts. The present invention allows the synthesis of methanol to occur in the temperature range of approximately 100.degree.-160.degree. C. and the pressure range of 40-65 atm. The process produces methanol with up to 90% syngas conversion per pass and up to 95% methanol selectivity. The only major by-product is a small amount of easily separated methyl formate. Very small amounts of water, carbon dioxide and dimethyl ether are also produced. The present catalyst combination also is capable of tolerating fluctuations in the H.sub.2 /CO ratio without major deleterious effect on the reaction rate. Furthermore, carbon dioxide and water are also tolerated without substantial catalyst deactivation.

  11. Western Shallow Oil Zone, Elk Hills Field, Kern County, California: General reservoir study, Appendix 3, Second Wilhelm Sand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carey, K.B.

    1987-09-01

    The general Reservoir Study of the Western Shallow Oil Zone was prepared by Evans, Carey and Crozier as Task Assignment 009 under Contract No. DE-ACO1-85FE60600 with the United States Department of Energy. This study Appendix III, the second Wilhelm Sand and it's sub units and pools. Basic pressure, production and assorted technical data were provided by the U.S. Department of Energy staff at Elk Hills. These data were accepted as furnished with no attempt being made by Evans, Carey and Crozier for independent verification. This study has identified the petrophysical properties and the past productive performance of the reservoir. Primarymore » reserves have been determined and general means of enhancing future recovery have been suggested. It is hoped that this volume can not additionally serve as a take off point for exploitation engineers to develop specific programs towards these ends. 15 figs., 9 tabs.« less

  12. The Connection between Employee Basic Skills & Productivity. Workforce & Workplace Literacy Series.

    ERIC Educational Resources Information Center

    BCEL Brief, 1993

    1993-01-01

    The experience of a number of specific local workplace programs indicates a definite connection between the provision of employee basic skills programs and increased worker productivity. One Tennessee company, for example, reports a 95 percent drop in costs resulting from worker mistakes and a doubling of worker productivity since the company…

  13. A Community Television Production Experience.

    ERIC Educational Resources Information Center

    Colorado State Univ., Ft. Collins. Dept. of Technical Journalism.

    The major goal of the Basic Video Production Workshop program of the Denver Community Video Center was to communicate basic production skills, through the use of extensive hands-on experience, to people with little or no training in the use of visual media. The ideas and exercises presented in this manual focus on the design and completion of…

  14. Effects of Inadequate Sleep on Blood Pressure and Endothelial Inflammation in Women: Findings From the American Heart Association Go Red for Women Strategically Focused Research Network.

    PubMed

    Aggarwal, Brooke; Makarem, Nour; Shah, Riddhi; Emin, Memet; Wei, Ying; St-Onge, Marie-Pierre; Jelic, Sanja

    2018-06-09

    Insufficient sleep increases blood pressure. However, the effects of milder, highly prevalent but frequently neglected sleep disturbances, including poor sleep quality and insomnia, on vascular health in women are unclear. We investigated whether poor sleep patterns are associated with blood pressure and endothelial inflammation in a diverse sample of women. Women who participated in the ongoing American Heart Association Go Red for Women Strategically Focused Research Network were studied (n=323, 57% minority, mean age=39±17 years, range=20-79 years). Sleep duration, sleep quality, and time to sleep onset were assessed using the Pittsburgh Sleep Quality Index (score ≥5=poor sleep quality). Risk for obstructive sleep apnea was evaluated using the Berlin questionnaire, and insomnia was assessed using the Insomnia Severity Index. In a subset of women who participated in the basic study (n=26), sleep duration was assessed objectively using actigraphy, and endothelial inflammation was assessed directly in harvested endothelial cells by measuring nuclear translocation of nuclear factor kappa B. Vascular reactivity was measured by brachial artery flow-mediated dilation (n=26). Systolic and diastolic blood pressure were measured by trained personnel (n=323). Multivariable linear regressions were used to evaluate associations between sleep patterns and blood pressure, nuclear factor kappa B, and flow-mediated dilation. Mean sleep duration was 6.8±1.3 hours/night in the population study and 7.5±1.1 hour/night in the basic study. In the population study sample, 50% had poor sleep quality versus 23% in the basic study, and 37% had some level of insomnia versus 15% in the basic study. Systolic blood pressure was associated directly with poor sleep quality, and diastolic blood pressure was of borderline significance with obstructive sleep apnea risk after adjusting for confounders ( P =0.04 and P =0.08, respectively). Poor sleep quality was associated with endothelial nuclear factor kappa B activation (β=30.6; P =0.03). Insomnia and longer sleep onset latency were also associated with endothelial nuclear factor kappa B activation (β=27.6; P =0.002 and β=8.26; P =0.02, respectively). No evidence was found for an association between sleep and flow-mediated dilation. These findings provide direct evidence that common but frequently neglected sleep disturbances such as poor sleep quality and insomnia are associated with increased blood pressure and vascular inflammation even in the absence of inadequate sleep duration in women. URL: https://www.clinicaltrials.gov. Unique identifier: NCT02835261. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  15. Steam tables for pure water as an ActiveX component in Visual Basic 6.0

    NASA Astrophysics Data System (ADS)

    Verma, Mahendra P.

    2003-11-01

    The IAPWS-95 formulation for the thermodynamic properties of pure water was implemented as an ActiveX component ( SteamTables) in Visual Basic 6.0. For input parameters as temperature ( T=190-2000 K) and pressure ( P=3.23×10 -8-10,000 MPa) the program SteamTables calculates the following properties: volume ( V), density ( D), compressibility factor ( Z0), internal energy ( U), enthalpy ( H), Gibbs free energy ( G), Helmholtz free energy ( A), entropy ( S), heat capacity at constant pressure ( Cp), heat capacity at constant volume ( Cv), coefficient of thermal expansion ( CTE), isothermal compressibility ( Ziso), velocity of sound ( VelS), partial derivative of P with T at constant V (d Pd T), partial derivative of T with V at constant P (d Td V), partial derivative of V with P at constant T (d Vd P), Joule-Thomson coefficient ( JTC), isothermal throttling coefficient ( IJTC), viscosity ( Vis), thermal conductivity ( ThrmCond), surface tension ( SurfTen), Prandtl number ( PrdNum) and dielectric constant ( DielCons) for the liquid and vapor phases of pure water. It also calculates T as a function of P (or P as a function of T) along the sublimation, saturation and critical isochor curves, depending on the values of P (or T). The SteamTables can be incorporated in a program in any computer language, which supports object link embedding (OLE) in the Windows environment. An application of SteamTables is illustrated in a program in Visual Basic 6.0 to tabulate the values of the thermodynamic properties of water and vapor. Similarly, four functions, Temperature(Press), Pressure(Temp), State(Temp, Press) and WtrStmTbls(Temp, Press, Nphs, Nprop), where Temp, Press, Nphs and Nprop are temperature, pressure, phase number and property number, respectively, are written in Visual Basic for Applications (VBA) to use the SteamTables in a workbook in MS-Excel.

  16. Incidence of Parental Support and Pressure on Their Children's Motivational Processes towards Sport Practice Regarding Gender.

    PubMed

    Amado, Diana; Sánchez-Oliva, David; González-Ponce, Inmaculada; Pulido-González, Juan José; Sánchez-Miguel, Pedro Antonio

    2015-01-01

    Grounded in Self-Determination Theory, structural equation modeling (SEM) with the aim of examining how parental support/pressure could influence their children´s motivational processes in sport was conducted, as well as the models´ differences in operability regarding gender. The sample size was 321 children ranging in age from 10 to 16 years old who were athletes from Extremadura, and 321 parents (included only the father or mother more involved with the sport of his or her child). 175 participants were male and 146 were female from individual (n = 130), and team sports (n=191). A questionnaire was conducted to assess parental perception of support/pressure and another questionnaire was conducted to measure satisfaction of basic psychological needs, type of motivation and enjoyment/boredom showed by their children towards sport practice. Results revealed that parental pressure negatively predicted satisfaction of the basic psychological needs. It also emerged as a strong positive predictor of intrinsic motivation and negative predictor of amotivation. Moreover, intrinsic motivation emerged as positive predictor of enjoyment and a negative predictor of boredom, whereas amotivation positively predicted boredom and negatively predicted enjoyment. Furthermore, results showed there were mean differences by gender: male athletes perceived greater parental pressure. Hence, it is necessary to decrease parental pressure towards their children in sport, with the aim of making them more motivated and enjoy, promoting positive consequences.

  17. Incidence of Parental Support and Pressure on Their Children’s Motivational Processes towards Sport Practice Regarding Gender

    PubMed Central

    Amado, Diana

    2015-01-01

    Grounded in Self-Determination Theory, structural equation modeling (SEM) with the aim of examining how parental support/pressure could influence their children´s motivational processes in sport was conducted, as well as the models´ differences in operability regarding gender. The sample size was 321 children ranging in age from 10 to 16 years old who were athletes from Extremadura, and 321 parents (included only the father or mother more involved with the sport of his or her child). 175 participants were male and 146 were female from individual (n = 130), and team sports (n=191). A questionnaire was conducted to assess parental perception of support/pressure and another questionnaire was conducted to measure satisfaction of basic psychological needs, type of motivation and enjoyment/boredom showed by their children towards sport practice. Results revealed that parental pressure negatively predicted satisfaction of the basic psychological needs. It also emerged as a strong positive predictor of intrinsic motivation and negative predictor of amotivation. Moreover, intrinsic motivation emerged as positive predictor of enjoyment and a negative predictor of boredom, whereas amotivation positively predicted boredom and negatively predicted enjoyment. Furthermore, results showed there were mean differences by gender: male athletes perceived greater parental pressure. Hence, it is necessary to decrease parental pressure towards their children in sport, with the aim of making them more motivated and enjoy, promoting positive consequences. PMID:26039062

  18. "Zero-Mass" Noninvasive Pressure Transducers

    NASA Technical Reports Server (NTRS)

    Hartley, Frank T.

    2009-01-01

    Extremely lightweight, compact, noninvasive, rugged, relatively inexpensive strain-gauge transducers have been developed for use in measuring pressures of fluids in tubes. These gauges were originally intended for measuring pressures of spacecraft-propulsion fluids, but they are also attractive for use in numerous terrestrial applications especially those involving fluids that are extremely chemically reactive, fluids that must be isolated for hygienic purposes, fluids that must be allowed to flow without obstruction, and fluid-containing tubes exposed to severe environments. A basic pressure transducer of this type comprises one or more pair(s) of thin-film strain gauges integral with a tube that contains the fluid of interest. Following established strain-gauge practice, the gauges in each pair are connected into opposite arms of a Wheatstone bridge (see figure). Typically, each pressure transducer includes one pair (the active pair) of strain gauges for measuring the hoop stress proportional to the pressure of the fluid in the tube and another pair (the dummy pair) of strain gauges that are nominally unstrained: The dummy gauges are mounted on a substrate that is made of the same material as that of the tube. The substrate is welded to the tube at only one spot so that stresses and strains are not coupled from the tube into the substrate. The dummy strain gauges measure neutral strains (basically, strains associated with thermal expansion), so that the neutral-strain contribution can be subtracted out of the final gauge reading.

  19. Education in Basic Skills and Training for Productive Work

    NASA Astrophysics Data System (ADS)

    Labarca, Guillermo

    1998-09-01

    The success of global policies and strategies aimed at training for productive work depends to a large extent on the level of development of basic skills among the work force and, likewise, training costs will vary according to the level of general preparation of those entering on the process. In view of the close relationship between the structure of the school system, the development of basic skills and actual training, different options are available to resolve imbalances between training for productive employment and previous basic education. Our conclusions are that training cannot replace basic education, that the process of technological change goes hand in hand with an increased demand for workers with a high level of education, that substituting training in specific skills for good basic education is not the most efficient option, and that one of the favorable effects of primary education is that it facilitates after- school training. This article seeks to identify certain dimensions of human resource training which are often overlooked in relation to both basic skills and specific training proper: namely, the imbalances existing between vocational training and previous education, and the options available for correcting them.

  20. Sensitivity of regional forest carbon budgets to continuous and stochastic climate change pressures

    NASA Astrophysics Data System (ADS)

    Sulman, B. N.; Desai, A. R.; Scheller, R. M.

    2010-12-01

    Climate change is expected to impact forest-atmosphere carbon budgets through three processes: 1. Increased disturbance rates, including fires, mortality due to pest outbreaks, and severe storms 2. Changes in patterns of inter-annual variability, related to increased incidence of severe droughts and defoliating insect outbreaks 3. Continuous changes in forest productivity and respiration, related to increases in mean temperature, growing season length, and CO2 fertilization While the importance of these climate change effects in future regional carbon budgets has been established, quantitative characterization of the relative sensitivity of forested landscapes to these different types of pressures is needed. We present a model- and- data-based approach to understanding the sensitivity of forested landscapes to climate change pressures. Eddy-covariance and biometric measurements from forests in the northern United States were used to constrain two forest landscape models. The first, LandNEP, uses a prescribed functional form for the evolution of net ecosystem productivity (NEP) over the age of a forested grid cell, which is reset following a disturbance event. This model was used for investigating the basic statistical properties of a simple landscape’s responses to climate change pressures. The second model, LANDIS-II, includes different tree species and models forest biomass accumulation and succession, allowing us to investigate the effects of more complex forest processes such as species change and carbon pool accumulation on landscape responses to climate change effects. We tested the sensitivity of forested landscapes to these three types of climate change pressures by applying ensemble perturbations of random disturbance rates, distribution functions of inter-annual variability, and maximum potential carbon uptake rates, in the two models. We find that landscape-scale net carbon exchange responds linearly to continuous changes in potential carbon uptake and inter-annual variability, while responses to stochastic changes are non-linear and become more important at shorter mean disturbance intervals. These results provide insight on how to better parameterize coupled carbon-climate models to more realistically simulate feedbacks between forests and the atmosphere.

  1. [Isn't the heart the source of energy for blood circulation? "The heart doesn't know the basic laws of physics"].

    PubMed

    Papp, Lajos

    2008-08-03

    For hundreds of years, universal medical practice has depicted the heart to be the central organ, showing the heart's function as the primary source of energy for blood circulation, paying particular importance to the role of the heart valves. At present the generally accepted paradigm: the main force component of blood circulation is the pressure-gradient generated by the working heart. In serious combined illnesses of heart valves, the function of the valve is almost nonexistent. Based on the value of pressure in the chambers of the heart and in the great arteries and veins, blood flows from a place of high pressure to lower pressure, and should work the other way around as well. It is a fact, however, that even in such cases the circulation of blood is directed from the main arteries towards the veins: without the function of the valves--seemingly opposing the basic laws of physics--it keeps its original direction. Therefore we can justifiably infer that it isn't the work of the heart muscle that provides the source of energy for blood circulation. The heart has an essential function in the maintenance of blood circulation: pulse generation. The principal role of the heart is to generate pulses and not pressure.

  2. Modeling internal ballistics of gas combustion guns.

    PubMed

    Schorge, Volker; Grossjohann, Rico; Schönekess, Holger C; Herbst, Jörg; Bockholdt, Britta; Ekkernkamp, Axel; Frank, Matthias

    2016-05-01

    Potato guns are popular homemade guns which work on the principle of gas combustion. They are usually constructed for recreational rather than criminal purposes. Yet some serious injuries and fatalities due to these guns are reported. As information on the internal ballistics of homemade gas combustion-powered guns is scarce, it is the aim of this work to provide an experimental model of the internal ballistics of these devices and to investigate their basic physical parameters. A gas combustion gun was constructed with a steel tube as the main component. Gas/air mixtures of acetylene, hydrogen, and ethylene were used as propellants for discharging a 46-mm caliber test projectile. Gas pressure in the combustion chamber was captured with a piezoelectric pressure sensor. Projectile velocity was measured with a ballistic speed measurement system. The maximum gas pressure, the maximum rate of pressure rise, the time parameters of the pressure curve, and the velocity and path of the projectile through the barrel as a function of time were determined according to the pressure-time curve. The maximum gas pressure was measured to be between 1.4 bar (ethylene) and 4.5 bar (acetylene). The highest maximum rate of pressure rise was determined for hydrogen at (dp/dt)max = 607 bar/s. The muzzle energy was calculated to be between 67 J (ethylene) and 204 J (acetylene). To conclude, this work provides basic information on the internal ballistics of homemade gas combustion guns. The risk of injury to the operator or bystanders is high, because accidental explosions of the gun due to the high-pressure rise during combustion of the gas/air mixture may occur.

  3. Bench to bedside: integrating advances in basic science into daily clinical practice.

    PubMed

    McGoldrick, Rory B; Hui, Kenneth; Chang, James

    2014-08-01

    This article focuses on the initial steps of commercial development of a patentable scientific discovery from an academic center through to marketing a clinical product. The basics of partnering with a technology transfer office (TTO) and the complex process of patenting are addressed, followed by a discussion on marketing and licensing the patent to a company in addition to starting a company. Finally, the authors address the basic principles of obtaining clearance from the Food and Drugs Administration, production in a good manufacturing practice (GMP) facility, and bringing the product to clinical trial. Published by Elsevier Inc.

  4. INCREASING HEAVY OIL RESERVES IN THE WILMINGTON OIL FIELD THROUGH ADVANCED RESERVOIR CHARACTERIZATION AND THERMAL PRODUCTION TECHNOLOGIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Hara

    2000-02-18

    The project involves using advanced reservoir characterization and thermal production technologies to improve thermal recovery techniques and lower operating and capital costs in a slope and basin clastic (SBC) reservoir in the Wilmington field, Los Angeles Co., CA. Through March 1999, project work has been completed related to data preparation, basic reservoir engineering, developing a deterministic three dimensional (3-D) geologic model, a 3-D deterministic reservoir simulation model, and a rock-log model, well drilling and completions, and surface facilities. Work is continuing on the stochastic geologic model, developing a 3-D stochastic thermal reservoir simulation model of the Fault Block IIA Tarmore » (Tar II-A) Zone, and operational work and research studies to prevent thermal-related formation compaction. Thermal-related formation compaction is a concern of the project team due to observed surface subsidence in the local area above the steamflood project. Last quarter on January 12, the steamflood project lost its inexpensive steam source from the Harbor Cogeneration Plant as a result of the recent deregulation of electrical power rates in California. An operational plan was developed and implemented to mitigate the effects of the two situations. Seven water injection wells were placed in service in November and December 1998 on the flanks of the Phase 1 steamflood area to pressure up the reservoir to fill up the existing steam chest. Intensive reservoir engineering and geomechanics studies are continuing to determine the best ways to shut down the steamflood operations in Fault Block II while minimizing any future surface subsidence. The new 3-D deterministic thermal reservoir simulator model is being used to provide sensitivity cases to optimize production, steam injection, future flank cold water injection and reservoir temperature and pressure. According to the model, reservoir fill up of the steam chest at the current injection rate of 28,000 BPD and gross and net oil production rates of 7,700 BPD and 750 BOPD (injection to production ratio of 4) will occur in October 1999. At that time, the reservoir should act more like a waterflood and production and cold water injection can be operated at lower net injection rates to be determined. Modeling runs developed this quarter found that varying individual well injection rates to meet added production and local pressure problems by sub-zone could reduce steam chest fill-up by up to one month.« less

  5. The Search for Carbonates on Mars

    NASA Technical Reports Server (NTRS)

    Farmer, Jack D.; DesMarais, David J.; Morrison, David (Technical Monitor)

    1994-01-01

    Liquid water is presently unstable at the Martian surface, where the mean atmospheric pressure is 6 mbar (due to CO2) and the winter diurnal temperature ranges from 150 K at the pole to 220 K at the equator. Liquid water is widely regarded as a basic requirement for living systems, suggesting that life as we know it is not possible in present surface environments on Mars. However, life may survive within "oases" where liquid water is present. Potential oases on Mars include subsurface hydrothermal systems or deeply buried aquifers where chemoautolithotrophic microorganisms may exist. Potential metabolic strategies for primary production in such environments on Mars (and for the microbial mediation of geologic processes!) encompass the full range presently known for subsurface environments on the Earth (e.g. sulphate reduction, methanogenesis, acetogenesis, etc).

  6. Effect of high pressure on growth and bacteriocin production of Pediococcus acidilactici HA-6111-2

    NASA Astrophysics Data System (ADS)

    Castro, S. M.; Kolomeytseva, M.; Casquete, R.; Silva, J.; Saraiva, J. A.; Teixeira, P.

    2015-10-01

    This study was aimed to investigate the effect of high pressure processing (HPP, 200-600 MPa) on the (i) survival of Listeria innocua and Pediococcus acidilactici HA-6111-2; (ii) production of bacteriocin bacHA-6111-2 and (iii) activity of bacteriocin against untreated and pressure-treated L. innocua cells. Inactivation of P. acidilactici was observed for pressures of >300 MPa. However, at this pressure level, L. innocua was more sensitive. Bacteriocin crude extract was pressure stable, with a decrease for pressures of ≥400 MPa. Pressures of ≤200 MPa did not affect bacteriocin production when compared with non-pressure-treated cells, whereas higher pressures caused a 2- to 4-fold decrease on the maximum level of bacteriocin production. Growth curves of P. acidilactici were fitted with the modified Gompertz model. The lag phase period depended on the magnitude of the pressure applied: there was a delay in the exponential phase as pressure increased and, as a consequence, in the beginning of bacteriocin production. Since P. acidilactici HA-6111-2 and its bacteriocin have shown resistance to pressures up to 300-400 MPa, they could be used in combination with HPP in order to improve food safety.

  7. Model-based estimation of adiabatic flame temperature during coal gasification

    NASA Astrophysics Data System (ADS)

    Sarigul, Ihsan Mert

    Coal gasification temperature distribution in the gasifier is one of the important issues. High temperature may increase the risk of corrosion of the gasifier wall or it may cause an increase in the amount of volatile compounds. At the same time, gasification temperature is a dominant factor for high conversion of products and completing the reactions during coal gasification in a short time. In the light of this information it can be said that temperature is one of key parameters of coal gasification to enhance the production of high heating value syngas and maximize refractory longevity. This study aims to predict the adiabatic flame temperatures of Australian bituminous coal and Indonesian roto coal in an entrained flow gasifier using different operating conditions with the ChemCAD simulation and design program. To achieve these objectives, two types of gasification parameters were carried out using simulation of a vertical entrained flow reactor: oxygen-to-coal feed ratio by kg/kg and pressure and steam-to-coal feed ratio by kg/kg and pressure. In the first part of study the adiabatic flame temperatures, coal gasification products and other coal characteristics of two types of coals were determined using ChemCAD software. During all simulations, coal feed rate, coal particle size, initial temperature of coal, water and oxygen were kept constant. The relationships between flame temperature, coal gasification products and operating parameters were fundamentally investigated. The second part of this study addresses the modeling of the flame temperature relation to methane production and other input parameters used previous chapter. The scope of this work was to establish a reasonable model in order to estimate flame temperature without any theoretical calculation. Finally, sensitivity analysis was performed after getting some basic correlations between temperature and input variables. According to the results, oxygen-to-coal feed ratio has the most influential effect on adiabatic flame temperature.

  8. MAGMIX: a basic program to calculate viscosities of interacting magmas of differing composition, temperature, and water content

    USGS Publications Warehouse

    Frost, T.P.; Lindsay, J.R.

    1988-01-01

    MAGMIX is a BASIC program designed to predict viscosities at thermal equilibrium of interacting magmas of differing compositions, initial temperatures, crystallinities, crystal sizes, and water content for any mixing proportion between end members. From the viscosities of the end members at thermal equilibrium, it is possible to predict the styles of magma interaction expected for different initial conditions. The program is designed for modeling the type of magma interaction between hypersthenenormative magmas at upper crustal conditions. Utilization of the program to model magma interaction at pressures higher than 200 MPa would require modification of the program to account for the effects of pressure on heat of fusion and magma density. ?? 1988.

  9. [Part II: basic hemodynamic monitoring and the use of pulmonary artery catheter].

    PubMed

    Dias, Fernando Suparregui; Rezende, Ederlon; Mendes, Ciro Leite; Réa-Neto, Alvaro; David, Cid Marcos; Schettino, Guilherme; Lobo, Suzana Margareth Ajeje; Barros, Alberto; Silva, Eliézer; Friedman, Gilberto; Amaral, José Luiz Gomes do; Park, Marcelo; Monachini, Maristela; Oliveira, Mirella Cristine de; Assunção, Murillo Santucci César; Akamine, Nelson; Mello, Patrícia Veiga C; Pereira, Renata Andréa Pietro; Costa Filho, Rubens; Araújo, Sebastião; Félix Pinto, Sérgio; Ferreira, Sérgio; Mitushima, Simone Mattoso; Agareno, Sydney; Brilhante, Yuzeth Nóbrega de Assis

    2006-03-01

    Monitoring of vital functions is one of the most important tools in the management of critically ill patients. Nowadays is possible to detect and analyze a great deal of physiologic data using a lot of invasive and non-invasive methods. The intensivist must be able to select and carry out the most appropriate monitoring technique according to the patient requirements and taking into account the benefit/risk ratio. Despite the fast development of non invasive monitoring techniques, invasive hemodynamic monitoring using Pulmonary Artery Catheter still is one of the basic procedures in Critical Care. The aim was to define recommendations about clinical utility of basic hemodynamic monitoring methods and the Use of Pulmonary Artery Catheter. Modified Delphi methodology was used to create and quantify the consensus between the participants. AMIB indicated a coordinator who invited more six experts in the area of monitoring and hemodynamic support to constitute the Consensus Advisory Board. Twenty-five physicians and nurses selected from different regions of the country completed the expert panel, which reviewed the pertinent bibliography listed at the MEDLINE in the period from 1996 to 2004. Recommendations were made based on 55 questions about the use of central venous pressure, invasive arterial pressure, pulmonary artery catheter and its indications in different settings. Evaluation of central venous pressure and invasive arterial pressure, besides variables obtained by the PAC allow the understanding of cardiovascular physiology that is of great value to the care of critically ill patients. However, the correct use of these tools is fundamental to achieve the benefits due to its use.

  10. A 'Quad-Disc' static pressure probe for measurement in adverse atmospheres - With a comparative review of static pressure probe designs

    NASA Astrophysics Data System (ADS)

    Nishiyama, Randall T.; Bedard, Alfred J., Jr.

    1991-09-01

    There are many areas of need for accurate measurements of atmospheric static pressure. These include observations of surface meteorology, airport altimeter settings, pressure distributions around buildings, moving measurement platforms, as well as basic measurements of fluctuating pressures in turbulence. Most of these observations require long-term observations in adverse environments (e.g., rain, dust, or snow). Currently, many pressure measurements are made, of necessity, within buildings, thus involving potential errors of several millibars in mean pressure during moderate winds, accompanied by large fluctuating pressures induced by the structure. In response to these needs, a 'Quad-Disk' pressure probe for continuous, outdoor monitoring purposes was designed which is inherently weather-protected. This Quad-Disk probe has the desirable features of omnidirectional response and small error in pitch. A review of past static pressure probes contrasts design approaches and capabilities.

  11. Pressure losses and heat transfer in non-circular channels with hydraulically smooth walls

    NASA Technical Reports Server (NTRS)

    Malak, J.

    1982-01-01

    The influence of channel geometry on pressure losses and heat transfer in noncircular channels with hydraulically smooth walls was studied. As a basic assumption for the description of this influence, integral geometrical criteria, selected according to experimental experience, were introduced. Using these geometrical criteria, a large set of experimental data for pressure losses and heat transfer in circular and annular channels with longitudinal fins was evaluated. In this way it as empirically proved that the criteria described channel geometry fairly well.

  12. Measurements of pressures on the wing of an aircraft model during steady rotation

    NASA Technical Reports Server (NTRS)

    Martin, Colin A.; Gage, Peter J.; Hultberg, Randy S.; Bowman, James S., Jr.

    1990-01-01

    An investigation has been conducted in the Spin Tunnel Facility at the NASA Langley Research Center to measure the pressures on the wing surfaces of a model of a Basic Training Aircraft during steady rotation. The tests were made to determine the nature of the wing pressure distribution during rotations typical of spin entry and steady spin. Comparisons are made between the forces and moments obtained from integrating the pressure field with those measured directly during rotary balance force tests. The results are also compared with estimates determined from a simple numerical model of the wing aerodynamic forces.

  13. Technetium-99m: basic nuclear physics and chemical properties.

    PubMed

    Castronovo, F P

    1975-05-01

    The nuclear physics and chemical properties of technetium-99m are reviewed. The review of basic nuclear physics includes: classification of nuclides, nuclear stability, production of radionuclides, artificial production of molybdenum-99, production of technetium 99m and -99Mo-99mTc generators. The discussion of the chemistry of technetium includes a profile of several -99mCc-labeled radiopharmaceuticals.

  14. Comparison of Engine/Inlet Distortion Measurements with MEMS and ESP Pressure Sensors

    NASA Technical Reports Server (NTRS)

    Soto, Hector L.; Hernandez, Corey D.

    2004-01-01

    A study of active-flow control in a small-scale boundary layer ingestion inlet was conducted at the NASA Langley Basic Aerodynamic Research Tunnel (BART). Forty MEMS pressure sensors, in a rake style configuration, were used to examine both the mean (DC) and high frequency (AC) components of the total pressure across the inlet/engine interface plane. The mean component was acquired and used to calculate pressure distortion. The AC component was acquired separately, at a high sampling rate, and is used to study the unsteady effects of the active-flow control. An identical total pressure rake, utilizing an Electronically Scanned Pressure (ESP) system, was also used to calculate distortion; a comparison of the results obtained using the two rakes is presented.

  15. Impact analysis of government investment on water projects in the arid Gansu Province of China

    NASA Astrophysics Data System (ADS)

    Wang, Zhan; Deng, Xiangzheng; Li, Xiubin; Zhou, Qing; Yan, Haiming

    In this paper, we introduced three-nested Constant Elasticity of Substitution (CES) production function into a static Computable General Equilibrium (CGE) Model. Through four levels of factor productivity, we constructed three nested production function of land use productivity in the conceptual modeling frameworks. The first level of factor productivity is generated by the basic value-added land. On the second level, factor productivity in each sector is generated by human activities that presents human intervention to the first level of factor productivity. On the third level of factor productivity, water allocation reshapes the non-linear structure of transaction among first and second levels. From the perspective of resource utilization, we examined the economic efficiency of water allocation. The scenario-based empirical analysis results show that the three-nested CES production function within CGE model is well-behaved to present the economy system of the case study area. Firstly, water scarcity harmed economic production. Government investment on water projects in Gansu thereby had impacts on economic outcomes. Secondly, huge governmental financing on water projects bring depreciation of present value of social welfare. Moreover, water use for environment adaptation pressures on water supply. The theoretical water price can be sharply increased due to the increasing costs of factor inputs. Thirdly, water use efficiency can be improved by water projects, typically can be benefited from the expansion of water-saving irrigation areas even in those expanding dry area in Gansu. Therefore, increasing governmental financing on water projects can depreciate present value of social welfare but benefit economic efficiency for future generation.

  16. Monitoring of Typical Steppe Desertification Based on Time Series of Net Primary Productivity Data

    NASA Astrophysics Data System (ADS)

    Wang, Hongyan; Li, Qiangzi; Gao, Zhihai

    2014-11-01

    Monitoring of grassland condition is a basic prerequisite for finding the degradation of a territory under climatic and human pressures leading to desertification. The temporal change in vegetation productivity is a key indicator of grassland degradation. In this paper, taking the Xilin Gol League as a case, the net primary production (NPP) dynamic trends during 2001-2010 were analyzed, with the Mann-Kendall test. In this paper, in the study area where precipitation and NPP has significantly positive correlation, the residual trend method (RESTREND) was used to remove the annual NPP fluctuation caused by rainfall fluctuation and reduce the effect of precipitation on vegetation monitoring indicators. The results showed that An overall strong liner correlation between NPP and precipitation was observed in the Xilin Gol grassland, with 68.52% of the pixels analyzed being significantly correlated (α =0.1). The statistical analysis reveals that the NPP trend estimation generally shows a decreasing trend, with 13.02% of the Xilin Gol grassland being analyzed showing a significant trend (11.47% decrease and 1.55% increase). However, the Xilin Gol grassland desertification was not serious in the past ten years, only 5.16% of the study area where the vegetation productivity was significantly decreases (reducing the effect of precipitation).

  17. Pressurized Structure Technology for UAVS

    DTIC Science & Technology

    2008-12-01

    deficiencies of the UAVs just listed is to employ lighter-than-air or pressurized structure-based ( PSB ) technology. Basically, the UAV will be built such...that a considerable percentage of its weight is supported by or constructed from inflatable structures containing air or helium. PSB technology...neutral buoyancy will allow much slower flight speeds and increased maneuverability while expending little power. PSB airframes used in conjunction

  18. Integrated rig for the production of boron nitride nanotubes via the pressurized vapor-condenser method

    DOEpatents

    Smith, Michael W; Jordan, Kevin C

    2014-03-25

    An integrated production apparatus for production of boron nitride nanotubes via the pressure vapor-condenser method. The apparatus comprises: a pressurized reaction chamber containing a continuously fed boron containing target having a boron target tip, a source of pressurized nitrogen and a moving belt condenser apparatus; a hutch chamber proximate the pressurized reaction chamber containing a target feed system and a laser beam and optics.

  19. Integrated Rig for the Production of Boron Nitride Nanotubes via the Pressurized Vapor-Condenser Method

    NASA Technical Reports Server (NTRS)

    Smith, Michael W. (Inventor); Jordan, Kevin C. (Inventor)

    2014-01-01

    An integrated production apparatus for production of boron nitride nanotubes via the pressure vapor-condenser method. The apparatus comprises: a pressurized reaction chamber containing a continuously fed boron containing target having a boron target tip, a source of pressurized nitrogen and a moving belt condenser apparatus; a hutch chamber proximate the pressurized reaction chamber containing a target feed system and a laser beam and optics.

  20. Method transfer from high-pressure liquid chromatography to ultra-high-pressure liquid chromatography. II. Temperature and pressure effects.

    PubMed

    Åsberg, Dennis; Samuelsson, Jörgen; Leśko, Marek; Cavazzini, Alberto; Kaczmarski, Krzysztof; Fornstedt, Torgny

    2015-07-03

    The importance of the generated temperature and pressure gradients in ultra-high-pressure liquid chromatography (UHPLC) are investigated and compared to high-pressure liquid chromatography (HPLC). The drug Omeprazole, together with three other model compounds (with different chemical characteristics, namely uncharged, positively and negatively charged) were used. Calculations of the complete temperature profile in the column at UHPLC conditions showed, in our experiments, a temperature difference between the inlet and outlet of 16 °C and a difference of 2 °C between the column center and the wall. Through van't Hoff plots, this information was used to single out the decrease in retention factor (k) solely due to the temperature gradient. The uncharged solute was least affected by temperature with a decrease in k of about 5% while for charged solutes the effect was more pronounced, with k decreases up to 14%. A pressure increase of 500 bar gave roughly 5% increase in k for the uncharged solute, while omeprazole and the other two charged solutes gave about 25, 20 and 15% increases in k, respectively. The stochastic model of chromatography was applied to estimate the dependence of the average number of adsorption/desorption events (n) and the average time spent by a molecule in the stationary phase (τs) on temperature and pressure on peak shape for the tailing, basic solute. Increasing the temperature yielded an increase in n and decrease in τs which resulted in less skew at high temperatures. With increasing pressure, the stochastic modeling gave interesting results for the basic solute showing that the skew of the peak increased with pressure. The conclusion is that pressure effects are more pronounced for both retention and peak shape than the temperature effects for the polar or charged compounds in our study. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Potential of membrane distillation for production of high quality fruit juice concentrate.

    PubMed

    Onsekizoglu Bagci, Pelin

    2015-01-01

    Fruit juices are generally concentrated in order to improve the stability during storage and to reduce handling, packaging, and transportation costs. Thermal evaporation is the most widely used technique in industrial fruit juice concentrate production. In addition to high energy consumption, a large part of the characteristics determining the quality of the fresh juice including aroma, color, vitamins, and antioxidants undergoes remarkable alterations through the use of high operation temperatures. Increasing consumer demand for minimally or naturally processed stable products able to retain as much possible the uniqueness of the fresh fruit has engendered a growing interest for development of nonthermal approaches for fruit juice concentration. Among them, membrane distillation (MD) and its variants have attracted much attention for allowing very high concentrations to be reached under atmospheric pressure and temperatures near ambient temperature. This review will provide an overview of the current status and recent developments in the use of MD for concentration of fruit juices. In addition to the most basic concepts of MD variants, crucial suggestions for membrane selection and operating parameters will be presented. Challenges and future trends for industrial adaptation taking into account the possibility of integrating MD with other existing processes will be discussed.

  2. 47 CFR 76.901 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... principal headend. (d) New Product Tier. A new product tier (“NPT”) is a cable programming service tier... CABLE TELEVISION SERVICE Cable Rate Regulation § 76.901 Definitions. (a) Basic service. The basic service tier shall, at a minimum, include all signals of domestic television broadcast stations provided...

  3. 47 CFR 76.901 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... principal headend. (d) New Product Tier. A new product tier (“NPT”) is a cable programming service tier... CABLE TELEVISION SERVICE Cable Rate Regulation § 76.901 Definitions. (a) Basic service. The basic service tier shall, at a minimum, include all signals of domestic television broadcast stations provided...

  4. 47 CFR 76.901 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... principal headend. (d) New Product Tier. A new product tier (“NPT”) is a cable programming service tier... CABLE TELEVISION SERVICE Cable Rate Regulation § 76.901 Definitions. (a) Basic service. The basic service tier shall, at a minimum, include all signals of domestic television broadcast stations provided...

  5. High-pressure anaerobic digestion up to 100 bar: influence of initial pressure on production kinetics and specific methane yields.

    PubMed

    Merkle, Wolfgang; Baer, Katharina; Haag, Nicola Leonard; Zielonka, Simon; Ortloff, Felix; Graf, Frank; Lemmer, Andreas

    2017-02-01

    To ensure an efficient use of biogas produced by anaerobic digestion, in some cases it would be advisable to upgrade the biogenic gases and inject them into the transnational gas grids. To investigate biogas production under high-pressure conditions up to 100 bar, new pressure batch methane reactors were developed for preliminary lab-scale experiments with a mixture of grass and maize silage hydrolysate. During this investigation, the effects of different initial pressures (1, 50 and 100 bar) on pressure increase, gas production and the specific methane yield using nitrogen as inert gas were determined. Based on the experimental findings increasing initial pressures alter neither significantly, further pressure increases nor pressure increase rates. All supplied organic acids were degraded and no measurable inhibition of the microorganisms was observed. The results show that methane reactors can be operated at operating pressures up to 100 bar without any negative effects on methane production.

  6. Enantioseparation of omeprazole--effect of different packing particle size on productivity.

    PubMed

    Enmark, Martin; Samuelsson, Jörgen; Forssén, Patrik; Fornstedt, Torgny

    2012-06-01

    Enantiomeric separation of omeprazole has been extensively studied regarding both product analysis and preparation using several different chiral stationary phases. In this study, the preparative chiral separation of omeprazole is optimized for productivity using three different columns packed with amylose tris (3,5-dimethyl phenyl carbamate) coated macroporous silica (5, 10 and 25 μm) with a maximum allowed pressure drop ranging from 50 to 400 bar. This pressure range both covers low pressure process systems (50-100 bar) and investigates the potential for allowing higher pressure limits in preparative applications in a future. The process optimization clearly show that the larger 25 μm packing material show higher productivity at low pressure drops whereas with increasing pressure drops the smaller packing materials have substantially higher productivity. Interestingly, at all pressure drops, the smaller packing material result in lower solvent consumption (L solvent/kg product); the higher the accepted pressure drop, the larger the gain in reduced solvent consumption. The experimental adsorption isotherms were not identical for the different packing material sizes; therefore all calculations were recalculated and reevaluated assuming identical adsorption isotherms (with the 10 μm isotherm as reference) which confirmed the trends regarding productivity and solvent consumption. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. Generation of region 1 current by magnetospheric pressure gradients

    NASA Technical Reports Server (NTRS)

    Yang, Y. S.; Spiro, R. W.; Wolf, R. A.

    1994-01-01

    The Rice Convection Model (RCM) is used to illustrate theoretical possibilities for generating region 1 Birkeland currents by pressure gradients on closed field lines in the Earth's magnetosphere. Inertial effects and viscous forces are neglected. The RCM is applied to idealized cases, to emphasize the basic physical ideas rather than realistic representation of the actual magnetosphere. Ionospheric conductance is taken to be uniform, and the simplest possible representations of the magnetospheric plasma are used. Three basic cases are considered: (1) the case of pure northward Interplanetary Magnetic Field (IMF), with cusp merging assumed to create new closed field lines near the nose of the magnetosphere, following the suggestion by Song and Russell (1992); (2) the case where Dungey-type reconnection occurs at the nose, but magnetosheath plasma somehow enters closed field lines on the dawnside and duskside of the merging region, causing a pressure-driven low-latitude boundary layer; and (3) the case where Dungey-type reconnection occurs at the nose, but region 1 currents flow on sunward drifting plasma sheet field lines. In case 1, currents of region 1 sense are generated by pressure gradients, but those currents do not supply the power for ionospheric convection. Results for case 2 suggest that pressure gradients at the inner edge of the low-latitude boundary layer might generate a large fraction of the region 1 Birkeland currents that drive magnetospheric convection. Results for case 3 indicate that pressure gradients in the plasma sheet could provide part of the region 1 current.

  8. The Next Marketing Handbook for Independent Schools.

    ERIC Educational Resources Information Center

    Cowan, Rick, Ed.

    Suggestions for marketing independent schools are presented in this handbook, which revolves around the basic marketing model of defining mission/strategy, using the "5 P's" (product/services, price, place, production/delivery, promotion) and monitoring. Chapters by 18 contributors offer information on the following topics: basic marketing theory,…

  9. Simulation and statistical analysis for the optimization of nitrogen liquefaction plant with cryogenic Claude cycle using process modeling tool: ASPEN HYSYS

    NASA Astrophysics Data System (ADS)

    Joshi, D. M.

    2017-09-01

    Cryogenic technology is used for liquefaction of many gases and it has several applications in food process engineering. Temperatures below 123 K are considered to be in the field of cryogenics. Extreme low temperatures are a basic need for many industrial processes and have several applications, such as superconductivity of magnets, space, medicine and gas industries. Several methods can be used to obtain the low temperatures required for liquefaction of gases. The process of cooling or refrigerating a gas to a temperature below its critical temperature so that liquid can be formed at some suitable pressure, which is below the critical pressure, is the basic liquefaction process. Different cryogenic cycle configurations are designed for getting the liquefied form of gases at different temperatures. Each of the cryogenic cycles like Linde cycle, Claude cycle, Kapitza cycle or modified Claude cycle has its own advantages and disadvantages. The placement of heat exchangers, Joule-Thompson valve and turboexpander decides the configuration of a cryogenic cycle. Each configuration has its own efficiency according to the application. Here, a nitrogen liquefaction plant is used for the analysis purpose. The process modeling tool ASPEN HYSYS can provide a software simulation approach before the actual implementation of the plant in the field. This paper presents the simulation and statistical analysis of the Claude cycle with the process modeling tool ASPEN HYSYS. It covers the technique used to optimize the liquefaction of the plant. The simulation results so obtained can be used as a reference for the design and optimization of the nitrogen liquefaction plant. Efficient liquefaction will give the best performance and productivity to the plant.

  10. Enhanced intestinal anastomotic healing with gelatin hydrogel incorporating basic fibroblast growth factor.

    PubMed

    Hirai, Kenjiro; Tabata, Yasuhiko; Hasegawa, Suguru; Sakai, Yoshiharu

    2016-10-01

    Anastomotic leakage is a common complication of intestinal surgery. In an attempt to resolve this issue, a promising approach is enhancement of anastomotic wound healing. A method for controlled release of basic fibroblast growth factor (bFGF) using a gelatin hydrogel was developed with the objective of investigating the effects of this technology on intestinal anastomotic healing. The small intestine of Wistar rats was cut, end-to-end anastomosis was performed and rats were divided into three groups: bFGF group (anastomosis wrapped with a hydrogel sheet incorporating bFGF), PBS group (wrapped with a sheet incorporating phosphate-buffered saline solution) and NT group (no additional treatment). Degradation profiles of gelatin hydrogels in vivo and histological examinations were performed using gelatin hydrogels with various water contents and bFGF concentrations to define the optimal bFGF dose and hydrogel biodegradability. The anastomotic wound healing process was evaluated by histological examinations, adhesion-related score and bursting pressure. The optimal water content of the hydrogel and bFGF dose was determined as 96% and 30 µg per sheet, respectively. Application of bFGF significantly enhanced neovascularization, fibroblast infiltration and collagen production around the anastomotic site when compared with the other groups. Bursting pressure was significantly increased in the bFGF group. No significant difference was observed in the adhesion-related score among the groups and no anastomotic obstruction and leakage were observed. Therefore controlled release of bFGF enhanced healing of an intestinal anastomosis during the early postoperative period and is a promising method to suppress anastomotic leakage. Copyright © 2013 John Wiley & Sons, Ltd. Copyright © 2013 John Wiley & Sons, Ltd.

  11. Separation of isotopes by cyclical processes

    DOEpatents

    Hamrin, Jr., Charles E.; Weaver, Kenny

    1976-11-02

    Various isotopes of hydrogen are separated by a cyclic sorption process in which a gas stream containing the isotopes is periodically passed through a high pressure column containing a palladium sorbent. A portion of the product from the high pressure column is passed through a second column at lower pressure to act as a purge. Before the sorbent in the high pressure column becomes saturated, the sequence is reversed with the stream flowing through the former low-pressure column now at high pressure, and a portion of the product purging the former high pressure column now at low pressure. The sequence is continued in cyclic manner with the product being enriched in a particular isotope.

  12. Speaking of food: connecting basic and applied plant science.

    PubMed

    Gross, Briana L; Kellogg, Elizabeth A; Miller, Allison J

    2014-10-01

    The Food and Agriculture Organization (FAO) predicts that food production must rise 70% over the next 40 years to meet the demands of a growing population that is expected to reach nine billion by the year 2050. Many facets of basic plant science promoted by the Botanical Society of America are important for agriculture; however, more explicit connections are needed to bridge the gap between basic and applied plant research. This special issue, Speaking of Food: Connecting Basic and Applied Plant Science, was conceived to showcase productive overlaps of basic and applied research to address the challenges posed by feeding billions of people and to stimulate more research, fresh connections, and new paradigms. Contributions to this special issue thus illustrate some interactive areas of study in plant science-historical and modern plant-human interaction, crop and weed origins and evolution, and the effects of natural and artificial selection on crops and their wild relatives. These papers provide examples of how research integrating the basic and applied aspects of plant science benefits the pursuit of knowledge and the translation of that knowledge into actions toward sustainable production of crops and conservation of diversity in a changing climate. © 2014 Botanical Society of America, Inc.

  13. Math on the Job. Metal Product Assembler.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This booklet is intended to help mainstreamed mentally retarded, emotionally disturbed, or learning disabled high school students acquire a basic understanding of the responsibilities and working conditions of metal product assemblers and to practice basic math skills necessary in the occupation. The first section provides a brief introduction to…

  14. High Pressure Earth Storable Rocket Technology Program: Basic Program

    NASA Technical Reports Server (NTRS)

    Chazen, M. L.; Sicher, D.; Huang, D.; Mueller, T.

    1995-01-01

    The HIPES Program was conducted for NASA-LeRC by TRW. The Basic Program consisted of system studies, design of testbed engine, fabrication and testing of engine. Studies of both pressure-fed and pump-fed systems were investigated for N2O4 and both MMH and N2H4 fuels with the result that N2H4 provides the maximum payload for all satellites over MMH. The higher pressure engine offers improved performance with smaller envelope and associated weight savings. Pump-fed systems offer maximum payload for large and medium weight satellites while pressure-fed systems offer maximum payload for small light weight satellites. The major benefits of HIPES are high performance within a confined length maximizing payload for lightsats which are length (volume) constrained. Three types of thrust chambers were evaluated -- Copper heatsink at 400, 500 and 600 psia chamber pressures for performance/thermal; water cooled to determine heat absorbed to predict rhenium engine operation; and rhenium to validate the concept. The HIPES engine demonstrated very high performance at 50 lbf thrust (epsilon = 150) and Pc = 500 psia with both fuels: Isp = 337 sec using N2O4-N2H4 and ISP = 327.5 sec using N2O4-MMH indicating combustion efficiencies greater than 98%. A powder metallurgy rhenium engine demonstrated operation with high performance at Pc = 500 psia which indicated the viability of the concept.

  15. Microbial production of metabolites and associated enzymatic reactions under high pressure.

    PubMed

    Dong, Yongsheng; Jiang, Hua

    2016-11-01

    High environmental pressure exerts an external stress on the survival of microorganisms that are commonly found under normal pressure. In response, many growth traits alter, including cell morphology and physiology, cellular structure, metabolism, physical and chemical properties, the reproductive process, and defense mechanisms. The high-pressure technology (HP) has been industrially utilized in pressurized sterilization, synthesis of stress-induced products, and microbial/enzymatic transformation of chemicals. This article reviews current research on pressure-induced production of metabolites in normal-pressure microbes and their enzymatic reactions. Factors that affect the production of such metabolites are summarized, as well as the effect of pressure on the performance of microbial fermentation and the yield of flavoring compounds, different categories of induced enzymatic reactions and their characteristics in the supercritical carbon dioxide fluid, effects on enzyme activity, and the selection of desirable bacterial strains. Technological challenges are discussed, and future research directions are proposed. Information presented here will benefit the research, development, and application of the HP technology to improve microbial fermentation and enzymatic production of biologically active substances, thereby help to meet their increasing demand from the ever-expanding market.

  16. PACS—Realization of an adaptive concept using pressure actuated cellular structures

    NASA Astrophysics Data System (ADS)

    Gramüller, B.; Boblenz, J.; Hühne, C.

    2014-10-01

    A biologically inspired concept is investigated which can be utilized to develop energy efficient, lightweight and applicational flexible adaptive structures. Building a real life morphing unit is an ambitious task as the numerous works in the particular field show. Summarizing fundamental demands and barriers regarding shape changing structures, the basic challenges of designing morphing structures are listed. The concept of Pressure Actuated Cellular Structures (PACS) is arranged within the recent morphing activities and it is shown that it complies with the underlying demands. Systematically divided into energy-related and structural subcomponents the working principle is illuminated and relationships between basic design parameters are expressed. The analytical background describing the physical mechanisms of PACS is presented in concentrated manner. This work focuses on the procedure of dimensioning, realizing and experimental testing of a single cell and a single row cantilever made of PACS. The experimental outcomes as well as the results from the FEM computations are used for evaluating the analytical methods. The functionality of the basic principle is thus validated and open issues are determined pointing the way ahead.

  17. RSRA sixth scale wind tunnel test. [of scale model of Sikorsky Whirlwind Helicopter

    NASA Technical Reports Server (NTRS)

    Flemming, R.; Ruddell, A.

    1974-01-01

    The sixth scale model of the Sikorsky/NASA/Army rotor systems research aircraft was tested in an 18-foot section of a large subsonic wind tunnel for the purpose of obtaining basic data in the areas of performance, stability, and body surface loads. The model was mounted in the tunnel on the struts arranged in tandem. Basic testing was limited to forward flight with angles of yaw from -20 to +20 degrees and angles of attack from -20 to +25 degrees. Tunnel test speeds were varied up to 172 knots (q = 96 psf). Test data were monitored through a high speed static data acquisition system, linked to a PDP-6 computer. This system provided immediate records of angle of attack, angle of yaw, six component force and moment data, and static and total pressure information. The wind tunnel model was constructed of aluminum structural members with aluminum, fiberglass, and wood skins. Tabulated force and moment data, flow visualization photographs, tabulated surface pressure data are presented for the basic helicopter and compound configurations. Limited discussions of the results of the test are included.

  18. Computer Modeling and Optimization of OBOGS with Contaminants

    DTIC Science & Technology

    1988-02-15

    respect to system parameters such as cycle time and bed and valve dimensions. _-- 20. DISTRIBUTION /AVAILABILITY OF ABSTRACT 21. ABSTRACT SECURITY...schematic (Solenoid valves are numbered 1 to 4 from the top) ..................................................... 46 Figure 12: Dual bed apparatus...most basic continuous PSA system is shown in Figure 1. Here a switching valve imposes supply pressure on Bed #1 and exhaust pressure on Bed #2. As the

  19. Investigating the effects of rock porosity and permeability on the performance of nitrogen injection into a southern Iranian oil reservoirs through neural network

    NASA Astrophysics Data System (ADS)

    Gheshmi, M. S.; Fatahiyan, S. M.; Khanesary, N. T.; Sia, C. W.; Momeni, M. S.

    2018-03-01

    In this work, a comprehensive model for Nitrogen injection into an oil reservoir (southern Iranian oil fields) was developed and used to investigate the effects of rock porosity and permeability on the oil production rate and the reservoir pressure decline. The model was simulated and developed by using ECLIPSE300 software, which involved two scenarios as porosity change and permeability changes in the horizontal direction. We found that the maximum pressure loss occurs at a porosity value of 0.07, which later on, goes to pressure buildup due to reservoir saturation with the gas. Also we found that minimum pressure loss is encountered at porosity 0.46. Increases in both pressure and permeability in the horizontal direction result in corresponding increase in the production rate, and the pressure drop speeds up at the beginning of production as it increases. However, afterwards, this pressure drop results in an increase in pressure because of reservoir saturation. Besides, we determined the regression values, R, for the correlation between pressure and total production, as well as for the correlation between permeability and the total production, using neural network discipline.

  20. Basic Pressure Measurements at Transonic Speeds on a Thin 45 deg Sweptback Highly Tapered Wing With Systematic Spanwise Twist Variations

    NASA Technical Reports Server (NTRS)

    Mugler, John P., Jr.

    1959-01-01

    Pressure distributions obtained in the Langley 8-foot transonic pressure tunnel on a thin, highly tapered, twisted, 45 deg sweptback wing in combination with a body are presented. The wing has a linear span-wise twist variation from 0 deg at 10 percent of the semispan to 6 deg at the tip. The tip is at a lower angle of attack than the root. Tests were made at stagnation pressures of 1.0 and 0.5 atmosphere, at Mach numbers from 0.800 to 1.200, and at angles of attack from -4 to 12 deg.

  1. Development of a new dynamic gas flow-control system in the pressure range of 1 Pa-133 Pa

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hong, S. S.; Chung, J. W.; Khan, Wakil

    2011-12-15

    A new flow-control system (FCS-705) has been developed at Korea Research Institute of Standards and Science. The system is intended for calibration of vacuum gauges in the pressure range of 1 Pa-133 Pa by comparison method. This paper describes some basic characteristics of the system including; (1) the design and construction of the system, (2) the generation of stable pressures in the chamber, (3) achieving high upstream pressure limit by installing a short duct in the by-pass pumping line, and (4) investigation of the gas flow regimes within the short duct.

  2. A compact model for electroosmotic flows in microfluidic devices

    NASA Astrophysics Data System (ADS)

    Qiao, R.; Aluru, N. R.

    2002-09-01

    A compact model to compute flow rate and pressure in microfluidic devices is presented. The microfluidic flow can be driven by either an applied electric field or a combined electric field and pressure gradient. A step change in the ζ-potential on a channel wall is treated by a pressure source in the compact model. The pressure source is obtained from the pressure Poisson equation and conservation of mass principle. In the proposed compact model, the complex fluidic network is simplified by an electrical circuit. The compact model can predict the flow rate, pressure distribution and other basic characteristics in microfluidic channels quickly with good accuracy when compared to detailed numerical simulation. Using the compact model, fluidic mixing and dispersion control are studied in a complex microfluidic network.

  3. Fundamentals of Acoustics. Psychoacoustics and Hearing. Acoustical Measurements

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Ahumada, Al (Technical Monitor)

    1997-01-01

    These are 3 chapters that will appear in a book titled "Building Acoustical Design", edited by Charles Salter. They are designed to introduce the reader to fundamental concepts of acoustics, particularly as they relate to the built environment. "Fundamentals of Acoustics" reviews basic concepts of sound waveform frequency, pressure, and phase. "Psychoacoustics and Hearing" discusses the human interpretation sound pressure as loudness, particularly as a function of frequency. "Acoustic Measurements" gives a simple overview of the time and frequency weightings for sound pressure measurements that are used in acoustical work.

  4. Applying Pressure Sensitive Paint Technology to Rotor Blades

    NASA Technical Reports Server (NTRS)

    Watkins, A. Neal; Leighty, Bradley D.; Lipford, William E.; Goodman, Kyle Z.; Crafton, Jim; Gregory, James W.

    2014-01-01

    This report will present details of a Pressure Sensitive Paint (PSP) system for measuring global surface pressures on rotorcrtaft blades in simulated forward flight at the 14- by 22-Foot Subsonic Tunnel at the NASA Langley Research Center. The basics of the PSP method will be discussed and the modifications that were needed to extend this technology for use on rotor blades. Results from a series of tests will also be presented as well as several areas of improvement that have been identified and are currently being developed for future testing.

  5. Subsonic wind-tunnel measurements of a slender wing-body configuration employing a vortex flap

    NASA Technical Reports Server (NTRS)

    Frink, Neal T.

    1987-01-01

    A wind tunnel study at Mach 0.4 was conducted for a slender wing-body configuration with a leading edge vortex flap of curved planform that is deflectable about a 74 degree swept hinge line. The basic data consist of a unique combination of longitudinal aerodynamic, surface pressure, and vortex flap hinge-moment measurements on a common model. The longitudinal aerodynamic, pressure and hinge-moment data are presented without analysis in tabular format. Plots of the tabulated pressure data are also given.

  6. Study of low gravity propellant transfer

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The results are presented of a program to perform an analytical assessment of potential methods for replenishing the auxiliary propulsion, fuel cell and life support cryogens which may be aboard an orbiting space station. The fluids involved are cryogenic H2, O2, and N2. A complete transfer system was taken to consist of supply storage, transfer, and receiver tank fluid conditioning (pressure and temperature control). In terms of supply storage, the basic systems considered were high pressure (greater than critical), intermediate pressure (less than critical), and modular (transfer of the tanks). Significant findings are included.

  7. Production of Nitrogen Oxides by Laboratory Simulated Transient Luminous Events

    NASA Astrophysics Data System (ADS)

    Peterson, H.; Bailey, M.; Hallett, J.; Beasley, W.

    2007-12-01

    Restoration of the polar stratospheric ozone layer has occurred at rates below those originally expected following reductions in chlorofluorocarbon (CFC) usage. Additional reactions affecting ozone depletion now must also be considered. This research examines nitrogen oxides (NOx) produced in the middle atmosphere by transient luminous events (TLEs), with NOx production in this layer contributing to the loss of stratospheric ozone. In particular, NOx produced by sprites in the mesosphere would be transported to the polar stratosphere via the global meridional circulation and downward diffusion. A pressure-controlled vacuum chamber was used to simulate middle atmosphere pressures, while a power supply and in-chamber electrodes were used to simulate TLEs in the pressure controlled environment. Chemiluminescence NOx analyzers were used to sample NOx produced by the chamber discharges- originally a Monitor Labs Model 8440E, later a Thermo Environment Model 42. Total NOx production for each discharge as well as NOx per ampere of current and NOx per Joule of discharge energy were plotted. Absolute NOx production was greatest for discharge environments with upper tropospheric pressures (100-380 torr), while NOx/J was greatest for discharge environments with stratospheric pressures (around 10 torr). The different production efficiencies in NOx/J as a function of pressure pointed to three different production regimes, each with its own reaction mechanisms: one for tropospheric pressures, one for stratospheric pressures, and one for upper stratospheric to mesospheric pressures (no greater than 1 torr).

  8. Synthesis and characterization of Co3O4 prepared from atmospheric pressure acid leach liquors of nickel laterite ores

    NASA Astrophysics Data System (ADS)

    Meng, Long; Guo, Zhan-cheng; Qu, Jing-kui; Qi, Tao; Guo, Qiang; Hou, Gui-hua; Dong, Peng-yu; Xi, Xin-guo

    2018-01-01

    A chemical precipitation-thermal decomposition method was developed to synthesize Co3O4 nanoparticles using cobalt liquor obtained from the atmospheric pressure acid leaching process of nickel laterite ores. The effects of the precursor reaction temperature, the concentration of Co2+, and the calcination temperature on the specific surface area, morphology, and the electrochemical behavior of the obtained Co3O4 particles were investigated. The precursor basic cobaltous carbonate and cobaltosic oxide products were characterized and analyzed by Fourier transform infrared spectroscopy, thermogravimetric differential thermal analysis, X-ray diffraction, field-emission scanning electron microscopy, specific surface area analysis, and electrochemical analysis. The results indicate that the specific surface area of the Co3O4 particles with a diameter of 30 nm, which were obtained under the optimum conditions of a precursor reaction temperature of 30°C, 0.25 mol/L Co2+, and a calcination temperature of 350°C, was 48.89 m2/g. Electrodes fabricated using Co3O4 nanoparticles exhibited good electrochemical properties, with a specific capacitance of 216.3 F/g at a scan rate of 100 mV/s.

  9. The physical characteristics of human proteins in different biological functions.

    PubMed

    Wang, Tengjiao; Tang, Hailin

    2017-01-01

    The physical properties of gene products are the foundation of their biological functions. In this study, we systematically explored relationships between physical properties and biological functions. The physical properties including origin time, evolution pressure, mRNA and protein stability, molecular weight, hydrophobicity, acidity/alkaline, amino acid compositions, and chromosome location. The biological functions are defined from 4 aspects: biological process, molecular function, cellular component and cell/tissue/organ expression. We found that the proteins associated with basic material and energy metabolism process originated earlier, while the proteins associated with immune, neurological system process etc. originated later. Tissues may have a strong influence on evolution pressure. The proteins associated with energy metabolism are double-stable. Immune and peripheral cell proteins tend to be mRNA stable/protein unstable. There are very few function items with double-unstable of mRNA and protein. The proteins involved in the cell adhesion tend to consist of large proteins with high proportion of small amino acids. The proteins of organic acid transport, neurological system process and amine transport have significantly high hydrophobicity. Interestingly, the proteins involved in olfactory receptor activity tend to have high frequency of aromatic, sulfuric and hydroxyl amino acids.

  10. The physical characteristics of human proteins in different biological functions

    PubMed Central

    Tang, Hailin

    2017-01-01

    The physical properties of gene products are the foundation of their biological functions. In this study, we systematically explored relationships between physical properties and biological functions. The physical properties including origin time, evolution pressure, mRNA and protein stability, molecular weight, hydrophobicity, acidity/alkaline, amino acid compositions, and chromosome location. The biological functions are defined from 4 aspects: biological process, molecular function, cellular component and cell/tissue/organ expression. We found that the proteins associated with basic material and energy metabolism process originated earlier, while the proteins associated with immune, neurological system process etc. originated later. Tissues may have a strong influence on evolution pressure. The proteins associated with energy metabolism are double-stable. Immune and peripheral cell proteins tend to be mRNA stable/protein unstable. There are very few function items with double-unstable of mRNA and protein. The proteins involved in the cell adhesion tend to consist of large proteins with high proportion of small amino acids. The proteins of organic acid transport, neurological system process and amine transport have significantly high hydrophobicity. Interestingly, the proteins involved in olfactory receptor activity tend to have high frequency of aromatic, sulfuric and hydroxyl amino acids. PMID:28459865

  11. Changes in predator exposure, but not in diet, induce phenotypic plasticity in scorpion venom.

    PubMed

    Gangur, Alex N; Smout, Michael; Liddell, Michael J; Seymour, Jamie E; Wilson, David; Northfield, Tobin D

    2017-09-27

    Animals embedded between trophic levels must simultaneously balance pressures to deter predators and acquire resources. Venomous animals may use venom toxins to mediate both pressures, and thus changes in this balance may alter the composition of venoms. Basic theory suggests that greater exposure to a predator should induce a larger proportion of defensive venom components relative to offensive venom components, while increases in arms races with prey will elicit the reverse. Alternatively, reducing the need for venom expenditure for food acquisition, for example because of an increase in scavenging, may reduce the production of offensive venom components. Here, we investigated changes in scorpion venom composition using a mesocosm experiment where we manipulated scorpions' exposure to a surrogate vertebrate predator and live and dead prey. After six weeks, scorpions exposed to surrogate predators exhibited significantly different venom chemistry compared with naive scorpions. This change included a relative increase in some compounds toxic to vertebrate cells and a relative decrease in some compounds effective against their invertebrate prey. Our findings provide, to our knowledge, the first evidence for adaptive plasticity in venom composition. These changes in venom composition may increase the stability of food webs involving venomous animals. © 2017 The Author(s).

  12. Plasma-water interactions at atmospheric pressure in a dc microplasma

    NASA Astrophysics Data System (ADS)

    Patel, Jenish; Němcová, Lucie; Mitra, Somak; Graham, William; Maguire, Paul; Švrček, Vladimir; Mariotti, Davide

    2013-09-01

    Plasma-liquid interactions generate a variety of chemical species that are very useful for the treatment of many materials and that makes plasma-induced liquid chemistry (PiLC) very attractive for industrial applications. The understanding of plasma-induced chemistry with water can open up a vast range of plasma-activated chemistry in liquid with enormous potential for the synthesis of chemical compounds, nanomaterials synthesis and functionalization. However, this basic understanding of the chemistry occurring at the plasma-liquid interface is still poor. In the present study, different properties of water are analysed when processed by plasma at atmospheric-pressure with different conditions. In particular, pH, temperature and conductivity of water are measured against current and time of plasma processing. We also observed the formation of molecular oxygen (O2) and hydrogen peroxide (H2O2) for the same plasma conditions. The current of plasma processing was found to affect the water properties and the production of hydrogen peroxide in water. The relation between the number of electrons injected from plasma in water and the number of H2O2 molecules was established and based on these results a scenario of reactions channels activated by plasma-water interface is concluded.

  13. Ozonolysis of α-phellandrene - Part 2: Compositional analysis of secondary organic aerosol highlights the role of stabilised Criegee intermediates

    NASA Astrophysics Data System (ADS)

    Mackenzie-Rae, Felix A.; Wallis, Helen J.; Rickard, Andrew R.; Pereira, Kelly L.; Saunders, Sandra M.; Wang, Xinming; Hamilton, Jacqueline F.

    2018-04-01

    The molecular composition of the water-soluble fraction of secondary organic aerosol (SOA) generated from the ozonolysis of α-phellandrene is investigated for the first time using high-pressure liquid chromatography coupled to high-resolution quadrupole-Orbitrap tandem mass spectrometry. In total, 21 prominent products or isomeric product groups were identified using both positive and negative ionisation modes, with potential formation mechanisms discussed. The aerosol was found to be composed primarily of polyfunctional first- and second-generation species containing one or more carbonyl, acid, alcohol and hydroperoxide functionalities, with the products significantly more complex than those proposed from basic gas-phase chemistry in the companion paper (Mackenzie-Rae et al., 2017). Mass spectra show a large number of dimeric products are also formed. Both direct scavenging evidence using formic acid and indirect evidence from double bond equivalency factors suggest the dominant oligomerisation mechanism is the bimolecular reaction of stabilised Criegee intermediates (SCIs) with non-radical ozonolysis products. Saturation vapour concentration estimates suggest monomeric species cannot explain the rapid nucleation burst of fresh aerosol observed in chamber experiments; hence, dimeric species are believed to be responsible for new particle formation, with detected first- and second-generation products driving further particle growth in the system. Ultimately, identification of the major constituents and formation pathways of α-phellandrene SOA leads to a greater understanding of the atmospheric processes and implications of monoterpene emissions and SCIs, especially around eucalypt forests where α-phellandrene is primarily emitted.

  14. Recent advances in bioprinting techniques: approaches, applications and future prospects.

    PubMed

    Li, Jipeng; Chen, Mingjiao; Fan, Xianqun; Zhou, Huifang

    2016-09-20

    Bioprinting technology shows potential in tissue engineering for the fabrication of scaffolds, cells, tissues and organs reproducibly and with high accuracy. Bioprinting technologies are mainly divided into three categories, inkjet-based bioprinting, pressure-assisted bioprinting and laser-assisted bioprinting, based on their underlying printing principles. These various printing technologies have their advantages and limitations. Bioprinting utilizes biomaterials, cells or cell factors as a "bioink" to fabricate prospective tissue structures. Biomaterial parameters such as biocompatibility, cell viability and the cellular microenvironment strongly influence the printed product. Various printing technologies have been investigated, and great progress has been made in printing various types of tissue, including vasculature, heart, bone, cartilage, skin and liver. This review introduces basic principles and key aspects of some frequently used printing technologies. We focus on recent advances in three-dimensional printing applications, current challenges and future directions.

  15. Understanding and Controlling Lignocellulosic Pyrolysis for the Production of Renewable Fuel and Chemical Precursors

    NASA Astrophysics Data System (ADS)

    Pecha, Michael Brennan

    Pyrolysis is a technology for producing fuels, chemicals, and engineered carbons from renewable feedstocks like lignocellulosic biomass. This work aims to address some of the scientific and technical hurdles that need to be overcome to control the products of pyrolysis. The first section aims to address knowledge gaps regarding primary pyrolysis reactions; in this study, pine wood was acid washed and small amounts of acid were impregnated into the biomass prior to pyrolysis. Results showed that the acid mitigated fragmentation reactions caused by residual metals and had further effect on production of sugars and oligomeric lignin products. The next section aims to address knowledge gaps regarding what reactions occur in the liquid intermediate phase in biomass pyrolysis; in these studies, a novel reactor system was built which could perform thin film fast pyrolysis studies at different pressures from 4 mbar to 1 atm with cellulose, milled wood lignin, and hybrid poplar wood. The reactor was carefully characterized to achieve comparable data between the different pressures. The use of vacuum allowed for control of the residence time of cellobiosan (one of cellulose oligomeric products) in the liquid intermediate. In the vacuum cellulose pyrolysis studies, a high resolution FT-ICR-MS was used for the first time to explore reaction chemistry for this system. The Van-Krevelen diagram of the resulting oligomeric products proved to be a powerful tool to study secondary reactions in the liquid intermediate. Our results show that the secondary reactions in the liquid intermediate are dominated by dehydration, fragmentation, and cross-linking reactions. The final section aims to address single particle external heat transfer problems; in this study, 500 microm long particles of pine and aspen poplar with realistic pore and surface morphologies were modeled in COMSOL to determine how microstructure effects the external heat transfer coefficients in the laminar flow regime. Results showed that microstructure did indeed affect heat transfer and that heat transfer correlations based on basic geometric shapes (sphere, cylinder, slab) were not accurate enough to estimate heat transfer coefficient for the conditions studied.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carlos-Pinedo, C.; Rodríguez-Vargas, I.; Martínez-Orozco, J. C.

    In this work we present the results obtained from the calculation of the level structure of a n-type delta-doped well Field Effect Transistor when is subjected to hydrostatic pressure. We study the energy level structure as a function of hydrostatic pressure within the range of 0 to 6 kbar for different Schottky barrier height (SBH). We use an analytical expression for the effect of hydrostatic pressure on the SBH and the pressure dependence of the basic parameters of the system as the effective mass m(P) and the dielectric constant ε(P) of GaAs. We found that due to the effects ofmore » hydrostatic pressure, in addition to electronic level structure alteration, the profile of the differential capacitance per unit area C{sup −2} is affected.« less

  17. Development of microbend sensors for pressure, load, and displacement measurements in civil engineering

    NASA Astrophysics Data System (ADS)

    Grossman, Barry G.; Cosentino, Paul J.; Doi, Shinobu; Kumar, Girish; Verghese, John

    1994-05-01

    We are developing low cost, rugged, and reliable fiberoptic sensors to meet current and future needs in civil engineering, including those of smart civil structures. Our work has concentrated on load, pressure, and displacement sensors, including pore water pressure sensors. We have built and demonstrated sensors in the laboratory with loads up to 50 lb., water pressures of 100 psi, and displacements up to 1 mm. Repeatability of sensor measurements are within 5% and are being improved with continued development. The range and sensitivity of the sensors can be easily changed without changing the basic sensor design. We also have multiplexed two water pressure sensors on a single fiber. We describe the sensor construction and experimental performance.

  18. Estimating vapor pressures of pure liquids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haraburda, S.S.

    1996-03-01

    Calculating the vapor pressures for pure liquid chemicals is a key step in designing equipment for separation of liquid mixtures. Here is a useful way to develop an equation for predicting vapor pressures over a range of temperatures. The technique uses known vapor pressure points for different temperatures. Although a vapor-pressure equation is being showcased in this article, the basic method has much broader applicability -- in fact, users can apply it to develop equations for any temperature-dependent model. The method can be easily adapted for use in software programs for mathematics evaluation, minimizing the need for any programming. Themore » model used is the Antoine equation, which typically provides a good correlation with experimental or measured data.« less

  19. Couple resilience to economic pressure.

    PubMed

    Conger, R D; Rueter, M A; Elder, G H

    1999-01-01

    Over 400 married couples participated in a 3-year prospective study of economic pressure and marital relations. The research (a) empirically evaluated the family stress model of economic stress influences on marital distress and (b) extended the model to include specific interactional characteristics of spouses hypothesized to protect against economic pressure. Findings provided support for the basic mediational model, which proposes that economic pressure increases risk for emotional distress, which, in turn, increases risk for marital conflict and subsequent marital distress. Regarding resilience to economic stress, high marital support reduced the association between economic pressure and emotional distress. In addition, effective couple problem solving reduced the adverse influence of marital conflict on marital distress. Overall, the findings provided substantial support for the extended family stress model.

  20. Pyrolytic oil of banana (Musa spp.) pseudo-stem via fast process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdullah, Nurhayati; Sulaiman, Fauziah; Taib, Rahmad Mohd

    This study was an attempt to produce bio-oil from banana pseudo-stem, a waste of banana cultivation, using fast pyrolysis technology. The compositions were determined and the thermal degradation behaviour of the raw material was analyzed using Perkin-Elmer Simultaneous Thermal Analyzer (STA) 6000. A 300 g/h fluidized bed bench scale fast pyrolysis unit, assembled with double screw feeders and cyclones, operating at atmospheric pressure, was used to obtain the pyrolysis liquid. The study involves the impact of the following key variables; the reactor temperature in the range of 450–650 °C, and the residence time in the range of 1.00–3.00 s. The particlemore » size was set at 224-400 µm. The properties of the liquid product were analyzed for calorific heating value, pH value, conductivity, water and char content. The basic functional groups of the compositions were also determined using FTIR. The properties of the liquid product were compared with other wood derived bio-oil. The pyrolysis liquids derived from banana pseudo-stem were found to be in an aqueous phase.« less

  1. Food for thought or thought for food?--a stakeholder dialogue around the role of the snacking industry in addressing the obesity epidemic.

    PubMed

    Astrup, A; Bovy, M W L; Nackenhorst, K; Popova, A E

    2006-08-01

    The current obesity epidemic is generally considered multi-causal. Certain foods, including snacks such as potato chips, and their marketing are often highlighted as needing particular attention. This forces potato chip producers to take position on their role and responsibility. Based on expert interviews and a literature review, a systems analysis approach is presented that distinguishes between basic physiology, self-control and what we call jam transmitters, signals and pressures from the environment that hinder or frustrate self-control. Examples of the latter are commercial push and seduction, obesogenic cultures, obesogenic physical environment, socioeconomic factors, genes, hormones and instincts. Solution of the epidemic demands an approach that involves all factors and all related actors. As for the snacking industry, the comprehensive responses are: to introduce specific diet products; to improve the nutritional quality of its products; the latter combined with supporting and engaging in healthy lifestyle marketing; to practice responsible targeting of marketing; and to limit the promotion of unhealthy consumption patterns.

  2. Anchoring of LPXTG-Like Proteins to the Gram-Positive Cell Wall Envelope.

    PubMed

    Siegel, Sara D; Reardon, Melissa E; Ton-That, Hung

    2017-01-01

    In Gram-positive bacteria, protein precursors with a signal peptide and a cell wall sorting signal (CWSS)-which begins with an LPXTG motif, followed by a hydrophobic domain and a tail of positively charged residues-are targeted to the cell envelope by a transpeptidase enzyme call sortase. Evolution and selective pressure gave rise to six classes of sortase, i.e., SrtA-F. Only class C sortases are capable of polymerizing substrates harboring the pilin motif and CWSS into protein polymers known as pili or fimbriae, whereas the others perform cell wall anchoring functions. Regardless of the products generated from these sortases, the basic principle of sortase-catalyzed transpeptidation is the same. It begins with the cleavage of the LPXTG motif, followed by the cross-linking of this cleaved product at the threonine residue to a nucleophile, i.e., an active amino group of the peptidoglycan stem peptide or the lysine residue of the pilin motif. This chapter will summarize the efforts to identify and characterize sortases and their associated pathways with emphasis on the cell wall anchoring function.

  3. A Case for Basic Rotating Detonation Engine Research

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.

    2016-01-01

    A brief review is provided covering the benefits to air breathing and chemical rocket propulsion found from pressure gain combustion in general, and rotating detonation in particular. Challenges are also identified.

  4. Hot tap thermowell installation

    NASA Technical Reports Server (NTRS)

    Romero, C. A.

    1971-01-01

    System permits valve housings or other fillings to be installed in live steam lines or water pipes without interrupting their operation, thus eliminating current tapping restrictions. Two basic assemblies for installation under pressure are described.

  5. Research, the lifeline of medicine.

    PubMed

    Kornberg, A

    1976-05-27

    Advances in medicine spring from discoveries in physics, chemistry and biology. Among key contributions to the diagnosis, treatment and prevention of cardiovascular and pulmonary diseases, a recent Comroe-Dripps analysis shows two thirds to have been basic rather than applied research. Without a firm foundation in basic knowledge innovations perceived as advances prove hollow and collapse. Strong social, economic and political pressures now threaten acquisition of basic knowledge. Scientists feel driven to undertake excessively complex problems and gamble against the historical record that science generally progresses by tackling discrete and well defined questions. Regardless of circumstances, professional standards require the physician and scientist to be creative and enlarge the fund of knowledge.

  6. Expendable Launch Vehicles Briefing and Basic Rocketry Physics

    NASA Technical Reports Server (NTRS)

    Delgado, Luis G.

    2010-01-01

    This slide presentation is composed of two parts. The first part shows pictures of launch vehicles and lift offs or in the case of the Pegasus launch vehicle separations. The second part discusses the basic physics of rocketry, starting with Newton's three physical laws that form the basis for classical mechanics. It includes a review of the basic equations that define the physics of rocket science, such as total impulse, specific impulse, effective exhaust velocity, mass ratio, propellant mass fraction, and the equations that combine to arrive at the thrust of the rocket. The effect of atmospheric pressure is reviewed, as is the effect of propellant mix on specific impulse.

  7. Stress-strain analysis of jejunal contractility in response to flow and ramp distension in type 2 diabetic GK rats: effect of carbachol stimulation.

    PubMed

    Zhao, Jingbo; Chen, Pengmin; Gregersen, Hans

    2013-09-27

    Investigation of intestinal motility in a genetic model of GK rats abandons the possible neurotoxic effect of streptozotocin in streptozotocin-induced diabetic model. Seven GK male rats (GK group) and nine normal Wistar rats (Normal group) were used in the study. The motility experiments were carried out in an organ bath containing physiological Krebs solution. Before and after 10(-5)M carbachol application, the pressure and diameter changes of jejunum were obtained in relation to (1) basic contraction, (2) flow-induced contraction with different outlet resistance pressures and (3) contractions induced by ramp distension. The frequency and amplitude of contractions were analyzed from pressure-diameter curves. Distension-induced contraction thresholds and maximum contraction amplitude of basic and flow-induced contractions were calculated in terms of stress and strain. (1) The contraction amplitude increased to the peak value in less than 10s after adding carbachol. More than two peaks were observed in the GK group. (2) Carbachol decreased the pressure and stress threshold and Young's modulus in the GK group (P<0.01). (3) Carbachol increased the maximum pressure and stress of flow-induced contractions at most outlet pressure levels in both two groups (P<0.001). Furthermore, the flow-induced contractions were significantly bigger at low outlet pressure levels in GK group (P<0.05 and P<0.01). (4) The contraction frequency, the strain threshold and the maximum contraction strain did not differ between the two groups (P>0.05) and between before and after carbachol application (P>0.05). In GK diabetic rats, the jejunal contractility was hypersensitive to flow and distension stimulation after carbachol application. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Density and pressure variability in the mesosphere and thermosphere

    NASA Technical Reports Server (NTRS)

    Davis, T. M.

    1986-01-01

    In an effort to isolate the essential physics of the mesosphere and the thermosphere, a steady one-dimensional density and pressure model has been developed in support of related NASA activities, i.e., projects such as the AOTV and the Space Station. The model incorporates a zeroth order basic state including both the three-dimensional wind field and its associated shear structure, etc. A first order wave field is also incorporated in period bands ranging from about one second to one day. Both basic state and perturbation quantities satsify the combined constraints of mass, linear momentum and energy conservation on the midlatitude beta plane. A numerical (iterative) technique is used to solve for the vertical wind which is coupled to the density and pressure fields. The temperature structure from 1 to 1000 km and the lower boundary conditions are specified using the U.S. Standard Atmosphere 1976. Vertical winds are initialized at the top of the Planetary Boundary Layer using Ekman pumping values over flat terrain. The model also allows for the generation of waves during the geostrophic adjustment process and incorporates wave nonlinearity effects.

  9. Effect of high-pressure on pine sawdust pyrolysis: Products distribution and characteristics

    NASA Astrophysics Data System (ADS)

    Xu, Baiqing; Li, Aimin

    2017-08-01

    In this work, the pressurized pyrolysis of pine sawdust was performed with a self-made pressurized pyrolysis reactor to investigatethe influence of pyrolysis pressure in the range of 0-5 MPa on products distribution and characteristics. The combustion feature and microstructure of bio-char had analyzed by thermogravimetric (TG) and scanning electron microscopy (SEM), respectively. Elemental analyzer and Fourier transform infrared spectroscopy (FTIR) were used to confirm the identities of bio-oil. The results indicated the pressure had a notable impact on the biomass pyrolysis, which promoted the secondary cracking of bio-oil to produce more gaseous products and bio-char. The minimum bio-oil yield of 20.24% was obtained at the pressure of 5 MPa. Furthermore, the pressure improved the products characteristics. The increasing of pressure was favour to the deoxygenation and dehydrogenation reactions of bio-oil, which led to the increase of CH4, H2 and CO2 in gas. At the same time, under the influence of pressure, the surface structure and compactedness of the bio-char were obviously improved.

  10. Supercritical Fluid Spray Application Process for Adhesives and Primers

    DTIC Science & Technology

    2003-03-01

    The basic scheme of SFE process consists of three steps. A solvent, typically carbon dioxide, first is heated and pressurized to a supercritical...passivation step to remove contaminants and to prevent recontamination. Bok et al. (25) describe a pressure pulsation mechanism to stimulate improved...in as a liquid, and then it is heated to above its critical temperature to become a supercritical fluid. The sample is injected and dissolved into

  11. Basic Technology of Squeeze-Film Dampers for Rotor Dynamics Control.

    DTIC Science & Technology

    1981-11-01

    IIonlmtllIom- $ n robeadnI 9 FiW.11(b) Dimensionlesis tangential force • anwteni ex it cow -tation values of le pressure ratio for a given e,. The two values...at every initant can be computed according to 14 .ey. S., Tarnoff. N. H., and Holstein , D.. DiThial CoWiptens Reynolds’ equation with the cavitation pressure imposed at Engeerinmn. Joumal of Lubcallion Technology

  12. Hierarchical poroelasticity: movement of interstitial fluid between porosity levels in bones.

    PubMed

    Cowin, Stephen C; Gailani, Gaffar; Benalla, Mohammed

    2009-09-13

    The governing equations for the theory of poroelastic materials with hierarchical pore space architecture and compressible constituents undergoing small deformations are developed. These equations are applied to the problem of determining the exchange of pore fluid between the vascular porosity (PV) and the lacunar-canalicular porosity (PLC) in bone tissue due to cyclic mechanical loading and blood pressure oscillations. The result is basic to the understanding of interstitial flow in bone tissue that, in turn, is basic to understanding of nutrient transport from the vasculature to the bone cells buried in the bone tissue and to the process of mechanotransduction by these cells. A formula for the volume of fluid that moves between the PLC and PV in a cyclic loading is obtained as a function of the cyclic mechanical loading and blood pressure oscillations. Formulas for the oscillating fluid pore pressure in both the PLC and the PV are obtained as functions of the two driving forces, the cyclic mechanical straining and the blood pressure, both with specified amplitude and frequency. The results of this study also suggest a PV permeability greater than 10(-9) m(2) and perhaps a little lower than 10(-8) m(2). Previous estimates of this permeability have been as small as 10(-14) m(2).

  13. Improved wound management by regulated negative pressure-assisted wound therapy and regulated, oxygen- enriched negative pressure-assisted wound therapy through basic science research and clinical assessment.

    PubMed

    Topaz, Moris

    2012-05-01

    Regulated negative pressure-assisted wound therapy (RNPT) should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last two decades. RNPT systems maintain the treated wound's environment as a semi-closed, semi-isolated system applying external physical stimulations to the wound, leading to biological and biochemical effects, with the potential to substantially influence wound-host interactions, and when properly applied may enhance wound healing. RNPT is a simple, safe, and affordable tool that can be utilized in a wide range of acute and chronic conditions, with reduced need for complicated surgical procedures, and antibiotic treatment. This technology has been shown to be effective and safe, saving limbs and lives on a global scale. Regulated, oxygen-enriched negative pressure-assisted wound therapy (RO-NPT) is an innovative technology, whereby supplemental oxygen is concurrently administered with RNPT for their synergistic effect on treatment and prophylaxis of anaerobic wound infection and promotion of wound healing. Understanding the basic science, modes of operation and the associated risks of these technologies through their fundamental clinical mechanisms is the main objective of this review.

  14. Quality characteristics of battered and fried chicken: comparison of pressure frying and conventional frying.

    PubMed

    Das, Rashmi; Pawar, Deepthi P; Modi, Vinod Kumar

    2013-04-01

    The marinated and battered chicken leg meat and breast meat were pressure fried and their physico-chemical qualities were compared to the conventional fried product (open pan deep fat frying). Shrinkage due to frying process was significantly lesser in case of pressure fried leg meat (PLM) and breast meat (PBM) as compared to products prepared by conventional frying leg meat (CLM) and breast meat (CBM). Also, juiciness of pressure fried chicken products was superior (p ≤ 0.05) than fried products obtained by the conventional method. PLM and PBM had lower fat content (p ≤ 0.05) compared to conventionally fried CLM and CBM. Lipid oxidation was higher (p ≤ 0.05) in conventional frying as compared to pressure frying. Irrespective of the type of chicken meat, conventionally fried meat required higher shear force as compared to pressure fried products. Salmonella, Staphylococcus aureus, Shigella and E. coli were not detected. The study indicates the usefulness and superiority of pressure frying in comparison to conventional deep fat frying.

  15. Hydrodynamic pressure processing: Impact on the quality attributes of fresh and further-processed meat products

    USDA-ARS?s Scientific Manuscript database

    This book chapter reviews hydrodynamic pressure processing (HDP) as an innovative, postharvest technology for enhancing the quality attributes of fresh and further-processed meat products. A variety of meat products have been tested for their response to the high pressure shockwaves of HDP. The st...

  16. Aerodynamic Characteristics at a Mach Number of 3.10 of Several Fourth-Stage Shapes of the Scout Research Vehicle

    NASA Technical Reports Server (NTRS)

    Jaquet, Byron M.

    1961-01-01

    A wind-tunnel investigation was made at a Mach number of 3.10 (Reynolds number per foot of 16.3 x 10(exp 6) to 16.9 x 10(exp 6)) to determine the aerodynamic characteristics of various modifications of the payload section of the fourth stage of the Scout research vehicle. It was found that, for the combination of stages 3 and 4, increasing the size of the nose of the basic Scout to provide a cylindrical section of the same diameter as the third stage increased the normal-force slope by about 30 percent, the axial force by about 39 percent, and moved the center of pressure forward by about one fourth-stage base diameter. By reducing the diameter of the cylinder, at about one nose length behind the base of the enlarged nose frustum, to that of the basic Scout and thereafter retaining the shape of the basic Scout, the center of pressure was moved rearward by about one-half fourth-stage base diameter at the expense of an additional 19-percent increase in axial force. A spike-hemisphere configuration had the largest forces and moments and the most forward center-of-pressure location of the configurations considered. Except for the axial force and pitching-moment slope, the experimental trends or magnitudes could not be estimated with the desired accuracy by Newtonian or-slender body theory.

  17. 16 CFR 1401.1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SELF PRESSURIZED... Product Safety Act (15 U.S.C. 2076(e)) for marketers and importers of self-pressurized consumer products... product stating that it contains a chlorofluorocarbon that may harm the public health and environment by...

  18. 16 CFR 1401.1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SELF PRESSURIZED... Product Safety Act (15 U.S.C. 2076(e)) for marketers and importers of self-pressurized consumer products... product stating that it contains a chlorofluorocarbon that may harm the public health and environment by...

  19. 16 CFR 1401.1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SELF PRESSURIZED... Product Safety Act (15 U.S.C. 2076(e)) for marketers and importers of self-pressurized consumer products... product stating that it contains a chlorofluorocarbon that may harm the public health and environment by...

  20. On the use of thick-airfoil theory to design airfoil families in which thickness and lift are varied independently

    NASA Technical Reports Server (NTRS)

    Barger, R. L.

    1974-01-01

    A method has been developed for designing families of airfoils in which the members of a family have the same basic type of pressure distribution but vary in thickness ratio or lift, or both. Thickness ratio and lift may be prescribed independently. The method which is based on the Theodorsen thick-airfoil theory permits moderate variations from the basic shape on which the family is based.

  1. Pressure distribution on the roof of a model low-rise building tested in a boundary layer wind tunnel

    NASA Astrophysics Data System (ADS)

    Goliber, Matthew Robert

    With three of the largest metropolitan areas in the United States along the Gulf coast (Houston, Tampa, and New Orleans), residential populations ever increasing due to the subtropical climate, and insured land value along the coast from Texas to the Florida panhandle greater than $500 billion, hurricane related knowledge is as important now as ever before. This thesis focuses on model low-rise building wind tunnel tests done in connection with full-scale low-rise building tests. Mainly, pressure data collection equipment and methods used in the wind tunnel are compared to pressure data collection equipment and methods used in the field. Although the focus of this report is on the testing of models in the wind tunnel, the low-rise building in the field is located in Pensacola, Florida. It has a wall length of 48 feet, a width of 32 feet, a height of 10 feet, and a gable roof with a pitch of 1:3 and 68 pressure ports strategically placed on the surface of the roof. Built by Forest Products Laboratory (FPL) in 2002, the importance of the test structure has been realized as it has been subjected to numerous hurricanes. In fact, the validity of the field data is so important that the following thesis was necessary. The first model tested in the Bill James Wind Tunnel for this research was a rectangular box. It was through the testing of this box that much of the basic wind tunnel and pressure data collection knowledge was gathered. Knowledge gained from Model 1 tests was as basic as how to: mount pressure tubes on a model, use a pressure transducer, operate the wind tunnel, utilize the pitot tube and reference pressure, and measure wind velocity. Model 1 tests also showed the importance of precise construction to produce precise pressure coefficients. Model 2 was tested in the AABL Wind Tunnel at Iowa State University. This second model was a 22 inch cube which contained a total of 11 rows of pressure ports on its front and top faces. The purpose of Model 2 was to validate the tube length, tube diameter, port diameter, and pressure transducer used in the field. Also, Model 2 was used to study the effects of surface roughness on pressure readings. A partial roof and wall of the low-rise building in the field was used as the third model. Similar to the second model, Model 3 was tested in the AABL Wind Tunnel. Initially, the objectives of the third model were to validate the pressure port protection device (PPPD) being used in the field and test the possibility of interpolating between pressure ports. But in the end, Model 3 was best used to validate the inconsistencies of the full-scale PPPD, validate the transducers used in the field, and prove the importance of scaling either all or none of the model. Fourthly, Model 4 was a 1:16 model of the low-rise building itself. Based on the three previous model tests, Model 4 was instrumented with 202 pressure transducers to better understand: (1) the pressure distribution on the roof of the structure, (2) the affects of the fundamental test variables such as tube length, tube diameter, port diameter, transducer type, and surface roughness, (3) the affects of a scaled PPPD, (4) the importance of wind angle of attack, and (5) the possibility of measuring pressure data and load data simultaneously. In the end, the combination of all four model tests proved to be helpful in understanding the pressure data gathered on the roof of the low-rise building in the field. The two main recommendations for the field structure are for reevaluation of the PPPD design and slight redistribution of the pressure ports. The wind tunnel model tests show a need for these two modifications in order to gather more accurate field pressure data. Other than these two adjustments, the model tests show that the remaining data gathering system is currently accurate.

  2. Replicating a survey of pressure ulcer content in nursing textbooks.

    PubMed

    Ayello, Elizabeth A; Meaney, Geraldine

    2003-09-01

    Nurses enter the profession with knowledge about pressure ulcer prevention and care and acquired from their basic educational programs. A prior review of nursing textbooks regarding pressure ulcer content published almost a decade ago revealed that incomplete, inaccurate, and at times limited information (as few as 200 lines of text) was contained in 10 commonly used textbooks. A review of the updated editions of the textbooks revealed a wide variation in the number of lines of text devoted to pressure ulcers, depth and quality of information, and the number of illustrations and tables. New findings were the inclusion of cultural concepts and research studies. These findings suggest an improvement in the amount and quality of pressure ulcer information in the majority of nursing textbooks surveyed. Recommendations for future textbook chapters on pressure ulcers are provided.

  3. Project Economic Stew: A Study of Poultry and Rice. A Third-grade Economics Project [and] A Bird's Eye View of an Economic Stew: A Study of Poultry and Rice Production in Arkansas.

    ERIC Educational Resources Information Center

    Fox, Penny

    An economics project for third grade children is described and lessons for teaching basic economic concepts are provided. In the first semester, students studied basic economic concepts; in the second semester, they learned about the origin, production, and distribution of rice and poultry and how these products affect the local and state…

  4. Estimating the irreversible pressure drop across a stenosis by quantifying turbulence production using 4D Flow MRI

    PubMed Central

    Ha, Hojin; Lantz, Jonas; Ziegler, Magnus; Casas, Belen; Karlsson, Matts; Dyverfeldt, Petter; Ebbers, Tino

    2017-01-01

    The pressure drop across a stenotic vessel is an important parameter in medicine, providing a commonly used and intuitive metric for evaluating the severity of the stenosis. However, non-invasive estimation of the pressure drop under pathological conditions has remained difficult. This study demonstrates a novel method to quantify the irreversible pressure drop across a stenosis using 4D Flow MRI by calculating the total turbulence production of the flow. Simulation MRI acquisitions showed that the energy lost to turbulence production can be accurately quantified with 4D Flow MRI within a range of practical spatial resolutions (1–3 mm; regression slope = 0.91, R2 = 0.96). The quantification of the turbulence production was not substantially influenced by the signal-to-noise ratio (SNR), resulting in less than 2% mean bias at SNR > 10. Pressure drop estimation based on turbulence production robustly predicted the irreversible pressure drop, regardless of the stenosis severity and post-stenosis dilatation (regression slope = 0.956, R2 = 0.96). In vitro validation of the technique in a 75% stenosis channel confirmed that pressure drop prediction based on the turbulence production agreed with the measured pressure drop (regression slope = 1.15, R2 = 0.999, Bland-Altman agreement = 0.75 ± 3.93 mmHg). PMID:28425452

  5. Lesson Plans for Teaching Basic Vocational Agriculture. Section II. Introduction to Livestock Production.

    ERIC Educational Resources Information Center

    McCully, James S., Jr., Comp.

    This volume, the second in a series of five publications for use in teaching basic vocational agriculture in Mississippi secondary schools, consists of the final eight lessons in a 15-lesson introduction to livestock production. Covered in the individual lessons included in this volume are the following topics: types of livestock production…

  6. 16 CFR Figure 2 to Part 1203 - ISO Headform-Basic, Reference, and Median Planes

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false ISO Headform-Basic, Reference, and Median Planes 2 Figure 2 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 2 Figure 2 to Part 1203—ISO...

  7. Computer simulation of CaSiO3 glass under compression: correlation between Si-Si pair radial distribution function and intermediate range order structure

    NASA Astrophysics Data System (ADS)

    Lan, Mai Thi; Thuy Duong, Tran; Iitaka, Toshiaki; Van Hong, Nguyen

    2017-06-01

    The structural organization of CaSiO3 glass at 600 K and under pressure of 0-100 GPa is investigated by molecular dynamics simulation (MDS). Results show that the atomic structure of CaSiO3 comprises SiO n and CaO m units considered as basic structural polyhedra. At low pressure, most of the basic structural polyhedra are SiO4, CaO5, CaO6 and CaO7. At high pressure most of the basic structural polyhedra are SiO5, SiO6 and CaO9, CaO10 and CaO11. The distribution of basic structural polyhedra is not uniform resulting in formation of Ca-rich and Si-rich regions. The distribution of SiO4, SiO5 and SiO6 polyhedra is also not uniform, but it tends to form SiO4-, SiO5-, and SiO6-clusters. For the Si-O network, under compression there is a gradual transition from the tetrahedral network (SiO4) to the octahedral network (SiO6) via SiO5 polyhedra. The SiO5-clusters are the same as immediate-phase in the transformation process. The size and shape of SiO4 tetrahedra change strongly under compression. While the size of SiO5 and SiO6 has also changed significantly, but the shape is almost unchanged under compression. The SiO n polyhedra can connect to each other via one common oxygen ion (corner-sharing bond), two common oxygen ions (edge-sharing bond) or three common oxygen ions (face-sharing bond). The Si-Si bond length in corner-sharing bonds is much longer than the ones in edge-sharing and face-sharing bonds. The change of intermediate range order (IRO) structure under compression relating to edge- and face-sharing bonds amongst SiO n at high pressure is the origin of the first peak splitting of the radial distribution functions of Si-Si pair. Under compression, the number of non-bridging oxygen (NBO) decreases. This makes the Si-O network more polymerized. At low pressure, most of the Ca2+ ions incorporate into the Si-O network via NBOs. At high pressure, the amount of NBO decreases, Ca2+ ions mainly incorporate into the Si-O network via bridging oxygen (BO) that belongs to SiO5 and SiO6 with a negative charge. And this is the principle for immobilization of heavy metal as well as fissile materials in hazardous waste (nuclear waste).

  8. Conversion of vegetable oils and animal fats into paraffinic cetane enhancers for diesel fuels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wong, A.; Feng, Y.; Hogan, E.

    1995-11-01

    The two principal methods of producing biodiesel fuels are (a) transesterification of vegetable oils and animal fats with a monohydric alcohol, and (b) direct hydrotreating of tree oils, vegetable oils and animal fats. The patented hydrotreating technology is based on the catalytic processing of biomass oils and fats with hydrogen, under elevated temperature and pressure conditions. The typical mix of hydrotreated products is as follows: 5-15% light distillate (naphta), 40-60% middle distillate (cetane), 5-15% heavy distillate and 5-10% burner gas. The naptha fraction may be used as a gasoline supplement. The middle distillate is designed for use as a cetanemore » booster for diesel fuels. Both heavy distillate and light hydrocarbon gases are usable as power boiler fuels. Typically, the cetane enhancer would be admixed with diesel fuel in the range of 5 to 30% by volume. This new diesel blend meets the essential quality characteristics of the basic diesel fuel, for direct use in diesel engines without any modifications. The basic hydrotreatment technology has been evaluated further in the laboratory on degummed soya oil, yellow grease and animal tallow. The preliminary findings suggest that the technology can provide efficient conversion of these materials into cetane enhancers for diesel fuels.« less

  9. Behavior of lysozyme adsorbed onto biological liquid crystal lipid monolayer at the air/water interface

    NASA Astrophysics Data System (ADS)

    Lu, Xiaolong; Shi, Ruixin; Hao, Changchun; Chen, Huan; Zhang, Lei; Li, Junhua; Xu, Guoqing; Sun, Runguang

    2016-09-01

    The interaction between proteins and lipids is one of the basic problems of modern biochemistry and biophysics. The purpose of this study is to compare the penetration degree of lysozyme into 1,2-diapalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphoethano-lamine (DPPE) by analyzing the data of surface pressure-area (π-A) isotherms and surface pressure-time (π-T) curves. Lysozyme can penetrate into both DPPC and DPPE monolayers because of the increase of surface pressure at an initial pressure of 15 mN/m. However, the changes of DPPE are larger than DPPC, indicating stronger interaction of lysozyme with DPPE than DPPC. The reason may be due to the different head groups and phase state of DPPC and DPPE monolayers at the surface pressure of 15 mN/m. Atomic force microscopy reveals that lysozyme was absorbed by DPPC and DPPE monolayers, which leads to self-aggregation and self-assembly, forming irregular multimers and conical multimeric. Through analysis, we think that the process of polymer formation is similar to the aggregation mechanism of amyloid fibers. Project supported by the National Natural Science Foundation of China (Grant Nos. 21402114 and 11544009), the Natural Science Basic Research Plan in Shaanxi Province of China (Grant No. 2016JM2010), the Fundamental Research Funds for the Central Universities of China (Grant No. GK201603026), and the National University Science and Technology Innovation Project of China (Grant No. 201610718013).

  10. Basic or extended urine sampling to analyse urine production?

    PubMed

    Denys, Marie-Astrid; Kapila, Vansh; Weiss, Jeffrey; Goessaert, An-Sofie; Everaert, Karel

    2017-09-01

    Frequency volume charts are valuable tools to objectify urine production in patients with nocturia, enuresis or nocturnal incontinence. Analyses of daytime and nighttime urine (=basic collection) or analyses of urine samples collected every 3 h (=extended collection) extend this evaluation by describing circadian patterns of water and solute diuresis (=renal function profiles). To assess intra-individual correlation and agreement between renal function profiles provided using basic and extended urine collections, and using two extended urine collections. To create a short-form of the extended collection. This prospective observational study was executed at Ghent University Hospital, Belgium. Study participation was open for anyone visiting the hospital. Participants collected one basic and two extended 24-h urine collections. Urinary levels of osmolality, sodium and creatinine were determined. There was a moderate to strong correlation between results of basic and extended urinalyses. Comparing both extended urinalyses showed a moderate correlation between the eight individual samples and a weak to strong correlation between the mean daytime and nighttime values of renal functions. Different samples could be considered as most representative for mean daytime values, while all samples collected between 03 and 05am showed the highest agreement with mean nighttime values of renal function. Since there is a good correlation and agreement between basic and extended urine collections to study the mechanisms underlying urine production, the choice of urine sampling method to evaluate urine production depends on the purpose. A nighttime-only urine sample collected between 03 and 05am may be the most practical approach. © 2017 Wiley Periodicals, Inc.

  11. A Preliminary Study on the Toxic Combustion Products Testing of Polymers Used in High-Pressure Oxygen Systems

    NASA Technical Reports Server (NTRS)

    Hshieh, Fu-Yu; Beeson, Harold D.

    2004-01-01

    One likely cause of polymer ignition in a high-pressure oxygen system is adiabatic-compression heating of polymers caused by pneumatic impact. Oxidative _ pyrolysis or combustion of polymers in a high-pressure oxygen system could generate toxic gases. This paper reports the preliminary results of toxic combustion product testing of selected polymers in a pneumatic-impact test system. Five polymers commonly used in high-pressure oxygen systems, Nylon 6/6, polychlorotrifluoroethylene (CTFE), polytetrafluoroethylene (PTFE), fluoroelastomer (Viton(TradeMark) A), and nitrile rubber (Buna N), were tested in a pneumatic-impact test system at 2500- or 3500-psia oxygen pressure. The polymers were ignited and burned, then combustion products were collected in a stainless-steel sample bottle and analyzed by GC/MS/IRD, GC/FID, and GC/Methanizer/FID. The results of adiabatic-compression tests show that combustion of hydrocarbon polymers, nitrogen-containing polymers, and halogenated polymers in high-pressure oxygen systems are relatively complete. Toxicity of the combustion product gas is presumably much lower than the combustion product gas generated from ambient-pressure oxygen (or air) environments. The NASA-Lewis equilibrium code was used to determine the composition of combustion product gas generated from a simulated, adiabatic-compression test of nine polymers. The results are presented and discussed.

  12. Basic Skills Applications in Occupational Investigation.

    ERIC Educational Resources Information Center

    Hendrix, Mary

    This guide contains 50 lesson plans for learning activities that incorporate basic skills into content areas of career education, mathematics, science, social studies, communications, and productive work habits. Each lesson consists of a purpose, basic skills applications, approximate time required, materials needed, things for the teacher to do…

  13. X-Ray Photoelectron Study of the Oxides Formed on Nickel Metal and Nickel-Chromium 20% Alloy Surfaces Under Reducing and Oxidizing Potentials in Basic, Neutral and Acidic Solutions

    NASA Astrophysics Data System (ADS)

    Payne, Brad P.; Keech, Peter G.; McIntyre, N. Stewart

    The corrosion products produced on polycrystalline Ni metal and Ni-Cr (20%) (NiCr) alloy surfaces exposed to aqueous environments chosen to emulate possible solution conditions in the steam generator (SG) tubing of pressurized water reactors (PWR) were studied using XPS. Additional measurements modelling the distribution of oxidized Ni and Cr species on select alloy specimens were carried out using ToF SIMS. Exposure of Ni metal and NiCr alloy samples to mildly oxidizing potentials in basic solutions resulted in the preferential growth of a β-Ni(OH)2 phase; driven by the dissolution of metallic Ni at both 25°C and 150°C. The presence of β-Ni(OH)2, Cr(OH)3 and small amounts of a Cr6+-containing oxide on NiCr specimens oxidized under mildly oxidizing conditions at 150°C in neutral solutions suggested that the dissolution of both metallic Ni and Cr followed by the back deposition of the corresponding corrosion products was responsible for oxide growth under these conditions. In acidic media oxide nucleation at 150°C under mildly oxidizing potentials was determined to occur via the dissolution of both Ni and Cr species on NiCr specimens as well. The increased stability of Ni2+ in acidic solution led to a limited precipitation of β-Ni(OH)2 resulting in the formation of very thin oxides containing higher levels of Cr(OH)3. Reactions on metallic Ni and NiCr surfaces under highly oxidizing potentials resulted in an increase in the NiO content of these films compared to similar exposures carried out at milder oxidation conditions attributed to accelerated dehydration of the β-Ni(OH)2 phase. In addition, an increase in the Cr(OH)3 contribution on the alloy surface oxidized at a more oxidative potential suggested a more rapid dissolution of Cr under these conditions; overall, uneven films were formed from these conditions. The composition of the corrosion product formed after an exposure to a highly oxidizing potential was found to be unchanged following a subsequent reaction of equivalent length at a much lower oxidizing potential in basic solution.

  14. Understanding the high pressure properties of molecular solids and molecular surfaces deposited on hetrogeneous substrates

    NASA Technical Reports Server (NTRS)

    Etters, R. D.

    1985-01-01

    Work directed toward understanding the high pressure properties of molecular solids and molecular surfaces deposited on hetrogeneous substrates is reported. The motivation, apart from expanding our basic knowledge about these systems, was to understand and predict the properties of new materials synthesized at high pressure, including pressure induced metallic and superconducting states. As a consequence, information about the states of matter of the Jovian planets and their satellites, which are natural high pressure laboratories was also provided. The work on molecular surfaces and finite two and three dimensional clusters of atoms and molecules was connected with the composition and behavior of planetary atmospheres and on the processes involved in forming surface layers, which is vital to the development of composite materials and microcircuitry.

  15. Two inviscid computational simulations of separated flow about airfoils

    NASA Technical Reports Server (NTRS)

    Barnwell, R. W.

    1976-01-01

    Two inviscid computational simulations of separated flow about airfoils are described. The basic computational method is the line relaxation finite-difference method. Viscous separation is approximated with inviscid free-streamline separation. The point of separation is specified, and the pressure in the separation region is calculated. In the first simulation, the empiricism of constant pressure in the separation region is employed. This empiricism is easier to implement with the present method than with singularity methods. In the second simulation, acoustic theory is used to determine the pressure in the separation region. The results of both simulations are compared with experiment.

  16. Effects of high combustion chamber pressure on rocket noise environment

    NASA Technical Reports Server (NTRS)

    Pao, S. P.

    1972-01-01

    The acoustical environment for a high combustion chamber pressure engine was examined in detail, using both conventional and advanced theoretical analysis. The influence of elevated chamber pressure on the rocket noise environment was established, based on increase in exit velocity and flame temperature, and changes in basic engine dimensions. Compared to large rocket engines, the overall sound power level is found to be 1.5 dB higher, if the thrust is the same. The peak Strouhal number shifted about one octave lower to a value near 0.01. Data on apparent sound source location and directivity patterns are also presented.

  17. Low pressure microenvironments: Methane production at 50 mbar and 100 mbar by methanogens

    NASA Astrophysics Data System (ADS)

    Mickol, Rebecca L.; Kral, Timothy A.

    2018-04-01

    Low pressure is often overlooked in terms of possible biocidal effects when considering a habitable environment on Mars. Few experiments have investigated the ability for microorganisms to actively grow under low pressure conditions, despite the atmosphere being a location on Earth where organisms could be exposed to these pressures. Three species of methanogens (Methanobacterium formicicum, Methanosarcina barkeri, Methanococcus maripaludis) were tested for their ability to actively grow (demonstrate an increase in methane production and optical density) within low-pressure microenvironments at 50 mbar or 100 mbar. M. formicicum was the only species to demonstrate both an increase in methane and an increase in optical density during the low-pressure exposure period for experiments conducted at 50 mbar and 100 mbar. In certain experiments, M. barkeri showed an increase in optical density during the low-pressure exposure period, likely due to the formation of multicellular aggregates, but minimal methane production (<1%). During incubation following exposure to low pressure, cultures of all species resumed methane production and increased in optical density. Thus, low pressure may not be a biocidal factor for certain methanogen species, with growth possible under low-pressure conditions. Results indicate that low pressure exposure may just be inhibitory during the exposure itself, and metabolism may resume following incubation under more ideal conditions. Further work is needed to address growth/survival under Mars surface pressures.

  18. Crew systems and architectural considerations for first lunar surface return missions

    NASA Astrophysics Data System (ADS)

    Winisdoerffer, F.; Ximenes, S.

    1992-08-01

    The design requirements for the habitability of the pressurized volumes of a typical first manned lander are presented. Attention is given to providing dual habitation/exploration services (EVA/IVA), supporting the separation of the surface/flight functions, allowing growth potential based on site characteristics, and in situ resources utilization. Lunar lander conceptual diagrams are provided for the basic system architecture, automatic cargo delivery, the piloted crew module, and the pressurized volumes.

  19. Basic Studies on High Pressure Air Plasmas

    DTIC Science & Technology

    2006-08-30

    which must be added a 1.5 month salary to A. Bugayev for assistance in laser and optic techniques. 2 Part II Technical report Plasma-induced phase shift...two-wavelength heterodyne interferometry applied to atmospheric pressure air plasma 11.1 .A. Plasma-induced phase shift - Electron density...a driver, since the error on the frequency leads to an error on the phase shift. (c) Optical elements Mirrors Protected mirrors must be used to stand

  20. Enhanced oil recovery using flash-driven steamflooding

    DOEpatents

    Roark, Steven D.

    1990-01-01

    The present invention is directed to a novel steamflooding process which utilizes three specific stages of steam injection for enhanced oil recovery. The three stages are as follows: As steam is being injected into an oil-bearing reservoir through an injection well, the production rate of a production well located at a distance from the injection well is gradually restricted to a point that the pressure in the reservoir increases at a predetermined rate to a predetermined maximum value. After the maximum pressure has been reached, the production rate is increased to a value such that the predetermined maximum pressure value is maintained. Production at maximum pressure is continued for a length of time that will be unique for each individual reservoir. In some cases, this step of the steamflooding process of the invention may be omitted entirely. In the third stage of the steamflooding process of the invention, production rates at the producing well are increased gradually to allow the pressure to decrease down from the maximum pressure value to the original pressure value at the producing well. The rate of pressure reduction will be unique for each reservoir. After completing stage three, the three stages can be repeated or the steamflood may be terminated as considered desirable.

  1. I. Synthesis, characterization, and base catalysis of novel zeolite supported super-basic materials II. Oxidative dehydrogenation of ethane over reduced heteropolyanion catalysts

    NASA Astrophysics Data System (ADS)

    Galownia, Jonathan M.

    This thesis is composed of two separate and unrelated projects. The first part of this thesis outlines an investigation into the synthesis and characterization of a novel zeolite supported super-base capable of carbon-carbon olefin addition to alkyl aromatics. A zeolite supported basic material capable of such reactions would benefit many fine chemical syntheses, as well as vastly improve the economics associated with production of the high performance thermoplastic polyester polyethylene naphthalate. The thermal decomposition of alkali---metal azides impregnated in zeolite X is investigated as a novel route to the synthesis of a zeolite supported super-base. Impregnation of the alkali---metal azide precursor is shown to result in azide species occluded within the pores of the zeolite support by using high speed, solid-state 23Na MAS and 2D MQMAS NMR, FTIR, and TGA characterization methods. Addition of alkali---metal azides to the zeolite results in redistribution of the extra-lattice cations in the zeolite framework. Thermal decomposition of impregnated azide species produces further cation redistribution, but no neutral metallic clusters are detected by high speed, solid-state 23Na MAS NMR following thermal activation of the materials. Instead, it is possible that inactive ionic clusters are formed. The thermally activated materials do not promote base catalysis for the isomerization of 1-butene, the ethylation of toluene and o-xylene, and the alkenylation of o-xylene with 1,3-butadiene to produce 5-ortho-tolyl-pent-2-ene (5-OTP). The lack of catalytic activity in the materials is attributed to failure of the materials to form neutral metallic clusters during thermal treatment, possibly due to preferential formation of NMR silent ionic clusters. The formation of neutral metallic clusters is found to be insensitive to synthesis technique and activation procedure. It is concluded that the impregnation of alkali---metal azides in zeolite X does not provide a reliable precursor for the formation of zeolite supported super-basic materials. The second part of this thesis describes the oxidative dehydrogenation of ethane over partially reduced heteropolyanions. Niobium and pyridine exchanged salts of phosphomolybdic (NbPMo12Pyr) and phosphovanadomolybdic (NbPMo11VPyr) acids are investigated as catalyst precursors to prepare materials for catalyzing the oxidative dehydrogenation of ethane to ethylene and acetic acid at atmospheric pressure. The effects of feed composition, steam flow, temperature, and precursor composition on catalytic activity and selectivity are presented for both ethane and ethylene oxidation. Production of ethylene and acetic acid from ethane using the catalytic materials exceeds that reported in the literature for Mo-V-Nb-Ox systems under atmospheric or elevated pressure. Production of acetic acid from ethylene is also greater than that observed for Mo-V-Nb-Ox systems. Addition of vanadium reduces catalytic activity and selectivity to both ethylene and acetic acid while niobium is essential for the formation of acetic acid from ethane. Other metals such as antimony, iron, and gallium do not provide the same beneficial effect as niobium. Molybdenum in close proximity to niobium is the active site for ethane activation while niobium is directly involved in the transformation of ethylene to acetic acid. A balance of niobium and protonated pyridine is required to produce an active catalyst. Water is found to aid in desorption of acetic acid, thereby limiting deep oxidation to carbon oxides. A reaction scheme is proposed for the production of acetic acid from ethane over the catalytic materials.

  2. Stability and oxidation products of hydrolysable tannins in basic conditions detected by HPLC/DAD-ESI/QTOF/MS.

    PubMed

    Tuominen, Anu; Sundman, Terhi

    2013-01-01

    Hydrolysable tannins occur in plants that are used for food or medicine by humans or herbivores. Basic conditions can alter the structures of tannins, that is, the oxidation of phenolic groups can lead to the formation of toxic quinones. Previously, these labile quinones and other oxidation products have been studied with colorimetric or electron paramagnetic resonance methods, which give limited information about products. To study the stability and oxidation products of hydrolysable tannins in basic conditions using HPLC with a diode-array detector (DAD) combined with electrospray ionisation (ESI) and quadrupole time-of-flight (QTOF) MS. Three galloyl glucoses, four galloyl derivatives with different polyols and three ellagitannins were purified from plants. The incubation reactions of tannins were monitored by HPLC/DAD at five pH values and in reduced oxygen conditions. Reaction products were identified based on UV spectra and mass spectral fragmentation obtained with the high-resolution HPLC/DAD-ESI/QTOF/MS. The use of a base-resistant HPLC column enabled injections without the sample pre-treatment and thus detection of short-lived products. Hydrolysable tannins were unstable in basic conditions and half-lives were mostly less than 10 min at pH 10. Degradation rates were faster at pH 11 but slower at milder pH. The HPLC analyses revealed that various products were formed and identified to be the result of hydrolysis, deprotonation and oxidation. Interestingly, the main hydrolysis product was ellagic acid; it was also formed from galloyl glucoses that do not contain oxidatively coupled galloyl groups in their initial structures. HPLD/DAD-ESI/QTOF/MS was an efficient method for the identification of polyphenol oxidation products and showed how different pH conditions determine the fate of hydrolysable tannins. Copyright © 2013 John Wiley & Sons, Ltd.

  3. Ability of the new AT1 receptor blocker azilsartan to block angiotensin II-induced AT1 receptor activation after wash-out.

    PubMed

    Miura, Shin-ichiro; Matsuo, Yoshino; Nakayama, Asuka; Tomita, Sayo; Suematsu, Yasunori; Saku, Keijiro

    2014-03-01

    The recently approved angiotensin II (Ang II) type 1 (AT1) receptor blocker (ARB) azilsartan strongly reduces blood pressure (BP) in patients with hypertension. We previously reported that azilsartan showed unique binding behavior to the AT1 receptor because of its 5-oxo-1,2,4-oxadiazole moiety. However, the ability of azilsartan to block Ang II-dependent AT1 receptor activation is not yet clear. Azilsartan and a derivative of azilsartan (azilsartan-7H) that lacks a carboxyl group at the benzimidazole ring were used. Ang II-induced inositol phosphate (IP) production and extracellular signal-regulated kinase (ERK) activation were analyzed in a cell-based wash-out assay. Azilsartan, but not azilsartan-7H, completely blocked Ang II-induced IP production and ERK activation. Our previous report demonstrated that azilsartan mainly interacts with Tyr(113), Lys(199), and Gln(257) in the AT1 receptor. The interactions between azilsartan and Tyr(113) and Gln(257), but not Lys(199), were critical for blocking Ang II-induced IP production and ERK activation after wash-out. Although our findings regarding the molecule-specific effects of azilsartan are based on basic research, they may lead to an exciting insight into the mechanism of azilsartan.

  4. Pitting Behavior of L415 Pipeline Steel in Simulated Leaching Liquid Environment

    NASA Astrophysics Data System (ADS)

    Wan, H. X.; Yang, X. J.; Liu, Z. Y.; Song, D. D.; Du, C. W.; Li, X. G.

    2017-02-01

    The corrosion behavior and laws of the west-east gas pressure pipeline of L415 steel were studied in simulated leaching liquid. The failure of the L415 steel during the pressure testing process was investigated using electrochemical polarization, electrochemical impedance spectroscopy, and immersion test. The corrosion rate of the L415 steel increased with ion concentration in the leaching liquid. This rate reached about 0.8 mm a-1 and belonged to the severe corrosion grade. Pitting corrosion was observed in various simulated solutions with different aggressive species concentrations. The original ion concentration in the leaching liquid (1×) is the key factor influencing pitting initiation and development. Pitting showed easy nucleation, and its growth rate was relatively slow, in the basic simulating solution of the leach liquid (i.e., the ion content is compactable to the real condition in the rust on the inner steel pipe surface). Pitting was also highly sensitive and easily grew in the solution with doubled ion concentration in the basic simulating solution (2×). A uniform corrosion, instead of pitting, mainly occurred when the ion concentration was up to 10× of the basic solution.

  5. Blood-Pressure Measuring System Gives Accurate Graphic Output

    NASA Technical Reports Server (NTRS)

    1965-01-01

    The problem: To develop an instrument that will provide an external (indirect) measurement of arterial blood pressure in the form of an easily interpreted graphic trace that can be correlated with standard clinical blood-pressure measurements. From sphygmograms produced by conventional sphygmographs, it is very difficult to differentiate the systolic and diastolic blood-pressure pulses and to correlate these indices with the standard clinical values. It is nearly impossible to determine these indices when the subject is under physical or emotional stress. The solution: An electronic blood-pressure system, basically similar to conventional ausculatory sphygmomanometers, employing a standard occluding cuff, a gas-pressure source, and a gas-pressure regulator and valve. An electrical output transducer senses cuff pressure, and a microphone positioned on the brachial artery under the occluding cuff monitors the Korotkoff sounds from this artery. The output signals present the conventional systolic and diastolic indices in a clear, graphical display. The complete system also includes an electronic timer and cycle-control circuit.

  6. Basic Principles of Animal Science. Reprinted.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    The reference book is designed to fulfill the need for organized subject matter dealing with basic principles of animal science to be incorporated into the high school agriculture curriculum. The material presented is scientific knowledge basic to livestock production. Five units contain specific information on the following topics: anatomy and…

  7. Rethinking the Formula: Suggestions for Improving Basic Course Texts.

    ERIC Educational Resources Information Center

    Robie, Harry

    There are three arguments against the usefulness of present basic course textbooks in speech communication. First, there are certain inherent forces that will always drive textbook publishers toward the production of textbooks unsuitable for the basic course: "mentioning" (mentioning every principle ever heard of by potential users of…

  8. Basic Language Skills and Young Children's Understanding of Causal Connections during Storytelling

    ERIC Educational Resources Information Center

    Brown, Danielle D.; Lile, Jacquelyn; Burns, Barbara M.

    2011-01-01

    The current study examined the role of basic language skills for individual differences in preschoolers' understanding of causal connections. Assessments of basic language skills, expressive vocabulary, phonological processing, and receptive language comprehension were examined in relation to the production of causal connections in a storytelling…

  9. Hydrogen production by reforming of liquid hydrocarbons in a membrane reactor for portable power generation-Experimental studies

    NASA Astrophysics Data System (ADS)

    Damle, Ashok S.

    One of the most promising technologies for lightweight, compact, portable power generation is proton exchange membrane (PEM) fuel cells. PEM fuel cells, however, require a source of pure hydrogen. Steam reforming of hydrocarbons in an integrated membrane reactor has potential to provide pure hydrogen in a compact system. Continuous separation of product hydrogen from the reforming gas mixture is expected to increase the yield of hydrogen significantly as predicted by model simulations. In the laboratory-scale experimental studies reported here steam reforming of liquid hydrocarbon fuels, butane, methanol and Clearlite ® was conducted to produce pure hydrogen in a single step membrane reformer using commercially available Pd-Ag foil membranes and reforming/WGS catalysts. All of the experimental results demonstrated increase in hydrocarbon conversion due to hydrogen separation when compared with the hydrocarbon conversion without any hydrogen separation. Increase in hydrogen recovery was also shown to result in corresponding increase in hydrocarbon conversion in these studies demonstrating the basic concept. The experiments also provided insight into the effect of individual variables such as pressure, temperature, gas space velocity, and steam to carbon ratio. Steam reforming of butane was found to be limited by reaction kinetics for the experimental conditions used: catalysts used, average gas space velocity, and the reactor characteristics of surface area to volume ratio. Steam reforming of methanol in the presence of only WGS catalyst on the other hand indicated that the membrane reactor performance was limited by membrane permeation, especially at lower temperatures and lower feed pressures due to slower reconstitution of CO and H 2 into methane thus maintaining high hydrogen partial pressures in the reacting gas mixture. The limited amount of data collected with steam reforming of Clearlite ® indicated very good match between theoretical predictions and experimental results indicating that the underlying assumption of the simple model of conversion of hydrocarbons to CO and H 2 followed by equilibrium reconstitution to methane appears to be reasonable one.

  10. Production and Testing of Transgenic Cotton that Expresses Transcription Factors for Enhanced Seed and Fiber Traits and Productivity Under Drought Stress

    USDA-ARS?s Scientific Manuscript database

    Abscisic acid (ABA) is a plant hormone involved in abiotic and biotic stress adaptation and seed development. We have previously shown that Basic3 (B3) domain and basic leucine zipper (b-ZIP) transcription factors from the model plant species maize and Arabidopsis thaliana can transactivate monocot...

  11. Loss of interface pressure in various compression bandage systems over seven days.

    PubMed

    Protz, Kerstin; Heyer, Kristina; Verheyen-Cronau, Ida; Augustin, Matthias

    2014-01-01

    Manufacturers' instructions of multi-component compression bandage systems inform that these products can remain up to 7 days during the therapy of venous leg ulcer. This implies that the pressure needed will be sustained during this time. The present research investigated the persistence of pressure of compression systems over 7 days. All 6 compression systems available in Germany at the time of the trial were tested on 35 volunteering persons without signs of venous leg disease. Bandaging with short-stretch bandages was included for comparison. Pressure was measured by using PicoPress®. Initially, all products showed sufficient resting pressure of 40 mm Hg checked with a pressure monitor, except for one system in which the pressure fell by at least 23.8%, the maximum being 47.5% over a period of 7 days. The currently available compression systems are not fit to keep the required pressure. Optimized products need to be developed.

  12. Numerical Study of Pressure Influence on Methane-Oxygen Laminar Counterflow Diffusion Flames

    NASA Astrophysics Data System (ADS)

    Iino, Kimio; Akamatsu, Fumiteru; Katsuki, Masashi

    We carried out numerical studies on methane/oxygen diffusion flames of counter-flow configuration to elucidate the influence of pressure on flame structure, heat release rate and reaction mechanisms. The chemistry in gas-phase was based on GRI-Mech 3.0 database. The thickness of diffusion flame became thinner with increasing strain rate a , with its characteristic flame thickness varying inversely with √a, especially its relation became significant with increasing pressure. Flame temperature increased with increasing pressure. Enhanced H2O production reactions, especially chain terminal reactions for H2O production, were found to be important in determining the flame temperature at high pressures. The small reduction in the flame temperature with increasing strain rate at high pressures, compared to the atmospheric pressure, is caused by the capacitor effect of product dissociation. From QRPDs, the third body dependent reactions were enhanced in high pressure conditions, hence C2 pathway was enhanced.

  13. Use of Positive Pressures to Establish Vulnerability Curves 1

    PubMed Central

    Cochard, Hervé; Cruiziat, Pierre; Tyree, Melvin T.

    1992-01-01

    Loss of hydraulic conductivity occurs in stems when the water in xylem conduits is subjected to sufficiently negative pressure. According to the air-seeding hypothesis, this loss of conductivity occurs when air bubbles are sucked into water-filled conduits through micropores adjacent to air spaces in the stem. Results in this study showed that loss of hydraulic conductivity occurred in stem segments pressurized in a pressure chamber while the xylem water was under positive pressure. Vulnerability curves can be defined as a plot of percentage loss of hydraulic conductivity versus the pressure difference between xylem water and the outside air inducing the loss of conductivity. Vulnerability curves were similar whether loss of conductivity was induced by lowering the xylem water pressure or by raising the external air pressure. These results are consistent with the air-seeding hypothesis of how embolisms are nucleated, but not with the nucleation of embolisms at hydrophobic cracks because the latter requires negative xylem water pressure. The results also call into question some basic underlying assumptions used in the determination of components of tissue water potential using “pressure-volume” analysis. PMID:16652947

  14. Liquid sinusoidal pressure measurement by laser interferometry based on the refractive index of water.

    PubMed

    Yang, Jun; Fan, Shangchun; Li, Cheng; Guo, Zhanshe; Li, Bo; Shi, Bo

    2016-12-01

    A new method with laser interferometry is used to enhance the traceability for sinusoidal pressure calibration in water. The laser vibrometer measures the dynamic pressure based on the acousto-optic effect. The relation of the refractive index of water and the optical path length with the pressure's change is built based on the Lorentz-Lorenz equation, and the conversion coefficients are tested by static calibration in situ. A device with a piezoelectric transducer and resonant pressure pipe with water is set up to generate sinusoidal pressure up to 20 kHz. With the conversion coefficients, the reference sinusoidal pressure is measured by the laser interferometer for pressure sensors' dynamic calibration. The experiment results show that under 10 kHz, the measurement results between the laser vibrometer and a piezoelectric sensor are in basic agreement and indicate that this new method and its measurement system are feasible in sinusoidal pressure calibration. Some disturbing components including small amplitude, temperature change, pressure maldistribution, and glass windows' vibration are also analyzed, especially for the dynamic calibrations above 10 kHz.

  15. Ultrafast secondary emission X-ray imaging detectors: A possible application to TRD

    NASA Astrophysics Data System (ADS)

    Akkerman, A.; Breskin, A.; Chechik, R.; Elkind, V.; Gibrekhterman, A.; Majewski, S.

    1992-05-01

    Fist high accuracy, X-ray imaging at high photon flux can be achieved when coupling thin solid convertors to gaseous electron multipliers, operating at low gas pressures. Secondary electrons emitted from the convertor foil are multiplied in several successive amplification elements. The obvious advantages of solid X-ray convertors, as compared to gaseous conversion, are the production of parallax-free images and the fast (subnanosecond) response. These X-ray detectors have many potential applications in basic and applied research. Of particular interest is the possibility of an efficient and ultrafast high resolution imaging of transition radiation (TR), with a reduced d E/d x background. We present experimental results on the operation of secondary emission X-ray (SEX) detectors, their detection efficiency, localization and time resolution. The experimental work is accompanied by mathematical modelling and computer simulation of transition radiation detectors (TRDs) based on CsI TR convertors.

  16. Refolding of denatured/reduced lysozyme at high concentration with diafiltration.

    PubMed

    Yoshii, H; Furuta, T; Yonehara, T; Ito, D; Linko, Y Y; Linko, P

    2000-06-01

    Refolding of reduced and denatured protein in vitro has been an important issue for both basic research and applied biotechnology. Refolding at low protein concentration requires large volumes of refolding buffer. Among various refolding methods, diafiltration is very useful to control the denaturant and red/ox reagents in a refolding solution. We constructed a refolding procedure of high lysozyme concentration (0.5-10 mg/ml) based on the linear reduction of the urea concentration during diafiltration under oxygen pressure. When the urea concentration in the refolding vessel was decreased from 4 M with a rate of 0.167 M/h, the refolding yields were 85% and 63% at protein concentrations, 5 mg/ml and 10 mg/ml, respectively, after 11 h. This method gave a high productivity of 40.1,microM/h of the refolding lysozyme. The change in refolding yields during the diafiltration could be simulated using the model of Hevehan and Clark.

  17. Continuous metabolic and cardiovascular measurements on a monkey subject during a simulated 6-day Spacelab mission

    NASA Technical Reports Server (NTRS)

    Pace, N.; Rahlmann, D. F.; Mains, R. C.; Kodama, A. M.; Mccutcheon, E. P.

    1979-01-01

    A 10-kg male pig-tailed monkey (Macaca nemestrina) was selected as an optimal species for spaceflight studies on weightlessness. Three days before the simulated launch, the animal was placed in a fiberglass pod system to provide continuous measurement of respiratory gas exchange. Attention is given to examining the effects of weightlessness on several basic parameters of metabolic and cardiovascular function in an adult nonhuman primate. The 10.7-day total simulated-experiment period consisted of preflight 2.6 days, inflight 6.3 days, and postflight 1.8 days. Statistically significant diurnal variation was noted in oxygen consumption and CO2 production rates, body temperature and HR, but not in respiratory quotient or blood pressure. The high quality of the continuous data obtained demonstrates the feasibility of performing sound physiological experimentation on nonhuman primates in the Spacelab environment.

  18. Membrane processing technology in the food industry: food processing, wastewater treatment, and effects on physical, microbiological, organoleptic, and nutritional properties of foods.

    PubMed

    Kotsanopoulos, Konstantinos V; Arvanitoyannis, Ioannis S

    2015-01-01

    Membrane processing technology (MPT) is increasingly used nowadays in a wide range of applications (demineralization, desalination, stabilization, separation, deacidification, reduction of microbial load, purification, etc.) in food industries. The most frequently applied techniques are electrodialysis (ED), reverse osmosis (RO), nanofiltration (NF), ultrafiltration (UF), and microfiltration (MF). Several membrane characteristics, such as pore size, flow properties, and the applied hydraulic pressure mainly determine membranes' potential uses. In this review paper the basic membrane techniques, their potential applications in a large number of fields and products towards the food industry, the main advantages and disadvantages of these methods, fouling phenomena as well as their effects on the organoleptic, qualitative, and nutritional value of foods are synoptically described. Some representative examples of traditional and modern membrane applications both in tabular and figural form are also provided.

  19. The EPMI Malay Basin petroleum geology database: Design philosophy and keys to success

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Low, H.E.; Creaney, S.; Fairchild, L.H.

    1994-07-01

    Esso Production Malaysia Inc. (EPMI) developed and populated a database containing information collected in the areas of basic well data: stratigraphy, lithology, facies; pressure, temperature, column/contacts; geochemistry, shows and stains, migration, fluid properties; maturation; seal; structure. Paradox was used as the database engine and query language, with links to ZYCOR ZMAP+ for mapping and SAS for data analysis. Paradox has a query language that is simple enough for users. The ability to link to good analytical packages was deemed more important than having the capability in the package. Important elements of design philosophy were included: (1) information on data qualitymore » had to be rigorously recorded; (2) raw and interpreted data were kept separate and clearly identified; (3) correlations between rock and chronostratigraphic surfaces were recorded; and (4) queries across technical boundaries had to be seamless.« less

  20. A new approach to promoting sluggish Diels-Alder reactions: dihapto-coordination of the diene.

    PubMed

    Liu, Weijun; You, Fei; Mocella, Christopher J; Harman, W Dean

    2006-02-08

    The cycloaddition between 1,3-cyclohexadiene and various enones and enals (methyl vinyl ketone, ethyl vinyl ketone, methacrolien) is accomplished at room temperature in yields ranging from 51 to 68% without the use of Lewis acids, high pressures, or microwave reactors. This normally sluggish cyclization is accomplished by precoordination of the diene to a pi-basic molybdenum complex. The eta2-bound metal is thought to promote a Michael reaction between the uncoordinated portion of the diene and the enone, and the resulting enolate then closes to form the cycloalkene product. The organic cycloadduct is removed by oxidation with air or with silver triflate in nearly quantitative yield. For more sterically hindered enones (e.g., mesityl oxide) and for methyl acrylate, the desired outcome requires the use of BF3.OEt2, and yields are significantly lower (15-35%)

  1. Physical properties of organic fullerene cocrystals

    NASA Astrophysics Data System (ADS)

    Macovez, Roberto

    2017-12-01

    The basic facts and fundamental properties of binary fullerene cocrystals are reviewed, focusing especially on solvates and salts of Buckminsterfullerene (C60), and hydrates of hydrophilic C60 derivatives. The examined properties include the lattice structure and the presence of orientational disorder and/or rotational dynamics (of both fullerenes and cocrystallizing moieties), thermodynamic properties such as decomposition enthalpies, and charge transport properties. Both thermodynamic properties and molecular orientational disorder shed light on the extent of intermolecular interactions in these binary solid-state systems. Comparison is carried out also with pristine fullerite and with the solid phases of functionalized C60. Interesting experimental findings on binary fullerene cocrystals include the simultaneous occurrence of rotations of both constituent molecular species, crystal morphologies reminiscent of quasi-crystalline behaviour, the observation of proton conduction in hydrate solids of hydrophilic fullerene derivatives, and the production of super-hard carbon materials by application of high pressures on solvated fullerene crystals.

  2. Architects of the Future--Managing Change.

    ERIC Educational Resources Information Center

    Conner, Daryl; Hughes, K. Scott

    1988-01-01

    Some of the basic principles involved in successfully managing organizational change in higher education are described. Change factors include: human resources demands, cost containment pressure, global competitive economic society, increasing technological innovation, and increasing capital investment requirements. (MLW)

  3. Microsoft excel spreadsheets for calculation of P-V-T relations and thermodynamic properties from equations of state of MgO, diamond and nine metals as pressure markers in high-pressure and high-temperature experiments

    NASA Astrophysics Data System (ADS)

    Sokolova, Tatiana S.; Dorogokupets, Peter I.; Dymshits, Anna M.; Danilov, Boris S.; Litasov, Konstantin D.

    2016-09-01

    We present Microsoft Excel spreadsheets for calculation of thermodynamic functions and P-V-T properties of MgO, diamond and 9 metals, Al, Cu, Ag, Au, Pt, Nb, Ta, Mo, and W, depending on temperature and volume or temperature and pressure. The spreadsheets include the most common pressure markers used in in situ experiments with diamond anvil cell and multianvil techniques. The calculations are based on the equation of state formalism via the Helmholtz free energy. The program was developed using Visual Basic for Applications in Microsoft Excel and is a time-efficient tool to evaluate volume, pressure and other thermodynamic functions using T-P and T-V data only as input parameters. This application is aimed to solve practical issues of high pressure experiments in geosciences and mineral physics.

  4. Liquid Propulsion: Propellant Feed System Design. Chapter 2.3.11

    NASA Technical Reports Server (NTRS)

    Cannon, James L.

    2010-01-01

    The propellant feed system of a liquid rocket engine determines how the propellants are delivered from the tanks to the thrust chamber. They are generally classified as either pressure fed or pump fed. The pressure-fed system is simple and relies on tank pressures to feed the propellants into the thrust chamber. This type of system is typically used for space propulsion applications and auxiliary propulsion applications requiring low system pressures and small quantities of propellants. In contrast, the pump-fed system is used for high pressure, high performance applications. The selection of one propellant feed system over another is determined based on design trade studies at both the engine and vehicle levels. This chapter first provides a brief overview of the basic configurations of pressure-fed systems. Pump-fed systems are then discussed with greater detail given to the turbomachinery design. Selected design requirements and configurations are provided.

  5. Fractional watt Vuillemier cryogenic refrigerator program engineering notebook. Volume 1: Thermal analysis

    NASA Technical Reports Server (NTRS)

    Miller, W. S.

    1974-01-01

    The cryogenic refrigerator thermal design calculations establish design approach and basic sizing of the machine's elements. After the basic design is defined, effort concentrates on matching the thermodynamic design with that of the heat transfer devices (heat exchangers and regenerators). Typically, the heat transfer device configurations and volumes are adjusted to improve their heat transfer and pressure drop characteristics. These adjustments imply that changes be made to the active displaced volumes, compensating for the influence of the heat transfer devices on the thermodynamic processes of the working fluid. Then, once the active volumes are changed, the heat transfer devices require adjustment to account for the variations in flows, pressure levels, and heat loads. This iterative process is continued until the thermodynamic cycle parameters match the design of the heat transfer devices. By examing several matched designs, a near-optimum refrigerator is selected.

  6. A Thermodynamically General Theory for Convective Circulations and Vortices

    NASA Astrophysics Data System (ADS)

    Renno, N. O.

    2007-12-01

    Convective circulations and vortices are common features of atmospheres that absorb low-entropy-energy at higher temperatures than they reject high-entropy-energy to space. These circulations range from small to planetary-scale and play an important role in the vertical transport of heat, momentum, and tracer species. Thus, the development of theoretical models for convective phenomena is important to our understanding of many basic features of planetary atmospheres. A thermodynamically general theory for convective circulations and vortices is proposed. The theory includes irreversible processes and quantifies the pressure drop between the environment and any point in a convective updraft. The article's main result is that the proposed theory provides an expression for the pressure drop along streamlines or streamtubes that is a generalization of Bernoulli's equation to convective circulations. We speculate that the proposed theory not only explains the intensity, but also shed light on other basic features of convective circulations and vortices.

  7. Preliminary study of effects of winglets on wing flutter

    NASA Technical Reports Server (NTRS)

    Doggett, R. V., Jr.; Farmer, M. G.

    1976-01-01

    Some experimental flutter results are presented over a Mach number range from about 0.70 to 0.95 for a simple, swept, tapered, flat-plate wing model having a planform representative of subsonic transport airplanes and for the same wing model equipped with two different upper surface winglets. Both winglets had the same planform and area (about 2 percent of the basic-wing area); however, one weighed about 0.3 percent of the basic-wing weight, and the other weighed about 1.8 percent of the wing weight. The addition of the lighter winglet reduced the wing-flutter dynamic pressure by about 3 percent; the heavier winglet reduced the wing-flutter dynamic pressure by about 12 percent. The experimental flutter results are compared at a Mach number of 0.80 with analytical flutter results obtained by using doublet-lattice and lifting-surface (kernel-function) unsteady aerodynamic theories.

  8. Pressure Contact Sounding Data for NASA's Atmospheric Variability Experiment (AVE 3)

    NASA Technical Reports Server (NTRS)

    Fuelberg, H. E.; Hill, C. K.; Turner, R. E.; Long, K. E.

    1975-01-01

    The basic rawinsonde data are described at each pressure contact from the surface to sounding termination for the 41 stations participating in the AVE III measurement program that began at 0000 GMT on February 6 and ended at 1200 GMT on February 7, 1975. Soundings were taken at 3-hour intervals during a large period of the experiment from most stations within the United States east of about 105 degrees west longitude. Methods of data processing, change in reduction scheme since the AVE II pilot experiment, and data accuracy are briefly discussed. An example of contact data is presented, and microfiche cards of all the contact data are included in the appendix. The AVE III project was conducted to better understand and establish the extent of applications for meteorological satellite sensor data through correlative ground truth experiments and to provide basic experimental data for use in studies of atmospheric scales of-motion interrelationships.

  9. Analysis of the induction of the myelin basic protein binding to the plasma membrane phospholipid monolayer

    NASA Astrophysics Data System (ADS)

    Zhang, Lei; Hao, Changchun; Feng, Ying; Gao, Feng; Lu, Xiaolong; Li, Junhua; Sun, Runguang

    2016-09-01

    Myelin basic protein (MBP) is an essential structure involved in the generation of central nervous system (CNS) myelin. Myelin shape has been described as liquid crystal structure of biological membrane. The interactions of MBP with monolayers of different lipid compositions are responsible for the multi-lamellar structure and stability of myelin. In this paper, we have designed MBP-incorporated model lipid monolayers and studied the phase behavior of MBP adsorbed on the plasma membrane at the air/water interface by thermodynamic method and atomic force microscopy (AFM). By analyzing the pressure-area (π-A) and pressure-time (π-T) isotherms, univariate linear regression equation was obtained. In addition, the elastic modulus, surface pressure increase, maximal insertion pressure, and synergy factor of monolayers were detected. These parameters can be used to modulate the monolayers binding of protein, and the results show that MBP has the strongest affinity for 1,2-dipalmitoyl-sn-glycero-3- phosphoserine (DPPS) monolayer, followed by DPPC/DPPS mixed and 1,2-dipalmitoyl-sn-glycero-3-phospho-choline (DPPC) monolayers via electrostatic and hydrophobic interactions. AFM images of DPPS and DPPC/DPPS mixed monolayers in the presence of MBP (5 nM) show a phase separation texture at the surface pressure of 20 mN/m and the incorporation of MBP put into the DPPC monolayers has exerted a significant effect on the domain structure. MBP is not an integral membrane protein but, due to its positive charge, interacts with the lipid head groups and stabilizes the membranes. The interaction between MBP and phospholipid membrane to determine the nervous system of the disease has a good biophysical significance and medical value. Project supported by the National Natural Science Foundation of China (Grant Nos. 21402114 and 11544009), the Natural Science Basic Research Plan in Shaanxi Province of China (Grant No. 2016JM2010), the Fundamental Research Funds for the Central Universities of China (Grant No. GK201604004), and the National University Science and Technology Innovation Project of China (Grant Nos. 201610718014 and cx16018).

  10. New calibration method for I-scan sensors to enable the precise measurement of pressures delivered by 'pressure garments'.

    PubMed

    Macintyre, Lisa

    2011-11-01

    Accurate measurement of the pressure delivered by medical compression products is highly desirable both in monitoring treatment and in developing new pressure inducing garments or products. There are several complications in measuring pressure at the garment/body interface and at present no ideal pressure measurement tool exists for this purpose. This paper summarises a thorough evaluation of the accuracy and reproducibility of measurements taken following both of Tekscan Inc.'s recommended calibration procedures for I-scan sensors; and presents an improved method for calibrating and using I-scan pressure sensors. The proposed calibration method enables accurate (±2.1 mmHg) measurement of pressures delivered by pressure garments to body parts with a circumference ≥30 cm. This method is too cumbersome for routine clinical use but is very useful, accurate and reproducible for product development or clinical evaluation purposes. Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

  11. Environmental risks of the gas hydrate field development in the Eastern Nankai Trough

    NASA Astrophysics Data System (ADS)

    Yamamoto, K.; Nagakubo, S.

    2009-12-01

    To establish any kinds of new energy resources, environmental impacts of the technology should be well understood before full industrial implementation. Methane hydrate (MH), a relatively clean fossil energy with low CO2 and no SOx emission, is not an exception. Because methane gas itself has strong greenhouse gas effect, and methane hydrate is not stable under the atmospheric pressure and room temperature, public image of MH field development is very risky game and potentially disastrous to the global climate. However, the real physics of the MH bearing sediments is far different from such images. MH21 Research Consortium in Japan has studied about the resource assessment and production techniques to develop MH since 2001. As the results, we found several gas hydrate concentrated zones with pore filling type hydrate in sandy layers of turbidite sediment in the Eastern Nankai Trough area off coasts of the Central Japan. The depressurization technique, in the other word, in-situ MH dissociation by water production and natural heat supply from surrounding formation, will be used as the basic method to produce methane gas from MH. Under the conditions, we have evaluated realistic environmental risk of the MH production. Because the most MH found in the Eastern Nankai Trough are composed of biogenic and almost pure methane, there is no concern of sea water contamination by oil releases that is the most common environmental disaster caused by misconducts of the oil industry. Also MH reservoirs there are not pressurized, and blowout of wells during drilling is very unlikely. Endothermic MH dissociation process decreases formation temperature with depressurization, and give negative feedback, then, there is no chance of chain reaction. Heat supply from surrounding formations is necessary for continuous dissociation, but heat transfer in the formations is relatively slow, and the dissociation rate is limited. Once the operation to pump water in boreholes for depressurization is stopped, or some troubles break surface facilities, pressure recovers to the original condition, but formation temperature is kept low by inflow of cold sea water. Therefore, the gas release risk of the offshore MH field is lower than conventional oil and gas. There can be a slight chance to release gas to seafloor after the production along with pressure recovery though natural and man-made pathways such as poorly abandoned wells, reactivated fractures or faults, etc. Even in the case, most of the discharged gas will be dissolved in to seawater, and almost no chance to discharge it into atmosphere. Another possible scenario is surface instability caused by weakened formation due to MH dissociation. To mitigate the risk to avoid catastrophic phenomena, site selection is the key. During the offshore production tests planned in 2012 and 2014, MH21 will conduct modelling, monitoring and verification program to quantify the real environmental risks of the MH field development.

  12. Analysing and modelling the growth behaviour of Listeria monocytogenes on RTE cooked meat products after a high pressure treatment at 400 MPa.

    PubMed

    Hereu, A; Dalgaard, P; Garriga, M; Aymerich, T; Bover-Cid, S

    2014-09-01

    Various predictive models are available for high pressure inactivation of Listeria monocytogenes in food, but currently available models do not consider the growth kinetics of surviving cells during the subsequent storage of products. Therefore, we characterised the growth of L. monocytogenes in sliced cooked meat products after a pressurization treatment. Two inoculum levels (10(7) or 10(4) CFU/g) and two physiological states before pressurization (freeze-stressed or cold-adapted) were evaluated. Samples of cooked ham and mortadella were inoculated, high pressure processed (400 MPa, 5 min) and subsequently stored at 4, 8 and 12 °C. The Logistic model with delay was used to estimate lag phase (λ) and maximum specific growth rate (μmax) values from the obtained growth curves. The effect of storage temperature on μmax and λ was modelled using the Ratkowsky square root model and the relative lag time (RLT) concept. Compared with cold-adapted cells the freeze-stressed cells were more pressure-resistant and showed a much longer lag phase during growth after the pressure treatment. Interestingly, for high-pressure inactivation and subsequent growth, the time to achieve a concentration of L. monocytogenes 100-fold (2-log) higher than the cell concentration prior to the pressure treatment was similar for the two studied physiological states of the inoculum. Two secondary models were necessary to describe the different growth behaviour of L. monocytogenes on ready-to-eat cooked ham (lean product) and mortadella (fatty product). This supported the need of a product-oriented approach to assess growth after high pressure processing. The performance of the developed predictive models for the growth of L. monocytogenes in high-pressure processed cooked ham and mortadella was evaluated by comparison with available data from the literature and by using the Acceptable Simulation Zone approach. Overall, 91% of the relative errors fell into the Acceptable Simulation Zone. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Pressure Control In A Tyre Of Moving Vehicle

    NASA Astrophysics Data System (ADS)

    Gawande, Kshitij P.; Jawanjal, Vaishakh A.

    2012-08-01

    We always try to make everything perfect around us and there is major problem still remaining in our automobiles, a puncture in a tire while running. We have developed tubeless tires but thatís not a perfect solution, so there is a serious need of improvement in this area. In this paper the compressed air is used to maintain the pressure in the tire using pneumatic pipes. This is a very basic concept which uses compressor power to maintain the pressure of a tire, while running using pressure gauges and leak proof connection. This technique allows us to drive a punctured vehicle which increases safety, comfort & saves time. This paper suggests a new technique towards one more improvement in our automobile industry.

  14. Experimental verification of the role of electron pressure in fast magnetic reconnection with a guide field

    DOE PAGES

    Fox, W.; Sciortino, F.; v. Stechow, A.; ...

    2017-03-21

    We report detailed laboratory observations of the structure of a reconnection current sheet in a two-fluid plasma regime with a guide magnetic field. We observe and quantitatively analyze the quadrupolar electron pressure variation in the ion-diffusion region, as originally predicted by extended magnetohydrodynamics simulations. The projection of the electron pressure gradient parallel to the magnetic field contributes significantly to balancing the parallel electric field, and the resulting cross-field electron jets in the reconnection layer are diamagnetic in origin. Furthermore, these results demonstrate how parallel and perpendicular force balance are coupled in guide field reconnection and confirm basic theoretical models ofmore » the importance of electron pressure gradients for obtaining fast magnetic reconnection.« less

  15. Lighter-Than-Air and Pressurized Structures Technology for Unmanned Aerial Vehicles (UAVs)

    DTIC Science & Technology

    2010-01-01

    through lighter-than-air or pressurized structures-based ( PSB ) technologies. Basically, we examined how to construct the UAV in such a way that a...considerable percentage of its weight will be supported by or composed of inflatable structures containing air or helium. In this way, PSB technology...will reduce the amount of energy required to keep the UAV aloft, thus allowing the use of smaller, slower, and quieter motors. Using PSB technology

  16. Effect of Winglets on a First-Generation Jet Transport Wing. 2: Pressure and Spanwise Load Distributions for a Semispan Model at High Subsonic Speeds. [in the Langley 8 ft transonic tunnel

    NASA Technical Reports Server (NTRS)

    Montoya, L. C.; Flechner, S. G.; Jacobs, P. F.

    1977-01-01

    Pressure and spanwise load distributions on a first-generation jet transport semispan model at high subsonic speeds are presented for the basic wing and for configurations with an upper winglet only, upper and lower winglets, and a simple wing-tip extension. Selected data are discussed to show the general trends and effects of the various configurations.

  17. Wide Band-Gap Semiconductors. 1991 Materials Research Society Symposium Proceedings

    DTIC Science & Technology

    1992-09-01

    attention of many research groups bccause the instrumental simplicity and high growth rate (1,2). One of the basic problems with this technique, other than...solution with group 1a element as a dopant under controlled Zn vapor pressure. p-n junction diodes are also prepared by the Ga diffusion from Zn solution...stoichiometric composition catl be controlled by the application of the vapor pressure. Mat. Res. Soc. Symp. Proc. Vol. 242. 1992 Materials Research Society 180

  18. Study of steam condensation at sub-atmospheric pressure: setting a basic research using MELCOR code

    NASA Astrophysics Data System (ADS)

    Manfredini, A.; Mazzini, M.

    2017-11-01

    One of the most serious accidents that can occur in the experimental nuclear fusion reactor ITER is the break of one of the headers of the refrigeration system of the first wall of the Tokamak. This results in water-steam mixture discharge in vacuum vessel (VV), with consequent pressurization of this container. To prevent the pressure in the VV exceeds 150 KPa absolute, a system discharges the steam inside a suppression pool, at an absolute pressure of 4.2 kPa. The computer codes used to analyze such incident (eg. RELAP 5 or MELCOR) are not validated experimentally for such conditions. Therefore, we planned a basic research, in order to have experimental data useful to validate the heat transfer correlations used in these codes. After a thorough literature search on this topic, ACTA, in collaboration with the staff of ITER, defined the experimental matrix and performed the design of the experimental apparatus. For the thermal-hydraulic design of the experiments, we executed a series of calculations by MELCOR. This code, however, was used in an unconventional mode, with the development of models suited respectively to low and high steam flow-rate tests. The article concludes with a discussion of the placement of experimental data within the map featuring the phenomenon characteristics, showing the importance of the new knowledge acquired, particularly in the case of chugging.

  19. Adult Basic Education Materials Evaluation Guide.

    ERIC Educational Resources Information Center

    Harrison, David

    This guide is intended for use by adult basic education practitioners in the screening of basic reading textbooks prior to their adoption for classroom use. The guide is in the form of a questionnaire and consists of dichotomous-choice questions arranged into three sections that relate to the product design, adult learning, and reading instruction…

  20. Starch Products. Learning Activity Pack and Instructor's Guide 5.9. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

    ERIC Educational Resources Information Center

    Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

    This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with some basic information about starches and with three starch products found throughout the world: cereals and rice, potatoes, and pasta. Illustrated…

  1. Basic characteristics and realization of production system control

    NASA Astrophysics Data System (ADS)

    Cheng, Shaopeng; Shell, Richard; Hall, Ernest L.

    1992-11-01

    This paper analyzes the issues involved in developing an intelligent production control system. It describes the basic characteristics of a production control system and an effective design methodology to realize the production control functions. Petri net, subsystem and hierarchical control concepts are applied to a computer integrated material handling system (MHS). Some communication and interface requirements of the MHS are also considered in this paper. The control system solution is illustrated with an actual MHS operation case which indicates that a truly flexible and integrated production system can be realized with a Petri net operation model and a hierarchical control structure. The significance of this work is related to the different operation testing and evaluation requirements encountered in manufacturing.

  2. Air Pressure Responses to Sudden Vocal Tract Pressure Bleeds during Production of Stop Consonants: New Evidence of Aeromechanical Regulation.

    ERIC Educational Resources Information Center

    Zajac, David J.; Weissler, Mark C.

    2004-01-01

    Two studies were conducted to evaluate short-latency vocal tract air pressure responses to sudden pressure bleeds during production of voiceless bilabial stop consonants. It was hypothesized that the occurrence of respiratory reflexes would be indicated by distinct patterns of responses as a function of bleed magnitude. In Study 1, 19 adults…

  3. Pressure ulcer prevention and management strategies in Turkey.

    PubMed

    Acaroglu, Rengin; Sendir, Merdiye

    2005-01-01

    Pressure ulcers are a serious problem that can lead to pain and delayed recovery. In Turkey, the selection of dressing products is usually left to the nurse managing the patient and depends on several factors, including the condition of the wound, the nurse's knowledge, and the nurse's experience. The aim of this study was to determine prevention and management strategies for pressure ulcer care in hospitalized patients in Turkey and to identify the factors that influence the selection of products by nurses. The descriptive study was carried out in various departments (orthopedic, neurological, oncology, and intensive care) where bedridden patients were found. A total of 110 nurses volunteered to participate. Data were collected by means of a questionnaire developed after a review of the literature. Only 32% of the nurses made use of a pressure ulcer care risk evaluation scale (Norton scale), and air mattresses were used by 89% as a preventive measure with patients who were at risk. When pressure ulcers occurred, advanced wound care products were preferred by most of the nurses. Seventy four percent of nurses considered the condition of wound for selection of products. Despite correctly noting several strategies for prevention of pressure ulcers, 9% of nurses also described massage around boney prominence and the use of inflatable rings as effective preventive strategies. This descriptive study shows that nurses in Turkey are primarily responsible for prevention and management of pressure ulcer care and that both traditional dressing products and advanced wound care products are used in the care of all stages of pressure ulcers in Turkey. It also illustrates the need for ongoing pressure ulcer education to promote evidence-based practice and reduce the use of ineffective (or harmful) strategies.

  4. The origin of bipedality as the result of a developmental by-product: The case study of the olive baboon (Papio anubis).

    PubMed

    Druelle, François; Aerts, Peter; Berillon, Gilles

    2017-12-01

    In this paper, we point to the importance of considering infancy in the emergence of new locomotor modes during evolution, and particularly when considering bipedal walking. Indeed, because infant primates commonly exhibit a more diverse posturo-locomotor repertoire than adults, the developmental processes of locomotion represent an important source of variation upon which natural selection may act. We have had the opportunity to follow the development of locomotion in captive individuals of a committed quadrupedal primate, the olive baboon (Papio anubis). We observed six infants at two different stages of their development. In total, we were able to analyze the temporal parameters of 65 bipedal steps, as well as their behavioral components. Our results show that while the basic temporal aspects of the bipedal walking gait (i.e., duty factor, dimensionless frequency, and hind lag) do not change during development, the baboon is able to significantly improve the coordination pattern between hind limbs. This probably influences the bout duration of spontaneous bipedal walking. During the same developmental stage, the interlimb coordination in quadrupedal walking is improved and the proportion of quadrupedal behaviors increases significantly. Therefore, the quadrupedal pattern of primates does not impede the developmental acquisition of bipedal behaviors. This may suggest that the same basic mechanism is responsible for controlling bipedal and quadrupedal locomotion, i.e., that in non-human primates, the neural networks for quadrupedal locomotion are also employed to perform (occasional) bipedal walking. In this context, a secondary locomotor mode (e.g., bipedalism) experienced during infancy as a by-product of locomotor development may lead to evolutionary novelties when under appropriate selective pressures. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. A switched energy saving position controller for variable-pressure electro-hydraulic servo systems.

    PubMed

    Tivay, Ali; Zareinejad, Mohammad; Rezaei, S Mehdi; Baghestan, Keivan

    2014-07-01

    The electro-hydraulic servo system (EHSS) demonstrates a relatively low level of efficiency compared to other available actuation methods. The objective of this paper is to increase this efficiency by introducing a variable supply pressure into the system and controlling this pressure during the task of position tracking. For this purpose, an EHSS structure with controllable supply pressure is proposed and its dynamic model is derived from the basic laws of physics. A switching control structure is then proposed to control both the supply pressure and the cylinder position at the same time, in a way that reduces the overall energy consumption of the system. The stability of the proposed switching control system is guaranteed by proof, and its performance is verified by experimental testing. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  6. Total Wellness and Holistic Health: A Bandwagon We Cannot Afford to Jump Onto

    ERIC Educational Resources Information Center

    Sechrist, William C.

    1979-01-01

    The changing public attitude towards "total wellness" creates pressure for health educators to desert the basic problem-oriented research programs in favor of nebulous, unmeasurable, but conspicuous targets such as "holistic health." (LH)

  7. Detoxification of aflatoxins on prospective approach: effect on structural, mechanical, and optical properties under pressures.

    PubMed

    Wei, Yong-Kai; Zhao, Xiao-Miao; Li, Meng-Meng; Yu, Jing-Xin; Gurudeeban, Selvaraj; Hu, Yan-Fei; Ji, Guang-Fu; Wei, Dong-Qing

    2018-06-01

    Aflatoxins are sequential of derivatives of coumarin and dihydrofuran with similar chemical structures and well-known carcinogenic agent. Many studies performed to detoxify aflatoxins, but the result is not ideal. Therefore, we studied structural, infrared spectrum, mechanical, and optical properties of these compounds in the aim of perspective physics. Mulliken charge distributions and infrared spectral analysis performed to understand the structural difference between the basic types of aflatoxins. In addition, the effect of pressure, different polarized, and incident directions on their structural changes was determined. It is found that AFB 1 is most stable structure among four basic types aflatoxins (AFB 1 , AFB 2 , AFG 1 , and AFG 2 ), and IR spectra are analyzed to exhibit the difference on structures of them. The mechanical properties of AFB 1 indicate that the structure of this toxin can be easily changed by pressure. The real [Formula: see text] and imaginary [Formula: see text] parts of the dielectric function, and the absorption coefficient [Formula: see text] and energy loss spectrum [Formula: see text] were also obtained under different polarized and incident directions. Furthermore, biological experiments needed to support the toxic level of AFB 1 using optical technologies.

  8. Pressure-sensing performance of upright cylinders in a Mach 10 boundary-layer

    NASA Technical Reports Server (NTRS)

    Johnson, Steven; Murphy, Kelly

    1994-01-01

    An experimental research program to provide basic knowledge of the pressure-sensing performance of upright, flushported cylinders in a hypersonic boundary layer is described. Three upright cylinders of 0.25-, 0.5- and l.0-in. diameters and a conventional rake were placed in the test section sidewall boundary layer of the 31 Inch Mach 10 Wind Tunnel at NASA Langley Research Center, Hampton, Virginia. Boundary-layer pressures from these cylinders were compared to those measured with a conventional rake. A boundary-layer thickness-to-cylinder-diameter ratio of 8 proved sufficient to accurately measure an overall pressure profile and ascertain the boundary-layer thickness. Effects of Reynolds number, flow angularity, and shock wave impingement on pressure measurement were also investigated. Although Reynolds number effects were negligible at the conditions studied, flow angularity above 10 deg significantly affects the measured pressures. Shock wave impingement was used to investigate orifice-to-orifice pressure crosstalk. No crosstalk was measured. The lower pressure measured above the oblique shock wave impingement showed no influence of the higher pressure generated at the lower port locations.

  9. Quantitative aspects of vibratory mobilization and break-up of non-wetting fluids in porous media

    NASA Astrophysics Data System (ADS)

    Deng, Wen

    Seismic stimulation is a promising technology aimed to mobilize the entrapped non-wetting fluids in the subsurface. The applications include enhanced oil recovery or, alternatively, facilitation of movement of immiscible/partly-miscible gases far into porous media, for example, for CO2 sequestration. This work is devoted to detailed quantitative studies of the two basic pore-scale mechanisms standing behind seismic stimulation: the mobilization of bubbles or drops entrapped in pore constrictions by capillary forces and the break-up of continuous long bubbles or drops. In typical oil-production operations, oil is produced by the natural reservoir-pressure drive during the primary stage and by artificial water flooding at the secondary stage. Capillary forces act to retain a substantial residual fraction of reservoir oil even after water flooding. The seismic stimulation is an unconventional technology that serves to overcome capillary barriers in individual pores and liberate the entrapped oil by adding an oscillatory inertial forcing to the external pressure gradient. According to our study, the effect of seismic stimulation on oil mobilization is highly dependent on the frequencies and amplitudes of the seismic waves. Generally, the lower the frequency and the larger the amplitude, more effective is the mobilization. To describe the mobilization process, we developed two theoretical hydrodynamics-based models and justified both using computational fluid dynamics (CFD). Our theoretical models have a significant advantage over CFD in that they reduce the computational time significantly, while providing correct practical guidance regarding the required field parameters of vibroseismic stimulation, such as the amplitude and frequency of the seismic field. The models also provide important insights into the basic mechanisms governing the vibration-driven two-phase flow in constricted capillaries. In a waterflooded reservoir, oil can be recovered most efficiently by forming continuous streams from isolated droplets. The longer the continuous oil phase under a certain pressure gradient, the more easily it overcomes its capillary barrier. However, surface tension between water and oil causes the typically non-wetting oil, constituting the core phase in the channels, to break up at the pore constriction into isolated beads, which inhibits further motion. The break-up thus counteracts the mobilization. We developed a theoretical model that provides an exact quantitative description of the dynamics of the oil-snap-off process. It also formulates a purely geometric criterion that controls, based on pore geometry only, whether the oil core phase stays continuous or disintegrates into droplets. Both the theoretical model and the break-criterion have been validated against CFD simulations. The work completed elucidates the basic physical mechanisms behind the enhanced oil recovery by seismic waves and vibrations. This creates a theoretical foundation for the further development of corresponding field technologies.

  10. [Microcystin safety study during Cyanobacteria removal by pressure enhanced coagulation process].

    PubMed

    Jiang, Xin-Yue; Luan, Qing; Cong, Hai-Bing; Xu, Si-Tao; Liu, Yu-Jiao; Zhu, Xue-Yuan

    2014-11-01

    Pressure enhanced coagulation and sedimentation technique is an effective way for blue algae treatment. It is not clear whether Cyanobacteria balloon rupture will cause Cyanobacteria cells rupture, resulting in high intracellular concentrations of microcystin LR leak into the water, affecting drinking water safety. Therefore, in this study experimental comparative study of pressure and pre-oxidation of water containing Cyanobacteria was carried out to examine the microcystin LR concentration changes and Cyanobacteria removal efficiency. The results showed that microcystin concentration increase was not significant by the pre-treatment with Cyanobacteria water pressure, while the pre-oxidation process caused a significant increase in the concentration of microcystin. After 0.5-0.8 MPa pressure coagulation and sedimentation, removal of Cyanobacteria basically was over 90%, up to 93.5%, while the removal rate by pre-oxidation was low and unstable. Effluent turbidity is also significantly better in the pre-pressure method than the pre-oxidation. The results indicated that pressure enhanced coagulation is a safe and reliable method for Cyanobacteria removal.

  11. Respiratory mechanics in mechanically ventilated patients.

    PubMed

    Hess, Dean R

    2014-11-01

    Respiratory mechanics refers to the expression of lung function through measures of pressure and flow. From these measurements, a variety of derived indices can be determined, such as volume, compliance, resistance, and work of breathing. Plateau pressure is a measure of end-inspiratory distending pressure. It has become increasingly appreciated that end-inspiratory transpulmonary pressure (stress) might be a better indicator of the potential for lung injury than plateau pressure alone. This has resulted in a resurgence of interest in the use of esophageal manometry in mechanically ventilated patients. End-expiratory transpulmonary pressure might also be useful to guide the setting of PEEP to counterbalance the collapsing effects of the chest wall. The shape of the pressure-time curve might also be useful to guide the setting of PEEP (stress index). This has focused interest in the roles of stress and strain to assess the potential for lung injury during mechanical ventilation. This paper covers both basic and advanced respiratory mechanics during mechanical ventilation. Copyright © 2014 by Daedalus Enterprises.

  12. Calculational and Experimental Investigations of the Pressure Effects on Radical - Radical Cross Combinations Reactions: C2H5 + C2H3

    NASA Technical Reports Server (NTRS)

    Fahr, Askar; Halpern, Joshua B.; Tardy, Dwight C.

    2007-01-01

    Pressure-dependent product yields have been experimentally determined for the cross-radical reaction C2H5 + C2H3. These results have been extended by calculations. It is shown that the chemically activated combination adduct, 1-C4H8*, is either stabilized by bimolecular collisions or subject to a variety of unimolecular reactions including cyclizations and decompositions. Therefore the "apparent" combination/disproportionation ratio exhibits a complex pressure dependence. The experimental studies were performed at 298 K and at selected pressures between about 4 Torr (0.5 kPa) and 760 Torr (101 kPa). Ethyl and vinyl radicals were simultaneously produced by 193 nm excimer laser photolysis of C2H5COC2H3 or photolysis of C2H3Br and C2H5COC2H5. Gas chromatograph/mass spectrometry/flame ionization detection (GC/MS/FID) were used to identify and quantify the final reaction products. The major combination reactions at pressures between 500 (66.5 kPa) and 760 Torr are (1c) C2H5 + C2H3 yields 1-butene, (2c) C2H5 + C2H5 yields n-butane, and (3c) C2H3 + C2H3 yields 1,3-butadiene. The major products of the disproportionation reactions are ethane, ethylene, and acetylene. At moderate and lower pressures, secondary products, including propene, propane, isobutene, 2-butene (cis and trans), 1-pentene, 1,4-pentadiene, and 1,5-hexadiene are also observed. Two isomers of C4H6, cyclobutene and/or 1,2-butadiene, were also among the likely products. The pressure-dependent yield of the cross-combination product, 1-butene, was compared to the yield of n-butane, the combination product of reaction (2c), which was found to be independent of pressure over the range of this study. The [ 1-C4H8]/[C4H10] ratio was reduced from approx.1.2 at 760 Torr (101 kPa) to approx.0.5 at 100 Torr (13.3 kPa) and approx.0.1 at pressures lower than about 5 Torr (approx.0.7 kPa). Electronic structure and RRKM calculations were used to simulate both unimolecular and bimolecular processes. The relative importance of C-C and C-H bond ruptures, cyclization, decyclization, and complex decompositions are discussed in terms of energetics and structural properties. The pressure dependence of the product yields were computed and dominant reaction paths in this chemically activated system were determined. Both modeling and experiment suggest that the observed pressure dependence of [1-C4H8]/[C4H10] is due to decomposition of the chemically activated combination adduct 1-C4H8* in which the weaker allylic C-C bond is broken: H2C=CHCH2CH3 yields C3H5 + CH3. This reaction occurs even at moderate pressures of approx.200 Torr (26 kPa) and becomes more significant at lower pressures. The additional products detected at lower pressures are formed from secondary radical-radical reactions involving allyl, methyl, ethyl, and vinyl radicals. The modeling studies have extended the predictions of product distributions to different temperatures (200-700 K) and a wider range of pressures (10(exp -3) - 10(exp 5) Torr). These calculations indicate that the high-pressure [1-C4H8]/[C4H10] yield ratio is 1.3 +/- 0.1.

  13. Formic Acid Formation by Clostridium ljungdahlii at Elevated Pressures of Carbon Dioxide and Hydrogen

    PubMed Central

    Oswald, Florian; Stoll, I. Katharina; Zwick, Michaela; Herbig, Sophia; Sauer, Jörg; Boukis, Nikolaos; Neumann, Anke

    2018-01-01

    Low productivities of bioprocesses using gaseous carbon and energy sources are usually caused by the low solubility of those gases (e.g., H2 and CO). It has been suggested that increasing the partial pressure of those gases will result in higher dissolved concentrations and should, therefore, be helpful to overcome this obstacle. Investigations of the late 1980s with mixtures of hydrogen and carbon monoxide showed inhibitory effects of carbon monoxide partial pressures above 0.8 bar. Avoiding any effects of carbon monoxide, we investigate growth and product formation of Clostridium ljungdahlii at absolute process pressures of 1, 4, and 7 bar in batch stirred tank reactor cultivations with carbon dioxide and hydrogen as sole gaseous carbon and energy source. With increasing process pressure, the product spectrum shifts from mainly acetic acid and ethanol to almost only formic acid at a total system pressure of 7 bar. On the other hand, no significant changes in overall product yield can be observed. By keeping the amount of substance flow rate constant instead of the volumetric gas feed rate when increasing the process pressure, we increased the overall product yield of 7.5 times of what has been previously reported in the literature. After 90 h of cultivation at a total pressure of 7 bar a total of 4 g L−1 of products is produced consisting of 82.7 % formic acid, 15.6 % acetic acid, and 1.7 % ethanol. PMID:29484294

  14. Enhanced Perfusion During Advanced Life Support Improves Survival With Favorable Neurologic Function in a Porcine Model of Refractory Cardiac Arrest

    PubMed Central

    Debaty, Guillaume; Metzger, Anja; Rees, Jennifer; McKnite, Scott; Puertas, Laura; Yannopoulos, Demetris; Lurie, Keith

    2016-01-01

    Objective To improve the likelihood for survival with favorable neurologic function after cardiac arrest, we assessed a new advanced life support approach using active compression-decompression cardiopulmonary resuscitation plus an intrathoracic pressure regulator. Design Prospective animal investigation. Setting Animal laboratory. Subjects Female farm pigs (n = 25) (39 ± 3 kg). Interventions Protocol A: After 12 minutes of untreated ventricular fibrillation, 18 pigs were randomized to group A—3 minutes of basic life support with standard cardiopulmonary resuscitation, defibrillation, and if needed 2 minutes of advanced life support with standard cardiopulmonary resuscitation; group B—3 minutes of basic life support with standard cardiopulmonary resuscitation, defibrillation, and if needed 2 minutes of advanced life support with active compression-decompression plus intrathoracic pressure regulator; and group C—3 minutes of basic life support with active compression-decompression cardiopulmonary resuscitation plus an impedance threshold device, defibrillation, and if needed 2 minutes of advanced life support with active compression-decompression plus intrathoracic pressure regulator. Advanced life support always included IV epinephrine (0.05 μg/kg). The primary endpoint was the 24-hour Cerebral Performance Category score. Protocol B: Myocardial and cerebral blood flow were measured in seven pigs before ventricular fibrillation and then following 6 minutes of untreated ventricular fibrillation during sequential 5 minutes treatments with active compression-decompression plus impedance threshold device, active compression-decompression plus intrathoracic pressure regulator, and active compression-decompression plus intrathoracic pressure regulator plus epinephrine. Measurements and Main Results Protocol A: One of six pigs survived for 24 hours in group A versus six of six in groups B and C (p = 0.002) and Cerebral Performance Category scores were 4.7 ± 0.8, 1.7 ± 0.8, and 1.0 ± 0, respectively (p = 0.001). Protocol B: Brain blood flow was significantly higher with active compression-decompression plus intrathoracic pressure regulator compared with active compression-decompression plus impedance threshold device (0.39 ± 0.23 vs 0.27 ± 0.14 mL/min/g; p = 0.03), whereas differences in myocardial perfusion were not statistically significant (0.65 ± 0.81 vs 0.42 ± 0.36 mL/min/g; p = 0.23). Brain and myocardial blood flow with active compression-decompression plus intrathoracic pressure regulator plus epinephrine were significantly increased versus active compression-decompression plus impedance threshold device (0.40 ± 0.22 and 0.84 ± 0.60 mL/min/g; p = 0.02 for both). Conclusion Advanced life support with active compression-decompression plus intrathoracic pressure regulator significantly improved cerebral perfusion and 24-hour survival with favorable neurologic function. These findings support further evaluation of this new advanced life support methodology in humans. PMID:25756411

  15. Data book for 12.5-inch diameter SRB thermal model water flotation test; 1.29 psia, series P022

    NASA Technical Reports Server (NTRS)

    Allums, S. L.

    1974-01-01

    Data acquired from tests conducted to determine how thermal conditions affect SRB (Space Shuttle Solid Rocket Booster) flotation at a scaled pressure of 1.29 psia are presented. Included are acceleration, pressure, and temperature data recorded from initial water impact to final flotation position using a 12.5-inch diameter thermal model of the SRB. Nineteen valid tests were conducted. These thermal tests indicated the following basic differences relative to the ambient temperature and pressure model tests: (1) more water was taken on board during penetration and (2) model flotation/sinking was temperature sensitive.

  16. An investigation of the unsteady flow associated with plume induced flow separation

    NASA Technical Reports Server (NTRS)

    Boggess, A. L., Jr.

    1972-01-01

    A wind tunnel study of the basic nature of plume induced flow separation is reported with emphasis on the unsteady aspects of the flow. Testing was conducted in a 6 inch by 6 inch blow-down supersonic wind tunnel. A cone-cylinder model with a pluming jet was used as the test model. Tests were conducted with a systematic variation in Mach number and plume pressure. Results of the tests are presented in the form of root-mean-squared surface pressure levels, power spectral densities, photographs of the flow field from which shock angles and separation lengths were taken, and time-averaged surface pressure profiles.

  17. Non-gravitational perturbations and satellite geodesy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milani, A.; Nobill, A.M.; Farinella, P.

    1987-01-01

    This book presents the basic ideas of the physics of non-gravitational perturbations and the mathematics required to compute their orbital effects. It conveys the relevance of the different problems that must be solved to achieve a given level of accuracy in orbit determination and in recovery of geophysically significant parameters. Selected Contents are: Orders of Magnitude of the Perturbing Forces, Tides and Apparent Forces, Tools from Celestial Mechanics, Solar Radiation Pressure-Direct Effects: Satellite-Solar Radiation Interaction, Long-Term Effects on Semi-Major Axis, Radiation Pressure-Indirect Effects: Earth-Reflected Radiation Pressure, Anisotropic Thermal Emission, Drag: Orbital Perturbations by a Drag-Like Force, and Charged Particle Drag.

  18. Integrating basic science in academic cardiology training: two international perspectives on a common challenge.

    PubMed

    Bode, Michael F; Hilgendorf, Ingo

    2018-06-09

    Political bodies and professional societies acknowledge that translational research benefits from researchers trained in both, clinical medicine and basic science. Yet, few physicians undergoing clinical training in cardiology seek this dual career (Milewicz et al. J Clin Invest 125:3742-3747, 2015). The reasons are likely manifold, but with cardiology having become increasingly interventional and facing economic pressure, how much attention, credit, and encouragement is given to physicians interested in basic cardiovascular science? Having studied and worked in hospitals and laboratories, in both Germany and the USA, we aim to compare in this article how basic science education is currently integrated into cardiology training at German and US university hospitals, from medical school to more advanced career stages. By doing so, we hope to provide some outside perspectives to young physicians and decision makers alike, that may inspire changes to curricula in the respective countries and around the world.

  19. Replacement bearing for Rocketdyne SSME HPOTPs using alternate self-lubricating retainer materials

    NASA Technical Reports Server (NTRS)

    Gleeson, J.; Dufrane, K.; Kannel, J.

    1992-01-01

    Research was conducted to develop replacement bearings for the Rocketdyne Space Shuttle main engine (SSME) high pressure oxidizer turbopumps (HPOTPs). The replacement bearings consisted of standard balls and races with a special Battelle Self-Lubricating Insert Configuration (BASIC) retainer. The BASIC retainer consists of a phosphor bronze housing with inserts consisting of a polytetrafluoretheylene (PTFE) and bronze compound. The PTFE contacts the balls and the land guiding surface on the outer race. A PTFE transfer film is formed on balls and races, which lubricates the critical interfaces. The BASIC retainer is a one-to-one replacement for the current Armalon retainer, but has superior lubricating properties and is stronger over the broad temperature range anticipated for the HPOTP bearings. As a part of the project 40 sets of balls and races (two sizes) and 52 BASIC retainers were shipped to NASA/MSFC.

  20. 21 CFR 346.50 - Labeling of anorectal drug products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... (i) “Do not use this product if you have heart disease, high blood pressure, thyroid disease... for high blood pressure or depression.” 1 See § 201.66(b)(4) of this chapter. (iii) For products...

  1. 21 CFR 346.50 - Labeling of anorectal drug products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... (i) “Do not use this product if you have heart disease, high blood pressure, thyroid disease... for high blood pressure or depression.” 1 See § 201.66(b)(4) of this chapter. (iii) For products...

  2. 21 CFR 346.50 - Labeling of anorectal drug products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... (i) “Do not use this product if you have heart disease, high blood pressure, thyroid disease... for high blood pressure or depression.” 1 See § 201.66(b)(4) of this chapter. (iii) For products...

  3. Rehabilitating acid soils for increasing crop productivity through low-cost liming material.

    PubMed

    Bhat, Javid Ahmad; Kundu, Manik Chandra; Hazra, Gora Chand; Santra, Gour Hari; Mandal, Biswapati

    2010-09-15

    Productivity of red and lateritic soils is low because of their acidity and deficiencies in few essential nutrients viz., nitrogen, phosphorus, calcium, zinc, boron, molybdenum etc. We compared the effectiveness of basic slag, a low-cost liming material, with that of calcite as an ameliorant for these soils using mustard followed by rice as test crops. Experiments were conducted with three levels of each of basic slag and calcite along with a control on farmers' fields at 14 different locations. Influence of farmyard manure (FYM) and poultry manure (PM) on the effectiveness of the slag was also tested. On an average, basic slag performed better than calcite in increasing yields of both mustard and rice and left over higher amounts of available Ca, Si and Zn in residual soils. The slag also improved N, P, K and Ca nutrition of mustard and Si and Zn nutrition of rice with a favorable benefit:cost (B:C) ratio over the calcite (4.82 vs. 1.44). Effectiveness of the basic slag improved when it was applied in combination with FYM or PM (B:C, 5.83 and 6.27). Basic slag can, therefore, be advocated for use in the acidic red and lateritic soils for economically improving their productivity. Copyright 2010 Elsevier B.V. All rights reserved.

  4. Air Pressure Responses to Sudden Vocal Tract Pressure Bleeds During Production of Stop Consonants: New Evidence of Aeromechanical Regulation

    PubMed Central

    Zajac, David J.; Weissler, Mark C.

    2011-01-01

    Two studies were conducted to evaluate short-latency vocal tract air pressure responses to sudden pressure bleeds during production of voiceless bilabial stop consonants. It was hypothesized that the occurrence of respiratory reflexes would be indicated by distinct patterns of responses as a function of bleed magnitude. In Study 1, 19 adults produced syllable trains of /pΛ/ using a mouthpiece coupled to a computer-controlled perturbator. The device randomly created bleed apertures that ranged from 0 to 40 mm2 during production of the 2nd or 4th syllable of an utterance. Although peak oral air pressure dropped in a linear manner across bleed apertures, it averaged 2 to 3 cm H2O at the largest bleed. While slope of oral pressure also decreased in a linear trend, duration of the oral pressure pulse remained relatively constant. The patterns suggest that respiratory reflexes, if present, have little effect on oral air pressure levels. In Study 2, both oral and subglottal air pressure responses were monitored in 2 adults while bleed apertures of 20 and 40 mm2 were randomly created. For 1 participant, peak oral air pressure dropped across bleed apertures, as in Study 1. Subglottal air pressure and slope, however, remained relatively stable. These patterns provide some support for the occurrence of respiratory reflexes to regulate subglottal air pressure. Overall, the studies indicate that the inherent physiologic processes of the respiratory system, which may involve reflexes, and passive aeromechanical resistance of the upper airway are capable of developing oral air pressure in the face of substantial pressure bleeds. Implications for understanding speech production and the characteristics of individuals with velopharyngeal dysfunction are discussed. PMID:15324286

  5. Effect of high pressure on physicochemical properties of meat.

    PubMed

    Buckow, Roman; Sikes, Anita; Tume, Ron

    2013-01-01

    The application of high pressure offers some interesting opportunities in the processing of muscle-based food products. It is well known that high-pressure processing can prolong the shelf life of meat products in addition to chilling but the pressure-labile nature of protein systems limits the commercial range of applications. High pressure can affect the texture and gel-forming properties of myofibrillar proteins and, hence, has been suggested as a physical and additive-free alternative to tenderize and soften or restructure meat and fish products. However, the rate and magnitude at which pressure and temperature effects take place in muscles are variable and depend on a number of circumstances and conditions that are still not precisely known. This review provides an overview of the current knowledge of the effects of high pressure on muscle tissue over a range of temperatures as it relates to meat texture, microstructure, color, enzymes, lipid oxidation, and pressure-induced gelation of myofibrillar proteins.

  6. 40 CFR 86.085-37 - Production vehicles and engines.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... transmission class. (2) Base level means a unique combination of basic engine, inertia weight, and transmission class. (3) Vehicle configuration means a unique combination of basic engine, engine code, inertia weight...

  7. The perceived compatibility of safety and production expectations in hazardous occupations.

    PubMed

    McLain, David L; Jarrell, Kimberly A

    2007-01-01

    Safety hazards are unavoidable in many work environments. Employees must be both productive and safe, however, conflicting safety and production demands can negatively affect safety, production, or both. The employee's perception of the compatibility of management's safety and production expectations is a possible predictor of such consequences. This paper defines "safety-production compatibility" and describes how measures of safety-production compatibility, as well as safety pressure and production pressure, were developed. We used LISREL structural equation modeling to test the influences of safety-production compatibility, safety pressure, and production pressure on safe work behavior and interference with performing other work tasks. The 239 study participants were workers employed in diverse but hazardous occupations. Pressure to work safely was positively associated with safe work behavior. The perceived compatibility of safety and production demands positively influenced safe work behavior and reduced the interference of safety hazards performing other tasks. Safety-production compatibility was also found to mediate the relationship between trust in management and safe work behavior. The results of this field study suggest increased compatibility, and thus less conflict, between safety and production demands influences safe work behavior and the interference of safety hazards with performing other work tasks. More broadly, the worker's reaction to multiple work demands is a safety and performance influence. Safety management efforts that focus only on the hazards fail to eliminate many accidents because accidents arise from many factors including technology, safety climate, social influences, production, and safety demands. This study suggests that workers differ in their perception of the compatibility of safety and production demands. These differences will show up in safe work behavior, influencing the effectiveness of safety management efforts and the trust workers have in management's concern for safety.

  8. Prevention of Ventilator-Associated Pneumonia in the Intensive Care Unit: Beyond the Basics.

    PubMed

    Larrow, Vickie; Klich-Heartt, Eira I

    2016-06-01

    Ventilated-associated pneumonia (VAP) is a major concern for hospitals and a major problem for ventilated patients in the intensive care unit. Included in the basics are hand hygiene, wearing gloves, endotracheal tube suctioning, head of bed at 30°, stress ulcer prophylaxis, turning patient side to side at least every two hours, and giving the patient a sedation vacation each morning. Beyond the basics included here are oral hygiene, oral suctioning, endotracheal tube cuff pressure, artificial humidification, the difference in practice between registered nurses and respiratory therapists, using the beach chair position and early mobilization, and the VAP bundle. The prevention of VAP becomes the focus for both nurses and respiratory therapists working with patients who are ventilated.

  9. A quantitative comparison of corrective and perfective maintenance

    NASA Technical Reports Server (NTRS)

    Henry, Joel; Cain, James

    1994-01-01

    This paper presents a quantitative comparison of corrective and perfective software maintenance activities. The comparison utilizes basic data collected throughout the maintenance process. The data collected are extensive and allow the impact of both types of maintenance to be quantitatively evaluated and compared. Basic statistical techniques test relationships between and among process and product data. The results show interesting similarities and important differences in both process and product characteristics.

  10. Enhancing Science Teaching through Performing Marbling Art Using Basic Solutions and Base Indicators

    ERIC Educational Resources Information Center

    Çil, Emine; Çelik, Kevser; Maçin, Tuba; Demirbas, Gülay; Gökçimen, Özlem

    2014-01-01

    Basic solutions are an indispensable part of our daily life. Basic solutions are commonly used in industries such as the textile industry, oil refineries, the fertilizer industry, and pharmaceutical products. Most cleaning agents, such as soap, detergent, and bleach, and some of our foods, such as chocolate and eggs, include bases. Bases are the…

  11. Anaerobic Digestion I. Sludge Treatment and Disposal Course #166. Instructor's Guide [and] Student Workbook.

    ERIC Educational Resources Information Center

    Arasmith, E. E.

    This lesson is the first of a two-part series on anaerobic digestion. Topics discussed include the five basic functions of an anaerobic digester, basic theory of the biological processes involved, basic equipment necessary for digestion, and the products of digestion. The lesson includes an instructor's guide and student workbook. The instructor's…

  12. 75 FR 52737 - Pesticide Product Registrations; Unconditional and Conditional Approvals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... extent of potential exposure. Based on these reviews, the Agency was able to make basic health and safety.... Based on these reviews, the Agency was able to make basic health and safety determinations that show use.... Based on these reviews, the Agency was able to make basic health and safety determinations that show use...

  13. FAST TRACK COMMUNICATION: Effects of Penning ionization on the discharge patterns of atmospheric pressure plasma jets

    NASA Astrophysics Data System (ADS)

    Li, Qing; Zhu, Wen-Chao; Zhu, Xi-Ming; Pu, Yi-Kang

    2010-09-01

    Atmospheric pressure plasma jets, generated in a coaxial dielectric barrier discharge configuration, have been investigated with different flowing gases. Discharge patterns in different tube regions were compared in the flowing gases of helium, neon and krypton. To explain the difference of these discharge patterns, a theoretical analysis is presented to reveal the possible basic processes. A comparison of experimental and theoretical results identifies that Penning ionization is mainly responsible for the discharge patterns of helium and neon plasma jets.

  14. Precision closed bomb calorimeter for testing flame and gas producing initiators

    NASA Technical Reports Server (NTRS)

    Carpenter, D. R., Jr.; Taylor, A. C., Jr.

    1972-01-01

    A calorimeter has been developed under this study to help meet the needs of accurate performance monitoring of electrically or mechanically actuated flame and gas producing devices, such as squib-type initiators. A ten cubic centimeter closed bomb (closed volume) calorimeter was designed to provide a standard pressure trace and to measure a nominal 50 calorie output, using the basic components of a Parr Model 1411 calorimeter. Two prototype bombs were fabricated, pressure tested to 2600 psi, and extensively evaluated.

  15. A Study of the Time Dependence in Fracture Processes Relating to Service Life Prediction of Adhesive Joints and Advanced Composites.

    DTIC Science & Technology

    1981-04-30

    fluid temperature should exceed 145°F. The flow control module contains all the hydraulic circuit elements necessary for both the pressure line to and...are contained in three basic modules : 1) the hydraulic power supply, 2) a flow control module containing valving, accumulators and filters, and 3) the...hydraulic transient overpressures, is located in the flow control module , as are the high and low pressure filters. The load frame (MTS Systems Corp

  16. Effect of winglets on a first-generation jet transport wing. 3: Pressure and spanwise load distributions for a semispan model at Mach 0.30. [in the Langley 8 ft transonic tunnel

    NASA Technical Reports Server (NTRS)

    Montoya, L. C.; Jacobs, P. F.; Flechner, S. G.

    1977-01-01

    Pressure and spanwise load distributions on a first-generation jet transport semispan model at a Mach number of 0.30 are given for the basic wing and for configurations with an upper winglet only, upper and lower winglets, and a simple wing-tip extension. To simulate second-segment-climb lift conditions, leading- and/or trailing-edge flaps were added to some configurations.

  17. Boundary-Layer Transition Detection in Cryogenic Wind Tunnel Using Fluorescent Paints

    NASA Technical Reports Server (NTRS)

    Sullivan, John

    1999-01-01

    Luminescent molecular probes imbedded in a polymer binder form a temperature or pressure paint. On excitation by light of the proper wavelength, the luminescence, which is quenched either thermally or by oxygen, is detected by a camera or photodetector. From the detected luminescent intensity, temperature and pressure can be determined. The basic photophysics, calibration, accuracy and time response of a luminescent paints is described followed by applications in low speed, transonic, supersonic and cryogenic wind tunnels and in rotating machinery.

  18. Effect of soy isoflavone supplementation on nitric oxide metabolism and blood pressure in menopausal women

    USDA-ARS?s Scientific Manuscript database

    Isoflavones, having chemical structures similar to estrogens, are believed to stimulate nitric oxide production and thus lower blood pressure. The efficacy of soy isoflavone supplementation to stimulate nitric oxide production and lower blood pressure in menopausal women with high normal blood press...

  19. Evaluating the federal role in financing health-related research

    PubMed Central

    Garber, Alan M.; Romer, Paul M.

    1996-01-01

    This paper considers the appropriate role for government in the support of scientific and technological progress in health care; the information the federal government needs to make well-informed decisions about its role; and the ways that federal policy toward research and development should respond to scientific advances, technology trends, and changes in the political and social environment. The principal justification for government support of research rests upon economic characteristics that lead private markets to provide inappropriate levels of research support or to supply inappropriate quantities of the products that result from research. The federal government has two basic tools for dealing with these problems: direct subsidies for research and strengthened property rights that can increase the revenues that companies receive for the products that result from research. In the coming years, the delivery system for health care will continue to undergo dramatic changes, new research opportunities will emerge at a rapid pace, and the pressure to limit discretionary federal spending will intensify. These forces make it increasingly important to improve the measurement of the costs and benefits of research and to recognize the tradeoffs among alternative policies for promoting innovation in health care. PMID:8917484

  20. Investigation of Rotating Stall Phenomena in Axial Flow Compressors. Volume I. Basic Studies of Rotating Stall

    DTIC Science & Technology

    1976-06-01

    rotating stall control system which was tested both on a low speed rig and a J-85-S engine. The second objective was to perform fundamental studies of the...Stator Stage 89 6 Annular Cascade Configuration Used for Rotating Stall Studies on Rotoi-Stator Stage ..... .............. ... 90 7 Static Pressure Rise...ground tests on a J-8S-S turbojet engine. The work i3 reported in three separate volumes. Volume I entitled, "Basic Studies of Rotating Stall", covers

  1. Force/torque and tactile sensors for sensor-based manipulator control

    NASA Technical Reports Server (NTRS)

    Vanbrussel, H.; Belieen, H.; Bao, Chao-Ying

    1989-01-01

    The autonomy of manipulators, in space and in industrial environments, can be dramatically enhanced by the use of force/torque and tactile sensors. The development and future use of a six-component force/torque sensor for the Hermes Robot Arm (HERA) Basic End-Effector (BEE) is discussed. Then a multifunctional gripper system based on tactile sensors is described. The basic transducing element of the sensor is a sheet of pressure-sensitive polymer. Tactile image processing algorithms for slip detection, object position estimation, and object recognition are described.

  2. Energy Saving Melting and Revert Reduction (E-SMARRT): Precision Casting of Steel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dr. Von L. Richards

    2011-09-30

    This project addresses improvements in metal casting processes by reducing scrap and reducing the cost of production, due to scrap reduction from investment casting and yield improvement offered by lost foam casting as compared to no-bake or green sand molding. The objectives for the investment casting portion of the subtask are to improve knowledge of fracture toughness of mold shells and the sources of strength limiting flaws and to understand the effects of wax reclamation procedures on wax properties. Applying 'clean steel' approaches to pouring technology and cleanliness in investment casting of steel are anticipated to improve incoming materials inspectionmore » procedures as they affect the microstructure and toughness of the shell. This project focused on two areas of study in the production of steel castings to reduce scrap and save energy: (1) Reducing the amount of shell cracking in investment cast steel production; (2) Investigate the potential of lost foam steel casting The basic findings regarding investment casting shell cracking were: (1) In the case of post pouring cracking, this could be related to phase changes in silica upon cooling and could be delayed by pouring arrangement strategies that maintained the shell surface at temperature for longer time. Employing this delay resulted in less adherent oxidation of castings since the casting was cooler at the time o fair exposure. (2) A model for heat transfer through water saturated shell materials under steam pressure was developed. (3) Initial modeling result of autoclave de-waxing indicated the higher pressure and temperature in the autoclave would impose a steeper temperature gradient on the wax pattern, causing some melt flow prior to bulk expansion and decreasing the stress on the green shell. Basic findings regarding lost foam casting of steel at atmospheric pressure: (1) EPS foam generally decomposes by the collapse mode in steel casting. (2) There is an accumulation of carbon pick-up at the end of the casting opposite the gate. (3) It is recommended that lost foam castings in steel be gated for a quiescent fill in an empty cavity mold to prevent foam occlusion defects from the collapse mode. The energy benefit is primarily in yield savings and lower casting weight per function due to elimination of draft and parting lines for the larger lost foam castings. For the smaller investment casting, scrap losses due to shell cracking will be reduced. Both of these effects will reduce the metal melted per good ton of castings. There will also be less machine stock required per casting which is a yield savings and a small additional energy savings in machining. Downstream savings will come from heavy truck and railroad applications. Application of these processes to heavy truck castings will lighten the heavy truck fleet by about ten pounds per truck. Using ten years to achieve full penetration of the truck fleet at linear rate this will result in a fuel savings of 131 trillion BTU over ten years.« less

  3. Investigation of scaling characteristics for defining design environments due to transient ground winds and near-field, nonlinear acoustic fields

    NASA Technical Reports Server (NTRS)

    Shih, C. C.

    1973-01-01

    In order to establish a foundation of scaling laws for the highly nonlinear waves associated with the launch vehicle, the basic knowledge of the relationships among the paramaters pertinent to the energy dissipation process associated with the propagation of nonlinear pressure waves in thermoviscous media is required. The problem of interest is to experimentally investigate the temporal and spacial velocity profiles of fluid flow in a 3-inch open-end pipe of various lengths, produced by the propagation of nonlinear pressure waves for various diaphragm burst pressures of a pressure wave generator. As a result, temporal and spacial characteristics of wave propagation for a parametric set of nonlinear pressure waves in the pipe containing air under atmospheric conditions were determined. Velocity measurements at five sections along the pipes of up to 210 ft. in length were made with hot-film anemometers for five pressure waves produced by a piston. The piston was derived with diaphragm burst pressures at 20, 40, 60, 80 and 100 psi in the driver chamber of the pressure wave generator.

  4. Aortic Baroreceptors Display Higher Mechanosensitivity than Carotid Baroreceptors.

    PubMed

    Lau, Eva On-Chai; Lo, Chun-Yin; Yao, Yifei; Mak, Arthur Fuk-Tat; Jiang, Liwen; Huang, Yu; Yao, Xiaoqiang

    2016-01-01

    Arterial baroreceptors are mechanical sensors that detect blood pressure changes. It has long been suggested that the two arterial baroreceptors, aortic and carotid baroreceptors, have different pressure sensitivities. However, there is no consensus as to which of the arterial baroreceptors are more sensitive to changes in blood pressure. In the present study, we employed independent methods to compare the pressure sensitivity of the two arterial baroreceptors. Firstly, pressure-activated action potential firing was measured by whole-cell current clamp with a high-speed pressure clamp system in primary cultured baroreceptor neurons. The results show that aortic depressor neurons possessed a higher percentage of mechano-sensitive neurons. Furthermore, aortic baroreceptor neurons show a lower pressure threshold than that of carotid baroreceptor neurons. Secondly, uniaxial stretching of baroreceptor neurons, that mimics the forces exerted on blood vessels, elicited a larger increase in intracellular Ca(2+) rise in aortic baroreceptor neurons than in carotid baroreceptor neurons. Thirdly, the pressure-induced action potential firing in the aortic depressor nerve recorded in vivo was also higher. The present study therefore provides for a basic physiological understanding on the pressure sensitivity of the two baroreceptor neurons and suggests that aortic baroreceptors have a higher pressure sensitivity than carotid baroreceptors.

  5. Infrared Multiphoton Dissociation of Peptide Cations in a Dual Pressure Linear Ion Trap Mass Spectrometer

    PubMed Central

    Gardner, Myles W.; Smith, Suncerae I.; Ledvina, Aaron R.; Madsen, James A.; Coon, Joshua J.; Schwartz, Jae C.; Stafford, George C.; Brodbelt, Jennifer S.

    2009-01-01

    A dual pressure linear ion trap mass spectrometer was modified to permit infrared multiphoton dissociation (IRMPD) in each of the two cells - the first a high pressure cell operated at nominally 5 × 10-3 Torr and the second a low pressure cell operated at nominally 3 × 10-4 Torr. When IRMPD was performed in the high pressure cell, most peptide ions did not undergo significant photodissociation; however, in the low pressure cell peptide cations were efficiently dissociated with less than 25 ms of IR irradiation regardless of charge state. IRMPD of peptide cations allowed the detection of low m/z product ions including the y1 fragments and immonium ions which are not typically observed by ion trap collision induced dissociation (CID). Photodissociation efficiencies of ~100% and MS/MS (tandem mass spectrometry) efficiencies of greater than 60% were observed for both multiply and singly protonated peptides. In general, higher sequence coverage of peptides was obtained using IRMPD over CID. Further, greater than 90% of the product ion current in the IRMPD mass spectra of doubly charged peptide ions was composed of singly charged product ions compared to the CID mass spectra in which the abundances of the multiply and singly charged product ions were equally divided. Highly charged primary product ions also underwent efficient photodissociation to yield singly charged secondary product ions, thus simplifying the IRMPD product ion mass spectra. PMID:19739654

  6. High-pressure studies on heavy fermion systems

    NASA Astrophysics Data System (ADS)

    Ye, Chen; Zongfa, Weng; Smidman, Michael; Xin, Lu; Huiqiu, Yuan

    2016-07-01

    In this review article, we give a brief overview of heavy fermions, which are prototype examples of strongly correlated electron systems. We introduce the application of physical pressure in heavy fermion systems to construct their pressure phase diagrams and to study the close relationship between superconductivity (SC) and other electronic instabilities, such as antiferromagnetism (AFM), ferromagnetism (FM), and valence transitions. Field-angle dependent heat capacity and point-contact spectroscopic measurements under pressure are taken as examples to illustrate their ability to investigate novel physical properties of the emergent electronic states. Project supported by the National Basic Research Program of China (Grant No. 2011CBA00103), the National Natural Science Foundation of China (Grant Nos. 11174245 and 11374257), the Science Challenge Program of China, and the Fundamental Research Funds for the Central Universities of China.

  7. Techno-economic Analysis of Acid Gas Removal and Liquefaction for Pressurized LNG

    NASA Astrophysics Data System (ADS)

    Lee, S. H.; Seo, Y. K.; Chang, D. J.

    2018-05-01

    This study estimated the life cycle cost (LCC) of an acid gas removal and a liquefaction processes for Pressurized LNG (PLNG) production and compared the results with the cost of normal LNG production. PLNG is pressurized LNG that is liquefied at a higher pressure and temperature than normal LNG. Due to the high temperature, the energy for liquefaction is reduced. The allowable CO2 concentration in PLNG is increased up to 3 mol% when the product pressure 25 bar. An amine process with 35 wt% of diethanolamine (DEA) aqueous solution and a nitrogen expansion cycle were selected for the acid gas removal and the liquefaction processes, respectively. Two types of CO2 concentration in the feed gas were investigated to analyze their impacts on the acid gas removal unit. When the CO2 concentration was 5 mol%, the acid gas removal unit was required for both LNG and PLNG production. However, the acid gas removal unit was not necessary in PLNG when the concentration was 0.5 mol% and the pressure was higher than 15 bar. The results showed that the LCC of PLNG was reduced by almost 35% relative to that of LNG when the PLNG pressure was higher than 15 bar.

  8. Methyl Chloroform Elimination from the Production of Space Shuttle Sold Rocket Motors

    NASA Technical Reports Server (NTRS)

    Golde, Rick P.; Burt, Rick; Key, Leigh

    1997-01-01

    Thiokol Space Operations manufactures the Reusable Solid Rocket Motors used to launch America's fleet of Space Shuttles. In 1989, Thiokol used more than 1.4 Mlb of methyl chloroform to produce rocket motors. The ban placed by the Environmental Protection Agency on the sale of methyl chloroform had a significant effect on future Reusable Solid Rocket Motor production. As a result, changes in the materials and processes became necessary. A multiphased plan was established by Thiokol in partnership with NASA's Marshall Space Flight Center to eliminate the use of methyl chloroform in the Reusable Solid Rocket Motor production process. Because of the extensive scope of this effort, the plan was phased to target the elimination of the majority of methyl chloroform use (90 percent) by January 1, 1996, the 3 Environmental Protection Agency deadline. Referred to as Phase I, this effort includes the elimination of two large vapor degreasers, grease diluent processes, and propellant tooling handcleaning using methyl chloroform. Meanwhile, a request was made for an essential use exemption to allow the continued use of the remaining 10 percent of methyl chloroform after the 1996 deadline, while total elimination was pursued for this final, critical phase (Phase II). This paper provides an update to three previous presentations prepared for the 1993, 1994, and 1995 CFC/Halon Alternative Conferences, and will outline the overall Ozone Depleting Compounds Elimination Program from the initial phases through the final testing and implementation phases, including facility and equipment development. Processes and materials to be discussed include low-pressure aqueous wash systems, high-pressure water blast systems- environmental shipping containers, aqueous and semi-aqueous cleaning solutions, and bond integrity and inspection criteria. Progress toward completion of facility implementation and lessons learned during the scope of the program, as well as the current development efforts and basic requirements of future methyl chloroform handcleaning elimination, will also be outlined.

  9. Analyzing Axial Stress and Deformation of Tubular for Steam Injection Process in Deviated Wells Based on the Varied (T, P) Fields

    PubMed Central

    Liu, Yunqiang; Xu, Jiuping; Wang, Shize; Qi, Bin

    2013-01-01

    The axial stress and deformation of high temperature high pressure deviated gas wells are studied. A new model is multiple nonlinear equation systems by comprehensive consideration of axial load of tubular string, internal and external fluid pressure, normal pressure between the tubular and well wall, and friction and viscous friction of fluid flowing. The varied temperature and pressure fields were researched by the coupled differential equations concerning mass, momentum, and energy equations instead of traditional methods. The axial load, the normal pressure, the friction, and four deformation lengths of tubular string are got ten by means of the dimensionless iterative interpolation algorithm. The basic data of the X Well, 1300 meters deep, are used for case history calculations. The results and some useful conclusions can provide technical reliability in the process of designing well testing in oil or gas wells. PMID:24163623

  10. Flow and Force Equations for a Body Revolving in a Fluid

    NASA Technical Reports Server (NTRS)

    Zahm, A. F.

    1979-01-01

    A general method for finding the steady flow velocity relative to a body in plane curvilinear motion, whence the pressure is found by Bernoulli's energy principle is described. Integration of the pressure supplies basic formulas for the zonal forces and moments on the revolving body. The application of the steady flow method for calculating the velocity and pressure at all points of the flow inside and outside an ellipsoid and some of its limiting forms is presented and graphs those quantities for the latter forms. In some useful cases experimental pressures are plotted for comparison with theoretical. The pressure, and thence the zonal force and moment, on hulls in plane curvilinear flight are calculated. General equations for the resultant fluid forces and moments on trisymmetrical bodies moving through a perfect fluid are derived. Formulas for potential coefficients and inertia coefficients for an ellipsoid and its limiting forms are presented.

  11. Capillary Pressure of a Liquid Between Uniform Spheres Arranged in a Square-Packed Layer

    NASA Technical Reports Server (NTRS)

    Alexader, J. Iwan D.; Slobozhanin, Lev A.; Collicott, Steven H.

    2004-01-01

    The capillary pressure in the pores defined by equidimensional close-packed spheres is analyzed numerically. In the absence of gravity the menisci shapes are constructed using Surface Evolver code. This permits calculation the free surface mean curvature and hence the capillary pressure. The dependences of capillary pressure on the liquid volume constructed here for a set of contact angles allow one to determine the evolution of basic capillary characteristics under quasi-static infiltration and drainage. The maximum pressure difference between liquid and gas required for a meniscus passing through a pore is calculated and compared with that for hexagonal packing and with approximate solution given by Mason and Morrow [l]. The lower and upper critical liquid volumes that determine the stability limits for the equilibrium capillary liquid in contact with square packed array of spheres are tabulated for a set of contact angles.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hushur, Anwar; Manghnani, Murli H.; Werheit, Helmut

    Single-crystal B4.3C boron carbide is investigated concerning the pressure-dependence of optical properties and of Raman-active phonons up to ~70 GPa. The high concentration of structural defects determining the electronic properties of boron carbide at ambient conditions initially decrease and finally vanish with pressure increasing. We obtain this immediately from transparency photos, allowing to estimate the pressure-dependent variation of the absorption edge rapidly increasing around 55 GPa. Glass-like transparency at pressures exceeding 60 GPa indicate that the width of the band exceeds ~3.1 eV thus making boron carbide a wide-gap semiconductor. Furthermore, the spectra of Raman–active phonons indicate a pressure-dependent phasemore » transition in single-crystal natB4.3C boron carbide near 35 GPa., particularly related to structural changes in connection with the C-B-C chains, while the basic icosahedral structure remains largely unaffected.« less

  13. High nitrogen pressure solution growth of GaN

    NASA Astrophysics Data System (ADS)

    Bockowski, Michal

    2014-10-01

    Results of GaN growth from gallium solution under high nitrogen pressure are presented. Basic of the high nitrogen pressure solution (HNPS) growth method is described. A new approach of seeded growth, multi-feed seed (MFS) configuration, is demonstrated. The use of two kinds of seeds: free-standing hydride vapor phase epitaxy GaN (HVPE-GaN) obtained from metal organic chemical vapor deposition (MOCVD)-GaN/sapphire templates and free-standing HVPE-GaN obtained from the ammonothermally grown GaN crystals, is shown. Depending on the seeds’ structural quality, the differences in the structural properties of pressure grown material are demonstrated and analyzed. The role and influence of impurities, like oxygen and magnesium, on GaN crystals grown from gallium solution in the MFS configuration is presented. The properties of differently doped GaN crystals are discussed. An application of the pressure grown GaN crystals as substrates for electronic and optoelectronic devices is reported.

  14. Structural Integrity and Durability of Reusable Space Propulsion Systems

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The space shuttle main engine (SSME), a reusable space propulsion system, is discussed. The advances in high pressure oxygen hydrogen rocket technology are reported to establish the basic technology and to develop new analytical tools for the evaluation in reusable rocket systems.

  15. Very Good Medicine: Indigenous Humor and Laughter

    ERIC Educational Resources Information Center

    Mala, Cynthia Lindquist

    2016-01-01

    Humor is not only instinctive and a basic human need, but it also is very good medicine. Laughter boosts the immune system, lowers blood pressure, reduces stress hormones, and is linked to healthy functioning organs. [This article was written with Mylo Redwater Smith.

  16. Optimality of the basic colour categories for classification

    PubMed Central

    Griffin, Lewis D

    2005-01-01

    Categorization of colour has been widely studied as a window into human language and cognition, and quite separately has been used pragmatically in image-database retrieval systems. This suggests the hypothesis that the best category system for pragmatic purposes coincides with human categories (i.e. the basic colours). We have tested this hypothesis by assessing the performance of different category systems in a machine-vision task. The task was the identification of the odd-one-out from triples of images obtained using a web-based image-search service. In each triple, two of the images had been retrieved using the same search term, the other a different term. The terms were simple concrete nouns. The results were as follows: (i) the odd-one-out task can be performed better than chance using colour alone; (ii) basic colour categorization performs better than random systems of categories; (iii) a category system that performs better than the basic colours could not be found; and (iv) it is not just the general layout of the basic colours that is important, but also the detail. We conclude that (i) the results support the plausibility of an explanation for the basic colours as a result of a pressure-to-optimality and (ii) the basic colours are good categories for machine vision image-retrieval systems. PMID:16849219

  17. The Rise and Fall of Workplace Basic Skills Programmes: Lessons for Policy and Practice

    ERIC Educational Resources Information Center

    Wolf, Alison; Aspin, Liam; Waite, Edmund; Ananiadou, Katerina

    2010-01-01

    Since the publication of the Moser Report in 1999, improving the basic skills of adults has been a major priority for all of the UK's governments. There has been a particular interest in building up workplace provision, because of the assumed relationship between the basic skills of the employed population and productivity. A longitudinal study…

  18. 21 CFR 341.80 - Labeling of nasal decongestant drug products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... doctor.” (C) “Do not take this product if you have heart disease, high blood pressure, thyroid disease... accompanied by fever, consult a doctor.” (C) “Do not give this product to a child who has heart disease, high... use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or...

  19. 21 CFR 341.80 - Labeling of nasal decongestant drug products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... doctor.” (C) “Do not take this product if you have heart disease, high blood pressure, thyroid disease... accompanied by fever, consult a doctor.” (C) “Do not give this product to a child who has heart disease, high... use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or...

  20. 21 CFR 341.80 - Labeling of nasal decongestant drug products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... doctor.” (C) “Do not take this product if you have heart disease, high blood pressure, thyroid disease... accompanied by fever, consult a doctor.” (C) “Do not give this product to a child who has heart disease, high... use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or...

  1. Enzymatic production of N-acetyl-d-glucosamine from crayfish shell wastes pretreated via high pressure homogenization.

    PubMed

    Wei, Guoguang; Zhang, Alei; Chen, Kequan; Ouyang, Pingkai

    2017-09-01

    This study presents an efficient pretreatment of crayfish shell using high pressure homogenization that enables N-acetyl-d-glucosamine (GlcNAc) production by chitinase. Firstly, the chitinase from Serratia proteamaculans NJ303 was screened for its ability to degrade crayfish shell and produce GlcNAc as the sole product. Secondly, high pressure homogenization, which caused the crayfish shell to adopt a fluffy netted structure that was characterized by Scanning electron microscope (SEM), Fourier transform infrared spectrometer (FT-IR), X-ray diffraction (XRD), was evaluated as the best pretreatment method. In addition, the optimal conditions of high pressure homogenization of crayfish shell were determined to be five cycles at a pressure of 400bar, which achieved a yield of 3.9g/L of GlcNAc from 25g/L of crayfish shell in a batch enzymatic reaction over 1.5h. The results showed high pressure homogenization might be an efficient method for direct utilization of crayfish shell for enzymatic production of GlcNAc. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. The influence of novel compliant floors on balance control in elderly women--A biomechanical study.

    PubMed

    Wright, Alexander D; Laing, Andrew C

    2011-07-01

    Novel compliant floors aim to decrease the risk for fall-related injury by providing substantial force attenuation during the impact phase of falls. Certain models of compliant flooring have been shown to have limited influence on postural sway and successful completion of dynamic balance tasks. However, the effects of these products on balance recovery mechanisms following an externally induced perturbation have yet to be quantified. We used a floor translation paradigm to induce a balance perturbation to thirteen elderly community-dwelling women. Outcome measures included the displacement rates and margins of safety for both the underfoot centre-of-pressure and whole-body centre-of-mass across two novel compliant floors (SmartCell, SofTile), two basic foam surfaces (Firm-Foam, Soft-Foam) and a standard 'Rigid' floor as a control condition. The centre-of-mass and centre-of-pressure margins of safety, and all centre-of-mass displacement rates, were not significantly lower for the two novel compliant flooring systems compared to the control floor. The centre-of-pressure displacement rates were similar to the control floor for the SmartCell floor condition. The majority of the margin of safety and displacement rate variables for the foam floors were significantly lower than the control condition. This study illustrates that the SmartCell and SofTile novel compliant floors have minimal influences on balance and balance control responses following externally induced perturbations in older community-dwelling women, and supports pilot installations of these floors to inform decisions regarding the development of clinical trials. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  3. The influence of novel compliant floors on balance control in elderly women—A biomechanical study

    PubMed Central

    Wright, Alexander D.; Laing, Andrew C.

    2012-01-01

    Novel compliant floors aim to decrease the risk for fall-related injury by providing substantial force attenuation during the impact phase of falls. Certain models of compliant flooring have been shown to have limited influence on postural sway and successful completion of dynamic balance tasks. However, the effects of these products on balance recovery mechanisms following an externally induced perturbation have yet to be quantified. We used a floor translation paradigm to induce a balance perturbation to thirteen elderly community-dwelling women. Outcome measures included the displacement rates and margins of safety for both the underfoot centre-of-pressure and whole-body centre-of-mass across two novel compliant floors (Smart-Cell, SofTile), two basic foam surfaces (Firm-Foam, Soft-Foam) and a standard ‘Rigid’ floor as a control condition. The centre-of-mass and centre-of-pressure margins of safety, and all centre-of-mass displacement rates, were not significantly lower for the two novel compliant flooring systems compared to the control floor. The centre-of-pressure displacement rates were similar to the control floor for the SmartCell floor condition. The majority of the margin of safety and displacement rate variables for the foam floors were significantly lower than the control condition. This study illustrates that the SmartCell and SofTile novel compliant floors have minimal influences on balance and balance control responses following externally induced perturbations in older community-dwelling women, and supports pilot installations of these floors to inform decisions regarding the development of clinical trials. PMID:21545881

  4. Comparative Ecology of H2 Cycling in Organotrophic and Phototrophic Ecosystems

    NASA Technical Reports Server (NTRS)

    Hoehler, Tori M.; Alperin, Marc J.; Albert, Daniel B.; Bebout, Brad M.; Martens, Christopher S.; DesMarais, David J.; DeVincenzi, Don (Technical Monitor)

    2001-01-01

    The simple biochemistry of H2 is critical to a large number of microbial processes, affecting the interaction of organisms with each other and with the environment. The sensitivity of these many processes to H2 can be described quantitatively, at a basic thermodynamic level. This shared dependence on H2 may provide a means for interpreting the ecology and system-level biogeochemistry of widely variant microbial ecosystems on a common (and quantitative) level. Understanding the factors that control H2 itself is a critical prerequisite. Here, we examine two ecosystems that vary widely with respect to H2 cycling. In anoxic, 'organotrophic' sediments from Cape Lookout Bight (North Carolina, USA), H2 partial pressures are strictly maintained at low, steady-state levels by H2-consuming organisms, in a fashion that can be quantitatively predicted by simple thermodynamic calculations. In phototrophic microbial mats from Baja, Mexico, H2 partial pressures are instead controlled by the activity of light-sensitive H2-producing organisms. In consequence, H2 partial pressures within the system fluctuate by orders of magnitude on hour-long time scales. The differences in H2 cycling subsequently impact H2-sensitive microbial processes, such as methanogenesis. For example, the presence of sulfate in the organotrophic system always yielded low levels of H2 that were inhibitory to methanogenesis; however, the elevated levels of H2 in the phototrophic system favored methane production at significant levels, even in the presence of high sulfate concentrations. The myriad of other H2-sensitive microbial processes are expected to exhibit similar behavior.

  5. Apparatus of the Vapor-pressure Measurements for Natural Refrigerants

    NASA Astrophysics Data System (ADS)

    Higuchi, Satoru; Higashi, Yukihiro

    An apparatus for measuring the vapor-pressures was newly designed and constructed in order to make the basic thermodynamic properties for environmentally acceptable refrigerants clear. The temperature of sample fluid was measured with 100Ω platinum resistance thermometer calibrated against ITS-90 using a 25Ω standard platinum resistance thermometer. With respect to the pressure measurement, two kinds of presure transducer were adopted. One is a diaphragm semi-conductor strain pressure transducer with the uncertainty of ±0.09%. This pressure transducer was calibrated against quartz crystal pressure transducer with the uncertainty of ±0.01% after every series of experiments. Another is a quartz crystal pressure transducer with the uncertainty of ±0.01%. A quartz crystal pressure transducer was calibrated against the dead weight pressure gauge and barometer. The vapor-pressures for R-32, R-134a, R-290 (propane), R-600a (iso-butane) and n-pentane were measured in the temperature range between273.15 and 323.15K. As the results of vapor-pressure measurements, the reliability of the experimental apparatus as well as the reproducibility of the experimental data were confirmed. In addition, coefficients of Antoine vapor pressure equation were determined from the experimental data. Normal boiling points for environmentally acceptable refrigerants were also determined with high accuracy.

  6. Enhancement of anaerobic sludge digestion by high-pressure homogenization.

    PubMed

    Zhang, Sheng; Zhang, Panyue; Zhang, Guangming; Fan, Jie; Zhang, Yuxuan

    2012-08-01

    To improve anaerobic sludge digestion efficiency, the effects of high-pressure homogenization (HPH) conditions on the anaerobic sludge digestion were investigated. The VS and TCOD were significantly removed with the anaerobic digestion, and the VS removal and TCOD removal increased with increasing the homogenization pressure and homogenization cycle number; correspondingly, the accumulative biogas production also increased with increasing the homogenization pressure and homogenization cycle number. The optimal homogenization pressure was 50 MPa for one homogenization cycle and 40 MPa for two homogenization cycles. The SCOD of the sludge supernatant significantly increased with increasing the homogenization pressure and homogenization cycle number due to the sludge disintegration. The relationship between the biogas production and the sludge disintegration showed that the accumulative biogas and methane production were mainly enhanced by the sludge disintegration, which accelerated the anaerobic digestion process and improved the methane content in the biogas. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. High pressure inactivation of relevant target microorganisms in poultry meat products and the evaluation of pressure-induced protein denaturation of marinated poultry under different high pressure treatments

    NASA Astrophysics Data System (ADS)

    Schmidgall, Johanna; Hertel, Christian; Bindrich, Ute; Heinz, Volker; Toepfl, Stefan

    2011-03-01

    In this study, the possibility of extending shelf life of marinated poultry meat products by high pressure processing was evaluated. Relevant spoilage and pathogenic strains were selected and used as target microorganisms (MOs) for challenge experiments. Meat and brine were inoculated with MOs and treated at 450 MPa, 4 °C for 3 min. The results of inactivation show a decreasing pressure tolerance in the series Lactobacillus > Arcobacter > Carnobacterium > Bacillus cereus > Brochothrix thermosphacta > Listeria monocytogenes. Leuconostoc gelidum exhibited the highest pressure tolerance in meat. A protective effect of poultry meat was found for L. sakei and L. gelidum. In parallel, the influence of different marinade formulations (pH, carbonates, citrates) on protein structure changes during a pressure treatment was investigated. Addition of sodium carbonate shows a protection against denaturation of myofibrillar proteins and provides a maximum water-holding capacity. Caustic marinades allowed a higher retention of product characteristics than low-pH marinades.

  8. Refractories for high alkali environments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rau, A.W.; Cloer, F.

    1996-12-31

    Information on refractories for high alkali environments is outlined. Information is presented on: product gallery; alkali attack; chemical reactions; basic layout of alkali cup test; criteria for rating alkali cup test samples; and basic layout of physical properties test.

  9. Alternative Fuels Data Center: Hydrogen Basics

    Science.gov Websites

    ; Incentives Hydrogen Basics Hydrogen (H2) is an alternative fuel that can be produced from diverse domestic for domestic production, its fast filling time, and the fuel cell's high efficiency. In fact, a fuel

  10. Study of a Compression-Molding Process for Ultraviolet Light-Emitting Diode Exposure Systems via Finite-Element Analysis

    PubMed Central

    Wu, Kuo-Tsai; Hwang, Sheng-Jye; Lee, Huei-Huang

    2017-01-01

    Although wafer-level camera lenses are a very promising technology, problems such as warpage with time and non-uniform thickness of products still exist. In this study, finite element simulation was performed to simulate the compression molding process for acquiring the pressure distribution on the product on completion of the process and predicting the deformation with respect to the pressure distribution. Results show that the single-gate compression molding process significantly increases the pressure at the center of the product, whereas the multi-gate compressing molding process can effectively distribute the pressure. This study evaluated the non-uniform thickness of product and changes in the process parameters through computer simulations, which could help to improve the compression molding process. PMID:28617315

  11. High-pressure phase transition makes B 4.3 C boron carbide a wide-gap semiconductor

    DOE PAGES

    Hushur, Anwar; Manghnani, Murli H.; Werheit, Helmut; ...

    2016-01-11

    Single-crystal B4.3C boron carbide is investigated concerning the pressure-dependence of optical properties and of Raman-active phonons up to ~70 GPa. The high concentration of structural defects determining the electronic properties of boron carbide at ambient conditions initially decrease and finally vanish with pressure increasing. We obtain this immediately from transparency photos, allowing to estimate the pressure-dependent variation of the absorption edge rapidly increasing around 55 GPa. Glass-like transparency at pressures exceeding 60 GPa indicate that the width of the band exceeds ~3.1 eV thus making boron carbide a wide-gap semiconductor. Furthermore, the spectra of Raman–active phonons indicate a pressure-dependent phasemore » transition in single-crystal natB4.3C boron carbide near 35 GPa., particularly related to structural changes in connection with the C-B-C chains, while the basic icosahedral structure remains largely unaffected.« less

  12. Temperature dependence of thermal pressure for NaCl

    NASA Astrophysics Data System (ADS)

    Singh, Chandra K.; Pande, Brijesh K.; Pandey, Anjani K.

    2018-05-01

    Engineering applications of the materials can be explored upto the desired limit of accuracy with the better knowledge of its mechanical and thermal properties such as ductility, brittleness and Thermal Pressure. For the resistance to fracture (K) and plastic deformation (G) the ratio K/G is treated as an indication of ductile or brittle character of solids. In the present work we have tested the condition of ductility and brittleness with the calculated values of K/G for the NaCl. It is concluded that the nature of NaCl can be predicted upto high temperature simply with the knowledge of its elastic stiffness constant only. Thermoelastic properties of materials at high temperature is directly related to thermal pressure and volume expansion of the materials. An expression for the temperature dependence of thermal pressure is formulated using basic thermodynamic identities. It is observed that thermal pressure ΔPth calculated for NaCl by using Kushwah formulation is in good agreement with the experimental values also the thermal pressure increases with the increase in temperature.

  13. Linkage of the Na,K-ATPase alpha 2 and beta 1 genes with resting and exercise heart rate and blood pressure: cross-sectional and longitudinal observations from the Quebec Family Study.

    PubMed

    Rankinen, T; Pérusse, L; Dériaz, O; Thériault, G; Chagnon, M; Nadeau, A; Bouchard, C

    1999-03-01

    To investigate whether genetic variations in the genes encoding the alpha and beta subunits of the Na,K-ATPase are linked with hemodynamic phenotypes. Cross-sectional data based on 533 subjects (no antihypertensive medication) were obtained from 150 families of phase 2 of the Quebec Family Study, together with longitudinal data from 338 subjects (105 families) who had been measured 12 years earlier in phase 1 of the Quebec Family Study. Restriction fragment length polymorphisms were examined at the alpha 2 (exon 1 and exon 21-22 with BglII) and beta 1 (Msp I and Pvu II) loci of Na,K-ATPase. Hemodynamic phenotypes measured included systolic and diastolic blood pressure, heart rate and rate-pressure product at rest and during low-intensity exercise. Sib-pair analysis revealed relatively strong linkages (P = 0.0003-0.002) between the resting heart rate and rate-pressure product and the alpha 2 exon 21-22 marker and alpha 2 haplotype. Moreover, the alpha 2 exon 21-22 marker showed suggestive linkages (P = 0.01 to 0.043) with resting systolic blood pressure and exercise diastolic blood pressure, heart rate and rate-pressure product, and the alpha 2 haplotype with exercise diastolic blood pressure and rate-pressure product and the 12-year change in resting systolic blood pressure (P = 0.03 to 0.05). Both the beta 1 Msp I marker and the beta 1 haplotype were linked with the resting rate-pressure product (P = 0.007 and 0.003, respectively), and all beta 1 markers showed linkage with the change in resting systolic blood pressure (P = 0.00005 to 0.024). In men, there was a significant (P = 0.01) interaction between the alpha 2 exon 21-22 genotype and the postglucose plasma insulin level with regard to resting systolic blood pressure. These data suggest that the alpha 2 and beta 1 genes of Na,K-ATPase contribute to the regulation of hemodynamic phenotypes in healthy subjects.

  14. Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions.

    PubMed

    Needham, Charles E; Ritzel, David; Rule, Gregory T; Wiri, Suthee; Young, Leanne

    2015-01-01

    Over the past several years, we have noticed an increase in the number of blast injury studies published in peer-reviewed biomedical journals that have utilized improperly conceived experiments. Data from these studies will lead to false conclusions and more confusion than advancement in the understanding of blast injury, particularly blast neurotrauma. Computational methods to properly characterize the blast environment have been available for decades. These methods, combined with a basic understanding of blast wave phenomena, enable researchers to extract useful information from well-documented experiments. This basic understanding must include the differences and interrelationships of static pressure, dynamic pressure, reflected pressure, and total or stagnation pressure in transient shockwave flows, how they relate to loading of objects, and how they are properly measured. However, it is critical that the research community effectively overcomes the confusion that has been compounded by a misunderstanding of the differences between the loading produced by a free field explosive blast and loading produced by a conventional shock tube. The principles of blast scaling have been well established for decades and when properly applied will do much to repair these problems. This paper provides guidance regarding proper experimental methods and offers insights into the implications of improperly designed and executed tests. Through application of computational methods, useful data can be extracted from well-documented historical tests, and future work can be conducted in a way to maximize the effectiveness and use of valuable biological test data.

  15. Refining Reproductive Parameters for Modelling Sustainability and Extinction in Hunted Primate Populations in the Amazon

    PubMed Central

    Bowler, Mark; Anderson, Matt; Montes, Daniel; Pérez, Pedro; Mayor, Pedro

    2014-01-01

    Primates are frequently hunted in Amazonia. Assessing the sustainability of hunting is essential to conservation planning. The most-used sustainability model, the ‘Production Model’, and more recent spatial models, rely on basic reproductive parameters for accuracy. These parameters are often crudely estimated. To date, parameters used for the Amazon’s most-hunted primate, the woolly monkey (Lagothrix spp.), come from captive populations in the 1960s, when captive births were rare. Furthermore, woolly monkeys have since been split into five species. We provide reproductive parameters calculated by examining the reproductive organs of female Poeppig’s woolly monkeys (Lagothrix poeppigii), collected by hunters as part of their normal subsistence activity. Production was 0.48–0.54 young per female per year, and an interbirth interval of 22.3 to 25.2 months, similar to parameters from captive populations. However, breeding was seasonal, which imposes limits on the maximum reproductive rate attainable. We recommend the use of spatial models over the Production Model, since they are less sensitive to error in estimated reproductive rates. Further refinements to reproductive parameters are needed for most primate taxa. Methods like ours verify the suitability of captive reproductive rates for sustainability analysis and population modelling for populations under differing conditions of hunting pressure and seasonality. Without such research, population modelling is based largely on guesswork. PMID:24714614

  16. Artificial intelligence approaches to software engineering

    NASA Technical Reports Server (NTRS)

    Johannes, James D.; Macdonald, James R.

    1988-01-01

    Artificial intelligence approaches to software engineering are examined. The software development life cycle is a sequence of not so well-defined phases. Improved techniques for developing systems have been formulated over the past 15 years, but pressure continues to attempt to reduce current costs. Software development technology seems to be standing still. The primary objective of the knowledge-based approach to software development presented in this paper is to avoid problem areas that lead to schedule slippages, cost overruns, or software products that fall short of their desired goals. Identifying and resolving software problems early, often in the phase in which they first occur, has been shown to contribute significantly to reducing risks in software development. Software development is not a mechanical process but a basic human activity. It requires clear thinking, work, and rework to be successful. The artificial intelligence approaches to software engineering presented support the software development life cycle through the use of software development techniques and methodologies in terms of changing current practices and methods. These should be replaced by better techniques that that improve the process of of software development and the quality of the resulting products. The software development process can be structured into well-defined steps, of which the interfaces are standardized, supported and checked by automated procedures that provide error detection, production of the documentation and ultimately support the actual design of complex programs.

  17. Identification of the specified impurities of silver sulfadiazine using a screening of degradation products in different stress physico-chemical media.

    PubMed

    Cioroiu, Bogdan I; Lazar, Mihai I; Bello-López, Miguel A; Fernandez-Torres, Rut

    2013-11-15

    Determination of silver sulfadiazine degradation products in several stress media was carried out by high pressure liquid chromatography (HPLC) with diode array detector (DAD) and hybrid mass spectrometer triple quadrupole-linear trap. The optimal chromatographic method used a Hypercarb column with a stationary phase 100% carbon, a mobile phase composed by a mixture 45:55 formic acid 1% solution and acetonitrile and detection at 275 nm. Structure elucidation was carried out on the mass spectrometry system using same chromatographic conditions and based on MS/MS techniques. Under these conditions up to 9 possible impurities were demonstrated to be degradation products respecting silver sulfadiazine evolution under different stress conditions: temperature, acid, basic, oxidation, reduction and catalyzed photodegradation. Sulfacetamide, sulfanilic acid (4-aminobenzenesulfonic acid), aniline, pyrimidin-2-amine, 4-aminobenzenesulfonamide, 4-methylidenesulfanilaniline, 4-aminophenol, 4-amino-n-methyl benzenesulfonamide and benzenesulfonic acid were identified by mass spectrometry in order to cover the possible degradation paths of silver sulfadiazine. Kinetics were also evaluated to obtain the prediction of shelf life of the substance. The linearity domain for the method was between 0.0005 mg/ml and 0.25mg/ml for each compound. Recovery factors in accuracy determination were between 95 and 105% relative to target concentrations of silver sulfadiazine and the quantitation limit was 0.00025 mg/ml. Copyright © 2013 Elsevier B.V. All rights reserved.

  18. Mitigating an increase of specific power consumption in a cryogenic air separation unit at reduced oxygen production

    NASA Astrophysics Data System (ADS)

    Singla, Rohit; Chowdhury, Kanchan

    2017-02-01

    Specific power consumed in a Linde double column air separation unit (ASU) increases as the quantity of oxygen produced at a given purity is decreased due to the changes of system requirement or market demand. As the plant operates in part load condition, the specific power consumption (SPC) increases as the total power consumption remains the same. In order to mitigate the increase of SPC at lower oxygen production, the operating pressure of high pressure column (HPC) can be lowered by extending the low pressure column (LPC) by a few trays and adding a second reboiler. As the duty of second reboiler in LPC is increased, the recovery of oxygen decreases with a lowering of the HPC pressure. This results in mitigation of the increase of SPC of the plant. A Medium pressure ASU with dual reboiler that produces pressurised gaseous and liquid products of oxygen and nitrogen is simulated in Aspen Hysys 8.6®, a commercial process simulator to determine SPC at varying oxygen production. The effects of reduced pressure of air feed into the cold box on the size of heat exchangers (HX) are analysed. Operation strategy to obtain various oxygen production rates at varying demand is also proposed.

  19. Influence of Basicity on High-Chromium Vanadium-Titanium Magnetite Sinter Properties, Productivity, and Mineralogy

    NASA Astrophysics Data System (ADS)

    Zhou, Mi; Yang, Songtao; Jiang, Tao; Xue, Xiangxin

    2015-05-01

    The effect of basicity on high-chromium vanadium-titanium magnetite (V-Ti-Cr) sintering was studied via sintering pot tests. The sinter rate, yield, and productivity were calculated before determining sinter strength (TI) and reduction degradation index (RDI). Furthermore, the effect of basicity on V-Ti-Cr sinter mineralogy was clarified using metallographic microscopy, x-ray diffraction, and scanning electron microscopy-energy-dispersive x-ray spectroscopy. The results indicate that increasing basicity quickly increases the sintering rate from 25.4 mm min-1 to 28.9 mm min-1, yield from 75.3% to 87.2%, TI from 55.4% to 64.8%, and productivity from 1.83 t (m2 h)-1 to 1.94 t (m2 h)-1 before experiencing a slight drop. The V-Ti-Cr sinter shows complex mineral composition, with main mineral phases such as magnetite, hematite, silicate (dicalcium silicate, Ca-Fe olivine, glass), calcium and aluminum silico-ferrite (SFCA/SFCAI) and perovskite. Perovskite is notable because it lowers the V-Ti sinter strength and RDI. The well intergrowths between magnetite and SFCA/SFCAI, and the decrease in perovskite and secondary skeletal hematite are the key for improving TI and RDI. Finally, a comprehensive index was calculated, and the optimal V-Ti-Cr sinter basicity also for industrial application was 2.55.

  20. Cathepsin H Functions as an Aminopeptidase in Secretory Vesicles for Production of Enkephalin and Galanin Peptide Neurotransmitters

    PubMed Central

    Lu, W. Douglas; Funkelstein, Lydiane; Toneff, Thomas; Reinheckel, Thomas; Peters, Christoph; Hook, Vivian

    2012-01-01

    Peptide neurotransmitters function as key intercellular signaling molecules in the nervous system. These peptides are generated in secretory vesicles from proneuropeptides by proteolytic processing at dibasic residues, followed by removal of N- and/or C-terminal basic residues to form active peptides. Enkephalin biosynthesis from proenkephalin utilizes the cysteine protease cathepsin L and the subtilisin-like prohormone convertase 2 (PC2). Cathepsin L generates peptide intermediates with N-terminal basic residue extensions, which must be removed by an aminopeptidase. In this study, we identified cathepsin H as an aminopeptidase in secretory vesicles that produces (Met)enkephalin (ME) by sequential removal of basic residues from KR-ME and KK-ME, supported by in vivo knockout of the cathepsin H gene. Localization of cathepsin H in secretory vesicles was demonstrated by immunoelectron microscopy and confocal immunofluorescence microscopy. Purified human cathepsin H sequentially removes N-terminal basic residues to generate ME, with peptide products characterized by nano-LC-MS/MS tandem mass spectrometry. Cathepsin H shows highest activities for cleaving N-terminal basic residues (Arg and Lys) among amino acid fluorogenic substrates. Notably, knockout of the cathepsin H gene results in reduction of ME in mouse brain. Cathepsin H deficient mice also show a substantial decrease in galanin peptide neurotransmitter levels in brain. These results illustrate a role for cathepsin H as an aminopeptidase for enkephalin and galanin peptide neurotransmitter production. PMID:22582844

  1. Medium- and high-pressure gauges and transducers produced by laser welding technology

    NASA Astrophysics Data System (ADS)

    Daurelio, Giuseppe; Nenci, Fabio; Cinquepalmi, Massimo; Chita, Giuseppe

    1998-07-01

    Industrial manufacturers produce many types of pressure gauges and transducers according to the applications, for gas or liquid, for high-medium and low pressure ranges. Nowadays the current production technology generally prefers to weld by micro TIG source the metallic corrugated membranes to the gauge or transducer bodies for the products, operating on the low pressure or medium pressure ranges. For the other ones, operating to high pressure range, generally the two components of the transducers are both threaded only and threaded and then circularly welded by micro TIG for the other higher range, till to 1000 bar. In this work the products, operating on the approximately equals 30 divided by 200 bar, are considered. These, when assembled on industrial plants, as an outcome of a non-correct operating sequence, give a 'shifted' electrical signal. This is due to a shift of the 'zero electrical signal' that unbalances the electrical bridge - thin layer sensor - that is the sensitive part of the product. Moreover, for the same problem, often some mechanical settlings of the transducer happen during the first pressure semi-components, with an increasing of the product manufacturing costs. In light of all this, the above referred, in this work the whole transducer has been re-designed according to the specific laser welding technology requirements. On the new product no threaded parts exist but only a circular laser welding with a full penetration depth about 2.5 divided by 3 mm high. Three different alloys have been tested according to the applications and the mechanical properties requested to the transducer. By using a 1.5 KW CO2 laser system many different working parameters have been evaluated for correlating laser parameters to the penetration depths, crown wides, interaction laser-materia times, mechanical and metallurgical properties. Moreover during the laser welding process the measurements of the maximum temperature, reached by the transducer top, has been read and recorded. At least some transducers, before the usual destructive testings, have been undertaken to many pressure test cycles to verify any pressure drops, the transducer sealing and the total quality of the new product.

  2. Intake of dietary salt and drinking water: Implications for the development of age-related macular degeneration

    PubMed Central

    Hollborn, Margrit; Kohen, Leon; Wiedemann, Peter

    2016-01-01

    Purpose Systemic hypertension is a risk factor of age-related retinal diseases such as diabetic retinopathy and age-related macular degeneration. High intake of dietary salt and low intake of water increase extracellular osmolality resulting in hypertension, in particular in salt-sensitive individuals. This review summarizes the present knowledge regarding the impact of salt and water intake on the regulation of blood pressure, retinal function, and the development of age-related retinal diseases. Methods A literature search of the Medline database and a summary of recent studies that used human RPE cells. Results The salt sensitivity of the blood pressure and plasma osmolality increase with age, and body water deficits are common in older individuals. High plasma osmolality has adverse effects in the retina. In RPE cells, high osmolality induces expression and secretion of angiogenic factors, such as vascular endothelial growth factor (VEGF), placental growth factor, and basic fibroblast growth factor, and expression of aquaporin-5, a water channel implicated in transepithelial water transport. The transcriptional activities of hypoxia-inducible factor-1 (HIF-1) and nuclear factor of activated T cell 5 (NFAT5) are critical for the production of VEGF in response to salt-induced osmotic stress. Salt-induced osmotic stress also induces priming of the NLRP3 inflammasome and activates inflammatory enzymes in RPE cells. Conclusions Raised plasma osmolality may aggravate age-related retinal diseases by stimulation of local inflammation and angiogenic factor production in the RPE. Alterations in salt and water consumption, and of minerals that stimulate renal salt excretion, may offer nutritional approaches to prevent age-related retinal disorders, in particular in salt-sensitive individuals and individuals who show signs of body dehydration. PMID:28031693

  3. Intake of dietary salt and drinking water: Implications for the development of age-related macular degeneration.

    PubMed

    Bringmann, Andreas; Hollborn, Margrit; Kohen, Leon; Wiedemann, Peter

    2016-01-01

    Systemic hypertension is a risk factor of age-related retinal diseases such as diabetic retinopathy and age-related macular degeneration. High intake of dietary salt and low intake of water increase extracellular osmolality resulting in hypertension, in particular in salt-sensitive individuals. This review summarizes the present knowledge regarding the impact of salt and water intake on the regulation of blood pressure, retinal function, and the development of age-related retinal diseases. A literature search of the Medline database and a summary of recent studies that used human RPE cells. The salt sensitivity of the blood pressure and plasma osmolality increase with age, and body water deficits are common in older individuals. High plasma osmolality has adverse effects in the retina. In RPE cells, high osmolality induces expression and secretion of angiogenic factors, such as vascular endothelial growth factor (VEGF), placental growth factor, and basic fibroblast growth factor, and expression of aquaporin-5, a water channel implicated in transepithelial water transport. The transcriptional activities of hypoxia-inducible factor-1 (HIF-1) and nuclear factor of activated T cell 5 (NFAT5) are critical for the production of VEGF in response to salt-induced osmotic stress. Salt-induced osmotic stress also induces priming of the NLRP3 inflammasome and activates inflammatory enzymes in RPE cells. Raised plasma osmolality may aggravate age-related retinal diseases by stimulation of local inflammation and angiogenic factor production in the RPE. Alterations in salt and water consumption, and of minerals that stimulate renal salt excretion, may offer nutritional approaches to prevent age-related retinal disorders, in particular in salt-sensitive individuals and individuals who show signs of body dehydration.

  4. Basic principles for measurement of intramuscular pressure

    NASA Technical Reports Server (NTRS)

    Hargens, A. R.; Ballard, R. E.

    1995-01-01

    We review historical and methodological approaches to measurements of intramuscular pressure (IMP) in humans. These techniques provide valuable measures of muscle tone and activity as well as diagnostic criteria for evaluation of exertional compartment syndrome. Although the wick and catheter techniques provide accurate measurements of IMP at rest, their value for exercise studies and diagnosis of exertional compartment syndrome is limited because of low frequency response and hydrostatic (static and inertial) pressure artifacts. Presently, most information on diagnosis of exertional compartment syndromes during dynamic exercise is available using the Myopress catheter. However, future research and clinical diagnosis using IMP can be optimized by the use of a miniature transducer-tipped catheter such as the Millar Mikro-tip.

  5. The NASA Langley Laminar-Flow-Control Experiment on a Swept Supercritical Airfoil: Basic Results for Slotted Configuration

    NASA Technical Reports Server (NTRS)

    Harris, Charles D.; Brooks, Cuyler W., Jr.; Clukey, Patricia G.; Stack, John P.

    1989-01-01

    The effects of Mach number and Reynolds number on the experimental surface pressure distributions and transition patterns for a large chord, swept supercritical airfoil incorporating an active Laminar Flow Control suction system with spanwise slots are presented. The experiment was conducted in the Langley 8 foot Transonic Pressure Tunnel. Also included is a discussion of the influence of model/tunnel liner interactions on the airfoil pressure distribution. Mach number was varied from 0.40 to 0.82 at two chord Reynolds numbers, 10 and 20 x 1,000,000, and Reynolds number was varied from 10 to 20 x 1,000,000 at the design Mach number.

  6. Meridionally propagating interannual-to-interdecadal variability in a linear ocean-atmosphere model

    NASA Technical Reports Server (NTRS)

    Mehta, Vikram M.

    1992-01-01

    Meridional oscillation modes in a global, primitive-equation coupled ocean-atmosphere model have been analyzed in order to determine whether they contain such meridionally propagating modes as surface-pressure perturbations with years-to-decades oscillation periods. A two-layer global ocean model and a two-level global atmosphere model were then formulated. For realistic parameter values and basic states, meridional modes oscillating at periods of several years to several decades are noted to be present in the coupled ocean-atmosphere model; the oscillation periods, travel times, and meridional structures of surface pressure perturbations in one of the modes are found to be comparable to the corresponding characteristics of observed sea-level pressure perturbations.

  7. Wind tunnel tests for wind pressure distribution on gable roof buildings.

    PubMed

    Jing, Xiao-kun; Li, Yuan-qi

    2013-01-01

    Gable roof buildings are widely used in industrial buildings. Based on wind tunnel tests with rigid models, wind pressure distributions on gable roof buildings with different aspect ratios were measured simultaneously. Some characteristics of the measured wind pressure field on the surfaces of the models were analyzed, including mean wind pressure, fluctuating wind pressure, peak negative wind pressure, and characteristics of proper orthogonal decomposition results of the measured wind pressure field. The results show that extremely high local suctions often occur in the leading edges of longitudinal wall and windward roof, roof corner, and roof ridge which are the severe damaged locations under strong wind. The aspect ratio of building has a certain effect on the mean wind pressure coefficients, and the effect relates to wind attack angle. Compared with experimental results, the region division of roof corner and roof ridge from AIJ2004 is more reasonable than those from CECS102:2002 and MBMA2006.The contributions of the first several eigenvectors to the overall wind pressure distributions become much bigger. The investigation can offer some basic understanding for estimating wind load distribution on gable roof buildings and facilitate wind-resistant design of cladding components and their connections considering wind load path.

  8. Dynamic characteristic investigation on the fuel pressure of diesel engines electronic in-line pump system

    NASA Astrophysics Data System (ADS)

    Liu, You; Yuan, Zhi-Guo; Fan, Li-Yun; Tian, Bin-Qi

    2010-12-01

    The electronic in-line pump (EIP) is a complex system consisting of mechanical, hydraulic, and electromagnetic parts. Experimental study showed that the fuel pressure of the plunger and the fuel drainage of the pressure system after fuel injection could result in fuel pressure fluctuation in the low pressure system. Such fluctuation exhibited pulsating cycle fluctuation as the amplitude rose with the increase of the injection pulse width. The time domain analysis found that the pressure time history curve and injection cylinders corresponded with a one-to-one relationship. By frequency domain analysis, the result was that with the increase of the working cylinder number, the high frequency amplitude gradually increased and the basic frequency amplitude gradually decreased. The conclusion was that through wavelet transformation, the low pressure signal simultaneously moved towards low frequency as the high frequency of the wavelet transformation signal with the working cylinder number increased. Lastly, by using the numerical model, the study investigated the simulation research concerning the relationship of the fluctuation dynamic characteristic in the low pressure system and the fuel injection characteristic of the high pressure system, completing the conclusions obtained by the experimental study.

  9. Distortion product otoacoustic emissions upon ear canal pressurization.

    PubMed

    Zebian, Makram; Schirkonyer, Volker; Hensel, Johannes; Vollbort, Sven; Fedtke, Thomas; Janssen, Thomas

    2013-04-01

    The purpose of this study was to quantify the change in distortion product otoacoustic emission (DPOAE) level upon ear canal pressurization. DPOAEs were measured on 12 normal-hearing human subjects for ear canal static pressures between -200 and +200 daPa in (50 ± 5) daPa steps. A clear dependence of DPOAE levels on the pressure was observed, with levels being highest at the maximum compliance of the middle ear, and decreasing on average by 2.3 dB per 50 daPa for lower and higher pressures. Ear canal pressurization can serve as a tool for improving the detectability of DPOAEs in the case of middle-ear dysfunction.

  10. Investigation of Pressure Surges in Aircraft Hydraulic Systems

    DTIC Science & Technology

    1952-03-01

    RESTRICTED Figure 2 TEST APPARATUS FOR CLOSED-END TUBE SYSTEM TESTS , r WADC TR52-37 10 SECURITY INFORMATION-RESTRICTED SECURITY INFORMATION -R ESTR ICTED...simplified circuitto--decrease the labor involved in circuit solutions by manual calculation. The circuit developed for the basic accumulator, valve

  11. Using Discrepant Events to Inspire Writing.

    ERIC Educational Resources Information Center

    Ruck, Carolyn; And Others

    1991-01-01

    Demonstrations that can be used to lead students to wonder and write about basic scientific principles are presented. Each demonstration includes the concept demonstrated, a list of materials, and procedures. Concepts include density and temperature of liquids, contracting matter with heat, atmospheric pressure, dramatic color changes, fireproof…

  12. Is That Boiler Ready To Blow?

    ERIC Educational Resources Information Center

    Robinson, Glenn S.; Trombley, Robert E.

    2001-01-01

    Discusses implementation of a thorough assessment program to determine the condition of boilers, pressure vessels and other plant equipment to determine the feasibility of part or entire system replacement. Assessment basics are examined as are tips for selecting the right inspection and engineering contractor for assessments. (GR)

  13. System International d'Unites: Metric Measurement in Water Resources Engineering.

    ERIC Educational Resources Information Center

    Klingeman, Peter C.

    This pamphlet gives definitions and symbols for the basic and derived metric units, prefixes, and conversion factors for units frequently used in water resources. Included are conversion factors for units of area, work, heat, power, pressure, viscosity, flow rate, and others. (BB)

  14. An Online Prediction Platform to Support the Environmental Sciences (American Chemical Society)

    EPA Science Inventory

    Historical QSAR models are currently utilized across a broad range of applications within the U.S. Environmental Protection Agency (EPA). These models predict basic physicochemical properties (e.g., logP, aqueous solubility, vapor pressure), which are then incorporated into expo...

  15. Changing Families Changing Schools.

    ERIC Educational Resources Information Center

    Evans, Robert

    The decline in civility, social responsibility, and institutional affiliation challenges the nature of schooling. Child development in the 1990s family is under pressure from changes that deny children the three basic essentials (nurture, structure, and latitude) for psychological health, effective learning, and civility, and that require children…

  16. Negative Pressure Wound Therapy Followed by Basic Fibroblast Growth Factor Spray as a Recovery Technique in Partial Necrosis of Distally Based Sural Flap for Calcaneal Osteomyelitis: A Case Report.

    PubMed

    Mikami, Taro; Kaida, Eriko; Yabuki, Yuichiro; Kitamura, Sho; Kokubo, Ken'ichi; Maegawa, Jiro

    2018-03-28

    The distally based sural flap is regarded as the first choice for reconstruction in the distal part of the lower leg because the flap is easy to raise, reliable in its blood supply, and prone to only a few complications. Limited data have investigated the details of treatment in cases of failure of distally based sural flaps. We report a case of calcaneal osteomyelitis in which a successful outcome was finally obtained with a partially necrosed, distally based sural flap using negative pressure wound therapy with basic fibroblast growth factor spray. The 2-year follow-up examination was uneventful. Moreover, the patient was able to walk freely with an ankle-foot orthosis in her house. This technique can be considered as a useful and effective option to recover unfavorable results of distally based sural flaps. Copyright © 2017 The American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  17. Melt segregation from partially molten source regions - The importance of melt density and source region size

    NASA Technical Reports Server (NTRS)

    Stolper, E.; Hager, B. H.; Walker, D.; Hays, J. F.

    1981-01-01

    An investigation is conducted regarding the changes expected in the density contrast between basic melts and peridotites with increasing pressure using the limited data available on the compressibilities of silicate melts and data on the densities of mantle minerals. It is concluded that since compressibilities of silicate melts are about an order of magnitude greater than those of mantle minerals, the density contrast between basic melts and mantle minerals must diminish significantly with increasing pressure. An earlier analysis regarding the migration of liquid in partially molten source regions conducted by Walker et al. (1978) is extended, giving particular attention to the influence of the diminished density contrast between melt and residual crystals with increasing source region depth and to the influence of source region size. This analysis leads to several generalizations concerning the factors influencing the depths at which magmas will segregate from their source regions and the degrees of partial melting that can be achieved in these source regions before melt segregation occurs.

  18. Weed Control Strategies for Organic Peanut Production and Transition: A Lesson in Basic Agronomy

    USDA-ARS?s Scientific Manuscript database

    Weed control in organic peanut production is difficult and costly. The only production inputs that consistently improved weed management in organic peanut production were modified production practices and intense cultivation with a tine weeder. Research trials evaluated row patterns, seeding rates...

  19. Understanding MRI: basic MR physics for physicians.

    PubMed

    Currie, Stuart; Hoggard, Nigel; Craven, Ian J; Hadjivassiliou, Marios; Wilkinson, Iain D

    2013-04-01

    More frequently hospital clinicians are reviewing images from MR studies of their patients before seeking formal radiological opinion. This practice is driven by a multitude of factors, including an increased demand placed on hospital services, the wide availability of the picture archiving and communication system, time pressures for patient treatment (eg, in the management of acute stroke) and an inherent desire for the clinician to learn. Knowledge of the basic physical principles behind MRI is essential for correct image interpretation. This article, written for the general hospital physician, describes the basic physics of MRI taking into account the machinery, contrast weighting, spin- and gradient-echo techniques and pertinent safety issues. Examples provided are primarily referenced to neuroradiology reflecting the subspecialty for which MR currently has the greatest clinical application.

  20. Sodium sulfate - Deposition and dissolution of silica

    NASA Technical Reports Server (NTRS)

    Jacobson, Nathan S.

    1989-01-01

    The hot-corrosion process for SiO2-protected materials involves deposition of Na2SO4 and dissolution of the protective SiO2 scale. Dew points for Na2SO4 deposition are calculated as a function of pressure, sodium content, and sulfur content. Expected dissolution regimes for SiO2 are calculated as a function of Na2SO4 basicity. Controlled-condition burner-rig tests on quartz verify some of these predicted dissolution regimes. The basicity of Na2SO4 is not always a simple function of P(SO3). Electrochemical measurements of an (Na2O) show that carbon creates basic conditions in Na2SO4, which explains the extensive corrosion of SiO2-protected materials containing carbon, such as SiC.

  1. Influence of headspace pressure on methane production in Biochemical Methane Potential (BMP) tests.

    PubMed

    Valero, David; Montes, Jesús A; Rico, José Luis; Rico, Carlos

    2016-02-01

    The biochemical methane potential test is the most commonly applied method to determine methane production from organic wastes. One of the parameters measured is the volume of biogas produced which can be determined manometrically by keeping the volume constant and measuring increases in pressure. In the present study, the effect of pressure accumulation in the headspace of the reactors has been studied. Triplicate batch trials employing cocoa shell, waste coffee grounds and dairy manure as substrates have been performed under two headspace pressure conditions. The results obtained in the study showed that headspace overpressures higher than 600mbar affected methane production for waste coffee grounds. On the contrary, headspace overpressures within a range of 600-1000mbar did not affect methane production for cocoa shell and dairy manure. With the analyses performed in the present work it has not been possible to determine the reasons for the lower methane yield value obtained for the waste coffee grounds under high headspace pressures. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Uniform pressures in gas fields (in Spanish)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bravo, G.

    1966-08-01

    Throughout the huge Reynosa Field, petroleos Mexicanos (Pemex) is equalizing gas-well pressures to reduce the expense of gas-compressing equipment. This solution was proposed by the Department of Gas and Gasoline. Tests were taken on 4 specially selected wells. The results show production to be much less than the potential; by equalizing pressure, production is increased at less cost.

  3. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of air from a retort before the start of process timing. (x) Water activity. The ratio of the water vapor pressure of the product to the vapor pressure of pure water at the same temperature. ... throughout the entire thermal process. (d) Canned product. A poultry food product with a water activity above...

  4. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... of air from a retort before the start of process timing. (x) Water activity. The ratio of the water vapor pressure of the product to the vapor pressure of pure water at the same temperature. ... throughout the entire thermal process. (d) Canned product. A poultry food product with a water activity above...

  5. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... of air from a retort before the start of process timing. (x) Water activity. The ratio of the water vapor pressure of the product to the vapor pressure of pure water at the same temperature. ... throughout the entire thermal process. (d) Canned product. A poultry food product with a water activity above...

  6. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of air from a retort before the start of process timing. (x) Water activity. The ratio of the water vapor pressure of the product to the vapor pressure of pure water at the same temperature. ... throughout the entire thermal process. (d) Canned product. A poultry food product with a water activity above...

  7. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of air from a retort before the start of process timing. (x) Water activity. The ratio of the water vapor pressure of the product to the vapor pressure of pure water at the same temperature. ... throughout the entire thermal process. (d) Canned product. A poultry food product with a water activity above...

  8. Basic language comprehension and production in >100,000 young children from sixteen developing nations

    PubMed Central

    BORNSTEIN, MARC H.; HENDRICKS, CHARLENE

    2013-01-01

    Using the Multiple Indicator Cluster Survey, language comprehension and production were compared in a sample of 101,250 children aged 2;00 to 9;11 and a focus subsample of 38,845 children aged 2;00 to 4;11 from sixteen under-researched developing nations. In the whole sample, comprehension slightly exceeded production; correlations between comprehension and production by country were positive and significant, but varied in size, and the average correlation was positive, significant, and small to medium. Mean comprehension and production varied with child age, reaching an asymptote at 5;00, and correlations between comprehension and production by age were positive, significant, and similar at each age. In the focus subsample, comprehension exceeded production; correlations between comprehension and production by country were positive and significant, but varied in size, and the average correlation was positive, significant, and medium in size. Children in countries with lower standards of living were less likely to demonstrate basic language comprehension or production. PMID:22129486

  9. The evaluation of the optimization design and application effect of same-well-injection-production technique’s injection-production circulatory system

    NASA Astrophysics Data System (ADS)

    Guoxing, Zheng; Minghu, Jiang; Hongliang, Gong; Nannan, Zhang; Jianguang, Wei

    2018-02-01

    According to basic principles of combining series of strata and demands of same-well injection-production technique, the optimization designing method of same-well injection-production technique’s injection-production circulatory system is given. Based on oil-water two-phase model with condition of arbitrarily well network, a dynamic forecast method for the application of same-well injection-production reservoir is established with considering the demands and capacity of same-well injection-production technique, sample wells are selected to launch the forecast evaluation and analysis of same-well injection-production reservoir application’s effect. Results show: single-test-well composite water cut decreases by 4.7% and test-well-group composite water cut decreases by 1.56% under the condition of basically invariant ground water injection rate. The method provides theoretical support for the proof of same-well injection-production technique’s reservoir development improving effect and further tests.

  10. Modeling conductive heat transfer during high-pressure thawing processes: determination of latent heat as a function of pressure.

    PubMed

    Denys, S; Van Loey, A M; Hendrickx, M E

    2000-01-01

    A numerical heat transfer model for predicting product temperature profiles during high-pressure thawing processes was recently proposed by the authors. In the present work, the predictive capacity of the model was considerably improved by taking into account the pressure dependence of the latent heat of the product that was used (Tylose). The effect of pressure on the latent heat of Tylose was experimentally determined by a series of freezing experiments conducted at different pressure levels. By combining a numerical heat transfer model for freezing processes with a least sum of squares optimization procedure, the corresponding latent heat at each pressure level was estimated, and the obtained pressure relation was incorporated in the original high-pressure thawing model. Excellent agreement with the experimental temperature profiles for both high-pressure freezing and thawing was observed.

  11. Use of hydrostatic pressure for modulation of protein chemical modification and enzymatic selectivity.

    PubMed

    Makarov, Alexey A; Helmy, Roy; Joyce, Leo; Reibarkh, Mikhail; Maust, Mathew; Ren, Sumei; Mergelsberg, Ingrid; Welch, Christopher J

    2016-05-11

    Using hydrostatic pressure to induce protein conformational changes can be a powerful tool for altering the availability of protein reactive sites and for changing the selectivity of enzymatic reactions. Using a pressure apparatus, it has been demonstrated that hydrostatic pressure can be used to modulate the reactivity of lysine residues of the protein ubiquitin with a water-soluble amine-specific homobifunctional coupling agent. Fewer reactive lysine residues were observed when the reaction was carried out under elevated pressure of 3 kbar, consistent with a pressure-induced conformational change of ubiquitin that results in fewer exposed lysine residues. Additionally, modulation of the stereoselectivity of an enzymatic transamination reaction was observed at elevated hydrostatic pressure. In one case, the minor diasteromeric product formed at atmospheric pressure became the major product at elevated pressure. Such pressure-induced alterations of protein reactivity may provide an important new tool for enzymatic reactions and the chemical modification of proteins.

  12. A LabVIEW model incorporating an open-loop arterial impedance and a closed-loop circulatory system.

    PubMed

    Cole, R T; Lucas, C L; Cascio, W E; Johnson, T A

    2005-11-01

    While numerous computer models exist for the circulatory system, many are limited in scope, contain unwanted features or incorporate complex components specific to unique experimental situations. Our purpose was to develop a basic, yet multifaceted, computer model of the left heart and systemic circulation in LabVIEW having universal appeal without sacrificing crucial physiologic features. The program we developed employs Windkessel-type impedance models in several open-loop configurations and a closed-loop model coupling a lumped impedance and ventricular pressure source. The open-loop impedance models demonstrate afterload effects on arbitrary aortic pressure/flow inputs. The closed-loop model catalogs the major circulatory waveforms with changes in afterload, preload, and left heart properties. Our model provides an avenue for expanding the use of the ventricular equations through closed-loop coupling that includes a basic coronary circuit. Tested values used for the afterload components and the effects of afterload parameter changes on various waveforms are consistent with published data. We conclude that this model offers the ability to alter several circulatory factors and digitally catalog the most salient features of the pressure/flow waveforms employing a user-friendly platform. These features make the model a useful instructional tool for students as well as a simple experimental tool for cardiovascular research.

  13. Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations.

    PubMed

    He, Chiyang; Zhu, Zaifang; Gu, Congying; Lu, Joann; Liu, Shaorong

    2012-03-02

    Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet and outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (∼3100 psi). We further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Measurement of the resistivity of porous materials with an alternating air-flow method.

    PubMed

    Dragonetti, Raffaele; Ianniello, Carmine; Romano, Rosario A

    2011-02-01

    Air-flow resistivity is a main parameter governing the acoustic behavior of porous materials for sound absorption. The international standard ISO 9053 specifies two different methods to measure the air-flow resistivity, namely a steady-state air-flow method and an alternating air-flow method. The latter is realized by the measurement of the sound pressure at 2 Hz in a small rigid volume closed partially by the test sample. This cavity is excited with a known volume-velocity sound source implemented often with a motor-driven piston oscillating with prescribed area and displacement magnitude. Measurements at 2 Hz require special instrumentation and care. The authors suggest an alternating air-flow method based on the ratio of sound pressures measured at frequencies higher than 2 Hz inside two cavities coupled through a conventional loudspeaker. The basic method showed that the imaginary part of the sound pressure ratio is useful for the evaluation of the air-flow resistance. Criteria are discussed about the choice of a frequency range suitable to perform simplified calculations with respect to the basic method. These criteria depend on the sample thickness, its nonacoustic parameters, and the measurement apparatus as well. The proposed measurement method was tested successfully with various types of acoustic materials.

  15. VOLATILECALC: A silicate melt-H2O-CO2 solution model written in Visual Basic for excel

    USGS Publications Warehouse

    Newman, S.; Lowenstern, J. B.

    2002-01-01

    We present solution models for the rhyolite-H2O-CO2 and basalt-H2O-CO2 systems at magmatic temperatures and pressures below ~ 5000 bar. The models are coded as macros written in Visual Basic for Applications, for use within MicrosoftR Excel (Office'98 and 2000). The series of macros, entitled VOLATILECALC, can calculate the following: (1) Saturation pressures for silicate melt of known dissolved H2O and CO2 concentrations and the corresponding equilibrium vapor composition; (2) open- and closed-system degassing paths (melt and vapor composition) for depressurizing rhyolitic and basaltic melts; (3) isobaric solubility curves for rhyolitic and basaltic melts; (4) isoplethic solubility curves (constant vapor composition) for rhyolitic and basaltic melts; (5) polybaric solubility curves for the two end members and (6) end member fugacities of H2O and CO2 vapors at magmatic temperatures. The basalt-H2O-CO2 macros in VOLATILECALC are capable of calculating melt-vapor solubility over a range of silicate-melt compositions by using the relationships provided by Dixon (American Mineralogist 82 (1997) 368). The output agrees well with the published solution models and experimental data for silicate melt-vapor systems for pressures below 5000 bar. ?? 2002 Elsevier Science Ltd. All rights reserved.

  16. Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations

    DOE PAGES

    He, Chiyang; Zhu, Zaifang; Gu, Congying; ...

    2012-01-09

    Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet andmore » outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (~3100 psi). Here, we further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides.« less

  17. V OLATILEC ALC: a silicate melt-H 2O-CO 2 solution model written in Visual Basic for excel

    NASA Astrophysics Data System (ADS)

    Newman, Sally; Lowenstern, Jacob B.

    2002-06-01

    We present solution models for the rhyolite-H 2O-CO 2 and basalt-H 2O-CO 2 systems at magmatic temperatures and pressures below ˜5000 bar. The models are coded as macros written in Visual Basic for Applications, for use within Microsoft ® Excel (Office'98 and 2000). The series of macros, entitled V OLATILEC ALC, can calculate the following: (1) Saturation pressures for silicate melt of known dissolved H 2O and CO 2 concentrations and the corresponding equilibrium vapor composition; (2) open- and closed-system degassing paths (melt and vapor composition) for depressurizing rhyolitic and basaltic melts; (3) isobaric solubility curves for rhyolitic and basaltic melts; (4) isoplethic solubility curves (constant vapor composition) for rhyolitic and basaltic melts; (5) polybaric solubility curves for the two end members and (6) end member fugacities of H 2O and CO 2 vapors at magmatic temperatures. The basalt-H 2O-CO 2 macros in V OLATILEC ALC are capable of calculating melt-vapor solubility over a range of silicate-melt compositions by using the relationships provided by Dixon (American Mineralogist 82 (1997) 368). The output agrees well with the published solution models and experimental data for silicate melt-vapor systems for pressures below 5000 bar.

  18. Comparison of Quasi-Conservative Pressure-Based and Fully-Conservative Formulations for the Simulation of Transcritical Flows

    NASA Astrophysics Data System (ADS)

    Lacaze, Guilhem; Oefelein, Joseph

    2016-11-01

    High-pressure flows are known to be challenging to simulate due to thermodynamic non-linearities occurring in the vicinity of the pseudo-boiling line. This study investigates the origin of this issue by analyzing the behavior of thermodynamic processes at elevated pressure and low temperature. We show that under transcritical conditions, non-linearities significantly amplify numerical errors associated with construction of fluxes. These errors affect the local density and energy balances, which in turn creates pressure oscillations. For that reason, solvers based on a conservative system of equations that transport density and total energy are subject to unphysical pressure variations in gradient regions. These perturbations hinder numerical stability and degrade the accuracy of predictions. To circumvent this problem, the governing system can be reformulated to a pressure-based treatment of energy. We present comparisons between the pressure-based and fully conservative formulations using a progressive set of canonical cases, including a cryogenic turbulent mixing layer at rocket engine conditions. Department of Energy, Office of Science, Basic Energy Sciences Program.

  19. Spatial Variation of Pressure in the Lyophilization Product Chamber Part 2: Experimental Measurements and Implications for Scale-up and Batch Uniformity.

    PubMed

    Sane, Pooja; Varma, Nikhil; Ganguly, Arnab; Pikal, Michael; Alexeenko, Alina; Bogner, Robin H

    2017-02-01

    Product temperature during the primary drying step of freeze-drying is controlled by a set point chamber pressure and shelf temperature. However, recent computational modeling suggests a possible variation in local chamber pressure. The current work presents an experimental verification of the local chamber pressure gradients in a lab-scale freeze-dryer. Pressure differences between the center and the edges of a lab-scale freeze-dryer shelf were measured as a function of sublimation flux and clearance between the sublimation front and the shelf above. A modest 3-mTorr difference in pressure was observed as the sublimation flux was doubled from 0.5 to 1.0 kg·h -1 ·m -2 at a clearance of 2.6 cm. Further, at a constant sublimation flux of 1.0 kg·h -1 ·m -2 , an 8-fold increase in the pressure drop was observed across the shelf as the clearance was decreased from 4 to 1.6 cm. Scale-up of the pressure variation from lab- to a manufacturing-scale freeze-dryer predicted an increased uniformity in drying rates across the batch for two frequently used pharmaceutical excipients (mannitol and sucrose at 5% w/w). However, at an atypical condition of shelf temperature of +10°C and chamber pressure of 50 mTorr, the product temperature in the center vials was calculated to be a degree higher than the edge vial for a low resistance product, thus reversing the typical edge and center vial behavior. Thus, the effect of local pressure variation is more significant at the manufacturing-scale than at a lab-scale and accounting for the contribution of variations in the local chamber pressures can improve success in scale-up.

  20. Interrelationships between intranarial pressure and biosonar clicks in the bottlenose dolphin (Tursiops truncatus)

    NASA Astrophysics Data System (ADS)

    Elsberry, Wesley R.; Cranford, Ted W.; Ridgway, Sam H.; Carder, Donald A.; Vanbonn, William G.; Blackwood, Diane J.; Carr, Jennifer A.; Evans, William E.

    2002-05-01

    Three Atlantic bottlenose dolphins (Tursiops truncatus) were given a target recognition biosonar task. During their performance of the task, both acoustic data in the far field and pressure within the bony nasal passages were digitally recorded (Elsberry et al., 1999). Analysis of over 15000 biosonar clicks provided new insights into odontocete biosonar sound production and is consistent with acoustic and pressure data taken from white whales (Delphinapterus leucas) during biosonar (Ridgway and Carder, 1988). Our work provides the first evidence for a minimum intranarial pressure during biosonar click production for any odontocete (11.8+/-0.5 kPascals over basal pressure). All three subjects exhibited nearly the same minimum tranarial pressure difference during biosonar click production. Clicks produced at or near this minimum intranarial pressure exhibited a wide range of acoustic power values. The acoustic power of a biosonar click was not highly correlated with intranarial pressure (R2=0.116). The radiated acoustic energy in biosonar clicks ranged from 1 to 1370 microJoules. Estimates of mechanical work during pressurization events were produced using a piston/cylinder model and intranarial volume data from prepared specimens and computed tomography scans. Mechanical work during pressurization events ranged from 2.74 to 23.0 Joules, with an average of 10.3 Joules.

  1. Characterizing the impact of pressure on virus filtration processes and establishing design spaces to ensure effective parvovirus removal.

    PubMed

    Strauss, Daniel; Goldstein, Joshua; Hongo-Hirasaki, Tomoko; Yokoyama, Yoshiro; Hirotomi, Naokatsu; Miyabayashi, Tomoyuki; Vacante, Dominick

    2017-09-01

    Virus filtration provides robust removal of potential viral contaminants and is a critical step during the manufacture of biotherapeutic products. However, recent studies have shown that small virus removal can be impacted by low operating pressure and depressurization. To better understand the impact of these conditions and to define robust virus filtration design spaces, we conducted multivariate analyses to evaluate parvovirus removal over wide ranges of operating pressure, solution pH, and conductivity for three mAb products on Planova™ BioEX and 20N filters. Pressure ranges from 0.69 to 3.43 bar (10.0-49.7 psi) for Planova BioEX filters and from 0.50 to 1.10 bar (7.3 to 16.0 psi) for Planova 20N filters were identified as ranges over which effective removal of parvovirus is achieved for different products over wide ranges of pH and conductivity. Viral clearance at operating pressure below the robust pressure range suggests that effective parvovirus removal can be achieved at low pressure but that Minute virus of mice (MVM) logarithmic reduction value (LRV) results may be impacted by product and solution conditions. These results establish robust design spaces for Planova BioEX and 20N filters where high parvovirus clearance can be expected for most antibody products and provide further understanding of viral clearance mechanisms. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1294-1302, 2017. © 2017 American Institute of Chemical Engineers.

  2. Application and possible benefits of high hydrostatic pressure or high-pressure homogenization on beer processing: A review.

    PubMed

    Santos, Lígia Mr; Oliveira, Fabiano A; Ferreira, Elisa Hr; Rosenthal, Amauri

    2017-10-01

    Beer is the most consumed beverage in the world, especially in countries such as USA, China and Brazil.It is an alcoholic beverage made from malted cereals, and the barley malt is the main ingredient, added with water, hops and yeast. High-pressure processing is a non-traditional method to preserve food and beverages. This technology has become more interesting compared to heat pasteurization, due to the minimal changes it brings to the original nutritional and sensory characteristics of the product, and it comprises two processes: high hydrostatic pressure, which is the most industrially used process, and high-pressure homogenization. The use of high pressure almost does not affect the molecules that are responsible for the aroma and taste, pigments and vitamins compared to the conventional thermal processes. Thus, the products processed by high-pressure processing have similar characteristics compared to fresh products, including beer. The aim of this paper was to review what has been investigated about beer processing using this technology regarding the effects on physicochemical, microbiology and sensory characteristics and related issues. It is organized by processing steps, since high pressure can be applied to malting, mashing, boiling, filtration and pasteurization. Therefore, the beer processed with high-pressure processing may have an extended shelf-life because this process can inactivate beer spoilage microorganisms and result in a superior sensory quality related to freshness and preservation of flavors as it does to juices that are already commercialized. However, beyond this application, high-pressure processing can modify protein structures, such as enzymes that are present in the malt, like α- and β-amylases. This process can activate enzymes to promote, for example, saccharification, or instead inactivate at the end of mashing, depending on the pressure the product is submitted, besides being capable of isomerizing hops to raise beer bitterness. As a consequence, the process may reduce steam demand and residue generation. Therefore, the use of high-pressure processing can potentially replace or be combined with heat processes usually applied to beer, thus bringing benefits to the sensory quality of the product and to the environment.

  3. Effect of high hydrostatic pressure treatment on isoquercetin production from rutin by commercial α-L-rhamnosidase.

    PubMed

    Kim, Do-Yeon; Yeom, Soo-Jin; Park, Chang-Su; Kim, Yeong-Su

    2016-10-01

    To optimize conversion of rutin to isoquercetin by commercial α-L-rhamnosidase using high hydrostatic pressure (HHP). The de-rhamnosylation activity of α-L-rhamnosidase for isoquercetin production was maximal at pH 6.0 and 50 °C using HHP (150 MPa). The enzyme showed high specificity for rutin. The specific activity for rutin at HHP was 1.5-fold higher than that at atmospheric pressure. The enzyme completely hydrolysed 20 mM rutin in tartary buckwheat extract after 2 h at HHP, with a productivity of 10 mM h(-1). The productivity and conversion were 2.2- and 1.5-fold higher at HHP than at atmospheric pressure, respectively. This is the first report concerning the enzymatic hydrolysis of isoquercetin in tartary buckwheat at HHP.

  4. Origin of coronal mass ejection and magnetic cloud: Thermal or magnetic driven?

    NASA Technical Reports Server (NTRS)

    Zhang, Gong-Liang; Wang, Chi; He, Shuang-Hua

    1995-01-01

    A fundamental problem in Solar-Terrestrial Physics is the origin of the solar transient plasma output, which includes the coronal mass ejection and its interplanetary manifestation, e.g. the magnetic cloud. The traditional blast wave model resulted from solar thermal pressure impulse has faced with challenge during recent years. In the MHD numerical simulation study of CME, the authors find that the basic feature of the asymmetrical event on 18 August 1980 can be reproduced neither by a thermal pressure nor by a speed increment. Also, the thermal pressure model fails in simulating the interplanetary structure with low thermal pressure and strong magnetic field strength, representative of a typical magnetic cloud. Instead, the numerical simulation results are in favor of the magnetic field expansion as the likely mechanism for both the asymmetrical CME event and magnetic cloud.

  5. Fiber optic plantar pressure/shear sensor

    NASA Astrophysics Data System (ADS)

    Soetanto, William; Nguyen, Ngoc T.; Wang, Wei-Chih

    2011-04-01

    A full-scale foot pressure/shear sensor that has been developed to help diagnose the cause of ulcer formation in diabetic patients is presented. The design involves a tactile sensor array using intersecting optical fibers embedded in soft elastomer. The basic configuration incorporates a mesh that is comprised of two sets of parallel optical fiber plane; the planes are configured so the parallel rows of fiber of the top and bottom planes are perpendicular to each other. Threedimensional information is determined by measuring the loss of light from each of the waveguide to map the overall pressure distribution and the shifting of the layers relative to each other. In this paper we will present the latest development on the fiber optic plantar pressure/shear sensor which can measure normal force up from 19.09 kPa to 1000 kPa.

  6. Do Arthroscopic Fluid Pumps Display True Surgical Site Pressure During Hip Arthroscopy?

    PubMed

    Ross, Jeremy A; Marland, Jennifer D; Payne, Brayden; Whiting, Daniel R; West, Hugh S

    2018-01-01

    To report on the accuracy of 5 commercially available arthroscopic fluid pumps to measure fluid pressure at the surgical site during hip arthroscopy. Patients undergoing hip arthroscopy for femoroacetabular impingement were block randomized to the use of 1 of 5 arthroscopic fluid pumps. A spinal needle inserted into the operative field was used to measure surgical site pressure. Displayed pump pressures and surgical site pressures were recorded at 30-second intervals for the duration of the case. Mean differences between displayed pump pressures and surgical site pressures were obtained for each pump group. Of the 5 pumps studied, 3 (Crossflow, 24K, and Continuous Wave III) reflected the operative field fluid pressure within 11 mm Hg of the pressure readout. In contrast, 2 of the 5 pumps (Double Pump RF and FMS/DUO+) showed a difference of greater than 59 mm Hg between the operative field fluid pressure and the pressure readout. Joint-calibrated pumps more closely reflect true surgical site pressure than gravity-equivalent pumps. With a basic understanding of pump design, either type of pump can be used safely and efficiently. The risk of unfamiliarity with these differences is, on one end, the possibility of pump underperformance and, on the other, potentially dangerously high operating pressures. Level II, prospective block-randomized study. Copyright © 2017. Published by Elsevier Inc.

  7. Analysis of the high-temperature particulate collection problem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Razgaitis, R.

    1977-10-01

    Particulate agglomeration and separation at high temperatures and pressures are examined, with particular emphasis on the unique features of the direct-cycle application of fluidized-bed combustion. The basic long-range mechanisms of aerosol separation are examined, and the effects of high temperature and high pressure on usable collection techniques are assessed. Primary emphasis is placed on those avenues that are not currently attracting widespread research. The high-temperature, particulate-collection problem is surveyed, together with the peculiar requirements associated with operation of turbines with particulate-bearing gas streams. 238 references.

  8. [Functional state of various physiological systems of the human body during respiration of neon-oxygen mixture at depth up to 400 meters].

    PubMed

    Poleshuk, I P; Genin, A M; Unku, R D; Mikhnenko, A E; Sementsov, V N; Suvorov, A V

    1991-01-01

    Hyperbaric neon-oxygen mixture has been studied for the effect of its high density under pressure of 41 ata on basic physiological functions of human organism. Typical changes of the cardiorespiratory system and tissue respiration parameters are revealed. Changes in physical working capacity are shown. Exposure to gaseous medium of high pressure and density is accompanied by the development of some compensatory-adaptive reactions. The possibility to perform mid-hard physical work is attained with overstrain of respiration and circulation function.

  9. CF6 jet engine performance improvement: High pressure turbine roundness

    NASA Technical Reports Server (NTRS)

    Howard, W. D.; Fasching, W. A.

    1982-01-01

    An improved high pressure turbine stator reducing fuel consumption in current CF6-50 turbofan engines was developed. The feasibility of the roundness and clearance response improvements was demonstrated. Application of these improvements will result in a cruise SFC reduction of 0.22 percent for new engines. For high time engines, the improved roundness and response characteristics results in an 0.5 percent reduction in cruise SFC. A basic life capability of the improved HP turbine stator in over 800 simulated flight cycles without any sign of significant distress is shown.

  10. Experimental and computational flow-field results for an all-body hypersonic aircraft

    NASA Technical Reports Server (NTRS)

    Cleary, Joseph W.

    1989-01-01

    A comprehensive test program is defined which is being implemented in the NASA/Ames 3.5 foot Hypersonic Wind Tunnel for obtaining data on a generic all-body hypersonic vehicle for computational fluid dynamics (CFD) code validation. Computational methods (approximate inviscid methods and an upwind parabolized Navier-Stokes code) currently being applied to the all-body model are outlined. Experimental and computational results on surface pressure distributions and Pitot-pressure surveys for the basic sharp-nose model (without control surfaces) at a free-stream Mach number of 7 are presented.

  11. High temperature NASP engine seals: A technology review

    NASA Technical Reports Server (NTRS)

    Steinetz, Bruce M.; Dellacorte, Christopher; Tong, Mike

    1991-01-01

    Progress in developing advanced high temperature engine seal concepts and related sealing technologies for advanced hypersonic engines are reviewed. Design attributes and issues requiring further development for both the ceramic wafer seal and the braided ceramic rope seal are examined. Leakage data are presented for these seals for engine simulated pressure and temperature conditions and compared to a target leakage limit. Basic elements of leakage flow models to predict leakage rates for each of these seals over the wide range of pressure and temperature conditions anticipated in the engine are also presented.

  12. Switching skeletons: hydrostatic support in molting crabs

    NASA Technical Reports Server (NTRS)

    Taylor, Jennifer R A.; Kier, William M.; Walker, I. D. (Principal Investigator)

    2003-01-01

    Skeletal support systems are essential for support, movement, muscular antagonism, and locomotion. Crustaceans shed their rigid exoskeleton at each molt yet are still capable of forceful movement. We hypothesize that the soft water-inflated body of newly molted crabs may rely on a hydrostatic skeleton, similar to that of worms and polyps. We measured internal hydrostatic pressure and the force exerted during claw adduction and observed a strong correlation between force and hydrostatic pressure, consistent with hydrostatic skeletal support. This alternation between the two basic skeletal types may be widespread among arthropods.

  13. Hydrogen separation process

    DOEpatents

    Mundschau, Michael [Longmont, CO; Xie, Xiaobing [Foster City, CA; Evenson, IV, Carl; Grimmer, Paul [Longmont, CO; Wright, Harold [Longmont, CO

    2011-05-24

    A method for separating a hydrogen-rich product stream from a feed stream comprising hydrogen and at least one carbon-containing gas, comprising feeding the feed stream, at an inlet pressure greater than atmospheric pressure and a temperature greater than 200.degree. C., to a hydrogen separation membrane system comprising a membrane that is selectively permeable to hydrogen, and producing a hydrogen-rich permeate product stream on the permeate side of the membrane and a carbon dioxide-rich product raffinate stream on the raffinate side of the membrane. A method for separating a hydrogen-rich product stream from a feed stream comprising hydrogen and at least one carbon-containing gas, comprising feeding the feed stream, at an inlet pressure greater than atmospheric pressure and a temperature greater than 200.degree. C., to an integrated water gas shift/hydrogen separation membrane system wherein the hydrogen separation membrane system comprises a membrane that is selectively permeable to hydrogen, and producing a hydrogen-rich permeate product stream on the permeate side of the membrane and a carbon dioxide-rich product raffinate stream on the raffinate side of the membrane. A method for pretreating a membrane, comprising: heating the membrane to a desired operating temperature and desired feed pressure in a flow of inert gas for a sufficient time to cause the membrane to mechanically deform; decreasing the feed pressure to approximately ambient pressure; and optionally, flowing an oxidizing agent across the membrane before, during, or after deformation of the membrane. A method of supporting a hydrogen separation membrane system comprising selecting a hydrogen separation membrane system comprising one or more catalyst outer layers deposited on a hydrogen transport membrane layer and sealing the hydrogen separation membrane system to a porous support.

  14. Competency Testing: Assessment or Politics? Draft.

    ERIC Educational Resources Information Center

    Carter, David G., Sr.

    Competency testing legislation is the result of citizen pressure and lacks the benefit of careful deliberation by professionals. Hastily passed legislation has forced state departments of education and school districts to accept their duty to implement competency testing programs without the appropriate resources. Many of the basic problems of…

  15. DEMONSTRATION BULLETIN: BESCORP SOIL WASHING SYSTEM ALASKAN BATTERY ENTERPRISES SITE - BRICE ENVIRONMENTAL SERVICES CORPORATION

    EPA Science Inventory

    The BESCORP Soil Washing System is an aqueous volume reduction system that utilizes trommel agitation, high-pressure washing, sizing, and density separation to remove lead, lead compounds, and battery casing chips from soil contaminated by broken lead batteries. The basic concept...

  16. Preliminary investigation of the relationship between capillary pore pressure and early shrinkage cracking of concrete.

    DOT National Transportation Integrated Search

    1997-01-01

    The purpose of this study was to design experimental laboratory equipment and perform experiments to investigate the basic physical processes that occur in concrete for periods of several hours to several days after mixing. The study was conducted in...

  17. 21 CFR 177.1620 - Polyethylene, oxidized.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: POLYMERS Substances for Use as Basic...,200, as determined by high temperature vapor pressure osmometry, contains a maximum of 5 percent by weight of total oxygen, and has an acid value of 9 to 19. (b) The finished food-contact article, when...

  18. 21 CFR 177.1620 - Polyethylene, oxidized.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: POLYMERS Substances for Use as Basic...,200, as determined by high temperature vapor pressure osmometry, contains a maximum of 5 percent by weight of total oxygen, and has an acid value of 9 to 19. (b) The finished food-contact article, when...

  19. 21 CFR 177.1620 - Polyethylene, oxidized.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: POLYMERS Substances for Use as Basic...,200, as determined by high temperature vapor pressure osmometry, contains a maximum of 5 percent by weight of total oxygen, and has an acid value of 9 to 19. (b) The finished food-contact article, when...

  20. 21 CFR 177.1620 - Polyethylene, oxidized.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: POLYMERS Substances for Use as Basic...,200, as determined by high temperature vapor pressure osmometry, contains a maximum of 5 percent by weight of total oxygen, and has an acid value of 9 to 19. (b) The finished food-contact article, when...

  1. Basic Microvascular Anastomosis Simulation Hub Microsurgery Course: An Innovative Competency-Based Approach to Microsurgical Training for Early Year's Plastic Surgery Trainees.

    PubMed

    Ali, Stephen

    2018-04-01

    Early year's plastic surgery trainees are faced with a large choice of microsurgery courses to select from. In the context of dwindling study budgets and busy on-call rotas, the pressure to select a high yield course that delivers value for money is of paramount importance.The Basic Microvascular Anastomosis Simulation Hub Microsurgery Course is a GBP £600 (US $790) 5-day 40-hour course based at Barts and The London School of Medicine and Dentistry increasing in popularity among junior trainees to fit this brief.

  2. EVA Glove Research Team

    NASA Technical Reports Server (NTRS)

    Strauss, Alvin M.; Peterson, Steven W.; Main, John A.; Dickenson, Rueben D.; Shields, Bobby L.; Lorenz, Christine H.

    1992-01-01

    The goal of the basic research portion of the extravehicular activity (EVA) glove research program is to gain a greater understanding of the kinematics of the hand, the characteristics of the pressurized EVA glove, and the interaction of the two. Examination of the literature showed that there existed no acceptable, non-invasive method of obtaining accurate biomechanical data on the hand. For this reason a project was initiated to develop magnetic resonance imaging as a tool for biomechanical data acquisition and visualization. Literature reviews also revealed a lack of practical modeling methods for fabric structures, so a basic science research program was also initiated in this area.

  3. How communication changes when we cannot mime the world: Experimental evidence for the effect of iconicity on combinatoriality.

    PubMed

    Roberts, Gareth; Lewandowski, Jirka; Galantucci, Bruno

    2015-08-01

    Communication systems are exposed to two different pressures: a pressure for transmission efficiency, such that messages are simple to produce and perceive, and a pressure for referential efficiency, such that messages are easy to understand with their intended meaning. A solution to the first pressure is combinatoriality--the recombination of a few basic meaningless forms to express an infinite number of meanings. A solution to the second is iconicity--the use of forms that resemble what they refer to. These two solutions appear to be incompatible with each other, as iconic forms are ill-suited for use as meaningless combinatorial units. Furthermore, in the early stages of a communication system, when basic referential forms are in the process of being established, the pressure for referential efficiency is likely to be particularly strong, which may lead it to trump the pressure for transmission efficiency. This means that, where iconicity is available as a strategy, it is likely to impede the emergence of combinatoriality. Although this hypothesis seems consistent with some observations of natural language, it was unclear until recently how it could be soundly tested. This has changed thanks to the development of a line of research, known as Experimental Semiotics, in which participants construct novel communication systems in the laboratory using an unfamiliar medium. We conducted an Experimental Semiotic study in which we manipulated the opportunity for iconicity by varying the kind of referents to be communicated, while keeping the communication medium constant. We then measured the combinatoriality and transmission efficiency of the communication systems. We found that, where iconicity was available, it provided scaffolding for the construction of communication systems and was overwhelmingly adopted. Where it was not available, however, the resulting communication systems were more combinatorial and their forms more efficient to produce. This study enriches our understanding of the fundamental design principles of human communication and contributes tools to enrich it further. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Design and construction of functional AAV vectors.

    PubMed

    Gray, John T; Zolotukhin, Serge

    2011-01-01

    Using the basic principles of molecular biology and laboratory techniques presented in this chapter, researchers should be able to create a wide variety of AAV vectors for both clinical and basic research applications. Basic vector design concepts are covered for both protein coding gene expression and small non-coding RNA gene expression cassettes. AAV plasmid vector backbones (available via AddGene) are described, along with critical sequence details for a variety of modular expression components that can be inserted as needed for specific applications. Protocols are provided for assembling the various DNA components into AAV vector plasmids in Escherichia coli, as well as for transferring these vector sequences into baculovirus genomes for large-scale production of AAV in the insect cell production system.

  5. Characterization of the basic charge variants of a human IgG1

    PubMed Central

    Lu, Franklin; Derfus, Gayle; Kluck, Brian; Nogal, Bartek; Emery, Craig; Summers, Christie; Zheng, Kai; Bayer, Robert; Amanullah, Ashraf

    2011-01-01

    We report a case study of an IgG1 with a unique basic charge variant profile caused by C-terminal proline amidation on either one or two heavy chains. The proline amidation was sensitive to copper ion concentration in the production media during cell culture: the higher the Cu2+ ion concentration, the higher the level of proline amidation detected. This conclusion was supported by the analysis of samples that revealed direct correlation between the proline amidation level observed from peptide maps and the level of basic peaks measured by imaged capillary isoelectric focusing and a pH gradient ion-exchange chromatography method. The importance of these observations to therapeutic antibody production is discussed. PMID:22123059

  6. Characterization of the basic charge variants of a human IgG1: effect of copper concentration in cell culture media.

    PubMed

    Kaschak, Timothy; Boyd, Daniel; Lu, Franklin; Derfus, Gayle; Kluck, Brian; Nogal, Bartek; Emery, Craig; Summers, Christie; Zheng, Kai; Bayer, Robert; Amanullah, Ashraf; Yan, Boxu

    2011-01-01

    We report a case study of an IgG1 with a unique basic charge variant profile caused by C-terminal proline amidation on either one or two heavy chains. The proline amidation was sensitive to copper ion concentration in the production media during cell culture: the higher the Cu ( 2+) ion concentration, the higher the level of proline amidation detected. This conclusion was supported by the analysis of samples that revealed direct correlation between the proline amidation level observed from peptide maps and the level of basic peaks measured by imaged capillary isoelectric focusing and a pH gradient ion-exchange chromatography method. The importance of these observations to therapeutic antibody production is discussed.

  7. A Brief Study on Toxic Combustion Products of the Polymers Used in High-Pressure Oxygen Systems

    NASA Technical Reports Server (NTRS)

    Hshieh, Fu-Yu; Beeson, Harold D.

    2005-01-01

    One likely cause of polymer ignition in a high-pressure oxygen system is the adiabatic-compression heating of polymers caused by pneumatic impact. Oxidative pyrolysis or combustion of polymers in a high-pressure oxygen system could generate toxic gases. This paper investigates the feasibility of using the NASA pneumatic-impact system to conduct adiabatic-compression combustion tests and determines the toxic combustion products produced from the burning of five selected polymers. Five polymers commonly used in high-pressure oxygen systems, Zytel(Registered TradeMark) 42 (Nylon 6/6), Buna N (nitrile rubber), Witon(Registered TradeMark) A (copolymer of vinylidene fluoride and hexafluoropropylene), Neoflon(Registered TradeMark) (polychlorotrifluoroethylene), and Teflon(Registered TradeMark) (polytetrafluoroethylene), were tested in the NASA pneumatic-impact test system at 17.2-MPa oxygen pressure. The polymers were ignited and burned; combustion products were collected in a stainless-steel sample bottle and analyzed using various methods. The results show that the NASA pneumatic-impact system is an appropriate test system to conduct adiabatic-compression combustion tests and to collect combustion products for further chemical analysis. The composition of the combustion product gas generated from burning the five selected polymers are presented and discussed.

  8. In situ gasification process for producing product gas enriched in carbon monoxide and hydrogen

    DOEpatents

    Capp, John P.; Bissett, Larry A.

    1978-01-01

    The present invention is directed to an in situ coal gasification process wherein the combustion zone within the underground coal bed is fed with air at increasing pressure to increase pressure and temperature in the combustion zone for forcing product gases and water naturally present in the coal bed into the coal bed surrounding the combustion zone. No outflow of combustion products occurs during the build-up of pressure and temperature in the combustion zone. After the coal bed reaches a temperature of about 2000.degree. F and a pressure in the range of about 100-200 psi above pore pressure the airflow is terminated and the outflow of the combustion products from the combustion zone is initiated. The CO.sub.2 containing gaseous products and the water bleed back into the combustion zone to react endothermically with the hot carbon of the combustion zone to produce a burnable gas with a relatively high hydrogen and carbon monoxide content. About 11 to 29 percent of the gas recovered from the combustion zone is carbon monoxide which is considerably better than the 4 to 10 percent carbon monoxide obtained by employing previously known coal gasification techniques.

  9. The Product and Quotient Rules Revisited

    ERIC Educational Resources Information Center

    Eggleton, Roger; Kustov, Vladimir

    2011-01-01

    Mathematical elegance is illustrated by strikingly parallel versions of the product and quotient rules of basic calculus, with some applications. Corresponding rules for second derivatives are given: the product rule is familiar, but the quotient rule is less so.

  10. Freeze-drying process design by manometric temperature measurement: design of a smart freeze-dryer.

    PubMed

    Tang, Xiaolin Charlie; Nail, Steven L; Pikal, Michael J

    2005-04-01

    To develop a procedure based on manometric temperature measurement (MTM) and an expert system for good practices in freeze drying that will allow development of an optimized freeze-drying process during a single laboratory freeze-drying experiment. Freeze drying was performed with a FTS Dura-Stop/Dura-Top freeze dryer with the manometric temperature measurement software installed. Five percent solutions of glycine, sucrose, or mannitol with 2 ml to 4 ml fill in 5 ml vials were used, with all vials loaded on one shelf. Details of freezing, optimization of chamber pressure, target product temperature, and some aspects of secondary drying are determined by the expert system algorithms. MTM measurements were used to select the optimum shelf temperature, to determine drying end points, and to evaluate residual moisture content in real-time. MTM measurements were made at 1 hour or half-hour intervals during primary drying and secondary drying, with a data collection frequency of 4 points per second. The improved MTM equations were fit to pressure-time data generated by the MTM procedure using Microcal Origin software to obtain product temperature and dry layer resistance. Using heat and mass transfer theory, the MTM results were used to evaluate mass and heat transfer rates and to estimate the shelf temperature required to maintain the target product temperature. MTM product dry layer resistance is accurate until about two-thirds of total primary drying time is over, and the MTM product temperature is normally accurate almost to the end of primary drying provided that effective thermal shielding is used in the freeze-drying process. The primary drying times can be accurately estimated from mass transfer rates calculated very early in the run, and we find the target product temperature can be achieved and maintained with only a few adjustments of shelf temperature. The freeze-dryer overload conditions can be estimated by calculation of heat/mass flow at the target product temperature. It was found that the MTM results serve as an excellent indicator of the end point of primary drying. Further, we find that the rate of water desorption during secondary drying may be accurately measured by a variation of the basic MTM procedure. Thus, both the end point of secondary drying and real-time residual moisture may be obtained during secondary drying. Manometric temperature measurement and the expert system for good practices in freeze drying does allow development of an optimized freeze-drying process during a single laboratory freeze-drying experiment.

  11. 40 CFR 61.341 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to industrial organic chemicals, organic pesticide products, pharmaceutical preparations, paint and allied products, fertilizers, and agricultural chemicals. Examples of chemical manufacturing plants...). Maximum organic vapor pressure means the equilibrium partial pressure exerted by the waste at the...

  12. Production Scheduling for Rehabilitation Workshops.

    ERIC Educational Resources Information Center

    Hietala, David A.

    This publication examines production scheduling procedures for sheltered workshops. The manual includes three major sections: (1) the importance and benefits of production scheduling; (2) how-to information on performing basic scheduling in the workshop; and (3) answers to the question, What makes production scheduling work? The scheduling…

  13. An analytical model for pressure of volume fractured tight oil reservoir with horizontal well

    NASA Astrophysics Data System (ADS)

    Feng, Qihong; Dou, Kaiwen; Zhang, Xianmin; Xing, Xiangdong; Xia, Tian

    2017-05-01

    The property of tight oil reservoir is worse than common reservoir that we usually seen before, the porosity and permeability is low, the diffusion is very complex. Therefore, the ordinary depletion method is useless here. The volume fracture breaks through the conventional EOR mechanism, which set the target by amplifying the contact area of fracture and reservoir so as to improving the production of every single well. In order to forecast the production effectively, we use the traditional dual-porosity model, build an analytical model for production of volume fractured tight oil reservoir with horizontal well, and get the analytical solution in Laplace domain. Then we construct the log-log plot of dimensionless pressure and time by stiffest conversion. After that, we discuss the influential factors of pressure. Several factors like cross flow, skin factors and threshold pressure gradient was analyzed in the article. This model provides a useful method for tight oil production forecast and it has certain guiding significance for the production capacity prediction and dynamic analysis.

  14. Gas Requirements in Pressurized Transfer of Liquid Hydrogen

    NASA Technical Reports Server (NTRS)

    Gluck, D. F.; Kline, J. F.

    1961-01-01

    Of late, liquid hydrogen has become a very popular fuel for space missions. It is being used in such programs as Centaur and Saturn. Furthermore, hydrogen is the ideal working fluid for nuclear powered space vehicles currently under development. In these applications, liquid hydrogen fuel is generally transferred to the combustion chamber by a combination of pumping and pressurization. The pump forces the liquid propellant from the fuel tank to the combustion chamber; gaseous pressurant holds tank pressure sufficiently high to prevent cavitation at the pump inlet and to maintain the structural rigidity of the tank. The pressurizing system, composed of pressurant, tankage, and associated hardware can be a large portion of the total vehicle weight. Pressurant weight can be reduced by introducing the pressurizing gas at temperatures substantially greater than those of liquid hydrogen. Heat and mass transfer processes thereby induced complicate gas requirements during discharge. These requirements must be known to insure proper design of the pressurizing system. The aim of this paper is to develop from basic mass and energy transfer processes a general method to predict helium and hydrogen gas usage for the pressurized transfer of liquid hydrogen. This required an analytical and experimental investigation, the results of which are described in this paper.

  15. Non-Linear Effects in Knowledge Production

    NASA Astrophysics Data System (ADS)

    Purica, Ionut

    2007-04-01

    The generation of technological knowledge is paramount to our present development; the production of technological knowledge is governed by the same Cobb Douglas type model, with the means of research and the intelligence level replacing capital, respectively labor. We are exploring the basic behavior of present days' economies that are producing technological knowledge, along with the `usual' industrial production and determine a basic behavior that turns out to be a `Henon attractor'. Measures are introduced for the gain of technological knowledge and for the information of technological sequences that are based respectively on the underlying multi-valued modal logic of the technological research and on nonlinear thermodynamic considerations.

  16. Report on ISS O2 Production, Gas Supply and Partial Pressure Management

    NASA Technical Reports Server (NTRS)

    Schaezler, Ryan N.; Cook, Anthony J.

    2015-01-01

    Oxygen is used on International Space Station (ISS) for metabolic support and denitrogenation procedures prior to Extra-Vehicular Activities. Nitrogen is used to maintain total pressure and account for losses associated with leakage and operational losses. Oxygen and nitrogen have been supplied by various visiting vehicles such as the Progress and Shuttle in addition to the on-orbit oxygen production capability. Starting in 2014, new high pressure oxygen/nitrogen tanks are available to launch on commercial cargo vehicles and will replace the high pressure gas source that Shuttle used to provide. To maintain a habitable atmosphere the oxygen and nitrogen partial pressures are controlled between upper and lower bounds. The full range of the allowable partial pressures along with the increased ISS cabin volume are utilized as a buffer allowing days to pass between oxygen production or direct addition of oxygen and nitrogen to the atmosphere from reserves. This paper summarizes the amount of gas supplied and produced from all of the sources and describes past experience of managing partial pressures along with the range of management options available to the ISS.

  17. Clinical Issues-November 2017.

    PubMed

    Johnstone, Esther M

    2017-11-01

    Heating, ventilation, and air-conditioning (HVAC) systems in the OR Key words: airborne contaminants, HVAC system, air pressure, air quality, temperature and humidity. Air changes and positive pressure Key words: air changes, positive pressure airflow, unidirectional airflow, outdoor air, recirculated air. Product selection Key word: product evaluation, product selection, selection committee. Entry into practice Key words: associate degree in nursing, bachelor of science in nursing, entry-level position, advanced education, BSN-prepared RNs. Mentoring in perioperative nursing Key words: mentor, novice, practice improvement, nursing workforce. Copyright © 2017 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  18. National Waterways Study: Findings and Conclusions (from Contractor Study Effort).

    DTIC Science & Technology

    1982-05-01

    basic process by which decisions are made by the Congress on the allocation of investments in the navigation system and the levels of funding for...waterways structures anticipates no significant change in the basic navigation technology in the foreseeable future* However, better management of the...other products discussed in this section. " As a result, water transportation handles only about one quarter of all basic and intermediate industrial

  19. 21 CFR 320.25 - Guidelines for the conduct of an in vivo bioavailability study.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... physician determines that there is a potential benefit to the patient. (b) Basic design. The basic design of... to or to meet any comparative labeling claims made in relation to the drug product that is the...

  20. 21 CFR 320.25 - Guidelines for the conduct of an in vivo bioavailability study.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... physician determines that there is a potential benefit to the patient. (b) Basic design. The basic design of... to or to meet any comparative labeling claims made in relation to the drug product that is the...

  1. 21 CFR 320.25 - Guidelines for the conduct of an in vivo bioavailability study.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... physician determines that there is a potential benefit to the patient. (b) Basic design. The basic design of... to or to meet any comparative labeling claims made in relation to the drug product that is the...

  2. 21 CFR 320.25 - Guidelines for the conduct of an in vivo bioavailability study.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... physician determines that there is a potential benefit to the patient. (b) Basic design. The basic design of... to or to meet any comparative labeling claims made in relation to the drug product that is the...

  3. Learning Resources Evaluations Manual.

    ERIC Educational Resources Information Center

    Nunes, Evelyn H., Ed.

    This manual contains evaluations of 196 instructional products listed in Virginia's Adult Basic Education Curricula Resource Catalog. It is intended as a convenient reference manual for making informed decisions concerning materials for adult learners in adult basic education, English-as-a-Second-Language instruction, and general educational…

  4. 10 CFR 605.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... definitions are provided for purposes of this part— Basic and applied research means basic and applied research and that part of development not related to the development of specific systems or products. The... ENERGY (CONTINUED) ASSISTANCE REGULATIONS THE OFFICE OF ENERGY RESEARCH FINANCIAL ASSISTANCE PROGRAM...

  5. Understanding and Observing Subglacial Friction Using Seismology

    NASA Astrophysics Data System (ADS)

    Tsai, V. C.

    2017-12-01

    Glaciology began with a focus on understanding basic mechanical processes and producing physical models that could explain the principal observations. Recently, however, more attention has been paid to the wealth of recent observations, with many modeling efforts relying on data assimilation and empirical scalings, rather than being based on first-principles physics. Notably, ice sheet models commonly assume that subglacial friction is characterized by a "slipperiness" coefficient that is determined by inverting surface velocity observations. Predictions are usually then made by assuming these slipperiness coefficients are spatially and temporally fixed. However, this is only valid if slipperiness is an unchanging material property of the bed and, despite decades of work on subglacial friction, it has remained unclear how to best account for such subglacial physics in ice sheet models. Here, we describe how basic seismological concepts and observations can be used to improve our understanding and determination of subglacial friction. First, we discuss how standard models of granular friction can and should be used in basal friction laws for marine ice sheets, where very low effective pressures exist. We show that under realistic West Antarctic Ice Sheet conditions, standard Coulomb friction should apply in a relatively narrow zone near the grounding line and that this should transition abruptly as one moves inland to a different, perhaps Weertman-style, dependence of subglacial stress on velocity. We show that this subglacial friction law predicts significantly different ice sheet behavior even as compared with other friction laws that include effective pressure. Secondly, we explain how seismological observations of water flow noise and basal icequakes constrain subglacial physics in important ways. Seismically observed water flow noise can provide constraints on water pressures and channel sizes and geometry, leading to important data on subglacial friction. Basal icequake mechanisms also provide unique constraints on subglacial stress state as well as variations in water pressures. Together, the use of standard seismological concepts and new observations thus promises to provide new constraints on subglacial mechanics and focus attention back on the basic physical processes involved.

  6. [Effects of the renal blood flow at different levels by transcutaneous electrical acupoint stimulation combined general anesthesia induced controlled hypotension].

    PubMed

    Fang, Jian-Qiao; Zhang, Le-Le; Shao, Xiao-Mei

    2012-11-01

    To observe the intervention of transcutaneous electrical acupoint stimulation (TEAS) on the renal blood flow at different levels of mean arterial pressure (MAP) in controlled hypotension. Forty-two male beagle dogs were randomly divided into seven groups, i. e., the general anesthesia group, the 50% controlled group, the 40% controlled group, the 30% controlled group, the 50% experimental group, the 40% experimental group, and the 30% experimental group, 6 in each group. Beagles in the general anesthesia group were not treated with controlled hypotension, and the target MAP was achieved in those of the rest groups and maintained for 60 min. In the experimental groups, TEAS was applied to bilateral Hegu (LI4), Zusanli (ST36), Sanyinjiao (SP6), and Quchi (LI11) at 2/100 Hz with the stimulation strength of (4 +/- 1) mA starting from the stability of their physiological conditions to 60 min of maintaining the target MAP level. The changes of the renal blood flow were monitored at different time points using laser Doppler. From starting pressure control to the target MAP level, the renal blood flow was significantly lower in the 30% controlled group than in the general anesthesia group and the basic level of the same group (P < 0.05), while there was no obvious change in the 30% experimental group. In maintaining the blood pressure, the renal blood flow was significantly lower in the 50% controlled group, the 40% controlled group, the 30% controlled group, and the 30% experimental group than in the general anesthesia group (P < 0.05), while there was no obvious change in the 50% experimental group or the 40% experimental group. By the end of blood pressure recovery, the renal blood flow restored to the basic level in the 50% controlled group, the 50% experimental group, and the 40% experimental group (P > 0.05), while it was not restored to the basic level in the 40% controlled group, the 30% controlled group, and the 30% experimental group (P < 0.05). TEAS combined general anesthesia in controlled hypotension could effectively improve the renal blood flow, thus protecting the kidney.

  7. Light Sources and Lighting Circuits

    NASA Astrophysics Data System (ADS)

    Honda, Hisashi; Suwa, Takumi; Yasuda, Takeo; Ohtani, Yoshihiko; Maehara, Akiyoshi; Okada, Atsunori; Komatsu, Naoki; Mannami, Tomoaki

    According to the Machinery Statistics of the Ministry of Economy, Trade and Industry, the production of incandescent lamps in Japan in 2007 was 990 million units (90.0% of the previous year's total), in which the production of incandescent lamps for general lighting was 110 million units (90.0% of the previous year's total) and of tungsten-halogen lamps was 44 million units (96.6% of the previous year's total). The production of fluorescent lamps was 927 million units (93.9% of the previous year's total), in which general fluorescent lamps, excluding those for LCD back lighting, was 320 million units (87.2% of the previous year's total). Also, the production of HID lamps was 10 million units (101.5% of the previous year's total). On the other hand, when the numbers of sales are compared with the sales of the previous year, incandescent lamps for general use was 99.8%, tungsten-halogen lamps was 96.9%, fluorescent lamps was 95.9%, and HID lamps was 98.9%. Self-ballasted fluorescent lamps alone showed an increase in sales as strong as 29 million units, or 121.7% of the previous year's sales. It is considered that the switchover of incandescent lamps to HID lamps was promoted for energy conservation and carbon dioxide reduction with the problem of global warming in the background. In regard to exhibitions, Lighting Fair 2007 was held in Tokyo in March, and LIGHTFAIR INTERNATIONAL 2007 was held in New York in May. Regarding academic conferences, LS:11 (the 11th International Symposium on the Science & Technology of Light Sources) was held in Shanghai in May, and the First International Conference on White LEDs and Solid State Lighting was held in Tokyo in November. Both conferences suggested that there are strong needs and concerns now about energy conservation, saving natural resources, and restrictions of hazardous materials. In regard to incandescent lamps, the development of products aiming at higher efficacy, electric power savings, and longer life was advanced by means of using filler gas with a higher atomic weight. Regarding fluorescent lamps, studies and developments for longer operating life and improvement in the lumen maintenance factor for the straight-type and circular-type fluorescent lamps were actively pursued. Regarding self-ballasted fluorescent lamps, the main stream of development was aimed at reducing lamp size and increasing energy conservation, and the development of new products that took advantage of these features proceeded. In regard to LED light sources, basic research and product development, including new application development, were vigorously implemented. In basic research, studies were reported, not only on efficacy improvements through optimization of the LED chips, phosphor layers, and packaging technology, but also on photometry, colorimetry, and visual psychology. In the field of application, applications were studied for general lighting sources and also for a wide range of fields, such as automotive headlights and visible light communication. Also, many academic conferences and exhibitions were held domestically and overseas, and the high level of interest suggests high expectations for this next-generation light source. Regarding HID lamps, there was much activity in research and development and in the commercialization of the ceramic metal halide lamp product, and products were commercialized with features such as higher efficiency (130 lm/W) and higher color rendering properties (R9 ≥ 90). In the high-pressure sodium lamps, there were many study reports concerning plant growth and insect pest control using its low insect-attracting characteristics. With high-pressure mercury lamps, there were many reports on reducing lamp size and increasing intensity for use as a light source for projectors.

  8. Pressurized metallurgy for high performance special steels and alloys

    NASA Astrophysics Data System (ADS)

    Jiang, Z. H.; Zhu, H. C.; Li, H. B.; Li, Y.; Liu, F. B.

    2016-07-01

    The pressure is one of the basic parameters which greatly influences the metallurgical reaction process and solidification of steels and alloys. In this paper the history and present situation of research and application of pressurized metallurgy, especially pressurized metallurgy for special steels and alloys have been briefly reviewed. In the following part the physical chemistry of pressurized metallurgy is summarized. It is shown that pressurizing may change the conditions of chemical reaction in thermodynamics and kinetics due to the pressure effect on gas volume, solubility of gas and volatile element in metal melt, activity or activity coefficient of components, and change the physical and chemical properties of metal melt, heat transfer coefficient between mould and ingot, thus greatly influencing phase transformation during the solidification process and the solidification structure, such as increasing the solidification nucleation rate, reducing the critical nucleation radius, accelerating the solidification speed and significant macro/micro-structure refinement, and eliminating shrinkage, porosity and segregation and other casting defects. In the third part the research works of pressured metallurgy performed by the Northeastern University including establishment of pressurized induction melting (PIM) and pressurized electroslag remelting (PESR) equipments and development of high nitrogen steels under pressure are described in detail. Finally, it is considered in the paper that application of pressurized metallurgy in manufacture of high performance special steels and alloys is a relatively new research area, and its application prospects will be very broad and bright.

  9. Modelling of Seismic and Resistivity Responses during the Injection of CO2 in Sandstone Reservoir

    NASA Astrophysics Data System (ADS)

    Omar, Muhamad Nizarul Idhafi Bin; Almanna Lubis, Luluan; Nur Arif Zanuri, Muhammad; Ghosh, Deva P.; Irawan, Sonny; Regassa Jufar, Shiferaw

    2016-07-01

    Enhanced oil recovery plays vital role in production phase in a producing oil field. Initially, in many cases hydrocarbon will naturally flow to the well as respect to the reservoir pressure. But over time, hydrocarbon flow to the well will decrease as the pressure decrease and require recovery method so called enhanced oil recovery (EOR) to recover the hydrocarbon flow. Generally, EOR works by injecting substances, such as carbon dioxide (CO2) to form a pressure difference to establish a constant productive flow of hydrocarbon to production well. Monitoring CO2 performance is crucial in ensuring the right trajectory and pressure differences are established to make sure the technique works in recovering hydrocarbon flow. In this paper, we work on computer simulation method in monitoring CO2 performance by seismic and resistivity model, enabling geoscientists and reservoir engineers to monitor production behaviour as respect to CO2 injection.

  10. International urodynamic basic spinal cord injury data set.

    PubMed

    Biering-Sørensen, F; Craggs, M; Kennelly, M; Schick, E; Wyndaele, J-J

    2008-07-01

    To create the International Urodynamic Basic Spinal Cord Injury (SCI) Data Set within the framework of the International SCI Data Sets. International working group. The draft of the data set was developed by a working group consisting of members appointed by the Neurourology Committee of the International Continence Society, the European Association of Urology, the American Spinal Injury Association (ASIA), the International Spinal Cord Society (ISCoS) and a representative of the Executive Committee of the International SCI Standards and Data Sets. The final version of the data set was developed after review and comments by members of the Executive Committee of the International SCI Standards and Data Sets, the ISCoS Scientific Committee, ASIA Board, relevant and interested (international) organizations and societies (around 40) and persons and the ISCoS Council. Endorsement of the data set by relevant organizations and societies will be obtained. To make the data set uniform, each variable and each response category within each variable have been specifically defined in a way that is designed to promote the collection and reporting of comparable minimal data. Variables included in the International Urodynamic Basic SCI Data Set are date of data collection, bladder sensation during filling cystometry, detrusor function, compliance during filing cystometry, function during voiding, detrusor leak point pressure, maximum detrusor pressure, cystometric bladder capacity and post-void residual volume.

  11. Comparison of two models of a double inlet miniature pulse tube refrigerator: Part B electrical analogy

    NASA Astrophysics Data System (ADS)

    Bailly, Yannick; Nika, Philippe

    2002-10-01

    The design of a double inlet pulse tube refrigerator is investigated by means of an analogy with an electric circuit. The results obtained are compared with both those of the thermodynamic model (Part A) and experiments. The basic formulation of equivalent electronic components is discussed and a few improvements are proposed for adjusting the theoretical expressions of the electric impedance concerning the capillaries and the regenerator. Then additional effects such as pressure drops due to geometrical singularities are taken into account considering the different internal flow regimes that may occur. Besides a simplified formulation for the regenerator efficiency is deduced from considerations on its harmonic functioning. In this analysis, the emphasis concerns principally the design of miniature cryocoolers dedicated to electronic applications. Those models are applied to a commercial miniature refrigerator. A discussion of their relevance is achieved and a few suggestions on the refrigerator design are proposed in order to improve the cooling production.

  12. Troubleshooting crude vacuum tower overhead ejector systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lines, J.R.; Frens, L.L.

    1995-03-01

    Routinely surveying tower overhead vacuum systems can improve performance and product quality. These vacuum systems normally provide reliable and consistent operation. However, process conditions, supplied utilities, corrosion, erosion and fouling all have an impact on ejector system performance. Refinery vacuum distillation towers use ejector systems to maintain tower top pressure and remove overhead gases. However, as with virtually all refinery equipment, performance may be affected by a number of variables. These variables may act independently or concurrently. It is important to understand basic operating principles of vacuum systems and how performance is affected by: utilities, corrosion and erosion, fouling, andmore » process conditions. Reputable vacuum-system suppliers have service engineers that will come to a refinery to survey the system and troubleshoot performance or offer suggestions for improvement. A skilled vacuum-system engineer may be needed to diagnose and remedy system problems. The affect of these variables on performance is discussed. A case history is described of a vacuum system on a crude tower in a South American refinery.« less

  13. Growth kinetics of vertically aligned carbon nanotube arrays in clean oxygen-free conditions.

    PubMed

    In, Jung Bin; Grigoropoulos, Costas P; Chernov, Alexander A; Noy, Aleksandr

    2011-12-27

    Vertically aligned carbon nanotubes (CNTs) are an important technological system, as well as a fascinating system for studying basic principles of nanomaterials synthesis; yet despite continuing efforts for the past decade many important questions about this process remain largely unexplained. We present a series of parametric ethylene chemical vapor deposition growth studies in a "hot-wall" reactor using ultrapure process gases that reveal the fundamental kinetics of the CNT growth. Our data show that the growth rate is proportional to the concentration of the carbon feedstock and monotonically decreases with the concentration of hydrogen gas and that the most important parameter determining the rate of the CNT growth is the production rate of active carbon precursor in the gas phase reaction. The growth termination times obtained with the purified gas mixtures were strikingly insensitive to variations in both hydrogen and ethylene pressures ruling out the carbon encapsulation of the catalyst as the main process termination cause.

  14. Laser-Induced Breakdown Spectroscopy (LIBS) in a Novel Molten Salt Aerosol System.

    PubMed

    Williams, Ammon N; Phongikaroon, Supathorn

    2017-04-01

    In the pyrochemical separation of used nuclear fuel (UNF), fission product, rare earth, and actinide chlorides accumulate in the molten salt electrolyte over time. Measuring this salt composition in near real-time is advantageous for operational efficiency, material accountability, and nuclear safeguards. Laser-induced breakdown spectroscopy (LIBS) has been proposed and demonstrated as a potential analytical approach for molten LiCl-KCl salts. However, all the studies conducted to date have used a static surface approach which can lead to issues with splashing, low repeatability, and poor sample homogeneity. In this initial study, a novel molten salt aerosol approach has been developed and explored to measure the composition of the salt via LIBS. The functionality of the system has been demonstrated as well as a basic optimization of the laser energy and nebulizer gas pressure used. Initial results have shown that this molten salt aerosol-LIBS system has a great potential as an analytical technique for measuring the molten salt electrolyte used in this UNF reprocessing technology.

  15. Reproductive Parasitism: Maternally Inherited Symbionts in a Biparental World

    PubMed Central

    Hurst, Gregory D.D.; Frost, Crystal L.

    2015-01-01

    Most species of insect, and many other plants and animals, carry maternally heritable microorganisms—viruses, bacteria, unicellular eukaryotes, and fungi that pass from a female host to her progeny. Maternal inheritance establishes a correlation between the fitness of symbiont and host female, which can select for the symbiont to contribute to host fitness. Nevertheless, its lack of transmission through male hosts places the symbiont in conflict with biparentally inherited nuclear genes. In this review, we first examine how this conflict is manifest in selection to promote the production and survival of infected female hosts and gametes. We then examine how the distorted population sex ratios that they produce may affect host reproductive ecology, and thus the intensity of other conflicts associated with sexual reproduction. Finally, we examine evolved host responses to symbiont manipulation. We argue that the unusual intensity of symbiont–host conflict generates extreme selection pressures that can drive changes in sex-determination systems, the basic pathway through which males and females are constructed. PMID:25934011

  16. Asymmetric scattering by non-Hermitian potentials

    NASA Astrophysics Data System (ADS)

    Ruschhaupt, A.; Dowdall, T.; Simón, M. A.; Muga, J. G.

    2017-10-01

    The scattering of quantum particles by non-Hermitian (generally non-local) potentials in one dimension may result in asymmetric transmission and/or reflection from left and right incidence. After extending the concept of symmetry for non-Hermitian potentials, eight generalized symmetries based on the discrete Klein's four-group (formed by parity, time reversal, their product, and unity) are found. Together with generalized unitarity relations they determine selection rules for the possible and/or forbidden scattering asymmetries. Six basic device types are identified when the scattering coefficients (squared moduli of scattering amplitudes) adopt zero/one values, and transmission and/or reflection are asymmetric. They can pictorically be described as a one-way mirror, a one-way barrier (a Maxwell pressure demon), one-way (transmission or reflection) filters, a mirror with unidirectional transmission, and a transparent, one-way reflector. We design potentials for these devices and also demonstrate that the behavior of the scattering coefficients can be extended to a broad range of incident momenta.

  17. Inflammation in the pathophysiology of essential hypertension.

    PubMed

    Montecucco, Fabrizio; Pende, Aldo; Quercioli, Alessandra; Mach, François

    2011-01-01

    In spite of the huge amount of research recently performed in this area, the pathogenesis of human hypertension remains elusive. Thus, hypertension has to be defined as "essential" for the majority of patients with high blood pressure. Given the lack of animal models useful to investigate essential hypertension, we analyze and discuss both clinical and basic research studies indicating that essential hypertension should be considered as a potential multifactorial inflammatory disease. The pathophysiology of essential hypertension might result from interactions between genetic and environmental factors. Morphological abnormalities in the renal parenchyma and arteries have also been shown to determine hypertension. Inflammatory processes might induce renal vasoconstriction, ischemia and injury that can sustain systemic hypertension. Arterial and tubulointerstitial infiltration of inflammatory cells in response to renal damage might further increase renal and vascular alterations through the production of oxidants and other soluble inflammatory mediators. The present review gives an update regarding the latest research on the possible direct role of inflammation in the pathophysiology of essential hypertension.

  18. Mutiny over Bounty?

    PubMed

    Hutchison, T; Rolles, C J

    1984-06-09

    Bounty Services Ltd advertise commercial products on postnatal wards of hospitals throughout Britain by means of free gifts. Since the " Bounty lady" is apparently well known to nursing staff but may have gone unnoticed by paediatricians and obstetricians an investigation was conducted of the quality of the gifts and the nature of the company. With two exceptions the samples and promotional leaflets were sound, and mothers apparently enjoyed receiving them. Educational pamphlets distributed with the gifts were excellent, and cine films shown to the mothers were of good quality and informative about basic parental skills. Bounty , however, operates by exerting commercial pressure on new mothers at a time when they are most vulnerable and distributes materials among them without consultation with medical staff. Most of the mothers questioned assumed that the service was being provided by the NHS. The Bounty service may or may not be perceived as a satisfactory operation but details should be known to paediatricians and obstetricians; any action to be taken might be decided locally after discussion in individual hospitals or districts.

  19. A review of the hydrogeologic-geochemical model for Cerro Prieto

    USGS Publications Warehouse

    Lippmann, M.J.; Truesdell, A.H.; Halfman-Dooley, S. E.; Mañónm, A.

    1991-01-01

    With continued exploitation of the Cerro Prieto, Mexico, geothermal field, there is increasing evidence that the hydrogeologic model developed by Halfman and co-workers presents the basic features controlling the movement of geothermal fluids in the system. In mid-1987 the total installed capacity at Cerro Prieto reached 620 MWc, requiring a large rate of fluid production (more than 10,500 tonnes/hr of a brine-steam mixture; August 1988). This significant mass extraction has led to changes in reservoir thermodynamic conditions and in the chemistry of the produced fluids. Pressure drawdown has caused an increase in cold water recharge in the southern and western edges of the field, and local and general reservoir boiling in parts of the geothermal system. After reviewing the hydrogeologic and geochemical models of Cerro Prieto, the exploitation-induced cold water recharge and reservoir boiling (and plugging) observed in different areas of the field, are discussed and interpreted on the basis of these models and schematic flow models that describe the hydrogeology. ?? 1991.

  20. Teaching English in the World

    ERIC Educational Resources Information Center

    Lindblom, Kenneth

    2004-01-01

    English and writing teachers are often pressurized to return to the basics of grammar, despite the evidence that drilling grammar does not improve students' writing skills. A great disparity exists between public perception of effective education and the perception of professional educators, which is the main reason why parents and government…

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